# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF3552 PF12072.8 CBY06692.1 - 0.0035 16.8 14.2 0.0035 16.8 14.2 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3552) ATG16 PF08614.11 CBY06692.1 - 0.014 15.6 25.4 0.014 15.6 25.4 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Pkinase PF00069.25 CBY06693.1 - 8.8e-58 195.7 0.0 3.8e-57 193.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 CBY06693.1 - 1.1e-31 108.7 0.9 3.5e-15 55.9 0.2 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY06693.1 - 4.1e-29 101.6 0.0 9.2e-28 97.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY06693.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RLL PF10036.9 CBY06693.1 - 0.13 12.0 1.9 0.52 10.1 1.9 1.9 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein C2 PF00168.30 CBY06698.1 - 1.5e-48 163.3 0.3 4.2e-23 81.6 0.1 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CBY06698.1 - 0.0045 16.6 0.0 0.016 14.8 0.0 2.0 1 0 0 1 1 1 1 CEP76 C2 domain CRR7 PF12095.8 CBY06698.1 - 0.067 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF3546 PF12066.8 CBY06698.1 - 0.11 12.7 1.4 0.16 12.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) fn3 PF00041.21 CBY06699.1 - 1.4e-20 73.4 12.2 2.8e-06 27.6 0.1 4.6 3 1 2 5 5 5 4 Fibronectin type III domain IGFL PF14653.6 CBY06699.1 - 0.018 15.0 6.0 0.036 14.0 6.0 1.5 1 0 0 1 1 1 0 Insulin growth factor-like family C2-set_2 PF08205.12 CBY06700.1 - 0.25 11.4 7.9 0.24 11.5 5.2 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Mucin PF01456.17 CBY06700.1 - 0.51 10.3 29.0 1 9.3 27.9 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.11 CBY06700.1 - 0.88 7.7 20.6 1.3 7.1 20.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 CBY06700.1 - 1.7 8.6 17.9 4 7.4 17.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CBY06700.1 - 7.8 4.3 7.8 11 3.9 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 CBY06700.1 - 8.6 4.3 13.3 12 3.9 13.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sporozoite_P67 PF05642.11 CBY06700.1 - 9.7 4.1 8.5 14 3.6 8.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoside_tran PF01733.18 CBY06701.1 - 1e-36 126.9 8.9 1e-36 126.9 8.9 2.4 1 1 1 2 2 2 1 Nucleoside transporter Sugar_tr PF00083.24 CBY06701.1 - 0.00099 18.1 15.9 0.00099 18.1 15.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY06701.1 - 0.64 8.9 38.1 14 4.5 37.1 2.9 1 1 0 1 1 1 0 Major Facilitator Superfamily Ank_2 PF12796.7 CBY06702.1 - 9e-05 23.0 0.0 0.041 14.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY06702.1 - 0.00039 20.9 0.0 0.011 16.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY06702.1 - 0.00091 19.5 0.0 5.9 7.8 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CBY06702.1 - 0.021 15.1 0.0 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) SdpA PF17418.2 CBY06702.1 - 0.028 14.3 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Sporulation delaying protein SdpA Sec34 PF04136.15 CBY06702.1 - 0.038 13.9 0.3 0.089 12.7 0.3 1.7 1 1 0 1 1 1 0 Sec34-like family TBCC_N PF16752.5 CBY06702.1 - 0.15 12.5 1.1 0.33 11.4 1.1 1.5 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain YkyA PF10368.9 CBY06702.1 - 1.4 8.6 5.6 24 4.5 3.2 2.1 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein HlyIII PF03006.20 CBY06703.1 - 4.5e-06 26.5 1.2 5.7e-06 26.2 1.2 1.2 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 CBY06703.1 - 0.0081 16.2 1.4 0.011 15.8 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) ExoD PF06055.12 CBY06703.1 - 0.023 14.1 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD HlyIII PF03006.20 CBY06704.1 - 2.3e-22 79.8 7.0 2.6e-22 79.6 7.0 1.0 1 0 0 1 1 1 1 Haemolysin-III related Galactosyl_T PF01762.21 CBY06705.1 - 1.3e-07 31.7 0.1 7.4e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 Galactosyltransferase DUF3439 PF11921.8 CBY06706.1 - 0.072 13.1 2.2 0.34 10.9 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ion_trans_2 PF07885.16 CBY06707.1 - 2.3e-27 94.8 24.6 7.7e-14 51.4 13.7 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CBY06707.1 - 1.8e-07 30.7 10.6 0.00029 20.2 0.0 2.4 1 1 1 2 2 2 2 Ion transport protein DUF4383 PF14325.6 CBY06707.1 - 0.075 13.3 3.3 0.19 12.0 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) Sulfotransfer_2 PF03567.14 CBY06708.1 - 3.9e-08 33.5 0.1 7e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family MFS_2 PF13347.6 CBY06709.1 - 1.2e-06 27.3 5.3 1.3e-06 27.3 5.3 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CBY06709.1 - 2.3e-06 26.8 5.1 2.6e-06 26.6 5.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBY06709.1 - 0.04 12.2 0.9 0.049 11.9 0.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sulfotransfer_2 PF03567.14 CBY06711.1 - 2.6e-15 57.0 0.2 4e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY06711.1 - 0.0038 16.8 0.1 0.01 15.4 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain NLRC4_HD2 PF17776.1 CBY06711.1 - 0.11 13.1 0.1 0.23 12.0 0.1 1.5 1 0 0 1 1 1 0 NLRC4 helical domain HD2 Sulfotransfer_2 PF03567.14 CBY06712.1 - 2.7e-05 24.2 0.1 6.8e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY06712.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain YhzD PF14120.6 CBY06713.1 - 0.052 13.7 1.4 0.071 13.2 1.4 1.2 1 0 0 1 1 1 0 YhzD-like protein EF-hand_6 PF13405.6 CBY06714.1 - 3.7e-13 48.2 6.7 0.009 15.9 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 CBY06714.1 - 1.9e-12 45.8 11.3 0.0075 15.7 0.1 4.5 3 1 1 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY06714.1 - 3.9e-12 46.4 5.9 1.6e-06 28.4 1.4 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY06714.1 - 1.2e-06 27.8 8.7 0.11 12.1 0.3 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY06714.1 - 0.00034 20.4 8.2 2.6 8.0 0.5 4.6 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY06714.1 - 0.0044 17.3 3.6 0.017 15.4 0.6 3.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CBY06714.1 - 0.083 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Dockerin type I domain DUF1989 PF09347.10 CBY06714.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) 7tm_1 PF00001.21 CBY06715.1 - 0.00031 20.2 0.3 0.00034 20.0 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.27 CBY06717.1 - 3e-31 108.7 0.2 1e-30 106.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_HK97_TLTM PF06120.11 CBY06717.1 - 0.013 14.8 3.1 0.06 12.5 3.1 2.2 1 0 0 1 1 1 0 Tail length tape measure protein NPA PF16469.5 CBY06717.1 - 0.73 10.4 6.0 2.4 8.7 0.1 4.1 3 0 0 3 3 3 0 Nematode polyprotein allergen ABA-1 Lectin_C PF00059.21 CBY06718.1 - 0.02 15.6 0.1 0.07 13.9 0.0 1.8 2 0 0 2 2 2 0 Lectin C-type domain T4_deiodinase PF00837.17 CBY06719.1 - 2.7e-27 95.6 0.0 3e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Choline_kinase PF01633.20 CBY06721.1 - 5.7e-09 35.9 0.2 4.8e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CBY06721.1 - 3.6e-07 30.4 0.0 5.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY06721.1 - 0.019 14.3 0.7 0.019 14.3 0.7 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase RT_RNaseH_2 PF17919.1 CBY06723.1 - 6.2e-14 51.9 0.0 2.4e-13 50.0 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY06723.1 - 9.7e-11 41.6 0.0 2.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CBY06723.1 - 1.1e-10 41.7 0.0 5.1e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY06723.1 - 8e-05 22.7 1.4 0.00011 22.3 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Peptidase_C78 PF07910.13 CBY06723.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 DUF498 PF04430.14 CBY06723.1 - 0.12 12.4 0.0 3.2 7.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Phage_Cox PF10743.9 CBY06725.1 - 0.06 13.4 0.2 0.073 13.2 0.2 1.2 1 0 0 1 1 1 0 Regulatory phage protein cox LapA_dom PF06305.11 CBY06726.1 - 0.00092 19.0 0.2 0.0015 18.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain EGF_2 PF07974.13 CBY06726.1 - 0.0018 18.6 7.7 0.0029 18.0 7.7 1.3 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 CBY06726.1 - 0.0049 17.1 1.7 0.0049 17.1 1.7 1.8 1 1 1 2 2 2 1 EGF-like domain Squash PF00299.18 CBY06726.1 - 0.022 14.8 1.4 0.022 14.8 1.4 1.8 2 0 0 2 2 2 0 Squash family serine protease inhibitor DUF4083 PF13314.6 CBY06726.1 - 0.063 13.2 1.0 0.089 12.8 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF1211 PF06736.11 CBY06726.1 - 0.09 13.2 0.1 0.1 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) UPF0154 PF03672.13 CBY06726.1 - 0.13 12.3 0.3 0.2 11.7 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Glycophorin_A PF01102.18 CBY06726.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycophorin A DUF4834 PF16118.5 CBY06726.1 - 0.41 11.6 2.2 0.51 11.3 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Neur_chan_LBD PF02931.23 CBY06728.1 - 1.5e-23 83.4 0.3 2.2e-23 82.8 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY06728.1 - 2e-16 60.8 15.9 1.2e-14 55.0 6.9 3.1 2 1 1 3 3 3 3 Neurotransmitter-gated ion-channel transmembrane region Zona_pellucida PF00100.23 CBY06729.1 - 0.029 14.2 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Zona pellucida-like domain Tautomerase PF01361.21 CBY06730.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme Sod_Cu PF00080.20 CBY06732.1 - 7.9e-62 207.6 19.0 1.7e-31 109.3 5.7 2.3 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) An_peroxidase PF03098.15 CBY06733.1 - 1.1e-157 525.8 0.0 1.3e-157 525.6 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Sushi PF00084.20 CBY06733.1 - 1.5e-05 25.5 1.0 4.6e-05 23.9 1.0 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF2232 PF09991.9 CBY06733.1 - 0.073 12.3 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FXa_inhibition PF14670.6 CBY06733.1 - 0.51 10.7 12.3 0.037 14.3 4.5 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site zf-CXXC PF02008.20 CBY06734.1 - 4.2e-07 29.9 20.6 7.1e-07 29.2 20.6 1.3 1 0 0 1 1 1 1 CXXC zinc finger domain NPV_P10 PF05531.12 CBY06735.1 - 0.017 15.6 7.1 0.095 13.2 0.5 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Nnf1 PF03980.14 CBY06735.1 - 0.091 13.1 0.4 0.091 13.1 0.4 3.6 3 0 0 3 3 3 0 Nnf1 MapZ_EC1 PF18041.1 CBY06735.1 - 0.34 11.1 6.7 0.1 12.8 1.0 2.7 2 1 0 2 2 2 0 MapZ extracellular domain 1 Phospholip_A2_1 PF00068.19 CBY06736.1 - 9.1e-14 51.9 11.2 9.1e-14 51.9 11.2 2.3 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY06737.1 - 0.19 12.2 0.7 0.28 11.6 0.7 1.3 1 0 0 1 1 1 0 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY06738.1 - 1.8e-13 50.9 3.7 3.1e-13 50.2 3.7 1.3 1 0 0 1 1 1 1 Phospholipase A2 DUF1493 PF07377.12 CBY06738.1 - 0.063 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) EB PF01683.18 CBY06738.1 - 2.4 8.5 11.4 78 3.7 11.4 2.6 1 1 0 1 1 1 0 EB module O-FucT PF10250.9 CBY06739.1 - 4.8e-13 49.5 0.2 1.9e-12 47.6 0.2 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Phage_FRD3 PF05798.11 CBY06739.1 - 0.064 13.5 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 Bacteriophage FRD3 protein Trypsin PF00089.26 CBY06740.1 - 1.5e-50 172.0 0.4 3.3e-49 167.7 0.4 2.2 1 1 0 1 1 1 1 Trypsin Kringle PF00051.18 CBY06740.1 - 1.3e-16 60.7 8.8 3.4e-16 59.3 8.8 1.8 1 0 0 1 1 1 1 Kringle domain Trypsin_2 PF13365.6 CBY06740.1 - 0.0006 20.7 0.0 0.0014 19.6 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Zona_pellucida PF00100.23 CBY06742.1 - 3.3e-25 89.4 3.3 3.3e-25 89.4 3.3 1.8 2 0 0 2 2 2 1 Zona pellucida-like domain FXa_inhibition PF14670.6 CBY06742.1 - 1.2 9.5 17.1 0.09 13.1 10.7 2.6 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site Thyroglobulin_1 PF00086.18 CBY06743.1 - 1.5e-08 34.2 0.6 4.5e-08 32.7 0.1 1.9 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat PMP22_Claudin PF00822.20 CBY06744.1 - 5.6e-08 32.8 11.8 7.9e-08 32.3 11.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY06744.1 - 4.4e-05 23.7 8.6 0.00016 22.0 7.5 2.1 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CBY06744.1 - 0.00022 21.1 16.0 0.0042 16.9 16.0 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.6 CBY06744.1 - 0.0032 17.4 1.3 0.0032 17.4 1.3 1.9 1 1 1 2 2 2 1 Voltage-dependent calcium channel gamma-like subunit protein family EphA2_TM PF14575.6 CBY06744.1 - 0.12 13.2 0.1 0.75 10.7 0.0 2.3 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain PsbY PF06298.11 CBY06744.1 - 0.13 12.2 3.3 0.85 9.6 0.4 3.3 3 0 0 3 3 3 0 Photosystem II protein Y (PsbY) Trypsin PF00089.26 CBY06745.1 - 3.1e-21 76.2 4.6 3.2e-19 69.6 0.2 2.1 2 0 0 2 2 2 2 Trypsin Ank_2 PF12796.7 CBY06746.1 - 4.7e-146 475.7 65.9 1.5e-15 57.5 0.6 11.7 2 1 12 15 15 15 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY06746.1 - 1.2e-100 328.6 28.8 2e-11 44.2 0.1 15.7 8 5 8 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY06746.1 - 5e-85 269.2 27.9 3.9e-05 23.7 0.0 23.6 23 0 0 23 23 23 19 Ankyrin repeat Ank PF00023.30 CBY06746.1 - 9.3e-85 275.7 59.0 1.7e-05 25.1 0.0 22.6 22 0 0 22 22 22 20 Ankyrin repeat Ank_5 PF13857.6 CBY06746.1 - 1.1e-78 258.2 40.3 3.6e-08 33.5 0.0 18.3 6 4 13 19 19 19 16 Ankyrin repeats (many copies) ZU5 PF00791.20 CBY06746.1 - 1.5e-20 73.4 0.0 1e-17 64.3 0.0 2.8 2 0 0 2 2 2 2 ZU5 domain UPA_2 PF17809.1 CBY06746.1 - 4.4e-06 26.6 0.0 1.2e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 UPA domain TBCA PF02970.16 CBY06746.1 - 0.0033 17.7 5.2 0.028 14.7 5.2 2.7 1 0 0 1 1 1 1 Tubulin binding cofactor A PNP_UDP_1 PF01048.20 CBY06747.1 - 1.4e-18 67.0 0.0 1.6e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Caprin-1_dimer PF18293.1 CBY06747.1 - 0.12 12.9 0.0 2 8.9 0.0 2.4 2 1 0 2 2 2 0 Caprin-1 dimerization domain RNase_P_Rpp14 PF01900.19 CBY06747.1 - 0.14 12.4 0.6 0.72 10.1 0.1 2.3 3 0 0 3 3 3 0 Rpp14/Pop5 family DUF2070 PF09843.9 CBY06748.1 - 4.8 5.4 6.9 6.2 5.0 6.7 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Methyltransf_11 PF08241.12 CBY06749.1 - 1.3e-15 57.8 0.0 3.6e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY06749.1 - 5.8e-13 49.4 0.0 1.6e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY06749.1 - 2.3e-10 40.6 0.0 3.7e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY06749.1 - 3e-08 33.6 0.3 2.1e-07 30.9 0.3 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY06749.1 - 4.6e-07 30.5 0.0 1.5e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CBY06749.1 - 1.3e-05 25.1 0.1 2e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 CBY06749.1 - 4.3e-05 23.2 0.1 6.7e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW 2OG-FeII_Oxy_2 PF13532.6 CBY06749.1 - 5.2e-05 23.5 0.2 9.1e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ubie_methyltran PF01209.18 CBY06749.1 - 0.00027 20.3 0.1 0.0099 15.2 0.1 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 CBY06749.1 - 0.0036 16.7 0.0 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Pox_MCEL PF03291.16 CBY06749.1 - 0.0053 15.9 0.3 1.7 7.6 0.1 2.2 1 1 1 2 2 2 2 mRNA capping enzyme DUF1904 PF08921.11 CBY06750.1 - 0.082 13.2 0.4 0.2 12.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) Pkinase_Tyr PF07714.17 CBY06751.1 - 4.1e-25 88.5 0.0 5.7e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY06751.1 - 3.1e-21 75.9 0.0 5e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 CBY06751.1 - 0.06 12.8 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 CBY06751.1 - 0.087 13.9 12.3 0.5 11.5 12.3 2.3 1 1 0 1 1 1 0 Activin types I and II receptor domain Cu-oxidase_3 PF07732.15 CBY06752.1 - 2.6e-37 127.4 0.2 2.4e-36 124.3 0.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CBY06752.1 - 1.8e-24 86.0 2.6 1.3e-19 70.3 0.0 3.4 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 CBY06752.1 - 1.4e-09 38.2 0.2 1.3e-06 28.7 0.0 3.6 3 1 0 3 3 3 2 Multicopper oxidase Calx-beta PF03160.14 CBY06752.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Calx-beta domain cNMP_binding PF00027.29 CBY06753.1 - 2.1e-40 136.7 0.2 2.7e-15 56.2 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CBY06753.1 - 1.6e-13 51.3 0.0 4.9e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase ECF_trnsprt PF12822.7 CBY06753.1 - 0.93 9.6 3.5 0.35 10.9 0.6 1.7 2 0 0 2 2 2 0 ECF transporter, substrate-specific component PHO4 PF01384.20 CBY06756.1 - 3.3e-119 397.9 8.7 4.6e-119 397.4 8.7 1.2 1 0 0 1 1 1 1 Phosphate transporter family GLYCAM-1 PF05242.11 CBY06756.1 - 0.14 12.3 1.2 0.26 11.4 1.2 1.3 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Sulfatase PF00884.23 CBY06757.1 - 2e-46 158.8 0.2 2.9e-24 86.0 0.2 2.5 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.22 CBY06757.1 - 7.2e-07 29.1 0.1 0.0024 17.5 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase ASL_C2 PF14698.6 CBY06757.1 - 0.1 13.3 0.0 0.3 11.9 0.0 1.7 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal Kelch_1 PF01344.25 CBY06758.1 - 0.00043 19.8 2.5 0.00094 18.7 0.9 2.5 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY06758.1 - 0.0027 17.9 3.8 0.091 13.1 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY06758.1 - 0.015 15.3 1.0 0.075 13.0 0.0 2.7 4 0 0 4 4 4 0 Kelch motif Ras PF00071.22 CBY06759.1 - 3e-43 147.2 0.4 3.8e-43 146.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY06759.1 - 3.2e-28 98.4 0.1 7.1e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY06759.1 - 7.3e-13 48.3 0.0 9.6e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CBY06759.1 - 9.3e-05 22.2 0.2 0.0038 17.0 0.2 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 CBY06759.1 - 0.00018 21.0 0.1 0.00023 20.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY06759.1 - 0.00051 20.1 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY06759.1 - 0.00077 19.4 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CBY06759.1 - 0.0045 17.4 0.0 0.006 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY06759.1 - 0.009 16.3 0.0 0.34 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CBY06759.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBY06759.1 - 0.017 15.0 0.0 0.097 12.6 0.0 2.1 2 1 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 CBY06759.1 - 0.047 13.7 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DC_STAMP PF07782.13 CBY06759.1 - 0.047 13.5 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein ATP_bind_1 PF03029.17 CBY06759.1 - 0.082 12.7 0.5 3.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 CBY06759.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.20 CBY06760.1 - 7.7e-61 202.5 0.2 1.7e-28 98.6 0.0 4.6 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 CBY06760.1 - 7.7e-18 65.0 12.2 1e-14 54.9 2.8 4.3 3 2 2 5 5 5 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CBY06760.1 - 8.9e-10 38.4 0.5 0.0015 18.0 0.0 4.1 2 1 1 4 4 4 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CBY06760.1 - 2e-09 37.4 0.1 0.0017 18.2 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CBY06760.1 - 2.5e-07 30.9 0.2 0.35 11.2 0.0 4.7 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CBY06760.1 - 4.4e-07 30.3 5.1 0.048 14.1 0.2 5.0 4 2 0 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.17 CBY06760.1 - 3.3e-06 26.4 2.2 1.3e-05 24.5 1.2 2.3 1 1 0 1 1 1 1 Calsequestrin Redoxin PF08534.10 CBY06760.1 - 8e-05 22.4 0.2 0.091 12.5 0.0 2.6 3 0 0 3 3 3 2 Redoxin Thioredoxin_7 PF13899.6 CBY06760.1 - 0.0001 22.4 0.0 0.046 13.9 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like Glyco_transf_24 PF18404.1 CBY06760.1 - 0.0042 16.5 0.5 0.0066 15.9 0.5 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 HyaE PF07449.11 CBY06760.1 - 0.0042 17.0 0.0 9.6 6.2 0.0 4.2 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 CBY06760.1 - 0.0086 16.1 0.0 0.076 13.1 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin domain TraF PF13728.6 CBY06760.1 - 0.046 13.5 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 F plasmid transfer operon protein SeleniumBinding PF11524.8 CBY06760.1 - 0.095 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Selenium binding protein Glutaredoxin PF00462.24 CBY06760.1 - 0.11 12.8 0.6 27 5.1 0.0 3.3 2 1 0 2 2 2 0 Glutaredoxin Thioredoxin_4 PF13462.6 CBY06760.1 - 0.12 12.5 2.6 4.3 7.5 0.0 3.1 3 1 0 3 3 3 0 Thioredoxin CIA30 PF08547.12 CBY06761.1 - 1.2e-15 57.9 0.8 1.4e-15 57.7 0.8 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_4_9 PF02018.17 CBY06761.1 - 0.013 15.8 1.3 0.024 14.9 1.3 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain DUF3504 PF12012.8 CBY06762.1 - 3e-05 24.0 1.1 0.00017 21.5 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3504) CUB PF00431.20 CBY06763.1 - 0.0001 22.6 0.9 0.058 13.7 0.1 3.6 3 0 0 3 3 3 2 CUB domain IL12p40_C PF10420.9 CBY06763.1 - 0.00027 21.4 0.1 0.0015 19.0 0.0 2.3 2 0 0 2 2 2 1 Cytokine interleukin-12p40 C-terminus OCRE PF17780.1 CBY06764.1 - 0.0021 18.1 16.0 0.0032 17.5 0.6 2.5 1 1 1 2 2 2 2 OCRE domain Prion PF00377.18 CBY06765.1 - 1.5 8.7 5.1 0.37 10.7 0.1 2.1 1 1 1 2 2 2 0 Prion/Doppel alpha-helical domain Vac_ImportDeg PF09783.9 CBY06765.1 - 6.8 6.5 15.0 1e+03 -0.6 15.0 2.7 1 1 0 1 1 1 0 Vacuolar import and degradation protein zf-C4 PF00105.18 CBY06766.1 - 1.3e-09 38.3 15.1 3.5e-09 37.0 15.1 1.7 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-C4 PF00105.18 CBY06767.1 - 5.3e-14 52.4 8.4 1.1e-13 51.4 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RB_A PF01858.17 CBY06768.1 - 4.9e-47 160.3 1.4 4.9e-47 160.3 1.4 2.1 2 1 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 CBY06768.1 - 5.5e-38 130.0 3.8 1.1e-36 125.8 2.2 2.8 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 CBY06768.1 - 5.7e-38 129.6 0.1 1.7e-36 124.8 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) Rb_C PF08934.10 CBY06768.1 - 0.0014 18.5 0.3 0.0035 17.2 0.3 1.6 1 0 0 1 1 1 1 Rb C-terminal domain TFIIB PF00382.19 CBY06768.1 - 0.013 15.5 0.0 2.9 8.0 0.0 2.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat CSD PF00313.22 CBY06769.1 - 9.2e-59 195.2 27.1 6.8e-13 48.3 0.3 9.4 9 1 0 9 9 9 8 'Cold-shock' DNA-binding domain S1-like PF14444.6 CBY06769.1 - 1.5e-07 31.3 8.2 0.054 13.4 0.1 5.5 5 0 0 5 5 5 2 S1-like CusF_Ec PF11604.8 CBY06769.1 - 0.022 14.7 5.6 4.5 7.3 0.0 4.9 6 0 0 6 6 6 0 Copper binding periplasmic protein CusF MAM PF00629.23 CBY06769.1 - 0.049 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu S1 PF00575.23 CBY06769.1 - 0.18 12.1 7.0 14 6.1 0.1 4.4 5 0 0 5 5 5 0 S1 RNA binding domain OB_RNB PF08206.11 CBY06769.1 - 2.8 7.7 9.1 8.2 6.2 0.1 4.6 5 0 0 5 5 5 0 Ribonuclease B OB domain SLATT_6 PF18169.1 CBY06771.1 - 0.29 10.7 1.5 0.73 9.4 1.5 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 NAD_binding_6 PF08030.12 CBY06773.1 - 1.6e-28 99.8 0.0 3.4e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CBY06773.1 - 3.6e-19 68.8 0.0 1e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CBY06773.1 - 8.3e-17 61.5 6.3 1.9e-16 60.3 6.3 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 CBY06773.1 - 0.0029 18.2 0.0 0.015 16.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Herpes_UL32 PF06070.11 CBY06773.1 - 0.25 9.0 0.0 0.37 8.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Dimer_Tnp_hAT PF05699.14 CBY06775.1 - 1.2e-09 37.8 0.1 1.8e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PLAC8 PF04749.17 CBY06777.1 - 3.2e-14 53.7 3.8 4.3e-14 53.3 3.8 1.2 1 0 0 1 1 1 1 PLAC8 family ORC2 PF04084.14 CBY06778.1 - 0.091 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 2 DUF3242 PF11586.8 CBY06779.1 - 0.0096 15.6 0.5 0.064 13.0 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3242) DUF473 PF04322.12 CBY06779.1 - 0.21 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF473) DUF3525 PF12039.8 CBY06780.1 - 0.01 14.6 0.1 0.078 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) Gal_Lectin PF02140.18 CBY06781.1 - 5.3e-14 52.4 2.5 1.2e-13 51.3 2.5 1.6 1 0 0 1 1 1 1 Galactose binding lectin domain DUF2761 PF10959.8 CBY06781.1 - 0.034 14.1 0.0 2.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2761) GST_N PF02798.20 CBY06782.1 - 8.6e-06 26.0 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY06782.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY06782.1 - 0.021 15.0 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 CBY06782.1 - 0.062 13.6 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex Trypsin PF00089.26 CBY06783.1 - 6e-46 157.0 0.0 7.1e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY06783.1 - 3.3e-05 24.8 0.0 5.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY06783.1 - 0.035 14.5 0.0 0.06 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Lipocalin PF00061.23 CBY06784.1 - 7.8e-15 55.3 3.0 9.4e-15 55.1 3.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 CBY06784.1 - 9.2e-10 38.5 0.7 1e-09 38.4 0.7 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family OCRE PF17780.1 CBY06785.1 - 0.038 14.0 12.4 0.31 11.1 1.7 2.6 2 1 0 2 2 2 0 OCRE domain Nit_Regul_Hom PF10126.9 CBY06785.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII ITI_HC_C PF06668.12 CBY06787.1 - 0.00081 19.1 0.2 0.005 16.5 0.2 2.0 1 1 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus CCB1 PF12046.8 CBY06787.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B PLAC8 PF04749.17 CBY06788.1 - 1.5e-10 41.9 0.3 1.7e-10 41.7 0.3 1.1 1 0 0 1 1 1 1 PLAC8 family DM PF00751.18 CBY06788.1 - 0.042 13.7 0.5 0.064 13.2 0.5 1.3 1 0 0 1 1 1 0 DM DNA binding domain DUF1084 PF06454.11 CBY06788.1 - 0.069 12.5 0.1 0.071 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) Connexin PF00029.19 CBY06789.1 - 1.3e-72 244.3 12.1 3.6e-72 242.9 9.7 2.5 2 1 0 2 2 2 1 Connexin CAF1C_H4-bd PF12265.8 CBY06789.1 - 0.015 15.5 0.2 0.028 14.7 0.2 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex CLN3 PF02487.17 CBY06789.1 - 0.07 12.2 1.0 2.1 7.3 0.2 2.3 2 0 0 2 2 2 0 CLN3 protein Na_sulph_symp PF00939.19 CBY06790.1 - 1.8e-81 274.6 12.0 2.2e-81 274.3 12.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY06790.1 - 4.3e-32 111.5 17.9 1.5e-17 63.8 8.3 3.2 2 1 1 3 3 3 3 Citrate transporter Trypsin PF00089.26 CBY06791.1 - 1.4e-41 142.7 1.4 2.1e-41 142.2 1.4 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY06791.1 - 8.9e-08 33.2 0.5 1.8e-07 32.2 0.2 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY06791.1 - 0.0013 18.3 0.2 0.31 10.6 0.0 2.7 3 0 0 3 3 3 2 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 CBY06791.1 - 0.0039 17.5 0.7 0.008 16.6 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) EGF PF00008.27 CBY06791.1 - 0.35 11.2 3.3 1.6 9.1 3.3 2.2 1 0 0 1 1 1 0 EGF-like domain TRAM_LAG1_CLN8 PF03798.16 CBY06792.1 - 0.091 12.5 11.2 0.1 12.3 11.2 1.0 1 0 0 1 1 1 0 TLC domain Proteasome PF00227.26 CBY06794.1 - 1.2e-42 145.5 0.1 1.6e-42 145.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBY06794.1 - 3.7e-14 52.1 0.0 6e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WD40 PF00400.32 CBY06795.1 - 2.1e-07 31.5 16.6 2.2e-05 25.1 0.4 5.2 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY06795.1 - 1.5e-05 25.2 1.5 0.21 11.9 0.0 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PDZ PF00595.24 CBY06796.1 - 4.6e-06 26.9 0.2 5.7e-06 26.6 0.2 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY06796.1 - 0.014 15.7 0.1 0.017 15.5 0.1 1.3 1 0 0 1 1 1 0 PDZ domain YaeQ PF07152.12 CBY06796.1 - 0.024 14.3 0.1 0.027 14.1 0.1 1.0 1 0 0 1 1 1 0 YaeQ protein PDZ_6 PF17820.1 CBY06796.1 - 0.042 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 PDZ domain DUF2807 PF10988.8 CBY06796.1 - 0.052 13.3 1.1 0.23 11.3 1.1 1.8 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain adh_short PF00106.25 CBY06797.1 - 3.2e-13 49.6 0.0 4.4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY06797.1 - 5.6e-06 26.1 0.0 7.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TIL PF01826.17 CBY06798.1 - 1.9e-05 24.8 7.5 1.9e-05 24.8 7.5 2.0 2 0 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain DUF3314 PF11771.8 CBY06798.1 - 0.092 12.9 0.6 0.59 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) TILa PF12714.7 CBY06798.1 - 0.15 12.1 6.5 0.57 10.2 6.5 2.0 1 0 0 1 1 1 0 TILa domain Phospholip_A2_1 PF00068.19 CBY06799.1 - 6.8e-19 68.4 9.4 6.8e-19 68.4 9.4 1.9 2 0 0 2 2 2 1 Phospholipase A2 PLAC8 PF04749.17 CBY06800.1 - 1.7e-16 61.0 4.4 2.1e-16 60.7 4.4 1.1 1 0 0 1 1 1 1 PLAC8 family ORC2 PF04084.14 CBY06801.1 - 0.081 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 2 HMG_box_2 PF09011.10 CBY06802.1 - 2.3e-22 79.4 15.8 7.9e-13 48.8 1.8 3.6 3 0 0 3 3 3 3 HMG-box domain HMG_box PF00505.19 CBY06802.1 - 2.5e-22 79.1 24.3 3.7e-11 43.3 0.6 4.2 4 0 0 4 4 4 3 HMG (high mobility group) box Protamine_like PF06382.11 CBY06802.1 - 0.001 19.3 7.6 0.0034 17.6 1.4 2.5 2 0 0 2 2 2 2 Protamine and protamine like KDZ PF18758.1 CBY06802.1 - 0.0065 16.1 0.3 0.0065 16.1 0.3 2.4 3 0 0 3 3 3 1 Kyakuja-Dileera-Zisupton transposase DUF1289 PF06945.13 CBY06802.1 - 0.24 11.2 0.6 22 5.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Methyltransf_31 PF13847.6 CBY06803.1 - 1.7e-31 109.1 0.0 2.8e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY06803.1 - 1.6e-19 70.4 0.1 2.8e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY06803.1 - 3.4e-19 69.3 0.0 6.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY06803.1 - 7e-14 52.0 0.0 1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY06803.1 - 1.4e-13 51.4 0.1 2.7e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY06803.1 - 2.6e-12 46.6 0.0 3.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CBY06803.1 - 3.4e-07 30.4 0.1 2.4e-05 24.3 0.1 2.4 2 0 0 2 2 2 1 Hypothetical methyltransferase PrmA PF06325.13 CBY06803.1 - 4.3e-07 29.6 0.0 6.5e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CBY06803.1 - 7.7e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CBY06803.1 - 0.00023 20.8 0.0 0.00057 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 CBY06803.1 - 0.001 18.6 0.0 0.081 12.4 0.0 2.2 1 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 CBY06803.1 - 0.0039 16.7 0.0 0.37 10.3 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Fibrillarin PF01269.17 CBY06803.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.19 CBY06803.1 - 0.037 14.1 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase TPMT PF05724.11 CBY06803.1 - 0.055 13.1 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 CBY06803.1 - 0.082 12.2 0.0 0.44 9.8 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CBY06803.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 CBY06803.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.17 CBY06803.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_9 PF08003.11 CBY06803.1 - 0.17 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Chlam_PMP PF02415.17 CBY06804.1 - 2.7 8.6 9.1 5.2 7.8 9.1 1.5 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Sugar_tr PF00083.24 CBY06805.1 - 4.7e-24 85.1 13.3 1.8e-23 83.2 13.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY06805.1 - 3e-20 72.5 14.4 3.7e-14 52.4 9.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CBY06805.1 - 0.00011 21.6 0.1 0.00011 21.6 0.1 1.5 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3981 PF13139.6 CBY06805.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) PhnA_Zn_Ribbon PF08274.12 CBY06805.1 - 0.087 12.8 0.5 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Mut7-C PF01927.16 CBY06805.1 - 0.099 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain UPF0016 PF01169.19 CBY06806.1 - 9.1e-35 118.8 16.3 1.4e-19 70.2 8.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Ctr PF04145.15 CBY06806.1 - 1.4 9.6 5.1 1.3 9.6 1.8 2.7 1 1 1 2 2 2 0 Ctr copper transporter family EGF_3 PF12947.7 CBY06807.1 - 2.4e-07 30.8 28.3 8.2e-06 25.9 6.4 3.6 3 0 0 3 3 3 2 EGF domain Lectin_C PF00059.21 CBY06807.1 - 1.2e-05 25.9 0.2 1.2e-05 25.9 0.2 2.1 2 0 0 2 2 2 1 Lectin C-type domain Plasmod_Pvs28 PF06247.11 CBY06807.1 - 0.011 16.0 4.9 0.011 16.0 4.9 3.8 4 0 0 4 4 4 0 Pvs28 EGF domain EGF PF00008.27 CBY06807.1 - 2.6 8.4 26.9 0.066 13.5 3.1 4.5 3 1 0 3 3 3 0 EGF-like domain cEGF PF12662.7 CBY06807.1 - 6.3 6.8 12.0 1.4 9.0 0.7 3.4 3 0 0 3 3 3 0 Complement Clr-like EGF-like Lectin_C PF00059.21 CBY06808.1 - 0.015 16.0 0.1 0.015 16.0 0.1 2.1 2 1 0 2 2 2 0 Lectin C-type domain Collagen PF01391.18 CBY06810.1 - 9.4e-19 66.9 83.4 2.9e-08 33.3 31.2 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Kelch_6 PF13964.6 CBY06811.1 - 4.5e-08 33.1 10.5 0.15 12.4 0.1 6.9 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.6 CBY06811.1 - 4.9e-05 23.2 18.5 0.42 10.6 0.0 7.4 8 0 0 8 8 8 2 Kelch motif Kelch_2 PF07646.15 CBY06811.1 - 8.3e-05 22.4 11.8 0.83 9.7 0.0 7.5 7 0 0 7 7 7 1 Kelch motif Kelch_1 PF01344.25 CBY06811.1 - 0.0059 16.2 8.4 0.36 10.4 0.0 5.7 7 0 0 7 7 7 1 Kelch motif Mucin PF01456.17 CBY06811.1 - 0.17 11.9 19.3 0.4 10.7 19.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Kelch_4 PF13418.6 CBY06811.1 - 2.2 8.4 22.5 1 9.5 0.3 6.7 8 0 0 8 8 8 0 Galactose oxidase, central domain SLC12 PF03522.15 CBY06812.1 - 5.8e-13 48.7 0.0 6.4e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Solute carrier family 12 OrsD PF12013.8 CBY06813.1 - 0.00047 20.6 1.4 0.09 13.2 0.2 1.6 1 1 1 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1059 PF06348.11 CBY06813.1 - 0.0032 17.7 0.0 0.0068 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) zf-C2H2 PF00096.26 CBY06813.1 - 0.0036 17.7 0.2 0.0079 16.6 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type Actin_micro PF17003.5 CBY06813.1 - 0.0056 15.9 0.1 0.0087 15.3 0.1 1.2 1 0 0 1 1 1 1 Putative actin-like family zf-C2H2_4 PF13894.6 CBY06813.1 - 0.0065 17.2 0.3 0.013 16.2 0.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY06813.1 - 0.013 15.3 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_12 PF18658.1 CBY06813.1 - 0.086 12.4 0.3 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 CBY06814.1 - 1.5e-05 25.4 7.7 0.0042 17.8 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY06814.1 - 0.0083 16.5 14.2 0.12 12.9 0.7 3.8 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf_UBZ PF18439.1 CBY06814.1 - 0.015 14.9 0.5 0.077 12.6 0.1 2.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-CCHC_5 PF14787.6 CBY06814.1 - 0.2 11.4 0.3 0.2 11.4 0.3 3.1 3 1 0 3 3 3 0 GAG-polyprotein viral zinc-finger DUF1610 PF07754.11 CBY06814.1 - 0.2 11.6 7.7 0.17 11.9 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-CHY PF05495.12 CBY06814.1 - 0.28 11.7 5.6 7.8 7.1 0.5 2.2 2 0 0 2 2 2 0 CHY zinc finger zf-Di19 PF05605.12 CBY06814.1 - 0.52 10.7 6.8 0.47 10.8 3.5 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CBY06814.1 - 2.5 8.7 0.0 2.5 8.7 0.0 3.9 3 2 0 3 3 3 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 CBY06814.1 - 8.5 6.4 8.6 91 3.1 8.6 2.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain OrsD PF12013.8 CBY06815.1 - 0.00045 20.6 1.1 0.072 13.5 0.1 1.6 1 1 1 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1059 PF06348.11 CBY06815.1 - 0.0034 17.6 0.3 0.0093 16.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1059) zf-C2H2 PF00096.26 CBY06815.1 - 0.0042 17.5 0.2 0.01 16.3 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type Actin_micro PF17003.5 CBY06815.1 - 0.0074 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative actin-like family zf-C2H2_4 PF13894.6 CBY06815.1 - 0.0078 17.0 0.3 0.017 15.9 0.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY06815.1 - 0.016 15.0 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_12 PF18658.1 CBY06815.1 - 0.12 12.0 0.3 0.22 11.1 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type DUF5618 PF18498.1 CBY06816.1 - 0.0032 17.6 0.4 0.0043 17.2 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5618) BORCS7 PF16088.5 CBY06816.1 - 0.091 13.0 3.3 0.21 11.9 3.1 1.7 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 FAM76 PF16046.5 CBY06816.1 - 0.87 8.9 9.5 2.3 7.5 9.5 1.7 1 1 0 1 1 1 0 FAM76 protein Csm1_N PF18504.1 CBY06816.1 - 4.6 7.7 9.9 1.7 9.0 0.6 2.7 2 1 1 3 3 3 0 Csm1 N-terminal domain VWA PF00092.28 CBY06817.1 - 5.3e-45 153.8 0.0 7.2e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY06817.1 - 6.2e-19 68.6 0.0 1e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY06817.1 - 1.9e-05 24.7 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.21 CBY06817.1 - 0.0025 18.1 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Sushi PF00084.20 CBY06818.1 - 9.2e-39 131.9 47.6 2e-09 37.9 3.9 6.1 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) cEGF PF12662.7 CBY06818.1 - 4.8 7.2 25.2 3 7.9 1.4 4.6 4 0 0 4 4 4 0 Complement Clr-like EGF-like Sushi PF00084.20 CBY06819.1 - 1.6e-61 204.8 84.8 9e-11 42.2 7.0 9.7 9 1 1 10 10 10 8 Sushi repeat (SCR repeat) mono-CXXC PF15626.6 CBY06819.1 - 3.7 8.0 13.1 49 4.4 0.0 5.0 4 0 0 4 4 4 0 single CXXC unit VWA PF00092.28 CBY06820.1 - 1.6e-48 165.3 0.0 2.1e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY06820.1 - 2.4e-17 63.5 0.0 3.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sushi PF00084.20 CBY06820.1 - 3.4e-06 27.6 12.8 0.0016 19.0 4.3 2.7 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Collagen PF01391.18 CBY06820.1 - 0.0062 16.3 10.8 0.011 15.4 10.8 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Legionella_OMP PF05150.12 CBY06820.1 - 0.086 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor HRM PF02793.22 CBY06820.1 - 0.091 13.1 12.0 1.5 9.2 4.9 2.5 2 0 0 2 2 2 0 Hormone receptor domain TSP_1 PF00090.19 CBY06821.1 - 1.4e-11 44.4 25.7 1.1e-07 31.9 10.5 6.2 8 0 0 8 8 8 2 Thrombospondin type 1 domain FXa_inhibition PF14670.6 CBY06821.1 - 2.1e-11 43.9 35.8 5e-10 39.5 9.7 7.6 6 1 1 7 7 7 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CBY06821.1 - 2.7e-07 30.7 10.9 2.7e-07 30.7 10.9 7.6 8 1 0 8 8 8 3 Calcium-binding EGF domain cEGF PF12662.7 CBY06821.1 - 0.0013 18.6 1.0 0.0013 18.6 1.0 6.2 6 0 0 6 6 6 3 Complement Clr-like EGF-like Lectin_C PF00059.21 CBY06822.1 - 3.9e-07 30.8 0.7 0.00016 22.4 0.0 2.4 2 0 0 2 2 2 2 Lectin C-type domain DUF2202 PF09968.9 CBY06822.1 - 0.11 12.4 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) Ion_trans_2 PF07885.16 CBY06823.1 - 6.5e-14 51.7 9.4 6.6e-10 38.8 3.3 2.6 2 0 0 2 2 2 2 Ion channel Phospholip_A2_1 PF00068.19 CBY06823.1 - 7e-14 52.3 3.5 7e-14 52.3 3.5 1.8 2 0 0 2 2 2 1 Phospholipase A2 DUF3310 PF11753.8 CBY06823.1 - 0.076 13.2 0.3 0.2 11.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) An_peroxidase PF03098.15 CBY06825.1 - 5.1e-51 173.8 0.0 6.1e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Mucin2_WxxW PF13330.6 CBY06826.1 - 2.3e-39 134.1 1.8 1.4e-17 64.3 0.0 4.2 5 0 0 5 5 5 2 Mucin-2 protein WxxW repeating region An_peroxidase PF03098.15 CBY06826.1 - 2.5e-31 108.9 0.0 2.2e-30 105.8 0.0 2.0 2 0 0 2 2 2 1 Animal haem peroxidase Kelch_2 PF07646.15 CBY06828.1 - 0.022 14.8 0.2 2.6 8.2 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY06828.1 - 0.049 13.6 0.1 13 5.9 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY06828.1 - 1.1 9.7 5.0 3.1 8.2 0.0 3.2 2 1 1 3 3 3 0 Kelch motif Piezo_RRas_bdg PF12166.8 CBY06829.1 - 1.8e-69 235.1 0.1 1.8e-69 235.1 0.1 1.4 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain An_peroxidase PF03098.15 CBY06830.1 - 2.4e-86 290.4 0.0 1.3e-85 288.0 0.0 1.9 2 0 0 2 2 2 1 Animal haem peroxidase Mucin2_WxxW PF13330.6 CBY06830.1 - 1.1e-38 131.9 2.4 1.8e-17 64.0 0.0 4.1 5 0 0 5 5 5 2 Mucin-2 protein WxxW repeating region Piezo_RRas_bdg PF12166.8 CBY06831.1 - 6.7e-38 131.1 0.1 7.8e-38 130.8 0.1 1.0 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain EGF_3 PF12947.7 CBY06834.1 - 7.1e-39 131.7 307.5 1.8e-09 37.6 13.1 19.0 17 1 1 18 18 18 11 EGF domain EGF_CA PF07645.15 CBY06834.1 - 1.5e-13 50.7 81.4 1e-05 25.7 11.4 20.4 14 5 6 20 20 20 8 Calcium-binding EGF domain EGF PF00008.27 CBY06834.1 - 4.8e-09 36.3 275.4 0.0042 17.4 5.1 21.1 18 3 4 22 22 22 12 EGF-like domain cEGF PF12662.7 CBY06834.1 - 0.0032 17.3 8.6 0.0099 15.8 1.9 19.3 18 2 0 18 18 18 12 Complement Clr-like EGF-like Peptidase_M1 PF01433.20 CBY06835.1 - 8e-53 179.2 0.1 1.4e-52 178.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY06835.1 - 2.8e-38 132.0 1.4 5.1e-38 131.1 1.4 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CBY06835.1 - 0.00025 20.7 0.1 0.00051 19.7 0.1 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain ERAP1_C PF11838.8 CBY06836.1 - 2.9e-32 112.5 1.8 3.5e-32 112.2 1.8 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF413 PF04219.12 CBY06836.1 - 0.016 15.2 0.1 0.68 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF Fib_alpha PF08702.10 CBY06838.1 - 0.0032 17.7 0.0 0.0038 17.4 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Na_Ca_ex PF01699.24 CBY06839.1 - 2.1e-26 92.7 13.0 3.2e-26 92.1 13.0 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Phage_holin_3_6 PF07332.11 CBY06839.1 - 0.49 10.5 16.0 16 5.6 12.4 2.9 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Na_Ca_ex PF01699.24 CBY06840.1 - 3.6e-25 88.7 12.7 3.6e-25 88.7 12.7 1.8 2 0 0 2 2 2 1 Sodium/calcium exchanger protein YdjM PF04307.14 CBY06840.1 - 0.12 11.7 3.8 0.088 12.1 1.2 1.9 2 0 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase YtpI PF14007.6 CBY06840.1 - 0.82 9.8 7.9 0.45 10.7 0.9 2.3 2 0 0 2 2 2 0 YtpI-like protein DUF4131 PF13567.6 CBY06840.1 - 4.1 7.0 7.2 1.6 8.3 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3810 PF12725.7 CBY06840.1 - 5.1 6.3 11.3 7.5 5.8 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF373 PF04123.13 CBY06840.1 - 6 6.2 8.1 5.7 6.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DPM2 PF07297.12 CBY06840.1 - 9.4 6.6 11.2 1.4 9.3 2.2 3.0 3 0 0 3 3 3 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Kelch_6 PF13964.6 CBY06842.1 - 0.0043 17.3 5.3 0.038 14.3 0.1 3.7 4 1 1 5 5 5 1 Kelch motif Kelch_2 PF07646.15 CBY06842.1 - 0.25 11.4 5.5 11 6.2 0.1 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.6 CBY06842.1 - 0.45 10.9 2.6 1.3 9.4 0.3 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Pkinase PF00069.25 CBY06843.1 - 1.2e-08 34.7 1.3 2.1e-08 33.9 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY06843.1 - 6.4e-06 25.6 0.1 9.9e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CUB PF00431.20 CBY06844.1 - 0.00018 21.8 0.1 0.00026 21.3 0.1 1.2 1 0 0 1 1 1 1 CUB domain RT_RNaseH_2 PF17919.1 CBY06846.1 - 9.1e-25 86.6 0.0 3e-24 85.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY06846.1 - 5.1e-16 58.9 0.0 5.1e-16 58.9 0.0 2.3 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CBY06846.1 - 3.4e-14 53.0 0.0 8e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY06846.1 - 4.7e-09 36.2 0.0 9.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DNA_pol_viral_C PF00336.18 CBY06846.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain zf-H2C2 PF09337.10 CBY06846.1 - 0.0054 16.9 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Lactamase_B_6 PF16661.5 CBY06846.1 - 0.038 13.4 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CBY06846.1 - 0.12 12.3 0.7 2.8 7.9 0.1 2.7 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Tetraspanin PF00335.20 CBY06847.1 - 3.3 7.4 13.0 0.4 10.3 6.1 2.0 1 1 0 2 2 2 0 Tetraspanin family ATP_synt_H PF05493.13 CBY06847.1 - 5.7 7.5 8.7 20 5.7 4.3 2.8 1 1 1 2 2 2 0 ATP synthase subunit H adh_short_C2 PF13561.6 CBY06848.1 - 9.1e-50 169.4 0.1 1.1e-49 169.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY06848.1 - 4.5e-31 107.8 0.0 5.6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY06848.1 - 6.4e-06 26.2 1.0 5.7e-05 23.1 1.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY06848.1 - 0.0095 15.4 0.0 0.025 14.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBY06848.1 - 0.031 14.1 0.0 0.044 13.7 0.0 1.3 1 1 0 1 1 1 0 NAD(P)H-binding Kinesin PF00225.23 CBY06849.1 - 0.00079 18.4 0.1 0.00079 18.4 0.1 1.8 2 1 0 2 2 2 1 Kinesin motor domain ARGLU PF15346.6 CBY06849.1 - 0.021 14.7 12.9 0.029 14.3 12.9 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 QueC PF06508.13 CBY06849.1 - 0.13 11.7 0.2 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC FapA PF03961.13 CBY06849.1 - 0.19 10.3 8.9 0.21 10.2 8.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5340 PF17275.2 CBY06849.1 - 0.25 11.5 5.0 0.42 10.8 1.6 2.5 1 1 2 3 3 3 0 Family of unknown function (DUF5340) OmpH PF03938.14 CBY06849.1 - 0.29 11.5 12.0 0.48 10.8 12.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec5 PF15469.6 CBY06849.1 - 0.49 10.2 9.7 0.34 10.7 7.4 1.8 1 1 1 2 2 2 0 Exocyst complex component Sec5 Exonuc_VII_L PF02601.15 CBY06849.1 - 1.3 8.6 7.7 1.4 8.4 7.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit XkdW PF09636.10 CBY06849.1 - 6.3 6.9 12.6 0.96 9.6 5.7 2.1 1 1 1 2 2 2 0 XkdW protein Med21 PF11221.8 CBY06849.1 - 7.9 6.7 13.3 0.53 10.5 1.3 2.5 1 1 0 2 2 2 0 Subunit 21 of Mediator complex Kinesin PF00225.23 CBY06851.1 - 3.4e-39 134.7 0.6 4.1e-39 134.4 0.6 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY06851.1 - 5.7e-17 62.0 0.5 1.4e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding DUF799 PF05643.11 CBY06851.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) RVT_1 PF00078.27 CBY06852.1 - 4.7e-17 62.2 0.1 6.7e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrin_beta PF00362.18 CBY06853.1 - 1.7e-46 158.9 0.1 3.2e-46 158.0 0.1 1.4 1 0 0 1 1 1 1 Integrin beta chain VWA domain EGF_2 PF07974.13 CBY06853.1 - 0.00011 22.4 12.3 0.00011 22.4 12.3 6.9 4 3 2 6 6 6 2 EGF-like domain PBD PF00786.28 CBY06855.1 - 0.15 12.4 0.2 0.62 10.5 0.1 1.9 2 0 0 2 2 2 0 P21-Rho-binding domain CUB PF00431.20 CBY06856.1 - 1.3e-10 41.5 0.0 1.5e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 CUB domain Spore_III_AB PF09548.10 CBY06857.1 - 0.25 11.4 0.0 0.25 11.4 0.0 2.9 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) Pox_A14 PF05767.12 CBY06857.1 - 1.6 8.9 7.9 0.14 12.4 0.6 2.6 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 GIY-YIG PF01541.24 CBY06859.1 - 0.003 17.8 0.4 0.0099 16.1 0.2 2.1 1 1 1 2 2 2 1 GIY-YIG catalytic domain Rootletin PF15035.6 CBY06859.1 - 0.013 15.5 3.9 0.013 15.5 3.9 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.6 CBY06859.1 - 0.014 15.3 5.1 0.014 15.3 5.1 2.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH THUMP PF02926.17 CBY06859.1 - 0.015 15.4 0.1 0.036 14.2 0.1 1.6 1 0 0 1 1 1 0 THUMP domain TORC_N PF12884.7 CBY06859.1 - 0.27 12.0 3.2 4 8.3 0.3 2.7 3 0 0 3 3 3 0 Transducer of regulated CREB activity, N terminus ZapB PF06005.12 CBY06859.1 - 8.8 6.9 12.9 0.62 10.5 4.7 3.0 2 2 1 3 3 3 0 Cell division protein ZapB Aa_trans PF01490.18 CBY06860.1 - 5.6e-76 255.9 23.5 6.4e-76 255.7 23.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MARVEL PF01284.23 CBY06860.1 - 0.0089 16.1 1.5 0.0089 16.1 1.5 3.3 2 2 2 4 4 4 1 Membrane-associating domain Phospholamban PF04272.14 CBY06860.1 - 0.42 10.1 6.8 0.38 10.3 0.2 3.5 3 0 0 3 3 3 0 Phospholamban Deltameth_res PF16020.5 CBY06860.1 - 7.5 6.5 9.2 23 5.0 0.5 3.7 3 1 1 4 4 4 0 Deltamethrin resistance EF-hand_7 PF13499.6 CBY06861.1 - 1.1e-31 109.1 23.1 9.1e-07 29.2 2.4 6.4 6 0 0 6 6 6 6 EF-hand domain pair EF-hand_6 PF13405.6 CBY06861.1 - 1.3e-19 68.4 15.4 0.00015 21.4 0.4 9.5 9 1 1 10 10 10 6 EF-hand domain EF-hand_11 PF08976.11 CBY06861.1 - 7.3e-17 62.1 10.5 1.7e-07 32.1 0.1 5.9 6 0 0 6 6 6 4 EF-hand domain EF-hand_1 PF00036.32 CBY06861.1 - 5e-14 50.7 12.2 0.13 11.9 0.0 8.7 10 0 0 10 10 10 4 EF hand EF-hand_8 PF13833.6 CBY06861.1 - 1.3e-12 47.4 10.9 0.00023 21.0 0.3 7.6 7 2 1 8 8 8 4 EF-hand domain pair EF-hand_9 PF14658.6 CBY06861.1 - 4.4e-07 30.1 1.5 0.027 14.8 0.0 5.2 5 2 1 6 6 6 2 EF-hand domain DUF5580 PF17743.1 CBY06861.1 - 5e-07 28.6 1.8 0.019 13.5 0.0 3.9 2 2 1 3 3 3 3 Family of unknown function (DUF5580) HTH_33 PF13592.6 CBY06861.1 - 0.0011 18.6 0.0 2.2 8.0 0.0 3.8 3 0 0 3 3 3 1 Winged helix-turn helix Phospholip_A2_1 PF00068.19 CBY06863.1 - 6.5e-15 55.6 7.5 6.5e-15 55.6 7.5 2.2 2 0 0 2 2 2 1 Phospholipase A2 3HCDH_N PF02737.18 CBY06864.1 - 2.7e-42 144.7 0.0 5.4e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CBY06864.1 - 4.1e-15 56.2 0.0 1.2e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBY06864.1 - 1.2e-06 28.8 0.0 2.6e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 CBY06864.1 - 3.3e-06 26.8 0.2 6e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 CBY06864.1 - 0.00013 21.4 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 CBY06864.1 - 0.011 15.8 0.1 0.023 14.8 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CBY06864.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CBY06864.1 - 0.015 15.8 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 CBY06864.1 - 0.015 15.8 0.1 0.033 14.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 CBY06864.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 CBY06864.1 - 0.03 13.6 0.1 0.06 12.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY06864.1 - 0.074 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 CBY06864.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 CBY06864.1 - 0.077 13.6 0.4 0.22 12.2 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Phospholip_A2_1 PF00068.19 CBY06865.1 - 2.3e-14 53.8 4.9 6.3e-14 52.4 4.9 1.7 1 0 0 1 1 1 1 Phospholipase A2 Cu2_monoox_C PF03712.15 CBY06867.1 - 1.3e-23 83.3 0.0 2.4e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain SAM_2 PF07647.17 CBY06868.1 - 2.6e-16 59.5 0.3 8.8e-10 38.6 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY06868.1 - 2.5e-12 47.0 0.5 0.00019 21.8 0.0 3.2 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 CBY06868.1 - 0.01 15.6 0.1 0.09 12.6 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Erf4 PF10256.9 CBY06869.1 - 0.095 12.8 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family ADK PF00406.22 CBY06870.1 - 7.7e-54 181.9 0.1 9.1e-54 181.7 0.1 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBY06870.1 - 3.3e-36 124.7 0.2 4.6e-36 124.2 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBY06870.1 - 8.6e-10 38.9 0.0 1.4e-09 38.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY06870.1 - 6.8e-09 36.4 0.0 9e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CBY06870.1 - 0.0051 16.5 0.1 2.9 7.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase CoaE PF01121.20 CBY06870.1 - 0.0084 15.8 0.2 4.1 7.0 0.0 2.2 2 0 0 2 2 2 2 Dephospho-CoA kinase Zeta_toxin PF06414.12 CBY06870.1 - 0.011 15.0 0.5 0.038 13.3 0.5 1.8 1 1 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 CBY06870.1 - 0.023 15.0 0.2 0.04 14.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CBY06870.1 - 0.031 14.0 0.5 0.23 11.2 0.0 2.0 1 1 1 2 2 2 0 Cytidylate kinase Ploopntkinase3 PF18751.1 CBY06870.1 - 0.044 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 CBY06870.1 - 0.045 14.0 0.0 0.099 12.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBY06870.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain PAS_7 PF12860.7 CBY06870.1 - 0.071 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 PAS fold dNK PF01712.19 CBY06870.1 - 0.13 12.1 0.1 0.44 10.4 0.0 1.9 2 1 0 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 CBY06871.1 - 5.6e-72 240.7 0.1 4.4e-35 121.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBY06871.1 - 2e-55 188.4 16.8 3.4e-43 148.3 10.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CBY06871.1 - 1.6e-16 60.4 2.3 1.8e-06 27.6 0.0 3.9 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CBY06871.1 - 4.4e-10 40.0 1.7 0.00082 19.7 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBY06871.1 - 7.9e-09 36.1 1.0 0.00072 20.0 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CBY06871.1 - 1.1e-07 31.1 0.2 0.0035 16.2 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 CBY06871.1 - 1.7e-07 31.3 0.2 0.018 14.9 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CBY06871.1 - 1.8e-07 30.7 0.0 0.014 14.6 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_29 PF13555.6 CBY06871.1 - 1e-06 28.4 0.3 0.055 13.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CBY06871.1 - 1.9e-06 27.8 4.2 0.019 14.7 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 CBY06871.1 - 1.5e-05 24.8 0.2 0.29 10.8 0.1 3.4 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CBY06871.1 - 2.6e-05 23.6 1.3 0.21 10.9 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA PF00004.29 CBY06871.1 - 3.8e-05 24.1 0.4 2.3 8.7 0.0 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 CBY06871.1 - 8.1e-05 22.8 5.1 0.5 10.6 0.3 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 CBY06871.1 - 0.0001 21.9 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 CBY06871.1 - 0.001 19.1 0.6 1.1 9.3 0.0 3.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBY06871.1 - 0.0011 19.3 0.0 2.4 8.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 CBY06871.1 - 0.0015 17.7 0.1 0.45 9.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 CBY06871.1 - 0.0021 18.6 5.3 5.7 7.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 CBY06871.1 - 0.0023 17.6 0.4 0.17 11.5 0.0 2.7 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 CBY06871.1 - 0.0027 17.5 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 CBY06871.1 - 0.005 16.8 0.1 3.7 7.4 0.0 2.8 2 0 0 2 2 2 1 NTPase AAA_21 PF13304.6 CBY06871.1 - 0.0051 16.7 0.2 18 5.0 0.1 3.7 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 CBY06871.1 - 0.0061 16.7 1.0 3.1 7.8 0.0 3.5 3 1 0 3 3 3 1 Helicase HerA, central domain NACHT PF05729.12 CBY06871.1 - 0.015 15.2 0.2 4.9 7.0 0.1 2.7 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 CBY06871.1 - 0.015 14.5 0.3 2.4 7.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Rad17 PF03215.15 CBY06871.1 - 0.018 15.0 8.2 0.25 11.2 0.3 3.2 3 2 0 3 3 2 0 Rad17 P-loop domain AAA_24 PF13479.6 CBY06871.1 - 0.026 14.3 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CBY06871.1 - 0.039 12.9 0.0 5.6 5.9 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 CBY06871.1 - 0.04 13.7 2.4 27 4.5 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 CBY06871.1 - 0.047 13.0 0.1 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 CBY06871.1 - 0.078 12.7 1.4 6.3 6.5 0.1 3.0 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 CBY06871.1 - 0.093 13.3 0.0 19 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CBY06871.1 - 0.098 12.5 0.1 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 CBY06871.1 - 0.1 12.7 0.2 12 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 CBY06871.1 - 0.11 12.8 0.1 22 5.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CBY06871.1 - 0.15 12.0 0.1 29 4.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CBY06871.1 - 0.17 11.4 0.1 14 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CBY06871.1 - 0.63 9.3 2.8 21 4.3 0.0 2.9 3 0 0 3 3 3 0 Septin Glyco_transf_10 PF00852.19 CBY06873.1 - 7.8e-49 165.8 0.5 1.3e-48 165.0 0.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY06873.1 - 4.6e-14 52.8 0.0 1.1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Leader_CPA1 PF08252.11 CBY06873.1 - 0.079 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide Pyridoxal_deC PF00282.19 CBY06874.1 - 7e-20 71.1 0.0 1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CBY06874.1 - 0.00031 19.8 0.0 0.00066 18.7 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBY06874.1 - 0.0011 18.4 0.0 0.0025 17.2 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CBY06874.1 - 0.0014 17.2 0.0 0.0023 16.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SepSecS PF05889.13 CBY06874.1 - 0.0017 17.1 0.1 0.0043 15.8 0.0 1.6 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS HisKA_7TM PF16927.5 CBY06875.1 - 0.0049 16.9 0.5 0.14 12.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal 7TM region of histidine kinase PIRT PF15099.6 CBY06875.1 - 0.075 12.6 0.2 7.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Neurensin PF14927.6 CBY06875.1 - 0.13 12.0 0.0 9.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Neurensin Sulfotransfer_4 PF17784.1 CBY06876.1 - 1.6e-51 175.2 0.2 1.9e-51 174.9 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY06876.1 - 0.0087 16.5 0.1 0.018 15.4 0.0 1.6 1 1 1 2 2 2 1 Sulfotransferase family DtxR PF18357.1 CBY06876.1 - 0.25 11.0 0.1 0.25 11.0 0.1 2.0 3 0 0 3 3 3 0 Diphteria toxin repressor SH3 domain zf-C4 PF00105.18 CBY06877.1 - 3.4e-28 97.9 14.5 1.1e-27 96.3 14.5 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Helicase_C PF00271.31 CBY06877.1 - 0.16 12.3 1.0 0.84 10.0 0.1 2.3 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Zona_pellucida PF00100.23 CBY06878.1 - 3.3e-40 138.5 0.1 4.2e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Ctr PF04145.15 CBY06878.1 - 0.00017 22.3 2.1 0.00017 22.3 2.1 1.7 2 0 0 2 2 2 1 Ctr copper transporter family zf-H2C2_5 PF13909.6 CBY06879.1 - 7.1e-09 35.3 8.2 2.9e-07 30.1 3.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CBY06879.1 - 2.2e-08 34.1 14.0 0.00076 19.8 2.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY06879.1 - 1.3e-05 25.4 18.7 1.7e-05 25.1 2.6 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY06879.1 - 0.00012 22.6 16.6 0.025 15.4 1.6 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBY06879.1 - 0.01 16.1 5.3 2.4 8.5 0.7 2.6 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 CBY06879.1 - 0.037 13.9 0.8 0.58 10.1 0.0 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2_2 PF12756.7 CBY06879.1 - 0.067 13.5 7.8 2.3 8.6 1.1 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CBY06879.1 - 0.35 11.3 2.9 0.77 10.2 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CBY06879.1 - 5.9 7.1 6.4 35 4.6 2.2 3.3 2 1 1 3 3 3 0 Zinc ribbon domain zf-C3HC4_2 PF13923.6 CBY06880.1 - 1e-05 25.3 12.5 1e-05 25.3 12.5 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY06880.1 - 4e-05 23.8 11.8 4e-05 23.8 11.8 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY06880.1 - 8.7e-05 22.3 13.5 8.7e-05 22.3 13.5 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.11 CBY06880.1 - 0.0075 16.1 7.3 4.1 7.3 2.7 3.3 3 0 0 3 3 3 1 GAGA factor zf-RING_5 PF14634.6 CBY06880.1 - 0.022 14.7 5.6 0.022 14.7 5.6 3.4 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY06880.1 - 0.023 14.6 13.4 0.023 14.6 13.4 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RNF220 PF15926.5 CBY06880.1 - 0.073 12.7 0.2 0.073 12.7 0.2 2.3 2 1 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf-RING_6 PF14835.6 CBY06880.1 - 0.14 12.0 7.6 0.37 10.7 7.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 CBY06880.1 - 2 8.5 13.3 9 6.4 13.3 2.2 1 0 0 1 1 1 0 RING-type zinc-finger FLYWCH PF04500.16 CBY06881.1 - 0.16 12.1 0.3 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 FLYWCH zinc finger domain MFS_1 PF07690.16 CBY06882.1 - 4.1e-13 49.0 0.4 4.3e-13 48.9 0.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.9 CBY06882.1 - 0.0055 16.9 0.2 0.01 16.0 0.2 1.4 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2207 PF09972.9 CBY06882.1 - 0.023 13.4 0.3 0.029 13.1 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Zona_pellucida PF00100.23 CBY06883.1 - 4.4e-11 43.1 0.8 5.7e-11 42.7 0.8 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain CBM_14 PF01607.24 CBY06883.1 - 0.056 13.6 1.3 0.17 12.1 1.3 1.8 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain DUF5374 PF17344.2 CBY06883.1 - 0.75 9.8 0.1 0.75 9.8 0.1 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF5374) CUB PF00431.20 CBY06884.1 - 6.3e-19 68.3 0.0 1.5e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 CUB domain MAM PF00629.23 CBY06884.1 - 1.2e-15 57.7 0.2 2.5e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Sushi PF00084.20 CBY06884.1 - 0.11 13.1 8.5 0.19 12.3 0.9 2.8 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Aminotran_5 PF00266.19 CBY06885.1 - 2.3e-49 168.3 0.0 2.7e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CBY06885.1 - 2.8e-05 22.8 0.0 3.6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CBY06885.1 - 0.035 13.3 0.0 0.49 9.5 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II CoA_binding_2 PF13380.6 CBY06885.1 - 0.084 13.4 0.0 0.29 11.7 0.1 1.7 2 0 0 2 2 2 0 CoA binding domain zf-rbx1 PF12678.7 CBY06886.1 - 1.4e-25 89.3 16.0 2e-25 88.8 16.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY06886.1 - 4.7e-18 65.0 11.8 6e-18 64.7 11.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBY06886.1 - 3.8e-07 30.3 18.4 1.7e-05 25.1 18.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY06886.1 - 0.00017 21.4 15.1 0.0033 17.3 15.1 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY06886.1 - 0.00054 19.7 18.3 0.00098 18.9 12.8 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY06886.1 - 0.0017 18.2 14.5 0.0074 16.1 8.3 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY06886.1 - 0.42 10.4 16.7 53 3.7 16.7 2.7 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 CBY06886.1 - 0.45 10.5 15.3 2.8 8.0 15.3 2.4 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 CBY06886.1 - 0.62 10.3 13.5 7.3 6.8 13.7 2.6 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CBY06886.1 - 0.88 9.6 9.9 1.9 8.6 8.5 2.3 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CBY06886.1 - 1.3 8.7 18.5 0.083 12.5 5.9 2.6 1 1 2 3 3 3 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 CBY06886.1 - 2 8.8 15.0 20 5.6 15.0 2.3 1 1 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 CBY06886.1 - 5.4 7.1 11.1 0.22 11.6 4.6 2.1 2 1 0 2 2 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 CBY06886.1 - 7.6 6.8 13.0 0.22 11.7 2.8 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING NopRA1 PF16201.5 CBY06887.1 - 2.6e-22 79.4 1.7 2.6e-22 79.4 1.7 1.9 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 EF-hand_8 PF13833.6 CBY06887.1 - 0.072 12.9 0.1 1.3 8.9 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain pair RMI1_N PF08585.12 CBY06888.1 - 7.8e-13 48.7 4.0 1.9e-09 37.6 0.1 2.7 2 1 1 3 3 3 2 RecQ mediated genome instability protein UBA PF00627.31 CBY06888.1 - 6.5e-08 32.3 0.3 1.2e-07 31.5 0.3 1.4 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 CBY06888.1 - 0.0027 17.7 0.3 0.0063 16.5 0.2 1.6 2 0 0 2 2 2 1 HOIP UBA domain pair DUF4551 PF15087.6 CBY06888.1 - 0.1 11.5 5.6 0.13 11.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-C4 PF00105.18 CBY06891.1 - 6.8e-26 90.5 16.9 1.4e-25 89.5 16.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY06891.1 - 2.2e-08 33.9 8.1 2.2e-08 33.9 8.1 2.1 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Forkhead PF00250.18 CBY06893.1 - 3.6e-38 129.7 0.3 7.3e-38 128.7 0.3 1.5 1 0 0 1 1 1 1 Forkhead domain DUF4820 PF16091.5 CBY06893.1 - 2.2 7.6 4.8 0.95 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) LRR_8 PF13855.6 CBY06894.1 - 8.9e-66 217.5 47.9 3.8e-18 65.0 2.1 6.3 3 2 3 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 CBY06894.1 - 3.6e-29 101.3 11.6 5.7e-12 45.7 1.5 3.3 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY06894.1 - 1e-26 92.5 61.5 9.9e-07 29.0 0.2 9.0 6 3 2 9 9 9 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY06894.1 - 8.8e-10 38.4 27.7 0.00013 21.5 3.3 4.7 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 CBY06894.1 - 1.5e-09 37.0 40.0 1.5 9.7 0.1 13.7 14 1 0 14 14 14 4 Leucine Rich Repeat Beta_helix PF13229.6 CBY06894.1 - 3.9 7.3 5.6 28 4.5 0.6 3.3 2 1 0 2 2 2 0 Right handed beta helix region LRR_6 PF13516.6 CBY06894.1 - 4.8 7.5 0.0 2.1 8.6 0.0 12.7 15 0 0 15 15 15 0 Leucine Rich repeat Glyco_transf_7N PF13733.6 CBY06895.1 - 7.8e-55 184.2 0.2 1.4e-54 183.4 0.2 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY06895.1 - 1.3e-29 101.6 0.1 2.7e-29 100.7 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY06895.1 - 0.00086 18.9 0.1 0.0021 17.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 AAA_24 PF13479.6 CBY06895.1 - 0.088 12.5 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain ARA70 PF12489.8 CBY06896.1 - 0.0054 16.9 1.8 0.0073 16.5 1.8 1.2 1 0 0 1 1 1 1 Nuclear coactivator TMPIT PF07851.13 CBY06896.1 - 1.4 8.1 6.9 1.5 8.0 6.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein SNARE PF05739.19 CBY06896.1 - 6.5 6.8 7.1 0.93 9.5 0.2 2.5 2 0 0 2 2 2 0 SNARE domain UFD1 PF03152.14 CBY06898.1 - 8.3e-72 240.3 0.0 1e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 CBY06898.1 - 4.2e-05 23.2 0.0 0.00043 20.0 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Mitofilin PF09731.9 CBY06899.1 - 1.8e-42 146.1 56.9 2.1e-42 145.8 55.8 1.6 1 1 0 1 1 1 1 Mitochondrial inner membrane protein YodL PF14191.6 CBY06899.1 - 0.045 14.6 0.1 0.16 12.8 0.1 1.9 1 0 0 1 1 1 0 YodL-like SPOUT_MTase PF02590.17 CBY06899.1 - 1 9.4 9.9 0.11 12.5 4.1 2.3 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase Endotoxin_N PF03945.14 CBY06899.1 - 8.1 6.1 5.9 31 4.2 0.4 2.6 2 1 0 2 2 2 0 delta endotoxin, N-terminal domain FYVE_2 PF02318.16 CBY06902.1 - 4e-06 27.0 12.9 4e-06 27.0 12.9 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger sCache_like PF16736.5 CBY06902.1 - 0.4 10.8 7.2 0.45 10.6 1.7 2.5 2 0 0 2 2 2 0 Single Cache-like UBD PF16455.5 CBY06903.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding domain EGF PF00008.27 CBY06904.1 - 9.7e-12 45.0 76.9 1.8e-05 24.9 9.3 6.7 7 0 0 7 7 7 5 EGF-like domain hEGF PF12661.7 CBY06904.1 - 0.00042 20.8 60.4 0.31 11.8 6.8 7.4 6 0 0 6 6 6 5 Human growth factor-like EGF EGF_2 PF07974.13 CBY06904.1 - 0.028 14.8 72.5 0.08 13.3 9.4 6.8 5 1 1 6 6 6 0 EGF-like domain INTS5_N PF14837.6 CBY06904.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus SOG2 PF10428.9 CBY06904.1 - 0.29 10.3 10.0 0.39 9.9 10.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmod_Pvs28 PF06247.11 CBY06904.1 - 0.56 10.5 34.0 0.18 12.1 3.3 4.5 4 0 0 4 4 4 0 Pvs28 EGF domain Ank_2 PF12796.7 CBY06905.1 - 0.05 14.2 0.0 0.064 13.8 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Cytochrom_NNT PF03264.14 CBY06905.1 - 0.055 13.2 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Ank_4 PF13637.6 CBY06905.1 - 0.094 13.3 0.1 0.18 12.4 0.1 1.5 1 1 0 1 1 1 0 Ankyrin repeats (many copies) PSCyt2 PF07583.11 CBY06905.1 - 0.28 11.1 4.1 20 5.0 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1549) GSu_C4xC__C2xCH PF09698.10 CBY06905.1 - 0.65 10.8 4.4 1.4 9.8 4.4 1.6 1 1 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Ank_2 PF12796.7 CBY06906.1 - 2.5e-06 28.0 0.0 4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY06906.1 - 4.4e-06 27.1 0.0 0.00084 19.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY06906.1 - 0.00016 21.9 0.0 0.65 10.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY06906.1 - 0.00048 20.4 0.0 0.065 13.7 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CBY06906.1 - 0.00066 19.9 0.1 0.46 11.2 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat GIT1_C PF12205.8 CBY06908.1 - 0.09 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term CD225 PF04505.12 CBY06909.1 - 0.00064 19.8 1.3 0.0011 19.1 1.3 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Gal-3-0_sulfotr PF06990.11 CBY06911.1 - 2.6e-22 79.3 0.2 1.3e-21 77.0 0.2 1.8 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY06911.1 - 4e-05 23.7 0.2 6e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family EF-hand_1 PF00036.32 CBY06914.1 - 8.9e-08 31.2 1.2 1.1e-07 30.9 0.1 1.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY06914.1 - 7.5e-07 28.6 0.3 2e-06 27.3 0.3 1.8 1 1 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 CBY06914.1 - 1e-06 28.4 0.2 1.3e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 CBY06914.1 - 1.2e-06 28.8 0.1 1.4e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY06914.1 - 6.9e-06 25.3 0.2 1.3e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.7 CBY06914.1 - 0.079 12.9 0.1 0.15 12.1 0.1 1.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand GSHPx PF00255.19 CBY06915.1 - 0.0004 19.9 0.0 0.00047 19.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 CBY06916.1 - 8.4e-22 76.8 0.0 1.8e-21 75.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione peroxidase LCCL PF03815.19 CBY06917.1 - 3.7e-10 39.8 0.0 7.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.25 CBY06917.1 - 2.4e-08 34.1 0.0 5.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Yippee-Mis18 PF03226.14 CBY06919.1 - 1.2e-12 48.0 0.1 1.8e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AlcCBM31 PF11606.8 CBY06919.1 - 0.0051 17.0 0.3 2.1 8.6 0.0 2.9 2 1 1 3 3 3 2 Family 31 carbohydrate binding protein HNH_5 PF14279.6 CBY06919.1 - 0.091 12.6 0.0 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease MFS_1 PF07690.16 CBY06920.1 - 9.6e-30 103.7 32.6 9.4e-23 80.7 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferric_reduct PF01794.19 CBY06920.1 - 3.3 7.8 9.5 0.49 10.5 0.2 2.9 3 1 0 3 3 3 0 Ferric reductase like transmembrane component Baculo_DNA_bind PF04786.12 CBY06921.1 - 0.053 12.9 2.4 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 ssDNA binding protein Pheromone PF08015.11 CBY06921.1 - 1.1 10.3 3.4 1.1 10.3 0.5 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone SH3_9 PF14604.6 CBY06922.1 - 4.1e-12 45.8 0.1 7.7e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain IMD PF08397.11 CBY06922.1 - 3e-10 39.8 16.3 4.3e-10 39.4 16.3 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_1 PF00018.28 CBY06922.1 - 0.00017 21.1 0.0 0.00035 20.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY06922.1 - 0.00069 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GDPD PF03009.17 CBY06922.1 - 0.0022 17.8 2.6 0.0026 17.5 1.9 1.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF3492 PF11997.8 CBY06922.1 - 0.11 12.2 1.3 0.18 11.5 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Cna_B PF05738.13 CBY06922.1 - 0.77 10.3 6.8 1.6 9.3 6.5 1.8 1 1 0 1 1 1 0 Cna protein B-type domain T7SS_ESX_EspC PF10824.8 CBY06922.1 - 2.1 8.9 6.4 0.36 11.3 0.4 2.9 2 2 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm DUF724 PF05266.14 CBY06922.1 - 2.6 7.9 22.8 1.2 8.9 1.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Terminase_4 PF05119.12 CBY06922.1 - 7.8 7.0 12.7 3.4e+03 -1.5 12.7 3.7 1 1 0 1 1 1 0 Phage terminase, small subunit Draxin PF15550.6 CBY06922.1 - 8 6.2 10.9 7.1 6.4 9.8 1.5 1 1 0 1 1 1 0 Draxin Phospholip_A2_1 PF00068.19 CBY06923.1 - 1.1e-11 45.2 14.5 1.1e-11 45.2 14.5 4.8 2 1 1 4 4 4 1 Phospholipase A2 EGF PF00008.27 CBY06923.1 - 3.2e-07 30.5 23.6 4.1e-05 23.8 7.0 5.5 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 CBY06923.1 - 0.0026 18.3 5.5 0.0026 18.3 5.5 6.3 6 1 0 6 6 6 2 Human growth factor-like EGF EGF_2 PF07974.13 CBY06923.1 - 1.2 9.6 70.3 0.062 13.7 10.1 5.8 5 1 0 5 5 5 0 EGF-like domain Hormone_recep PF00104.30 CBY06924.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Mur_ligase_M PF08245.12 CBY06925.1 - 6.5e-07 29.5 0.5 5.2e-05 23.3 0.1 2.7 1 1 1 2 2 2 2 Mur ligase middle domain MerC PF03203.14 CBY06926.1 - 0.0026 18.2 4.0 0.0026 18.2 4.0 2.4 2 1 0 2 2 2 1 MerC mercury resistance protein She9_MDM33 PF05546.11 CBY06926.1 - 0.081 12.7 0.7 0.75 9.6 0.1 2.1 2 0 0 2 2 2 0 She9 / Mdm33 family DUF4381 PF14316.6 CBY06926.1 - 0.51 10.6 3.5 1.2 9.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Lig_chan PF00060.26 CBY06926.1 - 1.4 8.8 9.7 7 6.5 0.9 3.1 2 1 1 3 3 3 0 Ligand-gated ion channel DUF4212 PF13937.6 CBY06926.1 - 9.7 6.6 18.3 0.052 13.9 1.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Folate_rec PF03024.14 CBY06928.1 - 2.2e-12 47.2 17.8 3e-11 43.5 17.8 2.5 1 1 0 1 1 1 1 Folate receptor family Cadherin_C_2 PF16492.5 CBY06928.1 - 1.6 9.5 3.0 4.4 8.1 3.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Sushi PF00084.20 CBY06929.1 - 0.00091 19.8 0.4 0.00091 19.8 0.4 2.7 2 1 0 2 2 2 1 Sushi repeat (SCR repeat) Mucin PF01456.17 CBY06930.1 - 0.0021 18.0 32.7 0.004 17.1 32.7 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein FSA_C PF10479.9 CBY06930.1 - 0.5 8.4 12.1 0.64 8.1 12.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-C2H2_2 PF12756.7 CBY06931.1 - 1e-08 35.4 1.3 0.0011 19.3 0.1 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBY06931.1 - 4.2e-06 27.1 5.2 0.0029 18.3 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 CBY06931.1 - 3.4e-05 24.2 2.8 0.11 13.0 0.1 3.6 3 1 0 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 CBY06931.1 - 4.6e-05 23.6 8.1 9.6e-05 22.6 1.3 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CBY06931.1 - 7.3e-05 22.7 8.1 0.00058 19.8 1.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CBY06931.1 - 8e-05 23.3 0.9 8e-05 23.3 0.9 2.5 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 CBY06931.1 - 0.0014 18.3 3.5 0.37 10.6 0.1 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CBY06931.1 - 0.0089 16.1 1.3 0.2 11.8 0.1 2.5 2 0 0 2 2 2 1 Zinc ribbon domain zf-C2HC_2 PF13913.6 CBY06931.1 - 0.0096 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type PknG_rubred PF16919.5 CBY06931.1 - 0.015 15.5 4.0 9.7 6.4 0.1 3.4 3 0 0 3 3 3 0 Protein kinase G rubredoxin domain zf-C2H2_9 PF16293.5 CBY06931.1 - 0.12 12.3 2.1 14 5.7 0.4 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 CBY06931.1 - 0.36 10.5 1.9 18 5.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Filament PF00038.21 CBY06932.1 - 4.3e-84 282.8 49.3 4.3e-84 282.8 49.3 1.4 2 0 0 2 2 2 1 Intermediate filament protein Baculo_PEP_C PF04513.12 CBY06932.1 - 0.031 14.3 11.9 0.57 10.2 3.8 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 CBY06932.1 - 0.1 11.9 49.3 0.019 14.3 22.0 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Rab5-bind PF09311.11 CBY06932.1 - 0.32 10.3 43.5 0.17 11.3 12.1 3.5 1 1 3 4 4 4 0 Rabaptin-like protein DUF4515 PF14988.6 CBY06932.1 - 0.6 9.9 42.1 0.082 12.7 4.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) Laminin_II PF06009.12 CBY06932.1 - 1.1 9.3 30.9 0.11 12.5 5.4 4.3 1 1 3 4 4 4 0 Laminin Domain II Aminopep PF10023.9 CBY06932.1 - 1.5 8.1 15.0 0.39 10.0 9.7 2.2 1 1 1 2 2 2 0 Putative aminopeptidase TPR_MLP1_2 PF07926.12 CBY06932.1 - 2.3 8.3 50.0 0.079 13.0 7.2 5.6 2 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CBY06932.1 - 2.8 6.8 56.3 0.069 12.0 12.5 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Lectin_N PF03954.14 CBY06932.1 - 9 6.0 14.7 2.8 7.7 2.5 4.0 1 1 2 4 4 4 0 Hepatic lectin, N-terminal domain Filament_head PF04732.14 CBY06934.1 - 0.0042 17.9 1.4 0.0049 17.7 1.4 1.1 1 0 0 1 1 1 1 Intermediate filament head (DNA binding) region RRM_1 PF00076.22 CBY06935.1 - 2.7e-08 33.5 0.0 4.1e-07 29.7 0.1 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY06935.1 - 0.018 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CBY06935.1 - 0.1 12.5 0.2 6.2 6.8 0.1 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif YfhO PF09586.10 CBY06935.1 - 0.2 9.8 5.0 0.25 9.5 5.0 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RAMP4 PF06624.12 CBY06936.1 - 1.8e-23 82.3 0.2 2e-23 82.2 0.2 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 UPF0242 PF06785.11 CBY06937.1 - 0.038 14.1 0.1 0.062 13.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 7TM_GPCR_Srd PF10317.9 CBY06937.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF2207 PF09972.9 CBY06937.1 - 0.13 11.0 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rhodanese PF00581.20 CBY06938.1 - 1.3e-07 32.1 0.0 1.7e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CBM_21 PF03370.13 CBY06940.1 - 3.9e-32 110.8 2.5 6.2e-32 110.1 2.5 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CBY06940.1 - 2.4e-15 56.9 1.6 5.3e-15 55.8 1.6 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) KH_1 PF00013.29 CBY06943.1 - 4.2e-09 36.1 1.4 2.8e-06 27.1 0.5 2.5 2 0 0 2 2 2 2 KH domain DUF4537 PF15057.6 CBY06943.1 - 0.078 13.0 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Asparaginase_2 PF01112.18 CBY06944.1 - 1.1e-75 254.5 0.1 1.5e-75 254.1 0.1 1.0 1 0 0 1 1 1 1 Asparaginase Sugar_tr PF00083.24 CBY06944.1 - 4.3e-06 25.9 8.8 5.9e-06 25.4 8.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY06944.1 - 4.6e-05 22.5 5.8 4.6e-05 22.5 5.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SPC25 PF06703.11 CBY06944.1 - 2.9 7.6 6.0 7.5 6.3 5.2 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_S30 PF01577.16 CBY06945.1 - 0.027 14.1 8.6 0.034 13.8 8.6 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Tim54 PF11711.8 CBY06945.1 - 0.032 13.0 5.9 0.049 12.4 5.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BUD22 PF09073.10 CBY06945.1 - 0.038 13.4 18.4 0.048 13.0 18.4 1.1 1 0 0 1 1 1 0 BUD22 ADP_ribosyl_GH PF03747.14 CBY06945.1 - 0.1 12.3 1.8 0.13 12.0 1.8 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase CDC27 PF09507.10 CBY06945.1 - 0.13 11.6 21.5 0.15 11.4 21.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dynactin_p62 PF05502.13 CBY06945.1 - 0.23 10.2 5.8 0.26 10.0 5.8 1.1 1 0 0 1 1 1 0 Dynactin p62 family SURF2 PF05477.11 CBY06945.1 - 0.24 11.1 11.2 0.29 10.8 11.2 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DNA_pol_phi PF04931.13 CBY06945.1 - 0.25 9.4 16.2 0.3 9.1 16.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 CBY06945.1 - 0.51 9.1 10.5 0.55 8.9 10.5 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CBY06945.1 - 0.59 9.3 5.4 0.65 9.1 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter OAD_gamma PF04277.13 CBY06945.1 - 0.62 10.7 23.5 1.7 9.3 7.9 2.3 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PA26 PF04636.13 CBY06945.1 - 1.1 8.2 6.7 1.2 8.0 6.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) XRN_M PF17846.1 CBY06945.1 - 1.1 8.2 12.6 1.3 7.9 12.6 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF1754 PF08555.10 CBY06945.1 - 1.6 9.6 30.5 1.1 10.2 16.1 2.1 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) RR_TM4-6 PF06459.12 CBY06945.1 - 1.8 8.3 15.9 2.1 8.1 15.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop53 PF07767.11 CBY06945.1 - 1.8 7.8 25.0 2.5 7.4 25.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Roughex PF06020.11 CBY06945.1 - 1.9 7.5 11.0 2.2 7.3 11.0 1.0 1 0 0 1 1 1 0 Drosophila roughex protein FAM176 PF14851.6 CBY06945.1 - 2.1 8.0 16.0 0.23 11.1 5.5 2.0 1 1 1 2 2 2 0 FAM176 family LYRIC PF15686.5 CBY06945.1 - 2.8 7.4 21.8 3.3 7.2 21.8 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family NPAT_C PF15712.5 CBY06945.1 - 4.3 5.9 11.9 5.2 5.6 11.9 1.0 1 0 0 1 1 1 0 NPAT C terminus TMEM51 PF15345.6 CBY06945.1 - 4.4 7.1 9.3 5.4 6.8 2.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 ATP19 PF11022.8 CBY06945.1 - 4.5 7.7 12.4 0.47 10.9 2.4 2.5 1 1 0 2 2 2 0 ATP synthase subunit K DUF4834 PF16118.5 CBY06945.1 - 5.1 8.1 10.5 1.3 10.1 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) ALMT PF11744.8 CBY06945.1 - 5.5 5.7 7.5 6.2 5.5 7.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 CBY06945.1 - 6.8 5.4 11.1 8.3 5.1 11.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1168 PF06658.12 CBY06945.1 - 9.3 6.1 31.5 11 5.8 16.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) Gelsolin PF00626.22 CBY06946.1 - 6e-65 215.1 1.8 1.1e-12 47.7 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat LpqV PF17301.2 CBY06946.1 - 0.12 12.6 0.3 8.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Putative lipoprotein LpqV OppC_N PF12911.7 CBY06948.1 - 1.4 8.9 10.7 5.7 7.0 0.0 3.4 2 1 1 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Troponin PF00992.20 CBY06949.1 - 9.9e-25 87.4 41.4 6e-22 78.4 32.5 2.0 1 1 1 2 2 2 2 Troponin VPS28 PF03997.12 CBY06949.1 - 0.008 15.9 0.8 0.008 15.9 0.8 2.2 2 1 0 2 2 2 1 VPS28 protein Fasciclin PF02469.22 CBY06949.1 - 0.59 10.4 3.5 0.37 11.0 0.3 2.0 2 0 0 2 2 2 0 Fasciclin domain DUF4407 PF14362.6 CBY06949.1 - 1.4 8.2 16.8 1.7 8.0 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 CBY06949.1 - 9.4 4.2 10.9 11 3.9 10.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sod_Cu PF00080.20 CBY06950.1 - 5.3e-30 104.5 0.3 9e-30 103.7 0.3 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) F5_F8_type_C PF00754.25 CBY06951.1 - 4.6e-09 36.5 0.0 5.7e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain Pfk_N PF18468.1 CBY06951.1 - 0.098 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast Zip PF02535.22 CBY06952.1 - 0.00042 19.6 0.6 0.00049 19.4 0.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter GAGA_bind PF06217.12 CBY06952.1 - 0.0084 16.4 7.7 0.0093 16.3 7.7 1.0 1 0 0 1 1 1 1 GAGA binding protein-like family Presenilin PF01080.17 CBY06952.1 - 0.3 9.8 2.9 0.31 9.8 2.9 1.2 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 CBY06952.1 - 0.57 8.6 5.5 0.72 8.3 5.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CIAPIN1 PF05093.13 CBY06952.1 - 5.6 7.5 8.2 1.2 9.7 3.2 2.0 1 1 1 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Eapp_C PF10238.9 CBY06952.1 - 5.9 7.0 10.2 7.1 6.7 9.7 1.4 1 1 0 1 1 1 0 E2F-associated phosphoprotein Ephrin PF00812.17 CBY06953.1 - 8.2e-36 123.0 0.0 1.1e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Ephrin Adeno_E3_CR2 PF02439.15 CBY06953.1 - 0.075 12.8 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.9 CBY06953.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-C4 PF00105.18 CBY06954.1 - 2.2e-29 101.7 17.1 4.5e-29 100.7 17.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY06954.1 - 2.7e-16 59.8 4.6 2.7e-16 59.8 4.6 1.9 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor CBF PF03914.17 CBY06954.1 - 0.041 13.9 0.1 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 CBF/Mak21 family Glyco_hydro_15 PF00723.21 CBY06954.1 - 0.044 12.6 0.0 0.07 11.9 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 15 SbsC_C PF18058.1 CBY06954.1 - 0.2 11.9 2.1 0.76 10.0 0.1 2.4 2 1 0 2 2 2 0 SbsC C-terminal domain PAS_11 PF14598.6 CBY06955.1 - 2.2e-17 63.2 2.6 4e-15 55.9 0.0 2.9 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 CBY06955.1 - 7e-17 61.5 0.0 5e-11 42.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 CBY06955.1 - 1.2e-11 44.6 0.0 1.6e-05 24.9 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CBY06955.1 - 1.3e-08 35.1 0.4 0.00037 20.7 0.0 3.2 3 0 0 3 3 3 2 PAS domain ORC_WH_C PF18137.1 CBY06955.1 - 0.013 15.6 0.6 0.04 14.0 0.6 1.8 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Strep_SA_rep PF06696.11 CBY06955.1 - 0.05 13.6 1.2 0.17 11.9 1.2 2.0 1 0 0 1 1 1 0 Streptococcal surface antigen repeat PAS_4 PF08448.10 CBY06955.1 - 0.11 12.8 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 PAS fold SPAN-X PF07458.12 CBY06955.1 - 0.15 12.5 6.7 0.051 14.0 2.8 2.1 2 0 0 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome DUF2615 PF11027.8 CBY06956.1 - 8.3e-22 77.3 0.1 9.9e-22 77.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) Ac110_PIF PF07280.11 CBY06956.1 - 0.089 12.6 0.1 0.089 12.6 0.1 1.5 2 0 0 2 2 2 0 Per os infectivity factor AC110 Frizzled PF01534.17 CBY06957.1 - 5.6e-22 78.2 0.8 9.2e-22 77.5 0.8 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CBY06957.1 - 5.1e-19 68.9 4.9 5.1e-19 68.9 4.9 2.0 2 0 0 2 2 2 1 Fz domain DUF2678 PF10856.8 CBY06957.1 - 0.0044 16.9 0.5 0.0091 15.9 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF2417 PF10329.9 CBY06957.1 - 0.049 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Frizzled PF01534.17 CBY06958.1 - 1.4e-41 142.6 1.6 1.8e-41 142.3 1.6 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 CBY06958.1 - 0.0018 17.6 0.4 0.0025 17.1 0.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 CBY06958.1 - 0.028 13.6 0.3 0.038 13.1 0.3 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor 7TM_GPCR_Srv PF10323.9 CBY06958.1 - 0.054 12.9 0.1 0.073 12.4 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv PsbH PF00737.20 CBY06959.1 - 2.8 7.8 5.8 22 4.9 0.0 3.0 3 0 0 3 3 3 0 Photosystem II 10 kDa phosphoprotein PK PF00224.21 CBY06960.1 - 8.5e-154 511.6 7.8 1.1e-153 511.2 7.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CBY06960.1 - 6.5e-35 119.9 0.1 2.5e-34 118.0 0.1 2.1 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 CBY06960.1 - 0.0025 16.9 2.9 0.0066 15.5 0.0 2.5 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain CPSase_L_D2 PF02786.17 CBY06961.1 - 3.7e-75 252.0 0.8 5.4e-75 251.5 0.1 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CBY06961.1 - 5.1e-66 222.2 0.0 2.6e-65 219.9 0.0 2.2 3 0 0 3 3 3 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CBY06961.1 - 1.4e-42 144.7 0.1 3.2e-42 143.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBY06961.1 - 1.6e-33 115.0 0.0 5.3e-33 113.3 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CBY06961.1 - 2.6e-25 89.5 0.0 6.4e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CBY06961.1 - 4.7e-16 58.4 0.1 3.8e-15 55.5 0.5 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CBY06961.1 - 4.6e-09 36.1 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBY06961.1 - 1.3e-06 28.1 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 CBY06961.1 - 0.00038 19.8 0.0 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 CBY06961.1 - 0.0015 18.6 0.1 0.004 17.2 0.0 1.8 2 0 0 2 2 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CBY06961.1 - 0.0016 18.2 0.1 0.0056 16.5 0.0 1.9 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.11 CBY06961.1 - 0.0091 15.6 0.0 0.05 13.2 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.19 CBY06961.1 - 0.02 14.7 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein ATPgrasp_YheCD PF14398.6 CBY06961.1 - 0.1 11.9 0.0 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp RnfC_N PF13375.6 CBY06961.1 - 0.12 12.3 0.7 0.26 11.2 0.2 1.8 2 0 0 2 2 1 0 RnfC Barrel sandwich hybrid domain GSH-S_ATP PF02955.16 CBY06961.1 - 0.14 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Peptidase_M23 PF01551.22 CBY06961.1 - 0.51 10.6 2.5 1.7 8.9 0.2 2.7 2 1 0 2 2 2 0 Peptidase family M23 MSP1_C PF07462.11 CBY06962.1 - 0.018 13.8 0.9 0.29 9.8 0.0 2.0 1 1 1 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus TSNAXIP1_N PF15739.5 CBY06962.1 - 0.087 13.2 0.2 0.36 11.2 0.1 2.0 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Trypsin PF00089.26 CBY06966.1 - 6.5e-40 137.3 0.0 1.7e-39 135.9 0.0 1.8 1 0 0 1 1 1 1 Trypsin TRIC PF05197.13 CBY06968.1 - 9.7e-12 44.9 3.1 1.3e-11 44.5 3.1 1.1 1 0 0 1 1 1 1 TRIC channel 7tm_1 PF00001.21 CBY06969.1 - 1.7e-05 24.3 1.0 2.5e-05 23.7 1.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cadherin_C_2 PF16492.5 CBY06969.1 - 0.092 13.5 0.2 33 5.3 0.0 3.0 2 1 1 3 3 3 0 Cadherin cytoplasmic C-terminal 7tm_1 PF00001.21 CBY06970.1 - 0.012 15.0 1.9 0.016 14.6 0.4 1.8 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) PMP22_Claudin PF00822.20 CBY06970.1 - 0.022 14.7 1.8 0.035 14.0 1.5 1.6 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family UPF0242 PF06785.11 CBY06970.1 - 0.083 13.0 1.5 0.16 12.1 1.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LRR_8 PF13855.6 CBY06972.1 - 3.1e-46 155.0 87.0 2.6e-13 49.5 10.1 5.2 2 1 5 7 7 7 6 Leucine rich repeat LRR_5 PF13306.6 CBY06972.1 - 1.7e-18 66.8 21.6 3.9e-10 39.8 1.0 2.9 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY06972.1 - 2.1e-16 59.7 53.2 1.2e-05 25.5 3.3 6.6 3 1 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY06972.1 - 4e-07 29.7 20.2 0.0019 17.7 5.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CBY06972.1 - 0.0019 18.5 44.7 1.1 10.1 0.1 10.1 9 1 0 9 9 9 3 Leucine Rich Repeat Lipocalin_3 PF12702.7 CBY06972.1 - 0.11 12.5 0.5 0.3 11.2 0.5 1.7 1 0 0 1 1 1 0 Lipocalin-like LRR_8 PF13855.6 CBY06973.1 - 4.6e-29 100.0 32.7 2.6e-13 49.5 7.0 4.3 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY06973.1 - 6.2e-14 51.9 25.1 0.0016 18.8 5.1 5.2 5 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY06973.1 - 5.4e-10 39.3 1.2 6.4e-06 26.2 0.1 2.8 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBY06973.1 - 0.0016 18.7 28.5 2.8 8.9 0.1 7.1 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 CBY06973.1 - 0.0016 18.0 10.3 0.0018 17.8 1.4 3.0 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CBY06973.1 - 0.0038 17.2 17.8 23 5.4 0.1 7.3 8 0 0 8 8 8 1 Leucine Rich repeat DUF3760 PF12586.8 CBY06973.1 - 0.01 16.0 0.4 8.2 6.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) EF-hand_6 PF13405.6 CBY06974.1 - 1.1e-12 46.8 1.3 7.1e-05 22.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY06974.1 - 1.7e-12 46.0 1.3 2.1e-05 23.7 0.0 3.7 3 1 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CBY06974.1 - 1.3e-08 35.2 0.2 0.0027 18.1 0.0 2.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY06974.1 - 1.5e-06 27.4 0.5 0.013 15.0 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY06974.1 - 0.00098 18.9 2.7 2.5 8.0 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_11 PF08976.11 CBY06974.1 - 0.18 12.7 0.0 0.31 11.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Phospholip_A2_1 PF00068.19 CBY06975.1 - 9.7e-14 51.8 8.1 1.9e-13 50.8 8.1 1.5 1 0 0 1 1 1 1 Phospholipase A2 Aldo_ket_red PF00248.21 CBY06976.1 - 2.7e-41 141.7 0.6 5.6e-41 140.7 0.6 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family HMGL-like PF00682.19 CBY06976.1 - 0.059 12.9 0.0 37 3.8 0.0 3.1 2 1 1 3 3 3 0 HMGL-like NmrA PF05368.13 CBY06976.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Ion_trans_2 PF07885.16 CBY06977.1 - 1e-21 76.7 17.1 1.8e-13 50.2 9.9 2.2 1 1 1 2 2 2 2 Ion channel Ion_trans PF00520.31 CBY06977.1 - 0.0012 18.1 6.4 0.13 11.5 0.8 2.3 1 1 1 2 2 2 2 Ion transport protein DUF812 PF05667.11 CBY06977.1 - 0.0033 16.4 15.4 0.0047 15.9 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF777 PF05606.11 CBY06977.1 - 0.019 14.7 0.9 0.045 13.5 0.9 1.6 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) FKBP_N_2 PF18023.1 CBY06977.1 - 2 8.6 9.4 0.098 12.8 3.1 1.9 2 0 0 2 2 2 0 BDBT FKBP like N-terminal Ion_trans PF00520.31 CBY06978.1 - 0.00062 19.1 8.8 0.0039 16.4 0.4 2.1 2 0 0 2 2 2 2 Ion transport protein WH2 PF02205.20 CBY06978.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 WH2 motif NACHT_N PF17100.5 CBY06978.1 - 0.55 10.0 4.5 1.5 8.6 4.5 1.7 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase KIP1 PF07765.12 CBY06978.1 - 2 8.6 9.9 0.88 9.7 5.0 2.9 2 1 1 3 3 3 0 KIP1-like protein dCMP_cyt_deam_1 PF00383.23 CBY06979.1 - 3.1e-16 59.1 0.1 4e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBY06979.1 - 1e-08 35.4 0.1 1.3e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region ZapD PF07072.11 CBY06980.1 - 0.011 15.5 6.3 0.066 13.0 0.0 2.4 2 0 0 2 2 2 0 Cell division protein Baculo_E25 PF05274.11 CBY06980.1 - 0.033 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 DUF501 PF04417.12 CBY06980.1 - 0.24 11.2 0.8 0.61 9.9 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF501) SurA_N_3 PF13624.6 CBY06980.1 - 1.3 8.8 5.8 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 SurA N-terminal domain CDI PF02234.19 CBY06981.1 - 0.014 15.5 0.3 0.025 14.7 0.3 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor DrsE_2 PF13686.6 CBY06982.1 - 0.019 14.8 1.0 0.035 14.0 1.0 1.4 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family SSF PF00474.17 CBY06983.1 - 4.5e-35 121.3 23.5 5.6e-35 121.0 23.5 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Zona_pellucida PF00100.23 CBY06984.1 - 5.7e-24 85.3 4.2 6.8e-24 85.1 4.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF1493 PF07377.12 CBY06984.1 - 0.0024 18.3 0.2 0.013 16.0 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1493) Trypsin PF00089.26 CBY06985.1 - 2.8e-45 154.8 0.0 4.2e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY06985.1 - 0.00012 23.0 0.0 0.00021 22.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY06985.1 - 0.038 14.4 0.3 0.069 13.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) DUF1180 PF06679.12 CBY06986.1 - 0.089 13.2 0.9 0.1 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3583 PF12126.8 CBY06986.1 - 0.81 9.1 3.9 1.3 8.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) MSA-2c PF12238.8 CBY06986.1 - 2.5 8.0 7.7 3.4 7.6 7.7 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Alkyl_sulf_dimr PF14863.6 CBY06987.1 - 1.2e-38 132.8 0.0 1.8e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 CBY06987.1 - 7e-08 32.7 0.1 4.7e-07 30.0 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY06987.1 - 0.0018 17.8 0.0 0.014 14.9 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Alkyl_sulf_C PF14864.6 CBY06987.1 - 0.0039 17.5 0.0 0.0079 16.5 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Spy1 PF11357.8 CBY06988.1 - 7e-43 146.1 3.2 8.8e-43 145.7 3.2 1.1 1 0 0 1 1 1 1 Cell cycle regulatory protein ABC_tran PF00005.27 CBY06989.1 - 1.9e-54 183.9 0.0 1.7e-27 96.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CBY06989.1 - 1.1e-38 133.2 45.7 8.5e-24 84.3 14.8 3.0 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBY06989.1 - 7.2e-24 85.1 8.5 1.6e-07 31.4 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY06989.1 - 2.6e-08 33.6 2.3 0.15 11.5 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBY06989.1 - 2.5e-07 30.3 0.2 0.0041 16.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBY06989.1 - 2.5e-07 30.7 0.4 0.00019 21.4 0.1 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CBY06989.1 - 1.1e-05 26.0 11.5 0.00044 20.8 0.0 3.7 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 CBY06989.1 - 1.1e-05 25.8 0.1 0.028 14.8 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain MukB PF04310.12 CBY06989.1 - 3.6e-05 23.7 0.3 0.027 14.3 0.0 2.4 2 0 0 2 2 2 2 MukB N-terminal MMR_HSR1 PF01926.23 CBY06989.1 - 9.4e-05 22.5 0.1 0.77 9.9 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_27 PF13514.6 CBY06989.1 - 0.00017 21.3 0.1 0.19 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CBY06989.1 - 0.00068 19.4 14.0 0.64 9.7 0.0 4.9 4 2 2 6 6 6 3 AAA ATPase domain AAA_30 PF13604.6 CBY06989.1 - 0.00076 19.3 0.0 0.57 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 CBY06989.1 - 0.00097 19.8 1.6 0.0045 17.7 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA PF00004.29 CBY06989.1 - 0.002 18.6 0.1 2.3 8.7 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CBY06989.1 - 0.0026 17.1 0.0 0.74 9.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 CBY06989.1 - 0.0046 17.2 0.2 3.7 7.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBY06989.1 - 0.0054 17.1 0.3 1.6 9.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 CBY06989.1 - 0.015 15.0 0.1 3.8 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 CBY06989.1 - 0.025 14.5 0.1 3.6 7.5 0.0 2.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 CBY06989.1 - 0.049 13.7 0.0 17 5.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain VirE PF05272.11 CBY06989.1 - 0.056 13.2 0.1 0.72 9.6 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_33 PF13671.6 CBY06989.1 - 0.14 12.3 0.2 6.7 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CBY06989.1 - 0.24 11.6 1.2 30 4.8 0.1 2.7 3 0 0 3 3 3 0 AAA domain ABC2_membrane_2 PF12679.7 CBY06989.1 - 6.9 5.9 15.6 19 4.4 15.6 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein Trypsin PF00089.26 CBY06990.1 - 8.6e-47 159.8 0.3 8.6e-47 159.8 0.3 1.8 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY06990.1 - 4.5e-07 30.9 0.2 3.1e-06 28.2 0.1 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain Mucin PF01456.17 CBY06990.1 - 5.7e-06 26.4 27.8 1.4e-05 25.1 27.8 1.7 1 0 0 1 1 1 1 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 CBY06990.1 - 1.5 9.0 20.2 3.1 8.0 20.2 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus MGC-24 PF05283.11 CBY06990.1 - 1.6 9.1 19.2 4.2 7.8 19.2 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Med13_C PF06333.12 CBY06990.1 - 2 7.6 12.5 3 7.0 12.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Dicty_REP PF05086.12 CBY06990.1 - 2.2 6.2 11.4 3.3 5.6 11.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ATP19 PF11022.8 CBY06991.1 - 0.43 11.0 5.9 7.9 6.9 0.0 3.3 3 0 0 3 3 3 0 ATP synthase subunit K Trypsin PF00089.26 CBY06992.1 - 2.6e-52 177.8 3.0 8.2e-52 176.2 3.0 1.7 1 1 0 1 1 1 1 Trypsin DUF3011 PF11218.8 CBY06995.1 - 3.5e-14 53.3 0.2 6.6e-14 52.4 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3011) zf-CCCH PF00642.24 CBY06997.1 - 4.7e-08 32.8 18.8 2.2e-05 24.2 0.4 4.5 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CBY06997.1 - 1.5e-07 31.6 5.9 0.00064 19.9 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CBY06997.1 - 0.022 15.2 25.9 0.17 12.4 1.2 4.5 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger Abhydrolase_3 PF07859.13 CBY06998.1 - 5.5e-12 46.0 0.1 1.3e-11 44.8 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY06998.1 - 5.2e-09 35.9 0.0 8.8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 CBY06998.1 - 7.9e-06 25.6 0.1 2.3e-05 24.1 0.1 1.6 1 1 1 2 2 2 1 Lipid-droplet associated hydrolase COesterase PF00135.28 CBY06998.1 - 2.7e-05 23.2 1.4 0.00042 19.3 0.0 2.2 2 1 0 2 2 2 1 Carboxylesterase family FSH1 PF03959.13 CBY06998.1 - 0.0039 16.9 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF3530 PF12048.8 CBY06998.1 - 0.007 15.8 0.0 0.0089 15.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3530) Hydrolase_4 PF12146.8 CBY06998.1 - 0.013 14.7 0.2 0.035 13.4 0.2 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 CBY06998.1 - 0.087 12.4 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CBY06998.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 CBY06998.1 - 0.11 13.1 0.3 0.26 11.9 0.4 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Kelch_1 PF01344.25 CBY06999.1 - 0.00047 19.7 0.0 0.076 12.6 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBY06999.1 - 0.0005 20.3 0.1 0.34 11.3 0.0 2.3 2 0 0 2 2 2 2 Kelch motif TSP_1 PF00090.19 CBY07000.1 - 6.7e-12 45.4 18.4 1.6e-08 34.6 7.7 18.4 18 1 0 18 18 18 9 Thrombospondin type 1 domain zf-HIT PF04438.16 CBY07001.1 - 0.00017 21.4 11.3 0.00028 20.7 11.3 1.3 1 0 0 1 1 1 1 HIT zinc finger TFCD_C PF12612.8 CBY07002.1 - 2e-24 86.5 0.3 2e-24 86.5 0.3 4.7 5 1 1 6 6 6 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.6 CBY07002.1 - 6.2e-07 29.8 4.0 0.0013 19.2 0.0 6.1 6 2 1 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 CBY07002.1 - 2.1e-06 28.0 3.1 0.03 14.7 0.1 5.0 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 CBY07002.1 - 6.1e-05 22.9 15.6 0.0033 17.6 0.1 7.4 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.7 CBY07002.1 - 0.0026 17.8 6.5 0.007 16.4 0.0 4.5 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CBY07002.1 - 0.026 14.7 4.7 27 5.0 0.1 4.5 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 CBY07002.1 - 0.05 13.2 3.5 9.6 5.7 0.0 4.3 3 2 3 6 6 6 0 CLASP N terminal Cohesin_HEAT PF12765.7 CBY07002.1 - 0.067 13.5 0.1 0.3 11.4 0.1 2.1 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 CBY07002.1 - 0.1 13.2 0.9 2.8 8.6 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region CDP-OH_P_transf PF01066.21 CBY07003.1 - 5.6e-13 49.5 0.1 5.6e-13 49.5 0.1 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PsbJ PF01788.17 CBY07003.1 - 0.0058 16.5 1.8 0.0058 16.5 1.8 1.7 2 0 0 2 2 2 1 PsbJ Apolipoprotein PF01442.18 CBY07003.1 - 0.008 16.1 16.1 0.013 15.4 16.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Transformer PF06495.11 CBY07003.1 - 0.32 11.1 11.8 0.49 10.5 11.8 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein SAPS PF04499.15 CBY07003.1 - 0.58 8.9 6.5 0.76 8.5 6.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ribosomal_L7Ae PF01248.26 CBY07004.1 - 1.8e-22 78.9 0.0 2e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 CBY07004.1 - 0.037 14.1 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_S25 PF03297.15 CBY07005.1 - 9e-43 144.6 1.5 1e-42 144.4 1.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein AIPR PF10592.9 CBY07005.1 - 0.019 14.6 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 AIPR protein Hema_HEFG PF02710.14 CBY07006.1 - 0.0054 16.9 2.0 0.0069 16.6 0.6 1.8 1 1 1 2 2 2 1 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein IL23 PF16649.5 CBY07006.1 - 0.073 13.1 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Interleukin 23 subunit alpha zn-ribbon_14 PF16503.5 CBY07006.1 - 5.1 6.7 8.8 0.21 11.1 0.8 2.3 2 0 0 2 2 2 0 Zinc-ribbon Trypsin PF00089.26 CBY07007.1 - 1.6e-56 191.6 0.0 2.3e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 CBY07007.1 - 8.6e-56 186.2 36.7 2.8e-21 75.6 7.8 3.5 3 0 0 3 3 3 3 Kringle domain DUF1986 PF09342.11 CBY07007.1 - 6.4e-07 29.8 0.0 1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY07007.1 - 0.00077 20.4 0.1 0.0019 19.1 0.1 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Toxin_5 PF05294.13 CBY07007.1 - 2 8.9 12.9 14 6.2 2.3 4.0 3 0 0 3 3 3 0 Scorpion short toxin CUB PF00431.20 CBY07008.1 - 1.4e-05 25.4 0.1 0.0004 20.7 0.0 2.2 2 0 0 2 2 2 2 CUB domain Tetraspanin PF00335.20 CBY07009.1 - 7.5e-16 58.5 1.5 1e-15 58.1 1.5 1.2 1 0 0 1 1 1 1 Tetraspanin family VEGFR-2_TMD PF17988.1 CBY07009.1 - 0.014 14.8 1.6 0.24 10.9 0.2 2.7 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain Claudin_2 PF13903.6 CBY07009.1 - 0.12 12.1 13.0 0.045 13.5 4.5 3.0 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Peptidase_M13_N PF05649.13 CBY07010.1 - 2.3e-93 313.9 0.6 3.2e-93 313.5 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CBY07010.1 - 4.6e-71 238.7 1.0 4.6e-71 238.7 1.0 1.9 2 0 0 2 2 2 1 Peptidase family M13 Imm52 PF15579.6 CBY07010.1 - 0.077 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 52 DUF1104 PF06518.11 CBY07010.1 - 0.38 11.2 2.3 27 5.2 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) zf-RING_2 PF13639.6 CBY07011.1 - 2.1e-13 50.4 5.3 2.1e-13 50.4 5.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY07011.1 - 7.6e-11 41.7 5.0 7.6e-11 41.7 5.0 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY07011.1 - 4.1e-10 39.2 2.9 1.5e-09 37.4 2.9 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CBY07011.1 - 9.8e-10 38.6 8.6 9.8e-10 38.6 8.6 3.2 2 2 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBY07011.1 - 1.7e-08 34.2 5.9 1.7e-08 34.2 5.9 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY07011.1 - 8.1e-08 32.1 15.0 1.3e-07 31.4 5.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY07011.1 - 4.1e-07 29.9 3.1 4.1e-07 29.9 3.1 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY07011.1 - 2.6e-06 27.2 10.6 1.9e-05 24.4 3.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBY07011.1 - 9.7e-06 25.1 3.4 9.7e-06 25.1 3.4 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CBY07011.1 - 2.7e-05 24.1 5.2 2.7e-05 24.1 5.2 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBY07011.1 - 4.1e-05 23.3 4.0 4.1e-05 23.3 4.0 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 FYDLN_acid PF09538.10 CBY07011.1 - 0.0019 18.8 0.7 0.0019 18.8 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (FYDLN_acid) zinc_ribbon_9 PF14369.6 CBY07011.1 - 0.0022 18.2 10.4 0.0052 17.0 3.2 3.4 3 0 0 3 3 3 1 zinc-ribbon zf-Nse PF11789.8 CBY07011.1 - 0.0094 15.7 1.9 0.0094 15.7 1.9 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CBY07011.1 - 0.01 16.0 6.5 0.01 16.0 6.5 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain DZR PF12773.7 CBY07011.1 - 0.029 14.4 0.8 0.029 14.4 0.8 3.0 2 1 0 2 2 2 0 Double zinc ribbon U1snRNP70_N PF12220.8 CBY07011.1 - 0.1 13.3 3.7 0.37 11.5 0.1 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-HC5HC2H_2 PF13832.6 CBY07011.1 - 0.51 10.5 9.9 0.17 12.0 4.3 2.5 2 1 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBY07011.1 - 0.56 10.5 12.2 0.75 10.1 5.8 2.8 2 1 0 2 2 2 0 PHD-like zinc-binding domain PHD PF00628.29 CBY07011.1 - 1.3 8.9 14.4 1.2 9.0 4.9 2.8 2 0 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 CBY07011.1 - 3.8 7.6 14.4 1.6 8.8 1.3 2.8 2 1 1 3 3 3 0 zinc-ribbons Zf_RING PF16744.5 CBY07011.1 - 4.3 7.5 8.8 0.49 10.6 2.2 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger Rho_GDI PF02115.17 CBY07012.1 - 2.8e-70 236.0 3.8 3.4e-70 235.8 3.8 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.15 CBY07012.1 - 0.012 16.1 0.1 0.093 13.2 0.1 2.0 1 1 0 1 1 1 0 ML domain tRNA-synt_His PF13393.6 CBY07012.1 - 0.019 14.3 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase NTS PF15447.6 CBY07012.1 - 0.24 11.9 0.7 0.24 11.9 0.7 2.5 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 Nop25 PF09805.9 CBY07013.1 - 5.9e-13 49.5 27.3 1.9e-12 47.8 27.3 1.8 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) DFF-C PF09033.10 CBY07013.1 - 0.0094 15.9 9.7 0.013 15.4 9.7 1.3 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain AvrB_AvrC PF05394.11 CBY07013.1 - 0.059 12.6 4.6 0.076 12.2 4.6 1.1 1 0 0 1 1 1 0 Avirulence protein DUF4407 PF14362.6 CBY07013.1 - 1.5 8.1 15.2 1.8 7.8 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EF-hand_6 PF13405.6 CBY07014.1 - 0.11 12.5 0.0 0.37 10.8 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Ank_2 PF12796.7 CBY07015.1 - 3.6e-29 101.2 0.3 1.8e-12 47.7 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY07015.1 - 1.8e-26 92.2 1.2 3.6e-07 30.6 0.0 4.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY07015.1 - 2.2e-26 91.6 0.8 1.4e-08 34.8 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY07015.1 - 9.7e-25 85.9 1.2 3.2e-05 24.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CBY07015.1 - 1.1e-21 74.6 0.5 0.0005 20.3 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat CYLD_phos_site PF16607.5 CBY07015.1 - 0.032 14.1 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Phosphorylation region of CYLD, unstructured DnaJ PF00226.31 CBY07016.1 - 4.8e-23 81.1 0.4 9e-23 80.2 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain JLPA PF16668.5 CBY07016.1 - 0.014 14.4 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 Adhesin from Campylobacter Ploopntkinase2 PF18747.1 CBY07016.1 - 0.035 13.4 0.1 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 LRR_8 PF13855.6 CBY07018.1 - 1.2e-08 34.6 5.8 0.00053 19.7 1.3 3.6 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CBY07018.1 - 2.2e-08 34.3 8.4 0.003 17.9 0.8 4.3 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) CUE PF02845.16 CBY07018.1 - 6.7e-07 28.9 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain LRR_9 PF14580.6 CBY07018.1 - 0.0035 16.9 1.6 0.11 11.9 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CBY07018.1 - 0.21 11.8 3.2 20 5.6 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich repeat PEMT PF04191.13 CBY07019.1 - 0.0046 17.3 4.7 0.0095 16.3 4.0 1.9 1 1 0 1 1 1 1 Phospholipid methyltransferase DnaJ PF00226.31 CBY07020.1 - 4.7e-08 33.0 0.2 5.1e-07 29.7 0.2 2.5 1 1 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 CBY07020.1 - 8e-08 31.8 2.3 0.001 18.3 0.0 3.0 2 1 0 2 2 2 2 Sec63 Brl domain SNF PF00209.18 CBY07021.1 - 3.9e-163 543.9 39.6 6.7e-163 543.1 39.6 1.3 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Myosin_head PF00063.21 CBY07022.1 - 9.9e-252 837.0 0.0 9.9e-252 837.0 0.0 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY07022.1 - 2.4e-138 462.8 260.1 3.3e-138 462.3 260.1 1.1 1 0 0 1 1 1 1 Myosin tail MFS_1 PF07690.16 CBY07022.1 - 4.6e-19 68.6 29.3 6.3e-19 68.1 29.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBY07022.1 - 0.00018 20.0 0.4 0.00018 20.0 0.4 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family AAA_22 PF13401.6 CBY07022.1 - 0.1 12.9 0.0 0.1 12.9 0.0 5.8 4 3 4 8 8 8 0 AAA domain Phage_int_SAM_1 PF02899.17 CBY07022.1 - 0.48 10.8 10.6 0.61 10.4 2.6 4.6 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain NuiA PF07924.11 CBY07023.1 - 0.011 16.1 0.1 0.028 14.8 0.1 1.7 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Kelch_5 PF13854.6 CBY07024.1 - 0.025 14.6 0.1 3.5 7.7 0.0 3.0 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CBY07024.1 - 0.051 13.2 1.6 2.5 7.7 0.0 3.6 5 0 0 5 5 5 0 Kelch motif RecG_wedge PF17191.4 CBY07024.1 - 0.055 13.1 0.0 2.1 8.0 0.0 2.6 2 1 1 3 3 3 0 RecG wedge domain FXa_inhibition PF14670.6 CBY07025.1 - 0.0002 21.5 8.2 0.00077 19.7 8.2 2.1 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site NIR_SIR PF01077.22 CBY07025.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Tubulin-binding PF00418.19 CBY07028.1 - 1.3e-07 31.5 0.0 2.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Tau and MAP protein, tubulin-binding repeat Tubulin-binding PF00418.19 CBY07029.1 - 1.8e-09 37.4 0.1 7.2e-09 35.5 0.1 1.8 2 0 0 2 2 2 1 Tau and MAP protein, tubulin-binding repeat GpcrRhopsn4 PF10192.9 CBY07030.1 - 0.00095 18.6 0.1 0.0013 18.2 0.1 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF1600 PF07667.11 CBY07030.1 - 0.023 14.9 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) CcmD PF04995.14 CBY07031.1 - 0.011 15.8 0.2 0.017 15.2 0.2 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NicO PF03824.16 CBY07031.1 - 0.027 13.8 0.1 0.028 13.8 0.1 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein Comm PF15957.5 CBY07031.1 - 0.027 14.8 0.5 0.03 14.7 0.5 1.0 1 0 0 1 1 1 0 Commissureless EOS1 PF12326.8 CBY07031.1 - 0.04 13.9 0.2 0.04 13.8 0.2 1.1 1 0 0 1 1 1 0 N-glycosylation protein OSTbeta PF15048.6 CBY07031.1 - 0.042 14.0 0.1 0.048 13.8 0.1 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Cation_efflux PF01545.21 CBY07033.1 - 3e-41 141.3 12.1 4.1e-41 140.9 12.1 1.2 1 0 0 1 1 1 1 Cation efflux family Lectin_C PF00059.21 CBY07033.1 - 6.4e-38 129.8 27.0 6.7e-14 52.5 2.9 5.7 5 1 0 5 5 5 5 Lectin C-type domain DUF1282 PF06930.12 CBY07033.1 - 0.39 10.5 2.4 0.27 11.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Ribonuclease_T2 PF00445.18 CBY07034.1 - 5.4e-19 69.1 0.6 8.4e-19 68.5 0.6 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family DUF4064 PF13273.6 CBY07034.1 - 0.061 13.6 0.9 0.1 12.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) C1q PF00386.21 CBY07035.1 - 2.6e-14 53.5 0.6 4.5e-14 52.8 0.6 1.4 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 CBY07035.1 - 0.00023 20.8 5.1 0.00037 20.2 5.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) CTP_transf_like PF01467.26 CBY07036.1 - 4.8e-21 75.4 0.1 1.6e-20 73.7 0.1 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like DHHC PF01529.20 CBY07037.1 - 3.6e-22 78.9 18.4 3.6e-22 78.9 18.4 1.3 1 1 0 1 1 1 1 DHHC palmitoyltransferase RPE65 PF03055.15 CBY07038.1 - 3.2e-14 53.0 0.1 3.8e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3808 PF10300.9 CBY07039.1 - 6e-74 249.5 4.0 1e-73 248.7 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 CBY07039.1 - 0.0002 21.8 0.4 0.043 14.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY07039.1 - 0.0017 18.6 2.2 0.93 9.8 0.2 3.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CBY07039.1 - 0.016 15.3 4.0 40 4.7 0.1 5.8 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY07039.1 - 0.14 12.9 0.0 8.8 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY07039.1 - 0.62 10.4 6.5 1.9 8.9 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Astacin PF01400.24 CBY07040.1 - 1.3e-36 126.0 0.1 2.5e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY07040.1 - 0.00031 20.9 6.6 0.00031 20.9 6.6 2.5 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Phospholip_A2_1 PF00068.19 CBY07041.1 - 4.5e-13 49.6 2.7 4.5e-13 49.6 2.7 2.3 1 1 1 2 2 2 1 Phospholipase A2 Sulfotransfer_2 PF03567.14 CBY07042.1 - 3.6e-16 59.8 3.1 5.4e-16 59.3 3.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 CBY07042.1 - 1.3e-05 24.3 0.9 3e-05 23.1 0.9 1.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 CBY07042.1 - 0.00053 19.5 0.5 0.0012 18.4 0.3 1.7 1 1 0 1 1 1 1 Sulfotransferase domain GCV_T PF01571.21 CBY07043.1 - 9.4e-75 251.3 0.0 1.2e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CBY07043.1 - 1.4e-23 82.6 0.0 2.5e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CBY07043.1 - 3.3e-07 30.5 0.5 3.8e-05 23.9 0.0 2.2 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family Astacin PF01400.24 CBY07044.1 - 2.1e-36 125.4 0.0 2.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CBY07044.1 - 6.3e-05 22.9 0.1 8.9e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Matrixin Astacin PF01400.24 CBY07045.1 - 6e-07 29.3 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) PLAC8 PF04749.17 CBY07046.1 - 2.7e-11 44.3 3.7 3.1e-11 44.1 3.7 1.1 1 0 0 1 1 1 1 PLAC8 family Peptidase_M2 PF01401.18 CBY07047.1 - 7.3e-171 569.6 19.1 1.6e-165 552.0 6.5 2.0 1 1 0 2 2 2 2 Angiotensin-converting enzyme LZ3wCH PF18517.1 CBY07047.1 - 0.033 14.3 0.6 0.093 12.9 0.6 1.8 1 0 0 1 1 1 0 Leucine zipper with capping helix domain ABC_tran_CTD PF16326.5 CBY07047.1 - 0.6 10.4 6.2 2.5 8.4 6.2 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain Homeodomain PF00046.29 CBY07049.1 - 4.2e-22 77.7 6.9 4.2e-22 77.7 6.9 2.2 2 1 0 2 2 2 1 Homeodomain QLQ PF08880.11 CBY07049.1 - 0.00076 19.2 3.7 0.0022 17.7 0.6 2.5 2 0 0 2 2 2 1 QLQ GAIN_A PF18619.1 CBY07049.1 - 0.26 11.5 2.2 0.39 11.0 0.4 2.1 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A HNF-1_N PF04814.13 CBY07051.1 - 5.8e-33 115.2 0.5 1.2e-32 114.2 0.1 1.7 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 CBY07051.1 - 2.6e-05 24.0 4.9 8.1e-05 22.4 2.3 2.9 2 1 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY07051.1 - 0.1 12.5 0.1 0.93 9.5 0.1 2.6 2 1 0 2 2 2 0 Homeobox KN domain HTH_5 PF01022.20 CBY07051.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Kinesin PF00225.23 CBY07052.1 - 5.7e-89 298.3 2.0 9.1e-89 297.7 2.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY07052.1 - 1.5e-28 99.6 0.0 4.4e-28 98.1 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 CBY07052.1 - 0.012 15.8 4.0 0.035 14.2 1.0 2.5 2 0 0 2 2 2 0 Kinesin-associated TolA_bind_tri PF16331.5 CBY07052.1 - 0.21 11.7 0.0 0.21 11.7 0.0 3.0 2 1 0 2 2 2 0 TolA binding protein trimerisation HALZ PF02183.18 CBY07052.1 - 0.22 11.7 0.2 0.22 11.7 0.2 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper OmpH PF03938.14 CBY07052.1 - 2.7 8.3 12.5 6.1 7.2 12.5 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_16 PF13191.6 CBY07052.1 - 3.3 8.1 5.1 17 5.7 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain PHD_like PF12910.7 CBY07053.1 - 0.067 13.2 0.0 0.16 12.0 0.0 1.7 2 1 0 2 2 2 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system MttA_Hcf106 PF02416.16 CBY07053.1 - 0.079 12.3 0.4 0.15 11.4 0.2 1.5 2 0 0 2 2 2 0 mttA/Hcf106 family DUF3254 PF11630.8 CBY07053.1 - 0.09 13.0 0.1 0.22 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3254) FTR1 PF03239.14 CBY07053.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family Astacin PF01400.24 CBY07055.1 - 5.6e-11 42.4 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY07055.1 - 3.8e-06 27.0 8.0 3.8e-06 27.0 8.0 4.1 4 0 0 4 4 4 2 Calcium-binding EGF domain UPF0054 PF02130.17 CBY07055.1 - 0.25 11.2 0.6 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 YMF19 PF02326.15 CBY07056.1 - 0.0014 19.4 0.4 0.0025 18.5 0.4 1.4 1 0 0 1 1 1 1 Plant ATP synthase F0 LRR_8 PF13855.6 CBY07057.1 - 5.7e-23 80.4 18.0 4.8e-09 35.8 1.0 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 CBY07057.1 - 4.9e-11 42.7 1.2 8.3e-11 41.9 1.2 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY07057.1 - 4.8e-06 26.8 9.1 0.0015 18.9 3.8 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY07057.1 - 0.00032 20.3 1.7 0.03 13.8 1.3 2.3 2 1 1 3 3 3 2 Leucine-rich repeat LRR_3 PF07725.12 CBY07057.1 - 0.0013 18.5 1.2 8.5 6.4 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_1 PF00560.33 CBY07057.1 - 3.7 8.4 9.7 95 4.2 0.3 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 CBY07058.1 - 1.8e-22 80.0 10.8 8.7e-13 48.2 0.2 3.0 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY07058.1 - 1.3e-16 60.7 0.1 8.5e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBY07058.1 - 0.06 13.3 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2149 PF09919.9 CBY07062.1 - 0.11 12.8 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) OLF PF02191.16 CBY07063.1 - 5.2e-10 39.3 0.2 7e-10 38.9 0.2 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Pkinase_Tyr PF07714.17 CBY07064.1 - 2.4e-54 184.3 0.2 3.1e-54 184.0 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY07064.1 - 6e-37 127.4 0.2 7.5e-37 127.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CBY07064.1 - 4.3e-05 22.6 0.6 5.9e-05 22.2 0.6 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY07064.1 - 0.00023 20.6 0.1 0.00056 19.3 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY07064.1 - 0.00075 18.4 0.1 0.0011 17.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 CBY07064.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Kdo PF06293.14 CBY07064.1 - 0.0034 16.8 0.6 0.0052 16.2 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY07064.1 - 0.029 14.3 0.3 0.051 13.5 0.3 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CBY07064.1 - 0.035 13.7 1.6 0.051 13.2 0.1 1.9 2 1 0 2 2 2 0 RIO1 family LIM PF00412.22 CBY07065.1 - 1e-23 83.3 43.7 4.3e-09 36.5 12.0 3.5 3 0 0 3 3 3 3 LIM domain DpnI PF06044.12 CBY07065.1 - 5 6.7 14.3 0.22 11.2 7.4 2.1 1 1 1 2 2 2 0 Dam-replacing family Glyco_hydro_20 PF00728.22 CBY07066.1 - 2.4e-74 250.9 1.7 5e-73 246.5 1.7 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CBY07066.1 - 5.7e-15 56.2 0.0 8.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CBY07066.1 - 0.00043 21.0 0.0 0.0021 18.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 DUF5570 PF17731.1 CBY07067.1 - 0.0058 16.7 0.0 0.0065 16.6 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5570) Bac_GH3_C PF18034.1 CBY07067.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain Chitin_synth_2 PF03142.15 CBY07068.1 - 3.1e-26 92.1 5.7 2.9e-23 82.3 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CBY07068.1 - 2.7e-07 30.7 9.3 2.7e-07 30.7 9.3 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CBY07068.1 - 0.00021 21.2 0.0 0.00044 20.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CBY07068.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ig_3 PF13927.6 CBY07071.1 - 6.3e-25 87.6 1.7 6.6e-06 26.6 0.0 5.8 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 CBY07071.1 - 1.5e-18 66.6 4.2 2.8e-06 27.3 0.1 6.5 4 3 1 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY07071.1 - 2.9e-16 59.6 0.0 0.0019 18.5 0.0 4.9 4 1 1 5 5 5 4 Immunoglobulin domain ig PF00047.25 CBY07071.1 - 3.9e-08 33.4 4.9 1.6 9.0 0.3 6.7 5 2 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY07071.1 - 4.4e-08 33.1 1.9 0.0029 17.6 0.0 5.0 4 2 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CBY07071.1 - 8.6e-08 32.3 0.2 0.00013 22.1 0.1 4.9 5 1 0 5 5 5 1 Immunoglobulin V-set domain C1-set PF07654.15 CBY07071.1 - 0.084 13.3 0.4 1.1e+02 3.3 0.0 4.9 6 0 0 6 6 6 0 Immunoglobulin C1-set domain PKD_3 PF16820.5 CBY07071.1 - 0.094 12.5 0.0 0.42 10.4 0.0 2.2 1 0 0 1 1 1 0 PKD-like domain FAM24 PF15193.6 CBY07072.1 - 2.6 8.9 9.1 0.65 10.8 4.5 2.5 2 0 0 2 2 2 0 FAM24 family Hydantoinase_B PF02538.14 CBY07073.1 - 4.1e-205 682.1 0.1 5.4e-205 681.7 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CBY07073.1 - 5.2e-98 327.9 0.0 1e-97 327.0 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CBY07073.1 - 1.9e-53 180.8 0.1 2.8e-51 173.7 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region SOP4 PF17081.5 CBY07073.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein Sugar_tr PF00083.24 CBY07074.1 - 9.4e-15 54.4 3.5 9.4e-15 54.4 3.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY07074.1 - 5.6e-10 38.7 42.3 5.6e-10 38.7 42.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily T-box PF00907.22 CBY07075.1 - 4.1e-73 245.6 0.1 4.1e-73 245.6 0.1 1.8 3 0 0 3 3 3 1 T-box Tropomyosin PF00261.20 CBY07076.1 - 1.7e-48 165.1 45.6 3.8e-46 157.4 34.9 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 CBY07076.1 - 8.8e-12 45.4 42.8 3e-11 43.7 23.6 3.2 1 1 2 3 3 3 2 Tropomyosin like ATG16 PF08614.11 CBY07076.1 - 0.00088 19.6 27.4 0.027 14.7 13.8 2.5 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Tektin PF03148.14 CBY07076.1 - 0.0016 17.3 28.1 0.023 13.4 16.9 2.6 1 1 2 3 3 3 2 Tektin family Lebercilin PF15619.6 CBY07076.1 - 0.0024 17.6 31.9 0.0033 17.1 7.2 2.5 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Laminin_II PF06009.12 CBY07076.1 - 0.0059 16.6 24.5 0.052 13.6 2.7 3.7 1 1 2 3 3 3 3 Laminin Domain II DUF745 PF05335.13 CBY07076.1 - 0.0075 16.0 18.6 0.15 11.8 0.9 3.2 1 1 1 3 3 3 2 Protein of unknown function (DUF745) DUF1794 PF08768.11 CBY07076.1 - 0.15 12.0 1.8 5.6 6.9 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1794) KxDL PF10241.9 CBY07076.1 - 0.28 11.5 10.7 1.4 9.2 0.0 4.2 2 1 3 5 5 5 0 Uncharacterized conserved protein Cytochrom_C_2 PF01322.20 CBY07076.1 - 0.42 11.5 9.7 0.49 11.3 2.5 2.9 2 1 0 2 2 2 0 Cytochrome C' Spc7 PF08317.11 CBY07076.1 - 1.1 8.1 36.9 3.6 6.4 21.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CBY07076.1 - 1.3 9.1 22.1 0.75 9.8 3.9 3.7 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.11 CBY07076.1 - 1.5 7.6 34.1 1.9 7.3 34.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1464 PF07318.12 CBY07076.1 - 2.1 7.4 4.5 0.69 9.0 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) GPS2_interact PF15784.5 CBY07076.1 - 2.3 8.7 18.4 0.17 12.3 0.9 3.9 1 1 3 4 4 4 0 G-protein pathway suppressor 2-interacting domain TPR_MLP1_2 PF07926.12 CBY07076.1 - 2.9 8.0 34.3 0.061 13.4 3.8 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 CBY07076.1 - 3.9 6.7 32.5 0.029 13.7 4.9 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF3450) ERM PF00769.19 CBY07076.1 - 7.6 6.3 40.2 0.8 9.5 5.0 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Fez1 PF06818.15 CBY07076.1 - 8.6 6.8 32.4 2.2 8.7 12.1 2.6 1 1 1 2 2 2 0 Fez1 Jnk-SapK_ap_N PF09744.9 CBY07076.1 - 10 6.4 37.8 13 6.0 17.9 3.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Mod_r PF07200.13 CBY07077.1 - 0.06 13.5 0.6 0.45 10.6 0.1 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Methyltr_RsmB-F PF01189.17 CBY07078.1 - 2.9e-71 239.3 0.0 6.5e-71 238.1 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CBY07078.1 - 5.1e-09 36.5 0.0 1.4e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CBY07078.1 - 5.9e-05 23.2 0.0 0.00019 21.6 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 CBY07078.1 - 0.025 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CBY07078.1 - 0.035 13.9 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CBY07078.1 - 0.035 14.8 0.0 0.074 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Sulfotransfer_4 PF17784.1 CBY07079.1 - 3.5e-42 144.7 0.2 4.3e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY07079.1 - 0.0065 16.9 0.1 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family SHIPPO-rpt PF07004.12 CBY07080.1 - 0.015 16.2 40.5 0.25 12.3 0.1 9.0 8 4 0 8 8 8 0 Sperm-tail PG-rich repeat Sulfatase PF00884.23 CBY07081.1 - 4.4e-20 72.3 0.3 1.7e-10 40.8 0.1 2.0 2 0 0 2 2 2 2 Sulfatase Sulfotransfer_2 PF03567.14 CBY07082.1 - 1.5e-17 64.4 1.0 3.8e-17 63.0 1.0 1.7 1 0 0 1 1 1 1 Sulfotransferase family Hum_adeno_E3A PF05393.11 CBY07082.1 - 0.033 14.2 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF3914 PF13053.6 CBY07082.1 - 0.11 12.9 0.2 0.74 10.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3914) TRAP_alpha PF03896.16 CBY07083.1 - 1.2 8.2 6.7 1.4 8.1 6.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 CBY07083.1 - 4.3 5.4 21.8 4.6 5.3 21.8 1.0 1 0 0 1 1 1 0 Nop14-like family NAM-associated PF14303.6 CBY07084.1 - 0.0012 19.6 15.5 0.0014 19.3 15.5 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain PDDEXK_6 PF04720.12 CBY07084.1 - 0.53 10.2 8.8 0.61 10.0 8.8 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function TMPIT PF07851.13 CBY07084.1 - 2.6 7.2 12.5 3.4 6.8 12.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Neur_chan_memb PF02932.16 CBY07084.1 - 3.6 7.6 7.5 4.3 7.3 7.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EIIBC-GUT_N PF03612.14 CBY07084.1 - 5.8 6.6 9.3 8.6 6.1 9.0 1.5 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Tubulin PF00091.25 CBY07085.1 - 3.2e-69 233.1 0.0 5.3e-69 232.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY07085.1 - 1.6e-43 147.8 0.1 2.7e-43 147.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY07085.1 - 9.1e-06 26.0 0.0 2.5e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBY07085.1 - 0.007 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBY07085.1 - 0.015 14.5 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin like EF-hand_1 PF00036.32 CBY07087.1 - 0.016 14.7 0.9 0.075 12.6 0.1 2.5 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 CBY07087.1 - 0.11 12.0 5.5 0.15 11.6 0.1 2.9 3 0 0 3 3 3 0 EF hand Sulfotransfer_2 PF03567.14 CBY07088.1 - 2.5e-22 80.0 1.9 3.8e-22 79.4 1.9 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY07088.1 - 0.0011 18.5 1.6 0.0028 17.2 0.5 2.2 2 1 0 2 2 2 1 Sulfotransferase domain Sec5 PF15469.6 CBY07088.1 - 0.021 14.6 0.0 0.052 13.4 0.0 1.8 1 1 0 1 1 1 0 Exocyst complex component Sec5 Amino_oxidase PF01593.24 CBY07089.1 - 2e-75 254.8 0.0 3e-75 254.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CBY07089.1 - 1.1e-09 38.4 0.2 4.5e-09 36.4 0.1 2.0 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBY07089.1 - 1.2e-08 34.6 0.0 1.3e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBY07089.1 - 4e-06 26.3 0.3 0.0032 16.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBY07089.1 - 8.8e-05 21.4 0.2 0.00059 18.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 CBY07089.1 - 0.00014 21.2 0.0 0.0026 17.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CBY07089.1 - 0.00015 21.5 1.6 0.0002 21.1 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CBY07089.1 - 0.00036 19.8 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CBY07089.1 - 0.00096 19.7 0.5 0.0026 18.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBY07089.1 - 0.002 18.1 0.2 0.45 10.5 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CBY07089.1 - 0.0037 16.4 1.0 0.014 14.5 0.2 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein zf-CW PF07496.15 CBY07089.1 - 0.0044 17.0 0.7 0.0044 17.0 0.7 2.2 2 0 0 2 2 1 1 CW-type Zinc Finger FAD_oxidored PF12831.7 CBY07089.1 - 0.0046 16.3 0.3 0.009 15.4 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBY07089.1 - 0.0064 15.6 0.4 0.0097 15.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CBY07089.1 - 0.036 13.2 0.6 0.065 12.3 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CBY07089.1 - 0.036 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SWIRM PF04433.17 CBY07089.1 - 0.098 13.0 0.0 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 SWIRM domain Lipase_GDSL PF00657.22 CBY07090.1 - 3.5e-07 30.4 0.0 7.7e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase V-ATPase_H_C PF11698.8 CBY07090.1 - 0.028 14.5 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 0 V-ATPase subunit H Chromo PF00385.24 CBY07091.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain VWD PF00094.25 CBY07092.1 - 1.8e-13 51.1 1.9 8.5e-13 48.9 1.9 2.0 1 1 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 CBY07092.1 - 2e-12 47.3 1.2 2e-12 47.3 1.2 2.5 2 0 0 2 2 2 1 C8 domain Somatomedin_B PF01033.17 CBY07092.1 - 4.6e-06 26.9 20.1 4.6e-06 26.9 20.1 3.9 3 1 0 3 3 3 1 Somatomedin B domain TIL PF01826.17 CBY07092.1 - 0.0058 16.9 7.8 0.0058 16.9 7.8 3.6 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Sulfotransfer_1 PF00685.27 CBY07093.1 - 2.5e-19 69.8 0.1 4.1e-19 69.1 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY07093.1 - 5.6e-10 40.0 0.7 8e-06 26.4 0.0 3.9 3 1 1 4 4 4 2 Sulfotransferase family Laminin_EGF PF00053.24 CBY07094.1 - 1.7e-65 216.9 233.0 2.6e-09 37.1 11.5 11.5 12 0 0 12 12 12 10 Laminin EGF domain Laminin_N PF00055.17 CBY07094.1 - 1.7e-31 109.7 0.1 1.7e-31 109.7 0.1 2.9 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 CBY07094.1 - 6.1e-11 42.4 0.0 1.6e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Laminin B (Domain IV) HS1_rep PF02218.15 CBY07094.1 - 2.9 8.3 7.9 13 6.2 0.2 3.7 4 0 0 4 4 4 0 Repeat in HS1/Cortactin Herpes_pp85 PF04637.12 CBY07096.1 - 0.14 10.6 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Exo_endo_phos_2 PF14529.6 CBY07097.1 - 0.0048 16.7 0.0 0.018 14.8 0.0 2.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TSP_1 PF00090.19 CBY07098.1 - 1.9 8.7 9.7 1.8 8.8 0.2 3.1 2 1 0 2 2 2 0 Thrombospondin type 1 domain BCDHK_Adom3 PF10436.9 CBY07100.1 - 3.2e-37 127.9 0.1 5.4e-37 127.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBY07100.1 - 1e-15 58.2 0.2 1.3e-14 54.6 0.0 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBY07100.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Citrate_synt PF00285.21 CBY07100.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain HATPase_c_2 PF13581.6 CBY07100.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain RabGAP-TBC PF00566.18 CBY07101.1 - 1.4e-09 37.9 2.3 1.1e-07 31.8 0.8 2.6 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Rhodanese PF00581.20 CBY07101.1 - 2.2e-07 31.3 0.0 3.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Antiterm PF03589.13 CBY07101.1 - 0.079 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Antitermination protein Scramblase PF03803.15 CBY07102.1 - 1.4e-78 263.2 0.4 1.6e-78 263.0 0.4 1.0 1 0 0 1 1 1 1 Scramblase PID PF00640.23 CBY07103.1 - 8.4e-13 48.5 2.3 1.2e-12 48.1 2.3 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 CBY07103.1 - 2.9e-05 24.2 0.6 4.1e-05 23.7 0.6 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 CBY07103.1 - 0.0024 17.7 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) UNC-93 PF05978.16 CBY07106.1 - 1.6e-35 122.1 6.7 1.6e-35 122.1 6.7 2.3 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CBY07106.1 - 7.7e-13 48.1 17.3 1.2e-12 47.5 17.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Kringle PF00051.18 CBY07107.1 - 9.4e-35 118.8 12.4 6.7e-21 74.4 0.8 2.2 2 0 0 2 2 2 2 Kringle domain fn2 PF00040.19 CBY07107.1 - 0.79 10.0 9.6 5.7 7.3 4.5 2.7 2 0 0 2 2 2 0 Fibronectin type II domain PALP PF00291.25 CBY07108.1 - 5.9e-65 219.6 0.0 6.7e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Kelch_1 PF01344.25 CBY07109.1 - 0.051 13.2 0.8 0.22 11.1 0.3 2.3 2 0 0 2 2 2 0 Kelch motif Lectin_C PF00059.21 CBY07110.1 - 1.2e-44 151.4 24.5 7.9e-18 65.2 1.6 5.3 5 0 0 5 5 5 4 Lectin C-type domain Chordopox_A33R PF05966.12 CBY07110.1 - 5.3e-06 25.8 2.7 0.0036 16.6 0.2 2.4 2 0 0 2 2 2 2 Chordopoxvirus A33R protein Trefoil PF00088.18 CBY07110.1 - 0.002 18.0 3.2 0.002 18.0 3.2 2.7 2 0 0 2 2 2 1 Trefoil (P-type) domain SKG6 PF08693.10 CBY07110.1 - 0.53 9.7 3.0 0.94 8.9 3.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF5079 PF16882.5 CBY07111.1 - 0.016 15.1 1.5 0.018 15.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) Cadherin PF00028.17 CBY07112.1 - 4e-28 97.7 0.0 8.5e-09 35.8 0.0 4.4 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.12 CBY07112.1 - 0.00015 21.5 0.0 2.9 7.8 0.0 3.4 3 0 0 3 3 3 2 Cadherin-like RSN1_TM PF13967.6 CBY07112.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Protocadherin PF08374.11 CBY07112.1 - 0.04 13.9 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Protocadherin DapB_N PF01113.20 CBY07112.1 - 0.068 13.3 1.4 0.13 12.4 0.2 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF3637 PF12337.8 CBY07112.1 - 0.096 13.0 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) zf-C4 PF00105.18 CBY07114.1 - 2.3e-27 95.2 12.2 4.4e-27 94.3 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY07114.1 - 1.7e-11 44.1 3.4 3.2e-11 43.2 3.4 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TPR_2 PF07719.17 CBY07116.1 - 8.5e-15 53.6 7.3 0.00015 21.6 0.0 7.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY07116.1 - 1.9e-14 52.6 0.7 0.00026 21.0 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY07116.1 - 2.4e-12 47.2 3.1 0.0027 18.2 0.0 5.2 4 3 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY07116.1 - 1.3e-10 40.7 1.8 0.0046 16.7 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY07116.1 - 6.6e-10 39.5 3.3 0.001 19.7 0.0 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY07116.1 - 4.2e-09 36.6 6.6 4.4e-05 23.7 0.0 4.9 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY07116.1 - 1e-08 34.9 0.7 0.015 15.7 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY07116.1 - 7.8e-08 32.5 11.8 1.4 9.9 0.0 7.3 2 2 5 7 7 7 2 Tetratricopeptide repeat TPR_21 PF09976.9 CBY07116.1 - 3.5e-07 30.1 3.6 0.015 15.0 0.0 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 CBY07116.1 - 4.4e-07 29.5 0.0 0.019 14.6 0.0 3.5 3 0 0 3 3 3 2 TPR repeat ANAPC3 PF12895.7 CBY07116.1 - 1.5e-05 25.1 0.9 0.2 11.9 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBY07116.1 - 2.6e-05 23.9 1.3 0.029 14.4 0.0 4.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY07116.1 - 0.0052 16.2 1.0 0.08 12.3 0.1 2.7 2 1 1 3 3 3 1 MalT-like TPR region TPR_3 PF07720.12 CBY07116.1 - 0.012 15.6 0.0 5.6 7.1 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 CBY07116.1 - 0.016 14.2 0.0 4 6.2 0.0 2.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CBY07116.1 - 0.029 15.0 4.8 38 5.2 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY07116.1 - 0.041 13.8 1.2 4.7 7.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CBY07116.1 - 0.066 12.6 0.1 0.68 9.3 0.0 2.5 1 1 1 2 2 2 0 Coatomer epsilon subunit Lectin_C PF00059.21 CBY07119.1 - 0.033 14.9 0.1 11 6.8 0.0 2.5 2 0 0 2 2 2 0 Lectin C-type domain G8 PF10162.9 CBY07120.1 - 2.5e-49 166.5 0.0 1.9e-30 105.5 0.0 2.7 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 CBY07120.1 - 1.7e-42 143.3 41.4 2.2e-08 34.1 0.8 10.4 9 0 0 9 9 9 8 IPT/TIG domain Zona_pellucida PF00100.23 CBY07120.1 - 3.7e-32 112.1 5.3 1.5e-31 110.2 2.2 3.3 3 0 0 3 3 3 1 Zona pellucida-like domain Beta_helix PF13229.6 CBY07120.1 - 6.3e-08 32.6 17.1 0.0057 16.5 3.4 5.4 2 2 2 4 4 4 4 Right handed beta helix region Kringle PF00051.18 CBY07120.1 - 2.5e-07 30.9 1.0 2.5e-07 30.9 1.0 2.5 2 0 0 2 2 2 1 Kringle domain EGF_3 PF12947.7 CBY07120.1 - 3.4e-05 23.9 9.8 3.4e-05 23.9 9.8 2.7 3 0 0 3 3 3 1 EGF domain Choline_kinase PF01633.20 CBY07121.1 - 1.5e-17 63.9 0.2 1.1e-16 61.0 0.3 2.1 2 1 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 CBY07121.1 - 3.1e-10 39.9 0.0 4.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CBY07121.1 - 4.1e-07 30.2 0.1 1e-06 28.9 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CBY07121.1 - 0.0015 17.4 0.8 0.0025 16.8 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 CBY07121.1 - 0.011 15.1 0.2 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 CBY07121.1 - 0.081 12.3 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.30 CBY07122.1 - 1.8e-25 89.2 0.2 1.3e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 C2 domain Thyroglobulin_1 PF00086.18 CBY07123.1 - 4.8e-05 23.0 0.9 4.8e-05 23.0 0.9 3.2 3 0 0 3 3 3 1 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.9 CBY07123.1 - 0.0014 18.9 3.0 0.98 9.8 0.9 3.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Cys_rich_CWC PF14375.6 CBY07123.1 - 0.49 10.8 3.7 21 5.6 1.0 3.0 2 0 0 2 2 2 0 Cysteine-rich CWC zf-C4 PF00105.18 CBY07124.1 - 1.4e-22 79.9 11.1 1.4e-22 79.9 11.1 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) SNN_cytoplasm PF09051.10 CBY07124.1 - 0.1 12.4 2.1 34 4.4 0.1 3.3 3 0 0 3 3 3 0 Stannin cytoplasmic zf-RING_2 PF13639.6 CBY07124.1 - 7.8 6.9 10.8 65 4.0 10.8 2.4 1 1 0 1 1 1 0 Ring finger domain Pkinase PF00069.25 CBY07129.1 - 6.3e-68 229.0 0.0 8.8e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY07129.1 - 1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY07129.1 - 5.7e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY07129.1 - 9.1e-05 21.6 9.3 0.0016 17.4 9.3 2.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY07129.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY07129.1 - 0.051 12.6 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CBY07129.1 - 0.18 11.2 0.1 0.65 9.3 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spo7 PF03907.13 CBY07130.1 - 0.14 11.6 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Spo7-like protein DUF2700 PF10912.8 CBY07130.1 - 0.41 10.7 10.7 18 5.3 10.7 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2700) DUF4010 PF13194.6 CBY07130.1 - 2.4 7.8 12.4 1.1e+02 2.4 12.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) DUF3439 PF11921.8 CBY07131.1 - 7.4 6.6 21.1 0.11 12.5 5.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3439) adh_short PF00106.25 CBY07132.1 - 3.4e-33 114.8 1.4 4.6e-33 114.3 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY07132.1 - 1.6e-26 93.3 1.1 2.3e-26 92.8 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Phospholip_A2_1 PF00068.19 CBY07132.1 - 3.5e-18 66.1 9.1 1.1e-17 64.5 9.1 1.8 1 0 0 1 1 1 1 Phospholipase A2 KR PF08659.10 CBY07132.1 - 3.4e-09 36.9 0.1 5.2e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 CBY07132.1 - 0.0049 16.2 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY07132.1 - 0.038 13.5 0.1 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GOLGA2L5 PF15070.6 CBY07133.1 - 0.0011 17.8 9.7 0.0016 17.2 9.7 1.4 1 1 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Leuk-A4-hydro_C PF09127.11 CBY07133.1 - 0.0034 17.5 1.1 1.6 8.8 0.1 2.2 2 0 0 2 2 2 2 Leukotriene A4 hydrolase, C-terminal HALZ PF02183.18 CBY07133.1 - 0.012 15.8 0.6 0.012 15.8 0.6 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper Spc29 PF17082.5 CBY07133.1 - 0.039 13.8 6.0 0.067 13.0 5.9 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 Allexi_40kDa PF05549.11 CBY07133.1 - 0.065 12.7 1.1 0.082 12.4 1.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4407 PF14362.6 CBY07133.1 - 0.28 10.5 6.2 0.37 10.1 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cauli_AT PF03233.13 CBY07133.1 - 0.44 10.5 5.0 0.32 10.9 3.1 1.7 1 1 0 1 1 1 0 Aphid transmission protein Atg14 PF10186.9 CBY07133.1 - 0.45 9.5 12.9 1.5 7.9 12.9 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF745 PF05335.13 CBY07133.1 - 0.68 9.6 3.5 1.7 8.4 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) FapA PF03961.13 CBY07133.1 - 0.75 8.3 9.4 1.9 7.0 9.4 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 CBY07133.1 - 0.87 8.8 8.6 0.088 12.0 3.5 1.7 2 0 0 2 2 2 0 TMPIT-like protein IATP PF04568.12 CBY07133.1 - 1 9.8 8.5 5.1 7.6 6.3 2.2 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP OmpH PF03938.14 CBY07133.1 - 1.3 9.4 14.5 0.11 12.8 8.6 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1640 PF07798.11 CBY07133.1 - 1.3 9.0 10.8 1.9 8.5 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Swi5 PF07061.11 CBY07133.1 - 2.1 8.5 8.9 0.44 10.7 1.1 2.8 3 0 0 3 3 3 0 Swi5 HIP1_clath_bdg PF16515.5 CBY07133.1 - 2.8 8.6 13.0 0.35 11.5 6.5 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SLATT_1 PF18181.1 CBY07133.1 - 5 7.1 7.2 13 5.8 1.3 2.4 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DUF3450 PF11932.8 CBY07133.1 - 8 5.7 14.6 0.12 11.6 6.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) adh_short PF00106.25 CBY07135.1 - 1.5e-51 174.6 1.9 1.9e-51 174.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY07135.1 - 1.3e-36 126.4 2.3 1.7e-36 125.9 2.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY07135.1 - 3.3e-13 49.9 0.5 5e-13 49.4 0.5 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 CBY07135.1 - 0.0037 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY07135.1 - 0.027 14.0 0.3 0.044 13.2 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3456 PF11938.8 CBY07136.1 - 9.6e-06 26.2 2.9 0.00024 21.6 0.6 2.4 1 1 0 2 2 2 2 TLR4 regulator and MIR-interacting MSAP adh_short PF00106.25 CBY07137.1 - 1.1e-51 175.1 0.4 1.4e-51 174.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY07137.1 - 4.9e-35 121.2 0.2 6.6e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY07137.1 - 7e-11 42.4 0.3 9.9e-11 41.9 0.3 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 CBY07137.1 - 0.00047 19.6 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY07137.1 - 0.032 13.7 0.2 0.055 12.9 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family YccV-like PF08755.11 CBY07137.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like Laminin_G_3 PF13385.6 CBY07138.1 - 0.016 15.4 14.1 1.1 9.4 0.2 4.9 5 0 0 5 5 5 0 Concanavalin A-like lectin/glucanases superfamily DUF2850 PF11012.8 CBY07138.1 - 0.037 14.3 0.0 19 5.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) Carb_anhydrase PF00194.21 CBY07144.1 - 3.5e-58 197.1 0.0 4.7e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RA PF00788.23 CBY07144.1 - 0.009 16.6 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Thioredoxin PF00085.20 CBY07145.1 - 1.8e-63 211.0 0.0 1.5e-30 105.2 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 CBY07145.1 - 3e-11 43.7 0.8 0.0022 18.4 0.0 4.8 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY07145.1 - 2.2e-09 37.5 0.0 0.11 12.9 0.0 4.5 3 2 0 4 4 4 3 Thioredoxin-like OST3_OST6 PF04756.13 CBY07145.1 - 2.9e-08 33.4 0.0 0.0012 18.3 0.0 2.6 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CBY07145.1 - 1.3e-07 31.7 0.0 0.00052 20.2 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CBY07145.1 - 1.5e-05 24.9 0.1 0.016 15.1 0.0 3.0 4 0 0 4 4 4 2 AhpC/TSA family TraF PF13728.6 CBY07145.1 - 0.00049 20.0 0.0 0.31 10.8 0.0 3.3 3 1 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 CBY07145.1 - 0.0014 18.5 0.0 1.5 8.7 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CBY07145.1 - 0.0016 18.7 0.6 1.3 9.2 0.1 4.0 3 2 1 4 4 4 1 Thioredoxin Thioredoxin_3 PF13192.6 CBY07145.1 - 0.0031 17.5 0.0 3.9 7.6 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_5 PF13743.6 CBY07145.1 - 0.0037 17.0 0.0 9.6 5.8 0.0 4.2 3 2 2 5 5 5 1 Thioredoxin Thioredoxin_9 PF14595.6 CBY07145.1 - 0.042 13.6 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin HyaE PF07449.11 CBY07145.1 - 0.13 12.2 0.0 13 5.8 0.0 3.0 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE adh_short_C2 PF13561.6 CBY07146.1 - 1.8e-44 152.1 0.1 2.2e-44 151.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY07146.1 - 1.7e-42 145.1 2.2 2.2e-42 144.8 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY07146.1 - 2.3e-13 50.4 0.3 3.2e-13 50.0 0.3 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 CBY07146.1 - 8.1e-05 23.1 0.2 0.00016 22.2 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 CBY07146.1 - 0.0018 18.5 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CBY07146.1 - 0.0021 17.3 0.3 0.01 15.0 0.3 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NanE PF04131.14 CBY07146.1 - 0.017 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase 3HCDH_N PF02737.18 CBY07146.1 - 0.034 14.0 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY07146.1 - 0.055 12.9 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_C1 PF00112.23 CBY07148.1 - 1.9e-43 149.1 3.2 2.6e-43 148.7 3.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CBY07148.1 - 0.0068 15.2 1.1 0.011 14.6 1.1 1.2 1 0 0 1 1 1 1 Peptidase C1-like family p450 PF00067.22 CBY07150.1 - 2.3e-26 92.6 0.1 3.1e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 CUB PF00431.20 CBY07154.1 - 0.00068 20.0 0.1 0.0014 19.0 0.1 1.6 1 0 0 1 1 1 1 CUB domain LRR_8 PF13855.6 CBY07156.1 - 5.3e-13 48.5 4.6 7.3e-06 25.7 0.8 2.8 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBY07156.1 - 9.5e-11 41.8 4.5 7.5e-06 26.2 0.3 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY07156.1 - 9.1e-06 25.5 7.8 1.7 9.5 0.0 4.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 CBY07156.1 - 0.004 17.1 2.7 14 6.1 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich repeat DUF2116 PF09889.9 CBY07156.1 - 0.54 10.3 2.0 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) LPAM_1 PF08139.12 CBY07156.1 - 6.5 7.5 7.0 12 6.6 7.0 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site LEM PF03020.15 CBY07157.1 - 1.2e-09 37.6 1.3 1.1e-05 24.9 0.0 2.5 3 0 0 3 3 3 2 LEM domain LETM1 PF07766.13 CBY07157.1 - 0.17 11.2 5.1 0.34 10.2 0.1 2.0 1 1 1 2 2 2 0 LETM1-like protein Pyr_redox_2 PF07992.14 CBY07158.1 - 4.5e-66 223.1 9.0 9.1e-66 222.1 6.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBY07158.1 - 5.3e-41 139.3 0.3 5.3e-41 139.3 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBY07158.1 - 1.7e-20 73.3 7.9 7.1e-19 68.2 1.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CBY07158.1 - 5.3e-09 35.9 0.3 5.3e-09 35.9 0.3 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBY07158.1 - 1.7e-07 30.8 5.1 0.00072 18.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBY07158.1 - 9.4e-07 28.2 0.3 9.4e-07 28.2 0.3 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CBY07158.1 - 1.5e-06 28.3 4.8 3e-05 24.2 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBY07158.1 - 2.7e-06 26.7 0.9 2.7e-06 26.7 0.9 2.8 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 CBY07158.1 - 3e-06 26.2 10.9 0.002 16.9 0.9 3.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 CBY07158.1 - 3.6e-06 26.8 10.3 0.0029 17.2 0.0 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CBY07158.1 - 4e-05 22.9 0.4 0.022 13.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.15 CBY07158.1 - 0.00018 20.2 0.9 0.00037 19.2 0.3 1.7 1 1 1 2 2 2 1 Malate:quinone oxidoreductase (Mqo) AlaDh_PNT_C PF01262.21 CBY07158.1 - 0.0024 17.2 6.1 0.26 10.6 0.2 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CBY07158.1 - 0.0025 17.1 2.2 0.017 14.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CBY07158.1 - 0.02 14.1 11.3 0.15 11.3 0.5 3.5 4 0 0 4 4 4 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 CBY07158.1 - 0.49 9.9 5.2 9.2 5.8 0.2 3.6 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 CBY07158.1 - 3.1 6.8 6.1 2.4 7.1 0.4 3.0 3 1 1 4 4 4 0 Lycopene cyclase protein UPF0016 PF01169.19 CBY07159.1 - 8.2e-39 131.8 23.1 2.4e-20 72.6 9.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 CBY07159.1 - 1.5e-05 24.8 6.0 0.00022 21.0 0.1 2.3 2 0 0 2 2 2 1 Putative manganese efflux pump TerC PF03741.16 CBY07159.1 - 0.033 13.9 8.6 0.051 13.3 0.2 2.3 2 0 0 2 2 2 0 Integral membrane protein TerC family Phage_holin_3_6 PF07332.11 CBY07159.1 - 0.063 13.3 0.1 0.063 13.3 0.1 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MMU163 PF17119.5 CBY07159.1 - 0.078 12.1 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis CytochromB561_N PF09786.9 CBY07159.1 - 0.09 11.8 0.5 0.15 11.0 0.2 1.4 1 1 1 2 2 2 0 Cytochrome B561, N terminal FixQ PF05545.11 CBY07159.1 - 0.094 12.7 0.3 0.094 12.7 0.3 2.9 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF4131 PF13567.6 CBY07159.1 - 0.33 10.6 1.9 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_U4 PF03419.13 CBY07159.1 - 4 6.7 8.9 0.099 11.9 0.4 2.0 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Mito_carr PF00153.27 CBY07161.1 - 2.8e-43 145.8 2.8 4.5e-14 52.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PEHE PF15275.6 CBY07162.1 - 0.01 16.4 1.0 0.01 16.4 1.0 4.8 3 2 1 4 4 4 0 PEHE domain PP2C PF00481.21 CBY07163.1 - 3.1e-44 151.5 0.0 3.8e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY07163.1 - 4.3e-08 33.1 0.0 7.7e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C UCH PF00443.29 CBY07163.1 - 0.056 12.9 0.1 0.087 12.3 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase FAM76 PF16046.5 CBY07164.1 - 0.005 16.2 8.3 0.005 16.2 8.3 3.3 3 1 1 4 4 4 1 FAM76 protein Sulfotransfer_2 PF03567.14 CBY07165.1 - 6.3e-11 42.7 0.2 1.8e-10 41.2 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family LAP1C PF05609.12 CBY07167.1 - 0.081 12.0 3.4 0.083 12.0 3.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) KCNQ_channel PF03520.14 CBY07168.1 - 4.4e-15 56.0 0.3 5.7e-15 55.7 0.3 1.3 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel PRD PF00874.20 CBY07168.1 - 0.016 15.5 0.1 0.065 13.5 0.1 2.0 1 1 1 2 2 2 0 PRD domain Ion_trans PF00520.31 CBY07169.1 - 4.2e-24 85.1 9.4 5.4e-24 84.8 9.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY07169.1 - 4.9e-12 45.6 7.9 4.9e-12 45.6 7.9 2.7 3 0 0 3 3 3 1 Ion channel DUF4231 PF14015.6 CBY07169.1 - 0.011 16.2 0.2 2.5 8.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SpoIIM PF01944.17 CBY07169.1 - 0.044 13.8 5.0 0.17 11.9 5.1 2.0 1 1 0 1 1 1 0 Stage II sporulation protein M Ras PF00071.22 CBY07170.1 - 5.8e-22 78.0 0.0 6.1e-21 74.7 0.0 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBY07170.1 - 0.00051 20.2 0.0 0.03 14.5 0.0 2.7 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBY07170.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.21 CBY07170.1 - 0.13 11.7 0.0 0.58 9.6 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family UQ_con PF00179.26 CBY07171.1 - 1.7e-19 69.9 0.0 2.7e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Lipase_3 PF01764.25 CBY07171.1 - 1.7e-16 60.4 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Gelsolin PF00626.22 CBY07172.1 - 0.096 12.6 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Gelsolin repeat Sld3_N PF18523.1 CBY07172.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Sld3 N-terminal domain R3H PF01424.22 CBY07173.1 - 9.5e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain NCBP3 PF10309.9 CBY07173.1 - 2.3e-05 24.2 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 CBY07173.1 - 6e-05 23.0 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain PAM2 PF07145.15 CBY07173.1 - 0.19 11.5 12.3 0.071 12.8 2.2 4.0 4 0 0 4 4 4 0 Ataxin-2 C-terminal region JIP_LZII PF16471.5 CBY07174.1 - 0.01 16.0 0.8 0.019 15.1 0.6 1.7 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Gp-FAR-1 PF05823.12 CBY07174.1 - 0.018 15.4 1.1 0.024 15.0 0.2 1.6 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HEPN_Toprim_N PF18871.1 CBY07174.1 - 0.025 14.5 2.6 0.44 10.4 1.1 2.0 1 1 1 2 2 2 0 HEPN/Toprim N-terminal domain 1 DUF16 PF01519.16 CBY07174.1 - 0.035 14.6 0.8 0.074 13.5 0.8 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Tropomyosin_1 PF12718.7 CBY07174.1 - 0.27 11.4 4.9 0.082 13.1 2.2 1.5 2 0 0 2 2 2 0 Tropomyosin like Polysacc_synt_C PF14667.6 CBY07175.1 - 3.6 7.7 12.9 16 5.6 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain CIA30 PF08547.12 CBY07178.1 - 6.6e-27 94.5 0.2 8.3e-27 94.2 0.2 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 CBY07178.1 - 0.0013 18.7 0.4 0.0021 18.1 0.2 1.3 1 1 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain MFS_1 PF07690.16 CBY07179.1 - 9.4e-34 116.9 44.2 1.9e-28 99.4 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phospholip_A2_1 PF00068.19 CBY07180.1 - 5.2e-09 36.6 3.9 0.0011 19.4 0.0 2.7 3 0 0 3 3 3 2 Phospholipase A2 DUF2325 PF10087.9 CBY07181.1 - 0.076 13.1 0.2 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF4599 PF15371.6 CBY07181.1 - 0.27 11.8 2.6 6.2 7.4 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4599) THOC7 PF05615.13 CBY07181.1 - 0.6 10.4 17.9 0.72 10.1 6.0 2.6 2 1 1 3 3 3 0 Tho complex subunit 7 TPD52 PF04201.15 CBY07181.1 - 0.84 9.2 9.4 0.13 11.9 4.3 2.2 2 1 0 2 2 2 0 Tumour protein D52 family TDA11 PF17084.5 CBY07181.1 - 1.1 8.1 4.6 1.7 7.5 4.6 1.2 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 Uso1_p115_C PF04871.13 CBY07181.1 - 2.2 8.7 18.3 0.13 12.6 10.3 2.5 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-H PF05837.12 CBY07181.1 - 5.4 7.5 10.3 1.4 9.3 6.7 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Aldo_ket_red PF00248.21 CBY07182.1 - 4.3e-22 78.7 0.0 1.6e-20 73.5 0.0 2.2 1 1 1 2 2 2 1 Aldo/keto reductase family MerR_2 PF13591.6 CBY07182.1 - 0.069 13.0 0.2 2.2 8.2 0.2 2.6 2 0 0 2 2 2 0 MerR HTH family regulatory protein FlxA PF14282.6 CBY07182.1 - 0.25 11.3 3.7 0.64 10.0 3.7 1.7 1 0 0 1 1 1 0 FlxA-like protein FIN1 PF17300.2 CBY07182.1 - 0.62 9.5 4.1 1.3 8.5 4.1 1.4 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Zona_pellucida PF00100.23 CBY07183.1 - 1.5e-18 67.6 0.1 1.5e-18 67.6 0.1 1.8 2 0 0 2 2 2 1 Zona pellucida-like domain Sushi PF00084.20 CBY07183.1 - 0.0058 17.2 7.4 1.7 9.3 3.3 2.8 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Kunitz_BPTI PF00014.23 CBY07184.1 - 1.2e-22 79.9 16.7 9.1e-16 57.8 0.4 2.2 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Collagen PF01391.18 CBY07185.1 - 0.0036 17.0 9.6 0.028 14.2 9.6 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF1816 PF08846.10 CBY07186.1 - 0.085 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) DUF3719 PF12516.8 CBY07187.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Met_10 PF02475.16 CBY07189.1 - 1.4e-41 142.5 0.0 2.7e-41 141.5 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 CBY07189.1 - 0.002 18.0 0.0 0.0079 16.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY07189.1 - 0.0035 18.0 0.0 0.024 15.3 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBY07189.1 - 0.011 15.3 0.1 0.11 12.0 0.0 2.5 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CBY07189.1 - 0.035 13.7 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 CBY07189.1 - 0.072 13.7 0.0 1.1 9.9 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain 14-3-3 PF00244.20 CBY07190.1 - 0.04 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 14-3-3 protein Met_10 PF02475.16 CBY07193.1 - 8.2e-42 143.2 0.1 1.4e-41 142.4 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 CBY07193.1 - 0.0023 18.6 0.0 0.015 16.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY07193.1 - 0.0035 18.0 0.0 0.18 12.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CBY07193.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 CBY07193.1 - 0.022 14.3 0.1 0.048 13.2 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 CBY07193.1 - 0.023 14.5 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 CBY07193.1 - 0.049 13.7 0.0 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase 14-3-3 PF00244.20 CBY07194.1 - 0.042 13.3 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein DUF2540 PF10802.8 CBY07194.1 - 0.087 12.9 0.5 0.92 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) His_Phos_1 PF00300.22 CBY07195.1 - 4e-34 118.0 0.1 4.4e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aa_trans PF01490.18 CBY07196.1 - 1.9e-15 56.5 18.9 3.6e-15 55.6 18.9 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein YbjM PF11045.8 CBY07196.1 - 0.0071 16.5 6.8 0.0088 16.2 2.3 2.4 1 1 1 2 2 2 1 Putative inner membrane protein of Enterobacteriaceae AmpE PF17113.5 CBY07196.1 - 0.068 12.5 0.4 0.11 11.8 0.4 1.2 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE Trp_DMAT PF11991.8 CBY07197.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.0 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase Calsequestrin PF01216.17 CBY07197.1 - 0.073 12.1 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin RRM_1 PF00076.22 CBY07200.1 - 2.8e-30 103.9 0.1 8.6e-20 70.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY07200.1 - 1.1e-05 25.2 0.0 0.01 15.7 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CBY07200.1 - 4.2e-05 23.6 0.0 0.39 10.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CBY07200.1 - 0.01 16.1 0.2 2.9 8.1 0.3 2.7 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 CBY07200.1 - 0.044 13.8 0.1 0.47 10.5 0.2 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif F-box-like PF12937.7 CBY07201.1 - 1.9e-06 27.7 0.1 3.9e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like BTK PF00779.19 CBY07201.1 - 1e-05 25.2 0.5 2.1e-05 24.2 0.5 1.6 1 0 0 1 1 1 1 BTK motif F-box PF00646.33 CBY07201.1 - 0.00046 20.0 0.1 0.0012 18.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain DEK_C PF08766.11 CBY07203.1 - 9.3e-11 41.5 0.0 2.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain NOT2_3_5 PF04153.18 CBY07203.1 - 0.12 12.4 0.4 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family Phospholip_A2_1 PF00068.19 CBY07204.1 - 4.1e-16 59.4 4.0 4.1e-16 59.4 4.0 1.8 2 0 0 2 2 2 1 Phospholipase A2 Connexin PF00029.19 CBY07205.1 - 5.7e-56 189.9 5.3 3.2e-55 187.5 5.3 1.8 1 1 0 1 1 1 1 Connexin DUF2207 PF09972.9 CBY07205.1 - 0.0022 16.8 3.4 0.16 10.7 0.2 2.2 1 1 1 2 2 2 2 Predicted membrane protein (DUF2207) DndB PF14072.6 CBY07205.1 - 0.0023 17.2 0.1 0.0035 16.6 0.1 1.2 1 0 0 1 1 1 1 DNA-sulfur modification-associated FCH PF00611.23 CBY07205.1 - 0.025 14.8 4.8 0.053 13.8 4.8 1.6 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 CBY07205.1 - 0.11 11.8 2.4 0.2 11.0 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Orf78 PF06024.12 CBY07205.1 - 0.18 12.1 0.0 0.18 12.1 0.0 2.9 3 1 1 4 4 4 0 Orf78 (ac78) DUF5401 PF17380.2 CBY07205.1 - 0.79 7.7 13.2 1 7.3 13.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Peptidase_S49_N PF08496.10 CBY07205.1 - 3.3 7.8 13.2 2.3 8.3 7.9 2.3 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Sulfotransfer_1 PF00685.27 CBY07206.1 - 5e-09 36.0 0.7 8.6e-09 35.3 0.1 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY07206.1 - 1.2e-05 25.8 0.2 6.8e-05 23.3 0.0 2.2 3 0 0 3 3 3 1 Sulfotransferase family GerD PF17898.1 CBY07206.1 - 0.011 15.7 1.2 0.028 14.4 0.2 2.3 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF573 PF04504.14 CBY07206.1 - 0.05 14.3 0.6 0.15 12.8 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Uteroglobin PF01099.17 CBY07206.1 - 0.15 12.4 1.0 0.41 11.0 1.0 1.7 1 0 0 1 1 1 0 Uteroglobin family Arg_decarbox_C PF17944.1 CBY07206.1 - 0.73 10.4 3.0 1.3 9.7 1.6 2.1 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension KNOX2 PF03791.13 CBY07206.1 - 0.79 9.3 4.9 1.9 8.1 1.9 2.6 2 0 0 2 2 2 0 KNOX2 domain Aldose_epim PF01263.20 CBY07207.1 - 1.8e-49 168.7 0.2 2.3e-49 168.3 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Aldose_epim PF01263.20 CBY07208.1 - 2.3e-19 69.9 0.0 2.4e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Trypsin PF00089.26 CBY07211.1 - 6.8e-38 130.7 0.1 6.8e-38 130.7 0.1 1.7 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 CBY07211.1 - 9.3e-06 26.0 0.0 2.7e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) UPAR_LY6_2 PF16975.5 CBY07211.1 - 0.0017 18.5 10.1 0.0017 18.5 10.1 1.7 2 0 0 2 2 2 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Trypsin_2 PF13365.6 CBY07211.1 - 0.076 13.9 0.0 0.23 12.3 0.0 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain Sugar_tr PF00083.24 CBY07212.1 - 0.33 9.8 0.1 0.32 9.8 0.1 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Aldo_ket_red PF00248.21 CBY07215.1 - 1.8e-05 24.1 0.3 4.2e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family Trypsin PF00089.26 CBY07216.1 - 4.2e-57 193.5 0.6 4.9e-57 193.3 0.6 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY07216.1 - 1.2e-05 26.2 0.0 2.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY07216.1 - 0.0039 17.6 0.1 0.0098 16.3 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Spermine_synth PF01564.17 CBY07217.1 - 1e-25 90.3 0.0 1.3e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CBY07217.1 - 6.5e-09 35.5 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_12 PF08242.12 CBY07217.1 - 0.00068 20.3 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Frag1 PF10277.9 CBY07219.1 - 7e-21 74.8 17.6 8.6e-21 74.5 17.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family HOK_GEF PF01848.16 CBY07219.1 - 0.051 13.0 0.3 0.051 13.0 0.3 2.2 2 0 0 2 2 2 0 Hok/gef family MSC PF09402.10 CBY07219.1 - 0.14 11.6 2.4 0.16 11.4 0.6 1.7 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain DUF423 PF04241.15 CBY07219.1 - 1.8 8.8 6.5 0.62 10.3 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF423) DUF4131 PF13567.6 CBY07219.1 - 4 7.1 9.8 2.3 7.8 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CLZ PF16526.5 CBY07220.1 - 0.0054 17.1 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4200 PF13863.6 CBY07220.1 - 0.0086 16.5 0.5 0.018 15.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 CBY07220.1 - 0.093 12.9 1.3 0.098 12.8 0.1 1.5 2 0 0 2 2 2 0 Tropomyosin like DUF4446 PF14584.6 CBY07220.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) HrpB7 PF09486.10 CBY07220.1 - 0.17 12.3 0.2 0.32 11.4 0.1 1.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lin-8 PF03353.15 CBY07220.1 - 0.28 10.7 5.8 0.36 10.3 5.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TPPK_C PF12555.8 CBY07220.1 - 0.29 11.2 2.5 0.51 10.4 2.5 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF4690 PF15756.5 CBY07220.1 - 0.58 10.8 2.6 0.61 10.7 0.5 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage SKA1 PF07160.12 CBY07220.1 - 0.92 9.3 7.1 1.3 8.8 7.1 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Prominin PF05478.11 CBY07220.1 - 2.2 6.1 10.6 2.6 5.9 9.8 1.4 1 1 0 1 1 1 0 Prominin SKG6 PF08693.10 CBY07220.1 - 2.6 7.5 6.2 6.5 6.3 6.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Neur_chan_LBD PF02931.23 CBY07221.1 - 1.7e-30 106.1 4.9 2.7e-30 105.4 4.9 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY07221.1 - 0.083 12.9 7.9 0.071 13.2 6.0 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spore_Cse60 PF10957.8 CBY07221.1 - 0.11 12.5 0.1 17 5.6 0.0 2.8 2 0 0 2 2 2 0 Sporulation protein Cse60 Acyl-CoA_dh_1 PF00441.24 CBY07222.1 - 1.6e-38 132.3 0.2 2.6e-38 131.6 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY07222.1 - 7e-25 87.9 0.0 1.3e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY07222.1 - 1.7e-24 85.9 0.0 3.8e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY07222.1 - 8e-15 55.3 0.0 1.3e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C12orf66_like PF09404.10 CBY07222.1 - 2.3e-06 26.7 0.1 3.5e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like HpaB_N PF11794.8 CBY07222.1 - 0.041 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1175 PF06672.11 CBY07222.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) 7tm_1 PF00001.21 CBY07223.1 - 0.078 12.3 1.0 0.082 12.2 1.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Collagen PF01391.18 CBY07224.1 - 8.8e-14 51.0 88.4 2.8e-06 27.0 36.4 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) PfkB PF00294.24 CBY07225.1 - 7.2e-10 38.7 0.0 8.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Defb50 PF17546.2 CBY07225.1 - 0.011 15.6 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Beta defensin 50 Cortex-I_coil PF09304.10 CBY07225.1 - 0.2 11.9 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil zf-H2C2_2 PF13465.6 CBY07226.1 - 6.1e-19 67.5 21.7 2.2e-08 34.2 1.6 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY07226.1 - 2.8e-12 46.4 28.1 5.5e-06 26.5 0.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY07226.1 - 6.3e-09 35.9 25.3 0.0011 19.6 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY07226.1 - 1.9e-06 27.7 19.7 0.0028 17.6 2.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY07226.1 - 0.0012 18.5 0.4 0.0012 18.5 0.4 4.4 3 1 0 3 3 2 1 C2H2-type zinc-finger domain C1_4 PF07975.12 CBY07226.1 - 0.013 15.7 5.2 0.013 15.7 5.2 3.0 1 1 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 CBY07226.1 - 0.017 15.4 9.0 3.6 8.0 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY07226.1 - 0.088 13.2 0.3 0.088 13.2 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CBY07226.1 - 0.14 11.9 0.1 0.14 11.9 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zf_RING PF16744.5 CBY07226.1 - 0.3 11.2 15.5 0.24 11.5 0.7 3.2 1 1 0 2 2 2 0 KIAA1045 RING finger IBR PF01485.21 CBY07226.1 - 0.36 11.1 8.7 0.098 12.9 4.4 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2HC_2 PF13913.6 CBY07226.1 - 0.59 10.1 11.3 1.5 8.8 0.8 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 CBY07226.1 - 0.62 10.0 13.7 0.56 10.2 0.7 3.4 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_8 PF15909.5 CBY07226.1 - 0.93 9.8 8.8 3 8.2 1.9 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 CBY07226.1 - 2.4 8.6 12.7 20 5.7 6.3 3.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_9 PF14369.6 CBY07226.1 - 3.3 8.1 8.4 0.36 11.1 2.5 2.6 2 1 0 2 2 1 0 zinc-ribbon GAGA PF09237.11 CBY07226.1 - 3.7 7.4 6.3 12 5.8 3.3 2.5 1 1 1 2 2 2 0 GAGA factor Choline_kinase PF01633.20 CBY07227.1 - 6e-14 52.1 0.0 9.1e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY07227.1 - 3.1e-12 47.0 0.0 4.2e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY07227.1 - 4.4e-05 22.9 0.1 6.3e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 CBY07227.1 - 0.06 12.5 0.2 0.41 9.8 0.2 2.0 1 1 0 1 1 1 0 Fructosamine kinase PDZ PF00595.24 CBY07228.1 - 1.5e-12 47.7 0.1 9.5e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY07228.1 - 1.4e-11 44.0 1.0 1.1e-09 37.9 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY07228.1 - 1.7e-09 37.8 1.3 3.9e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Tup_N PF08581.10 CBY07228.1 - 0.0084 16.4 0.7 0.0084 16.4 0.7 2.1 2 0 0 2 2 2 1 Tup N-terminal MMR_HSR1_Xtn PF16897.5 CBY07228.1 - 0.028 14.4 0.2 0.26 11.3 0.1 2.6 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain SNARE_assoc PF09335.11 CBY07229.1 - 0.0081 16.6 0.3 0.012 16.1 0.3 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein Gly-zipper_Omp PF13488.6 CBY07229.1 - 0.011 15.7 14.0 0.022 14.7 14.0 1.5 1 0 0 1 1 1 0 Glycine zipper DUF456 PF04306.13 CBY07229.1 - 0.017 15.4 8.5 0.024 14.9 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.15 CBY07229.1 - 1.9 8.4 17.7 3.7 7.5 17.7 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Frag1 PF10277.9 CBY07230.1 - 3.7e-19 69.1 13.1 4.5e-19 68.8 13.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Frag1 PF10277.9 CBY07231.1 - 0.081 12.4 0.1 0.084 12.4 0.1 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family CBM_14 PF01607.24 CBY07232.1 - 1.2e-11 44.6 7.5 5.9e-11 42.4 6.7 2.1 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Gly-zipper_YMGG PF13441.6 CBY07234.1 - 0.0028 17.3 38.4 0.0043 16.7 32.9 2.4 1 1 1 2 2 2 2 YMGG-like Gly-zipper TraT PF05818.12 CBY07234.1 - 0.0054 16.4 5.4 0.0067 16.1 5.4 1.2 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.6 CBY07234.1 - 0.2 11.5 40.8 2.6 7.9 31.9 2.7 1 1 1 2 2 2 0 Glycine-zipper domain DUF533 PF04391.12 CBY07234.1 - 0.35 10.4 2.7 0.49 9.9 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF1269 PF06897.12 CBY07234.1 - 0.96 9.8 17.2 0.72 10.2 14.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) DUF726 PF05277.12 CBY07234.1 - 3.5 6.5 10.3 4.5 6.1 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Gly-zipper_Omp PF13488.6 CBY07234.1 - 4.1 7.5 42.1 17 5.5 38.1 2.9 1 1 1 2 2 2 0 Glycine zipper Keratin_2_head PF16208.5 CBY07234.1 - 4.7 7.3 16.5 6.3 6.9 16.5 1.1 1 0 0 1 1 1 0 Keratin type II head WD40 PF00400.32 CBY07235.1 - 1.2e-08 35.4 8.5 0.00026 21.7 0.3 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY07235.1 - 0.0002 21.6 0.0 2.5 8.5 0.0 4.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Sulfotransfer_1 PF00685.27 CBY07236.1 - 4.5e-18 65.7 0.2 4.5e-18 65.7 0.2 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY07236.1 - 6.6e-14 52.8 0.0 5.4e-05 23.7 0.0 3.4 2 1 1 3 3 3 3 Sulfotransferase family GDPD PF03009.17 CBY07237.1 - 3.2e-44 151.6 0.0 3.8e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4996 PF16387.5 CBY07237.1 - 0.0093 16.4 0.0 0.036 14.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function Folate_rec PF03024.14 CBY07240.1 - 1.5e-13 51.0 11.7 2.6e-13 50.2 11.7 1.3 1 0 0 1 1 1 1 Folate receptor family DUF3149 PF11346.8 CBY07240.1 - 0.034 13.8 0.8 0.066 12.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF1947 PF09183.10 CBY07240.1 - 0.056 13.7 1.9 1.1 9.6 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Orf78 PF06024.12 CBY07240.1 - 0.63 10.4 0.0 0.63 10.4 0.0 2.1 3 0 0 3 3 3 0 Orf78 (ac78) UQ_con PF00179.26 CBY07241.1 - 1.4e-21 76.7 0.0 2.7e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FKBP_N PF01346.18 CBY07241.1 - 0.16 12.9 3.1 0.47 11.4 3.1 1.8 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FlxA PF14282.6 CBY07241.1 - 2.6 8.1 6.9 4.5 7.3 2.7 2.5 2 0 0 2 2 2 0 FlxA-like protein AAA PF00004.29 CBY07242.1 - 3.4e-19 69.6 0.0 6.5e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CBY07242.1 - 5.7e-19 68.3 1.3 1.3e-18 67.2 0.2 2.2 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBY07242.1 - 8e-15 55.0 0.0 2e-10 40.7 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 CBY07242.1 - 1.4e-09 38.1 0.0 3.4e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CBY07242.1 - 9.1e-07 28.8 0.1 5e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CBY07242.1 - 1.9e-05 24.7 0.1 0.0085 16.1 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CBY07242.1 - 1.9e-05 24.6 0.1 0.00017 21.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CBY07242.1 - 2.1e-05 24.8 0.1 5e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 CBY07242.1 - 3.6e-05 23.8 0.0 7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY07242.1 - 4.1e-05 23.9 0.1 0.0031 17.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY07242.1 - 5.9e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CBY07242.1 - 7.3e-05 22.1 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CBY07242.1 - 8.7e-05 23.0 0.0 0.0071 16.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 CBY07242.1 - 0.00066 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 CBY07242.1 - 0.00076 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CBY07242.1 - 0.00094 19.2 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 CBY07242.1 - 0.00096 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 CBY07242.1 - 0.002 18.5 0.2 0.0093 16.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY07242.1 - 0.0042 17.6 0.2 0.021 15.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain DEAD PF00270.29 CBY07242.1 - 0.0043 16.8 0.2 0.029 14.1 0.2 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CBY07242.1 - 0.0045 16.7 0.0 0.015 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBY07242.1 - 0.0065 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CBY07242.1 - 0.0068 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PhoH PF02562.16 CBY07242.1 - 0.0096 15.4 0.1 0.041 13.3 0.1 2.0 1 1 0 1 1 1 1 PhoH-like protein Mg_chelatase PF01078.21 CBY07242.1 - 0.011 15.2 0.0 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CBY07242.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 CBY07242.1 - 0.039 13.7 0.0 6.3 6.5 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBY07242.1 - 0.044 13.5 0.1 0.33 10.7 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 CBY07242.1 - 0.046 13.1 0.1 2.5 7.5 0.0 2.3 1 1 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 CBY07242.1 - 0.059 13.8 0.3 0.36 11.2 0.0 2.3 2 1 0 2 2 2 0 RNA helicase DNA_pol3_gamma3 PF12169.8 CBY07242.1 - 0.11 12.5 0.1 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Kelch_1 PF01344.25 CBY07243.1 - 7.6e-05 22.2 0.7 0.00012 21.5 0.2 1.7 2 1 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 CBY07243.1 - 0.002 18.1 0.0 0.0051 16.8 0.0 1.7 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 CBY07243.1 - 0.0093 16.2 0.1 0.53 10.6 0.1 2.6 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY07243.1 - 0.013 15.5 0.2 0.022 14.7 0.0 1.5 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 CBY07243.1 - 0.2 12.0 1.3 2.2 8.7 1.3 2.2 1 1 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 CBY07243.1 - 0.52 10.3 2.5 0.35 10.9 0.5 2.0 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY07244.1 - 5.6e-22 77.3 5.7 7.9e-07 28.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CBY07244.1 - 1.6e-19 69.4 2.0 2.5e-08 33.9 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 CBY07244.1 - 4.6e-18 64.5 3.6 2.6e-09 36.5 0.1 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CBY07244.1 - 4.2e-15 55.5 3.5 1.5e-07 31.3 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY07244.1 - 4.5e-14 52.3 0.0 0.00021 21.5 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY07244.1 - 1.5e-11 43.8 8.8 8.3e-05 22.4 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Glyco_hydro_32N PF00251.20 CBY07244.1 - 0.095 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain DUF5427 PF10310.9 CBY07245.1 - 2.6 6.9 12.1 2.9 6.8 12.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Connexin PF00029.19 CBY07246.1 - 5e-55 186.8 5.0 6.3e-55 186.5 5.0 1.1 1 0 0 1 1 1 1 Connexin 7tm_1 PF00001.21 CBY07246.1 - 0.034 13.5 6.2 0.39 10.0 0.3 2.3 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4133 PF13571.6 CBY07246.1 - 0.055 13.8 1.1 1.7 9.1 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) N-SET PF11764.8 CBY07247.1 - 0.032 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N Peptidase_C14 PF00656.22 CBY07248.1 - 1.4e-16 61.2 0.0 2.9e-16 60.2 0.0 1.4 1 1 0 1 1 1 1 Caspase domain RhoGAP PF00620.27 CBY07249.1 - 1.9e-22 79.7 0.1 4.2e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain p450 PF00067.22 CBY07251.1 - 3e-53 181.2 0.2 6.9e-53 180.0 0.0 1.6 2 1 0 2 2 2 1 Cytochrome P450 PMP22_Claudin PF00822.20 CBY07252.1 - 1.8e-08 34.4 6.4 2.2e-08 34.2 6.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Peptidase_A24 PF01478.18 CBY07252.1 - 0.0098 16.3 4.8 0.022 15.2 4.8 1.5 1 1 0 1 1 1 1 Type IV leader peptidase family Dynein_light PF01221.18 CBY07252.1 - 0.041 14.2 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 Dynein light chain type 1 DUF1449 PF07290.11 CBY07252.1 - 0.13 11.9 0.4 0.17 11.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Prominin PF05478.11 CBY07252.1 - 0.99 7.3 5.1 1.3 6.9 5.1 1.1 1 0 0 1 1 1 0 Prominin ECF_trnsprt PF12822.7 CBY07252.1 - 5.5 7.1 9.0 0.78 9.8 5.4 1.4 2 0 0 2 2 2 0 ECF transporter, substrate-specific component SET PF00856.28 CBY07255.1 - 1.9e-13 51.2 0.0 2.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 SET domain CHB_HEX_C PF03174.13 CBY07256.1 - 0.093 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain UAA PF08449.11 CBY07257.1 - 1.4e-30 106.5 9.9 1.8e-30 106.2 9.9 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBY07257.1 - 1.7e-06 27.6 7.5 4e-06 26.4 7.5 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY07257.1 - 0.0017 18.5 8.8 0.0017 18.5 8.8 2.9 2 1 0 2 2 2 1 EamA-like transporter family Ninjurin PF04923.12 CBY07257.1 - 0.0093 15.9 3.0 0.34 10.8 0.3 2.7 2 1 0 2 2 2 2 Ninjurin DUF3450 PF11932.8 CBY07258.1 - 0.00034 20.0 9.9 0.00047 19.5 9.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 CBY07258.1 - 0.012 16.2 13.9 0.012 16.2 13.9 2.4 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Phlebovirus_NSM PF07246.11 CBY07258.1 - 0.037 13.4 13.3 0.049 13.0 12.4 1.6 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Retrotrans_gag PF03732.17 CBY07258.1 - 0.065 13.5 2.8 0.13 12.5 2.8 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein DUF4407 PF14362.6 CBY07258.1 - 0.11 11.8 6.9 0.13 11.6 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 CBY07258.1 - 0.27 11.3 19.2 1.7 8.7 19.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF5094 PF17015.5 CBY07258.1 - 0.36 10.9 14.7 0.55 10.3 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Fez1 PF06818.15 CBY07258.1 - 0.5 10.8 18.1 0.77 10.2 8.4 1.5 1 1 1 2 2 2 0 Fez1 APG6_N PF17675.1 CBY07258.1 - 0.56 10.7 22.0 3.6 8.1 22.0 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 CBY07258.1 - 0.91 10.0 16.7 1.2 9.6 15.2 1.9 2 1 0 2 2 1 0 Centromere protein H (CENP-H) FTA4 PF13093.6 CBY07258.1 - 1 9.3 12.9 1.5 8.6 12.9 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 V_ATPase_I PF01496.19 CBY07258.1 - 1.1 7.0 12.7 1.3 6.8 12.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CK1gamma_C PF12605.8 CBY07258.1 - 1.2 10.3 4.2 2.7 9.2 4.0 1.8 1 1 0 1 1 1 0 Casein kinase 1 gamma C terminal CP12 PF02672.15 CBY07258.1 - 2.3 9.0 7.9 5.2 7.9 7.4 1.9 1 1 0 1 1 1 0 CP12 domain TMPIT PF07851.13 CBY07258.1 - 2.9 7.1 11.2 3.7 6.7 11.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein USP8_interact PF08941.10 CBY07258.1 - 2.9 7.7 11.1 0.68 9.7 4.2 2.2 1 1 1 2 2 2 0 USP8 interacting GPS2_interact PF15784.5 CBY07258.1 - 7.1 7.1 15.4 6.6 7.3 6.1 3.4 2 1 1 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF4140 PF13600.6 CBY07258.1 - 7.7 7.0 12.0 8 7.0 5.6 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 CBY07258.1 - 9.5 6.1 18.6 24 4.8 0.7 3.8 2 1 2 4 4 4 0 Septum formation initiator Kazal_1 PF00050.21 CBY07259.1 - 1.6e-18 66.4 12.6 2.7e-09 36.9 1.3 3.4 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CBY07259.1 - 4.6e-18 65.1 24.5 2.2e-10 40.5 2.4 3.8 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain EGF_CA PF07645.15 CBY07260.1 - 7e-07 29.4 0.4 7e-07 29.4 0.4 2.6 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 CBY07260.1 - 0.0081 16.1 3.7 0.0081 16.1 3.7 2.8 3 0 0 3 3 3 1 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY07260.1 - 0.11 12.6 10.6 0.26 11.4 5.0 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 Zona_pellucida PF00100.23 CBY07261.1 - 2.9e-15 56.8 2.2 3.5e-15 56.5 2.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Lectin_C PF00059.21 CBY07262.1 - 2.3e-44 150.5 25.8 4.8e-18 65.9 1.5 5.2 4 1 1 5 5 5 4 Lectin C-type domain Chordopox_A33R PF05966.12 CBY07262.1 - 2.8e-05 23.5 0.9 0.0053 16.0 0.0 2.3 2 0 0 2 2 2 2 Chordopoxvirus A33R protein UL45 PF05473.12 CBY07262.1 - 0.00021 21.0 0.9 0.75 9.4 0.0 3.2 3 0 0 3 3 3 2 UL45 protein, carbohydrate-binding C-type lectin-like Trefoil PF00088.18 CBY07262.1 - 0.0048 16.8 4.0 0.0048 16.8 4.0 2.4 2 0 0 2 2 2 1 Trefoil (P-type) domain SKG6 PF08693.10 CBY07262.1 - 0.28 10.6 2.4 0.48 9.9 2.4 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NADH_dehy_S2_C PF06444.11 CBY07264.1 - 0.0049 17.4 0.2 0.012 16.1 0.2 1.8 1 0 0 1 1 1 1 NADH dehydrogenase subunit 2 C-terminus ubiquitin PF00240.23 CBY07265.1 - 1.7e-05 24.5 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 CBY07265.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Zona_pellucida PF00100.23 CBY07267.1 - 2.8e-11 43.7 0.0 3.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain ETRAMP PF09716.10 CBY07267.1 - 0.055 13.5 0.0 0.069 13.2 0.0 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Marek_A PF02124.15 CBY07267.1 - 0.25 11.1 2.3 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 Marek's disease glycoprotein A EGF_CA PF07645.15 CBY07268.1 - 2.7e-148 482.0 675.5 6.2e-10 39.1 4.5 45.0 44 2 3 47 47 47 31 Calcium-binding EGF domain EGF_3 PF12947.7 CBY07268.1 - 4.3e-121 394.8 547.2 2.6e-10 40.3 6.1 40.9 40 2 1 42 42 42 30 EGF domain cEGF PF12662.7 CBY07268.1 - 2e-50 168.3 382.3 3.3e-06 26.9 6.3 39.5 40 1 1 41 41 41 27 Complement Clr-like EGF-like TIL PF01826.17 CBY07268.1 - 1.7e-13 50.6 73.5 1.1e-07 31.9 19.5 36.5 19 7 14 35 35 35 9 Trypsin Inhibitor like cysteine rich domain EGF PF00008.27 CBY07268.1 - 7.5e-11 42.1 527.5 9.6e-06 25.8 10.8 40.8 41 3 1 42 42 42 26 EGF-like domain EGF_MSP1_1 PF12946.7 CBY07268.1 - 3.1e-09 36.7 408.4 0.00082 19.4 0.9 37.4 35 2 2 37 37 37 18 MSP1 EGF domain 1 hEGF PF12661.7 CBY07268.1 - 0.00032 21.2 23.2 0.00055 20.5 3.9 42.0 45 0 0 45 45 45 19 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY07268.1 - 0.0012 19.1 5.2 0.0012 19.1 5.2 38.9 32 6 7 39 39 39 18 Coagulation Factor Xa inhibitory site CUB PF00431.20 CBY07269.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.6 1 1 0 1 1 1 1 CUB domain PDZ PF00595.24 CBY07272.1 - 3.5e-16 59.3 0.3 6.1e-16 58.5 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY07272.1 - 5.1e-12 45.5 0.0 8.9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY07272.1 - 1.5e-08 34.8 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 CBY07272.1 - 0.00026 20.9 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain DUF3140 PF11338.8 CBY07272.1 - 0.049 14.1 0.3 0.085 13.3 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) Sulfotransfer_1 PF00685.27 CBY07273.1 - 2.2e-06 27.4 0.2 4.5e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY07273.1 - 0.052 13.9 0.0 0.17 12.3 0.0 2.1 1 1 0 1 1 1 0 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 CBY07275.1 - 6.5e-10 38.5 0.0 8e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfatase PF00884.23 CBY07276.1 - 8.7e-32 110.7 0.2 1e-31 110.5 0.2 1.0 1 0 0 1 1 1 1 Sulfatase Pkinase PF00069.25 CBY07277.1 - 1.4e-22 80.3 0.0 2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY07277.1 - 1.2e-08 34.2 0.2 2.2e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CBY07277.1 - 1.6e-08 34.1 0.0 6.6e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY07277.1 - 0.035 14.0 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fer4_16 PF13484.6 CBY07279.1 - 0.027 15.4 0.2 0.071 14.1 0.2 1.6 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 CBY07279.1 - 0.04 14.5 0.1 0.077 13.6 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 CBY07279.1 - 0.09 12.6 2.7 0.14 12.0 2.7 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain PCRF PF03462.18 CBY07280.1 - 0.079 12.8 1.0 3.2 7.6 0.1 2.6 3 0 0 3 3 3 0 PCRF domain API5 PF05918.11 CBY07280.1 - 0.34 9.7 8.3 0.57 8.9 8.3 1.5 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RPAP3_C PF13877.6 CBY07281.1 - 0.059 13.9 0.5 1.4 9.6 0.0 2.3 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 LdpA_C PF12617.8 CBY07281.1 - 0.13 11.8 0.0 0.84 9.2 0.0 1.9 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal Troponin PF00992.20 CBY07283.1 - 2.2e-05 24.8 26.7 2.4e-05 24.7 26.7 1.0 1 0 0 1 1 1 1 Troponin DARPP-32 PF05395.12 CBY07283.1 - 0.0073 16.5 8.9 0.0091 16.2 8.9 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 Corazonin PF17308.2 CBY07283.1 - 0.1 13.0 5.0 0.15 12.4 5.0 1.4 1 1 0 1 1 1 0 Pro-corazonin THAP PF05485.12 CBY07283.1 - 0.23 12.4 4.8 0.59 11.1 4.8 2.0 1 1 0 1 1 1 0 THAP domain Synaptobrevin PF00957.21 CBY07283.1 - 1 9.2 6.8 0.63 9.9 3.6 2.0 1 1 1 2 2 2 0 Synaptobrevin PGA2 PF07543.12 CBY07283.1 - 1.2 9.1 20.1 1.5 8.8 20.1 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 HSP70 PF00012.20 CBY07283.1 - 3.2 5.8 12.6 3.4 5.7 12.6 1.1 1 0 0 1 1 1 0 Hsp70 protein Sulfotransfer_2 PF03567.14 CBY07284.1 - 7.9e-19 68.5 0.1 1.1e-18 68.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY07284.1 - 0.00013 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain DUF2740 PF10872.8 CBY07284.1 - 0.1 12.5 0.6 0.77 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2740) HAP1_N PF04849.13 CBY07285.1 - 0.0013 18.0 37.6 0.0027 16.9 37.3 1.9 1 1 0 1 1 1 1 HAP1 N-terminal conserved region DUF573 PF04504.14 CBY07285.1 - 0.0014 19.3 2.4 0.0014 19.3 2.4 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF573 APG6_N PF17675.1 CBY07285.1 - 0.0078 16.8 9.9 0.0078 16.8 9.9 3.2 2 1 1 3 3 3 1 Apg6 coiled-coil region bZIP_1 PF00170.21 CBY07285.1 - 0.012 15.7 0.4 0.012 15.7 0.4 5.1 5 1 0 5 5 5 0 bZIP transcription factor YlqD PF11068.8 CBY07285.1 - 0.017 15.5 9.7 0.017 15.5 9.7 3.0 2 1 1 3 3 3 0 YlqD protein FliT PF05400.13 CBY07285.1 - 0.028 15.2 0.6 0.028 15.2 0.6 3.7 1 1 2 4 4 4 0 Flagellar protein FliT Mt_ATP-synt_D PF05873.12 CBY07285.1 - 0.11 12.3 9.0 0.063 13.1 0.7 2.7 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1043 PF06295.12 CBY07285.1 - 0.29 11.2 18.7 0.89 9.6 7.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3452 PF11934.8 CBY07285.1 - 0.46 10.0 5.8 1.8 8.1 0.5 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF3452) MbeD_MobD PF04899.12 CBY07285.1 - 2 8.6 8.8 3.1 8.0 0.2 3.6 3 1 0 3 3 3 0 MbeD/MobD like RRM_1 PF00076.22 CBY07286.1 - 5.9e-16 58.0 0.0 1e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COesterase PF00135.28 CBY07287.1 - 4.5e-64 217.2 0.0 6.1e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CBY07287.1 - 3e-05 23.6 0.1 5.4e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CBY07287.1 - 0.00015 21.7 2.2 0.0029 17.5 2.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold EF-hand_1 PF00036.32 CBY07288.1 - 9e-15 53.1 6.3 0.00042 19.7 0.0 4.4 3 1 1 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY07288.1 - 1.1e-13 49.9 1.9 0.00044 19.9 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CBY07288.1 - 3.7e-12 46.5 1.1 5.5e-05 23.5 0.6 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY07288.1 - 3e-10 39.1 4.6 0.00091 18.6 0.2 3.9 4 0 0 4 4 4 3 EF hand EF-hand_14 PF17959.1 CBY07288.1 - 0.00018 21.8 0.0 0.0016 18.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBY07288.1 - 0.00057 19.7 7.3 0.34 10.8 0.3 4.4 3 1 1 4 4 4 1 EF-hand domain pair DUF489 PF04356.12 CBY07288.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Excalibur PF05901.11 CBY07288.1 - 4.8 7.9 6.0 13 6.5 0.5 3.1 3 1 0 3 3 3 0 Excalibur calcium-binding domain NodS PF05401.11 CBY07289.1 - 0.075 12.6 0.1 0.097 12.3 0.1 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Chal_sti_synt_C PF02797.15 CBY07289.1 - 0.2 11.6 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Toxin_35 PF10530.9 CBY07289.1 - 2.9 7.9 12.9 9 6.4 1.0 2.2 1 1 1 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold UAF_Rrn10 PF05234.11 CBY07290.1 - 0.041 14.1 0.1 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 UAF complex subunit Rrn10 Pkinase PF00069.25 CBY07291.1 - 2.9e-31 108.8 0.0 1.1e-30 106.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY07291.1 - 2.4e-28 99.1 0.2 2.5e-27 95.8 0.2 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBY07291.1 - 4e-05 23.4 0.1 0.0019 17.9 0.0 2.9 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBY07291.1 - 0.0028 16.5 0.0 0.0056 15.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY07291.1 - 0.025 13.9 0.0 0.21 10.9 0.0 2.3 3 0 0 3 3 3 0 Kinase-like MFS_2 PF13347.6 CBY07291.1 - 0.043 12.4 0.0 0.066 11.8 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein ASFV_J13L PF05568.11 CBY07291.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Fn_bind PF02986.14 CBY07291.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Fibronectin binding repeat APH PF01636.23 CBY07291.1 - 0.17 11.8 0.1 1.7 8.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_6 PF13516.6 CBY07292.1 - 6.3e-19 66.4 17.7 0.02 14.9 0.0 11.6 12 1 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 CBY07292.1 - 2e-15 56.6 26.2 0.0063 16.9 0.3 8.7 6 3 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY07292.1 - 5.9e-05 23.1 20.0 67 4.6 0.1 10.6 11 1 0 11 11 11 0 Leucine Rich Repeat BRCA2 PF00634.18 CBY07292.1 - 0.061 13.0 0.3 0.16 11.6 0.3 1.8 1 0 0 1 1 1 0 BRCA2 repeat Aminotran_1_2 PF00155.21 CBY07293.1 - 1.7e-59 201.9 0.0 4.7e-57 193.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 CBY07293.1 - 0.0018 17.0 0.0 0.016 13.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-III SepSecS PF05889.13 CBY07293.1 - 0.0018 17.0 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 CBY07293.1 - 0.0031 16.1 0.2 0.014 14.0 0.1 1.8 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CBY07293.1 - 0.012 14.6 0.0 0.039 12.9 0.0 1.7 1 1 1 2 2 2 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBY07293.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CBY07293.1 - 0.051 12.9 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF759 PF05537.11 CBY07293.1 - 0.074 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Trypsin PF00089.26 CBY07294.1 - 7.7e-49 166.5 1.2 7.7e-49 166.5 1.2 1.5 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 CBY07294.1 - 0.00012 22.4 0.1 0.00037 20.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Mucin PF01456.17 CBY07294.1 - 3.2 7.7 32.0 5.3 7.0 32.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Kelch_6 PF13964.6 CBY07297.1 - 0.05 13.9 0.8 3.5 8.0 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY07297.1 - 0.068 13.2 0.1 0.068 13.2 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 CBY07297.1 - 0.095 12.7 1.2 16 5.7 0.1 3.2 3 0 0 3 3 3 0 Kelch motif DsrC PF04358.13 CBY07297.1 - 0.31 11.6 1.8 1.8 9.1 0.1 2.8 3 0 0 3 3 3 0 DsrC like protein EF-hand_1 PF00036.32 CBY07298.1 - 1.1e-08 34.0 8.1 5.7e-05 22.4 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY07298.1 - 2.5e-08 33.2 6.0 0.0003 20.5 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY07298.1 - 1.5e-06 28.6 7.6 0.003 18.0 1.9 3.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY07298.1 - 0.00084 19.1 6.9 0.21 11.5 0.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair DUF5601 PF18151.1 CBY07298.1 - 0.018 15.3 7.7 6.3 7.2 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) EF-hand_5 PF13202.6 CBY07298.1 - 0.026 14.0 6.4 0.16 11.5 0.0 3.1 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.9 CBY07298.1 - 0.037 14.4 2.2 0.28 11.5 0.6 3.0 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3510 PF12022.8 CBY07298.1 - 0.13 12.6 1.9 8.6 6.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Scramblase PF03803.15 CBY07299.1 - 7.8e-32 110.4 0.5 1.2e-31 109.7 0.5 1.3 1 1 0 1 1 1 1 Scramblase AtuA PF07287.11 CBY07300.1 - 1.2e-108 363.0 0.3 1.7e-108 362.5 0.3 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DcpS_C PF11969.8 CBY07301.1 - 6.4e-26 91.1 0.3 1.2e-25 90.2 0.3 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 CBY07301.1 - 2.2e-10 41.3 0.0 5.2e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal zf-C2HE PF16278.5 CBY07301.1 - 0.073 13.5 0.2 0.23 11.9 0.2 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger CKS PF01111.19 CBY07302.1 - 8.7e-35 118.8 0.7 9.5e-35 118.7 0.7 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Reprolysin PF01421.19 CBY07303.1 - 4.7e-13 49.5 0.0 4.5e-12 46.3 0.0 2.5 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 CBY07303.1 - 1.3e-10 41.8 0.1 2.4e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY07303.1 - 5.4e-08 33.4 0.2 1e-07 32.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CBY07303.1 - 1.6e-07 32.0 30.4 1.6e-07 32.0 30.4 3.6 2 1 0 2 2 1 1 Disintegrin Reprolysin_2 PF13574.6 CBY07303.1 - 1.7e-05 24.8 0.1 3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY07303.1 - 3.5e-05 23.5 0.3 5.8e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Sulfotransfer_3 PF13469.6 CBY07303.1 - 5.7e-05 23.6 0.0 0.33 11.3 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family Peptidase_M57 PF12388.8 CBY07303.1 - 0.0029 17.2 0.9 0.0056 16.3 0.2 1.8 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 CBY07303.1 - 0.012 15.5 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Matrixin PEMT PF04191.13 CBY07303.1 - 0.015 15.7 2.3 0.015 15.7 2.3 2.5 3 0 0 3 3 2 0 Phospholipid methyltransferase DUF3810 PF12725.7 CBY07303.1 - 0.016 14.6 0.1 0.016 14.6 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) Peptidase_M54 PF07998.11 CBY07303.1 - 0.067 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M54 DUF4373 PF14297.6 CBY07303.1 - 0.11 13.3 0.2 0.5 11.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) ICMT PF04140.14 CBY07303.1 - 4.3 7.8 5.6 0.82 10.1 0.3 2.4 3 0 0 3 3 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family COesterase PF00135.28 CBY07304.1 - 2.4e-41 142.2 0.0 2.8e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY07304.1 - 3.8e-09 36.7 0.1 5.5e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PilJ_C PF18223.1 CBY07304.1 - 0.054 14.0 0.0 0.092 13.3 0.0 1.3 1 0 0 1 1 1 0 Pili PilJ C-terminal domain Phospholip_A2_1 PF00068.19 CBY07305.1 - 1.1e-09 38.8 14.4 2.7e-09 37.5 14.4 1.6 1 1 0 1 1 1 1 Phospholipase A2 MMR_HSR1_C PF08438.10 CBY07305.1 - 0.0059 17.2 0.0 0.024 15.2 0.0 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal Occludin_ELL PF07303.13 CBY07306.1 - 0.0025 18.5 15.4 0.051 14.3 0.3 4.1 2 1 0 3 3 3 2 Occludin homology domain Ntox1 PF15500.6 CBY07306.1 - 0.088 13.2 0.3 14 6.1 0.1 2.7 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 Sbi-IV PF11621.8 CBY07306.1 - 0.27 11.6 5.5 5.1 7.5 0.3 3.7 3 1 0 3 3 3 0 C3 binding domain 4 of IgG-bind protein SBI PKcGMP_CC PF16808.5 CBY07306.1 - 2.2 8.2 10.0 1.3 8.9 1.0 3.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CUB PF00431.20 CBY07307.1 - 1.9e-12 47.5 0.0 3.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 CUB domain Mtc PF03820.17 CBY07308.1 - 1.5e-94 316.6 0.0 1.7e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Trefoil PF00088.18 CBY07311.1 - 0.013 15.4 12.2 0.022 14.7 3.3 5.3 5 0 0 5 5 5 0 Trefoil (P-type) domain DUF4541 PF15074.6 CBY07313.1 - 0.00092 19.8 0.1 0.0029 18.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Mt_ATP-synt_B PF05405.14 CBY07313.1 - 0.13 11.9 2.7 0.2 11.3 2.7 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FAM183 PF14886.6 CBY07313.1 - 0.33 11.7 3.9 1.7 9.4 3.9 2.3 1 1 0 1 1 1 0 FAM183A and FAM183B related RRM_1 PF00076.22 CBY07314.1 - 3.8e-10 39.4 0.0 4.5e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CBY07314.1 - 0.02 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBY07314.1 - 0.077 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 CBY07315.1 - 1.4e-09 37.6 0.1 3.1e-09 36.5 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CBY07315.1 - 0.022 14.7 0.0 0.067 13.1 0.0 1.8 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY07315.1 - 0.035 14.2 0.0 0.074 13.1 0.0 1.5 1 1 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 CBY07315.1 - 0.23 11.4 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif GPI2 PF06432.11 CBY07316.1 - 2.5e-16 59.9 21.1 3.8e-16 59.4 21.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Abhydrolase_1 PF00561.20 CBY07317.1 - 1.9e-18 67.0 0.1 3.1e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CBY07317.1 - 1.4e-11 43.8 0.0 3.5e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CBY07317.1 - 2.8e-06 26.8 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 UDG PF03167.19 CBY07317.1 - 0.11 12.4 0.0 27 4.7 0.0 3.0 3 0 0 3 3 3 0 Uracil DNA glycosylase superfamily Connexin PF00029.19 CBY07319.1 - 1.3e-58 198.6 10.9 5.8e-38 131.0 0.3 2.5 2 1 1 3 3 3 2 Connexin Glyco_transf_7N PF13733.6 CBY07319.1 - 6.4e-46 155.3 0.0 1.7e-45 154.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY07319.1 - 1.3e-17 63.2 0.5 2.7e-17 62.2 0.5 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CUB PF00431.20 CBY07320.1 - 2e-06 28.1 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 CUB domain Gly_transf_sug PF04488.15 CBY07322.1 - 2.3e-06 28.2 0.0 5.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CBY07322.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gb3_synth PF04572.12 CBY07322.1 - 0.024 14.8 1.0 0.024 14.8 1.0 1.8 2 1 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region ABC_membrane PF00664.23 CBY07323.1 - 9.2e-10 38.6 0.2 1.1e-09 38.4 0.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 CBY07324.1 - 3.8e-94 315.4 19.5 7e-53 180.0 11.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY07324.1 - 1.5e-73 245.7 1.1 1.4e-36 126.0 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 CBY07324.1 - 3.4e-17 62.6 0.0 1.1e-07 31.5 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CBY07324.1 - 1.1e-09 38.6 0.1 0.0015 18.8 0.0 3.3 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CBY07324.1 - 8.6e-09 35.5 0.1 0.0054 16.7 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 CBY07324.1 - 8.4e-08 32.3 0.5 0.0043 16.8 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CBY07324.1 - 4e-07 29.2 0.2 0.015 14.1 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 CBY07324.1 - 6e-06 26.7 0.7 0.038 14.4 0.1 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CBY07324.1 - 6.1e-06 26.7 1.3 0.82 10.1 0.2 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CBY07324.1 - 2.1e-05 24.2 0.9 0.31 10.8 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_30 PF13604.6 CBY07324.1 - 5.1e-05 23.1 1.3 0.3 10.8 0.2 3.6 2 2 0 2 2 2 2 AAA domain Rad17 PF03215.15 CBY07324.1 - 9e-05 22.5 0.7 0.18 11.7 0.0 2.8 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_7 PF12775.7 CBY07324.1 - 0.00037 20.0 0.1 0.23 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 CBY07324.1 - 0.00046 20.4 4.4 1.4 9.2 0.4 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 CBY07324.1 - 0.001 18.3 0.1 0.45 9.6 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.14 CBY07324.1 - 0.0027 17.7 0.0 2.3 8.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBY07324.1 - 0.0037 17.6 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase PRK PF00485.18 CBY07324.1 - 0.0053 16.5 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 CBY07324.1 - 0.0054 16.0 2.3 0.13 11.6 0.0 3.1 4 0 0 4 4 4 1 Zeta toxin AAA_10 PF12846.7 CBY07324.1 - 0.0058 15.6 0.1 2.3 7.1 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain ATP-synt_ab PF00006.25 CBY07324.1 - 0.016 14.9 1.4 6.1 6.4 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 CBY07324.1 - 0.02 14.5 0.1 8.4 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CBY07324.1 - 0.02 14.7 0.4 8.6 6.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 CBY07324.1 - 0.023 13.9 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CBY07324.1 - 0.052 13.3 2.7 5.3 6.7 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_33 PF13671.6 CBY07324.1 - 0.066 13.4 0.0 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBY07324.1 - 0.12 11.5 0.4 12 5.0 0.1 3.2 3 0 0 3 3 3 0 NB-ARC domain PDR_CDR PF06422.12 CBY07324.1 - 0.56 10.1 2.3 0.6 10.0 0.3 2.1 2 0 0 2 2 1 0 CDR ABC transporter AAA_23 PF13476.6 CBY07324.1 - 6.8 7.1 11.2 1.1 9.7 0.1 3.1 3 0 0 3 3 2 0 AAA domain Ank_4 PF13637.6 CBY07325.1 - 7.4e-06 26.4 0.0 1.2e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY07325.1 - 2.5e-05 24.8 0.0 3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY07325.1 - 4.2e-05 23.6 0.0 0.00015 21.9 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CBY07325.1 - 8.7e-05 22.8 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 CBY07325.1 - 0.0004 20.6 0.0 0.00067 19.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RRM_5 PF13893.6 CBY07325.1 - 0.087 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phospholip_A2_1 PF00068.19 CBY07326.1 - 8.6e-10 39.1 6.1 8.6e-10 39.1 6.1 2.2 2 0 0 2 2 2 1 Phospholipase A2 CH PF00307.31 CBY07327.1 - 1e-73 244.5 3.8 3e-19 69.2 0.1 5.1 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBY07327.1 - 4.6e-05 23.2 0.2 0.026 14.3 0.1 3.2 3 0 0 3 3 3 2 CAMSAP CH domain An_peroxidase PF03098.15 CBY07328.1 - 7.5e-101 338.3 0.0 8.9e-101 338.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase PT PF04886.12 CBY07328.1 - 1 9.0 45.9 0.24 11.0 28.7 2.6 1 1 1 2 2 2 0 PT repeat SSP160 PF06933.11 CBY07329.1 - 0.16 10.2 17.4 0.24 9.5 17.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AJAP1_PANP_C PF15298.6 CBY07329.1 - 0.27 11.5 12.5 0.2 11.9 10.7 1.7 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Dicty_REP PF05086.12 CBY07329.1 - 0.73 7.7 8.2 0.93 7.4 8.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 CBY07329.1 - 1.4 6.9 9.9 1.9 6.5 9.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RhoGEF PF00621.20 CBY07331.1 - 8.8e-29 101.0 7.5 8.8e-29 101.0 7.5 1.9 3 0 0 3 3 3 1 RhoGEF domain DUF3388 PF11868.8 CBY07331.1 - 0.014 14.7 0.5 0.029 13.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) Septin PF00735.18 CBY07332.1 - 2.8e-37 128.6 10.6 2.7e-20 72.8 0.2 3.4 3 1 1 4 4 4 3 Septin HigB-like_toxin PF05015.13 CBY07332.1 - 0.28 11.6 4.2 0.28 11.6 2.3 2.0 2 0 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB Exonuc_VII_L PF02601.15 CBY07332.1 - 0.69 9.4 7.0 0.57 9.7 5.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Trypsin PF00089.26 CBY07333.1 - 1e-43 149.7 0.0 1.2e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin Inositol_P PF00459.25 CBY07334.1 - 4.9e-37 127.9 0.0 5.8e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family PspB PF06667.12 CBY07334.1 - 0.0066 16.5 0.3 0.015 15.3 0.3 1.6 1 0 0 1 1 1 1 Phage shock protein B PhoPQ_related PF10142.9 CBY07335.1 - 1.2e-57 195.3 3.4 1e-28 100.1 0.3 2.0 2 0 0 2 2 2 2 PhoPQ-activated pathogenicity-related protein Trypsin PF00089.26 CBY07336.1 - 1.3e-58 198.4 0.7 2.4e-58 197.6 0.7 1.5 1 0 0 1 1 1 1 Trypsin EGF_CA PF07645.15 CBY07336.1 - 2.2e-14 53.4 29.9 3.4e-10 40.0 12.1 7.8 5 2 3 8 8 8 2 Calcium-binding EGF domain EGF PF00008.27 CBY07336.1 - 5.9e-12 45.7 88.8 3.5e-06 27.2 10.3 7.4 7 0 0 7 7 7 5 EGF-like domain EGF_3 PF12947.7 CBY07336.1 - 4.7e-07 29.9 25.0 5.7e-05 23.2 6.9 7.4 6 0 0 6 6 6 2 EGF domain cEGF PF12662.7 CBY07336.1 - 0.0005 19.9 12.5 0.0013 18.7 5.7 6.4 6 1 0 6 6 6 2 Complement Clr-like EGF-like EGF_2 PF07974.13 CBY07336.1 - 0.0012 19.2 10.6 0.0012 19.2 10.6 7.2 6 0 0 6 6 6 2 EGF-like domain FXa_inhibition PF14670.6 CBY07336.1 - 0.0043 17.3 67.7 0.03 14.6 10.5 7.0 4 2 2 6 6 6 3 Coagulation Factor Xa inhibitory site DUF1986 PF09342.11 CBY07336.1 - 0.0048 17.3 0.0 0.0097 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) hEGF PF12661.7 CBY07336.1 - 0.0049 17.5 6.8 0.0049 17.5 6.8 8.3 9 0 0 9 9 9 5 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 CBY07336.1 - 7.9 6.9 42.4 0.067 13.5 3.6 5.8 4 0 0 4 4 4 0 Pvs28 EGF domain LepB_GAP_N PF18172.1 CBY07337.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 LepB GAP domain N-terminal subdomain AF-4 PF05110.13 CBY07338.1 - 0.92 7.5 28.4 1 7.4 28.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SRP-alpha_N PF04086.13 CBY07338.1 - 9.3 6.1 33.3 12 5.7 33.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Gal-3-0_sulfotr PF06990.11 CBY07339.1 - 1.3e-31 110.0 1.8 2.2e-16 59.8 0.0 2.0 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Med30 PF11315.8 CBY07339.1 - 0.56 10.4 3.3 13 6.0 0.1 2.5 1 1 0 2 2 2 0 Mediator complex subunit 30 Abhydrolase_3 PF07859.13 CBY07340.1 - 1.8e-43 148.9 0.0 1.2e-34 120.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 CBY07340.1 - 5.4e-07 28.8 0.0 1.8e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CBY07340.1 - 0.002 17.7 0.0 0.0045 16.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CBY07340.1 - 0.021 14.4 0.1 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 CBY07340.1 - 0.031 13.2 0.0 0.086 11.7 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase GlpM PF06942.12 CBY07340.1 - 0.052 14.0 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 GlpM protein Abhydrolase_2 PF02230.16 CBY07340.1 - 0.062 13.1 0.0 16 5.2 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 CBY07340.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.12 CBY07340.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) rve PF00665.26 CBY07343.1 - 1.8e-05 24.9 0.0 3.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Neur_chan_memb PF02932.16 CBY07343.1 - 0.64 10.0 3.0 2 8.4 3.0 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SF-assemblin PF06705.11 CBY07344.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF4687 PF15747.5 CBY07346.1 - 0.08 13.4 1.9 0.18 12.3 1.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) FAM199X PF15814.5 CBY07346.1 - 9.3 5.2 16.7 19 4.2 0.0 2.1 2 0 0 2 2 2 0 Protein family FAM199X RT_RNaseH PF17917.1 CBY07347.1 - 2.2e-29 101.8 0.0 5.2e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY07347.1 - 5.7e-27 93.7 0.0 1.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY07347.1 - 2.6e-17 63.1 0.1 5e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY07347.1 - 2.6e-17 63.1 0.0 7.1e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY07347.1 - 7.9e-08 32.3 0.3 2.9e-07 30.5 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_thumb PF06817.14 CBY07347.1 - 0.13 12.1 0.3 0.94 9.4 0.3 2.3 1 1 0 1 1 1 0 Reverse transcriptase thumb domain RT_RNaseH PF17917.1 CBY07348.1 - 2.2e-25 89.0 0.0 4.1e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY07348.1 - 1.3e-22 79.7 0.0 3.3e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY07348.1 - 6.1e-05 23.1 0.5 0.00016 21.7 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CBY07348.1 - 0.018 15.2 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger ATP13 PF12921.7 CBY07348.1 - 0.043 13.7 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase expression RT_RNaseH_2 PF17919.1 CBY07349.1 - 2.4e-23 82.0 0.0 8e-23 80.4 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY07349.1 - 6e-15 55.4 0.6 1.1e-14 54.5 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CBY07349.1 - 9.1e-14 51.6 0.0 1.8e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_pol_viral_C PF00336.18 CBY07349.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Lactamase_B_6 PF16661.5 CBY07349.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain zf-C2H2 PF00096.26 CBY07350.1 - 5.1e-13 48.7 16.2 0.00028 21.2 4.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY07350.1 - 2.7e-11 43.5 5.2 0.00026 21.2 0.1 3.6 2 1 1 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CBY07350.1 - 9.9e-11 41.5 12.3 0.0018 18.9 2.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY07350.1 - 5.9e-08 32.8 9.5 0.013 15.9 0.3 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBY07350.1 - 0.00016 21.9 23.0 0.069 13.6 0.2 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY07350.1 - 0.0002 21.3 14.7 0.071 13.1 2.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY07350.1 - 0.0098 15.6 4.7 0.95 9.3 0.4 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-BED PF02892.15 CBY07350.1 - 0.04 14.0 10.5 4.9 7.3 0.2 3.0 1 1 1 2 2 2 0 BED zinc finger ADK_lid PF05191.14 CBY07350.1 - 0.07 13.1 4.9 3.6 7.6 0.2 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 CBY07350.1 - 0.2 12.0 8.8 6.4 7.2 8.9 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 CBY07350.1 - 4.2 7.6 9.1 29 4.9 9.1 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-C2HC_2 PF13913.6 CBY07350.1 - 6.3 6.8 11.2 3.7 7.5 0.2 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Tcell_CD4_C PF12104.8 CBY07351.1 - 0.12 12.4 1.7 0.27 11.2 1.7 1.6 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region Trnau1ap PF17654.1 CBY07352.1 - 1.6 9.7 8.0 2.7 8.9 2.6 2.8 2 0 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins FCH PF00611.23 CBY07354.1 - 0.051 13.9 0.3 0.14 12.5 0.3 1.8 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain SRP-alpha_N PF04086.13 CBY07354.1 - 0.19 11.6 12.4 0.35 10.7 12.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal rve PF00665.26 CBY07355.1 - 1.1e-13 51.5 0.0 1.5e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CBY07356.1 - 7.6e-24 83.7 0.0 1.6e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY07356.1 - 1.4e-15 57.4 0.0 3.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY07356.1 - 1.9e-13 50.5 0.2 4.3e-13 49.3 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY07356.1 - 9.5e-09 35.2 0.1 1.9e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DNA_pol_viral_C PF00336.18 CBY07356.1 - 0.0068 15.8 0.0 0.022 14.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase (viral) C-terminal domain rve PF00665.26 CBY07356.1 - 0.025 14.8 0.0 0.076 13.2 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 CBY07357.1 - 4.2e-17 62.4 0.1 7e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CBY07357.1 - 8.6e-15 54.6 0.0 1.6e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY07357.1 - 3.7e-07 30.4 0.0 7.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SP_C-Propep PF08999.10 CBY07357.1 - 0.42 10.4 4.3 0.87 9.4 4.3 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide PRA1 PF03208.19 CBY07357.1 - 0.57 9.8 3.4 0.86 9.2 3.4 1.3 1 0 0 1 1 1 0 PRA1 family protein FAM220 PF15487.6 CBY07358.1 - 0.01 15.5 1.3 0.01 15.5 1.3 2.5 2 0 0 2 2 2 0 FAM220 family Uteroglobin PF01099.17 CBY07358.1 - 0.077 13.3 0.1 0.29 11.5 0.1 1.9 1 0 0 1 1 1 0 Uteroglobin family DNA_primase_lrg PF04104.14 CBY07360.1 - 0.025 14.0 0.1 0.031 13.7 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit UPF0561 PF10573.9 CBY07361.1 - 0.15 12.1 0.4 0.28 11.3 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Phospholip_A2_1 PF00068.19 CBY07362.1 - 0.0065 16.9 0.6 0.0099 16.3 0.6 1.2 1 0 0 1 1 1 1 Phospholipase A2 Pox_A32 PF04665.12 CBY07363.1 - 0.00064 19.2 1.3 0.039 13.4 0.0 2.2 2 0 0 2 2 2 2 Poxvirus A32 protein ATPase PF06745.13 CBY07363.1 - 0.01 15.2 0.2 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 CBY07363.1 - 0.031 13.6 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 CBY07363.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CBY07363.1 - 0.034 13.9 0.1 0.072 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CBY07363.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CBY07363.1 - 0.081 13.1 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBY07363.1 - 0.1 12.9 0.0 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBY07363.1 - 0.12 11.5 0.0 0.32 10.2 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain RT_RNaseH_2 PF17919.1 CBY07364.1 - 1e-27 96.1 0.0 1.9e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY07364.1 - 1.6e-22 79.7 0.0 3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY07364.1 - 1.4e-05 24.7 0.4 2.7e-05 23.8 0.2 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 CBY07364.1 - 0.0018 17.7 0.0 0.0063 15.9 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Succ_DH_flav_C PF02910.20 CBY07371.1 - 0.026 14.5 0.0 6.4 6.8 0.0 2.7 1 1 1 2 2 2 0 Fumarate reductase flavoprotein C-term gag-asp_proteas PF13975.6 CBY07375.1 - 0.0002 21.8 0.2 0.00068 20.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CBY07375.1 - 0.0015 19.1 0.0 0.011 16.4 0.0 2.3 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CBY07375.1 - 0.026 14.8 0.0 0.069 13.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2972 PF11186.8 CBY07375.1 - 1 9.2 9.6 0.071 13.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) RT_RNaseH_2 PF17919.1 CBY07376.1 - 8.3e-28 96.4 0.0 7.1e-26 90.2 0.0 2.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY07376.1 - 4.7e-22 78.2 0.0 2.4e-21 76.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY07376.1 - 3.4e-18 66.0 0.0 7.9e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CBY07376.1 - 0.0001 22.8 0.0 0.00028 21.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CBY07376.1 - 0.011 16.3 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Herpes_ORF11 PF04797.13 CBY07376.1 - 0.02 13.7 0.0 0.95 8.2 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus dUTPase protein Autoind_bind PF03472.15 CBY07376.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain RNB PF00773.19 CBY07377.1 - 0.0081 15.5 0.4 0.01 15.2 0.4 1.1 1 0 0 1 1 1 1 RNB domain Cytochrom_C PF00034.21 CBY07378.1 - 1.3 10.2 3.7 14 6.9 0.0 4.0 2 1 1 3 3 3 0 Cytochrome c Goodbye PF17109.5 CBY07379.1 - 0.38 11.2 4.3 0.42 11.1 0.2 2.4 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain DUF5024 PF16427.5 CBY07379.1 - 1.2 9.5 4.2 1.7 9.0 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5024) Phage_integrase PF00589.22 CBY07380.1 - 5.7e-05 23.0 1.1 9.4e-05 22.3 0.1 2.0 2 1 0 2 2 2 1 Phage integrase family Dimer_Tnp_hAT PF05699.14 CBY07381.1 - 0.0071 16.1 0.0 0.0089 15.8 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Dimer_Tnp_hAT PF05699.14 CBY07382.1 - 3.1e-05 23.7 0.1 3.2e-05 23.6 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HIM1 PF08732.10 CBY07382.1 - 0.024 14.2 0.0 0.024 14.1 0.0 1.0 1 0 0 1 1 1 0 HIM1 Phage_integrase PF00589.22 CBY07383.1 - 1.9e-09 37.6 0.0 3.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family SRP-alpha_N PF04086.13 CBY07383.1 - 1.8 8.4 17.8 3.2 7.6 17.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RVT_1 PF00078.27 CBY07384.1 - 8.7e-12 45.0 0.0 1.7e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CBY07384.1 - 0.063 13.3 0.2 0.15 12.0 0.2 1.7 1 0 0 1 1 1 0 Pao retrotransposon peptidase ADAM_CR_2 PF17771.1 CBY07386.1 - 0.035 14.6 2.2 0.043 14.3 0.6 1.8 2 0 0 2 2 2 0 ADAM cysteine-rich domain NAD_binding_10 PF13460.6 CBY07390.1 - 1.1e-35 123.2 0.0 1.3e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CBY07390.1 - 2.1e-08 33.9 0.0 3.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CBY07390.1 - 1.5e-07 31.2 0.0 4e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 CBY07390.1 - 4.1e-05 23.8 0.0 8.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 CBY07390.1 - 0.0002 21.8 0.0 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 CBY07390.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CBY07390.1 - 0.088 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 CBY07390.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Kelch_6 PF13964.6 CBY07391.1 - 0.068 13.5 5.1 9.9 6.6 0.0 4.4 4 1 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 CBY07391.1 - 0.12 12.4 6.8 0.2 11.7 0.0 3.8 5 0 0 5 5 5 0 Kelch motif Glyco_transf_7N PF13733.6 CBY07396.1 - 1.1e-52 177.3 0.5 1.8e-52 176.5 0.5 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY07396.1 - 2.8e-20 71.7 0.0 7e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Sulfatase PF00884.23 CBY07397.1 - 1.2e-45 156.3 0.2 1.4e-36 126.5 0.3 2.2 1 1 1 2 2 2 2 Sulfatase CH PF00307.31 CBY07398.1 - 1.3e-16 60.7 0.0 2.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 CBY07398.1 - 6.3e-13 48.1 3.5 6.3e-13 48.1 3.5 1.9 2 0 0 2 2 2 1 Calponin family repeat CDC24 PF06395.11 CBY07398.1 - 0.0094 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 CBY07398.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain EGF_2 PF07974.13 CBY07399.1 - 7.1e-10 39.1 42.5 0.0025 18.1 5.6 4.0 3 1 1 4 4 4 3 EGF-like domain EGF PF00008.27 CBY07399.1 - 7.3e-10 39.0 44.3 1.9e-07 31.2 6.5 4.9 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 CBY07399.1 - 0.00031 21.3 3.5 0.00031 21.3 3.5 5.5 6 0 0 6 6 6 3 Human growth factor-like EGF Chlam_PMP PF02415.17 CBY07400.1 - 0.056 14.0 0.0 0.23 12.0 0.0 2.1 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Peptidase_M16_C PF05193.21 CBY07401.1 - 1.5e-07 31.6 0.0 1.6e-06 28.3 0.0 2.2 2 1 0 2 2 2 1 Peptidase M16 inactive domain zf-CCCH PF00642.24 CBY07403.1 - 1.4e-17 63.2 11.9 4.2e-10 39.3 2.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBY07403.1 - 7.6e-08 32.0 9.9 4.5e-05 23.1 2.1 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY07403.1 - 2.1e-07 30.8 13.4 3e-05 23.9 4.0 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CBY07403.1 - 0.032 14.9 8.1 0.15 12.8 0.9 2.3 1 1 1 2 2 2 0 Torus domain oligo_HPY PF08352.12 CBY07403.1 - 0.6 10.7 3.1 21 5.7 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH_2 PF14608.6 CBY07403.1 - 0.69 10.5 10.9 4 8.1 1.0 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger LRR_5 PF13306.6 CBY07404.1 - 1.9e-08 34.3 2.3 3.2e-08 33.6 0.2 2.3 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 CBY07404.1 - 1.8e-05 24.4 0.1 0.0013 18.4 0.0 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRRNT PF01462.18 CBY07404.1 - 0.024 14.3 2.4 0.024 14.3 2.4 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain adh_short PF00106.25 CBY07405.1 - 7.4e-45 152.8 1.6 9.4e-45 152.5 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY07405.1 - 3.7e-26 92.1 0.3 4.9e-26 91.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY07405.1 - 1.5e-11 44.5 0.5 2.4e-11 43.9 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY07405.1 - 0.0009 18.8 1.2 0.0045 16.5 1.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBY07405.1 - 0.0013 18.2 0.6 0.074 12.4 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CBY07405.1 - 0.0015 17.7 0.3 0.0024 17.0 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 CBY07405.1 - 0.0027 17.6 0.3 0.0042 17.0 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CBY07405.1 - 0.015 14.9 0.5 0.041 13.5 0.4 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA OrfB_Zn_ribbon PF07282.11 CBY07405.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain NAD_binding_10 PF13460.6 CBY07405.1 - 0.051 13.5 1.7 0.078 12.9 1.7 1.4 1 1 0 1 1 1 0 NAD(P)H-binding PGBA_N PF15436.6 CBY07405.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal SLX9 PF15341.6 CBY07406.1 - 1.4e-05 25.5 13.6 1.4e-05 25.5 13.6 2.2 2 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 NPV_P10 PF05531.12 CBY07406.1 - 0.67 10.4 3.6 0.71 10.4 1.9 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CHDCT2 PF08074.11 CBY07406.1 - 0.79 9.9 6.8 0.38 10.9 3.3 1.9 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Auxin_canalis PF05703.11 CBY07406.1 - 2.6 7.9 9.5 8.7 6.2 9.6 1.8 1 1 0 1 1 1 0 Auxin canalisation DASH_Spc19 PF08287.11 CBY07406.1 - 8.7 6.2 18.9 1.4 8.8 7.8 2.3 2 0 0 2 2 2 0 Spc19 Clat_adaptor_s PF01217.20 CBY07407.1 - 6e-52 175.3 2.1 7.9e-52 175.0 2.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LNS2 PF08235.13 CBY07408.1 - 3.5e-89 298.2 0.3 4.7e-89 297.7 0.3 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CBY07408.1 - 6e-20 71.1 0.0 1.8e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CBY07408.1 - 3.4e-16 59.2 0.0 1.3e-15 57.3 0.0 2.0 1 1 1 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF3810 PF12725.7 CBY07409.1 - 0.058 12.7 0.1 0.073 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ATG27 PF09451.10 CBY07409.1 - 0.1 12.5 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Serpin PF00079.20 CBY07410.1 - 2.9e-53 181.5 3.0 3.3e-53 181.3 3.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) ApoC-I PF04691.12 CBY07411.1 - 0.059 13.3 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Scm3 PF10384.9 CBY07412.1 - 0.0013 18.4 0.2 0.36 10.6 0.0 2.9 2 0 0 2 2 2 2 Centromere protein Scm3 PBP_dimer PF03717.15 CBY07414.1 - 0.13 12.6 0.1 2.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain Choline_kinase PF01633.20 CBY07417.1 - 2.9e-52 177.3 0.1 5.5e-52 176.4 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY07417.1 - 7.9e-10 39.1 0.0 1.7e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY07417.1 - 6.5e-05 22.4 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Sulfotransfer_1 PF00685.27 CBY07419.1 - 1.3e-12 47.8 0.1 2.2e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY07419.1 - 0.001 19.5 0.1 0.089 13.2 0.1 2.9 1 1 0 1 1 1 1 Sulfotransferase family PNPase PF03726.14 CBY07421.1 - 0.16 12.5 3.8 0.5 10.9 0.3 2.3 1 1 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain H-kinase_dim PF02895.14 CBY07421.1 - 0.18 12.2 1.9 0.84 10.1 0.1 2.4 2 1 1 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF3525 PF12039.8 CBY07423.1 - 0.081 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) HSP70 PF00012.20 CBY07424.1 - 1.6e-114 383.3 5.9 1.9e-114 383.0 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBY07424.1 - 1.8e-10 40.2 2.1 4e-08 32.5 1.1 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CBY07424.1 - 4.4e-05 23.8 0.4 0.23 11.9 0.1 3.1 2 1 0 2 2 2 2 Cell division protein FtsA DDR PF08841.10 CBY07424.1 - 0.0011 18.0 0.1 0.02 13.9 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.11 CBY07424.1 - 0.0094 15.2 0.1 0.047 12.9 0.0 2.0 1 1 0 2 2 2 1 StbA protein AnmK PF03702.14 CBY07424.1 - 0.026 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase SpoIIAA-like PF11964.8 CBY07424.1 - 0.061 14.4 0.0 0.23 12.5 0.0 1.9 1 0 0 1 1 1 0 SpoIIAA-like BcrAD_BadFG PF01869.20 CBY07424.1 - 0.07 12.6 0.0 0.8 9.1 0.0 2.3 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 CBY07424.1 - 0.14 11.3 0.6 2.7 7.2 0.1 2.7 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase Bax1-I PF01027.20 CBY07425.1 - 0.033 14.0 26.2 0.47 10.2 26.2 2.1 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Pterin_4a PF01329.19 CBY07426.1 - 2.4e-23 82.1 0.1 3e-23 81.8 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase COesterase PF00135.28 CBY07427.1 - 6.4e-112 375.0 0.6 6.9e-62 210.0 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY07427.1 - 5.4e-15 55.8 0.6 8.3e-08 32.3 0.1 3.6 2 2 0 2 2 2 2 alpha/beta hydrolase fold EGF_3 PF12947.7 CBY07427.1 - 1.9e-08 34.4 8.2 1.9e-08 34.4 8.2 4.0 3 0 0 3 3 3 1 EGF domain EGF PF00008.27 CBY07427.1 - 0.00052 20.3 8.9 0.00052 20.3 8.9 3.5 3 0 0 3 3 3 2 EGF-like domain cEGF PF12662.7 CBY07427.1 - 0.0067 16.3 2.1 0.0067 16.3 2.1 3.8 4 0 0 4 4 4 1 Complement Clr-like EGF-like Say1_Mug180 PF10340.9 CBY07427.1 - 0.073 11.9 0.1 0.66 8.8 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase Plasmod_Pvs28 PF06247.11 CBY07427.1 - 0.084 13.2 23.9 0.05 13.9 8.3 2.9 2 0 0 2 2 2 0 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 CBY07427.1 - 0.089 12.9 32.8 0.064 13.3 8.2 4.1 4 0 0 4 4 4 0 MSP1 EGF domain 1 hEGF PF12661.7 CBY07427.1 - 0.52 11.0 16.0 0.7 10.6 3.6 3.6 2 0 0 2 2 2 0 Human growth factor-like EGF Phospholip_A2_1 PF00068.19 CBY07428.1 - 1.3e-14 54.7 9.1 1.3e-14 54.7 9.1 2.3 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY07429.1 - 1.4e-20 73.8 6.0 3.2e-20 72.7 6.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 Tudor-knot PF11717.8 CBY07430.1 - 3.7e-11 42.7 0.4 8.6e-11 41.6 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.13 CBY07430.1 - 1.5e-09 37.4 1.5 7.1e-08 32.0 0.9 2.4 1 1 0 1 1 1 1 MRG Chromo PF00385.24 CBY07430.1 - 0.03 14.2 2.9 0.03 14.2 2.9 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain MRG PF05712.13 CBY07432.1 - 1.9e-07 30.6 0.4 0.0078 15.5 0.1 2.1 1 1 1 2 2 2 2 MRG bZIP_2 PF07716.15 CBY07432.1 - 6.4e-05 23.0 3.9 6.4e-05 23.0 3.9 1.9 2 0 0 2 2 2 1 Basic region leucine zipper DUF5104 PF17117.5 CBY07432.1 - 0.042 14.3 0.3 4.1 7.9 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5104) DGC PF08859.11 CBY07432.1 - 0.13 12.4 0.1 10 6.3 0.0 2.3 2 0 0 2 2 2 0 DGC domain 4HB_MCP_1 PF12729.7 CBY07432.1 - 0.34 10.5 1.2 18 4.8 0.1 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Tudor-knot PF11717.8 CBY07434.1 - 4e-11 42.6 0.8 9.2e-11 41.5 0.8 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.13 CBY07434.1 - 1.6e-09 37.4 1.7 6.4e-08 32.1 0.7 2.4 1 1 0 1 1 1 1 MRG Chromo PF00385.24 CBY07434.1 - 0.018 14.9 4.3 0.018 14.9 4.3 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain zf-C2H2 PF00096.26 CBY07436.1 - 6.8e-08 32.5 11.4 0.00032 21.0 0.3 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY07436.1 - 0.00058 20.5 6.8 0.37 11.7 0.2 3.0 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CBY07436.1 - 0.12 12.5 1.7 0.27 11.4 1.7 1.6 1 1 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 CBY07436.1 - 1.2 9.7 9.8 0.95 10.0 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBY07436.1 - 2.7 7.8 14.7 0.15 11.9 2.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain EF-hand_1 PF00036.32 CBY07437.1 - 8.8e-05 21.8 0.5 0.00071 18.9 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CBY07437.1 - 0.00014 22.3 0.4 0.047 14.1 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY07437.1 - 0.00027 20.6 0.4 0.0035 17.1 0.1 2.9 4 1 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 CBY07437.1 - 0.0007 19.0 0.2 0.0036 16.7 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBY07437.1 - 0.0082 16.0 0.0 0.063 13.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair RhoGEF PF00621.20 CBY07440.1 - 9.1e-31 107.5 1.0 1.3e-30 107.0 1.0 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 CBY07440.1 - 0.0067 16.9 0.7 0.02 15.4 0.1 2.1 2 0 0 2 2 2 1 PH domain EF-hand_1 PF00036.32 CBY07441.1 - 5.2e-08 31.9 2.3 7.1e-05 22.1 0.4 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY07441.1 - 1.2e-05 25.7 1.4 0.03 14.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY07441.1 - 0.0003 20.5 7.6 0.0068 16.3 0.7 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY07441.1 - 0.0004 19.8 0.6 0.0004 19.8 0.6 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY07441.1 - 0.0032 17.3 0.4 0.059 13.2 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY07442.1 - 2.9e-08 32.7 2.2 2.2e-05 23.7 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY07442.1 - 9.5e-07 28.0 4.7 8.8e-06 25.0 0.4 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY07442.1 - 3.9e-06 26.4 3.6 0.0015 18.3 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY07442.1 - 9.9e-05 22.7 2.2 0.0022 18.4 2.2 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY07442.1 - 0.00022 21.0 1.6 0.046 13.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair ABC_tran PF00005.27 CBY07443.1 - 1.4e-51 174.6 0.0 2.5e-28 99.3 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CBY07443.1 - 1.1e-22 81.3 0.1 9e-07 29.0 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 CBY07443.1 - 4.7e-18 65.4 6.8 4.7e-18 65.4 6.8 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CBY07443.1 - 3.9e-09 36.6 0.2 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CBY07443.1 - 1.7e-08 34.0 0.9 0.0015 18.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CBY07443.1 - 4.8e-08 32.7 0.0 0.28 10.6 0.0 4.3 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CBY07443.1 - 1.4e-06 28.3 10.9 0.01 15.6 2.5 4.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBY07443.1 - 3.3e-05 24.2 0.1 0.24 11.7 0.0 3.3 3 2 0 3 3 2 2 AAA domain AAA_23 PF13476.6 CBY07443.1 - 9.1e-05 23.0 17.9 0.00063 20.3 0.4 3.9 4 1 1 5 5 4 2 AAA domain IstB_IS21 PF01695.17 CBY07443.1 - 9.7e-05 22.2 0.1 1.9 8.2 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_30 PF13604.6 CBY07443.1 - 0.00044 20.0 0.1 1.1 8.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CBY07443.1 - 0.00049 20.1 1.1 0.38 10.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 CBY07443.1 - 0.00072 19.6 0.3 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 CBY07443.1 - 0.0014 18.5 0.3 0.04 13.7 0.1 2.5 2 0 0 2 2 2 1 MukB N-terminal AAA_16 PF13191.6 CBY07443.1 - 0.0015 19.0 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 CBY07443.1 - 0.0021 17.8 0.2 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CBY07443.1 - 0.0022 18.4 3.1 0.11 13.0 0.1 3.5 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 CBY07443.1 - 0.0033 17.0 0.1 0.59 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBY07443.1 - 0.0039 17.7 0.4 5.6 7.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBY07443.1 - 0.0051 17.2 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 CBY07443.1 - 0.0096 15.9 0.9 1.2 9.0 0.1 3.0 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_28 PF13521.6 CBY07443.1 - 0.015 15.6 2.2 4.8 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBY07443.1 - 0.018 15.2 0.5 5.7 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CBY07443.1 - 0.033 14.3 0.2 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 CBY07443.1 - 0.035 14.0 2.3 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CBY07443.1 - 0.038 13.6 0.7 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain NAD_binding_7 PF13241.6 CBY07443.1 - 0.042 14.3 0.1 0.096 13.1 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Mg_chelatase PF01078.21 CBY07443.1 - 0.05 13.0 0.0 9.7 5.5 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 CBY07443.1 - 0.092 13.0 0.1 2.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 CBY07443.1 - 0.094 11.3 4.6 2.1 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 CBY07443.1 - 0.1 12.2 0.3 0.2 11.3 0.0 1.7 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3584 PF12128.8 CBY07443.1 - 0.1 10.1 1.2 0.83 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Cas_DxTHG PF09455.10 CBY07443.1 - 0.14 11.7 3.3 1.1 8.8 0.3 2.3 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family AAA_14 PF13173.6 CBY07443.1 - 0.32 11.0 2.1 54 3.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 CBY07443.1 - 0.44 10.1 4.8 8.4 6.0 0.1 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CBY07443.1 - 0.75 9.7 6.0 22 4.9 0.1 4.3 5 0 0 5 5 5 0 NTPase cobW PF02492.19 CBY07443.1 - 1.1 8.9 3.1 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_hydro_31 PF01055.26 CBY07444.1 - 2.8e-116 389.3 0.9 3.9e-116 388.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CBY07444.1 - 0.0032 17.8 0.1 0.011 16.0 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Trefoil PF00088.18 CBY07444.1 - 0.037 13.9 3.5 0.099 12.5 3.5 1.8 1 0 0 1 1 1 0 Trefoil (P-type) domain Kinocilin PF15033.6 CBY07447.1 - 0.25 11.0 1.2 0.58 9.8 0.1 1.9 2 0 0 2 2 2 0 Kinocilin protein Trypsin PF00089.26 CBY07448.1 - 2.2e-39 135.6 0.4 2.8e-39 135.2 0.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY07448.1 - 1.8e-06 28.9 0.0 3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY07448.1 - 0.0019 18.6 0.0 0.003 17.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Connexin PF00029.19 CBY07449.1 - 4.3e-25 88.8 3.0 2.7e-20 73.1 1.4 2.1 2 0 0 2 2 2 2 Connexin Avian_gp85 PF03708.14 CBY07449.1 - 0.0061 15.8 0.5 0.013 14.7 0.5 1.5 1 0 0 1 1 1 1 Avian retrovirus envelope protein, gp85 Lectin_C PF00059.21 CBY07450.1 - 1.4e-11 45.1 1.2 3e-11 44.0 1.2 1.6 1 0 0 1 1 1 1 Lectin C-type domain DUF2975 PF11188.8 CBY07451.1 - 3.5 7.5 8.3 0.51 10.2 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) TPR_19 PF14559.6 CBY07452.1 - 0.0032 17.9 1.9 0.0049 17.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat SEP PF08059.13 CBY07452.1 - 0.036 14.6 0.3 0.74 10.4 0.0 2.6 3 0 0 3 3 3 0 SEP domain ThiF PF00899.21 CBY07453.1 - 1.7e-61 207.7 0.0 2.4e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 CBY07453.1 - 6e-15 55.2 0.6 1e-14 54.4 0.6 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 CBY07453.1 - 0.006 17.2 0.3 0.012 16.1 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain PglD_N PF17836.1 CBY07453.1 - 0.015 15.9 0.1 0.17 12.6 0.1 2.7 2 0 0 2 2 2 0 PglD N-terminal domain Sulfotransfer_3 PF13469.6 CBY07455.1 - 2e-10 41.5 0.0 0.0063 16.9 0.0 3.5 2 1 1 3 3 3 3 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY07455.1 - 1.1e-08 34.9 0.0 5.8e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Peripla_BP_1 PF00532.21 CBY07455.1 - 7.8e-05 22.2 0.0 0.00017 21.2 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family CSTF2_hinge PF14327.6 CBY07455.1 - 0.12 12.8 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 IU_nuc_hydro PF01156.19 CBY07455.1 - 0.23 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase E1-E2_ATPase PF00122.20 CBY07456.1 - 1.5e-46 158.2 0.7 1.5e-46 158.2 0.7 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBY07456.1 - 6.7e-42 143.3 1.9 6.7e-42 143.3 1.9 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CBY07456.1 - 5.3e-25 87.3 0.0 1e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY07456.1 - 3.7e-20 73.1 0.1 1.3e-19 71.3 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBY07456.1 - 5.5e-16 58.0 0.0 1.3e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBY07456.1 - 5.6e-07 29.6 0.9 0.00069 19.4 0.6 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY07456.1 - 0.00026 21.4 0.1 0.00078 19.9 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 CBY07456.1 - 1.1 9.3 7.8 9.1 6.4 5.8 2.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MgtE PF01769.16 CBY07456.1 - 5.3 7.4 11.6 3.1 8.2 3.1 3.4 3 1 0 3 3 3 0 Divalent cation transporter DAGK_acc PF00609.19 CBY07457.1 - 2.2e-34 119.1 0.0 3.4e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBY07457.1 - 3.8e-27 94.4 0.0 6.1e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CBY07457.1 - 0.00046 20.0 18.1 0.0012 18.6 3.4 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 CBY07457.1 - 0.018 15.0 5.6 0.027 14.5 1.0 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid PHD PF00628.29 CBY07457.1 - 0.14 12.0 12.1 0.1 12.5 0.8 3.1 3 0 0 3 3 3 0 PHD-finger C1_2 PF03107.16 CBY07457.1 - 2.1 8.7 10.8 2.6 8.4 0.7 3.0 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.6 CBY07457.1 - 3.3 7.4 10.1 0.87 9.2 2.6 2.7 2 0 0 2 2 2 0 PHD-finger Strabismus PF06638.11 CBY07458.1 - 9.6e-134 446.8 1.9 1.2e-133 446.5 1.9 1.0 1 0 0 1 1 1 1 Strabismus protein DUF2842 PF11003.8 CBY07458.1 - 0.47 10.7 5.3 1.1 9.6 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) NTP_transf_7 PF07984.12 CBY07460.1 - 2e-127 424.9 1.6 2.8e-127 424.4 1.6 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase Neur_chan_LBD PF02931.23 CBY07460.1 - 2.8e-40 138.1 1.1 6.6e-40 136.9 1.1 1.7 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY07460.1 - 5.8e-13 49.5 11.8 6.8e-12 45.9 11.8 2.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ASC PF00858.24 CBY07460.1 - 0.0075 15.3 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Peptidase_S49_N PF08496.10 CBY07460.1 - 7.8 6.5 8.2 49 4.0 5.7 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CUB PF00431.20 CBY07462.1 - 0.0023 18.3 1.6 0.0032 17.8 1.6 1.3 1 0 0 1 1 1 1 CUB domain zf-C4 PF00105.18 CBY07463.1 - 7e-32 109.7 12.4 1.3e-31 108.9 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY07463.1 - 9.8e-08 31.8 0.3 3.1e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DUF3736 PF12540.8 CBY07463.1 - 9.1 6.4 12.8 0.25 11.4 3.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3736) ITI_HC_C PF06668.12 CBY07464.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus DUF3439 PF11921.8 CBY07464.1 - 0.017 15.1 2.2 0.028 14.4 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glycoprotein_G PF00802.19 CBY07464.1 - 0.79 9.0 14.0 1.2 8.4 14.0 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Trypsin PF00089.26 CBY07465.1 - 3.2e-13 50.0 0.0 5.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin EGF_CA PF07645.15 CBY07466.1 - 4.8e-06 26.7 2.5 4.8e-06 26.7 2.5 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 CBY07466.1 - 0.48 10.8 14.5 0.82 10.0 6.4 2.7 3 0 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.6 CBY07466.1 - 1.8 8.9 8.6 8.2 6.8 3.6 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY07466.1 - 3.8 8.3 14.6 7.2 7.4 5.3 3.4 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_3 PF12947.7 CBY07466.1 - 5 7.4 10.0 14 6.0 4.0 2.4 2 0 0 2 2 2 0 EGF domain GAGE PF05831.11 CBY07467.1 - 0.14 12.7 4.2 0.3 11.6 0.8 2.8 1 1 1 2 2 2 0 GAGE protein Acetyltransf_10 PF13673.7 CBY07468.1 - 1.4e-05 25.0 0.1 2.3e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY07468.1 - 7.1e-05 23.0 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY07468.1 - 0.00026 21.3 0.0 0.00037 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY07468.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CBY07468.1 - 0.11 12.6 0.0 0.38 10.8 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Ras PF00071.22 CBY07469.1 - 2.2e-24 85.9 0.0 1.4e-23 83.2 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBY07469.1 - 3.2e-12 46.7 0.0 1.2e-11 44.9 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY07469.1 - 3.6e-06 26.5 0.1 6e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY07469.1 - 2.9e-05 23.7 0.0 0.00015 21.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY07469.1 - 0.0011 19.1 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY07469.1 - 0.0016 18.4 1.9 2.1 8.2 0.0 3.0 2 1 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 CBY07469.1 - 0.0046 16.5 0.4 0.2 11.2 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CBY07469.1 - 0.022 14.5 0.3 2.7 7.7 0.0 2.9 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 CBY07469.1 - 0.13 12.3 0.1 0.87 9.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain SEA PF01390.20 CBY07470.1 - 0.031 14.4 0.6 0.095 12.8 0.1 2.0 2 0 0 2 2 2 0 SEA domain TSP_1 PF00090.19 CBY07471.1 - 3.5e-20 71.9 55.3 3.6e-08 33.5 12.9 3.9 3 0 0 3 3 3 3 Thrombospondin type 1 domain CAP PF00188.26 CBY07471.1 - 8.5e-15 55.7 0.1 8.5e-15 55.7 0.1 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family zf-RING_5 PF14634.6 CBY07473.1 - 0.031 14.2 0.2 0.074 13.0 0.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF202 PF02656.15 CBY07474.1 - 0.17 12.4 3.1 0.84 10.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase_Tyr PF07714.17 CBY07475.1 - 2e-61 207.6 0.0 3.4e-61 206.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY07475.1 - 1e-31 110.3 0.0 4.1e-31 108.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain 4HB_MCP_1 PF12729.7 CBY07475.1 - 0.0077 15.8 0.2 0.047 13.2 0.1 2.3 1 1 1 2 2 2 1 Four helix bundle sensory module for signal transduction DUF2681 PF10883.8 CBY07475.1 - 0.015 15.7 1.4 0.015 15.7 1.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) TarH PF02203.15 CBY07475.1 - 0.1 12.5 0.1 0.92 9.4 0.0 2.3 1 1 1 2 2 2 0 Tar ligand binding domain homologue Astacin PF01400.24 CBY07476.1 - 7.1e-29 100.8 0.1 1.3e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY07476.1 - 0.0019 18.4 8.0 0.0019 18.4 8.0 4.0 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A VipB PF05943.12 CBY07477.1 - 0.011 14.5 0.0 0.012 14.5 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion protein, EvpB/VC_A0108, tail sheath zf-LITAF-like PF10601.9 CBY07477.1 - 0.036 14.3 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Peptidase_M14 PF00246.24 CBY07478.1 - 7.4e-67 226.2 0.9 1e-66 225.7 0.9 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY07478.1 - 0.00032 21.0 0.1 0.00067 20.0 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide CUB PF00431.20 CBY07479.1 - 1.2e-11 44.9 0.9 6.2e-10 39.4 0.9 2.5 1 1 0 1 1 1 1 CUB domain EGF_3 PF12947.7 CBY07480.1 - 9.9e-46 153.6 91.7 1e-09 38.4 8.6 5.2 5 0 0 5 5 5 5 EGF domain EGF_CA PF07645.15 CBY07480.1 - 4.2e-37 126.1 88.6 5e-10 39.4 13.7 6.2 6 0 0 6 6 6 6 Calcium-binding EGF domain cEGF PF12662.7 CBY07480.1 - 3.1e-23 81.3 49.1 5.5e-07 29.4 4.7 5.9 5 0 0 5 5 5 5 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY07480.1 - 5.3e-16 58.4 72.9 6.8e-07 29.2 6.4 6.2 6 0 0 6 6 6 5 MSP1 EGF domain 1 EGF PF00008.27 CBY07480.1 - 8.6e-16 57.9 68.5 0.00013 22.2 7.3 6.9 5 2 1 6 6 6 5 EGF-like domain hEGF PF12661.7 CBY07480.1 - 3.6e-07 30.6 74.5 0.00052 20.6 3.2 8.3 8 2 0 8 8 8 5 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY07480.1 - 4.5e-06 26.8 72.7 0.061 13.6 10.3 5.4 3 2 2 5 5 5 5 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY07480.1 - 0.00014 22.1 66.9 0.045 14.1 7.6 6.3 5 1 0 6 6 6 3 Pvs28 EGF domain DUF3439 PF11921.8 CBY07480.1 - 0.32 11.0 14.0 0.96 9.4 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CBY07480.1 - 1.9 6.3 5.1 1.2 7.0 0.2 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Tetraspanin PF00335.20 CBY07482.1 - 6.8e-48 163.4 3.3 7.8e-48 163.2 3.3 1.0 1 0 0 1 1 1 1 Tetraspanin family Neurensin PF14927.6 CBY07482.1 - 0.11 12.2 2.5 0.25 11.0 0.0 2.5 3 0 0 3 3 3 0 Neurensin DUF373 PF04123.13 CBY07482.1 - 0.31 10.4 4.0 0.52 9.7 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Phage_holin_5_2 PF16079.5 CBY07482.1 - 1.7 9.0 6.8 0.46 10.8 1.7 2.6 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V FtsX PF02687.21 CBY07482.1 - 5 7.7 16.6 5.6 7.5 5.2 2.9 1 1 1 2 2 2 0 FtsX-like permease family zf-met PF12874.7 CBY07483.1 - 3e-08 33.8 1.5 5.3e-08 33.0 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY07483.1 - 4.6e-07 29.9 0.4 8.7e-07 29.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RNase_T PF00929.24 CBY07483.1 - 0.00015 22.4 0.0 0.00081 20.0 0.0 2.0 1 1 0 1 1 1 1 Exonuclease zf-C2H2 PF00096.26 CBY07483.1 - 0.012 16.0 0.5 0.012 16.0 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_pol_A_exo1 PF01612.20 CBY07483.1 - 0.014 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease zf-U1 PF06220.12 CBY07483.1 - 0.015 15.1 1.3 0.034 13.9 1.3 1.6 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.6 CBY07483.1 - 0.04 14.8 0.2 0.13 13.2 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger GAGA PF09237.11 CBY07483.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 GAGA factor RPE65 PF03055.15 CBY07484.1 - 3.7e-53 181.4 0.1 5.2e-53 180.9 0.1 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TPR_8 PF13181.6 CBY07485.1 - 2.3e-15 55.4 9.3 0.12 12.7 0.0 8.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBY07485.1 - 8.5e-13 47.4 12.6 0.25 11.6 0.1 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY07485.1 - 8.5e-08 31.7 8.1 0.65 9.9 0.0 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY07485.1 - 2.7e-07 30.8 4.9 3 8.9 0.0 7.7 9 1 1 10 10 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY07485.1 - 9.5e-07 28.4 1.6 0.012 15.2 0.0 5.7 6 0 0 6 6 6 1 TPR repeat TPR_6 PF13174.6 CBY07485.1 - 0.00042 20.8 4.9 20 6.1 0.0 6.7 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY07485.1 - 0.00065 19.9 20.3 2.3 8.5 0.0 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY07485.1 - 0.0012 18.7 6.6 8.8 6.6 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY07485.1 - 0.022 14.9 0.1 18 5.5 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY07485.1 - 0.046 14.1 4.5 89 3.8 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 CBY07485.1 - 0.073 13.1 3.6 2.1 8.4 0.3 4.2 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 CBY07485.1 - 0.17 12.4 10.0 1.9 9.1 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY07485.1 - 0.17 12.1 10.7 27 5.1 0.1 5.2 6 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Band_7_C PF16200.5 CBY07485.1 - 0.18 11.9 0.0 0.98 9.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of band_7 TPR_10 PF13374.6 CBY07485.1 - 1.8 8.5 9.2 15 5.6 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat HECT PF00632.25 CBY07488.1 - 2.2e-86 290.1 0.0 4.5e-86 289.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW1_helix PF18436.1 CBY07488.1 - 2.1e-06 27.7 3.1 5.9e-06 26.3 3.1 1.8 1 0 0 1 1 1 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 Ost5 PF05251.12 CBY07489.1 - 2.2e-22 79.1 4.2 2.4e-22 79.0 4.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Ndr PF03096.14 CBY07490.1 - 1.4e-65 220.8 0.0 1.8e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 CBY07490.1 - 0.00051 19.4 0.0 0.0016 17.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY07490.1 - 0.00096 18.9 0.0 0.0048 16.6 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.11 CBY07490.1 - 0.12 11.2 0.1 0.74 8.6 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) Cmyb_C PF09316.10 CBY07491.1 - 1.5e-10 41.0 0.1 3.6e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 C-myb, C-terminal DUF3704 PF12488.8 CBY07491.1 - 0.14 11.8 0.3 0.14 11.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Laminin_G_2 PF02210.24 CBY07492.1 - 2.2e-07 31.5 0.4 2.8e-05 24.7 0.0 2.7 2 1 0 2 2 2 2 Laminin G domain PA-IIL PF07472.11 CBY07492.1 - 0.13 12.5 0.4 0.41 11.0 0.1 1.9 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) zf-RING_5 PF14634.6 CBY07493.1 - 8e-06 25.7 3.9 2.1e-05 24.4 3.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY07493.1 - 0.0041 17.1 1.2 0.0041 17.1 1.2 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY07493.1 - 0.041 13.7 0.6 0.041 13.7 0.6 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY07493.1 - 0.32 10.9 7.3 0.13 12.1 1.1 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBY07493.1 - 0.37 10.7 4.8 0.47 10.4 0.5 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CBY07493.1 - 1.2 9.6 7.0 1.4 9.3 3.0 2.7 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 CBY07493.1 - 4 7.7 10.0 0.13 12.5 1.6 2.6 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING TetR_C_14 PF17754.1 CBY07495.1 - 0.14 12.1 0.4 0.27 11.2 0.4 1.4 1 0 0 1 1 1 0 MftR C-terminal domain MYEOV2 PF15004.6 CBY07497.1 - 0.036 14.5 0.1 0.09 13.2 0.0 1.7 2 0 0 2 2 2 0 Myeloma-overexpressed-like Spore_IV_A PF09547.10 CBY07497.1 - 0.065 12.2 0.0 0.078 11.9 0.0 1.0 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Gemini_AL1_M PF08283.11 CBY07497.1 - 0.14 12.2 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Geminivirus rep protein central domain Dak2 PF02734.17 CBY07498.1 - 0.01 15.7 3.4 0.012 15.5 3.4 1.2 1 0 0 1 1 1 0 DAK2 domain Complex1_LYR_2 PF13233.6 CBY07498.1 - 0.073 13.8 2.5 0.091 13.5 2.1 1.5 1 1 0 1 1 1 0 Complex1_LYR-like ATP-synt_B PF00430.18 CBY07498.1 - 0.097 12.8 14.0 0.14 12.3 14.0 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Ribosomal_S5 PF00333.20 CBY07498.1 - 0.11 12.5 11.1 0.15 12.1 0.7 2.5 1 1 1 2 2 2 0 Ribosomal protein S5, N-terminal domain MCU PF04678.13 CBY07498.1 - 0.39 10.8 3.9 0.46 10.6 3.9 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4337 PF14235.6 CBY07498.1 - 0.46 10.6 13.0 0.55 10.3 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Fzo_mitofusin PF04799.13 CBY07498.1 - 0.46 10.0 4.0 0.61 9.6 4.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region Mit_KHE1 PF10173.9 CBY07498.1 - 0.5 10.4 8.7 0.57 10.2 8.7 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related NARP1 PF12569.8 CBY07498.1 - 0.87 8.4 17.4 1.1 8.1 17.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dodecin PF07311.12 CBY07498.1 - 0.92 9.8 6.8 2.4 8.5 0.8 2.3 1 1 1 2 2 2 0 Dodecin TMPIT PF07851.13 CBY07498.1 - 1.4 8.1 6.7 1.6 7.9 6.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3987 PF13148.6 CBY07498.1 - 1.9 7.4 10.8 2.3 7.2 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Oleosin PF01277.17 CBY07498.1 - 3.3 7.5 4.6 3.8 7.3 3.2 1.7 1 1 1 2 2 2 0 Oleosin DUF4407 PF14362.6 CBY07498.1 - 3.7 6.8 16.2 4.7 6.5 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF982 PF06169.12 CBY07498.1 - 4.4 7.4 6.7 0.66 10.1 3.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF982) V_ATPase_I PF01496.19 CBY07498.1 - 5.4 4.8 9.3 5.6 4.8 9.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Spc19 PF08287.11 CBY07498.1 - 6.3 6.7 15.8 7.8 6.4 15.8 1.2 1 0 0 1 1 1 0 Spc19 DNA_pack_N PF02500.15 CBY07500.1 - 0.0035 17.2 0.7 0.0051 16.7 0.7 1.3 1 0 0 1 1 1 1 Probable DNA packing protein, N-terminus Gal-3-0_sulfotr PF06990.11 CBY07501.1 - 1.5e-16 60.3 0.0 1.6e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Gal-3-0_sulfotr PF06990.11 CBY07503.1 - 1.8e-45 155.6 0.0 2.2e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_3 PF13469.6 CBY07503.1 - 0.0026 18.2 0.0 0.0069 16.8 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family PHINT_rpt PF14882.6 CBY07503.1 - 0.099 12.9 4.4 5.4 7.4 0.2 3.2 3 0 0 3 3 3 0 Phage-integrase repeat unit DUF1726 PF08351.11 CBY07503.1 - 0.19 11.7 2.1 1.2 9.1 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1726) Synaptobrevin PF00957.21 CBY07506.1 - 0.068 13.0 0.2 0.068 13.0 0.2 2.6 3 0 0 3 3 3 0 Synaptobrevin VWA_3 PF13768.6 CBY07506.1 - 0.098 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Sulfotransfer_4 PF17784.1 CBY07508.1 - 1.4e-43 149.3 0.2 1.8e-43 148.9 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY07508.1 - 0.042 14.2 0.1 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_4 PF17784.1 CBY07509.1 - 1.1e-34 120.1 1.2 1.5e-34 119.7 1.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY07509.1 - 0.0013 19.2 0.1 0.0043 17.5 0.0 1.9 1 1 0 2 2 2 1 Sulfotransferase family PORR PF11955.8 CBY07510.1 - 0.065 12.2 0.7 0.16 10.9 0.1 1.9 2 0 0 2 2 2 0 Plant organelle RNA recognition domain NOT2_3_5 PF04153.18 CBY07511.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.0 1 1 1 2 2 2 0 NOT2 / NOT3 / NOT5 family An_peroxidase PF03098.15 CBY07512.1 - 2.8e-118 395.8 0.0 3.5e-118 395.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Y_phosphatase PF00102.27 CBY07513.1 - 1.2e-67 228.0 0.1 1.8e-67 227.3 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY07513.1 - 0.00019 21.5 0.0 0.00044 20.3 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CBY07513.1 - 0.00088 19.1 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY07513.1 - 0.0056 16.8 3.6 0.023 14.8 0.0 3.0 2 2 1 3 3 3 1 Inositol hexakisphosphate GTP-bdg_M PF16360.5 CBY07513.1 - 0.021 15.4 1.0 0.047 14.3 1.0 1.5 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region zf-CCHC PF00098.23 CBY07514.1 - 0.00063 19.7 2.3 0.00063 19.7 2.3 5.3 5 1 0 5 5 5 2 Zinc knuckle RRM_1 PF00076.22 CBY07515.1 - 0.013 15.4 0.0 0.044 13.6 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY07515.1 - 0.028 14.5 2.0 0.11 12.6 0.3 2.5 3 0 0 3 3 3 0 RNA binding motif LRR_6 PF13516.6 CBY07516.1 - 0.00023 21.0 1.2 0.82 9.9 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat OST-HTH PF12872.7 CBY07516.1 - 0.016 15.0 0.2 1.5 8.7 0.0 3.4 4 0 0 4 4 4 0 OST-HTH/LOTUS domain Myb_DNA-bind_4 PF13837.6 CBY07516.1 - 0.041 14.2 0.9 0.17 12.3 0.8 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lipase_GDSL_3 PF14606.6 CBY07516.1 - 0.27 11.3 0.0 0.27 11.3 0.0 2.5 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family DUF4533 PF15047.6 CBY07516.1 - 0.78 9.3 7.2 0.12 11.9 1.1 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4533) LRR_1 PF00560.33 CBY07516.1 - 4.2 8.3 6.2 2.3e+02 3.0 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat GA-like PF17573.2 CBY07517.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 GA-like domain GH114_assoc PF14741.6 CBY07519.1 - 0.012 15.8 1.2 0.034 14.3 1.2 1.8 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain 7tm_1 PF00001.21 CBY07520.1 - 2.3e-17 63.2 1.0 3e-17 62.8 1.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_A14 PF05767.12 CBY07520.1 - 1.5 9.1 6.2 1 9.5 1.1 2.7 1 1 2 3 3 3 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.21 CBY07521.1 - 7e-05 22.3 0.1 7e-05 22.3 0.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DnaJ PF00226.31 CBY07523.1 - 1.9e-11 43.9 0.7 4.1e-11 42.9 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain MLANA PF14991.6 CBY07525.1 - 0.00037 20.8 0.4 0.0027 18.0 0.0 2.3 2 0 0 2 2 2 1 Protein melan-A DUF4446 PF14584.6 CBY07525.1 - 0.33 10.9 3.2 2.1 8.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF4199 PF13858.6 CBY07525.1 - 0.62 10.4 1.9 3.6 8.0 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) IPK PF03770.16 CBY07526.1 - 5e-26 91.8 3.7 3.2e-25 89.1 3.7 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase Birna_RdRp PF04197.12 CBY07526.1 - 0.012 14.0 0.5 0.017 13.5 0.5 1.2 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) SSF PF00474.17 CBY07527.1 - 1.1e-42 146.4 17.2 1.4e-42 146.0 17.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family COX14 PF14880.6 CBY07527.1 - 0.12 12.2 0.7 0.69 9.8 0.0 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Aminotran_5 PF00266.19 CBY07528.1 - 3.3e-27 95.4 0.0 6e-27 94.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CBY07528.1 - 0.00011 21.5 0.4 0.019 14.2 0.1 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Ldl_recept_a PF00057.18 CBY07529.1 - 6.2e-09 35.9 18.6 1.3e-08 34.9 10.9 2.4 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A TPR_2 PF07719.17 CBY07531.1 - 2.9e-11 42.6 12.9 0.13 12.4 0.1 7.7 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY07531.1 - 2.5e-07 30.9 16.4 0.0019 18.5 0.5 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY07531.1 - 1.1e-06 28.2 10.4 0.049 13.5 0.4 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.6 CBY07531.1 - 6.1e-06 25.9 0.3 6.1e-06 25.9 0.3 3.1 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 CBY07531.1 - 6.5e-06 26.5 8.3 6.7 7.8 0.2 6.5 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY07531.1 - 4.2e-05 23.4 6.5 0.17 12.2 0.3 5.9 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY07531.1 - 0.00013 22.5 9.2 0.98 10.1 0.9 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY07531.1 - 0.00014 22.3 10.5 1.3 9.5 1.5 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY07531.1 - 0.00017 21.7 10.7 0.011 15.9 0.6 5.1 5 1 1 6 6 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBY07531.1 - 0.00051 20.5 9.9 4.2 8.2 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY07531.1 - 0.00091 18.9 1.4 4.8 7.0 0.0 4.1 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.6 CBY07531.1 - 0.077 13.1 5.1 5.8 7.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ComR_TPR PF18710.1 CBY07531.1 - 0.26 10.8 3.8 4.3 6.8 0.3 2.9 2 1 1 3 3 3 0 ComR tetratricopeptide DUF2786 PF10979.8 CBY07531.1 - 0.32 10.9 5.0 3.9 7.5 0.9 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2786) DUF2802 PF10975.8 CBY07531.1 - 9 6.5 9.4 2.4 8.3 2.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DHR-2 PF06920.13 CBY07532.1 - 4.8e-127 424.8 15.6 6.9e-104 348.4 5.9 3.9 4 0 0 4 4 4 2 Dock homology region 2 DOCK-C2 PF14429.6 CBY07532.1 - 1.3e-34 119.8 0.1 1.6e-33 116.2 0.1 2.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 CBY07532.1 - 1.3e-11 44.9 0.3 5e-11 43.0 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 CBY07532.1 - 1.4e-06 28.8 2.0 4.5e-06 27.1 0.4 2.7 2 0 0 2 2 2 1 PH domain HWE_HK PF07536.14 CBY07532.1 - 0.083 13.6 0.3 0.36 11.6 0.3 2.1 1 0 0 1 1 1 0 HWE histidine kinase YIEGIA PF14045.6 CBY07532.1 - 0.17 10.7 0.1 0.35 9.7 0.1 1.4 1 0 0 1 1 1 0 YIEGIA protein Sulfotransfer_2 PF03567.14 CBY07533.1 - 1.1e-13 51.7 0.5 2.3e-13 50.7 0.5 1.5 1 0 0 1 1 1 1 Sulfotransferase family GMP_synt_C PF00958.22 CBY07534.1 - 0.015 15.4 0.1 0.14 12.3 0.0 2.4 2 1 1 3 3 3 0 GMP synthase C terminal domain Phospholip_A2_1 PF00068.19 CBY07535.1 - 1.1e-17 64.5 8.2 1.1e-17 64.5 8.2 1.7 2 0 0 2 2 2 1 Phospholipase A2 Ldh_2 PF02615.14 CBY07536.1 - 1.4e-80 270.9 1.2 1.7e-80 270.7 1.2 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase EGF_CA PF07645.15 CBY07539.1 - 1.4e-159 518.1 534.5 1.3e-09 38.1 8.6 38.2 31 8 7 38 38 38 30 Calcium-binding EGF domain EGF_3 PF12947.7 CBY07539.1 - 7.7e-81 266.0 430.9 6e-09 36.0 10.9 35.7 33 2 3 36 36 36 25 EGF domain cEGF PF12662.7 CBY07539.1 - 1.7e-75 248.5 293.6 2.3e-05 24.2 0.7 34.7 34 0 0 34 34 34 26 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY07539.1 - 2.5e-16 59.6 414.9 0.0021 18.3 1.4 35.4 28 5 7 35 35 35 18 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY07539.1 - 1.5e-11 44.4 433.0 0.00048 20.4 3.4 36.4 35 3 3 38 38 38 20 EGF-like domain hEGF PF12661.7 CBY07539.1 - 2.6e-05 24.7 375.9 0.0089 16.6 1.9 38.5 37 1 0 37 37 37 19 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY07539.1 - 4.3e-05 23.5 7.1 0.00015 21.7 1.6 32.8 31 4 3 34 34 34 15 MSP1 EGF domain 1 Sugar_tr PF00083.24 CBY07540.1 - 2.8e-63 214.4 15.2 6.4e-63 213.2 15.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY07540.1 - 5.7e-07 28.8 20.8 2.1e-06 26.9 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF373 PF04123.13 CBY07540.1 - 0.08 12.4 1.2 0.13 11.7 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4181 PF13789.6 CBY07540.1 - 1.1 9.6 7.0 0.44 10.8 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) GAS PF13851.6 CBY07541.1 - 0.0016 17.8 8.2 0.0016 17.8 8.2 20.9 3 1 17 21 21 21 7 Growth-arrest specific micro-tubule binding HypA PF01155.19 CBY07541.1 - 0.01 15.9 0.4 0.45 10.6 0.2 3.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Neur_chan_LBD PF02931.23 CBY07543.1 - 4e-44 150.6 0.2 5.2e-44 150.3 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY07543.1 - 4.8e-23 82.5 2.8 8.2e-23 81.7 2.8 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Phospholip_A2_1 PF00068.19 CBY07544.1 - 0.0076 16.7 2.7 0.0076 16.7 2.7 1.7 2 0 0 2 2 2 1 Phospholipase A2 zf-RING_2 PF13639.6 CBY07546.1 - 4.7e-10 39.6 8.4 4.7e-10 39.6 8.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CBY07546.1 - 2.3e-09 36.8 4.4 5.3e-09 35.7 4.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CBY07546.1 - 8.6e-06 25.6 8.5 8.6e-06 25.6 8.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY07546.1 - 0.00026 20.8 10.3 0.00026 20.8 10.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY07546.1 - 0.00071 19.4 8.7 0.00071 19.4 8.7 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY07546.1 - 0.00087 19.5 8.4 0.00087 19.5 8.4 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBY07546.1 - 0.00098 19.1 4.2 0.00098 19.1 4.2 2.7 2 1 1 3 3 3 1 RING-type zinc-finger Baculo_IE-1 PF05290.11 CBY07546.1 - 0.0053 16.7 1.9 0.0053 16.7 1.9 1.7 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 CBY07546.1 - 0.0061 16.4 2.7 0.0061 16.4 2.7 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY07546.1 - 0.028 14.3 8.7 0.028 14.3 8.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY07546.1 - 0.037 13.9 7.8 0.037 13.9 7.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CBY07546.1 - 0.038 13.8 5.4 0.072 12.9 5.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE_2 PF02318.16 CBY07546.1 - 0.13 12.4 7.6 1.1 9.5 0.3 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_10 PF16685.5 CBY07546.1 - 1.8 8.8 13.0 3.7 7.8 7.0 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 PHD PF00628.29 CBY07546.1 - 5.9 6.9 20.4 1.9 8.5 8.0 3.4 2 2 1 3 3 3 0 PHD-finger Zf_RING PF16744.5 CBY07546.1 - 6.9 6.9 16.6 3.8 7.7 5.4 2.8 2 1 0 2 2 2 0 KIAA1045 RING finger Pkinase_Tyr PF07714.17 CBY07547.1 - 1.9e-18 66.7 0.1 6e-17 61.8 0.1 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY07547.1 - 2.2e-07 30.5 0.2 7.7e-07 28.7 0.2 1.9 1 1 0 1 1 1 1 Protein kinase domain Asp PF00026.23 CBY07548.1 - 2.2e-96 323.0 0.0 2.6e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CBY07548.1 - 2.2e-11 44.3 0.1 4.6e-10 40.0 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CBY07548.1 - 7.9e-05 22.5 0.0 0.00026 20.8 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal MtrF PF09472.10 CBY07548.1 - 0.081 12.3 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) P2_N PF18628.1 CBY07549.1 - 0.018 14.8 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain Mucin PF01456.17 CBY07550.1 - 5.8e-06 26.3 23.9 5.8e-06 26.3 23.9 1.9 2 0 0 2 2 2 1 Mucin-like glycoprotein SprA-related PF12118.8 CBY07550.1 - 0.17 11.0 4.4 0.15 11.1 4.4 1.1 1 0 0 1 1 1 0 SprA-related family MAP65_ASE1 PF03999.12 CBY07550.1 - 0.19 10.4 2.3 0.24 10.0 2.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FSA_C PF10479.9 CBY07550.1 - 0.41 8.7 12.5 0.45 8.6 12.5 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AJAP1_PANP_C PF15298.6 CBY07550.1 - 0.68 10.1 21.2 1.1 9.5 21.2 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Somatomedin_B PF01033.17 CBY07550.1 - 1.6 9.2 24.0 1.3 9.5 22.6 1.7 1 1 0 1 1 1 0 Somatomedin B domain Trypsin PF00089.26 CBY07551.1 - 6.6e-44 150.3 0.9 7.5e-44 150.2 0.9 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 CBY07551.1 - 0.029 13.9 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 TNV_CP PF03898.13 CBY07551.1 - 0.047 13.0 0.1 0.072 12.4 0.1 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein LpoB PF13036.6 CBY07551.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB DUF3042 PF11240.8 CBY07552.1 - 0.036 14.1 1.0 0.071 13.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF3149 PF11346.8 CBY07552.1 - 0.11 12.2 0.4 0.19 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Gp_dh_C PF02800.20 CBY07553.1 - 1.8e-59 199.8 0.5 2.6e-59 199.3 0.5 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBY07553.1 - 1.2e-33 115.4 0.0 3.4e-33 114.0 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBY07553.1 - 0.0016 18.5 3.0 0.025 14.7 0.3 3.3 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 CBY07553.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT_4 PF13291.6 CBY07553.1 - 0.11 13.1 0.1 0.34 11.5 0.0 1.9 2 0 0 2 2 2 0 ACT domain ITI_HC_C PF06668.12 CBY07554.1 - 9.3e-09 35.2 0.0 1.5e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus FeoB_associated PF12669.7 CBY07555.1 - 0.0086 16.5 3.2 0.013 15.9 3.2 1.2 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein ARF7EP_C PF14949.6 CBY07555.1 - 0.012 16.3 3.8 0.016 15.8 3.8 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Glycolytic PF00274.19 CBY07556.1 - 1.8e-07 30.2 0.0 1.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.19 CBY07557.1 - 7.2e-96 320.9 0.0 8.1e-96 320.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I CUB PF00431.20 CBY07559.1 - 2.1e-16 60.3 0.5 3.5e-13 49.9 0.0 2.9 3 0 0 3 3 3 2 CUB domain CUB PF00431.20 CBY07560.1 - 1.8e-26 92.6 6.1 9.7e-14 51.6 0.1 4.2 4 0 0 4 4 4 3 CUB domain DUF2724 PF10893.8 CBY07561.1 - 0.04 13.8 0.3 0.059 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Peptidase_C47 PF05543.13 CBY07561.1 - 0.095 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Staphopain peptidase C47 Meth_synt_2 PF01717.18 CBY07562.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain CENP-F_leu_zip PF10473.9 CBY07563.1 - 0.54 10.3 12.7 0.94 9.5 12.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 CBY07563.1 - 1.3 8.2 5.7 1.8 7.7 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Integrin_alpha2 PF08441.12 CBY07565.1 - 1.6e-49 169.1 1.7 5.3e-49 167.4 1.7 1.8 1 1 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CBY07565.1 - 2e-13 50.2 25.9 9.1e-08 32.1 7.1 5.2 5 0 0 5 5 5 3 FG-GAP repeat VCBS PF13517.6 CBY07565.1 - 2.8e-10 40.7 5.4 0.00024 21.6 0.3 3.9 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF11 PF01345.18 CBY07565.1 - 0.12 12.6 0.1 0.46 10.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF11 FG-GAP_2 PF14312.6 CBY07565.1 - 0.39 11.0 15.5 0.61 10.4 0.7 4.4 4 0 0 4 4 4 0 FG-GAP repeat Connexin PF00029.19 CBY07566.1 - 9.1e-35 120.5 3.5 1.2e-34 120.1 3.5 1.1 1 0 0 1 1 1 1 Connexin Cyc-maltodext_C PF10438.9 CBY07566.1 - 0.095 12.8 0.3 0.24 11.5 0.3 1.7 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Choline_kinase PF01633.20 CBY07567.1 - 4e-06 26.6 0.1 6.3e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CBY07567.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 CBY07567.1 - 0.021 13.7 0.1 0.03 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF2252 PF10009.9 CBY07567.1 - 0.063 12.3 0.1 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Ctr PF04145.15 CBY07568.1 - 3.1e-19 70.0 14.7 1.7e-11 45.0 6.3 2.4 2 1 1 3 3 3 2 Ctr copper transporter family C2 PF00168.30 CBY07569.1 - 4.5e-48 161.8 0.2 3.7e-23 81.8 0.1 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CBY07569.1 - 0.0041 16.7 0.0 0.014 15.0 0.0 1.9 1 0 0 1 1 1 1 CEP76 C2 domain DUF3137 PF11335.8 CBY07569.1 - 0.014 15.3 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) DUF3367 PF11847.8 CBY07570.1 - 0.21 9.4 1.5 0.29 9.0 1.5 1.2 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase PSK_trans_fac PF07704.11 CBY07570.1 - 0.6 10.9 4.5 0.39 11.5 0.6 2.7 3 1 1 4 4 4 0 Rv0623-like transcription factor ATP-synt_I PF03899.15 CBY07572.1 - 0.054 13.9 0.6 0.077 13.4 0.6 1.1 1 0 0 1 1 1 0 ATP synthase I chain zf-C2H2_assoc2 PF16624.5 CBY07573.1 - 1.3 10.1 0.0 1.3 10.1 0.0 2.6 3 1 0 3 3 3 0 Unstructured region upstream of a zinc-finger LRR_8 PF13855.6 CBY07574.1 - 7.5e-50 166.5 131.2 9.1e-09 35.0 2.4 10.8 2 2 13 15 15 15 15 Leucine rich repeat LRR_4 PF12799.7 CBY07574.1 - 5.5e-45 150.6 81.2 8.1e-07 29.3 3.4 12.8 6 2 7 14 14 14 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY07574.1 - 5.1e-14 52.2 35.4 0.00028 20.4 0.6 6.9 2 1 5 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.33 CBY07574.1 - 3.3e-11 42.1 62.9 0.23 12.2 0.0 18.4 15 4 2 17 17 17 5 Leucine Rich Repeat LRR_6 PF13516.6 CBY07574.1 - 2.6e-07 30.2 53.3 1.5 9.1 0.3 16.3 19 0 0 19 19 19 5 Leucine Rich repeat HigB_toxin PF09907.9 CBY07574.1 - 0.085 13.1 0.2 15 5.9 0.0 3.6 2 1 0 3 3 3 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system EF-hand_7 PF13499.6 CBY07575.1 - 7.2e-13 48.8 5.2 3.3e-09 37.1 0.9 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY07575.1 - 1.5e-09 36.7 1.2 0.00078 18.8 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY07575.1 - 1.1e-08 34.3 1.7 0.0084 16.0 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY07575.1 - 1.7e-06 27.3 2.6 0.019 14.4 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 CBY07575.1 - 0.0067 16.3 0.9 2.9 7.8 0.1 2.6 2 0 0 2 2 2 2 EF hand DUF4688 PF15752.5 CBY07575.1 - 0.37 10.0 3.5 0.62 9.2 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) Trypsin PF00089.26 CBY07576.1 - 2.1e-49 168.3 0.7 3.4e-49 167.6 0.7 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY07576.1 - 1.5e-06 29.2 0.0 3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ammonium_transp PF00909.21 CBY07577.1 - 2.1e-58 197.9 17.2 2.4e-58 197.7 17.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HMGL-like PF00682.19 CBY07577.1 - 0.67 9.5 4.1 1.2 8.7 4.1 1.4 1 0 0 1 1 1 0 HMGL-like TssO PF17561.2 CBY07578.1 - 0.056 13.6 1.5 0.056 13.6 1.5 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssO La PF05383.17 CBY07579.1 - 4.2e-14 52.3 0.1 1.1e-13 51.1 0.1 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY07579.1 - 0.083 12.7 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.6 CBY07580.1 - 1.4e-05 25.1 5.1 1.4e-05 25.1 5.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY07580.1 - 6.3e-05 23.2 9.0 6.3e-05 23.2 9.0 3.0 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY07580.1 - 0.00091 19.1 9.8 0.00091 19.1 9.8 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY07580.1 - 0.004 17.1 11.0 0.004 17.1 11.0 3.0 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY07580.1 - 0.0078 16.0 16.7 0.0083 16.0 11.4 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 CBY07580.1 - 0.0089 15.9 5.7 0.0089 15.9 5.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY07580.1 - 0.015 15.2 10.7 0.015 15.2 10.7 3.4 3 2 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY07580.1 - 0.031 14.1 13.2 0.28 11.0 7.1 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY07580.1 - 0.21 11.5 19.1 0.26 11.2 5.6 3.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Golgin_A5 PF09787.9 CBY07580.1 - 0.43 10.0 15.9 0.69 9.3 15.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 YojJ PF10372.9 CBY07580.1 - 0.59 10.3 4.0 1.4 9.0 0.6 2.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus zf-C2H2_jaz PF12171.8 CBY07580.1 - 0.65 10.4 5.7 1.7 9.0 0.3 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C3HC4_4 PF15227.6 CBY07580.1 - 1.2 9.3 9.3 5.3 7.3 6.6 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Sulfatase_C PF14707.6 CBY07580.1 - 1.3 9.8 4.8 2.5 8.9 0.5 2.6 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Enkurin PF13864.6 CBY07580.1 - 1.7 9.1 12.7 0.15 12.5 5.2 2.6 1 1 2 3 3 3 0 Calmodulin-binding V_ATPase_I PF01496.19 CBY07580.1 - 5.3 4.8 8.2 7.4 4.4 8.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 CBY07580.1 - 6.9 7.0 12.7 37 4.7 12.7 2.1 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Trypsin PF00089.26 CBY07581.1 - 2.3e-28 99.6 0.0 2.3e-28 99.6 0.0 1.8 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 CBY07581.1 - 6e-06 26.6 0.0 1.7e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) UPAR_LY6_2 PF16975.5 CBY07581.1 - 0.0058 16.8 11.0 0.0058 16.8 11.0 1.7 2 0 0 2 2 2 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Trypsin_2 PF13365.6 CBY07581.1 - 0.1 13.5 0.0 0.24 12.3 0.0 1.6 2 0 0 2 2 2 0 Trypsin-like peptidase domain DHR-2 PF06920.13 CBY07583.1 - 2.3e-39 135.4 0.1 3.8e-39 134.7 0.1 1.3 1 0 0 1 1 1 1 Dock homology region 2 ParcG PF10274.9 CBY07583.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Parkin co-regulated protein gerPA PF10676.9 CBY07585.1 - 0.041 14.1 3.1 4.1 7.7 0.3 2.5 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF DUF1657 PF07870.11 CBY07585.1 - 1.9 8.4 6.2 0.22 11.5 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) DUF1189 PF06691.11 CBY07586.1 - 0.13 11.8 11.1 0.19 11.3 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) DUF3573 PF12097.8 CBY07586.1 - 5.4 5.7 7.2 4.9 5.9 6.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) TOC159_MAD PF11886.8 CBY07587.1 - 0.007 15.3 0.0 0.008 15.1 0.0 1.0 1 0 0 1 1 1 1 Translocase of chloroplast 159/132, membrane anchor domain TSP_1 PF00090.19 CBY07588.1 - 3.1e-07 30.5 7.1 3.1e-07 30.5 7.1 1.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain Csm4_C PF17953.1 CBY07589.1 - 0.0027 17.5 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 CRISPR Csm4 C-terminal domain MutS_IV PF05190.18 CBY07590.1 - 0.017 15.4 0.7 0.063 13.6 0.2 2.1 2 0 0 2 2 2 0 MutS family domain IV Peptidase_M20 PF01546.28 CBY07591.1 - 4.1e-33 114.8 0.0 6.4e-33 114.2 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBY07591.1 - 3.7e-10 39.7 0.0 6.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 CBY07592.1 - 1.6e-32 112.9 0.0 2.6e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBY07592.1 - 2.6e-14 53.1 0.0 4.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain MA-Mit PF09245.10 CBY07593.1 - 0.052 13.0 1.5 0.082 12.4 1.0 1.4 1 1 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen DUF4743 PF15916.5 CBY07594.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) ACPS PF01648.20 CBY07594.1 - 0.048 13.8 0.0 0.068 13.3 0.0 1.3 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily DUF4743 PF15916.5 CBY07595.1 - 1.7e-06 28.0 0.0 4.1e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 CBY07595.1 - 7.1e-05 22.9 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.28 CBY07596.1 - 1.5e-17 64.8 0.6 2.2e-17 64.3 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Phage_integrase PF00589.22 CBY07596.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family Astacin PF01400.24 CBY07597.1 - 1.7e-23 83.3 0.0 1e-21 77.4 0.0 2.2 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Kunitz_BPTI PF00014.23 CBY07598.1 - 4.5e-22 78.0 5.9 5.3e-22 77.8 5.9 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Fungus-induced PF10917.8 CBY07598.1 - 0.1 12.9 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Fungus-induced protein CTP_transf_like PF01467.26 CBY07599.1 - 3e-23 82.6 0.4 2.2e-22 79.8 0.1 2.4 2 1 0 2 2 2 1 Cytidylyltransferase-like DDE_Tnp_1_4 PF13701.6 CBY07599.1 - 0.16 10.2 0.1 0.22 9.7 0.1 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 Peptidase_M10 PF00413.24 CBY07600.1 - 1.7e-48 164.5 0.0 5.3e-48 162.8 0.0 1.9 1 1 0 1 1 1 1 Matrixin fn2 PF00040.19 CBY07600.1 - 1.1e-41 140.9 39.8 4.9e-18 65.1 5.3 4.2 4 0 0 4 4 4 3 Fibronectin type II domain Hemopexin PF00045.19 CBY07600.1 - 1.4e-16 60.1 2.8 2.4e-09 37.0 0.0 3.0 3 0 0 3 3 3 2 Hemopexin PG_binding_1 PF01471.18 CBY07600.1 - 0.0007 19.8 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M66 PF10462.9 CBY07600.1 - 0.011 14.7 0.3 0.021 13.8 0.3 1.4 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 CBY07600.1 - 0.024 13.3 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M54 PF07998.11 CBY07600.1 - 0.025 14.6 0.1 0.046 13.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 MIEAP PF16026.5 CBY07601.1 - 1.4e-48 165.8 0.1 1.4e-48 165.8 0.1 2.6 3 0 0 3 3 3 1 Mitochondria-eating protein Arm_APC_u3 PF16629.5 CBY07601.1 - 0.017 14.7 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Armadillo-associated region on APC DUF812 PF05667.11 CBY07601.1 - 0.089 11.7 15.1 0.24 10.3 15.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 CBY07601.1 - 0.49 9.7 7.2 1 8.7 7.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Herpes_LP PF03363.13 CBY07601.1 - 0.71 9.6 4.2 4.6 7.0 2.1 2.5 2 0 0 2 2 2 0 Herpesvirus leader protein Prominin PF05478.11 CBY07601.1 - 1.1 7.2 5.6 1.7 6.5 5.6 1.2 1 0 0 1 1 1 0 Prominin ATG16 PF08614.11 CBY07601.1 - 1.6 8.9 21.7 4.1 7.6 21.5 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Lipoprotein_20 PF13942.6 CBY07601.1 - 3.3 7.6 9.9 7.8 6.4 9.9 1.6 1 0 0 1 1 1 0 YfhG lipoprotein Exonuc_VII_L PF02601.15 CBY07601.1 - 5.7 6.4 11.5 24 4.4 11.7 1.9 2 1 0 2 2 2 0 Exonuclease VII, large subunit Lectin_C PF00059.21 CBY07602.1 - 6.8e-12 46.1 0.4 8.6e-12 45.8 0.4 1.1 1 0 0 1 1 1 1 Lectin C-type domain MtrB PF05440.12 CBY07604.1 - 0.23 11.9 0.1 0.76 10.2 0.0 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF1192 PF06698.11 CBY07604.1 - 1.8 8.7 6.1 3.8 7.7 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) C8 PF08742.11 CBY07605.1 - 0.00015 22.1 2.5 0.00029 21.2 2.5 1.6 1 0 0 1 1 1 1 C8 domain VWD PF00094.25 CBY07605.1 - 0.13 12.5 0.3 0.23 11.7 0.3 1.4 1 0 0 1 1 1 0 von Willebrand factor type D domain PAN_3 PF08277.12 CBY07607.1 - 0.00054 19.7 13.7 0.028 14.2 2.6 3.1 3 0 0 3 3 3 2 PAN-like domain PAN_1 PF00024.26 CBY07607.1 - 0.0018 18.2 14.3 0.06 13.3 4.3 3.0 3 0 0 3 3 3 2 PAN domain fn3 PF00041.21 CBY07608.1 - 2.9e-71 235.9 17.3 7.6e-15 55.0 0.1 10.6 10 0 0 10 10 10 10 Fibronectin type III domain LCCL PF03815.19 CBY07608.1 - 8.4e-20 70.7 1.2 4.3e-19 68.4 0.8 2.4 2 0 0 2 2 2 1 LCCL domain Pur_ac_phosph_N PF16656.5 CBY07608.1 - 1.7e-15 57.3 27.6 0.021 15.4 0.0 11.5 8 4 0 8 8 8 4 Purple acid Phosphatase, N-terminal domain DUF4992 PF16383.5 CBY07608.1 - 3.3e-15 56.1 13.5 5.2e-05 22.9 0.1 8.0 6 3 1 8 8 8 3 Domain of unknown function Interfer-bind PF09294.10 CBY07608.1 - 1.1e-09 38.6 0.0 7.7 6.9 0.0 7.8 9 0 0 9 9 7 1 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 CBY07608.1 - 1.1e-09 38.3 0.1 0.094 12.9 0.0 7.7 9 1 0 9 9 9 2 Fibronectin type III domain DUF2369 PF10179.9 CBY07608.1 - 1.3e-09 38.3 1.9 0.74 10.2 0.0 7.3 8 0 0 8 8 8 2 Uncharacterised conserved protein (DUF2369) Arylsulfotran_N PF17425.2 CBY07608.1 - 6.2e-05 22.9 2.7 25 5.0 0.0 6.2 6 1 1 7 7 7 0 Arylsulfotransferase Ig-like domain fn3_4 PF16794.5 CBY07608.1 - 0.0046 16.8 0.5 5.9 6.9 0.0 5.6 5 1 0 5 5 5 1 Fibronectin-III type domain Rxt3 PF08642.10 CBY07608.1 - 0.0067 17.2 0.4 0.47 11.2 0.2 2.6 1 1 1 2 2 2 1 Histone deacetylation protein Rxt3 Big_4 PF07532.11 CBY07608.1 - 0.021 14.6 1.9 7.3 6.4 0.2 4.8 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 4) MR_MLE_N PF02746.16 CBY07608.1 - 0.11 12.7 0.6 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1410 PF07198.11 CBY07608.1 - 0.31 11.6 5.1 1.1e+02 3.4 0.0 4.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1410) SDF PF00375.18 CBY07609.1 - 2.9e-85 286.7 19.1 3.4e-85 286.4 19.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Na_Ca_ex PF01699.24 CBY07609.1 - 0.0032 17.4 8.4 0.0032 17.4 8.4 2.3 1 1 1 2 2 2 1 Sodium/calcium exchanger protein TerB_C PF15615.6 CBY07610.1 - 0.073 13.4 0.6 0.11 12.8 0.6 1.3 1 0 0 1 1 1 0 TerB-C domain Sod_Fe_N PF00081.22 CBY07611.1 - 4.9e-33 113.4 2.0 3.9e-32 110.5 0.4 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CBY07611.1 - 1.7e-09 37.7 0.2 6.4e-09 35.9 0.1 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain TRAM_LAG1_CLN8 PF03798.16 CBY07612.1 - 5.3e-16 59.0 10.1 5.9e-16 58.8 10.1 1.0 1 0 0 1 1 1 1 TLC domain DUF4956 PF16316.5 CBY07612.1 - 0.26 11.0 2.6 0.39 10.4 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) Glyco_hydro_9 PF00759.19 CBY07613.1 - 1.9e-231 768.7 13.2 2.6e-127 425.7 3.7 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 Homeodomain PF00046.29 CBY07614.1 - 2.4e-21 75.3 4.8 5e-21 74.3 4.8 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY07614.1 - 5e-05 23.1 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CBY07614.1 - 0.021 14.3 0.3 0.043 13.3 0.3 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez PepSY_2 PF13670.6 CBY07615.1 - 0.12 12.4 0.2 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Gp_dh_C PF02800.20 CBY07616.1 - 0.043 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain CUB PF00431.20 CBY07617.1 - 7.4e-11 42.4 0.0 1.7e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 CUB domain Carb_anhydrase PF00194.21 CBY07618.1 - 1.9e-78 263.6 0.1 2.2e-78 263.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Acyl-CoA_dh_1 PF00441.24 CBY07619.1 - 2.4e-37 128.4 1.8 3.5e-37 127.9 1.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY07619.1 - 5.2e-28 98.0 0.0 3.5e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY07619.1 - 1.8e-21 76.1 0.0 3.5e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY07619.1 - 3.2e-08 33.9 0.0 4.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 3Beta_HSD PF01073.19 CBY07620.1 - 3.9e-11 42.5 0.0 6.3e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CBY07620.1 - 0.00013 21.5 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBY07620.1 - 0.041 13.3 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CBY07621.1 - 3.1e-38 131.4 0.0 3.8e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CBY07621.1 - 3.6e-20 72.5 0.0 4.4e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CBY07621.1 - 1.8e-13 50.3 0.0 3.2e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CBY07621.1 - 1.4e-10 41.4 0.0 1.8e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CBY07621.1 - 5.5e-09 35.5 0.0 6.8e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CBY07621.1 - 9e-06 25.3 0.2 2e-05 24.2 0.2 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CBY07621.1 - 7.6e-05 22.0 0.8 0.0014 17.9 0.3 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CBY07621.1 - 0.00035 20.2 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 CBY07621.1 - 0.015 14.8 0.0 0.031 13.7 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Arm PF00514.23 CBY07622.1 - 6.2e-18 64.2 14.2 4.2e-09 36.1 0.0 10.0 12 0 0 12 12 12 3 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 CBY07622.1 - 0.00022 20.7 0.2 0.044 13.2 0.0 3.1 3 0 0 3 3 3 1 Family of unknown function (DUF5578) Arm_2 PF04826.13 CBY07622.1 - 0.0025 17.3 2.0 0.019 14.5 0.8 2.6 3 0 0 3 3 3 1 Armadillo-like V-ATPase_H_C PF11698.8 CBY07622.1 - 0.005 16.9 3.1 8.2 6.6 0.0 4.7 5 0 0 5 5 5 1 V-ATPase subunit H CTNNBL PF08216.11 CBY07622.1 - 0.013 15.7 0.6 1.6 9.0 0.1 3.6 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear TetR_C_35 PF18556.1 CBY07622.1 - 0.028 14.6 0.9 5.5 7.2 0.1 3.0 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain Ric8 PF10165.9 CBY07622.1 - 0.1 11.6 0.5 1.4 7.8 0.0 2.7 2 1 1 3 3 3 0 Guanine nucleotide exchange factor synembryn HEAT PF02985.22 CBY07622.1 - 0.31 11.4 1.8 1.3e+02 3.2 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat RhoGEF PF00621.20 CBY07624.1 - 4.5e-32 111.7 0.4 5.7e-32 111.4 0.4 1.1 1 0 0 1 1 1 1 RhoGEF domain PDZ PF00595.24 CBY07625.1 - 5e-12 46.0 0.4 3.6e-11 43.3 0.1 2.3 2 0 0 2 2 2 1 PDZ domain DIL PF01843.19 CBY07625.1 - 1.1e-10 41.7 0.0 2.6e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 DIL domain PDZ_6 PF17820.1 CBY07625.1 - 3e-07 30.2 0.0 1.4e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CBY07625.1 - 1.8e-05 25.0 0.1 4.3e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DUF2935 PF11155.8 CBY07625.1 - 0.057 13.7 1.8 0.25 11.7 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Trypsin PF00089.26 CBY07626.1 - 3.4e-53 180.7 0.0 4.9e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY07626.1 - 0.0012 19.2 0.0 0.002 18.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY07626.1 - 0.025 15.5 0.0 0.045 14.6 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain DUF316 PF03761.15 CBY07626.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 DUF1205 PF06722.12 CBY07626.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) Glyco_hydro_47 PF01532.20 CBY07628.1 - 6.2e-125 417.7 0.4 1.5e-124 416.4 0.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Thioredoxin PF00085.20 CBY07628.1 - 3.6e-05 23.7 0.1 8.6e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin DUF2570 PF10828.8 CBY07628.1 - 0.0088 15.8 0.2 0.019 14.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) Thioredoxin_2 PF13098.6 CBY07628.1 - 0.024 15.1 1.0 0.23 11.9 1.0 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain P5CR_dimer PF14748.6 CBY07628.1 - 0.037 14.3 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation NB-ARC PF00931.22 CBY07629.1 - 0.039 13.2 0.3 0.079 12.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain CDH1_2_SANT_HL1 PF18375.1 CBY07629.1 - 0.17 12.6 1.8 0.33 11.6 0.1 2.2 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 SNF PF00209.18 CBY07630.1 - 3.5e-34 118.4 6.9 4e-34 118.2 6.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ctr PF04145.15 CBY07630.1 - 0.046 14.3 0.0 0.084 13.5 0.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family COX4 PF02936.14 CBY07630.1 - 0.11 12.5 0.1 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV RRM_8 PF11835.8 CBY07630.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 RRM-like domain COesterase PF00135.28 CBY07631.1 - 1.4e-63 215.5 0.0 2.2e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY07631.1 - 0.00021 21.2 0.0 0.0005 20.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Beta_elim_lyase PF01212.21 CBY07632.1 - 2.2e-87 293.1 0.0 2.6e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CBY07632.1 - 3.6e-08 33.0 0.0 4.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CBY07632.1 - 3.7e-06 26.5 0.0 8.9e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CBY07632.1 - 5.2e-06 25.6 0.0 0.00011 21.2 0.0 2.0 1 1 1 2 2 2 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 CBY07632.1 - 0.0023 16.7 0.0 0.0054 15.5 0.0 1.6 1 1 1 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Kunitz_BPTI PF00014.23 CBY07633.1 - 4.6e-16 58.8 1.5 5.1e-16 58.6 1.5 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Sugar_tr PF00083.24 CBY07634.1 - 9.8e-24 84.0 0.7 1.3e-23 83.6 0.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY07634.1 - 7.5e-11 41.5 3.1 1.2e-10 40.8 3.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CBY07634.1 - 6.9e-06 25.6 1.2 1e-05 25.0 1.2 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Galactosyl_T PF01762.21 CBY07635.1 - 7.3e-36 123.8 0.5 1.5e-35 122.8 0.3 1.6 2 0 0 2 2 2 1 Galactosyltransferase DUF2205 PF10224.9 CBY07635.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 Short coiled-coil protein ApoLp-III PF07464.11 CBY07636.1 - 0.002 18.3 3.1 0.002 18.3 3.1 1.7 2 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) RE_HindIII PF09518.10 CBY07636.1 - 0.0041 16.4 3.0 0.16 11.2 1.8 2.0 1 1 1 2 2 2 1 HindIII restriction endonuclease Vps53_N PF04100.12 CBY07636.1 - 0.0051 15.8 2.3 0.0071 15.4 2.3 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal ISG65-75 PF11727.8 CBY07636.1 - 0.0079 15.5 2.0 0.0079 15.5 2.0 1.5 2 0 0 2 2 2 1 Invariant surface glycoprotein YfdX PF10938.8 CBY07636.1 - 0.0082 16.1 0.5 0.077 12.9 0.1 2.2 2 0 0 2 2 2 1 YfdX protein YscO-like PF16789.5 CBY07636.1 - 0.016 15.2 4.1 0.016 15.2 4.1 1.6 2 0 0 2 2 2 0 YscO-like protein MCPsignal PF00015.21 CBY07636.1 - 0.019 14.8 2.0 0.032 14.0 2.0 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain REC1 PF18501.1 CBY07636.1 - 0.028 14.3 0.8 0.028 14.3 0.8 1.8 2 0 0 2 2 2 0 Alpha helical recognition lobe domain Mis14 PF08641.12 CBY07636.1 - 0.03 14.6 6.2 0.2 12.0 3.4 2.2 1 1 0 2 2 2 0 Kinetochore protein Mis14 like 5_nucleotid PF05761.14 CBY07636.1 - 0.078 11.9 2.0 0.1 11.5 2.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF1043 PF06295.12 CBY07636.1 - 0.082 12.9 3.4 0.98 9.4 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) ECH_2 PF16113.5 CBY07636.1 - 0.19 11.2 2.4 0.3 10.6 1.9 1.5 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ZnuA PF01297.17 CBY07636.1 - 0.19 11.1 2.3 0.26 10.7 2.2 1.3 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF948 PF06103.11 CBY07636.1 - 0.37 11.1 3.7 1.4 9.2 0.2 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 CBY07636.1 - 0.48 11.2 5.5 1 10.1 3.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Phasin PF05597.11 CBY07636.1 - 0.71 9.9 6.2 0.66 10.0 2.5 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.13 CBY07636.1 - 2.9 8.6 6.2 10 6.8 3.3 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) APG6_N PF17675.1 CBY07636.1 - 3.3 8.2 10.3 11 6.6 10.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region CAP_C PF08603.11 CBY07637.1 - 1.3e-39 135.3 8.0 1.3e-39 135.3 8.0 1.8 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 CBY07637.1 - 9.8e-05 22.0 1.1 0.00023 20.8 0.6 2.0 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 CBY07637.1 - 0.069 12.9 2.9 0.16 11.7 2.9 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor C Siah-Interact_N PF09032.11 CBY07637.1 - 1 9.7 6.3 0.53 10.6 2.1 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal OppC_N PF12911.7 CBY07638.1 - 1.2 9.2 12.5 2 8.5 1.4 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C ATP1G1_PLM_MAT8 PF02038.16 CBY07638.1 - 1.9 8.0 6.0 4.2 6.9 0.2 2.9 1 1 0 2 2 2 0 ATP1G1/PLM/MAT8 family Zona_pellucida PF00100.23 CBY07640.1 - 2.6e-20 73.3 7.9 3e-20 73.1 7.9 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Glyco_hydro_81 PF03639.13 CBY07640.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 N-terminal domain TFIIE_alpha PF02002.17 CBY07641.1 - 3.1e-17 62.4 1.2 6.3e-17 61.4 1.2 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 CBY07641.1 - 4.2e-08 33.4 9.0 1.3e-07 31.9 9.0 2.0 1 1 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 CBY07641.1 - 5.3e-06 25.9 1.7 1.5e-05 24.4 1.7 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.13 CBY07641.1 - 0.082 13.0 1.0 0.16 12.0 1.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like RabGAP-TBC PF00566.18 CBY07642.1 - 9e-34 117.0 3.9 5.2e-31 108.0 0.8 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain UNC-93 PF05978.16 CBY07644.1 - 8e-21 74.4 8.4 1.9e-20 73.2 6.6 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 UB2H PF14814.6 CBY07646.1 - 0.078 13.0 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain GDPD PF03009.17 CBY07647.1 - 3.5e-08 33.5 0.0 4.7e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 CBY07648.1 - 2.3e-29 102.9 0.0 2.6e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family STAS PF01740.21 CBY07649.1 - 0.16 11.6 0.0 3.8 7.2 0.0 2.5 3 0 0 3 3 3 0 STAS domain adh_short_C2 PF13561.6 CBY07651.1 - 1.8e-57 194.6 1.8 2.2e-57 194.3 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY07651.1 - 2.8e-49 167.2 0.2 3.5e-49 166.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY07651.1 - 1.7e-13 50.9 0.3 2.7e-13 50.2 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY07651.1 - 6.9e-06 25.7 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBY07651.1 - 7e-05 22.8 0.6 0.00018 21.5 0.6 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CBY07651.1 - 0.0026 17.2 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 CBY07651.1 - 0.0068 16.7 0.1 0.0068 16.7 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 CBY07651.1 - 0.01 15.2 0.1 0.045 13.1 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 CBY07651.1 - 0.083 12.8 0.1 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.26 CBY07652.1 - 2.6e-22 79.4 0.0 4.8e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CBY07652.1 - 2.9e-07 30.0 0.1 5.8e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY07652.1 - 0.023 14.2 0.0 0.24 10.8 0.0 2.1 1 1 0 1 1 1 0 Glycosyltransferase like family 2 SVS_QK PF10578.9 CBY07652.1 - 0.15 12.7 0.4 0.72 10.6 0.4 2.2 1 0 0 1 1 1 0 Seminal vesicle protein repeat MctB PF11382.8 CBY07653.1 - 0.049 13.3 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB EF-hand_1 PF00036.32 CBY07654.1 - 1.9e-14 52.0 5.9 1.3e-05 24.4 0.2 3.3 2 1 1 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY07654.1 - 1.4e-12 46.4 3.1 2.2e-05 24.0 0.1 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBY07654.1 - 5e-12 45.5 4.8 3.5e-05 23.6 0.1 3.3 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 CBY07654.1 - 2.6e-11 43.8 2.9 8.4e-11 42.2 1.0 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY07654.1 - 3e-11 42.3 4.6 7.4e-05 22.1 0.2 2.8 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 CBY07654.1 - 0.0067 16.7 0.4 0.016 15.5 0.4 1.7 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region PRD PF00874.20 CBY07654.1 - 0.026 14.8 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 PRD domain DUF5508 PF17621.2 CBY07654.1 - 0.029 13.5 0.3 0.047 12.8 0.3 1.3 1 1 1 2 2 2 0 Family of unknown function (DUF5508) RecG_N PF17190.4 CBY07654.1 - 0.039 14.7 1.6 0.064 14.0 0.3 1.9 2 0 0 2 2 2 0 RecG N-terminal helical domain Xylo_C PF12529.8 CBY07654.1 - 0.047 13.3 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Xylosyltransferase C terminal adh_short PF00106.25 CBY07657.1 - 1.9e-26 92.7 0.1 3.1e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY07657.1 - 1e-22 80.8 0.2 1.4e-22 80.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY07657.1 - 1.4e-06 28.4 0.1 2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 CBY07657.1 - 0.028 14.6 0.1 0.047 13.9 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 CBY07657.1 - 0.053 12.7 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-RING_2 PF13639.6 CBY07658.1 - 4.5e-07 30.1 5.9 1.1e-06 28.8 5.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBY07658.1 - 1e-06 28.9 5.5 1.8e-06 28.1 5.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBY07658.1 - 3e-06 27.0 3.2 7e-06 25.8 3.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY07658.1 - 1.1e-05 25.4 4.0 2e-05 24.6 4.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CBY07658.1 - 0.00011 22.0 1.9 0.00011 22.0 1.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY07658.1 - 0.00012 21.9 5.2 0.00028 20.8 5.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY07658.1 - 0.0037 17.3 7.7 0.011 15.8 2.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY07658.1 - 0.021 14.7 4.3 0.021 14.7 4.3 1.8 2 1 0 2 2 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY07658.1 - 0.039 13.8 4.9 0.17 11.8 4.9 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fibrillin_U_N PF18193.1 CBY07658.1 - 0.09 12.9 1.2 0.19 11.8 1.2 1.5 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain zf-C3HC4_4 PF15227.6 CBY07658.1 - 0.093 12.9 1.0 0.26 11.5 1.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ArAE_2_N PF10337.9 CBY07658.1 - 0.11 11.5 4.9 0.36 9.8 0.3 2.2 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal FANCL_C PF11793.8 CBY07658.1 - 0.16 12.1 5.2 2.3 8.5 5.2 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 CBY07658.1 - 0.51 10.1 8.9 0.18 11.6 5.0 2.3 2 1 0 2 2 2 0 RING-like zinc finger zf-UDP PF14569.6 CBY07658.1 - 1 9.6 7.1 2.6 8.2 6.1 2.1 1 1 1 2 2 2 0 Zinc-binding RING-finger DUF3796 PF12676.7 CBY07658.1 - 4.7 7.7 8.6 2.2 8.7 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) Ank_2 PF12796.7 CBY07659.1 - 1.8e-21 76.5 0.9 2.6e-09 37.5 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY07659.1 - 1.2e-17 64.1 0.0 7.4e-05 23.2 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY07659.1 - 2.6e-09 36.6 0.0 0.24 12.1 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBY07659.1 - 1.4e-07 31.6 0.1 0.004 17.4 0.2 3.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY07659.1 - 8.6e-05 22.8 0.1 0.96 10.0 0.1 4.7 5 1 0 5 5 5 1 Ankyrin repeat MAGE_N PF12440.8 CBY07660.1 - 0.032 14.9 4.8 0.05 14.3 4.8 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF4897 PF16238.5 CBY07660.1 - 0.061 13.2 0.3 0.094 12.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) Kinesin PF00225.23 CBY07661.1 - 3.8e-101 338.3 0.4 6.2e-101 337.6 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY07661.1 - 3.4e-21 75.7 0.5 1.2e-20 73.9 0.2 2.1 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 CBY07661.1 - 1.9e-06 28.2 1.8 2.5e-06 27.8 0.2 2.1 2 0 0 2 2 2 1 Kinesin-associated FHA PF00498.26 CBY07661.1 - 3.4e-06 27.3 0.0 1.2e-05 25.5 0.0 2.1 1 0 0 1 1 1 1 FHA domain KIF1B PF12423.8 CBY07661.1 - 0.00033 21.0 2.2 0.00038 20.8 0.5 2.1 2 0 0 2 2 2 1 Kinesin protein 1B UPF0242 PF06785.11 CBY07661.1 - 0.011 15.8 0.7 0.023 14.8 0.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Yop-YscD_cpl PF16697.5 CBY07661.1 - 0.011 16.0 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain SKA2 PF16740.5 CBY07661.1 - 0.058 13.2 0.3 0.19 11.5 0.3 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF2570 PF10828.8 CBY07661.1 - 0.14 12.0 0.7 0.37 10.6 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) CUB PF00431.20 CBY07664.1 - 4.6e-13 49.5 0.5 1.1e-11 45.0 0.0 2.2 1 1 1 2 2 2 2 CUB domain DUF905 PF06006.12 CBY07665.1 - 0.029 14.4 0.0 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) Acyl-CoA_dh_1 PF00441.24 CBY07666.1 - 2.1e-38 131.9 2.8 3.4e-38 131.2 2.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY07666.1 - 3.9e-27 95.1 0.0 1.2e-26 93.5 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY07666.1 - 1.2e-23 83.2 0.0 2.5e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY07666.1 - 4.7e-15 56.0 0.3 6.6e-15 55.6 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Kelch_6 PF13964.6 CBY07667.1 - 3.8e-06 27.0 0.3 0.061 13.6 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY07667.1 - 0.00033 20.6 1.6 0.0012 18.8 0.2 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY07667.1 - 0.014 15.4 0.3 0.64 10.1 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CBY07667.1 - 0.026 14.1 0.4 0.099 12.2 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Ets PF00178.22 CBY07668.1 - 1.2e-36 125.0 1.9 2e-36 124.3 1.9 1.3 1 0 0 1 1 1 1 Ets-domain RNA_pol_Rpc34 PF05158.12 CBY07668.1 - 0.089 12.2 2.7 0.094 12.1 1.9 1.5 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit UPAR_LY6_2 PF16975.5 CBY07670.1 - 7.7e-42 141.8 14.3 1e-41 141.5 14.3 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 DUF5321 PF17254.2 CBY07671.1 - 0.028 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5321) HGTP_anticodon PF03129.20 CBY07672.1 - 3.4e-17 62.4 0.0 1.2e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.20 CBY07672.1 - 1.3e-10 41.2 7.2 3.1e-10 40.0 7.2 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 CBY07672.1 - 8.8e-10 38.8 0.0 1.1e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF2996 PF11210.8 CBY07672.1 - 0.091 13.2 0.6 0.36 11.3 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) adh_short PF00106.25 CBY07673.1 - 4.4e-48 163.3 1.8 5.1e-48 163.1 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY07673.1 - 4e-35 121.5 0.8 4.9e-35 121.2 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY07673.1 - 1.7e-09 37.8 0.8 2.7e-09 37.2 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY07673.1 - 0.034 13.6 0.2 0.053 13.0 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sulfotransfer_1 PF00685.27 CBY07674.1 - 2.5e-15 56.7 0.0 8.4e-15 55.0 0.0 2.0 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY07674.1 - 8.6e-07 29.6 0.1 0.093 13.1 0.1 3.7 2 1 0 2 2 2 2 Sulfotransferase family DUF1103 PF06513.11 CBY07674.1 - 0.064 12.9 0.6 0.1 12.2 0.6 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) F-box-like PF12937.7 CBY07675.1 - 2e-08 34.0 0.1 3.5e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY07675.1 - 3.2e-05 23.7 4.6 0.00046 20.0 4.6 2.1 1 1 0 1 1 1 1 F-box domain KIP1 PF07765.12 CBY07677.1 - 8e-05 22.7 13.6 0.0075 16.4 0.4 2.8 1 1 2 3 3 3 2 KIP1-like protein Lectin_N PF03954.14 CBY07677.1 - 0.00084 19.1 0.7 0.00084 19.1 0.7 2.6 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain EzrA PF06160.12 CBY07677.1 - 0.005 15.1 20.5 0.0073 14.5 20.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA MbeD_MobD PF04899.12 CBY07677.1 - 0.0087 16.2 6.2 0.61 10.2 0.1 2.4 1 1 0 2 2 2 2 MbeD/MobD like PMI_typeI PF01238.21 CBY07677.1 - 0.012 14.8 6.7 0.014 14.6 6.7 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I DUF3584 PF12128.8 CBY07677.1 - 0.019 12.5 13.7 0.022 12.3 13.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HsbA PF12296.8 CBY07677.1 - 0.035 14.5 0.4 0.35 11.3 0.2 2.0 2 0 0 2 2 2 0 Hydrophobic surface binding protein A YqaH PF17448.2 CBY07677.1 - 0.041 14.2 0.7 0.075 13.4 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized YqaH-like Fib_alpha PF08702.10 CBY07677.1 - 0.11 12.7 17.4 0.23 11.6 12.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EDR1 PF14381.6 CBY07677.1 - 0.11 12.2 1.7 0.14 11.9 1.7 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 SKA1 PF07160.12 CBY07677.1 - 0.11 12.3 13.4 0.16 11.8 13.4 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF1664 PF07889.12 CBY07677.1 - 0.14 12.2 12.6 1.5 8.9 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF445 PF04286.12 CBY07677.1 - 0.15 11.9 8.3 0.16 11.7 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ESM4 PF15952.5 CBY07677.1 - 0.29 11.6 15.8 0.38 11.2 15.8 1.1 1 0 0 1 1 1 0 Enhancer of split M4 family Spectrin PF00435.21 CBY07677.1 - 0.29 11.6 13.8 1.1 9.7 1.1 2.2 1 1 1 2 2 2 0 Spectrin repeat Exonuc_VII_L PF02601.15 CBY07677.1 - 0.33 10.5 11.4 0.47 10.0 11.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 CBY07677.1 - 0.53 9.7 21.4 0.8 9.1 21.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 LMBR1 PF04791.16 CBY07677.1 - 0.77 8.6 12.6 0.91 8.4 12.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ATP-synt_B PF00430.18 CBY07677.1 - 0.84 9.7 8.9 1.2 9.3 8.9 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) OSCP PF00213.18 CBY07677.1 - 1.3 9.2 10.9 1.6 8.8 10.9 1.1 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit ApoO PF09769.9 CBY07677.1 - 1.3 9.0 6.5 7.8 6.5 0.6 2.5 1 1 2 3 3 3 0 Apolipoprotein O HAP1_N PF04849.13 CBY07677.1 - 1.4 8.1 24.6 5.5 6.1 24.6 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region NPV_P10 PF05531.12 CBY07677.1 - 1.7 9.2 8.1 9.9 6.7 0.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 CBY07677.1 - 1.9 8.7 24.2 3.8 7.7 4.2 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ACCA PF03255.14 CBY07677.1 - 2.2 8.2 15.7 2.6 7.9 7.0 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4988 PF16378.5 CBY07677.1 - 2.2 7.9 7.1 0.99 9.0 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF3087 PF11286.8 CBY07677.1 - 2.7 7.4 7.7 0.77 9.2 1.2 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF3087) Cnn_1N PF07989.11 CBY07677.1 - 2.8 8.2 22.1 9 6.5 4.3 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF948 PF06103.11 CBY07677.1 - 2.9 8.2 5.7 7.7 6.9 4.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LAGLIDADG_1 PF00961.19 CBY07677.1 - 3.6 8.6 8.4 2.1 9.3 5.3 1.9 1 1 1 2 2 2 0 LAGLIDADG endonuclease TMPIT PF07851.13 CBY07677.1 - 4.6 6.4 18.3 0.89 8.7 10.3 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF3450 PF11932.8 CBY07677.1 - 5.2 6.3 17.6 5.6 6.2 15.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ALMT PF11744.8 CBY07677.1 - 6.9 5.4 13.4 8.5 5.1 13.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter BST2 PF16716.5 CBY07677.1 - 8.2 7.1 17.3 0.23 12.1 3.6 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 AAA_12 PF13087.6 CBY07678.1 - 2.5e-45 154.5 1.0 2.5e-45 154.5 1.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBY07678.1 - 1.7e-19 70.7 16.6 8.8e-19 68.3 9.3 3.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBY07678.1 - 6e-08 33.1 0.0 7e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBY07678.1 - 4.5e-06 26.5 0.0 0.001 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBY07678.1 - 0.0037 16.7 0.0 0.008 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 CBY07678.1 - 0.0075 16.7 0.0 0.026 14.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY07678.1 - 0.014 15.7 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CBY07678.1 - 0.015 15.3 0.0 0.05 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY07678.1 - 0.029 14.8 0.0 0.078 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CBY07678.1 - 0.062 13.5 0.0 0.34 11.1 0.0 2.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CBY07678.1 - 0.078 12.4 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 CBY07678.1 - 0.13 12.3 0.0 0.13 12.3 0.0 3.3 3 1 0 4 4 4 0 Type III restriction enzyme, res subunit Eco57I PF07669.11 CBY07678.1 - 0.18 12.3 1.1 0.72 10.4 1.1 2.1 1 0 0 1 1 1 0 Eco57I restriction-modification methylase C1_2 PF03107.16 CBY07679.1 - 0.029 14.7 1.5 0.048 14.0 1.5 1.3 1 0 0 1 1 1 0 C1 domain DUF3878 PF12994.7 CBY07679.1 - 0.096 12.1 0.3 0.13 11.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) UB2H PF14814.6 CBY07679.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain VATC PF18716.1 CBY07679.1 - 0.12 12.3 4.1 0.23 11.3 4.1 1.5 1 0 0 1 1 1 0 Vms1-associating treble clef domain zinc_ribbon_2 PF13240.6 CBY07679.1 - 0.15 11.8 1.0 0.34 10.7 1.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-FCS PF06467.14 CBY07679.1 - 0.19 11.7 8.0 2.1 8.3 8.0 2.4 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif YyzF PF14116.6 CBY07679.1 - 0.19 11.8 2.1 0.23 11.5 0.6 1.9 2 0 0 2 2 2 0 YyzF-like protein YhfH PF14149.6 CBY07679.1 - 0.47 10.5 4.9 0.92 9.5 4.9 1.5 1 0 0 1 1 1 0 YhfH-like protein DUF1382 PF07131.11 CBY07679.1 - 0.97 9.5 3.9 19 5.4 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) p450 PF00067.22 CBY07680.1 - 4e-85 286.3 0.2 8.3e-85 285.3 0.2 1.5 1 1 0 1 1 1 1 Cytochrome P450 SLC3A2_N PF16028.5 CBY07681.1 - 3.7e-28 96.9 0.1 6.1e-28 96.2 0.1 1.3 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus GTP_EFTU PF00009.27 CBY07681.1 - 0.053 13.0 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain C5-epim_C PF06662.13 CBY07682.1 - 1e-54 184.9 0.0 1.6e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Zona_pellucida PF00100.23 CBY07683.1 - 1.1e-39 136.8 2.7 1.6e-39 136.3 2.7 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3439 PF11921.8 CBY07683.1 - 0.02 14.9 0.2 0.036 14.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2207 PF09972.9 CBY07684.1 - 0.00082 18.3 0.1 0.00096 18.0 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SLATT_5 PF18160.1 CBY07684.1 - 0.00097 18.5 0.9 0.0018 17.7 0.9 1.4 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 Syndecan PF01034.20 CBY07684.1 - 0.0048 16.8 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Tweety PF04906.13 CBY07684.1 - 0.0051 15.5 0.0 0.0064 15.2 0.0 1.1 1 0 0 1 1 1 1 Tweety FAD_SOX PF18371.1 CBY07684.1 - 0.041 14.2 0.1 0.066 13.6 0.1 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF4199 PF13858.6 CBY07684.1 - 0.1 13.0 0.6 0.19 12.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4407 PF14362.6 CBY07684.1 - 0.11 11.9 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pet100 PF09803.9 CBY07684.1 - 0.15 12.6 1.9 0.26 11.8 0.2 2.1 1 1 1 2 2 2 0 Pet100 Mitofilin PF09731.9 CBY07684.1 - 0.2 10.5 5.0 0.24 10.2 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TSC22 PF01166.18 CBY07684.1 - 0.51 10.7 4.6 1.3 9.4 4.6 1.7 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF1640 PF07798.11 CBY07684.1 - 4.9 7.2 8.2 7.2 6.6 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) SH3_9 PF14604.6 CBY07685.1 - 5.7e-05 22.9 0.0 0.17 11.8 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 CBY07685.1 - 0.0001 21.9 0.1 0.18 11.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CBY07685.1 - 0.00013 21.4 0.1 0.27 10.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain DUF3456 PF11938.8 CBY07686.1 - 2.7e-07 31.2 5.0 0.00069 20.2 2.2 3.2 2 2 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.13 CBY07686.1 - 0.0014 19.0 13.4 0.0014 19.0 13.4 4.0 4 1 0 4 4 4 1 EGF-like domain MbeD_MobD PF04899.12 CBY07687.1 - 0.32 11.2 2.7 0.79 9.9 2.7 1.6 1 0 0 1 1 1 0 MbeD/MobD like MFS_1 PF07690.16 CBY07688.1 - 4.6e-34 117.9 24.5 9.1e-31 107.0 21.4 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily DLH PF01738.18 CBY07689.1 - 1.9e-05 24.4 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Gamma-thionin PF00304.20 CBY07689.1 - 6.2 7.2 7.4 2 8.7 0.8 2.3 2 0 0 2 2 2 0 Gamma-thionin family PTR2 PF00854.21 CBY07690.1 - 1.4e-90 304.0 11.4 8.8e-79 265.1 6.5 2.3 2 0 0 2 2 2 2 POT family DUF4452 PF14618.6 CBY07690.1 - 6.3 6.6 7.9 0.33 10.8 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4452) IL2 PF00715.17 CBY07691.1 - 0.0056 16.6 2.2 0.02 14.8 2.2 1.7 1 1 0 1 1 1 1 Interleukin 2 RLL PF10036.9 CBY07691.1 - 0.023 14.6 1.4 0.025 14.4 1.4 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Ku_PK_bind PF08785.11 CBY07691.1 - 0.048 13.8 3.6 0.062 13.5 3.6 1.3 1 0 0 1 1 1 0 Ku C terminal domain like DUF745 PF05335.13 CBY07691.1 - 0.38 10.5 1.1 0.54 10.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) VWC PF00093.18 CBY07692.1 - 0.045 14.1 0.2 0.045 14.1 0.2 6.9 4 2 1 5 5 5 0 von Willebrand factor type C domain DUF2625 PF10946.8 CBY07692.1 - 0.091 11.8 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2625 2OG-FeII_Oxy PF03171.20 CBY07693.1 - 3.7e-19 69.1 0.0 7.1e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBY07693.1 - 2.4e-10 41.2 1.2 2.4e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Hydrolase PF00702.26 CBY07694.1 - 0.00013 22.4 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Atg31 PF09795.9 CBY07694.1 - 0.053 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein 31 TFIIA PF03153.13 CBY07695.1 - 0.013 15.6 24.5 0.018 15.1 24.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAP_GLY PF01302.25 CBY07696.1 - 2.8e-12 46.5 0.1 4.6e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain CCDC106 PF15794.5 CBY07696.1 - 7.4 6.2 15.7 6.1 6.5 7.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Syndecan PF01034.20 CBY07697.1 - 0.04 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF5305 PF17231.2 CBY07697.1 - 0.08 12.3 0.1 0.08 12.3 0.1 1.7 2 1 0 2 2 2 0 Family of unknown function (DUF5305) DUF2970 PF11174.8 CBY07697.1 - 0.89 9.5 3.3 1.5 8.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Lectin_C PF00059.21 CBY07697.1 - 3.6 8.4 7.8 0.65 10.8 3.2 2.2 2 1 0 2 2 2 0 Lectin C-type domain Tom7 PF08038.12 CBY07698.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 TOM7 family fn3 PF00041.21 CBY07699.1 - 3.1e-05 24.2 0.1 0.00041 20.6 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III domain fn3 PF00041.21 CBY07700.1 - 2.1e-24 85.7 4.4 8.1e-06 26.1 0.1 5.4 5 0 0 5 5 5 5 Fibronectin type III domain Fibrinogen_C PF00147.18 CBY07700.1 - 1.1e-19 71.2 0.0 1.7e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF2369 PF10179.9 CBY07700.1 - 0.00058 20.2 2.0 1.8 9.0 0.1 4.2 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 CBY07700.1 - 0.00069 19.7 0.1 0.074 13.2 0.1 2.7 2 0 0 2 2 2 1 Fibronectin type III domain Interfer-bind PF09294.10 CBY07700.1 - 0.0012 19.2 7.0 5.6 7.3 0.0 5.3 4 1 1 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III Sec-ASP3 PF15432.6 CBY07700.1 - 0.0021 18.2 1.2 0.34 11.1 0.0 4.0 3 1 1 4 4 4 1 Accessory Sec secretory system ASP3 Glyco_hydro_36C PF16874.5 CBY07700.1 - 0.003 18.0 0.0 6.5 7.3 0.0 4.2 5 1 0 5 5 5 1 Glycosyl hydrolase family 36 C-terminal domain CarboxypepD_reg PF13620.6 CBY07700.1 - 0.0071 16.6 1.0 0.35 11.2 0.1 3.1 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Big_10 PF17964.1 CBY07700.1 - 0.043 13.8 0.1 2.8 7.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial Ig domain TQ PF18202.1 CBY07700.1 - 0.1 13.1 0.0 6.6 7.3 0.0 3.1 3 0 0 3 3 3 0 T-Q ester bond containing domain Ank_2 PF12796.7 CBY07701.1 - 0.016 15.8 0.0 0.026 15.1 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY07701.1 - 0.04 14.3 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Glutaminase PF04960.15 CBY07702.1 - 5e-92 308.1 0.3 6.4e-92 307.8 0.3 1.1 1 0 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 CBY07702.1 - 3.2e-07 30.6 0.9 1.1e-06 28.8 0.1 2.3 3 0 0 3 3 3 1 EF-hand domain Ank_2 PF12796.7 CBY07702.1 - 0.082 13.5 0.1 0.77 10.4 0.1 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) IU_nuc_hydro PF01156.19 CBY07703.1 - 7.6e-55 186.6 0.0 8.9e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase COesterase PF00135.28 CBY07704.1 - 1.1e-92 311.5 0.0 3.2e-92 310.1 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY07704.1 - 6.5e-11 42.5 0.1 5.2e-10 39.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY07704.1 - 0.00025 20.6 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DnaJ PF00226.31 CBY07706.1 - 8.3e-16 57.9 1.4 8.3e-16 57.9 1.4 1.9 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.6 CBY07706.1 - 0.001 19.0 0.1 0.25 11.3 0.0 2.5 2 0 0 2 2 2 2 A repeated domain in UCH-protein GTP_EFTU PF00009.27 CBY07707.1 - 1.4e-32 112.9 0.3 1.9e-32 112.4 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY07707.1 - 3.2e-07 30.4 0.1 7.4e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CBY07707.1 - 7.8e-07 29.4 0.2 2.4e-06 27.9 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.19 CBY07707.1 - 8.5e-05 22.2 2.4 0.00026 20.7 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 CBY07707.1 - 0.00043 19.7 0.4 0.001 18.5 0.4 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CBY07707.1 - 0.0011 18.5 0.5 0.0037 16.7 0.5 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBY07707.1 - 0.0011 18.5 0.3 0.002 17.6 0.3 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBY07707.1 - 0.0028 16.9 2.5 0.61 9.2 0.3 2.5 2 0 0 2 2 2 2 G-protein alpha subunit PduV-EutP PF10662.9 CBY07707.1 - 0.025 14.3 0.5 0.8 9.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 CBY07707.1 - 0.033 13.7 3.0 4.4 6.8 1.9 3.1 2 1 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBY07707.1 - 0.053 13.4 0.1 0.053 13.4 0.1 2.5 3 0 0 3 3 3 0 RsgA GTPase ATP_bind_1 PF03029.17 CBY07707.1 - 0.065 13.0 2.9 10 5.8 0.1 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 CBY07707.1 - 0.081 12.2 1.1 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Septin Ufd2P_core PF10408.9 CBY07708.1 - 6e-149 497.5 22.5 8.6e-149 497.0 22.5 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CBY07708.1 - 5.8e-23 80.9 0.6 1.9e-22 79.2 0.2 2.3 2 0 0 2 2 2 1 U-box domain Init_tRNA_PT PF04179.12 CBY07708.1 - 0.13 12.5 0.8 13 6.2 0.4 2.8 2 0 0 2 2 2 0 Rit1 DUSP-like domain His_Phos_2 PF00328.22 CBY07709.1 - 2.8e-09 36.8 0.4 6.9e-08 32.2 0.0 2.6 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) 7tm_1 PF00001.21 CBY07710.1 - 5.5e-14 52.1 9.2 5.7e-14 52.1 4.7 2.5 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Sigma_reg_N PF13800.6 CBY07710.1 - 3.7 7.9 10.9 0.48 10.8 1.1 3.0 2 1 0 2 2 2 0 Sigma factor regulator N-terminal SNF PF00209.18 CBY07711.1 - 4.5e-163 543.7 34.8 5.5e-163 543.4 34.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SUIM_assoc PF16619.5 CBY07713.1 - 0.005 16.9 6.2 0.0093 16.0 6.2 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Dicty_REP PF05086.12 CBY07714.1 - 5.5 4.8 9.5 11 3.8 9.5 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HisG_C PF08029.11 CBY07715.1 - 0.0066 16.6 0.1 6.4 7.0 0.0 2.7 3 0 0 3 3 3 2 HisG, C-terminal domain YTV PF07639.11 CBY07715.1 - 0.061 13.4 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 YTV Glyco_transf_7N PF13733.6 CBY07721.1 - 1.3e-52 177.0 0.7 2.2e-52 176.2 0.7 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY07721.1 - 7.1e-20 70.5 0.0 1.7e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Cys_knot PF00007.22 CBY07721.1 - 0.02 15.2 0.5 0.04 14.2 0.5 1.6 1 0 0 1 1 1 0 Cystine-knot domain Ion_trans_2 PF07885.16 CBY07722.1 - 2.3e-08 33.9 0.0 2.6e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CBY07722.1 - 6.3e-06 25.6 0.0 7.4e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Ion transport protein TSP_C PF05735.12 CBY07723.1 - 3.5e-89 298.0 0.4 5e-89 297.5 0.4 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 CBY07723.1 - 5e-29 99.7 104.3 8.1e-15 54.2 13.1 8.3 7 1 1 8 8 8 7 Thrombospondin type 3 repeat EGF_3 PF12947.7 CBY07723.1 - 0.0047 17.1 9.0 0.0047 17.1 9.0 9.7 8 1 0 8 8 8 3 EGF domain Pkinase PF00069.25 CBY07724.1 - 1.2e-62 211.7 0.0 2.2e-62 210.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CBY07724.1 - 1e-39 134.5 0.1 3.3e-20 71.9 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY07724.1 - 1.4e-24 86.8 0.0 2.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Med4 PF10018.9 CBY07724.1 - 0.00073 19.3 1.5 0.0014 18.4 1.5 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Kinase-like PF14531.6 CBY07724.1 - 0.00079 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CBY07724.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Sec2p PF06428.11 CBY07724.1 - 0.0078 16.2 2.4 0.02 14.9 2.4 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p APH PF01636.23 CBY07724.1 - 0.0097 15.8 0.0 0.093 12.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CsgF PF10614.9 CBY07724.1 - 0.028 14.6 2.6 0.31 11.2 0.8 2.9 3 0 0 3 3 3 0 Type VIII secretion system (T8SS), CsgF protein Cep57_MT_bd PF06657.13 CBY07724.1 - 0.034 14.6 1.0 0.11 13.0 1.0 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Glutaredoxin2_C PF04399.13 CBY07724.1 - 0.082 12.7 0.4 0.18 11.6 0.4 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF3837 PF12939.7 CBY07724.1 - 0.19 12.1 1.7 1.2 9.6 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) DUF2570 PF10828.8 CBY07724.1 - 0.21 11.4 1.9 0.6 9.9 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) BAAT_C PF08840.11 CBY07725.1 - 1.3e-06 28.5 0.1 2.8e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 CBY07725.1 - 0.027 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.8 CBY07725.1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 CBY07725.1 - 0.041 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S10 PF00450.22 CBY07726.1 - 1.8e-124 416.4 2.8 2.1e-124 416.2 2.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 CBY07726.1 - 0.08 12.4 0.6 6.5 6.2 0.0 3.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family Spem1 PF15670.5 CBY07727.1 - 8.6 5.9 11.6 3.1 7.3 8.1 1.7 2 0 0 2 2 2 0 Spermatid maturation protein 1 Actin PF00022.19 CBY07728.1 - 3.8e-88 295.8 0.0 4.5e-87 292.3 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBY07728.1 - 0.00017 20.5 0.0 0.013 14.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF3100 PF11299.8 CBY07728.1 - 0.085 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) F-box-like PF12937.7 CBY07729.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like BURP PF03181.15 CBY07729.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 BURP domain PCRF PF03462.18 CBY07730.1 - 6.1e-11 42.6 0.1 6.1e-11 42.6 0.1 2.1 2 1 0 2 2 2 1 PCRF domain Glutaminase PF04960.15 CBY07731.1 - 3e-85 285.9 0.0 4.7e-85 285.2 0.0 1.2 1 0 0 1 1 1 1 Glutaminase U3_assoc_6 PF08640.11 CBY07731.1 - 0.076 13.1 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 O-FucT PF10250.9 CBY07733.1 - 1.3e-06 28.3 0.0 2.6e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TetR_C_8 PF14278.6 CBY07733.1 - 0.019 15.1 0.1 0.072 13.2 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region PDZ PF00595.24 CBY07734.1 - 8.6e-10 38.8 0.2 2.3e-06 27.9 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 CBY07734.1 - 9e-10 38.7 0.0 2.1e-06 28.0 0.0 3.4 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 CBY07734.1 - 2.9e-08 33.4 0.1 0.00038 20.2 0.0 3.6 4 0 0 4 4 4 2 PDZ domain Trypan_PARP PF05887.11 CBY07734.1 - 0.12 12.4 8.8 0.21 11.6 8.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) La PF05383.17 CBY07735.1 - 1.3e-08 34.8 0.0 2.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY07735.1 - 2.4e-05 24.0 0.2 0.14 12.0 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_2 PF03567.14 CBY07736.1 - 0.006 16.5 0.4 0.006 16.5 0.4 2.0 2 1 0 2 2 2 1 Sulfotransferase family X8 PF07983.13 CBY07736.1 - 0.13 13.0 2.0 0.14 12.9 0.1 1.9 2 0 0 2 2 2 0 X8 domain Kelch_1 PF01344.25 CBY07737.1 - 1.3e-05 24.7 6.0 0.00035 20.1 0.8 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBY07737.1 - 0.0002 21.5 0.7 0.0082 16.4 0.1 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY07737.1 - 0.0097 15.9 1.7 4.7 7.3 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY07737.1 - 0.34 11.0 9.9 4.2 7.5 0.0 4.4 4 0 0 4 4 4 0 Kelch motif Amidohydro_1 PF01979.20 CBY07738.1 - 1.5e-64 218.5 0.0 1.7e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBY07738.1 - 1.2e-09 38.2 0.1 9.6e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family MTA_R1 PF17226.2 CBY07739.1 - 0.0046 17.1 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 MTA R1 domain zf-C2H2 PF00096.26 CBY07740.1 - 9.9e-16 57.2 56.0 1.1e-05 25.6 0.7 8.0 9 0 0 9 9 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY07740.1 - 2.9e-15 55.6 55.8 0.00051 20.7 0.3 8.6 8 1 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY07740.1 - 5e-14 52.2 45.1 0.00016 21.8 0.5 8.0 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY07740.1 - 1e-08 35.2 49.5 0.0017 18.7 1.0 8.3 9 0 0 9 9 8 5 Zinc-finger double domain zf-met PF12874.7 CBY07740.1 - 6.2e-08 32.8 37.1 0.044 14.2 2.8 6.8 7 0 0 7 7 7 5 Zinc-finger of C2H2 type Tup_N PF08581.10 CBY07740.1 - 0.27 11.5 6.5 0.67 10.3 6.5 1.6 1 0 0 1 1 1 0 Tup N-terminal zinc_ribbon_15 PF17032.5 CBY07740.1 - 0.29 11.9 28.6 0.15 12.9 2.1 4.9 4 1 1 5 5 5 0 zinc-ribbon family zf-C2H2_6 PF13912.6 CBY07740.1 - 0.3 11.1 31.2 1.2 9.3 0.2 6.2 6 0 0 6 6 5 0 C2H2-type zinc finger PyrI_C PF02748.15 CBY07740.1 - 1.3 9.0 20.7 1.3 9.0 0.3 5.7 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.9 CBY07740.1 - 1.4 9.1 8.7 8.4 6.5 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.7 CBY07740.1 - 3.2 7.8 24.2 6 7.0 1.3 4.9 4 2 0 4 4 4 0 Double zinc ribbon zf-C2H2_8 PF15909.5 CBY07740.1 - 3.7 7.9 17.0 14 6.0 5.1 3.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 CBY07740.1 - 4.3 7.5 27.2 0.11 12.6 0.8 5.6 3 1 4 7 7 7 0 Zinc ribbon domain RIB43A PF05914.12 CBY07741.1 - 2.6e-122 408.2 63.9 3e-122 408.0 63.9 1.0 1 0 0 1 1 1 1 RIB43A Ubiq_cyt_C_chap PF03981.12 CBY07742.1 - 9.1e-05 22.6 0.4 0.00018 21.6 0.4 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Tudor-knot PF11717.8 CBY07742.1 - 0.015 15.2 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain CactinC_cactus PF09732.9 CBY07743.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PH PF00169.29 CBY07744.1 - 5.7e-08 33.2 0.3 1.4e-07 31.9 0.3 1.7 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 CBY07744.1 - 7.4e-08 32.9 0.0 1.6e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein anillin PH_9 PF15410.6 CBY07744.1 - 0.0081 16.5 0.4 0.16 12.3 0.1 3.1 2 2 0 2 2 2 1 Pleckstrin homology domain CactinC_cactus PF09732.9 CBY07745.1 - 1.8e-55 186.3 9.5 3.5e-55 185.3 9.5 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 CBY07745.1 - 1e-50 172.2 6.5 1e-50 172.2 6.5 2.9 3 0 0 3 3 3 1 Conserved mid region of cactin DUF2178 PF09946.9 CBY07746.1 - 2.2 8.5 10.0 7.2 6.8 2.3 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) CPBP PF02517.16 CBY07746.1 - 3.1 8.2 7.7 3.9 7.9 2.6 2.1 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease Sec63 PF02889.16 CBY07747.1 - 5e-164 543.7 3.9 1.7e-90 302.6 3.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBY07747.1 - 5.5e-42 143.5 0.0 1.1e-25 90.4 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CBY07747.1 - 1.4e-31 109.0 5.3 5.6e-31 107.0 3.8 2.6 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 CBY07747.1 - 3.6e-21 75.9 0.8 4.1e-13 49.7 0.0 3.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBY07747.1 - 5e-08 33.3 0.1 0.00014 22.1 0.0 4.4 4 1 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CBY07747.1 - 2.4e-05 24.6 0.4 0.007 16.6 0.0 3.8 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CBY07747.1 - 0.0037 16.4 0.0 2.9 6.9 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein EloA-BP1 PF15870.5 CBY07748.1 - 1.1e-15 58.3 0.1 1.1e-15 58.3 0.1 2.5 2 0 0 2 2 2 1 ElonginA binding-protein 1 CHORD PF04968.12 CBY07748.1 - 2.1 9.1 7.0 5.5 7.8 7.0 1.6 1 0 0 1 1 1 0 CHORD MDM10 PF12519.8 CBY07748.1 - 4.6 6.0 10.2 7.2 5.4 10.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 MCM3AP_GANP PF16769.5 CBY07748.1 - 5.5 5.1 11.2 8.1 4.6 11.2 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Dynamin_M PF01031.20 CBY07749.1 - 2.5e-95 319.0 2.6 2.5e-95 319.0 2.6 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CBY07749.1 - 1e-54 185.1 0.2 6.3e-54 182.5 0.0 2.4 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 CBY07749.1 - 2.5e-22 78.8 3.0 7.9e-22 77.2 3.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 CBY07749.1 - 1.7e-10 41.3 0.4 3.8e-10 40.2 0.4 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 CBY07749.1 - 0.00021 21.3 0.0 0.00078 19.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY07749.1 - 0.016 15.6 0.0 0.88 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain ApoO PF09769.9 CBY07749.1 - 0.046 13.7 0.3 0.83 9.6 0.1 2.5 2 0 0 2 2 2 0 Apolipoprotein O DUF2780 PF11075.8 CBY07749.1 - 0.094 12.9 0.2 0.094 12.9 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) RasGAP PF00616.19 CBY07749.1 - 0.58 9.8 3.5 0.45 10.2 1.1 2.1 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase SNF2_N PF00176.23 CBY07750.1 - 1.1e-57 195.4 0.0 2.4e-57 194.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY07750.1 - 1.4e-17 64.0 0.0 4.1e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3535 PF12054.8 CBY07750.1 - 2e-12 47.1 1.2 4.4e-05 22.9 0.0 5.0 4 1 1 5 5 5 3 Domain of unknown function (DUF3535) Vac14_Fab1_bd PF12755.7 CBY07750.1 - 0.0047 17.5 0.5 0.53 10.9 0.0 3.6 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region CID_GANP PF16766.5 CBY07750.1 - 0.15 12.3 0.1 0.58 10.4 0.1 2.1 1 0 0 1 1 1 0 Binding region of GANP to ENY2 Pou PF00157.17 CBY07751.1 - 3.5e-31 107.0 0.0 7.6e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY07751.1 - 5.2e-17 61.4 2.0 1.1e-16 60.3 2.0 1.6 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CBY07751.1 - 1.5e-05 25.2 0.1 0.00093 19.5 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 CBY07751.1 - 0.096 12.8 0.1 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix Homeobox_KN PF05920.11 CBY07751.1 - 0.13 12.1 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF4770 PF15994.5 CBY07751.1 - 0.14 12.4 2.1 0.24 11.6 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Limkain-b1 PF11608.8 CBY07753.1 - 3.4e-41 139.2 0.2 8e-41 138.0 0.2 1.7 1 0 0 1 1 1 1 Limkain b1 OST-HTH PF12872.7 CBY07753.1 - 4.4e-19 68.1 1.9 7.9e-10 38.4 0.0 5.4 6 1 0 6 6 6 3 OST-HTH/LOTUS domain NYN PF01936.18 CBY07753.1 - 4.4e-18 66.2 0.2 1.1e-17 64.9 0.2 1.6 1 0 0 1 1 1 1 NYN domain RRM_1 PF00076.22 CBY07753.1 - 1.1e-05 25.2 0.0 0.0011 18.7 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4404 PF14357.6 CBY07753.1 - 0.14 12.8 2.3 2 9.1 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) PCNA_C PF02747.15 CBY07754.1 - 9.1e-53 177.8 0.0 1.9e-52 176.8 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 CBY07754.1 - 4.7e-47 158.9 2.0 7.1e-47 158.3 2.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 CBY07754.1 - 0.0016 17.9 0.0 0.0022 17.5 0.0 1.3 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.12 CBY07754.1 - 0.042 12.9 0.0 0.062 12.4 0.0 1.5 1 1 0 1 1 1 0 Hus1-like protein Homeodomain PF00046.29 CBY07755.1 - 8.2e-22 76.8 7.1 1.5e-21 76.0 7.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY07755.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.3 3 0 0 3 3 3 0 Homeobox KN domain Mucin PF01456.17 CBY07756.1 - 8.5e-05 22.6 28.6 0.00012 22.1 28.6 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF5401 PF17380.2 CBY07756.1 - 0.067 11.3 2.5 0.082 11.0 2.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) FNIP_N PF14636.6 CBY07756.1 - 0.76 10.7 4.4 1.2 10.1 4.4 1.4 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus Dicty_REP PF05086.12 CBY07756.1 - 0.83 7.6 11.6 1.3 6.9 11.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 CBY07756.1 - 1.4 7.0 10.1 1.6 6.8 10.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SecE PF00584.20 CBY07758.1 - 0.18 11.7 0.9 0.39 10.7 0.9 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Na_Ca_ex PF01699.24 CBY07759.1 - 1.7e-40 138.4 36.9 6.7e-23 81.3 11.5 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein CUB PF00431.20 CBY07760.1 - 1.4e-05 25.3 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 CUB domain ITI_HC_C PF06668.12 CBY07761.1 - 0.0053 16.4 0.0 0.017 14.8 0.0 1.9 1 1 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus SH3BP5 PF05276.14 CBY07762.1 - 1.9e-15 57.3 3.3 3e-15 56.6 3.3 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) MscS_porin PF12795.7 CBY07762.1 - 0.0027 17.3 10.4 0.0057 16.2 1.6 2.1 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain ZapB PF06005.12 CBY07762.1 - 0.0054 17.1 11.4 0.033 14.6 0.6 2.6 2 1 0 2 2 2 1 Cell division protein ZapB KASH_CCD PF14662.6 CBY07762.1 - 0.012 15.4 7.1 0.2 11.5 1.2 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 CBY07762.1 - 0.034 14.2 4.1 0.034 14.2 4.1 2.6 3 0 0 3 3 2 0 TolA binding protein trimerisation DivIC PF04977.15 CBY07762.1 - 0.038 13.7 5.8 0.96 9.3 0.4 2.6 2 0 0 2 2 2 0 Septum formation initiator NRBF2 PF08961.10 CBY07762.1 - 0.042 13.4 2.3 0.48 10.0 0.1 2.2 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator K-box PF01486.17 CBY07762.1 - 0.096 12.9 7.8 3.2 8.0 0.6 2.6 2 0 0 2 2 2 0 K-box region Cep57_CLD_2 PF14197.6 CBY07762.1 - 0.12 12.5 6.4 1.5 8.9 0.7 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Nnf1 PF03980.14 CBY07762.1 - 0.12 12.8 4.9 2.7 8.4 0.1 2.7 3 0 0 3 3 2 0 Nnf1 FUSC PF04632.12 CBY07762.1 - 0.13 10.8 1.0 0.17 10.4 1.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FtsL PF04999.13 CBY07762.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.3 3 0 0 3 3 3 0 Cell division protein FtsL CENP-H PF05837.12 CBY07762.1 - 0.21 12.0 9.6 0.13 12.7 3.6 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) GIT_CC PF16559.5 CBY07762.1 - 0.22 11.4 8.5 0.21 11.5 2.8 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRKG1_interact PF15898.5 CBY07762.1 - 0.38 11.7 0.2 0.38 11.7 0.2 2.8 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain bZIP_1 PF00170.21 CBY07762.1 - 0.43 10.7 7.5 2.4 8.3 1.4 2.6 2 0 0 2 2 2 0 bZIP transcription factor YlqD PF11068.8 CBY07762.1 - 1.1 9.7 5.7 2.1 8.7 1.3 2.2 2 0 0 2 2 2 0 YlqD protein BRE1 PF08647.11 CBY07762.1 - 1.6 8.9 7.9 0.16 12.1 2.5 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CtIP_N PF10482.9 CBY07762.1 - 7.4 6.6 11.5 1.1 9.3 2.2 2.6 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain SH3BP5 PF05276.14 CBY07763.1 - 1.5e-15 57.7 3.7 2.1e-15 57.2 3.7 1.1 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) UvsY PF11056.8 CBY07763.1 - 0.024 15.0 0.9 0.034 14.5 0.9 1.4 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY sCache_like PF16736.5 CBY07763.1 - 0.031 14.4 0.4 0.051 13.7 0.4 1.4 1 0 0 1 1 1 0 Single Cache-like Glyco_transf_88 PF16849.5 CBY07763.1 - 0.034 13.1 0.5 0.036 13.0 0.5 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 88 ImpA_N PF06812.12 CBY07763.1 - 0.04 14.0 0.3 0.068 13.3 0.2 1.5 1 1 0 1 1 1 0 ImpA, N-terminal, type VI secretion system DUF4726 PF15855.5 CBY07763.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) Laminin_II PF06009.12 CBY07763.1 - 0.2 11.7 4.3 0.25 11.4 4.3 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF2951 PF11166.8 CBY07763.1 - 0.71 10.1 3.9 1.8 8.8 3.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) PRKCSH-like PF12999.7 CBY07763.1 - 1.2 8.9 4.4 0.74 9.6 2.0 1.7 1 1 1 2 2 2 0 Glucosidase II beta subunit-like Ets PF00178.22 CBY07766.1 - 7.3e-15 55.2 0.2 1.2e-14 54.5 0.2 1.3 1 0 0 1 1 1 1 Ets-domain HMG_box_2 PF09011.10 CBY07766.1 - 0.059 14.0 0.6 0.099 13.3 0.0 1.7 2 1 0 2 2 2 0 HMG-box domain Collagen PF01391.18 CBY07767.1 - 1e-65 217.3 305.2 4.9e-08 32.6 37.0 9.7 2 2 5 7 7 7 5 Collagen triple helix repeat (20 copies) MAGI_u5 PF16666.5 CBY07767.1 - 0.19 11.9 8.9 0.53 10.4 8.9 1.8 1 1 0 1 1 1 0 Unstructured region on MAGI Rrn6 PF10214.9 CBY07767.1 - 1.7 7.1 12.2 2.4 6.6 12.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4692 PF15763.5 CBY07767.1 - 5.7 7.4 9.3 12 6.4 9.3 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DDRGK PF09756.9 CBY07767.1 - 7 6.2 11.0 10 5.7 11.0 1.1 1 0 0 1 1 1 0 DDRGK domain ABC_membrane PF00664.23 CBY07768.1 - 1.2e-93 313.8 16.6 5.7e-52 177.1 6.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY07768.1 - 1.3e-70 236.3 0.1 6.7e-34 117.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBY07768.1 - 1.5e-17 63.8 0.4 1.2e-06 28.2 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY07768.1 - 6.5e-10 39.2 0.2 0.00021 21.2 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 CBY07768.1 - 1.7e-09 38.1 1.1 0.0022 18.3 0.2 3.7 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CBY07768.1 - 4.7e-09 36.4 0.1 0.00015 21.6 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 CBY07768.1 - 1.1e-07 31.0 0.3 0.0059 15.5 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 CBY07768.1 - 6.3e-07 29.9 2.6 0.0011 19.4 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 CBY07768.1 - 1.7e-05 24.9 3.5 0.27 11.5 0.3 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CBY07768.1 - 4.1e-05 23.2 0.3 0.33 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CBY07768.1 - 6.3e-05 22.3 0.1 0.47 9.7 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin Rad17 PF03215.15 CBY07768.1 - 0.00011 22.2 0.3 0.54 10.2 0.1 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_30 PF13604.6 CBY07768.1 - 0.00014 21.6 0.8 0.3 10.8 0.1 3.3 3 1 0 3 3 3 2 AAA domain G-alpha PF00503.20 CBY07768.1 - 0.00043 19.5 1.6 0.65 9.1 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit AAA PF00004.29 CBY07768.1 - 0.00052 20.4 1.6 2.7 8.4 0.2 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBY07768.1 - 0.00088 19.3 0.1 0.48 10.4 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) PRK PF00485.18 CBY07768.1 - 0.0012 18.6 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 CBY07768.1 - 0.0028 17.2 0.2 0.45 10.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CBY07768.1 - 0.0032 17.8 0.0 5.1 7.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 CBY07768.1 - 0.0033 17.0 0.1 3 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CBY07768.1 - 0.0089 15.2 0.0 0.77 8.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_21 PF13304.6 CBY07768.1 - 0.013 15.3 0.5 6.5 6.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CBY07768.1 - 0.014 16.0 0.0 3.3 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 CBY07768.1 - 0.02 13.8 0.0 2.2 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain DUF2795 PF11387.8 CBY07768.1 - 0.027 14.7 0.4 2.6 8.3 0.1 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF2795) ATP-synt_ab PF00006.25 CBY07768.1 - 0.048 13.3 0.7 7.7 6.1 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 CBY07768.1 - 0.051 13.7 0.0 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase tRNA_lig_kinase PF08303.11 CBY07768.1 - 0.077 13.1 0.1 6.9 6.7 0.0 2.7 2 0 0 2 2 2 0 tRNA ligase kinase domain NB-ARC PF00931.22 CBY07768.1 - 0.077 12.2 0.6 16 4.6 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain Viral_helicase1 PF01443.18 CBY07768.1 - 0.16 11.7 0.1 16 5.2 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 CBY07768.1 - 0.16 11.3 0.4 13 5.1 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.6 CBY07768.1 - 0.17 12.0 0.1 16 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Tub_N PF16322.5 CBY07768.1 - 0.33 11.3 5.7 0.54 10.6 5.7 1.3 1 0 0 1 1 1 0 Tubby N-terminal AAA_23 PF13476.6 CBY07768.1 - 0.59 10.6 11.0 2.8 8.4 0.1 3.4 3 0 0 3 3 3 0 AAA domain MtrF PF09472.10 CBY07768.1 - 2.7 7.4 4.7 1.2 8.6 0.2 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Trypsin PF00089.26 CBY07771.1 - 2.8e-40 138.5 0.0 4.6e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY07771.1 - 7.1e-06 26.4 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY07771.1 - 0.00013 22.9 0.0 0.00031 21.7 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Fam20C PF06702.12 CBY07772.1 - 6.8e-84 281.1 0.1 1.1e-83 280.4 0.1 1.3 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 CBY07772.1 - 0.066 12.1 0.0 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 FAM198 protein Mucin PF01456.17 CBY07772.1 - 0.48 10.4 12.3 0.77 9.7 12.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Fibrinogen_C PF00147.18 CBY07773.1 - 6.9e-89 297.4 26.7 1.4e-47 162.4 9.1 2.1 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain TED_complement PF07678.14 CBY07776.1 - 1.9e-62 211.1 0.0 3.2e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 CBY07776.1 - 2.8e-28 97.6 0.1 1.4e-27 95.4 0.1 2.3 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 CBY07776.1 - 4.3e-21 75.7 1.0 6e-18 65.6 0.1 3.1 2 0 0 2 2 2 2 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 CBY07776.1 - 2.4e-11 43.8 0.3 3.3e-10 40.1 0.0 3.0 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG2 PF01835.19 CBY07776.1 - 3.9e-11 43.2 0.1 1.3e-10 41.6 0.1 1.9 1 0 0 1 1 1 1 MG2 domain A2M_recep PF07677.14 CBY07776.1 - 2.1e-09 37.9 2.6 3.7e-09 37.2 0.2 2.7 3 0 0 3 3 3 1 A-macroglobulin receptor binding domain ECH_1 PF00378.20 CBY07777.1 - 5.4e-15 55.4 0.0 6.4e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY07777.1 - 8.6e-10 38.6 0.0 9.9e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBY07778.1 - 7e-30 104.2 0.2 7.7e-30 104.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY07778.1 - 7.2e-11 42.2 1.5 3.3e-07 30.1 0.9 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase zf-C2H2 PF00096.26 CBY07779.1 - 7.2e-17 60.8 46.9 0.00085 19.6 0.7 7.6 7 1 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY07779.1 - 5.1e-16 58.3 34.8 0.00074 19.8 0.1 6.5 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY07779.1 - 6e-13 48.4 47.6 0.0092 16.7 1.5 8.7 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY07779.1 - 7.6e-10 38.8 53.9 0.00053 20.2 1.6 8.5 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CBY07779.1 - 4.8e-06 26.8 21.1 0.017 15.4 4.5 4.3 4 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 CBY07779.1 - 1.4e-05 25.8 22.7 0.18 12.5 0.1 5.5 4 1 1 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CBY07779.1 - 8.7e-05 22.8 50.0 0.022 15.2 0.3 8.9 9 0 0 9 9 9 4 Zinc-finger of C2H2 type GAGA PF09237.11 CBY07779.1 - 0.019 14.7 0.2 0.21 11.4 0.1 2.7 2 0 0 2 2 2 0 GAGA factor zf-C2H2_11 PF16622.5 CBY07779.1 - 0.025 14.3 0.2 0.025 14.3 0.2 5.6 7 0 0 7 7 6 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 CBY07779.1 - 0.038 14.3 0.9 0.038 14.3 0.9 3.1 2 1 0 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CBY07779.1 - 0.15 12.1 27.1 0.21 11.6 0.3 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CBY07779.1 - 0.42 11.0 28.2 0.39 11.1 2.2 5.4 3 1 3 6 6 5 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CBY07779.1 - 1.1 9.3 31.3 0.61 10.2 0.9 5.4 4 1 1 5 5 5 0 BED zinc finger zf-H2C2_5 PF13909.6 CBY07779.1 - 2.6 7.9 32.8 1.2 9.0 0.2 5.9 5 2 0 5 5 5 0 C2H2-type zinc-finger domain HalOD2 PF18547.1 CBY07779.1 - 3.1 7.8 5.9 5.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Halobacterial output domain 2 CpXC PF14353.6 CBY07779.1 - 4.7 7.3 12.1 0.81 9.7 1.0 3.5 1 1 2 3 3 3 0 CpXC protein Gram_pos_anchor PF00746.21 CBY07780.1 - 0.0064 16.4 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 LPXTG cell wall anchor motif Syndecan PF01034.20 CBY07780.1 - 0.053 13.4 0.1 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain MraZ PF02381.18 CBY07781.1 - 0.076 13.0 0.1 0.095 12.7 0.1 1.1 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like TPR_2 PF07719.17 CBY07782.1 - 2.7e-10 39.5 5.6 8.4e-05 22.4 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY07782.1 - 5.2e-10 39.5 3.0 2.8e-05 24.3 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY07782.1 - 5.3e-08 32.4 2.6 2.2e-05 24.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBY07782.1 - 1.4e-07 30.9 0.4 1.4e-07 30.9 0.4 2.1 2 0 0 2 2 2 1 SHNi-TPR TPR_8 PF13181.6 CBY07782.1 - 3.9e-06 26.6 3.4 0.044 14.0 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY07782.1 - 0.0012 19.4 0.1 16 6.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY07782.1 - 0.0016 19.0 2.0 0.84 10.3 0.7 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY07782.1 - 0.009 16.5 2.0 0.24 12.0 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY07782.1 - 0.012 15.4 0.1 0.96 9.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY07782.1 - 0.013 15.1 0.2 4.7 7.0 0.0 2.7 2 0 0 2 2 2 0 TPR repeat NPV_P10 PF05531.12 CBY07782.1 - 0.025 15.0 0.8 0.081 13.4 0.8 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TPR_17 PF13431.6 CBY07782.1 - 0.027 14.8 0.1 42 4.8 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY07782.1 - 0.071 12.5 0.0 9.1 5.5 0.0 2.4 2 0 0 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 CBY07782.1 - 0.079 13.8 0.4 71 4.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1266 PF06889.11 CBY07782.1 - 1.8 8.6 6.8 0.99 9.4 2.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1266) PAP_PilO PF06864.12 CBY07783.1 - 0.035 12.9 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) TMEM154 PF15102.6 CBY07783.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4519 PF15012.6 CBY07783.1 - 0.21 11.8 1.4 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Sulfotransfer_2 PF03567.14 CBY07784.1 - 6.6e-23 81.9 0.9 1e-22 81.3 0.9 1.2 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 CBY07784.1 - 0.00082 18.4 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Cob_adeno_trans PF01923.18 CBY07784.1 - 0.074 13.2 0.1 0.9 9.7 0.0 2.2 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Fes1 PF08609.10 CBY07784.1 - 0.085 13.7 3.0 7.5 7.5 0.9 2.4 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Lsr2 PF11774.8 CBY07784.1 - 0.11 12.7 0.2 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Lsr2 CitG PF01874.16 CBY07784.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase UPF0020 PF01170.18 CBY07785.1 - 3e-10 40.1 0.3 1.5e-08 34.6 0.3 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CBY07785.1 - 5.5e-06 26.3 0.0 0.051 13.3 0.0 2.3 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 CBY07785.1 - 1.4e-05 24.5 0.0 2.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 N-6 DNA Methylase Aldo_ket_red PF00248.21 CBY07786.1 - 3.3e-46 157.8 0.1 4.1e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_3 PF13302.7 CBY07786.1 - 0.092 13.4 0.1 0.73 10.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DHHC PF01529.20 CBY07788.1 - 1.1e-30 106.5 15.3 1.1e-30 106.5 15.3 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase Myb_DNA-binding PF00249.31 CBY07789.1 - 0.0021 18.2 0.1 2.7 8.2 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain THOC7 PF05615.13 CBY07789.1 - 1.7 9.0 20.2 0.38 11.0 13.1 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 FapA PF03961.13 CBY07789.1 - 7.6 5.0 19.7 0.065 11.8 8.6 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Atg8 PF02991.16 CBY07790.1 - 8.6e-42 141.6 0.1 1.1e-41 141.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBY07790.1 - 0.00011 22.5 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Actin PF00022.19 CBY07791.1 - 1.5e-23 83.1 0.1 9.8e-08 31.0 0.0 3.1 1 1 2 3 3 3 3 Actin z-alpha PF02295.17 CBY07792.1 - 0.001 19.1 0.3 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 Adenosine deaminase z-alpha domain TFIIE_alpha PF02002.17 CBY07792.1 - 0.0037 17.1 0.1 0.012 15.4 0.0 2.0 1 1 1 2 2 2 1 TFIIE alpha subunit TrmB PF01978.19 CBY07792.1 - 0.11 12.4 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.11 CBY07793.1 - 6.6e-06 26.1 0.3 0.019 15.0 0.0 2.8 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 CBY07793.1 - 0.00037 20.3 0.1 0.00072 19.4 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 TPK_B1_binding PF04265.14 CBY07793.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain NEXCaM_BD PF16644.5 CBY07793.1 - 0.14 12.4 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin SAP PF02037.27 CBY07794.1 - 2.6e-05 23.8 0.4 5.3e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 SAP domain Kri1 PF05178.12 CBY07794.1 - 0.0035 17.9 1.1 0.0035 17.9 1.1 2.7 3 0 0 3 3 3 1 KRI1-like family ClpB_D2-small PF10431.9 CBY07794.1 - 0.024 14.7 2.9 0.32 11.1 0.7 2.6 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein YqfQ PF14181.6 CBY07794.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.9 3 1 1 4 4 4 0 YqfQ-like protein MerR-DNA-bind PF09278.11 CBY07794.1 - 1.9 9.1 7.0 20 5.8 0.1 3.5 3 0 0 3 3 3 0 MerR, DNA binding COG2 PF06148.11 CBY07794.1 - 2.6 8.1 11.4 1 9.4 4.4 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec34 PF04136.15 CBY07795.1 - 6.8e-44 149.3 4.0 3.5e-43 147.0 4.0 2.3 1 0 0 1 1 1 1 Sec34-like family Ion_trans PF00520.31 CBY07796.1 - 1.2e-09 37.8 11.4 1.5e-09 37.5 11.4 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CBY07796.1 - 2.1e-09 36.6 7.2 2.8e-09 36.2 7.2 1.2 1 0 0 1 1 1 1 Polycystin cation channel TctB PF07331.11 CBY07796.1 - 0.15 12.3 4.9 1 9.7 3.1 2.2 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF2070 PF09843.9 CBY07796.1 - 0.94 7.7 4.1 1.2 7.3 4.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DHHC PF01529.20 CBY07796.1 - 4.2 7.5 9.0 1.2 9.2 0.1 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase FKBP_C PF00254.28 CBY07797.1 - 1e-32 112.3 0.0 1.2e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GTP_EFTU PF00009.27 CBY07798.1 - 8.2e-41 139.7 0.0 9.9e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBY07798.1 - 8.7e-12 45.3 0.0 1.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CBY07798.1 - 1.3e-05 25.3 0.6 0.00043 20.3 0.6 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBY07798.1 - 0.018 14.4 0.0 0.042 13.2 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Roc PF08477.13 CBY07798.1 - 0.12 12.6 0.0 12 6.1 0.0 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CBY07798.1 - 0.17 12.0 0.6 3.5 7.6 0.5 2.2 1 1 1 2 2 2 0 Dynamin family PIN_8 PF18476.1 CBY07799.1 - 0.0082 16.0 2.3 0.33 10.8 0.2 2.1 2 0 0 2 2 2 2 PIN like domain zf-CCCH PF00642.24 CBY07800.1 - 2.5e-08 33.6 2.7 2.5e-08 33.6 2.7 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 CBY07800.1 - 3.6e-06 26.7 10.8 7.6e-06 25.7 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 CBY07800.1 - 3.4e-05 23.7 4.2 9.2e-05 22.4 4.2 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 CBY07800.1 - 4.8e-05 23.1 13.2 0.00011 21.9 13.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY07800.1 - 0.00018 21.6 10.4 0.00044 20.3 10.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CBY07800.1 - 0.00022 21.1 15.0 0.00043 20.2 15.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY07800.1 - 0.00059 19.7 13.9 0.0014 18.4 13.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY07800.1 - 0.00098 19.4 12.5 0.00098 19.4 12.5 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY07800.1 - 0.0022 18.0 11.4 0.0054 16.7 11.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_4 PF18044.1 CBY07800.1 - 0.0025 17.6 2.9 0.0025 17.6 2.9 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 CBY07800.1 - 0.0041 16.9 9.3 0.0081 16.0 9.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 CBY07800.1 - 0.013 15.9 2.9 0.038 14.5 2.9 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-RING_10 PF16685.5 CBY07800.1 - 0.1 12.8 8.7 0.24 11.6 8.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 CBY07800.1 - 0.25 11.0 8.3 0.56 9.9 8.3 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-Nse PF11789.8 CBY07800.1 - 0.76 9.6 7.7 1.7 8.5 7.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RAI16-like PF10257.9 CBY07801.1 - 8.3e-50 169.7 1.4 1.5e-49 168.8 1.4 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein NPR3 PF03666.13 CBY07802.1 - 4.1e-13 48.9 10.2 1.7e-11 43.6 10.3 2.4 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 CBY07802.1 - 0.00095 18.0 0.1 0.0031 16.3 0.0 1.8 2 0 0 2 2 2 1 Nitrogen permease regulator 2 HECW1_helix PF18436.1 CBY07802.1 - 0.059 13.5 0.5 0.66 10.1 0.1 2.7 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Trypsin PF00089.26 CBY07804.1 - 1.6e-44 152.3 0.0 2.6e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trefoil PF00088.18 CBY07804.1 - 3.4e-13 49.3 32.5 1.1e-07 31.6 1.7 4.1 4 0 0 4 4 4 3 Trefoil (P-type) domain TEX29 PF15839.5 CBY07804.1 - 0.22 12.1 12.7 1.7 9.3 0.9 3.6 3 0 0 3 3 3 0 Testis-expressed sequence 29 protein Drc1-Sld2 PF11719.8 CBY07804.1 - 1.6 8.2 7.4 3.1 7.2 7.4 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein Trypsin PF00089.26 CBY07805.1 - 3.3e-58 197.1 0.1 4.3e-49 167.3 0.1 2.1 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CBY07805.1 - 9e-07 29.9 0.0 0.00012 23.0 0.0 2.3 2 0 0 2 2 2 2 Trypsin-like peptidase domain DUF900 PF05990.12 CBY07805.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF5112 PF17139.4 CBY07806.1 - 0.045 13.2 0.1 0.05 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) CtIP_N PF10482.9 CBY07806.1 - 0.078 13.0 0.1 0.15 12.1 0.1 1.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain FAM91_C PF14648.6 CBY07808.1 - 0.0013 17.7 0.0 0.029 13.2 0.0 2.1 1 1 1 2 2 2 2 FAM91 C-terminus FAM91_N PF14647.6 CBY07809.1 - 1.2e-96 323.7 1.5 1.6e-96 323.3 1.5 1.1 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.6 CBY07809.1 - 1.1e-24 87.1 0.6 1.8e-24 86.4 0.3 1.5 1 1 0 1 1 1 1 FAM91 C-terminus Ribosomal_S18 PF01084.20 CBY07811.1 - 1.6e-09 37.9 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Glyco_transf_7N PF13733.6 CBY07812.1 - 5.3e-38 129.7 0.1 8.5e-38 129.0 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY07812.1 - 9e-27 92.6 0.3 2.2e-26 91.3 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PCNA_C PF02747.15 CBY07813.1 - 5.9e-53 178.4 0.0 1.1e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 CBY07813.1 - 5.3e-44 149.0 7.2 9.9e-44 148.1 7.2 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 CBY07813.1 - 1.8e-06 27.3 0.1 4.2e-06 26.0 0.1 1.6 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CBY07813.1 - 0.014 14.8 0.5 0.023 14.2 0.5 1.3 1 1 0 1 1 1 0 Rad9 zf-C4 PF00105.18 CBY07814.1 - 1.3e-23 83.3 11.5 2.6e-23 82.2 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY07814.1 - 2.3e-12 47.0 1.6 2.3e-12 47.0 1.6 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor FOLN PF09289.10 CBY07814.1 - 0.0061 16.7 2.1 0.017 15.3 2.1 1.8 1 0 0 1 1 1 1 Follistatin/Osteonectin-like EGF domain Aminotran_5 PF00266.19 CBY07815.1 - 5.6e-12 45.3 0.0 8.2e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CBY07815.1 - 0.18 10.3 0.0 0.28 9.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme zf-H2C2_2 PF13465.6 CBY07816.1 - 7e-17 61.0 12.2 1.6e-08 34.6 0.5 3.8 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY07816.1 - 1.6e-15 56.6 10.9 1.5e-05 25.2 0.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY07816.1 - 8.2e-13 48.0 10.9 0.0014 19.3 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY07816.1 - 4.8e-07 29.9 3.5 0.18 12.1 0.0 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY07816.1 - 7.1e-05 22.7 13.0 0.3 11.1 3.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY07816.1 - 7.2e-05 23.0 9.3 0.064 13.7 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CBY07816.1 - 0.00054 19.7 2.4 4.4 7.1 0.1 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CBY07816.1 - 0.0042 17.2 5.6 2.5 8.3 0.3 3.5 3 0 0 3 3 3 1 Zinc ribbon domain Attractin PF08037.11 CBY07816.1 - 0.015 15.3 0.6 0.031 14.3 0.6 1.5 1 0 0 1 1 1 0 Attractin family zf-C2HE PF16278.5 CBY07816.1 - 0.047 14.1 10.8 2.7 8.5 0.2 3.6 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 CBY07816.1 - 0.078 13.0 4.2 7.1 6.7 0.2 2.9 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 CBY07816.1 - 0.11 12.8 6.0 2 8.8 1.2 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 CBY07816.1 - 0.12 12.7 0.5 0.28 11.5 0.5 1.6 1 0 0 1 1 1 0 zinc-finger-containing domain Prok-RING_1 PF14446.6 CBY07816.1 - 0.16 11.9 4.0 32 4.5 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 CBY07816.1 - 0.16 11.8 5.8 5.1 7.1 0.5 2.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-AN1 PF01428.16 CBY07816.1 - 0.21 11.8 5.5 22 5.3 0.2 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger zf-Di19 PF05605.12 CBY07816.1 - 0.31 11.4 6.3 1.1 9.6 1.5 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2180 PF09947.9 CBY07816.1 - 0.38 10.7 2.5 1.9 8.5 1.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) ADK_lid PF05191.14 CBY07816.1 - 0.52 10.3 4.0 0.24 11.4 0.9 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid DZR PF12773.7 CBY07816.1 - 0.54 10.3 4.3 6.2 6.9 4.3 2.5 1 1 0 1 1 1 0 Double zinc ribbon PyrI_C PF02748.15 CBY07816.1 - 0.73 9.8 3.2 6.6 6.7 0.2 2.9 1 1 2 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_2 PF03107.16 CBY07816.1 - 0.88 9.9 6.9 27 5.2 0.2 3.1 1 1 1 2 2 2 0 C1 domain zf-C2HC_2 PF13913.6 CBY07816.1 - 0.97 9.4 9.3 3.2 7.8 0.2 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-CCHC_2 PF13696.6 CBY07816.1 - 1 9.2 5.0 0.61 10.0 1.7 2.3 2 0 0 2 2 2 0 Zinc knuckle HNH PF01844.23 CBY07816.1 - 1.1 9.5 8.9 5.5 7.2 0.2 3.7 3 0 0 3 3 3 0 HNH endonuclease Zn_Tnp_IS1595 PF12760.7 CBY07816.1 - 1.3 9.0 4.2 0.81 9.7 1.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf_UBZ PF18439.1 CBY07816.1 - 1.8 8.2 4.7 5 6.8 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 CBY07816.1 - 2.6 8.9 5.7 3.3 8.5 1.6 2.5 2 1 1 3 3 2 0 zinc-ribbon family Zn_ribbon_SprT PF17283.2 CBY07816.1 - 3.6 7.6 8.0 2.3 8.2 0.9 3.1 3 1 0 3 3 2 0 SprT-like zinc ribbon domain MRP-L51 PF10244.9 CBY07817.1 - 2.9e-05 24.2 0.4 8.7e-05 22.7 0.4 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit HIP1_clath_bdg PF16515.5 CBY07818.1 - 0.013 16.1 0.8 0.065 13.8 0.8 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4110 PF13422.6 CBY07818.1 - 0.015 15.4 1.9 0.073 13.1 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Pkinase_Tyr PF07714.17 CBY07819.1 - 5.6e-64 215.9 0.0 8.7e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY07819.1 - 5.1e-29 101.5 0.0 6.3e-28 97.9 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Syndecan PF01034.20 CBY07819.1 - 0.00072 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.10 CBY07819.1 - 0.018 14.4 2.7 0.034 13.5 2.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kinase-like PF14531.6 CBY07819.1 - 0.03 13.6 0.0 0.082 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like 7TM_GPCR_Srd PF10317.9 CBY07819.1 - 0.11 11.6 0.1 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd FMN_red PF03358.15 CBY07821.1 - 1.3e-23 83.5 0.0 1.5e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CBY07821.1 - 3.8e-06 26.8 0.0 2.1e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Flavodoxin-like fold TatD_DNase PF01026.21 CBY07822.1 - 2.2e-48 164.9 0.0 2.5e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Pkinase PF00069.25 CBY07823.1 - 1.3e-46 159.1 0.0 1.9e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY07823.1 - 6.3e-19 68.3 0.0 9.7e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBY07823.1 - 0.085 12.5 0.0 5.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cofilin_ADF PF00241.20 CBY07824.1 - 1.9e-28 98.7 0.1 2.3e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RRM_1 PF00076.22 CBY07825.1 - 5.6e-27 93.4 0.3 1.9e-16 59.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY07825.1 - 2.7e-08 33.8 0.0 2.6e-05 24.3 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CBY07825.1 - 0.0001 22.2 0.1 0.6 10.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 CBY07825.1 - 0.0041 17.0 0.3 1.8 8.6 0.0 2.8 3 0 0 3 3 3 2 RL domain MIF PF01187.18 CBY07825.1 - 0.077 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) SVIP PF15811.5 CBY07825.1 - 0.14 12.6 1.0 0.29 11.6 1.0 1.5 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Polyketide_cyc PF03364.20 CBY07826.1 - 8.3e-11 42.2 0.0 1.1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport WLM PF08325.10 CBY07827.1 - 0.51 10.4 2.8 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 WLM domain COG5 PF10392.9 CBY07828.1 - 1.1e-22 80.6 7.1 1.1e-22 80.6 7.1 4.0 5 1 1 6 6 6 1 Golgi transport complex subunit 5 Vps51 PF08700.11 CBY07828.1 - 5e-06 26.5 1.7 5e-06 26.5 1.7 2.6 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 CBY07828.1 - 0.012 15.7 4.3 0.012 15.7 4.3 3.4 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Spore_GerAC PF05504.11 CBY07828.1 - 0.027 14.7 0.4 0.027 14.7 0.4 3.8 4 1 0 4 4 4 0 Spore germination B3/ GerAC like, C-terminal GTP-bdg_N PF13167.6 CBY07828.1 - 0.053 14.2 0.4 0.48 11.1 0.2 2.8 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal eIF-5_eIF-2B PF01873.17 CBY07828.1 - 0.055 13.4 0.7 17 5.3 0.1 3.3 2 1 0 2 2 2 0 Domain found in IF2B/IF5 UCR_14kD PF02271.16 CBY07828.1 - 0.059 13.3 0.5 0.28 11.2 0.0 2.4 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DnaJ PF00226.31 CBY07829.1 - 8.6e-12 45.0 0.4 8.6e-12 45.0 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain Lactate_perm PF02652.14 CBY07829.1 - 0.15 10.7 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 L-lactate permease Bud13 PF09736.9 CBY07830.1 - 1e-41 142.7 14.6 1e-41 142.7 14.6 3.4 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex BolA PF01722.18 CBY07831.1 - 3.1e-12 46.6 0.0 4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein DinI PF06183.13 CBY07831.1 - 0.034 14.5 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 DinI-like family YccV-like PF08755.11 CBY07832.1 - 0.031 14.8 0.0 0.039 14.5 0.0 1.2 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like Pilt PF15453.6 CBY07833.1 - 0.092 12.1 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Connexin PF00029.19 CBY07836.1 - 1.1e-07 31.8 2.9 2.5e-06 27.4 2.9 2.5 1 1 0 1 1 1 1 Connexin DUF3755 PF12579.8 CBY07836.1 - 0.24 11.1 1.5 0.46 10.2 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Pro_dh PF01619.18 CBY07838.1 - 9e-80 268.4 0.0 7.9e-79 265.3 0.0 2.3 1 1 1 2 2 2 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 CBY07838.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel An_peroxidase PF03098.15 CBY07839.1 - 3.1e-100 336.3 0.8 4e-100 335.9 0.8 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Aldedh PF00171.22 CBY07840.1 - 2.2e-148 494.6 0.1 2.7e-148 494.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CBY07840.1 - 0.00038 20.0 0.3 0.0021 17.6 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) zf-C3HC4_3 PF13920.6 CBY07841.1 - 6.1e-17 61.2 7.4 1.3e-16 60.1 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY07841.1 - 1.1e-09 38.0 7.8 2.6e-09 36.8 7.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY07841.1 - 7.1e-08 32.7 9.1 2.8e-07 30.7 9.1 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY07841.1 - 0.00017 21.4 9.0 0.00046 20.0 9.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY07841.1 - 0.00019 21.3 7.2 0.00066 19.6 7.2 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 CBY07841.1 - 0.0055 16.5 7.7 0.0055 16.5 7.7 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CBY07841.1 - 0.22 11.6 6.9 3.3 7.8 2.0 2.6 2 0 0 2 2 2 0 RING-type zinc-finger MRI PF15325.6 CBY07841.1 - 1.1 10.4 9.0 6.6 7.9 9.0 2.3 1 0 0 1 1 1 0 Modulator of retrovirus infection Chitin_synth_2 PF03142.15 CBY07843.1 - 9.7e-32 110.3 1.1 1.1e-26 93.5 0.1 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CBY07843.1 - 6.9e-11 42.4 5.3 1.6e-10 41.3 5.3 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CBY07843.1 - 9.7e-10 38.7 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CBY07843.1 - 0.00048 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CBY07843.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 21 ZT_dimer PF16916.5 CBY07843.1 - 0.12 12.5 0.1 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter Proteasome PF00227.26 CBY07844.1 - 3.8e-42 143.9 0.6 4.4e-42 143.7 0.6 1.0 1 0 0 1 1 1 1 Proteasome subunit APG9 PF04109.16 CBY07845.1 - 5.5e-147 490.6 16.8 6.6e-147 490.4 16.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 adh_short PF00106.25 CBY07846.1 - 1.5e-38 132.3 1.5 1.8e-38 132.0 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY07846.1 - 2.3e-33 115.7 0.1 3.3e-33 115.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY07846.1 - 6.1e-10 39.3 0.1 1e-09 38.6 0.1 1.3 1 1 0 1 1 1 1 KR domain STALD PF18185.1 CBY07846.1 - 0.1 11.9 1.0 0.2 10.9 1.0 1.5 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family FAM47 PF14642.6 CBY07847.1 - 7.5e-12 45.3 0.3 9.9e-12 44.9 0.3 1.0 1 0 0 1 1 1 1 FAM47 family Pkinase PF00069.25 CBY07849.1 - 4.9e-76 255.6 0.0 8.2e-76 254.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY07849.1 - 2.1e-46 158.3 0.0 3.2e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CBY07849.1 - 2.1e-18 66.4 0.1 5.3e-18 65.1 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CBY07849.1 - 4.1e-06 26.3 0.0 3.9e-05 23.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBY07849.1 - 4.2e-06 25.8 1.2 4.3e-05 22.5 1.2 2.1 1 1 0 1 1 1 1 Fungal protein kinase DSHCT PF08148.12 CBY07849.1 - 0.00069 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain APH PF01636.23 CBY07849.1 - 0.0089 16.0 0.1 0.32 10.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Dscam_C PF12355.8 CBY07849.1 - 6.9 7.7 11.3 0.11 13.5 2.8 2.3 2 1 1 3 3 3 0 Down syndrome cell adhesion molecule C terminal Pedibin PF08182.11 CBY07850.1 - 4.8e-19 67.8 2.2 4.8e-19 67.8 2.2 3.6 2 0 0 2 2 2 1 Pedibin/Hym-346 family HSBP1 PF06825.12 CBY07850.1 - 0.05 13.5 10.9 30 4.6 0.3 6.2 4 1 1 5 5 5 0 Heat shock factor binding protein 1 Stealth_CR3 PF17102.5 CBY07850.1 - 0.51 10.3 2.9 5.4 7.0 0.4 2.7 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 PACT_coil_coil PF10495.9 CBY07851.1 - 1.6e-19 70.2 0.0 1.6e-19 70.2 0.0 5.5 5 0 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_DNA_bd PF12329.8 CBY07851.1 - 0.0062 16.5 9.9 0.0062 16.5 9.9 21.4 13 6 8 22 22 22 4 TATA element modulatory factor 1 DNA binding NIPSNAP PF07978.13 CBY07852.1 - 9.7e-22 77.1 0.1 2.8e-19 69.2 0.0 2.8 2 1 0 2 2 2 2 NIPSNAP zf-C3HC4_3 PF13920.6 CBY07853.1 - 5.6e-08 32.5 10.6 8.6e-08 31.9 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SPA PF08616.10 CBY07853.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis zf-RING_2 PF13639.6 CBY07853.1 - 0.94 9.9 13.1 1.7 9.0 13.1 1.4 1 0 0 1 1 1 0 Ring finger domain Mesd PF10185.9 CBY07854.1 - 7.6e-14 51.9 2.5 1.1e-13 51.5 2.3 1.3 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor LTV PF04180.14 CBY07857.1 - 2.8e-51 175.5 33.3 5.2e-51 174.6 33.3 1.4 1 1 0 1 1 1 1 Low temperature viability protein Ntox15 PF15604.6 CBY07857.1 - 0.025 14.7 8.7 0.085 13.0 8.7 1.9 1 0 0 1 1 1 0 Novel toxin 15 DUF5568 PF17724.1 CBY07857.1 - 0.45 10.3 3.0 0.92 9.3 3.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5568) Peptidase_S49_N PF08496.10 CBY07857.1 - 1.4 9.0 11.4 3.3 7.7 11.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal His_Phos_2 PF00328.22 CBY07858.1 - 9.4e-07 28.5 0.0 9.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ATG7_N PF16420.5 CBY07858.1 - 0.045 13.4 0.5 0.13 11.8 0.4 1.7 2 0 0 2 2 2 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus DSPc PF00782.20 CBY07859.1 - 6.6e-40 136.0 0.0 9.8e-40 135.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 CBY07859.1 - 6.7e-07 29.8 0.0 1.5e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 CBY07859.1 - 2.8e-06 27.1 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CBY07859.1 - 0.0049 17.1 0.0 0.017 15.4 0.0 1.9 2 1 0 2 2 2 1 Rit1 DUSP-like domain Myotub-related PF06602.14 CBY07859.1 - 0.065 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 CBY07859.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF442 PF04273.13 CBY07859.1 - 0.21 11.7 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) AzlD PF05437.12 CBY07860.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) Multi_Drug_Res PF00893.19 CBY07860.1 - 0.083 13.6 0.0 0.22 12.2 0.0 1.6 2 0 0 2 2 2 0 Small Multidrug Resistance protein Ion_trans PF00520.31 CBY07861.1 - 9.6e-22 77.4 0.3 1.2e-21 77.1 0.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY07861.1 - 2.9e-11 43.2 4.1 2.9e-11 43.2 4.1 2.0 2 1 1 3 3 3 1 Ion channel DUF3854 PF12965.7 CBY07861.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) COesterase PF00135.28 CBY07862.1 - 8.2e-59 199.8 0.0 1.3e-58 199.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY07862.1 - 3.9e-07 30.2 0.1 2.4e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_transf_8 PF01501.20 CBY07862.1 - 6.4e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Esterase PF00756.20 CBY07862.1 - 0.074 12.7 0.1 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative esterase PAE PF03283.13 CBY07862.1 - 0.1 11.7 0.0 0.9 8.6 0.0 2.2 3 0 0 3 3 3 0 Pectinacetylesterase E1_DerP2_DerF2 PF02221.15 CBY07863.1 - 0.12 12.8 3.3 0.08 13.4 1.0 1.9 2 0 0 2 2 2 0 ML domain Glyco_hydro_9 PF00759.19 CBY07864.1 - 1.6e-128 429.7 3.1 2.3e-128 429.1 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 NBP1 PF08537.10 CBY07864.1 - 0.088 12.2 6.6 0.19 11.1 6.6 1.5 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF16 PF01519.16 CBY07864.1 - 0.15 12.6 8.7 0.26 11.8 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 CBY07864.1 - 0.54 9.8 6.4 0.95 9.0 6.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 CBY07864.1 - 0.79 9.8 12.4 14 5.7 11.2 2.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 CBY07864.1 - 1.7 8.7 11.6 3.3 7.8 11.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF5580 PF17743.1 CBY07865.1 - 0.011 14.4 0.0 0.011 14.3 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_11 PF08976.11 CBY07865.1 - 0.052 14.4 0.1 0.076 13.9 0.1 1.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 CBY07865.1 - 0.081 13.4 0.1 1.1 9.8 0.0 2.3 1 1 0 2 2 2 0 EF-hand domain pair DDE_Tnp_ISAZ013 PF07592.11 CBY07865.1 - 0.086 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain EF-hand_1 PF00036.32 CBY07865.1 - 0.22 11.1 1.7 11 5.9 0.0 3.1 4 0 0 4 4 4 0 EF hand 3HCDH_N PF02737.18 CBY07867.1 - 5e-53 179.7 0.1 8.9e-53 178.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 CBY07867.1 - 7.7e-37 126.9 0.5 2.6e-36 125.2 0.5 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 CBY07867.1 - 9.1e-25 87.1 0.0 3.7e-18 65.9 0.0 3.7 4 0 0 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 CBY07867.1 - 5.9e-21 75.3 0.2 9.2e-21 74.7 0.2 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 CBY07867.1 - 0.063 13.4 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UbiA PF01040.18 CBY07868.1 - 0.026 13.8 3.6 0.038 13.3 3.6 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF4199 PF13858.6 CBY07868.1 - 0.11 12.9 7.4 0.036 14.5 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Myosin_head PF00063.21 CBY07869.1 - 3.2e-287 954.3 1.0 1e-286 952.6 1.0 2.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY07869.1 - 2.3e-251 837.0 287.4 3.1e-251 836.6 287.4 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY07869.1 - 5.9e-05 22.8 1.9 8.8e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain DUF641 PF04859.12 CBY07869.1 - 0.00073 19.9 9.7 0.00073 19.9 9.7 13.6 2 2 11 13 13 13 1 Plant protein of unknown function (DUF641) IQ PF00612.27 CBY07869.1 - 0.0032 17.1 0.8 0.011 15.5 0.1 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY07869.1 - 0.026 14.8 0.0 0.026 14.8 0.0 6.1 6 1 0 6 6 6 0 AAA domain MtrB PF05440.12 CBY07869.1 - 0.32 11.4 1.3 5.6 7.5 0.1 3.9 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Tropomyosin_1 PF12718.7 CBY07871.1 - 0.0077 16.4 13.5 0.01 16.0 13.5 1.2 1 0 0 1 1 1 1 Tropomyosin like CCDC53 PF10152.9 CBY07871.1 - 0.03 14.8 3.1 0.041 14.3 3.1 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Raf1_HTH PF18579.1 CBY07871.1 - 0.044 13.5 5.7 16 5.3 5.7 2.2 1 1 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Mt_ATP-synt_D PF05873.12 CBY07871.1 - 0.045 13.6 9.5 0.14 12.0 9.3 1.7 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Laminin_II PF06009.12 CBY07871.1 - 0.24 11.4 10.1 0.38 10.8 4.7 2.2 2 1 0 2 2 2 0 Laminin Domain II V_ATPase_I PF01496.19 CBY07871.1 - 0.33 8.8 6.7 0.37 8.6 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 CBY07871.1 - 0.91 9.7 9.5 8.4 6.6 6.9 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PCRF PF03462.18 CBY07871.1 - 1.4 8.8 12.0 1.5 8.6 11.1 1.5 1 1 1 2 2 2 0 PCRF domain UPF0242 PF06785.11 CBY07871.1 - 1.5 8.9 15.7 2.5 8.2 15.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CBY07871.1 - 3 7.3 10.3 3.5 7.1 10.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 CBY07871.1 - 3.1 6.8 15.5 3.7 6.5 15.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 CBY07871.1 - 3.5 6.8 10.3 4.2 6.5 10.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein FlxA PF14282.6 CBY07871.1 - 5.9 6.9 16.8 3.6 7.6 14.8 1.6 1 1 1 2 2 2 0 FlxA-like protein XhlA PF10779.9 CBY07871.1 - 6.6 7.0 9.9 2.2 8.6 3.5 2.7 1 1 1 2 2 2 0 Haemolysin XhlA FapA PF03961.13 CBY07871.1 - 7.1 5.1 10.2 8.3 4.9 10.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 CBY07871.1 - 7.8 5.2 9.7 9.2 5.0 9.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Med9 PF07544.13 CBY07871.1 - 8.8 6.5 14.2 3 8.0 9.8 2.4 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 7tm_1 PF00001.21 CBY07872.1 - 2.3e-17 63.2 6.9 3e-17 62.8 6.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3810 PF12725.7 CBY07872.1 - 0.041 13.2 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Bac_export_2 PF01312.19 CBY07872.1 - 0.17 11.1 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Cyt_bd_oxida_II PF02322.15 CBY07872.1 - 0.2 11.0 3.3 7.3 5.9 0.1 2.1 1 1 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II Pox_EPC_I2-L1 PF12575.8 CBY07872.1 - 1.1 9.6 6.5 11 6.3 0.6 3.1 3 1 1 4 4 4 0 Poxvirus entry protein complex L1 and I2 Sulfate_transp PF00916.20 CBY07873.1 - 1.1e-12 47.4 0.2 1.2e-12 47.3 0.2 1.0 1 0 0 1 1 1 1 Sulfate permease family Sulfate_transp PF00916.20 CBY07874.1 - 5.1e-17 61.7 7.1 1.5e-15 56.9 7.1 2.7 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CBY07874.1 - 9.8e-10 38.1 0.1 7.6e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 CBY07874.1 - 0.094 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 STAS domain DUF3021 PF11457.8 CBY07874.1 - 0.11 12.9 5.2 0.32 11.3 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF4013 PF13197.6 CBY07874.1 - 1.8 8.3 12.8 5 6.9 12.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) MFS_1 PF07690.16 CBY07875.1 - 2.9e-32 112.0 26.6 2.9e-32 112.0 26.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1240 PF06836.12 CBY07875.1 - 0.043 14.4 0.1 17 6.0 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1240) LRR_4 PF12799.7 CBY07876.1 - 4.7e-11 42.7 8.9 2.3e-07 31.0 2.2 3.7 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY07876.1 - 1.2e-10 41.2 0.9 2.2e-10 40.3 0.8 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBY07876.1 - 9.5e-10 38.1 17.9 6.7e-06 25.8 4.3 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 CBY07876.1 - 0.00086 19.5 8.1 2.6 8.9 0.5 4.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY07876.1 - 0.054 13.6 0.8 13 6.2 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat ANAPC4_WD40 PF12894.7 CBY07877.1 - 0.00012 22.3 0.0 0.00056 20.2 0.0 2.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain NT5C PF06941.12 CBY07878.1 - 7.6e-19 68.3 0.1 1.1e-18 67.7 0.1 1.2 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF2673 PF10880.8 CBY07878.1 - 0.11 12.7 0.3 0.23 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) SRP40_C PF05022.12 CBY07879.1 - 1.4e-23 83.5 2.2 1.4e-23 83.5 2.2 2.4 2 0 0 2 2 2 1 SRP40, C-terminal domain CDK5_activator PF03261.15 CBY07880.1 - 9.6e-21 74.7 0.3 1.4e-20 74.2 0.3 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein CDK5_activator PF03261.15 CBY07881.1 - 1.3e-15 57.9 0.1 1.5e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein HEAT PF02985.22 CBY07882.1 - 6.7e-11 41.5 5.3 0.058 13.7 0.0 8.0 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 CBY07882.1 - 0.00028 21.2 1.3 5.8 7.4 0.0 6.3 6 0 0 6 6 6 1 HEAT repeats Ipi1_N PF12333.8 CBY07882.1 - 0.0011 19.5 1.5 4.8 7.8 0.0 4.9 5 0 0 5 5 5 2 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.23 CBY07882.1 - 0.0024 17.9 2.0 0.21 11.7 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CBY07882.1 - 0.0051 17.4 0.1 0.14 12.8 0.0 3.4 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 CBY07882.1 - 0.032 14.5 0.1 2.9 8.3 0.0 3.8 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 CBY07882.1 - 0.17 12.5 6.4 81 3.9 0.3 6.4 7 0 0 7 7 7 0 HEAT-like repeat EF-hand_7 PF13499.6 CBY07883.1 - 2e-10 40.9 0.4 6.2e-10 39.4 0.4 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_13 PF17958.1 CBY07883.1 - 4.7e-08 32.7 0.0 1.5e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.6 CBY07883.1 - 0.00026 20.7 0.1 0.0025 17.6 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBY07883.1 - 0.0077 15.7 0.0 0.025 14.0 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CBY07883.1 - 0.055 13.0 0.1 0.055 13.0 0.1 2.4 2 0 0 2 2 2 0 EF hand RCDG1 PF15725.5 CBY07883.1 - 2 8.9 4.5 0.81 10.2 1.5 1.9 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein UDG PF03167.19 CBY07884.1 - 9.8e-25 87.3 0.0 1.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Zona_pellucida PF00100.23 CBY07885.1 - 5e-44 151.0 1.0 6.1e-44 150.7 1.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Sulfatase PF00884.23 CBY07886.1 - 1.6e-50 172.3 0.5 2e-50 171.9 0.5 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY07886.1 - 1.8e-06 27.8 2.4 5.8e-06 26.1 2.3 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CBY07886.1 - 0.0027 16.4 4.7 0.16 10.5 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF229) ADH_N PF08240.12 CBY07888.1 - 1.1e-22 80.0 2.5 1.3e-22 79.7 1.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBY07888.1 - 3.2e-15 56.3 0.0 7.2e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBY07888.1 - 1.4e-12 47.6 0.4 6.1e-12 45.5 0.4 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CBY07888.1 - 0.0045 16.3 0.1 0.0078 15.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 CBY07888.1 - 0.006 15.9 0.1 0.24 10.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase YdfZ PF14001.6 CBY07888.1 - 0.063 13.7 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 YdfZ protein PAGK PF15284.6 CBY07888.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage-encoded virulence factor Thioredoxin PF00085.20 CBY07889.1 - 2.6e-05 24.1 0.0 2.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 CBY07890.1 - 7.6e-10 38.7 0.0 4.1e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CBY07890.1 - 0.073 13.5 0.1 13 6.2 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain TraF PF13728.6 CBY07890.1 - 0.088 12.6 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 F plasmid transfer operon protein Spy1 PF11357.8 CBY07891.1 - 2.2e-08 34.5 0.3 3.6e-08 33.8 0.3 1.3 1 0 0 1 1 1 1 Cell cycle regulatory protein PG_binding_4 PF12229.8 CBY07891.1 - 0.12 12.6 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Collagen PF01391.18 CBY07892.1 - 3.8e-47 157.9 166.6 6.8e-09 35.4 26.4 6.7 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY07892.1 - 7.3e-09 36.1 0.0 1e-08 35.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY07892.1 - 2.7e-05 24.8 0.0 4.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Sensor_TM1 PF13755.6 CBY07895.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.4 3 1 0 3 3 3 0 Sensor N-terminal transmembrane domain Pro_isomerase PF00160.21 CBY07896.1 - 1.2e-07 32.1 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA_24 PF13479.6 CBY07896.1 - 0.0035 17.1 0.1 0.0067 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain DUF4810 PF16068.5 CBY07896.1 - 0.047 14.2 0.1 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) Prefoldin_2 PF01920.20 CBY07896.1 - 0.13 12.2 0.4 0.2 11.7 0.4 1.2 1 0 0 1 1 1 0 Prefoldin subunit FAM110_C PF14160.6 CBY07897.1 - 4.1e-06 27.9 0.7 2.5e-05 25.3 0.0 2.4 1 1 1 2 2 2 1 Centrosome-associated C terminus FAM110_N PF14161.6 CBY07897.1 - 0.00032 20.9 5.1 0.00076 19.7 5.1 1.8 1 1 0 1 1 1 1 Centrosome-associated N terminus cwf21 PF08312.12 CBY07898.1 - 3.1e-14 52.9 3.6 3.1e-14 52.9 3.6 3.3 3 1 0 3 3 3 1 cwf21 domain TQ PF18202.1 CBY07898.1 - 1.7 9.2 7.4 0.15 12.6 2.4 1.7 2 0 0 2 2 2 0 T-Q ester bond containing domain RRM_1 PF00076.22 CBY07899.1 - 2.4e-07 30.5 0.0 1.8e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY07899.1 - 0.044 13.9 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 CBY07900.1 - 1.2e-38 130.8 0.2 2.1e-19 69.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY07900.1 - 1.4e-09 37.6 0.0 0.00042 19.9 0.1 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBY07900.1 - 0.016 15.3 0.4 0.43 10.7 0.0 2.5 1 1 1 2 2 2 0 Limkain b1 RRM_3 PF08777.11 CBY07900.1 - 0.076 13.1 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Ribosomal_L38e PF01781.18 CBY07901.1 - 1.2e-35 121.4 2.8 1.3e-35 121.3 2.8 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Nop16 PF09420.10 CBY07902.1 - 2.8e-16 60.2 12.1 2.8e-11 43.8 3.3 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 ATS PF15445.6 CBY07902.1 - 0.011 15.2 0.4 0.012 15.0 0.4 1.0 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 Zona_pellucida PF00100.23 CBY07903.1 - 1.1e-12 48.3 2.5 1.7e-12 47.7 2.5 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain EGF_3 PF12947.7 CBY07903.1 - 0.012 15.8 5.9 0.012 15.8 5.9 2.2 2 0 0 2 2 2 0 EGF domain hEGF PF12661.7 CBY07903.1 - 0.037 14.7 3.9 0.23 12.1 3.9 2.5 1 0 0 1 1 1 0 Human growth factor-like EGF DUF5050 PF16472.5 CBY07903.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) EGF PF00008.27 CBY07903.1 - 0.1 12.9 6.2 0.074 13.4 4.1 2.1 1 1 0 1 1 1 0 EGF-like domain CUB PF00431.20 CBY07904.1 - 6.7e-11 42.5 0.0 8.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 CUB domain Complex1_51K PF01512.17 CBY07904.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Gal-3-0_sulfotr PF06990.11 CBY07905.1 - 9.4e-22 77.4 1.2 7.6e-15 54.7 0.4 2.1 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Peptidase_C97 PF05903.14 CBY07906.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain Mito_fiss_reg PF05308.11 CBY07906.1 - 0.13 12.3 0.6 0.17 12.0 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Dicty_REP PF05086.12 CBY07908.1 - 0.016 13.2 9.4 0.016 13.2 9.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.11 CBY07908.1 - 3 7.7 13.3 4.2 7.3 13.3 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.17 CBY07908.1 - 5.4 7.0 33.4 7.6 6.5 33.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 CBY07908.1 - 8.7 4.3 11.5 9.4 4.2 11.5 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1143 PF06608.11 CBY07909.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) Gal-3-0_sulfotr PF06990.11 CBY07910.1 - 7.2e-35 120.6 0.5 1.1e-32 113.4 0.5 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Trypsin PF00089.26 CBY07911.1 - 1.1e-14 54.8 0.9 1.2e-14 54.6 0.9 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CBY07912.1 - 2.3e-16 60.3 0.1 2.6e-14 53.6 0.1 2.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY07912.1 - 0.012 16.5 0.0 0.035 15.0 0.0 1.7 1 1 0 1 1 1 0 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY07912.1 - 0.044 14.2 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) DUF5052 PF16475.5 CBY07913.1 - 0.028 14.0 0.0 0.032 13.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) Glyco_hydro_18 PF00704.28 CBY07916.1 - 2.5e-70 237.7 9.8 3.2e-70 237.4 9.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 CBY07916.1 - 1.2e-11 44.5 9.9 1.2e-11 44.5 9.9 1.9 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Ank_2 PF12796.7 CBY07917.1 - 5.9e-07 30.0 0.0 0.0093 16.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY07917.1 - 2.8e-06 27.8 0.0 0.046 14.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY07917.1 - 0.0077 16.5 0.0 0.77 10.2 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY07917.1 - 0.036 14.6 0.0 0.16 12.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 CBY07918.1 - 1.4e-30 105.7 1.4 6.2e-11 42.7 0.0 4.3 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY07918.1 - 4.4e-30 100.4 3.3 8.7e-06 25.7 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 CBY07918.1 - 1e-28 99.3 1.5 3.7e-08 33.8 0.1 5.7 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY07918.1 - 1.6e-27 94.7 5.0 7.1e-07 29.4 0.1 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 CBY07918.1 - 1.9e-19 69.5 4.6 2.8e-07 30.7 0.2 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 CBY07918.1 - 0.012 15.5 0.0 0.056 13.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) eIF_4EBP PF05456.11 CBY07919.1 - 5e-26 90.9 0.4 5.8e-26 90.7 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) MAPEG PF01124.18 CBY07920.1 - 3.1e-23 82.1 1.3 3.6e-23 81.9 1.3 1.1 1 0 0 1 1 1 1 MAPEG family CS PF04969.16 CBY07921.1 - 2.5e-06 28.4 0.1 4.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 CS domain TOM20_plant PF06552.12 CBY07921.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 CcmE PF03100.15 CBY07921.1 - 0.12 12.4 0.6 0.86 9.6 0.1 2.3 2 1 1 3 3 3 0 CcmE NOA36 PF06524.12 CBY07921.1 - 0.2 10.9 5.0 0.33 10.3 5.0 1.3 1 0 0 1 1 1 0 NOA36 protein CelD_N PF02927.14 CBY07921.1 - 0.76 10.7 2.8 0.83 10.6 0.4 2.3 2 1 0 2 2 2 0 Cellulase N-terminal ig-like domain Vps16_C PF04840.12 CBY07922.1 - 2.2e-09 36.8 1.7 3.7e-09 36.1 1.7 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region LolA PF03548.15 CBY07922.1 - 0.008 15.9 0.1 0.025 14.3 0.1 1.9 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA FlxA PF14282.6 CBY07922.1 - 0.32 11.0 2.9 34 4.5 3.3 2.6 2 0 0 2 2 2 0 FlxA-like protein OST3_OST6 PF04756.13 CBY07923.1 - 6.3e-06 25.7 0.6 7.6e-06 25.5 0.6 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DDRGK PF09756.9 CBY07924.1 - 0.038 13.6 6.3 0.043 13.4 6.3 1.1 1 0 0 1 1 1 0 DDRGK domain GlutR_dimer PF00745.20 CBY07924.1 - 0.35 11.3 7.3 0.59 10.6 7.3 1.4 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain RNA_polI_A14 PF08203.11 CBY07925.1 - 0.31 11.8 2.5 0.68 10.7 1.5 1.9 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Ig_3 PF13927.6 CBY07926.1 - 0.00026 21.5 0.1 1.2 9.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY07926.1 - 0.0024 17.9 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 CBY07926.1 - 0.025 14.8 0.0 0.77 10.0 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain ERCC3_RAD25_C PF16203.5 CBY07927.1 - 1.5e-119 397.7 0.0 2.7e-119 396.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CBY07927.1 - 6.2e-36 123.4 0.0 1.7e-35 121.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY07927.1 - 1.2e-19 71.0 0.0 2.4e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBY07927.1 - 6.4e-10 39.4 0.6 1.4e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CBY07927.1 - 1e-07 31.0 0.0 1.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CBY07927.1 - 8.2e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 CBY07927.1 - 0.003 16.5 0.1 0.0052 15.7 0.1 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 AAA_30 PF13604.6 CBY07927.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Tyr_Deacylase PF02580.16 CBY07928.1 - 6.5e-29 101.3 0.0 7.3e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase NopRA1 PF16201.5 CBY07930.1 - 0.1 12.2 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 RasGEF_N_2 PF14663.6 CBY07930.1 - 0.13 12.7 0.1 0.25 11.7 0.0 1.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Voldacs PF03517.13 CBY07931.1 - 5.8e-13 49.2 5.5 7e-13 48.9 0.6 2.6 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling DnaJ_C PF01556.18 CBY07932.1 - 1.1e-31 109.9 0.1 1.5e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBY07932.1 - 8.4e-21 73.9 5.9 8.4e-21 73.9 5.9 2.2 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBY07932.1 - 6.6e-08 32.8 16.1 1.3e-07 31.8 16.1 1.5 1 0 0 1 1 1 1 DnaJ central domain RPT PF13446.6 CBY07932.1 - 0.025 14.5 0.2 0.098 12.6 0.1 1.9 1 1 1 2 2 2 0 A repeated domain in UCH-protein WSS_VP PF12175.8 CBY07932.1 - 0.086 12.3 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP Cytochrome_C7 PF14522.6 CBY07932.1 - 0.35 10.9 12.6 2.6 8.1 13.2 2.1 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Anti-TRAP PF15777.5 CBY07932.1 - 0.72 9.9 6.4 10 6.2 0.7 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrom_c3_2 PF14537.6 CBY07932.1 - 1.3 9.5 11.8 5.9 7.4 11.8 2.1 1 1 0 1 1 1 0 Cytochrome c3 zf-RING_10 PF16685.5 CBY07932.1 - 4.7 7.4 8.2 6.3 7.0 6.1 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 SLD5_C PF16922.5 CBY07933.1 - 0.0066 16.6 0.0 0.015 15.4 0.0 1.6 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Prim-Pol PF09250.11 CBY07933.1 - 0.1 12.9 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal C1_4 PF07975.12 CBY07935.1 - 0.002 18.3 3.1 0.17 12.2 0.3 2.5 2 0 0 2 2 2 2 TFIIH C1-like domain zf-C2H2_4 PF13894.6 CBY07935.1 - 0.054 14.4 0.9 0.054 14.4 0.9 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Ima1_N PF09779.9 CBY07935.1 - 5.9 7.8 7.9 60 4.5 7.9 2.1 1 1 0 1 1 1 0 Ima1 N-terminal domain XPG_I PF00867.18 CBY07936.1 - 9.9e-10 38.6 1.2 1.7e-09 37.9 0.2 1.9 2 0 0 2 2 2 1 XPG I-region Tox-REase-7 PF15649.6 CBY07936.1 - 0.086 13.2 0.7 0.33 11.3 0.1 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 XPG_N PF00752.17 CBY07937.1 - 4e-13 49.7 0.0 5.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain XRN_N PF03159.18 CBY07937.1 - 0.014 14.9 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Vps52 PF04129.12 CBY07938.1 - 9.2e-152 506.3 16.9 9.2e-152 506.3 16.9 1.7 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.9 CBY07938.1 - 2.5e-09 36.1 16.5 5.9e-09 34.9 16.1 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 Imm25 PF15564.6 CBY07938.1 - 0.057 13.3 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 25 ApoB100_C PF12491.8 CBY07938.1 - 1.1 9.2 8.2 0.35 10.9 0.5 3.9 4 0 0 4 4 4 0 Apolipoprotein B100 C terminal OmpH PF03938.14 CBY07938.1 - 1.2 9.5 7.1 0.42 10.9 0.1 2.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF4404 PF14357.6 CBY07938.1 - 2 9.1 11.2 0.35 11.6 1.8 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 CBY07938.1 - 7 6.7 7.3 5.6 7.0 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spt4 PF06093.13 CBY07939.1 - 3.2e-32 110.5 0.3 4e-32 110.1 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Spc7 PF08317.11 CBY07940.1 - 0.00089 18.2 18.1 0.00089 18.2 18.1 2.5 2 1 1 3 3 3 2 Spc7 kinetochore protein HemX PF04375.14 CBY07940.1 - 0.0023 17.3 6.7 0.027 13.8 0.2 2.4 1 1 1 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase CENP-K PF11802.8 CBY07940.1 - 0.0076 15.9 16.1 0.012 15.2 16.1 1.4 1 0 0 1 1 1 1 Centromere-associated protein K Lectin_N PF03954.14 CBY07940.1 - 0.022 14.5 4.6 1.6 8.5 0.1 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Seryl_tRNA_N PF02403.22 CBY07940.1 - 0.024 14.8 6.8 0.024 14.8 6.8 3.6 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF641 PF04859.12 CBY07940.1 - 0.032 14.6 15.9 0.043 14.2 3.2 3.0 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 CBY07940.1 - 0.037 14.7 10.2 0.26 11.9 2.4 2.7 2 0 0 2 2 2 0 SlyX FUSC PF04632.12 CBY07940.1 - 0.068 11.7 0.9 0.079 11.5 0.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 CBY07940.1 - 0.072 13.1 10.7 0.8 9.8 2.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HCMV_UL139 PF12507.8 CBY07940.1 - 0.082 13.3 6.2 1.2 9.6 0.1 2.9 1 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein Syntaxin_2 PF14523.6 CBY07940.1 - 0.089 13.2 0.2 0.089 13.2 0.2 2.8 1 1 1 2 2 2 0 Syntaxin-like protein TRAF_BIRC3_bd PF16673.5 CBY07940.1 - 0.11 12.4 0.2 0.11 12.4 0.2 3.4 3 1 1 4 4 3 0 TNF receptor-associated factor BIRC3 binding domain DUF2570 PF10828.8 CBY07940.1 - 0.15 11.9 0.2 0.15 11.9 0.2 3.2 2 1 2 4 4 3 0 Protein of unknown function (DUF2570) FlaC_arch PF05377.11 CBY07940.1 - 0.16 12.4 10.1 11 6.5 0.1 4.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) WXG100 PF06013.12 CBY07940.1 - 0.19 12.0 2.9 0.43 10.8 0.9 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG AAA_13 PF13166.6 CBY07940.1 - 0.21 10.2 24.1 0.81 8.3 16.0 2.8 1 1 1 2 2 2 0 AAA domain DUF2730 PF10805.8 CBY07940.1 - 0.21 11.7 8.3 0.95 9.6 0.8 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.19 CBY07940.1 - 0.27 9.1 8.3 0.41 8.5 8.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 CBY07940.1 - 0.34 11.3 24.1 16 5.9 24.1 2.3 1 1 0 1 1 1 0 Fez1 HOOK PF05622.12 CBY07940.1 - 0.45 8.6 26.7 0.016 13.4 16.4 2.2 1 1 1 2 2 2 0 HOOK protein THOC7 PF05615.13 CBY07940.1 - 0.49 10.7 20.3 26 5.1 19.8 2.8 1 1 0 1 1 1 0 Tho complex subunit 7 DUF2968 PF11180.8 CBY07940.1 - 0.65 9.6 12.7 0.85 9.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Syntaxin-6_N PF09177.11 CBY07940.1 - 1.2 9.8 13.7 16 6.1 0.5 3.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cep57_CLD_2 PF14197.6 CBY07940.1 - 1.4 9.0 19.8 0.28 11.3 7.9 3.4 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 KxDL PF10241.9 CBY07940.1 - 2.1 8.7 13.6 1 9.7 0.6 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF4407 PF14362.6 CBY07940.1 - 2.3 7.5 20.2 15 4.8 18.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 CBY07940.1 - 2.6 8.4 25.8 2.1 8.7 10.0 2.6 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 CBY07940.1 - 3.6 6.7 15.0 1.3 8.2 4.3 2.2 1 1 1 2 2 2 0 TMPIT-like protein Macoilin PF09726.9 CBY07940.1 - 5.7 5.4 20.5 4.3 5.8 19.2 1.4 1 1 0 1 1 1 0 Macoilin family Fib_alpha PF08702.10 CBY07940.1 - 6.6 6.9 12.9 14 5.9 1.7 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.9 CBY07940.1 - 6.7 6.9 20.1 3.7 7.8 17.6 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein MINDY_DUB PF04424.13 CBY07941.1 - 1.5e-24 86.3 0.2 2.9e-24 85.4 0.2 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase DUF3242 PF11586.8 CBY07941.1 - 0.064 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Lys PF00062.20 CBY07941.1 - 0.074 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family SH2 PF00017.24 CBY07942.1 - 2e-12 47.0 0.1 3.7e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 SH2 domain Inovirus_Gp2 PF11726.8 CBY07942.1 - 0.094 12.7 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Inovirus Gp2 DENN PF02141.21 CBY07943.1 - 3.8e-29 102.0 6.9 9e-29 100.7 6.9 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 CBY07943.1 - 2e-13 50.9 0.2 4.9e-13 49.6 0.2 1.7 1 0 0 1 1 1 1 uDENN domain OmpH PF03938.14 CBY07943.1 - 0.032 14.5 1.3 0.67 10.3 0.8 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UPAR_LY6_2 PF16975.5 CBY07943.1 - 0.075 13.2 1.7 0.2 11.9 1.7 1.7 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 ITAM_Cys-rich PF10538.9 CBY07943.1 - 0.16 11.7 1.1 0.41 10.4 1.1 1.6 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif PLAC8 PF04749.17 CBY07944.1 - 2.5e-14 54.1 19.4 3.2e-14 53.7 19.4 1.1 1 0 0 1 1 1 1 PLAC8 family DUF2439 PF10382.9 CBY07945.1 - 2.3e-08 34.2 0.7 6.7e-08 32.8 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Mito_carr PF00153.27 CBY07946.1 - 9.3e-39 131.3 6.6 4.9e-17 61.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1304 PF06993.12 CBY07946.1 - 0.0012 18.8 5.9 0.035 14.1 0.5 3.0 4 0 0 4 4 4 2 Protein of unknown function (DUF1304) MFS_1 PF07690.16 CBY07947.1 - 0.018 14.0 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily TraS PF10624.9 CBY07947.1 - 0.05 13.5 0.3 0.058 13.3 0.3 1.1 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS OAD_gamma PF04277.13 CBY07947.1 - 0.055 14.1 0.0 0.08 13.6 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Rad9 PF04139.13 CBY07949.1 - 2e-21 76.6 0.4 2.6e-21 76.2 0.4 1.1 1 0 0 1 1 1 1 Rad9 S1 PF00575.23 CBY07950.1 - 2.1e-19 69.6 0.2 3.1e-19 69.1 0.2 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 CBY07950.1 - 7.3e-14 51.9 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 CBY07950.1 - 1.7e-06 28.3 0.0 3.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 eRF1_1 PF03463.15 CBY07952.1 - 5.7e-44 149.2 1.5 1e-43 148.4 1.5 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 CBY07952.1 - 1.5e-25 90.0 0.1 2.5e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CBY07952.1 - 1.2e-21 77.3 0.0 3.1e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 zf-B_box PF00643.24 CBY07953.1 - 0.62 10.3 11.5 0.16 12.1 7.6 1.9 2 0 0 2 2 2 0 B-box zinc finger Cupin_4 PF08007.12 CBY07955.1 - 1.2e-58 199.1 0.1 1.4e-58 198.9 0.1 1.0 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 CBY07955.1 - 8.8e-09 35.4 0.4 2.4e-07 30.7 0.2 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CBY07955.1 - 0.0044 17.4 0.6 0.01 16.3 0.1 1.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase Mito_carr PF00153.27 CBY07956.1 - 7.8e-54 179.6 1.0 1.2e-18 66.8 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF448 PF04296.13 CBY07956.1 - 0.039 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF448) B PF02216.16 CBY07957.1 - 0.025 14.5 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 B domain FACT-Spt16_Nlob PF14826.6 CBY07957.1 - 0.033 14.0 0.6 0.036 13.9 0.6 1.2 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain HTH_37 PF13744.6 CBY07957.1 - 0.054 13.4 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain UBA_4 PF14555.6 CBY07957.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 UBA-like domain zf-MYND PF01753.18 CBY07958.1 - 4.6e-10 39.4 19.5 4.6e-10 39.4 19.5 2.8 2 1 0 2 2 2 1 MYND finger AIG2_2 PF13772.6 CBY07958.1 - 0.11 12.8 0.0 0.22 12.0 0.0 1.4 1 1 0 1 1 1 0 AIG2-like family zf-C6H2 PF15801.5 CBY07958.1 - 0.75 10.1 19.9 0.086 13.2 13.5 2.5 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PI3_PI4_kinase PF00454.27 CBY07960.1 - 1.7e-55 188.5 0.7 1.7e-55 188.5 0.7 2.8 2 1 1 3 3 3 1 Phosphatidylinositol 3- and 4-kinase Neur_chan_LBD PF02931.23 CBY07960.1 - 1.8e-40 138.7 0.3 4.8e-40 137.3 0.3 1.8 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY07960.1 - 3.7e-32 112.3 4.2 1.5e-29 103.8 2.3 3.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region FAT PF02259.23 CBY07960.1 - 1.2e-27 97.1 17.8 4.4e-21 75.5 1.4 4.8 4 1 0 4 4 4 2 FAT domain DUF3385 PF11865.8 CBY07960.1 - 1.9e-17 63.6 0.6 1.9e-16 60.4 0.1 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) FATC PF02260.20 CBY07960.1 - 4.2e-13 48.9 0.1 9.7e-13 47.7 0.1 1.7 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 CBY07960.1 - 1.4e-12 47.8 4.9 5.9e-12 45.9 2.3 3.6 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain VHS PF00790.19 CBY07960.1 - 0.00011 22.0 2.9 0.1 12.5 0.0 3.9 3 1 0 3 3 3 2 VHS domain HEAT PF02985.22 CBY07960.1 - 0.056 13.7 2.8 8.3 7.0 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat DUF4042 PF13251.6 CBY07960.1 - 0.23 11.1 2.6 0.97 9.1 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) WD40 PF00400.32 CBY07961.1 - 3e-32 110.1 25.5 1.6e-06 28.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY07961.1 - 1.8e-18 66.6 4.9 0.0082 16.4 0.0 6.9 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY07961.1 - 2.3e-05 23.5 0.3 3.3 6.6 0.0 4.2 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CBY07961.1 - 0.00028 20.7 0.0 0.19 11.7 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 CBY07961.1 - 0.0022 16.1 1.3 0.016 13.3 0.2 2.5 1 1 2 3 3 3 1 IKI3 family Gmad1 PF10647.9 CBY07961.1 - 0.073 12.8 0.2 12 5.6 0.0 2.7 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Utp8 PF10395.9 CBY07961.1 - 0.099 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Utp8 family Thioredoxin PF00085.20 CBY07962.1 - 1.5e-107 352.6 4.1 3.4e-28 97.7 0.0 4.1 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_2 PF13098.6 CBY07962.1 - 9.9e-27 93.6 1.0 2e-05 25.0 0.0 4.5 4 0 0 4 4 4 4 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY07962.1 - 9.6e-17 61.1 0.3 0.027 14.8 0.0 4.8 4 0 0 4 4 4 4 Thioredoxin-like Thioredoxin_7 PF13899.6 CBY07962.1 - 1.3e-14 54.1 5.6 0.015 15.4 0.0 4.4 4 0 0 4 4 4 4 Thioredoxin-like AhpC-TSA PF00578.21 CBY07962.1 - 9.1e-14 51.4 4.1 0.0025 17.7 0.0 4.3 3 1 1 4 4 4 4 AhpC/TSA family OST3_OST6 PF04756.13 CBY07962.1 - 4.5e-12 45.9 0.5 0.0067 15.8 0.1 4.1 4 0 0 4 4 4 4 OST3 / OST6 family, transporter family TraF PF13728.6 CBY07962.1 - 2.2e-09 37.5 0.0 0.14 11.9 0.0 4.3 4 0 0 4 4 4 3 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CBY07962.1 - 6.9e-07 29.2 1.6 1.6 8.8 0.0 4.5 4 0 0 4 4 4 2 Thioredoxin domain Redoxin PF08534.10 CBY07962.1 - 1.8e-06 27.8 9.2 0.2 11.4 0.0 4.2 3 1 1 4 4 4 2 Redoxin Glutaredoxin PF00462.24 CBY07962.1 - 0.0028 17.8 8.6 6.6 7.0 0.0 4.7 4 0 0 4 4 4 2 Glutaredoxin HyaE PF07449.11 CBY07962.1 - 0.0034 17.3 0.0 0.7 9.9 0.0 3.6 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 CBY07962.1 - 0.022 14.9 4.7 8.4 6.5 0.1 4.8 4 2 2 6 6 6 0 Thioredoxin Thioredoxin_5 PF13743.6 CBY07962.1 - 0.095 12.4 1.8 11 5.7 0.0 4.3 4 2 2 6 6 6 0 Thioredoxin UPRTase PF14681.6 CBY07963.1 - 8e-70 234.5 0.0 1.2e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 CBY07963.1 - 3.3e-51 173.8 0.1 5.2e-51 173.2 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 CBY07963.1 - 0.00015 21.6 0.0 0.00035 20.5 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 CBY07963.1 - 0.0034 17.9 0.0 0.0067 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CBY07963.1 - 0.024 14.4 0.1 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 CBY07963.1 - 0.03 14.5 0.0 0.089 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 CBY07963.1 - 0.37 10.4 2.6 2.2 7.9 2.6 2.1 1 1 0 1 1 1 0 Dephospho-CoA kinase AAA_17 PF13207.6 CBY07963.1 - 0.48 10.8 2.3 13 6.2 1.4 3.0 2 1 0 2 2 2 0 AAA domain PGM_PMM_I PF02878.16 CBY07964.1 - 3.5e-35 120.7 0.0 9.4e-35 119.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CBY07964.1 - 1.5e-19 70.5 0.0 6.4e-19 68.5 0.0 2.1 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CBY07964.1 - 1.3e-12 47.9 0.1 2.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CBY07964.1 - 2.4e-06 27.6 0.0 7.3e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MOZ_SAS PF01853.18 CBY07965.1 - 1.4e-74 249.6 0.4 2.2e-74 249.0 0.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY07965.1 - 5.5e-22 77.1 0.8 5.5e-22 77.1 0.8 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 CBY07965.1 - 7e-17 61.1 0.1 2.4e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain BUD22 PF09073.10 CBY07965.1 - 0.043 13.2 10.0 0.076 12.3 10.0 1.3 1 0 0 1 1 1 0 BUD22 Acetyltransf_7 PF13508.7 CBY07965.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Chromo PF00385.24 CBY07965.1 - 0.12 12.3 1.6 0.26 11.2 0.1 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_1 PF00583.25 CBY07965.1 - 0.18 12.0 0.0 0.5 10.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ribosomal_L31e PF01198.19 CBY07965.1 - 1.1 9.5 4.9 1.1 9.6 2.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L31e Syja_N PF02383.18 CBY07966.1 - 4.4e-66 223.4 0.1 5.6e-66 223.0 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain PLAC8 PF04749.17 CBY07969.1 - 0.00053 20.9 4.9 0.00092 20.2 4.9 1.4 1 0 0 1 1 1 1 PLAC8 family CYSTM PF12734.7 CBY07969.1 - 2.8 8.3 7.8 9 6.7 0.5 2.4 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Forkhead PF00250.18 CBY07971.1 - 1.2e-19 70.3 0.1 2.7e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain VWD PF00094.25 CBY07972.1 - 5.2e-54 182.8 2.9 6.2e-28 98.1 0.0 4.5 3 1 1 4 4 4 4 von Willebrand factor type D domain Ldl_recept_a PF00057.18 CBY07972.1 - 1.7e-31 108.1 141.4 1e-09 38.5 11.1 21.2 20 0 0 20 20 20 9 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 CBY07972.1 - 1.3e-27 95.8 287.6 1.8e-09 37.6 8.0 22.8 19 2 2 21 21 21 11 Thrombospondin type 1 domain TIL PF01826.17 CBY07972.1 - 7.3e-23 80.6 108.4 6.3e-10 39.1 17.8 31.5 26 6 3 29 29 29 9 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.13 CBY07972.1 - 4.8e-07 29.4 20.3 1.7e-05 24.4 6.3 19.2 20 0 0 20 20 20 5 Pacifastin inhibitor (LCMII) VWC PF00093.18 CBY07972.1 - 0.0012 19.1 8.1 0.0012 19.1 8.1 30.6 20 9 6 27 27 27 6 von Willebrand factor type C domain EphA2_TM PF14575.6 CBY07973.1 - 0.011 16.6 0.2 0.037 14.9 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM100 PF16311.5 CBY07973.1 - 0.011 15.3 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 Cadherin_C_2 PF16492.5 CBY07973.1 - 0.012 16.3 0.2 0.4 11.4 0.0 2.7 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal PRIMA1 PF16101.5 CBY07973.1 - 0.014 15.4 2.5 0.094 12.8 0.0 2.7 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 T2SSM PF04612.12 CBY07973.1 - 0.087 12.9 0.1 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M TMEM154 PF15102.6 CBY07973.1 - 0.21 11.5 0.2 0.47 10.3 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family FGFR3_TM PF18123.1 CBY07973.1 - 1.4 8.5 13.2 0.19 11.3 8.0 2.0 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain MFS_1 PF07690.16 CBY07974.1 - 2.6e-10 39.8 21.4 3.3e-10 39.4 21.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY07974.1 - 2e-09 36.9 1.4 3e-09 36.3 1.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Zip PF02535.22 CBY07974.1 - 0.024 13.9 0.4 0.057 12.6 0.3 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter PI3_PI4_kinase PF00454.27 CBY07975.1 - 1.3e-29 103.8 0.0 3.8e-21 76.0 0.1 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CBY07975.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PI3Ka PF00613.20 CBY07975.1 - 0.11 11.9 0.1 0.3 10.4 0.1 1.8 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) LSM14 PF12701.7 CBY07976.1 - 1.1e-28 99.1 0.0 2e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CBY07976.1 - 6.4e-08 33.4 11.4 6.4e-08 33.4 11.4 3.8 2 2 1 3 3 3 1 FDF domain SM-ATX PF14438.6 CBY07976.1 - 2.4e-06 27.6 0.0 4.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Golgin_A5 PF09787.9 CBY07977.1 - 0.0018 17.8 11.1 0.0021 17.6 11.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF4515 PF14988.6 CBY07977.1 - 0.0023 17.8 15.4 0.11 12.3 12.7 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4515) Tropomyosin_1 PF12718.7 CBY07977.1 - 0.0028 17.8 10.9 0.0037 17.4 10.9 1.2 1 0 0 1 1 1 1 Tropomyosin like Leu_zip PF15294.6 CBY07977.1 - 0.003 17.1 6.8 0.0036 16.8 6.8 1.1 1 0 0 1 1 1 1 Leucine zipper Csm1_N PF18504.1 CBY07977.1 - 0.003 17.9 13.5 0.0082 16.5 4.5 2.4 1 1 1 2 2 2 1 Csm1 N-terminal domain DUF1664 PF07889.12 CBY07977.1 - 0.0043 17.1 7.7 0.0067 16.5 7.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 CBY07977.1 - 0.0056 14.7 5.2 0.0063 14.5 5.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Atg14 PF10186.9 CBY07977.1 - 0.024 13.7 5.1 0.029 13.5 5.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Uds1 PF15456.6 CBY07977.1 - 0.037 14.2 10.0 0.098 12.8 10.0 1.7 1 1 0 1 1 1 0 Up-regulated During Septation BLOC1_2 PF10046.9 CBY07977.1 - 0.039 14.2 10.1 0.16 12.3 8.8 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tho2 PF11262.8 CBY07977.1 - 0.076 12.2 4.9 0.09 12.0 4.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4094 PF13334.6 CBY07977.1 - 0.08 13.4 7.2 3.3 8.2 4.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) TMF_TATA_bd PF12325.8 CBY07977.1 - 0.08 13.2 11.8 0.11 12.7 11.2 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 CBY07977.1 - 0.13 11.1 12.5 0.18 10.7 12.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CBY07977.1 - 0.17 11.4 6.1 0.19 11.3 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FemAB PF02388.16 CBY07977.1 - 0.23 10.3 7.0 0.3 9.9 7.0 1.1 1 0 0 1 1 1 0 FemAB family Mis14 PF08641.12 CBY07977.1 - 0.28 11.5 9.6 0.85 9.9 9.6 1.8 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Phlebovirus_NSM PF07246.11 CBY07977.1 - 0.3 10.4 7.2 0.35 10.2 7.2 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Dynein_attach_N PF15867.5 CBY07977.1 - 0.44 10.5 6.4 0.67 9.9 3.7 2.2 1 1 1 2 2 2 0 Dynein attachment factor N-terminus Fzo_mitofusin PF04799.13 CBY07977.1 - 0.46 10.0 7.8 0.67 9.5 7.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region TMPIT PF07851.13 CBY07977.1 - 0.49 9.6 6.0 0.56 9.4 6.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Macoilin PF09726.9 CBY07977.1 - 0.55 8.7 10.2 0.68 8.4 10.2 1.0 1 0 0 1 1 1 0 Macoilin family ADIP PF11559.8 CBY07977.1 - 0.72 9.9 15.8 1.3 9.0 15.4 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.9 CBY07977.1 - 0.96 9.4 14.1 0.9 9.5 7.5 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4407 PF14362.6 CBY07977.1 - 1.5 8.1 7.0 1.8 7.8 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 CBY07977.1 - 1.8 8.8 13.2 0.48 10.6 7.9 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 MotA_ExbB PF01618.16 CBY07977.1 - 2.1 8.1 3.6 16 5.3 0.2 2.1 1 1 1 2 2 2 0 MotA/TolQ/ExbB proton channel family YabA PF06156.13 CBY07977.1 - 3.6 8.3 12.0 3.2 8.4 5.8 2.1 1 1 1 2 2 2 0 Initiation control protein YabA OEP PF02321.18 CBY07977.1 - 6.2 6.6 14.8 50 3.6 14.8 2.2 1 1 0 1 1 1 0 Outer membrane efflux protein Chromo PF00385.24 CBY07979.1 - 1.5e-10 40.8 3.2 2.7e-06 27.2 0.7 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C12 PF01088.21 CBY07980.1 - 8.8e-53 179.2 0.0 1.4e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CBY07980.1 - 2.3e-06 27.4 2.0 4.6e-06 26.4 2.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Ets PF00178.22 CBY07981.1 - 1.2e-32 112.2 2.7 1.2e-32 112.2 2.7 1.9 2 0 0 2 2 2 1 Ets-domain NIDO PF06119.14 CBY07983.1 - 0.0053 17.7 0.0 0.019 15.9 0.0 2.0 1 0 0 1 1 1 1 Nidogen-like TMEM138 PF14935.6 CBY07984.1 - 1.9e-33 115.6 12.5 1.9e-33 115.6 12.5 1.3 2 0 0 2 2 2 1 Transmembrane protein 138 Yip1 PF04893.17 CBY07986.1 - 1.5e-09 37.9 10.9 1.9e-09 37.5 10.9 1.2 1 0 0 1 1 1 1 Yip1 domain Cytochrom_B558a PF05038.13 CBY07987.1 - 2.8e-39 134.6 0.1 3.4e-39 134.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit TPR_1 PF00515.28 CBY07988.1 - 4e-26 89.7 4.6 4.9e-08 32.5 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY07988.1 - 5.6e-18 63.5 2.3 5e-05 23.1 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 CBY07988.1 - 3e-14 53.3 0.3 1e-13 51.6 0.0 2.1 3 0 0 3 3 1 1 Potential Monad-binding region of RPAP3 TPR_11 PF13414.6 CBY07988.1 - 2.7e-12 46.2 1.1 6.7e-06 25.7 0.0 3.4 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.6 CBY07988.1 - 5.4e-12 44.9 4.3 0.0088 16.2 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY07988.1 - 4.3e-09 36.9 0.0 5.3e-06 27.0 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY07988.1 - 2.1e-07 30.5 0.1 0.0011 18.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY07988.1 - 2.4e-07 30.7 4.9 0.043 14.2 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY07988.1 - 3.2e-07 30.6 1.5 0.044 14.1 0.3 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY07988.1 - 1.6e-06 28.5 0.0 1.3 10.0 0.0 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY07988.1 - 4.8e-06 26.5 7.4 0.0091 16.1 0.1 4.5 3 1 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 CBY07988.1 - 7.6e-06 26.3 0.3 0.022 15.3 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY07988.1 - 5.8e-05 23.2 0.0 0.045 13.9 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY07988.1 - 8.6e-05 22.9 0.4 0.34 11.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY07988.1 - 0.0017 18.2 0.1 2.6 8.0 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF357 PF04010.13 CBY07988.1 - 0.0077 16.3 0.1 0.035 14.2 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF357) Coatomer_E PF04733.14 CBY07988.1 - 0.0089 15.5 0.2 0.026 13.9 0.2 1.8 1 1 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 CBY07988.1 - 0.014 15.6 0.9 0.045 14.0 0.3 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Vps39_2 PF10367.9 CBY07988.1 - 0.49 10.9 2.6 0.59 10.6 0.1 2.3 3 0 0 3 3 2 0 Vacuolar sorting protein 39 domain 2 AAA_2 PF07724.14 CBY07989.1 - 1e-40 139.6 0.0 1.7e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 CBY07989.1 - 1e-13 51.7 0.0 7.1e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY07989.1 - 2.5e-13 49.8 0.0 4e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CBY07989.1 - 4e-13 48.3 0.1 2.9e-06 27.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat AAA_5 PF07728.14 CBY07989.1 - 1.9e-11 44.1 0.0 4.5e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank_4 PF13637.6 CBY07989.1 - 4.3e-10 39.9 0.0 0.00021 21.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AAA PF00004.29 CBY07989.1 - 6.3e-10 39.6 0.0 1.3e-07 32.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBY07989.1 - 1.6e-07 31.2 0.0 5.2e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 CBY07989.1 - 2.6e-06 27.3 0.0 4.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBY07989.1 - 1.5e-05 24.4 0.1 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin Ank_5 PF13857.6 CBY07989.1 - 1.6e-05 25.1 0.0 0.039 14.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 CBY07989.1 - 8e-05 23.1 0.0 0.0037 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Torsin PF06309.11 CBY07989.1 - 0.00062 19.9 0.1 0.0021 18.2 0.0 1.9 2 0 0 2 2 1 1 Torsin AAA_22 PF13401.6 CBY07989.1 - 0.00073 19.8 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CBY07989.1 - 0.0063 15.7 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain RuvB_N PF05496.12 CBY07989.1 - 0.0067 16.2 0.0 0.017 14.9 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CBY07989.1 - 0.0083 16.0 0.0 0.045 13.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBY07989.1 - 0.02 14.9 0.0 0.06 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBY07989.1 - 0.061 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBY07989.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain YchF-GTPase_C PF06071.13 CBY07989.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF933) RNA_helicase PF00910.22 CBY07989.1 - 0.11 12.8 2.6 0.3 11.5 0.3 3.0 3 1 0 3 3 3 0 RNA helicase F5_F8_type_C PF00754.25 CBY07990.1 - 0.00021 21.4 0.0 0.00036 20.6 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 CBY07990.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Rad10 PF03834.14 CBY07991.1 - 0.14 12.2 0.0 0.14 12.2 0.0 2.0 3 0 0 3 3 3 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) IBR PF01485.21 CBY07991.1 - 0.24 11.6 10.3 0.64 10.3 10.3 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Siva PF05458.12 CBY07991.1 - 0.31 10.7 7.2 0.17 11.5 5.2 1.6 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-B_box PF00643.24 CBY07991.1 - 0.73 10.0 10.4 1.3 9.2 10.4 1.4 1 0 0 1 1 1 0 B-box zinc finger C1_1 PF00130.22 CBY07991.1 - 1.7 8.6 11.7 4.1 7.4 11.7 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UBZ_FAAP20 PF15750.5 CBY07992.1 - 0.0013 18.6 1.3 0.17 11.8 0.2 2.6 2 0 0 2 2 2 1 Ubiquitin-binding zinc-finger DUF4451 PF14616.6 CBY07992.1 - 0.017 15.3 4.3 0.044 14.0 3.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) Zn-C2H2_12 PF18112.1 CBY07992.1 - 0.043 14.3 12.4 0.39 11.2 0.2 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 CBY07992.1 - 0.07 13.0 4.9 5 7.0 0.2 3.7 3 0 0 3 3 3 0 Rad50 zinc hook motif FYVE PF01363.21 CBY07992.1 - 0.088 13.0 9.4 0.095 12.9 0.0 3.3 3 0 0 3 3 3 0 FYVE zinc finger TRAF6_Z2 PF18048.1 CBY07992.1 - 0.45 10.6 0.0 0.45 10.6 0.0 3.1 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 Prok-RING_4 PF14447.6 CBY07992.1 - 1 9.3 9.3 3.6 7.5 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 CBY07992.1 - 1.1 9.7 9.7 3.6 7.9 0.2 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.11 CBY07992.1 - 1.9 8.5 8.6 0.87 9.5 0.4 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 CBY07992.1 - 1.9 8.1 5.1 36 4.1 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-RING_2 PF13639.6 CBY07992.1 - 4.3 7.8 8.9 36 4.8 0.1 3.6 3 0 0 3 3 3 0 Ring finger domain zf-C2H2 PF00096.26 CBY07992.1 - 4.4 8.0 7.5 4.6 7.9 0.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 CBY07992.1 - 5.4 7.4 6.0 42 4.5 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon DHHC PF01529.20 CBY07993.1 - 1.2e-27 96.7 14.5 1.2e-27 96.7 14.5 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase UPF0489 PF12640.7 CBY07995.1 - 5.1e-20 72.4 0.2 1.4e-19 71.0 0.2 1.7 1 1 0 1 1 1 1 UPF0489 domain EF-hand_1 PF00036.32 CBY07997.1 - 6.2e-08 31.7 13.1 0.018 14.6 0.1 6.1 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 CBY07997.1 - 1.6e-07 31.6 20.7 0.0005 20.5 1.1 4.8 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CBY07997.1 - 2.9e-06 26.8 13.7 0.025 14.5 0.1 6.1 6 0 0 6 6 6 2 EF-hand domain Homeodomain PF00046.29 CBY07997.1 - 0.044 13.6 0.1 11 6.0 0.0 2.8 2 0 0 2 2 2 0 Homeodomain EF-hand_8 PF13833.6 CBY07997.1 - 0.19 11.6 15.1 0.81 9.6 0.6 5.2 4 2 2 6 6 6 0 EF-hand domain pair EF-hand_5 PF13202.6 CBY07997.1 - 0.19 11.3 8.3 3.9 7.1 0.0 4.4 5 0 0 5 5 5 0 EF hand DNA_photolyase PF00875.18 CBY07998.1 - 3.2e-27 95.5 0.1 5.2e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 CBY07998.1 - 7e-26 90.9 2.4 1.3e-25 90.1 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase zf-H2C2_5 PF13909.6 CBY07999.1 - 4.1e-19 68.0 17.3 2.8e-07 30.2 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CBY07999.1 - 2.8e-15 55.9 23.0 2.2e-07 31.0 1.4 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY07999.1 - 1.8e-10 40.7 19.2 0.00078 19.8 0.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY07999.1 - 2.6e-08 34.0 16.9 0.022 15.6 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 CBY07999.1 - 0.3 11.4 10.3 1.8 8.9 0.0 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding OrsD PF12013.8 CBY07999.1 - 4.1 7.9 11.1 12 6.4 0.2 3.4 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Zn_ribbon_SprT PF17283.2 CBY07999.1 - 4.9 7.2 12.9 18 5.3 6.7 2.8 2 1 0 2 2 2 0 SprT-like zinc ribbon domain C1_2 PF03107.16 CBY07999.1 - 5.2 7.5 8.5 34 4.8 0.1 3.4 3 0 0 3 3 3 0 C1 domain TSP_1 PF00090.19 CBY08000.1 - 4.5e-05 23.6 5.8 4.5e-05 23.6 5.8 5.2 4 0 0 4 4 4 2 Thrombospondin type 1 domain zf-AN1 PF01428.16 CBY08001.1 - 1.9e-18 66.3 33.7 3.5e-10 39.9 9.1 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CBY08001.1 - 0.0014 18.9 21.3 0.0088 16.4 6.8 2.5 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain LPP20 PF02169.16 CBY08001.1 - 0.036 14.4 2.8 0.062 13.7 2.8 1.4 1 0 0 1 1 1 0 LPP20 lipoprotein EloA-BP1 PF15870.5 CBY08001.1 - 0.29 11.4 7.2 5.4 7.3 0.2 2.3 1 1 1 2 2 2 0 ElonginA binding-protein 1 CDP-OH_P_transf PF01066.21 CBY08002.1 - 8.9e-13 48.8 1.9 8.9e-13 48.8 1.9 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Septin PF00735.18 CBY08003.1 - 9.6e-98 326.9 0.4 9.6e-98 326.9 0.4 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CBY08003.1 - 4.2e-07 30.0 0.0 1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY08003.1 - 0.0011 19.0 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CBY08003.1 - 0.0011 19.4 0.1 0.0087 16.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 CBY08003.1 - 0.0034 17.6 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CBY08003.1 - 0.0036 17.6 0.2 0.016 15.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain Ras PF00071.22 CBY08003.1 - 0.0089 15.6 0.0 0.031 13.9 0.0 2.0 1 0 0 1 1 1 1 Ras family AAA_7 PF12775.7 CBY08003.1 - 0.032 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 CBY08003.1 - 0.041 13.1 7.5 1.5 7.9 0.0 3.5 3 1 1 4 4 4 0 G-protein alpha subunit DUF1890 PF09001.11 CBY08003.1 - 0.089 13.2 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) AAA_32 PF13654.6 CBY08003.1 - 0.099 11.4 15.2 0.17 10.6 0.0 2.6 2 2 0 2 2 2 0 AAA domain DUF87 PF01935.17 CBY08003.1 - 0.21 11.6 9.3 3.2 7.8 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Phage_Mu_Gam PF07352.12 CBY08003.1 - 0.25 11.2 10.6 0.11 12.4 6.8 2.4 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF382 PF04037.13 CBY08003.1 - 0.76 9.9 7.1 4.6 7.4 2.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF382) Dynamin_N PF00350.23 CBY08003.1 - 1.7 8.7 6.0 21 5.2 0.0 3.4 3 1 0 3 3 3 0 Dynamin family DUF3552 PF12072.8 CBY08003.1 - 6 6.2 20.4 10 5.5 20.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-Di19 PF05605.12 CBY08004.1 - 3.7e-15 56.0 1.5 3.7e-15 56.0 1.5 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.17 CBY08004.1 - 1.1e-12 47.5 7.4 1.1e-12 47.5 7.4 2.4 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-C2H2 PF00096.26 CBY08004.1 - 0.001 19.4 7.8 0.025 15.1 0.1 3.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type Di19_C PF14571.6 CBY08004.1 - 0.0012 19.3 0.7 0.0036 17.8 0.7 1.8 1 0 0 1 1 1 1 Stress-induced protein Di19, C-terminal zf-H2C2_2 PF13465.6 CBY08004.1 - 0.032 14.7 12.6 0.17 12.4 0.0 3.7 3 1 1 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY08004.1 - 0.97 10.4 0.1 0.97 10.4 0.1 4.8 3 2 0 3 3 3 0 C2H2-type zinc finger zf-FPG_IleRS PF06827.14 CBY08004.1 - 2.3 8.1 7.1 4.7 7.2 0.1 3.2 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DHR-2 PF06920.13 CBY08005.1 - 3.4e-67 227.3 5.6 3.4e-67 227.3 5.6 2.2 2 1 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 CBY08005.1 - 3.5e-45 154.2 1.2 1.1e-44 152.6 0.3 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 CBY08005.1 - 9.4e-07 28.1 0.0 1.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus HEAT_EZ PF13513.6 CBY08006.1 - 7.4e-31 106.2 1.9 4.8e-10 39.7 0.0 9.6 8 1 2 10 10 10 5 HEAT-like repeat HEAT PF02985.22 CBY08006.1 - 1e-19 68.9 14.5 0.062 13.6 0.1 12.0 12 0 0 12 12 11 4 HEAT repeat HEAT_2 PF13646.6 CBY08006.1 - 2.7e-14 53.3 0.1 0.0045 17.4 0.0 6.4 5 2 3 8 8 7 5 HEAT repeats Vac14_Fab1_bd PF12755.7 CBY08006.1 - 7.7e-13 48.9 0.9 0.49 11.0 0.0 7.1 5 3 3 9 9 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CBY08006.1 - 1.2e-12 48.2 1.7 0.0022 18.0 0.0 5.5 4 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBY08006.1 - 1.2e-09 37.3 0.5 0.0019 16.8 0.1 3.9 3 1 1 4 4 4 2 Adaptin N terminal region IBN_N PF03810.19 CBY08006.1 - 6.9e-09 35.5 0.2 7.6e-08 32.2 0.2 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 CBY08006.1 - 1.6e-08 34.4 0.2 0.03 13.9 0.0 5.6 4 2 2 6 6 6 2 CLASP N terminal Arm PF00514.23 CBY08006.1 - 3.8e-06 26.8 4.3 0.24 11.5 0.3 5.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 CBY08006.1 - 0.0013 18.0 3.2 5.1 6.1 0.0 5.7 4 2 2 6 6 6 1 RNAPII transcription regulator C-terminal Xpo1 PF08389.12 CBY08006.1 - 0.0029 17.7 3.3 3.6 7.6 0.1 4.8 3 1 1 5 5 5 1 Exportin 1-like protein DUF3689 PF12463.8 CBY08006.1 - 0.0095 15.3 0.1 0.32 10.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3689) TFCD_C PF12612.8 CBY08006.1 - 0.016 15.1 2.6 10 5.9 0.0 4.6 4 2 1 5 5 5 0 Tubulin folding cofactor D C terminal UNC45-central PF11701.8 CBY08006.1 - 0.054 13.5 1.0 3.5 7.6 0.1 3.8 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central TAFH PF07531.14 CBY08006.1 - 0.14 12.3 1.5 42 4.3 0.0 4.2 4 1 1 5 5 5 0 NHR1 homology to TAF DCB PF16213.5 CBY08006.1 - 0.15 11.7 0.0 0.65 9.6 0.0 2.1 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 TIP120 PF08623.10 CBY08006.1 - 0.21 11.3 0.6 1.6e+02 2.0 0.0 4.4 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) DUF3456 PF11938.8 CBY08007.1 - 1e-45 156.0 5.5 1.2e-45 155.8 5.5 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Zw10 PF06248.13 CBY08007.1 - 0.07 11.7 0.8 0.099 11.2 0.8 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 APC_rep PF18797.1 CBY08007.1 - 0.17 12.8 2.6 0.61 11.1 0.1 2.5 2 0 0 2 2 2 0 Adenomatous polyposis coli (APC) repeat RNase_HII PF01351.18 CBY08009.1 - 8.7e-34 117.1 0.0 1e-33 116.8 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII Phosphodiest PF01663.22 CBY08011.1 - 1.2e-75 255.4 2.5 1.4e-75 255.1 2.5 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CBY08011.1 - 0.00025 20.5 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CBY08011.1 - 0.00084 18.8 0.0 0.0035 16.8 0.0 2.0 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.12 CBY08011.1 - 0.0016 18.6 0.0 0.0036 17.4 0.0 1.5 2 0 0 2 2 2 1 PglZ domain FixP_N PF14715.6 CBY08011.1 - 0.54 10.0 3.4 6.3 6.6 1.9 2.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Thioredoxin_16 PF18569.1 CBY08012.1 - 2.8e-07 30.5 0.0 5.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain GST_C PF00043.25 CBY08012.1 - 9.7e-06 25.7 0.0 2.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY08012.1 - 0.0016 18.6 0.1 0.0068 16.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY08012.1 - 0.002 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4054 PF13262.6 CBY08012.1 - 0.1 12.6 0.2 2.8 8.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4054) RAM PF15320.6 CBY08013.1 - 3.5e-05 24.3 0.9 3.5e-05 24.3 0.9 2.0 2 0 0 2 2 2 1 mRNA cap methylation, RNMT-activating mini protein SMN PF06003.12 CBY08013.1 - 0.057 12.7 5.0 0.069 12.4 5.0 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Myosin_head PF00063.21 CBY08014.1 - 1.2e-264 879.6 0.0 1.2e-264 879.6 0.0 2.3 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY08014.1 - 3.1e-145 485.6 247.5 4.2e-145 485.2 247.5 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY08014.1 - 0.0002 21.1 2.2 0.00054 19.7 2.2 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Sec2p PF06428.11 CBY08014.1 - 0.0066 16.4 4.5 0.0066 16.4 4.5 15.3 3 3 13 16 16 16 3 GDP/GTP exchange factor Sec2p IQ PF00612.27 CBY08014.1 - 0.059 13.2 1.3 2.7 8.0 0.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY08014.1 - 0.25 11.6 0.0 0.25 11.6 0.0 5.3 6 1 0 6 6 6 0 AAA domain AAA_16 PF13191.6 CBY08014.1 - 0.71 10.2 0.0 0.71 10.2 0.0 5.9 4 2 0 4 4 4 0 AAA ATPase domain Tau95 PF09734.9 CBY08015.1 - 1.2e-25 91.0 0.7 2.7e-25 89.8 0.7 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CBY08015.1 - 7.7e-11 42.3 0.0 4.3e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 Tau95 Triple barrel domain TFIIF_beta PF02270.15 CBY08015.1 - 6.7e-05 22.9 0.1 0.00015 21.8 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain CCDC92 PF14916.6 CBY08016.1 - 0.034 13.9 0.2 0.084 12.6 0.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function CLAMP PF14769.6 CBY08017.1 - 0.0029 18.0 3.1 0.0057 17.1 0.6 2.3 2 1 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 DSPc PF00782.20 CBY08018.1 - 2e-09 37.4 0.0 3.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBY08018.1 - 1.6e-06 27.9 0.2 2.8e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY08018.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Glycos_transf_2 PF00535.26 CBY08019.1 - 2.3e-30 105.6 0.0 5e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY08019.1 - 5.6e-11 42.8 2.5 8.8e-10 38.9 2.5 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 CBY08019.1 - 6.8e-08 32.7 0.0 1.2e-06 28.6 0.0 2.6 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CBY08019.1 - 0.00054 19.6 0.1 0.0015 18.1 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY08019.1 - 0.0012 18.4 0.0 0.007 15.9 0.0 2.1 1 1 1 2 2 2 1 Glycosyltransferase like family 2 FUN14 PF04930.15 CBY08020.1 - 9.6e-21 74.0 0.2 1.2e-20 73.7 0.2 1.1 1 0 0 1 1 1 1 FUN14 family BLOC1_2 PF10046.9 CBY08021.1 - 4.7e-17 62.1 1.5 1.3e-16 60.6 1.1 1.9 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peptidase_C48 PF02902.19 CBY08021.1 - 2.4e-12 47.2 0.2 1.1e-11 45.0 0.2 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Sec34 PF04136.15 CBY08021.1 - 0.051 13.5 0.9 0.12 12.3 0.9 1.6 1 0 0 1 1 1 0 Sec34-like family SCAPER_N PF16501.5 CBY08022.1 - 1.2e-33 115.0 1.1 1.2e-33 115.0 1.1 2.3 2 0 0 2 2 2 1 S phase cyclin A-associated protein in the endoplasmic reticulum Acetyltransf_1 PF00583.25 CBY08023.1 - 2.7e-14 53.4 0.0 3.3e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY08023.1 - 2e-10 40.9 0.1 3.8e-10 40.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY08023.1 - 2.2e-10 40.6 0.1 2.4e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY08023.1 - 1.6e-07 31.1 0.0 3.3e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CBY08023.1 - 0.00021 21.3 0.0 0.00029 20.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 CBY08023.1 - 0.0026 17.9 0.0 0.0053 16.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBY08023.1 - 0.0045 16.5 0.0 0.0049 16.4 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CBY08023.1 - 0.0059 17.3 0.0 0.0067 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY08023.1 - 0.016 15.3 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY08023.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Nudix_hydro PF18290.1 CBY08023.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Nudix hydrolase domain Hormone_recep PF00104.30 CBY08024.1 - 5e-33 114.4 0.2 1.2e-32 113.1 0.2 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CBY08024.1 - 2.4e-31 108.0 18.0 3.7e-31 107.4 18.0 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Pox_VLTF3 PF04947.14 CBY08024.1 - 0.17 11.6 1.4 1.2 8.9 0.1 2.5 3 0 0 3 3 3 0 Poxvirus Late Transcription Factor VLTF3 like Hexapep PF00132.24 CBY08025.1 - 0.00034 20.2 12.5 0.0044 16.7 0.5 4.4 3 2 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Beta_elim_lyase PF01212.21 CBY08026.1 - 6.4e-40 137.3 0.0 7.8e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase HAMP_N3 PF18575.1 CBY08026.1 - 0.036 13.6 0.0 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 HAMP N-terminal domain 3 GRIP PF01465.20 CBY08027.1 - 1.5e-15 56.8 0.0 5.2e-15 55.1 0.0 2.1 1 0 0 1 1 1 1 GRIP domain Rab_bind PF16704.5 CBY08027.1 - 3.1e-11 43.1 4.5 3.1e-11 43.1 4.5 6.8 8 0 0 8 8 8 1 Rab binding domain Rootletin PF15035.6 CBY08027.1 - 0.0061 16.6 16.0 0.0061 16.6 16.0 10.1 2 2 5 8 8 8 1 Ciliary rootlet component, centrosome cohesion TolA_bind_tri PF16331.5 CBY08027.1 - 0.0065 16.5 3.0 0.0065 16.5 3.0 13.8 8 3 5 13 13 13 1 TolA binding protein trimerisation Exotox-A_target PF09102.10 CBY08027.1 - 0.093 12.7 2.9 0.097 12.7 0.4 2.4 2 0 0 2 2 2 0 Exotoxin A, targeting DUF3786 PF12654.7 CBY08027.1 - 0.47 10.0 4.6 0.29 10.7 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) Nse4_C PF08743.10 CBY08027.1 - 0.69 10.2 7.1 5 7.5 1.0 3.9 2 0 0 2 2 2 0 Nse4 C-terminal BRI3BP PF14965.6 CBY08027.1 - 7.1 6.1 6.4 13 5.3 0.1 3.9 3 0 0 3 3 3 0 Negative regulator of p53/TP53 Lipase_GDSL_lke PF16255.5 CBY08028.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase FTA4 PF13093.6 CBY08028.1 - 0.15 11.9 2.9 0.25 11.2 3.0 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PALP PF00291.25 CBY08031.1 - 1.2e-58 198.9 0.0 1.5e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_transf_28 PF03033.20 CBY08031.1 - 0.051 13.6 0.0 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain An_peroxidase PF03098.15 CBY08032.1 - 1.9e-166 554.7 0.0 2.6e-166 554.3 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Mucin2_WxxW PF13330.6 CBY08032.1 - 3.5e-41 139.9 3.7 1.2e-20 74.1 0.7 3.8 3 0 0 3 3 3 2 Mucin-2 protein WxxW repeating region NIP_1 PF08995.10 CBY08033.1 - 2.2 8.7 9.4 0.84 10.1 6.6 1.7 2 0 0 2 2 2 0 Necrosis inducing protein-1 RR_TM4-6 PF06459.12 CBY08034.1 - 0.0028 17.5 10.3 0.0029 17.5 10.3 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 LYRIC PF15686.5 CBY08034.1 - 0.036 13.6 23.1 0.048 13.2 23.1 1.4 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family SRP-alpha_N PF04086.13 CBY08034.1 - 0.096 12.6 22.9 0.11 12.4 22.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Neur_chan_memb PF02932.16 CBY08034.1 - 0.11 12.5 6.2 0.12 12.4 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dsh_C PF12316.8 CBY08034.1 - 0.41 11.0 9.8 0.65 10.4 9.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SAPS PF04499.15 CBY08034.1 - 0.52 9.0 5.7 0.51 9.1 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 CBY08034.1 - 0.57 9.1 10.1 0.64 9.0 10.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 CBY08034.1 - 0.71 10.2 24.3 0.99 9.7 24.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.6 CBY08034.1 - 4 6.7 6.8 4.6 6.5 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 CBY08034.1 - 5 5.1 8.3 5.5 5.0 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CBY08034.1 - 5.5 5.2 17.7 6.8 4.9 17.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CBY08034.1 - 5.7 5.6 14.2 7.3 5.2 14.2 1.1 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 CBY08035.1 - 1.3e-09 37.8 0.2 4.9e-09 35.9 0.2 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY08035.1 - 0.0031 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif EF1_GNE PF00736.19 CBY08036.1 - 6e-34 116.1 1.2 6e-34 116.1 1.2 2.0 2 1 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CBY08036.1 - 7.2e-08 32.7 5.2 7.2e-08 32.7 5.2 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region CCDC106 PF15794.5 CBY08036.1 - 0.01 15.5 1.2 0.017 14.9 1.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Prefoldin_2 PF01920.20 CBY08036.1 - 0.044 13.7 0.3 0.044 13.7 0.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.21 CBY08036.1 - 0.077 13.1 0.1 0.077 13.1 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor Striatin PF08232.12 CBY08036.1 - 0.1 13.2 6.5 0.041 14.5 3.8 1.7 2 0 0 2 2 2 0 Striatin family FtsH_ext PF06480.15 CBY08037.1 - 0.15 12.4 0.8 0.38 11.1 0.0 2.0 3 0 0 3 3 3 0 FtsH Extracellular ABC_membrane PF00664.23 CBY08038.1 - 4.4e-71 239.7 31.8 4.6e-38 131.4 13.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY08038.1 - 1.6e-52 177.7 0.1 8.9e-30 104.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBY08038.1 - 1.1e-07 31.5 10.9 0.0074 15.8 0.0 4.4 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY08038.1 - 2e-05 24.6 0.7 0.0072 16.2 0.2 2.6 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CBY08038.1 - 2.6e-05 24.3 3.6 0.12 12.4 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_7 PF12775.7 CBY08038.1 - 0.00013 21.5 0.3 0.008 15.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 CBY08038.1 - 0.00019 21.7 0.3 0.048 13.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CBY08038.1 - 0.00046 19.9 1.7 0.27 11.0 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CBY08038.1 - 0.0017 18.8 0.5 0.11 12.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 CBY08038.1 - 0.011 15.8 2.5 2.2 8.3 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 CBY08038.1 - 0.012 15.5 4.4 11 5.8 0.1 4.3 2 2 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 CBY08038.1 - 0.014 15.7 0.2 0.46 10.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 CBY08038.1 - 0.016 15.3 4.3 0.053 13.6 0.0 3.1 3 0 0 3 3 3 0 Dynamin family T2SSE PF00437.20 CBY08038.1 - 0.021 13.9 1.6 0.024 13.7 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 CBY08038.1 - 0.026 13.8 0.2 0.4 9.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 CBY08038.1 - 0.036 13.8 0.8 4.4 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CBY08038.1 - 0.12 12.9 0.3 13 6.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 CBY08038.1 - 0.12 12.0 1.2 18 5.0 0.3 3.1 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 CBY08038.1 - 0.18 10.7 0.7 6.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CBY08038.1 - 0.61 9.6 4.5 0.75 9.4 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CBY08038.1 - 2.9 8.4 12.3 14 6.1 5.7 3.0 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CBY08038.1 - 2.9 7.6 5.6 7.5 6.2 3.4 2.5 2 1 0 2 2 2 0 AAA domain PDZ PF00595.24 CBY08039.1 - 1.4e-06 28.5 0.1 2e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Neur_chan_memb PF02932.16 CBY08040.1 - 3.1e-69 233.7 21.2 1.6e-54 185.5 15.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY08040.1 - 1.6e-67 227.1 5.6 2.1e-67 226.8 5.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain NapB PF03892.14 CBY08041.1 - 0.031 14.3 0.1 0.087 12.8 0.1 1.7 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Mucin PF01456.17 CBY08041.1 - 0.98 9.4 15.1 1.9 8.5 15.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein LCCL PF03815.19 CBY08042.1 - 7.2e-05 22.8 0.6 0.00018 21.6 0.6 1.6 1 0 0 1 1 1 1 LCCL domain Protocadherin PF08374.11 CBY08042.1 - 0.045 13.7 0.4 0.045 13.7 0.4 1.8 2 0 0 2 2 2 0 Protocadherin DUF4006 PF13179.6 CBY08042.1 - 0.16 11.9 0.6 1.4 8.9 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Zona_pellucida PF00100.23 CBY08043.1 - 1.1e-43 149.9 2.9 1.3e-43 149.7 2.9 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain dsRBD2 PF17842.1 CBY08043.1 - 0.11 12.6 0.2 0.29 11.3 0.2 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 Dimer_Tnp_hAT PF05699.14 CBY08044.1 - 0.00075 19.2 0.2 0.0013 18.5 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SCP2 PF02036.17 CBY08045.1 - 2.2e-26 92.3 1.2 2.7e-26 92.0 1.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CBY08045.1 - 3.2e-07 30.6 0.3 3.8e-07 30.4 0.3 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Neur_chan_LBD PF02931.23 CBY08048.1 - 9.4e-53 178.8 4.2 1.6e-52 178.1 4.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY08048.1 - 1e-38 133.7 15.6 4.2e-33 115.4 10.6 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region NCBP3 PF10309.9 CBY08050.1 - 0.011 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 ATP-gua_Ptrans PF00217.19 CBY08051.1 - 4.3e-231 761.6 0.0 1.6e-56 191.2 0.0 4.3 4 0 0 4 4 4 4 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY08051.1 - 1.3e-102 336.2 0.4 6e-24 84.2 0.0 4.6 4 0 0 4 4 4 4 ATP:guanido phosphotransferase, N-terminal domain I-set PF07679.16 CBY08051.1 - 1.3e-07 31.6 0.6 0.00014 21.9 0.1 3.8 3 0 0 3 3 3 1 Immunoglobulin I-set domain Nif11 PF07862.11 CBY08051.1 - 0.00011 22.4 2.2 20 5.6 0.0 6.0 7 0 0 7 7 7 2 Nif11 domain tRNA-synt_2 PF00152.20 CBY08051.1 - 0.002 17.3 1.3 3.6 6.6 0.0 3.7 4 0 0 4 4 4 2 tRNA synthetases class II (D, K and N) Ig_3 PF13927.6 CBY08051.1 - 0.0026 18.3 0.1 0.47 11.1 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain MTCP1 PF08991.10 CBY08051.1 - 0.052 13.8 1.4 1.4e+02 2.8 0.0 4.2 4 0 0 4 4 4 0 Mature-T-Cell Proliferation I type KxDL PF10241.9 CBY08051.1 - 1 9.7 4.2 31 4.9 0.3 4.0 4 0 0 4 4 4 0 Uncharacterized conserved protein CBM_14 PF01607.24 CBY08053.1 - 1.1e-20 73.6 72.7 3.7e-05 23.8 1.1 8.9 6 3 2 8 8 8 7 Chitin binding Peritrophin-A domain ORF6C PF10552.9 CBY08054.1 - 0.056 13.5 0.8 0.056 13.5 0.8 2.3 1 1 1 2 2 2 0 ORF6C domain FapA PF03961.13 CBY08054.1 - 0.69 8.5 8.2 0.89 8.1 8.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FAM76 PF16046.5 CBY08054.1 - 0.73 9.1 10.0 0.84 8.9 10.0 1.1 1 0 0 1 1 1 0 FAM76 protein FUSC PF04632.12 CBY08054.1 - 2.6 6.5 5.8 3.3 6.1 5.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family EMP24_GP25L PF01105.24 CBY08054.1 - 5.6 6.9 7.3 14 5.6 7.3 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PDZ_6 PF17820.1 CBY08056.1 - 5.3e-23 80.6 2.1 2.5e-11 43.3 0.3 2.8 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 CBY08056.1 - 1.4e-22 79.9 3.1 2.4e-11 43.8 0.1 3.5 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 CBY08056.1 - 1e-08 35.4 3.3 0.00056 20.2 0.0 3.3 3 0 0 3 3 3 2 PDZ domain PLAC8 PF04749.17 CBY08057.1 - 0.03 15.3 1.9 0.048 14.7 1.9 1.5 1 1 0 1 1 1 0 PLAC8 family SRP14 PF02290.15 CBY08059.1 - 2e-15 56.9 0.1 2.9e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF1356 PF07092.12 CBY08060.1 - 8.9e-40 136.4 0.3 1.2e-39 136.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 CBY08060.1 - 0.026 15.0 0.0 0.057 14.0 0.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein Actin PF00022.19 CBY08061.1 - 2.1e-70 237.4 0.0 2.5e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Actin DUF5578 PF17741.1 CBY08063.1 - 3.3e-38 131.6 0.2 3.8e-38 131.4 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5578) Pkinase PF00069.25 CBY08064.1 - 5e-73 245.7 0.1 7.3e-73 245.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08064.1 - 3.9e-45 154.2 0.0 5.8e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CBY08064.1 - 5e-19 67.8 0.0 9.1e-19 67.0 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CBY08064.1 - 6.7e-09 35.5 0.1 1.1e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBY08064.1 - 3.4e-05 23.5 1.5 9.6e-05 22.1 1.5 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBY08064.1 - 0.00017 21.1 0.7 0.00036 20.0 0.7 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY08064.1 - 0.025 13.5 0.1 0.046 12.6 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 CBY08064.1 - 0.091 11.6 0.4 0.14 11.0 0.4 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 CBY08064.1 - 0.12 12.3 0.1 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mitofilin PF09731.9 CBY08064.1 - 3.2 6.5 7.1 4.6 5.9 7.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein EAF PF09816.9 CBY08065.1 - 9.6e-08 32.4 0.0 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DNA_pol_phi PF04931.13 CBY08065.1 - 1.5 6.9 10.2 1.6 6.7 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CBY08065.1 - 9.1 5.5 8.1 11 5.2 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein BET PF17035.5 CBY08066.1 - 0.032 14.4 1.7 0.089 13.0 0.1 2.4 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation RNA_polI_A14 PF08203.11 CBY08066.1 - 0.15 12.8 0.5 0.39 11.5 0.5 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF3928 PF13065.6 CBY08067.1 - 0.012 16.4 0.0 0.63 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3928) Y_phosphatase3 PF13350.6 CBY08068.1 - 0.00069 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family TFA2_Winged_2 PF18121.1 CBY08068.1 - 0.0083 15.8 0.3 3.1 7.6 0.0 3.4 2 1 1 3 3 3 1 TFA2 Winged helix domain 2 IpgD PF05925.12 CBY08068.1 - 0.038 12.6 0.0 0.062 11.9 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD XPC-binding PF09280.11 CBY08069.1 - 0.2 11.4 0.4 0.43 10.4 0.4 1.5 1 0 0 1 1 1 0 XPC-binding domain Lectin_C PF00059.21 CBY08071.1 - 9.5e-17 61.7 0.0 1.8e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain Laminin_G_3 PF13385.6 CBY08071.1 - 0.0042 17.2 0.0 0.026 14.7 0.0 2.0 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily UL45 PF05473.12 CBY08071.1 - 0.0065 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Pentaxin PF00354.17 CBY08071.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Pentaxin family AA_permease_2 PF13520.6 CBY08073.1 - 1e-56 192.6 47.4 1.3e-56 192.2 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY08073.1 - 9.1e-35 120.2 39.5 1.3e-34 119.6 39.5 1.2 1 0 0 1 1 1 1 Amino acid permease Rhodanese PF00581.20 CBY08074.1 - 3.7e-11 43.5 0.0 4.4e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain Dehalogenase PF13486.6 CBY08074.1 - 0.0081 15.6 0.0 0.0098 15.3 0.0 1.0 1 0 0 1 1 1 1 Reductive dehalogenase subunit BTD PF09270.10 CBY08076.1 - 2.6e-12 47.2 0.0 4.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain Ank_2 PF12796.7 CBY08077.1 - 4e-73 242.0 19.2 3e-15 56.6 0.0 9.4 3 2 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY08077.1 - 2.7e-68 225.5 16.7 2.7e-10 40.6 0.1 12.4 6 3 7 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY08077.1 - 2.1e-51 171.3 17.4 7.8e-10 38.8 0.1 11.4 4 3 8 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY08077.1 - 9.9e-48 154.6 9.7 0.00036 20.7 0.0 15.9 16 0 0 16 16 16 10 Ankyrin repeat Ank PF00023.30 CBY08077.1 - 2.7e-47 157.2 19.8 4.9e-06 26.7 0.0 14.7 15 0 0 15 15 15 10 Ankyrin repeat Ion_trans PF00520.31 CBY08077.1 - 7.1e-16 58.2 23.3 1.8e-15 56.8 23.4 1.6 1 1 0 1 1 1 1 Ion transport protein DUF2730 PF10805.8 CBY08077.1 - 0.071 13.2 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) PKD_channel PF08016.12 CBY08077.1 - 0.094 11.4 19.3 0.11 11.2 10.6 2.3 1 1 1 2 2 2 0 Polycystin cation channel Ank_4 PF13637.6 CBY08078.1 - 3.7e-32 110.3 11.1 3e-10 40.4 0.1 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY08078.1 - 6e-32 110.1 2.4 2e-08 34.7 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY08078.1 - 6.6e-25 86.9 7.3 2.5e-06 27.7 0.1 6.4 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 CBY08078.1 - 4.6e-24 83.8 6.5 0.0029 18.0 0.6 7.4 7 1 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 CBY08078.1 - 5.7e-22 75.4 5.6 0.0022 18.3 0.2 8.6 9 1 0 9 9 9 4 Ankyrin repeat DUF3447 PF11929.8 CBY08078.1 - 0.14 12.2 0.4 1.9 8.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Aminotran_1_2 PF00155.21 CBY08079.1 - 2.3e-39 135.6 0.0 3.2e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBY08079.1 - 0.0004 19.8 0.0 0.00074 18.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Trypsin PF00089.26 CBY08080.1 - 8.5e-61 205.6 1.3 9.6e-61 205.4 1.3 1.0 1 0 0 1 1 1 1 Trypsin Ion_trans_N PF08412.10 CBY08080.1 - 0.13 11.9 0.2 0.35 10.5 0.1 1.7 2 0 0 2 2 2 0 Ion transport protein N-terminal Kelch_2 PF07646.15 CBY08081.1 - 0.00018 21.4 1.5 1.5 8.9 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Silic_transp PF03842.13 CBY08081.1 - 0.012 14.0 0.4 0.019 13.3 0.4 1.3 1 0 0 1 1 1 0 Silicon transporter HKR_ArcB_TM PF18415.1 CBY08081.1 - 0.17 12.7 2.6 0.41 11.5 2.6 1.6 1 0 0 1 1 1 0 Histidine kinase receptor ArcB trans-membrane domain NIDO PF06119.14 CBY08082.1 - 0.0064 17.4 0.1 0.022 15.7 0.1 2.0 1 1 0 1 1 1 1 Nidogen-like Aminotran_3 PF00202.21 CBY08083.1 - 6e-86 288.6 0.0 7e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase_Tyr PF07714.17 CBY08084.1 - 4.9e-47 160.4 0.0 6.1e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY08084.1 - 8.1e-25 87.7 0.0 9.8e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY08084.1 - 0.00038 19.4 0.0 0.00052 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY08084.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY08084.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Galactosyl_T PF01762.21 CBY08085.1 - 3.8e-15 56.2 0.1 4.7e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 CBY08085.1 - 0.05 13.0 0.6 0.084 12.3 0.6 1.4 1 0 0 1 1 1 0 Fringe-like 7tm_1 PF00001.21 CBY08086.1 - 8.7e-33 113.8 12.3 1.2e-32 113.3 12.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CUB PF00431.20 CBY08087.1 - 7.4e-07 29.5 0.1 1.5e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 CUB domain DUF2420 PF10336.9 CBY08087.1 - 0.022 14.7 0.2 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) RXLR PF16810.5 CBY08087.1 - 0.1 13.1 1.5 0.22 12.0 1.5 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Tir_receptor_C PF07489.11 CBY08087.1 - 0.14 12.1 1.6 0.19 11.7 1.0 1.6 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.17 CBY08087.1 - 0.5 10.4 9.8 0.84 9.6 9.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 CBY08087.1 - 4.2 7.3 9.2 8.1 6.4 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) EMP24_GP25L PF01105.24 CBY08088.1 - 1.7e-12 47.7 0.1 2e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sushi PF00084.20 CBY08089.1 - 1.2e-05 25.8 4.8 0.0015 19.1 3.1 2.7 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) CUB PF00431.20 CBY08089.1 - 0.0027 18.0 0.0 0.015 15.6 0.0 2.3 1 1 0 1 1 1 1 CUB domain Trypan_PARP PF05887.11 CBY08089.1 - 0.14 12.1 5.2 0.36 10.8 5.2 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PP2C_C PF07830.13 CBY08089.1 - 0.39 11.2 3.1 1.1 9.8 3.1 1.7 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Mucin PF01456.17 CBY08089.1 - 0.71 9.9 22.2 1.3 9.0 22.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein RVT_1 PF00078.27 CBY08090.1 - 4e-16 59.2 0.0 8.9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY08090.1 - 4.8e-13 49.4 0.0 1.5e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY08090.1 - 1.3e-09 38.0 0.3 2.2e-08 34.1 0.0 2.9 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CBY08090.1 - 4.9e-05 23.3 1.0 0.00016 21.6 0.4 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H3C2 PF16721.5 CBY08090.1 - 0.028 14.8 0.3 0.15 12.4 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding zf-H2C2 PF09337.10 CBY08090.1 - 0.033 14.4 0.3 0.1 12.8 0.3 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DNA_pol_viral_C PF00336.18 CBY08090.1 - 0.042 13.3 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVP PF00077.20 CBY08090.1 - 0.098 13.0 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 CBY08091.1 - 5.3e-29 100.6 0.0 4.4e-28 97.6 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY08091.1 - 4.4e-27 94.0 0.0 1.4e-26 92.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY08091.1 - 4.6e-14 52.6 0.1 1.6e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-CCCH_4 PF18044.1 CBY08092.1 - 8.7e-05 22.2 3.2 0.00013 21.6 3.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBY08092.1 - 0.00019 22.1 3.8 0.00023 21.8 0.3 2.6 2 1 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 CBY08092.1 - 0.00046 20.0 3.0 0.00071 19.4 3.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY08092.1 - 0.0016 18.4 7.2 0.0027 17.7 7.2 1.4 1 0 0 1 1 1 1 Zinc finger domain Mt_ATP-synt_B PF05405.14 CBY08092.1 - 0.0026 17.4 5.4 0.0093 15.6 1.3 2.3 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-CCCH_3 PF15663.5 CBY08092.1 - 0.069 13.4 0.2 0.18 12.0 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger containing family Rubis-subs-bind PF09273.11 CBY08092.1 - 0.073 13.8 2.3 0.08 13.6 0.2 2.1 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding zf-C3H1 PF10650.9 CBY08092.1 - 0.083 12.6 1.5 0.13 12.0 1.5 1.3 1 0 0 1 1 1 0 Putative zinc-finger domain Syntaxin PF00804.25 CBY08092.1 - 0.19 11.4 5.8 4.1 7.0 0.2 2.3 2 0 0 2 2 2 0 Syntaxin APG6_N PF17675.1 CBY08092.1 - 3.4 8.2 6.7 1.1 9.8 2.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region EGF_3 PF12947.7 CBY08093.1 - 1.3e-51 172.4 145.8 3.3e-07 30.4 13.1 10.7 9 1 1 10 10 10 10 EGF domain EGF_MSP1_1 PF12946.7 CBY08093.1 - 2.8e-24 84.8 126.2 8.4e-06 25.7 7.4 10.4 9 1 1 10 10 10 9 MSP1 EGF domain 1 EGF_CA PF07645.15 CBY08093.1 - 3.5e-20 71.9 146.5 0.0067 16.6 6.8 10.5 9 1 1 10 10 10 10 Calcium-binding EGF domain EGF PF00008.27 CBY08093.1 - 4.6e-18 65.2 123.4 0.0082 16.4 3.4 10.6 9 1 1 10 10 10 10 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY08093.1 - 0.00037 20.8 11.0 0.0024 18.1 2.1 10.4 8 2 2 10 10 10 4 Pvs28 EGF domain cEGF PF12662.7 CBY08093.1 - 0.001 18.9 94.6 0.037 14.0 1.2 11.1 10 0 0 10 10 10 6 Complement Clr-like EGF-like hEGF PF12661.7 CBY08093.1 - 0.04 14.5 112.6 0.27 11.9 5.3 11.8 12 0 0 12 12 12 0 Human growth factor-like EGF Toprim_2 PF13155.6 CBY08093.1 - 0.076 13.4 0.1 0.22 11.9 0.1 1.8 1 0 0 1 1 1 0 Toprim-like Leu_zip PF15294.6 CBY08093.1 - 0.095 12.2 0.9 11 5.4 0.2 2.1 2 0 0 2 2 2 0 Leucine zipper EGF_3 PF12947.7 CBY08094.1 - 8e-39 131.5 144.8 1.2e-06 28.6 13.1 10.3 10 0 0 10 10 10 9 EGF domain EGF_MSP1_1 PF12946.7 CBY08094.1 - 2e-14 53.3 120.4 1.2e-06 28.5 7.7 10.6 10 0 0 10 10 10 6 MSP1 EGF domain 1 EGF PF00008.27 CBY08094.1 - 3.5e-10 40.0 118.1 0.004 17.4 5.7 10.2 9 1 0 9 9 9 6 EGF-like domain EGF_CA PF07645.15 CBY08094.1 - 8e-07 29.2 139.9 0.0033 17.6 4.5 10.3 10 1 0 10 10 10 6 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 CBY08094.1 - 0.00096 19.4 11.7 0.0016 18.7 2.2 9.7 9 0 0 9 9 9 5 Pvs28 EGF domain DBINO PF13892.6 CBY08094.1 - 0.0056 17.0 1.9 0.0088 16.4 1.9 1.2 1 0 0 1 1 1 1 DNA-binding domain bZIP_1 PF00170.21 CBY08094.1 - 0.082 13.0 2.1 0.13 12.3 2.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor cEGF PF12662.7 CBY08094.1 - 1.2 9.1 88.2 0.34 10.9 0.2 11.0 10 2 0 10 10 10 0 Complement Clr-like EGF-like eIF_4EBP PF05456.11 CBY08095.1 - 2.3e-27 95.2 0.4 2.4e-27 95.1 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Ribosomal_60s PF00428.19 CBY08095.1 - 0.0078 16.8 0.4 0.0078 16.8 0.4 1.5 2 0 0 2 2 2 1 60s Acidic ribosomal protein Trypsin PF00089.26 CBY08096.1 - 8.4e-41 140.2 0.6 1.3e-40 139.5 0.6 1.3 1 0 0 1 1 1 1 Trypsin EGF PF00008.27 CBY08096.1 - 2.3e-06 27.8 32.5 3.7e-05 23.9 8.2 4.6 3 0 0 3 3 3 3 EGF-like domain Trypsin_2 PF13365.6 CBY08096.1 - 0.00033 21.6 0.0 0.00084 20.3 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain hEGF PF12661.7 CBY08096.1 - 0.0043 17.6 7.2 0.0043 17.6 7.2 5.9 5 1 0 5 5 5 1 Human growth factor-like EGF DUF1986 PF09342.11 CBY08096.1 - 0.028 14.8 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) RRS1 PF04939.12 CBY08097.1 - 5e-45 153.3 10.5 5e-45 153.3 10.5 2.3 3 0 0 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) YscJ_FliF PF01514.17 CBY08097.1 - 0.35 10.5 6.0 4.2 7.0 0.2 2.6 3 0 0 3 3 3 0 Secretory protein of YscJ/FliF family Nup54 PF13874.6 CBY08098.1 - 2.9e-37 127.9 6.5 2.9e-37 127.9 6.5 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CBY08098.1 - 9.6e-09 36.0 68.4 5.2e-05 24.0 36.0 3.2 1 1 2 3 3 3 2 Nucleoporin FG repeat region Nup54_C PF18437.1 CBY08098.1 - 0.00048 20.0 0.6 0.001 18.9 0.6 1.6 1 0 0 1 1 1 1 Nup54 C-terminal interacting domain Fib_alpha PF08702.10 CBY08098.1 - 0.16 12.2 7.3 0.95 9.6 0.3 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RB_A PF01858.17 CBY08098.1 - 0.44 10.3 3.6 1.1 9.0 3.6 1.7 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain DZF PF07528.14 CBY08099.1 - 1.2e-50 172.5 0.1 1.6e-50 172.1 0.1 1.1 1 0 0 1 1 1 1 DZF domain AAA_32 PF13654.6 CBY08099.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Gly-rich_Ago1 PF12764.7 CBY08099.1 - 0.65 10.8 4.9 1.8 9.4 4.9 1.7 1 0 0 1 1 1 0 Glycine-rich region of argonaut Tnp_zf-ribbon_2 PF13842.6 CBY08100.1 - 0.01 16.6 0.5 0.022 15.6 0.5 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DMRT-like PF15791.5 CBY08100.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 Tap-RNA_bind PF09162.10 CBY08102.1 - 0.066 13.1 0.2 2.9 7.8 0.1 2.5 1 1 1 2 2 2 0 Tap, RNA-binding Tap-RNA_bind PF09162.10 CBY08103.1 - 0.022 14.6 1.3 4 7.4 0.1 3.4 2 1 1 3 3 3 0 Tap, RNA-binding Phospholip_A2_1 PF00068.19 CBY08104.1 - 1e-14 55.0 9.3 1.5e-14 54.4 9.3 1.2 1 0 0 1 1 1 1 Phospholipase A2 Ion_trans_2 PF07885.16 CBY08105.1 - 6.9e-31 106.0 15.0 3e-17 62.3 1.8 4.0 4 0 0 4 4 4 3 Ion channel Ion_trans PF00520.31 CBY08105.1 - 0.0029 16.9 10.0 0.004 16.4 5.8 2.7 1 1 0 2 2 2 1 Ion transport protein IRK PF01007.20 CBY08105.1 - 0.081 12.7 1.8 0.43 10.4 0.2 2.7 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain Ac76 PF05814.11 CBY08105.1 - 0.53 10.3 6.1 0.46 10.5 0.1 2.9 2 0 0 2 2 2 0 Orf76 (Ac76) Ig_3 PF13927.6 CBY08106.1 - 1.2e-19 70.7 0.1 4.5e-15 56.0 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY08106.1 - 3.5e-14 52.6 0.2 1.3e-10 41.2 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY08106.1 - 4.8e-13 49.3 0.0 1.9e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CBY08106.1 - 2.5e-09 37.2 0.1 4.3e-07 30.0 0.0 3.1 2 2 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CBY08106.1 - 1.8e-05 24.8 0.0 0.00048 20.3 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY08106.1 - 0.013 15.5 0.1 0.26 11.4 0.0 2.6 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain TIM21 PF08294.11 CBY08106.1 - 0.054 13.4 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 TIM21 Ig_6 PF18452.1 CBY08106.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Podoplanin PF05808.11 CBY08106.1 - 0.12 12.4 6.5 0.27 11.3 6.5 1.6 1 1 0 1 1 1 0 Podoplanin DUF5326 PF17260.2 CBY08106.1 - 0.29 11.3 7.2 0.099 12.8 4.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5326) DUF4490 PF14892.6 CBY08107.1 - 0.0036 17.3 0.8 0.0097 15.9 0.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4490) Pes-10 PF07149.11 CBY08107.1 - 0.19 10.7 3.3 0.25 10.4 3.3 1.1 1 0 0 1 1 1 0 Pes-10 Kelch_6 PF13964.6 CBY08108.1 - 3.5e-08 33.4 0.6 0.48 10.8 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CBY08108.1 - 0.019 14.5 0.1 0.34 10.5 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 CBY08108.1 - 0.066 13.2 0.1 2.9 8.0 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain ASC PF00858.24 CBY08109.1 - 2.4e-35 122.4 9.7 2.8e-35 122.2 9.7 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel LIM PF00412.22 CBY08110.1 - 1.7e-30 105.0 43.1 3.6e-11 43.1 9.0 3.2 3 0 0 3 3 3 3 LIM domain CAP_N PF01213.19 CBY08110.1 - 0.038 13.5 2.9 0.056 12.9 2.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1179 PF06678.11 CBY08110.1 - 0.42 10.6 5.6 0.92 9.5 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) BORCS6 PF10157.9 CBY08110.1 - 0.87 9.8 4.5 1.3 9.2 4.1 1.4 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Lin-8 PF03353.15 CBY08110.1 - 2.3 7.7 4.4 3.3 7.2 4.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mito_fiss_reg PF05308.11 CBY08110.1 - 8.7 6.3 10.6 9.4 6.2 9.3 1.6 1 1 1 2 2 2 0 Mitochondrial fission regulator zf-rbx1 PF12678.7 CBY08112.1 - 2.5e-14 53.3 8.6 3.2e-14 53.0 8.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY08112.1 - 3.7e-11 42.9 4.3 4.4e-11 42.7 4.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBY08112.1 - 0.0022 18.3 10.8 0.0044 17.3 10.8 1.7 1 1 0 1 1 1 1 Ring finger domain PHD PF00628.29 CBY08112.1 - 0.023 14.6 7.3 0.035 14.0 7.3 1.4 1 1 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 CBY08112.1 - 0.045 13.9 6.0 0.084 13.1 5.9 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain IRK_C PF17655.1 CBY08112.1 - 0.055 13.1 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain gp32 PF08804.10 CBY08112.1 - 0.077 13.0 0.3 0.096 12.7 0.3 1.2 1 0 0 1 1 1 0 gp32 DNA binding protein like zf-C3HC4_2 PF13923.6 CBY08112.1 - 0.29 11.0 10.1 1.5 8.7 10.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY08112.1 - 0.29 11.2 8.5 0.64 10.1 8.5 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY08112.1 - 1.8 8.5 10.8 8.6 6.3 10.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 CBY08113.1 - 1.7e-43 148.9 0.0 2.5e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08113.1 - 3.9e-19 68.9 0.0 7.2e-19 68.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2362 PF10154.9 CBY08114.1 - 0.0076 15.3 1.7 0.011 14.7 1.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) Topoisom_I_N PF02919.15 CBY08114.1 - 0.51 9.8 3.4 0.94 8.9 3.4 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Forkhead PF00250.18 CBY08115.1 - 5.4e-37 125.9 1.6 1.1e-36 125.0 0.8 2.0 2 0 0 2 2 2 1 Forkhead domain Galactosyl_T PF01762.21 CBY08116.1 - 6.1e-17 62.1 0.0 7.5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase CobW_C PF07683.14 CBY08116.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Trm5_N PF18093.1 CBY08117.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain Adeno_terminal PF02459.15 CBY08117.1 - 0.16 10.3 1.6 0.2 10.0 1.6 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Astacin PF01400.24 CBY08119.1 - 4.6e-23 81.8 0.0 9.5e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY08119.1 - 1.8e-18 66.4 63.1 2.6e-06 27.5 10.7 6.7 6 0 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.7 CBY08119.1 - 1.1e-09 38.0 32.9 0.0004 20.2 1.3 5.1 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY08119.1 - 4.9e-09 36.2 23.7 1.4e-07 31.6 13.2 5.6 5 0 0 5 5 5 2 EGF domain EGF PF00008.27 CBY08119.1 - 1.9e-05 24.9 56.2 0.0024 18.1 8.3 6.2 5 1 0 5 5 5 3 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY08119.1 - 0.22 11.9 31.9 0.058 13.7 1.1 4.7 4 0 0 4 4 4 0 Pvs28 EGF domain hEGF PF12661.7 CBY08119.1 - 0.53 11.0 51.3 0.1 13.3 5.4 6.2 5 0 0 5 5 5 0 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY08119.1 - 1.5 9.2 57.0 0.13 12.5 3.7 5.6 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY08119.1 - 4.9 7.3 28.5 1 9.5 3.5 4.9 4 0 0 4 4 4 0 MSP1 EGF domain 1 AF-4 PF05110.13 CBY08120.1 - 0.018 13.2 0.7 0.021 12.9 0.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RVT_1 PF00078.27 CBY08121.1 - 8.3e-17 61.4 0.0 3.5e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CBY08121.1 - 8.9e-14 51.3 0.0 1.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY08121.1 - 0.0042 17.4 0.0 0.0092 16.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CBY08121.1 - 0.0066 17.0 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TACC_C PF05010.14 CBY08121.1 - 0.045 13.5 0.3 0.084 12.7 0.3 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal COPIIcoated_ERV PF07970.12 CBY08122.1 - 0.00046 20.1 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Molybdopterin PF00384.22 CBY08123.1 - 3.2e-62 210.9 0.0 7.7e-61 206.3 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CBY08123.1 - 1.5e-20 73.0 0.5 3e-20 72.1 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 CBY08123.1 - 5.6e-17 61.0 0.3 5.6e-17 61.0 0.3 2.1 3 0 0 3 3 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 CBY08123.1 - 5.9e-10 39.0 0.6 5.9e-10 39.0 0.6 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 CBY08123.1 - 0.015 15.1 5.1 0.74 9.7 1.9 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Lyx_isomer PF07385.12 CBY08123.1 - 0.033 13.4 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase Fer4_16 PF13484.6 CBY08123.1 - 0.047 14.6 2.9 17 6.4 2.6 2.9 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CBY08123.1 - 0.39 10.9 5.5 1.9 8.6 5.5 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBY08123.1 - 0.43 11.2 6.1 0.54 10.9 3.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 CBY08123.1 - 4.8 7.8 9.4 1 10.0 3.1 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBY08123.1 - 5.8 7.4 8.6 21 5.6 8.6 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBY08123.1 - 9.1 6.9 8.6 0.83 10.2 3.3 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Sec15 PF04091.12 CBY08125.1 - 3.5e-53 181.1 2.2 3.8e-53 180.9 0.8 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like NPF PF16601.5 CBY08125.1 - 1.9 8.9 12.9 1.6 9.1 6.8 2.2 1 1 1 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif COPIIcoated_ERV PF07970.12 CBY08126.1 - 5.3e-35 121.3 0.5 9.2e-35 120.5 0.5 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBY08126.1 - 3.8e-29 100.9 0.1 1.2e-28 99.3 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Arfaptin PF06456.13 CBY08127.1 - 1.1e-39 136.3 3.5 1.1e-39 136.3 3.5 2.0 2 0 0 2 2 2 1 Arfaptin-like domain PDZ_6 PF17820.1 CBY08127.1 - 2.6e-09 36.8 0.0 1.1e-08 34.8 0.0 2.1 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 CBY08127.1 - 6.5e-09 36.0 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY08127.1 - 9.6e-06 25.8 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF1013 PF06242.11 CBY08127.1 - 0.018 15.1 0.7 0.057 13.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) MFS_1 PF07690.16 CBY08129.1 - 5.9e-53 180.0 32.9 2e-50 171.7 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CBY08129.1 - 0.0023 16.3 4.1 0.0023 16.3 4.1 3.1 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family SepRS_C PF18006.1 CBY08130.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA synthetase C-terminal domain Troponin PF00992.20 CBY08131.1 - 1.2e-18 67.7 27.0 1.2e-18 67.7 27.0 2.3 1 1 1 2 2 2 2 Troponin Fasciclin PF02469.22 CBY08131.1 - 0.08 13.2 0.2 0.56 10.4 0.1 2.1 2 0 0 2 2 2 0 Fasciclin domain EBP50_C PF09007.11 CBY08131.1 - 0.22 12.5 5.5 0.35 11.9 5.5 1.3 1 0 0 1 1 1 0 EBP50, C-terminal PMP22_Claudin PF00822.20 CBY08132.1 - 0.0019 18.1 0.4 0.014 15.3 0.4 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY08132.1 - 0.0053 17.0 0.2 1.4 9.1 0.0 2.4 2 1 0 2 2 2 2 Lipoma HMGIC fusion partner-like protein DctM PF06808.12 CBY08132.1 - 0.0063 15.4 0.4 0.0086 14.9 0.4 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Claudin_2 PF13903.6 CBY08132.1 - 0.0095 15.7 3.2 0.27 10.9 3.2 2.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Trypan_PARP PF05887.11 CBY08132.1 - 0.028 14.4 5.5 0.17 11.8 0.3 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3439 PF11921.8 CBY08133.1 - 0.00018 21.5 27.6 0.0099 15.8 4.9 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3439) Hyphal_reg_CWP PF11765.8 CBY08133.1 - 0.002 17.1 0.7 0.4 9.6 0.1 2.2 2 0 0 2 2 2 2 Hyphally regulated cell wall protein N-terminal Mucin2_WxxW PF13330.6 CBY08133.1 - 3.9 8.4 10.1 3.3 8.6 0.1 3.8 3 1 0 3 3 3 0 Mucin-2 protein WxxW repeating region DUF5478 PF17572.2 CBY08133.1 - 7 6.8 8.0 6 7.1 0.2 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5478) Sugar_tr PF00083.24 CBY08134.1 - 8.9e-28 97.3 25.9 1.3e-27 96.8 25.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY08134.1 - 2.1e-22 79.6 26.6 2.1e-22 79.6 26.6 2.4 3 0 0 3 3 3 1 Major Facilitator Superfamily UCR_6-4kD PF08997.10 CBY08134.1 - 0.0029 17.5 3.4 0.16 11.9 0.3 4.2 4 0 0 4 4 4 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein BORCS6 PF10157.9 CBY08135.1 - 2.3e-12 47.4 3.6 2.7e-12 47.2 3.6 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Laminin_II PF06009.12 CBY08135.1 - 0.0055 16.7 1.5 0.0076 16.3 0.8 1.6 1 1 1 2 2 2 1 Laminin Domain II DUF3616 PF12275.8 CBY08135.1 - 0.032 13.7 0.2 0.042 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) Cue1_U7BR PF18499.1 CBY08135.1 - 0.05 13.6 1.5 0.076 13.1 0.2 2.0 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 Amino_oxidase PF01593.24 CBY08136.1 - 8.8e-14 51.6 0.0 4.9e-10 39.3 0.0 2.4 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CBY08136.1 - 7.9e-12 45.2 0.1 1.5e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CBY08136.1 - 0.0085 15.7 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Prenylcys_lyase PF07156.14 CBY08136.1 - 0.01 14.9 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 Prenylcysteine lyase FAD_binding_3 PF01494.19 CBY08136.1 - 0.072 12.3 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 CBY08136.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CBY08136.1 - 0.12 12.3 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CBY08136.1 - 0.16 11.2 0.3 0.41 9.8 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phospholip_A2_1 PF00068.19 CBY08137.1 - 4e-17 62.7 6.0 4e-17 62.7 6.0 1.5 2 0 0 2 2 2 1 Phospholipase A2 F-box-like PF12937.7 CBY08138.1 - 2e-05 24.4 0.0 8.3e-05 22.4 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY08138.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 F-box domain ANAPC4_WD40 PF12894.7 CBY08139.1 - 1.1e-08 35.2 0.1 0.00027 21.2 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY08139.1 - 4.8e-08 33.5 12.7 0.014 16.2 0.2 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat PD40 PF07676.12 CBY08139.1 - 0.017 15.1 0.1 0.75 9.8 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF1951 PF09188.10 CBY08140.1 - 0.027 14.5 0.2 0.059 13.4 0.1 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF1951) TPR_2 PF07719.17 CBY08142.1 - 4.5e-25 85.7 17.4 1.3e-05 24.9 0.9 9.8 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBY08142.1 - 1.5e-22 78.3 2.6 0.013 16.3 0.0 10.0 7 2 3 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 CBY08142.1 - 2e-21 76.3 7.9 6.2e-06 26.6 0.1 7.0 5 2 1 6 6 6 4 Tetratricopeptide repeat DUF1736 PF08409.11 CBY08142.1 - 3.3e-21 75.1 0.8 3.3e-21 75.1 0.8 2.4 3 0 0 3 3 2 1 Domain of unknown function (DUF1736) TPR_11 PF13414.6 CBY08142.1 - 1.3e-20 72.8 9.6 1.2e-07 31.3 0.1 7.1 7 0 0 7 7 7 4 TPR repeat TPR_16 PF13432.6 CBY08142.1 - 4e-19 69.0 0.0 0.064 13.9 0.1 6.2 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 CBY08142.1 - 6.9e-19 66.8 7.4 0.1 13.1 0.0 9.6 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 CBY08142.1 - 1.2e-18 66.1 19.1 4.3e-05 23.1 0.4 8.3 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBY08142.1 - 3e-18 64.4 12.6 0.00026 21.0 0.3 8.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY08142.1 - 6.6e-17 61.6 16.7 1.6e-06 28.3 0.9 7.6 5 3 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBY08142.1 - 8e-10 38.0 10.4 0.018 15.1 0.1 7.1 8 1 0 8 8 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 CBY08142.1 - 1.2e-09 37.7 17.1 0.007 16.2 0.6 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY08142.1 - 1.9e-08 34.1 7.0 4.5e-08 32.9 1.9 2.7 3 0 0 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 CBY08142.1 - 1.8e-07 31.4 3.0 0.21 12.0 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY08142.1 - 2.4e-07 30.8 0.2 0.19 11.9 0.0 5.1 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY08142.1 - 7.5e-07 29.3 13.7 0.0081 16.4 0.0 6.4 4 2 3 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 CBY08142.1 - 7.4e-05 22.4 1.2 0.012 15.2 0.1 3.6 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 CBY08142.1 - 0.00026 21.4 16.1 0.38 11.5 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat PPR PF01535.20 CBY08142.1 - 0.011 15.9 0.1 4.8 7.7 0.0 4.5 4 0 0 4 4 4 0 PPR repeat Mad3_BUB1_I PF08311.12 CBY08142.1 - 0.044 13.8 6.6 0.25 11.3 2.4 3.7 3 1 0 3 3 3 0 Mad3/BUB1 homology region 1 HTH_Bact PF18768.1 CBY08142.1 - 1.5 8.4 6.0 22 4.7 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix bacterial domain MIT PF04212.18 CBY08142.1 - 5.2 7.2 12.1 3 8.0 0.3 4.7 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 CBY08142.1 - 5.8 7.0 17.4 0.4 10.7 0.4 4.6 6 0 0 6 6 3 0 Tetratricopeptide repeat Nucleoporin_FG PF13634.6 CBY08143.1 - 1.1 10.1 28.3 4.6 8.1 28.3 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region NPF PF16601.5 CBY08143.1 - 1.2 9.5 17.4 1.4 9.3 10.3 2.1 1 1 1 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif tRNA-synt_1d PF00750.19 CBY08147.1 - 1.1e-07 31.2 0.2 2.5e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CBY08147.1 - 1.1e-07 32.0 0.9 1.8e-07 31.4 0.1 1.8 2 1 0 2 2 2 1 DALR anticodon binding domain AdenylateSensor PF16579.5 CBY08147.1 - 0.081 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Adenylate sensor of SNF1-like protein kinase SPT16 PF08644.11 CBY08147.1 - 0.31 11.2 1.9 0.31 11.2 0.3 1.7 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) tRNA-synt_1d PF00750.19 CBY08148.1 - 7.6e-26 90.9 0.0 1.7e-25 89.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 CBY08148.1 - 0.024 14.0 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain SRPRB PF09439.10 CBY08149.1 - 1.7e-07 30.8 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit SRPRB PF09439.10 CBY08150.1 - 6.6e-29 100.6 0.3 8.2e-29 100.3 0.3 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CBY08150.1 - 3.1e-13 49.6 0.0 3.8e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY08150.1 - 6e-10 39.2 0.1 7.7e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY08150.1 - 2.6e-06 27.1 0.1 3.5e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 CBY08150.1 - 4.4e-05 23.7 0.0 5.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBY08150.1 - 0.00074 18.9 0.1 0.00088 18.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 CBY08150.1 - 0.0011 19.0 0.4 1 9.4 0.1 2.2 1 1 1 2 2 2 2 Dynamin family SRP54 PF00448.22 CBY08150.1 - 0.0017 18.1 0.4 0.013 15.1 0.4 2.0 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain GTP_EFTU PF00009.27 CBY08150.1 - 0.002 17.7 0.1 1.4 8.5 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CBY08150.1 - 0.0098 16.1 0.0 0.01 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 CBY08150.1 - 0.027 14.4 0.2 0.046 13.6 0.1 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.18 CBY08150.1 - 0.039 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PduV-EutP PF10662.9 CBY08150.1 - 0.054 13.2 1.5 0.74 9.6 0.2 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 CBY08150.1 - 0.079 12.5 0.1 0.098 12.2 0.1 1.1 1 0 0 1 1 1 0 Ras family TPR_12 PF13424.6 CBY08151.1 - 0.7 10.2 4.2 14 6.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY08151.1 - 1.2 9.4 3.9 32 5.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat NAC PF01849.18 CBY08152.1 - 2.2e-24 85.2 0.1 4e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 NAC domain Ufd2P_core PF10408.9 CBY08153.1 - 6.9e-107 358.6 9.9 1e-106 358.0 9.9 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CBY08153.1 - 2.2e-20 72.6 0.3 4.3e-20 71.7 0.3 1.5 1 0 0 1 1 1 1 U-box domain Pentapeptide PF00805.22 CBY08153.1 - 0.041 13.5 0.2 0.9 9.2 0.0 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Methyltransf_11 PF08241.12 CBY08154.1 - 2.3e-19 69.8 0.1 5.4e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY08154.1 - 2.4e-17 63.2 0.0 3.4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY08154.1 - 1.2e-15 57.6 0.1 3.4e-15 56.2 0.1 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY08154.1 - 1.8e-15 57.4 0.1 5.2e-15 55.9 0.1 1.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY08154.1 - 5.6e-13 49.5 0.1 9.5e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBY08154.1 - 3.6e-10 39.6 0.0 4.9e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 CBY08154.1 - 2e-09 37.4 0.1 2.8e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 CBY08154.1 - 1.6e-07 31.0 0.3 3.2e-07 30.0 0.1 1.5 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 CBY08154.1 - 5.4e-07 28.8 0.0 7.5e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 CBY08154.1 - 1.4e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 CBY08154.1 - 2.6e-05 23.7 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CBY08154.1 - 2.9e-05 23.7 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CBY08154.1 - 0.00024 21.1 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CBY08154.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 CBY08154.1 - 0.0073 15.9 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 CBY08154.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ank_4 PF13637.6 CBY08155.1 - 2.2e-16 60.0 0.5 4.7e-06 27.1 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY08155.1 - 4.5e-16 59.2 0.1 1.4e-06 28.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY08155.1 - 7.8e-14 50.4 0.0 9e-06 25.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY08155.1 - 1.3e-11 44.5 0.1 2.4e-05 24.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY08155.1 - 2.4e-11 43.6 0.6 0.00018 21.8 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat NTP_transferase PF00483.23 CBY08156.1 - 2.9e-29 102.4 0.0 4.1e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CBY08156.1 - 2.2e-08 33.5 4.2 2.1e-06 27.2 0.1 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CBY08156.1 - 3e-05 24.4 0.0 4.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CHGN PF05679.16 CBY08157.1 - 6.2e-39 134.2 0.0 7.7e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY08157.1 - 2.1e-07 30.5 0.3 4.9e-07 29.3 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY08157.1 - 0.0096 15.7 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF3788 PF12663.7 CBY08157.1 - 0.025 14.5 0.1 0.078 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) CHGN PF05679.16 CBY08158.1 - 3.4e-19 69.1 0.6 3.7e-19 69.0 0.6 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase bZIP_1 PF00170.21 CBY08159.1 - 9.5e-10 38.4 12.8 2.3e-09 37.2 12.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY08159.1 - 7.9e-07 29.1 17.4 4.2e-06 26.8 15.5 2.5 1 1 1 2 2 2 1 Basic region leucine zipper GIT_CC PF16559.5 CBY08159.1 - 0.036 13.9 3.8 0.11 12.4 3.8 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Peptidase_S30 PF01577.16 CBY08159.1 - 1.2 8.6 14.3 3 7.4 8.9 2.1 1 1 1 2 2 2 0 Potyvirus P1 protease Cnn_1N PF07989.11 CBY08159.1 - 1.7 8.9 10.7 0.18 12.0 3.8 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_Maf PF03131.17 CBY08159.1 - 1.8 9.1 21.1 0.13 12.8 16.0 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor LNP1 PF15419.6 CBY08159.1 - 5.4 7.2 13.7 11 6.2 13.7 1.7 1 1 0 1 1 1 0 Leukemia NUP98 fusion partner 1 ADIP PF11559.8 CBY08159.1 - 7.7 6.6 19.9 0.43 10.7 4.2 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SHIPPO-rpt PF07004.12 CBY08160.1 - 1.9e-17 63.3 19.6 7.6e-06 26.6 0.9 5.6 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat FH2 PF02181.23 CBY08162.1 - 4.7e-24 85.2 0.5 1e-23 84.1 0.1 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain PDZ PF00595.24 CBY08162.1 - 7.1e-13 48.7 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY08162.1 - 5.3e-09 35.8 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY08162.1 - 0.00015 22.0 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain CCM2_C PF16545.5 CBY08162.1 - 0.11 13.0 0.2 0.57 10.7 0.2 2.2 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology Cnd1 PF12717.7 CBY08162.1 - 0.11 12.5 0.8 5.3 7.1 0.1 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CHAD PF05235.14 CBY08162.1 - 2.2 8.2 6.0 1.5 8.8 0.3 2.5 2 1 0 2 2 2 0 CHAD domain WD40 PF00400.32 CBY08164.1 - 8.8e-52 172.0 10.2 3.3e-10 40.4 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY08164.1 - 1.2e-22 80.0 0.1 4.2e-05 23.8 0.0 5.9 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY08164.1 - 4.1e-10 39.5 0.3 0.0042 16.5 0.0 4.1 4 0 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CBY08164.1 - 7.2e-08 31.8 3.1 0.096 11.6 0.2 5.7 1 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY08164.1 - 4.1e-06 25.7 3.5 0.28 9.8 0.0 5.5 3 3 3 6 6 6 2 Nucleoporin Nup120/160 CEP19 PF14933.6 CBY08164.1 - 6.1e-06 26.6 0.5 9.2e-06 26.1 0.5 1.3 1 0 0 1 1 1 1 CEP19-like protein PALB2_WD40 PF16756.5 CBY08164.1 - 0.012 14.5 0.2 2.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain ELYS-bb PF16687.5 CBY08164.1 - 0.04 12.5 0.0 0.19 10.3 0.0 1.9 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin DUF5570 PF17731.1 CBY08164.1 - 0.046 13.8 0.5 0.34 11.0 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5570) PTH2 PF01981.16 CBY08165.1 - 1.8e-38 131.4 0.1 2.9e-38 130.8 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PLDc_2 PF13091.6 CBY08166.1 - 2.1e-15 56.8 0.1 1.2e-06 28.4 0.2 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CBY08166.1 - 0.00041 20.4 1.0 0.23 11.7 0.0 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif UPF0167 PF03691.14 CBY08166.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) HMG_box PF00505.19 CBY08167.1 - 1.1e-12 48.2 6.5 1.1e-12 48.2 6.5 4.2 2 1 1 3 3 3 1 HMG (high mobility group) box DUF4407 PF14362.6 CBY08167.1 - 8 5.7 19.3 16 4.7 19.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Abhydrolase_3 PF07859.13 CBY08168.1 - 7.4e-45 153.4 0.0 5e-35 121.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CBY08168.1 - 0.00015 20.7 0.0 0.00047 19.1 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 CBY08168.1 - 0.00072 18.5 0.0 0.12 11.2 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family LIDHydrolase PF10230.9 CBY08168.1 - 0.003 17.1 0.0 0.019 14.5 0.0 2.0 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 CBY08168.1 - 0.012 15.1 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family RNA_binding PF01877.17 CBY08169.1 - 0.11 12.8 0.8 0.29 11.4 0.8 1.8 1 0 0 1 1 1 0 RNA binding Glyco_hydro_1 PF00232.18 CBY08171.1 - 2.7e-135 451.3 6.0 3.1e-135 451.1 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 2OG-FeII_Oxy_3 PF13640.6 CBY08172.1 - 0.00038 21.3 0.0 0.0011 19.8 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FtsH_ext PF06480.15 CBY08177.1 - 0.0041 17.5 0.1 0.0056 17.0 0.1 1.2 1 0 0 1 1 1 1 FtsH Extracellular rve PF00665.26 CBY08178.1 - 3.4e-12 46.6 0.0 6.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CBY08178.1 - 0.012 15.8 0.1 0.025 14.8 0.1 1.6 1 0 0 1 1 1 0 DDE domain Hydrolase PF00702.26 CBY08179.1 - 3.7e-12 47.0 0.1 1.8e-06 28.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY08179.1 - 5e-05 23.2 0.1 0.00045 20.0 0.0 2.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY08180.1 - 1.2e-07 32.2 0.1 2e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Alpha-amylase PF00128.24 CBY08182.1 - 1.1e-75 255.3 1.0 1.8e-75 254.6 1.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 CBY08182.1 - 0.00098 18.6 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus RNA_pol_RpbG PF16992.5 CBY08183.1 - 0.017 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase, subunit G DUF1189 PF06691.11 CBY08183.1 - 0.024 14.2 1.0 0.029 14.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) MAS20 PF02064.15 CBY08184.1 - 0.94 9.6 7.9 0.13 12.4 3.1 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor DUF4481 PF14800.6 CBY08185.1 - 0.96 8.9 5.9 1.6 8.1 5.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4481) Aldose_epim PF01263.20 CBY08186.1 - 4.2e-49 167.5 0.7 4.9e-49 167.3 0.7 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PCMD PF13201.6 CBY08186.1 - 0.041 13.7 0.1 0.096 12.5 0.0 1.6 1 1 1 2 2 2 0 Putative carbohydrate metabolism domain Astacin PF01400.24 CBY08187.1 - 3.7e-13 49.5 0.1 1.7e-12 47.3 0.1 2.0 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY08187.1 - 6.7e-05 23.0 5.7 6.7e-05 23.0 5.7 3.6 3 0 0 3 3 3 1 Calcium-binding EGF domain Ldl_recept_a PF00057.18 CBY08187.1 - 0.022 14.9 2.9 0.022 14.9 2.9 4.5 3 1 1 4 4 4 0 Low-density lipoprotein receptor domain class A UPF0054 PF02130.17 CBY08187.1 - 0.16 11.8 0.6 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 I-set PF07679.16 CBY08188.1 - 7.7e-18 64.4 0.0 2.3e-17 62.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY08188.1 - 4.8e-11 43.1 0.1 2e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 CBY08188.1 - 4.3e-07 30.2 0.0 9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY08188.1 - 3e-06 27.3 0.4 8.7e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CBY08188.1 - 0.01 16.0 0.6 7 6.9 0.0 3.1 2 1 1 3 3 3 0 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY08188.1 - 0.017 15.2 0.2 0.078 13.0 0.0 2.2 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Spore_Cse60 PF10957.8 CBY08188.1 - 0.12 12.5 4.1 0.64 10.1 2.7 3.1 1 1 1 2 2 2 0 Sporulation protein Cse60 EF-hand_7 PF13499.6 CBY08190.1 - 5e-09 36.5 0.1 6.8e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY08190.1 - 2.3e-08 33.7 1.1 5e-08 32.7 1.1 1.7 1 1 0 1 1 1 1 EF-hand domain pair S_100 PF01023.19 CBY08190.1 - 8.3e-08 31.8 0.2 1.7e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 CBY08190.1 - 6.4e-07 28.5 1.7 2e-06 26.9 0.1 2.5 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 CBY08190.1 - 1.1e-05 24.7 0.1 7.1e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY08190.1 - 4e-05 23.2 0.0 0.001 18.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CBY08190.1 - 0.013 15.5 0.2 0.016 15.1 0.2 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY08190.1 - 0.025 14.9 0.1 0.032 14.6 0.1 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 CBY08190.1 - 0.061 13.3 0.3 0.078 12.9 0.3 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TerB DUF2680 PF10925.8 CBY08190.1 - 0.062 13.3 0.2 0.79 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Caleosin PF05042.13 CBY08190.1 - 0.12 12.3 1.9 1.2 9.0 0.4 2.0 1 1 1 2 2 2 0 Caleosin related protein SNF PF00209.18 CBY08191.1 - 6.7e-87 292.3 12.8 8.6e-87 292.0 12.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family OAM_alpha PF16552.5 CBY08192.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit Peptidase_M16_M PF16187.5 CBY08193.1 - 1.8e-13 50.4 0.0 3.7e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CBY08193.1 - 8.9e-05 22.6 0.2 0.0002 21.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain THP2 PF09432.10 CBY08193.1 - 0.055 13.5 0.5 3.8 7.6 0.0 2.8 2 1 0 2 2 2 0 Tho complex subunit THP2 Piezo_RRas_bdg PF12166.8 CBY08194.1 - 0.1 11.9 0.3 0.12 11.7 0.3 1.0 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Phospholip_A2_1 PF00068.19 CBY08196.1 - 3.7e-13 49.9 6.2 3.7e-13 49.9 6.2 2.2 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY08198.1 - 3.3e-14 53.3 7.1 3.3e-14 53.3 7.1 1.9 2 0 0 2 2 2 1 Phospholipase A2 Trypsin PF00089.26 CBY08199.1 - 6e-27 94.9 0.0 1e-26 94.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF4366 PF14283.6 CBY08199.1 - 0.053 13.6 1.1 0.071 13.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Shisa PF13908.6 CBY08199.1 - 0.078 13.2 1.4 0.13 12.5 1.4 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Menin PF05053.13 CBY08199.1 - 0.48 8.7 4.6 0.67 8.3 4.6 1.1 1 0 0 1 1 1 0 Menin Tubulin PF00091.25 CBY08200.1 - 5.9e-64 215.9 0.0 8e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY08200.1 - 1.6e-50 170.4 0.1 2.6e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY08200.1 - 0.00089 19.0 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Fic PF02661.18 CBY08201.1 - 6e-27 94.4 0.1 1.7e-26 93.0 0.1 1.8 1 0 0 1 1 1 1 Fic/DOC family TPR_1 PF00515.28 CBY08201.1 - 4e-06 26.4 0.0 0.032 14.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY08201.1 - 9.5e-06 25.4 0.0 0.026 14.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY08201.1 - 2.5e-05 24.7 0.0 0.028 15.2 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY08201.1 - 2.9e-05 24.5 0.1 8.4e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBY08201.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 CBY08201.1 - 0.0057 16.3 0.1 0.051 13.3 0.0 2.3 1 1 1 2 2 2 1 TPR repeat TPR_8 PF13181.6 CBY08201.1 - 0.023 14.9 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CBY08201.1 - 0.045 13.1 0.1 0.086 12.2 0.1 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_16 PF13432.6 CBY08201.1 - 0.1 13.3 0.0 0.62 10.8 0.0 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY08201.1 - 0.12 12.6 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4192 PF13830.6 CBY08201.1 - 0.24 11.4 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) zf-C3HC4_3 PF13920.6 CBY08202.1 - 9.7e-13 47.8 16.6 1.4e-12 47.2 16.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY08202.1 - 0.00039 20.2 15.6 0.00063 19.6 15.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY08202.1 - 0.54 10.3 17.7 1 9.3 17.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain BIR PF00653.21 CBY08203.1 - 4.6e-34 116.9 0.2 3.6e-16 59.6 0.1 2.1 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 CBY08203.1 - 5.2e-05 23.3 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 1 C3HC zinc finger-like PyrI_C PF02748.15 CBY08203.1 - 0.0037 17.1 0.7 3.7 7.5 0.0 2.6 3 0 0 3 3 3 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-ribbon_3 PF13248.6 CBY08203.1 - 0.55 9.7 0.2 0.55 9.7 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain WBP-1 PF11669.8 CBY08205.1 - 3.7e-06 27.5 0.0 6.3e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 WW domain-binding protein 1 Pox_EPC_I2-L1 PF12575.8 CBY08205.1 - 0.022 15.0 1.1 0.4 10.9 0.1 2.5 2 1 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 KfrA_N PF11740.8 CBY08206.1 - 0.0034 18.0 0.0 0.0051 17.5 0.0 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term RNA_POL_M_15KD PF02150.16 CBY08207.1 - 0.00014 21.6 2.0 0.00014 21.6 2.0 3.2 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CBY08207.1 - 0.00016 21.5 21.2 0.00027 20.7 11.7 3.1 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) HypA PF01155.19 CBY08207.1 - 0.01 15.9 1.9 0.01 15.9 1.9 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 CBY08207.1 - 0.018 15.0 5.2 0.018 15.0 5.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 CBY08207.1 - 0.043 14.2 4.0 0.043 14.2 4.0 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar CpXC PF14353.6 CBY08207.1 - 0.86 9.7 12.5 0.17 11.9 1.2 2.4 1 1 1 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.10 CBY08207.1 - 1.3 9.2 15.0 2.9 8.1 1.3 3.2 3 0 0 3 3 3 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 CBY08207.1 - 1.7 8.6 10.1 3.8 7.5 3.1 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.6 CBY08207.1 - 2.2 8.9 14.2 10 6.7 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-Mss51 PF13824.6 CBY08207.1 - 5.2 7.3 9.8 5.5 7.2 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3268 PF11672.8 CBY08207.1 - 9.5 6.6 10.3 4.2 7.7 3.3 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain CDC45 PF02724.14 CBY08208.1 - 3.2 5.9 17.8 4.4 5.5 17.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Myosin_head PF00063.21 CBY08210.1 - 1.4e-259 863.0 0.3 2.6e-259 862.1 0.3 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 CBY08210.1 - 1.1e-23 83.5 3.8 1.1e-23 83.5 3.8 2.8 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 CBY08210.1 - 1.1e-10 40.4 30.5 6.8e-05 22.3 0.8 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY08210.1 - 0.018 15.3 3.8 0.019 15.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Ribonucleas_3_2 PF11469.8 CBY08210.1 - 0.15 12.5 1.0 0.57 10.6 1.0 2.0 1 0 0 1 1 1 0 Ribonuclease III AAA_16 PF13191.6 CBY08210.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.5 3 1 1 4 4 4 0 AAA ATPase domain Erf4 PF10256.9 CBY08210.1 - 8.5 6.5 6.9 8.1 6.6 0.4 3.5 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family SYCE1 PF15233.6 CBY08211.1 - 0.0031 17.6 7.4 0.0031 17.6 7.4 2.3 1 1 1 2 2 2 1 Synaptonemal complex central element protein 1 Golgin_A5 PF09787.9 CBY08211.1 - 0.0033 17.0 8.4 0.0033 17.0 8.4 2.0 1 1 1 2 2 2 1 Golgin subfamily A member 5 CALCOCO1 PF07888.11 CBY08211.1 - 0.022 13.7 12.8 0.026 13.4 12.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like LXG PF04740.12 CBY08211.1 - 0.025 14.3 9.4 0.081 12.6 3.9 2.6 1 1 1 2 2 2 0 LXG domain of WXG superfamily ADIP PF11559.8 CBY08211.1 - 0.026 14.6 14.4 0.62 10.1 7.4 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 CBY08211.1 - 0.038 14.5 10.9 0.061 13.8 10.9 1.4 1 0 0 1 1 1 0 Fez1 PTPlike_phytase PF14566.6 CBY08211.1 - 0.051 13.7 6.7 0.044 13.9 5.1 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate RPW8 PF05659.11 CBY08211.1 - 0.06 13.0 6.0 0.38 10.4 1.1 3.1 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4407 PF14362.6 CBY08211.1 - 0.082 12.3 7.0 0.11 11.9 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 CBY08211.1 - 0.091 12.8 12.5 0.17 12.0 10.4 2.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 CBY08211.1 - 0.099 13.6 12.1 2.8 8.9 0.5 2.5 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain RNA_pol_Rpc4 PF05132.14 CBY08211.1 - 0.22 11.9 1.1 0.29 11.5 1.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 HIP1_clath_bdg PF16515.5 CBY08211.1 - 0.26 11.9 11.2 2.7 8.7 1.8 2.8 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF724 PF05266.14 CBY08211.1 - 0.28 11.0 13.3 0.11 12.4 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HrpB7 PF09486.10 CBY08211.1 - 0.28 11.5 6.5 1.6 9.1 1.3 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DASH_Duo1 PF08651.10 CBY08211.1 - 0.38 10.6 5.9 0.7 9.7 0.0 3.2 2 1 0 3 3 3 0 DASH complex subunit Duo1 Lebercilin PF15619.6 CBY08211.1 - 0.53 9.9 16.5 5 6.7 16.5 2.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 CBY08211.1 - 0.54 10.4 17.2 1.1 9.3 7.4 2.9 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 CBY08211.1 - 0.55 10.4 14.4 2.6 8.2 7.0 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 CBY08211.1 - 0.61 10.4 16.1 26 5.1 13.5 3.8 1 1 1 2 2 2 0 Tho complex subunit 7 CC2-LZ PF16516.5 CBY08211.1 - 0.85 10.0 14.0 1.6 9.2 10.1 2.8 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator APG6_N PF17675.1 CBY08211.1 - 1.1 9.8 12.0 1.1 9.7 10.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 CBY08211.1 - 1.2 9.9 5.7 6.1 7.5 0.1 3.5 2 1 1 3 3 3 0 SlyX DUF745 PF05335.13 CBY08211.1 - 2.1 8.0 8.5 9.3 5.9 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF5082 PF16888.5 CBY08211.1 - 2.2 8.6 16.0 13 6.1 10.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Mod_r PF07200.13 CBY08211.1 - 2.5 8.2 12.9 1.1 9.3 4.8 2.6 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.15 CBY08211.1 - 2.9 7.7 13.2 3.4 7.5 0.9 2.9 2 1 1 3 3 3 0 Septum formation initiator Fib_alpha PF08702.10 CBY08211.1 - 2.9 8.1 15.6 5.4 7.2 6.9 3.0 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF4665 PF15679.5 CBY08211.1 - 3.4 8.4 12.6 6.4 7.5 4.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) BST2 PF16716.5 CBY08211.1 - 3.4 8.3 15.5 47 4.7 7.9 3.2 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 DHR10 PF18595.1 CBY08211.1 - 3.4 7.7 16.5 5 7.2 1.1 3.1 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Spc24 PF08286.11 CBY08211.1 - 3.6 7.9 11.4 2.2 8.5 0.3 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF4164 PF13747.6 CBY08211.1 - 4.4 7.6 13.5 1.7 8.9 4.4 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.19 CBY08211.1 - 5.2 4.9 13.0 0.61 7.9 0.5 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CBY08211.1 - 6 6.0 9.8 8 5.6 7.8 1.8 1 1 1 2 2 2 0 TMPIT-like protein CUB PF00431.20 CBY08212.1 - 4.4e-08 33.4 0.3 7.5e-08 32.7 0.3 1.4 1 0 0 1 1 1 1 CUB domain CUB PF00431.20 CBY08213.1 - 8.9e-09 35.7 1.2 1.1e-08 35.4 0.8 1.3 1 1 0 1 1 1 1 CUB domain DUF5332 PF17266.2 CBY08219.1 - 0.088 12.5 1.6 0.23 11.2 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5332) OxoGdeHyase_C PF16870.5 CBY08220.1 - 0.043 13.5 0.3 0.3 10.8 0.3 2.0 1 1 1 2 2 2 0 2-oxoglutarate dehydrogenase C-terminal Amidohydro_2 PF04909.14 CBY08221.1 - 8.2e-58 196.5 0.3 9.1e-58 196.3 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase Fringe PF02434.16 CBY08222.1 - 5.5e-12 45.7 0.0 2e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CBY08222.1 - 0.0019 18.0 0.3 0.0046 16.8 0.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase CHGN PF05679.16 CBY08223.1 - 8.3e-59 199.8 3.5 9.2e-38 130.3 0.0 2.2 1 1 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY08223.1 - 5.5e-07 29.2 0.2 1.3e-06 28.0 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY08223.1 - 0.019 14.7 0.1 0.045 13.6 0.1 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 DHHC PF01529.20 CBY08224.1 - 5.2e-31 107.5 11.2 5.2e-31 107.5 11.2 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Cytochrome-c551 PF10643.9 CBY08224.1 - 0.00086 18.9 1.0 0.079 12.5 0.0 2.3 2 0 0 2 2 2 2 Photosystem P840 reaction-centre cytochrome c-551 MAP17 PF15807.5 CBY08224.1 - 0.14 12.4 0.2 0.14 12.4 0.2 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4748 PF15932.5 CBY08224.1 - 0.8 9.5 3.2 1.8 8.4 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) RNA_pol_3_Rpc31 PF11705.8 CBY08225.1 - 2.2e-11 44.5 11.8 3.1e-11 44.0 11.8 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 YnfE PF17452.2 CBY08225.1 - 0.19 12.1 4.6 1.9 8.9 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized YnfE-like LRR19-TM PF15176.6 CBY08225.1 - 1.2 9.1 4.3 2.5 8.1 2.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Ion_trans PF00520.31 CBY08227.1 - 2.3e-42 145.0 44.8 5.5e-23 81.5 13.6 2.1 2 0 0 2 2 2 2 Ion transport protein Thiolase_N PF00108.23 CBY08228.1 - 1.7e-20 73.5 0.1 1.9e-19 70.0 0.1 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY08228.1 - 2e-12 46.9 0.3 6.7e-12 45.1 0.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY08228.1 - 0.00014 21.5 1.3 0.0007 19.2 1.3 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CBY08228.1 - 0.0013 18.7 0.2 0.17 11.9 0.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 CBY08228.1 - 0.0013 18.5 0.2 0.16 11.8 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PCNA_C PF02747.15 CBY08230.1 - 2.9e-47 160.0 0.1 5.3e-47 159.2 0.1 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 CBY08230.1 - 1.1e-41 141.4 5.1 2.3e-41 140.5 5.1 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 CBY08230.1 - 0.039 13.4 0.1 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 Rad9 Cadherin PF00028.17 CBY08231.1 - 6.6e-54 180.3 0.0 1.6e-13 50.9 0.0 6.1 6 0 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.12 CBY08231.1 - 1.6e-07 31.1 0.3 0.18 11.6 0.0 4.2 5 0 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 CBY08231.1 - 2.9e-05 24.0 4.1 0.27 11.2 0.1 4.7 5 0 0 5 5 5 3 Cadherin-like RET_CLD1 PF17756.1 CBY08231.1 - 0.0013 19.0 0.0 1.7 8.9 0.0 2.8 3 0 0 3 3 3 2 RET Cadherin like domain 1 PTR2 PF00854.21 CBY08233.1 - 6.5e-88 295.2 18.3 1.1e-45 156.2 4.1 3.1 2 1 1 3 3 3 3 POT family DUF3425 PF11905.8 CBY08233.1 - 0.046 13.7 0.3 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) DnaJ PF00226.31 CBY08234.1 - 2.7e-05 24.2 0.1 0.0079 16.3 0.1 2.4 1 1 1 2 2 2 2 DnaJ domain Mto2_bdg PF12808.7 CBY08234.1 - 0.065 13.5 3.5 0.065 13.5 3.5 1.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region M PF02370.16 CBY08234.1 - 0.14 12.8 6.1 3.2 8.6 2.6 2.3 2 0 0 2 2 2 0 M protein repeat Cu-oxidase_3 PF07732.15 CBY08235.1 - 5.1e-36 123.3 2.7 6.1e-36 123.0 0.3 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CBY08235.1 - 2.2e-21 76.0 1.6 2.2e-21 76.0 1.6 3.2 2 2 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 CBY08235.1 - 0.08 13.1 0.4 1 9.5 0.1 2.7 2 1 0 2 2 2 0 Multicopper oxidase DNApol_Exo PF18136.1 CBY08237.1 - 2.1e-65 220.7 0.0 4.2e-65 219.7 0.0 1.5 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CBY08237.1 - 2.7e-25 89.2 0.0 4.6e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A PP1_bind PF15276.6 CBY08237.1 - 0.076 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 1 binding Ribosomal_S9 PF00380.19 CBY08238.1 - 2e-14 54.2 0.3 1e-05 26.0 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein S9/S16 Ccdc124 PF06244.12 CBY08239.1 - 5.9e-29 101.2 32.9 2e-25 89.8 32.9 2.6 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF3053 PF11254.8 CBY08239.1 - 5.5 6.5 12.1 2 7.9 8.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) YABBY PF04690.13 CBY08239.1 - 7 7.2 15.7 0.1 13.2 1.8 2.2 1 1 1 2 2 2 0 YABBY protein CTNNBL PF08216.11 CBY08240.1 - 2.2e-31 108.1 1.5 3.8e-31 107.3 1.5 1.3 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear PDCD2_C PF04194.13 CBY08240.1 - 0.0015 18.7 3.5 0.0018 18.4 3.5 1.1 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Ribosomal_S9 PF00380.19 CBY08241.1 - 9.6e-15 55.2 0.3 6.1e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein S9/S16 Ccdc124 PF06244.12 CBY08242.1 - 3e-33 115.1 8.3 3e-33 115.1 8.3 2.6 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF3053 PF11254.8 CBY08242.1 - 7.1 6.1 13.0 2.3 7.8 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) YABBY PF04690.13 CBY08242.1 - 9 6.8 15.5 5.2e+02 1.1 15.5 2.2 1 1 0 1 1 1 0 YABBY protein CTNNBL PF08216.11 CBY08243.1 - 2.2e-29 101.7 1.2 2.2e-29 101.7 1.2 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear RIH_assoc PF08454.11 CBY08243.1 - 0.0006 19.6 0.8 0.39 10.6 0.0 3.8 3 1 1 4 4 4 2 RyR and IP3R Homology associated PDCD2_C PF04194.13 CBY08243.1 - 0.0076 16.3 3.6 0.021 14.9 3.6 1.7 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain FKBP_C PF00254.28 CBY08244.1 - 1.4e-33 115.1 0.0 1.7e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Baculo_PEP_C PF04513.12 CBY08245.1 - 0.00038 20.5 6.8 0.65 10.0 6.6 2.6 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus TBCC_N PF16752.5 CBY08245.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.8 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Fez1 PF06818.15 CBY08245.1 - 0.14 12.6 16.8 0.38 11.2 16.1 1.9 1 1 0 1 1 1 0 Fez1 DUF948 PF06103.11 CBY08245.1 - 0.23 11.7 11.2 0.69 10.2 4.5 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Hemagglutinin PF00509.18 CBY08245.1 - 0.26 9.6 2.4 0.35 9.2 2.4 1.2 1 0 0 1 1 1 0 Haemagglutinin YjcZ PF13990.6 CBY08245.1 - 0.41 10.0 5.3 0.69 9.2 4.8 1.5 1 1 0 1 1 1 0 YjcZ-like protein DUF1664 PF07889.12 CBY08245.1 - 0.59 10.2 15.1 0.11 12.6 3.1 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DegQ PF08181.11 CBY08245.1 - 0.74 10.0 0.1 0.74 10.0 0.1 3.2 4 0 0 4 4 4 0 DegQ (SacQ) family Allexi_40kDa PF05549.11 CBY08245.1 - 2.5 7.5 7.2 1.5 8.2 5.2 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein TolA_bind_tri PF16331.5 CBY08245.1 - 3.2 7.9 17.5 1.2 9.2 3.6 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation Jnk-SapK_ap_N PF09744.9 CBY08245.1 - 3.3 7.9 19.8 2.3 8.4 7.4 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 zf-C2H2 PF00096.26 CBY08246.1 - 4.6e-18 64.6 39.3 0.00018 21.8 2.8 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY08246.1 - 6.4e-16 57.7 35.5 0.0014 19.3 1.2 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY08246.1 - 7.7e-10 38.5 25.8 0.15 12.1 0.2 6.5 5 1 1 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY08246.1 - 3.4e-08 33.6 34.0 0.024 14.9 2.2 6.6 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY08246.1 - 4.5e-07 30.1 22.3 0.0013 19.0 0.5 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBY08246.1 - 1.1e-05 25.6 30.9 0.015 15.7 0.7 6.4 7 0 0 7 7 6 3 Zinc-finger double domain zf-C2HC_2 PF13913.6 CBY08246.1 - 0.0088 15.9 0.5 0.0088 15.9 0.5 5.7 6 1 0 6 6 6 2 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 CBY08246.1 - 0.017 14.9 1.4 0.017 14.9 1.4 4.4 5 0 0 5 5 5 0 zinc-finger C2H2-type zf_UBZ PF18439.1 CBY08246.1 - 0.17 11.5 12.6 1.1 8.9 0.5 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 CBY08246.1 - 0.97 9.5 16.7 1.7 8.7 0.0 4.5 3 1 0 3 3 3 0 BED zinc finger Baculo_IE-1 PF05290.11 CBY08246.1 - 1.4 8.8 8.8 1.3 9.0 0.6 3.0 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) LIM PF00412.22 CBY08246.1 - 1.5 9.1 21.3 0.83 9.9 3.1 4.1 2 1 2 4 4 4 0 LIM domain C1_2 PF03107.16 CBY08246.1 - 5.1 7.5 21.1 27 5.2 0.1 4.8 3 2 0 3 3 3 0 C1 domain Phage_30_3 PF08010.11 CBY08247.1 - 9.6 6.0 8.5 0.32 10.8 0.8 2.5 3 0 0 3 3 3 0 Bacteriophage protein GP30.3 Cu-oxidase_3 PF07732.15 CBY08248.1 - 1.4e-36 125.1 0.1 2.6e-36 124.2 0.1 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 CBY08248.1 - 4e-07 30.3 0.0 4.9e-06 26.7 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CBY08248.1 - 0.055 13.2 1.3 1.3 8.8 1.3 2.5 1 1 0 1 1 1 0 Multicopper oxidase CUB PF00431.20 CBY08249.1 - 7.7e-12 45.5 0.1 1.1e-11 45.0 0.1 1.2 1 0 0 1 1 1 1 CUB domain HLH PF00010.26 CBY08250.1 - 1.5e-10 40.9 5.5 1.5e-10 40.9 5.5 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain EGF_3 PF12947.7 CBY08251.1 - 1.6e-09 37.8 11.6 2.2e-06 27.8 0.2 8.5 7 1 1 9 9 9 5 EGF domain EGF PF00008.27 CBY08251.1 - 0.00044 20.5 61.9 0.14 12.5 2.4 9.5 8 3 1 9 9 9 5 EGF-like domain EGF_MSP1_1 PF12946.7 CBY08251.1 - 0.00053 20.0 6.5 0.00053 20.0 6.5 8.1 9 0 0 9 9 9 2 MSP1 EGF domain 1 PAS_9 PF13426.7 CBY08251.1 - 0.026 14.8 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 0 PAS domain GDP_Man_Dehyd PF16363.5 CBY08252.1 - 9.3e-47 160.0 0.0 1.2e-46 159.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY08252.1 - 2.1e-45 155.1 0.0 2.8e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBY08252.1 - 9.5e-15 54.3 0.0 1.8e-14 53.4 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CBY08252.1 - 7.9e-09 35.7 0.0 1.5e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CBY08252.1 - 1e-07 31.4 0.0 2.9e-07 29.9 0.0 1.8 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 CBY08252.1 - 2.6e-07 30.1 0.0 6.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CBY08252.1 - 1e-06 28.1 0.0 2.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CBY08252.1 - 0.09 12.2 0.3 0.41 10.1 0.3 2.1 1 1 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 CBY08252.1 - 0.19 12.0 0.0 3.6 7.9 0.0 2.3 1 1 0 1 1 1 0 TrkA-N domain RNA_polI_A14 PF08203.11 CBY08252.1 - 0.49 11.1 3.1 9.2 7.1 0.6 2.5 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Kelch_3 PF13415.6 CBY08253.1 - 0.01 16.1 0.0 0.38 11.1 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Lambda_Kil PF06301.11 CBY08253.1 - 0.042 13.5 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein Kelch_5 PF13854.6 CBY08253.1 - 0.12 12.4 0.6 5.7 7.0 0.1 2.7 2 0 0 2 2 2 0 Kelch motif Coatomer_b_Cpla PF14806.6 CBY08255.1 - 0.081 12.9 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Choline_kinase PF01633.20 CBY08256.1 - 1e-08 35.0 0.1 1.6e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY08256.1 - 3.3e-08 33.8 0.0 5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY08256.1 - 0.024 14.0 0.4 0.034 13.5 0.4 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_M14 PF00246.24 CBY08257.1 - 2.6e-63 214.5 0.1 3.5e-63 214.1 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY08257.1 - 0.016 15.6 0.0 0.042 14.3 0.0 1.8 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Pkinase PF00069.25 CBY08260.1 - 1.7e-31 109.6 0.0 2.8e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Zona_pellucida PF00100.23 CBY08260.1 - 2.9e-14 53.5 0.0 4.7e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Pkinase_Tyr PF07714.17 CBY08260.1 - 2.4e-08 33.6 0.0 3.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY08260.1 - 1.2e-05 24.8 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY08260.1 - 0.0012 18.5 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY08260.1 - 0.0071 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY08260.1 - 0.01 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CBY08260.1 - 0.026 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family SYCP2_SLD PF18584.1 CBY08262.1 - 0.0019 18.4 0.9 0.0046 17.2 0.4 1.8 2 0 0 2 2 2 1 Synaptonemal complex 2 Spt16M-like domain Surp PF01805.20 CBY08262.1 - 0.065 13.2 0.8 7.8 6.6 0.0 3.3 3 0 0 3 3 3 0 Surp module Zona_pellucida PF00100.23 CBY08263.1 - 1.7e-29 103.4 8.2 2.2e-29 103.0 8.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FlaC_arch PF05377.11 CBY08263.1 - 0.048 14.1 0.1 0.085 13.3 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1184 PF06683.11 CBY08264.1 - 0.054 13.0 0.1 0.067 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) Phasin PF05597.11 CBY08265.1 - 0.0093 16.0 3.0 0.0093 16.0 3.0 2.2 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Mu-like_Pro PF10123.9 CBY08265.1 - 0.029 13.9 0.8 0.033 13.7 0.8 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein HSCB_C PF07743.13 CBY08265.1 - 0.1 13.1 11.2 0.78 10.3 5.2 2.7 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Med4 PF10018.9 CBY08265.1 - 1.1 8.9 9.2 0.064 12.9 2.1 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Spc24 PF08286.11 CBY08265.1 - 1.4 9.2 11.7 2.5 8.4 0.8 3.2 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 CBY08265.1 - 1.4 9.3 8.1 2.5 8.6 0.9 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 CBY08265.1 - 6.1 7.1 10.2 11 6.3 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF2256 PF10013.9 CBY08266.1 - 0.09 12.9 0.9 0.14 12.3 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Nebulin PF00880.18 CBY08267.1 - 8.6e-18 63.9 74.3 2.5e-05 24.1 3.4 11.4 11 0 0 11 11 11 9 Nebulin repeat Sulfotransfer_1 PF00685.27 CBY08270.1 - 2.4e-19 69.9 0.2 5e-19 68.8 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY08270.1 - 5.4e-10 40.0 0.0 4.4e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family DUF3131 PF11329.8 CBY08270.1 - 0.052 12.6 0.0 0.41 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3131) zf-Di19 PF05605.12 CBY08271.1 - 1.2e-10 41.5 58.2 0.00037 20.7 0.6 11.1 12 0 0 12 12 12 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CBY08271.1 - 2.9e-05 24.5 102.3 0.035 14.9 0.2 17.7 18 0 0 18 18 18 6 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY08271.1 - 0.00064 20.0 82.9 0.021 15.3 0.1 14.8 16 0 0 16 16 16 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CBY08271.1 - 0.14 12.0 0.0 0.14 12.0 0.0 8.0 9 0 0 9 9 9 0 C2H2-type zinc-finger domain zinc_ribbon_13 PF09855.9 CBY08271.1 - 0.75 10.0 6.5 15 5.9 0.3 3.9 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DNA_RNApol_7kD PF03604.13 CBY08271.1 - 0.86 9.3 9.3 1.2 8.9 0.1 4.5 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit ADH_N PF08240.12 CBY08272.1 - 1.9e-20 72.8 0.0 4e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBY08272.1 - 3.6e-18 65.8 0.1 9.5e-18 64.4 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBY08272.1 - 3.1e-07 30.1 0.3 1.2e-06 28.1 0.3 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CBY08272.1 - 0.016 14.5 0.2 0.026 13.8 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain T-box PF00907.22 CBY08273.1 - 1.8e-80 269.5 0.6 2.5e-80 269.1 0.0 1.5 2 0 0 2 2 2 1 T-box Macoilin PF09726.9 CBY08273.1 - 3.7 6.0 11.3 5 5.5 11.3 1.1 1 0 0 1 1 1 0 Macoilin family PsbN PF02468.15 CBY08275.1 - 0.83 9.5 2.8 0.93 9.4 2.8 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) TAF PF02969.17 CBY08276.1 - 0.032 14.4 0.1 0.056 13.6 0.1 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Steroid_dh PF02544.16 CBY08276.1 - 0.045 13.7 0.2 0.05 13.6 0.2 1.1 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Trypsin PF00089.26 CBY08278.1 - 1.3e-15 57.9 1.3 1.4e-15 57.7 1.3 1.1 1 0 0 1 1 1 1 Trypsin LRR_6 PF13516.6 CBY08278.1 - 0.12 12.4 0.0 0.46 10.7 0.0 2.1 1 0 0 1 1 1 0 Leucine Rich repeat Trypsin PF00089.26 CBY08280.1 - 7.3e-59 199.2 13.3 5.3e-43 147.4 1.0 2.7 2 1 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CBY08280.1 - 0.0082 17.0 0.0 0.068 14.1 0.0 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain ASD2 PF08687.11 CBY08280.1 - 0.53 9.8 5.3 1.1 8.7 5.3 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Mucin PF01456.17 CBY08280.1 - 1.1 9.3 24.6 2.3 8.2 24.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Auto_anti-p27 PF06677.12 CBY08281.1 - 0.024 14.8 1.5 0.14 12.3 2.0 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GGN PF15685.5 CBY08281.1 - 0.38 9.8 0.2 0.4 9.7 0.2 1.0 1 0 0 1 1 1 0 Gametogenetin LIM PF00412.22 CBY08282.1 - 5.4e-32 109.8 62.6 7.5e-09 35.7 8.2 4.6 5 0 0 5 5 5 4 LIM domain Sulfotransfer_1 PF00685.27 CBY08283.1 - 1.3e-16 60.9 1.6 3e-16 59.7 1.6 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY08283.1 - 1.1e-09 39.0 0.1 9.1e-09 36.0 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase family Notch PF00066.17 CBY08283.1 - 0.15 12.6 1.6 0.47 11.0 1.6 1.9 1 0 0 1 1 1 0 LNR domain DUF4912 PF16258.5 CBY08283.1 - 0.2 11.9 3.6 0.52 10.6 1.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4912) zf-RING_2 PF13639.6 CBY08284.1 - 3.8e-09 36.7 5.9 3.8e-09 36.7 5.9 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY08284.1 - 1.6e-08 34.3 5.2 1.6e-08 34.3 5.2 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY08284.1 - 3.6e-07 30.0 7.5 3.6e-07 30.0 7.5 3.4 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY08284.1 - 1.1e-06 28.5 3.3 1.1e-06 28.5 3.3 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY08284.1 - 7.6e-06 25.7 6.9 7.6e-06 25.7 6.9 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY08284.1 - 9.7e-06 25.8 4.7 9.7e-06 25.8 4.7 3.3 2 2 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY08284.1 - 1.8e-05 24.5 4.8 1.8e-05 24.5 4.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY08284.1 - 0.0013 18.8 3.0 0.0013 18.8 3.0 2.9 4 1 0 4 4 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBY08284.1 - 0.0037 17.1 4.9 0.0037 17.1 4.9 3.2 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY08284.1 - 0.011 15.5 13.0 0.14 12.0 5.0 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Fungal_TACC PF12709.7 CBY08284.1 - 0.036 14.5 4.5 0.036 14.5 4.5 3.6 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins GyrI-like PF06445.15 CBY08284.1 - 0.07 13.4 0.3 0.12 12.7 0.3 1.3 1 0 0 1 1 1 0 GyrI-like small molecule binding domain zf_CopZ PF18423.1 CBY08284.1 - 0.22 11.5 6.4 2.1 8.4 0.0 3.6 3 0 0 3 3 3 0 Zinc binding domain MRP-L47 PF06984.13 CBY08284.1 - 0.26 11.4 7.7 0.27 11.4 1.3 3.0 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) zf-ANAPC11 PF12861.7 CBY08284.1 - 8.7 6.5 10.6 0.63 10.1 1.5 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_A14 PF05767.12 CBY08285.1 - 0.052 13.7 0.3 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Na_sulph_symp PF00939.19 CBY08286.1 - 3e-87 293.6 17.7 4e-87 293.2 17.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY08286.1 - 1.3e-29 103.4 39.1 3.6e-17 62.5 2.8 3.1 2 1 1 3 3 3 3 Citrate transporter 7TM_GPCR_Srz PF10325.9 CBY08286.1 - 0.28 10.5 9.7 0.014 14.8 1.4 2.9 3 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srz zf-C2H2 PF00096.26 CBY08289.1 - 0.012 16.0 2.8 0.022 15.2 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type PBP_sp32 PF07222.12 CBY08289.1 - 2.3 7.6 8.3 4.6 6.6 8.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Cyclin_N2 PF16500.5 CBY08289.1 - 3.3 8.4 9.9 5.9 7.6 8.0 2.3 1 1 1 2 2 2 0 N-terminal region of cyclin_N Cation_efflux PF01545.21 CBY08291.1 - 6.2e-47 159.9 7.5 7.5e-47 159.6 7.5 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5134 PF17197.4 CBY08291.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) PDZ_6 PF17820.1 CBY08292.1 - 3.7e-22 77.9 2.9 1.7e-10 40.6 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 CBY08292.1 - 1.8e-20 73.0 7.0 2.4e-08 34.2 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CBY08292.1 - 1.7e-09 37.9 2.3 0.0016 18.8 0.0 3.2 3 0 0 3 3 3 2 PDZ domain Connexin PF00029.19 CBY08294.1 - 8.7e-10 38.7 0.0 9.7e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Connexin Zona_pellucida PF00100.23 CBY08296.1 - 6.7e-42 144.1 5.8 7.8e-42 143.8 5.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain WSC PF01822.19 CBY08297.1 - 0.44 10.8 9.5 4.6 7.5 0.3 2.3 2 0 0 2 2 2 0 WSC domain PT-VENN PF04829.13 CBY08300.1 - 0.052 13.6 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Pkinase_Tyr PF07714.17 CBY08300.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Kelch_3 PF13415.6 CBY08301.1 - 1.3e-36 124.2 0.3 7.3e-07 29.3 0.0 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY08301.1 - 7.7e-34 115.5 3.4 1.8e-07 31.0 0.0 6.6 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY08301.1 - 4.3e-24 83.5 6.7 0.00018 21.4 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CBY08301.1 - 9.9e-24 82.8 8.4 0.0003 20.9 0.1 6.2 4 2 2 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CBY08301.1 - 3.6e-19 68.3 1.2 0.011 15.7 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CBY08301.1 - 8e-16 57.4 8.6 3.6e-05 23.3 0.0 6.9 6 2 0 6 6 6 4 Kelch motif DUF4110 PF13422.6 CBY08301.1 - 8e-05 22.6 0.7 8e-05 22.6 0.7 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) CBFD_NFYB_HMF PF00808.23 CBY08302.1 - 6.9e-19 67.9 0.5 1.1e-18 67.2 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY08302.1 - 4.5e-05 23.8 1.2 8e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 CBY08302.1 - 9.1e-05 22.6 0.2 0.00019 21.6 0.2 1.5 1 0 0 1 1 1 1 CENP-W protein Pox_MCEL PF03291.16 CBY08303.1 - 3.3e-75 253.3 0.8 3.8e-75 253.1 0.8 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CBY08303.1 - 5.6e-11 43.0 0.0 1.3e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY08303.1 - 2.8e-09 37.0 0.0 4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY08303.1 - 1.3e-08 35.3 0.0 2.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY08303.1 - 2.8e-05 24.8 0.0 5.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY08303.1 - 0.001 18.9 0.1 0.002 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY08303.1 - 0.014 14.9 0.0 0.039 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 CBY08303.1 - 0.04 13.1 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Cons_hypoth95 PF03602.15 CBY08303.1 - 0.071 12.8 0.1 0.17 11.5 0.1 1.7 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Josephin PF02099.17 CBY08304.1 - 4.6e-26 91.9 0.3 3.4e-24 85.8 0.3 2.0 1 1 0 1 1 1 1 Josephin Cadherin PF00028.17 CBY08307.1 - 1.1e-27 96.3 0.7 8.3e-10 39.0 0.1 3.7 3 0 0 3 3 3 3 Cadherin domain Cadherin_C PF01049.17 CBY08307.1 - 1.5e-11 44.8 0.4 9.1e-11 42.3 0.4 2.2 1 1 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 CBY08307.1 - 0.098 12.5 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Cadherin-like DUF2748 PF10871.8 CBY08309.1 - 0.0085 14.8 0.7 0.0085 14.8 0.7 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2748) Folliculin PF11704.8 CBY08309.1 - 0.9 9.4 7.5 0.11 12.4 1.0 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Pkinase_Tyr PF07714.17 CBY08310.1 - 1.3e-108 362.2 0.0 2.5e-74 249.9 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBY08310.1 - 3.4e-63 213.5 0.0 9.1e-43 146.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Gelsolin PF00626.22 CBY08311.1 - 5.4e-51 170.4 0.3 2.8e-12 46.3 0.0 6.5 7 0 0 7 7 7 5 Gelsolin repeat LRR_8 PF13855.6 CBY08311.1 - 1.1e-41 140.4 35.7 7.4e-12 44.9 3.0 6.7 6 0 0 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 CBY08311.1 - 2.8e-32 110.2 49.0 4.5e-08 33.2 2.2 8.0 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY08311.1 - 9.4e-10 37.7 37.1 3.2 8.6 1.6 12.0 12 1 0 12 12 12 4 Leucine Rich Repeat LRR_6 PF13516.6 CBY08311.1 - 0.00091 19.1 34.8 1.5 9.1 0.1 9.7 10 0 0 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.6 CBY08311.1 - 0.016 14.7 22.0 0.12 11.9 2.3 4.5 1 1 2 4 4 4 0 Leucine-rich repeat LRR_5 PF13306.6 CBY08311.1 - 0.033 14.1 5.2 0.13 12.2 1.0 3.3 3 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) ETF_alpha PF00766.19 CBY08312.1 - 8.6e-34 115.4 3.2 2.3e-33 114.1 0.5 2.5 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 CBY08312.1 - 3.5e-33 115.0 8.5 3.5e-33 115.0 8.5 1.5 2 0 0 2 2 2 1 Electron transfer flavoprotein domain CSD PF00313.22 CBY08313.1 - 2.9e-25 87.9 1.6 2.9e-25 87.9 1.6 1.6 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CBY08313.1 - 0.0018 17.9 0.0 0.0083 15.8 0.0 2.2 1 0 0 1 1 1 1 Ribonuclease B OB domain SRP-alpha_N PF04086.13 CBY08313.1 - 5.7 6.8 13.8 7.7 6.3 13.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FAM92 PF06730.11 CBY08314.1 - 7.9e-28 97.4 7.3 1.2e-27 96.9 7.3 1.2 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.10 CBY08314.1 - 0.0019 17.8 11.6 0.13 11.8 10.8 3.0 2 1 1 3 3 3 2 Vps5 C terminal like LMBR1 PF04791.16 CBY08314.1 - 0.71 8.7 7.0 0.79 8.6 7.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S8 PF00082.22 CBY08316.1 - 1.7e-47 162.1 3.3 2.2e-47 161.8 3.3 1.1 1 0 0 1 1 1 1 Subtilase family S8_pro-domain PF16470.5 CBY08316.1 - 2.9e-17 63.2 1.9 1.7e-16 60.8 2.5 2.0 2 0 0 2 2 2 1 Peptidase S8 pro-domain P_proprotein PF01483.20 CBY08316.1 - 3.9e-16 58.8 0.0 8.3e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Pkinase PF00069.25 CBY08317.1 - 1.7e-53 181.7 0.0 2.1e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08317.1 - 2.8e-42 144.8 0.0 3.4e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY08317.1 - 3.7e-08 33.0 0.0 7.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY08317.1 - 2.5e-05 23.4 0.2 3.4e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBY08317.1 - 0.004 16.8 1.1 0.0056 16.3 1.1 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY08317.1 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY08317.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBY08317.1 - 0.053 12.9 0.1 0.11 11.8 0.1 1.5 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.6 CBY08320.1 - 9.9e-10 38.6 7.2 2.2e-06 27.9 0.1 3.9 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY08320.1 - 7.3e-09 35.1 17.3 0.0058 16.6 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY08320.1 - 1.4e-07 32.0 0.3 0.00011 22.8 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY08320.1 - 3.7e-07 29.8 17.2 6.5e-05 22.8 0.1 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY08320.1 - 0.00011 21.8 15.6 0.00078 19.2 0.2 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY08320.1 - 0.00019 21.2 1.6 1.4 9.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY08320.1 - 0.00042 20.9 4.6 1.7 9.6 0.1 5.0 5 1 1 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY08320.1 - 0.00064 19.9 7.2 0.39 11.0 0.2 5.1 3 3 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 EzrA PF06160.12 CBY08320.1 - 0.0042 15.3 0.6 0.3 9.2 0.1 2.3 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA TPR_19 PF14559.6 CBY08320.1 - 0.0047 17.4 5.1 0.051 14.1 0.1 3.8 4 1 1 5 5 4 1 Tetratricopeptide repeat Qua1 PF16274.5 CBY08320.1 - 0.0058 16.4 0.6 0.87 9.5 0.1 3.2 3 0 0 3 3 3 1 Qua1 domain Clathrin_H_link PF13838.6 CBY08320.1 - 0.014 15.2 2.7 1.8 8.5 0.1 3.4 3 0 0 3 3 3 0 Clathrin-H-link Alkyl_sulf_dimr PF14863.6 CBY08320.1 - 0.024 15.1 6.9 5.6 7.4 0.1 3.5 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation ChaB PF06150.12 CBY08320.1 - 0.033 14.8 1.3 3.5 8.3 0.0 3.4 3 0 0 3 3 3 0 ChaB TPR_10 PF13374.6 CBY08320.1 - 0.034 14.0 10.9 4.5 7.3 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY08320.1 - 0.035 14.7 5.6 32 5.4 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Hypoth_Ymh PF09509.10 CBY08320.1 - 0.15 11.9 1.1 2.1 8.3 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) FumaraseC_C PF10415.9 CBY08320.1 - 0.46 10.9 7.3 8.9 6.8 0.1 3.6 3 0 0 3 3 3 0 Fumarase C C-terminus Fis1_TPR_C PF14853.6 CBY08320.1 - 0.87 9.7 3.8 21 5.3 0.1 3.6 5 0 0 5 5 3 0 Fis1 C-terminal tetratricopeptide repeat Pkinase PF00069.25 CBY08321.1 - 1.8e-58 198.0 0.2 3.1e-58 197.2 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08321.1 - 3.4e-37 128.1 0.1 7.8e-37 127.0 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CBY08321.1 - 6.6e-33 112.7 0.5 7.9e-19 67.6 0.2 2.7 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 CBY08321.1 - 7.1e-06 25.0 0.0 1.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY08321.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like CoA_binding PF02629.19 CBY08322.1 - 2.9e-25 88.8 2.4 4.4e-25 88.2 0.6 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CBY08322.1 - 1.6e-22 79.9 0.2 2.4e-22 79.4 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CBY08322.1 - 8.8e-08 32.0 0.0 1.8e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBY08322.1 - 0.018 15.5 0.0 0.063 13.8 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain Phospholip_A2_1 PF00068.19 CBY08323.1 - 5.2e-16 59.1 2.6 9.4e-16 58.3 2.6 1.4 1 0 0 1 1 1 1 Phospholipase A2 Strep_his_triad PF04270.13 CBY08323.1 - 0.067 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Streptococcal histidine triad protein Guanylate_kin PF00625.21 CBY08324.1 - 6.5e-30 104.2 0.4 5.1e-28 98.0 0.4 2.4 1 1 0 1 1 1 1 Guanylate kinase ImpA_N PF06812.12 CBY08324.1 - 0.00054 20.1 0.6 0.12 12.4 0.1 2.4 2 0 0 2 2 2 2 ImpA, N-terminal, type VI secretion system SH3_1 PF00018.28 CBY08324.1 - 0.0049 16.4 0.1 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF4757 PF15949.5 CBY08324.1 - 0.072 13.6 1.8 0.31 11.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) Asp PF00026.23 CBY08325.1 - 0.02 14.3 0.2 0.03 13.7 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Fibrinogen_C PF00147.18 CBY08327.1 - 2.6e-18 66.6 4.2 6.5e-18 65.3 4.2 1.6 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain HR1 PF02185.16 CBY08328.1 - 0.039 14.1 0.2 0.092 12.9 0.2 1.6 1 0 0 1 1 1 0 Hr1 repeat Lectin_C PF00059.21 CBY08329.1 - 2.8e-10 40.9 3.1 0.00039 21.1 0.0 2.2 2 0 0 2 2 2 2 Lectin C-type domain Zona_pellucida PF00100.23 CBY08330.1 - 5.4e-42 144.4 1.4 1.1e-41 143.3 1.4 1.6 1 0 0 1 1 1 1 Zona pellucida-like domain G8 PF10162.9 CBY08330.1 - 1.7e-41 141.2 0.0 3.9e-32 110.9 0.0 2.7 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 CBY08330.1 - 4.6e-39 132.4 17.8 1.2e-10 41.3 3.2 6.0 5 0 0 5 5 5 5 IPT/TIG domain Mucin2_WxxW PF13330.6 CBY08330.1 - 2.1e-09 38.1 3.8 2.1e-09 38.1 3.8 2.9 3 0 0 3 3 3 1 Mucin-2 protein WxxW repeating region Beta_helix PF13229.6 CBY08330.1 - 6.4e-07 29.3 37.3 0.001 19.0 11.9 6.2 4 3 1 5 5 5 3 Right handed beta helix region NosD PF05048.13 CBY08330.1 - 2.4e-06 27.0 8.1 0.00052 19.4 4.2 3.2 2 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) PAN_4 PF14295.6 CBY08331.1 - 0.00022 21.0 0.6 0.00022 21.0 0.6 2.4 2 0 0 2 2 2 1 PAN domain DUF3099 PF11298.8 CBY08333.1 - 0.16 12.1 0.5 0.21 11.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) BIR PF00653.21 CBY08334.1 - 2.3e-08 34.6 2.0 6.7e-08 33.1 0.1 2.7 3 0 0 3 3 3 1 Inhibitor of Apoptosis domain Guanylate_cyc PF00211.20 CBY08335.1 - 5.2e-38 130.5 0.0 1.2e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CBY08335.1 - 1.7e-18 66.8 0.1 1.3e-16 60.7 0.1 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CBY08335.1 - 6.7e-12 45.3 0.0 2.4e-09 37.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CBY08335.1 - 0.00012 21.6 0.7 0.00027 20.5 0.7 1.6 1 0 0 1 1 1 1 Heme NO binding associated TSP_1 PF00090.19 CBY08336.1 - 1e-19 70.4 61.3 1.3e-07 31.7 13.1 4.4 4 0 0 4 4 4 4 Thrombospondin type 1 domain Phage_connect_1 PF05135.13 CBY08336.1 - 0.0088 16.5 0.7 0.016 15.7 0.7 1.4 1 0 0 1 1 1 1 Phage gp6-like head-tail connector protein EGF_MSP1_1 PF12946.7 CBY08337.1 - 0.039 14.0 3.8 0.13 12.4 3.8 1.9 1 1 0 1 1 1 0 MSP1 EGF domain 1 EGF_3 PF12947.7 CBY08337.1 - 0.24 11.6 3.0 0.64 10.3 3.0 1.8 1 0 0 1 1 1 0 EGF domain DUF4934 PF16288.5 CBY08339.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) Homeodomain PF00046.29 CBY08340.1 - 0.0043 16.9 0.1 0.0083 15.9 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Trypsin PF00089.26 CBY08342.1 - 1.1e-27 97.4 0.0 1.3e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY08342.1 - 0.00033 21.6 0.0 0.00051 21.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Lectin_C PF00059.21 CBY08343.1 - 1.1e-18 68.0 2.9 1.1e-18 68.0 2.9 2.3 1 1 1 2 2 2 1 Lectin C-type domain WHEP-TRS PF00458.20 CBY08343.1 - 0.32 11.2 3.0 0.33 11.1 0.7 2.1 2 0 0 2 2 2 0 WHEP-TRS domain BAR_2 PF10455.9 CBY08344.1 - 0.012 14.7 6.4 0.015 14.4 6.4 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Mod_r PF07200.13 CBY08344.1 - 0.023 14.8 10.1 0.018 15.1 7.6 1.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Apolipoprotein PF01442.18 CBY08344.1 - 0.024 14.5 8.8 0.17 11.7 4.5 2.2 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain CMAS PF02353.20 CBY08344.1 - 0.055 12.8 0.3 0.098 11.9 0.3 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CytochromB561_N PF09786.9 CBY08344.1 - 0.097 11.7 1.7 0.11 11.5 1.7 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal OmpH PF03938.14 CBY08344.1 - 0.3 11.4 3.9 0.5 10.7 3.5 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1525 PF07511.11 CBY08344.1 - 0.38 10.9 2.8 19 5.5 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1525) Fib_alpha PF08702.10 CBY08344.1 - 0.41 10.8 10.4 0.21 11.8 4.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ACCA PF03255.14 CBY08344.1 - 0.69 9.8 8.0 0.24 11.3 1.8 2.6 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4795 PF16043.5 CBY08344.1 - 0.73 9.4 11.5 29 4.2 11.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PIN_8 PF18476.1 CBY08344.1 - 1.4 8.7 8.9 0.98 9.2 2.1 2.0 1 1 1 2 2 2 0 PIN like domain KxDL PF10241.9 CBY08344.1 - 1.7 9.0 8.0 0.46 10.8 1.8 2.6 1 1 0 2 2 2 0 Uncharacterized conserved protein DUF1690 PF07956.11 CBY08344.1 - 2.7 8.4 11.4 1.2 9.6 2.6 2.6 1 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Fcf2 PF08698.11 CBY08345.1 - 5.9e-31 106.7 2.3 5.9e-31 106.7 2.3 2.0 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing Ubie_methyltran PF01209.18 CBY08346.1 - 2.7e-86 288.7 0.3 4.3e-86 288.0 0.3 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CBY08346.1 - 1.8e-16 60.5 0.0 4.6e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY08346.1 - 4.2e-15 56.2 0.0 3.8e-14 53.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY08346.1 - 3.4e-11 43.2 0.0 3.2e-10 40.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY08346.1 - 1.2e-10 42.0 0.1 2.8e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY08346.1 - 2.4e-09 37.2 0.0 3.5e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CBY08346.1 - 5.8e-07 29.6 0.1 2.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase MetW PF07021.12 CBY08346.1 - 0.11 12.0 0.1 0.6 9.7 0.0 2.1 2 1 1 3 3 3 0 Methionine biosynthesis protein MetW Med3 PF11593.8 CBY08348.1 - 0.52 9.5 11.8 0.8 8.8 11.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SOG2 PF10428.9 CBY08348.1 - 2.9 7.0 17.0 3.6 6.7 17.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GDH_N PF12466.8 CBY08348.1 - 4.1 7.7 4.8 16 5.8 0.0 3.0 2 1 0 2 2 2 0 Glutamate dehydrogenase N terminal CCDC106 PF15794.5 CBY08349.1 - 0.87 9.3 3.7 1.3 8.7 3.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RGS_DHEX PF18148.1 CBY08350.1 - 8.8e-32 109.2 0.4 8.8e-32 109.2 0.4 2.2 2 0 0 2 2 2 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 CBY08350.1 - 1.9e-27 95.9 0.2 4e-26 91.6 0.2 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 CBY08350.1 - 1.1e-11 44.6 0.0 3.5e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 CBY08350.1 - 4.6e-05 23.3 0.1 0.00014 21.8 0.1 1.8 1 0 0 1 1 1 1 GGL domain DIT1_PvcA PF05141.12 CBY08350.1 - 0.33 10.4 4.6 0.84 9.0 4.6 1.6 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein RVT_1 PF00078.27 CBY08351.1 - 1.5e-13 50.8 0.1 4.2e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CBY08351.1 - 5.9e-13 48.7 0.0 2.4e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY08351.1 - 2e-09 37.6 0.0 1.2e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_C78 PF07910.13 CBY08351.1 - 8.5e-05 22.1 0.1 0.002 17.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase family C78 Integrase_H2C2 PF17921.1 CBY08351.1 - 0.00096 19.2 0.1 0.00096 19.2 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain DUF3634 PF12321.8 CBY08352.1 - 0.11 12.9 0.0 0.48 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3634) Gal-3-0_sulfotr PF06990.11 CBY08353.1 - 2.5e-85 286.8 3.7 1.4e-84 284.3 3.7 1.8 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY08353.1 - 1.3e-05 25.2 0.3 0.00011 22.3 0.3 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 CBY08353.1 - 0.0018 18.7 1.5 0.01 16.2 0.0 2.5 2 1 1 3 3 3 1 Sulfotransferase family RTP1_C1 PF10363.9 CBY08354.1 - 0.029 14.6 0.2 1.2 9.3 0.0 2.5 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 RICTOR_M PF14666.6 CBY08354.1 - 0.056 13.2 1.2 2 8.2 0.4 2.9 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain PAN_4 PF14295.6 CBY08357.1 - 0.0078 16.1 1.1 0.0078 16.1 1.1 1.9 2 0 0 2 2 2 1 PAN domain MFS_1 PF07690.16 CBY08358.1 - 4.6e-10 39.0 10.3 5.3e-10 38.7 10.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 CBY08358.1 - 0.049 12.0 1.9 0.056 11.8 1.9 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector TMEM208_SND2 PF05620.11 CBY08358.1 - 0.5 10.1 5.7 0.072 12.9 2.1 1.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Popeye PF04831.13 CBY08358.1 - 1.8 8.8 10.0 2.1 8.5 2.0 2.1 2 0 0 2 2 2 0 Popeye protein conserved region Ndc1_Nup PF09531.10 CBY08358.1 - 7.3 5.1 10.5 8.4 4.9 10.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CPP1-like PF11833.8 CBY08358.1 - 9.2 5.9 7.7 13 5.4 7.7 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like 3-HAO PF06052.12 CBY08359.1 - 1.7e-59 199.8 0.1 3.4e-59 198.8 0.1 1.5 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CBY08359.1 - 2.7e-07 30.2 0.0 0.00036 20.2 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Sugar_tr PF00083.24 CBY08360.1 - 2.9e-23 82.4 9.5 2.9e-23 82.4 9.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY08360.1 - 4.3e-22 78.5 23.7 5.8e-22 78.1 23.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CBY08360.1 - 0.00064 19.1 5.0 0.001 18.4 5.0 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF1232 PF06803.12 CBY08360.1 - 0.39 10.6 2.1 1.1 9.1 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) eIF_4EBP PF05456.11 CBY08361.1 - 1.4e-25 89.4 0.4 1.7e-25 89.2 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) ANAPC2 PF08672.11 CBY08362.1 - 6.6e-18 65.0 1.3 1.7e-17 63.7 0.4 2.4 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 CBY08362.1 - 2.4e-08 33.1 6.0 1.7e-07 30.3 5.2 2.4 1 1 1 2 2 2 1 Cullin family PCI PF01399.27 CBY08362.1 - 0.13 12.8 3.4 6 7.4 0.0 3.5 3 1 0 3 3 3 0 PCI domain Sugar_tr PF00083.24 CBY08365.1 - 5.6e-11 42.0 14.8 1e-10 41.1 14.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY08365.1 - 2.3e-09 36.7 11.8 6.8e-07 28.5 5.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_VLTF3 PF04947.14 CBY08365.1 - 0.077 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Deltaretro_Tax PF05599.11 CBY08365.1 - 0.1 13.1 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein PGG PF13962.6 CBY08365.1 - 2.8 7.8 9.6 1.1 9.1 0.9 2.7 2 1 0 2 2 2 0 Domain of unknown function zf-C3HC4_3 PF13920.6 CBY08366.1 - 5.8e-12 45.3 13.2 7.6e-12 44.9 13.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY08366.1 - 2.3e-06 27.3 11.9 3.1e-06 27.0 11.9 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY08366.1 - 7e-05 22.7 13.1 0.0001 22.2 13.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY08366.1 - 0.0011 19.2 15.3 0.0016 18.7 15.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RRN7 PF11781.8 CBY08366.1 - 0.28 10.9 0.1 0.28 10.9 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 BIR PF00653.21 CBY08367.1 - 1e-36 125.4 5.8 4.5e-18 65.7 0.9 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 CBY08367.1 - 9.1e-07 29.0 0.5 0.035 14.2 0.0 2.3 1 1 1 2 2 2 2 C3HC zinc finger-like FtsJ PF01728.19 CBY08368.1 - 3.4e-18 66.4 0.0 4.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CBY08368.1 - 0.0027 17.5 0.1 0.0047 16.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Neur_chan_LBD PF02931.23 CBY08370.1 - 4.7e-26 91.6 1.8 5.8e-26 91.3 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Sulfotransfer_1 PF00685.27 CBY08371.1 - 1.2e-16 61.0 0.0 2.7e-15 56.6 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY08371.1 - 2.5e-11 44.4 0.0 1.7e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family Kelch_6 PF13964.6 CBY08372.1 - 1.6e-12 47.2 0.0 5.4e-05 23.3 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 CBY08372.1 - 9.7e-08 31.5 0.1 0.011 15.3 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY08372.1 - 1.3e-07 31.4 1.1 8e-05 22.5 0.0 3.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CBY08372.1 - 3.5e-07 30.1 0.9 0.0064 16.5 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain TSP_1 PF00090.19 CBY08372.1 - 2.1e-06 27.8 9.4 2.1e-06 27.8 9.4 4.4 3 1 0 3 3 3 1 Thrombospondin type 1 domain Kelch_2 PF07646.15 CBY08372.1 - 4.3e-06 26.5 2.2 0.0045 16.9 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 CBY08372.1 - 6.4e-05 23.1 0.4 0.51 10.7 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain HLH PF00010.26 CBY08373.1 - 2e-13 50.1 0.8 3e-13 49.5 0.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A_type_inc PF04508.12 CBY08373.1 - 0.00047 19.9 2.1 0.04 13.8 0.1 2.7 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat DUF3573 PF12097.8 CBY08373.1 - 0.16 10.8 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) LapA_dom PF06305.11 CBY08374.1 - 0.24 11.2 0.6 0.65 9.8 0.6 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Cwf_Cwc_15 PF04889.12 CBY08375.1 - 0.3 10.8 14.2 0.37 10.5 14.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4407 PF14362.6 CBY08375.1 - 0.63 9.3 5.9 0.73 9.1 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5339 PF17274.2 CBY08375.1 - 1.8 9.5 11.7 0.54 11.1 3.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5339) TFIIE-A_C PF11521.8 CBY08375.1 - 2 8.7 16.9 0.095 13.0 5.0 2.2 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Uds1 PF15456.6 CBY08375.1 - 2.1 8.5 10.5 2.7 8.2 10.2 1.4 1 1 0 1 1 1 0 Up-regulated During Septation DUF4666 PF15697.5 CBY08375.1 - 2.6 8.7 5.5 0.28 11.9 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) LMBR1 PF04791.16 CBY08375.1 - 6 5.6 5.7 6.9 5.5 5.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0061 PF02696.14 CBY08377.1 - 0.35 9.6 2.2 0.4 9.4 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family UPF0560 PF10577.9 CBY08377.1 - 0.99 7.8 10.3 1.1 7.7 10.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Iwr1 PF08574.10 CBY08377.1 - 1.6 9.8 13.9 0.44 11.6 5.4 2.3 2 0 0 2 2 2 0 Transcription factor Iwr1 RR_TM4-6 PF06459.12 CBY08377.1 - 1.9 8.2 21.3 2.2 8.1 21.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 CBY08377.1 - 2.8 6.3 19.8 2.9 6.3 19.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 CBY08377.1 - 2.9 7.2 10.3 3.5 6.9 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 CBY08377.1 - 3.9 7.8 12.6 2.1 8.6 3.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 MFS_1 PF07690.16 CBY08378.1 - 5.6e-11 42.0 13.1 2.6e-09 36.5 3.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily PMT PF02366.18 CBY08380.1 - 0.52 9.8 6.8 0.67 9.5 6.8 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase HKR_ArcB_TM PF18415.1 CBY08380.1 - 5.9 7.8 7.2 12 6.7 0.2 2.6 2 1 1 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain Filament PF00038.21 CBY08381.1 - 7e-84 282.1 47.5 9e-84 281.7 47.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein GAS PF13851.6 CBY08381.1 - 8e-05 22.1 39.6 0.016 14.6 19.3 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 CBY08381.1 - 0.0003 20.9 1.4 0.0003 20.9 1.4 4.1 1 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus DHR10 PF18595.1 CBY08381.1 - 0.00059 19.9 8.5 0.00059 19.9 8.5 5.0 4 2 2 6 6 5 1 Designed helical repeat protein 10 domain Spc7 PF08317.11 CBY08381.1 - 0.00093 18.2 41.7 0.0056 15.6 12.4 3.1 1 1 3 4 4 4 3 Spc7 kinetochore protein Apolipoprotein PF01442.18 CBY08381.1 - 0.0012 18.8 42.5 0.095 12.6 1.7 3.2 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain TPR_MLP1_2 PF07926.12 CBY08381.1 - 0.0018 18.3 44.9 0.23 11.5 3.4 4.1 1 1 2 4 4 3 3 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CBY08381.1 - 0.0068 16.4 17.3 0.34 11.0 0.2 4.4 3 1 1 5 5 5 2 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.19 CBY08381.1 - 0.0069 14.3 41.3 0.068 11.0 40.5 1.9 1 1 0 1 1 1 1 Myosin tail YscO PF07321.12 CBY08381.1 - 0.0081 16.1 1.6 0.0081 16.1 1.6 4.5 2 2 2 4 4 4 1 Type III secretion protein YscO CENP-F_leu_zip PF10473.9 CBY08381.1 - 0.018 15.1 43.4 0.053 13.6 10.4 3.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spidroin_N PF16763.5 CBY08381.1 - 0.033 14.2 0.5 0.33 11.0 0.0 2.8 2 1 1 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term CwsA PF10814.8 CBY08381.1 - 0.045 13.9 0.2 0.14 12.4 0.2 1.8 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA PfkB PF00294.24 CBY08381.1 - 0.046 13.0 0.2 0.046 13.0 0.2 2.4 3 0 0 3 3 3 0 pfkB family carbohydrate kinase APG6_N PF17675.1 CBY08381.1 - 0.047 14.2 52.4 0.26 11.8 12.9 4.2 2 2 1 4 4 4 0 Apg6 coiled-coil region DUF5082 PF16888.5 CBY08381.1 - 0.071 13.4 0.5 0.071 13.4 0.5 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF5082) Laminin_I PF06008.14 CBY08381.1 - 0.096 12.4 34.0 0.0081 15.9 27.6 2.2 1 1 1 2 2 2 0 Laminin Domain I DUF3198 PF11433.8 CBY08381.1 - 0.11 12.4 2.0 0.26 11.2 0.5 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3198) ApoLp-III PF07464.11 CBY08381.1 - 0.11 12.5 18.4 0.028 14.5 4.5 4.1 1 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Prefoldin PF02996.17 CBY08381.1 - 0.12 12.2 28.1 0.065 13.1 2.4 5.1 3 2 1 4 4 4 0 Prefoldin subunit FPP PF05911.11 CBY08381.1 - 0.15 10.2 35.8 0.069 11.3 16.7 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF3584 PF12128.8 CBY08381.1 - 0.25 8.8 34.7 0.64 7.5 34.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 CBY08381.1 - 0.27 10.6 40.4 0.41 10.1 14.5 2.8 1 1 2 3 3 3 0 Golgin subfamily A member 5 Lebercilin PF15619.6 CBY08381.1 - 0.29 10.8 50.8 2.2 7.9 14.7 3.4 2 1 2 4 4 3 0 Ciliary protein causing Leber congenital amaurosis disease BLOC1_2 PF10046.9 CBY08381.1 - 0.4 11.0 28.1 0.031 14.6 4.8 4.4 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 CBY08381.1 - 0.52 9.6 27.1 0.048 13.0 11.6 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 CBY08381.1 - 0.85 9.4 17.1 4.1 7.1 2.7 4.5 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain OmpH PF03938.14 CBY08381.1 - 1.1 9.6 32.2 0.51 10.7 0.8 4.1 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) WXG100 PF06013.12 CBY08381.1 - 1.7 9.0 11.6 23 5.3 0.6 4.6 3 2 2 5 5 4 0 Proteins of 100 residues with WXG Phage_Mu_Gam PF07352.12 CBY08381.1 - 1.8 8.5 28.0 0.21 11.5 2.8 4.5 1 1 2 4 4 4 0 Bacteriophage Mu Gam like protein T3SS_needle_F PF09392.10 CBY08381.1 - 1.9 8.8 8.0 3.8 7.8 1.6 3.4 2 1 1 3 3 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF4472 PF14739.6 CBY08381.1 - 2 9.2 32.2 0.075 13.8 8.5 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4472) FUSC PF04632.12 CBY08381.1 - 2.5 6.5 19.4 0.73 8.3 3.9 2.3 1 1 0 2 2 2 0 Fusaric acid resistance protein family ATG16 PF08614.11 CBY08381.1 - 2.8 8.1 48.0 1 9.6 9.1 4.1 1 1 3 4 4 3 0 Autophagy protein 16 (ATG16) YtxH PF12732.7 CBY08381.1 - 2.8 8.5 10.7 4.9 7.8 1.3 4.4 3 2 0 3 3 3 0 YtxH-like protein Exonuc_VII_L PF02601.15 CBY08381.1 - 2.8 7.4 34.5 34 3.9 12.9 2.6 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF489 PF04356.12 CBY08381.1 - 3.8 7.5 15.3 5.8 6.9 4.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF16 PF01519.16 CBY08381.1 - 3.9 8.0 22.1 0.32 11.5 3.5 3.7 1 1 1 2 2 1 0 Protein of unknown function DUF16 Prominin PF05478.11 CBY08381.1 - 4.2 5.2 23.9 7.3 4.4 17.2 2.6 1 1 1 2 2 2 0 Prominin Fez1 PF06818.15 CBY08381.1 - 4.3 7.7 37.1 1 9.7 9.0 3.3 1 1 1 2 2 2 0 Fez1 FliJ PF02050.16 CBY08381.1 - 4.8 7.4 32.0 2 8.7 11.3 4.1 2 2 1 3 3 3 0 Flagellar FliJ protein FapA PF03961.13 CBY08381.1 - 6.5 5.2 27.5 1.4 7.5 5.6 3.4 1 1 3 4 4 4 0 Flagellar Assembly Protein A Tup_N PF08581.10 CBY08381.1 - 8.8 6.7 38.7 0.64 10.4 4.9 5.7 2 2 4 6 6 6 0 Tup N-terminal DUF3450 PF11932.8 CBY08381.1 - 9.1 5.5 33.7 0.06 12.6 9.7 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) KxDL PF10241.9 CBY08382.1 - 0.18 12.1 30.0 0.19 12.1 6.4 5.2 3 1 0 4 4 4 0 Uncharacterized conserved protein Gelsolin PF00626.22 CBY08383.1 - 1.3e-61 204.4 0.1 2.5e-15 56.1 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat Tubulin PF00091.25 CBY08384.1 - 9.9e-70 234.7 0.0 1.6e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY08384.1 - 1.3e-43 148.2 0.1 2.2e-43 147.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY08384.1 - 5.5e-06 26.7 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBY08384.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBY08384.1 - 0.017 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin like DUF4703 PF15775.5 CBY08385.1 - 0.14 12.0 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Peptidase_C14 PF00656.22 CBY08387.1 - 4.9e-24 85.6 0.0 7.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Complex1_LYR PF05347.15 CBY08388.1 - 1e-07 31.9 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBY08388.1 - 0.013 16.2 0.0 0.027 15.2 0.0 1.6 1 0 0 1 1 1 0 Complex1_LYR-like FYVE PF01363.21 CBY08389.1 - 2e-05 24.6 14.6 3.8e-05 23.7 14.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger RBD PF02196.15 CBY08389.1 - 0.0023 18.0 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 Raf-like Ras-binding domain PolC_DP2 PF03833.13 CBY08389.1 - 0.3 8.9 4.7 0.38 8.6 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 THOC7 PF05615.13 CBY08390.1 - 8.6e-27 94.0 5.2 8.6e-27 94.0 5.2 1.8 1 1 1 2 2 2 1 Tho complex subunit 7 APG6_N PF17675.1 CBY08390.1 - 0.0018 18.8 1.7 0.0018 18.8 1.7 2.1 1 1 1 2 2 2 1 Apg6 coiled-coil region Herpes_V23 PF01802.17 CBY08390.1 - 0.041 13.3 0.8 0.055 12.9 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein HlyD_3 PF13437.6 CBY08390.1 - 0.28 11.9 1.6 0.58 10.9 1.6 1.6 1 1 0 1 1 1 0 HlyD family secretion protein DUF948 PF06103.11 CBY08390.1 - 0.64 10.3 4.9 0.78 10.0 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 CBY08390.1 - 2.9 8.4 12.4 0.17 12.4 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2175 PF09943.9 CBY08390.1 - 4.9 7.5 6.8 0.94 9.8 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Uso1_p115_C PF04871.13 CBY08390.1 - 5.9 7.3 21.8 4.1 7.8 18.2 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Diphthami_syn_2 PF01902.17 CBY08391.1 - 9.6e-46 156.0 0.0 1.5e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CBY08391.1 - 1.1e-15 57.7 0.0 4.6e-09 36.3 0.0 3.0 3 0 0 3 3 3 2 Endoribonuclease L-PSP BAR PF03114.18 CBY08392.1 - 7.7e-29 101.0 5.9 9.4e-29 100.7 5.9 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 CBY08392.1 - 1.5e-06 27.5 4.5 1.7e-06 27.4 4.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 CBY08392.1 - 6e-05 22.9 2.6 8.3e-05 22.4 2.6 1.2 1 0 0 1 1 1 1 BAR domain of APPL family FliJ PF02050.16 CBY08392.1 - 0.52 10.6 12.5 0.38 11.0 3.9 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein Peptidase_M13 PF01431.21 CBY08392.1 - 0.68 9.5 2.7 0.84 9.2 0.9 1.7 1 1 1 2 2 2 0 Peptidase family M13 DUF4407 PF14362.6 CBY08392.1 - 2.3 7.5 7.4 2 7.7 5.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BRE1 PF08647.11 CBY08392.1 - 3.3 7.9 11.5 0.077 13.1 1.1 2.8 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Tubulin PF00091.25 CBY08394.1 - 1.6e-53 181.8 0.0 2.2e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY08394.1 - 5.1e-16 59.0 0.0 1.2e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CBY08394.1 - 0.0022 17.3 0.1 0.0043 16.3 0.1 1.6 1 1 0 1 1 1 1 Tubulin like Abhydrolase_6 PF12697.7 CBY08395.1 - 1.6e-10 42.0 0.0 1.8e-06 28.8 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBY08395.1 - 6.7e-07 29.2 0.0 0.0042 16.7 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBY08395.1 - 6.5e-06 25.6 0.0 0.022 14.0 0.0 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 CBY08395.1 - 0.05 13.3 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PDR_assoc PF08370.11 CBY08395.1 - 0.076 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Abhydrolase_5 PF12695.7 CBY08395.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 CBY08395.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region TIP49 PF06068.13 CBY08396.1 - 3.7e-158 526.3 3.0 4.7e-158 526.0 3.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CBY08396.1 - 1.4e-25 89.2 0.1 5.6e-25 87.3 0.2 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 CBY08396.1 - 1.6e-09 37.7 1.3 3.5e-05 23.6 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 CBY08396.1 - 5.6e-09 36.5 2.5 2e-05 25.0 0.1 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBY08396.1 - 1.8e-06 28.0 0.1 0.0054 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY08396.1 - 4e-06 27.3 0.2 1.8e-05 25.2 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 CBY08396.1 - 1.8e-05 24.2 0.6 3.6e-05 23.2 0.6 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 CBY08396.1 - 5.3e-05 23.0 0.2 0.038 13.7 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 CBY08396.1 - 0.00013 22.3 0.3 0.23 11.8 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CBY08396.1 - 0.00026 21.4 5.5 0.0043 17.4 3.6 2.9 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBY08396.1 - 0.00037 19.9 2.2 0.017 14.5 0.8 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CBY08396.1 - 0.0014 18.2 0.2 0.0042 16.7 0.2 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBY08396.1 - 0.0024 17.2 0.6 0.008 15.5 0.3 2.0 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.9 CBY08396.1 - 0.0036 16.6 0.0 0.0066 15.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) MS_channel PF00924.18 CBY08396.1 - 0.0059 16.2 0.2 0.23 11.0 0.1 2.4 2 0 0 2 2 2 1 Mechanosensitive ion channel ATPase PF06745.13 CBY08396.1 - 0.008 15.6 2.1 0.016 14.6 2.1 1.6 1 1 0 1 1 1 1 KaiC NACHT PF05729.12 CBY08396.1 - 0.0092 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 CBY08396.1 - 0.027 14.2 0.9 0.94 9.2 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBY08396.1 - 0.031 13.8 2.1 0.048 13.2 0.1 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_11 PF13086.6 CBY08396.1 - 0.052 13.3 0.3 0.098 12.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CBY08396.1 - 0.086 12.3 3.7 0.33 10.4 0.6 2.6 2 1 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 CBY08396.1 - 0.2 11.7 1.1 0.39 10.7 0.4 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 CBY08396.1 - 0.35 11.3 2.5 0.17 12.4 0.3 1.6 2 0 0 2 2 1 0 AAA domain ResIII PF04851.15 CBY08396.1 - 0.5 10.4 3.6 4.5 7.2 1.2 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SPG4 PF17325.2 CBY08397.1 - 0.38 11.8 4.8 1.2 10.2 4.8 1.8 1 1 0 1 1 1 0 Stationary phase protein 4 GalP_UDP_transf PF01087.22 CBY08398.1 - 2.1e-68 230.4 0.2 3.2e-68 229.8 0.2 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 CBY08398.1 - 1e-57 194.5 0.0 2.4e-57 193.3 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4931 PF16285.5 CBY08398.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) DUF4921 PF16268.5 CBY08398.1 - 0.026 13.3 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) PC-Esterase PF13839.6 CBY08399.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p LemA PF04011.12 CBY08401.1 - 0.051 13.4 0.3 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 LemA family TMF_TATA_bd PF12325.8 CBY08401.1 - 0.11 12.8 2.0 0.22 11.8 0.1 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 CBY08401.1 - 0.33 11.9 4.5 0.62 11.0 0.1 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Corona_S2 PF01601.16 CBY08402.1 - 0.11 10.9 0.6 0.14 10.7 0.6 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PID PF00640.23 CBY08403.1 - 2e-18 66.8 1.3 2.8e-18 66.3 0.1 1.9 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) TFIIA_gamma_N PF02268.16 CBY08404.1 - 1.5e-21 76.2 0.6 2e-21 75.7 0.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 CBY08404.1 - 3e-21 75.3 2.7 4.5e-21 74.7 2.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit UCR_14kD PF02271.16 CBY08405.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit GKAP PF03359.13 CBY08406.1 - 5.6e-11 42.6 24.7 3.1e-09 36.9 24.7 2.4 1 1 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein zf-C2H2_jaz PF12171.8 CBY08407.1 - 1.4e-09 38.0 5.2 2.4e-09 37.2 5.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY08407.1 - 6.1e-05 23.3 3.2 0.0001 22.6 3.2 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CBY08407.1 - 0.0023 18.3 3.9 0.0042 17.4 3.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.12 CBY08407.1 - 0.021 15.1 0.8 0.031 14.5 0.2 1.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Syntaxin-6_N PF09177.11 CBY08408.1 - 0.00023 21.6 12.6 0.0086 16.6 6.4 3.3 1 1 1 2 2 2 1 Syntaxin 6, N-terminal CC2-LZ PF16516.5 CBY08408.1 - 0.0074 16.6 8.8 0.28 11.6 0.2 3.2 2 2 0 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GAS PF13851.6 CBY08408.1 - 0.013 14.9 13.4 0.041 13.2 3.6 3.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 CBY08408.1 - 0.013 15.7 10.7 0.12 12.5 0.4 2.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 CBY08408.1 - 0.014 15.2 9.2 1.8 8.3 0.8 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 Lzipper-MIP1 PF14389.6 CBY08408.1 - 0.018 15.3 11.1 0.085 13.2 2.9 3.8 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 ATG16 PF08614.11 CBY08408.1 - 0.024 14.9 4.0 0.024 14.9 4.0 3.1 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Gp58 PF07902.11 CBY08408.1 - 0.034 12.5 5.9 0.054 11.8 5.8 1.5 1 1 0 1 1 1 0 gp58-like protein CALCOCO1 PF07888.11 CBY08408.1 - 0.068 12.0 20.2 2.7 6.8 20.3 2.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Bap31_Bap29_C PF18035.1 CBY08408.1 - 0.081 12.9 3.6 0.27 11.3 0.1 3.4 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain UPF0242 PF06785.11 CBY08408.1 - 0.18 11.9 15.9 0.025 14.7 9.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 CBY08408.1 - 0.28 9.1 4.2 0.36 8.7 4.2 1.2 1 0 0 1 1 1 0 Prominin WXG100 PF06013.12 CBY08408.1 - 0.33 11.2 3.8 13 6.1 0.0 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 CBY08408.1 - 0.35 10.9 12.9 0.17 11.9 0.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ERM PF00769.19 CBY08408.1 - 0.39 10.5 20.7 2.4 7.9 6.7 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HMMR_N PF15905.5 CBY08408.1 - 0.43 10.0 21.6 0.063 12.7 12.4 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal USP8_interact PF08941.10 CBY08408.1 - 0.43 10.4 3.0 6.4 6.5 0.2 2.7 1 1 1 2 2 2 0 USP8 interacting CPSF100_C PF13299.6 CBY08408.1 - 0.77 9.9 6.1 0.23 11.6 2.9 1.7 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF724 PF05266.14 CBY08408.1 - 1.6 8.5 13.7 3.4 7.5 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 CBY08408.1 - 1.9 8.9 18.0 0.32 11.4 13.2 1.8 1 1 1 2 2 2 0 Fez1 FlaC_arch PF05377.11 CBY08408.1 - 2 8.8 7.2 5.6 7.4 0.1 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) TRAF_BIRC3_bd PF16673.5 CBY08408.1 - 2.1 8.2 8.1 1.2 9.0 0.1 3.7 3 2 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF3450 PF11932.8 CBY08408.1 - 2.1 7.6 14.6 2.8 7.2 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FAM76 PF16046.5 CBY08408.1 - 2.2 7.5 11.6 0.56 9.5 5.9 2.0 1 1 1 2 2 2 0 FAM76 protein DUF4407 PF14362.6 CBY08408.1 - 2.5 7.4 16.4 0.67 9.3 6.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SYCE1 PF15233.6 CBY08408.1 - 2.9 8.0 15.4 0.16 12.0 6.6 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Macoilin PF09726.9 CBY08408.1 - 2.9 6.3 16.7 0.061 11.9 3.3 2.0 1 1 1 2 2 2 0 Macoilin family DUF4472 PF14739.6 CBY08408.1 - 4.2 8.1 17.9 3.5 8.4 5.9 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) YabA PF06156.13 CBY08408.1 - 7.3 7.3 11.3 27 5.5 6.4 3.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF2968 PF11180.8 CBY08408.1 - 7.7 6.1 13.8 1.9 8.1 2.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Csm1_N PF18504.1 CBY08408.1 - 9.2 6.7 15.7 3.9 7.9 0.1 4.6 2 1 2 5 5 5 0 Csm1 N-terminal domain Flagellin_N PF00669.20 CBY08409.1 - 0.021 14.9 2.2 0.021 14.9 2.2 4.7 3 1 1 4 4 4 0 Bacterial flagellin N-terminal helical region PI3K_P85_iSH2 PF16454.5 CBY08409.1 - 0.031 13.9 0.6 0.031 13.9 0.6 8.0 4 2 1 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HALZ PF02183.18 CBY08409.1 - 0.091 13.0 0.2 0.091 13.0 0.2 11.4 12 0 0 12 12 12 0 Homeobox associated leucine zipper SH3_1 PF00018.28 CBY08410.1 - 2.9e-47 158.0 5.2 1.1e-15 56.9 0.6 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 CBY08410.1 - 4.2e-38 129.0 3.1 6.1e-15 54.8 0.5 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 CBY08410.1 - 1.1e-26 92.3 0.4 2e-09 37.0 0.3 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 CBY08410.1 - 4.4e-13 49.1 0.1 1.2e-12 47.8 0.1 1.8 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 CBY08410.1 - 1.1e-09 38.4 6.8 1e-05 25.7 0.1 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_10 PF17902.1 CBY08410.1 - 7e-08 32.4 1.7 0.00024 21.1 0.1 3.3 3 0 0 3 3 3 2 SH3 domain SH2_2 PF14633.6 CBY08410.1 - 0.0012 18.3 0.2 0.029 13.8 0.2 2.3 1 1 0 1 1 1 1 SH2 domain SH3_16 PF18348.1 CBY08410.1 - 0.007 16.1 0.1 1.2 8.9 0.2 2.6 2 0 0 2 2 2 1 Bacterial dipeptidyl-peptidase Sh3 domain DUF3827 PF12877.7 CBY08410.1 - 0.045 12.1 0.1 0.076 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Fibrinogen_C PF00147.18 CBY08411.1 - 3.1e-25 89.3 0.1 3.4e-25 89.1 0.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain HPIP_like PF18524.1 CBY08411.1 - 0.063 13.1 0.6 0.12 12.2 0.6 1.4 1 0 0 1 1 1 0 High potential iron-sulfur protein like Glyco_transf_10 PF00852.19 CBY08412.1 - 4.4e-44 150.3 1.2 7.9e-44 149.5 1.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY08412.1 - 3.6e-14 53.1 0.0 1e-13 51.7 0.0 1.8 1 1 1 2 2 2 1 Fucosyltransferase, N-terminal Gal-3-0_sulfotr PF06990.11 CBY08413.1 - 1.1e-36 126.6 1.5 8.2e-21 74.3 0.4 2.1 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase NHL PF01436.21 CBY08414.1 - 0.0065 16.4 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 NHL repeat SdiA-regulated PF06977.11 CBY08414.1 - 0.064 12.5 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 SdiA-regulated LSM PF01423.22 CBY08415.1 - 4.1e-20 71.3 0.3 4.7e-20 71.1 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY08415.1 - 2.3e-05 24.4 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CBY08415.1 - 0.031 14.4 0.1 0.036 14.2 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain TPH PF13868.6 CBY08416.1 - 6e-13 48.0 128.5 6e-13 48.0 128.5 2.2 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain ASF1_hist_chap PF04729.13 CBY08417.1 - 4.5e-59 198.8 0.0 5.4e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RHH_3 PF12651.7 CBY08417.1 - 0.13 12.3 0.6 6.3 6.8 0.0 2.8 3 0 0 3 3 3 0 Ribbon-helix-helix domain CRAL_TRIO_2 PF13716.6 CBY08418.1 - 1.1e-15 58.0 0.4 2.3e-15 57.0 0.3 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain BNIP2 PF12496.8 CBY08418.1 - 1.2e-07 32.3 7.0 4.6e-07 30.3 6.9 1.9 1 1 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO PF00650.20 CBY08418.1 - 0.00016 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain RRM_1 PF00076.22 CBY08419.1 - 1.7e-23 82.2 0.0 2.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY08419.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CBY08419.1 - 0.0046 16.6 0.0 0.0056 16.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBY08419.1 - 0.055 13.3 0.0 2.4 7.9 0.0 2.0 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 CBY08419.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif Ras PF00071.22 CBY08421.1 - 6e-51 172.3 0.1 6.6e-51 172.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY08421.1 - 1e-34 119.4 0.1 1.3e-34 119.0 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY08421.1 - 8.1e-16 58.0 0.0 9.9e-16 57.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY08421.1 - 2.9e-07 30.1 0.1 3.2e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY08421.1 - 9.4e-07 28.9 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBY08421.1 - 0.0006 19.3 0.0 0.00067 19.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY08421.1 - 0.0031 17.1 0.1 0.033 13.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CBY08421.1 - 0.0047 16.7 0.1 0.0091 15.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 CBY08421.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CBY08421.1 - 0.014 15.8 0.0 0.02 15.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBY08421.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 CBY08421.1 - 0.019 14.7 0.1 0.043 13.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CBY08421.1 - 0.024 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 CBY08421.1 - 0.054 12.6 0.1 0.17 10.9 0.0 1.8 1 1 1 2 2 2 0 MCM P-loop domain Septin PF00735.18 CBY08421.1 - 0.071 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 CBY08421.1 - 0.078 13.5 0.2 0.085 13.4 0.2 1.4 1 1 0 1 1 1 0 ABC transporter DUF4265 PF14085.6 CBY08421.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4265) RsgA_GTPase PF03193.16 CBY08421.1 - 0.09 12.7 0.2 0.28 11.1 0.1 1.8 1 1 0 2 2 2 0 RsgA GTPase TniB PF05621.11 CBY08421.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 CBY08421.1 - 0.14 11.7 0.2 0.32 10.5 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-C3HC4_3 PF13920.6 CBY08422.1 - 9.4e-07 28.6 5.9 1.5e-06 28.0 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY08422.1 - 2.6e-06 27.3 9.0 3.9e-06 26.7 9.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY08422.1 - 1.2e-05 25.6 8.5 1.8e-05 24.9 8.5 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBY08422.1 - 1.8e-05 24.5 7.5 3.2e-05 23.7 7.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBY08422.1 - 3.1e-05 23.9 1.3 9.6e-05 22.3 1.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 CBY08422.1 - 0.00043 20.0 5.4 0.00077 19.2 5.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CBY08422.1 - 0.0054 16.6 3.8 0.0096 15.8 3.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 CBY08422.1 - 0.0055 16.5 7.8 0.012 15.5 7.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY08422.1 - 0.01 15.7 9.3 0.019 14.8 9.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY08422.1 - 0.05 13.4 4.4 0.12 12.1 4.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.6 CBY08422.1 - 0.29 11.3 3.4 0.52 10.5 3.4 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger Mito_fiss_reg PF05308.11 CBY08422.1 - 0.32 11.1 6.3 0.49 10.4 5.3 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator Rtf2 PF04641.12 CBY08422.1 - 0.34 10.2 7.2 0.1 12.0 3.9 1.8 1 1 2 3 3 3 0 Rtf2 RING-finger FYVE PF01363.21 CBY08422.1 - 0.61 10.3 7.3 5.5 7.2 7.3 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_4 PF13894.6 CBY08422.1 - 2.7 9.1 6.9 12 7.0 0.2 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger DUF2039 PF10217.9 CBY08422.1 - 6.4 7.2 7.5 3.5 8.0 4.3 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) Sugar_tr PF00083.24 CBY08424.1 - 1.4e-29 103.3 23.4 6.5e-29 101.1 23.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY08424.1 - 1.4e-27 96.6 32.9 1.6e-20 73.4 13.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY08424.1 - 0.00024 20.1 0.0 0.02 13.7 0.0 2.3 2 1 0 2 2 2 1 MFS_1 like family EF-hand_1 PF00036.32 CBY08425.1 - 8.8e-17 59.3 8.6 1.1e-06 27.8 1.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY08425.1 - 2.7e-13 50.1 5.3 3.9e-06 27.2 1.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY08425.1 - 5e-13 47.8 6.4 4.1e-07 29.4 0.5 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBY08425.1 - 1.8e-08 34.1 9.2 0.0078 16.0 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY08425.1 - 3.7e-06 26.2 9.4 0.0011 18.3 0.8 3.1 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 CBY08425.1 - 0.0046 17.3 0.0 0.87 10.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 CBY08425.1 - 0.0053 17.6 0.1 0.018 15.9 0.1 1.8 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CBY08425.1 - 0.013 15.5 0.0 9.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 CBY08425.1 - 0.059 13.3 0.8 0.16 11.9 0.2 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand HEPN_RiboL-PSP PF18735.1 CBY08425.1 - 0.11 12.4 0.3 6 6.7 0.2 2.2 2 0 0 2 2 2 0 RiboL-PSP-HEPN SPARC_Ca_bdg PF10591.9 CBY08425.1 - 0.15 12.4 0.6 1.3 9.4 0.1 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PMP22_Claudin PF00822.20 CBY08426.1 - 7.4e-19 68.2 9.9 5e-17 62.3 9.9 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY08426.1 - 0.0027 17.5 12.0 0.47 10.2 12.0 2.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 CBY08426.1 - 0.04 13.4 0.9 0.13 11.8 0.3 2.0 2 0 0 2 2 2 0 Clc-like DUF2953 PF11167.8 CBY08426.1 - 3.3 7.9 6.3 24 5.1 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) FYVE PF01363.21 CBY08427.1 - 3.4e-05 23.9 6.7 6.6e-05 23.0 6.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CBY08427.1 - 4.1 7.7 18.2 0.36 11.0 10.7 2.7 3 1 0 3 3 3 0 FYVE-type zinc finger Flu_M1_C PF08289.11 CBY08428.1 - 0.32 11.2 2.2 0.61 10.3 1.4 1.7 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain T-box PF00907.22 CBY08429.1 - 5.6e-82 274.5 0.1 6.7e-82 274.2 0.1 1.1 1 0 0 1 1 1 1 T-box SPX PF03105.19 CBY08431.1 - 8.8 6.1 14.9 11 5.8 14.9 1.0 1 0 0 1 1 1 0 SPX domain Lipocalin_7 PF14651.6 CBY08433.1 - 6.5e-16 58.4 0.5 7.7e-16 58.2 0.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PK_C PF02887.16 CBY08433.1 - 0.0043 17.3 1.0 0.0046 17.2 0.3 1.4 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain SAP PF02037.27 CBY08434.1 - 3e-10 39.6 0.4 3e-10 39.6 0.4 2.0 2 0 0 2 2 2 1 SAP domain GAS PF13851.6 CBY08434.1 - 0.0042 16.5 13.1 0.0042 16.5 13.1 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Tautomerase PF01361.21 CBY08434.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Tautomerase enzyme VWA_3 PF13768.6 CBY08435.1 - 1.7e-06 28.1 0.0 1e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain CLP1_P PF16575.5 CBY08435.1 - 0.012 15.4 0.1 0.65 9.8 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APP_N PF02177.16 CBY08435.1 - 0.031 14.6 2.6 0.069 13.5 0.2 2.6 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding ABC_tran_CTD PF16326.5 CBY08436.1 - 0.12 12.6 0.2 0.12 12.6 0.2 5.6 4 2 2 6 6 6 0 ABC transporter C-terminal domain HDV_ag PF01517.18 CBY08436.1 - 5.8 6.7 7.3 4.6 7.0 1.5 2.7 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen COPIIcoated_ERV PF07970.12 CBY08437.1 - 1.6e-72 244.0 1.8 2.2e-72 243.5 1.8 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBY08437.1 - 9.9e-29 99.5 0.9 2.1e-28 98.5 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) LBR_tudor PF09465.10 CBY08437.1 - 0.13 12.1 0.0 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain PolC_DP2 PF03833.13 CBY08437.1 - 3.9 5.2 6.1 5.4 4.7 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_UBOX PF13445.6 CBY08438.1 - 6.9e-05 22.8 4.5 6.9e-05 22.8 4.5 3.7 3 0 0 3 3 3 1 RING-type zinc-finger ATG16 PF08614.11 CBY08438.1 - 0.00016 21.9 6.0 0.00025 21.4 6.0 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) zf-C3HC4_4 PF15227.6 CBY08438.1 - 0.0015 18.6 7.7 0.0015 18.6 7.7 3.9 4 2 0 4 4 3 1 zinc finger of C3HC4-type, RING Zn-C2H2_12 PF18112.1 CBY08438.1 - 0.002 18.5 5.5 0.039 14.4 0.4 3.4 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain Exonuc_VII_L PF02601.15 CBY08438.1 - 0.012 15.2 4.2 0.016 14.8 4.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BST2 PF16716.5 CBY08438.1 - 0.013 16.1 5.8 0.04 14.5 5.8 1.9 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Zn_ribbon_recom PF13408.6 CBY08438.1 - 0.049 14.2 0.1 0.049 14.2 0.1 3.2 2 1 0 2 2 1 0 Recombinase zinc beta ribbon domain DUF4407 PF14362.6 CBY08438.1 - 0.14 11.5 0.9 0.2 11.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CBY08438.1 - 0.15 12.7 1.2 0.3 11.8 1.0 1.6 1 1 0 1 1 1 0 SlyX LMBR1 PF04791.16 CBY08438.1 - 0.18 10.7 0.3 0.17 10.8 0.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 CBY08438.1 - 0.23 10.3 14.2 0.39 9.6 14.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4094 PF13334.6 CBY08438.1 - 0.29 11.6 3.0 0.78 10.2 3.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CaKB PF03185.15 CBY08438.1 - 0.39 10.4 4.7 0.91 9.2 4.7 1.5 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit FRG1 PF06229.12 CBY08438.1 - 0.49 10.1 7.9 0.88 9.3 7.9 1.4 1 0 0 1 1 1 0 FRG1-like domain zf-C3HC4 PF00097.25 CBY08438.1 - 0.53 10.2 20.9 0.85 9.5 16.1 3.6 2 1 2 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF3450 PF11932.8 CBY08438.1 - 0.82 8.9 7.3 1.4 8.2 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 CBY08438.1 - 1.1 8.4 7.3 1.7 7.8 7.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein HemX PF04375.14 CBY08438.1 - 1.7 7.9 7.7 1.2 8.3 6.2 1.4 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase CENP-H PF05837.12 CBY08438.1 - 1.8 9.0 13.6 2 8.9 12.3 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) zf-RING_2 PF13639.6 CBY08438.1 - 4.8 7.6 24.7 2.8 8.3 16.2 3.9 3 1 0 3 3 3 0 Ring finger domain ALMT PF11744.8 CBY08438.1 - 5.8 5.6 8.3 7.7 5.2 8.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0242 PF06785.11 CBY08438.1 - 8.6 6.4 16.0 21 5.1 16.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Clathrin_lg_ch PF01086.17 CBY08440.1 - 0.66 10.0 14.5 0.12 12.4 9.9 1.7 1 1 1 2 2 2 0 Clathrin light chain rRNA_processing PF08524.11 CBY08440.1 - 3.7 7.6 11.9 0.33 11.0 1.4 2.2 1 1 1 2 2 2 0 rRNA processing Tcf25 PF04910.14 CBY08441.1 - 6.6e-63 212.9 0.0 9.6e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PGA2 PF07543.12 CBY08441.1 - 0.016 15.2 5.7 0.037 14.0 5.7 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 GET2 PF08690.10 CBY08441.1 - 1.3 8.7 12.1 0.13 11.9 6.7 1.9 2 0 0 2 2 2 0 GET complex subunit GET2 AAA_23 PF13476.6 CBY08442.1 - 4.2e-25 89.4 9.1 4.2e-25 89.4 9.1 8.1 1 1 3 4 4 4 1 AAA domain AAA_15 PF13175.6 CBY08442.1 - 5.7e-10 39.4 37.9 1.3e-06 28.4 12.7 5.1 1 1 3 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 CBY08442.1 - 7e-07 29.3 1.3 0.0001 22.2 0.3 4.6 4 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY08442.1 - 1.3e-05 24.7 0.0 1.3e-05 24.7 0.0 5.0 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CBY08442.1 - 3.6e-05 23.9 0.1 0.0001 22.4 0.1 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CBY08442.1 - 0.00032 20.4 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 CBY08442.1 - 0.016 15.2 4.6 0.17 11.9 0.1 3.8 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) TMP_2 PF06791.13 CBY08442.1 - 0.12 12.0 0.7 0.35 10.5 0.7 1.7 1 0 0 1 1 1 0 Prophage tail length tape measure protein AAA_13 PF13166.6 CBY08442.1 - 0.16 10.6 0.0 0.16 10.6 0.0 7.6 3 1 2 6 6 6 0 AAA domain AAA_16 PF13191.6 CBY08442.1 - 0.27 11.6 0.0 0.27 11.6 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain RNase_H PF00075.24 CBY08443.1 - 6.6e-26 91.2 0.1 8.5e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CBY08443.1 - 7e-05 22.6 0.0 0.0066 16.3 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase-like SET PF00856.28 CBY08445.1 - 1.4e-25 90.6 5.1 6.3e-25 88.5 5.1 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 CBY08445.1 - 7.3e-12 45.9 8.7 7.3e-12 45.9 8.7 2.6 3 0 0 3 3 3 1 Pre-SET motif TUDOR_5 PF18359.1 CBY08445.1 - 0.04 13.6 0.0 0.13 12.0 0.0 2.0 1 1 0 1 1 1 0 Histone methyltransferase Tudor domain 1 DUF3603 PF12227.8 CBY08445.1 - 0.053 12.8 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Dynein_attach_N PF15867.5 CBY08446.1 - 6.5e-24 83.7 1.2 1.5e-22 79.3 0.2 2.8 3 0 0 3 3 3 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 CBY08446.1 - 9.8e-07 29.2 0.3 2.3e-06 28.1 0.3 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Methyltransf_14 PF08484.11 CBY08446.1 - 0.011 15.5 0.1 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain TAFII55_N PF04658.13 CBY08447.1 - 1e-43 148.9 3.5 1e-43 148.9 3.5 2.7 2 2 0 2 2 2 1 TAFII55 protein conserved region Hid1 PF12722.7 CBY08448.1 - 1.1e-209 698.6 2.1 1.4e-209 698.2 2.1 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CBY08448.1 - 1.4e-176 588.7 3.0 1.7e-176 588.4 3.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein ImpE PF07024.13 CBY08448.1 - 0.031 14.4 0.0 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 ImpE protein BAH PF01426.18 CBY08449.1 - 3.4e-27 94.7 0.5 1.2e-26 93.0 0.5 2.0 1 0 0 1 1 1 1 BAH domain MTA_R1 PF17226.2 CBY08449.1 - 5.8e-09 36.0 2.3 3.6e-07 30.2 0.1 3.2 3 0 0 3 3 3 1 MTA R1 domain ELM2 PF01448.24 CBY08449.1 - 5.4e-05 23.9 0.0 5.4e-05 23.9 0.0 3.5 4 1 0 4 4 4 1 ELM2 domain FAD_binding_8 PF08022.12 CBY08449.1 - 0.36 11.0 2.1 1.9e+02 2.2 0.3 3.9 4 0 0 4 4 4 0 FAD-binding domain Kinesin PF00225.23 CBY08450.1 - 2e-107 359.0 0.4 2e-107 359.0 0.4 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY08450.1 - 5.4e-26 91.3 0.1 5.4e-26 91.3 0.1 2.8 2 1 0 2 2 2 1 Microtubule binding UPF0242 PF06785.11 CBY08450.1 - 0.003 17.7 28.5 0.003 17.7 28.5 5.6 3 2 1 5 5 5 2 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 CBY08450.1 - 1.5 8.6 90.6 0.12 12.2 18.7 4.4 3 1 0 4 4 4 0 Ezrin/radixin/moesin family SRP54 PF00448.22 CBY08451.1 - 1.6e-50 171.5 0.0 4.1e-50 170.1 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CBY08451.1 - 1.3e-35 123.8 20.4 8.5e-35 121.1 20.4 1.9 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CBY08451.1 - 1.1e-11 44.8 0.3 3.9e-11 43.0 0.3 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 CBY08451.1 - 5.4e-07 29.7 0.0 0.082 13.0 0.0 3.3 3 1 0 3 3 3 2 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 CBY08451.1 - 1.5e-06 27.4 0.8 2.7e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 CBY08451.1 - 0.00016 21.0 0.1 0.00054 19.3 0.0 1.9 2 0 0 2 2 2 1 VirC1 protein NTPase_1 PF03266.15 CBY08451.1 - 0.0034 17.3 0.0 0.11 12.4 0.0 2.5 1 1 0 1 1 1 1 NTPase Fer4_NifH PF00142.18 CBY08451.1 - 0.0076 15.7 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 CBY08451.1 - 0.0094 16.3 0.0 0.038 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CBY08451.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain T3SS_needle_reg PF09025.10 CBY08451.1 - 0.069 13.1 1.0 3.6 7.6 0.3 2.4 2 0 0 2 2 2 0 YopR, type III needle-polymerisation regulator MMR_HSR1 PF01926.23 CBY08451.1 - 0.1 12.7 0.5 0.92 9.6 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_31 PF13614.6 CBY08451.1 - 0.14 12.0 3.0 5.9 6.8 0.0 3.4 3 1 0 4 4 4 0 AAA domain Sas10_Utp3 PF04000.15 CBY08452.1 - 1.1e-10 42.0 1.4 1.7e-10 41.4 1.4 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family TRPM_tetra PF16519.5 CBY08452.1 - 0.0096 16.0 0.8 0.25 11.5 0.1 2.3 2 0 0 2 2 2 1 Tetramerisation domain of TRPM CENP-F_leu_zip PF10473.9 CBY08452.1 - 0.015 15.3 6.1 0.045 13.8 1.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 CBY08452.1 - 0.022 15.2 4.6 0.38 11.3 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.9 CBY08452.1 - 0.16 11.9 0.3 0.68 9.9 0.0 2.0 1 1 1 2 2 2 0 Apolipoprotein O BRE1 PF08647.11 CBY08452.1 - 0.37 10.9 8.8 2.9 8.0 2.5 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase zf-met PF12874.7 CBY08453.1 - 0.00028 21.2 0.1 0.00066 20.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CBY08453.1 - 0.0014 19.0 0.3 0.004 17.5 0.3 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY08453.1 - 0.0024 18.5 0.2 0.011 16.5 0.2 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger DIT1_PvcA PF05141.12 CBY08453.1 - 0.022 14.2 1.1 0.034 13.6 0.2 1.6 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein zf-C2H2_jaz PF12171.8 CBY08453.1 - 0.042 14.2 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding LicD PF04991.13 CBY08453.1 - 0.51 10.4 3.1 0.83 9.7 3.1 1.4 1 0 0 1 1 1 0 LicD family Frtz PF11768.8 CBY08454.1 - 8.4e-62 209.2 4.4 1.8e-58 198.2 0.8 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 CBY08454.1 - 0.066 13.5 0.0 8.4 6.8 0.0 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain MT-A70 PF05063.14 CBY08455.1 - 1.4e-50 171.5 0.0 2.1e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Hypoth_Ymh PF09509.10 CBY08456.1 - 0.0024 17.8 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (Hypoth_ymh) TM_PBP2_N PF16296.5 CBY08456.1 - 0.069 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters VCBS PF13517.6 CBY08457.1 - 0.045 14.3 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBY08457.1 - 0.15 12.2 0.3 0.35 11.0 0.3 1.5 1 0 0 1 1 1 0 FG-GAP repeat DUF1967 PF09269.11 CBY08458.1 - 0.025 14.5 0.8 0.025 14.5 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) Abi_C PF14355.6 CBY08458.1 - 0.064 13.4 0.8 0.23 11.6 0.1 2.3 2 0 0 2 2 2 0 Abortive infection C-terminus RRM_1 PF00076.22 CBY08459.1 - 2.9e-18 65.4 0.0 4.3e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY08459.1 - 4.9e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 CBY08460.1 - 7.3e-17 61.0 0.2 1.4e-16 60.1 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY08460.1 - 2.1e-05 24.6 0.1 5.7e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif NupH_GANP PF16768.5 CBY08460.1 - 0.012 15.3 1.8 0.018 14.7 1.8 1.2 1 0 0 1 1 1 0 Nucleoporin homology of Germinal-centre associated nuclear protein ThylakoidFormat PF11264.8 CBY08460.1 - 0.062 13.0 0.4 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 Thylakoid formation protein APG6_N PF17675.1 CBY08461.1 - 0.00056 20.4 4.5 0.00056 20.4 4.5 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region Shugoshin_N PF07558.11 CBY08461.1 - 0.0032 17.3 1.9 0.0094 15.8 1.9 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Peptidase_S49_N PF08496.10 CBY08461.1 - 0.077 13.1 5.9 0.11 12.5 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3450 PF11932.8 CBY08461.1 - 0.55 9.5 8.9 0.76 9.0 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 CBY08461.1 - 0.7 10.3 10.8 1.2 9.6 10.8 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc24 PF08286.11 CBY08461.1 - 7 7.0 10.0 4 7.7 7.7 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SNF PF00209.18 CBY08462.1 - 3e-169 564.1 39.0 7.7e-169 562.7 39.0 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family GAGA_bind PF06217.12 CBY08462.1 - 0.55 10.5 2.0 0.86 9.8 2.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ion_trans PF00520.31 CBY08463.1 - 9.3e-24 84.0 13.1 1.3e-23 83.6 13.1 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY08463.1 - 7.8e-19 67.5 0.0 1.5e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.10 CBY08463.1 - 3.6e-14 52.1 0.1 7.4e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans_2 PF07885.16 CBY08463.1 - 0.0081 16.1 2.4 0.024 14.6 0.0 2.7 2 0 0 2 2 2 1 Ion channel Mltc_N PF11873.8 CBY08464.1 - 0.22 11.3 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain Galactosyl_T PF01762.21 CBY08465.1 - 1.3e-20 74.1 0.0 2.7e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase G-alpha PF00503.20 CBY08466.1 - 3.1e-20 72.6 0.5 4.4e-20 72.1 0.5 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY08466.1 - 0.0029 17.1 0.1 0.0053 16.2 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-C3HC4_3 PF13920.6 CBY08467.1 - 0.0012 18.7 10.2 0.0035 17.2 10.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Bcr-Abl_Oligo PF09036.10 CBY08467.1 - 0.0021 18.0 1.6 0.006 16.6 1.6 1.8 1 0 0 1 1 1 1 Bcr-Abl oncoprotein oligomerisation domain zf-C3HC4_2 PF13923.6 CBY08467.1 - 0.0032 17.3 12.3 0.0078 16.0 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CBY08467.1 - 0.0056 16.6 9.4 0.0056 16.6 9.4 2.2 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 CBY08467.1 - 0.039 13.8 3.5 0.11 12.4 3.5 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Fungal_TACC PF12709.7 CBY08467.1 - 0.11 12.9 6.5 0.39 11.2 6.5 1.9 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins zf-P11 PF03854.14 CBY08467.1 - 0.75 9.5 8.0 2.4 7.9 8.0 1.9 1 0 0 1 1 1 0 P-11 zinc finger Phage_HK97_TLTM PF06120.11 CBY08467.1 - 1.1 8.4 9.7 0.082 12.1 3.9 1.9 2 0 0 2 2 2 0 Tail length tape measure protein zf-RING_5 PF14634.6 CBY08467.1 - 1.3 9.1 15.4 0.89 9.6 12.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY08467.1 - 3 7.8 18.3 0.18 11.7 11.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fzo_mitofusin PF04799.13 CBY08467.1 - 7.6 6.1 6.5 5.3 6.6 0.2 2.4 2 0 0 2 2 2 0 fzo-like conserved region Molybdopterin PF00384.22 CBY08468.1 - 5.3e-49 167.3 0.0 3.2e-47 161.5 0.0 2.7 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 CBY08468.1 - 1.4e-07 32.1 0.1 2.9e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal TPP_enzyme_M PF00205.22 CBY08468.1 - 0.03 14.1 0.0 3.1 7.5 0.0 3.5 3 1 1 4 4 4 0 Thiamine pyrophosphate enzyme, central domain Ion_trans PF00520.31 CBY08471.1 - 6.8e-224 739.4 84.3 2.4e-63 213.7 9.5 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CBY08471.1 - 3.2e-13 49.2 92.4 3.7e-06 25.9 3.9 10.7 6 4 4 10 10 10 7 Polycystin cation channel GPHH PF16905.5 CBY08471.1 - 0.00016 21.3 0.0 0.00059 19.5 0.0 2.0 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 CBY08471.1 - 0.018 14.8 0.4 0.047 13.5 0.4 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ly49 PF08391.10 CBY08471.1 - 0.019 15.3 0.4 8.5 6.8 0.1 3.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region UPF0542 PF15086.6 CBY08471.1 - 0.41 10.6 4.5 0.34 10.8 0.2 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 Hormone_recep PF00104.30 CBY08472.1 - 3.8e-15 56.0 1.6 6.1e-15 55.4 1.6 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CBY08473.1 - 1.7e-28 98.9 17.9 1.7e-28 98.9 17.9 1.4 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) DUF2623 PF11115.8 CBY08473.1 - 0.13 12.4 2.3 0.2 11.8 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2623) RRM_1 PF00076.22 CBY08476.1 - 2.4e-33 113.8 0.0 2e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY08476.1 - 1.8e-08 34.4 0.1 0.00032 20.8 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CBY08476.1 - 0.081 13.2 5.4 0.98 9.6 0.3 3.0 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DUF4283 PF14111.6 CBY08476.1 - 0.14 11.6 0.0 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) Prenyltrans PF00432.21 CBY08478.1 - 3.2e-30 103.6 5.9 4.2e-07 29.6 0.0 6.6 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat NOC3p PF07540.11 CBY08478.1 - 0.017 15.6 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Nucleolar complex-associated protein SQHop_cyclase_N PF13249.6 CBY08478.1 - 0.081 12.0 0.0 0.47 9.5 0.0 2.0 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Phospho_p8 PF10195.9 CBY08479.1 - 1.3e-06 28.8 0.1 1.4e-06 28.7 0.1 1.3 1 1 0 1 1 1 1 DNA-binding nuclear phosphoprotein p8 Proteasome PF00227.26 CBY08480.1 - 1.3e-34 119.3 0.0 1.9e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit MFAP1 PF06991.11 CBY08481.1 - 3e-65 220.1 28.6 3e-65 220.1 28.6 2.2 2 0 0 2 2 2 2 Microfibril-associated/Pre-mRNA processing Ribosomal_L37e PF01907.19 CBY08482.1 - 6.9e-09 35.7 5.3 5.2e-08 32.9 5.3 2.1 1 1 0 1 1 1 1 Ribosomal protein L37e PUA PF01472.20 CBY08483.1 - 1.5e-07 31.3 0.1 2.1e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 PUA domain SUI1 PF01253.22 CBY08484.1 - 3.5e-16 59.5 0.1 6.9e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ureide_permease PF07168.11 CBY08484.1 - 0.22 10.3 2.2 0.35 9.6 2.2 1.3 1 0 0 1 1 1 0 Ureide permease SEA PF01390.20 CBY08485.1 - 0.013 15.6 0.3 0.013 15.6 0.3 5.9 6 2 2 8 8 8 0 SEA domain NOT2_3_5 PF04153.18 CBY08487.1 - 3.5e-26 91.8 5.6 4.7e-26 91.4 5.6 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family IKI3 PF04762.12 CBY08488.1 - 1.4e-82 278.2 0.1 3.1e-58 197.6 0.1 2.0 1 1 0 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 CBY08488.1 - 0.15 12.4 0.1 76 3.7 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CBY08489.1 - 6.1e-18 64.3 5.2 1.1e-17 63.5 5.2 1.4 1 0 0 1 1 1 1 IKI3 family DcpS_C PF11969.8 CBY08490.1 - 1.3e-20 74.0 0.0 1.5e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CBY08490.1 - 0.0016 19.2 0.0 0.0026 18.5 0.0 1.3 1 0 0 1 1 1 1 HIT domain CDH PF02611.15 CBY08490.1 - 0.043 13.4 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase WD40 PF00400.32 CBY08491.1 - 6e-05 23.7 6.4 0.13 13.2 1.2 4.6 3 1 0 3 3 3 2 WD domain, G-beta repeat Ras PF00071.22 CBY08492.1 - 5.7e-63 211.4 0.2 6.6e-63 211.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY08492.1 - 8e-36 122.9 0.1 1.3e-35 122.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY08492.1 - 3.6e-13 49.3 0.1 4.7e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY08492.1 - 9.5e-08 32.1 0.1 1.4e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY08492.1 - 8.6e-05 22.2 0.2 0.00054 19.6 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY08492.1 - 0.00012 22.1 0.2 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CBY08492.1 - 0.00042 20.6 0.1 0.0066 16.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 CBY08492.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBY08492.1 - 0.0089 15.5 0.0 0.023 14.2 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CBY08492.1 - 0.011 16.1 0.1 0.019 15.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 CBY08492.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CBY08492.1 - 0.016 15.8 0.2 0.029 14.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CBY08492.1 - 0.016 15.2 0.1 0.049 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBY08492.1 - 0.053 13.3 0.1 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 CBY08492.1 - 0.067 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 CBY08492.1 - 0.07 12.7 0.1 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 CBY08492.1 - 0.16 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Tetraspanin PF00335.20 CBY08493.1 - 1.7e-53 181.7 7.8 2e-53 181.5 7.8 1.0 1 0 0 1 1 1 1 Tetraspanin family Adeno_E3B PF03376.14 CBY08493.1 - 1.5 9.1 4.8 1.5 9.1 0.2 2.8 3 0 0 3 3 3 0 Adenovirus E3B protein DctQ PF04290.12 CBY08493.1 - 3.7 7.5 8.1 0.38 10.7 1.4 2.4 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF4199 PF13858.6 CBY08493.1 - 6.4 7.1 13.5 0.62 10.4 8.6 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) RRM_1 PF00076.22 CBY08494.1 - 2.9e-13 49.4 0.0 5.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY08494.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Codanin-1_C PF15296.6 CBY08494.1 - 0.084 12.9 0.1 0.084 12.9 0.1 3.0 1 1 1 2 2 2 0 Codanin-1 C-terminus Nup35_RRM_2 PF14605.6 CBY08494.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Med19 PF10278.9 CBY08494.1 - 0.35 10.8 17.1 0.41 10.6 13.4 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Neur_chan_memb PF02932.16 CBY08494.1 - 1.5 8.8 7.1 2.2 8.3 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.22 CBY08495.1 - 5.5e-24 84.6 0.1 9.4e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY08495.1 - 4.2e-07 30.2 0.1 1.3e-06 28.6 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY08495.1 - 0.00017 21.1 0.1 0.0019 17.7 0.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY08495.1 - 0.045 13.8 0.4 0.19 11.8 0.1 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF3665 PF12427.8 CBY08495.1 - 0.37 10.5 2.6 0.81 9.4 2.6 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Calc_CGRP_IAPP PF00214.19 CBY08495.1 - 0.56 10.6 2.5 0.82 10.0 0.9 2.1 2 1 0 2 2 2 0 Calcitonin / CGRP / IAPP family Sulfotransfer_2 PF03567.14 CBY08498.1 - 2.7e-10 40.6 1.2 4.8e-10 39.8 1.2 1.4 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 CBY08498.1 - 0.0016 17.4 0.1 0.0033 16.4 0.0 1.6 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase Trypsin PF00089.26 CBY08499.1 - 5.3e-55 186.6 0.3 5.3e-55 186.6 0.3 1.8 2 0 0 2 2 2 1 Trypsin Pro_isomerase PF00160.21 CBY08499.1 - 1.3e-41 142.6 0.1 2.8e-41 141.4 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trypsin_2 PF13365.6 CBY08499.1 - 2.4e-06 28.5 0.0 6.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain O-FucT PF10250.9 CBY08500.1 - 1.4e-11 44.7 0.0 2.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Peptidase_M1 PF01433.20 CBY08501.1 - 2e-33 115.8 0.6 3.2e-33 115.1 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Pkinase PF00069.25 CBY08502.1 - 6.1e-19 68.4 0.0 9e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08502.1 - 8.7e-07 28.5 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Yip1 PF04893.17 CBY08503.1 - 2.5e-11 43.6 11.3 2.5e-11 43.6 11.3 1.7 1 1 1 2 2 2 1 Yip1 domain DUF2070 PF09843.9 CBY08503.1 - 8.1 4.6 7.9 11 4.2 7.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MMS19_C PF12460.8 CBY08504.1 - 5.8e-34 117.9 4.5 5.8e-34 117.9 4.5 1.4 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CBY08504.1 - 0.077 12.6 0.4 0.3 10.6 0.1 1.8 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Mo25 PF08569.11 CBY08504.1 - 0.11 11.9 0.3 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Mo25-like HEAT_EZ PF13513.6 CBY08504.1 - 0.12 12.9 4.7 2.6 8.7 0.4 3.3 1 1 2 3 3 3 0 HEAT-like repeat MucBP PF06458.12 CBY08506.1 - 0.074 14.1 0.1 0.2 12.7 0.1 1.8 1 0 0 1 1 1 0 MucBP domain zf-C2H2 PF00096.26 CBY08507.1 - 5.5e-25 86.4 51.0 1.1e-05 25.6 2.7 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY08507.1 - 6.3e-19 67.5 54.5 7.2e-08 32.5 1.2 6.8 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY08507.1 - 3.1e-15 55.7 43.0 4.2e-06 26.6 0.6 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CBY08507.1 - 9.5e-15 54.0 50.2 0.0055 17.4 2.3 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2HE PF16278.5 CBY08507.1 - 0.01 16.3 33.0 0.078 13.4 1.1 5.6 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 CBY08507.1 - 0.017 15.0 0.2 0.017 15.0 0.2 6.3 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-met PF12874.7 CBY08507.1 - 0.019 15.3 30.1 0.03 14.7 0.6 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type TFIIA PF03153.13 CBY08507.1 - 0.021 14.8 11.3 0.05 13.6 11.3 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_11 PF16622.5 CBY08507.1 - 0.026 14.3 1.0 0.026 14.3 1.0 5.1 6 0 0 6 6 5 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CBY08507.1 - 0.063 13.6 1.1 0.063 13.6 1.1 6.3 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding BolA PF01722.18 CBY08507.1 - 0.14 12.5 7.6 0.96 9.8 1.3 3.6 2 2 1 3 3 3 0 BolA-like protein Zn-ribbon_8 PF09723.10 CBY08507.1 - 0.51 10.5 23.6 0.67 10.1 1.0 4.7 3 3 2 5 5 5 0 Zinc ribbon domain zf-CHCC PF10276.9 CBY08507.1 - 0.53 10.4 16.2 7.8 6.6 0.1 5.1 5 0 0 5 5 5 0 Zinc-finger domain START PF01852.19 CBY08509.1 - 4e-20 72.1 0.0 4.6e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 START domain Rhamnogal_lyase PF06045.11 CBY08509.1 - 0.012 15.0 0.6 0.019 14.4 0.5 1.4 1 1 0 1 1 1 0 Rhamnogalacturonate lyase family Glyoxalase_4 PF13669.6 CBY08511.1 - 1.1e-20 73.9 0.0 1.4e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 CBY08511.1 - 8.4e-13 48.6 0.0 9.1e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CBY08511.1 - 1.8e-07 31.4 0.0 2.2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 CBY08511.1 - 0.00063 20.5 0.0 0.00083 20.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CBY08511.1 - 0.12 12.3 0.0 0.42 10.6 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain SNF2_N PF00176.23 CBY08512.1 - 3.6e-54 183.8 0.3 8.9e-54 182.5 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY08512.1 - 4.8e-12 46.2 0.0 7e-11 42.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Feld-I_B PF09252.10 CBY08512.1 - 0.058 13.3 0.1 0.23 11.4 0.1 2.0 1 0 0 1 1 1 0 Allergen Fel d I-B chain RRM_1 PF00076.22 CBY08513.1 - 6.9e-09 35.4 0.1 5.2e-08 32.6 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY08513.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Innexin PF00876.18 CBY08514.1 - 0.002 17.5 2.8 0.0028 17.0 2.6 1.4 1 1 0 1 1 1 1 Innexin ASC PF00858.24 CBY08515.1 - 1.5e-13 50.6 0.1 1.7e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel bZIP_1 PF00170.21 CBY08516.1 - 7.5e-09 35.6 19.8 1.2e-08 34.9 19.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CBY08516.1 - 2.3e-08 34.4 11.6 3.6e-08 33.8 11.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CBY08516.1 - 7.5e-07 29.1 22.3 7.5e-07 29.1 22.3 1.6 2 0 0 2 2 1 1 Basic region leucine zipper UPF0242 PF06785.11 CBY08516.1 - 0.00066 19.8 3.9 0.00096 19.3 3.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 CBY08516.1 - 0.0016 18.8 2.7 0.0028 18.0 2.7 1.4 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) YabA PF06156.13 CBY08516.1 - 0.045 14.4 1.9 0.077 13.6 1.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA JIP_LZII PF16471.5 CBY08516.1 - 0.048 13.8 5.8 0.088 13.0 5.8 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II SHE3 PF17078.5 CBY08516.1 - 0.05 13.3 6.9 0.07 12.8 6.9 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.15 CBY08516.1 - 0.079 12.7 5.2 0.19 11.6 5.2 1.6 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 CBY08516.1 - 0.1 12.9 6.2 0.24 11.6 6.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Spc24 PF08286.11 CBY08516.1 - 0.13 12.5 2.6 0.22 11.8 2.6 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Tox-ODYAM1 PF15642.6 CBY08516.1 - 0.55 9.2 4.6 0.74 8.7 4.6 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus VGCC_beta4Aa_N PF12052.8 CBY08516.1 - 0.75 9.9 15.8 0.27 11.4 6.7 2.6 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal MctB PF11382.8 CBY08516.1 - 0.83 9.3 2.0 1.2 8.8 2.0 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB CCDC-167 PF15188.6 CBY08516.1 - 1.9 8.9 9.8 1.6 9.1 8.2 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Bap31_Bap29_C PF18035.1 CBY08516.1 - 2.3 8.3 11.6 3.9 7.5 8.2 2.2 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Med21 PF11221.8 CBY08516.1 - 8.8 6.6 11.5 2.6 8.3 8.0 1.9 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Herpes_UL82_83 PF05784.11 CBY08518.1 - 0.071 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus Sugar_tr PF00083.24 CBY08519.1 - 6.5e-18 64.8 24.9 1.1e-16 60.8 19.2 3.3 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 CBY08519.1 - 1.4e-12 47.3 22.2 1.4e-12 47.3 22.2 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 CBY08519.1 - 0.0028 16.2 3.2 0.0054 15.2 3.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hydrolase_4 PF12146.8 CBY08520.1 - 1.2e-06 27.9 0.0 9.5e-05 21.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY08520.1 - 5.7e-05 22.9 0.6 0.00073 19.2 0.3 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY08520.1 - 0.00021 22.0 0.7 0.00036 21.2 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DDE_Tnp_ISL3 PF01610.17 CBY08520.1 - 0.014 15.1 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Transposase Dynein_light PF01221.18 CBY08521.1 - 1.5e-33 115.0 1.7 2.3e-33 114.4 1.0 1.5 1 1 1 2 2 2 1 Dynein light chain type 1 IgG_binding_B PF01378.17 CBY08521.1 - 0.04 14.0 1.1 0.98 9.5 0.3 2.3 1 1 1 2 2 2 0 B domain BetaGal_dom4_5 PF13364.6 CBY08523.1 - 0.0033 18.0 0.1 0.0062 17.1 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_35 PF01301.19 CBY08524.1 - 2.6e-101 339.4 2.9 3.1e-101 339.1 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY08524.1 - 7.6e-14 51.8 0.5 3e-13 49.9 0.0 2.1 2 1 0 2 2 2 1 Beta-galactosidase Amidohydro_2 PF04909.14 CBY08524.1 - 0.0031 17.4 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Trefoil PF00088.18 CBY08526.1 - 5.1e-13 48.7 36.0 0.00012 21.9 4.9 3.5 3 0 0 3 3 3 3 Trefoil (P-type) domain TEX29 PF15839.5 CBY08526.1 - 0.037 14.6 23.0 0.74 10.5 3.1 3.8 2 1 2 4 4 4 0 Testis-expressed sequence 29 protein Gp58 PF07902.11 CBY08529.1 - 0.023 13.0 0.1 0.029 12.7 0.1 1.1 1 0 0 1 1 1 0 gp58-like protein Exonuc_VII_L PF02601.15 CBY08529.1 - 0.14 11.7 7.5 0.17 11.4 7.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 CBY08529.1 - 0.3 10.3 8.9 0.43 9.8 8.9 1.5 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 CBY08529.1 - 0.5 10.4 20.8 1.6 8.8 20.7 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CBY08529.1 - 0.69 10.0 4.8 1.8 8.7 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_11 PF13086.6 CBY08529.1 - 0.97 9.2 10.3 1.6 8.4 10.3 1.3 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 CBY08529.1 - 2.4 6.0 10.4 3 5.7 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CBY08529.1 - 4.5 6.5 14.7 6.2 6.1 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ureide_permease PF07168.11 CBY08529.1 - 4.6 5.9 4.7 6.7 5.3 4.7 1.1 1 0 0 1 1 1 0 Ureide permease C2 PF00168.30 CBY08530.1 - 1.7e-20 73.2 0.0 3.5e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.6 CBY08530.1 - 0.017 14.9 0.0 0.59 9.9 0.0 2.7 2 1 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins DUF1640 PF07798.11 CBY08531.1 - 0.014 15.5 0.5 0.19 11.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) SIT PF15330.6 CBY08531.1 - 0.057 13.9 0.1 0.068 13.6 0.1 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Glyco_transf_90 PF05686.12 CBY08532.1 - 4.4e-32 111.5 0.2 5.3e-32 111.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 DUF4534 PF15049.6 CBY08533.1 - 0.046 13.5 7.3 1.9 8.2 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) DUF4064 PF13273.6 CBY08533.1 - 0.064 13.5 9.7 0.26 11.6 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SfLAP PF11139.8 CBY08533.1 - 0.23 10.8 3.7 0.25 10.8 0.3 2.0 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein Pkinase PF00069.25 CBY08534.1 - 0.0017 17.8 0.7 0.0043 16.4 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Nsp1_C PF05064.13 CBY08534.1 - 0.007 16.2 2.6 0.069 13.0 1.2 2.4 2 0 0 2 2 2 1 Nsp1-like C-terminal region TPR_MLP1_2 PF07926.12 CBY08534.1 - 0.045 13.8 9.7 0.63 10.1 6.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 CBY08534.1 - 0.092 12.8 13.2 0.34 11.0 0.4 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_9 PF12781.7 CBY08534.1 - 0.11 11.7 2.4 0.19 10.8 0.7 2.0 2 0 0 2 2 2 0 ATP-binding dynein motor region Syntaxin PF00804.25 CBY08534.1 - 0.26 10.9 11.7 0.023 14.4 3.1 2.2 1 1 1 2 2 2 0 Syntaxin DUF2203 PF09969.9 CBY08534.1 - 0.34 11.6 3.6 5.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) MAT1 PF06391.13 CBY08534.1 - 0.5 10.2 11.8 0.15 11.9 6.9 2.0 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4472 PF14739.6 CBY08534.1 - 0.89 10.3 8.2 17 6.2 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) HIP1_clath_bdg PF16515.5 CBY08534.1 - 1.1 9.9 13.7 0.68 10.6 0.1 2.6 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 CBY08534.1 - 2.3 8.5 8.9 3.3 8.0 1.9 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RmuC PF02646.16 CBY08534.1 - 2.3 7.3 8.4 0.53 9.4 0.2 2.2 1 1 1 2 2 2 0 RmuC family DUF16 PF01519.16 CBY08534.1 - 3.5 8.2 10.9 8.5 6.9 5.7 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4600 PF15372.6 CBY08534.1 - 3.5 8.1 10.8 19 5.7 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) Syntaxin-6_N PF09177.11 CBY08534.1 - 5.6 7.6 11.6 20 5.8 1.5 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 CBY08534.1 - 7.3 5.8 12.0 12 5.1 12.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 CBY08534.1 - 9.8 5.4 12.2 1.8 7.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Pkinase PF00069.25 CBY08535.1 - 3.1e-50 171.0 0.0 4e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08535.1 - 4.8e-23 81.8 0.0 6.3e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY08535.1 - 1e-05 25.0 0.0 0.0001 21.7 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY08535.1 - 5.5e-05 22.9 0.1 8.1e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Trefoil PF00088.18 CBY08537.1 - 1.4e-19 69.7 8.7 1.4e-10 40.9 1.7 2.3 2 0 0 2 2 2 2 Trefoil (P-type) domain NAAA-beta PF15508.6 CBY08538.1 - 0.093 13.1 0.3 0.51 10.7 0.1 2.1 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Endonuclease_NS PF01223.23 CBY08543.1 - 5.6e-25 88.5 4.9 2.1e-24 86.6 4.9 1.7 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 CBY08543.1 - 0.013 15.6 0.2 0.03 14.4 0.2 1.6 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease DUF4762 PF15959.5 CBY08543.1 - 0.028 14.4 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4762) Ceramidase PF05875.12 CBY08543.1 - 0.047 13.1 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Ceramidase Pox_F15 PF04596.12 CBY08543.1 - 0.051 13.3 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus protein F15 O-FucT PF10250.9 CBY08546.1 - 1.2e-05 25.3 0.9 3.8e-05 23.6 0.9 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase dCMP_cyt_deam_1 PF00383.23 CBY08547.1 - 3.9e-13 49.1 0.2 1.1e-12 47.6 0.2 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBY08547.1 - 3.2e-07 30.6 1.3 1.1e-06 28.8 0.3 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CBY08547.1 - 0.02 14.5 1.7 1.1 8.9 0.2 2.3 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PhaC_N PF07167.13 CBY08547.1 - 0.098 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Pou PF00157.17 CBY08549.1 - 1.9e-37 127.1 0.1 5.8e-37 125.5 0.0 1.9 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY08549.1 - 1.4e-12 47.3 1.1 2.6e-12 46.4 0.4 1.9 2 0 0 2 2 2 1 Homeodomain Mfa1 PF17445.2 CBY08549.1 - 0.0069 16.4 1.6 0.031 14.3 1.6 2.1 1 0 0 1 1 1 1 Mating factor A1 Tropomyosin_1 PF12718.7 CBY08550.1 - 0.0099 16.0 20.2 0.0099 16.0 20.2 7.0 2 1 3 6 6 6 1 Tropomyosin like Ion_trans_2 PF07885.16 CBY08551.1 - 2.4e-16 59.4 0.5 3.3e-16 59.0 0.5 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CBY08551.1 - 0.0085 15.3 0.2 0.009 15.3 0.2 1.1 1 0 0 1 1 1 1 Ion transport protein DUF1357 PF07094.11 CBY08551.1 - 0.018 15.1 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) NCU-G1 PF15065.6 CBY08551.1 - 0.062 12.3 0.1 0.095 11.7 0.1 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Cullin PF00888.22 CBY08553.1 - 3.7e-109 366.1 14.3 4.8e-109 365.7 14.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBY08553.1 - 5.5e-13 48.7 0.3 1.7e-12 47.2 0.1 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain Rx_N PF18052.1 CBY08554.1 - 0.1 12.9 0.8 0.32 11.3 0.1 2.0 2 0 0 2 2 2 0 Rx N-terminal domain ANAPC4_WD40 PF12894.7 CBY08555.1 - 5.2e-05 23.5 0.0 0.24 11.7 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY08555.1 - 0.00052 20.8 8.1 0.037 14.9 0.3 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Ank_2 PF12796.7 CBY08556.1 - 0.07 13.7 0.1 1.4 9.6 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) ZapB PF06005.12 CBY08556.1 - 1.6 9.2 8.6 0.25 11.8 1.4 3.3 2 0 0 2 2 2 0 Cell division protein ZapB Coa1 PF08695.10 CBY08557.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 PIP49_C PF12260.8 CBY08558.1 - 0.00022 20.9 2.7 0.00038 20.1 2.7 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pou PF00157.17 CBY08560.1 - 9.8e-36 121.6 0.1 1.9e-35 120.7 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain PAP_assoc PF03828.19 CBY08562.1 - 7.8e-14 51.6 0.0 2.5e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY08562.1 - 0.00028 21.1 0.0 0.0008 19.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBY08562.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase TFIIF_alpha PF05793.12 CBY08563.1 - 9.8e-46 156.4 50.1 7.2e-42 143.7 44.6 2.3 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 CBY08564.1 - 2e-62 210.9 0.0 3.1e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08564.1 - 1.9e-27 96.2 0.0 6.8e-27 94.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CBY08564.1 - 1.3e-05 24.7 0.4 2.2e-05 23.9 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY08564.1 - 0.0094 15.9 0.2 0.064 13.2 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CBY08564.1 - 1.1 8.9 7.5 4.6 6.8 0.1 3.4 3 1 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 TBCC PF07986.12 CBY08565.1 - 3.2e-21 75.3 1.2 6.9e-21 74.2 1.2 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 CBY08565.1 - 9.3e-06 25.3 1.6 1.8e-05 24.4 1.6 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PMI_typeI PF01238.21 CBY08566.1 - 1e-116 390.2 0.0 1.4e-116 389.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I ER PF01133.17 CBY08567.1 - 4.8e-45 151.6 0.1 5.3e-45 151.4 0.1 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Mce4_CUP1 PF11887.8 CBY08567.1 - 0.07 12.6 0.0 0.093 12.2 0.0 1.1 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative MT-A70 PF05063.14 CBY08568.1 - 2.8e-57 193.4 0.1 4.3e-57 192.8 0.1 1.3 1 0 0 1 1 1 1 MT-A70 zf-C3H1 PF10650.9 CBY08568.1 - 0.00036 20.2 3.8 0.00036 20.2 3.8 2.0 2 0 0 2 2 2 1 Putative zinc-finger domain COLFI PF01410.18 CBY08568.1 - 0.084 12.2 1.0 0.13 11.5 1.0 1.2 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain Lectin_C PF00059.21 CBY08571.1 - 8.2e-13 49.0 7.1 5.2e-09 36.8 0.0 3.0 3 1 0 3 3 3 2 Lectin C-type domain F5_F8_type_C PF00754.25 CBY08571.1 - 0.035 14.2 0.0 0.035 14.2 0.0 2.3 2 1 1 3 3 3 0 F5/8 type C domain EF-hand_6 PF13405.6 CBY08572.1 - 2.2e-10 39.6 0.4 2.3e-06 27.1 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY08572.1 - 4.3e-09 35.3 0.0 3.2e-05 23.2 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY08572.1 - 3.7e-08 33.7 0.0 0.00066 20.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY08572.1 - 9.8e-05 21.7 1.6 0.00016 21.0 0.3 2.0 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CBY08572.1 - 0.038 14.3 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain Lectin_C PF00059.21 CBY08573.1 - 2.8e-14 53.8 0.9 2.8e-14 53.8 0.9 2.3 3 0 0 3 3 3 1 Lectin C-type domain Podoplanin PF05808.11 CBY08573.1 - 0.035 14.2 0.3 0.056 13.5 0.3 1.2 1 0 0 1 1 1 0 Podoplanin Glyco_hydro_18 PF00704.28 CBY08574.1 - 1.5e-57 195.7 3.4 2e-57 195.3 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 CBY08574.1 - 3e-10 40.1 7.3 6.8e-10 39.0 7.3 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Defensin_RK-1 PF17860.1 CBY08574.1 - 0.065 13.7 2.8 0.081 13.4 0.6 2.1 2 0 0 2 2 2 0 RK-1-like defensin Phospholip_A2_1 PF00068.19 CBY08575.1 - 6.4e-15 55.6 5.4 6.4e-15 55.6 5.4 2.1 3 0 0 3 3 3 1 Phospholipase A2 zf-H2C2_2 PF13465.6 CBY08576.1 - 3.9e-18 65.0 7.5 4.6e-08 33.1 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY08576.1 - 7.7e-15 54.4 13.3 1.2e-06 28.6 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY08576.1 - 3.9e-13 49.0 12.7 0.00012 22.6 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY08576.1 - 2.9e-07 30.6 7.9 0.052 13.9 0.3 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY08576.1 - 5.1e-05 23.5 8.8 0.38 11.1 0.0 3.3 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY08576.1 - 0.00011 22.4 4.5 0.088 13.1 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CBY08576.1 - 0.00089 19.1 7.4 0.21 11.6 0.2 3.5 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 CBY08576.1 - 0.0012 19.1 6.5 0.58 10.5 3.1 2.7 1 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 CBY08576.1 - 0.0021 17.8 4.0 0.077 12.9 0.0 3.3 3 0 0 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 CBY08576.1 - 0.01 15.8 16.6 1.3 9.1 3.2 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger ADK_lid PF05191.14 CBY08576.1 - 0.011 15.7 2.3 0.31 11.1 0.6 2.5 2 1 0 2 2 2 0 Adenylate kinase, active site lid Zn-C2H2_12 PF18112.1 CBY08576.1 - 0.013 16.0 2.7 0.97 10.0 0.6 3.1 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2180 PF09947.9 CBY08576.1 - 0.018 15.0 2.7 0.16 11.9 0.8 2.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf_UBZ PF18439.1 CBY08576.1 - 0.045 13.3 8.1 5.6 6.7 0.4 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 CBY08576.1 - 0.06 13.4 6.9 0.11 12.6 3.4 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 CBY08576.1 - 0.062 13.2 2.4 1.2 9.1 1.8 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2HE PF16278.5 CBY08576.1 - 0.077 13.5 11.6 2.7 8.5 0.1 3.5 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CHCC PF10276.9 CBY08576.1 - 0.093 12.8 0.7 56 3.9 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger domain Zn-ribbon_8 PF09723.10 CBY08576.1 - 0.11 12.7 10.9 0.52 10.5 2.0 3.3 1 1 3 4 4 4 0 Zinc ribbon domain RasGAP_C PF03836.15 CBY08576.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Rad50_zn_hook PF04423.14 CBY08576.1 - 0.14 12.0 1.6 5.6 6.9 0.2 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif C1_2 PF03107.16 CBY08576.1 - 0.21 11.9 9.4 8.3 6.8 1.6 3.5 1 1 2 3 3 3 0 C1 domain zf-AN1 PF01428.16 CBY08576.1 - 0.26 11.5 6.7 5.2 7.3 0.1 3.6 4 0 0 4 4 3 0 AN1-like Zinc finger Prok-RING_1 PF14446.6 CBY08576.1 - 0.3 11.1 8.2 7.5 6.6 0.0 3.7 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 ARS2 PF04959.13 CBY08576.1 - 0.35 11.2 2.1 4.4 7.6 0.2 2.2 2 0 0 2 2 2 0 Arsenite-resistance protein 2 YhfH PF14149.6 CBY08576.1 - 0.36 10.9 5.4 16 5.6 0.3 3.4 3 0 0 3 3 3 0 YhfH-like protein HypA PF01155.19 CBY08576.1 - 0.54 10.3 5.8 7.4 6.6 5.6 2.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CBY08576.1 - 0.61 10.2 7.4 7.1 6.7 7.7 2.5 1 1 1 2 2 2 0 Double zinc ribbon DUF2256 PF10013.9 CBY08576.1 - 0.89 9.7 9.4 9 6.5 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 CBY08576.1 - 1.1 9.1 7.8 0.76 9.6 0.3 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 CBY08576.1 - 1.1 9.3 5.7 22 5.1 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-LYAR PF08790.11 CBY08576.1 - 2.1 8.3 7.1 23 5.0 0.3 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DUF1178 PF06676.11 CBY08576.1 - 2.6 8.4 5.8 10 6.5 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) LIM PF00412.22 CBY08576.1 - 7.3 6.9 9.2 4.4 7.6 1.0 3.0 2 1 0 2 2 2 0 LIM domain Prim_Zn_Ribbon PF08273.12 CBY08576.1 - 7.6 6.9 7.6 4.7 7.6 0.5 3.0 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase TFIIS_C PF01096.18 CBY08576.1 - 9.9 6.1 8.1 9.2 6.2 0.1 3.3 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) EGF_CA PF07645.15 CBY08577.1 - 4.6e-126 410.8 291.4 7.6e-11 42.0 11.1 16.4 15 1 1 16 16 16 15 Calcium-binding EGF domain EGF_3 PF12947.7 CBY08577.1 - 2.9e-102 334.6 281.6 8.3e-10 38.7 9.9 16.5 15 1 1 16 16 16 16 EGF domain cEGF PF12662.7 CBY08577.1 - 6.1e-63 208.3 161.3 2.7e-06 27.2 2.0 17.7 16 1 0 16 16 16 14 Complement Clr-like EGF-like EGF PF00008.27 CBY08577.1 - 2.8e-47 158.6 216.5 2e-05 24.8 3.1 17.4 15 2 1 16 16 16 15 EGF-like domain EGF_MSP1_1 PF12946.7 CBY08577.1 - 1.2e-22 79.7 221.7 5e-05 23.3 6.0 16.6 15 1 0 16 16 16 13 MSP1 EGF domain 1 hEGF PF12661.7 CBY08577.1 - 3.7e-17 62.3 218.9 0.00017 22.1 3.8 20.5 22 0 0 22 22 22 14 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY08577.1 - 5.2e-11 42.6 224.4 0.098 13.0 9.0 16.4 12 4 3 15 15 15 12 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY08577.1 - 0.0077 16.5 6.0 0.0077 16.5 6.0 16.7 14 3 2 16 16 16 9 Pvs28 EGF domain TRAP_alpha PF03896.16 CBY08577.1 - 1.4 8.1 3.5 2.8 7.1 3.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit EF-hand_1 PF00036.32 CBY08578.1 - 2.3e-14 51.8 4.2 3.7e-07 29.2 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY08578.1 - 6.4e-12 45.7 0.8 6.2e-06 26.6 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY08578.1 - 2.4e-10 40.1 6.7 1.1e-06 28.3 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY08578.1 - 5.4e-10 38.4 0.2 0.0001 21.9 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY08578.1 - 1.5e-06 27.5 5.7 0.01 15.3 0.3 2.8 2 1 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 CBY08578.1 - 0.00022 21.1 1.5 0.015 15.2 0.1 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBY08578.1 - 0.015 16.1 0.1 0.075 13.9 0.1 2.0 1 1 1 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 CBY08578.1 - 0.052 13.9 0.2 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain DUF900 PF05990.12 CBY08578.1 - 0.071 12.6 0.1 0.089 12.3 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) UPF0154 PF03672.13 CBY08578.1 - 0.15 12.1 0.0 5.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Antimicrobial19 PF08225.11 CBY08578.1 - 0.22 11.2 1.3 7.8 6.2 0.5 2.4 2 0 0 2 2 2 0 Pseudin antimicrobial peptide DED PF01335.21 CBY08578.1 - 0.23 11.8 3.0 22 5.4 0.0 3.0 4 0 0 4 4 4 0 Death effector domain FSA_C PF10479.9 CBY08579.1 - 0.67 8.0 23.8 0.92 7.6 23.8 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus EST1_DNA_bind PF10373.9 CBY08579.1 - 8.4 5.8 7.0 12 5.3 7.0 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Glyco_transf_54 PF04666.13 CBY08580.1 - 1.3e-46 158.8 0.9 1.7e-46 158.4 0.9 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Kelch_1 PF01344.25 CBY08582.1 - 2.3e-26 91.1 0.3 1.4e-09 37.4 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CBY08582.1 - 8.2e-20 70.6 5.3 0.001 19.0 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY08582.1 - 2.8e-18 65.5 3.8 0.00073 19.7 0.0 5.5 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CBY08582.1 - 5.6e-17 61.0 1.0 9.9e-06 25.3 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 CBY08582.1 - 4.4e-12 46.0 0.2 0.0035 17.6 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY08582.1 - 2.5e-11 43.3 3.4 0.00021 21.2 0.0 5.4 6 0 0 6 6 6 4 Kelch motif RRM_1 PF00076.22 CBY08583.1 - 2.4e-11 43.3 0.0 1.1e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arfaptin PF06456.13 CBY08583.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain Mad3_BUB1_I PF08311.12 CBY08584.1 - 0.014 15.4 4.8 1.2 9.1 2.9 3.0 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 Activator-TraM PF11657.8 CBY08584.1 - 1.3 8.8 7.9 1.8 8.4 6.4 2.1 1 1 1 2 2 2 0 Transcriptional activator TraM Fib_alpha PF08702.10 CBY08584.1 - 6.2 7.0 7.4 35 4.6 4.6 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Trypsin PF00089.26 CBY08585.1 - 1.5e-44 152.5 0.7 1.5e-44 152.5 0.7 2.0 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 CBY08585.1 - 0.19 12.2 0.2 0.37 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Mucin PF01456.17 CBY08585.1 - 0.89 9.5 19.2 1.9 8.4 19.2 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Crisp PF08562.10 CBY08585.1 - 6.1 7.5 12.6 0.24 12.0 2.1 3.1 2 1 0 2 2 2 0 Crisp MFS_1 PF07690.16 CBY08586.1 - 3.6e-24 85.3 41.7 7.1e-24 84.4 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY08586.1 - 0.95 8.2 31.7 0.31 9.9 11.2 3.0 2 1 1 3 3 3 0 Sugar (and other) transporter UL41A PF17591.2 CBY08586.1 - 3.6 7.8 5.3 0.62 10.2 0.5 2.3 2 0 0 2 2 2 0 Herpesvirus UL41A DUF3514 PF12027.8 CBY08587.1 - 0.019 14.7 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3514) DUF3847 PF12958.7 CBY08587.1 - 1.7 8.8 4.0 69 3.7 0.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) Sulfotransfer_1 PF00685.27 CBY08588.1 - 6.5e-33 114.3 0.9 9.5e-33 113.8 0.9 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY08588.1 - 3e-05 24.5 0.1 0.024 15.0 0.2 2.9 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_4 PF17784.1 CBY08588.1 - 0.051 13.4 0.0 0.095 12.5 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase domain UPF1_Zn_bind PF09416.10 CBY08589.1 - 6e-69 230.8 2.4 1e-68 230.1 1.5 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) DUF5599 PF18141.1 CBY08589.1 - 6.5e-23 80.8 0.0 1.1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_11 PF13086.6 CBY08589.1 - 7.2e-21 75.1 0.3 1.5e-20 74.1 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBY08589.1 - 1.3e-09 38.1 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY08589.1 - 9.2e-09 35.8 0.1 3e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CBY08589.1 - 3.8e-06 27.0 0.0 7.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CBY08589.1 - 0.00073 18.9 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 CBY08589.1 - 0.0008 19.3 0.1 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 Helicase DEAD PF00270.29 CBY08589.1 - 0.001 18.8 0.2 0.0019 18.0 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 CBY08589.1 - 0.0016 18.1 1.0 0.0022 17.6 0.1 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 CBY08589.1 - 0.003 17.1 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein ATPase PF06745.13 CBY08589.1 - 0.05 13.0 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC SRP54 PF00448.22 CBY08589.1 - 0.053 13.1 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CBY08589.1 - 0.11 12.8 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CBY08590.1 - 6.1e-116 386.6 0.3 6.1e-116 386.6 0.3 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CBY08590.1 - 1.2e-07 31.8 0.7 5.8e-07 29.6 0.0 2.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY08590.1 - 0.00017 21.6 6.1 0.0009 19.2 0.1 2.8 3 0 0 3 3 3 1 RsgA GTPase Coiled-coil_56 PF09813.9 CBY08590.1 - 0.00022 21.2 7.2 0.1 12.7 7.3 3.0 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 56 AIG1 PF04548.16 CBY08590.1 - 0.00034 20.0 0.0 0.00034 20.0 0.0 2.5 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 CBY08590.1 - 0.011 15.3 0.0 0.033 13.8 0.0 1.8 1 0 0 1 1 1 0 Ras family AAA_22 PF13401.6 CBY08590.1 - 0.015 15.5 0.5 0.054 13.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CBY08590.1 - 0.071 13.5 0.4 1.1 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.23 CBY08590.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.8 3 2 1 4 4 4 0 Dynamin family Roc PF08477.13 CBY08590.1 - 0.24 11.6 1.3 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CBY08590.1 - 1.5 9.3 6.6 0.73 10.3 0.2 2.5 2 1 0 2 2 2 0 ABC transporter Exonuc_VII_L PF02601.15 CBY08590.1 - 2 7.9 13.5 2.7 7.5 13.5 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit GTP_EFTU PF00009.27 CBY08590.1 - 2.1 7.8 12.0 1.3 8.5 0.1 3.5 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF4337 PF14235.6 CBY08590.1 - 4.8 7.3 17.3 7.4 6.7 15.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF87 PF01935.17 CBY08590.1 - 8.2 6.5 12.8 19 5.3 6.4 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain FapA PF03961.13 CBY08590.1 - 8.2 4.9 13.3 0.91 8.1 9.0 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A Atg14 PF10186.9 CBY08590.1 - 9.3 5.2 15.4 15 4.6 15.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phospholip_A2_1 PF00068.19 CBY08591.1 - 1.4e-17 64.2 6.3 3.4e-17 62.9 6.3 1.6 1 0 0 1 1 1 1 Phospholipase A2 EGF_CA PF07645.15 CBY08592.1 - 7.2e-12 45.3 19.5 1.5e-08 34.7 3.5 2.2 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 CBY08592.1 - 0.001 18.9 1.2 0.001 18.9 1.2 2.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY08592.1 - 0.0017 18.5 14.9 0.054 13.7 3.0 2.5 2 1 0 2 2 2 2 EGF domain hEGF PF12661.7 CBY08592.1 - 0.021 15.4 4.1 0.021 15.4 4.1 2.8 3 0 0 3 3 3 0 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY08592.1 - 0.86 9.9 14.6 0.68 10.3 5.4 2.8 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Paramecium_SA PF01508.16 CBY08592.1 - 1.1 9.7 13.0 4 7.9 3.7 2.1 2 0 0 2 2 2 0 Paramecium surface antigen domain EGF PF00008.27 CBY08592.1 - 1.8 9.0 18.1 0.28 11.5 8.1 2.8 2 2 0 2 2 2 0 EGF-like domain Lectin_C PF00059.21 CBY08593.1 - 0.00045 20.9 1.9 0.011 16.4 0.2 3.2 2 1 0 2 2 2 1 Lectin C-type domain EGF_CA PF07645.15 CBY08594.1 - 4.5e-77 254.0 201.5 4.7e-10 39.5 12.4 13.9 13 2 1 14 14 14 12 Calcium-binding EGF domain EGF_3 PF12947.7 CBY08594.1 - 8.5e-70 230.7 198.1 6.1e-09 35.9 10.4 13.3 13 0 0 13 13 13 12 EGF domain cEGF PF12662.7 CBY08594.1 - 7.2e-46 153.7 133.6 3.8e-07 29.9 4.2 15.0 14 0 0 14 14 14 10 Complement Clr-like EGF-like EGF PF00008.27 CBY08594.1 - 2.9e-26 91.4 170.5 4.2e-05 23.7 5.2 13.9 13 0 0 13 13 13 12 EGF-like domain FXa_inhibition PF14670.6 CBY08594.1 - 1e-15 57.7 177.7 0.029 14.6 4.8 13.8 10 2 3 13 13 13 11 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY08594.1 - 3.2e-14 52.7 143.9 0.012 15.7 5.7 13.4 13 0 0 13 13 13 11 MSP1 EGF domain 1 hEGF PF12661.7 CBY08594.1 - 2e-09 37.7 167.7 0.002 18.7 1.7 17.3 18 0 0 18 18 18 10 Human growth factor-like EGF EGF_2 PF07974.13 CBY08594.1 - 0.023 15.1 5.5 0.023 15.1 5.5 14.1 12 1 1 13 13 13 0 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY08594.1 - 0.034 14.5 155.4 0.04 14.2 5.0 12.8 12 1 1 13 13 13 0 Pvs28 EGF domain Zona_pellucida PF00100.23 CBY08595.1 - 1.5e-10 41.4 0.9 1.5e-10 41.3 0.9 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Dicer_dimer PF03368.14 CBY08597.1 - 0.21 11.7 1.3 0.32 11.2 0.1 1.9 2 0 0 2 2 2 0 Dicer dimerisation domain AIRS_C PF02769.22 CBY08598.1 - 2.9e-25 89.2 0.2 3.7e-25 88.9 0.2 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CBY08598.1 - 0.025 15.2 0.0 0.064 13.9 0.0 1.7 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain GRAM PF02893.20 CBY08600.1 - 7.1e-49 164.4 6.8 8.7e-24 83.6 0.7 2.4 2 0 0 2 2 2 2 GRAM domain VASt PF16016.5 CBY08600.1 - 8.3e-26 91.2 0.9 8.3e-26 91.2 0.9 2.2 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain Acp26Ab PF05777.12 CBY08600.1 - 0.062 13.9 1.2 21 5.8 0.1 2.8 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) RNase_T PF00929.24 CBY08601.1 - 1.1e-26 94.3 0.0 1.3e-26 94.1 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Thioredoxin PF00085.20 CBY08602.1 - 1.8e-07 31.1 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin adh_short PF00106.25 CBY08603.1 - 1.7e-23 83.1 0.0 2.9e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY08603.1 - 2.9e-14 53.2 0.0 1.4e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY08603.1 - 0.0011 19.0 0.1 0.02 14.8 0.0 2.2 2 1 0 2 2 2 1 KR domain CD225 PF04505.12 CBY08604.1 - 2.2e-13 50.1 0.5 3.8e-13 49.4 0.5 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein adh_short PF00106.25 CBY08605.1 - 1.7e-23 83.1 0.0 2.9e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY08605.1 - 2.9e-14 53.2 0.0 1.4e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY08605.1 - 0.0011 19.0 0.1 0.02 14.8 0.0 2.2 2 1 0 2 2 2 1 KR domain CD225 PF04505.12 CBY08606.1 - 2.2e-13 50.1 0.5 3.8e-13 49.4 0.5 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein CBM_14 PF01607.24 CBY08607.1 - 3.5e-12 46.3 2.9 3.5e-12 46.3 2.9 1.8 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Glycos_transf_2 PF00535.26 CBY08608.1 - 0.00024 20.9 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ion_trans PF00520.31 CBY08609.1 - 3.5e-17 62.4 16.2 4.4e-17 62.1 16.2 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY08609.1 - 1.5e-12 47.4 0.0 2.3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CBY08609.1 - 0.0035 17.3 2.3 0.0072 16.3 2.3 1.5 1 0 0 1 1 1 1 Ion channel TACC_C PF05010.14 CBY08609.1 - 0.01 15.7 2.5 0.018 14.8 2.5 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Ion_trans_N PF08412.10 CBY08609.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Ion transport protein N-terminal RsgA_GTPase PF03193.16 CBY08610.1 - 6.8e-05 22.8 0.1 0.00023 21.1 0.1 1.9 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 CBY08610.1 - 8.2e-05 23.0 0.2 0.0059 17.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CBY08610.1 - 0.0017 17.6 0.1 0.012 14.8 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CBY08610.1 - 0.0051 17.1 1.3 0.016 15.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CBY08610.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 CBY08610.1 - 0.068 13.6 0.1 0.36 11.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBY08610.1 - 0.23 12.0 0.0 0.23 12.0 0.0 3.6 5 2 0 5 5 5 0 ABC transporter ATPase_2 PF01637.18 CBY08610.1 - 3.1 7.6 9.2 0.11 12.4 0.8 2.9 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Pkinase PF00069.25 CBY08612.1 - 2.9e-55 187.5 0.0 3.3e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08612.1 - 4.8e-26 91.6 0.0 6.5e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY08612.1 - 0.00057 18.9 0.1 0.00091 18.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY08612.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 CBY08612.1 - 0.045 12.5 0.0 0.091 11.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CBY08612.1 - 0.12 12.0 0.4 0.33 10.5 0.4 1.7 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 CBY08613.1 - 1.4e-64 218.0 0.0 1.7e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08613.1 - 2.5e-29 102.4 0.0 3.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY08613.1 - 1.5e-08 34.0 0.0 2.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY08613.1 - 1.6e-05 24.4 0.0 0.0029 17.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CBY08613.1 - 0.024 13.4 0.0 0.049 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase zf-C4 PF00105.18 CBY08614.1 - 1e-27 96.4 20.3 1.7e-27 95.6 20.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY08614.1 - 0.0014 18.2 2.7 0.079 12.5 2.7 2.4 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ELL PF10390.9 CBY08617.1 - 0.083 12.4 0.1 0.09 12.3 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Sa_NUDIX PF18167.1 CBY08618.1 - 0.041 13.7 1.1 0.056 13.2 1.1 1.3 1 1 0 1 1 1 0 SMODS-associated NUDIX domain zf-C4 PF00105.18 CBY08619.1 - 2.3e-35 120.8 37.7 1.2e-23 83.3 19.0 2.6 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY08619.1 - 4.1e-09 36.3 2.9 4.1e-09 36.3 2.9 2.4 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor RST PF12174.8 CBY08619.1 - 0.0011 18.8 0.6 2.5 8.1 0.1 2.8 2 0 0 2 2 2 2 RCD1-SRO-TAF4 (RST) plant domain Cullin_Nedd8 PF10557.9 CBY08619.1 - 0.0038 17.2 1.5 3.7 7.6 0.1 2.8 2 0 0 2 2 2 2 Cullin protein neddylation domain Sigma70_r1_1 PF03979.14 CBY08619.1 - 0.0086 16.1 2.5 3.3 7.8 0.2 2.5 2 0 0 2 2 2 2 Sigma-70 factor, region 1.1 Mesd PF10185.9 CBY08619.1 - 0.011 15.6 1.4 4.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor Vma12 PF11712.8 CBY08619.1 - 0.013 15.5 1.6 4.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4923 PF16270.5 CBY08619.1 - 0.029 14.2 1.8 7.8 6.3 0.1 2.9 3 0 0 3 3 3 0 Lipocalin-like domain (DUF4923) DUF3846 PF12957.7 CBY08619.1 - 0.089 13.1 0.2 42 4.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3846) Calsarcin PF05556.11 CBY08619.1 - 0.87 9.1 4.5 1 8.9 0.6 2.2 1 1 1 2 2 2 0 Calcineurin-binding protein (Calsarcin) ASC PF00858.24 CBY08620.1 - 2.5e-47 161.9 12.2 4.1e-47 161.2 12.2 1.3 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel IL7 PF01415.16 CBY08620.1 - 3.3 7.7 6.5 9.1 6.3 2.2 2.5 2 0 0 2 2 2 0 Interleukin 7/9 family SNF PF00209.18 CBY08622.1 - 5e-41 141.0 2.8 5.7e-41 140.8 2.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family AA_permease_2 PF13520.6 CBY08622.1 - 0.0024 16.8 1.5 0.0028 16.6 1.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CBY08623.1 - 2.6e-56 191.3 30.3 3.5e-56 190.9 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY08623.1 - 3.2e-18 65.6 30.4 3.9e-18 65.3 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease DPM3 PF08285.11 CBY08623.1 - 0.75 10.0 5.4 1.6 9.0 1.5 2.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TRAP_beta PF05753.14 CBY08624.1 - 7.2e-33 113.5 0.2 9.1e-33 113.1 0.2 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) AA_permease_2 PF13520.6 CBY08625.1 - 6.1e-54 183.5 43.0 7.6e-54 183.2 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY08625.1 - 5.3e-16 58.3 41.2 6.2e-16 58.1 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease TRAP_beta PF05753.14 CBY08626.1 - 3.4e-44 150.4 0.3 4.3e-44 150.0 0.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.11 CBY08626.1 - 0.0014 18.9 0.4 0.0021 18.3 0.4 1.3 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.9 CBY08626.1 - 0.0075 16.5 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 NPCBM-associated, NEW3 domain of alpha-galactosidase BatD PF13584.6 CBY08626.1 - 0.011 14.6 0.4 0.018 13.9 0.1 1.6 1 1 0 1 1 1 0 Oxygen tolerance Methyltransf_8 PF05148.15 CBY08627.1 - 2.8e-70 236.6 2.5 2.8e-70 236.6 2.5 1.4 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CBY08627.1 - 3.3e-08 34.0 0.1 2e-07 31.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY08627.1 - 1.6e-07 31.1 0.1 0.0011 18.5 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 CBY08627.1 - 5.8e-07 30.1 0.2 0.00044 20.9 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY08627.1 - 0.00015 21.6 0.0 0.001 18.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBY08627.1 - 0.0056 16.7 0.0 0.0056 16.7 0.0 2.8 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBY08627.1 - 0.016 15.2 0.1 0.016 15.2 0.1 3.0 3 0 0 3 3 3 0 Methyltransferase domain Ubie_methyltran PF01209.18 CBY08627.1 - 0.017 14.4 0.1 0.24 10.7 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family FAM60A PF15396.6 CBY08627.1 - 0.031 14.3 12.8 0.066 13.2 12.8 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Ndc1_Nup PF09531.10 CBY08627.1 - 0.034 12.8 3.3 0.039 12.7 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MetW PF07021.12 CBY08627.1 - 0.095 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 CBY08627.1 - 0.59 10.9 1.9 10 7.0 0.0 3.2 2 2 1 3 3 3 0 Methyltransferase domain AAA PF00004.29 CBY08628.1 - 2.5e-47 160.6 0.0 4.2e-42 143.7 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 CBY08628.1 - 4.6e-21 74.7 0.3 1.4e-20 73.1 0.3 1.9 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 CBY08628.1 - 2.4e-07 30.4 0.0 6.7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBY08628.1 - 3.2e-06 27.4 0.0 3.6e-05 23.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) Tudor-knot PF11717.8 CBY08628.1 - 3.9e-06 26.7 1.3 9e-06 25.5 1.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain IstB_IS21 PF01695.17 CBY08628.1 - 3.7e-05 23.5 0.0 8.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CBY08628.1 - 5.3e-05 23.7 0.2 0.00054 20.4 0.0 2.7 2 1 0 2 2 1 1 AAA ATPase domain PBP1_TM PF14812.6 CBY08628.1 - 0.0013 19.0 10.4 0.0013 19.0 10.4 3.6 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_helicase PF00910.22 CBY08628.1 - 0.002 18.5 0.0 0.0076 16.6 0.0 2.1 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.17 CBY08628.1 - 0.0022 17.1 0.0 0.083 12.0 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 CBY08628.1 - 0.0024 17.9 0.0 0.012 15.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBY08628.1 - 0.0032 17.2 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBY08628.1 - 0.0038 16.5 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CBY08628.1 - 0.0068 16.7 1.7 0.15 12.3 0.1 3.7 4 1 0 4 4 3 1 AAA domain Sigma54_activ_2 PF14532.6 CBY08628.1 - 0.0078 16.3 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 CBY08628.1 - 0.0097 16.5 0.0 0.083 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CBY08628.1 - 0.012 15.6 0.4 0.087 12.8 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CBY08628.1 - 0.022 14.3 0.0 0.077 12.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CBY08628.1 - 0.024 14.8 0.4 0.22 11.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBY08628.1 - 0.039 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CBY08628.1 - 0.043 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CBY08628.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CBY08628.1 - 1.2 8.8 0.0 1.2 8.8 0.0 3.6 3 1 0 3 3 2 0 AAA domain CN_hydrolase PF00795.22 CBY08630.1 - 6e-62 209.3 0.0 6.7e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Thioredoxin PF00085.20 CBY08631.1 - 3.7e-24 84.7 0.0 8.7e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CBY08631.1 - 5.4e-10 39.5 0.0 6.2e-05 23.0 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY08631.1 - 0.0058 17.1 0.0 0.1 13.1 0.0 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Nop53 PF07767.11 CBY08631.1 - 0.65 9.3 4.5 0.9 8.9 4.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MFS_1 PF07690.16 CBY08632.1 - 2.4e-07 30.0 29.9 2.4e-07 30.0 29.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily YrzO PF14142.6 CBY08633.1 - 0.25 11.3 1.2 0.64 10.0 1.2 1.7 1 0 0 1 1 1 0 YrzO-like protein TFIIA PF03153.13 CBY08633.1 - 0.92 9.4 16.5 1.1 9.1 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMC PF07810.13 CBY08634.1 - 2.7e-32 111.6 1.0 2.7e-32 111.6 1.0 3.3 5 0 0 5 5 5 1 TMC domain DUF4330 PF14221.6 CBY08634.1 - 8.6 6.5 6.7 17 5.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4330) Lectin_C PF00059.21 CBY08635.1 - 1.9e-15 57.5 22.3 3.1e-05 24.6 1.5 4.6 4 0 0 4 4 4 4 Lectin C-type domain Claudin_2 PF13903.6 CBY08637.1 - 0.18 11.6 7.3 0.28 10.9 7.3 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.6 CBY08637.1 - 1.6 9.1 9.5 1.9 8.8 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) MyTH4 PF00784.17 CBY08638.1 - 1.3e-13 51.3 0.4 1.3e-13 51.3 0.4 2.3 3 0 0 3 3 3 1 MyTH4 domain FERM_N PF09379.10 CBY08638.1 - 2.8e-06 27.2 0.0 9.1e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 CBY08638.1 - 0.00017 22.0 0.1 0.00058 20.2 0.0 1.8 2 0 0 2 2 2 1 FERM central domain BAG PF02179.16 CBY08638.1 - 0.017 15.5 1.1 0.24 11.9 0.2 2.5 2 0 0 2 2 2 0 BAG domain EGF PF00008.27 CBY08639.1 - 7.5e-106 345.8 429.0 1.6e-06 28.3 6.0 27.6 28 0 0 28 28 28 26 EGF-like domain hEGF PF12661.7 CBY08639.1 - 4.2e-50 166.8 334.2 0.003 18.1 1.3 29.0 26 0 0 26 26 26 25 Human growth factor-like EGF EGF_2 PF07974.13 CBY08639.1 - 8.2e-33 112.5 459.0 0.00023 21.4 3.5 26.5 25 1 1 26 26 26 22 EGF-like domain EGF_3 PF12947.7 CBY08639.1 - 1.8e-10 40.8 398.0 0.0069 16.6 10.1 27.3 25 3 3 28 28 28 20 EGF domain EGF_CA PF07645.15 CBY08639.1 - 0.0021 18.2 9.8 0.0021 18.2 9.8 26.9 5 4 22 27 27 27 8 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 CBY08639.1 - 0.014 15.7 6.1 0.014 15.7 6.1 27.3 14 8 11 25 25 25 0 Pvs28 EGF domain O-FucT PF10250.9 CBY08641.1 - 1.8e-08 34.5 0.8 2.2e-08 34.2 0.8 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF1768 PF08719.11 CBY08641.1 - 0.055 13.7 0.5 0.55 10.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1768) Adap_comp_sub PF00928.21 CBY08642.1 - 6.7e-57 192.8 0.3 1.7e-27 96.5 0.0 2.2 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBY08642.1 - 4.3e-05 23.5 0.2 8.8e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TRIF-NTD PF17798.1 CBY08642.1 - 0.0032 17.6 0.4 3.7 7.6 0.0 2.5 2 0 0 2 2 2 2 TRIF N-terminal domain DUF503 PF04456.12 CBY08642.1 - 0.033 14.0 8.4 2.4 8.1 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF503) PBP5_C PF07943.13 CBY08642.1 - 0.062 13.5 1.0 26 5.1 0.0 3.3 2 1 1 3 3 3 0 Penicillin-binding protein 5, C-terminal domain RPM2 PF08579.11 CBY08642.1 - 0.087 13.2 0.3 0.17 12.3 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) GRP PF07172.11 CBY08642.1 - 3.8 8.3 18.4 0.17 12.6 7.4 2.5 2 0 0 2 2 2 0 Glycine rich protein family DUF1104 PF06518.11 CBY08643.1 - 0.12 12.7 3.2 0.37 11.2 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) DnaJ PF00226.31 CBY08644.1 - 4.3e-20 71.6 2.1 4.3e-20 71.6 2.1 1.8 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.6 CBY08644.1 - 0.051 13.5 0.1 0.23 11.4 0.0 2.2 2 1 1 3 3 3 0 A repeated domain in UCH-protein baeRF_family5 PF18846.1 CBY08644.1 - 2.3 8.4 7.2 0.23 11.7 2.6 1.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 Dimerisation PF08100.11 CBY08645.1 - 0.018 15.0 0.1 0.5 10.4 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain Y_phosphatase PF00102.27 CBY08646.1 - 4.6e-181 599.1 0.0 5.1e-73 245.5 0.0 3.3 3 0 0 3 3 3 3 Protein-tyrosine phosphatase fn3 PF00041.21 CBY08646.1 - 1.2e-21 76.8 2.5 4.6e-08 33.3 0.0 5.6 6 0 0 6 6 5 3 Fibronectin type III domain MAM PF00629.23 CBY08646.1 - 4.3e-20 72.2 1.0 1.1e-19 70.9 1.0 1.8 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DSPc PF00782.20 CBY08646.1 - 4.3e-15 55.7 0.0 0.00022 21.0 0.0 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Ig_3 PF13927.6 CBY08646.1 - 1.2e-06 29.0 0.1 0.051 14.2 0.0 4.4 4 0 0 4 4 3 1 Immunoglobulin domain Ig_2 PF13895.6 CBY08646.1 - 0.00027 21.2 0.0 0.016 15.6 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin domain Y_phosphatase3 PF13350.6 CBY08646.1 - 0.00076 19.5 0.0 0.35 10.8 0.0 3.1 3 0 0 3 3 3 1 Tyrosine phosphatase family I-set PF07679.16 CBY08646.1 - 0.00081 19.4 0.0 0.0029 17.7 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain CarboxypepD_reg PF13620.6 CBY08646.1 - 0.0015 18.8 1.1 0.15 12.4 0.1 3.2 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain AbiEi_3 PF11459.8 CBY08646.1 - 0.0074 16.0 0.0 6.1 6.5 0.0 2.6 2 0 0 2 2 2 2 Transcriptional regulator, AbiEi antitoxin, Type IV TA system PTPlike_phytase PF14566.6 CBY08646.1 - 0.02 15.0 0.0 7 6.8 0.0 3.4 3 0 0 3 3 3 0 Inositol hexakisphosphate DUF2989 PF11207.8 CBY08646.1 - 0.022 14.5 0.2 8.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) Kelch_6 PF13964.6 CBY08647.1 - 0.0055 16.9 2.2 1.5 9.2 0.0 3.3 4 0 0 4 4 4 2 Kelch motif VWA PF00092.28 CBY08648.1 - 5e-28 98.5 0.2 1.7e-27 96.8 0.2 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY08648.1 - 3.8e-12 46.8 0.0 1.4e-11 45.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain FeS_assembly_P PF01883.19 CBY08648.1 - 0.0058 16.8 0.0 4.2 7.6 0.0 2.6 2 0 0 2 2 2 2 Iron-sulfur cluster assembly protein EMP24_GP25L PF01105.24 CBY08648.1 - 0.023 14.6 0.2 0.051 13.5 0.2 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD EB PF01683.18 CBY08648.1 - 0.13 12.6 14.5 0.35 11.2 3.1 2.8 2 0 0 2 2 2 0 EB module EGF PF00008.27 CBY08648.1 - 0.84 10.0 14.3 1.1 9.7 1.8 2.9 2 0 0 2 2 2 0 EGF-like domain cEGF PF12662.7 CBY08648.1 - 7.3 6.6 7.9 6.5 6.8 1.6 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like Prefoldin PF02996.17 CBY08649.1 - 2.2e-15 56.6 0.2 3.5e-15 56.0 0.2 1.3 1 1 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.12 CBY08649.1 - 0.091 12.8 2.0 7.7 6.6 0.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-RING_2 PF13639.6 CBY08650.1 - 3e-10 40.2 8.0 6.2e-10 39.3 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY08650.1 - 2e-08 34.0 6.7 4.9e-08 32.7 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY08650.1 - 4.7e-07 29.8 1.3 1e-06 28.7 1.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CBY08650.1 - 5.3e-07 29.6 3.9 6.8e-07 29.2 2.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY08650.1 - 1e-06 28.5 8.6 1e-06 28.5 8.6 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY08650.1 - 1.8e-06 28.2 6.4 4.8e-06 26.8 6.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY08650.1 - 4.2e-06 26.6 8.7 4.2e-06 26.6 8.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 CBY08650.1 - 7.6e-06 25.6 7.2 1.5e-05 24.7 7.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CBY08650.1 - 1.4e-05 25.2 3.0 1.4e-05 25.2 3.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBY08650.1 - 0.00011 21.9 7.4 0.00011 21.9 7.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY08650.1 - 0.0012 18.6 9.5 0.0038 17.1 9.6 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBY08650.1 - 0.0036 17.1 1.5 0.0095 15.8 1.5 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein WD40_alt PF14077.6 CBY08650.1 - 0.011 15.5 0.3 0.053 13.4 0.3 2.2 1 0 0 1 1 1 0 Alternative WD40 repeat motif Zn_ribbon_17 PF17120.5 CBY08650.1 - 0.016 14.8 6.4 0.037 13.7 6.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type GAS PF13851.6 CBY08650.1 - 0.033 13.5 31.4 0.33 10.3 5.0 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FYVE PF01363.21 CBY08650.1 - 0.23 11.6 9.3 0.82 9.8 9.3 2.0 1 1 0 1 1 1 0 FYVE zinc finger DASH_Dam1 PF08653.10 CBY08650.1 - 0.45 10.3 2.7 11 5.9 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 bZIP_1 PF00170.21 CBY08650.1 - 0.88 9.7 26.2 1.9 8.6 0.2 5.4 4 1 1 5 5 5 0 bZIP transcription factor DZR PF12773.7 CBY08650.1 - 1.2 9.2 8.1 6.4 6.9 8.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon IBR PF01485.21 CBY08650.1 - 1.3 9.3 10.8 5.9 7.2 8.5 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FlaC_arch PF05377.11 CBY08650.1 - 1.3 9.4 17.5 3.5 8.1 0.5 5.2 3 1 3 6 6 6 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CBY08650.1 - 1.9 8.3 24.2 5.2 6.9 0.2 5.0 2 1 3 5 5 5 0 Septum formation initiator bZIP_2 PF07716.15 CBY08650.1 - 1.9 8.6 19.8 3.7 7.7 1.5 5.2 3 1 2 5 5 5 0 Basic region leucine zipper ZapB PF06005.12 CBY08650.1 - 3.7 8.1 28.7 6.8 7.2 0.2 5.1 2 1 1 4 4 4 0 Cell division protein ZapB LMBR1 PF04791.16 CBY08650.1 - 9.6 5.0 11.8 13 4.5 11.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Vitellogenin_N PF01347.22 CBY08651.1 - 0.1 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Glycos_transf_2 PF00535.26 CBY08652.1 - 0.00081 19.2 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DivIC PF04977.15 CBY08653.1 - 0.059 13.2 31.1 0.11 12.3 0.4 5.3 3 1 2 5 5 5 0 Septum formation initiator SnoaL PF07366.12 CBY08653.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase ADIP PF11559.8 CBY08653.1 - 0.35 10.9 32.5 0.052 13.6 6.5 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 CBY08653.1 - 0.52 11.0 13.4 2.6 8.7 0.2 4.4 3 1 1 4 4 4 0 SlyX bZIP_2 PF07716.15 CBY08653.1 - 1 9.5 27.4 1.6 8.9 1.2 5.1 3 1 2 5 5 5 0 Basic region leucine zipper bZIP_1 PF00170.21 CBY08653.1 - 4.4 7.5 31.0 4.1 7.6 2.2 5.0 4 1 0 4 4 4 0 bZIP transcription factor Strep_SA_rep PF06696.11 CBY08653.1 - 5.5 7.1 6.4 31 4.7 1.2 3.2 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Pterin_4a PF01329.19 CBY08654.1 - 3.2e-28 97.7 0.0 3.8e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase zf-RING_2 PF13639.6 CBY08655.1 - 1.6e-07 31.6 5.6 2.9e-07 30.7 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY08655.1 - 3.1e-05 23.7 5.5 7.3e-05 22.6 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY08655.1 - 4.9e-05 23.3 4.7 0.00012 22.0 4.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY08655.1 - 0.00032 20.5 5.0 0.00064 19.5 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY08655.1 - 0.00072 19.5 6.5 0.0014 18.5 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBY08655.1 - 0.00073 19.8 4.8 0.0019 18.4 4.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBY08655.1 - 0.00082 19.2 5.6 0.0019 18.0 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY08655.1 - 0.0021 18.1 0.7 0.0021 18.1 0.7 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CBY08655.1 - 0.01 15.9 0.6 0.024 14.7 0.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger WD40_alt PF14077.6 CBY08655.1 - 0.055 13.3 0.2 0.055 13.3 0.2 2.9 3 0 0 3 3 3 0 Alternative WD40 repeat motif IBR PF01485.21 CBY08655.1 - 0.11 12.7 6.0 0.31 11.3 6.0 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn_ribbon_17 PF17120.5 CBY08655.1 - 0.19 11.4 4.7 0.34 10.6 4.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CBY08655.1 - 0.2 11.5 4.2 0.39 10.5 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CBY08655.1 - 0.21 11.5 1.1 0.45 10.4 1.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Leuk-A4-hydro_C PF09127.11 CBY08655.1 - 0.28 11.3 6.9 1.2 9.2 0.2 4.0 4 1 1 5 5 5 0 Leukotriene A4 hydrolase, C-terminal Prok-RING_4 PF14447.6 CBY08655.1 - 0.41 10.6 4.8 0.95 9.4 4.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 C1_1 PF00130.22 CBY08655.1 - 2.6 8.0 8.3 9 6.3 0.7 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAS PF13851.6 CBY08655.1 - 4.5 6.6 42.7 0.2 11.0 12.0 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 CBY08655.1 - 4.9 7.3 25.0 2.9 8.0 1.3 5.6 4 2 1 5 5 5 0 Basic region leucine zipper HHH_4 PF14490.6 CBY08656.1 - 0.074 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain zf-RING_2 PF13639.6 CBY08657.1 - 1.1e-09 38.5 9.1 2.1e-09 37.6 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY08657.1 - 4.4e-07 29.6 6.9 9.6e-07 28.6 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY08657.1 - 1.2e-06 28.4 2.0 3e-06 27.2 2.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CBY08657.1 - 3.4e-06 26.8 10.2 7.5e-06 25.7 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY08657.1 - 8.6e-06 25.7 8.2 2.7e-05 24.1 8.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY08657.1 - 9.3e-06 25.8 7.6 2.5e-05 24.5 7.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY08657.1 - 1.2e-05 25.2 8.2 1.2e-05 25.2 8.2 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 CBY08657.1 - 3e-05 23.7 6.8 5.7e-05 22.8 6.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CBY08657.1 - 5.5e-05 23.2 4.9 5.5e-05 23.2 4.9 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBY08657.1 - 0.00026 20.7 8.7 0.00063 19.5 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY08657.1 - 0.00048 19.9 7.0 0.0011 18.8 7.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBY08657.1 - 0.089 12.7 4.5 0.044 13.6 1.6 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 CBY08657.1 - 0.11 12.2 7.9 0.2 11.3 7.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type WD40_alt PF14077.6 CBY08657.1 - 0.13 12.1 0.3 0.13 12.1 0.3 2.7 3 0 0 3 3 2 0 Alternative WD40 repeat motif zf-RING_10 PF16685.5 CBY08657.1 - 0.54 10.4 6.0 2 8.6 6.0 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 CBY08657.1 - 1.2 9.4 9.2 4.7 7.4 9.2 2.0 1 1 0 1 1 1 0 FYVE zinc finger DUF1272 PF06906.11 CBY08657.1 - 1.8 8.8 5.5 4.7 7.4 5.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 CBY08657.1 - 2.2 8.4 8.0 10 6.3 8.0 2.0 1 1 1 2 2 2 0 Double zinc ribbon MRPL52 PF18699.1 CBY08657.1 - 2.7 8.3 20.5 1.8 8.8 5.6 3.5 2 1 1 3 3 3 0 Mitoribosomal protein mL52 ADIP PF11559.8 CBY08657.1 - 4.1 7.5 39.9 5.1 7.2 4.7 3.7 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding IBR PF01485.21 CBY08657.1 - 5.3 7.4 11.5 18 5.6 9.0 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF2656 PF10847.8 CBY08658.1 - 0.025 14.7 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) EzrA PF06160.12 CBY08658.1 - 0.047 11.9 2.5 0.053 11.7 2.5 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA PHM7_cyt PF14703.6 CBY08659.1 - 0.01 16.1 1.2 0.68 10.2 0.1 2.5 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 CBY08659.1 - 0.038 13.8 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_3 PF13469.6 CBY08660.1 - 5.9e-06 26.8 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY08660.1 - 9.8e-05 22.0 0.3 0.00025 20.6 0.3 1.6 1 0 0 1 1 1 1 Sulfotransferase domain EF-hand_6 PF13405.6 CBY08662.1 - 9.2e-06 25.2 1.6 0.019 14.9 0.3 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBY08662.1 - 0.004 16.6 1.2 0.048 13.2 0.2 3.0 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 CBY08662.1 - 0.0042 17.5 2.6 0.024 15.1 2.6 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY08662.1 - 0.054 13.3 2.6 11 6.0 0.2 3.7 4 0 0 4 4 4 0 EF-hand domain pair DUF2046 PF09755.9 CBY08662.1 - 0.095 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Catalase-rel PF06628.12 CBY08662.1 - 0.11 12.7 0.1 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Catalase-related immune-responsive Kelch_6 PF13964.6 CBY08663.1 - 8.1e-26 89.4 3.1 4.4e-05 23.6 0.0 5.9 4 1 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CBY08663.1 - 1.7e-24 85.1 2.8 8.1e-07 28.5 0.0 5.4 5 0 0 5 5 5 5 Kelch motif BACK PF07707.15 CBY08663.1 - 2.1e-20 72.7 1.1 5.1e-20 71.5 1.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CBY08663.1 - 2.1e-19 69.1 8.5 1.9e-05 24.5 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 CBY08663.1 - 7.6e-16 57.8 2.9 1.3e-07 31.5 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY08663.1 - 7.6e-11 42.0 0.2 0.045 14.1 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY08663.1 - 1e-09 38.0 3.3 0.13 12.2 0.0 5.0 4 1 0 4 4 4 3 Kelch motif SANTA PF09133.10 CBY08663.1 - 0.0017 18.8 0.9 0.12 12.9 0.0 3.6 2 1 1 3 3 3 1 SANTA (SANT Associated) BTB PF00651.31 CBY08663.1 - 0.0091 16.2 0.9 0.097 12.9 0.1 2.8 1 1 1 2 2 2 1 BTB/POZ domain PPP1R32 PF15691.5 CBY08664.1 - 0.01 15.0 0.0 0.011 14.9 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 32 Mub_B2 PF17966.1 CBY08664.1 - 0.046 14.4 0.3 0.064 14.0 0.3 1.3 1 0 0 1 1 1 0 Mub B2-like domain Tube PF17212.3 CBY08665.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.3 1 1 0 1 1 1 0 Tail tubular protein TSP_1 PF00090.19 CBY08666.1 - 0.0017 18.5 3.2 0.0017 18.5 3.2 4.3 3 1 0 3 3 3 2 Thrombospondin type 1 domain TSP_1 PF00090.19 CBY08667.1 - 3.4e-07 30.4 4.6 8e-07 29.2 4.6 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain DUF3899 PF13038.6 CBY08667.1 - 0.012 16.1 1.9 1.9 9.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Ig_3 PF13927.6 CBY08667.1 - 0.015 15.9 0.0 0.58 10.8 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain DUF3909 PF13077.6 CBY08668.1 - 0.027 14.6 0.5 0.052 13.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) DUF3502 PF12010.8 CBY08668.1 - 0.062 13.9 2.5 2.4 8.8 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3502) Telomere_Sde2_2 PF13297.6 CBY08670.1 - 3e-19 68.4 0.3 8.3e-19 67.0 0.1 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 CBY08670.1 - 5.4e-19 68.6 1.4 5.4e-19 68.6 1.4 2.4 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Miga PF10265.9 CBY08672.1 - 1.3e-60 205.9 5.0 8.7e-60 203.2 5.0 1.9 1 1 0 1 1 1 1 Mitoguardin Lipocalin_7 PF14651.6 CBY08674.1 - 1.3e-13 51.0 0.4 1.4e-13 50.8 0.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF1521 PF07481.11 CBY08674.1 - 0.029 14.4 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) EGF_3 PF12947.7 CBY08675.1 - 7.9e-50 166.8 344.7 5.1e-08 33.0 8.2 22.1 19 2 2 21 21 21 14 EGF domain EGF_CA PF07645.15 CBY08675.1 - 1.4e-19 70.0 93.8 6.3e-09 35.9 9.1 22.1 16 4 6 22 22 22 8 Calcium-binding EGF domain EGF PF00008.27 CBY08675.1 - 3.3e-13 49.7 320.1 0.0005 20.3 10.0 23.3 20 2 1 22 22 22 13 EGF-like domain hEGF PF12661.7 CBY08675.1 - 8e-05 23.1 15.6 0.00047 20.7 3.7 25.8 22 1 0 22 22 22 9 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY08675.1 - 0.0016 18.5 11.4 0.0016 18.5 11.4 20.5 20 1 1 21 21 21 12 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY08675.1 - 0.0093 16.3 1.3 0.0093 16.3 1.3 21.8 21 1 1 22 22 22 9 Pvs28 EGF domain cEGF PF12662.7 CBY08675.1 - 0.043 13.8 211.1 0.077 12.9 6.1 22.6 21 2 0 21 21 21 0 Complement Clr-like EGF-like DUF3288 PF11691.8 CBY08675.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) Dickkopf_N PF04706.12 CBY08676.1 - 2.1e-12 47.3 40.6 6.8e-12 45.7 20.2 3.4 3 0 0 3 3 3 2 Dickkopf N-terminal cysteine-rich region UPF0506 PF11703.8 CBY08676.1 - 10 6.6 37.6 0.076 13.4 17.9 3.6 4 0 0 4 4 4 0 UPF0506 Ig_3 PF13927.6 CBY08677.1 - 2.3e-15 57.0 1.3 1.7e-11 44.5 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CBY08677.1 - 1.4e-12 47.8 0.2 7.5e-07 29.4 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY08677.1 - 2e-09 37.4 0.4 2.8e-06 27.3 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin I-set domain ig PF00047.25 CBY08677.1 - 2.7e-09 37.1 0.1 4.7e-06 26.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 CBY08677.1 - 4.5e-05 23.1 0.2 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 Adenovirus E3 region protein CR1 V-set PF07686.17 CBY08677.1 - 0.00018 21.6 0.9 0.032 14.4 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain Podoplanin PF05808.11 CBY08677.1 - 0.0084 16.2 0.8 0.013 15.6 0.1 1.6 2 0 0 2 2 2 1 Podoplanin C2-set_2 PF08205.12 CBY08677.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CBY08677.1 - 0.092 12.3 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain PMP1_2 PF08114.11 CBY08677.1 - 1.1 9.1 3.7 0.35 10.7 0.7 1.7 2 0 0 2 2 2 0 ATPase proteolipid family EGF_CA PF07645.15 CBY08678.1 - 5.1e-214 692.3 566.0 3.1e-11 43.3 5.8 36.5 35 1 0 35 35 35 35 Calcium-binding EGF domain EGF_3 PF12947.7 CBY08678.1 - 6.3e-98 320.7 499.1 2e-08 34.3 11.7 38.7 36 4 3 39 39 39 32 EGF domain cEGF PF12662.7 CBY08678.1 - 2.8e-67 222.2 363.6 1.7e-07 31.0 0.5 38.5 38 3 0 38 38 38 28 Complement Clr-like EGF-like EGF PF00008.27 CBY08678.1 - 6.8e-21 74.2 471.9 0.00012 22.2 7.2 37.3 36 1 0 36 36 36 24 EGF-like domain FXa_inhibition PF14670.6 CBY08678.1 - 3.7e-20 71.9 480.0 0.016 15.4 11.5 36.4 33 2 2 35 35 35 25 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY08678.1 - 3.4e-11 43.3 439.5 0.00021 21.8 5.4 40.3 42 0 0 42 42 42 21 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY08678.1 - 7.9e-07 29.0 59.3 6.2e-05 23.0 2.4 34.2 35 1 0 35 35 35 16 MSP1 EGF domain 1 ITI_HC_C PF06668.12 CBY08678.1 - 8e-06 25.6 0.2 1.2e-05 25.0 0.2 1.2 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus DAG1 PF05454.11 CBY08679.1 - 0.11 11.8 0.1 0.12 11.7 0.1 1.0 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Fungus-induced PF10917.8 CBY08679.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungus-induced protein Aldedh PF00171.22 CBY08680.1 - 2e-20 72.8 0.0 2.2e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CBY08681.1 - 2.6e-46 158.1 0.0 3.4e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3421 PF11901.8 CBY08683.1 - 1.9e-17 63.3 0.0 1.1e-05 25.4 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) zf-C4 PF00105.18 CBY08685.1 - 4.1e-30 104.0 11.8 7.7e-30 103.2 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY08685.1 - 7.3e-13 48.6 0.0 1.2e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Glyoxalase PF00903.25 CBY08686.1 - 8.5e-19 68.0 0.0 3.2e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CBY08686.1 - 3.5e-13 49.8 0.0 1.6e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CBY08686.1 - 2.3e-07 31.1 0.0 0.013 15.6 0.0 2.9 3 1 0 3 3 3 2 Glyoxalase-like domain CDC45 PF02724.14 CBY08686.1 - 0.21 9.9 0.0 0.28 9.4 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein ShK PF01549.24 CBY08687.1 - 1.9e-12 47.5 62.9 0.0015 19.0 5.7 5.7 5 1 0 5 5 5 5 ShK domain-like Plasmodium_Vir PF05795.11 CBY08687.1 - 3.3 7.1 5.5 5.6 6.3 5.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein EF-hand_1 PF00036.32 CBY08689.1 - 3.6e-12 44.9 0.0 0.00042 19.7 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CBY08689.1 - 4.9e-11 42.9 0.3 4.5e-10 39.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY08689.1 - 1.9e-10 39.8 0.1 4.3e-05 23.1 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY08689.1 - 4.2e-07 29.2 2.4 0.00012 21.4 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY08689.1 - 4.8e-07 29.5 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 CBY08689.1 - 0.0023 17.9 0.1 0.0046 16.9 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY08689.1 - 0.014 15.7 0.2 0.036 14.4 0.1 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TrbC PF04956.13 CBY08691.1 - 0.3 11.3 8.4 1.1 9.6 3.8 3.1 2 2 1 3 3 3 0 TrbC/VIRB2 family CrgA PF06781.12 CBY08691.1 - 0.76 9.9 3.6 3.8 7.6 0.6 2.6 2 1 1 3 3 3 0 Cell division protein CrgA Peptidase_M14 PF00246.24 CBY08692.1 - 5.8e-83 279.0 0.1 5.8e-83 279.0 0.1 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 CBY08692.1 - 1.6e-07 31.5 0.1 2.9e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 CBY08692.1 - 4.3e-05 23.4 0.1 8.1e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 CBY08692.1 - 0.0064 15.6 0.4 0.029 13.5 0.5 2.0 2 1 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family SET PF00856.28 CBY08693.1 - 3.8e-11 43.7 0.0 1.2e-10 42.1 0.0 1.8 1 1 0 1 1 1 1 SET domain Peptidase_M14 PF00246.24 CBY08694.1 - 6.6e-73 246.0 2.0 8.4e-73 245.7 2.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY08694.1 - 3.9e-13 49.6 0.4 8.6e-13 48.5 0.4 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Trypsin PF00089.26 CBY08695.1 - 8.5e-143 473.7 25.6 5.3e-51 173.5 2.9 3.6 4 0 0 4 4 4 3 Trypsin Trypsin_2 PF13365.6 CBY08695.1 - 6e-22 79.2 6.7 1.9e-06 28.8 0.0 4.4 4 0 0 4 4 4 3 Trypsin-like peptidase domain Peptidase_C4 PF00863.19 CBY08695.1 - 0.35 10.1 1.2 0.92 8.8 0.1 2.2 2 0 0 2 2 2 0 Peptidase family C4 MotY_N PF18393.1 CBY08696.1 - 0.064 13.4 0.0 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 MotY N-terminal domain DUF2540 PF10802.8 CBY08696.1 - 0.071 13.2 0.3 2.2 8.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Chibby PF14645.6 CBY08696.1 - 0.15 12.5 0.3 0.78 10.2 0.1 2.2 2 0 0 2 2 2 0 Chibby family NCD1 PF04904.13 CBY08697.1 - 6.2e-34 115.8 0.3 1.1e-33 115.0 0.3 1.5 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) CbbQ_C PF08406.10 CBY08697.1 - 0.0044 17.2 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Pil1 PF13805.6 CBY08697.1 - 0.082 12.4 0.7 0.3 10.5 0.6 1.8 1 1 1 2 2 2 0 Eisosome component PIL1 SseC PF04888.12 CBY08697.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family RRM_1 PF00076.22 CBY08698.1 - 8.3e-19 67.2 0.0 2.1e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 CBY08698.1 - 3.1e-17 63.1 6.6 3.8e-17 62.8 4.8 1.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G Nup35_RRM_2 PF14605.6 CBY08698.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cytochrome_P460 PF16694.5 CBY08698.1 - 0.17 12.2 2.0 1 9.7 1.2 2.3 2 1 0 2 2 2 0 Cytochrome P460 WD40 PF00400.32 CBY08699.1 - 2.7e-06 28.0 6.8 0.36 11.8 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY08699.1 - 6.9e-05 23.1 2.1 0.023 15.0 0.1 4.2 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SART-1 PF03343.13 CBY08700.1 - 1.4e-58 199.0 25.4 1.9e-36 125.9 11.7 2.0 2 0 0 2 2 2 2 SART-1 family DUF753 PF05444.12 CBY08702.1 - 1.7 8.6 10.2 1.4 8.9 0.3 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF753) Sulfotransfer_1 PF00685.27 CBY08703.1 - 3.8e-09 36.4 0.0 1.2e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY08703.1 - 1.1e-05 25.9 0.1 0.038 14.4 0.0 3.2 2 1 1 3 3 3 3 Sulfotransferase family Costars PF14705.6 CBY08705.1 - 8.8e-26 89.9 0.1 1.3e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 Costars Methyltranf_PUA PF13636.6 CBY08705.1 - 0.076 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF Cadherin_3 PF16184.5 CBY08706.1 - 1.6e-189 617.3 38.3 1.2e-25 89.7 0.4 15.0 15 0 0 15 15 15 12 Cadherin-like Calx-beta PF03160.14 CBY08706.1 - 8.7e-67 221.6 19.0 4.7e-14 52.4 0.0 6.5 5 0 0 5 5 5 5 Calx-beta domain Big_9 PF17963.1 CBY08706.1 - 3.5e-10 40.5 15.6 0.00041 21.0 0.1 9.9 10 0 0 10 10 10 2 Bacterial Ig domain Cadherin_4 PF17803.1 CBY08706.1 - 2.2e-08 34.6 4.3 1.3 9.7 0.0 8.4 9 0 0 9 9 9 2 Bacterial cadherin-like domain Filamin PF00630.19 CBY08706.1 - 0.15 12.9 1.9 61 4.5 0.1 5.0 4 1 0 4 4 4 0 Filamin/ABP280 repeat OLF PF02191.16 CBY08707.1 - 1.3e-56 191.9 2.2 1.8e-56 191.5 2.2 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Sushi PF00084.20 CBY08708.1 - 0.97 10.1 6.6 1.9 9.1 6.6 1.5 1 1 0 1 1 1 0 Sushi repeat (SCR repeat) GyrB_insert PF18053.1 CBY08709.1 - 0.011 15.7 0.0 0.063 13.2 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain SATase_N PF06426.14 CBY08709.1 - 0.38 11.1 3.8 1.1 9.7 0.4 3.5 4 1 0 4 4 4 0 Serine acetyltransferase, N-terminal Innexin PF00876.18 CBY08710.1 - 2.2e-05 23.9 0.1 2.2e-05 23.9 0.1 2.1 2 1 0 2 2 2 1 Innexin I_LWEQ PF01608.17 CBY08711.1 - 0.02 15.2 1.5 0.024 14.9 1.5 1.2 1 0 0 1 1 1 0 I/LWEQ domain Acyl-CoA_dh_1 PF00441.24 CBY08712.1 - 6.7e-40 136.7 0.7 1.2e-39 135.9 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY08712.1 - 3.4e-23 82.5 0.0 7.6e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY08712.1 - 3.2e-21 75.3 0.0 5.4e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY08712.1 - 6.5e-13 49.1 0.0 1.1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3029 PF11230.8 CBY08712.1 - 0.17 10.2 0.1 0.25 9.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) DUF4946 PF16304.5 CBY08713.1 - 0.25 11.0 2.9 0.31 10.7 2.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4946) Na_Ca_ex PF01699.24 CBY08714.1 - 4.4e-29 101.4 13.8 6.1e-29 100.9 13.8 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF347 PF03988.12 CBY08714.1 - 0.034 14.3 0.5 0.088 13.0 0.5 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Herpes_LMP1 PF05297.11 CBY08714.1 - 0.038 13.2 1.4 0.081 12.1 1.4 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Na_Ca_ex PF01699.24 CBY08715.1 - 1.6e-31 109.3 19.3 2.2e-31 108.9 19.3 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Cadherin_C_2 PF16492.5 CBY08715.1 - 0.0044 17.7 0.9 0.014 16.1 0.9 1.9 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal CbiQ PF02361.16 CBY08715.1 - 7.2 6.2 10.4 2.7 7.6 1.4 2.2 2 0 0 2 2 2 0 Cobalt transport protein DUF2891 PF11199.8 CBY08716.1 - 0.059 12.3 0.0 0.065 12.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) DUF3285 PF11688.8 CBY08717.1 - 0.24 11.3 0.7 0.42 10.6 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Chordopox_A13L PF05961.11 CBY08719.1 - 0.016 15.4 0.4 0.04 14.2 0.3 1.8 1 1 0 1 1 1 0 Chordopoxvirus A13L protein Phage_holin_2_4 PF16082.5 CBY08719.1 - 0.033 13.9 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like OATP PF03137.20 CBY08719.1 - 0.049 11.9 0.5 0.056 11.7 0.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PspB PF06667.12 CBY08719.1 - 0.05 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein B DUF5330 PF17264.2 CBY08720.1 - 0.05 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5330) TipAS PF07739.13 CBY08720.1 - 0.096 13.2 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain MIF4G_like_2 PF09090.11 CBY08722.1 - 3.2e-06 26.8 0.1 5e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 CBY08722.1 - 0.00017 21.3 0.0 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain DUF667 PF05018.13 CBY08723.1 - 4.2e-93 310.2 0.9 4.7e-93 310.1 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) MIF4G PF02854.19 CBY08724.1 - 1e-06 28.5 0.1 1.2e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 MIF4G domain AAA_6 PF12774.7 CBY08725.1 - 1.3e-116 389.2 0.1 1.9e-115 385.3 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBY08725.1 - 2.4e-78 264.0 4.5 2.4e-78 264.0 4.5 4.6 6 1 0 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CBY08725.1 - 4.2e-51 173.2 6.6 4.2e-51 173.2 6.6 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CBY08725.1 - 8.5e-28 97.4 0.0 2.8e-27 95.7 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 CBY08725.1 - 4e-25 88.6 10.6 1.1e-24 87.1 10.6 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 CBY08725.1 - 6.1e-21 74.7 0.0 1.3e-15 57.4 0.0 4.7 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_5 PF07728.14 CBY08725.1 - 3.3e-18 66.0 0.0 6.4e-05 23.0 0.0 6.1 4 2 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY08725.1 - 7.2e-09 36.0 0.1 0.56 10.5 0.0 5.8 4 0 0 4 4 4 3 AAA domain AAA PF00004.29 CBY08725.1 - 2e-08 34.7 0.6 0.53 10.7 0.0 5.6 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY08725.1 - 2.3e-05 24.9 10.8 1.7 9.0 0.0 6.6 7 0 0 7 7 5 2 AAA ATPase domain AAA_24 PF13479.6 CBY08725.1 - 0.00039 20.2 5.2 0.0037 17.0 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 CBY08725.1 - 0.0014 19.2 1.3 5.8 7.5 0.0 5.1 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.22 CBY08725.1 - 0.0025 18.2 0.1 22 5.5 0.0 4.1 3 0 0 3 3 3 0 RNA helicase Dynein_heavy PF03028.15 CBY08725.1 - 0.0042 17.2 0.0 0.95 9.6 0.0 3.7 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain KTI12 PF08433.10 CBY08725.1 - 0.005 16.3 0.7 0.18 11.2 0.0 3.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ABC_tran PF00005.27 CBY08725.1 - 0.049 14.2 13.5 1.5 9.3 0.0 6.0 5 0 0 5 5 5 0 ABC transporter Utp12 PF04003.12 CBY08725.1 - 0.12 12.7 3.2 6.1 7.2 0.0 4.5 4 0 0 4 4 3 0 Dip2/Utp12 Family DASH_Dad4 PF08650.10 CBY08725.1 - 2 8.4 4.2 11 6.1 0.4 4.0 3 0 0 3 3 3 0 DASH complex subunit Dad4 PMEI PF04043.15 CBY08725.1 - 5 7.5 7.6 2.4 8.5 0.0 3.9 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor NAD_binding_6 PF08030.12 CBY08725.1 - 6.7 6.8 5.7 7.5 6.7 0.0 3.2 3 0 0 3 3 2 0 Ferric reductase NAD binding domain TTL PF03133.15 CBY08726.1 - 1.1e-39 136.3 2.4 1.5e-39 135.9 2.4 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY08726.1 - 6e-07 29.0 0.1 1e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 CBY08726.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 CBY08726.1 - 0.045 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Sdh_cyt PF01127.22 CBY08727.1 - 8.5e-17 61.3 5.5 1e-16 61.0 5.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DnaJ PF00226.31 CBY08728.1 - 9e-21 73.8 6.2 3.4e-20 71.9 2.7 2.8 2 0 0 2 2 2 1 DnaJ domain DUF5302 PF17227.2 CBY08728.1 - 0.072 14.1 0.6 0.072 14.1 0.6 5.5 5 0 0 5 5 5 0 Family of unknown function (DUF5302) Motile_Sperm PF00635.26 CBY08729.1 - 8.4e-09 35.3 1.0 2e-08 34.0 0.1 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 CBY08729.1 - 0.023 14.9 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1754 PF08555.10 CBY08730.1 - 5.3 7.9 15.6 9.7 7.1 15.6 1.5 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) PhoLip_ATPase_C PF16212.5 CBY08731.1 - 3.8e-40 138.2 4.7 3.8e-40 138.2 4.7 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBY08731.1 - 4.5e-19 67.9 0.1 4.5e-19 67.9 0.1 2.1 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CBY08731.1 - 2.4e-11 43.5 0.0 6.5e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBY08731.1 - 7.2e-11 42.0 0.2 3.9e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY08731.1 - 4.6e-10 40.2 3.3 5.6e-06 26.8 2.3 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY08731.1 - 0.00063 19.5 0.2 0.003 17.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Carbam_trans_C PF16861.5 CBY08731.1 - 0.17 11.5 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase C-terminus PhoLip_ATPase_C PF16212.5 CBY08732.1 - 1.1e-14 54.8 14.3 1.5e-14 54.3 14.3 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal MOZ_SAS PF01853.18 CBY08733.1 - 3.2e-79 264.7 0.3 4.8e-79 264.2 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY08733.1 - 5.5e-22 77.1 2.3 1.5e-21 75.8 2.3 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CBY08733.1 - 1.1e-20 73.2 0.2 2.9e-20 71.9 0.2 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CBY08733.1 - 0.00028 21.2 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY08733.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_16 PF05301.11 CBY08733.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Med20 PF08612.11 CBY08734.1 - 3.4e-23 82.2 0.1 4.1e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex PSCyt3 PF07627.11 CBY08734.1 - 0.081 13.2 0.1 0.24 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) DUF445 PF04286.12 CBY08735.1 - 4.5e-05 23.4 1.0 6.7e-05 22.9 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1641 PF07849.11 CBY08735.1 - 0.045 13.6 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) GerD PF17898.1 CBY08735.1 - 0.072 13.0 0.1 6.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Spore germination GerD central core domain YtzH PF14165.6 CBY08735.1 - 0.082 13.3 3.6 13 6.3 0.4 3.5 1 1 3 4 4 4 0 YtzH-like protein Peptidase_S10 PF00450.22 CBY08736.1 - 0.068 12.6 0.4 0.12 11.7 0.4 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase zf-Mss51 PF13824.6 CBY08736.1 - 0.17 12.0 2.3 0.34 11.0 0.4 2.4 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 CBY08736.1 - 0.24 11.3 3.4 0.16 11.9 1.0 1.9 2 0 0 2 2 2 0 HIT zinc finger zf-B_box PF00643.24 CBY08736.1 - 0.25 11.5 7.4 7 6.9 0.2 3.3 3 0 0 3 3 3 0 B-box zinc finger DUF4428 PF14471.6 CBY08736.1 - 0.32 10.9 6.7 1.9 8.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-UBR PF02207.20 CBY08736.1 - 0.68 10.1 4.4 2.4 8.4 4.4 1.9 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF4541 PF15074.6 CBY08737.1 - 1.6e-29 102.3 0.6 3.3e-29 101.3 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) MAPKK1_Int PF08923.10 CBY08738.1 - 9.1e-06 25.5 0.1 1.3e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting 60KD_IMP PF02096.20 CBY08738.1 - 0.014 15.3 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein zf-C3HC PF07967.13 CBY08739.1 - 4.2e-17 62.4 0.0 3.1e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Dsl1_N PF11988.8 CBY08739.1 - 0.069 12.1 0.2 0.13 11.2 0.0 1.5 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal MCR_beta_N PF02783.15 CBY08740.1 - 0.087 12.4 0.2 0.087 12.4 0.2 2.2 3 0 0 3 3 3 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Allexi_40kDa PF05549.11 CBY08740.1 - 0.49 9.9 2.8 1.2 8.6 2.8 1.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein BROMI PF14961.6 CBY08743.1 - 0.34 8.3 0.7 0.45 7.9 0.7 1.0 1 0 0 1 1 1 0 Broad-minded protein EGF_2 PF07974.13 CBY08744.1 - 0.035 14.5 2.9 0.035 14.5 2.9 3.5 2 1 0 2 2 2 0 EGF-like domain Ank_2 PF12796.7 CBY08745.1 - 4.4e-14 52.8 2.8 2.1e-05 25.0 0.1 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY08745.1 - 1.9e-10 41.1 0.3 0.045 14.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY08745.1 - 1.6e-09 37.8 0.1 0.0051 17.1 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY08745.1 - 5.7e-07 29.4 0.1 0.42 11.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CBY08745.1 - 4.4e-06 26.9 0.2 0.08 13.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ion_trans PF00520.31 CBY08747.1 - 9e-120 398.4 64.8 1.1e-48 165.7 14.1 3.0 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 CBY08747.1 - 2.7e-05 23.1 5.8 2.7e-05 23.1 5.8 6.1 4 2 1 6 6 6 5 Polycystin cation channel Annexin PF00191.20 CBY08748.1 - 2.7e-44 149.1 0.1 3e-12 46.4 0.0 4.1 4 0 0 4 4 4 4 Annexin Lectin_C PF00059.21 CBY08749.1 - 1.6e-14 54.5 0.4 3.7e-14 53.4 0.4 1.6 1 0 0 1 1 1 1 Lectin C-type domain EGF_CA PF07645.15 CBY08749.1 - 0.00012 22.2 1.9 0.00012 22.2 1.9 3.5 2 1 0 2 2 2 1 Calcium-binding EGF domain CD20 PF04103.15 CBY08750.1 - 0.0023 18.0 6.2 0.003 17.7 6.2 1.2 1 0 0 1 1 1 1 CD20-like family Tetraspanin PF00335.20 CBY08750.1 - 0.06 13.1 13.2 0.098 12.4 13.3 1.3 1 1 0 1 1 1 0 Tetraspanin family DUF202 PF02656.15 CBY08750.1 - 4 7.9 9.2 83 3.7 8.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) TSP_1 PF00090.19 CBY08751.1 - 0.00017 21.7 7.6 0.00038 20.6 7.6 1.7 1 1 0 1 1 1 1 Thrombospondin type 1 domain CAP PF00188.26 CBY08753.1 - 1.6e-10 41.9 1.4 2.9e-10 41.0 1.4 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_M13_N PF05649.13 CBY08754.1 - 3.7e-78 263.9 0.0 7.3e-78 262.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Pkinase PF00069.25 CBY08754.1 - 8e-55 186.0 0.0 1.5e-54 185.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M13 PF01431.21 CBY08754.1 - 9.2e-47 159.3 1.9 1.9e-46 158.3 1.9 1.5 1 0 0 1 1 1 1 Peptidase family M13 Pkinase_Tyr PF07714.17 CBY08754.1 - 1.9e-33 115.8 0.0 3.2e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY08754.1 - 6.9e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY08754.1 - 1.6e-05 24.4 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY08754.1 - 0.0022 16.8 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EcKinase PF02958.20 CBY08754.1 - 0.058 12.7 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase S_layer_N PF05123.12 CBY08754.1 - 0.37 10.6 1.4 0.83 9.5 0.1 2.0 2 0 0 2 2 2 0 S-layer like family, N-terminal region SPECT1 PF18680.1 CBY08754.1 - 9.1 5.9 7.0 0.73 9.5 0.0 2.7 4 0 0 4 4 4 0 Plasmodium host cell traversal SPECT1 Torsin PF06309.11 CBY08755.1 - 2.2e-28 98.9 0.0 4.3e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_5 PF07728.14 CBY08755.1 - 0.0051 16.8 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CBY08755.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 CBY08755.1 - 0.026 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 CBY08755.1 - 0.029 14.8 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CBY08755.1 - 0.034 14.2 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CBY08755.1 - 0.039 14.0 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 CBY08755.1 - 0.063 12.5 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 CBY08755.1 - 0.066 13.5 0.0 0.78 10.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY08755.1 - 0.092 13.1 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Adeno_IVa2 PF02456.15 CBY08755.1 - 0.18 10.5 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein BolA PF01722.18 CBY08756.1 - 2.2e-15 56.6 0.2 1.8e-14 53.8 0.2 1.9 1 1 0 1 1 1 1 BolA-like protein SRP68 PF16969.5 CBY08757.1 - 1.6e-81 275.0 12.6 3.3e-79 267.4 12.6 2.1 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 BACK PF07707.15 CBY08758.1 - 0.0011 19.0 0.4 0.0042 17.2 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 CBY08758.1 - 0.17 12.2 2.7 0.88 10.0 0.0 3.2 4 0 0 4 4 4 0 Kelch motif CDC73_C PF05179.14 CBY08759.1 - 0.019 14.6 0.2 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal SPA PF08616.10 CBY08760.1 - 8.6e-10 38.6 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 CBY08760.1 - 2.3e-07 31.0 0.6 4.3e-05 23.5 0.2 3.0 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 CBY08760.1 - 4.3e-06 25.7 0.1 1.3e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Transport protein Avl9 Sedlin_N PF04628.13 CBY08761.1 - 2.2e-22 79.6 0.6 2.7e-22 79.3 0.6 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CBY08761.1 - 0.018 15.0 0.2 0.018 15.0 0.2 1.2 1 0 0 1 1 1 0 Sybindin-like family DUF1131 PF06572.12 CBY08761.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) Ribosomal_S14 PF00253.21 CBY08762.1 - 0.052 13.3 0.1 0.2 11.5 0.1 2.0 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e Pro_isomerase PF00160.21 CBY08763.1 - 1.9e-46 158.2 0.4 2.2e-46 158.0 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MitoNEET_N PF10660.9 CBY08764.1 - 4.3e-11 42.7 0.0 5.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus zf-CDGSH PF09360.10 CBY08764.1 - 2.6e-09 37.1 0.2 4e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type PPTA PF01239.22 CBY08765.1 - 5.7e-29 99.0 11.5 1.9e-08 33.7 0.1 5.2 4 1 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat ZapC PF07126.12 CBY08765.1 - 0.0039 16.8 0.2 0.0068 16.0 0.2 1.4 1 0 0 1 1 1 1 Cell-division protein ZapC HILPDA PF15220.6 CBY08765.1 - 0.014 15.5 0.0 6.3 7.0 0.0 3.5 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated FBA PF04300.13 CBY08765.1 - 0.037 13.7 0.3 0.082 12.6 0.3 1.7 1 1 0 1 1 1 0 F-box associated region Auto_anti-p27 PF06677.12 CBY08766.1 - 6.3e-16 58.3 2.7 1e-15 57.6 2.7 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_4 PF15227.6 CBY08766.1 - 0.0014 18.8 0.3 0.0026 17.9 0.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING BAF PF02961.14 CBY08767.1 - 8e-38 128.8 0.3 9e-38 128.6 0.3 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor GHMP_kinases_N PF00288.26 CBY08768.1 - 0.0038 17.4 1.6 0.16 12.2 0.3 2.4 2 0 0 2 2 2 2 GHMP kinases N terminal domain DUF92 PF01940.16 CBY08768.1 - 0.0075 15.7 0.3 0.009 15.5 0.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 PsbX PF06596.11 CBY08768.1 - 0.36 10.9 1.8 0.59 10.2 1.8 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Scramblase PF03803.15 CBY08769.1 - 8.5e-05 21.9 0.0 9.4e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Scramblase Spc7 PF08317.11 CBY08770.1 - 0.0076 15.2 11.9 0.0084 15.0 11.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein MIP-T3_C PF17749.1 CBY08770.1 - 0.0089 16.0 12.0 0.0089 16.0 12.0 1.4 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Spc29 PF17082.5 CBY08770.1 - 0.011 15.6 2.1 0.012 15.5 2.1 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 Fez1 PF06818.15 CBY08770.1 - 0.011 16.1 10.2 0.014 15.9 10.2 1.0 1 0 0 1 1 1 0 Fez1 MPS2 PF17060.5 CBY08770.1 - 0.015 14.6 6.0 0.016 14.5 6.0 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 UPF0242 PF06785.11 CBY08770.1 - 0.019 15.1 10.1 0.019 15.1 10.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HrpB7 PF09486.10 CBY08770.1 - 0.023 15.1 1.2 0.023 15.1 1.2 1.3 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HMMR_N PF15905.5 CBY08770.1 - 0.024 14.1 12.8 0.025 14.0 12.8 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 CBY08770.1 - 0.048 13.7 4.6 0.058 13.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 CBY08770.1 - 0.076 13.7 3.9 0.12 13.1 3.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CEP63 PF17045.5 CBY08770.1 - 0.086 12.7 9.8 0.099 12.5 9.8 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa LCIB_C_CA PF18599.1 CBY08770.1 - 0.21 10.8 2.9 0.23 10.8 2.9 1.1 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases RNAse_A_bac PF18431.1 CBY08770.1 - 0.4 11.6 2.2 0.46 11.5 2.0 1.3 1 1 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain DUF745 PF05335.13 CBY08770.1 - 0.43 10.3 6.1 0.57 9.9 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 CBY08770.1 - 0.44 10.1 4.0 0.46 10.0 4.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit GrpE PF01025.19 CBY08770.1 - 0.88 9.2 12.3 1.2 8.8 12.3 1.3 1 1 0 1 1 1 0 GrpE OmpH PF03938.14 CBY08770.1 - 1 9.7 15.9 1.2 9.4 15.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM76 PF16046.5 CBY08770.1 - 1.5 8.1 11.0 1.9 7.8 11.0 1.2 1 0 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 CBY08770.1 - 1.5 8.6 12.5 1.7 8.4 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF641 PF04859.12 CBY08770.1 - 1.6 9.1 8.8 2.6 8.4 6.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3552 PF12072.8 CBY08770.1 - 1.8 7.9 13.4 2.9 7.3 13.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Csm1_N PF18504.1 CBY08770.1 - 2.5 8.5 10.4 0.29 11.5 3.4 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain Atg14 PF10186.9 CBY08770.1 - 3.3 6.7 6.7 2.9 6.9 5.8 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2 PF00096.26 CBY08771.1 - 6.6e-08 32.6 41.0 0.0068 16.8 0.4 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY08771.1 - 1.9e-07 31.2 33.8 0.00059 20.1 0.4 5.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBY08771.1 - 9.7e-05 22.0 4.2 9.7e-05 22.0 4.2 4.8 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBY08771.1 - 0.00014 22.4 40.0 0.15 13.0 2.3 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY08771.1 - 0.056 13.8 10.1 0.19 12.0 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY08771.1 - 0.09 13.2 0.0 0.09 13.2 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CBY08771.1 - 0.57 10.5 14.4 0.86 9.9 1.0 3.2 2 1 1 3 3 3 0 C2H2-type zinc ribbon GAGA PF09237.11 CBY08771.1 - 0.72 9.7 4.7 12 5.8 0.1 3.1 1 1 2 3 3 3 0 GAGA factor zf-3CxxC_2 PF17180.4 CBY08772.1 - 6.2e-26 90.9 12.2 6.2e-26 90.9 12.2 1.7 2 0 0 2 2 2 1 Zinc-binding domain zf-CCHC_2 PF13696.6 CBY08772.1 - 3.7e-11 42.6 2.7 1.4e-10 40.8 2.7 2.1 1 0 0 1 1 1 1 Zinc knuckle UPF0515 PF15135.6 CBY08772.1 - 0.00038 19.9 7.2 0.00049 19.5 7.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-3CxxC PF13695.6 CBY08772.1 - 0.0022 18.4 17.7 0.04 14.4 16.8 2.9 2 1 0 2 2 2 1 Zinc-binding domain zf-CCHC PF00098.23 CBY08772.1 - 0.014 15.4 0.8 0.014 15.4 0.8 3.2 3 0 0 3 3 3 0 Zinc knuckle PPP1R35_C PF15503.6 CBY08773.1 - 1.1e-34 119.3 0.6 2e-34 118.5 0.6 1.4 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus BcrAD_BadFG PF01869.20 CBY08774.1 - 5.4e-22 78.5 0.1 6.4e-22 78.3 0.1 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family TAL_effector PF03377.13 CBY08774.1 - 0.0074 16.6 0.5 0.019 15.2 0.0 1.9 2 0 0 2 2 2 1 TAL effector repeat ROK PF00480.20 CBY08774.1 - 0.025 14.0 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 ROK family ORMDL PF04061.14 CBY08775.1 - 1.1e-49 167.7 5.6 1.3e-49 167.5 5.6 1.0 1 0 0 1 1 1 1 ORMDL family CitMHS PF03600.16 CBY08775.1 - 0.17 11.0 1.1 0.21 10.7 1.1 1.1 1 0 0 1 1 1 0 Citrate transporter TMEM208_SND2 PF05620.11 CBY08775.1 - 0.56 10.0 4.7 0.28 10.9 0.5 2.0 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 ArsA_ATPase PF02374.15 CBY08776.1 - 1.2e-102 343.2 0.0 1.5e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CBY08776.1 - 5.1e-11 42.8 0.2 2.1e-10 40.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 CBY08776.1 - 1.1e-09 38.4 0.0 2e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CBY08776.1 - 6.3e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 CBY08776.1 - 0.00064 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 CBY08776.1 - 0.00069 19.1 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 CBY08776.1 - 0.0021 17.7 0.1 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CBY08776.1 - 0.078 12.3 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Sucrose_synth PF00862.19 CBY08777.1 - 0.00052 18.5 0.3 0.00092 17.6 0.3 1.3 1 0 0 1 1 1 1 Sucrose synthase CAP_N PF01213.19 CBY08777.1 - 0.56 9.6 8.5 0.078 12.4 3.6 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PPC PF04151.15 CBY08778.1 - 0.16 13.1 0.0 0.34 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Enolase_C PF00113.22 CBY08779.1 - 2.2e-147 490.0 0.0 2.9e-147 489.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CBY08779.1 - 3e-55 185.9 1.4 4e-55 185.5 0.6 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CBY08779.1 - 8.9e-08 32.0 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CBY08779.1 - 0.0021 17.3 0.0 0.007 15.5 0.0 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus RdRP_5 PF07925.11 CBY08779.1 - 0.16 9.3 0.0 0.23 8.8 0.0 1.1 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 Alpha-amylase_C PF02806.18 CBY08780.1 - 9.8e-22 77.2 0.0 2.9e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 CBY08780.1 - 1.2e-12 48.0 0.1 4.7e-08 33.0 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 CBY08780.1 - 4.5e-08 33.3 0.1 1.3e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.18 CBY08780.1 - 0.092 12.2 0.4 4.5 6.6 0.0 2.3 1 1 1 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Tubulin PF00091.25 CBY08781.1 - 8.2e-68 228.5 0.0 1.6e-67 227.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY08781.1 - 3.8e-50 169.3 0.1 6e-50 168.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY08781.1 - 0.00063 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CBY08781.1 - 0.024 14.9 0.1 0.059 13.7 0.1 1.7 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain Sugar_tr PF00083.24 CBY08782.1 - 8.9e-36 123.7 16.8 2.9e-35 122.0 16.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY08782.1 - 2.2e-13 49.9 42.1 3.4e-09 36.1 17.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Trypsin PF00089.26 CBY08783.1 - 1.3e-55 188.6 0.0 2.1e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY08783.1 - 2.4e-05 24.7 0.0 4.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 CBY08783.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 HCMV_UL139 PF12507.8 CBY08785.1 - 0.035 14.5 0.1 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein PIF2 PF04631.12 CBY08785.1 - 0.048 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Per os infectivity factor 2 TPR_14 PF13428.6 CBY08786.1 - 4.8e-18 64.3 6.6 0.083 13.7 0.1 12.3 8 4 5 13 13 12 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY08786.1 - 3e-13 49.6 9.5 0.00018 20.8 0.1 4.8 3 1 2 5 5 5 4 Tetratricopeptide repeat Suf PF05843.14 CBY08786.1 - 7.4e-09 36.0 28.1 0.002 18.1 0.3 6.6 4 1 0 6 6 6 3 Suppressor of forked protein (Suf) TPR_8 PF13181.6 CBY08786.1 - 2.5e-07 30.4 12.0 1.1 9.6 0.1 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY08786.1 - 5.5e-07 29.8 10.1 0.00024 21.3 0.1 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY08786.1 - 4.9e-06 26.2 18.8 0.89 9.8 0.2 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY08786.1 - 1.5e-05 25.4 7.7 14 6.3 0.0 8.0 8 1 0 9 9 9 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBY08786.1 - 0.00011 22.2 20.5 0.073 13.1 0.9 7.0 5 2 2 7 7 7 2 Mad3/BUB1 homology region 1 NRDE-2 PF08424.10 CBY08786.1 - 0.00022 20.4 21.1 0.053 12.6 1.3 6.1 3 3 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 CBY08786.1 - 0.0015 18.7 0.2 7.6 6.8 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY08786.1 - 0.0016 18.6 4.2 84 3.9 0.1 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat AEP1 PF17049.5 CBY08786.1 - 0.0031 16.7 0.2 1.7 7.7 0.1 2.4 2 0 0 2 2 2 2 ATPase expression protein 1 TPR_16 PF13432.6 CBY08786.1 - 0.008 16.8 3.1 1.1 10.0 0.1 4.9 8 0 0 8 8 4 1 Tetratricopeptide repeat SNAP PF14938.6 CBY08786.1 - 0.027 13.9 9.4 0.051 13.0 0.2 4.7 4 2 3 8 8 8 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 CBY08786.1 - 0.041 13.9 1.0 4.8 7.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY08786.1 - 0.051 14.2 12.5 67 4.4 0.0 7.6 10 0 0 10 10 7 0 Tetratricopeptide repeat DALR_1 PF05746.15 CBY08786.1 - 0.13 12.5 2.8 1.1 9.5 0.4 3.4 2 1 0 2 2 2 0 DALR anticodon binding domain Exonuc_VII_S PF02609.16 CBY08786.1 - 0.21 11.6 1.5 4.7 7.3 0.0 3.8 4 0 0 4 4 3 0 Exonuclease VII small subunit LMBR1 PF04791.16 CBY08786.1 - 0.79 8.5 2.4 9.9 4.9 0.0 2.5 2 1 1 3 3 3 0 LMBR1-like membrane protein C2 PF00168.30 CBY08787.1 - 2.7e-39 133.6 0.0 2.4e-17 63.1 0.0 5.5 4 1 0 4 4 4 4 C2 domain FerB PF08150.12 CBY08787.1 - 1.7e-29 102.2 0.0 6.8e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 FerB (NUC096) domain Ferlin_C PF16165.5 CBY08787.1 - 7.1e-29 100.7 0.7 1.1e-22 80.7 0.0 2.5 1 1 1 2 2 2 2 Ferlin C-terminus DUF2154 PF09922.9 CBY08787.1 - 0.19 11.6 0.0 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Cell wall-active antibiotics response 4TMS YvqF ATP-synt_F PF01990.17 CBY08788.1 - 0.51 10.7 2.1 1 9.7 0.2 2.0 1 1 1 2 2 2 0 ATP synthase (F/14-kDa) subunit C2 PF00168.30 CBY08789.1 - 8.5e-28 96.7 0.5 3.8e-10 40.0 0.0 3.4 3 0 0 3 3 3 3 C2 domain FerI PF08151.12 CBY08789.1 - 5.7e-14 51.9 0.1 5.7e-14 51.9 0.1 2.5 3 0 0 3 3 3 1 FerI (NUC094) domain DEAD PF00270.29 CBY08790.1 - 1.5e-48 164.9 0.0 3.2e-48 163.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY08790.1 - 7.4e-27 93.9 0.5 3e-26 91.9 0.2 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY08790.1 - 4.3e-07 30.1 0.0 9.3e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY08790.1 - 0.0089 15.3 0.1 0.028 13.6 0.1 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Tra_M PF05261.11 CBY08790.1 - 0.086 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 TraM protein, DNA-binding zf-UBR PF02207.20 CBY08791.1 - 1.1e-17 63.9 11.2 1.1e-17 63.9 11.2 3.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CBY08791.1 - 2.6e-13 49.6 0.9 9.5e-13 47.7 0.1 2.4 3 0 0 3 3 3 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.6 CBY08791.1 - 0.0032 17.4 0.3 0.0032 17.4 0.3 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY08791.1 - 0.026 14.4 0.3 0.026 14.4 0.3 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) TMIE PF16038.5 CBY08791.1 - 0.063 13.1 0.5 0.71 9.7 1.0 2.7 2 0 0 2 2 2 0 TMIE protein RNA_pol PF00940.19 CBY08792.1 - 0.023 13.5 0.0 0.025 13.4 0.0 1.0 1 0 0 1 1 1 0 DNA-dependent RNA polymerase FAD_binding_2 PF00890.24 CBY08793.1 - 6e-118 394.5 2.8 6e-118 394.5 2.8 1.4 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 CBY08793.1 - 1.5e-39 134.9 1.8 2.2e-39 134.4 1.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 CBY08793.1 - 0.0002 20.7 0.4 0.0068 15.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBY08793.1 - 0.00034 19.8 4.1 0.028 13.5 0.9 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CBY08793.1 - 0.0028 16.9 0.1 0.0059 15.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CBY08793.1 - 0.003 16.8 0.6 0.73 9.0 0.1 2.6 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 CBY08793.1 - 0.061 12.9 1.4 0.16 11.5 0.1 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CBY08793.1 - 0.073 12.1 0.0 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 CBY08793.1 - 0.2 10.3 0.3 0.49 9.0 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Mre11_DNA_bind PF04152.14 CBY08794.1 - 1.3e-13 51.6 1.2 1.3e-13 51.6 1.2 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CBY08794.1 - 4.5e-13 50.2 1.3 1e-12 49.0 1.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBY08794.1 - 5.6e-09 36.4 0.0 3.1e-05 24.2 0.0 3.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FKBP_N_2 PF18023.1 CBY08794.1 - 0.0075 16.3 0.2 0.019 15.1 0.2 1.7 1 0 0 1 1 1 1 BDBT FKBP like N-terminal Sulfatase PF00884.23 CBY08795.1 - 1.2e-40 139.8 0.6 1.8e-40 139.3 0.6 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CBY08795.1 - 2.4e-06 27.8 0.4 1.7e-05 25.0 0.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 CBY08795.1 - 8.4e-05 23.3 1.7 0.0015 19.3 1.7 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 CBY08795.1 - 0.0039 15.9 0.0 0.0067 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CBY08795.1 - 0.045 13.3 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase EF-hand_1 PF00036.32 CBY08796.1 - 8.5e-14 50.0 0.0 0.00054 19.3 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CBY08796.1 - 7.4e-13 48.8 0.4 3.6e-10 40.2 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY08796.1 - 6e-12 44.5 0.3 0.00051 19.7 0.2 3.8 2 1 1 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBY08796.1 - 4.7e-09 36.0 0.3 7.9e-07 28.8 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY08796.1 - 3.7e-07 29.3 0.0 0.074 12.6 0.0 3.5 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 CBY08796.1 - 0.025 14.8 0.1 4.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 CBY08796.1 - 0.14 12.5 0.1 0.45 10.9 0.1 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3134 PF11332.8 CBY08796.1 - 0.21 11.9 1.1 0.29 11.5 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3134) KinB_sensor PF16767.5 CBY08797.1 - 0.1 13.1 5.0 5.9 7.4 0.1 2.9 2 1 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB TMPIT PF07851.13 CBY08797.1 - 1.6 7.9 5.7 3.6 6.7 5.7 1.5 1 0 0 1 1 1 0 TMPIT-like protein MRPL52 PF18699.1 CBY08797.1 - 3.1 8.1 6.4 38 4.6 0.0 3.0 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Sushi PF00084.20 CBY08798.1 - 2.1e-13 50.6 38.6 1.5e-07 31.9 3.7 5.1 5 0 0 5 5 5 4 Sushi repeat (SCR repeat) DUF2457 PF10446.9 CBY08798.1 - 0.68 9.0 7.6 1.1 8.3 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CUB PF00431.20 CBY08799.1 - 2.1e-65 217.9 7.5 4.3e-17 62.4 0.3 5.0 4 1 0 4 4 4 4 CUB domain EGF PF00008.27 CBY08799.1 - 1.7e-14 53.8 126.1 8.4e-08 32.4 9.9 9.5 9 0 0 9 9 9 6 EGF-like domain EGF_3 PF12947.7 CBY08799.1 - 7.7e-07 29.2 113.2 8e-05 22.8 9.0 8.8 7 1 1 8 8 8 5 EGF domain EGF_CA PF07645.15 CBY08799.1 - 0.00024 21.3 7.5 0.00024 21.3 7.5 8.9 5 3 3 8 8 8 3 Calcium-binding EGF domain hEGF PF12661.7 CBY08799.1 - 0.00052 20.6 10.4 0.00052 20.6 10.4 10.7 11 0 0 11 11 11 3 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY08799.1 - 0.0056 16.9 9.8 0.0056 16.9 9.8 9.1 6 2 3 9 9 9 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY08799.1 - 0.021 14.8 0.9 0.021 14.8 0.9 9.2 9 1 0 9 9 9 0 Complement Clr-like EGF-like RasGEF_N PF00618.20 CBY08800.1 - 6.9e-05 23.0 0.0 0.0014 18.8 0.0 3.1 2 0 0 2 2 2 1 RasGEF N-terminal motif RasGEF PF00617.19 CBY08800.1 - 0.00016 21.9 0.7 0.00053 20.2 0.7 2.0 1 0 0 1 1 1 1 RasGEF domain DUF4065 PF13274.6 CBY08800.1 - 5.5 7.9 7.0 0.71 10.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4065) TPR_2 PF07719.17 CBY08801.1 - 8.7e-06 25.5 25.1 0.57 10.4 0.3 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBY08801.1 - 0.14 13.0 4.7 1.1 10.2 0.7 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY08801.1 - 2.1 9.0 10.0 6.4 7.5 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY08801.1 - 4.1 8.0 7.6 2.7 8.6 1.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PseudoU_synth_1 PF01416.20 CBY08802.1 - 6e-14 52.4 0.0 1.5e-10 41.4 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase Gal-3-0_sulfotr PF06990.11 CBY08803.1 - 1.8e-37 129.2 0.6 2.5e-36 125.4 0.6 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY08803.1 - 4.6e-06 26.7 8.0 8.6e-06 25.8 3.6 3.1 2 1 0 2 2 2 1 Sulfotransferase family PAS_10 PF13596.6 CBY08803.1 - 0.071 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain IMCp PF12314.8 CBY08803.1 - 1.3 9.4 5.9 0.17 12.2 0.8 2.0 2 0 0 2 2 2 0 Inner membrane complex protein Acyl-CoA_dh_1 PF00441.24 CBY08804.1 - 7.7e-43 146.3 0.0 1.2e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY08804.1 - 4.2e-33 114.4 0.0 7.7e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY08804.1 - 3.6e-27 94.4 0.1 7.8e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY08804.1 - 1.2e-13 51.5 0.0 1.9e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBY08804.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal MRP-S28 PF10213.9 CBY08805.1 - 0.045 14.2 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Longin PF13774.6 CBY08806.1 - 4.2e-05 23.5 0.9 6.7e-05 22.9 0.2 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain DUF4515 PF14988.6 CBY08807.1 - 5.9e-12 45.9 41.5 5.9e-12 45.9 41.5 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF4515) RNA_pol_Rpb1_2 PF00623.20 CBY08808.1 - 2.6e-55 187.2 2.1 1e-35 123.4 0.0 2.8 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CBY08808.1 - 1.6e-25 90.2 7.3 1.3e-24 87.1 7.3 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CBY08809.1 - 2.5e-81 273.0 0.0 4.9e-81 272.1 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 CBY08809.1 - 2.3e-12 46.8 0.0 9.6e-12 44.8 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 CBY08809.1 - 1.9e-06 27.9 0.0 6.2e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 BUD22 PF09073.10 CBY08809.1 - 1.1 8.5 12.8 2.2 7.5 12.8 1.4 1 0 0 1 1 1 0 BUD22 polyprenyl_synt PF00348.17 CBY08810.1 - 4.5e-67 225.8 0.0 5.4e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DSX_dimer PF08828.10 CBY08810.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Doublesex dimerisation domain bZIP_1 PF00170.21 CBY08811.1 - 1.4e-08 34.7 13.0 2.8e-08 33.7 13.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY08811.1 - 0.00071 19.6 13.5 0.0014 18.7 13.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper AMP_N PF05195.16 CBY08812.1 - 3.8e-28 97.7 0.1 6.9e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 CBY08812.1 - 5.1e-17 62.3 0.0 9.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.24 CBY08813.1 - 1.8e-08 34.4 0.0 2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_C97 PF05903.14 CBY08814.1 - 2.4e-11 43.7 0.3 3.6e-11 43.1 0.3 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4300 PF14133.6 CBY08814.1 - 0.032 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) DUF4796 PF16044.5 CBY08814.1 - 0.13 11.8 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Pox_EPC_I2-L1 PF12575.8 CBY08814.1 - 0.16 12.2 0.1 0.32 11.2 0.0 1.6 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Pro_sub2 PF18513.1 CBY08818.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Prodomain subtilisin 2 OCRE PF17780.1 CBY08818.1 - 0.23 11.5 4.9 0.42 10.7 4.9 1.4 1 0 0 1 1 1 0 OCRE domain FoP_duplication PF13865.6 CBY08819.1 - 1.2 9.8 13.4 1.3 9.6 13.4 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Trypsin PF00089.26 CBY08820.1 - 2e-61 207.6 0.8 3.1e-61 207.0 0.8 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY08820.1 - 0.04 14.3 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) RanGAP1_C PF07834.11 CBY08821.1 - 0.059 13.0 0.6 0.11 12.1 0.6 1.4 1 0 0 1 1 1 0 RanGAP1 C-terminal domain PAN_3 PF08277.12 CBY08821.1 - 0.25 11.2 1.8 8.2 6.3 0.1 2.7 2 0 0 2 2 2 0 PAN-like domain DUF2964 PF11177.8 CBY08822.1 - 0.055 13.7 0.9 0.28 11.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) zf-H2C2_2 PF13465.6 CBY08823.1 - 1.2e-39 133.0 47.5 2.7e-08 33.9 1.8 7.2 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 CBY08823.1 - 4.8e-29 99.2 53.2 7.1e-06 26.2 0.7 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY08823.1 - 3.2e-21 74.2 48.0 0.003 18.3 6.2 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY08823.1 - 2.9e-11 43.3 26.0 0.068 13.5 2.5 6.2 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY08823.1 - 1.8e-07 31.3 36.4 0.035 14.5 2.4 5.7 6 0 0 6 6 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY08823.1 - 1.7e-06 27.9 50.6 0.047 13.7 0.2 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf_UBZ PF18439.1 CBY08823.1 - 0.00021 20.8 22.5 0.045 13.4 0.0 6.0 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 CBY08823.1 - 0.00051 20.3 11.5 0.057 13.7 0.7 3.1 2 1 1 3 3 3 2 zinc-finger-containing domain zinc_ribbon_15 PF17032.5 CBY08823.1 - 0.00061 20.5 14.7 0.84 10.4 1.5 3.3 1 1 1 3 3 3 3 zinc-ribbon family Scramblase PF03803.15 CBY08823.1 - 0.0017 17.7 2.6 0.53 9.5 0.2 2.1 1 1 1 2 2 2 2 Scramblase zf-C2H2_11 PF16622.5 CBY08823.1 - 0.0049 16.6 3.0 0.016 14.9 0.7 5.9 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-Paramyx-P PF13008.7 CBY08823.1 - 0.012 15.0 13.4 5.6 6.5 0.3 5.2 5 0 0 5 5 5 0 Zinc-binding domain of Paramyxoviridae V protein HypA PF01155.19 CBY08823.1 - 0.014 15.4 15.1 1.7 8.7 1.6 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HC_2 PF13913.6 CBY08823.1 - 0.02 14.8 3.3 0.17 11.8 0.4 5.7 6 0 0 6 6 6 0 zinc-finger of a C2HC-type ADK_lid PF05191.14 CBY08823.1 - 0.07 13.1 15.1 0.69 9.9 0.0 4.3 3 2 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 CBY08823.1 - 0.15 12.2 26.1 3.5 7.8 2.6 4.9 1 1 5 6 6 6 0 Zinc ribbon domain OSTMP1 PF09777.9 CBY08823.1 - 0.22 10.9 5.2 0.58 9.5 1.2 2.0 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF2256 PF10013.9 CBY08823.1 - 0.27 11.4 16.8 7.6 6.7 0.1 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-AN1 PF01428.16 CBY08823.1 - 0.28 11.4 31.4 14 5.9 0.1 6.2 4 2 2 6 6 6 0 AN1-like Zinc finger zf-C2HE PF16278.5 CBY08823.1 - 0.98 9.9 38.8 0.63 10.5 6.5 6.0 1 1 5 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 CBY08823.1 - 0.99 9.4 16.6 2.2 8.2 0.2 5.2 6 0 0 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain RNA_POL_M_15KD PF02150.16 CBY08823.1 - 1.6 8.6 12.7 15 5.6 0.1 4.7 6 0 0 6 6 5 0 RNA polymerases M/15 Kd subunit zf-RING_7 PF02591.15 CBY08823.1 - 2.9 8.1 12.8 33 4.8 0.1 4.8 5 0 0 5 5 5 0 C4-type zinc ribbon domain XPA_N PF01286.18 CBY08823.1 - 3.2 7.9 24.1 7.9 6.6 0.1 5.5 6 0 0 6 6 6 0 XPA protein N-terminal Cript PF10235.9 CBY08823.1 - 3.4 8.3 18.9 4.1 8.0 0.8 3.9 1 1 3 4 4 4 0 Microtubule-associated protein CRIPT zf-BED PF02892.15 CBY08823.1 - 3.8 7.6 33.5 3.1 7.9 0.3 5.9 1 1 3 4 4 4 0 BED zinc finger LIM PF00412.22 CBY08823.1 - 5.6 7.3 24.6 21 5.4 5.6 5.1 2 1 2 5 5 5 0 LIM domain zf-RING_2 PF13639.6 CBY08824.1 - 7.2e-07 29.4 10.6 7.2e-07 29.4 10.6 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY08824.1 - 3.8e-06 26.7 9.3 7.5e-06 25.7 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY08824.1 - 6.8e-05 22.8 11.0 6.8e-05 22.8 11.0 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBY08824.1 - 0.00053 20.0 4.9 0.0012 18.8 4.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CBY08824.1 - 0.0018 18.0 9.6 0.0039 17.0 9.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain EF_TS PF00889.19 CBY08824.1 - 0.0019 17.9 1.6 2 8.0 1.5 2.5 2 0 0 2 2 2 2 Elongation factor TS zf-C3HC4 PF00097.25 CBY08824.1 - 0.0022 17.9 11.3 0.0022 17.9 11.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY08824.1 - 0.0034 17.4 6.0 0.0034 17.4 6.0 2.2 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY08824.1 - 0.0058 16.5 10.3 0.021 14.7 10.4 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 DUF4472 PF14739.6 CBY08824.1 - 0.0084 16.8 15.5 0.01 16.5 12.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4472) KxDL PF10241.9 CBY08824.1 - 0.011 16.0 9.9 0.29 11.4 0.0 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein Golgin_A5 PF09787.9 CBY08824.1 - 0.011 15.3 16.3 0.016 14.7 16.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CALCOCO1 PF07888.11 CBY08824.1 - 0.012 14.6 13.1 0.016 14.1 13.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-rbx1 PF12678.7 CBY08824.1 - 0.017 15.4 7.4 0.048 13.9 7.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain CENP-Q PF13094.6 CBY08824.1 - 0.023 14.9 11.8 0.039 14.1 10.9 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-C3HC4_2 PF13923.6 CBY08824.1 - 0.031 14.1 9.3 0.071 13.0 9.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COG5 PF10392.9 CBY08824.1 - 0.039 14.1 5.7 1.4 9.1 2.6 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 NPV_P10 PF05531.12 CBY08824.1 - 0.039 14.4 7.5 0.41 11.2 0.4 2.6 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 CBY08824.1 - 0.06 13.4 11.0 0.7 10.0 2.5 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TEX13 PF15186.6 CBY08824.1 - 0.067 12.9 10.1 0.098 12.3 8.6 1.8 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Tmemb_55A PF09788.9 CBY08824.1 - 0.074 12.1 4.7 0.027 13.5 1.9 1.5 1 1 0 1 1 1 0 Transmembrane protein 55A zf-RING_10 PF16685.5 CBY08824.1 - 0.075 13.2 5.6 0.26 11.5 5.6 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 Laminin_I PF06008.14 CBY08824.1 - 0.15 11.8 16.0 0.22 11.2 13.8 2.0 1 1 1 2 2 2 0 Laminin Domain I zf-C3HC4_4 PF15227.6 CBY08824.1 - 0.15 12.3 13.5 0.1 12.8 10.6 2.2 2 1 1 3 3 2 0 zinc finger of C3HC4-type, RING DUF3772 PF12607.8 CBY08824.1 - 0.21 11.4 1.0 0.44 10.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Exonuc_VII_L PF02601.15 CBY08824.1 - 0.25 10.9 4.2 0.31 10.6 4.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-UDP PF14569.6 CBY08824.1 - 0.26 11.4 5.5 0.65 10.1 5.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Cep57_MT_bd PF06657.13 CBY08824.1 - 0.27 11.7 14.0 1.2 9.6 3.7 3.4 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 WD40_alt PF14077.6 CBY08824.1 - 0.3 11.0 3.3 1.4 8.9 0.1 2.8 2 1 0 2 2 2 0 Alternative WD40 repeat motif Cnn_1N PF07989.11 CBY08824.1 - 0.34 11.1 19.9 0.096 12.9 13.4 2.6 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Zn_ribbon_17 PF17120.5 CBY08824.1 - 0.37 10.4 7.8 0.69 9.6 7.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type UPF0242 PF06785.11 CBY08824.1 - 0.41 10.7 18.3 1 9.5 18.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus THP2 PF09432.10 CBY08824.1 - 0.41 10.7 6.3 0.57 10.2 5.2 1.8 1 1 0 1 1 1 0 Tho complex subunit THP2 KELK PF15796.5 CBY08824.1 - 0.44 11.0 19.5 0.049 14.1 10.0 3.1 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Baculo_IE-1 PF05290.11 CBY08824.1 - 0.48 10.4 9.7 0.079 12.9 4.7 1.9 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) ATG16 PF08614.11 CBY08824.1 - 0.51 10.5 13.5 1.6 8.9 13.5 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HTH_Tnp_IS630 PF01710.16 CBY08824.1 - 0.53 10.4 8.4 1.4 9.0 2.8 2.5 1 1 1 2 2 2 0 Transposase Baculo_p24 PF05073.12 CBY08824.1 - 0.53 10.0 10.3 2.2 8.0 10.1 2.0 1 1 0 1 1 1 0 Baculovirus P24 capsid protein bZIP_1 PF00170.21 CBY08824.1 - 0.55 10.4 20.8 11 6.2 2.2 3.9 3 1 0 3 3 3 0 bZIP transcription factor V_ATPase_I PF01496.19 CBY08824.1 - 0.87 7.4 10.7 1.1 7.0 10.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CdvA PF18822.1 CBY08824.1 - 1.4 8.7 17.7 0.57 10.0 8.3 3.2 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Phage_TAC_4 PF08748.11 CBY08824.1 - 1.7 9.0 7.6 5.9 7.2 7.6 1.9 1 1 0 1 1 1 0 Phage tail assembly chaperone HAUS-augmin3 PF14932.6 CBY08824.1 - 2.2 7.8 15.3 0.76 9.3 11.7 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Het-C PF07217.11 CBY08824.1 - 2.9 6.3 8.5 4 5.9 8.5 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TACC_C PF05010.14 CBY08824.1 - 3.3 7.4 24.5 1.3 8.8 0.4 2.8 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2058 PF09831.9 CBY08824.1 - 3.5 7.8 13.9 6 7.0 13.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF883 PF05957.13 CBY08824.1 - 4.3 8.0 5.4 2.7 8.7 2.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Bap31_Bap29_C PF18035.1 CBY08824.1 - 4.6 7.3 23.1 3.7e+02 1.2 0.1 3.6 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 CBY08824.1 - 5 6.4 9.0 7.6 5.8 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 CBY08824.1 - 5.1 7.5 20.7 13 6.2 17.1 2.5 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SpoIISA_toxin PF14171.6 CBY08824.1 - 5.1 6.7 7.7 18 4.9 4.4 2.2 1 1 1 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system LMBR1 PF04791.16 CBY08824.1 - 5.4 5.8 6.7 7.3 5.4 6.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Kinesin PF00225.23 CBY08825.1 - 8.4e-87 291.2 1.2 9.1e-87 291.1 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 CBY08825.1 - 1.8e-29 101.9 1.3 3.8e-29 100.9 0.1 2.1 2 0 0 2 2 2 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 CBY08825.1 - 2.4e-20 73.0 0.0 7.8e-20 71.3 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding ERM PF00769.19 CBY08825.1 - 0.00025 21.0 14.7 0.00025 21.0 14.7 2.8 3 0 0 3 3 3 1 Ezrin/radixin/moesin family Leu_zip PF15294.6 CBY08825.1 - 3.7 7.0 22.9 0.45 10.0 18.3 1.7 2 0 0 2 2 2 0 Leucine zipper RRM_1 PF00076.22 CBY08826.1 - 7.1e-14 51.4 0.4 1.7e-09 37.4 0.0 3.5 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY08826.1 - 1.9e-05 24.6 0.0 9.8e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 CBY08826.1 - 0.042 13.7 0.0 2.7 7.9 0.0 2.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif SET_assoc PF11767.8 CBY08826.1 - 3.1 7.5 4.7 0.96 9.1 0.0 2.6 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated XisH PF08814.10 CBY08828.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 XisH protein Pyr_redox_2 PF07992.14 CBY08830.1 - 1.7e-12 47.2 0.0 2.3e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBY08830.1 - 3.8e-06 27.0 0.1 1.8e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CBY08830.1 - 4.1e-06 26.9 0.0 1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CBY08830.1 - 0.0011 19.4 0.1 0.9 10.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBY08830.1 - 0.0074 15.6 0.3 0.4 9.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 CBY08830.1 - 0.051 14.2 0.1 11 6.7 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Thi4 PF01946.17 CBY08830.1 - 0.069 12.4 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 CBY08830.1 - 0.12 12.8 0.2 12 6.4 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CBY08830.1 - 0.16 11.2 0.1 0.16 11.2 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain DUF2540 PF10802.8 CBY08830.1 - 1.6 8.9 6.8 4.6 7.4 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2540) DEAD PF00270.29 CBY08831.1 - 1.3e-16 60.8 0.0 2.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBY08831.1 - 0.00024 21.2 0.0 0.00098 19.2 0.0 1.9 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBY08831.1 - 0.0044 17.3 0.0 0.046 14.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 CBY08831.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytochrom_C PF00034.21 CBY08832.1 - 4.3e-10 40.6 0.0 5.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CBY08832.1 - 7.9e-05 22.9 2.3 0.00016 21.9 2.3 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CBY08832.1 - 0.0065 16.2 0.3 0.01 15.5 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 CBY08832.1 - 0.1 13.0 0.3 16 5.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome P460 GAD-like PF08887.11 CBY08832.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain rRNA_proc-arch PF13234.6 CBY08833.1 - 1.6e-73 248.0 2.0 2.3e-73 247.4 0.4 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CBY08833.1 - 1.4e-53 180.9 1.3 3.2e-53 179.7 1.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Helicase_C PF00271.31 CBY08833.1 - 3.2e-06 27.5 0.0 1.2e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CENP-F_leu_zip PF10473.9 CBY08833.1 - 0.014 15.4 6.2 3.3 7.7 0.0 3.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HTH_43 PF09904.9 CBY08833.1 - 0.17 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix MAPEG PF01124.18 CBY08834.1 - 2.7e-26 92.0 0.1 3.1e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 MAPEG family Kinesin PF00225.23 CBY08835.1 - 8.3e-36 123.6 1.9 5.6e-35 120.8 1.9 2.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY08835.1 - 1e-09 38.5 0.0 2.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding ASH PF15780.5 CBY08836.1 - 5.9e-13 48.9 10.1 0.0001 22.4 0.1 8.1 9 0 0 9 9 9 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CBY08836.1 - 7.6e-08 32.5 0.0 0.017 15.4 0.0 4.8 4 0 0 4 4 4 2 Transmembrane protein 131-like DUF1573 PF07610.11 CBY08836.1 - 8e-06 25.8 0.0 1.4 9.0 0.0 5.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 CBY08836.1 - 0.00055 19.7 0.0 1.4 8.8 0.0 5.0 5 0 0 5 5 5 1 MSP (Major sperm protein) domain PapD-like PF14874.6 CBY08836.1 - 0.17 12.1 0.1 17 5.6 0.0 3.8 5 0 0 5 5 5 0 Flagellar-associated PapD-like UCMA PF17085.5 CBY08836.1 - 0.3 11.1 4.1 0.75 9.8 4.1 1.6 1 0 0 1 1 1 0 Unique cartilage matrix associated protein DUF1754 PF08555.10 CBY08836.1 - 0.6 10.9 7.5 2.1 9.2 7.5 1.9 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) FSH1 PF03959.13 CBY08837.1 - 1e-46 159.3 0.1 4.4e-46 157.2 0.1 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CBY08837.1 - 0.023 14.5 0.1 0.04 13.7 0.1 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase zf-C2H2_9 PF16293.5 CBY08838.1 - 0.0032 17.3 0.2 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 CBY08838.1 - 0.0052 17.1 0.5 0.012 15.9 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CBY08838.1 - 0.061 13.8 0.3 0.25 11.9 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY08838.1 - 0.12 13.3 0.1 0.28 12.2 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger AAA_23 PF13476.6 CBY08838.1 - 0.19 12.2 5.7 0.27 11.7 5.7 1.2 1 0 0 1 1 1 0 AAA domain zf-C2H2_jaz PF12171.8 CBY08838.1 - 0.43 10.9 3.4 0.38 11.1 1.3 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LexA_DNA_bind PF01726.16 CBY08838.1 - 0.49 10.2 4.1 1.3 8.8 0.4 2.7 2 1 1 3 3 3 0 LexA DNA binding domain PBP PF01161.20 CBY08839.1 - 1.2e-07 32.1 0.0 2.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PARG_cat PF05028.14 CBY08840.1 - 1.1e-110 370.1 0.0 1.7e-110 369.5 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) MitMem_reg PF13012.6 CBY08840.1 - 0.034 14.6 0.0 0.52 10.8 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF1798 PF08807.10 CBY08840.1 - 0.035 14.3 0.2 0.089 12.9 0.2 1.7 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Pex19 PF04614.12 CBY08840.1 - 0.053 13.3 0.3 0.053 13.3 0.3 2.5 3 0 0 3 3 3 0 Pex19 protein family PARG_cat PF05028.14 CBY08841.1 - 3.6e-108 361.8 0.3 5.3e-108 361.3 0.3 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) zf-C2H2_4 PF13894.6 CBY08842.1 - 2e-09 37.5 42.5 0.0049 17.6 0.6 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY08842.1 - 7.5e-08 32.5 33.7 0.0011 19.3 0.2 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY08842.1 - 1.3e-07 31.7 43.4 0.00013 22.2 2.0 7.1 6 1 0 6 6 6 3 Zinc finger, C2H2 type FAIM1 PF06905.13 CBY08842.1 - 0.024 14.3 0.2 0.024 14.3 0.2 2.5 3 1 0 3 3 3 0 Fas apoptotic inhibitory molecule (FAIM1) zf-H2C2_5 PF13909.6 CBY08842.1 - 0.025 14.3 2.8 0.025 14.3 2.8 6.4 5 2 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 CBY08842.1 - 0.076 13.5 0.3 0.076 13.5 0.3 5.3 2 2 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 CBY08842.1 - 0.089 13.1 0.3 0.089 13.1 0.3 5.9 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CBY08842.1 - 0.32 11.0 28.9 2.4 8.2 1.7 5.5 2 1 3 5 5 5 0 BED zinc finger Spore_III_AB PF09548.10 CBY08842.1 - 0.38 10.8 3.6 0.62 10.2 3.6 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-RING_7 PF02591.15 CBY08842.1 - 6.9 7.0 11.4 1.9 8.7 0.1 3.9 4 0 0 4 4 4 0 C4-type zinc ribbon domain AAA PF00004.29 CBY08843.1 - 1.7e-44 151.5 0.0 1e-43 148.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBY08843.1 - 8.6e-11 41.6 0.1 3e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CBY08843.1 - 7e-10 38.6 0.0 1.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBY08843.1 - 8.6e-09 35.7 0.1 3.4e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBY08843.1 - 8.9e-09 35.5 0.3 4.7e-08 33.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY08843.1 - 1.4e-06 28.8 0.2 0.00081 19.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CBY08843.1 - 3.3e-05 23.2 0.2 7.7e-05 22.0 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBY08843.1 - 4.9e-05 23.1 0.0 0.00023 20.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CBY08843.1 - 0.00016 21.7 0.1 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBY08843.1 - 0.00022 21.5 0.8 0.043 14.1 0.8 2.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBY08843.1 - 0.00024 21.4 0.0 0.00079 19.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 CBY08843.1 - 0.00027 20.3 0.0 0.00084 18.6 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBY08843.1 - 0.00051 19.5 0.1 0.0012 18.2 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBY08843.1 - 0.00085 19.6 0.0 0.0025 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBY08843.1 - 0.0011 19.6 0.0 0.0094 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBY08843.1 - 0.0012 19.0 0.0 0.0037 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 CBY08843.1 - 0.0028 17.4 0.3 0.53 10.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBY08843.1 - 0.0039 16.9 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 CBY08843.1 - 0.0042 17.0 0.1 0.037 14.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 CBY08843.1 - 0.009 15.9 0.1 0.065 13.2 0.0 2.4 3 0 0 3 3 3 1 NTPase TsaE PF02367.17 CBY08843.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 CBY08843.1 - 0.016 15.1 0.8 0.13 12.1 0.0 2.4 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CBY08843.1 - 0.02 14.5 0.7 0.11 12.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 CBY08843.1 - 0.023 14.2 0.1 0.15 11.5 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CBY08843.1 - 0.027 13.7 0.0 0.08 12.2 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 CBY08843.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CBY08843.1 - 0.05 13.0 0.0 2.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein NB-ARC PF00931.22 CBY08843.1 - 0.051 12.8 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 CBY08843.1 - 0.074 12.8 0.1 0.18 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBY08843.1 - 0.076 13.4 0.1 0.22 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 CBY08843.1 - 0.093 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 CBY08843.1 - 0.12 11.7 0.8 1.1 8.5 0.0 2.5 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.27 CBY08843.1 - 0.13 12.7 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter GrpE PF01025.19 CBY08843.1 - 1 9.0 4.8 0.76 9.4 0.1 2.4 3 0 0 3 3 2 0 GrpE Pkinase PF00069.25 CBY08844.1 - 9.6e-63 212.0 0.0 1.3e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08844.1 - 3.1e-40 138.1 0.0 4.3e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GAT PF03127.14 CBY08844.1 - 5.1e-15 55.5 0.0 5.1e-15 55.5 0.0 2.5 3 0 0 3 3 3 1 GAT domain Pkinase_fungal PF17667.1 CBY08844.1 - 0.0018 17.1 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PglD_N PF17836.1 CBY08844.1 - 0.0023 18.5 0.1 0.0094 16.6 0.1 2.0 2 0 0 2 2 2 1 PglD N-terminal domain CCDC74_C PF14917.6 CBY08844.1 - 0.032 14.7 0.0 0.059 13.9 0.0 1.3 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal Kdo PF06293.14 CBY08844.1 - 0.11 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arg_decarb_HB PF17810.1 CBY08844.1 - 0.11 12.8 0.1 0.68 10.2 0.1 2.2 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain Kinase-like PF14531.6 CBY08844.1 - 0.21 10.9 0.1 35 3.6 0.0 2.8 2 1 0 2 2 2 0 Kinase-like Cytochrom_C PF00034.21 CBY08845.1 - 4.9e-12 46.8 0.1 6e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CBY08845.1 - 0.00026 21.3 4.1 0.00067 19.9 4.1 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CBY08845.1 - 0.0022 17.7 0.2 0.0062 16.2 0.1 1.7 2 0 0 2 2 2 1 Cytochrome c-550 domain Snf7 PF03357.21 CBY08846.1 - 1e-38 132.6 28.3 1e-38 132.6 28.3 1.2 1 1 0 1 1 1 1 Snf7 DUF2570 PF10828.8 CBY08846.1 - 1.1 9.1 14.9 0.049 13.5 5.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Alanine_zipper PF11839.8 CBY08848.1 - 0.00034 20.9 37.9 0.00034 20.9 37.9 7.2 4 2 2 7 7 7 1 Alanine-zipper, major outer membrane lipoprotein zf-C4H2 PF10146.9 CBY08848.1 - 0.00036 20.9 1.4 0.00036 20.9 1.4 4.6 2 1 0 2 2 2 1 Zinc finger-containing protein GIT_CC PF16559.5 CBY08848.1 - 0.0066 16.3 4.6 0.43 10.5 1.4 2.8 2 0 0 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor Glycos_transf_2 PF00535.26 CBY08849.1 - 2e-27 96.0 0.0 3.6e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY08849.1 - 3e-16 59.8 0.3 5.9e-16 58.9 0.3 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CBY08849.1 - 6.2e-07 29.0 0.0 1.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CDtoxinA PF03498.14 CBY08849.1 - 0.0029 17.2 0.4 0.0052 16.4 0.4 1.4 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 CBY08849.1 - 0.047 14.4 0.1 0.3 11.8 0.1 2.2 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like RLAN PF14401.6 CBY08849.1 - 0.18 11.4 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain 7tm_1 PF00001.21 CBY08850.1 - 1.6e-08 34.2 2.5 1.7e-08 34.1 2.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) STE3 PF02076.15 CBY08850.1 - 0.048 12.9 3.6 0.05 12.8 3.6 1.0 1 0 0 1 1 1 0 Pheromone A receptor Trypsin PF00089.26 CBY08851.1 - 1.1e-50 172.5 0.2 1.8e-50 171.8 0.2 1.3 1 0 0 1 1 1 1 Trypsin MAM PF00629.23 CBY08851.1 - 1.2e-31 109.8 17.3 2e-17 63.6 0.8 4.4 5 0 0 5 5 5 3 MAM domain, meprin/A5/mu Trypsin_2 PF13365.6 CBY08851.1 - 1.6e-05 25.8 0.0 4.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ldl_recept_a PF00057.18 CBY08851.1 - 0.00013 22.1 14.2 0.00013 22.1 14.2 3.1 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 CBY08851.1 - 0.00029 21.2 0.0 0.00065 20.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) COP-gamma_platf PF08752.10 CBY08851.1 - 0.054 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain Forkhead PF00250.18 CBY08852.1 - 1.3e-39 134.3 0.1 3.7e-39 132.9 0.0 1.8 2 0 0 2 2 2 1 Forkhead domain TetR_C_4 PF08359.11 CBY08853.1 - 0.021 14.9 3.4 0.046 13.9 3.4 1.6 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region FSA_C PF10479.9 CBY08853.1 - 0.19 9.8 13.7 0.31 9.1 13.7 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus GvpL_GvpF PF06386.11 CBY08853.1 - 2.6 7.9 5.6 4.6 7.1 5.1 1.7 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Pkinase PF00069.25 CBY08854.1 - 1.7e-26 93.2 0.0 2.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08854.1 - 3.6e-19 69.1 0.0 4.1e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY08854.1 - 0.00013 20.9 0.0 0.00015 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CBY08855.1 - 2e-56 191.3 0.0 2.7e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08855.1 - 7.7e-33 113.9 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY08855.1 - 5.9e-06 25.8 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY08855.1 - 0.0062 16.5 0.0 0.018 15.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family PsbU PF06514.11 CBY08855.1 - 0.017 15.1 0.0 11 6.1 0.0 2.8 2 1 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) Pkinase_fungal PF17667.1 CBY08855.1 - 0.028 13.2 0.0 0.061 12.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 CBY08856.1 - 2.3e-21 75.7 3.1 1.6e-09 38.2 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY08856.1 - 5.8e-10 39.3 0.0 0.0059 16.9 0.0 4.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY08856.1 - 0.01 14.9 0.0 0.035 13.1 0.0 1.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CHCH PF06747.13 CBY08857.1 - 0.0053 16.8 2.1 0.0077 16.3 2.1 1.3 1 0 0 1 1 1 1 CHCH domain Ribosomal_60s PF00428.19 CBY08857.1 - 1.2 9.8 17.4 0.25 12.0 2.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2076 PF09849.9 CBY08857.1 - 3 7.8 21.1 14 5.7 20.8 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Selenoprotein_S PF06936.11 CBY08858.1 - 6.7e-12 45.6 8.5 8.4e-12 45.3 8.5 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) Selenoprotein_S PF06936.11 CBY08859.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) G-patch PF01585.23 CBY08860.1 - 7.9e-15 54.5 1.0 2.4e-14 52.9 1.0 1.9 1 0 0 1 1 1 1 G-patch domain DND1_DSRM PF14709.7 CBY08860.1 - 1.3e-09 38.2 0.6 2.2e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 CBY08860.1 - 2.3e-09 37.8 0.0 5.7e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif RSRP PF17069.5 CBY08860.1 - 0.00033 20.3 48.7 0.00033 20.3 48.7 2.1 1 1 1 2 2 2 1 Arginine/Serine-Rich protein 1 G-patch_2 PF12656.7 CBY08860.1 - 0.00047 20.2 0.7 0.00047 20.2 0.7 3.4 2 1 0 2 2 2 1 G-patch domain Macoilin PF09726.9 CBY08860.1 - 2.2 6.7 22.5 3.5 6.1 22.5 1.3 1 0 0 1 1 1 0 Macoilin family G_glu_transpept PF01019.21 CBY08862.1 - 0.0058 15.5 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glyco_transf_22 PF03901.17 CBY08863.1 - 2e-45 155.8 26.2 2.6e-45 155.4 26.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Tim17 PF02466.19 CBY08864.1 - 2.5e-18 66.5 10.2 3.1e-18 66.2 10.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Kelch_6 PF13964.6 CBY08865.1 - 0.00018 21.7 2.3 0.66 10.4 0.1 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CBY08865.1 - 0.00095 18.7 1.4 4.8 6.9 0.0 4.1 3 0 0 3 3 3 3 Kelch motif 7tm_1 PF00001.21 CBY08866.1 - 1.6e-45 155.5 16.5 2.2e-45 155.0 16.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CBY08866.1 - 2.7e-06 27.3 7.8 3.8e-06 26.9 7.8 1.2 1 0 0 1 1 1 1 Olfactory receptor TerC PF03741.16 CBY08866.1 - 7.7 6.2 8.5 10 5.8 3.3 2.8 2 1 0 2 2 2 0 Integral membrane protein TerC family 7tm_1 PF00001.21 CBY08867.1 - 4.2e-10 39.4 6.4 6.3e-07 29.0 2.1 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) TMEM215 PF15746.5 CBY08867.1 - 0.0051 16.3 0.1 0.61 9.5 0.0 2.4 2 0 0 2 2 2 2 TMEM215 family Sulf_transp PF04143.14 CBY08867.1 - 0.014 15.0 0.5 0.014 15.0 0.5 1.5 2 0 0 2 2 2 0 Sulphur transport GPR_Gpa2_C PF11970.8 CBY08867.1 - 0.072 13.2 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term EI24 PF07264.11 CBY08867.1 - 0.19 11.9 4.7 0.083 13.1 1.6 2.0 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF4349 PF14257.6 CBY08867.1 - 0.33 10.4 2.9 3.1 7.2 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) PWWP PF00855.17 CBY08868.1 - 2.5e-14 53.4 0.1 6.1e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 PWWP domain AAA_12 PF13087.6 CBY08869.1 - 2.1e-44 151.6 0.8 2.1e-44 151.6 0.8 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBY08869.1 - 7.2e-20 71.9 1.8 7.2e-20 71.9 1.8 3.1 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 CBY08869.1 - 2.7e-10 40.8 0.2 9.3e-10 39.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBY08869.1 - 1.1e-07 31.8 0.0 1.5e-05 24.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 CBY08869.1 - 0.0048 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 CBY08869.1 - 0.0057 16.7 3.6 0.024 14.7 0.5 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBY08869.1 - 0.007 16.7 0.2 0.025 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 CBY08869.1 - 0.031 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 CBY08869.1 - 0.041 14.3 0.0 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CBY08869.1 - 0.042 14.3 0.0 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CBY08869.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 CBY08870.1 - 5.3e-160 533.9 0.0 5.3e-160 533.9 0.0 2.1 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY08870.1 - 3e-139 465.8 248.9 4.1e-139 465.3 248.9 1.1 1 0 0 1 1 1 1 Myosin tail zf-H2C2_2 PF13465.6 CBY08871.1 - 8.8e-21 73.3 41.7 5.6e-08 32.9 4.8 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY08871.1 - 2.6e-17 62.2 44.4 6.8e-06 26.2 1.9 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY08871.1 - 3.8e-11 42.8 42.4 0.00071 20.2 1.5 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY08871.1 - 9.2e-11 41.7 29.0 0.036 14.4 0.2 5.4 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY08871.1 - 9.3e-08 32.2 31.4 0.018 15.4 0.2 5.4 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CBY08871.1 - 0.002 18.6 26.9 0.43 11.1 0.2 5.7 2 1 3 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 CBY08871.1 - 0.018 15.4 27.7 5.1 7.5 0.7 5.3 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF2180 PF09947.9 CBY08871.1 - 0.058 13.4 0.5 0.058 13.4 0.5 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_6 PF13912.6 CBY08871.1 - 0.9 9.6 41.1 0.29 11.2 3.3 5.8 6 1 0 6 6 6 0 C2H2-type zinc finger PHF5 PF03660.14 CBY08871.1 - 1.3 9.2 6.9 0.63 10.3 3.3 2.2 2 1 0 2 2 2 0 PHF5-like protein zf-C2H2_jaz PF12171.8 CBY08872.1 - 1.5e-06 28.3 6.4 0.0086 16.3 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY08872.1 - 0.00082 19.7 2.4 0.077 13.3 0.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CBY08872.1 - 0.0052 17.1 7.6 0.69 10.4 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY08872.1 - 0.05 14.5 12.9 0.23 12.4 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger OrsD PF12013.8 CBY08872.1 - 0.06 13.8 4.2 0.79 10.2 0.1 3.0 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-met2 PF12907.7 CBY08872.1 - 0.37 11.0 2.9 4.2 7.6 0.0 3.2 3 0 0 3 3 3 0 Zinc-binding Atx10homo_assoc PF09759.9 CBY08873.1 - 0.038 14.0 0.1 0.21 11.6 0.1 2.4 1 1 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain PPV_E1_N PF00524.18 CBY08873.1 - 0.23 11.9 1.9 2.4 8.6 0.3 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain WD40 PF00400.32 CBY08874.1 - 6.5e-38 128.1 17.9 7.5e-09 36.1 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CBY08874.1 - 4.2e-33 114.3 2.1 7.2e-33 113.6 2.1 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CBY08874.1 - 5.5e-12 45.8 0.0 9.6e-05 22.6 0.0 4.5 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY08874.1 - 0.0028 17.6 0.0 0.09 12.6 0.0 2.7 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CBY08874.1 - 0.12 11.0 0.0 4.1 5.9 0.0 2.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 MBOAT PF03062.19 CBY08875.1 - 5.2e-11 42.5 16.4 6.9e-10 38.8 1.5 2.9 2 1 0 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family PARP PF00644.20 CBY08875.1 - 2.1e-09 37.3 0.1 4.7e-09 36.1 0.1 1.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 CBY08875.1 - 5.1e-08 33.1 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 ARTD15 N-terminal domain Exotox-A_cataly PF09009.10 CBY08875.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic Mago_nashi PF02792.14 CBY08876.1 - 1.6e-77 258.5 0.2 1.8e-77 258.3 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DCP2 PF05026.13 CBY08878.1 - 7.6e-26 90.3 2.4 8.3e-26 90.1 0.6 2.0 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 CBY08878.1 - 1.7e-17 63.7 0.0 3.4e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain MARVEL PF01284.23 CBY08879.1 - 4.8e-05 23.4 10.8 6.6e-05 23.0 10.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Ribosomal_L27A PF00828.19 CBY08880.1 - 8.6e-09 36.1 0.0 1.7e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4953 PF16313.5 CBY08880.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Met-zincin IBR PF01485.21 CBY08881.1 - 2.1e-16 59.9 47.3 1.4e-09 38.0 5.4 5.0 4 2 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 CBY08881.1 - 0.0018 18.1 0.6 0.0018 18.1 0.6 5.4 3 1 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Vps39_1 PF10366.9 CBY08881.1 - 0.017 15.4 0.5 0.044 14.1 0.5 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 zf-C3HC4 PF00097.25 CBY08881.1 - 0.64 9.9 36.9 0.034 14.0 7.6 5.4 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf_UBZ PF18439.1 CBY08881.1 - 9.4 5.9 8.7 8.1 6.1 0.3 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger JAB PF01398.21 CBY08882.1 - 2.4e-28 98.5 0.2 4.6e-28 97.6 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 CBY08882.1 - 8e-14 52.3 0.2 1.8e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 CBY08882.1 - 0.00026 20.7 0.1 0.00043 20.1 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CBY08882.1 - 0.053 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF4471 PF14740.6 CBY08883.1 - 2.2e-58 197.9 1.9 2.9e-58 197.5 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 CBY08883.1 - 4.8e-24 84.4 0.0 8.2e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) DUF4471 PF14740.6 CBY08884.1 - 2.7e-15 56.4 1.1 2.9e-15 56.3 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) VPS13_mid_rpt PF16910.5 CBY08885.1 - 5.9e-28 97.9 1.2 9e-24 84.2 0.1 2.9 3 1 0 3 3 3 2 Repeating coiled region of VPS13 VPS13 PF16908.5 CBY08885.1 - 4.8e-16 59.3 11.9 2.2e-13 50.6 1.9 3.7 3 1 1 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CBY08886.1 - 8.1e-61 205.8 0.5 5.1e-56 190.0 0.0 3.3 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 CBY08886.1 - 5.6e-15 55.6 2.5 4e-09 36.5 0.0 3.9 3 1 1 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal XPA_C PF05181.12 CBY08887.1 - 2.4e-19 69.0 0.8 4.5e-19 68.1 0.8 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CBY08887.1 - 5.3e-08 32.8 7.1 7.7e-08 32.2 7.1 1.3 1 0 0 1 1 1 1 XPA protein N-terminal ZZ PF00569.17 CBY08887.1 - 3.3 7.6 7.5 2 8.3 1.5 2.2 1 1 1 2 2 2 0 Zinc finger, ZZ type adh_short PF00106.25 CBY08888.1 - 1.2e-33 116.2 0.6 2.1e-33 115.4 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase MaoC_dehydratas PF01575.19 CBY08888.1 - 2.1e-28 98.3 0.0 4.3e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.6 CBY08888.1 - 3.9e-27 95.3 0.1 7e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 CBY08888.1 - 7e-23 81.0 1.8 8.3e-23 80.8 0.7 1.7 2 0 0 2 2 2 1 SCP-2 sterol transfer family KR PF08659.10 CBY08888.1 - 5.6e-10 39.4 0.1 1.2e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.6 CBY08888.1 - 1.5e-09 38.0 0.0 1.2e-07 31.9 0.0 2.6 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.6 CBY08888.1 - 7.2e-07 29.5 0.1 1.4e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Pkinase PF00069.25 CBY08889.1 - 5.6e-14 52.1 0.1 9.9e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08889.1 - 7.8e-09 35.2 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_S64 PF08192.11 CBY08889.1 - 0.0012 17.4 3.8 0.0016 17.0 3.8 1.2 1 0 0 1 1 1 1 Peptidase family S64 Cwf_Cwc_15 PF04889.12 CBY08889.1 - 0.32 10.7 8.4 0.44 10.2 8.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NAP PF00956.18 CBY08890.1 - 1.4e-25 90.0 11.3 2.7e-21 76.0 3.6 2.9 1 1 2 3 3 3 2 Nucleosome assembly protein (NAP) PIP5K PF01504.18 CBY08891.1 - 3.8e-40 137.8 3.5 1.1e-32 113.3 0.4 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CBY08891.1 - 3.4e-19 68.9 0.4 7.3e-19 67.7 0.4 1.5 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CBY08891.1 - 9.8e-13 48.0 14.1 4.3e-12 46.0 14.1 2.1 1 0 0 1 1 1 1 FYVE zinc finger ACAS_N PF16177.5 CBY08891.1 - 0.023 14.6 0.7 0.072 13.0 0.7 1.9 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus IBR PF01485.21 CBY08891.1 - 0.046 14.0 6.8 0.19 12.0 6.8 2.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain SNARE PF05739.19 CBY08893.1 - 6.7e-13 48.4 0.6 1.6e-12 47.2 0.6 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CBY08893.1 - 0.00017 21.3 2.8 0.00017 21.3 2.8 3.0 2 1 1 3 3 3 1 Syntaxin T3SS_needle_E PF08988.10 CBY08893.1 - 0.0034 17.5 0.1 0.012 15.7 0.1 1.9 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle DUF3510 PF12022.8 CBY08893.1 - 0.012 16.0 6.7 0.062 13.7 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) MCPsignal PF00015.21 CBY08893.1 - 0.022 14.6 0.7 0.032 14.1 0.1 1.6 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ETRAMP PF09716.10 CBY08893.1 - 0.059 13.4 1.3 1.8 8.7 0.2 2.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FlaC_arch PF05377.11 CBY08893.1 - 0.08 13.4 2.3 3.6 8.1 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3089 PF11288.8 CBY08893.1 - 0.11 12.1 0.2 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) TMPIT PF07851.13 CBY08893.1 - 0.16 11.2 8.4 0.02 14.2 3.4 1.7 1 1 1 2 2 2 0 TMPIT-like protein DUF489 PF04356.12 CBY08893.1 - 0.35 10.9 0.0 0.35 10.9 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF489) DUF2779 PF11074.8 CBY08893.1 - 3.9 8.0 9.8 7e+02 0.7 9.8 2.8 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) DOT1 PF08123.13 CBY08894.1 - 3.4e-06 26.8 0.6 5.9e-06 26.0 0.6 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 CBY08894.1 - 3.4e-05 23.7 0.1 5.5e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBY08894.1 - 0.0034 17.3 0.3 0.0053 16.7 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 CBY08894.1 - 0.0042 16.3 0.1 0.0059 15.8 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.6 CBY08894.1 - 0.0077 16.9 0.0 0.02 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBY08894.1 - 0.035 13.7 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF43 PF01861.16 CBY08894.1 - 0.035 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 CBY08894.1 - 0.11 13.2 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SH3_1 PF00018.28 CBY08895.1 - 1e-05 25.0 0.2 2.8e-05 23.6 0.2 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY08895.1 - 0.0058 16.3 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CBY08895.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain IRK_C PF17655.1 CBY08896.1 - 8.8e-65 217.5 0.0 1.1e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY08896.1 - 1.5e-43 148.0 3.0 2.2e-43 147.5 3.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY08896.1 - 4.2e-05 23.4 2.7 9.4e-05 22.3 2.7 1.6 1 1 0 1 1 1 1 Ion channel DUF2182 PF09948.9 CBY08896.1 - 0.16 11.8 1.0 0.24 11.2 1.0 1.4 1 1 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) RhoGAP PF00620.27 CBY08897.1 - 6.6e-27 94.2 0.2 2e-26 92.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Connexin PF00029.19 CBY08898.1 - 2.7e-15 56.8 0.8 3.2e-15 56.5 0.8 1.1 1 0 0 1 1 1 1 Connexin ALG11_N PF15924.5 CBY08898.1 - 0.0073 16.4 0.5 0.01 15.9 0.5 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus WD40 PF00400.32 CBY08900.1 - 1e-11 45.2 5.9 0.00018 22.2 0.6 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY08900.1 - 1.3e-05 25.4 0.6 0.65 10.3 0.1 4.6 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CBY08900.1 - 0.027 13.4 0.2 0.15 10.9 0.0 2.3 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain G8 PF10162.9 CBY08901.1 - 4.3e-51 172.1 0.1 3.5e-29 101.4 0.0 2.8 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 CBY08901.1 - 1.6e-38 130.7 40.4 1.5e-09 37.8 1.6 7.8 8 0 0 8 8 8 6 IPT/TIG domain Mucin2_WxxW PF13330.6 CBY08901.1 - 2e-10 41.3 0.4 6.4e-10 39.7 0.4 2.0 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region Beta_helix PF13229.6 CBY08901.1 - 7.9e-10 38.8 20.7 6e-05 23.0 0.1 5.0 3 1 0 4 4 4 3 Right handed beta helix region DUF1348 PF07080.11 CBY08901.1 - 0.023 14.6 0.1 0.43 10.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) Trehalase PF01204.18 CBY08902.1 - 1e-118 397.4 1.6 1.2e-118 397.2 1.6 1.0 1 0 0 1 1 1 1 Trehalase Trehalase PF01204.18 CBY08903.1 - 8.9e-113 377.8 3.4 6.2e-112 375.0 3.4 1.8 1 1 0 1 1 1 1 Trehalase Na_Ca_ex PF01699.24 CBY08904.1 - 1.5e-30 106.2 16.9 1.5e-30 106.2 16.9 1.3 2 0 0 2 2 2 1 Sodium/calcium exchanger protein DPM3 PF08285.11 CBY08904.1 - 2.8 8.2 6.9 7.3 6.9 1.0 2.6 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Na_Ca_ex PF01699.24 CBY08905.1 - 1e-11 45.0 1.2 2.7e-11 43.6 0.3 1.8 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Glyco_hydro_31 PF01055.26 CBY08906.1 - 1.2e-139 466.4 6.5 1.7e-139 465.8 6.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CBY08906.1 - 1.9e-19 69.7 1.6 6.3e-18 64.9 0.0 3.5 4 0 0 4 4 4 1 Galactose mutarotase-like DUF5110 PF17137.4 CBY08906.1 - 3.5e-05 24.0 0.5 8.8e-05 22.7 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Glyco_transf_8 PF01501.20 CBY08907.1 - 4.2e-21 75.7 0.0 2e-19 70.2 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CBY08907.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 CBY08907.1 - 0.15 12.0 0.4 0.31 11.0 0.1 1.6 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase CNH PF00780.22 CBY08908.1 - 2.8e-12 46.8 0.0 6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 CNH domain FPP PF05911.11 CBY08908.1 - 0.0018 16.5 25.9 0.0018 16.5 25.9 5.2 1 1 4 5 5 5 1 Filament-like plant protein, long coiled-coil FliJ PF02050.16 CBY08908.1 - 0.0056 16.9 14.0 0.0056 16.9 14.0 10.7 2 2 9 12 12 12 2 Flagellar FliJ protein Halo_GVPC PF05465.13 CBY08908.1 - 0.0062 16.8 0.5 10 6.5 0.0 3.7 3 0 0 3 3 3 2 Halobacterial gas vesicle protein C (GVPC) repeat PH PF00169.29 CBY08908.1 - 0.0071 16.8 0.0 0.041 14.4 0.0 2.4 1 0 0 1 1 1 1 PH domain HIP1_clath_bdg PF16515.5 CBY08908.1 - 0.0082 16.7 10.4 0.0082 16.7 10.4 12.5 2 2 9 12 12 12 2 Clathrin-binding domain of Huntingtin-interacting protein 1 Cnn_1N PF07989.11 CBY08908.1 - 0.06 13.5 0.1 0.06 13.5 0.1 14.1 6 2 7 14 14 14 0 Centrosomin N-terminal motif 1 RabGAP-TBC PF00566.18 CBY08909.1 - 2.5e-42 145.0 5.3 2.5e-42 145.0 5.3 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Usg PF06233.12 CBY08909.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Usg-like family ASXH PF13919.6 CBY08909.1 - 0.046 13.7 2.7 2.3 8.2 0.0 3.2 3 0 0 3 3 3 0 Asx homology domain 7tm_2 PF00002.24 CBY08910.1 - 1.6e-52 178.2 9.5 2.5e-52 177.6 9.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 CBY08910.1 - 6.1e-07 28.9 8.9 1.3e-06 27.8 8.9 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor LRRC37AB_C PF14914.6 CBY08910.1 - 0.12 12.3 0.7 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF3671 PF12420.8 CBY08910.1 - 2.5 8.2 7.4 3.2 7.8 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function Snapin_Pallidin PF14712.6 CBY08911.1 - 0.057 13.8 0.5 0.26 11.7 0.0 2.3 3 1 0 3 3 3 0 Snapin/Pallidin U3_assoc_6 PF08640.11 CBY08912.1 - 0.032 14.3 2.1 0.25 11.4 1.6 2.4 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 SCAPER_N PF16501.5 CBY08912.1 - 0.04 13.9 4.6 0.05 13.6 2.7 2.1 1 1 1 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum DUF523 PF04463.12 CBY08912.1 - 0.11 12.6 1.1 0.21 11.6 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF523) DUF3510 PF12022.8 CBY08912.1 - 4.6 7.7 8.0 2 8.8 3.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3510) CDC27 PF09507.10 CBY08913.1 - 2.6e-11 43.6 54.0 1.7e-10 40.9 54.0 1.9 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Uso1_p115_head PF04869.14 CBY08914.1 - 4.2e-20 72.1 0.5 1.2e-19 70.6 0.0 2.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region MMR_HSR1 PF01926.23 CBY08914.1 - 4.7e-14 52.5 0.0 2.6e-13 50.0 0.0 2.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arm_vescicular PF18770.1 CBY08914.1 - 6.9e-11 41.9 0.0 1.8e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor FeoB_N PF02421.18 CBY08914.1 - 1.4e-06 27.9 1.2 3.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Uso1_p115_C PF04871.13 CBY08914.1 - 2.1e-06 28.1 22.6 2.1e-06 28.1 22.6 6.6 1 1 3 4 4 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Dynamin_N PF00350.23 CBY08914.1 - 0.0001 22.4 0.1 0.0001 22.4 0.1 3.8 3 2 0 3 3 2 1 Dynamin family Roc PF08477.13 CBY08914.1 - 0.0063 16.7 0.0 0.96 9.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CBY08914.1 - 0.018 14.6 1.2 0.34 10.4 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Arf PF00025.21 CBY08914.1 - 0.073 12.5 9.7 0.14 11.6 0.0 4.0 4 0 0 4 4 4 0 ADP-ribosylation factor family ABC_tran PF00005.27 CBY08914.1 - 0.38 11.2 0.0 0.38 11.2 0.0 4.7 3 2 0 3 3 2 0 ABC transporter DUF4806 PF16064.5 CBY08914.1 - 0.48 10.7 2.7 5.3 7.4 0.2 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) RsgA_GTPase PF03193.16 CBY08914.1 - 1 9.3 8.7 1.3 9.0 0.0 4.1 4 0 0 4 4 4 0 RsgA GTPase DUF948 PF06103.11 CBY08914.1 - 7.5 6.9 15.1 0.053 13.8 1.8 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Leucyl-specific PF14795.6 CBY08914.1 - 9.6 6.4 6.9 1.3 9.1 0.2 3.1 3 0 0 3 3 3 0 Leucine-tRNA synthetase-specific domain Calici_MSP PF05752.11 CBY08915.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF3539 PF12058.8 CBY08915.1 - 0.17 12.1 0.0 1.4 9.1 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3539) Avl9 PF09794.9 CBY08916.1 - 2.2e-32 112.2 0.0 2.7e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 QslA_E PF18226.1 CBY08916.1 - 0.13 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 LasR-specific antiactivator QslA chain E Avl9 PF09794.9 CBY08917.1 - 6.5e-54 183.1 0.0 7.8e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 CBY08917.1 - 1.2e-05 25.0 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 CBY08917.1 - 3.1e-05 24.5 0.0 4.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking His_Phos_1 PF00300.22 CBY08918.1 - 4.7e-22 78.6 0.0 7.3e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Glutaredoxin PF00462.24 CBY08919.1 - 7.9e-19 67.6 0.0 9.4e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 CBY08919.1 - 0.00049 20.5 0.0 0.00053 20.3 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 CBY08919.1 - 0.00088 19.3 0.0 0.0014 18.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.6 CBY08919.1 - 0.0042 17.5 0.0 0.005 17.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 CBY08919.1 - 0.023 15.2 0.1 0.043 14.3 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain HhH-GPD PF00730.25 CBY08920.1 - 1.2e-20 74.0 0.0 1.9e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CBY08920.1 - 2.4e-07 30.3 0.0 7.8e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif DAZAP2 PF11029.8 CBY08921.1 - 3.5e-33 115.3 29.2 3.5e-33 115.3 29.2 2.1 1 1 1 2 2 2 1 DAZ associated protein 2 (DAZAP2) WD40 PF00400.32 CBY08922.1 - 2.1e-35 120.1 11.2 3.5e-06 27.6 0.1 10.5 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY08922.1 - 3.3e-15 56.2 8.4 0.0067 16.7 0.0 7.2 3 2 5 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CBY08922.1 - 8.8e-08 32.4 1.1 1.9e-07 31.4 1.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 CBY08922.1 - 9.8e-06 25.1 0.5 0.027 13.8 0.0 3.2 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CBY08922.1 - 0.0036 16.0 1.4 0.11 11.1 0.0 3.6 3 1 2 5 5 5 1 Nucleoporin Nup120/160 MRP-S34 PF16053.5 CBY08923.1 - 5.3e-10 39.0 0.0 7e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S34 dsrm PF00035.26 CBY08924.1 - 2.8e-16 60.0 3.1 1e-06 29.3 0.1 3.7 3 0 0 3 3 3 2 Double-stranded RNA binding motif R3H PF01424.22 CBY08924.1 - 5.5e-09 35.9 0.0 1.8e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 CBY08924.1 - 0.0011 18.8 3.7 0.002 18.0 2.4 2.0 2 0 0 2 2 2 1 G-patch domain ER PF01133.17 CBY08925.1 - 8.8e-42 141.1 4.6 9.7e-42 141.0 4.6 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary UAA PF08449.11 CBY08926.1 - 1.1e-58 198.9 14.9 1.3e-58 198.7 14.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBY08926.1 - 2.2e-14 53.8 18.2 8.6e-13 48.6 5.6 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CBY08926.1 - 4.1e-12 46.0 6.8 1.1e-11 44.6 6.8 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family Internalin_N PF12354.8 CBY08926.1 - 0.025 14.6 0.3 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal SLC35F PF06027.12 CBY08926.1 - 0.029 13.9 7.0 0.06 12.8 7.0 1.6 1 1 0 1 1 1 0 Solute carrier family 35 SAP18 PF06487.12 CBY08927.1 - 1.1e-38 132.5 0.0 1.8e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) zf-UBP PF02148.19 CBY08928.1 - 2.7e-09 37.2 8.1 2.7e-09 37.2 8.1 1.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-B_box PF00643.24 CBY08928.1 - 2.7 8.2 12.0 0.12 12.6 6.5 1.7 2 0 0 2 2 2 0 B-box zinc finger Zona_pellucida PF00100.23 CBY08929.1 - 3.4e-15 56.5 0.2 4.5e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 CBY08930.1 - 1.4e-20 74.2 2.4 1.9e-20 73.8 2.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DEAD PF00270.29 CBY08931.1 - 7.1e-26 91.0 0.0 1.6e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY08931.1 - 3.5e-25 88.5 0.0 8e-24 84.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FKBP_C PF00254.28 CBY08932.1 - 5.5e-36 122.8 0.0 6.9e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sulfotransfer_4 PF17784.1 CBY08934.1 - 2.2e-51 174.7 0.1 2.6e-51 174.5 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain zf-C2H2_4 PF13894.6 CBY08935.1 - 2.7e-09 37.1 31.3 0.0034 18.1 0.3 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY08935.1 - 2.5e-05 24.5 32.7 0.0056 17.1 0.3 5.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CBY08935.1 - 9.6e-05 22.1 0.8 0.0069 16.1 0.1 3.5 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 CBY08935.1 - 0.021 15.5 1.6 0.021 15.5 1.6 3.9 3 1 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CBY08935.1 - 0.027 14.5 2.8 0.027 14.5 2.8 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 CBY08935.1 - 0.39 10.3 10.1 2.7 7.6 0.0 4.6 4 0 0 4 4 4 0 TFIIB zinc-binding zf-met PF12874.7 CBY08935.1 - 8.6 6.9 10.0 4 8.0 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type KfrA_N PF11740.8 CBY08936.1 - 0.015 16.0 0.0 0.023 15.4 0.0 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RPN1_C PF18051.1 CBY08936.1 - 0.1 12.6 0.3 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal Proteasome PF00227.26 CBY08939.1 - 4.4e-27 94.8 0.0 5.3e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RelB_N PF18506.1 CBY08939.1 - 0.067 13.0 1.7 0.15 11.9 1.7 1.5 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain Pro_isomerase PF00160.21 CBY08940.1 - 1.9e-47 161.5 0.2 2.1e-47 161.3 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FSA_C PF10479.9 CBY08942.1 - 1.9e-49 168.5 13.9 8.6e-18 63.8 0.1 4.5 3 1 1 5 5 5 4 Fragile site-associated protein C-terminus HTH_7 PF02796.15 CBY08943.1 - 0.076 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Syndecan PF01034.20 CBY08945.1 - 0.0003 20.6 0.1 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 Syndecan domain Ig_2 PF13895.6 CBY08945.1 - 0.00053 20.3 0.1 0.068 13.5 0.1 2.6 2 0 0 2 2 2 1 Immunoglobulin domain TMEM154 PF15102.6 CBY08945.1 - 0.099 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 CBY08945.1 - 0.14 13.1 0.0 0.35 11.8 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TGF_beta PF00019.20 CBY08948.1 - 0.00017 22.5 1.5 0.0041 18.1 1.5 2.6 1 1 0 1 1 1 1 Transforming growth factor beta like domain ArfGap PF01412.18 CBY08949.1 - 1.5 8.9 5.1 0.34 11.0 0.8 2.1 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Sec62 PF03839.16 CBY08950.1 - 8.9e-55 185.5 1.4 1.2e-54 185.1 1.4 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 APC1_C PF18122.1 CBY08951.1 - 0.13 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF3945 PF13101.6 CBY08951.1 - 0.37 10.5 4.6 3.7 7.4 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3945) tRNA-synt_2d PF01409.20 CBY08952.1 - 8.3e-48 163.0 2.8 4.1e-27 95.2 0.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CBY08952.1 - 1.4e-10 41.4 0.0 2.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Ribosomal_L30 PF00327.20 CBY08954.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e DUF3456 PF11938.8 CBY08955.1 - 0.043 14.3 0.1 0.069 13.7 0.1 1.3 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP zf-Nse PF11789.8 CBY08956.1 - 3.1e-09 36.5 0.3 4.5e-09 36.0 0.3 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CBY08956.1 - 0.024 14.6 0.1 0.044 13.8 0.1 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.20 CBY08956.1 - 0.026 14.2 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger IBR PF01485.21 CBY08956.1 - 0.087 13.1 1.3 0.11 12.7 0.2 1.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain IFNGR1 PF07140.11 CBY08956.1 - 0.091 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) Zona_pellucida PF00100.23 CBY08957.1 - 3.8e-23 82.6 0.0 4.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3377 PF11857.8 CBY08957.1 - 0.093 12.7 1.3 0.23 11.4 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Wzy_C PF04932.15 CBY08958.1 - 0.061 13.0 4.0 0.13 11.9 4.0 1.7 1 1 0 1 1 1 0 O-Antigen ligase YwiC PF14256.6 CBY08958.1 - 0.086 13.2 3.0 0.096 13.0 2.2 1.4 1 1 0 1 1 1 0 YwiC-like protein Claudin_2 PF13903.6 CBY08958.1 - 0.24 11.1 6.7 0.42 10.3 6.7 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction GPI2 PF06432.11 CBY08958.1 - 0.34 10.3 6.5 0.49 9.8 6.5 1.3 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4878 PF12870.7 CBY08960.1 - 0.0092 16.3 3.0 0.02 15.2 3.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4878) Ima1_N PF09779.9 CBY08961.1 - 1.4e-22 81.0 3.6 2.5e-22 80.2 3.6 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain MSC PF09402.10 CBY08961.1 - 0.065 12.7 0.9 11 5.3 0.1 2.5 3 0 0 3 3 3 0 Man1-Src1p-C-terminal domain UL42 PF17638.2 CBY08961.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 HCMV UL42 Synuclein PF01387.17 CBY08962.1 - 0.16 12.2 1.6 1.7 8.8 0.1 2.4 2 1 0 2 2 2 0 Synuclein Glycos_transf_2 PF00535.26 CBY08963.1 - 3e-24 85.7 0.0 3.6e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBY08963.1 - 3.9e-10 40.0 0.0 5.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CBY08963.1 - 4e-09 36.4 0.0 5.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CBY08963.1 - 0.0036 17.8 0.0 0.0069 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 CAP59_mtransfer PF11735.8 CBY08963.1 - 0.035 13.8 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 NTF2 PF02136.20 CBY08965.1 - 3.2e-26 92.3 0.0 3.6e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 CBY08965.1 - 0.03 14.7 0.0 0.037 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Shugoshin_C PF07557.11 CBY08966.1 - 1e-09 38.0 3.9 1e-09 38.0 3.9 3.2 2 0 0 2 2 2 1 Shugoshin C terminus CSD PF00313.22 CBY08967.1 - 7.8e-08 32.1 0.1 1.3e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Nnf1 PF03980.14 CBY08968.1 - 3 8.2 6.6 12 6.3 4.0 2.5 2 1 0 2 2 2 0 Nnf1 Histone_H2A_C PF16211.5 CBY08972.1 - 4.4e-16 58.3 0.9 4.4e-16 58.3 0.9 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CBY08972.1 - 5e-15 56.0 0.0 6.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY08972.1 - 3.4e-06 27.2 0.0 5.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY08973.1 - 7.5e-17 61.9 0.7 9.9e-17 61.5 0.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY08973.1 - 0.00043 20.5 0.9 0.00093 19.4 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY08974.1 - 1.2e-50 171.3 2.0 1.3e-50 171.1 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY08974.1 - 0.00017 21.6 0.5 0.00026 21.1 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY08974.1 - 0.00078 20.0 1.4 0.00086 19.9 1.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY08974.1 - 0.0008 19.7 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY08974.1 - 0.032 14.5 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sirohm_synth_M PF14824.6 CBY08974.1 - 1.3 8.6 3.8 4.7 6.8 0.4 2.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central FA_hydroxylase PF04116.13 CBY08975.1 - 2.6e-23 82.8 13.9 6.6e-23 81.5 13.9 1.7 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily EMC1_C PF07774.13 CBY08975.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 ER membrane protein complex subunit 1, C-terminal Trypsin PF00089.26 CBY08977.1 - 2.1e-26 93.1 0.4 2.5e-26 92.9 0.4 1.0 1 0 0 1 1 1 1 Trypsin Glyco_hydro_35 PF01301.19 CBY08981.1 - 3.5e-99 332.4 0.4 4.6e-99 332.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY08981.1 - 3.1e-10 40.0 0.6 6.9e-09 35.5 0.1 2.9 2 1 0 2 2 2 1 Beta-galactosidase MH1 PF03165.16 CBY08982.1 - 0.25 11.6 7.4 4 7.7 0.0 4.2 4 0 0 4 4 4 0 MH1 domain Connexin PF00029.19 CBY08982.1 - 0.62 9.8 10.6 0.033 13.9 4.1 2.0 2 0 0 2 2 2 0 Connexin ORC_WH_C PF18137.1 CBY08982.1 - 1.8 8.6 12.3 2.3 8.3 0.1 2.8 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal RNA_pol_Rpc4 PF05132.14 CBY08982.1 - 4 7.8 9.6 1.5 9.2 4.4 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 zf-C3HC4_2 PF13923.6 CBY08983.1 - 1.6e-10 40.6 25.5 8.4e-08 31.9 8.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY08983.1 - 1.1e-09 38.4 27.4 1.3e-08 35.0 8.9 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 CBY08983.1 - 1.2e-09 37.8 27.5 8.6e-08 31.9 9.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY08983.1 - 1.4e-09 37.7 24.4 7.8e-06 25.7 8.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY08983.1 - 8.3e-09 35.3 22.1 1.5e-05 24.9 6.4 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 CBY08983.1 - 2.8e-08 33.6 26.9 0.00016 21.6 9.2 2.4 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY08983.1 - 0.00041 20.1 26.2 0.092 12.6 4.1 3.5 2 1 1 3 3 3 3 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CBY08983.1 - 0.00046 20.3 11.7 0.00046 20.3 11.7 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBY08983.1 - 0.0012 19.1 5.8 0.0012 19.1 5.8 2.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY08983.1 - 0.0027 17.7 2.0 0.0027 17.7 2.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CBY08983.1 - 0.0099 15.6 9.2 0.0099 15.6 9.2 3.4 2 2 2 4 4 4 1 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 CBY08983.1 - 0.037 14.3 4.3 0.5 10.7 0.1 3.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.8 CBY08983.1 - 0.15 11.9 7.8 0.34 10.8 7.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GAGA PF09237.11 CBY08983.1 - 9.4 6.1 8.1 9 6.2 0.2 3.0 2 1 1 3 3 3 0 GAGA factor RRM_1 PF00076.22 CBY08984.1 - 4.9e-06 26.3 0.2 1.4e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CBY08986.1 - 2.2e-36 125.6 0.0 7.1e-36 123.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY08986.1 - 8.4e-33 113.7 0.0 1.9e-32 112.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY08986.1 - 2.2e-05 23.4 0.0 4.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY08986.1 - 0.00033 20.1 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY08986.1 - 0.0016 17.4 0.0 0.0068 15.4 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Dynamin_N PF00350.23 CBY08986.1 - 0.0053 16.8 1.4 0.22 11.6 0.1 3.1 3 0 0 3 3 3 1 Dynamin family APH PF01636.23 CBY08986.1 - 0.021 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MH2 PF03166.14 CBY08987.1 - 1.7e-29 103.4 1.7 3.6e-29 102.3 1.7 1.6 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CBY08987.1 - 5.5e-09 36.2 0.8 4.3e-08 33.3 0.8 2.3 1 1 0 1 1 1 1 MH1 domain zf-H2C2_2 PF13465.6 CBY08988.1 - 7.6e-08 32.5 31.5 0.00011 22.5 4.3 3.8 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY08988.1 - 1.1e-07 32.0 25.7 0.0022 18.4 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY08988.1 - 6.6e-07 29.6 22.2 0.0092 16.7 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY08988.1 - 0.0016 18.3 17.8 0.032 14.2 6.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBY08988.1 - 0.013 15.8 5.4 0.013 15.8 5.4 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PorB PF11565.8 CBY08988.1 - 0.053 13.9 0.2 0.17 12.3 0.1 1.8 2 0 0 2 2 2 0 Alpha helical Porin B FimH_man-bind PF09160.10 CBY08988.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 FimH, mannose binding zf-C2H2_jaz PF12171.8 CBY08988.1 - 0.13 12.6 9.6 2.1 8.7 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CBY08988.1 - 0.18 11.7 16.9 0.95 9.4 0.3 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 CBY08988.1 - 0.18 10.9 0.8 0.43 9.7 0.8 1.7 1 0 0 1 1 1 0 Putative actin-like family zf-CHY PF05495.12 CBY08988.1 - 0.32 11.5 10.8 0.91 10.1 10.8 1.8 1 0 0 1 1 1 0 CHY zinc finger zf-CHCC PF10276.9 CBY08988.1 - 0.51 10.4 6.1 2.3 8.3 0.2 3.4 4 0 0 4 4 4 0 Zinc-finger domain zinc_ribbon_9 PF14369.6 CBY08988.1 - 2.5 8.4 11.8 3.4 8.0 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon Trefoil PF00088.18 CBY08989.1 - 1.1e-28 98.8 53.8 2.4e-08 33.7 5.7 4.6 4 0 0 4 4 4 4 Trefoil (P-type) domain Alpha-amylase_C PF02806.18 CBY08989.1 - 3.4e-07 30.6 0.0 1.5e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain 3-dmu-9_3-mt PF06983.13 CBY08989.1 - 0.15 12.6 0.0 39 4.8 0.0 2.7 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase Sulfotransfer_2 PF03567.14 CBY08992.1 - 1.2e-17 64.7 0.1 2.4e-17 63.7 0.1 1.6 2 0 0 2 2 2 1 Sulfotransferase family Astacin PF01400.24 CBY08993.1 - 1.7e-70 236.5 0.0 5.4e-39 133.8 0.0 2.6 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY08993.1 - 9.6e-19 67.3 78.1 1.5e-09 37.9 6.6 7.4 8 0 0 8 8 8 4 Calcium-binding EGF domain Peptidase_M10 PF00413.24 CBY08993.1 - 0.0064 16.3 0.3 7.4 6.4 0.0 3.3 2 1 1 3 3 3 1 Matrixin cEGF PF12662.7 CBY08993.1 - 0.018 14.9 2.1 0.018 14.9 2.1 6.7 8 0 0 8 8 8 0 Complement Clr-like EGF-like TDP43_N PF18694.1 CBY08993.1 - 0.12 12.3 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DUF3267 PF11667.8 CBY08993.1 - 0.15 12.3 0.0 18 5.6 0.0 2.3 2 0 0 2 2 2 0 Putative zincin peptidase Glyoxalase PF00903.25 CBY08994.1 - 0.14 12.3 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RdRP PF05183.12 CBY08995.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA dependent RNA polymerase Collagen PF01391.18 CBY08996.1 - 1.2e-23 82.6 64.7 5.9e-10 38.8 25.9 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CBY08997.1 - 1.1e-41 140.4 135.8 2.1e-09 37.0 25.8 6.1 3 2 3 6 6 6 6 Collagen triple helix repeat (20 copies) Peptidase_M41 PF01434.18 CBY08999.1 - 8.7e-63 211.6 0.0 1.3e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBY08999.1 - 8.7e-41 139.4 0.0 1.5e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY08999.1 - 4e-09 36.1 0.1 1.1e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CBY08999.1 - 1.3e-07 31.9 0.8 3.9e-07 30.4 0.8 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_2 PF07724.14 CBY08999.1 - 0.0028 17.8 0.0 0.0071 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CBY08999.1 - 0.0064 16.3 0.0 0.025 14.3 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CBY08999.1 - 0.025 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 CBY08999.1 - 0.079 13.0 0.4 0.84 9.6 0.4 2.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sdh5 PF03937.16 CBY09000.1 - 7.6e-20 70.7 0.5 1.4e-19 69.9 0.5 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase PUD PF03714.14 CBY09000.1 - 0.08 13.8 0.1 0.13 13.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial pullanase-associated domain Gal-3-0_sulfotr PF06990.11 CBY09001.1 - 8.3e-12 44.7 0.0 1.1e-11 44.3 0.0 1.2 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Gal-3-0_sulfotr PF06990.11 CBY09002.1 - 1.9e-37 129.1 0.2 2.2e-37 128.9 0.2 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase DUF3106 PF11304.8 CBY09002.1 - 0.11 12.9 0.3 0.49 10.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Pkinase PF00069.25 CBY09003.1 - 3e-61 207.1 0.0 5.3e-61 206.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 CBY09003.1 - 2.1e-42 145.7 0.0 3e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 CBY09003.1 - 5.2e-42 143.9 0.2 1.2e-41 142.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY09003.1 - 0.00028 19.8 0.0 0.00028 19.8 0.0 3.0 4 0 0 4 4 4 1 Fungal protein kinase Kinase-like PF14531.6 CBY09003.1 - 0.00048 19.5 0.0 0.0035 16.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY09003.1 - 0.0055 16.1 0.1 0.015 14.6 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY09003.1 - 0.11 12.4 1.5 1.5 8.7 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBY09003.1 - 0.11 12.1 5.4 0.35 10.5 0.1 2.9 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 LRR_9 PF14580.6 CBY09004.1 - 7.2e-14 51.7 3.1 3.5e-11 42.9 3.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CBY09004.1 - 1.5e-13 50.7 19.7 0.00045 20.5 0.4 4.1 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY09004.1 - 6.5e-10 38.6 17.6 6.1e-05 22.7 11.4 3.6 2 2 1 3 3 3 3 Leucine rich repeat DUF2514 PF10721.9 CBY09004.1 - 0.29 11.2 6.7 0.47 10.5 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RabGAP-TBC PF00566.18 CBY09005.1 - 7.4e-13 48.7 0.3 9.7e-13 48.3 0.3 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DEAD PF00270.29 CBY09006.1 - 5e-94 313.0 15.1 5.2e-46 156.6 0.2 5.1 6 0 0 6 6 6 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY09006.1 - 2.3e-57 192.2 1.8 2e-26 92.5 0.0 5.1 5 0 0 5 5 5 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CBY09006.1 - 0.00025 21.4 6.0 0.9 9.8 0.2 4.6 4 2 0 4 4 4 2 AAA domain DUF1264 PF06884.11 CBY09006.1 - 0.042 13.4 0.1 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1264) DnaB_bind PF10410.9 CBY09006.1 - 0.064 13.5 0.1 12 6.2 0.0 2.9 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase SbcCD_C PF13558.6 CBY09006.1 - 0.066 13.5 1.0 20 5.5 0.1 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Bin3 PF06859.12 CBY09006.1 - 7.5 7.2 9.6 35 5.1 1.7 3.9 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) Helicase_C PF00271.31 CBY09007.1 - 2.3e-29 102.0 0.0 3.2e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBY09007.1 - 0.0033 16.7 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 CBY09008.1 - 3e-27 95.5 1.9 2.2e-22 79.6 0.1 2.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase WD40 PF00400.32 CBY09009.1 - 2.2e-35 120.1 6.3 8e-07 29.7 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09009.1 - 1.8e-12 47.4 0.1 0.0054 17.0 0.0 5.5 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CBY09009.1 - 0.0071 15.9 0.0 0.13 11.8 0.0 3.1 3 1 0 3 3 3 1 PQQ-like domain WD40_like PF17005.5 CBY09009.1 - 0.013 14.9 0.0 1.2 8.4 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Elongin_A PF06881.11 CBY09009.1 - 0.25 11.9 3.8 0.53 10.8 3.8 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Thx PF17070.5 CBY09009.1 - 3.5 7.9 7.0 4.5 7.5 0.1 3.4 3 0 0 3 3 3 0 30S ribosomal protein Thx MDD_C PF18376.1 CBY09010.1 - 1.6e-56 191.0 0.0 2.8e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CBY09010.1 - 7.3e-06 26.1 1.5 2.7e-05 24.3 1.5 1.9 3 0 0 3 3 3 1 GHMP kinases N terminal domain Glyco_hydro_72 PF03198.14 CBY09010.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Carboxyl_trans PF01039.22 CBY09011.1 - 1.4e-149 498.9 0.0 1.8e-149 498.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain zf-C3HC4_2 PF13923.6 CBY09011.1 - 6.1e-10 38.8 11.0 6.1e-10 38.8 11.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY09011.1 - 5.4e-08 32.6 9.8 1.3e-07 31.3 9.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY09011.1 - 2.7e-07 30.3 7.9 5.5e-07 29.3 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY09011.1 - 4.5e-07 29.8 8.9 1e-06 28.7 8.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY09011.1 - 4.6e-07 29.7 10.6 9.8e-07 28.6 10.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY09011.1 - 2.4e-06 27.7 10.7 2.4e-06 27.7 10.7 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_10 PF16685.5 CBY09011.1 - 3.7e-06 27.0 5.9 7.7e-06 25.9 5.9 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 CBY09011.1 - 6.6e-05 23.0 9.3 0.00015 21.8 9.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CBY09011.1 - 0.00011 22.0 3.2 0.00026 20.8 3.2 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein MdcE PF06833.11 CBY09011.1 - 0.00015 21.4 0.0 0.097 12.1 0.0 2.6 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) Prok-RING_4 PF14447.6 CBY09011.1 - 0.00043 20.1 10.0 0.00089 19.1 10.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UNC-79 PF14776.6 CBY09011.1 - 0.0087 14.9 3.1 0.015 14.1 3.1 1.3 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 zf-rbx1 PF12678.7 CBY09011.1 - 0.26 11.6 7.1 0.9 9.9 7.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 CBY09011.1 - 0.63 9.7 5.8 1.4 8.7 5.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 CBY09011.1 - 4.4 7.2 6.3 9.7 6.1 6.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Bromodomain PF00439.25 CBY09013.1 - 6.7e-18 64.5 0.5 2.5e-17 62.7 0.1 2.2 2 0 0 2 2 2 1 Bromodomain PHD PF00628.29 CBY09013.1 - 8.8e-06 25.5 11.5 8.8e-06 25.5 11.5 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 CBY09013.1 - 9.5e-06 25.9 2.1 5.6e-05 23.5 1.4 2.7 2 1 0 2 2 2 1 PWWP domain Filament PF00038.21 CBY09013.1 - 0.0025 17.5 1.1 0.0045 16.6 1.1 1.3 1 0 0 1 1 1 1 Intermediate filament protein zf-MYND PF01753.18 CBY09013.1 - 0.0087 16.1 15.1 0.0087 16.1 15.1 3.4 3 1 0 3 3 3 1 MYND finger Zf_RING PF16744.5 CBY09013.1 - 0.034 14.3 5.3 0.18 11.9 5.3 2.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_7 PF02591.15 CBY09013.1 - 0.2 11.8 2.7 2.3 8.5 0.1 3.1 2 0 0 2 2 2 0 C4-type zinc ribbon domain BRK PF07533.16 CBY09015.1 - 1e-05 25.0 0.0 4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 BRK domain Totivirus_coat PF05518.11 CBY09015.1 - 8.8 4.2 6.4 22 2.9 6.4 1.6 1 0 0 1 1 1 0 Totivirus coat protein SNF2_N PF00176.23 CBY09016.1 - 7.6e-62 209.0 0.9 1.2e-61 208.4 0.9 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY09016.1 - 3.5e-19 69.2 0.0 2.5e-18 66.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 CBY09016.1 - 3.2e-13 49.3 1.1 6.2e-12 45.2 0.3 3.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CBY09016.1 - 1.5e-10 41.4 0.0 1.5e-10 41.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 CBY09016.1 - 4.9e-07 30.1 7.9 0.065 13.4 0.0 5.3 6 0 0 6 6 6 2 CHDCT2 (NUC038) domain DEAD PF00270.29 CBY09016.1 - 1.5e-06 28.1 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CBY09016.1 - 0.0025 17.5 0.1 0.01 15.5 0.1 2.0 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Myb_DNA-bind_7 PF15963.5 CBY09016.1 - 0.011 15.6 0.0 0.011 15.6 0.0 3.2 3 0 0 3 3 3 0 Myb DNA-binding like AAA_22 PF13401.6 CBY09016.1 - 0.086 13.1 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.31 CBY09016.1 - 0.83 9.9 13.8 12 6.1 0.1 4.7 5 0 0 5 5 5 0 Myb-like DNA-binding domain Requiem_N PF14051.6 CBY09018.1 - 1.1e-20 73.6 6.0 1.1e-20 73.6 6.0 1.6 2 0 0 2 2 2 1 N-terminal domain of DPF2/REQ. Plectin PF00681.20 CBY09019.1 - 4.7e-53 176.8 2.1 1e-09 38.1 0.0 10.0 7 3 3 10 10 10 7 Plectin repeat EphA2_TM PF14575.6 CBY09019.1 - 0.097 13.6 0.1 74 4.3 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain RNR_N PF08343.10 CBY09019.1 - 0.28 11.2 1.6 12 6.1 0.0 2.9 3 0 0 3 3 3 0 Ribonucleotide reductase N-terminal SH2 PF00017.24 CBY09020.1 - 8e-11 41.9 0.1 1.6e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 SH2 domain RhoGAP PF00620.27 CBY09021.1 - 6e-37 126.8 0.0 8.7e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 CBY09021.1 - 8.3e-11 41.6 12.2 1.3e-10 41.0 12.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 CBY09021.1 - 0.15 12.1 6.1 0.32 11.0 6.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 CBY09021.1 - 0.22 11.5 9.5 0.42 10.6 9.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.11 CBY09021.1 - 0.38 10.7 3.7 0.93 9.5 3.7 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_9 PF13901.6 CBY09021.1 - 6.6 6.7 14.8 0.59 10.1 6.6 2.8 2 1 1 3 3 3 0 Putative zinc-RING and/or ribbon HC2 PF07382.11 CBY09023.1 - 0.005 16.9 6.8 0.0057 16.8 6.8 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 PLAC8 PF04749.17 CBY09024.1 - 3.7e-10 40.7 14.3 5.7e-10 40.1 14.3 1.3 1 0 0 1 1 1 1 PLAC8 family Col_cuticle_N PF01484.17 CBY09024.1 - 0.0038 17.3 0.1 0.0082 16.2 0.1 1.5 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain FAM176 PF14851.6 CBY09024.1 - 0.35 10.5 10.8 0.046 13.4 5.5 2.0 2 0 0 2 2 2 0 FAM176 family UCH PF00443.29 CBY09026.1 - 1.1e-55 189.0 2.4 1.3e-55 188.7 2.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY09026.1 - 5e-34 118.3 7.8 6.3e-34 118.0 7.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FKS1_dom1 PF14288.6 CBY09026.1 - 0.02 15.2 0.8 0.26 11.6 0.2 2.6 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 AAA PF00004.29 CBY09027.1 - 1.5e-39 135.5 0.0 2.6e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CBY09027.1 - 1.9e-28 98.3 0.3 4.7e-28 97.0 0.3 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CBY09027.1 - 2.8e-24 84.9 5.9 2.8e-24 84.9 5.9 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.6 CBY09027.1 - 9.7e-06 25.9 0.4 0.0012 19.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY09027.1 - 1.8e-05 25.2 0.3 0.004 17.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CBY09027.1 - 2.1e-05 24.6 0.0 5.8e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBY09027.1 - 2.3e-05 24.2 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBY09027.1 - 3e-05 23.4 0.0 4.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 CBY09027.1 - 3.6e-05 23.5 0.1 0.00029 20.6 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain IstB_IS21 PF01695.17 CBY09027.1 - 4.6e-05 23.2 0.0 9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 CBY09027.1 - 7.8e-05 22.9 0.2 0.002 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CBY09027.1 - 0.00012 21.4 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CBY09027.1 - 0.0002 21.4 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY09027.1 - 0.0022 18.6 0.0 0.0052 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBY09027.1 - 0.0055 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CBY09027.1 - 0.0095 15.5 0.6 0.24 10.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 CBY09027.1 - 0.013 15.2 0.1 0.075 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBY09027.1 - 0.015 14.7 0.1 0.037 13.4 0.1 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBY09027.1 - 0.018 15.4 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 CBY09027.1 - 0.024 14.0 0.4 5.1 6.4 0.0 2.5 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 CBY09027.1 - 0.026 14.0 0.0 0.078 12.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 CBY09027.1 - 0.045 14.2 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CBY09027.1 - 0.051 13.0 0.0 6.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 CBY09027.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.18 CBY09027.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 CBY09027.1 - 0.09 12.7 0.0 1.5 8.8 0.0 2.3 1 1 2 3 3 3 0 NACHT domain Sigma54_activat PF00158.26 CBY09027.1 - 0.093 12.4 0.0 0.42 10.3 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 CBY09027.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Torsin MCM PF00493.23 CBY09027.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain TarH PF02203.15 CBY09027.1 - 0.11 12.4 0.8 0.2 11.6 0.8 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF2040 PF09745.9 CBY09029.1 - 9.8e-34 116.0 26.8 9.8e-34 116.0 26.8 3.5 2 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Arfaptin PF06456.13 CBY09030.1 - 2e-26 93.0 1.6 3e-26 92.4 1.6 1.3 1 0 0 1 1 1 1 Arfaptin-like domain SPK PF04435.18 CBY09030.1 - 0.018 15.4 0.1 0.074 13.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF545) APG6_N PF17675.1 CBY09030.1 - 0.13 12.7 1.9 0.35 11.4 0.6 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Com_YlbF PF06133.11 CBY09030.1 - 0.82 10.3 4.0 4.5 7.9 0.9 2.8 2 2 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Lipoprotein_20 PF13942.6 CBY09030.1 - 3 7.7 7.4 13 5.6 3.5 3.2 1 1 1 2 2 2 0 YfhG lipoprotein La PF05383.17 CBY09031.1 - 1.5e-15 57.0 0.2 3.4e-15 55.9 0.2 1.5 1 0 0 1 1 1 1 La domain LAMTOR5 PF16672.5 CBY09032.1 - 0.071 13.0 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Tap-RNA_bind PF09162.10 CBY09032.1 - 0.097 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Tap, RNA-binding SVWC PF15430.6 CBY09033.1 - 0.073 13.3 4.3 5.6 7.3 0.2 2.4 2 0 0 2 2 2 0 Single domain von Willebrand factor type C THP2 PF09432.10 CBY09033.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Tho complex subunit THP2 Med7 PF05983.11 CBY09035.1 - 1.8e-37 129.3 3.7 6.2e-37 127.5 3.7 1.7 1 1 0 1 1 1 1 MED7 protein Ribosomal_L18 PF17135.4 CBY09036.1 - 4.1e-89 296.9 3.2 4.5e-89 296.8 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CBY09036.1 - 0.0035 18.0 0.2 0.0078 16.9 0.2 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_S24e PF01282.19 CBY09037.1 - 9e-34 115.3 0.1 9e-34 115.3 0.1 1.9 1 1 1 2 2 2 2 Ribosomal protein S24e Ribosomal_L37ae PF01780.19 CBY09038.1 - 1.4e-36 124.5 4.6 1.5e-36 124.3 4.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Acetyltransf_3 PF13302.7 CBY09039.1 - 3.1e-25 89.5 0.8 4.4e-25 89.0 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CBY09039.1 - 0.0013 18.4 0.1 0.0033 17.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY09039.1 - 0.0015 18.7 0.4 0.005 17.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 CBY09039.1 - 0.0031 17.7 0.2 0.0055 16.9 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_S19e PF01090.19 CBY09040.1 - 1.3e-55 186.8 0.0 1.6e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L29 PF00831.23 CBY09041.1 - 4e-15 55.5 0.6 4e-15 55.5 0.6 2.3 2 0 0 2 2 2 2 Ribosomal L29 protein TPT PF03151.16 CBY09043.1 - 4.6e-14 52.5 18.3 5.7e-14 52.2 18.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY09043.1 - 0.083 13.1 36.3 0.43 10.8 16.8 2.5 2 1 0 2 2 2 0 EamA-like transporter family EbsA PF17255.2 CBY09043.1 - 2 8.8 16.8 0.23 11.8 5.6 3.5 2 2 2 4 4 4 0 EbsA-like protein PUNUT PF16913.5 CBY09043.1 - 3.7 6.7 20.9 27 3.9 20.9 2.2 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Atg14 PF10186.9 CBY09044.1 - 0.00078 18.6 21.8 0.0012 18.0 21.8 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3552 PF12072.8 CBY09044.1 - 0.0028 17.1 35.8 0.0068 15.9 14.9 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) PKcGMP_CC PF16808.5 CBY09044.1 - 0.0079 16.0 4.5 0.0079 16.0 4.5 3.7 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase BST2 PF16716.5 CBY09044.1 - 0.033 14.8 5.7 0.033 14.8 5.7 3.1 2 2 1 3 3 3 0 Bone marrow stromal antigen 2 BLOC1_2 PF10046.9 CBY09044.1 - 0.21 11.9 16.7 0.24 11.7 1.7 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CBY09044.1 - 0.34 9.7 32.9 0.095 11.6 16.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FliD_N PF02465.18 CBY09044.1 - 0.36 11.6 11.4 3 8.6 2.8 2.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF16 PF01519.16 CBY09044.1 - 4.4 7.8 23.4 0.28 11.7 5.9 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 COG2 PF06148.11 CBY09044.1 - 5.4 7.1 14.4 1.2 9.2 2.0 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Galactosyl_T PF01762.21 CBY09046.1 - 5.6e-25 88.3 0.5 9.8e-25 87.5 0.5 1.4 1 0 0 1 1 1 1 Galactosyltransferase 7tm_1 PF00001.21 CBY09048.1 - 4.1e-08 32.9 1.2 4.1e-08 32.9 1.2 2.2 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF4383 PF14325.6 CBY09048.1 - 0.044 14.1 0.4 0.22 11.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) MMACHC PF16690.5 CBY09049.1 - 3e-28 98.9 0.0 3.4e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family CKS PF01111.19 CBY09049.1 - 0.1 12.9 0.3 0.24 11.7 0.2 1.8 1 1 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit MMACHC PF16690.5 CBY09050.1 - 0.0001 22.1 0.0 0.0001 22.1 0.0 1.1 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family MMACHC PF16690.5 CBY09051.1 - 2.8e-07 30.4 0.0 3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Phospholip_A2_1 PF00068.19 CBY09052.1 - 2.6e-16 60.1 7.1 2.6e-16 60.1 7.1 1.7 2 0 0 2 2 2 1 Phospholipase A2 Gal_GalNac_35kD PF17337.2 CBY09052.1 - 0.11 12.5 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Galactose-inhibitable lectin 35 kDa subunit SepSecS PF05889.13 CBY09053.1 - 1.9e-110 369.3 0.0 2.2e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 CBY09053.1 - 9.4e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pkinase PF00069.25 CBY09054.1 - 7.8e-08 32.0 0.3 1e-07 31.6 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CBY09054.1 - 5.7e-06 25.8 0.0 8.3e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY09054.1 - 8.5e-06 25.5 0.0 1.2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY09054.1 - 0.0073 16.3 0.0 2.1 8.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CBY09054.1 - 0.062 12.6 0.2 0.081 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase SelK_SelG PF10961.8 CBY09056.1 - 1.2e-12 48.2 3.4 1.4e-12 48.0 3.4 1.2 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Ras PF00071.22 CBY09057.1 - 7e-07 29.0 0.0 1.3e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 Ras family Ribosomal_S15 PF00312.22 CBY09058.1 - 0.012 15.8 2.9 0.018 15.2 0.5 2.5 3 0 0 3 3 3 0 Ribosomal protein S15 zf-C4H2 PF10146.9 CBY09058.1 - 2.8 8.2 5.9 5.5 7.2 5.9 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein Rep_fac-A_3 PF08661.11 CBY09059.1 - 0.00012 22.4 0.0 0.00016 22.0 0.0 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_C47 PF05543.13 CBY09059.1 - 0.0087 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Staphopain peptidase C47 tRNA_anti-codon PF01336.25 CBY09059.1 - 0.031 14.3 0.0 0.1 12.6 0.0 1.8 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain NIF3 PF01784.18 CBY09060.1 - 7.5e-71 238.6 0.2 1.5e-70 237.7 0.2 1.4 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Stomoxyn PF11585.8 CBY09060.1 - 7.1 6.7 12.4 4.6 7.3 1.0 2.8 3 0 0 3 3 3 0 Insect antimicrobial peptide, stomoxyn Pkinase PF00069.25 CBY09061.1 - 4e-37 128.0 0.0 8.1e-37 127.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.12 CBY09061.1 - 3.2e-29 101.7 1.4 9.6e-29 100.1 0.9 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 CBY09061.1 - 2.3e-21 76.2 0.0 3.7e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY09061.1 - 7.5e-06 25.0 0.0 1.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY09061.1 - 0.00011 21.7 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CBY09066.1 - 9.8e-36 123.5 0.3 1.2e-35 123.2 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09066.1 - 1.6e-29 103.0 0.2 1.9e-29 102.7 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY09066.1 - 0.0002 20.5 0.1 0.0043 16.0 0.0 2.0 1 1 1 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CBY09066.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY09066.1 - 0.0034 17.3 0.1 0.025 14.5 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Collagen PF01391.18 CBY09067.1 - 2.9e-46 155.0 186.0 8e-09 35.1 28.2 7.1 2 2 2 5 5 5 5 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY09067.1 - 4.7e-09 36.7 0.4 6.7e-09 36.2 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY09067.1 - 9.9e-05 23.0 0.2 0.00017 22.2 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF5507 PF17612.2 CBY09067.1 - 0.018 14.7 0.2 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5507) Sec66 PF09802.9 CBY09068.1 - 0.071 12.7 0.5 0.12 11.9 0.1 1.5 1 1 1 2 2 2 0 Preprotein translocase subunit Sec66 Glyco_transf_49 PF13896.6 CBY09069.1 - 1.4e-96 323.8 2.4 1.6e-96 323.5 2.4 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Radical_SAM PF04055.21 CBY09069.1 - 0.032 14.6 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily LRR_8 PF13855.6 CBY09070.1 - 6.7e-10 38.6 1.7 2.3e-08 33.7 0.9 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBY09070.1 - 0.00011 22.5 2.7 0.77 10.3 1.8 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY09070.1 - 0.00052 20.2 1.1 0.79 10.5 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_5 PF13306.6 CBY09070.1 - 0.0013 18.7 4.6 0.0028 17.6 4.6 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) ASXH PF13919.6 CBY09070.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Asx homology domain Laminin_EGF PF00053.24 CBY09070.1 - 0.25 11.5 5.4 0.67 10.1 5.4 1.7 1 0 0 1 1 1 0 Laminin EGF domain LRR_6 PF13516.6 CBY09070.1 - 0.29 11.3 2.3 28 5.1 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat SMODS PF18144.1 CBY09071.1 - 0.23 11.6 6.6 0.096 12.9 0.9 2.5 2 1 1 3 3 3 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain SDH_C PF18317.1 CBY09072.1 - 0.043 13.6 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain DUF3318 PF11780.8 CBY09072.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) GREB1 PF15782.5 CBY09073.1 - 2.1e-41 141.3 0.0 1.9e-38 131.5 0.0 2.1 2 0 0 2 2 2 2 Gene regulated by oestrogen in breast cancer DUF2382 PF09557.10 CBY09075.1 - 0.35 11.1 7.8 0.13 12.5 4.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2382) SMN PF06003.12 CBY09076.1 - 0.053 12.8 2.7 0.085 12.1 2.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RP-C_C PF11800.8 CBY09076.1 - 0.28 11.3 6.6 0.41 10.7 6.6 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region PIEZO PF15917.5 CBY09076.1 - 7.7 5.9 9.6 11 5.4 9.6 1.2 1 0 0 1 1 1 0 Piezo PapD_C PF02753.17 CBY09077.1 - 0.061 13.7 0.7 1.5 9.2 0.3 2.8 3 0 0 3 3 3 0 Pili assembly chaperone PapD, C-terminal domain Protocadherin PF08374.11 CBY09078.1 - 2.1e-05 24.6 2.1 2.7e-05 24.2 2.1 1.1 1 0 0 1 1 1 1 Protocadherin Bestrophin PF01062.21 CBY09079.1 - 0.08 12.3 1.1 0.087 12.2 1.1 1.0 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel SH2 PF00017.24 CBY09080.1 - 2.4e-07 30.7 0.0 4.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 CBY09080.1 - 0.079 13.3 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 SOCS box Jacalin PF01419.17 CBY09081.1 - 0.0011 18.9 0.0 0.0023 17.8 0.0 1.5 1 1 0 1 1 1 1 Jacalin-like lectin domain Gag_p15 PF08723.10 CBY09082.1 - 0.096 12.9 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Gag protein p15 Zona_pellucida PF00100.23 CBY09084.1 - 4.6e-18 66.0 11.8 5.8e-18 65.6 11.8 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain hGDE_N PF14699.6 CBY09084.1 - 0.0037 17.3 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme GTP_EFTU PF00009.27 CBY09087.1 - 3.1e-54 183.5 0.0 5.4e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBY09087.1 - 2.8e-40 137.1 0.0 5.7e-40 136.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBY09087.1 - 3e-13 50.0 0.8 8e-13 48.6 0.1 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY09087.1 - 0.00086 19.4 0.1 0.021 14.9 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CBY09087.1 - 0.0091 15.9 0.5 0.028 14.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 G-alpha PF00503.20 CBY09087.1 - 0.19 10.8 0.1 0.42 9.7 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit SLBP_RNA_bind PF15247.6 CBY09088.1 - 9e-23 80.2 3.4 9e-23 80.2 3.4 1.9 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Lipl32 PF12103.8 CBY09088.1 - 0.055 13.1 0.8 0.17 11.5 0.1 2.1 2 1 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Peptidase_M76 PF09768.9 CBY09089.1 - 4.4e-16 59.1 0.3 6e-16 58.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase M76 family Fer4_24 PF18109.1 CBY09089.1 - 0.094 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain Mito_carr PF00153.27 CBY09090.1 - 3.3e-63 209.7 0.6 1.7e-20 72.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CBY09090.1 - 0.019 14.1 0.1 0.31 10.1 0.0 2.6 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Peptidase_M22 PF00814.25 CBY09091.1 - 7.1e-86 288.3 0.0 8.5e-86 288.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 CBY09091.1 - 0.0025 17.6 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus DUF1149 PF06619.11 CBY09091.1 - 0.05 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1149) Hormone_5 PF00184.17 CBY09091.1 - 0.2 12.5 1.8 0.4 11.5 1.8 1.4 1 0 0 1 1 1 0 Neurohypophysial hormones, C-terminal Domain ERO1 PF04137.15 CBY09092.1 - 9.2e-96 321.1 0.1 1.1e-95 320.9 0.1 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) zf-RING_2 PF13639.6 CBY09094.1 - 2.8e-12 46.8 10.4 2.8e-12 46.8 10.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CBY09094.1 - 7.4e-08 32.0 7.0 7.4e-08 32.0 7.0 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBY09094.1 - 9.8e-08 31.7 10.1 9.8e-08 31.7 10.1 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY09094.1 - 3.9e-07 30.3 10.2 3.9e-07 30.3 10.2 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 CBY09094.1 - 1.1e-05 25.5 6.7 1.1e-05 25.5 6.7 2.4 2 0 0 2 2 2 1 zinc-ribbon zf-RING_UBOX PF13445.6 CBY09094.1 - 4.2e-05 23.5 3.8 4.2e-05 23.5 3.8 2.3 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY09094.1 - 7.8e-05 22.6 7.8 7.8e-05 22.6 7.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY09094.1 - 0.0002 21.1 9.5 0.0002 21.1 9.5 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY09094.1 - 0.00084 19.3 4.7 0.00084 19.3 4.7 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.11 CBY09094.1 - 0.0019 18.2 0.7 0.0019 18.2 0.7 1.6 2 0 0 2 2 2 1 Baculovirus U-box/Ring-like domain Zn_ribbon_17 PF17120.5 CBY09094.1 - 0.0021 17.6 9.8 0.0021 17.6 9.8 2.6 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBY09094.1 - 0.0022 17.8 9.9 0.0022 17.8 9.9 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY09094.1 - 0.0024 17.7 10.5 0.0024 17.7 10.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 CBY09094.1 - 0.0045 16.9 4.7 0.0045 16.9 4.7 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 Rtf2 PF04641.12 CBY09094.1 - 1.5 8.1 8.2 0.042 13.2 1.2 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger Zf_RING PF16744.5 CBY09094.1 - 2.2 8.4 16.9 0.91 9.7 5.3 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger Trm112p PF03966.16 CBY09094.1 - 3.4 8.3 6.9 13 6.5 0.7 3.1 3 0 0 3 3 3 0 Trm112p-like protein HypA PF01155.19 CBY09094.1 - 6.8 6.8 16.8 0.81 9.7 3.2 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Y_phosphatase PF00102.27 CBY09096.1 - 6.3e-06 25.9 1.1 6.5e-06 25.9 1.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 CBY09097.1 - 1.6e-42 145.7 2.0 1.6e-42 145.7 2.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase FERM_C PF09380.10 CBY09097.1 - 2.7e-08 34.1 3.4 5.8e-08 33.0 3.4 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CBY09097.1 - 8.6e-08 32.6 0.3 8e-06 26.2 0.3 2.6 1 1 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CBY09097.1 - 3.8e-06 26.8 0.0 1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain PDZ_6 PF17820.1 CBY09097.1 - 5.6e-05 22.9 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY09097.1 - 0.0007 19.9 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY09097.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 PDZ domain E1-E2_ATPase PF00122.20 CBY09098.1 - 2.1e-17 63.2 0.0 8.5e-17 61.3 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CBY09098.1 - 5.4e-15 56.2 0.1 4.9e-07 30.3 0.3 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY09098.1 - 0.0021 18.1 0.0 0.0055 16.8 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Pirin_C_2 PF17954.1 CBY09098.1 - 0.019 15.1 0.1 0.84 9.9 0.0 2.5 2 0 0 2 2 2 0 Quercetinase C-terminal cupin domain WD40 PF00400.32 CBY09099.1 - 2.5e-27 94.5 21.2 8.8e-07 29.5 0.9 8.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09099.1 - 2.6e-11 43.7 5.0 0.0076 16.5 0.2 6.3 5 1 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 CBY09099.1 - 0.00081 19.2 0.1 0.0022 17.7 0.1 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.10 CBY09099.1 - 0.007 16.2 0.6 0.007 16.2 0.6 2.0 2 0 0 2 2 2 1 HIRA B motif Ank_2 PF12796.7 CBY09100.1 - 2.7e-102 335.5 20.1 2.7e-14 53.5 0.7 10.5 3 3 9 13 13 13 13 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY09100.1 - 7e-101 329.0 17.9 9e-10 38.6 0.0 15.9 6 5 9 15 15 15 15 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY09100.1 - 1.5e-89 293.3 31.5 6e-11 42.6 0.0 14.0 6 5 11 17 17 17 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY09100.1 - 1.6e-84 267.6 13.0 6.4e-06 26.1 0.1 18.9 19 0 0 19 19 19 14 Ankyrin repeat Ank PF00023.30 CBY09100.1 - 2.3e-81 264.9 19.4 2.4e-05 24.6 0.1 18.1 18 0 0 18 18 18 16 Ankyrin repeat PARP PF00644.20 CBY09100.1 - 2.2e-25 89.4 1.6 9.3e-23 80.8 1.6 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_1 PF00536.30 CBY09100.1 - 2.9e-10 40.4 0.2 7.4e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY09100.1 - 1.6e-09 37.7 0.1 4.6e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4878 PF12870.7 CBY09100.1 - 0.12 12.7 0.0 3 8.2 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4878) DDOST_48kD PF03345.14 CBY09101.1 - 3.4e-85 286.4 0.0 4.9e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2194 PF09960.9 CBY09101.1 - 0.0015 17.0 0.0 0.0021 16.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) DUF4485 PF14846.6 CBY09102.1 - 0.025 14.6 0.1 0.061 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DUF3116 PF11313.8 CBY09102.1 - 0.076 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) MA3 PF02847.17 CBY09103.1 - 0.22 11.5 11.2 0.11 12.5 2.9 3.6 2 1 1 3 3 3 0 MA3 domain DUF5123 PF17161.4 CBY09103.1 - 2.1 9.5 4.7 31 5.7 0.4 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) CUB PF00431.20 CBY09104.1 - 1.3e-93 308.8 7.4 1.1e-27 96.5 0.0 5.7 6 0 0 6 6 6 5 CUB domain Astacin PF01400.24 CBY09104.1 - 1.3e-65 220.6 0.1 2.1e-65 219.9 0.1 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 CBY09104.1 - 5.7e-24 84.1 31.5 1.3e-12 47.8 10.6 3.0 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CBY09104.1 - 3.2e-11 43.2 25.8 9.2e-06 25.8 11.5 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF PF00008.27 CBY09104.1 - 2.7e-07 30.8 21.9 0.00052 20.3 6.7 2.8 2 0 0 2 2 2 2 EGF-like domain CUB_2 PF02408.20 CBY09104.1 - 4.2e-07 29.8 2.9 0.011 15.5 0.0 4.7 4 1 0 4 4 4 1 CUB-like domain cEGF PF12662.7 CBY09104.1 - 2e-06 27.6 10.6 5.4e-05 23.0 2.0 4.0 5 0 0 5 5 4 2 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY09104.1 - 2e-05 24.7 26.7 0.002 18.3 7.6 3.3 3 0 0 3 3 3 2 EGF domain Peptidase_M10 PF00413.24 CBY09104.1 - 0.0018 18.2 0.7 0.46 10.3 0.2 2.7 2 1 1 3 3 3 2 Matrixin DUF4223 PF13978.6 CBY09104.1 - 0.0079 16.1 1.4 16 5.5 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4223) hEGF PF12661.7 CBY09104.1 - 0.02 15.5 6.5 0.02 15.5 6.5 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF Reprolysin_4 PF13583.6 CBY09104.1 - 0.022 14.4 0.1 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Ribosomal_S27e PF01667.17 CBY09104.1 - 0.073 12.8 2.3 0.67 9.7 0.1 2.8 2 0 0 2 2 2 0 Ribosomal protein S27 I-set PF07679.16 CBY09105.1 - 0.00017 21.6 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain DUF3659 PF12396.8 CBY09105.1 - 0.0071 16.2 1.2 0.0071 16.2 1.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3659) PBCV_basic_adap PF08789.10 CBY09105.1 - 0.019 15.0 0.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain Ank_2 PF12796.7 CBY09106.1 - 5.2e-30 103.9 2.2 5.6e-18 65.3 0.1 2.8 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY09106.1 - 4.5e-27 94.1 3.9 3.1e-09 37.2 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CBY09106.1 - 4e-26 90.3 11.7 1.1e-07 32.0 0.4 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CBY09106.1 - 1.4e-25 89.0 6.8 2.8e-08 33.9 0.4 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY09106.1 - 5.1e-19 66.4 8.0 3.6e-05 23.8 0.0 5.8 5 1 0 5 5 5 4 Ankyrin repeat Peptidase_M10 PF00413.24 CBY09110.1 - 1.3e-39 135.6 0.1 2.1e-39 134.9 0.1 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 CBY09110.1 - 4.2e-06 26.6 0.1 0.22 11.5 0.2 3.3 3 0 0 3 3 3 2 Hemopexin PG_binding_1 PF01471.18 CBY09110.1 - 7.4e-06 26.1 0.1 2.7e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 CBY09110.1 - 0.0019 18.7 0.1 0.0043 17.6 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CBY09110.1 - 0.032 13.8 0.1 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 CBY09110.1 - 0.037 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 CBY09110.1 - 0.04 13.1 0.1 0.066 12.4 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 CBY09110.1 - 0.045 12.3 0.0 0.082 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase family Astacin PF01400.24 CBY09110.1 - 0.047 13.3 1.2 4.8 6.7 0.3 2.4 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CBY09110.1 - 0.058 13.0 0.2 0.093 12.4 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CBY09110.1 - 0.059 13.5 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Guanylate_cyc PF00211.20 CBY09111.1 - 4.5e-101 336.1 0.3 1.8e-50 171.1 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 CBY09111.1 - 3e-18 66.2 1.8 3.6e-18 65.9 0.1 1.9 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region AA_permease PF00324.21 CBY09111.1 - 0.00023 19.9 1.6 0.00051 18.8 1.6 1.5 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.16 CBY09111.1 - 0.76 10.2 4.9 3.7 7.9 0.0 3.5 3 0 0 3 3 3 0 Divalent cation transporter DUF4383 PF14325.6 CBY09111.1 - 0.81 10.0 0.0 0.81 10.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) HLH PF00010.26 CBY09112.1 - 0.00074 19.4 3.6 0.0018 18.2 3.6 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain R3H-assoc PF13902.6 CBY09112.1 - 0.012 16.0 2.1 0.017 15.5 2.1 1.2 1 0 0 1 1 1 0 R3H-associated N-terminal domain PALP PF00291.25 CBY09114.1 - 3.9e-10 39.6 0.0 5.1e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 CBY09115.1 - 1.1e-07 31.5 0.0 1.3e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltrans_RNA PF04452.14 CBY09115.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase SPRY PF00622.28 CBY09116.1 - 2e-25 89.2 0.1 5.9e-25 87.7 0.1 1.9 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 CBY09116.1 - 2.5e-22 79.3 0.5 4.4e-22 78.6 0.2 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CBY09116.1 - 0.047 13.7 5.5 0.08 12.9 0.3 3.0 3 0 0 3 3 3 0 LisH AFG1_ATPase PF03969.16 CBY09117.1 - 1e-78 264.8 0.6 5.5e-76 255.8 0.1 2.0 1 1 1 2 2 2 2 AFG1-like ATPase VGCC_alpha2 PF08473.11 CBY09118.1 - 3.8e-14 52.3 2.2 1.2e-11 44.1 0.3 2.2 2 0 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd dCache_1 PF02743.18 CBY09118.1 - 2.2e-10 40.8 0.1 9.4e-09 35.4 0.0 2.7 3 0 0 3 3 3 1 Cache domain fn3 PF00041.21 CBY09119.1 - 8.2e-07 29.3 0.0 0.044 14.1 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Baculo_PEP_C PF04513.12 CBY09119.1 - 0.1 12.7 5.3 0.2 11.7 5.4 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HBD PF18534.1 CBY09119.1 - 0.11 12.7 1.3 0.19 11.9 0.4 1.9 2 0 0 2 2 2 0 Helical bundle domain DUF2935 PF11155.8 CBY09119.1 - 0.28 11.5 4.2 0.36 11.2 2.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF3209 PF11483.8 CBY09119.1 - 0.6 10.6 4.1 0.67 10.4 2.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) TMPIT PF07851.13 CBY09119.1 - 0.62 9.3 6.8 0.91 8.7 6.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein FadA PF09403.10 CBY09119.1 - 1.6 9.2 15.9 3.1 8.3 11.4 3.2 1 1 0 1 1 1 0 Adhesion protein FadA Aldedh PF00171.22 CBY09121.1 - 4.6e-70 236.4 0.1 1.5e-57 195.1 0.1 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Pkinase PF00069.25 CBY09121.1 - 3.7e-55 187.1 0.0 9.8e-55 185.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain CNH PF00780.22 CBY09121.1 - 1e-29 104.1 0.8 1.9e-29 103.2 0.8 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 CBY09121.1 - 1.6e-29 103.0 0.0 3.5e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CBY09121.1 - 5.8e-10 38.9 4.7 1.3e-09 37.8 4.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 CBY09121.1 - 2e-05 24.1 0.1 5e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 CBY09121.1 - 0.0026 18.4 0.2 0.0051 17.5 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 CBY09121.1 - 0.034 13.5 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY09121.1 - 0.31 10.9 2.3 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY09121.1 - 1.3 8.6 6.5 0.91 9.1 0.0 2.8 3 0 0 3 3 3 0 Choline/ethanolamine kinase DUF1548 PF07579.11 CBY09123.1 - 0.059 13.7 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) DUF2120 PF09893.9 CBY09123.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) AAA_12 PF13087.6 CBY09124.1 - 7.6e-47 159.5 0.0 1.9e-46 158.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBY09124.1 - 2e-06 27.8 0.3 1.6e-05 24.8 0.2 2.2 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 CBY09124.1 - 0.031 14.1 0.0 0.08 12.8 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain YhfT PF10797.9 CBY09124.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function PRP1_N PF06424.12 CBY09124.1 - 9.5 6.6 7.0 8.4 6.8 1.8 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Glutaredoxin PF00462.24 CBY09125.1 - 8.1e-30 102.8 0.0 9.6e-14 51.4 0.0 2.8 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 CBY09125.1 - 2e-13 50.2 0.2 6.6e-13 48.5 0.2 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CBY09125.1 - 3.1e-05 24.4 0.1 0.02 15.4 0.1 3.1 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY09125.1 - 0.00014 22.2 0.8 0.68 10.3 0.1 3.3 2 1 1 3 3 3 2 Thioredoxin-like HyaE PF07449.11 CBY09125.1 - 0.00062 19.7 0.0 0.19 11.7 0.1 3.0 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE DIM1 PF02966.16 CBY09125.1 - 0.001 18.9 0.0 0.0029 17.4 0.0 1.7 2 0 0 2 2 2 1 Mitosis protein DIM1 GST_N_3 PF13417.6 CBY09125.1 - 0.042 14.3 0.0 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 CBY09125.1 - 0.082 13.0 0.3 0.52 10.4 0.2 2.2 2 1 0 2 2 2 0 Thioredoxin domain TrbC_Ftype PF09673.10 CBY09125.1 - 0.088 12.9 0.1 4.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein XLF PF09302.11 CBY09127.1 - 0.0081 16.3 3.7 0.49 10.5 0.1 2.6 2 1 1 3 3 3 2 XLF-Cernunnos, XRcc4-like factor, NHEJ component NUDIX PF00293.28 CBY09128.1 - 9.3e-09 35.4 0.0 2.9e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain 2Fe-2S_thioredx PF01257.19 CBY09129.1 - 5e-54 182.1 0.1 5.9e-54 181.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Cpn10 PF00166.21 CBY09130.1 - 6.3e-25 87.1 0.0 7.5e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.21 CBY09131.1 - 6.3e-25 87.1 0.0 7.5e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Orn_Arg_deC_N PF02784.16 CBY09132.1 - 6.1e-15 55.3 0.0 7.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Zip PF02535.22 CBY09133.1 - 2e-47 162.0 18.9 9.4e-42 143.4 10.7 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter Laminin_EGF PF00053.24 CBY09133.1 - 1.6 9.0 13.6 2.7 8.2 12.7 1.9 1 1 0 1 1 1 0 Laminin EGF domain Methyltransf_23 PF13489.6 CBY09134.1 - 7.2e-17 61.7 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY09134.1 - 4.7e-12 46.5 0.0 1.7e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY09134.1 - 1.1e-11 45.2 0.0 4.7e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY09134.1 - 7e-09 35.7 0.0 1.4e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY09134.1 - 5.5e-08 33.4 0.0 1.5e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CBY09134.1 - 0.0047 16.4 0.0 0.028 13.8 0.0 2.0 1 1 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.18 CBY09134.1 - 0.0093 15.5 0.0 0.7 9.3 0.0 2.4 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_28 PF02636.17 CBY09134.1 - 0.017 14.8 0.1 0.13 11.9 0.0 2.3 2 1 1 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Peptidase_M3_N PF08439.10 CBY09134.1 - 0.059 13.6 0.8 1.6 9.0 0.3 2.6 3 0 0 3 3 3 0 Oligopeptidase F NNMT_PNMT_TEMT PF01234.17 CBY09134.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family HlyD_D4 PF16572.5 CBY09134.1 - 0.14 12.0 0.4 0.27 11.1 0.4 1.4 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Beach PF02138.18 CBY09135.1 - 2.4e-122 407.6 5.2 4.7e-122 406.7 5.2 1.5 1 0 0 1 1 1 1 Beige/BEACH domain DUF4800 PF16057.5 CBY09135.1 - 6.9e-88 294.2 2.0 1.8e-87 292.8 2.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) PH_BEACH PF14844.6 CBY09135.1 - 3.5e-19 68.7 1.8 2.8e-18 65.8 0.0 3.2 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 CBY09135.1 - 9.8e-18 64.4 0.8 5.1e-17 62.0 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) WD40 PF00400.32 CBY09135.1 - 2.9e-07 31.1 10.6 0.011 16.6 1.5 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09135.1 - 7.1e-05 23.0 1.3 0.051 13.9 0.0 4.1 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Aminotran_1_2 PF00155.21 CBY09136.1 - 7.3e-57 193.2 0.0 8.7e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBY09136.1 - 9e-08 31.7 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 CBY09136.1 - 0.085 11.6 0.1 0.18 10.5 0.1 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 CBY09136.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Lipase_GDSL_2 PF13472.6 CBY09137.1 - 9.5e-05 22.9 0.0 0.00017 22.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_transf_8 PF01501.20 CBY09138.1 - 5.8e-10 39.1 0.0 1.3e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF4207 PF13904.6 CBY09139.1 - 0.0016 18.2 41.9 0.0016 18.2 41.9 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4207) IPK PF03770.16 CBY09140.1 - 4.8e-47 160.4 0.0 6.1e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase MmgE_PrpD PF03972.14 CBY09141.1 - 0.25 9.8 0.1 0.32 9.5 0.1 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Peptidase_M14 PF00246.24 CBY09142.1 - 6.1e-07 29.5 0.0 6.3e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_M14 PF00246.24 CBY09143.1 - 1.5e-48 166.1 0.0 2.3e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY09143.1 - 0.029 14.8 0.4 0.11 12.9 0.2 2.0 2 0 0 2 2 2 0 Carboxypeptidase activation peptide TssN PF17555.2 CBY09145.1 - 1.9 7.8 7.7 2.5 7.4 7.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN CRPA PF05745.11 CBY09145.1 - 4.9 7.1 12.5 1.6 8.7 5.3 2.1 1 1 1 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Trypsin PF00089.26 CBY09147.1 - 3.8e-45 154.4 1.5 6.2e-45 153.7 1.5 1.4 1 0 0 1 1 1 1 Trypsin HLH PF00010.26 CBY09148.1 - 1.5e-16 60.0 0.1 1.5e-16 60.0 0.1 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Cas9-BH PF16593.5 CBY09148.1 - 0.091 12.5 2.8 0.32 10.7 1.7 2.1 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 Glyco_transf_49 PF13896.6 CBY09152.1 - 1e-97 327.5 0.2 1.2e-97 327.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan zf-MYND PF01753.18 CBY09153.1 - 0.00018 21.5 17.3 0.00018 21.5 17.3 2.3 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 CBY09153.1 - 0.015 15.4 8.4 0.036 14.2 8.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ECH_2 PF16113.5 CBY09154.1 - 0.18 11.2 4.2 0.38 10.2 4.2 1.5 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Latarcin PF10279.9 CBY09154.1 - 0.25 11.8 3.3 0.91 10.0 3.3 2.0 1 0 0 1 1 1 0 Latarcin precursor RPW8 PF05659.11 CBY09154.1 - 1.4 8.6 7.9 0.25 11.0 2.7 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 ISG65-75 PF11727.8 CBY09154.1 - 1.4 8.1 12.2 6.7 5.9 0.6 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein FeoB_Cyto PF17910.1 CBY09154.1 - 1.4 9.5 4.7 3.1 8.4 2.8 2.4 1 1 1 2 2 2 0 FeoB cytosolic helical domain TEX33 PF15400.6 CBY09156.1 - 0.003 18.1 0.4 2.2 8.8 0.1 3.4 3 0 0 3 3 3 2 Testis-expressed sequence 33 protein family FSA_C PF10479.9 CBY09156.1 - 0.7 8.0 10.1 0.89 7.6 10.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 CBY09156.1 - 2.4 8.1 29.9 4.3 7.3 29.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein CUB PF00431.20 CBY09158.1 - 0 1903.7 44.8 4.3e-31 107.5 0.1 27.3 27 0 0 27 27 27 27 CUB domain EGF PF00008.27 CBY09158.1 - 1.6e-10 41.1 110.2 3e-08 33.8 3.3 9.5 8 1 0 8 8 8 3 EGF-like domain CUB_2 PF02408.20 CBY09158.1 - 3.4e-10 39.7 49.8 0.53 10.1 0.1 17.2 19 2 0 19 19 19 6 CUB-like domain EGF_CA PF07645.15 CBY09158.1 - 7e-09 35.8 20.3 4.9e-06 26.7 7.0 8.1 6 2 2 8 8 8 3 Calcium-binding EGF domain EGF_3 PF12947.7 CBY09158.1 - 6.8e-07 29.4 18.4 7.2e-06 26.1 3.8 8.7 7 1 1 8 8 8 3 EGF domain FXa_inhibition PF14670.6 CBY09158.1 - 0.0024 18.1 8.8 0.0024 18.1 8.8 8.7 4 3 4 8 8 8 2 Coagulation Factor Xa inhibitory site RPN6_N PF18055.1 CBY09159.1 - 3e-32 111.4 1.5 5.9e-32 110.5 0.3 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CBY09159.1 - 1.6e-13 51.1 4.7 1.7e-13 51.0 2.9 2.0 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CBY09159.1 - 7.7e-06 25.5 0.7 1.5e-05 24.6 0.7 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain Borrelia_REV PF03978.13 CBY09159.1 - 0.067 13.1 0.5 0.067 13.1 0.5 2.5 2 2 0 2 2 2 0 Borrelia burgdorferi REV protein CX9C PF16860.5 CBY09160.1 - 0.0011 18.9 6.1 0.0056 16.7 0.6 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 CBY09160.1 - 0.022 14.7 1.0 0.022 14.7 1.0 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 CBY09160.1 - 0.045 14.1 7.2 2.4 8.5 0.1 3.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 CBY09160.1 - 0.26 11.0 6.6 0.23 11.2 1.5 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Arf PF00025.21 CBY09162.1 - 5.8e-66 221.2 0.9 7e-66 221.0 0.9 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY09162.1 - 5.6e-15 55.6 0.1 9.4e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY09162.1 - 1.1e-13 51.1 0.2 1.3e-13 50.9 0.2 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY09162.1 - 1.7e-11 43.9 1.1 2.2e-08 33.7 0.8 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY09162.1 - 1.7e-11 43.9 0.1 2.2e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY09162.1 - 7.4e-08 32.0 0.3 8.9e-08 31.8 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY09162.1 - 2.1e-07 31.0 0.0 3.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY09162.1 - 0.018 14.6 0.1 0.19 11.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 CBY09162.1 - 0.048 13.2 0.1 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 CBY09162.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.6 1 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CBY09162.1 - 0.072 12.6 0.8 0.47 10.0 0.8 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF953 PF06110.11 CBY09162.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AAA_25 PF13481.6 CBY09162.1 - 0.094 12.3 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CBY09162.1 - 0.14 12.3 0.2 2.3 8.2 0.0 2.0 1 1 0 2 2 2 0 Dynamin family OST3_OST6 PF04756.13 CBY09163.1 - 1.5e-82 277.3 0.0 1.7e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF4131 PF13567.6 CBY09163.1 - 0.0091 15.7 0.9 0.95 9.1 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) BTB_3 PF16017.5 CBY09164.1 - 1.7e-44 150.2 0.0 2.7e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 CBY09164.1 - 0.00053 20.3 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain AAA_31 PF13614.6 CBY09164.1 - 0.041 13.8 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DCP1 PF06058.13 CBY09165.1 - 3.3e-31 107.6 0.2 4.9e-31 107.1 0.2 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 CBY09165.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus Glyco_hydro_18 PF00704.28 CBY09167.1 - 3.4e-85 286.5 0.4 5.9e-85 285.7 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LPMO_10 PF03067.15 CBY09167.1 - 1.8e-30 107.0 0.2 6.5e-30 105.2 0.2 2.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY09167.1 - 3.9e-24 84.6 30.8 8.5e-13 48.3 6.5 4.2 4 0 0 4 4 4 2 Chitin binding Peritrophin-A domain DAG_kinase_N PF14513.6 CBY09167.1 - 0.11 12.7 0.3 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus RAP1 PF07218.11 CBY09167.1 - 0.61 8.3 7.2 0.93 7.7 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PRR18 PF15671.5 CBY09167.1 - 5.7 6.8 12.3 0.12 12.3 5.1 1.8 2 0 0 2 2 2 0 Proline-rich protein family 18 LptC PF06835.13 CBY09168.1 - 0.071 12.7 0.2 0.071 12.7 0.2 2.0 3 0 0 3 3 3 0 Lipopolysaccharide-assembly, LptC-related DUF4522 PF15022.6 CBY09168.1 - 2.9 8.2 5.3 2.1 8.6 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4522) DUF1492 PF07374.11 CBY09169.1 - 0.2 11.8 2.4 0.16 12.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) CorA PF01544.18 CBY09169.1 - 0.45 9.8 5.4 0.65 9.3 5.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein OEP PF02321.18 CBY09169.1 - 4.5 7.0 7.5 1.2 8.9 3.4 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein MFS_1 PF07690.16 CBY09170.1 - 2.2e-38 132.1 18.6 3.1e-37 128.3 18.6 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY09170.1 - 3.6e-10 39.3 7.4 3.6e-10 39.3 7.4 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CBY09170.1 - 5.3e-09 35.1 1.6 8.6e-09 34.3 1.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CBY09170.1 - 2.8e-07 29.2 13.7 0.0079 14.5 0.8 4.1 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 CBY09170.1 - 0.0035 16.2 13.5 0.077 11.8 0.9 2.9 2 1 0 3 3 3 2 MFS_1 like family Mucin PF01456.17 CBY09170.1 - 0.1 12.6 3.8 0.08 12.9 1.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2631 PF10939.8 CBY09170.1 - 3.4 7.6 6.3 0.39 10.6 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) FOXP-CC PF16159.5 CBY09171.1 - 0.058 14.0 0.0 0.058 14.0 0.0 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain Phage_TAC_11 PF11836.8 CBY09171.1 - 0.13 12.4 1.1 5.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 Radial_spoke_3 PF06098.11 CBY09171.1 - 1.5 8.1 20.4 0.57 9.4 11.4 2.0 1 1 1 2 2 2 0 Radial spoke protein 3 Fmp27_WPPW PF10359.9 CBY09171.1 - 1.9 7.2 12.7 2 7.2 12.2 1.2 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FapA PF03961.13 CBY09171.1 - 2.6 6.5 8.8 3 6.4 8.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 CBY09171.1 - 7.9 5.5 16.9 21 4.1 0.3 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 CBY09172.1 - 3.1e-30 104.0 26.0 4e-17 62.0 12.3 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 CBY09172.1 - 6.2e-11 42.2 31.3 9.8e-07 28.8 14.3 2.6 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 CBY09172.1 - 0.00016 22.2 15.3 0.0084 16.6 5.6 2.4 2 0 0 2 2 2 2 bZIP Maf transcription factor Rh5 PF18515.1 CBY09172.1 - 0.0041 16.5 2.4 0.14 11.5 0.2 2.4 2 0 0 2 2 2 1 Rh5 coiled-coil domain ASD2 PF08687.11 CBY09172.1 - 0.009 15.6 4.6 0.06 12.9 0.9 2.5 3 0 0 3 3 3 1 Apx/Shroom domain ASD2 HAUS4 PF14735.6 CBY09172.1 - 0.057 13.1 2.0 8.3 6.0 0.4 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 Spc7 PF08317.11 CBY09172.1 - 0.11 11.3 4.3 0.19 10.6 4.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0203 PF05254.12 CBY09172.1 - 0.13 12.5 3.9 7.7 6.8 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) CX9C PF16860.5 CBY09172.1 - 0.17 11.9 5.3 6.8 6.8 0.4 2.7 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 CBY09172.1 - 1.2 9.4 8.6 4.3 7.6 0.3 3.1 3 1 0 3 3 3 0 Cytochrome oxidase c subunit VIb DUF3128 PF11326.8 CBY09172.1 - 1.8 9.0 6.1 19 5.7 1.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) EMP24_GP25L PF01105.24 CBY09172.1 - 1.9 8.4 4.3 7.4 6.5 2.9 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Nnf1 PF03980.14 CBY09172.1 - 7.2 7.0 10.1 1.1 9.7 4.5 2.3 2 0 0 2 2 2 0 Nnf1 TPR_MLP1_2 PF07926.12 CBY09172.1 - 7.8 6.6 13.2 0.48 10.5 5.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein NINJA_B PF16136.5 CBY09172.1 - 8 6.9 17.2 4.2 7.8 1.0 3.2 3 0 0 3 3 3 0 Putative nuclear localisation signal MAS20 PF02064.15 CBY09175.1 - 0.085 13.0 0.5 0.11 12.6 0.5 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor Myb_DNA-bind_4 PF13837.6 CBY09176.1 - 5.8e-06 26.6 0.6 9.6e-06 25.9 0.6 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CBY09176.1 - 0.0016 18.7 0.3 0.0035 17.6 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 CBY09176.1 - 0.008 17.1 0.5 0.018 16.0 0.4 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 CBY09176.1 - 0.03 15.0 0.2 0.085 13.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Mito_carr PF00153.27 CBY09177.1 - 2.8e-58 193.8 0.1 7.6e-20 70.6 0.0 3.8 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CBY09177.1 - 3.5e-08 33.8 4.7 0.039 14.4 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY09177.1 - 3.9e-07 29.5 0.1 0.0064 16.3 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBY09177.1 - 5.5e-07 28.7 0.3 0.0039 16.6 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY09177.1 - 1.3e-06 28.1 0.3 0.015 15.1 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY09177.1 - 2.2e-06 26.9 0.5 0.0022 17.4 0.0 2.9 2 0 0 2 2 2 2 EF hand DUF5379 PF17350.2 CBY09177.1 - 0.059 13.6 0.0 0.059 13.6 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5379) Fumarate_red_D PF02313.17 CBY09177.1 - 4.5 7.4 8.1 0.41 10.8 0.5 2.7 2 1 0 2 2 2 0 Fumarate reductase subunit D Siva PF05458.12 CBY09179.1 - 0.028 14.1 7.8 0.058 13.1 7.8 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FOXP-CC PF16159.5 CBY09179.1 - 0.088 13.5 0.1 0.088 13.5 0.1 3.1 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-HC5HC2H PF13771.6 CBY09179.1 - 1.1 9.6 10.5 5.6 7.3 10.5 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain TMCO5 PF14992.6 CBY09179.1 - 4.8 6.7 15.3 0.34 10.5 7.1 2.2 1 1 1 2 2 2 0 TMCO5 family Prok-RING_1 PF14446.6 CBY09179.1 - 6.4 6.8 11.3 19 5.3 11.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RecR PF02132.15 CBY09179.1 - 7.1 6.3 9.7 1.3 8.7 1.1 2.5 1 1 1 2 2 2 0 RecR protein Prok-RING_4 PF14447.6 CBY09179.1 - 7.5 6.5 10.5 16 5.5 10.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FerB PF08150.12 CBY09180.1 - 0.059 14.0 0.1 0.16 12.6 0.1 1.6 1 0 0 1 1 1 0 FerB (NUC096) domain EGF PF00008.27 CBY09181.1 - 1.3e-14 54.2 46.7 1.8e-06 28.1 2.7 4.7 3 1 2 5 5 5 3 EGF-like domain EGF_CA PF07645.15 CBY09181.1 - 3e-13 49.7 26.6 1.8e-09 37.6 6.1 4.4 2 2 2 4 4 4 2 Calcium-binding EGF domain EGF_2 PF07974.13 CBY09181.1 - 4.3e-12 46.2 57.6 0.0001 22.6 9.2 4.2 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 CBY09181.1 - 1.6e-07 31.7 53.2 7.3e-05 23.2 6.6 5.9 6 0 0 6 6 6 3 Human growth factor-like EGF EGF_3 PF12947.7 CBY09181.1 - 1.4e-06 28.4 38.6 0.00033 20.8 2.0 5.5 2 2 3 5 5 5 3 EGF domain Laminin_EGF PF00053.24 CBY09181.1 - 0.79 9.9 44.7 1.9 8.7 5.8 4.4 2 1 2 4 4 4 0 Laminin EGF domain Pepdidase_M14_N PF18027.1 CBY09182.1 - 3.7e-18 65.9 0.3 1e-17 64.5 0.3 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 CBY09182.1 - 3.9e-15 56.4 0.8 2.7e-14 53.7 0.0 2.6 2 1 0 2 2 2 1 Zinc carboxypeptidase Creb_binding PF09030.10 CBY09182.1 - 3.4 8.4 6.7 0.17 12.6 0.3 2.2 2 1 0 2 2 2 0 Creb binding FAM104 PF15434.6 CBY09183.1 - 2.6 8.6 7.3 2 9.0 1.8 2.2 2 0 0 2 2 2 0 Family 104 B56 PF01603.20 CBY09184.1 - 2.4e-188 626.3 4.7 2.8e-188 626.1 4.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CBY09184.1 - 0.0034 17.3 2.2 0.13 12.1 0.2 2.7 2 1 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal MATH PF00917.26 CBY09185.1 - 2.6e-07 30.8 0.2 6.9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 MATH domain zf-RING_2 PF13639.6 CBY09185.1 - 2e-06 28.0 15.4 2e-06 28.0 15.4 3.9 5 0 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY09185.1 - 3.5e-06 26.8 15.1 3.5e-06 26.8 15.1 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 CBY09185.1 - 0.00016 21.7 11.1 0.00016 21.7 11.1 2.9 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.6 CBY09185.1 - 0.00092 19.0 15.1 0.00092 19.0 15.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Cep57_MT_bd PF06657.13 CBY09185.1 - 0.025 15.0 1.4 0.025 15.0 1.4 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Exo_endo_phos PF03372.23 CBY09188.1 - 1.8e-20 73.4 0.0 2.3e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CBY09188.1 - 0.012 15.4 0.3 0.028 14.3 0.3 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase XRCC4 PF06632.12 CBY09188.1 - 1.7 7.4 10.7 3 6.6 10.7 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ndc1_Nup PF09531.10 CBY09188.1 - 3 6.4 4.6 3.2 6.3 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRF-TF PF00319.18 CBY09189.1 - 1.4e-19 69.3 0.2 2.1e-19 68.7 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SRF-TF PF00319.18 CBY09190.1 - 1.2e-18 66.3 0.0 2.3e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribonuc_L-PSP PF01042.21 CBY09191.1 - 3.4e-44 149.7 0.4 4e-44 149.5 0.4 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 CBY09191.1 - 0.0081 16.3 0.0 0.016 15.4 0.0 1.6 1 1 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Pkinase PF00069.25 CBY09192.1 - 6.1e-45 153.6 0.0 1e-44 152.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09192.1 - 7e-38 130.4 0.0 1e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY09192.1 - 0.17 10.6 0.0 0.17 10.6 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase Pkinase PF00069.25 CBY09193.1 - 1.1e-41 143.0 0.0 1.6e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09193.1 - 1.5e-31 109.6 0.0 2.4e-31 108.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY09193.1 - 0.004 16.0 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CBY09193.1 - 0.01 14.8 0.2 0.016 14.2 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4486 PF14858.6 CBY09193.1 - 0.034 12.7 0.0 0.05 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) YrbL-PhoP_reg PF10707.9 CBY09193.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL bZIP_1 PF00170.21 CBY09194.1 - 0.067 13.3 3.4 0.14 12.3 3.4 1.6 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 CBY09194.1 - 0.088 12.9 3.9 0.13 12.3 3.9 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Pkinase PF00069.25 CBY09195.1 - 9.3e-23 80.9 0.0 9.4e-22 77.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09195.1 - 3e-22 79.2 0.1 1.4e-21 77.0 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2153 PF09921.9 CBY09195.1 - 0.14 12.0 2.8 0.31 10.9 1.8 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) DUF848 PF05852.11 CBY09195.1 - 1.9 8.6 5.9 5.4 7.1 0.0 3.1 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) TPR_12 PF13424.6 CBY09196.1 - 1.7e-05 25.0 0.9 0.12 12.7 0.1 3.7 2 2 2 4 4 4 3 Tetratricopeptide repeat DUF410 PF04190.13 CBY09196.1 - 4.5e-05 23.4 0.5 7.1e-05 22.7 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF410) TPR_10 PF13374.6 CBY09196.1 - 0.00014 21.6 1.7 0.014 15.2 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY09196.1 - 0.00016 21.5 0.6 0.22 11.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY09196.1 - 0.00023 21.0 5.2 0.2 11.9 0.1 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC5 PF12862.7 CBY09196.1 - 0.0036 17.3 0.2 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 CBY09196.1 - 0.0048 16.3 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 MalT-like TPR region SKI PF01202.22 CBY09196.1 - 0.018 15.2 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate kinase Hairy_orange PF07527.13 CBY09196.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Hairy Orange Myb_CC_LHEQLE PF14379.6 CBY09196.1 - 0.17 11.6 1.0 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif ATP-synt_S1 PF05827.12 CBY09197.1 - 4.5e-09 36.3 0.0 7.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PTP_tm PF18861.1 CBY09197.1 - 0.0012 18.9 0.4 0.0018 18.3 0.4 1.4 1 1 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Lamp PF01299.17 CBY09197.1 - 0.0016 18.3 0.0 0.0027 17.6 0.0 1.4 1 1 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Ank_4 PF13637.6 CBY09198.1 - 7.3e-07 29.6 0.0 0.054 14.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY09198.1 - 1.7e-06 28.5 0.2 7.9e-06 26.4 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY09198.1 - 0.00021 21.5 0.1 0.0006 20.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY09198.1 - 0.0012 19.2 0.6 0.62 10.6 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat AT_hook PF02178.19 CBY09198.1 - 6.7 7.0 22.8 7.2 6.9 7.9 3.0 2 0 0 2 2 2 0 AT hook motif Peptidase_M44 PF03410.13 CBY09199.1 - 0.35 9.4 3.1 0.52 8.8 3.1 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox Frizzled PF01534.17 CBY09200.1 - 4.5e-122 407.1 19.2 6.5e-122 406.6 19.2 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CBY09200.1 - 2e-19 70.2 8.1 2e-19 70.2 8.1 1.8 2 0 0 2 2 2 1 Fz domain Ndc1_Nup PF09531.10 CBY09200.1 - 0.0014 17.4 2.3 0.0024 16.7 2.3 1.4 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF898 PF05987.13 CBY09200.1 - 0.014 14.5 0.1 0.014 14.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) PRRSV_2b PF07069.11 CBY09200.1 - 1.5 9.4 5.4 8.4 7.0 0.3 2.6 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Vma12 PF11712.8 CBY09201.1 - 0.0064 16.6 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2786 PF10979.8 CBY09201.1 - 0.044 13.7 1.4 0.086 12.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Consortin_C PF15281.6 CBY09201.1 - 0.084 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Consortin C-terminus SH3_1 PF00018.28 CBY09203.1 - 3e-15 55.6 0.1 1.9e-14 53.0 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CBY09203.1 - 1.6e-11 43.8 0.0 6.2e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CBY09203.1 - 3.7e-09 36.1 0.0 3.8e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain C1_1 PF00130.22 CBY09203.1 - 3.8e-09 36.3 2.0 8.2e-09 35.2 2.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CBY09203.1 - 0.28 11.3 2.7 1.4 9.0 2.7 2.2 1 1 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 CBY09203.1 - 3.7 7.2 6.2 8.4 6.1 1.1 2.7 3 0 0 3 3 3 0 PHD-finger zf-RING-like PF08746.11 CBY09203.1 - 6.3 7.2 7.2 0.36 11.2 1.5 1.8 2 0 0 2 2 2 0 RING-like domain Pkinase_Tyr PF07714.17 CBY09204.1 - 6.3e-66 222.3 0.0 1.1e-65 221.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY09204.1 - 6.5e-28 97.8 0.0 1.1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Fz PF01392.22 CBY09204.1 - 7.4e-09 36.2 8.9 2e-08 34.8 8.9 1.8 1 0 0 1 1 1 1 Fz domain Kringle PF00051.18 CBY09204.1 - 1.3e-07 31.8 3.5 2e-07 31.2 1.6 2.5 2 0 0 2 2 2 1 Kringle domain I-set PF07679.16 CBY09204.1 - 5.3e-06 26.4 0.2 1.1e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY09204.1 - 0.0021 18.6 0.7 0.0071 16.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Haspin_kinase PF12330.8 CBY09204.1 - 0.011 14.8 0.0 0.027 13.4 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Pox_P21 PF05313.12 CBY09204.1 - 0.11 12.1 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein I_LWEQ PF01608.17 CBY09205.1 - 2.7e-68 229.0 207.7 4.6e-39 134.1 9.8 25.9 13 7 13 27 27 27 17 I/LWEQ domain FERM_M PF00373.18 CBY09205.1 - 2.8e-15 56.8 0.3 2.8e-15 56.8 0.3 3.5 3 0 0 3 3 3 1 FERM central domain Talin_middle PF09141.10 CBY09205.1 - 1.7e-09 37.9 1.6 1.7e-09 37.9 1.6 21.2 13 7 6 20 20 19 3 Talin, middle domain HCMV_UL139 PF12507.8 CBY09205.1 - 1.9e-06 28.2 1.9 0.067 13.6 0.2 4.4 3 0 0 3 3 3 2 Human Cytomegalovirus UL139 protein DUF1296 PF06972.11 CBY09205.1 - 0.0019 18.3 6.7 7.7 6.7 0.0 5.9 4 0 0 4 4 3 2 Protein of unknown function (DUF1296) FERM_N PF09379.10 CBY09205.1 - 0.0023 17.8 3.2 0.0064 16.4 0.4 2.9 2 0 0 2 2 2 1 FERM N-terminal domain VBS PF08913.10 CBY09205.1 - 0.003 18.0 14.8 0.0048 17.3 3.6 13.4 14 2 2 16 16 16 3 Vinculin Binding Site Rad60-SLD PF11976.8 CBY09205.1 - 0.019 14.8 4.1 0.032 14.1 2.0 2.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2205 PF10224.9 CBY09205.1 - 0.053 13.5 1.0 5.3 7.1 0.3 5.0 3 0 0 3 3 3 0 Short coiled-coil protein Snapin_Pallidin PF14712.6 CBY09205.1 - 0.058 13.8 38.0 0.076 13.4 1.9 9.3 8 0 0 8 8 7 0 Snapin/Pallidin PhoU_div PF01865.16 CBY09205.1 - 0.75 9.1 13.7 3.9 6.7 0.1 5.8 5 1 0 5 5 5 0 Protein of unknown function DUF47 DUF2383 PF09537.10 CBY09205.1 - 1.1 9.6 18.3 1.5 9.2 0.1 6.7 6 2 2 8 8 7 0 Domain of unknown function (DUF2383) RtcB PF01139.17 CBY09206.1 - 5e-150 500.2 0.1 5.7e-150 500.1 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Docking PF08990.11 CBY09207.1 - 0.059 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking Acetyltransf_1 PF00583.25 CBY09208.1 - 6.8e-13 48.9 0.0 8.9e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY09208.1 - 4.5e-10 39.6 0.0 6.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY09208.1 - 2.3e-09 37.1 0.0 3.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CBY09208.1 - 1.1e-08 35.3 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY09208.1 - 6.6e-05 23.1 0.3 0.00011 22.4 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY09208.1 - 0.00028 21.0 0.1 0.00043 20.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-CCHC PF00098.23 CBY09209.1 - 4.6e-07 29.6 18.7 0.00067 19.6 0.9 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 CBY09209.1 - 0.00054 19.7 16.7 0.018 14.9 1.5 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 CBY09209.1 - 0.0031 17.2 14.6 0.042 13.6 0.4 3.3 3 0 0 3 3 3 2 Zinc knuckle PHD_4 PF16866.5 CBY09209.1 - 0.095 12.8 8.1 0.17 12.0 1.4 2.4 1 1 1 2 2 2 0 PHD-finger ThiC_Rad_SAM PF01964.18 CBY09209.1 - 4.7 5.9 6.2 1.8 7.2 3.9 1.5 1 1 1 2 2 2 0 Radical SAM ThiC family Ribosomal_L10 PF00466.20 CBY09212.1 - 3e-17 62.6 1.8 3.3e-17 62.4 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 CBY09212.1 - 3e-15 56.0 0.0 4.8e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P DUF349 PF03993.12 CBY09212.1 - 0.098 13.0 0.3 0.32 11.3 0.3 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Maf1 PF09174.10 CBY09213.1 - 1.8e-46 158.5 0.2 2.3e-46 158.1 0.2 1.1 1 0 0 1 1 1 1 Maf1 regulator FoP_duplication PF13865.6 CBY09214.1 - 0.0015 19.1 1.3 0.0026 18.2 1.3 1.6 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RGS-like PF09128.11 CBY09214.1 - 0.13 12.0 5.4 0.23 11.1 5.4 1.4 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain VKG_Carbox PF05090.14 CBY09215.1 - 1.8e-131 439.0 19.2 2.3e-131 438.6 19.2 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Hum_adeno_E3A PF05393.11 CBY09215.1 - 0.014 15.3 0.3 0.033 14.2 0.3 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein PAC2 PF09754.9 CBY09217.1 - 7.7e-12 45.7 0.0 8.7e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 PAC2 family CUT PF02376.15 CBY09217.1 - 0.096 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 CUT domain MarC PF01914.17 CBY09219.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 MarC family integral membrane protein Mucin PF01456.17 CBY09220.1 - 0.12 12.4 17.7 0.22 11.5 17.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 CBY09220.1 - 0.28 11.1 7.6 0.59 10.1 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Scramblase PF03803.15 CBY09221.1 - 2e-23 82.9 0.0 2.8e-22 79.1 0.0 2.0 1 1 0 1 1 1 1 Scramblase Cauli_VI PF01693.16 CBY09222.1 - 1.5e-08 34.8 0.1 1.5e-08 34.8 0.1 2.0 2 0 0 2 2 2 1 Caulimovirus viroplasmin DnaJ PF00226.31 CBY09222.1 - 2.3e-06 27.6 0.1 7.9e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain Flavokinase PF01687.17 CBY09223.1 - 2.4e-12 47.2 0.0 2.7e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase DAP3 PF10236.9 CBY09224.1 - 9.7e-31 107.1 0.0 5.1e-11 42.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 CBY09224.1 - 0.0011 18.9 0.1 0.0024 17.8 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CBY09224.1 - 0.0034 17.8 0.0 0.014 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY09224.1 - 0.013 15.7 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBY09224.1 - 0.025 14.5 0.1 0.061 13.2 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 CBY09224.1 - 0.025 15.0 0.0 0.21 12.0 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Cytochrom_C PF00034.21 CBY09224.1 - 0.03 15.5 0.4 28 5.9 0.0 3.1 3 1 0 3 3 3 0 Cytochrome c NB-ARC PF00931.22 CBY09224.1 - 0.061 12.5 0.1 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 CBY09224.1 - 0.073 13.1 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain sCache_3_2 PF17203.4 CBY09224.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Single cache domain 3 Isochorismatase PF00857.20 CBY09224.1 - 0.15 12.2 0.2 19 5.4 0.0 2.9 3 0 0 3 3 3 0 Isochorismatase family zf-C3HC4 PF00097.25 CBY09225.1 - 1.2e-10 41.0 8.7 1.7e-10 40.6 8.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY09225.1 - 5.7e-10 38.9 5.8 7.9e-10 38.4 5.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY09225.1 - 8.9e-10 38.3 10.6 1.3e-09 37.8 10.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY09225.1 - 4.7e-09 36.4 10.4 6.3e-09 36.0 10.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY09225.1 - 4e-08 33.2 8.0 3e-07 30.3 8.4 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY09225.1 - 1.1e-06 28.5 7.7 1.5e-06 28.0 7.7 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY09225.1 - 1.4e-06 28.1 7.0 2e-06 27.5 7.0 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CBY09225.1 - 2.6e-06 27.5 9.0 3.9e-06 26.9 9.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBY09225.1 - 2.5e-05 24.5 8.7 4e-05 23.8 8.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY09225.1 - 9.2e-05 22.4 3.5 0.00014 21.9 3.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 CBY09225.1 - 0.0017 18.3 3.0 0.0027 17.7 3.0 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 CBY09225.1 - 0.011 15.6 2.1 0.019 14.9 2.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 CBY09225.1 - 0.13 11.9 5.1 0.19 11.4 5.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 CBY09225.1 - 0.15 11.4 0.2 0.22 10.8 0.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_4 PF14570.6 CBY09225.1 - 0.72 9.7 8.6 1.5 8.7 8.3 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CBY09225.1 - 0.81 9.5 7.9 1 9.2 4.3 2.4 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 CBY09225.1 - 0.95 9.6 5.8 1.6 8.9 5.8 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 CBY09225.1 - 2.3 8.5 8.8 5.3 7.3 3.8 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain PhaP_Bmeg PF09602.10 CBY09226.1 - 0.022 14.7 2.9 0.13 12.2 0.6 2.4 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1090 PF06476.12 CBY09226.1 - 1.9 8.6 13.2 15 5.7 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1090) JHY PF15261.6 CBY09226.1 - 3 8.6 12.8 0.38 11.4 0.5 3.0 2 1 1 3 3 3 0 Jhy protein DUF4647 PF15504.6 CBY09227.1 - 0.092 11.8 3.3 0.2 10.7 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) SBF PF01758.16 CBY09228.1 - 5.2e-19 68.7 18.0 5.2e-19 68.7 18.0 2.0 1 1 1 2 2 2 1 Sodium Bile acid symporter family DUF1282 PF06930.12 CBY09228.1 - 0.41 10.4 20.5 0.81 9.4 18.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) LLC1 PF14945.6 CBY09229.1 - 3.3e-10 40.6 6.6 6.3e-06 26.8 1.4 2.1 1 1 1 2 2 2 2 Normal lung function maintenance, Low in Lung Cancer 1 protein TCRP1 PF14944.6 CBY09230.1 - 0.00046 20.2 3.1 0.00077 19.5 3.1 1.3 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 Forkhead PF00250.18 CBY09231.1 - 1.2e-36 124.9 0.0 1.8e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain DUF4365 PF14280.6 CBY09232.1 - 0.034 14.1 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) DZF PF07528.14 CBY09233.1 - 3.2e-17 63.0 0.2 2.3e-16 60.2 0.0 2.3 2 1 0 2 2 2 1 DZF domain dsrm PF00035.26 CBY09233.1 - 0.0074 17.0 0.0 0.021 15.5 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif CitX PF03802.14 CBY09233.1 - 0.038 13.8 1.4 0.15 11.8 0.3 2.3 1 1 1 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase RF-1 PF00472.20 CBY09233.1 - 7.8 6.5 10.3 0.19 11.7 0.6 2.7 2 1 0 2 2 2 0 RF-1 domain SecA_DEAD PF07517.14 CBY09235.1 - 4 6.6 7.5 2.2 7.5 0.4 2.4 2 0 0 2 2 2 0 SecA DEAD-like domain Kinesin PF00225.23 CBY09236.1 - 1.3e-86 290.6 0.1 1.3e-86 290.6 0.1 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY09236.1 - 1.5e-19 70.4 0.0 2.4e-18 66.5 0.0 3.0 2 0 0 2 2 2 1 Microtubule binding PRKG1_interact PF15898.5 CBY09236.1 - 0.67 10.9 39.9 0.83 10.6 14.6 3.7 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF2228 PF10228.9 CBY09236.1 - 2.1 8.0 13.8 0.13 12.0 0.8 3.3 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2228) AAA_16 PF13191.6 CBY09236.1 - 8.2 6.8 9.5 0.65 10.4 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain IFRD PF05004.13 CBY09237.1 - 0.0044 16.2 0.1 0.0048 16.0 0.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Sec7_N PF12783.7 CBY09237.1 - 0.031 14.2 0.2 0.059 13.3 0.3 1.4 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1415 PF07209.12 CBY09237.1 - 0.14 11.9 0.1 0.15 11.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) zf-HC5HC2H_2 PF13832.6 CBY09238.1 - 1.4e-06 28.5 2.1 2.4e-06 27.7 2.1 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBY09238.1 - 5.9e-06 26.4 3.9 1.2e-05 25.5 3.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.29 CBY09238.1 - 0.0091 15.9 6.3 0.025 14.4 6.3 1.8 1 0 0 1 1 1 1 PHD-finger Rubredoxin PF00301.20 CBY09238.1 - 0.045 13.8 0.1 0.15 12.1 0.1 1.9 1 0 0 1 1 1 0 Rubredoxin FANCL_C PF11793.8 CBY09238.1 - 0.15 12.3 6.0 0.21 11.8 5.0 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain C1_2 PF03107.16 CBY09238.1 - 0.61 10.4 6.5 0.21 11.9 2.0 2.3 2 0 0 2 2 2 0 C1 domain zf-rbx1 PF12678.7 CBY09238.1 - 3 8.2 7.5 9.6 6.6 7.5 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 CBY09238.1 - 4.7 7.6 7.8 1.8 8.9 3.1 2.8 3 1 0 3 3 3 0 RING-like domain Peptidase_M17 PF00883.21 CBY09239.1 - 2.6e-63 214.2 0.1 3.8e-63 213.7 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain RNase_P_p30 PF01876.16 CBY09240.1 - 4.5e-40 137.4 0.0 5.4e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Ank_4 PF13637.6 CBY09241.1 - 0.00089 19.8 0.2 0.71 10.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY09241.1 - 0.009 16.3 0.1 0.051 13.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY09241.1 - 0.085 13.5 0.2 2 9.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) DUF4094 PF13334.6 CBY09242.1 - 0.0054 17.1 12.5 0.012 16.0 1.3 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4094) DUF4590 PF15257.6 CBY09242.1 - 0.034 14.1 1.0 0.074 13.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) CENP-F_leu_zip PF10473.9 CBY09242.1 - 0.16 12.0 37.1 0.39 10.7 16.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PEX11 PF05648.14 CBY09242.1 - 0.27 10.7 4.4 0.92 8.9 4.3 2.2 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF1664 PF07889.12 CBY09242.1 - 0.28 11.2 11.3 0.88 9.6 2.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 CBY09242.1 - 0.3 11.5 14.8 1.7 9.0 0.8 3.8 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4164 PF13747.6 CBY09242.1 - 0.52 10.6 19.4 0.13 12.5 5.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) ATPase PF06745.13 CBY09242.1 - 0.94 8.8 8.0 0.59 9.4 4.7 2.3 1 1 0 2 2 2 0 KaiC LMBR1 PF04791.16 CBY09242.1 - 1.3 7.8 8.0 1.8 7.4 8.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF724 PF05266.14 CBY09242.1 - 4.6 7.0 25.1 4.9 6.9 8.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF4404 PF14357.6 CBY09242.1 - 7.5 7.3 15.4 1.1 9.9 8.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) CytochromB561_N PF09786.9 CBY09243.1 - 1.1e-34 120.4 3.9 2e-34 119.6 3.4 1.7 1 1 0 1 1 1 1 Cytochrome B561, N terminal V-ATPase_C PF03223.15 CBY09244.1 - 5e-123 411.2 0.0 5.7e-123 411.0 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C TFIIA PF03153.13 CBY09245.1 - 6.3e-19 69.3 14.8 9.8e-19 68.6 14.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Got1 PF04178.12 CBY09246.1 - 4.5e-29 101.1 10.5 5.9e-29 100.8 10.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family JmjC PF02373.22 CBY09247.1 - 7.3e-37 126.3 0.1 1.7e-36 125.1 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CBY09247.1 - 1e-11 44.6 0.3 3e-11 43.1 0.3 1.9 1 0 0 1 1 1 1 jmjN domain EF-hand_7 PF13499.6 CBY09248.1 - 1.7e-06 28.4 4.1 3.2e-05 24.3 0.3 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY09248.1 - 3.2e-06 26.6 0.3 0.13 12.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY09248.1 - 0.0099 15.4 0.0 0.24 11.0 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CBY09248.1 - 0.04 13.4 0.2 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 EF hand YlqD PF11068.8 CBY09250.1 - 0.0069 16.8 4.1 0.008 16.6 4.1 1.1 1 0 0 1 1 1 1 YlqD protein Synaphin PF05835.12 CBY09250.1 - 0.17 12.1 7.8 0.19 12.0 7.8 1.1 1 0 0 1 1 1 0 Synaphin protein EF-hand_13 PF17958.1 CBY09251.1 - 0.019 14.8 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain SPT_ssu-like PF11779.8 CBY09253.1 - 5.6e-09 35.5 5.5 6.8e-09 35.2 5.5 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF842 PF05811.13 CBY09254.1 - 4.7e-11 42.5 5.6 6.2e-11 42.1 5.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) WD40 PF00400.32 CBY09255.1 - 1.7e-31 107.8 9.6 6.2e-07 30.0 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Prp19 PF08606.11 CBY09255.1 - 9.3e-18 64.0 0.8 1.9e-17 63.0 0.8 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 CBY09255.1 - 3.5e-14 52.9 0.6 0.00058 20.1 0.0 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY09255.1 - 9.7e-08 31.1 2.8 0.00052 18.8 0.4 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 U-box PF04564.15 CBY09255.1 - 2.8e-05 24.2 0.0 6.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 CBY09255.1 - 0.00052 19.1 0.0 0.011 14.7 0.0 3.0 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBY09255.1 - 0.0057 16.0 0.0 0.1 11.9 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain zf-NOSIP PF15906.5 CBY09255.1 - 0.03 14.4 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein tRNA_bind_2 PF13725.6 CBY09255.1 - 0.033 13.9 1.9 0.05 13.3 1.9 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain SYF2 PF08231.12 CBY09255.1 - 0.25 11.7 4.1 0.55 10.6 4.1 1.5 1 0 0 1 1 1 0 SYF2 splicing factor DUF2514 PF10721.9 CBY09255.1 - 0.58 10.2 5.1 1 9.3 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) UPF0449 PF15136.6 CBY09255.1 - 0.62 10.6 3.8 0.62 10.6 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Pkinase PF00069.25 CBY09256.1 - 7.6e-06 25.5 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09256.1 - 0.00012 21.5 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PI3_PI4_kinase PF00454.27 CBY09258.1 - 1.1e-48 166.2 0.0 1.3e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF5315 PF17242.2 CBY09258.1 - 0.16 11.8 0.2 0.35 10.7 0.2 1.5 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) EST1_DNA_bind PF10373.9 CBY09259.1 - 1.5e-20 73.9 1.0 1.3e-15 57.6 0.0 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.9 CBY09259.1 - 1e-10 42.4 0.5 4.1e-10 40.4 0.5 2.2 1 0 0 1 1 1 1 Telomerase activating protein Est1 PIN_4 PF13638.6 CBY09259.1 - 5e-10 39.8 4.7 6.1e-10 39.5 3.0 2.1 2 0 0 2 2 2 1 PIN domain PIN PF01850.21 CBY09259.1 - 0.051 14.1 0.3 0.42 11.1 0.2 2.5 2 0 0 2 2 2 0 PIN domain PIN_9 PF18477.1 CBY09259.1 - 0.079 13.3 3.0 0.52 10.6 3.0 2.3 1 1 0 1 1 1 0 PIN like domain DUF4972 PF16342.5 CBY09261.1 - 0.21 11.2 4.6 0.26 11.0 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) B277 PF17623.2 CBY09261.1 - 0.24 10.4 10.3 0.28 10.2 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function CCDC66 PF15236.6 CBY09261.1 - 1.1 9.0 22.3 1.7 8.4 22.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF4407 PF14362.6 CBY09261.1 - 1.7 8.0 8.0 2 7.7 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3987 PF13148.6 CBY09261.1 - 2 7.3 8.7 2.5 7.0 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_23 PF13476.6 CBY09261.1 - 2.6 8.5 15.4 3 8.3 15.4 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 CBY09261.1 - 3.3 5.5 6.4 3.6 5.4 6.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec62 PF03839.16 CBY09261.1 - 7.8 5.9 8.4 9.4 5.7 8.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ribosomal_L34e PF01199.18 CBY09263.1 - 3.6e-39 133.0 3.7 4.4e-39 132.7 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e DUF2873 PF11395.8 CBY09264.1 - 0.033 14.0 0.4 0.034 14.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) TFIIS_C PF01096.18 CBY09265.1 - 2.1e-12 46.7 4.4 2.1e-12 46.7 4.4 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 CBY09265.1 - 0.0027 17.6 9.9 1.2 9.1 0.1 3.2 3 0 0 3 3 3 2 zinc-ribbon domain zf-3CxxC PF13695.6 CBY09265.1 - 0.028 14.9 3.7 0.051 14.0 0.2 2.0 2 0 0 2 2 2 0 Zinc-binding domain DUF3268 PF11672.8 CBY09265.1 - 0.041 14.2 1.7 0.079 13.3 1.7 1.4 1 0 0 1 1 1 0 zinc-finger-containing domain Tnp_zf-ribbon_2 PF13842.6 CBY09265.1 - 0.056 14.3 9.6 9 7.2 0.1 3.2 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon PH_17 PF18012.1 CBY09265.1 - 0.12 12.1 0.4 0.18 11.6 0.1 1.5 2 0 0 2 2 2 0 PH domain NCD3G PF07562.14 CBY09265.1 - 0.14 12.2 0.5 0.14 12.2 0.5 2.9 3 1 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR DNA_RNApol_7kD PF03604.13 CBY09265.1 - 0.47 10.2 6.9 4.5 7.0 0.2 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.6 CBY09265.1 - 0.52 10.1 10.4 6.8 6.5 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Baculo_LEF5_C PF11792.8 CBY09265.1 - 0.53 10.0 6.5 3.9 7.2 6.5 2.2 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Zn-ribbon_8 PF09723.10 CBY09265.1 - 0.93 9.7 9.2 2.9 8.1 0.3 2.9 3 0 0 3 3 3 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 CBY09265.1 - 1.1 9.0 9.1 9.6 6.0 0.1 3.2 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf_UBZ PF18439.1 CBY09265.1 - 1.4 8.6 0.0 1.4 8.6 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger RecR PF02132.15 CBY09265.1 - 3.6 7.2 9.5 2.7 7.6 0.3 2.8 3 0 0 3 3 3 0 RecR protein Voltage_CLC PF00654.20 CBY09266.1 - 7.5e-95 318.2 24.6 1.8e-94 316.9 22.6 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBY09266.1 - 3.3e-05 24.2 1.0 0.0013 19.2 0.2 2.5 2 0 0 2 2 2 1 CBS domain Sds3 PF08598.11 CBY09267.1 - 0.00042 20.4 15.8 0.00042 20.4 15.8 1.7 2 1 0 2 2 2 1 Sds3-like Phospholip_A2_1 PF00068.19 CBY09268.1 - 1.5e-11 44.7 5.6 2.7e-11 43.9 5.6 1.4 1 0 0 1 1 1 1 Phospholipase A2 Ion_trans PF00520.31 CBY09269.1 - 3.1e-41 141.2 16.1 3.9e-41 140.9 16.1 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CBY09269.1 - 4.6e-17 62.2 0.4 2.2e-16 60.0 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 CBY09269.1 - 4.4e-15 55.4 4.1 4.4e-15 55.4 4.1 2.7 2 1 1 3 3 3 1 Ion channel PKD_channel PF08016.12 CBY09269.1 - 0.001 17.9 11.5 0.0011 17.7 2.1 2.7 2 1 1 3 3 3 2 Polycystin cation channel Lig_chan PF00060.26 CBY09269.1 - 0.076 12.9 3.0 0.45 10.3 0.5 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel Chromate_transp PF02417.15 CBY09269.1 - 2 8.6 9.6 0.75 9.9 1.2 2.5 2 1 1 3 3 3 0 Chromate transporter DUF1836 PF08876.11 CBY09270.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) Peptidase_S49_N PF08496.10 CBY09270.1 - 0.14 12.2 0.3 0.26 11.3 0.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_23 PF13476.6 CBY09272.1 - 1.6 9.2 9.7 0.076 13.5 2.4 2.4 2 1 0 2 2 2 0 AAA domain STN PF07660.14 CBY09273.1 - 0.0085 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain DUF2058 PF09831.9 CBY09273.1 - 0.11 12.6 2.2 0.13 12.4 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) ScsC_N PF18312.1 CBY09273.1 - 0.16 11.8 0.5 3.3 7.6 0.3 2.5 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain DUF1002 PF06207.11 CBY09273.1 - 0.21 11.1 1.9 0.27 10.7 1.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) BTD PF09270.10 CBY09274.1 - 7.5e-65 217.8 0.0 1.2e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 CBY09274.1 - 3.3e-09 37.5 1.0 5.7e-09 36.8 0.1 1.9 2 0 0 2 2 2 1 LAG1, DNA binding Ins145_P3_rec PF08709.11 CBY09274.1 - 0.056 12.6 0.1 0.68 9.1 0.1 2.4 1 1 1 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Cyclin_N PF00134.23 CBY09276.1 - 1.2e-38 131.7 0.9 2.1e-38 130.9 0.9 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Acyl_transf_3 PF01757.22 CBY09277.1 - 0.00035 19.7 2.0 0.00039 19.6 2.0 1.1 1 0 0 1 1 1 1 Acyltransferase family EGF_CA PF07645.15 CBY09278.1 - 6.2e-09 35.9 6.3 6.2e-09 35.9 6.3 4.7 6 1 0 6 6 6 1 Calcium-binding EGF domain cEGF PF12662.7 CBY09278.1 - 2.6e-05 24.0 16.6 4.3e-05 23.4 0.3 3.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like SEA PF01390.20 CBY09278.1 - 0.00038 20.5 0.0 0.00068 19.7 0.0 1.4 1 0 0 1 1 1 1 SEA domain EGF_3 PF12947.7 CBY09278.1 - 0.0004 20.5 19.5 0.00076 19.6 5.6 3.5 3 0 0 3 3 3 2 EGF domain Plasmod_Pvs28 PF06247.11 CBY09278.1 - 0.014 15.7 4.0 0.014 15.7 4.0 4.6 4 1 0 4 4 4 0 Pvs28 EGF domain hEGF PF12661.7 CBY09278.1 - 0.049 14.3 10.1 0.34 11.6 2.0 3.8 3 1 0 3 3 3 0 Human growth factor-like EGF EGF PF00008.27 CBY09278.1 - 0.17 12.2 22.0 0.29 11.5 8.5 3.2 3 0 0 3 3 3 0 EGF-like domain AMP-binding PF00501.28 CBY09279.1 - 1.9e-48 165.2 0.0 2.2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY09279.1 - 9.4e-05 23.3 0.0 0.00017 22.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain bZIP_Maf PF03131.17 CBY09280.1 - 2e-06 28.2 8.2 2e-06 28.2 8.2 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.21 CBY09280.1 - 0.0004 20.4 10.3 0.001 19.1 9.4 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY09280.1 - 0.00069 19.7 9.1 0.0025 17.9 9.1 2.0 1 1 0 1 1 1 1 Basic region leucine zipper NBP1 PF08537.10 CBY09280.1 - 0.0096 15.4 3.9 0.0096 15.4 3.9 1.6 2 0 0 2 2 2 1 Fungal Nap binding protein NBP1 LTXXQ PF07813.12 CBY09280.1 - 0.11 13.3 5.3 0.33 11.7 5.3 1.9 1 1 0 1 1 1 0 LTXXQ motif family protein DUF2559 PF10832.8 CBY09280.1 - 0.14 12.2 1.3 7.2 6.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) Spc7 PF08317.11 CBY09280.1 - 0.71 8.7 15.3 0.036 13.0 6.0 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein UNC-93 PF05978.16 CBY09284.1 - 1.6e-22 79.9 7.9 1.6e-22 79.9 7.9 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 SOAR PF16533.5 CBY09284.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF443 PF04276.12 CBY09284.1 - 0.51 10.1 3.8 0.29 10.9 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF443) zf-C3Hc3H PF13891.6 CBY09285.1 - 0.051 13.9 0.2 0.063 13.7 0.2 1.3 1 0 0 1 1 1 0 Potential DNA-binding domain EGF_CA PF07645.15 CBY09286.1 - 2.1e-183 594.3 422.8 1.3e-10 41.3 10.3 28.3 26 2 3 29 29 29 23 Calcium-binding EGF domain EGF_3 PF12947.7 CBY09286.1 - 8.8e-133 432.2 397.3 1.8e-08 34.4 7.2 27.7 27 0 0 27 27 27 27 EGF domain cEGF PF12662.7 CBY09286.1 - 1e-86 284.3 271.1 4.1e-08 33.0 5.3 29.2 28 0 0 28 28 28 24 Complement Clr-like EGF-like EGF PF00008.27 CBY09286.1 - 3.7e-48 161.4 341.0 2.7e-05 24.4 6.6 28.7 28 0 0 28 28 28 23 EGF-like domain hEGF PF12661.7 CBY09286.1 - 1.2e-46 155.8 276.4 0.00011 22.7 7.1 30.1 27 0 0 27 27 27 22 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY09286.1 - 4.4e-34 116.2 337.2 2.1e-05 24.5 6.0 27.1 27 0 0 27 27 27 19 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY09286.1 - 2.5e-16 59.6 353.9 0.015 15.5 6.3 28.2 17 8 10 27 27 27 16 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY09286.1 - 1e-05 25.7 308.0 0.0017 18.6 3.6 26.3 24 3 1 25 25 25 15 Pvs28 EGF domain Telomere_Sde2_2 PF13297.6 CBY09287.1 - 3.7e-22 77.7 0.4 3.7e-22 77.7 0.4 2.0 2 0 0 2 2 2 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 CBY09287.1 - 3.9e-11 43.1 1.1 3.9e-11 43.1 1.1 1.9 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain RhoGAP PF00620.27 CBY09288.1 - 4.9e-26 91.4 0.3 9.1e-26 90.5 0.3 1.4 1 1 0 1 1 1 1 RhoGAP domain IIGP PF05049.13 CBY09288.1 - 0.0055 15.8 0.3 0.0066 15.5 0.3 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) CSN5_C PF18323.1 CBY09288.1 - 0.025 15.5 1.7 0.046 14.6 1.7 1.4 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF2408 PF10303.9 CBY09288.1 - 0.05 14.2 1.3 0.086 13.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1515 PF07439.11 CBY09288.1 - 0.11 12.6 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF5344 PF17279.2 CBY09288.1 - 0.12 13.0 4.1 0.23 12.1 4.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Raptor_N PF14538.6 CBY09288.1 - 0.17 11.8 0.7 1.6 8.7 0.6 2.0 1 1 1 2 2 2 0 Raptor N-terminal CASPase like domain DASH_Hsk3 PF08227.11 CBY09288.1 - 0.62 10.5 3.5 4.4 7.7 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like RRM_1 PF00076.22 CBY09289.1 - 1.6e-74 245.7 1.4 4.3e-19 68.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBY09289.1 - 5.4e-26 90.6 0.2 1.3e-25 89.3 0.2 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CBY09289.1 - 1.3e-08 34.5 0.1 0.0089 15.9 0.0 3.5 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBY09289.1 - 3.8e-06 26.8 0.2 0.022 14.8 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBY09289.1 - 0.0022 18.1 0.5 4.2 7.6 0.1 4.5 3 2 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 CBY09289.1 - 0.024 14.7 1.5 19 5.4 0.1 4.7 5 1 0 5 5 5 0 Limkain b1 YflT PF11181.8 CBY09289.1 - 0.025 15.1 1.1 3.9 8.1 0.3 3.1 3 0 0 3 3 3 0 Heat induced stress protein YflT SET_assoc PF11767.8 CBY09289.1 - 0.079 12.6 1.3 22 4.8 0.0 3.7 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated RNA_bind PF08675.11 CBY09289.1 - 0.18 11.9 0.2 4.3 7.4 0.0 3.2 4 0 0 4 4 4 0 RNA binding domain TPH PF13868.6 CBY09290.1 - 1.1e-54 185.2 111.8 1.4e-54 184.9 111.8 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain TPH PF13868.6 CBY09291.1 - 5.5e-14 51.4 7.2 5.5e-14 51.4 7.2 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RITA PF17066.5 CBY09291.1 - 0.00024 20.8 0.5 0.00024 20.8 0.5 1.8 1 1 1 2 2 2 1 RBPJ-interacting and tubulin associated protein DUF4522 PF15022.6 CBY09291.1 - 0.71 10.2 5.5 7.7 6.8 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4522) Ribosom_S12_S23 PF00164.25 CBY09292.1 - 3.4e-51 171.7 0.4 4.3e-51 171.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 NAP PF00956.18 CBY09293.1 - 1.9e-92 309.3 10.6 2.2e-92 309.1 10.6 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF4107 PF13389.6 CBY09293.1 - 0.066 13.4 0.2 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) AHSA1 PF08327.11 CBY09293.1 - 0.21 11.8 1.2 26 5.0 0.0 2.8 2 1 1 3 3 3 0 Activator of Hsp90 ATPase homolog 1-like protein Ribosomal_L35Ae PF01247.18 CBY09294.1 - 9.6e-44 147.5 0.9 1.1e-43 147.3 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CBY09294.1 - 0.0056 16.9 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain TPR_12 PF13424.6 CBY09295.1 - 9.3e-23 80.3 9.5 3.6e-07 30.4 0.0 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 CBY09295.1 - 1.3e-08 34.4 6.9 0.088 12.7 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY09295.1 - 2.8e-05 23.7 1.2 4.8e-05 22.9 1.2 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 CBY09295.1 - 0.0018 18.3 5.3 0.93 9.8 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY09295.1 - 0.042 13.7 0.3 1.9 8.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4107 PF13389.6 CBY09295.1 - 0.11 12.6 0.5 0.27 11.4 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) TPR_14 PF13428.6 CBY09295.1 - 0.17 12.8 0.5 77 4.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SurA_N PF09312.11 CBY09295.1 - 0.21 11.6 3.4 0.53 10.4 3.4 1.6 1 0 0 1 1 1 0 SurA N-terminal domain CLU PF13236.6 CBY09296.1 - 1.3e-77 260.5 0.0 3.1e-77 259.4 0.0 1.6 2 0 0 2 2 2 1 Clustered mitochondria CLU_N PF15044.6 CBY09296.1 - 4e-14 52.7 0.2 1.9e-12 47.4 0.0 3.0 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 CBY09296.1 - 0.0072 16.4 0.0 0.034 14.2 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) DUF2555 PF10742.9 CBY09296.1 - 0.097 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Flu_M2 PF00599.17 CBY09298.1 - 0.12 12.5 0.1 0.25 11.5 0.0 1.5 1 1 0 1 1 1 0 Influenza Matrix protein (M2) CdhD PF03599.16 CBY09298.1 - 0.17 10.5 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Nop10p PF04135.12 CBY09299.1 - 8.4e-24 83.4 0.1 9.8e-24 83.2 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Rhodanese PF00581.20 CBY09300.1 - 7.1e-11 42.6 0.1 2.1e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Abhydrolase_1 PF00561.20 CBY09301.1 - 3.8e-20 72.6 0.2 1.3e-13 51.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CBY09301.1 - 1.2e-19 69.6 0.1 2.5e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CBY09301.1 - 1.4e-10 40.8 0.1 1.8e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBY09301.1 - 0.00042 21.0 0.0 0.00075 20.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 CBY09301.1 - 0.0025 17.7 0.0 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 CBY09301.1 - 0.081 12.7 0.0 0.89 9.3 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family TPR_7 PF13176.6 CBY09302.1 - 0.00087 19.1 2.0 0.86 9.8 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY09302.1 - 0.0011 18.9 1.2 12 6.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY09302.1 - 0.01 16.1 1.2 5.6 7.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY09302.1 - 0.027 14.7 0.5 19 5.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY09302.1 - 0.037 13.9 0.1 1.6 8.7 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Mt_ATP-synt_D PF05873.12 CBY09302.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Calsarcin PF05556.11 CBY09306.1 - 0.043 13.3 8.2 0.028 14.0 3.0 2.1 1 1 1 2 2 2 0 Calcineurin-binding protein (Calsarcin) MDFI PF15316.6 CBY09306.1 - 7.1 6.7 9.6 3.1 7.8 1.7 2.2 1 1 1 2 2 2 0 MyoD family inhibitor Calsarcin PF05556.11 CBY09307.1 - 0.0052 16.4 1.9 0.0052 16.4 1.9 2.1 1 1 1 2 2 2 1 Calcineurin-binding protein (Calsarcin) RGS_DHEX PF18148.1 CBY09307.1 - 0.12 12.6 1.3 0.25 11.5 1.3 1.6 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain DNA_pol_B_2 PF03175.13 CBY09308.1 - 4.7e-09 35.6 5.4 8.9e-09 34.7 5.4 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral AF-4 PF05110.13 CBY09309.1 - 2 6.4 24.8 2 6.4 24.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ANAPC_CDC26 PF10471.9 CBY09309.1 - 2.2 9.2 9.3 2.6 8.9 9.3 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DHHW PF14286.6 CBY09309.1 - 3.4 6.9 9.1 3.4 6.9 9.1 1.0 1 0 0 1 1 1 0 DHHW protein RT_RNaseH_2 PF17919.1 CBY09312.1 - 4.1e-28 97.4 0.5 4.4e-28 97.2 0.5 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY09312.1 - 1.6e-20 73.3 0.1 2.1e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY09313.1 - 9.8e-14 51.2 0.7 9.8e-14 51.2 0.7 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain Ectoine_synth PF06339.12 CBY09314.1 - 0.053 13.7 0.1 0.059 13.6 0.1 1.2 1 1 0 1 1 1 0 Ectoine synthase Mcm10 PF09332.11 CBY09317.1 - 1.3 8.4 17.1 1.7 8.0 17.1 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Dimer_Tnp_hAT PF05699.14 CBY09319.1 - 1.1e-07 31.5 0.6 3.4e-07 30.0 0.4 2.0 1 1 1 2 2 2 1 hAT family C-terminal dimerisation region Cdc13_OB2 PF18691.1 CBY09320.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Cell division control protein 13, OB2 domain Phage_integrase PF00589.22 CBY09322.1 - 0.017 14.9 0.1 0.2 11.4 0.1 2.8 2 1 0 2 2 2 0 Phage integrase family Alpha-mann_mid PF09261.11 CBY09322.1 - 0.069 13.3 0.1 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 Alpha mannosidase middle domain Mt_ATP-synt_B PF05405.14 CBY09322.1 - 0.13 11.9 2.1 0.32 10.6 2.1 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ORMDL PF04061.14 CBY09323.1 - 0.11 12.2 0.2 0.43 10.4 0.1 1.8 2 0 0 2 2 2 0 ORMDL family Colicin_D PF11429.8 CBY09327.1 - 0.14 12.6 0.0 2.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Colicin D DUF3357 PF11837.8 CBY09328.1 - 0.054 14.0 0.1 0.095 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Dam PF05869.11 CBY09329.1 - 0.0018 17.9 0.0 0.0052 16.4 0.0 1.7 2 0 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) eIF3_N PF09440.10 CBY09330.1 - 2.4 8.6 9.4 4.2 7.8 2.4 2.3 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain API5 PF05918.11 CBY09331.1 - 0.014 14.3 8.1 0.029 13.2 6.9 2.0 1 1 1 2 2 2 0 Apoptosis inhibitory protein 5 (API5) PIN_10 PF18478.1 CBY09331.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 PIN like domain BTV_NS2 PF04514.12 CBY09331.1 - 0.27 10.0 4.8 0.4 9.5 4.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Seryl_tRNA_N PF02403.22 CBY09331.1 - 0.82 9.9 12.9 0.19 12.0 7.0 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_18 PF13512.6 CBY09333.1 - 0.034 14.3 0.1 0.11 12.7 0.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF445 PF04286.12 CBY09333.1 - 0.13 12.1 7.8 0.013 15.3 3.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) RED_C PF07807.11 CBY09333.1 - 4.2 7.9 16.3 0.48 10.9 2.3 3.8 3 1 1 4 4 4 0 RED-like protein C-terminal region Ig_3 PF13927.6 CBY09340.1 - 0.0025 18.4 3.2 0.11 13.1 0.2 3.6 4 1 0 4 4 4 1 Immunoglobulin domain EphA2_TM PF14575.6 CBY09340.1 - 0.061 14.2 0.0 0.14 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4330 PF14221.6 CBY09340.1 - 0.094 12.9 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) DUF2500 PF10694.9 CBY09340.1 - 0.098 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Stevor PF17410.2 CBY09340.1 - 0.12 11.9 0.2 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame MLANA PF14991.6 CBY09340.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A V-set PF07686.17 CBY09340.1 - 0.26 11.5 1.3 1 9.6 0.2 2.5 2 1 0 2 2 2 0 Immunoglobulin V-set domain Phospholip_A2_1 PF00068.19 CBY09341.1 - 3e-09 37.3 11.3 3e-09 37.3 11.3 2.0 2 0 0 2 2 2 1 Phospholipase A2 DUF1547 PF07577.11 CBY09341.1 - 0.01 16.2 0.0 0.03 14.7 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) RT_RNaseH_2 PF17919.1 CBY09343.1 - 9.3e-29 99.4 0.0 2.6e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY09343.1 - 3.7e-22 78.6 0.0 7.7e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY09343.1 - 4.9e-17 62.2 0.1 1e-16 61.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 CBY09343.1 - 0.062 12.7 0.0 0.18 11.2 0.0 1.8 1 1 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phospholip_A2_1 PF00068.19 CBY09344.1 - 2e-10 41.1 11.1 2e-10 41.1 11.1 2.3 2 0 0 2 2 2 1 Phospholipase A2 PriCT_1 PF08708.11 CBY09344.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) LRR_4 PF12799.7 CBY09345.1 - 0.00038 20.8 0.1 0.16 12.5 0.0 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) CBM46 PF18448.1 CBY09346.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain Chromo PF00385.24 CBY09347.1 - 5.8e-32 109.4 9.7 2.4e-12 46.6 0.0 4.3 4 0 0 4 4 4 4 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CBY09347.1 - 0.022 14.9 0.2 7.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Chromo shadow domain PWWP PF00855.17 CBY09347.1 - 0.047 14.1 6.3 0.11 12.9 0.7 3.1 1 1 3 4 4 4 0 PWWP domain Tudor-knot PF11717.8 CBY09347.1 - 0.049 13.5 0.1 0.049 13.5 0.1 3.4 2 2 2 4 4 4 0 RNA binding activity-knot of a chromodomain Sld5 PF05916.11 CBY09348.1 - 3.5e-15 56.4 0.5 6.2e-15 55.6 0.5 1.4 1 0 0 1 1 1 1 GINS complex protein OST-HTH PF12872.7 CBY09348.1 - 0.0042 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 OST-HTH/LOTUS domain ANAPC4 PF12896.7 CBY09351.1 - 8.5e-07 28.7 3.4 2.4e-06 27.2 3.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF3105 PF11303.8 CBY09352.1 - 5.4e-21 75.1 0.1 1.1e-20 74.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) DUF3258 PF11646.8 CBY09352.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF3258 DUF5394 PF17372.2 CBY09352.1 - 0.11 12.0 0.8 0.17 11.4 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5394) zf-H2C2_2 PF13465.6 CBY09355.1 - 0.00087 19.6 27.5 0.042 14.3 1.3 6.3 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY09355.1 - 0.0045 17.7 31.1 0.011 16.5 0.8 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY09355.1 - 0.015 15.7 35.1 0.026 15.0 0.8 5.7 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY09355.1 - 0.09 13.1 13.6 2 8.8 0.1 4.2 3 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.6 CBY09355.1 - 0.22 11.6 9.9 2 8.6 0.9 3.2 3 1 0 3 3 3 0 Zinc-finger zf-H2C2_5 PF13909.6 CBY09355.1 - 0.36 10.6 0.0 0.36 10.6 0.0 5.2 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CBY09355.1 - 0.73 9.7 13.0 0.63 9.8 0.1 3.5 4 0 0 4 4 4 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 CBY09355.1 - 0.87 10.4 7.7 1.4 9.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon family HalOD2 PF18547.1 CBY09355.1 - 4 7.4 7.6 11 6.0 1.7 2.9 2 1 0 2 2 2 0 Halobacterial output domain 2 zinc_ribbon_16 PF17034.5 CBY09356.1 - 0.48 10.6 13.3 6.1 7.1 12.9 2.8 2 1 0 2 2 2 0 Zinc-ribbon like family Macoilin PF09726.9 CBY09358.1 - 1.5e-06 27.1 72.5 5.2e-05 22.0 72.5 3.0 1 1 0 1 1 1 1 Macoilin family MCC-bdg_PDZ PF10506.9 CBY09358.1 - 2.1 8.4 16.7 4.2 7.5 6.5 3.9 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome 2-oxoacid_dh PF00198.23 CBY09359.1 - 2.9e-64 216.7 0.0 3.5e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Ntox10 PF15520.6 CBY09359.1 - 0.01 15.7 0.9 0.013 15.4 0.2 1.6 2 0 0 2 2 2 0 Novel toxin 10 DUF5536 PF17688.1 CBY09359.1 - 0.051 13.5 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5536) DUF2703 PF10865.8 CBY09359.1 - 0.22 11.7 0.2 1.2 9.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) NUC173 PF08161.12 CBY09361.1 - 0.023 14.3 0.5 0.13 12.0 0.1 2.3 2 1 0 2 2 2 0 NUC173 domain Ribosomal_L27A PF00828.19 CBY09363.1 - 5.1e-24 85.4 0.0 7.7e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DEAD PF00270.29 CBY09364.1 - 2.3e-15 56.8 0.0 2e-14 53.8 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY09364.1 - 1.6e-14 54.2 0.0 3.9e-13 49.7 0.0 2.7 1 1 1 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 CBY09364.1 - 7.7e-09 35.3 0.0 2.4e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 CBY09364.1 - 1.3e-06 29.0 3.2 1.9e-06 28.5 0.4 2.9 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 CBY09364.1 - 0.066 13.2 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 HRDC domain HTH_Tnp_Tc5 PF03221.16 CBY09364.1 - 0.28 11.2 1.9 6.1 6.9 0.1 3.0 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain HUN PF08729.10 CBY09364.1 - 0.35 10.9 5.0 1.7 8.7 5.0 2.3 1 0 0 1 1 1 0 HPC2 and ubinuclein domain ApoLp-III PF07464.11 CBY09366.1 - 7.8e-05 22.8 7.1 0.00086 19.4 7.1 2.2 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 CBY09366.1 - 0.00053 19.9 1.9 0.00071 19.5 1.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2935 PF11155.8 CBY09366.1 - 0.0026 18.1 0.7 0.034 14.5 0.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 CBY09366.1 - 0.0045 17.0 0.8 0.0078 16.3 0.8 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF87 PF01935.17 CBY09366.1 - 0.0074 16.4 2.0 0.0085 16.2 2.0 1.1 1 0 0 1 1 1 1 Helicase HerA, central domain Actin_micro PF17003.5 CBY09366.1 - 0.0089 15.3 1.3 0.01 15.1 1.3 1.1 1 0 0 1 1 1 1 Putative actin-like family HIP1_clath_bdg PF16515.5 CBY09366.1 - 0.009 16.6 3.6 0.018 15.7 3.6 1.5 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 KIP1 PF07765.12 CBY09366.1 - 0.017 15.2 2.7 0.029 14.5 2.0 1.7 2 0 0 2 2 1 0 KIP1-like protein Phasin PF05597.11 CBY09366.1 - 0.031 14.3 2.6 0.11 12.5 2.6 1.9 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1539 PF07560.11 CBY09366.1 - 0.04 14.0 1.4 0.069 13.2 1.3 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) BshC PF10079.9 CBY09366.1 - 0.04 12.7 3.2 0.051 12.3 3.2 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Prominin PF05478.11 CBY09366.1 - 0.058 11.3 2.9 0.065 11.2 2.9 1.0 1 0 0 1 1 1 0 Prominin DUF883 PF05957.13 CBY09366.1 - 0.062 13.9 1.9 0.5 11.0 0.2 2.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) PLAC9 PF15205.6 CBY09366.1 - 0.088 13.2 1.1 4.9 7.6 0.0 2.3 1 1 1 2 2 2 0 Placenta-specific protein 9 DUF16 PF01519.16 CBY09366.1 - 0.1 13.1 2.8 0.33 11.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 HSCB_C PF07743.13 CBY09366.1 - 0.13 12.8 5.4 3.8 8.1 5.4 2.3 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain RecG_N PF17190.4 CBY09366.1 - 0.13 13.0 3.9 9.1 7.1 2.4 2.4 1 1 1 2 2 2 0 RecG N-terminal helical domain RsbU_N PF08673.10 CBY09366.1 - 0.13 12.3 0.5 0.24 11.5 0.5 1.4 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF948 PF06103.11 CBY09366.1 - 0.16 12.2 1.8 0.32 11.3 1.3 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DASH_Duo1 PF08651.10 CBY09366.1 - 0.19 11.5 3.1 1.7 8.5 0.2 2.8 1 1 2 3 3 3 0 DASH complex subunit Duo1 YtxH PF12732.7 CBY09366.1 - 0.4 11.3 2.9 2.6 8.7 2.9 2.3 1 1 0 1 1 1 0 YtxH-like protein DUF4404 PF14357.6 CBY09366.1 - 0.78 10.4 6.8 0.56 10.9 1.0 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4404) GATA PF00320.27 CBY09367.1 - 2.7e-25 87.7 21.4 9.2e-13 47.6 7.6 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CBY09367.1 - 4e-07 29.4 7.2 0.00075 19.0 1.6 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Elf1 PF05129.13 CBY09367.1 - 0.14 12.2 8.5 0.8 9.8 1.6 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.10 CBY09367.1 - 0.6 9.9 6.5 0.32 10.8 0.4 2.9 3 0 0 3 3 3 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 CBY09367.1 - 0.71 10.0 5.6 4.3 7.5 0.2 2.9 2 1 1 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 CBY09367.1 - 1.4 8.8 7.8 3.8 7.4 2.3 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 CBY09367.1 - 1.7 8.8 9.8 1.9 8.7 0.5 2.6 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Prim_Zn_Ribbon PF08273.12 CBY09367.1 - 2.1 8.7 4.5 33 4.9 1.0 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase E1-E2_ATPase PF00122.20 CBY09368.1 - 0.0008 19.0 0.2 0.001 18.6 0.2 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CBY09369.1 - 7.2e-17 62.4 0.3 4.3e-16 59.8 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 CBY09369.1 - 4e-12 46.2 0.0 5.7e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 CBY09369.1 - 2.4e-07 30.7 2.7 0.00015 21.6 1.1 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY09369.1 - 0.0019 18.6 0.1 0.0033 17.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase OHCU_decarbox PF09349.10 CBY09369.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 OHCU decarboxylase TFIIE_beta PF02186.15 CBY09369.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 TFIIE beta subunit core domain Cation_ATPase_C PF00689.21 CBY09370.1 - 3e-19 69.5 0.1 3.3e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF1290 PF06947.12 CBY09370.1 - 0.0058 16.7 0.1 0.0086 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1290) Pkinase PF00069.25 CBY09371.1 - 2.9e-08 33.4 0.6 2.9e-08 33.4 0.6 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09371.1 - 0.0086 15.4 1.0 0.025 13.9 0.2 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase nlz1 PF12402.8 CBY09373.1 - 0.029 14.8 0.0 0.1 13.1 0.0 1.7 2 0 0 2 2 2 0 NocA-like zinc-finger protein 1 zf-C3HC4_4 PF15227.6 CBY09374.1 - 9.8e-05 22.4 16.2 0.00017 21.7 16.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBY09374.1 - 0.00012 21.9 12.9 0.0002 21.2 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY09374.1 - 0.00066 19.5 16.7 0.0014 18.4 16.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY09374.1 - 0.011 15.7 13.7 0.021 14.8 13.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 CBY09374.1 - 0.019 15.3 15.0 0.044 14.1 15.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 CBY09374.1 - 0.045 13.7 15.8 0.099 12.6 15.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 CBY09374.1 - 0.29 11.0 11.6 0.78 9.7 11.6 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY09374.1 - 1.8 8.5 15.3 3.9 7.4 15.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY09374.1 - 1.9 8.4 17.3 9.1 6.2 17.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SANTA PF09133.10 CBY09375.1 - 1.3e-05 25.6 0.1 2.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 SANTA (SANT Associated) EF-hand_1 PF00036.32 CBY09377.1 - 1.5e-20 71.1 17.2 0.0011 18.4 0.0 6.8 7 0 0 7 7 7 6 EF hand EF-hand_7 PF13499.6 CBY09377.1 - 3.9e-19 68.9 21.7 5.9e-08 33.0 0.9 4.4 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBY09377.1 - 2e-15 55.3 17.0 0.037 14.0 0.0 6.7 7 0 0 7 7 7 6 EF-hand domain EF-hand_5 PF13202.6 CBY09377.1 - 4.1e-12 45.0 20.6 0.0038 16.7 0.1 6.4 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 CBY09377.1 - 1.3e-11 44.2 9.5 0.14 12.1 0.1 5.6 4 1 1 5 5 5 5 EF-hand domain pair EFhand_Ca_insen PF08726.10 CBY09377.1 - 0.022 14.8 1.2 0.38 10.9 0.0 2.7 2 1 1 3 3 3 0 Ca2+ insensitive EF hand EF-hand_10 PF14788.6 CBY09377.1 - 0.5 10.3 6.2 32 4.5 0.1 4.2 5 0 0 5 5 5 0 EF hand TPR_19 PF14559.6 CBY09378.1 - 0.0021 18.5 0.5 0.077 13.5 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY09378.1 - 0.0069 17.1 0.2 63 4.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY09378.1 - 1.1 9.6 10.2 36 4.8 0.2 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Cg6151-P PF10233.9 CBY09379.1 - 1.7e-14 54.1 11.7 2e-14 53.9 11.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 CBY09379.1 - 0.0014 18.4 1.9 0.0018 18.0 1.9 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 PRA1 PF03208.19 CBY09379.1 - 0.96 9.1 5.4 1.3 8.6 5.4 1.2 1 0 0 1 1 1 0 PRA1 family protein COPI_assoc PF08507.10 CBY09379.1 - 2 8.5 11.8 2.8 8.0 11.8 1.4 1 1 0 1 1 1 0 COPI associated protein SseC PF04888.12 CBY09379.1 - 4.2 6.9 11.8 0.61 9.6 1.6 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF2628 PF10947.8 CBY09379.1 - 9.3 6.7 6.7 1.7 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) S-AdoMet_synt_C PF02773.16 CBY09381.1 - 4.5e-68 227.5 0.1 7.6e-68 226.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CBY09381.1 - 5.5e-43 146.0 0.0 1.1e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CBY09381.1 - 5.7e-42 142.4 0.7 2.1e-41 140.6 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CBY09381.1 - 0.056 12.2 0.4 0.15 10.8 0.2 1.7 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) RNase_H PF00075.24 CBY09382.1 - 0.0043 17.2 0.0 0.0051 17.0 0.0 1.1 1 0 0 1 1 1 1 RNase H Trypsin PF00089.26 CBY09383.1 - 1.1e-50 172.5 0.1 1.1e-50 172.5 0.1 2.4 2 0 0 2 2 2 1 Trypsin Mucin PF01456.17 CBY09383.1 - 1.1e-09 38.4 28.9 1.1e-09 38.4 28.9 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein TSP_1 PF00090.19 CBY09383.1 - 1.7e-08 34.6 32.8 3.8e-06 27.0 8.1 7.5 8 0 0 8 8 8 2 Thrombospondin type 1 domain Trypsin_2 PF13365.6 CBY09383.1 - 2.2e-07 31.9 0.0 6.2e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF5526 PF17664.1 CBY09384.1 - 9.6e-13 48.0 9.5 1.2e-12 47.8 9.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5526) Hydrolase_4 PF12146.8 CBY09386.1 - 7.7e-09 35.2 0.0 0.00044 19.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY09386.1 - 1.3e-06 28.2 0.0 0.041 13.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY09386.1 - 2.3e-05 25.1 0.0 0.00089 19.9 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBY09386.1 - 5.8e-05 22.7 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF818 PF05677.12 CBY09386.1 - 0.00018 20.6 0.1 0.00029 19.9 0.1 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Asp2 PF16929.5 CBY09386.1 - 0.0013 17.8 0.0 0.0093 15.0 0.0 1.9 2 0 0 2 2 2 1 Accessory Sec system GspB-transporter DLH PF01738.18 CBY09386.1 - 0.0087 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF1057 PF06342.12 CBY09386.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 CBY09386.1 - 0.025 14.4 0.0 0.12 12.1 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 CBY09386.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 CBY09386.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Cep57_CLD_2 PF14197.6 CBY09387.1 - 0.01 15.9 0.7 0.035 14.2 0.2 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CPSF_A PF03178.15 CBY09388.1 - 1.8e-73 247.6 0.0 4.5e-72 243.1 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.9 CBY09388.1 - 9.9e-38 130.0 0.1 1.3e-37 129.6 0.1 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Peptidase_S49_N PF08496.10 CBY09388.1 - 2.1 8.4 6.0 0.39 10.8 1.7 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Pkinase PF00069.25 CBY09389.1 - 1e-31 110.3 0.0 1.5e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09389.1 - 1.5e-20 73.6 0.0 1.9e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY09389.1 - 0.00096 19.1 1.9 6 6.7 0.0 4.0 2 2 2 4 4 4 2 Phosphotransferase enzyme family DUF4210 PF13915.6 CBY09390.1 - 5.2e-15 55.8 0.1 1.1e-12 48.3 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 CBY09390.1 - 2.9e-14 53.0 0.1 6.6e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4733 PF15878.5 CBY09390.1 - 0.095 13.2 0.0 0.76 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4733) Ank_2 PF12796.7 CBY09391.1 - 9.8e-19 67.7 0.0 9.5e-15 55.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY09391.1 - 2.2e-15 56.5 0.1 2.9e-05 24.3 0.0 4.0 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY09391.1 - 3e-14 53.2 0.2 6.5e-08 33.0 0.0 3.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY09391.1 - 2.6e-11 42.7 0.0 0.00067 19.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CBY09391.1 - 1.2e-10 41.3 0.0 0.0036 17.7 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat PTS_IIA PF02255.16 CBY09391.1 - 0.031 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit PKD_channel PF08016.12 CBY09393.1 - 0.019 13.7 0.1 0.028 13.1 0.1 1.2 1 0 0 1 1 1 0 Polycystin cation channel zf-C4 PF00105.18 CBY09395.1 - 9.9e-28 96.4 15.8 2e-27 95.4 15.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) TIG PF01833.24 CBY09396.1 - 9.6e-17 60.8 3.2 0.00015 21.8 0.0 5.0 5 0 0 5 5 5 4 IPT/TIG domain PA14 PF07691.12 CBY09396.1 - 4.6e-06 26.5 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Ank_2 PF12796.7 CBY09396.1 - 6.3e-05 23.5 0.2 0.00015 22.3 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) GLEYA PF10528.9 CBY09396.1 - 0.0067 16.8 0.0 0.03 14.8 0.0 2.1 2 0 0 2 2 2 1 GLEYA domain zf-C4 PF00105.18 CBY09397.1 - 3.7e-27 94.6 15.8 7.8e-27 93.5 15.8 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) TIG PF01833.24 CBY09398.1 - 4.3e-97 318.3 49.3 9.2e-13 48.1 0.7 16.5 15 2 1 16 16 16 14 IPT/TIG domain G8 PF10162.9 CBY09398.1 - 9.9e-48 161.3 0.1 3.6e-28 98.1 0.0 3.5 3 0 0 3 3 3 2 G8 domain Beta_helix PF13229.6 CBY09398.1 - 2.6e-05 24.1 23.1 0.0006 19.7 4.3 5.2 4 0 0 4 4 4 2 Right handed beta helix region PA14 PF07691.12 CBY09398.1 - 3.7e-05 23.6 0.0 9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 CBY09398.1 - 0.032 14.7 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 GLEYA domain LRR_8 PF13855.6 CBY09399.1 - 9.6e-05 22.1 0.8 9.6e-05 22.1 0.8 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY09399.1 - 0.01 16.2 7.6 0.021 15.2 6.6 2.1 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) CIA30 PF08547.12 CBY09400.1 - 9.8e-17 61.4 0.0 1.1e-16 61.3 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 CBY09400.1 - 0.0039 17.1 0.1 0.0043 17.0 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) Pkinase PF00069.25 CBY09401.1 - 6.1e-48 163.5 0.0 8.4e-47 159.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09401.1 - 2.4e-26 92.6 0.0 1.8e-23 83.1 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY09401.1 - 1.8e-06 27.5 0.0 3.3e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY09401.1 - 2.7e-06 26.5 0.0 4.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CBY09401.1 - 0.003 17.2 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBY09401.1 - 0.0033 17.4 0.1 0.18 11.7 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Peptidase_S8 PF00082.22 CBY09403.1 - 6.2e-40 137.3 8.1 7.9e-40 137.0 8.1 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY09403.1 - 2.3e-27 94.9 0.1 3.8e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain VSP PF03302.13 CBY09403.1 - 3e-05 23.1 53.2 4.1e-05 22.6 10.7 3.3 1 1 2 3 3 3 3 Giardia variant-specific surface protein Furin-like_2 PF15913.5 CBY09403.1 - 0.0077 16.4 51.9 0.058 13.6 23.6 2.7 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich Furin-like PF00757.20 CBY09403.1 - 1.5 8.7 72.4 0.12 12.2 43.7 3.8 1 1 2 3 3 3 0 Furin-like cysteine rich region Cadherin PF00028.17 CBY09405.1 - 5e-16 58.9 0.0 5.2e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Cadherin domain Cadherin_2 PF08266.12 CBY09405.1 - 0.069 13.0 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Cadherin-like DUF5089 PF17002.5 CBY09406.1 - 6.1e-08 32.8 16.2 7.5e-08 32.5 16.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) SNAP-25 PF00835.19 CBY09406.1 - 1.3e-06 28.6 2.2 4.1e-06 27.0 2.2 1.8 1 0 0 1 1 1 1 SNAP-25 family SNARE PF05739.19 CBY09406.1 - 0.00026 20.9 5.0 0.081 12.9 0.4 2.6 2 0 0 2 2 2 2 SNARE domain Snapin_Pallidin PF14712.6 CBY09406.1 - 0.0005 20.4 6.6 0.01 16.2 1.0 2.4 2 0 0 2 2 2 2 Snapin/Pallidin V-SNARE_C PF12352.8 CBY09406.1 - 0.0052 17.0 2.0 0.0052 17.0 2.0 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF4446 PF14584.6 CBY09406.1 - 0.009 16.0 7.7 0.043 13.8 0.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF4446) T3SSipB PF16535.5 CBY09406.1 - 0.019 15.4 3.6 0.58 10.6 0.7 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB MMPL PF03176.15 CBY09406.1 - 0.044 12.7 1.2 0.082 11.8 1.1 1.6 1 1 0 1 1 1 0 MMPL family Rx_N PF18052.1 CBY09406.1 - 0.083 13.2 1.0 0.34 11.2 0.1 2.1 2 0 0 2 2 2 0 Rx N-terminal domain DUF2096 PF09869.9 CBY09406.1 - 0.12 12.5 4.4 0.18 11.9 0.4 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Tho2 PF11262.8 CBY09406.1 - 0.15 11.2 0.1 0.15 11.2 0.1 2.3 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 P4Ha_N PF08336.11 CBY09406.1 - 0.34 10.9 5.0 0.13 12.2 0.6 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF948 PF06103.11 CBY09406.1 - 0.44 10.8 7.8 0.6 10.4 1.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 CBY09406.1 - 0.47 10.7 11.7 0.88 9.8 1.9 3.0 3 1 0 3 3 3 0 Haemolysin XhlA FlaC_arch PF05377.11 CBY09406.1 - 0.61 10.5 11.8 1.3 9.5 2.0 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 CBY09406.1 - 1 9.4 7.8 0.82 9.7 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 CBY09406.1 - 1.1 9.3 7.2 8.2 6.5 0.9 2.4 2 0 0 2 2 2 0 Laminin Domain II MscS_porin PF12795.7 CBY09406.1 - 1.7 8.1 11.4 4.2 6.9 1.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF16 PF01519.16 CBY09406.1 - 2.2 8.8 11.0 2.3 8.7 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 Sec20 PF03908.13 CBY09406.1 - 2.2 8.3 5.2 0.98 9.4 1.1 2.1 2 0 0 2 2 2 0 Sec20 CH_2 PF06294.11 CBY09407.1 - 8.8e-05 22.6 0.0 0.00022 21.3 0.0 1.7 2 0 0 2 2 2 1 CH-like domain in sperm protein PP2C PF00481.21 CBY09409.1 - 6.6e-62 209.5 0.7 8.1e-62 209.2 0.1 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY09409.1 - 1.8e-05 24.5 0.7 0.00016 21.4 0.4 2.6 1 1 1 2 2 2 2 Protein phosphatase 2C RHH_8 PF17723.1 CBY09409.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family Mei5 PF10376.9 CBY09409.1 - 1.7 8.5 7.9 2.5 7.9 7.9 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein SMP_LBD PF17047.5 CBY09410.1 - 9e-36 123.0 0.2 2.1e-35 121.8 0.1 1.7 2 0 0 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 CBY09410.1 - 1.8e-18 66.7 0.3 3.5e-17 62.6 0.1 2.9 3 0 0 3 3 3 1 C2 domain UbiA PF01040.18 CBY09410.1 - 0.32 10.3 3.0 0.53 9.5 3.0 1.3 1 0 0 1 1 1 0 UbiA prenyltransferase family Methyltr_RsmB-F PF01189.17 CBY09411.1 - 9.5e-34 116.8 0.0 1.9e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F CTD_bind PF04818.13 CBY09411.1 - 6.7e-07 30.0 0.1 2.8e-06 28.0 0.1 2.2 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 CBY09411.1 - 0.0058 16.4 0.0 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spore_YhcN_YlaJ PF09580.10 CBY09411.1 - 0.012 15.7 2.0 0.065 13.3 2.0 2.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PHM7_cyt PF14703.6 CBY09411.1 - 0.066 13.4 0.1 0.27 11.5 0.1 2.1 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1741 PF08427.10 CBY09413.1 - 6.4e-52 176.5 4.1 1.4e-51 175.4 3.5 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) DUF382 PF04037.13 CBY09413.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF382) Sulfotransfer_1 PF00685.27 CBY09415.1 - 9.7e-19 67.9 2.2 2.6e-18 66.4 2.2 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY09415.1 - 0.00041 20.8 0.2 0.045 14.1 0.0 2.5 2 1 0 2 2 2 2 Sulfotransferase family Thioredoxin PF00085.20 CBY09416.1 - 2.1e-15 56.6 0.1 4.1e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CBY09416.1 - 3.8e-09 36.7 10.5 2e-05 24.6 5.6 2.6 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY09416.1 - 0.00086 19.7 1.7 0.0065 16.9 0.1 2.8 2 1 1 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 CBY09416.1 - 0.001 18.9 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 CBY09416.1 - 0.007 16.7 0.6 0.07 13.5 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like Pkinase PF00069.25 CBY09417.1 - 5e-59 199.8 0.0 8e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09417.1 - 4.3e-31 108.1 0.0 8.1e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY09417.1 - 1.6e-08 34.2 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY09417.1 - 0.0076 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0565 PF10561.9 CBY09417.1 - 1.8 7.7 7.5 3.3 6.8 7.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 LMBR1 PF04791.16 CBY09417.1 - 3.5 6.4 7.3 6.1 5.6 7.3 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein RNase_T PF00929.24 CBY09418.1 - 7.3e-23 81.9 0.0 1.6e-22 80.8 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DNA_methylase PF00145.17 CBY09418.1 - 0.048 13.0 1.0 0.79 9.0 0.0 2.2 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase WH1 PF00568.23 CBY09418.1 - 0.085 12.8 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 WH1 domain DREV PF05219.12 CBY09419.1 - 1.8e-19 69.9 0.1 1.5e-18 66.8 0.1 2.0 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_23 PF13489.6 CBY09419.1 - 5.2e-09 36.2 0.1 4.7e-07 29.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY09419.1 - 7.3e-07 29.9 0.1 1.6e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY09419.1 - 3.6e-05 23.6 0.0 5.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CBY09419.1 - 7.2e-05 22.5 0.4 0.00016 21.4 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 CBY09419.1 - 7.2e-05 23.4 0.0 0.00013 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY09419.1 - 0.00036 21.1 0.0 0.00065 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY09419.1 - 0.012 15.1 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 CBY09419.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Myosin_head PF00063.21 CBY09420.1 - 3.8e-222 739.3 3.0 6.5e-222 738.5 3.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CBY09420.1 - 2.9e-37 128.2 0.5 8.5e-37 126.6 0.7 1.6 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding AAA_22 PF13401.6 CBY09420.1 - 0.0054 17.0 0.0 0.39 11.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY09420.1 - 0.047 14.1 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 CBY09420.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PP1_inhibitor PF05361.12 CBY09420.1 - 0.095 12.7 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor ABC_tran PF00005.27 CBY09420.1 - 0.13 12.8 0.8 1.5 9.3 0.1 2.8 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CBY09420.1 - 8.8 6.8 9.5 0.72 10.3 1.0 3.1 3 1 0 3 3 3 0 AAA domain SH3_9 PF14604.6 CBY09421.1 - 8.7e-14 51.1 0.1 1.1e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY09421.1 - 1.3e-13 50.4 0.1 1.6e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY09421.1 - 2.4e-11 43.1 0.0 3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain Gpi1 PF05024.15 CBY09422.1 - 2.9e-50 170.9 9.2 2.9e-50 170.9 9.2 1.5 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) SOCS_box PF07525.16 CBY09422.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.2 2 1 0 2 2 2 0 SOCS box zf-C2H2_jaz PF12171.8 CBY09423.1 - 0.00076 19.7 1.8 0.0044 17.3 0.9 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-CW PF07496.15 CBY09423.1 - 0.065 13.3 2.2 5.7 7.0 0.0 2.8 2 0 0 2 2 2 0 CW-type Zinc Finger zf-C2H2_4 PF13894.6 CBY09423.1 - 0.15 13.0 0.3 0.15 13.0 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger AT_hook PF02178.19 CBY09423.1 - 0.21 11.6 5.9 0.35 10.9 3.0 2.7 2 0 0 2 2 2 0 AT hook motif IQ PF00612.27 CBY09424.1 - 0.00056 19.5 5.3 0.00099 18.7 0.4 3.1 2 1 1 3 3 3 1 IQ calmodulin-binding motif Borrelia_P83 PF05262.11 CBY09424.1 - 0.021 13.4 16.1 0.025 13.1 16.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein LRR_8 PF13855.6 CBY09425.1 - 1.9e-09 37.2 21.5 0.00074 19.2 5.2 4.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBY09425.1 - 5.2e-08 33.1 28.0 0.00023 21.5 2.1 5.3 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) EMP24_GP25L PF01105.24 CBY09426.1 - 1.7e-45 155.2 4.5 2e-45 155.0 4.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Methyltransf_3 PF01596.17 CBY09426.1 - 0.0077 15.4 0.1 0.017 14.3 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Innexin PF00876.18 CBY09426.1 - 0.008 15.5 0.3 0.012 14.9 0.3 1.3 1 0 0 1 1 1 1 Innexin CEP63 PF17045.5 CBY09427.1 - 0.0047 16.9 8.8 0.009 15.9 8.8 1.5 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Med9 PF07544.13 CBY09427.1 - 0.019 15.0 0.5 0.019 15.0 0.5 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2408 PF10303.9 CBY09427.1 - 0.053 14.1 9.2 1.3 9.6 9.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Wtap PF17098.5 CBY09427.1 - 0.18 11.7 8.6 1.1 9.2 2.6 2.5 1 1 1 2 2 2 0 WTAP/Mum2p family TPR_MLP1_2 PF07926.12 CBY09427.1 - 0.21 11.6 12.2 0.89 9.6 1.2 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Mito_carr PF00153.27 CBY09428.1 - 4.8e-60 199.5 2.2 4.8e-23 80.9 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein MBOAT_2 PF13813.6 CBY09428.1 - 0.12 12.7 0.3 0.35 11.2 0.0 2.0 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family LRR_9 PF14580.6 CBY09429.1 - 5.3e-10 39.1 2.2 1.5e-09 37.6 2.2 1.8 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBY09429.1 - 4.3e-05 23.8 3.9 4.3e-05 23.8 3.9 3.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY09429.1 - 0.016 15.0 7.6 0.016 15.0 7.6 2.5 1 1 2 3 3 3 0 Leucine rich repeat Amidinotransf PF02274.17 CBY09429.1 - 0.12 11.4 7.4 0.23 10.5 7.4 1.4 1 0 0 1 1 1 0 Amidinotransferase SbcD_C PF12320.8 CBY09429.1 - 0.31 11.3 4.8 0.27 11.5 2.0 2.5 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain HALZ PF02183.18 CBY09429.1 - 0.37 11.0 12.5 0.059 13.6 1.9 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 CBY09429.1 - 1.2 9.0 8.0 0.92 9.3 0.8 3.0 2 0 0 2 2 2 0 Septum formation initiator FAM195 PF14799.6 CBY09429.1 - 1.3 9.4 6.1 0.36 11.2 1.6 2.3 2 0 0 2 2 2 0 FAM195 family LRR_6 PF13516.6 CBY09429.1 - 1.6 9.0 8.9 7.7 6.8 0.3 3.5 2 1 1 3 3 3 0 Leucine Rich repeat RRM_1 PF00076.22 CBY09430.1 - 1.5e-21 76.0 0.0 6.7e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CBY09430.1 - 0.0001 22.2 0.6 0.021 14.8 0.1 2.5 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_occluded PF16842.5 CBY09430.1 - 0.00015 21.5 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Ribosomal_L20 PF00453.18 CBY09432.1 - 0.00074 19.6 0.1 0.0012 18.9 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L20 TPT PF03151.16 CBY09433.1 - 2.8e-15 56.4 15.2 3.2e-15 56.3 15.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY09433.1 - 1.9e-07 31.4 29.3 0.00024 21.3 10.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family GCP_C_terminal PF04130.13 CBY09434.1 - 2e-67 227.8 10.0 3.3e-67 227.1 10.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBY09434.1 - 7.5e-55 186.7 1.2 1.2e-54 186.0 1.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal PHO4 PF01384.20 CBY09435.1 - 8.6e-111 370.2 19.4 1.1e-110 369.9 19.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family YscK PF06578.12 CBY09435.1 - 0.085 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Cyt-b5 PF00173.28 CBY09436.1 - 6.8e-12 45.4 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ubiquitin PF00240.23 CBY09436.1 - 0.00063 19.4 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY09436.1 - 0.0052 16.6 0.1 0.0092 15.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Mac-1 PF09028.10 CBY09436.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Mac 1 AAA_23 PF13476.6 CBY09437.1 - 4.2e-16 60.0 15.1 4.2e-16 60.0 15.1 5.2 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.19 CBY09437.1 - 6.8e-13 48.6 0.3 6.8e-13 48.6 0.3 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CBY09437.1 - 2.3e-09 37.5 30.0 2.3e-09 37.5 30.0 4.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CBY09437.1 - 1.5e-05 24.6 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CBY09437.1 - 0.002 18.0 0.2 0.002 18.0 0.2 3.8 4 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CBY09437.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.4 3 0 0 3 3 3 0 RsgA GTPase AAA_27 PF13514.6 CBY09437.1 - 0.14 11.7 0.0 0.14 11.7 0.0 4.0 3 2 2 5 5 5 0 AAA domain AAA_22 PF13401.6 CBY09437.1 - 0.16 12.2 2.5 0.42 10.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 CBY09437.1 - 0.25 11.3 2.3 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MukB PF04310.12 CBY09437.1 - 0.28 10.9 2.3 0.52 10.1 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal Sec1 PF00995.23 CBY09438.1 - 3.6e-06 26.5 1.2 8.7e-06 25.2 0.1 2.0 2 1 0 2 2 2 1 Sec1 family DUF2281 PF10047.9 CBY09438.1 - 0.075 13.7 0.0 0.26 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) DUF5342 PF17277.2 CBY09438.1 - 0.13 12.6 0.1 0.47 10.8 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5342) TPR_2 PF07719.17 CBY09439.1 - 0.0034 17.4 5.4 0.18 12.0 0.5 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TGT PF01702.18 CBY09439.1 - 0.025 13.8 1.3 0.042 13.0 1.3 1.3 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase TPR_16 PF13432.6 CBY09439.1 - 0.047 14.3 0.1 0.12 13.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Acylphosphatase PF00708.18 CBY09440.1 - 1.4e-21 76.7 0.0 1.5e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase Cupin_8 PF13621.6 CBY09441.1 - 3.9e-15 56.3 0.4 3.7e-14 53.1 0.4 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY09441.1 - 3.3e-07 30.1 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 CBY09441.1 - 3.4e-07 30.7 0.1 1.5e-05 25.4 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CBY09441.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Cupin domain GPI PF06560.11 CBY09441.1 - 0.041 13.1 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) G_path_suppress PF15991.5 CBY09442.1 - 1.6e-16 61.3 10.4 2.1e-16 60.9 10.4 1.1 1 0 0 1 1 1 1 G-protein pathway suppressor V_ATPase_I PF01496.19 CBY09442.1 - 0.0045 15.0 9.1 0.0051 14.8 9.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FTA4 PF13093.6 CBY09442.1 - 0.012 15.5 8.9 0.017 15.0 8.9 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GAS PF13851.6 CBY09442.1 - 0.013 14.9 19.8 0.017 14.5 19.8 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fmp27_WPPW PF10359.9 CBY09442.1 - 0.032 13.1 12.0 0.038 12.9 12.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 CBY09442.1 - 0.064 12.3 13.5 0.079 12.0 13.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CBY09442.1 - 0.24 10.9 8.7 0.28 10.7 8.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SOBP PF15279.6 CBY09442.1 - 0.51 10.9 10.5 0.62 10.6 10.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Allexi_40kDa PF05549.11 CBY09442.1 - 0.52 9.8 5.1 0.47 9.9 4.2 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein PCRF PF03462.18 CBY09442.1 - 0.55 10.1 8.9 0.75 9.6 8.9 1.2 1 0 0 1 1 1 0 PCRF domain LCD1 PF09798.9 CBY09442.1 - 0.55 8.7 13.3 0.68 8.4 13.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Spc7 PF08317.11 CBY09442.1 - 1.2 8.0 19.1 1.5 7.6 19.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 CBY09442.1 - 1.4 7.4 9.8 2 6.9 9.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A FliD_N PF02465.18 CBY09442.1 - 2 9.2 8.0 3.5 8.4 7.9 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus 5_nucleotid PF05761.14 CBY09442.1 - 3.4 6.5 9.8 4.4 6.1 9.8 1.2 1 0 0 1 1 1 0 5' nucleotidase family zf-C4H2 PF10146.9 CBY09442.1 - 3.7 7.8 16.7 6.9 6.9 16.7 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein Nup88 PF10168.9 CBY09442.1 - 5.1 4.8 15.8 6.3 4.5 15.8 1.0 1 0 0 1 1 1 0 Nuclear pore component HAUS6_N PF14661.6 CBY09442.1 - 5.2 6.6 15.4 8.5 5.9 15.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ALMT PF11744.8 CBY09442.1 - 5.6 5.7 6.3 6.5 5.5 6.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0242 PF06785.11 CBY09442.1 - 8.6 6.4 19.2 12 5.9 19.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sugar_tr PF00083.24 CBY09443.1 - 1.9e-18 66.6 0.7 2.3e-18 66.3 0.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY09443.1 - 0.0013 17.7 5.5 0.0023 16.9 5.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PhoPQ_related PF10142.9 CBY09444.1 - 1.1e-22 80.3 0.0 1.4e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Sugar_tr PF00083.24 CBY09445.1 - 1.9e-37 129.2 4.2 2.4e-37 128.9 4.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY09445.1 - 1.3e-22 80.2 9.8 1.5e-22 80.0 9.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CBY09445.1 - 0.00077 18.1 2.9 0.00077 18.1 2.9 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 CBY09445.1 - 0.0024 16.4 1.9 0.0029 16.1 1.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PIRT PF15099.6 CBY09445.1 - 0.052 13.1 0.3 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family OATP PF03137.20 CBY09445.1 - 3.7 5.7 10.1 0.33 9.2 1.7 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RasGAP PF00616.19 CBY09446.1 - 2.6e-34 118.7 3.4 1e-33 116.8 0.0 3.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 CBY09446.1 - 2.8e-18 63.9 6.2 0.00027 20.5 0.0 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif RasGAP_C PF03836.15 CBY09446.1 - 4.2e-16 59.3 6.7 4.2e-16 59.3 6.7 2.5 3 0 0 3 3 3 1 RasGAP C-terminus CH PF00307.31 CBY09447.1 - 8.3e-13 48.5 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain PHY PF00360.20 CBY09447.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Phytochrome region Bombolitin PF08096.11 CBY09447.1 - 9.7 6.7 7.4 6.5 7.2 0.5 3.3 3 0 0 3 3 3 0 Bombolitin family GRAM PF02893.20 CBY09449.1 - 0.055 13.3 0.0 0.059 13.3 0.0 1.0 1 0 0 1 1 1 0 GRAM domain RNA_pol_A_bac PF01000.26 CBY09450.1 - 3.7e-28 98.1 0.2 5.5e-28 97.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBY09450.1 - 5e-09 35.5 0.0 6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RcpC PF16976.5 CBY09451.1 - 0.026 14.6 0.1 0.069 13.2 0.1 1.7 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB ABG_transport PF03806.13 CBY09451.1 - 0.047 11.9 0.0 0.06 11.6 0.0 1.1 1 0 0 1 1 1 0 AbgT putative transporter family Serine_rich PF08824.10 CBY09452.1 - 7.6e-39 133.2 0.7 7.6e-39 133.2 0.7 2.6 2 1 0 2 2 2 1 Serine rich protein interaction domain CAS_C PF12026.8 CBY09452.1 - 1.6e-11 44.7 4.4 1.6e-11 44.7 4.4 2.2 2 1 0 2 2 2 1 Crk-Associated Substrate C-terminal domain SH3_9 PF14604.6 CBY09452.1 - 2.3e-11 43.3 0.8 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY09452.1 - 5.3e-11 41.9 0.1 2.3e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CBY09452.1 - 4.6e-09 35.8 0.0 8.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PPI_Ypi1 PF07491.11 CBY09453.1 - 3.8e-22 77.9 0.1 3.8e-22 77.9 0.1 2.1 2 0 0 2 2 2 1 Protein phosphatase inhibitor DUF823 PF05689.11 CBY09453.1 - 0.038 13.7 0.1 0.21 11.3 0.1 1.8 1 1 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) Ribosomal_L4 PF00573.22 CBY09454.1 - 5.7e-13 49.0 0.0 8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF2012 PF09430.10 CBY09455.1 - 9.3e-21 74.2 0.2 1.4e-20 73.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF2846 PF11008.8 CBY09455.1 - 0.0024 17.9 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2846) fn3_3 PF14686.6 CBY09455.1 - 0.0038 17.0 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 CBY09455.1 - 0.0074 16.5 0.1 0.014 15.7 0.1 1.5 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF3007 PF11460.8 CBY09455.1 - 0.024 14.9 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) CarbopepD_reg_2 PF13715.6 CBY09455.1 - 0.046 13.7 0.1 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 CarboxypepD_reg-like domain zf-RING_2 PF13639.6 CBY09456.1 - 4.3e-07 30.1 10.3 1.2e-06 28.8 10.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY09456.1 - 3.4e-05 23.6 10.0 8.5e-05 22.3 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY09456.1 - 6.2e-05 22.9 9.8 0.00016 21.5 9.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY09456.1 - 0.00033 20.4 8.6 0.001 18.9 8.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY09456.1 - 0.00054 19.8 9.7 0.0014 18.4 9.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBY09456.1 - 0.0092 16.0 4.9 0.01 15.9 1.8 2.5 1 1 1 2 2 2 1 RING-type zinc-finger Unstab_antitox PF09720.10 CBY09456.1 - 0.022 14.8 1.5 0.022 14.8 1.5 2.6 2 0 0 2 2 2 0 Putative addiction module component Zn_ribbon_17 PF17120.5 CBY09456.1 - 0.22 11.1 7.8 0.52 10.0 7.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 CBY09456.1 - 0.38 10.7 13.5 0.07 13.0 9.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY09456.1 - 0.38 10.6 12.6 0.35 10.7 10.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain tRNA-synt_1_2 PF13603.6 CBY09456.1 - 0.9 9.0 8.9 5.1 6.6 1.3 3.0 2 1 1 3 3 3 0 Leucyl-tRNA synthetase, Domain 2 zf-rbx1 PF12678.7 CBY09456.1 - 1.2 9.5 13.1 0.41 11.0 8.9 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CBY09456.1 - 1.6 8.9 9.7 1.2 9.3 6.6 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 MCC-bdg_PDZ PF10506.9 CBY09456.1 - 2 8.5 9.0 0.24 11.4 0.6 3.6 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ank_2 PF12796.7 CBY09457.1 - 0.0021 18.6 0.3 0.0046 17.5 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY09457.1 - 0.0031 17.8 0.2 2.2 8.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY09457.1 - 0.0068 17.0 0.1 0.021 15.4 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY09457.1 - 0.56 10.9 2.1 17 6.4 0.0 3.8 5 0 0 5 5 5 0 Ankyrin repeat DUF1241 PF06840.11 CBY09458.1 - 1.9e-26 92.5 0.7 3e-26 91.9 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1241) CHASE3 PF05227.13 CBY09458.1 - 0.038 13.9 1.6 0.071 13.0 0.9 1.8 1 1 1 2 2 2 0 CHASE3 domain OKR_DC_1_N PF03709.15 CBY09458.1 - 0.046 14.0 0.1 0.091 13.0 0.1 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Syntaxin PF00804.25 CBY09458.1 - 0.059 13.0 3.7 0.17 11.6 3.7 1.8 1 1 0 1 1 1 0 Syntaxin DUF2385 PF09539.10 CBY09458.1 - 0.061 13.9 0.3 0.55 10.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2385) Colicin_immun PF09204.10 CBY09458.1 - 0.073 13.6 1.1 4.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Kelch_1 PF01344.25 CBY09459.1 - 3.7e-13 48.8 2.9 1.3e-06 27.9 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CBY09459.1 - 2e-07 31.0 3.8 0.015 15.6 0.2 5.3 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBY09459.1 - 3.3e-05 23.7 5.4 0.12 12.3 0.0 5.4 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.6 CBY09459.1 - 0.00011 22.2 6.5 3 7.9 0.1 5.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY09459.1 - 0.00053 19.9 0.6 52 4.0 0.0 5.0 5 0 0 5 5 5 0 Kelch motif DUF3847 PF12958.7 CBY09459.1 - 0.16 12.1 2.7 0.91 9.7 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) TEX12 PF15219.6 CBY09459.1 - 1.5 9.2 5.6 1.6 9.1 0.1 3.3 2 1 2 4 4 4 0 Testis-expressed 12 Kelch_3 PF13415.6 CBY09459.1 - 2.9 8.3 7.9 48 4.4 0.1 4.8 5 1 0 5 5 5 0 Galactose oxidase, central domain PGM_PMM_III PF02880.16 CBY09460.1 - 6.3e-21 74.7 0.0 8.3e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CBY09460.1 - 0.0039 17.8 0.4 0.0064 17.1 0.4 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Kinesin PF00225.23 CBY09461.1 - 2.8e-85 286.2 0.0 2.8e-85 286.2 0.0 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY09461.1 - 4.3e-21 75.4 2.1 5.9e-19 68.5 0.0 3.3 3 0 0 3 3 3 1 Microtubule binding zf-C2H2_4 PF13894.6 CBY09461.1 - 1.3e-10 41.2 18.3 0.014 16.2 0.4 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY09461.1 - 6.6e-10 38.9 22.3 0.0079 16.6 0.7 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY09461.1 - 4.4e-07 30.0 0.6 4.4e-07 30.0 0.6 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 CBY09461.1 - 0.022 15.1 11.4 0.024 15.1 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Spc7 PF08317.11 CBY09461.1 - 0.035 13.0 85.6 0.0067 15.3 18.8 4.9 1 1 3 5 5 5 0 Spc7 kinetochore protein zf-C2H2_11 PF16622.5 CBY09461.1 - 0.043 13.6 5.0 0.37 10.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 CBY09461.1 - 0.18 12.3 2.1 18 5.9 0.1 3.0 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_jaz PF12171.8 CBY09461.1 - 0.28 11.5 3.9 1.3 9.4 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 CBY09461.1 - 0.34 11.0 4.6 3 7.9 0.3 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_2 PF12756.7 CBY09461.1 - 0.65 10.4 9.5 51 4.3 3.8 4.7 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF4407 PF14362.6 CBY09461.1 - 1.5 8.1 57.1 0.92 8.8 9.3 4.2 1 1 2 3 3 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CBY09461.1 - 4.7 7.3 74.4 0.56 10.3 7.5 6.4 3 3 3 6 6 6 0 Afadin- and alpha -actinin-Binding zf-C2HC_2 PF13913.6 CBY09461.1 - 6 6.9 8.9 2 8.4 0.6 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Pkinase PF00069.25 CBY09462.1 - 6.3e-15 55.2 0.0 1.6e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY09462.1 - 3.8e-06 26.0 0.0 3.8e-06 26.0 0.0 3.0 2 1 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CBY09462.1 - 1.1e-05 24.9 0.0 2.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY09462.1 - 0.00039 19.8 0.0 0.00088 18.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 CBY09463.1 - 5.1e-49 166.0 0.0 5.9e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY09463.1 - 2.3e-30 105.3 0.0 4.6e-30 104.3 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY09463.1 - 3e-10 39.8 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY09463.1 - 0.00016 21.7 0.0 0.00025 21.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBY09463.1 - 0.00018 21.8 0.1 0.00093 19.6 0.1 2.0 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CBY09463.1 - 0.0036 17.0 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CBY09463.1 - 0.0044 16.4 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY09463.1 - 0.0081 15.7 0.2 0.031 13.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DAP3 PF10236.9 CBY09463.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ArgoMid PF16487.5 CBY09463.1 - 0.016 15.4 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute G-alpha PF00503.20 CBY09463.1 - 0.018 14.2 1.0 1.9 7.6 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 CBY09463.1 - 0.026 14.4 0.1 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 CBY09463.1 - 0.035 13.6 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 CBY09463.1 - 0.057 12.7 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CBY09463.1 - 0.068 13.5 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CBY09463.1 - 0.099 12.6 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBY09463.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region tRNA-synt_2 PF00152.20 CBY09464.1 - 2e-100 335.9 0.0 2.9e-100 335.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBY09464.1 - 6.1e-11 42.1 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 CBY09464.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Hc1 PF07432.13 CBY09464.1 - 0.12 12.7 10.9 0.66 10.3 10.5 2.1 2 0 0 2 2 2 0 Histone H1-like protein Hc1 Mg_trans_NIPA PF05653.14 CBY09465.1 - 5.4e-27 94.7 4.9 6.8e-27 94.3 4.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA Mg_trans_NIPA PF05653.14 CBY09466.1 - 4.1e-21 75.4 9.4 2.3e-19 69.6 9.4 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CBY09466.1 - 2.2e-11 44.1 11.3 3.3e-08 33.8 3.6 2.0 1 1 1 2 2 2 2 EamA-like transporter family zf-C2H2_jaz PF12171.8 CBY09467.1 - 0.00017 21.8 0.1 0.00043 20.5 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY09467.1 - 0.00035 20.9 1.3 0.00082 19.7 0.5 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CTP_transf_like PF01467.26 CBY09468.1 - 1.2e-38 132.5 0.1 2.7e-22 79.5 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like ScdA_N PF04405.14 CBY09468.1 - 0.091 12.4 0.1 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) FAD_syn PF06574.12 CBY09468.1 - 1.2 9.0 6.5 2.5 8.0 0.8 3.3 3 1 0 3 3 3 0 FAD synthetase Arm PF00514.23 CBY09469.1 - 7.4e-34 114.7 0.0 6.8e-13 48.2 0.0 7.3 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CBY09469.1 - 9.4e-15 53.9 0.8 9.4e-15 53.9 0.8 1.8 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 CBY09469.1 - 4.6e-10 39.8 6.5 1.6e-09 38.1 6.1 2.1 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.6 CBY09469.1 - 9.1e-08 32.5 0.0 0.3 11.7 0.0 5.2 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 CBY09469.1 - 3.2e-05 23.8 0.0 0.28 11.5 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 CBY09469.1 - 0.00057 20.0 0.0 0.056 13.5 0.0 3.1 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY09469.1 - 0.00087 19.6 0.1 0.018 15.4 0.0 3.0 3 1 0 3 3 3 1 HEAT repeats Atx10homo_assoc PF09759.9 CBY09469.1 - 0.0016 18.4 0.4 0.042 13.9 0.0 2.8 2 1 1 3 3 3 2 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 CBY09469.1 - 0.025 14.8 0.1 0.39 11.0 0.0 2.9 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3887 PF13026.6 CBY09469.1 - 0.14 13.0 0.0 0.36 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) DUF4709 PF15821.5 CBY09471.1 - 0.039 14.2 0.9 0.039 14.2 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) Myb_DNA-bind_7 PF15963.5 CBY09471.1 - 0.066 13.1 0.6 0.066 13.1 0.6 2.1 1 1 1 2 2 2 0 Myb DNA-binding like ARGLU PF15346.6 CBY09471.1 - 0.25 11.2 8.6 0.44 10.4 8.6 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 CCDC-167 PF15188.6 CBY09471.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 eIF-3_zeta PF05091.12 CBY09471.1 - 0.77 8.7 17.5 1.2 8.1 17.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LMBR1 PF04791.16 CBY09471.1 - 1.7 7.5 6.7 1.6 7.5 6.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Rootletin PF15035.6 CBY09473.1 - 0.00051 20.1 5.2 0.00051 20.1 5.2 1.8 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion EVC2_like PF12297.8 CBY09473.1 - 0.25 10.0 6.0 0.36 9.5 6.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Pkinase PF00069.25 CBY09474.1 - 1.5e-39 136.0 0.1 1.8e-39 135.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09474.1 - 2e-28 99.4 0.0 2.3e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY09474.1 - 0.00087 18.3 0.1 0.0057 15.6 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CBY09474.1 - 0.0015 17.7 0.1 0.0036 16.4 0.0 1.6 1 1 1 2 2 2 1 Seadornavirus VP7 APH PF01636.23 CBY09474.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY09474.1 - 0.044 13.1 0.1 0.081 12.2 0.0 1.4 2 0 0 2 2 2 0 Kinase-like AAA PF00004.29 CBY09475.1 - 1.2e-29 103.4 0.1 1.8e-28 99.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBY09475.1 - 3.1e-05 23.8 0.0 7e-05 22.6 0.0 1.5 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBY09475.1 - 8.3e-05 23.0 0.1 0.0048 17.3 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBY09475.1 - 8.4e-05 22.9 0.2 0.057 13.7 0.1 3.2 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 CBY09475.1 - 0.00038 20.6 0.1 0.0013 18.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CBY09475.1 - 0.00058 20.0 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBY09475.1 - 0.00091 19.3 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CBY09475.1 - 0.0029 17.6 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CBY09475.1 - 0.0031 16.8 0.0 0.0066 15.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CBY09475.1 - 0.0042 17.1 0.1 0.032 14.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBY09475.1 - 0.0048 16.3 0.0 0.0099 15.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBY09475.1 - 0.0078 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Parvo_NS1 PF01057.17 CBY09475.1 - 0.022 13.9 0.2 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 CBY09475.1 - 0.027 14.0 0.1 0.064 12.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBY09475.1 - 0.03 14.7 0.0 0.073 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 CBY09475.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CBY09475.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 CBY09475.1 - 0.11 11.9 0.0 2.4 7.5 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.6 CBY09475.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.9 2 1 0 2 2 1 0 AAA domain SRPRB PF09439.10 CBY09475.1 - 0.23 10.9 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 1 0 Signal recognition particle receptor beta subunit IBR PF01485.21 CBY09475.1 - 0.34 11.2 2.5 0.29 11.4 0.3 2.0 2 0 0 2 2 1 0 IBR domain, a half RING-finger domain AIF_C PF14721.6 CBY09475.1 - 2.7 8.4 4.9 0.5 10.7 1.2 1.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hydin_ADK PF17213.3 CBY09475.1 - 8.9 6.5 6.4 4 7.7 0.0 2.5 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain BRCA-2_OB1 PF09103.10 CBY09477.1 - 1.7e-18 66.8 0.4 4.8e-17 62.1 0.2 3.3 2 1 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 CBY09477.1 - 2.7e-08 33.7 2.2 4.5e-08 33.0 0.0 2.4 2 1 0 2 2 2 1 BRCA2, helical BRCA-2_OB3 PF09104.10 CBY09477.1 - 7.4e-07 28.9 0.1 2e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Av_adeno_fibre PF06536.11 CBY09477.1 - 0.024 14.5 0.2 0.57 10.1 0.1 2.4 2 0 0 2 2 2 0 Avian adenovirus fibre, N-terminal BRCA2 PF00634.18 CBY09477.1 - 0.077 12.7 18.2 2.2 8.0 0.0 5.9 7 0 0 7 7 7 0 BRCA2 repeat Transformer PF06495.11 CBY09478.1 - 0.0067 16.5 10.6 0.0071 16.5 10.6 1.2 1 0 0 1 1 1 1 Fruit fly transformer protein EF-hand_1 PF00036.32 CBY09480.1 - 2.6e-19 67.2 13.6 6.8e-06 25.3 0.6 6.3 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 CBY09480.1 - 2.9e-17 61.0 10.7 6.4e-06 25.7 0.1 6.2 6 0 0 6 6 6 5 EF-hand domain EF-hand_7 PF13499.6 CBY09480.1 - 4.2e-16 59.2 22.5 2.5e-06 27.8 1.7 4.9 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 CBY09480.1 - 6.5e-14 50.7 13.4 0.0055 16.2 0.7 6.0 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 CBY09480.1 - 0.0015 18.3 20.7 0.35 10.8 0.9 6.1 5 2 0 5 5 5 3 EF-hand domain pair Spa1_C PF18218.1 CBY09480.1 - 0.019 15.3 0.1 0.049 14.0 0.1 1.6 1 0 0 1 1 1 0 Lantibiotic immunity protein Spa1 C-terminal domain SPARC_Ca_bdg PF10591.9 CBY09480.1 - 0.074 13.4 12.1 0.32 11.3 0.2 3.2 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Borrelia_REV PF03978.13 CBY09480.1 - 0.42 10.6 6.7 0.078 12.9 0.9 2.1 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein Excalibur PF05901.11 CBY09480.1 - 0.45 11.2 1.7 1e+02 3.6 0.0 4.0 4 0 0 4 4 4 0 Excalibur calcium-binding domain PHO4 PF01384.20 CBY09481.1 - 9.4e-115 383.2 10.5 1.2e-114 382.9 10.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family GCV_H PF01597.19 CBY09483.1 - 2.8e-44 149.9 0.5 3.4e-44 149.7 0.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 CBY09483.1 - 8.7e-06 25.6 0.1 1.3e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 CBY09483.1 - 4.9e-05 23.1 3.0 8.8e-05 22.3 2.2 1.8 1 1 1 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBY09483.1 - 0.061 13.1 1.3 3.9 7.4 0.2 2.8 2 1 1 3 3 3 0 Biotin-lipoyl like AAA PF00004.29 CBY09484.1 - 5.6e-95 314.8 0.0 7.6e-47 159.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY09484.1 - 7.6e-22 76.9 3.9 7.4e-10 38.5 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CBY09484.1 - 9.1e-19 67.4 0.5 1.5e-17 63.6 0.3 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CBY09484.1 - 6.7e-14 51.9 0.0 2.2e-05 24.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBY09484.1 - 3.7e-12 47.0 0.2 0.00064 20.1 0.0 3.9 2 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 CBY09484.1 - 7.8e-12 45.6 0.0 3.6e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CBY09484.1 - 9.9e-11 42.0 0.0 5.3e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CBY09484.1 - 2.9e-10 40.3 0.1 8e-05 22.7 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY09484.1 - 8.4e-10 39.1 0.3 0.01 16.1 0.1 3.8 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 CBY09484.1 - 3.9e-09 36.2 0.0 0.00038 19.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 CBY09484.1 - 2e-08 34.4 0.0 0.0025 17.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 CBY09484.1 - 8.2e-08 32.1 0.6 2.3e-05 24.3 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 CBY09484.1 - 1e-07 32.5 0.0 0.016 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CBY09484.1 - 3.4e-07 29.9 0.1 0.021 14.2 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBY09484.1 - 3.5e-07 30.1 0.1 0.039 13.7 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein CDC48_2 PF02933.17 CBY09484.1 - 4e-07 29.7 0.0 8.6e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.22 CBY09484.1 - 6.7e-07 29.7 0.0 0.0068 16.8 0.0 2.8 3 0 0 3 3 2 2 RNA helicase ABC_tran PF00005.27 CBY09484.1 - 5.4e-06 27.0 0.0 0.0045 17.5 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 CBY09484.1 - 6.7e-06 25.7 0.0 0.066 12.7 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 CBY09484.1 - 7.7e-06 26.2 0.0 0.19 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 CBY09484.1 - 1.2e-05 24.8 1.2 1.9 7.8 0.0 3.6 4 0 0 4 4 3 2 KaiC Parvo_NS1 PF01057.17 CBY09484.1 - 1.3e-05 24.4 0.1 0.035 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 CBY09484.1 - 1.5e-05 25.0 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_17 PF13207.6 CBY09484.1 - 1.7e-05 25.2 0.0 0.73 10.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 CBY09484.1 - 3.6e-05 23.4 1.9 1.8 8.1 0.0 3.7 2 2 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 CBY09484.1 - 5.6e-05 22.9 0.0 0.45 10.2 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CBY09484.1 - 6.9e-05 22.7 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CBY09484.1 - 7e-05 22.6 0.0 0.2 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CBY09484.1 - 8.4e-05 22.6 0.2 0.2 11.5 0.0 3.6 3 2 1 4 4 3 1 ATPase domain predominantly from Archaea TsaE PF02367.17 CBY09484.1 - 0.00013 22.0 0.0 0.28 11.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CBY09484.1 - 0.00019 20.7 0.0 0.033 13.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 CBY09484.1 - 0.00026 20.3 0.0 0.52 9.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin ResIII PF04851.15 CBY09484.1 - 0.00031 20.8 0.0 0.064 13.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 CBY09484.1 - 0.00051 20.2 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 CBY09484.1 - 0.00054 19.9 0.1 0.29 11.0 0.0 3.3 3 1 1 4 4 4 1 NACHT domain PhoH PF02562.16 CBY09484.1 - 0.00057 19.4 0.5 1 8.7 0.2 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 CBY09484.1 - 0.00062 19.6 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CBY09484.1 - 0.00067 18.9 0.0 0.15 11.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain UFD1 PF03152.14 CBY09484.1 - 0.0018 17.8 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF2075 PF09848.9 CBY09484.1 - 0.0028 17.0 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CBY09484.1 - 0.0042 17.4 0.3 2.7 8.3 0.3 2.8 2 1 1 3 3 2 1 AAA domain NTPase_1 PF03266.15 CBY09484.1 - 0.0043 17.0 1.1 5.3 6.9 0.0 4.2 3 1 0 4 4 4 0 NTPase AAA_11 PF13086.6 CBY09484.1 - 0.005 16.7 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 CBY09484.1 - 0.0054 16.9 0.0 0.72 10.0 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Rad17 PF03215.15 CBY09484.1 - 0.0061 16.5 0.0 0.95 9.4 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 CBY09484.1 - 0.033 13.9 0.4 5.1 6.8 0.2 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CBY09484.1 - 0.051 13.3 0.0 3.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SKI PF01202.22 CBY09484.1 - 0.057 13.5 0.0 8.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 CBY09484.1 - 0.072 12.8 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase TniB PF05621.11 CBY09484.1 - 0.078 12.4 0.0 14 5.0 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein T2SSE PF00437.20 CBY09484.1 - 0.078 12.0 0.0 5.5 6.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Romo1 PF10247.9 CBY09485.1 - 4.7e-14 52.5 18.1 5.9e-14 52.2 18.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 CBY09485.1 - 0.0032 17.8 8.0 0.0036 17.7 8.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3169 PF11368.8 CBY09485.1 - 2.9 7.3 6.2 3.8 7.0 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) PCNA_N PF00705.18 CBY09486.1 - 0.0056 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Hydrolase_4 PF12146.8 CBY09489.1 - 1.6e-29 102.9 0.0 2.5e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY09489.1 - 8.6e-06 25.6 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY09489.1 - 9e-05 23.2 0.0 0.00013 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CBY09489.1 - 0.015 15.2 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 CBY09489.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 CBY09489.1 - 0.055 13.1 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_5 PF12695.7 CBY09489.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family TcpE PF12648.7 CBY09490.1 - 0.077 13.5 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 TcpE family 7tm_1 PF00001.21 CBY09491.1 - 2e-41 142.1 15.9 2.8e-41 141.6 15.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CBY09491.1 - 1.5e-08 34.6 23.4 1.5e-08 34.6 23.4 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CBY09491.1 - 1.2e-05 24.9 20.0 0.0026 17.2 16.5 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CBY09491.1 - 3.9e-05 23.5 15.1 0.00073 19.4 10.7 2.2 2 0 0 2 2 2 2 Olfactory receptor DUF973 PF06157.11 CBY09491.1 - 0.31 10.1 4.1 7.9 5.4 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF973) La PF05383.17 CBY09493.1 - 1.2e-15 57.3 0.3 3.4e-15 55.8 0.3 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY09493.1 - 0.016 15.0 0.9 4.7 7.1 0.9 2.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-1_beta_acid PF10587.9 CBY09493.1 - 0.41 11.1 2.2 1.2 9.6 2.2 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region TFIIA PF03153.13 CBY09493.1 - 0.91 9.5 8.8 1.6 8.6 8.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit POTRA_2 PF08479.11 CBY09494.1 - 0.026 14.4 0.0 0.068 13.0 0.0 1.7 2 0 0 2 2 2 0 POTRA domain, ShlB-type Adap_comp_sub PF00928.21 CBY09496.1 - 6.5e-40 137.2 0.1 7.7e-40 136.9 0.1 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 CBY09496.1 - 0.00095 18.7 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain CSN8_PSD8_EIF3K PF10075.9 CBY09497.1 - 5.7e-22 78.3 0.1 7.2e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CBY09497.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 SAC3/GANP family WAC_Acf1_DNA_bd PF10537.9 CBY09497.1 - 0.075 13.6 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal Lung_7-TM_R PF06814.13 CBY09498.1 - 1.3e-83 280.6 12.9 1.8e-83 280.2 12.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SPT6_acidic PF14632.6 CBY09498.1 - 0.0025 18.4 2.3 0.0025 18.4 2.3 2.3 2 0 0 2 2 2 1 Acidic N-terminal SPT6 DUF3671 PF12420.8 CBY09498.1 - 0.55 10.3 6.8 0.17 11.9 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function Peptidase_S39 PF02122.15 CBY09499.1 - 0.02 14.4 0.3 12 5.4 0.0 3.0 3 0 0 3 3 3 0 Peptidase S39 Branch PF02485.21 CBY09500.1 - 1.6e-39 135.9 2.3 2.6e-39 135.2 2.3 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Xylo_C PF12529.8 CBY09500.1 - 2.4e-15 56.6 0.0 4.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Xylosyltransferase C terminal LRR_4 PF12799.7 CBY09501.1 - 8.3e-43 143.7 62.8 2.7e-08 34.0 4.6 6.8 2 1 10 12 12 12 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY09501.1 - 3.7e-21 75.4 22.6 2.1e-09 37.1 3.2 4.5 1 1 4 5 5 5 5 Leucine-rich repeat LRR_8 PF13855.6 CBY09501.1 - 2e-17 62.7 26.0 7.2e-08 32.1 4.5 6.5 4 2 2 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 CBY09501.1 - 0.00017 21.4 20.6 0.3 11.2 0.4 7.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 CBY09501.1 - 0.023 15.2 25.3 5.7 7.9 0.9 8.7 8 2 1 9 9 9 0 Leucine Rich Repeat DUF2322 PF10084.9 CBY09501.1 - 0.089 12.8 3.9 1.7 8.8 0.1 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) UB2H PF14814.6 CBY09501.1 - 0.19 11.8 0.5 44 4.2 0.0 3.7 2 1 3 5 5 5 0 Bifunctional transglycosylase second domain MIP-T3 PF10243.9 CBY09502.1 - 9.7e-43 144.7 1.0 9.7e-43 144.7 1.0 3.3 2 2 1 3 3 3 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 CBY09502.1 - 5.2e-17 62.2 13.5 5.2e-17 62.2 13.5 3.9 3 1 1 4 4 4 1 Microtubule-binding protein MIP-T3 C-terminal region MeaB PF03308.16 CBY09503.1 - 7.7e-85 284.1 0.0 8.6e-85 283.9 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CBY09503.1 - 0.00015 21.6 0.0 0.00046 20.0 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 CBY09503.1 - 0.0018 17.9 0.1 0.0072 15.9 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CBY09503.1 - 0.0026 17.5 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY09503.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBY09503.1 - 0.018 15.6 0.1 0.038 14.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter CitG PF01874.16 CBY09503.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.3 1 1 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase AAA_18 PF13238.6 CBY09503.1 - 0.031 14.8 1.4 0.053 14.1 0.1 2.1 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CBY09503.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CBY09503.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 CBY09503.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 CBY09503.1 - 0.066 13.3 0.0 0.2 11.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 CBY09503.1 - 0.13 11.5 0.0 0.28 10.4 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Thymidylate_kin PF02223.17 CBY09503.1 - 0.14 11.8 0.2 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Thymidylate kinase AAA PF00004.29 CBY09503.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBY09503.1 - 0.15 12.1 0.6 8.8 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CBY09503.1 - 0.17 12.2 0.0 0.22 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain PDZ PF00595.24 CBY09504.1 - 1.8e-10 41.1 0.0 4.4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY09504.1 - 7.8e-07 28.9 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY09504.1 - 3.1e-06 27.4 0.0 1.2e-05 25.5 0.0 2.0 1 0 0 1 1 1 1 PDZ domain AT_hook PF02178.19 CBY09504.1 - 0.84 9.7 3.9 3.5 7.8 3.9 2.2 1 0 0 1 1 1 0 AT hook motif Pribosyltran PF00156.27 CBY09505.1 - 1.5e-15 57.0 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBY09505.1 - 0.0057 16.1 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CBY09505.1 - 0.03 13.8 0.1 0.066 12.7 0.1 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase AMP-binding PF00501.28 CBY09506.1 - 5.3e-97 325.1 0.0 7.1e-97 324.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY09506.1 - 0.1 13.6 0.7 0.55 11.3 0.7 2.3 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 CBY09507.1 - 1.8e-60 204.5 0.0 2.8e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09507.1 - 6.2e-33 114.2 0.0 9.8e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CSL PF05207.13 CBY09507.1 - 3.9e-23 80.9 4.6 8.2e-22 76.7 2.0 2.7 2 0 0 2 2 2 1 CSL zinc finger Kinase-like PF14531.6 CBY09507.1 - 9.5e-07 28.4 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY09507.1 - 0.00037 20.5 0.0 0.00089 19.2 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY09507.1 - 0.0064 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY09507.1 - 0.0083 15.7 0.0 0.024 14.2 0.0 1.7 1 1 0 1 1 1 1 RIO1 family Zn-ribbon_8 PF09723.10 CBY09507.1 - 0.012 15.7 4.1 0.033 14.3 0.4 2.6 2 0 0 2 2 2 0 Zinc ribbon domain KA1 PF02149.19 CBY09507.1 - 0.071 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Kinase associated domain 1 RhoGEF PF00621.20 CBY09508.1 - 8e-17 62.1 10.1 1.6e-10 41.5 1.1 3.1 2 1 1 3 3 3 2 RhoGEF domain Syntaxin-6_N PF09177.11 CBY09508.1 - 0.16 12.6 8.3 1.6 9.3 0.0 3.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal ETRAMP PF09716.10 CBY09508.1 - 2.9 8.0 0.0 2.9 8.0 0.0 3.5 3 2 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF1947 PF09183.10 CBY09508.1 - 4.6 7.6 7.0 8.5 6.8 1.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) DUF908 PF06012.12 CBY09509.1 - 0.29 10.5 6.4 0.39 10.1 6.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) AAA_11 PF13086.6 CBY09509.1 - 0.37 10.5 12.2 0.52 10.1 12.2 1.1 1 0 0 1 1 1 0 AAA domain DUF3381 PF11861.8 CBY09509.1 - 0.42 10.4 20.5 0.71 9.7 20.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Borrelia_P83 PF05262.11 CBY09509.1 - 0.84 8.1 18.4 1.1 7.7 18.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein IHABP4_N PF16174.5 CBY09509.1 - 0.95 10.0 19.7 2.1 9.0 19.7 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF3807 PF12720.7 CBY09509.1 - 1.1 9.6 14.3 1.8 8.8 14.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Zip PF02535.22 CBY09509.1 - 3.9 6.6 4.2 5.2 6.2 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CBY09509.1 - 5 7.1 5.7 7 6.6 5.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FancD2 PF14631.6 CBY09509.1 - 6.1 4.1 8.5 7.7 3.8 8.5 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Chitin_synth_2 PF03142.15 CBY09510.1 - 3.3e-23 82.1 0.2 3.3e-23 82.1 0.2 2.8 2 1 1 3 3 3 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CBY09510.1 - 7.9e-09 35.7 0.1 1.5e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY09510.1 - 8.4e-09 35.6 8.9 8.4e-09 35.6 8.9 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CBY09510.1 - 0.0082 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 PX PF00787.24 CBY09512.1 - 3.6e-22 78.5 0.1 6.3e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 CBY09512.1 - 2.3e-14 52.7 0.4 5.1e-14 51.6 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CBY09512.1 - 1.4e-10 40.8 0.1 2.8e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY09512.1 - 2.9e-10 39.7 0.0 8e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain BAR_3_WASP_bdg PF10456.9 CBY09513.1 - 4.3e-23 82.0 0.1 4.8e-23 81.8 0.1 1.0 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Astacin PF01400.24 CBY09514.1 - 7.3e-23 81.2 0.3 4e-21 75.5 0.3 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY09514.1 - 0.0047 17.1 2.6 0.016 15.4 2.6 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Aldose_epim PF01263.20 CBY09516.1 - 1.4e-69 234.7 0.1 1.6e-69 234.5 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4751 PF15942.5 CBY09516.1 - 0.11 12.5 0.8 0.4 10.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4751) Lectin_C PF00059.21 CBY09517.1 - 8.1e-05 23.3 1.3 0.00048 20.8 0.0 2.4 3 0 0 3 3 3 1 Lectin C-type domain DUF5010_C PF18099.1 CBY09517.1 - 0.0094 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 DUF5010 C-terminal domain IP_trans PF02121.18 CBY09518.1 - 3.8e-63 213.4 6.5 4.6e-63 213.1 6.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein TPR_19 PF14559.6 CBY09520.1 - 1.6e-18 66.9 0.0 4.5e-07 30.3 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY09520.1 - 1.6e-10 40.9 0.0 0.051 14.4 0.0 5.3 2 1 3 5 5 5 3 Tetratricopeptide repeat S1 PF00575.23 CBY09520.1 - 1.3e-07 31.8 0.8 0.00025 21.3 0.0 3.1 2 1 0 2 2 2 2 S1 RNA binding domain TPR_16 PF13432.6 CBY09520.1 - 1.8e-07 31.7 0.0 0.012 16.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY09520.1 - 0.00028 20.2 0.1 0.083 12.1 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 CBY09520.1 - 0.0017 18.1 0.1 0.0042 16.8 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 CBY09520.1 - 0.0031 17.6 0.1 15 6.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY09520.1 - 0.004 17.4 0.0 21 5.8 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY09520.1 - 0.0083 16.4 0.0 29 5.1 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY09520.1 - 0.01 15.9 0.0 3.1 8.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY09520.1 - 0.014 15.6 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY09520.1 - 0.029 13.8 0.6 0.74 9.1 0.1 2.5 1 1 1 2 2 2 0 MalT-like TPR region ChAPs PF09295.10 CBY09520.1 - 0.036 13.1 0.0 3.1 6.7 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CBY09520.1 - 0.052 14.2 0.1 59 4.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.14 CBY09520.1 - 0.8 9.6 4.7 20 5.0 0.0 3.4 1 1 2 4 4 4 0 Suppressor of forked protein (Suf) DUF2031 PF09592.10 CBY09520.1 - 5.5 6.4 8.7 0.13 11.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) ENTH PF01417.20 CBY09523.1 - 3.8e-41 140.0 0.0 6e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DNA_pol_A_exo1 PF01612.20 CBY09524.1 - 2.6e-12 46.8 0.0 8.3e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Stc1 PF12898.7 CBY09524.1 - 0.053 14.1 1.1 0.12 13.0 1.1 1.6 1 0 0 1 1 1 0 Stc1 domain Tnp_zf-ribbon_2 PF13842.6 CBY09524.1 - 1.2 10.0 5.0 1.6 9.6 2.0 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon PEN-2 PF10251.9 CBY09525.1 - 0.0003 21.1 3.5 0.00031 21.1 1.3 2.1 2 0 0 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase Phospholip_A2_1 PF00068.19 CBY09527.1 - 4.9e-09 36.7 0.6 4.9e-09 36.7 0.6 1.7 2 0 0 2 2 2 1 Phospholipase A2 Lectin_C PF00059.21 CBY09528.1 - 2.6e-46 156.8 20.9 1.9e-14 54.3 0.4 4.5 4 0 0 4 4 4 4 Lectin C-type domain Trefoil PF00088.18 CBY09528.1 - 2.7e-05 23.9 5.3 0.00011 22.0 5.3 2.1 1 0 0 1 1 1 1 Trefoil (P-type) domain UL45 PF05473.12 CBY09528.1 - 0.1 12.2 3.4 13 5.3 0.0 3.2 3 0 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like MORN PF02493.20 CBY09528.1 - 0.49 10.4 2.5 2.7 8.1 0.1 3.5 4 0 0 4 4 4 0 MORN repeat ING PF12998.7 CBY09529.1 - 3.4e-09 37.2 4.0 4.8e-09 36.7 4.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CBY09529.1 - 1.9e-05 24.5 9.9 3.2e-05 23.7 9.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY09529.1 - 0.0083 15.7 1.0 0.014 14.9 1.0 1.4 1 0 0 1 1 1 1 PHD-finger CENP-Q PF13094.6 CBY09529.1 - 0.014 15.6 2.9 0.019 15.2 2.9 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-HC5HC2H PF13771.6 CBY09529.1 - 0.049 13.9 0.5 0.049 13.9 0.5 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain FlaC_arch PF05377.11 CBY09529.1 - 4.8 7.7 7.1 4.5 7.7 0.3 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2614 PF11023.8 CBY09530.1 - 1.4 9.0 9.8 11 6.2 3.7 2.8 2 1 0 2 2 2 0 Zinc-ribbon containing domain CSRNP_N PF16019.5 CBY09531.1 - 2e-72 243.6 8.6 2e-72 243.6 8.6 1.8 2 0 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus ITI_HC_C PF06668.12 CBY09532.1 - 0.00045 19.9 0.7 0.00077 19.2 0.0 1.7 2 1 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus ITI_HC_C PF06668.12 CBY09533.1 - 0.00018 21.2 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Clat_adaptor_s PF01217.20 CBY09534.1 - 2.5e-58 196.1 4.6 2.7e-58 195.9 4.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3318 PF11780.8 CBY09535.1 - 0.085 12.8 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DUF533 PF04391.12 CBY09535.1 - 0.1 12.1 0.1 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DDE_Tnp_IS1 PF03400.13 CBY09536.1 - 0.027 14.8 0.1 0.042 14.2 0.1 1.3 1 0 0 1 1 1 0 IS1 transposase BOFC_N PF08977.10 CBY09536.1 - 0.062 13.3 2.0 0.12 12.4 2.0 1.4 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal Orf78 PF06024.12 CBY09538.1 - 0.13 12.6 0.1 0.55 10.6 0.1 2.1 1 0 0 1 1 1 0 Orf78 (ac78) Kelch_6 PF13964.6 CBY09539.1 - 9.5e-06 25.7 2.6 6.9 7.1 0.0 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CBY09539.1 - 0.00017 21.4 0.5 7.6 6.7 0.2 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CBY09539.1 - 0.0018 17.8 0.1 0.82 9.3 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CBY09539.1 - 0.051 13.6 2.3 5.2 7.2 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Dynamin_M PF01031.20 CBY09540.1 - 5.3e-92 308.1 11.2 5.3e-92 308.1 11.2 2.2 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CBY09540.1 - 2.2e-56 190.5 0.0 8.2e-56 188.7 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CBY09540.1 - 2.7e-25 88.4 4.7 1.2e-24 86.3 4.7 2.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 CBY09540.1 - 1.1e-05 25.9 0.3 2.4e-05 24.8 0.3 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 CBY09540.1 - 8.3e-05 22.6 0.0 0.00047 20.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RecG_N PF17190.4 CBY09540.1 - 0.48 11.2 4.2 0.84 10.4 0.5 3.3 2 1 1 3 3 3 0 RecG N-terminal helical domain ELFV_dehydrog PF00208.21 CBY09541.1 - 1.2e-73 247.8 0.1 1.5e-73 247.5 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CBY09541.1 - 5.2e-52 175.1 0.0 1.1e-51 174.1 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SHE3 PF17078.5 CBY09542.1 - 0.00012 21.9 4.1 0.00012 21.9 4.1 2.0 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 HAP1_N PF04849.13 CBY09542.1 - 0.00015 21.1 4.0 0.001 18.4 1.5 2.1 2 0 0 2 2 2 1 HAP1 N-terminal conserved region TMF_TATA_bd PF12325.8 CBY09542.1 - 0.00062 20.0 1.9 0.029 14.6 0.2 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 CBY09542.1 - 0.012 15.9 5.0 3.9 7.8 0.0 3.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 CBY09542.1 - 0.021 14.2 3.0 0.053 12.9 1.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.9 CBY09542.1 - 0.035 13.1 2.6 0.24 10.3 1.2 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 EzrA PF06160.12 CBY09542.1 - 0.036 12.3 7.4 0.025 12.8 4.7 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Effector_1 PF04518.12 CBY09542.1 - 0.071 12.2 1.9 0.16 11.0 0.8 1.8 2 0 0 2 2 2 0 Effector from type III secretion system SF-assemblin PF06705.11 CBY09542.1 - 0.16 11.3 1.3 0.36 10.1 0.3 1.8 2 0 0 2 2 2 0 SF-assemblin/beta giardin UPF0242 PF06785.11 CBY09542.1 - 0.17 11.9 7.8 1.2 9.1 7.8 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin PF00804.25 CBY09542.1 - 0.19 11.3 1.4 1 9.0 0.2 2.1 2 0 0 2 2 2 0 Syntaxin HALZ PF02183.18 CBY09542.1 - 0.23 11.7 4.8 0.37 11.1 0.3 3.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper TMPIT PF07851.13 CBY09542.1 - 0.31 10.2 5.6 2.3 7.4 1.8 2.3 1 1 0 2 2 2 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 CBY09542.1 - 0.63 10.1 5.9 0.47 10.5 3.6 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SLATT_5 PF18160.1 CBY09542.1 - 0.92 8.8 7.2 0.42 9.9 2.9 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PI3K_P85_iSH2 PF16454.5 CBY09542.1 - 5.5 6.6 12.5 0.17 11.5 2.0 2.9 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Paramyxo_ncap PF00973.19 CBY09543.1 - 2.6 6.9 7.2 3.7 6.4 7.2 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.14 CBY09543.1 - 3.4 5.8 16.3 4.8 5.4 16.3 1.2 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.16 CBY09543.1 - 3.6 6.4 6.2 4.6 6.0 6.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Astacin PF01400.24 CBY09546.1 - 1.9e-52 177.7 0.0 2.9e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CBY09546.1 - 0.003 17.4 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 Matrixin Gal_Lectin PF02140.18 CBY09547.1 - 6.2e-28 97.1 21.0 1.7e-15 57.2 2.5 3.4 3 0 0 3 3 3 2 Galactose binding lectin domain Astacin PF01400.24 CBY09550.1 - 2.6e-52 177.2 0.0 4.2e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CBY09550.1 - 0.0037 17.1 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 Matrixin Gal_Lectin PF02140.18 CBY09551.1 - 4e-28 97.7 19.8 1.7e-15 57.2 2.5 3.2 3 0 0 3 3 3 2 Galactose binding lectin domain Glyco_transf_7N PF13733.6 CBY09553.1 - 1.7e-36 124.8 0.6 3.1e-36 124.0 0.6 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY09553.1 - 6.4e-26 89.8 0.7 1.5e-25 88.6 0.7 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Laminin_N PF00055.17 CBY09554.1 - 1.3e-55 188.6 5.2 1.3e-55 188.6 5.2 2.8 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CBY09554.1 - 1.1e-10 41.5 54.9 9.5e-07 28.9 13.2 4.4 4 0 0 4 4 4 3 Laminin EGF domain Glyco_transf_54 PF04666.13 CBY09554.1 - 6.2 5.6 5.9 7 5.4 0.7 2.2 2 0 0 2 2 2 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DivIC PF04977.15 CBY09556.1 - 0.017 14.9 8.7 0.35 10.7 0.6 2.7 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 CBY09556.1 - 0.025 15.2 2.6 0.025 15.2 2.6 2.8 1 1 1 3 3 3 0 Initiation control protein YabA TraI_2B PF18340.1 CBY09556.1 - 0.12 12.5 0.0 0.84 9.8 0.0 2.2 2 0 0 2 2 2 0 DNA relaxase TraI 2B/2B-like domain DUF4094 PF13334.6 CBY09556.1 - 0.21 12.0 2.9 2.3 8.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 CBY09556.1 - 0.45 11.2 6.1 7.5 7.3 0.8 3.1 3 0 0 3 3 3 0 SlyX FlaC_arch PF05377.11 CBY09556.1 - 0.59 10.6 11.7 3.1 8.3 1.7 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 CBY09556.1 - 2.5 8.5 12.4 1.6 9.2 1.7 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) LapA_dom PF06305.11 CBY09556.1 - 3.5 7.5 8.4 11 5.9 0.8 3.8 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain Lebercilin PF15619.6 CBY09556.1 - 6.4 6.4 20.8 1.6 8.3 2.9 2.8 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease XRN_M PF17846.1 CBY09557.1 - 0.083 11.8 5.3 0.11 11.4 5.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF4407 PF14362.6 CBY09557.1 - 0.23 10.8 2.3 0.26 10.6 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 CBY09557.1 - 0.87 8.4 1.8 0.91 8.4 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4460 PF14687.6 CBY09557.1 - 0.92 9.6 5.7 7.5 6.7 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) LapA_dom PF06305.11 CBY09557.1 - 1 9.2 4.6 13 5.7 3.7 2.9 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain 60KD_IMP PF02096.20 CBY09557.1 - 4.1 7.3 6.4 7.1 6.5 6.4 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Phospholip_A2_1 PF00068.19 CBY09558.1 - 1.9e-19 70.2 6.1 1.9e-19 70.2 6.1 2.1 2 0 0 2 2 2 1 Phospholipase A2 CBM_14 PF01607.24 CBY09559.1 - 1.7e-15 56.9 4.7 2.5e-15 56.4 4.7 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain SSP160 PF06933.11 CBY09559.1 - 0.021 13.0 5.5 0.027 12.7 5.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 CBY09559.1 - 0.047 11.7 4.8 0.055 11.5 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.11 CBY09559.1 - 0.053 13.5 2.4 0.065 13.2 2.4 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF3439 PF11921.8 CBY09559.1 - 7.7 6.5 15.9 13 5.8 15.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Galactosyl_T PF01762.21 CBY09560.1 - 2e-19 70.2 2.3 3.8e-18 66.0 2.3 2.3 1 1 0 1 1 1 1 Galactosyltransferase Zona_pellucida PF00100.23 CBY09561.1 - 2.1e-21 76.9 1.3 3.6e-21 76.1 1.3 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Trypsin PF00089.26 CBY09562.1 - 1.8e-06 28.0 0.1 5.8e-06 26.3 0.1 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY09562.1 - 0.0022 18.9 0.0 0.0039 18.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY09562.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 TPR_2 PF07719.17 CBY09563.1 - 7.5e-35 116.2 36.2 2.9e-05 23.8 1.7 16.2 16 1 0 16 16 16 9 Tetratricopeptide repeat TPR_19 PF14559.6 CBY09563.1 - 2.1e-34 117.8 8.7 0.0006 20.3 0.0 10.7 6 2 5 12 12 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 CBY09563.1 - 4.8e-33 111.6 33.1 8.4e-05 22.2 0.0 13.5 14 1 0 14 14 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBY09563.1 - 3e-26 89.4 16.8 4.9e-05 23.2 0.5 13.7 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_14 PF13428.6 CBY09563.1 - 1e-25 88.2 7.6 0.85 10.6 0.0 14.9 10 4 6 16 16 16 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBY09563.1 - 1.9e-24 84.2 20.5 0.16 12.4 0.0 14.7 13 1 1 14 14 14 6 Tetratricopeptide repeat TPR_11 PF13414.6 CBY09563.1 - 2.9e-24 84.5 12.3 7.8e-05 22.3 0.0 11.3 9 3 2 11 11 11 5 TPR repeat TPR_12 PF13424.6 CBY09563.1 - 4.9e-22 78.0 24.3 0.0039 17.4 0.9 11.0 5 2 7 13 13 13 7 Tetratricopeptide repeat TPR_7 PF13176.6 CBY09563.1 - 9.2e-20 69.2 10.7 0.0034 17.3 0.4 11.7 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY09563.1 - 4.3e-19 68.9 7.5 0.084 13.5 0.0 10.0 7 2 3 11 11 10 5 Tetratricopeptide repeat TPR_6 PF13174.6 CBY09563.1 - 1.4e-14 53.7 25.3 0.054 14.1 0.0 13.0 16 0 0 16 16 13 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBY09563.1 - 8.5e-12 45.1 2.0 0.15 12.2 0.0 7.4 5 2 2 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY09563.1 - 1.8e-10 40.9 16.1 0.054 13.7 1.9 7.5 4 3 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 CBY09563.1 - 0.0021 18.7 9.7 0.045 14.4 1.8 3.9 4 0 0 4 4 2 2 Sel1 repeat TPR_10 PF13374.6 CBY09563.1 - 0.0024 17.7 33.7 0.67 9.9 0.9 11.8 14 0 0 14 14 14 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 CBY09563.1 - 0.0025 17.9 2.4 3.6 7.8 0.0 5.7 5 2 1 6 6 5 1 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 CBY09563.1 - 0.0044 17.5 6.5 8.8 7.3 0.0 5.7 5 0 0 5 5 4 0 Tetratricopeptide repeat IlvC PF01450.19 CBY09563.1 - 0.047 14.0 0.6 0.15 12.3 0.6 1.9 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF4810 PF16068.5 CBY09563.1 - 0.071 13.7 0.0 0.071 13.7 0.0 4.8 6 0 0 6 6 3 0 Domain of unknown function (DUF4810) TPR_21 PF09976.9 CBY09563.1 - 0.089 12.5 0.1 0.089 12.5 0.1 4.9 4 1 0 5 5 4 0 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 CBY09563.1 - 0.27 11.3 8.2 37 4.4 0.9 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat FlbT PF07378.11 CBY09563.1 - 1.3 9.1 6.3 0.25 11.4 0.1 3.0 3 0 0 3 3 3 0 Flagellar protein FlbT Fis1_TPR_C PF14853.6 CBY09563.1 - 9.8 6.3 8.2 4.4 7.5 1.1 4.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat adh_short_C2 PF13561.6 CBY09564.1 - 1.2e-47 162.4 0.2 1.5e-47 162.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY09564.1 - 1.4e-42 145.4 1.8 1.8e-42 145.0 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY09564.1 - 5.1e-11 42.8 0.2 8e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 CBY09564.1 - 0.00036 21.1 0.1 0.00085 19.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 CBY09564.1 - 0.039 14.5 0.8 0.071 13.7 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CBY09564.1 - 0.061 13.2 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 CBY09564.1 - 0.07 12.3 0.6 0.39 9.8 0.3 1.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein EXS PF03124.14 CBY09565.1 - 0.0012 18.2 3.0 0.0015 17.9 3.0 1.2 1 0 0 1 1 1 1 EXS family DUF2663 PF10864.8 CBY09565.1 - 0.0064 16.9 0.8 0.0064 16.9 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2663) COesterase PF00135.28 CBY09566.1 - 1.1e-71 242.3 0.0 1.6e-71 241.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_M14 PF00246.24 CBY09566.1 - 9.8e-36 124.0 0.1 1.6e-35 123.3 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Abhydrolase_3 PF07859.13 CBY09566.1 - 2.3e-05 24.4 0.0 0.00017 21.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CBY09566.1 - 0.023 13.6 0.0 0.062 12.1 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Methyltransf_11 PF08241.12 CBY09567.1 - 4.8e-11 43.2 0.0 9.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY09567.1 - 5e-10 40.0 0.1 1.7e-09 38.2 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY09567.1 - 2.6e-07 31.3 0.0 5.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY09567.1 - 1.7e-06 28.0 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY09567.1 - 1.9e-05 24.1 0.1 6.3e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CBY09567.1 - 3e-05 23.9 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 CBY09567.1 - 0.093 11.9 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase COesterase PF00135.28 CBY09568.1 - 2.1e-135 452.5 0.0 2.6e-135 452.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY09568.1 - 5.2e-08 33.0 0.0 2.2e-07 30.9 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold AChE_tetra PF08674.10 CBY09568.1 - 9.4e-05 22.0 3.5 0.00036 20.2 3.5 2.0 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain Peptidase_S9 PF00326.21 CBY09568.1 - 0.0034 16.9 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family TSP_1 PF00090.19 CBY09569.1 - 1.1e-05 25.6 3.8 1.1e-05 25.6 3.8 3.2 3 1 0 3 3 3 1 Thrombospondin type 1 domain Kelch_6 PF13964.6 CBY09569.1 - 2e-05 24.7 0.3 0.043 14.1 0.1 3.3 3 0 0 3 3 3 2 Kelch motif OmpH PF03938.14 CBY09569.1 - 0.008 16.5 2.6 0.43 10.9 0.1 2.2 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Kelch_5 PF13854.6 CBY09569.1 - 0.0091 16.0 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.25 CBY09569.1 - 0.039 13.5 0.0 0.41 10.3 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Endonuc_Holl PF10107.9 CBY09569.1 - 0.97 9.3 4.9 1.9 8.3 4.9 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Glyco_transf_7N PF13733.6 CBY09570.1 - 8.2e-39 132.3 0.0 1.4e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY09570.1 - 3.7e-24 84.2 0.5 7.1e-24 83.3 0.5 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Phage_fiber_C PF06820.12 CBY09571.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus Innexin PF00876.18 CBY09572.1 - 0.0031 16.9 0.2 0.0031 16.9 0.2 2.1 3 0 0 3 3 3 1 Innexin zf-H2C2_2 PF13465.6 CBY09573.1 - 2.2e-19 68.9 25.7 2.3e-06 27.7 2.1 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY09573.1 - 4.5e-17 61.5 31.8 2.3e-06 27.7 3.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY09573.1 - 3.7e-15 55.3 27.2 0.00026 21.6 1.8 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-BED PF02892.15 CBY09573.1 - 6e-07 29.4 19.2 0.00075 19.5 3.2 3.6 2 1 2 4 4 4 2 BED zinc finger zf-C2H2_jaz PF12171.8 CBY09573.1 - 4.7e-06 26.7 14.8 0.012 15.9 0.9 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CBY09573.1 - 6.7e-06 26.3 11.8 7.4e-06 26.2 3.2 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CBY09573.1 - 9.6e-06 25.5 21.7 0.012 15.6 1.3 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger Cys_rich_CPXG PF14255.6 CBY09573.1 - 0.0018 18.1 3.4 2.5 8.1 0.5 3.7 3 1 0 3 3 3 1 Cysteine-rich CPXCG Prok-RING_1 PF14446.6 CBY09573.1 - 0.0021 17.9 7.7 2.8 7.9 0.1 4.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 CBY09573.1 - 0.0023 18.0 8.9 0.31 11.2 1.6 3.5 1 1 3 4 4 4 3 Zinc ribbon domain zinc_ribbon_15 PF17032.5 CBY09573.1 - 0.0028 18.4 5.9 0.58 11.0 0.4 2.4 2 0 0 2 2 2 2 zinc-ribbon family Zf_RING PF16744.5 CBY09573.1 - 0.0049 16.9 10.5 0.59 10.3 0.2 3.7 2 1 2 4 4 3 1 KIAA1045 RING finger zf-C2H2_9 PF16293.5 CBY09573.1 - 0.014 15.2 5.0 5.4 6.9 0.2 3.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 CBY09573.1 - 0.016 15.6 20.1 0.063 13.7 2.4 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FYVE PF01363.21 CBY09573.1 - 0.045 13.9 14.7 14 5.9 14.6 3.0 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_3rep PF18868.1 CBY09573.1 - 0.052 14.2 16.5 0.13 13.0 0.5 4.0 2 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 CBY09573.1 - 0.059 13.7 19.7 4.9 7.6 2.2 4.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 CBY09573.1 - 0.096 12.3 12.9 5 6.8 0.3 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Prok-RING_4 PF14447.6 CBY09573.1 - 0.13 12.2 5.4 5.8 6.9 0.2 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 CBY09573.1 - 0.14 12.7 8.9 3.2 8.3 0.5 4.6 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain HypA PF01155.19 CBY09573.1 - 0.14 12.2 4.6 5 7.2 0.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 CBY09573.1 - 0.2 11.6 9.8 2.9 7.9 2.0 3.4 3 1 0 3 3 3 0 SprT-like zinc ribbon domain zf-AN1 PF01428.16 CBY09573.1 - 0.22 11.7 12.5 5.5 7.3 0.2 4.3 4 0 0 4 4 4 0 AN1-like Zinc finger GAGA PF09237.11 CBY09573.1 - 0.53 10.1 0.1 0.53 10.1 0.1 4.0 2 1 3 5 5 5 0 GAGA factor HNH_5 PF14279.6 CBY09573.1 - 0.56 10.1 10.6 14 5.6 0.3 4.1 3 1 0 3 3 3 0 HNH endonuclease zf-C2HC_2 PF13913.6 CBY09573.1 - 0.91 9.5 14.0 1.4 8.9 2.4 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DZR PF12773.7 CBY09573.1 - 0.93 9.6 8.2 36 4.5 8.2 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-CHY PF05495.12 CBY09573.1 - 0.94 10.0 17.4 1.4e+02 3.0 0.1 3.0 1 1 1 2 2 2 0 CHY zinc finger UBZ_FAAP20 PF15750.5 CBY09573.1 - 1.3 9.1 7.3 13 5.9 0.3 3.5 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-MYST PF17772.1 CBY09573.1 - 1.3 8.7 7.6 2.6 7.7 0.3 3.3 3 0 0 3 3 3 0 MYST family zinc finger domain FYDLN_acid PF09538.10 CBY09573.1 - 1.4 9.6 5.9 28 5.5 0.5 3.9 2 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf_ZIC PF18366.1 CBY09573.1 - 4.1 7.6 9.9 1.4 9.0 0.3 3.2 1 1 2 3 3 3 0 Zic proteins zinc finger domain Lar_restr_allev PF14354.6 CBY09573.1 - 6.5 7.2 10.4 14 6.1 7.9 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-CHCC PF10276.9 CBY09573.1 - 9.8 6.3 11.5 3.7 7.7 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger domain Piwi PF02171.17 CBY09574.1 - 0.0013 18.1 0.1 0.017 14.4 0.0 1.9 2 0 0 2 2 2 2 Piwi domain Aldo_ket_red PF00248.21 CBY09575.1 - 7e-48 163.3 0.0 8.8e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Utp13 PF08625.11 CBY09575.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain EGF_CA PF07645.15 CBY09576.1 - 8e-54 179.6 136.4 6.9e-11 42.2 13.1 8.9 8 1 0 8 8 8 7 Calcium-binding EGF domain EGF_3 PF12947.7 CBY09576.1 - 5.7e-46 154.4 158.5 3.2e-09 36.8 17.1 9.0 8 1 1 9 9 9 7 EGF domain EGF PF00008.27 CBY09576.1 - 3.9e-24 84.6 123.0 2.9e-05 24.3 10.9 8.8 8 0 0 8 8 8 7 EGF-like domain hEGF PF12661.7 CBY09576.1 - 7.8e-13 48.5 105.1 0.00015 22.3 5.8 10.1 10 0 0 10 10 10 7 Human growth factor-like EGF cEGF PF12662.7 CBY09576.1 - 3.5e-12 46.0 88.7 0.00025 20.9 5.0 9.5 9 1 0 9 9 9 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY09576.1 - 0.002 18.3 129.7 0.0034 17.6 10.0 8.8 7 2 1 8 8 8 5 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY09576.1 - 0.0026 17.8 29.5 0.0035 17.4 10.5 7.8 7 0 0 7 7 7 4 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY09576.1 - 0.27 11.5 105.0 0.16 12.3 11.4 8.8 7 1 1 8 8 8 0 Pvs28 EGF domain RVT_1 PF00078.27 CBY09578.1 - 9.4e-16 58.0 0.3 1.9e-15 57.0 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CBY09578.1 - 7.5e-06 26.4 0.0 3e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CBY09578.1 - 0.0034 17.7 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CBY09578.1 - 0.027 15.1 0.0 0.072 13.7 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease HTH_33 PF13592.6 CBY09578.1 - 0.062 12.9 0.4 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 Winged helix-turn helix RT_RNaseH PF17917.1 CBY09579.1 - 2.6e-27 95.2 0.1 5.4e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY09579.1 - 3.2e-24 84.9 0.0 6.3e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY09579.1 - 9e-21 74.3 0.0 2.5e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY09579.1 - 4.5e-14 52.3 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CBY09579.1 - 0.0095 15.7 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CBY09580.1 - 1.3e-17 64.1 0.4 2.4e-17 63.2 0.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CBY09580.1 - 4.7e-06 27.1 0.0 2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CBY09580.1 - 0.0022 18.3 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CBY09580.1 - 0.018 15.6 0.0 0.048 14.3 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease HTH_33 PF13592.6 CBY09580.1 - 0.044 13.4 0.4 0.099 12.3 0.4 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Asp_protease PF09668.10 CBY09580.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 CBY09581.1 - 2.6e-27 95.1 0.1 5.5e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY09581.1 - 3.2e-24 84.8 0.0 6.4e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY09581.1 - 9.3e-21 74.2 0.0 2.6e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY09581.1 - 4.6e-14 52.3 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CBY09581.1 - 0.0097 15.7 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Peptidase_S49_N PF08496.10 CBY09582.1 - 0.031 14.4 7.4 0.034 14.2 7.4 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal COX16 PF14138.6 CBY09582.1 - 0.56 10.8 7.4 0.36 11.4 5.9 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF2681 PF10883.8 CBY09582.1 - 0.63 10.5 10.8 4.8 7.7 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Na_sulph_symp PF00939.19 CBY09583.1 - 1.6e-87 294.5 15.0 2e-87 294.2 15.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY09583.1 - 7.3e-33 114.0 26.6 1.3e-16 60.7 4.6 3.1 2 1 1 3 3 3 3 Citrate transporter ECSCR PF15820.5 CBY09583.1 - 0.045 13.6 1.8 0.086 12.7 0.2 2.3 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator ETRAMP PF09716.10 CBY09583.1 - 0.17 12.0 0.1 0.17 12.0 0.1 3.0 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) TauD PF02668.16 CBY09584.1 - 5.3e-26 92.0 0.9 3.1e-25 89.5 0.9 1.9 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CBY09584.1 - 1.9e-05 25.2 0.1 8.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF971) IGFBP PF00219.18 CBY09585.1 - 5.6e-07 30.1 21.2 5.6e-07 30.1 21.2 6.2 4 4 1 5 5 5 1 Insulin-like growth factor binding protein TSP_1 PF00090.19 CBY09585.1 - 0.0033 17.6 10.8 0.0033 17.6 10.8 5.9 8 1 1 9 9 9 1 Thrombospondin type 1 domain PAP2_C PF14360.6 CBY09586.1 - 4.8e-16 59.1 5.7 4.8e-16 59.1 5.7 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 CBY09586.1 - 1.6e-05 24.7 1.0 2.7e-05 23.9 1.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 CBY09586.1 - 0.00082 19.1 0.4 0.00082 19.1 0.4 2.4 2 1 0 2 2 2 1 PAP2 superfamily CUB PF00431.20 CBY09587.1 - 4.3e-09 36.7 0.4 0.001 19.4 0.1 2.3 2 0 0 2 2 2 2 CUB domain GATA PF00320.27 CBY09588.1 - 2.1e-28 97.6 15.1 1.5e-15 56.5 4.0 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CBY09588.1 - 0.00036 20.0 7.0 0.024 14.1 0.7 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 CBY09588.1 - 0.0024 17.9 2.2 1.4 9.1 0.4 2.5 2 0 0 2 2 2 2 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 CBY09588.1 - 0.01 15.7 8.6 0.13 12.2 2.1 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 CBY09588.1 - 0.011 15.9 5.3 0.34 11.1 0.3 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 CBY09588.1 - 0.86 9.7 10.9 18 5.4 2.6 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 CBY09588.1 - 1.3 9.0 4.9 8.7 6.3 0.8 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2387 PF09526.10 CBY09588.1 - 1.9 8.7 10.5 0.13 12.4 0.9 3.0 2 1 2 4 4 4 0 Probable metal-binding protein (DUF2387) FYVE PF01363.21 CBY09588.1 - 3.9 7.7 9.5 85 3.4 9.5 2.4 1 1 0 1 1 1 0 FYVE zinc finger ADK_lid PF05191.14 CBY09588.1 - 5.8 7.0 11.2 5.8 7.0 1.8 4.2 4 0 0 4 4 4 0 Adenylate kinase, active site lid CUB PF00431.20 CBY09593.1 - 2.5e-08 34.2 0.2 3.6e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 CUB domain EGF PF00008.27 CBY09594.1 - 1.9e-103 338.1 624.5 4.4e-06 26.9 3.3 45.4 44 1 0 44 44 44 40 EGF-like domain hEGF PF12661.7 CBY09594.1 - 1e-13 51.3 501.7 0.0011 19.5 1.4 45.9 46 1 0 46 46 46 29 Human growth factor-like EGF EGF_2 PF07974.13 CBY09594.1 - 8.8e-08 32.4 710.3 0.0024 18.2 5.4 45.0 42 2 2 44 44 44 29 EGF-like domain Late_protein_L2 PF00513.18 CBY09594.1 - 0.6 9.1 2.1 0.99 8.3 2.1 1.2 1 0 0 1 1 1 0 Late Protein L2 Zona_pellucida PF00100.23 CBY09595.1 - 2.3e-20 73.5 0.0 2.7e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain KSHV_K8 PF07188.11 CBY09595.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein AAA_21 PF13304.6 CBY09596.1 - 0.9 9.3 6.4 1.1 9.0 6.4 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system BTB PF00651.31 CBY09597.1 - 8.9e-28 96.7 0.9 2.4e-27 95.4 0.9 1.8 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY09597.1 - 2.4e-27 95.0 0.9 4.2e-27 94.2 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 CBY09597.1 - 2.2e-15 55.9 3.2 6.7e-05 22.4 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 CBY09597.1 - 4.7e-09 36.2 5.9 0.004 17.4 0.0 4.3 2 1 2 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY09597.1 - 1.5e-05 24.8 0.3 0.036 14.1 0.2 3.1 2 0 0 2 2 2 2 Kelch motif DUF3342 PF11822.8 CBY09597.1 - 0.00058 20.0 0.5 0.0074 16.5 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_4 PF13418.6 CBY09597.1 - 0.2 11.7 4.3 36 4.5 0.1 4.1 3 1 1 4 4 4 0 Galactose oxidase, central domain DAO PF01266.24 CBY09598.1 - 3.4e-10 40.1 0.0 1.1e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBY09598.1 - 9.7e-07 28.3 0.0 5.3e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY09598.1 - 1.4e-06 28.5 0.4 6.2e-06 26.3 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBY09598.1 - 0.00018 20.7 0.2 0.00033 19.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CBY09598.1 - 0.00023 20.3 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBY09598.1 - 0.00027 19.8 0.5 0.012 14.4 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CBY09598.1 - 0.00037 19.8 0.0 0.0038 16.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 CBY09598.1 - 0.003 17.0 0.3 0.0063 15.9 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CBY09598.1 - 0.0066 16.4 0.4 0.26 11.2 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 CBY09598.1 - 0.0098 15.9 0.9 0.28 11.2 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CBY09598.1 - 0.021 15.4 0.0 0.056 14.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY09598.1 - 0.051 12.8 0.1 0.089 12.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 CBY09598.1 - 0.055 12.7 0.9 1.6 7.9 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 CBY09598.1 - 0.13 12.4 0.2 0.29 11.3 0.0 1.7 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CarbopepD_reg_2 PF13715.6 CBY09598.1 - 0.14 12.1 0.0 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 CarboxypepD_reg-like domain NAD_Gly3P_dh_N PF01210.23 CBY09598.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Phage_integrase PF00589.22 CBY09599.1 - 1.5e-10 41.1 0.0 3.5e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Phage integrase family RR_TM4-6 PF06459.12 CBY09599.1 - 0.44 10.3 7.7 4.2 7.1 4.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RVT_1 PF00078.27 CBY09600.1 - 1.3e-10 41.2 0.0 2.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 CBY09600.1 - 0.028 14.0 0.3 0.086 12.4 0.0 1.9 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) DAO PF01266.24 CBY09603.1 - 4.5e-10 39.7 0.0 1.4e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBY09603.1 - 9.8e-07 28.3 0.0 5.3e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY09603.1 - 1.4e-06 28.5 0.4 6.2e-06 26.3 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBY09603.1 - 0.00018 20.7 0.2 0.00033 19.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CBY09603.1 - 0.00024 20.3 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBY09603.1 - 0.00028 19.7 0.5 0.012 14.4 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CBY09603.1 - 0.00037 19.8 0.0 0.0038 16.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 CBY09603.1 - 0.0031 16.9 0.3 0.0063 15.9 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CBY09603.1 - 0.0067 16.3 0.4 0.26 11.2 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 CBY09603.1 - 0.0098 15.9 0.9 0.28 11.2 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CBY09603.1 - 0.021 15.4 0.0 0.056 14.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY09603.1 - 0.051 12.8 0.1 0.089 12.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 CBY09603.1 - 0.06 12.6 0.9 1.6 7.9 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 CBY09603.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CarbopepD_reg_2 PF13715.6 CBY09603.1 - 0.14 12.1 0.0 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 CarboxypepD_reg-like domain NAD_Gly3P_dh_N PF01210.23 CBY09603.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Syntaxin-6_N PF09177.11 CBY09607.1 - 0.026 15.0 1.0 0.62 10.7 0.0 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal UDPG_MGDP_dh_C PF03720.15 CBY09607.1 - 0.028 14.8 0.1 4.6 7.7 0.1 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DNA_topoisoIV PF00521.20 CBY09607.1 - 0.075 11.9 1.2 2.1 7.2 0.0 2.1 1 1 1 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A DLH PF01738.18 CBY09607.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family LXG PF04740.12 CBY09607.1 - 0.14 11.8 0.1 5.2 6.7 0.0 2.3 1 1 1 2 2 2 0 LXG domain of WXG superfamily CorA PF01544.18 CBY09607.1 - 0.43 9.8 3.7 2.9 7.1 0.9 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Herpes_capsid PF06112.11 CBY09608.1 - 0.18 11.9 3.7 0.23 11.5 3.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AP3D1 PF06375.11 CBY09609.1 - 0.25 11.6 6.6 0.3 11.3 6.6 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 RT_RNaseH_2 PF17919.1 CBY09613.1 - 3.1e-29 101.0 0.0 5.8e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY09613.1 - 1.4e-22 79.9 0.0 2.3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_min_cap2 PF06152.11 CBY09614.1 - 0.12 11.2 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 RT_RNaseH_2 PF17919.1 CBY09617.1 - 1.3e-27 95.8 0.1 2e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY09617.1 - 7.8e-17 61.5 0.0 1.1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 CBY09617.1 - 0.051 13.4 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase thumb domain DUF3873 PF12989.7 CBY09618.1 - 0.13 12.7 1.1 1.2 9.5 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) rve PF00665.26 CBY09619.1 - 9.4e-09 35.5 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY09619.1 - 2e-07 31.0 0.0 2e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CBY09619.1 - 0.00012 22.0 0.1 0.00038 20.5 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_pol_viral_C PF00336.18 CBY09619.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain zf-H3C2 PF16721.5 CBY09619.1 - 0.15 12.5 0.5 0.37 11.2 0.2 1.8 1 1 1 2 2 2 0 Zinc-finger like, probable DNA-binding zf-H2C2 PF09337.10 CBY09619.1 - 0.21 11.8 0.3 0.21 11.8 0.3 2.0 2 0 0 2 2 2 0 H2C2 zinc finger Torus PF16131.5 CBY09620.1 - 3e-05 24.7 0.3 0.00014 22.6 0.3 2.1 1 0 0 1 1 1 1 Torus domain PDDEXK_5 PF11645.8 CBY09620.1 - 0.083 12.9 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 PD-(D/E)XK endonuclease Ly49 PF08391.10 CBY09620.1 - 0.11 12.9 2.1 0.3 11.5 0.1 2.1 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF445 PF04286.12 CBY09620.1 - 0.13 12.0 1.2 1.8 8.3 1.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF445) RT_RNaseH PF17917.1 CBY09621.1 - 1.4e-27 96.1 0.0 2.3e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY09621.1 - 6.4e-22 77.5 0.0 1.1e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY09621.1 - 2e-15 57.0 0.0 5.6e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY09621.1 - 1.9e-13 50.3 0.0 4.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain AAA_25 PF13481.6 CBY09621.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MULE PF10551.9 CBY09622.1 - 0.002 18.5 0.1 0.0063 16.9 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain Thioredoxin_8 PF13905.6 CBY09623.1 - 0.016 15.5 0.1 0.027 14.8 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like RT_RNaseH PF17917.1 CBY09626.1 - 5.2e-30 103.8 0.1 1.6e-29 102.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY09626.1 - 2.5e-27 94.8 0.0 4.6e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY09626.1 - 2.2e-18 66.6 0.1 4.6e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 CBY09626.1 - 0.032 14.1 1.0 0.4 10.5 0.2 2.8 2 1 0 2 2 2 0 Reverse transcriptase thumb domain Coiled-coil_56 PF09813.9 CBY09627.1 - 0.12 12.5 0.5 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 WW_1 PF18507.1 CBY09627.1 - 0.27 10.9 2.7 0.25 11.1 0.2 2.2 2 0 0 2 2 2 0 WW domain RT_RNaseH_2 PF17919.1 CBY09628.1 - 4.4e-11 42.7 0.3 4.4e-10 39.5 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY09628.1 - 2.9e-08 34.0 0.1 1.9e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY09628.1 - 8.2e-08 32.0 0.2 2.6e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CBY09628.1 - 0.0012 19.4 1.0 0.0032 18.0 0.1 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CBY09628.1 - 0.0047 17.5 0.2 0.019 15.6 0.2 2.0 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 CBY09628.1 - 0.0063 16.6 0.5 0.031 14.4 0.0 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain DUF4041 PF13250.6 CBY09628.1 - 0.045 13.6 0.9 1.1 9.2 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) DUF515 PF04415.12 CBY09629.1 - 1.7 7.0 5.7 2.2 6.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Gal-3-0_sulfotr PF06990.11 CBY09630.1 - 9e-23 80.8 6.2 5.1e-18 65.1 0.4 2.4 1 1 0 2 2 2 2 Galactose-3-O-sulfotransferase HnRNPA1 PF11627.8 CBY09630.1 - 0.0067 16.6 1.9 0.0078 16.4 0.5 1.9 2 0 0 2 2 2 1 Nuclear factor hnRNPA1 Myosin_head PF00063.21 CBY09631.1 - 1.6e-230 766.9 7.8 2.6e-230 766.3 7.8 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 CBY09631.1 - 6.9e-59 197.0 0.1 4e-30 104.5 0.0 3.1 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 CBY09631.1 - 3.4e-27 95.2 0.0 8.3e-17 61.7 0.0 4.0 3 0 0 3 3 3 2 FERM central domain FERM_N PF09379.10 CBY09631.1 - 2.2e-10 40.3 0.8 0.0002 21.2 0.1 2.7 2 0 0 2 2 2 2 FERM N-terminal domain IQ PF00612.27 CBY09631.1 - 2.9e-08 32.8 34.7 0.00032 20.2 5.1 6.0 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY09631.1 - 8.4e-05 22.9 0.0 0.0042 17.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY09631.1 - 0.003 18.0 0.0 0.015 15.7 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CBY09631.1 - 0.0087 16.6 0.0 0.034 14.7 0.0 2.0 1 0 0 1 1 1 1 ABC transporter PID PF00640.23 CBY09631.1 - 0.015 15.3 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Pkinase PF00069.25 CBY09632.1 - 1.2e-34 119.9 0.0 1.7e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09632.1 - 2.9e-28 98.9 0.0 4.3e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY09632.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY09632.1 - 0.076 12.3 0.0 0.28 10.5 0.0 1.7 1 1 1 2 2 2 0 Kinase-like MFS_1 PF07690.16 CBY09634.1 - 3.5e-18 65.6 14.8 5.2e-09 35.5 6.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 CBY09635.1 - 3.2e-17 62.6 3.1 0.00022 22.0 0.1 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09635.1 - 1.7e-11 44.2 0.4 0.0056 16.9 0.1 5.1 3 3 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY09635.1 - 1.3e-07 31.2 0.0 0.00053 19.4 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CBY09635.1 - 7.7e-05 21.5 0.3 1.4 7.5 0.0 4.1 5 0 0 5 5 5 2 Nucleoporin Nup120/160 IKI3 PF04762.12 CBY09635.1 - 0.0015 16.7 0.0 0.0022 16.1 0.0 1.4 1 0 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.5 CBY09635.1 - 0.042 12.8 0.0 19 4.0 0.0 3.9 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBY09635.1 - 0.05 13.2 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 PQQ-like domain Utp8 PF10395.9 CBY09635.1 - 0.26 9.7 0.1 1.2 7.6 0.0 1.8 1 1 1 2 2 2 0 Utp8 family zf-RING_UBOX PF13445.6 CBY09636.1 - 4.1e-07 29.9 2.7 4.1e-07 29.9 2.7 2.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 CBY09636.1 - 1.1e-06 28.2 5.1 3.1e-06 26.8 5.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CBY09636.1 - 1.6e-06 28.3 10.7 4.7e-06 26.8 10.7 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY09636.1 - 1.1e-05 25.1 5.6 4.5e-05 23.2 5.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY09636.1 - 0.00095 19.0 3.0 0.00095 19.0 3.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CBY09636.1 - 0.068 13.0 3.3 0.14 12.0 3.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CBY09636.1 - 0.14 12.4 7.9 0.08 13.1 2.9 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CBY09636.1 - 0.27 11.2 8.9 1.5 8.8 8.9 2.3 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 CBY09636.1 - 6.7 7.0 7.5 34 4.7 5.9 2.9 2 1 1 3 3 3 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CBY09636.1 - 8.2 6.1 7.4 0.97 9.1 2.7 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Sec7 PF01369.20 CBY09637.1 - 3.5e-67 225.6 0.1 1.7e-66 223.4 0.0 2.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 CBY09637.1 - 1e-47 162.0 0.7 1e-47 162.0 0.7 4.5 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CBY09637.1 - 1.2e-31 108.4 4.2 1.3e-29 101.9 0.0 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 CBY09637.1 - 8.4e-25 87.5 3.5 8.4e-25 87.5 3.5 3.4 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 TPR_1 PF00515.28 CBY09638.1 - 4.4e-46 152.9 38.1 1.3e-06 28.0 0.3 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 CBY09638.1 - 3.9e-39 129.6 32.2 9.2e-06 25.4 0.1 10.0 10 1 1 11 11 9 8 Tetratricopeptide repeat STI1 PF17830.1 CBY09638.1 - 1e-38 131.1 22.1 2.4e-20 72.2 4.2 2.6 2 0 0 2 2 2 2 STI1 domain TPR_11 PF13414.6 CBY09638.1 - 1.2e-30 104.9 18.9 2e-07 30.6 0.1 7.5 5 1 2 7 7 7 6 TPR repeat TPR_8 PF13181.6 CBY09638.1 - 1.1e-19 68.9 33.1 9.8e-05 22.3 0.1 9.7 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 CBY09638.1 - 1.6e-18 66.7 10.6 8.5e-07 29.2 0.1 7.7 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBY09638.1 - 8.9e-17 61.5 0.4 0.0059 17.2 0.0 6.5 5 2 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBY09638.1 - 2.2e-13 49.8 5.3 1.8 9.6 0.2 8.1 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBY09638.1 - 1.3e-10 40.9 13.0 0.076 13.4 0.1 7.4 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBY09638.1 - 1.5e-08 34.0 8.0 2.3 8.4 0.0 8.1 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY09638.1 - 7e-08 32.9 15.4 0.8 10.3 0.0 7.5 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY09638.1 - 0.0002 21.8 14.3 14 6.6 0.0 8.4 9 1 0 9 9 8 0 Tetratricopeptide repeat MIT PF04212.18 CBY09638.1 - 0.00039 20.4 17.9 1.9 8.6 0.4 6.6 6 1 1 7 7 6 2 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 CBY09638.1 - 0.0005 19.5 4.4 7.1 6.2 0.0 5.2 5 0 0 5 5 5 1 SHNi-TPR TPR_10 PF13374.6 CBY09638.1 - 0.0055 16.5 11.1 10 6.2 0.1 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY09638.1 - 0.0065 16.5 10.9 11 6.2 0.2 6.4 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CBY09638.1 - 0.018 15.2 0.1 18 5.6 0.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 CBY09638.1 - 0.1 12.3 18.9 1.4 8.6 0.5 4.8 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 CBY09638.1 - 0.17 12.1 13.2 0.49 10.6 0.5 4.7 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TCTP PF00838.17 CBY09638.1 - 2 8.7 11.2 0.47 10.8 4.7 2.8 1 1 1 2 2 2 0 Translationally controlled tumour protein F-box-like PF12937.7 CBY09641.1 - 0.0002 21.2 0.0 0.00035 20.4 0.0 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 CBY09641.1 - 0.00078 19.3 0.0 0.0019 18.1 0.0 1.6 2 0 0 2 2 2 1 F-box domain Connexin PF00029.19 CBY09642.1 - 3.8e-58 197.0 8.3 6.1e-58 196.3 8.3 1.3 1 1 0 1 1 1 1 Connexin Tho2 PF11262.8 CBY09642.1 - 0.007 15.6 0.7 0.058 12.6 0.2 2.1 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 AAA_17 PF13207.6 CBY09642.1 - 0.094 13.1 3.6 0.14 12.6 3.6 1.2 1 0 0 1 1 1 0 AAA domain RNase_H PF00075.24 CBY09643.1 - 2.2e-21 76.5 0.0 2.9e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CBY09643.1 - 3.2e-09 36.6 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like ADP_PFK_GK PF04587.15 CBY09643.1 - 0.0079 14.8 0.0 0.0094 14.6 0.0 1.1 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Trypsin PF00089.26 CBY09644.1 - 3.9e-29 102.0 2.8 5.3e-29 101.6 2.8 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY09644.1 - 0.024 15.0 0.1 0.039 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Phospholip_A2_1 PF00068.19 CBY09645.1 - 1.8e-13 50.9 7.0 1.8e-13 50.9 7.0 1.9 1 1 1 2 2 2 1 Phospholipase A2 MIP PF00230.20 CBY09646.1 - 1.8e-13 50.7 1.4 2e-13 50.6 1.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_9 PF00759.19 CBY09647.1 - 1.2e-130 436.7 13.9 1.8e-130 436.1 13.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_4_9 PF02018.17 CBY09647.1 - 1.4e-13 51.3 0.6 4.3e-13 49.7 0.6 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain DPBB_1 PF03330.18 CBY09647.1 - 6.7e-08 32.7 0.1 2.3e-07 31.0 0.1 1.9 1 0 0 1 1 1 1 Lytic transglycolase TPR_12 PF13424.6 CBY09647.1 - 0.33 11.3 1.4 12 6.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4542 PF15075.6 CBY09648.1 - 0.00013 22.3 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) zf-RING_2 PF13639.6 CBY09649.1 - 7.5e-13 48.6 6.3 1.2e-12 47.9 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY09649.1 - 3.7e-10 39.5 6.7 5.8e-10 38.8 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY09649.1 - 5.5e-08 32.7 3.0 8.4e-08 32.1 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY09649.1 - 1.2e-07 31.5 5.0 2.1e-07 30.7 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY09649.1 - 1.4e-07 31.1 1.7 3.2e-07 30.0 1.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBY09649.1 - 6.5e-07 29.3 2.9 1.2e-06 28.4 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY09649.1 - 9.3e-07 29.0 6.9 2.2e-06 27.8 6.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY09649.1 - 3.8e-06 26.6 2.9 5.6e-06 26.1 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBY09649.1 - 3.9e-05 23.2 2.6 7.1e-05 22.4 2.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBY09649.1 - 0.0011 18.8 8.2 0.024 14.5 8.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 CBY09649.1 - 0.025 14.6 2.3 0.025 14.6 2.3 2.2 2 1 0 2 2 2 0 Zinc-finger zf-ANAPC11 PF12861.7 CBY09649.1 - 0.031 14.3 1.3 0.065 13.3 1.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CBY09649.1 - 0.073 13.2 3.0 0.16 12.1 3.0 1.6 1 1 0 1 1 1 0 RING-variant domain Vps39_2 PF10367.9 CBY09649.1 - 0.11 12.9 0.3 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING-like PF08746.11 CBY09649.1 - 0.22 11.8 5.0 0.69 10.3 5.1 1.8 1 1 1 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.6 CBY09649.1 - 0.24 11.6 2.9 0.61 10.3 2.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CBY09649.1 - 0.36 10.7 6.5 0.82 9.5 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CBY09649.1 - 0.64 10.2 5.4 3.9 7.7 5.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Ribosomal_S4 PF00163.19 CBY09650.1 - 0.04 14.8 0.5 0.059 14.3 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Sema PF01403.19 CBY09652.1 - 1.5e-21 76.7 1.0 1.5e-21 76.7 1.0 1.9 2 0 0 2 2 2 1 Sema domain Baculo_PEP_C PF04513.12 CBY09652.1 - 0.02 14.9 0.6 0.88 9.6 0.0 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 CBY09652.1 - 0.031 14.6 6.9 3.3 8.1 0.7 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1351 PF07083.11 CBY09652.1 - 0.055 13.2 10.1 3.7 7.3 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1351) DASH_Dam1 PF08653.10 CBY09652.1 - 0.32 10.8 2.7 26 4.7 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 HrpB7 PF09486.10 CBY09652.1 - 0.54 10.6 8.1 3 8.2 0.3 3.0 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF724 PF05266.14 CBY09652.1 - 0.76 9.6 10.1 0.058 13.2 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YabA PF06156.13 CBY09652.1 - 1.1 9.9 11.5 11 6.7 1.9 3.5 2 1 1 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 CBY09652.1 - 1.4 9.1 13.0 0.19 11.9 4.4 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 CBY09652.1 - 1.5 9.4 9.0 8.3 7.0 0.5 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.11 CBY09652.1 - 1.6 9.3 5.6 53 4.5 0.1 3.8 4 0 0 4 4 4 0 MerR, DNA binding SlyX PF04102.12 CBY09652.1 - 1.7 9.3 6.9 43 4.8 0.0 3.6 3 1 0 3 3 3 0 SlyX Prominin PF05478.11 CBY09652.1 - 2 6.3 8.4 0.65 7.9 3.6 1.9 1 1 1 2 2 2 0 Prominin DUF948 PF06103.11 CBY09652.1 - 2.2 8.6 6.0 19 5.6 0.4 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) STAT_alpha PF01017.20 CBY09652.1 - 2.3 8.1 11.2 0.26 11.2 5.9 2.0 2 0 0 2 2 2 0 STAT protein, all-alpha domain DHR10 PF18595.1 CBY09652.1 - 2.4 8.2 16.0 3.4 7.7 2.0 3.5 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain Ax_dynein_light PF10211.9 CBY09652.1 - 4.5 7.2 12.6 2.9 7.8 3.2 3.3 2 1 1 3 3 3 0 Axonemal dynein light chain Osmo_CC PF08946.10 CBY09652.1 - 6.3 7.1 7.9 6 7.2 0.3 3.4 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Nsp1_C PF05064.13 CBY09652.1 - 7.1 6.5 7.9 7.2 6.4 0.8 2.8 3 1 0 3 3 2 0 Nsp1-like C-terminal region ZapB PF06005.12 CBY09652.1 - 8.6 6.9 8.8 45 4.6 0.3 3.7 3 1 0 3 3 3 0 Cell division protein ZapB Snapin_Pallidin PF14712.6 CBY09652.1 - 8.9 6.8 10.6 19 5.7 0.1 3.4 3 1 1 4 4 3 0 Snapin/Pallidin EGF_3 PF12947.7 CBY09653.1 - 7.2e-14 51.7 37.1 1.9e-08 34.4 15.5 3.9 4 1 1 5 5 5 2 EGF domain EGF_CA PF07645.15 CBY09653.1 - 5.1e-10 39.4 14.2 5.1e-10 39.4 14.2 4.0 4 0 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.7 CBY09653.1 - 3.5e-07 30.0 5.5 3.5e-07 30.0 5.5 4.0 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.27 CBY09653.1 - 0.0003 21.0 27.4 0.00045 20.5 10.7 3.4 3 1 0 3 3 3 2 EGF-like domain hEGF PF12661.7 CBY09653.1 - 0.0021 18.6 5.3 0.0021 18.6 5.3 3.7 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY09653.1 - 0.0044 17.1 27.8 0.005 16.9 8.9 3.7 4 0 0 4 4 4 2 MSP1 EGF domain 1 Sema PF01403.19 CBY09654.1 - 4.7e-10 38.9 0.3 1.9e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Sema domain BLOC1_2 PF10046.9 CBY09654.1 - 0.0086 16.4 7.0 2 8.8 0.7 3.4 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1351 PF07083.11 CBY09654.1 - 0.019 14.7 10.5 2.3 7.9 0.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) Baculo_PEP_C PF04513.12 CBY09654.1 - 0.024 14.7 2.7 0.67 10.0 0.3 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 CBY09654.1 - 0.13 12.1 3.0 17 5.3 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 MerR-DNA-bind PF09278.11 CBY09654.1 - 0.22 12.1 4.9 33 5.1 0.0 4.0 4 0 0 4 4 4 0 MerR, DNA binding DUF1664 PF07889.12 CBY09654.1 - 0.26 11.3 9.0 4.7 7.3 0.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 CBY09654.1 - 0.31 11.7 11.5 6.2 7.5 1.6 3.4 2 1 1 3 3 3 0 Initiation control protein YabA DUF724 PF05266.14 CBY09654.1 - 0.34 10.7 10.4 0.035 13.9 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Sec34 PF04136.15 CBY09654.1 - 0.37 10.7 2.9 0.92 9.4 0.8 2.6 2 1 1 3 3 3 0 Sec34-like family HrpB7 PF09486.10 CBY09654.1 - 0.39 11.1 9.4 2.1 8.7 0.5 3.0 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 CBY09654.1 - 0.5 11.0 7.2 27 5.5 0.0 3.8 3 1 0 3 3 3 0 SlyX DHR10 PF18595.1 CBY09654.1 - 0.61 10.2 16.1 2.1 8.4 2.0 3.6 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain STAT_alpha PF01017.20 CBY09654.1 - 0.66 9.8 10.7 0.15 12.0 5.9 2.0 2 0 0 2 2 2 0 STAT protein, all-alpha domain Fib_alpha PF08702.10 CBY09654.1 - 0.75 10.0 13.6 0.12 12.6 4.5 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 CBY09654.1 - 0.84 7.5 8.6 0.32 8.9 3.5 2.0 1 1 1 2 2 2 0 Prominin NPV_P10 PF05531.12 CBY09654.1 - 0.86 10.1 10.2 6.1 7.4 0.7 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 CBY09654.1 - 1 9.7 6.5 12 6.2 0.4 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Ax_dynein_light PF10211.9 CBY09654.1 - 1.7 8.5 13.2 1.9 8.4 3.3 3.3 2 1 1 3 3 3 0 Axonemal dynein light chain Osmo_CC PF08946.10 CBY09654.1 - 1.9 8.8 7.9 3.9 7.8 0.3 3.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Snapin_Pallidin PF14712.6 CBY09654.1 - 2.6 8.5 10.8 12 6.4 0.1 3.5 3 1 1 4 4 4 0 Snapin/Pallidin Prefoldin PF02996.17 CBY09654.1 - 2.9 7.9 12.7 33 4.4 0.2 4.2 3 1 1 4 4 4 0 Prefoldin subunit ZapB PF06005.12 CBY09654.1 - 3.3 8.2 9.4 28 5.2 0.3 3.8 3 1 0 3 3 3 0 Cell division protein ZapB P4Ha_N PF08336.11 CBY09654.1 - 3.6 7.6 6.6 7.6 6.5 0.4 3.3 1 1 2 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Nsp1_C PF05064.13 CBY09654.1 - 4.2 7.2 8.7 4.4 7.1 0.8 2.9 3 1 0 3 3 2 0 Nsp1-like C-terminal region XhlA PF10779.9 CBY09654.1 - 5.5 7.3 12.0 8.2 6.7 0.2 4.2 4 0 0 4 4 4 0 Haemolysin XhlA DUF2089 PF09862.9 CBY09654.1 - 7.4 6.7 6.2 23 5.1 0.0 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF2089) CdvA PF18822.1 CBY09654.1 - 7.4 6.4 12.6 2.1 8.2 0.1 3.9 4 0 0 4 4 4 0 CdvA-like coiled-coil domain EGF_3 PF12947.7 CBY09655.1 - 1.1e-17 63.9 71.7 3.2e-08 33.6 15.5 4.8 5 1 1 6 6 6 3 EGF domain EGF_CA PF07645.15 CBY09655.1 - 9.2e-10 38.6 14.2 9.2e-10 38.6 14.2 4.8 5 0 0 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.7 CBY09655.1 - 3.2e-09 36.5 33.8 5.7e-07 29.4 5.5 4.8 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.27 CBY09655.1 - 6.5e-07 29.5 54.8 0.00076 19.7 10.7 4.3 4 0 0 4 4 4 3 EGF-like domain EGF_MSP1_1 PF12946.7 CBY09655.1 - 6.6e-07 29.3 39.5 0.0034 17.4 6.5 4.7 4 0 0 4 4 4 3 MSP1 EGF domain 1 hEGF PF12661.7 CBY09655.1 - 0.00039 20.9 30.9 0.0034 17.9 5.3 4.5 4 0 0 4 4 4 2 Human growth factor-like EGF Helicase_C_2 PF13307.6 CBY09656.1 - 1.9e-50 171.4 0.0 4.4e-50 170.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBY09656.1 - 3.9e-47 160.1 0.9 6.9e-47 159.3 0.9 1.4 1 0 0 1 1 1 1 DEAD_2 PhoH PF02562.16 CBY09656.1 - 4.2e-06 26.3 0.0 0.0024 17.3 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 CBY09656.1 - 0.00012 22.1 0.0 0.7 9.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CBY09656.1 - 0.0088 15.8 0.0 0.11 12.3 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY09656.1 - 0.03 14.6 0.0 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fzo_mitofusin PF04799.13 CBY09657.1 - 6e-31 107.2 0.6 6e-31 107.2 0.6 3.9 4 0 0 4 4 4 1 fzo-like conserved region Dynamin_N PF00350.23 CBY09657.1 - 1.3e-21 77.4 4.1 9.4e-21 74.6 0.0 3.6 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 CBY09657.1 - 8.9e-06 25.8 0.0 6e-05 23.1 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Phasin PF05597.11 CBY09657.1 - 0.0004 20.4 8.3 0.14 12.2 0.1 3.9 3 0 0 3 3 3 2 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 CBY09657.1 - 0.097 12.5 15.0 0.27 11.1 0.4 4.8 5 1 0 5 5 5 0 Apolipoprotein A1/A4/E domain NOG1_N PF17835.1 CBY09657.1 - 0.14 12.1 5.1 0.091 12.7 0.7 2.8 3 0 0 3 3 3 0 NOG1 N-terminal helical domain Gp-FAR-1 PF05823.12 CBY09657.1 - 0.92 9.9 9.3 0.35 11.2 0.5 3.8 3 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2316 PF10078.9 CBY09657.1 - 2.4 8.4 5.8 4.8 7.5 0.1 3.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) Fib_alpha PF08702.10 CBY09657.1 - 5.3 7.2 13.8 0.74 10.0 2.3 3.8 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family CdvA PF18822.1 CBY09657.1 - 6.4 6.6 16.4 4.9 7.0 0.5 4.6 4 1 0 5 5 5 0 CdvA-like coiled-coil domain YtxH PF12732.7 CBY09657.1 - 9.2 6.9 22.4 6.1 7.5 0.9 5.3 5 1 0 5 5 5 0 YtxH-like protein DUF4795 PF16043.5 CBY09657.1 - 9.3 5.8 13.8 1.5 8.4 3.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Pro_isomerase PF00160.21 CBY09658.1 - 1.7e-46 158.4 0.3 2.1e-46 158.0 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pan3_PK PF18101.1 CBY09660.1 - 1.2e-40 138.6 0.0 2.6e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CBY09660.1 - 5.6e-07 29.2 0.2 1.4e-06 27.9 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09660.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase MOZART1 PF12554.8 CBY09661.1 - 9.9e-14 50.9 0.1 1.3e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated RNase_PH PF01138.21 CBY09662.1 - 5.2e-21 75.5 0.3 7.2e-21 75.1 0.3 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1415 PF07209.12 CBY09662.1 - 0.027 14.2 0.2 0.073 12.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) CREPT PF16566.5 CBY09663.1 - 1.4e-11 44.8 2.2 1.4e-11 44.8 2.2 2.5 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 CBY09663.1 - 2.8e-11 44.0 1.1 1.3e-10 42.0 0.0 2.8 4 0 0 4 4 4 1 RNA polymerase II-binding domain. Med19 PF10278.9 CBY09663.1 - 4.3e-05 23.5 1.8 4.3e-05 23.5 1.8 1.8 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 CTK3 PF12243.8 CBY09663.1 - 0.0038 17.2 0.1 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 Peptidase_S49_N PF08496.10 CBY09663.1 - 0.53 10.3 11.1 0.26 11.3 6.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Thg1C PF14413.6 CBY09663.1 - 2.9 8.0 8.3 1.7 8.8 4.1 2.2 2 0 0 2 2 2 0 Thg1 C terminal domain Ank_2 PF12796.7 CBY09664.1 - 3e-20 72.6 0.0 8.1e-09 35.9 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY09664.1 - 2.9e-10 40.2 0.0 1.2e-06 28.6 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY09664.1 - 4.4e-10 38.9 0.0 0.019 15.5 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 CBY09664.1 - 2.1e-06 28.1 0.0 0.0018 18.8 0.0 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY09664.1 - 2.3e-06 27.8 0.0 0.25 11.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat SOCS_box PF07525.16 CBY09664.1 - 0.00094 19.5 2.2 0.0021 18.4 2.2 1.6 1 0 0 1 1 1 1 SOCS box WD40 PF00400.32 CBY09665.1 - 1.3e-19 70.1 8.4 1.3e-06 29.0 0.6 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09665.1 - 1.6e-09 37.9 0.2 0.00024 21.3 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY09665.1 - 0.00015 21.2 0.1 0.013 14.8 0.3 2.3 2 0 0 2 2 2 2 WD40-like domain F_actin_bind PF08919.10 CBY09665.1 - 0.028 14.5 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 F-actin binding Dscam_C PF12355.8 CBY09665.1 - 0.065 14.2 3.3 0.096 13.7 2.1 1.9 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Ras PF00071.22 CBY09666.1 - 8.8e-55 184.7 0.1 1e-54 184.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY09666.1 - 7.8e-21 74.5 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY09666.1 - 1.7e-10 40.7 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY09666.1 - 0.00012 22.1 1.6 0.16 11.9 0.0 2.1 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY09666.1 - 0.00019 21.0 0.1 0.0009 18.8 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY09666.1 - 0.0041 17.2 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CBY09666.1 - 0.021 14.8 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 CBY09666.1 - 0.12 11.4 0.0 11 5.0 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit zf-B_box PF00643.24 CBY09667.1 - 0.065 13.4 10.7 0.089 13.0 10.7 1.2 1 0 0 1 1 1 0 B-box zinc finger Vps53_N PF04100.12 CBY09668.1 - 0.00041 19.4 0.6 0.00042 19.4 0.6 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal FliT PF05400.13 CBY09668.1 - 0.018 15.8 2.3 0.022 15.5 2.3 1.1 1 0 0 1 1 1 0 Flagellar protein FliT YgaB PF14182.6 CBY09668.1 - 0.037 14.4 0.8 0.044 14.2 0.8 1.1 1 0 0 1 1 1 0 YgaB-like protein TPT PF03151.16 CBY09669.1 - 6.9e-11 42.0 18.6 9.1e-11 41.6 18.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY09669.1 - 0.0035 17.5 34.6 0.2 11.8 15.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family DSPc PF00782.20 CBY09670.1 - 9.3e-14 51.4 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY09670.1 - 0.0074 16.4 0.0 0.046 13.8 0.0 2.0 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBY09670.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY09670.1 - 0.041 13.9 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PriX PF18689.1 CBY09670.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Primase X Ion_trans PF00520.31 CBY09671.1 - 5e-36 124.2 16.6 7.3e-36 123.6 16.6 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CBY09671.1 - 4.4e-18 65.4 0.1 9.4e-17 61.2 0.0 3.0 3 0 0 3 3 3 1 BTB/POZ domain Ion_trans_2 PF07885.16 CBY09671.1 - 1.7e-11 43.9 6.8 1.7e-11 43.9 6.8 2.0 3 0 0 3 3 3 1 Ion channel VWA_3 PF13768.6 CBY09671.1 - 3.5e-07 30.3 0.0 9.9e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY09671.1 - 4.2e-05 24.2 0.0 9.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CBY09671.1 - 0.00065 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain PKD_channel PF08016.12 CBY09671.1 - 0.065 11.9 10.9 1.9 7.1 10.4 2.3 1 1 0 1 1 1 0 Polycystin cation channel Rhodanese PF00581.20 CBY09673.1 - 1.5e-05 25.5 0.0 3.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain HPD PF05044.12 CBY09674.1 - 4.2e-78 260.6 1.7 4.2e-78 260.6 1.7 1.6 2 0 0 2 2 2 1 Homeo-prospero domain Com_YlbF PF06133.11 CBY09674.1 - 0.55 10.9 5.8 0.2 12.3 0.4 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Ion_trans PF00520.31 CBY09675.1 - 2.7e-15 56.3 15.8 3.8e-15 55.8 15.8 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY09675.1 - 2.5e-13 49.9 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.10 CBY09675.1 - 0.084 12.5 1.3 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Ion transport protein N-terminal FYVE PF01363.21 CBY09676.1 - 7.1 6.8 14.1 1.3 9.2 6.2 2.8 2 0 0 2 2 2 0 FYVE zinc finger Vinculin PF01044.19 CBY09677.1 - 3.6e-16 58.6 5.5 3.6e-16 58.6 5.5 1.8 2 0 0 2 2 2 1 Vinculin family Spc7 PF08317.11 CBY09677.1 - 0.12 11.3 31.1 0.0096 14.8 6.1 3.7 3 1 1 4 4 4 0 Spc7 kinetochore protein DUF1664 PF07889.12 CBY09677.1 - 0.26 11.3 20.5 0.18 11.8 5.6 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) CobN-Mg_chel PF02514.16 CBY09677.1 - 0.43 8.2 9.4 0.34 8.6 4.6 2.0 2 0 0 2 2 2 0 CobN/Magnesium Chelatase DUF2730 PF10805.8 CBY09677.1 - 0.69 10.0 11.4 3.7 7.7 3.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) VPS11_C PF12451.8 CBY09677.1 - 8.8 6.7 12.4 3.9 7.8 1.4 4.0 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal HSF_DNA-bind PF00447.17 CBY09678.1 - 1.2e-16 61.1 2.4 2.2e-16 60.2 2.4 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1840 PF08895.11 CBY09678.1 - 0.69 10.3 0.0 0.69 10.3 0.0 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) PAX PF00292.18 CBY09679.1 - 3.5e-69 230.5 0.5 5.7e-69 229.8 0.5 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CBY09679.1 - 9.8e-23 79.8 3.8 2.2e-22 78.7 3.8 1.6 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 CBY09679.1 - 7.1e-05 22.5 1.4 0.00013 21.6 0.0 2.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 CBY09679.1 - 0.00044 20.8 0.2 0.0021 18.6 0.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 CBY09679.1 - 0.0043 16.6 0.1 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 InsA C-terminal domain HTH_28 PF13518.6 CBY09679.1 - 0.039 14.1 0.4 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Homeobox_KN PF05920.11 CBY09679.1 - 0.072 13.0 1.2 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain Glyco_hydro_6 PF01341.17 CBY09680.1 - 4.5e-11 43.0 0.0 1.1e-06 28.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Trypsin PF00089.26 CBY09681.1 - 1.6e-64 217.7 0.2 1.6e-64 217.7 0.2 1.6 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY09681.1 - 0.0029 18.5 0.0 0.0076 17.2 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF4776 PF16003.5 CBY09681.1 - 0.34 9.9 12.8 0.47 9.4 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Cyclin_C PF02984.19 CBY09681.1 - 0.42 10.7 1.5 0.69 10.0 1.5 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain Mucin PF01456.17 CBY09681.1 - 1.5 8.8 14.8 2.5 8.1 14.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PIEZO PF15917.5 CBY09681.1 - 1.8 8.0 9.5 2.6 7.5 9.5 1.2 1 0 0 1 1 1 0 Piezo Collagen PF01391.18 CBY09682.1 - 8.1e-20 70.3 84.0 2.9e-08 33.3 33.2 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY09682.1 - 1.6 9.0 5.6 3 8.1 1.1 2.9 2 1 0 2 2 2 0 von Willebrand factor type A domain SSP160 PF06933.11 CBY09683.1 - 0.16 10.2 4.0 0.22 9.7 4.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BK_channel_a PF03493.18 CBY09684.1 - 3.4e-33 113.7 0.0 7.9e-33 112.6 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 CBY09684.1 - 0.001 19.3 0.0 0.022 15.0 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain zf-H2C2_2 PF13465.6 CBY09685.1 - 3.1e-16 59.0 17.8 7e-10 38.9 0.5 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY09685.1 - 8.4e-14 51.2 21.7 3.4e-05 24.0 0.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY09685.1 - 1.9e-09 37.5 18.3 0.0035 18.0 0.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY09685.1 - 0.0026 17.7 12.7 0.57 10.2 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY09685.1 - 0.0063 16.8 7.4 0.53 10.6 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY09685.1 - 0.014 15.8 8.2 0.59 10.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CBY09685.1 - 0.031 14.2 7.0 0.15 12.0 1.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 CBY09685.1 - 0.044 14.1 3.4 0.079 13.3 3.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 CBY09685.1 - 0.54 10.6 9.0 0.78 10.1 1.2 2.7 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FAM70 PF14967.6 CBY09687.1 - 0.0078 15.7 2.8 0.014 14.9 2.8 1.3 1 0 0 1 1 1 1 FAM70 protein TMEM51 PF15345.6 CBY09687.1 - 0.0082 16.0 0.3 0.015 15.1 0.0 1.5 2 0 0 2 2 2 1 Transmembrane protein 51 T4SS_CagC PF16943.5 CBY09687.1 - 0.02 15.0 3.5 3.6 7.8 1.3 2.4 1 1 0 2 2 2 0 Cag pathogenicity island, type IV secretory system HisKA_7TM PF16927.5 CBY09687.1 - 0.043 13.9 2.1 0.12 12.4 2.1 1.6 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase Trp_oprn_chp PF09534.10 CBY09687.1 - 0.046 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MHYT PF03707.16 CBY09687.1 - 0.098 12.8 1.3 2.4 8.4 0.2 2.8 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat Jiraiya PF15038.6 CBY09687.1 - 0.18 11.2 3.8 1.7 8.1 0.0 2.8 3 0 0 3 3 3 0 Jiraiya DUF3810 PF12725.7 CBY09687.1 - 1.8 7.8 4.0 2.5 7.3 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF202 PF02656.15 CBY09687.1 - 1.9 9.0 5.9 23 5.5 4.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Enkurin PF13864.6 CBY09689.1 - 0.013 15.9 5.1 0.013 15.9 5.1 2.6 3 0 0 3 3 3 0 Calmodulin-binding Mod_r PF07200.13 CBY09689.1 - 0.041 14.0 6.0 0.018 15.1 2.2 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1843 PF08898.10 CBY09689.1 - 0.11 13.1 3.3 0.18 12.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) SLATT_4 PF18186.1 CBY09689.1 - 1.7 8.2 4.1 3.9 7.1 0.1 3.0 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 Abhydrolase_3 PF07859.13 CBY09690.1 - 2.1e-07 31.0 0.0 2.6e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold WD40 PF00400.32 CBY09691.1 - 1.8e-11 44.4 4.8 0.025 15.5 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09691.1 - 0.0025 18.1 0.1 1.8 8.9 0.1 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY09691.1 - 0.017 14.5 0.3 0.36 10.1 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Lectin_N PF03954.14 CBY09692.1 - 0.35 10.6 6.5 1.3 8.8 0.3 3.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF4600 PF15372.6 CBY09692.1 - 3.8 8.0 30.5 0.12 12.8 10.1 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4600) DEAD PF00270.29 CBY09693.1 - 1.7e-49 167.9 0.0 4.3e-49 166.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY09693.1 - 5.3e-25 87.9 0.4 3.9e-23 81.9 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CBY09693.1 - 8.7e-12 45.1 4.0 8.7e-12 45.1 4.0 2.9 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ImmE5 PF11480.8 CBY09693.1 - 0.053 14.0 2.8 0.75 10.3 0.1 3.1 2 1 1 3 3 3 0 Colicin-E5 Imm protein TCTP PF00838.17 CBY09693.1 - 0.057 13.8 2.1 0.19 12.1 0.9 2.4 2 0 0 2 2 2 0 Translationally controlled tumour protein Folate_rec PF03024.14 CBY09695.1 - 8.5e-09 35.5 19.2 3.5e-08 33.5 19.2 2.0 1 1 0 1 1 1 1 Folate receptor family Glycophorin_A PF01102.18 CBY09695.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Sulfatase PF00884.23 CBY09696.1 - 1e-62 212.3 0.3 2e-62 211.4 0.3 1.5 1 1 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 CBY09696.1 - 0.0015 18.4 0.8 0.038 13.9 0.8 2.4 1 1 0 1 1 1 1 Domain of unknown function Sulfatase_C PF14707.6 CBY09696.1 - 0.02 15.6 0.0 0.063 14.0 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase UIM PF02809.20 CBY09697.1 - 0.0051 16.6 0.8 0.0051 16.6 0.8 2.0 2 0 0 2 2 2 1 Ubiquitin interaction motif UBX PF00789.20 CBY09697.1 - 0.0087 16.2 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 UBX domain Topoisom_bac PF01131.20 CBY09698.1 - 8e-103 344.6 0.0 1e-102 344.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 CBY09698.1 - 2.4e-22 78.8 19.3 2.6e-14 53.0 2.5 3.3 4 0 0 4 4 4 2 GRF zinc finger Toprim PF01751.22 CBY09698.1 - 4.2e-17 62.2 0.0 8.6e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 CBY09698.1 - 9.3e-05 22.1 6.3 9.3e-05 22.1 6.3 3.6 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.23 CBY09698.1 - 0.31 11.2 4.9 1.2 9.4 4.9 2.1 1 0 0 1 1 1 0 Zinc knuckle RabGAP-TBC PF00566.18 CBY09700.1 - 3.7e-50 170.6 1.6 3.7e-50 170.6 1.6 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 CBY09700.1 - 6.8e-23 82.0 0.0 1.6e-21 77.6 0.0 2.9 2 1 0 2 2 2 1 Kinesin protein Ig_GlcNase PF18368.1 CBY09700.1 - 0.00013 22.0 0.0 0.00067 19.8 0.0 2.2 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Sfi1_C PF10638.9 CBY09700.1 - 1.7 9.4 7.7 0.9 10.3 0.7 2.9 3 0 0 3 3 3 0 Spindle body associated protein C-terminus EAP30 PF04157.16 CBY09702.1 - 6.3e-58 195.9 0.0 7.3e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family CENP-H PF05837.12 CBY09702.1 - 0.015 15.7 0.2 0.029 14.8 0.2 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) WH1 PF00568.23 CBY09705.1 - 7e-13 48.5 0.1 1.2e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 WH1 domain I-set PF07679.16 CBY09706.1 - 7.3e-36 122.1 0.7 6.6e-07 29.3 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.21 CBY09706.1 - 2.5e-32 111.1 0.0 8.5e-13 48.5 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.6 CBY09706.1 - 4.1e-20 72.2 0.3 0.00021 21.9 0.1 6.3 6 0 0 6 6 6 3 Immunoglobulin domain V-set PF07686.17 CBY09706.1 - 2.5e-07 30.8 0.2 0.36 11.0 0.0 4.8 5 0 0 5 5 5 2 Immunoglobulin V-set domain Ig_2 PF13895.6 CBY09706.1 - 6.1e-07 29.7 0.1 2.1 8.7 0.0 5.1 6 0 0 6 6 6 2 Immunoglobulin domain EF-hand_1 PF00036.32 CBY09706.1 - 0.012 15.1 0.3 0.039 13.5 0.3 1.9 1 0 0 1 1 1 0 EF hand ig PF00047.25 CBY09706.1 - 0.014 15.5 0.3 6.4 7.0 0.0 4.1 5 0 0 5 5 5 0 Immunoglobulin domain EF-hand_5 PF13202.6 CBY09706.1 - 0.022 14.2 0.5 0.067 12.7 0.5 1.8 1 0 0 1 1 1 0 EF hand Receptor_2B4 PF11465.8 CBY09706.1 - 0.048 13.9 0.0 12 6.2 0.0 3.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 CBY09706.1 - 0.051 13.6 0.6 0.88 9.7 0.0 2.8 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain EF-hand_8 PF13833.6 CBY09706.1 - 0.087 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Ribophorin_II PF05817.14 CBY09706.1 - 0.29 9.6 0.4 1.3 7.5 0.1 1.9 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II Nif11 PF07862.11 CBY09707.1 - 0.074 13.4 2.8 0.54 10.6 0.2 3.5 2 0 0 2 2 2 0 Nif11 domain Glu-tRNAGln PF02686.15 CBY09707.1 - 0.61 10.4 4.9 1.6 9.1 0.1 4.3 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit EF-hand_1 PF00036.32 CBY09709.1 - 1.1e-16 59.0 17.9 0.0007 19.0 0.1 6.5 6 2 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 CBY09709.1 - 5.7e-15 55.5 19.2 1.7e-08 34.8 0.9 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY09709.1 - 2.8e-14 51.8 14.0 0.0042 16.5 0.1 6.0 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CBY09709.1 - 9.7e-11 40.7 14.9 0.14 12.2 0.1 6.3 5 1 1 6 6 6 5 EF-hand domain EF-hand_8 PF13833.6 CBY09709.1 - 1.9e-07 30.8 14.6 0.026 14.4 0.2 5.3 5 0 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY09709.1 - 8.8e-06 26.0 14.8 0.0037 17.6 2.5 3.7 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Adenine_glyco PF03352.13 CBY09709.1 - 8e-05 22.5 0.3 0.00017 21.4 0.3 1.5 1 0 0 1 1 1 1 Methyladenine glycosylase EF-hand_10 PF14788.6 CBY09709.1 - 0.024 14.5 0.3 0.024 14.5 0.3 4.2 5 0 0 5 5 5 0 EF hand Unstab_antitox PF09720.10 CBY09709.1 - 1.9 8.6 6.0 4.5 7.4 1.0 3.3 3 0 0 3 3 3 0 Putative addiction module component Pkinase PF00069.25 CBY09710.1 - 5.3e-57 193.2 0.0 6.7e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09710.1 - 2.7e-28 99.0 0.0 4.4e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY09710.1 - 1.5e-05 24.2 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY09710.1 - 0.00045 19.6 0.1 0.0035 16.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBY09710.1 - 0.016 15.2 0.2 0.033 14.1 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CBY09710.1 - 0.15 11.4 0.2 0.31 10.4 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GPHH PF16905.5 CBY09710.1 - 0.16 11.8 0.0 0.56 10.0 0.0 2.0 1 1 1 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated DUF4064 PF13273.6 CBY09711.1 - 2.1e-05 24.8 3.6 0.011 15.9 0.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) Claudin_2 PF13903.6 CBY09711.1 - 0.021 14.6 2.3 0.1 12.4 2.3 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CBY09711.1 - 3.4 7.5 7.5 32 4.3 5.2 2.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Ras PF00071.22 CBY09712.1 - 4.4e-45 153.2 0.0 9.1e-45 152.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY09712.1 - 2.9e-27 95.2 0.0 8.8e-27 93.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY09712.1 - 3.9e-17 62.2 0.1 3.9e-17 62.2 0.1 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 CBY09712.1 - 5.6e-07 29.2 0.1 1.7e-05 24.4 0.1 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CBY09712.1 - 1.6e-05 24.4 0.0 1.6e-05 24.4 0.0 2.5 2 2 0 3 3 3 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY09712.1 - 3.8e-05 23.7 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY09712.1 - 4.3e-05 23.5 1.3 0.09 12.7 0.0 2.9 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 CBY09712.1 - 0.00084 18.8 0.0 0.00084 18.8 0.0 3.2 2 2 1 3 3 3 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY09712.1 - 0.0052 16.3 0.1 0.034 13.7 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF3726 PF12525.8 CBY09712.1 - 0.084 13.0 1.0 2.3 8.4 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3726) bMG3 PF11974.8 CBY09712.1 - 0.086 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Exonuc_VII_L PF02601.15 CBY09712.1 - 4 6.9 10.5 6.8 6.2 10.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit SSF PF00474.17 CBY09713.1 - 4e-108 361.9 24.5 5.6e-70 236.2 0.7 2.3 3 0 0 3 3 3 2 Sodium:solute symporter family Nitr_red_assoc PF09655.10 CBY09713.1 - 0.0026 18.4 1.3 0.0043 17.7 1.3 1.2 1 0 0 1 1 1 1 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Neur_chan_memb PF02932.16 CBY09713.1 - 0.061 13.4 0.1 0.061 13.4 0.1 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GAPT PF11770.8 CBY09713.1 - 0.27 11.1 2.7 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) Sulfotransfer_2 PF03567.14 CBY09714.1 - 9.3e-24 84.7 2.0 1.6e-23 83.9 2.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family CBFD_NFYB_HMF PF00808.23 CBY09718.1 - 1.6e-14 54.0 0.7 2.3e-14 53.4 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY09718.1 - 0.00012 22.5 0.2 0.00012 22.5 0.2 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 CBY09718.1 - 0.03 14.4 0.2 0.049 13.7 0.2 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Rap_GAP PF02145.15 CBY09719.1 - 5.9e-54 182.4 0.1 1.1e-53 181.6 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.24 CBY09719.1 - 1.6e-08 34.8 0.1 3.6e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY09719.1 - 9.4e-07 28.6 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY09719.1 - 0.015 15.6 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Lzipper-MIP1 PF14389.6 CBY09719.1 - 0.067 13.5 0.6 0.26 11.6 0.6 2.0 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Rootletin PF15035.6 CBY09719.1 - 0.14 12.2 4.0 0.19 11.7 2.7 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 CBY09719.1 - 0.96 9.3 3.1 1.8 8.4 2.0 2.0 2 0 0 2 2 2 0 Septum formation initiator OTU PF02338.19 CBY09720.1 - 2e-23 83.2 0.0 2e-23 83.2 0.0 2.3 3 0 0 3 3 3 1 OTU-like cysteine protease Draxin PF15550.6 CBY09720.1 - 1.6 8.6 11.8 2 8.2 11.8 1.2 1 0 0 1 1 1 0 Draxin Ndc1_Nup PF09531.10 CBY09720.1 - 1.6 7.3 4.7 1.9 7.1 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AIF-MLS PF14962.6 CBY09720.1 - 4.9 7.1 11.6 4.3 7.3 10.2 1.6 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Thioredoxin PF00085.20 CBY09721.1 - 2e-33 114.5 0.0 1e-31 109.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 CBY09721.1 - 7.8e-25 87.8 0.0 9.6e-21 74.5 0.1 2.5 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY09721.1 - 0.00031 20.9 0.0 0.00099 19.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBY09721.1 - 0.0005 20.5 0.0 0.0019 18.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY09721.1 - 0.0028 17.6 0.1 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CBY09721.1 - 0.0091 16.3 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CBY09721.1 - 0.0099 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Molydop_binding PF01568.21 CBY09721.1 - 0.2 11.7 0.3 0.48 10.5 0.1 1.6 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain TNFR_16_TM PF18422.1 CBY09722.1 - 0.15 12.0 0.8 0.22 11.5 0.8 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain OATP PF03137.20 CBY09723.1 - 2.2e-80 270.5 8.7 2.9e-80 270.1 8.7 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CBY09723.1 - 3.3e-14 52.6 11.2 3.3e-14 52.6 11.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.32 CBY09724.1 - 1.2e-36 124.0 21.3 2.4e-06 28.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09724.1 - 3e-11 43.5 0.1 0.0023 18.2 0.1 4.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3668 PF12416.8 CBY09725.1 - 5.4e-19 68.9 2.3 2.1e-17 63.7 0.0 3.9 3 2 0 3 3 3 1 Cep120 protein DUF4497 PF14924.6 CBY09725.1 - 0.0055 17.1 0.1 0.12 12.8 0.0 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF4497) C2 PF00168.30 CBY09725.1 - 0.035 14.4 0.0 15 5.9 0.0 3.0 2 1 0 2 2 2 0 C2 domain DUF4537 PF15057.6 CBY09726.1 - 1.4e-56 189.7 2.2 9.3e-30 103.1 0.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 CBY09726.1 - 7.9e-06 25.6 0.0 1.9 8.4 0.0 4.2 4 0 0 4 4 4 2 DNA repair protein Crb2 Tudor domain DUF4819 PF16090.5 CBY09726.1 - 0.0015 18.6 0.5 19 5.4 0.0 4.0 2 2 2 4 4 4 2 Domain of unknown function (DUF4819) Tudor_2 PF18104.1 CBY09726.1 - 0.0076 15.9 0.5 1.2 8.9 0.0 4.4 5 0 0 5 5 5 1 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 CBY09726.1 - 0.051 13.3 0.1 1.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain 1 Tox-ODYAM1 PF15642.6 CBY09727.1 - 0.069 12.1 9.3 0.08 11.9 9.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Tugs PF17840.1 CBY09727.1 - 0.78 10.0 4.4 6 7.1 0.5 2.4 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain TMPIT PF07851.13 CBY09727.1 - 1.7 7.8 8.9 1.9 7.7 8.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4570 PF15134.6 CBY09727.1 - 3.8 7.6 14.7 5.4 7.1 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) DNA_pol_A_exo1 PF01612.20 CBY09728.1 - 5.1e-42 143.6 0.3 1.2e-41 142.3 0.3 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CBY09728.1 - 1.8e-11 44.6 0.0 5.4e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 CBY09728.1 - 7.1e-09 35.5 0.0 1.6e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DUF3638 PF12340.8 CBY09728.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) PET117 PF15786.5 CBY09729.1 - 3.5e-14 52.8 0.8 4.3e-14 52.5 0.8 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF2514 PF10721.9 CBY09729.1 - 0.0021 18.1 0.9 0.0023 18.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) DUF4570 PF15134.6 CBY09729.1 - 0.1 12.6 3.6 0.15 12.1 3.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) LptF_LptG PF03739.14 CBY09729.1 - 0.15 10.9 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Pam16 PF03656.13 CBY09730.1 - 0.00049 20.1 0.2 0.00064 19.7 0.2 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 CBY09730.1 - 0.0012 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain RhoGAP PF00620.27 CBY09731.1 - 8.2e-34 116.6 0.0 1.9e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain SH3_9 PF14604.6 CBY09731.1 - 5.9e-05 22.8 0.0 0.00028 20.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY09731.1 - 0.00046 19.7 0.1 0.0013 18.3 0.1 1.8 1 0 0 1 1 1 1 SH3 domain RNF111_N PF15303.6 CBY09731.1 - 0.011 15.6 1.3 0.011 15.6 1.3 2.3 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Yip1 PF04893.17 CBY09732.1 - 1.6e-09 37.7 15.5 2.9e-09 36.9 15.4 1.5 1 1 0 1 1 1 1 Yip1 domain TMEM252 PF15664.5 CBY09732.1 - 0.054 13.2 1.3 0.79 9.4 0.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 252 family CO_dh PF02552.16 CBY09733.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Ofd1_CTDD PF10637.9 CBY09734.1 - 1.2e-25 90.3 0.1 5.2e-24 85.0 0.0 2.5 2 1 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CBY09734.1 - 0.00051 20.7 0.1 0.075 13.7 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Ion_trans_2 PF07885.16 CBY09739.1 - 1.3e-05 25.1 1.8 2.8e-05 24.0 1.8 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CBY09739.1 - 0.024 13.9 0.3 0.081 12.1 0.0 1.9 2 0 0 2 2 2 0 Ion transport protein Nnf1 PF03980.14 CBY09739.1 - 1 9.8 6.9 0.33 11.4 2.9 2.2 2 0 0 2 2 2 0 Nnf1 Ribosomal_S3_C PF00189.20 CBY09740.1 - 2.1e-24 85.8 1.6 1.9e-23 82.8 1.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CBY09740.1 - 5e-11 42.3 0.4 9.6e-11 41.4 0.4 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 CBY09740.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus zf-C3HC4 PF00097.25 CBY09741.1 - 4.5e-09 36.0 8.5 4.5e-09 36.0 8.5 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY09741.1 - 5.3e-09 36.0 6.8 1.1e-08 34.9 6.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY09741.1 - 7.6e-08 32.6 8.9 7.6e-08 32.6 8.9 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY09741.1 - 8.9e-08 31.9 6.0 1.8e-07 30.9 6.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY09741.1 - 6.7e-07 29.1 9.3 6.7e-07 29.1 9.3 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY09741.1 - 4.9e-06 26.3 7.8 0.00021 21.1 8.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CBY09741.1 - 9.6e-06 25.7 7.8 1.9e-05 24.7 7.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 CBY09741.1 - 0.00012 22.0 1.7 0.00023 21.1 1.7 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 CBY09741.1 - 0.00029 20.8 8.8 0.0011 18.9 8.8 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 CBY09741.1 - 0.0016 18.1 4.1 0.0066 16.2 4.1 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF4428 PF14471.6 CBY09741.1 - 0.015 15.2 2.4 3.4 7.7 1.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) DZR PF12773.7 CBY09741.1 - 0.058 13.4 3.1 0.22 11.6 3.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 CBY09741.1 - 0.06 13.4 2.3 0.06 13.4 2.3 1.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Fer2 PF00111.27 CBY09741.1 - 0.13 12.2 1.6 1.8 8.6 1.6 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-RING_11 PF17123.5 CBY09741.1 - 0.19 11.5 7.5 0.68 9.7 7.5 2.0 1 1 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 CBY09741.1 - 0.54 10.6 11.0 1.9 8.9 9.3 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-piccolo PF05715.13 CBY09741.1 - 0.89 9.8 6.3 6.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger PsbM PF05151.12 CBY09741.1 - 6.1 6.7 12.6 1.2 9.0 8.8 1.8 1 1 1 2 2 2 0 Photosystem II reaction centre M protein (PsbM) zf-C3HC4 PF00097.25 CBY09742.1 - 9.9e-08 31.7 8.5 4e-07 29.8 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY09742.1 - 4.7e-07 29.7 7.0 1.3e-05 25.1 2.8 2.3 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY09742.1 - 5.4e-07 29.3 2.9 5.4e-07 29.3 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY09742.1 - 5.6e-07 29.8 7.3 8.7e-07 29.2 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY09742.1 - 8.5e-06 25.5 7.9 3.6e-05 23.5 7.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY09742.1 - 0.00012 22.2 8.4 0.0011 19.1 8.9 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CBY09742.1 - 0.0014 18.5 9.3 0.06 13.3 10.6 2.5 1 1 1 2 2 2 1 zinc-RING finger domain zf-4CXXC_R1 PF10497.9 CBY09742.1 - 0.064 13.5 5.4 0.15 12.3 5.5 1.5 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Prok-RING_4 PF14447.6 CBY09742.1 - 0.12 12.3 8.1 1.7 8.6 8.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 CBY09742.1 - 0.13 12.1 0.9 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 CBY09742.1 - 0.23 11.3 7.0 0.54 10.1 4.2 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 CBY09742.1 - 0.29 11.5 2.9 5.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ANAPC11 PF12861.7 CBY09742.1 - 0.49 10.5 4.2 1.9 8.6 4.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CBY09742.1 - 1.1 9.6 11.0 10 6.5 11.0 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain Pkinase PF00069.25 CBY09743.1 - 2.8e-55 187.5 0.9 5.1e-55 186.7 0.0 2.0 2 1 1 3 3 3 1 Protein kinase domain CNH PF00780.22 CBY09743.1 - 2.8e-30 105.9 0.1 3.7e-29 102.2 0.0 2.6 2 0 0 2 2 2 1 CNH domain Pkinase_Tyr PF07714.17 CBY09743.1 - 8.5e-30 103.9 0.0 2.2e-29 102.5 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CBY09743.1 - 3.6e-09 36.4 4.0 7e-09 35.4 4.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 CBY09743.1 - 1.9e-07 30.7 0.0 4.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CBY09743.1 - 1.5e-05 25.6 1.3 5e-05 23.9 1.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain PBD PF00786.28 CBY09743.1 - 4.8e-05 23.6 0.5 0.28 11.6 0.1 3.3 2 0 0 2 2 2 2 P21-Rho-binding domain PH PF00169.29 CBY09743.1 - 0.00046 20.7 2.5 0.0011 19.5 0.0 3.0 3 0 0 3 3 3 1 PH domain APH PF01636.23 CBY09743.1 - 0.046 13.6 0.1 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family C1_2 PF03107.16 CBY09743.1 - 0.089 13.1 2.4 0.21 11.9 2.4 1.6 1 0 0 1 1 1 0 C1 domain Golgin_A5 PF09787.9 CBY09743.1 - 0.36 10.3 51.3 0.27 10.6 2.5 3.4 2 1 1 3 3 3 0 Golgin subfamily A member 5 Prok-RING_1 PF14446.6 CBY09743.1 - 2.6 8.1 5.2 7.7 6.5 5.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Kinesin PF00225.23 CBY09744.1 - 8.6e-118 393.1 4.3 8.6e-118 393.1 4.3 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY09744.1 - 8.5e-30 103.7 0.4 8.5e-30 103.7 0.4 2.1 2 1 1 3 3 3 1 Microtubule binding V_ATPase_I PF01496.19 CBY09744.1 - 0.16 9.9 21.8 0.31 8.9 21.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_16 PF13191.6 CBY09744.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain HAUS-augmin3 PF14932.6 CBY09744.1 - 1 8.9 28.6 0.15 11.6 12.5 2.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TUSC2 PF15000.6 CBY09745.1 - 3.9e-08 33.6 0.0 5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Tumour suppressor candidate 2 TPD PF14811.6 CBY09746.1 - 2.9e-48 163.2 0.1 4.8e-48 162.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif Transketolase_N PF00456.21 CBY09747.1 - 3.9e-47 160.9 0.3 9.1e-47 159.6 0.3 1.6 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CBY09747.1 - 1.1e-34 119.6 0.0 2e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBY09747.1 - 3.4e-30 104.5 1.6 9.9e-30 103.0 0.9 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 CBY09747.1 - 9.8e-13 47.7 0.0 2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CBY09747.1 - 7.5e-06 25.3 0.0 0.0002 20.7 0.0 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 CBY09747.1 - 0.0029 17.4 4.7 0.035 13.9 0.5 3.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 CBY09747.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain PFOR_II PF17147.4 CBY09747.1 - 0.064 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II SAM_1 PF00536.30 CBY09749.1 - 1.1e-08 35.4 0.0 3.3e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY09749.1 - 3.1e-05 24.0 0.0 7.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 CBY09749.1 - 0.00016 21.5 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PHAT PF09246.10 CBY09749.1 - 0.064 13.1 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 PHAT TylF PF05711.11 CBY09749.1 - 0.13 11.5 0.5 6.5 5.9 0.0 2.5 3 0 0 3 3 3 0 Macrocin-O-methyltransferase (TylF) RELT PF12606.8 CBY09751.1 - 1.1 8.3 3.6 10 5.2 0.2 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Shisa PF13908.6 CBY09753.1 - 0.0034 17.7 0.0 0.0038 17.5 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 CBY09753.1 - 0.0096 15.7 1.7 0.014 15.2 1.7 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Cadherin_C_2 PF16492.5 CBY09753.1 - 0.012 16.3 0.0 0.019 15.7 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Tweety PF04906.13 CBY09753.1 - 0.026 13.2 0.1 0.033 12.8 0.1 1.1 1 0 0 1 1 1 0 Tweety TMEM132D_C PF15706.5 CBY09753.1 - 0.045 13.5 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SID-1_RNA_chan PF13965.6 CBY09753.1 - 0.06 11.8 0.0 0.062 11.7 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ETRAMP PF09716.10 CBY09753.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TMEM52 PF14979.6 CBY09753.1 - 0.12 12.2 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Transmembrane 52 VWA PF00092.28 CBY09754.1 - 4.8e-16 59.5 0.7 7.7e-16 58.8 0.7 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Phospholip_A2_1 PF00068.19 CBY09754.1 - 3.1e-13 50.2 3.8 3.1e-13 50.2 3.8 2.4 2 0 0 2 2 2 1 Phospholipase A2 VWA_2 PF13519.6 CBY09754.1 - 6.2e-07 30.0 0.1 1.6e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY09754.1 - 0.019 14.4 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein GATA PF00320.27 CBY09755.1 - 7.6e-05 22.2 5.5 0.0032 17.1 1.3 3.6 4 0 0 4 4 4 2 GATA zinc finger Zn_ribbon_SprT PF17283.2 CBY09755.1 - 0.0062 16.4 1.0 0.02 14.8 1.0 1.9 1 0 0 1 1 1 1 SprT-like zinc ribbon domain zf-RING_10 PF16685.5 CBY09755.1 - 0.029 14.5 3.2 0.06 13.5 3.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 OrfB_Zn_ribbon PF07282.11 CBY09755.1 - 0.063 13.2 1.3 0.063 13.2 1.3 2.3 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.12 CBY09755.1 - 0.13 12.6 3.8 0.12 12.7 1.4 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Zn-ribbon_8 PF09723.10 CBY09755.1 - 0.15 12.2 8.0 2.8 8.1 0.0 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DUF3268 PF11672.8 CBY09755.1 - 0.15 12.4 3.7 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 zinc-finger-containing domain HypA PF01155.19 CBY09755.1 - 0.22 11.6 10.5 0.97 9.5 4.9 2.9 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CBY09755.1 - 1.8 8.7 13.0 1.4 9.0 9.0 2.5 2 1 1 3 3 3 0 Double zinc ribbon zf-TFIIB PF13453.6 CBY09755.1 - 4.1 6.8 6.3 0.57 9.6 1.8 1.9 2 0 0 2 2 2 0 Transcription factor zinc-finger DnaJ_CXXCXGXG PF00684.19 CBY09755.1 - 7.3 7.0 13.3 2.9 8.3 9.5 2.2 1 1 1 2 2 2 0 DnaJ central domain Mab-21 PF03281.14 CBY09756.1 - 2e-78 263.7 0.0 2.4e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein FKBP_C PF00254.28 CBY09758.1 - 2.3e-09 37.4 0.0 5.1e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_5 PF13202.6 CBY09758.1 - 0.0017 17.8 0.2 0.0017 17.8 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY09758.1 - 0.0023 17.7 0.9 0.0092 15.8 0.3 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY09758.1 - 0.0028 17.1 0.7 0.0084 15.6 0.1 2.0 2 0 0 2 2 2 1 EF hand PRESAN PF09687.10 CBY09758.1 - 0.01 16.4 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 0 Plasmodium RESA N-terminal EF-hand_7 PF13499.6 CBY09758.1 - 0.055 13.9 1.7 0.11 13.0 0.3 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 CBY09758.1 - 0.13 12.1 0.2 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair SHOCT PF09851.9 CBY09758.1 - 0.17 11.6 0.6 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Short C-terminal domain Ig_2 PF13895.6 CBY09759.1 - 6.4e-06 26.4 1.5 0.074 13.4 0.4 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 CBY09759.1 - 1.2e-05 25.8 2.9 0.085 13.5 1.3 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 CBY09759.1 - 0.05 13.6 0.9 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 C17orf99 Ig domain PRA1 PF03208.19 CBY09760.1 - 0.31 10.7 12.6 0.4 10.3 7.7 2.1 1 1 1 2 2 2 0 PRA1 family protein zf-C2H2 PF00096.26 CBY09761.1 - 9.2e-32 107.7 92.2 9e-06 25.9 1.5 11.2 10 1 1 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY09761.1 - 2.6e-23 80.7 80.2 0.00077 20.1 0.6 10.9 10 1 1 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY09761.1 - 5.3e-17 61.4 90.0 2.7e-08 33.8 0.2 11.9 14 0 0 14 14 14 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY09761.1 - 3.9e-12 46.1 55.1 0.019 15.3 3.3 9.7 10 0 0 10 10 9 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY09761.1 - 8.7e-05 22.8 63.8 0.0064 16.9 0.4 9.9 10 0 0 10 10 10 5 Zinc-finger of C2H2 type BolA PF01722.18 CBY09761.1 - 0.00013 22.2 9.3 0.069 13.4 0.0 4.4 3 2 2 5 5 5 2 BolA-like protein zf-C2H2_6 PF13912.6 CBY09761.1 - 0.0074 16.3 7.8 0.012 15.6 2.1 9.4 10 0 0 10 10 10 3 C2H2-type zinc finger zf-MYST PF17772.1 CBY09761.1 - 0.0097 15.5 44.6 0.67 9.6 1.0 9.5 5 3 5 10 10 10 4 MYST family zinc finger domain zf-C2HE PF16278.5 CBY09761.1 - 0.013 15.9 0.6 0.013 15.9 0.6 7.4 5 2 3 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 CBY09761.1 - 0.028 14.2 0.1 0.028 14.2 0.1 7.4 8 0 0 8 8 8 0 zinc-finger C2H2-type GAGA PF09237.11 CBY09761.1 - 0.72 9.7 12.1 5.4 6.9 0.1 4.8 4 2 1 5 5 5 0 GAGA factor zf-C2HC_2 PF13913.6 CBY09761.1 - 6.7 6.7 35.5 0.61 10.1 0.8 7.2 7 0 0 7 7 7 0 zinc-finger of a C2HC-type UPF0444 PF15475.6 CBY09762.1 - 7.9 6.8 42.8 0.52 10.6 13.7 2.3 1 1 1 2 2 2 0 Transmembrane protein C12orf23, UPF0444 PDZ_6 PF17820.1 CBY09763.1 - 1.1e-09 38.0 0.0 2.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY09763.1 - 1.3e-06 28.6 0.0 3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY09763.1 - 1.7e-06 28.2 0.0 4.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF3461 PF11944.8 CBY09763.1 - 0.33 11.1 3.9 0.84 9.8 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) PspB PF06667.12 CBY09763.1 - 1.2 9.2 2.8 3.1 7.9 2.8 1.6 1 0 0 1 1 1 0 Phage shock protein B PID PF00640.23 CBY09765.1 - 1.5e-07 31.5 0.0 3.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 CBY09765.1 - 5.1e-07 29.7 0.1 1.6e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 SH2 domain Abhydrolase_1 PF00561.20 CBY09766.1 - 5.7e-14 52.4 0.0 3.5e-08 33.4 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY09766.1 - 2.4e-09 38.1 0.0 2.7e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBY09766.1 - 2e-05 24.0 0.0 0.062 12.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 CBY09766.1 - 0.00018 21.1 0.1 0.00049 19.7 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CBY09766.1 - 0.00021 20.8 0.7 0.005 16.4 0.7 2.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 CBY09766.1 - 0.045 13.4 0.1 0.2 11.3 0.1 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 CBY09766.1 - 0.072 12.9 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold TDH PF03347.13 CBY09766.1 - 0.17 11.4 0.2 0.33 10.5 0.1 1.4 1 1 0 1 1 1 0 Vibrio thermostable direct hemolysin MIT PF04212.18 CBY09769.1 - 1.1e-18 67.0 6.7 2.1e-18 66.1 6.7 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 CBY09769.1 - 0.023 15.0 1.2 0.51 10.7 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY09769.1 - 0.058 13.5 0.3 0.058 13.5 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY09769.1 - 0.059 13.4 1.0 1.5 9.0 0.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat GST_C_3 PF14497.6 CBY09769.1 - 0.091 13.0 0.2 0.28 11.4 0.2 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TPR_1 PF00515.28 CBY09769.1 - 0.094 12.6 0.2 0.094 12.6 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PAN_4 PF14295.6 CBY09770.1 - 0.0075 16.2 5.1 0.016 15.1 1.3 2.4 2 0 0 2 2 2 2 PAN domain UTP25 PF06862.12 CBY09771.1 - 2.1e-103 346.6 9.2 2.3e-70 237.7 2.5 2.1 1 1 1 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF3826 PF12875.7 CBY09771.1 - 0.00012 22.3 0.8 0.00035 20.8 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) PI3K_1B_p101 PF10486.9 CBY09771.1 - 3.6 5.2 9.7 0.55 8.0 5.1 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit dsrm PF00035.26 CBY09772.1 - 7.2e-11 42.6 0.6 2.4 8.9 0.0 6.4 6 0 0 6 6 6 4 Double-stranded RNA binding motif CSTF2_hinge PF14327.6 CBY09773.1 - 4.9e-21 75.0 6.0 4.9e-21 75.0 6.0 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 CBY09773.1 - 1.3e-16 59.9 12.0 1.3e-16 59.9 12.0 1.9 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 CBY09773.1 - 2.9e-13 49.4 0.1 5.1e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.25 CBY09774.1 - 4.2e-08 32.8 0.1 1.8e-07 30.8 0.0 2.1 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CBY09774.1 - 4.6e-07 30.7 5.4 1.1e-06 29.5 5.4 1.7 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF747 PF05346.11 CBY09775.1 - 4.1e-82 276.2 26.9 5e-82 275.9 26.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PRA1 PF03208.19 CBY09776.1 - 1.4e-34 118.8 0.0 1.7e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 PRA1 family protein FERM_M PF00373.18 CBY09777.1 - 1.1e-16 61.3 0.1 3.7e-16 59.6 0.1 2.0 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 CBY09777.1 - 1.4e-16 60.6 0.1 5e-16 58.9 0.1 2.0 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CBY09777.1 - 1.4e-10 40.9 2.5 5.2e-10 39.1 0.1 2.8 3 0 0 3 3 3 1 FERM N-terminal domain DDE_Tnp_1_4 PF13701.6 CBY09777.1 - 0.0053 15.1 0.3 0.0085 14.4 0.3 1.2 1 0 0 1 1 1 1 Transposase DDE domain group 1 RGS PF00615.19 CBY09777.1 - 0.033 14.5 0.5 0.98 9.7 0.0 2.7 2 0 0 2 2 2 0 Regulator of G protein signaling domain CALCOCO1 PF07888.11 CBY09777.1 - 0.047 12.6 19.1 0.076 11.9 19.1 1.3 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2514 PF10721.9 CBY09777.1 - 0.21 11.6 2.0 0.4 10.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RRM_1 PF00076.22 CBY09778.1 - 5.4e-23 80.6 0.0 1.4e-06 28.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY09778.1 - 0.00075 19.5 0.3 0.96 9.5 0.0 2.7 3 0 0 3 3 3 2 RNA binding motif YhdX PF17444.2 CBY09778.1 - 0.076 12.9 3.3 0.12 12.3 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized YhdX-like HLH PF00010.26 CBY09780.1 - 3.2e-12 46.2 0.7 3.2e-12 46.2 0.7 2.3 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain PikAIV_N PF18605.1 CBY09780.1 - 0.043 13.4 2.6 0.1 12.2 2.6 1.7 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Spectrin PF00435.21 CBY09780.1 - 0.061 13.8 0.1 0.22 12.0 0.1 1.9 1 0 0 1 1 1 0 Spectrin repeat HMMR_N PF15905.5 CBY09780.1 - 0.074 12.5 5.8 0.15 11.5 5.8 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CCDC92 PF14916.6 CBY09780.1 - 0.083 12.7 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF3937 PF13073.6 CBY09780.1 - 0.15 12.2 0.4 0.39 10.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) DivIC PF04977.15 CBY09780.1 - 0.49 10.2 3.6 1.3 8.9 2.4 2.4 1 1 0 1 1 1 0 Septum formation initiator RNA_pol_Rpc4 PF05132.14 CBY09780.1 - 2.3 8.7 5.1 0.33 11.4 0.6 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2312 PF10073.9 CBY09780.1 - 6.7 6.4 6.3 20 4.9 2.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TSP_1 PF00090.19 CBY09781.1 - 1.9e-27 95.2 60.4 1.4e-08 34.8 6.8 5.4 4 0 0 4 4 4 4 Thrombospondin type 1 domain CAP PF00188.26 CBY09781.1 - 3.6e-17 63.4 0.6 1.5e-16 61.4 0.0 2.4 2 0 0 2 2 2 1 Cysteine-rich secretory protein family zf-RING_UBOX PF13445.6 CBY09781.1 - 6.9e-07 29.2 10.5 6.9e-07 29.2 10.5 3.6 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY09781.1 - 1.9e-05 24.5 14.5 1.9e-05 24.5 14.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY09781.1 - 2.9e-05 24.1 15.4 7.5e-05 22.8 13.4 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBY09781.1 - 5.5e-05 22.9 11.7 0.00048 19.9 11.7 2.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY09781.1 - 0.0011 18.8 13.6 0.0011 18.8 13.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY09781.1 - 0.0011 18.9 14.4 0.0011 18.9 14.4 3.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY09781.1 - 0.0052 17.1 13.4 0.0052 17.1 13.4 4.8 4 1 0 4 4 2 1 Ring finger domain Polyoma_coat2 PF00761.20 CBY09781.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein Cwf_Cwc_15 PF04889.12 CBY09781.1 - 0.27 11.0 9.8 0.39 10.4 9.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AMP-binding PF00501.28 CBY09782.1 - 9.1e-102 340.8 0.0 1.2e-101 340.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY09782.1 - 8.3e-17 61.9 0.5 1.6e-16 61.0 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RseA_C PF03873.13 CBY09783.1 - 0.062 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain CRAL_TRIO_2 PF13716.6 CBY09784.1 - 0.0049 17.0 0.4 0.0072 16.5 0.4 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Imm12 PF15560.6 CBY09784.1 - 0.022 14.7 0.2 0.041 13.8 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 12 MttA_Hcf106 PF02416.16 CBY09784.1 - 0.051 12.9 0.4 0.12 11.7 0.4 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family Whirly PF08536.11 CBY09785.1 - 0.092 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Whirly transcription factor O-FucT PF10250.9 CBY09786.1 - 1.2e-07 31.8 0.0 5.5e-06 26.3 0.0 2.7 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase PSI_integrin PF17205.3 CBY09787.1 - 3.4e-07 29.9 9.7 5.1e-07 29.3 9.7 1.3 1 0 0 1 1 1 1 Integrin plexin domain PSI PF01437.25 CBY09787.1 - 8.8e-05 23.0 5.0 0.00013 22.5 5.0 1.2 1 0 0 1 1 1 1 Plexin repeat Integrin_beta PF00362.18 CBY09788.1 - 5.4e-41 140.9 0.0 1.3e-40 139.7 0.0 1.6 2 0 0 2 2 2 1 Integrin beta chain VWA domain EGF_2 PF07974.13 CBY09788.1 - 0.003 17.9 17.0 0.003 17.9 17.0 6.9 6 2 0 6 6 6 4 EGF-like domain I-EGF_1 PF18372.1 CBY09788.1 - 0.015 15.3 10.3 0.015 15.3 10.3 6.3 5 2 0 5 5 5 0 Integrin beta epidermal growth factor like domain 1 Integrin_b_cyt PF08725.11 CBY09788.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain POPLD PF08170.12 CBY09789.1 - 0.014 15.8 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 POPLD (NUC188) domain POP1 PF06978.11 CBY09790.1 - 3e-06 27.4 6.8 3e-06 27.4 6.8 2.1 1 1 1 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 Nbl1_Borealin_N PF10444.9 CBY09790.1 - 0.081 12.6 2.9 0.6 9.8 0.1 2.8 2 2 1 3 3 3 0 Nbl1 / Borealin N terminal PMP22_Claudin PF00822.20 CBY09791.1 - 3.4e-20 72.6 10.7 3.7e-18 65.9 2.7 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY09791.1 - 0.0097 15.7 23.8 0.55 10.0 16.9 3.4 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 CBY09791.1 - 2.8 7.4 9.5 0.092 12.2 0.4 2.5 2 1 1 3 3 3 0 Clc-like DHHC PF01529.20 CBY09792.1 - 5.5e-27 94.5 7.1 5.5e-27 94.5 7.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase PDZ PF00595.24 CBY09793.1 - 0.0075 16.6 0.0 0.86 10.0 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY09793.1 - 0.19 11.6 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 PDZ domain Requiem_N PF14051.6 CBY09794.1 - 1.2e-22 79.8 3.4 2.7e-22 78.8 3.4 1.6 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.29 CBY09794.1 - 7.2e-16 57.8 25.3 2.5e-11 43.3 3.9 3.3 2 2 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 CBY09794.1 - 0.014 15.0 0.4 0.014 15.0 0.4 3.9 5 1 0 5 5 5 0 PHD-finger ubiquitin PF00240.23 CBY09795.1 - 1.9e-16 59.6 0.0 4.4e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 CBY09795.1 - 2.6e-08 33.9 11.6 4.3e-08 33.2 11.6 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 CBY09795.1 - 0.00065 19.5 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Exo84_C PF16528.5 CBY09796.1 - 2.1e-31 109.3 0.7 2.1e-31 109.3 0.7 2.7 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CBY09796.1 - 3.4e-13 49.5 3.2 7.6e-13 48.4 1.8 2.4 2 0 0 2 2 2 1 Vps51/Vps67 PH PF00169.29 CBY09796.1 - 2e-05 25.0 0.0 4.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 PH domain COG2 PF06148.11 CBY09796.1 - 0.0054 16.8 3.0 0.011 15.8 0.2 2.7 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Exotox-A_cataly PF09009.10 CBY09797.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A catalytic RRM_1 PF00076.22 CBY09798.1 - 2.5e-29 100.9 0.1 3e-13 49.4 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY09798.1 - 8.5e-10 38.6 0.1 0.0017 18.5 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CBY09798.1 - 8.7e-06 25.7 0.0 0.079 13.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY09798.1 - 0.018 15.0 0.1 0.17 11.9 0.1 2.3 2 0 0 2 2 2 0 RNA binding motif Dabb PF07876.12 CBY09798.1 - 0.072 13.7 0.1 0.2 12.3 0.1 1.8 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain CDC45 PF02724.14 CBY09798.1 - 0.36 9.1 3.2 0.45 8.7 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ShK PF01549.24 CBY09799.1 - 4.9e-12 46.2 135.9 0.0019 18.7 8.6 11.0 10 1 0 10 10 10 8 ShK domain-like Thyroglobulin_1 PF00086.18 CBY09799.1 - 1.3e-08 34.3 1.9 4.4e-08 32.7 1.9 1.9 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat PhoPQ_related PF10142.9 CBY09800.1 - 1.3e-62 211.6 4.1 1.9e-62 211.0 4.1 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_M14 PF00246.24 CBY09800.1 - 3.7e-22 79.5 0.0 7.1e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Ribosomal_S17_N PF16205.5 CBY09801.1 - 5.1e-29 100.5 1.6 5.1e-29 100.5 1.6 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CBY09801.1 - 9.2e-26 89.7 1.1 9.2e-26 89.7 1.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 PRF PF06875.11 CBY09801.1 - 0.11 11.9 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Ribonuc_red_lgC PF02867.15 CBY09802.1 - 1.4e-180 601.3 0.0 1.7e-180 601.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CBY09802.1 - 2.7e-22 78.5 0.0 5.4e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CBY09802.1 - 2.7e-17 63.1 0.1 1.2e-16 61.1 0.1 2.2 1 0 0 1 1 1 1 ATP cone domain ERCC4 PF02732.15 CBY09803.1 - 1e-15 58.3 0.0 2.5e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain FANCI_S4 PF14678.6 CBY09803.1 - 0.15 11.1 7.2 0.041 13.0 1.8 2.5 3 0 0 3 3 3 0 FANCI solenoid 4 PA28_beta PF02252.18 CBY09803.1 - 0.41 10.3 4.1 1.4 8.6 0.0 3.7 5 0 0 5 5 5 0 Proteasome activator pa28 beta subunit RUN PF02759.19 CBY09804.1 - 3.9e-10 39.8 0.1 3.9e-10 39.8 0.1 3.0 3 1 0 3 3 3 1 RUN domain UPF0242 PF06785.11 CBY09804.1 - 0.0078 16.3 0.7 0.0078 16.3 0.7 3.3 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 CBY09804.1 - 0.016 15.4 6.8 0.016 15.4 6.8 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF1465 PF07323.12 CBY09804.1 - 0.27 11.1 11.9 0.057 13.3 1.6 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1465) DUF1411 PF07199.11 CBY09804.1 - 0.81 9.3 5.5 0.25 11.0 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) ORF6C PF10552.9 CBY09804.1 - 7.8 6.6 9.8 1.1 9.3 0.7 3.2 2 1 0 2 2 2 0 ORF6C domain Ebp2 PF05890.12 CBY09805.1 - 6.6e-61 206.2 24.9 9.9e-61 205.6 24.9 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 VSG_B PF13206.6 CBY09805.1 - 0.019 14.3 9.7 0.032 13.5 9.7 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain Spc7 PF08317.11 CBY09805.1 - 0.74 8.6 14.1 3.9 6.3 11.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein MAGE_N PF12440.8 CBY09805.1 - 1.4 9.7 6.3 2.8 8.7 6.3 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Methyltransf_11 PF08241.12 CBY09806.1 - 3.4e-10 40.5 0.0 5.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY09806.1 - 1.1e-09 38.8 0.0 2.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 CBY09806.1 - 5e-08 33.6 4.9 8.4e-08 32.9 4.9 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_23 PF13489.6 CBY09806.1 - 8.6e-06 25.7 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY09806.1 - 0.00093 19.9 0.0 0.0019 18.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 CBY09806.1 - 0.0053 16.4 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 CBY09806.1 - 0.01 15.6 0.1 0.018 14.9 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CBY09806.1 - 0.018 14.4 0.0 0.054 12.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.13 CBY09806.1 - 0.031 14.6 0.1 0.14 12.5 0.0 2.0 2 1 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.18 CBY09806.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 DNA methylase PCMT PF01135.19 CBY09806.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CBY09806.1 - 0.19 11.7 2.1 0.42 10.6 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase domain RR_TM4-6 PF06459.12 CBY09807.1 - 6.4 6.5 10.9 8.9 6.0 10.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 CBY09807.1 - 8.2 5.2 10.9 11 4.7 10.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain TLE_N PF03920.15 CBY09808.1 - 1.6e-52 177.0 5.2 2.6e-52 176.4 5.2 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 CBY09808.1 - 4.3e-20 71.7 17.6 0.00019 22.1 0.6 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09808.1 - 3.5e-07 30.4 0.1 0.11 12.7 0.0 3.9 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Sec34 PF04136.15 CBY09808.1 - 0.026 14.4 0.3 0.048 13.5 0.3 1.3 1 0 0 1 1 1 0 Sec34-like family RAB3GAP2_N PF14655.6 CBY09808.1 - 0.06 12.6 0.0 0.92 8.7 0.0 2.4 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 CBY09808.1 - 0.13 10.8 0.0 3.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 CBY09808.1 - 0.14 11.4 0.0 12 5.1 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain Dicty_REP PF05086.12 CBY09809.1 - 0.027 12.5 1.3 0.032 12.2 1.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF5435 PF17503.2 CBY09809.1 - 0.14 11.9 2.2 0.2 11.4 1.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5435) Mucin PF01456.17 CBY09809.1 - 4.8 7.2 25.9 8.4 6.4 25.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein BSP_II PF05432.11 CBY09809.1 - 7.4 6.2 12.7 15 5.2 12.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Glyco_hydro_16 PF00722.21 CBY09810.1 - 1.8e-25 89.4 1.1 2.6e-25 88.9 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.25 CBY09811.1 - 6.7e-44 150.2 0.3 9.4e-44 149.8 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY09811.1 - 4.2e-25 88.5 0.0 5.7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 CBY09811.1 - 5.8e-09 36.2 1.1 1.1e-08 35.2 0.3 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A WD40 PF00400.32 CBY09811.1 - 3.6e-05 24.4 0.2 3.6e-05 24.4 0.2 3.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09811.1 - 0.00022 21.4 0.1 0.014 15.7 0.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_fungal PF17667.1 CBY09811.1 - 0.0052 15.6 0.1 0.0084 14.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase zf-CW PF07496.15 CBY09812.1 - 2.3e-14 53.2 3.4 4.2e-14 52.3 3.4 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger PWWP PF00855.17 CBY09812.1 - 6.8e-14 52.1 0.3 2.9e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 PWWP domain AP3D1 PF06375.11 CBY09812.1 - 0.021 15.1 0.9 0.021 15.1 0.9 1.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 zf-C4 PF00105.18 CBY09814.1 - 1e-24 86.7 10.9 2e-24 85.8 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY09814.1 - 2.5e-10 40.3 0.0 9.6e-10 38.4 0.0 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Cadherin_3 PF16184.5 CBY09815.1 - 0.0022 18.0 0.6 1.3 9.1 0.0 3.2 3 0 0 3 3 3 2 Cadherin-like Cadherin_C PF01049.17 CBY09815.1 - 0.0083 16.5 0.0 0.027 14.8 0.0 1.9 1 0 0 1 1 1 1 Cadherin cytoplasmic region 7tm_3 PF00003.22 CBY09815.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Glyco_transf_7C PF02709.14 CBY09816.1 - 1.5e-20 72.7 0.5 3.5e-20 71.4 0.5 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase BAR PF03114.18 CBY09817.1 - 1.1e-13 51.4 2.2 1.6e-13 50.9 2.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 CBY09817.1 - 6.6e-10 38.7 0.2 1.6e-09 37.5 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY09817.1 - 9.4e-07 28.3 0.2 2.6e-06 27.0 0.2 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY09817.1 - 3.1e-05 23.6 0.0 6.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MPS2 PF17060.5 CBY09817.1 - 0.17 11.1 1.9 0.31 10.3 1.9 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 HSBP1 PF06825.12 CBY09817.1 - 4.3 7.3 5.9 3 7.8 0.3 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Galactosyl_T PF01762.21 CBY09818.1 - 7.2e-30 104.3 0.0 1.4e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase zf-C2H2 PF00096.26 CBY09819.1 - 0.2 12.2 8.4 0.25 11.9 0.0 3.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY09819.1 - 0.59 11.1 7.2 0.6 11.1 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Collagen PF01391.18 CBY09820.1 - 6.7e-10 38.6 33.0 4.6e-08 32.7 33.0 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.6 CBY09821.1 - 5.5e-41 138.6 134.1 1.7e-09 37.8 11.7 33.2 11 2 15 26 26 26 8 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY09821.1 - 4.5e-24 84.0 51.4 6.8e-08 32.3 0.2 36.2 36 7 6 42 42 42 10 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY09821.1 - 3.8e-23 81.4 83.9 6.2e-10 39.1 5.8 32.1 19 6 11 30 30 30 6 Calcium-binding EGF domain Laminin_EGF PF00053.24 CBY09821.1 - 2.2e-20 72.5 558.7 0.00026 21.0 15.3 30.7 6 5 24 30 30 30 17 Laminin EGF domain EGF_2 PF07974.13 CBY09821.1 - 0.0003 21.1 39.0 0.00039 20.7 17.7 39.8 29 13 6 35 35 35 11 EGF-like domain EGF PF00008.27 CBY09821.1 - 0.0046 17.2 3.1 0.0046 17.2 3.1 35.3 36 3 0 36 36 36 14 EGF-like domain EGF_3 PF12947.7 CBY09821.1 - 0.01 16.0 10.1 0.01 16.0 10.1 30.6 27 6 3 30 30 30 0 EGF domain hEGF PF12661.7 CBY09821.1 - 0.013 16.1 7.1 0.013 16.1 7.1 36.4 34 5 1 35 35 35 0 Human growth factor-like EGF Dynein_C PF18199.1 CBY09822.1 - 2.9e-94 315.7 1.7 3.3e-94 315.6 0.3 1.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBY09822.1 - 8.7e-88 293.1 0.1 3.8e-87 291.0 0.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 CBY09822.1 - 2.8e-81 273.2 0.8 2.8e-81 273.2 0.8 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CBY09822.1 - 1.3e-51 174.6 0.0 2.8e-51 173.6 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBY09822.1 - 3.3e-40 136.9 0.0 2.9e-38 130.6 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain UPF0242 PF06785.11 CBY09822.1 - 0.45 10.6 4.5 0.19 11.8 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4665 PF15679.5 CBY09822.1 - 0.72 10.5 5.2 0.43 11.2 0.6 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4665) FliJ PF02050.16 CBY09822.1 - 1.4 9.1 11.1 1.3 9.2 3.5 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein Laminin_II PF06009.12 CBY09822.1 - 4 7.4 14.2 0.34 10.9 3.5 3.3 3 0 0 3 3 3 0 Laminin Domain II HBM PF16591.5 CBY09822.1 - 4.4 6.6 10.5 1.1 8.7 5.1 2.2 2 0 0 2 2 2 0 Helical bimodular sensor domain Spc7 PF08317.11 CBY09822.1 - 5.9 5.7 13.1 0.079 11.8 3.2 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_8 PF12780.7 CBY09823.1 - 2.4e-90 302.4 0.0 3.3e-90 301.9 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_lid_1 PF17857.1 CBY09823.1 - 5.8e-36 122.7 0.2 1e-35 121.9 0.2 1.3 1 0 0 1 1 1 1 AAA+ lid domain MT PF12777.7 CBY09823.1 - 1.9e-19 69.9 11.8 2.4e-18 66.3 11.8 2.0 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBY09823.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DHC_N2 PF08393.13 CBY09824.1 - 2.1e-126 422.2 18.0 2.1e-126 422.2 18.0 4.7 4 1 0 4 4 4 2 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CBY09824.1 - 9.3e-101 338.2 7.0 8.9e-64 216.1 1.4 5.2 2 2 2 4 4 4 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CBY09824.1 - 1.2e-59 201.9 0.1 2.6e-59 200.8 0.1 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CBY09824.1 - 0.024 14.6 0.0 0.15 12.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CBY09824.1 - 0.039 14.4 0.0 0.22 12.0 0.0 2.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PPARgamma_N PF12577.8 CBY09824.1 - 0.13 12.9 2.1 30 5.3 0.1 3.3 2 0 0 2 2 2 0 PPAR gamma N-terminal region DUF3896 PF13035.6 CBY09824.1 - 0.14 12.3 1.2 35 4.6 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) DUF3763 PF12592.8 CBY09824.1 - 3 7.9 14.7 5.7 7.1 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3763) DUF2674 PF10879.8 CBY09824.1 - 3.9 7.1 10.3 12 5.6 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2674) Sulfate_transp PF00916.20 CBY09825.1 - 7.4e-45 153.3 3.1 8.8e-45 153.1 3.1 1.0 1 0 0 1 1 1 1 Sulfate permease family Inositol_P PF00459.25 CBY09826.1 - 2.6e-34 119.0 0.0 3.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family LSDAT_euk PF18139.1 CBY09827.1 - 3.5e-34 118.4 0.0 5.6e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CBY09827.1 - 1.3e-16 60.5 0.0 4.5e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote DUF2288 PF10052.9 CBY09827.1 - 0.019 15.0 0.9 0.069 13.2 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Ion_trans PF00520.31 CBY09828.1 - 0.004 16.4 0.2 0.006 15.8 0.2 1.2 1 0 0 1 1 1 1 Ion transport protein 7TM-7TMR_HD PF07698.11 CBY09828.1 - 0.057 13.2 0.5 0.092 12.5 0.5 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Aldo_ket_red PF00248.21 CBY09830.1 - 6.5e-16 58.4 0.0 1.1e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4210 PF13915.6 CBY09830.1 - 0.061 13.9 0.2 0.96 10.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4210) WD40 PF00400.32 CBY09832.1 - 6.7e-14 52.1 9.9 6.5e-06 26.8 0.3 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY09832.1 - 0.00093 18.2 0.7 0.22 10.4 0.1 2.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CBY09832.1 - 0.0014 18.9 0.1 0.68 10.3 0.1 3.7 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Histone PF00125.24 CBY09833.1 - 1.7e-16 60.8 0.2 2e-16 60.5 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY09833.1 - 0.00028 21.1 0.1 0.00047 20.4 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY09833.1 - 0.098 13.2 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY09833.1 - 0.16 12.0 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 YscO-like protein Histone PF00125.24 CBY09834.1 - 1.2e-15 58.0 0.0 1.6e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CBY09834.1 - 6.7e-15 54.5 0.5 6.7e-15 54.5 0.5 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CBY09834.1 - 1.3e-06 28.6 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hormone_recep PF00104.30 CBY09835.1 - 1.3e-38 132.6 0.0 1.9e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CBY09835.1 - 6.9e-31 106.5 16.2 6.9e-31 106.5 16.2 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Xan_ur_permease PF00860.20 CBY09836.1 - 0.21 10.3 5.9 0.44 9.2 5.3 1.7 1 1 1 2 2 2 0 Permease family FeoB_C PF07664.12 CBY09836.1 - 4.5 7.0 7.5 1.8 8.3 0.6 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Tweety PF04906.13 CBY09837.1 - 0.0058 15.3 1.7 0.0077 14.9 1.7 1.3 1 0 0 1 1 1 1 Tweety PLAC8 PF04749.17 CBY09837.1 - 0.044 14.8 9.7 0.078 14.0 9.7 1.6 1 1 0 1 1 1 0 PLAC8 family DUF4131 PF13567.6 CBY09837.1 - 1.3 8.7 3.8 7.9 6.1 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PMP22_Claudin PF00822.20 CBY09838.1 - 1.8e-13 50.7 12.3 2.8e-12 46.8 4.6 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY09838.1 - 0.33 10.7 14.6 1.1e+02 2.5 14.6 2.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SNAP PF14938.6 CBY09839.1 - 2e-39 135.7 12.2 2.9e-39 135.2 12.2 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP FlhC PF05280.11 CBY09839.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Csa1 PF06023.12 CBY09839.1 - 0.072 12.4 0.7 1.2 8.4 0.0 2.2 1 1 1 2 2 2 0 CRISPR-associated exonuclease Csa1 ATP-synt_S1 PF05827.12 CBY09840.1 - 4.1e-15 55.9 0.1 7.9e-15 55.0 0.1 1.5 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.17 CBY09840.1 - 0.0049 16.7 1.1 0.012 15.4 0.8 1.8 2 1 0 2 2 2 1 Lysosome-associated membrane glycoprotein (Lamp) UQ_con PF00179.26 CBY09841.1 - 2.5e-48 163.3 0.1 2.7e-48 163.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY09841.1 - 8.9e-05 22.2 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBY09841.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 CBY09841.1 - 0.004 17.4 0.1 0.0048 17.2 0.1 1.4 1 1 0 1 1 1 1 RWD domain Mob1_phocein PF03637.17 CBY09842.1 - 1.5e-50 171.5 6.1 1.9e-50 171.2 6.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Ras PF00071.22 CBY09843.1 - 5.9e-37 126.8 0.2 6.8e-37 126.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY09843.1 - 2.9e-12 46.9 0.0 4.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY09843.1 - 3.2e-07 30.0 0.0 4.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY09843.1 - 5.4e-06 26.5 0.0 8.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY09843.1 - 0.00013 21.9 0.0 0.12 12.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CBY09843.1 - 0.0043 16.6 0.1 0.0093 15.5 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 CBY09843.1 - 0.0084 16.2 0.1 0.015 15.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 CBY09843.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.29 CBY09843.1 - 0.057 13.9 0.1 9.5 6.7 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AdoHcyase PF05221.17 CBY09845.1 - 1.8e-119 398.3 0.0 1.6e-65 221.2 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CBY09845.1 - 3e-75 251.7 1.5 5.6e-75 250.8 1.5 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CBY09845.1 - 1.4e-08 34.3 0.1 2.5e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBY09845.1 - 9.1e-06 25.3 0.1 1.6e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain OCD_Mu_crystall PF02423.15 CBY09845.1 - 0.012 14.5 0.7 0.029 13.3 0.2 1.7 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family THF_DHG_CYH_C PF02882.19 CBY09845.1 - 0.014 14.8 0.8 0.043 13.1 0.8 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 CBY09845.1 - 0.063 13.5 0.3 0.19 12.0 0.3 1.9 1 1 0 1 1 1 0 TrkA-N domain ACT_7 PF13840.6 CBY09845.1 - 0.1 12.4 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 ACT domain NAD_binding_7 PF13241.6 CBY09845.1 - 0.16 12.4 0.3 0.71 10.3 0.2 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF826 PF05696.11 CBY09846.1 - 0.01 15.9 0.0 0.037 14.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF826) CRF PF00473.17 CBY09846.1 - 0.13 12.4 0.7 0.38 10.8 0.0 2.2 2 0 0 2 2 2 0 Corticotropin-releasing factor family APG6_N PF17675.1 CBY09846.1 - 0.13 12.8 8.1 1.5 9.3 2.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region EBP50_C PF09007.11 CBY09846.1 - 2.9 8.9 12.3 0.81 10.7 7.6 2.2 2 0 0 2 2 2 0 EBP50, C-terminal ABC_tran_Xtn PF12848.7 CBY09846.1 - 4.1 7.5 8.6 13 5.9 8.6 1.9 1 0 0 1 1 1 0 ABC transporter Mito_carr PF00153.27 CBY09847.1 - 1.2e-46 156.5 1.4 1.5e-18 66.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Pou PF00157.17 CBY09848.1 - 2.2e-23 82.0 0.0 5.6e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY09848.1 - 3.1e-07 30.1 0.3 7.5e-07 28.9 0.3 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CBY09848.1 - 0.0041 17.4 0.0 0.17 12.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain LcrR PF09621.10 CBY09848.1 - 0.027 13.9 0.4 0.074 12.5 0.1 1.9 2 1 0 2 2 2 0 Type III secretion system regulator (LcrR) HTH_ABP1_N PF18107.1 CBY09848.1 - 0.048 13.4 2.5 9.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Fission yeast centromere protein N-terminal domain Mo25 PF08569.11 CBY09849.1 - 1.8e-18 67.0 0.1 2.1e-18 66.8 0.1 1.0 1 0 0 1 1 1 1 Mo25-like Mo25 PF08569.11 CBY09850.1 - 2.3e-68 231.0 9.0 3.5e-68 230.4 9.0 1.2 1 0 0 1 1 1 1 Mo25-like Sec16_C PF12931.7 CBY09853.1 - 8.8e-47 160.2 2.4 1.5e-46 159.5 2.4 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CBY09853.1 - 0.039 14.5 0.0 0.099 13.2 0.0 1.7 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Ephrin_rec_like PF07699.13 CBY09854.1 - 1e-07 31.6 29.2 4.1e-05 23.3 6.2 56.7 42 14 17 59 59 59 29 Putative ephrin-receptor like SieB PF14163.6 CBY09854.1 - 4.3 6.8 4.8 21 4.6 0.7 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B UQ_con PF00179.26 CBY09856.1 - 3.1e-45 153.3 0.0 3.8e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY09856.1 - 0.0016 18.1 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBY09856.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 CBY09856.1 - 0.03 14.6 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain RhoGEF PF00621.20 CBY09857.1 - 1.2e-25 90.8 0.1 1.2e-25 90.8 0.1 4.2 4 1 1 5 5 5 1 RhoGEF domain Spectrin PF00435.21 CBY09857.1 - 1.6e-07 31.8 0.2 1.6e-07 31.8 0.2 5.1 4 1 0 4 4 4 1 Spectrin repeat PH_10 PF15411.6 CBY09857.1 - 0.0013 19.0 0.0 0.0048 17.2 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1845 PF08900.11 CBY09857.1 - 0.04 13.7 3.1 0.042 13.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1845) TssO PF17561.2 CBY09857.1 - 0.078 13.1 13.6 0.68 10.0 2.9 3.8 3 0 0 3 3 3 0 Type VI secretion system, TssO P4Ha_N PF08336.11 CBY09857.1 - 0.76 9.8 12.6 2.4 8.2 0.1 3.7 4 0 0 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4349 PF14257.6 CBY09857.1 - 2.2 7.6 5.4 0.73 9.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) RIH_assoc PF08454.11 CBY09857.1 - 3 7.8 7.6 0.62 9.9 0.4 3.2 3 0 0 3 3 3 0 RyR and IP3R Homology associated DUF3232 PF11554.8 CBY09857.1 - 5.1 7.5 6.0 3.9 7.9 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3232) Hexokinase_2 PF03727.16 CBY09858.1 - 4.6e-79 265.2 0.4 1.1e-78 264.0 0.0 1.8 2 1 1 3 3 3 1 Hexokinase Hexokinase_1 PF00349.21 CBY09858.1 - 4.2e-72 242.2 0.1 8.2e-72 241.3 0.1 1.4 1 0 0 1 1 1 1 Hexokinase Ephrin PF00812.17 CBY09859.1 - 1.7e-34 118.8 0.0 2.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Ephrin Sushi PF00084.20 CBY09860.1 - 0.03 14.9 0.3 0.11 13.1 0.3 2.0 1 0 0 1 1 1 0 Sushi repeat (SCR repeat) Astacin PF01400.24 CBY09861.1 - 1.4e-38 132.5 0.0 5.6e-38 130.5 0.0 2.0 1 1 0 2 2 2 1 Astacin (Peptidase family M12A) UPAR_LY6_2 PF16975.5 CBY09861.1 - 0.38 11.0 19.4 0.071 13.3 15.1 2.0 2 0 0 2 2 2 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Peptidase_S28 PF05577.12 CBY09861.1 - 2.4 6.9 10.8 0.094 11.5 5.0 1.5 2 0 0 2 2 2 0 Serine carboxypeptidase S28 7TM_GPCR_Srw PF10324.9 CBY09863.1 - 0.00011 21.6 2.9 0.0079 15.5 0.7 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw STE3 PF02076.15 CBY09863.1 - 0.00025 20.3 4.6 0.00025 20.3 4.6 1.4 2 0 0 2 2 2 1 Pheromone A receptor DUF898 PF05987.13 CBY09863.1 - 0.0034 16.5 1.0 0.005 15.9 1.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Promethin PF16015.5 CBY09863.1 - 0.018 15.0 0.3 0.018 15.0 0.3 1.7 2 0 0 2 2 2 0 Promethin RseC_MucC PF04246.12 CBY09863.1 - 0.26 11.2 1.3 0.43 10.5 1.3 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC zf-C4 PF00105.18 CBY09864.1 - 2.3e-29 101.6 14.8 2.3e-29 101.6 14.8 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY09864.1 - 1.6e-12 47.4 8.9 5.9e-12 45.6 8.9 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TPR_20 PF14561.6 CBY09864.1 - 0.14 12.5 1.6 0.41 11.0 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ets PF00178.22 CBY09865.1 - 1.1e-36 125.1 0.2 1.6e-36 124.6 0.2 1.3 1 0 0 1 1 1 1 Ets-domain MENTAL PF10457.9 CBY09867.1 - 0.024 14.5 0.1 0.037 13.8 0.1 1.3 1 0 0 1 1 1 0 Cholesterol-capturing domain Guanylate_cyc PF00211.20 CBY09869.1 - 4.3e-116 385.0 0.5 4e-60 202.6 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 CBY09869.1 - 2.1e-18 66.7 0.1 2.1e-18 66.7 0.1 2.5 3 0 0 3 3 3 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 CBY09869.1 - 0.00067 20.2 1.2 0.0017 18.9 1.2 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.14 CBY09869.1 - 0.009 15.5 0.3 1.4 8.3 0.1 2.3 2 0 0 2 2 2 2 Heme NO binding associated VWA PF00092.28 CBY09871.1 - 1.5e-12 48.1 1.6 2.6e-12 47.3 1.6 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY09871.1 - 1.7e-09 38.3 0.1 3.8e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.27 CBY09871.1 - 0.0091 16.3 2.4 0.029 14.7 2.4 1.9 1 0 0 1 1 1 1 EGF-like domain SOG2 PF10428.9 CBY09871.1 - 0.25 10.5 10.9 0.37 9.9 10.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-B_box PF00643.24 CBY09873.1 - 0.00012 22.2 7.0 0.00012 22.2 7.0 3.8 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 CBY09873.1 - 0.0011 18.7 10.4 0.0011 18.7 10.4 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY09873.1 - 0.0028 17.6 5.6 0.0028 17.6 5.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger NHL PF01436.21 CBY09873.1 - 0.0083 16.1 0.0 15 5.8 0.0 4.1 4 0 0 4 4 4 1 NHL repeat zf-RING_2 PF13639.6 CBY09873.1 - 0.018 15.4 9.3 0.018 15.4 9.3 4.3 4 0 0 4 4 4 0 Ring finger domain PDDEXK_6 PF04720.12 CBY09873.1 - 0.75 9.7 5.5 0.16 11.9 1.0 1.9 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Helicase_C PF00271.31 CBY09875.1 - 4.1e-12 46.4 0.4 7e-11 42.5 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY09875.1 - 5.2e-12 45.9 1.4 1.2e-11 44.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 CBY09875.1 - 3.4e-07 30.5 0.0 3.4e-07 30.5 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) TUDOR PF00567.24 CBY09875.1 - 8e-05 22.7 0.3 0.00024 21.1 0.1 1.9 2 0 0 2 2 1 1 Tudor domain AAA_22 PF13401.6 CBY09875.1 - 0.00094 19.5 0.9 0.025 14.9 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CBY09875.1 - 0.0015 18.8 0.1 0.0044 17.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CBY09875.1 - 0.0017 18.4 0.4 0.026 14.5 0.4 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 CBY09875.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 CBY09875.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 CBY09875.1 - 0.029 14.8 0.0 0.097 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CBY09875.1 - 0.052 13.4 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ETC_C1_NDUFA4 PF04800.12 CBY09875.1 - 0.13 12.5 2.4 0.33 11.2 2.4 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region AAA_30 PF13604.6 CBY09875.1 - 0.15 11.8 0.3 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBY09875.1 - 0.15 12.6 0.1 0.8 10.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter WD40 PF00400.32 CBY09876.1 - 1.1e-57 190.6 23.4 5.1e-10 39.8 0.3 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY09876.1 - 4.8e-20 71.6 1.8 0.0062 16.8 0.1 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CBY09876.1 - 6.7e-08 31.7 1.2 0.026 13.3 0.1 3.7 1 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 CBY09876.1 - 5.6e-07 28.6 9.3 0.78 8.3 0.1 5.9 1 1 3 6 6 6 4 Nucleoporin Nup120/160 Frtz PF11768.8 CBY09876.1 - 0.0002 19.8 0.1 0.1 10.9 0.0 2.8 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S41_N PF11918.8 CBY09876.1 - 0.043 14.1 1.9 83 3.4 0.0 4.1 4 0 0 4 4 4 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Kin17_mid PF10357.9 CBY09877.1 - 5.7e-41 139.4 0.1 1.5e-40 138.0 0.1 1.8 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CBY09877.1 - 1.5e-15 57.1 1.7 1.5e-15 57.1 1.7 2.1 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 CBY09877.1 - 0.0018 18.6 4.1 0.0039 17.5 4.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type KOW PF00467.29 CBY09877.1 - 0.0027 17.6 0.8 0.0027 17.6 0.8 2.2 2 0 0 2 2 2 1 KOW motif zf-C2H2_jaz PF12171.8 CBY09877.1 - 0.012 15.8 4.6 0.03 14.6 4.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY09877.1 - 0.17 12.2 4.5 0.38 11.1 2.6 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Vta1 PF04652.16 CBY09878.1 - 1.6e-37 128.7 4.6 2.2e-37 128.2 4.6 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 CBY09878.1 - 4.2e-14 52.0 0.4 8.7e-14 50.9 0.4 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain DUF3344 PF11824.8 CBY09878.1 - 0.0061 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3344) NDK PF00334.19 CBY09879.1 - 1e-27 96.8 0.0 1.6e-24 86.4 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase YsaB PF13983.6 CBY09879.1 - 0.083 13.2 0.2 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 YsaB-like lipoprotein Vps26 PF03643.15 CBY09880.1 - 4e-106 354.0 0.7 4.7e-106 353.8 0.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 CBY09880.1 - 0.00071 20.0 0.1 0.036 14.5 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CBY09880.1 - 0.0028 17.7 3.0 8.6 6.4 0.0 3.7 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain SNRNP27 PF08648.12 CBY09881.1 - 2.6e-26 91.4 4.5 2.6e-26 91.4 4.5 2.0 2 1 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins FAM76 PF16046.5 CBY09881.1 - 3.2 7.0 20.9 4 6.7 20.9 1.2 1 0 0 1 1 1 0 FAM76 protein zf-UBR PF02207.20 CBY09882.1 - 8e-18 64.4 8.9 1.2e-17 63.9 8.9 1.2 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) RINGv PF12906.7 CBY09884.1 - 2.9e-14 52.9 8.5 5.8e-14 52.0 8.5 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CBY09884.1 - 0.058 13.7 8.1 0.15 12.4 8.1 1.7 1 0 0 1 1 1 0 Ring finger domain DUF3611 PF12263.8 CBY09885.1 - 0.34 10.8 10.6 0.063 13.2 6.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) Ninjurin PF04923.12 CBY09885.1 - 0.71 9.8 10.6 3.2 7.8 2.5 3.0 1 1 1 2 2 2 0 Ninjurin SUR7 PF06687.12 CBY09885.1 - 3.8 7.1 23.2 0.44 10.1 1.7 3.1 1 1 2 3 3 3 0 SUR7/PalI family DUF3110 PF11360.8 CBY09886.1 - 0.83 9.9 3.3 0.94 9.7 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3110) PI_PP_I PF18363.1 CBY09886.1 - 6.9 6.9 9.1 9.3 6.5 0.6 3.4 3 1 1 4 4 4 0 Phosphoinositide phosphatase insertion domain CUB PF00431.20 CBY09887.1 - 3.6e-11 43.4 0.0 1.1e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 CUB domain DDHD PF02862.17 CBY09887.1 - 0.028 14.6 1.4 0.037 14.2 1.4 1.1 1 0 0 1 1 1 0 DDHD domain SOG2 PF10428.9 CBY09887.1 - 4 6.5 25.5 5 6.2 25.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 CBY09887.1 - 8.8 3.3 10.8 11 3.0 10.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer OCRE PF17780.1 CBY09888.1 - 0.061 13.3 52.0 2.4 8.3 11.4 4.8 1 1 1 2 2 2 0 OCRE domain Meis_PKNOX_N PF16493.5 CBY09889.1 - 4.6e-25 87.8 0.0 9e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 CBY09889.1 - 2.6e-17 62.4 0.5 5.5e-17 61.4 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY09889.1 - 1.9e-07 30.8 0.1 5.2e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 Homeodomain ECSCR PF15820.5 CBY09890.1 - 0.0098 15.7 2.3 0.016 15.0 0.9 2.1 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator RIFIN PF02009.16 CBY09890.1 - 0.016 15.1 0.9 0.027 14.4 0.9 1.3 1 0 0 1 1 1 0 Rifin AA_permease_2 PF13520.6 CBY09890.1 - 0.023 13.5 0.1 0.034 13.0 0.1 1.2 1 0 0 1 1 1 0 Amino acid permease DUF4349 PF14257.6 CBY09890.1 - 0.044 13.2 0.1 0.088 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) FixQ PF05545.11 CBY09890.1 - 0.072 13.1 0.5 0.16 11.9 0.5 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TMEM154 PF15102.6 CBY09890.1 - 0.09 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Arb1 PF09692.10 CBY09890.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Stevor PF17410.2 CBY09890.1 - 0.28 10.7 1.1 0.49 9.9 1.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4330 PF14221.6 CBY09890.1 - 0.48 10.6 3.4 1.2 9.3 0.3 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4330) EGF_CA PF07645.15 CBY09891.1 - 2.1e-73 242.3 383.4 3.5e-09 36.7 8.1 29.4 24 7 3 27 27 27 21 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY09891.1 - 9.2e-24 83.4 83.9 4.2e-08 33.3 10.3 23.4 18 6 4 22 22 22 7 Coagulation Factor Xa inhibitory site VWA PF00092.28 CBY09891.1 - 5.6e-23 82.1 0.2 2.4e-22 80.0 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain cEGF PF12662.7 CBY09891.1 - 6.2e-23 80.4 215.1 2.1e-08 33.9 2.3 24.3 21 3 1 22 22 22 12 Complement Clr-like EGF-like VWA_2 PF13519.6 CBY09891.1 - 4e-09 37.1 0.0 6.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.27 CBY09891.1 - 2e-07 31.2 53.6 5.3e-05 23.4 6.8 28.2 26 3 2 28 28 28 14 EGF-like domain hEGF PF12661.7 CBY09891.1 - 0.0036 17.9 5.6 0.0036 17.9 5.6 28.2 31 1 0 31 31 31 8 Human growth factor-like EGF LIM PF00412.22 CBY09892.1 - 4.2e-20 71.7 29.2 2.9e-11 43.4 8.0 2.6 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CBY09892.1 - 6.1e-16 58.0 0.5 1.1e-15 57.2 0.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY09892.1 - 4.1e-05 23.4 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Myosin_head PF00063.21 CBY09893.1 - 5.7e-222 738.7 1.3 5.7e-222 738.7 1.3 2.3 2 1 1 3 3 3 1 Myosin head (motor domain) Myosin-VI_CBD PF16521.5 CBY09893.1 - 1e-36 124.8 0.0 2.9e-36 123.3 0.0 1.9 1 0 0 1 1 1 1 Myosin VI cargo binding domain IQ PF00612.27 CBY09893.1 - 9.8e-06 24.9 2.1 3.3e-05 23.3 2.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myosin_N PF02736.19 CBY09893.1 - 7.7e-05 22.4 0.3 0.0002 21.1 0.3 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CBY09893.1 - 4.4 7.6 0.0 4.4 7.6 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain EF-hand_6 PF13405.6 CBY09894.1 - 1.8e-13 49.2 0.1 7.5e-07 28.6 0.3 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY09894.1 - 2.7e-12 45.3 0.3 2.4e-06 26.7 0.7 4.3 4 1 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY09894.1 - 5.2e-12 46.0 0.1 5.4e-06 26.8 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY09894.1 - 2.1e-05 23.8 1.7 3.4e-05 23.1 0.4 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBY09894.1 - 0.00059 19.6 1.8 0.38 10.7 0.2 3.6 1 1 2 3 3 3 2 EF-hand domain pair DUF3741 PF12552.8 CBY09894.1 - 0.00069 19.5 1.3 0.0032 17.4 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3741) EF-hand_9 PF14658.6 CBY09894.1 - 0.044 14.1 0.0 0.41 11.0 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain DUF2465 PF10239.9 CBY09894.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) Phospholip_A2_1 PF00068.19 CBY09895.1 - 2.1e-16 60.4 3.1 2.1e-16 60.4 3.1 2.2 2 1 0 2 2 2 1 Phospholipase A2 Glyco_transf_49 PF13896.6 CBY09897.1 - 5e-95 318.6 0.0 6.1e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Opy2 PF09463.10 CBY09897.1 - 0.22 11.9 2.1 0.45 10.9 2.1 1.5 1 0 0 1 1 1 0 Opy2 protein Bap31 PF05529.12 CBY09898.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 Bap31/Bap29 transmembrane region FKBP_C PF00254.28 CBY09900.1 - 1.3e-08 35.0 0.0 3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SAT PF16073.5 CBY09900.1 - 0.053 13.2 0.5 0.19 11.5 0.2 2.0 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis EntA_Immun PF08951.10 CBY09900.1 - 0.25 11.7 2.6 0.38 11.1 0.4 2.4 2 0 0 2 2 2 0 Enterocin A Immunity Ras PF00071.22 CBY09901.1 - 1.5e-56 190.5 0.0 1.7e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY09901.1 - 3e-23 82.3 0.0 4.9e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY09901.1 - 4.4e-09 36.0 0.0 8.4e-09 35.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBY09901.1 - 0.022 14.2 0.0 0.042 13.3 0.0 1.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Helicase_C_2 PF13307.6 CBY09902.1 - 8.4e-50 169.3 0.4 1.1e-48 165.7 0.0 2.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBY09902.1 - 7.4e-46 156.0 0.1 2.4e-45 154.3 0.1 2.0 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 CBY09902.1 - 1.8e-05 24.6 0.0 0.00066 19.5 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CBY09902.1 - 0.00057 19.9 3.8 0.0025 17.8 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HBB PF06777.11 CBY09902.1 - 0.0011 18.7 0.0 0.0035 17.0 0.0 1.9 1 0 0 1 1 1 1 Helical and beta-bridge domain Globin PF00042.22 CBY09902.1 - 0.035 14.7 0.7 0.035 14.7 0.7 2.3 2 0 0 2 2 2 0 Globin AAA_22 PF13401.6 CBY09902.1 - 0.088 13.1 0.3 10 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF4326 PF14216.6 CBY09902.1 - 1.8 9.3 4.8 1.4 9.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4326) CENP-H PF05837.12 CBY09903.1 - 0.015 15.7 9.8 0.041 14.3 3.3 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 CBY09903.1 - 0.021 15.3 15.0 0.046 14.2 5.5 2.6 2 1 0 2 2 2 0 Cell division protein ZapB GAS PF13851.6 CBY09903.1 - 0.17 11.2 13.1 0.17 11.2 9.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2441 PF10386.9 CBY09903.1 - 0.2 11.6 4.0 0.19 11.7 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) DUF3837 PF12939.7 CBY09903.1 - 0.25 11.7 2.5 15 6.0 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3837) FUSC PF04632.12 CBY09903.1 - 0.26 9.8 2.6 0.34 9.4 2.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Med21 PF11221.8 CBY09903.1 - 0.53 10.5 6.5 0.27 11.5 4.4 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF4407 PF14362.6 CBY09903.1 - 0.58 9.4 5.2 0.86 8.9 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF3_N PF09440.10 CBY09903.1 - 0.86 10.0 7.6 0.23 11.9 1.9 2.0 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain YabA PF06156.13 CBY09903.1 - 2.4 8.8 11.5 8.5 7.1 4.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA KxDL PF10241.9 CBY09903.1 - 2.4 8.5 7.2 1.2 9.5 1.6 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein Mg_chelatase_C PF13335.6 CBY09903.1 - 5.3 7.8 9.6 2.1 9.1 4.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Aa_trans PF01490.18 CBY09904.1 - 7.6e-66 222.5 38.2 1e-65 222.1 38.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBY09905.1 - 1e-57 195.7 31.3 1.4e-57 195.3 31.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-CCCH_4 PF18044.1 CBY09905.1 - 0.0038 17.0 0.1 0.0038 17.0 0.1 2.8 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBY09905.1 - 0.031 14.2 15.5 0.38 10.7 0.6 3.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Lep_receptor_Ig PF06328.11 CBY09905.1 - 0.17 11.8 2.8 18 5.4 0.2 3.5 3 0 0 3 3 3 0 Ig-like C2-type domain zf_CCCH_4 PF18345.1 CBY09905.1 - 0.22 11.7 14.8 0.6 10.2 1.1 3.9 3 0 0 3 3 3 0 Zinc finger domain BTB PF00651.31 CBY09906.1 - 9e-09 35.6 0.4 2.5e-08 34.1 0.4 1.8 1 1 0 1 1 1 1 BTB/POZ domain zf-CCCH_4 PF18044.1 CBY09906.1 - 0.0027 17.5 0.1 0.0027 17.5 0.1 2.8 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBY09906.1 - 0.011 15.6 15.5 0.27 11.2 0.6 3.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Neurochondrin PF05536.11 CBY09906.1 - 0.024 13.0 0.0 0.036 12.5 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin Lep_receptor_Ig PF06328.11 CBY09906.1 - 0.051 13.5 2.6 13 5.9 0.2 3.6 3 0 0 3 3 3 0 Ig-like C2-type domain zf_CCCH_4 PF18345.1 CBY09906.1 - 0.11 12.6 14.8 0.43 10.7 1.1 3.6 3 0 0 3 3 3 0 Zinc finger domain UNC-93 PF05978.16 CBY09907.1 - 1e-17 64.3 10.9 1e-17 64.3 10.9 2.1 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CBY09907.1 - 1.1e-05 24.5 42.2 0.0043 16.0 7.0 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF3671 PF12420.8 CBY09907.1 - 0.12 12.4 11.5 0.79 9.8 0.7 3.1 3 1 0 3 3 3 0 Protein of unknown function CSRNP_N PF16019.5 CBY09908.1 - 3e-48 164.6 15.5 6.7e-47 160.2 15.5 2.4 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus Vpu PF00558.19 CBY09908.1 - 1.7 8.5 3.6 3.7 7.4 3.6 1.5 1 0 0 1 1 1 0 Vpu protein Rad54_N PF08658.10 CBY09908.1 - 3.2 7.9 6.2 0.69 10.1 1.8 2.1 1 1 1 2 2 2 0 Rad54 N terminal Peptidase_M73 PF12389.8 CBY09910.1 - 0.042 13.7 0.6 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 Camelysin metallo-endopeptidase Glyco_hydro_9 PF00759.19 CBY09911.1 - 2e-120 403.0 0.0 2.8e-120 402.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Phospholip_A2_1 PF00068.19 CBY09912.1 - 5.8e-06 26.8 0.2 2.3e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Phospholipase A2 7tm_1 PF00001.21 CBY09914.1 - 6.4e-08 32.2 1.9 8.1e-08 31.9 1.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BC10 PF06726.12 CBY09914.1 - 0.041 14.1 0.8 0.1 12.9 0.1 1.9 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 MotA_ExbB PF01618.16 CBY09914.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Ribosomal_L7Ae PF01248.26 CBY09915.1 - 2.4e-22 78.5 0.7 5.2e-22 77.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S10 PF00338.22 CBY09916.1 - 2.6e-11 43.6 0.2 8.5e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e EPL1 PF10513.9 CBY09918.1 - 1.3 9.3 10.5 0.14 12.6 3.2 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Peptidase_C13 PF01650.18 CBY09919.1 - 1.3e-38 133.0 0.1 1.9e-38 132.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 CBY09919.1 - 0.00064 19.7 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain ArgoMid PF16487.5 CBY09919.1 - 0.052 13.8 0.2 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Mid domain of argonaute Med31 PF05669.12 CBY09920.1 - 8.9e-36 121.8 2.3 1.7e-35 120.9 2.3 1.4 1 0 0 1 1 1 1 SOH1 HEAT PF02985.22 CBY09921.1 - 1.3e-30 102.8 11.2 0.0012 18.9 0.0 16.5 18 0 0 18 18 18 7 HEAT repeat HEAT_EZ PF13513.6 CBY09921.1 - 3.1e-23 81.8 15.0 0.026 15.0 0.0 14.0 13 3 2 15 15 15 6 HEAT-like repeat HEAT_2 PF13646.6 CBY09921.1 - 2.2e-20 72.8 20.3 0.0042 17.5 0.0 12.5 10 4 5 15 15 15 10 HEAT repeats CLASP_N PF12348.8 CBY09921.1 - 4.6e-16 59.1 0.1 0.0089 15.6 0.0 6.6 6 1 0 6 6 6 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 CBY09921.1 - 3.3e-14 53.2 1.6 0.14 12.8 0.0 12.0 9 5 5 14 14 14 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CBY09921.1 - 2.2e-11 44.1 7.5 0.25 11.4 0.0 9.4 8 3 1 10 10 10 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBY09921.1 - 1.3e-07 30.6 10.2 1 7.8 0.1 8.3 8 1 1 9 9 9 3 Adaptin N terminal region Arm PF00514.23 CBY09921.1 - 0.04 14.0 3.1 1.2e+02 2.9 0.0 6.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CBY09921.1 - 0.05 13.8 4.8 26 5.1 0.0 6.6 7 1 0 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 CBY09921.1 - 0.1 12.1 1.5 3.8 7.0 0.0 4.2 3 1 1 4 4 4 0 Tti2 family EF-hand_1 PF00036.32 CBY09922.1 - 1e-43 143.6 9.4 4.8e-10 38.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY09922.1 - 5.8e-37 126.0 2.1 4.6e-19 68.6 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY09922.1 - 4.3e-35 119.3 9.8 1.1e-15 57.2 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBY09922.1 - 1.2e-31 105.9 4.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBY09922.1 - 1.1e-27 94.2 6.3 1.2e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBY09922.1 - 5.5e-16 58.7 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBY09922.1 - 1.3e-10 41.2 0.3 3.2e-05 23.8 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY09922.1 - 4.3e-08 33.5 0.0 0.0043 17.3 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBY09922.1 - 1.1e-06 29.4 0.0 0.00045 21.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CBY09922.1 - 1.2e-05 25.2 0.0 0.042 13.9 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CBY09922.1 - 1.8e-05 24.7 0.7 0.00011 22.2 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CBY09922.1 - 0.0005 20.2 4.7 0.076 13.2 0.5 3.0 1 1 2 3 3 3 2 Dockerin type I domain DUF1103 PF06513.11 CBY09922.1 - 0.00059 19.5 1.4 0.00069 19.3 1.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 CBY09922.1 - 0.00077 20.2 0.4 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CBY09922.1 - 0.0011 19.0 0.7 0.46 10.4 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein DUF4497 PF14924.6 CBY09922.1 - 0.0017 18.8 0.0 0.9 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 CBY09922.1 - 0.0025 17.8 0.5 0.59 10.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 CBY09922.1 - 0.0032 17.8 0.7 1.7 9.0 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF5580 PF17743.1 CBY09922.1 - 0.011 14.4 0.0 0.011 14.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Poly_export PF02563.16 CBY09922.1 - 0.012 15.8 0.1 0.61 10.3 0.0 3.0 1 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 CBY09922.1 - 0.013 15.4 0.5 0.78 9.6 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF2267 PF10025.9 CBY09922.1 - 0.025 14.8 0.0 0.099 12.9 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) EF-hand_14 PF17959.1 CBY09922.1 - 0.027 14.8 0.1 9.1 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 CBY09922.1 - 0.049 13.3 0.8 0.22 11.2 0.8 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MotA_activ PF09114.10 CBY09922.1 - 0.06 13.5 0.3 1.1 9.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 CBY09922.1 - 0.075 12.2 0.2 7.5 5.6 0.1 2.4 1 1 0 2 2 2 0 Cache domain SurA_N_3 PF13624.6 CBY09922.1 - 0.077 12.8 0.3 1.1 9.0 0.1 2.0 1 1 1 2 2 2 0 SurA N-terminal domain TetR_C_7 PF14246.6 CBY09922.1 - 0.083 12.9 0.1 7.3 6.7 0.0 2.8 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Spore_III_AB PF09548.10 CBY09922.1 - 0.12 12.5 0.3 0.25 11.4 0.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RuvA_C PF07499.13 CBY09922.1 - 0.13 12.7 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain SapB_1 PF05184.15 CBY09922.1 - 0.24 11.5 1.2 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 CMD PF02627.20 CBY09922.1 - 0.29 11.2 1.1 7.1 6.8 0.0 2.8 2 2 0 3 3 2 0 Carboxymuconolactone decarboxylase family Thyroglobulin_1 PF00086.18 CBY09923.1 - 2.2e-07 30.5 0.7 0.0087 15.7 0.0 2.2 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat PBP1_TM PF14812.6 CBY09924.1 - 0.07 13.5 0.9 0.07 13.5 0.9 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TSP_1 PF00090.19 CBY09925.1 - 2.6e-05 24.3 27.2 0.00014 22.0 10.2 9.7 7 3 1 8 8 8 5 Thrombospondin type 1 domain An_peroxidase PF03098.15 CBY09926.1 - 3.6e-132 441.6 0.0 4.6e-132 441.3 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Nsp1 PF11501.8 CBY09926.1 - 0.18 11.9 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Non structural protein Nsp1 CAP PF00188.26 CBY09927.1 - 3.9e-17 63.3 1.0 9.2e-17 62.1 1.0 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ldl_recept_a PF00057.18 CBY09927.1 - 1.5e-08 34.7 9.4 1.5e-08 34.7 9.4 4.0 3 1 0 3 3 3 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 CBY09927.1 - 6.3e-07 29.5 11.2 6.3e-07 29.5 11.2 3.8 4 0 0 4 4 4 1 Thrombospondin type 1 domain Spc24 PF08286.11 CBY09927.1 - 0.097 12.9 0.6 0.28 11.4 0.6 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 YabA PF06156.13 CBY09927.1 - 0.52 11.0 4.1 2.9 8.6 4.1 2.3 1 1 0 1 1 1 0 Initiation control protein YabA PRKCSH-like PF12999.7 CBY09927.1 - 0.71 9.6 8.8 3.2 7.5 8.8 2.2 1 1 0 1 1 1 0 Glucosidase II beta subunit-like Tryp_inh PF17983.1 CBY09927.1 - 8.1 6.6 8.6 0.53 10.4 1.6 2.8 3 0 0 3 3 3 0 Trypsin inhibitors 1,2 and 3 GST_C_3 PF14497.6 CBY09928.1 - 4.5e-09 36.4 0.0 6.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY09928.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY09928.1 - 0.00073 19.7 0.0 0.0013 18.9 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY09928.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AreA_N PF07573.11 CBY09929.1 - 0.43 11.2 3.5 1.5 9.5 0.0 3.4 3 1 1 4 4 4 0 Nitrogen regulatory protein AreA N terminus EGF PF00008.27 CBY09930.1 - 3.3e-99 324.6 517.2 2.1e-06 27.9 6.1 36.7 36 0 0 36 36 36 30 EGF-like domain hEGF PF12661.7 CBY09930.1 - 5.7e-35 118.7 451.3 0.00039 20.9 8.1 39.4 37 3 0 37 37 37 25 Human growth factor-like EGF Ank_2 PF12796.7 CBY09930.1 - 1.6e-26 92.7 2.7 4.3e-11 43.2 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) EGF_2 PF07974.13 CBY09930.1 - 2.8e-16 59.6 643.7 0.0016 18.8 12.2 38.0 36 2 1 37 37 37 27 EGF-like domain Ank_5 PF13857.6 CBY09930.1 - 1.7e-13 50.5 0.6 0.00025 21.3 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY09930.1 - 6.2e-13 47.7 0.1 0.14 12.8 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat EGF_CA PF07645.15 CBY09930.1 - 1.2e-10 41.3 67.0 3.6e-07 30.3 12.2 37.1 11 8 25 36 36 36 10 Calcium-binding EGF domain Ank_4 PF13637.6 CBY09930.1 - 3.5e-10 40.2 1.0 0.12 13.0 0.1 5.0 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY09930.1 - 1.9e-09 37.5 1.0 1.5 9.4 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat NODP PF07684.12 CBY09930.1 - 0.0002 21.4 1.1 0.002 18.2 0.0 3.5 2 0 0 2 2 2 1 NOTCH protein Galactosyl_T PF01762.21 CBY09931.1 - 1.2e-13 51.4 0.0 1.7e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF2439 PF10382.9 CBY09931.1 - 0.039 14.3 0.1 0.094 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) Fringe PF02434.16 CBY09931.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Fringe-like Neur_chan_LBD PF02931.23 CBY09933.1 - 1.1e-48 165.5 0.1 1.4e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Lig_chan PF00060.26 CBY09934.1 - 5.8e-29 100.8 0.0 1.8e-27 96.0 0.0 2.5 1 1 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CBY09934.1 - 4.5e-20 72.0 0.0 1.4e-19 70.4 0.0 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CBY09934.1 - 3.6e-14 52.7 0.0 1.1e-13 51.1 0.0 1.7 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Ly49 PF08391.10 CBY09934.1 - 0.49 10.8 3.1 4.5 7.7 0.4 2.4 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region RuBisCO_large PF00016.20 CBY09937.1 - 0.028 13.6 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain DDE_Tnp_IS240 PF13610.6 CBY09938.1 - 0.042 14.1 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 DDE domain DUF3188 PF11384.8 CBY09939.1 - 0.27 11.0 0.0 0.5 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) SAM_1 PF00536.30 CBY09940.1 - 0.052 14.0 0.1 0.088 13.3 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TMEM151 PF14857.6 CBY09941.1 - 0.034 13.1 1.3 0.037 13.0 0.6 1.3 1 1 0 1 1 1 0 TMEM151 family HSP20 PF00011.21 CBY09943.1 - 0.0067 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.21 CBY09944.1 - 4.2e-05 23.6 1.0 0.63 10.2 0.1 3.6 2 2 0 2 2 2 2 Hsp20/alpha crystallin family RGS12_usC PF16612.5 CBY09944.1 - 0.045 14.2 0.3 0.13 12.7 0.1 1.7 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 Tropomyosin PF00261.20 CBY09947.1 - 2.1e-27 96.0 29.4 2.5e-27 95.8 29.4 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 CBY09947.1 - 4.3e-12 46.4 31.0 1.8e-11 44.3 31.0 1.9 1 1 0 1 1 1 1 Tropomyosin like TMF_DNA_bd PF12329.8 CBY09947.1 - 0.00016 21.6 29.1 0.0018 18.2 16.8 2.4 2 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding T3SSipB PF16535.5 CBY09947.1 - 0.00064 20.2 14.1 0.0015 19.0 13.7 1.8 1 1 0 1 1 1 1 Type III cell invasion protein SipB Lebercilin PF15619.6 CBY09947.1 - 0.0033 17.1 22.8 0.0042 16.8 22.8 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 CBY09947.1 - 0.0035 17.9 31.6 0.089 13.3 17.4 2.2 1 1 1 2 2 2 1 Apg6 coiled-coil region BRE1 PF08647.11 CBY09947.1 - 0.0042 17.1 6.0 0.0042 17.1 6.0 3.1 1 1 2 3 3 3 2 BRE1 E3 ubiquitin ligase Nsp1_C PF05064.13 CBY09947.1 - 0.0071 16.1 6.7 0.0071 16.1 6.7 2.2 1 1 0 2 2 2 1 Nsp1-like C-terminal region DHR10 PF18595.1 CBY09947.1 - 0.008 16.2 28.7 0.096 12.8 5.9 2.4 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain bZIP_1 PF00170.21 CBY09947.1 - 0.0093 16.0 4.7 0.0093 16.0 4.7 2.9 2 1 0 3 3 2 1 bZIP transcription factor DUF2785 PF10978.8 CBY09947.1 - 0.021 14.6 3.8 1.5 8.6 1.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2785) HrpB7 PF09486.10 CBY09947.1 - 0.024 15.0 15.2 0.075 13.4 15.2 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.6 CBY09947.1 - 0.025 14.0 24.6 0.082 12.2 21.8 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 CBY09947.1 - 0.027 14.9 6.5 0.027 14.9 6.5 3.2 1 1 1 2 2 1 0 Cell division protein ZapB Spc7 PF08317.11 CBY09947.1 - 0.029 13.3 28.1 0.43 9.4 4.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FPP PF05911.11 CBY09947.1 - 0.046 11.9 22.3 0.054 11.7 22.3 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Laminin_II PF06009.12 CBY09947.1 - 0.058 13.4 16.5 1.2 9.2 0.1 2.9 1 1 1 2 2 2 0 Laminin Domain II CCDC144C PF14915.6 CBY09947.1 - 0.071 12.2 22.7 0.12 11.5 20.1 2.0 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region RasGAP_C PF03836.15 CBY09947.1 - 0.072 13.2 10.4 0.1 12.8 9.8 1.7 1 1 0 1 1 1 0 RasGAP C-terminus Mod_r PF07200.13 CBY09947.1 - 0.073 13.2 18.8 0.11 12.6 18.8 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Fez1 PF06818.15 CBY09947.1 - 0.076 13.5 22.4 0.25 11.7 22.3 1.7 1 1 0 1 1 1 0 Fez1 Ufd2P_core PF10408.9 CBY09947.1 - 0.089 11.4 4.8 3.2 6.2 1.9 2.0 2 0 0 2 2 2 0 Ubiquitin elongating factor core Cast PF10174.9 CBY09947.1 - 0.11 10.7 21.5 0.18 10.0 21.5 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ERM PF00769.19 CBY09947.1 - 0.15 11.9 27.6 2.4 7.9 27.7 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4201 PF13870.6 CBY09947.1 - 0.15 11.8 24.3 0.38 10.5 14.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF2009 PF09418.10 CBY09947.1 - 0.19 10.8 4.7 0.19 10.7 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF4472 PF14739.6 CBY09947.1 - 0.2 12.4 19.2 0.98 10.2 6.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) ABC_tran_CTD PF16326.5 CBY09947.1 - 0.2 11.9 27.8 1.6 9.0 3.1 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 CBY09947.1 - 0.24 11.4 28.4 0.11 12.5 12.9 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KxDL PF10241.9 CBY09947.1 - 0.24 11.7 13.7 3.2 8.1 0.8 3.2 2 1 0 2 2 2 0 Uncharacterized conserved protein Leu_zip PF15294.6 CBY09947.1 - 0.25 10.8 22.5 0.43 10.0 22.5 1.4 1 1 0 1 1 1 0 Leucine zipper Laminin_I PF06008.14 CBY09947.1 - 0.28 10.9 23.0 4.9 6.8 23.0 2.0 1 1 0 1 1 1 0 Laminin Domain I YscO PF07321.12 CBY09947.1 - 0.3 11.0 20.6 0.94 9.4 12.6 2.5 1 1 1 2 2 2 0 Type III secretion protein YscO DUF724 PF05266.14 CBY09947.1 - 0.38 10.6 21.6 0.19 11.5 16.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EzrA PF06160.12 CBY09947.1 - 0.38 8.9 23.6 0.27 9.4 19.8 2.2 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 CBY09947.1 - 0.4 10.7 15.4 0.59 10.2 7.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.21 CBY09947.1 - 0.4 10.2 22.3 1.3 8.5 9.2 2.0 1 1 1 2 2 2 0 Intermediate filament protein TMPIT PF07851.13 CBY09947.1 - 0.46 9.7 12.6 0.59 9.3 11.8 1.6 1 1 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 CBY09947.1 - 0.5 9.2 10.1 0.56 9.1 10.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein HCMV_UL139 PF12507.8 CBY09947.1 - 0.51 10.7 5.9 0.59 10.5 0.3 2.3 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF948 PF06103.11 CBY09947.1 - 0.76 10.1 8.8 0.84 9.9 2.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.6 CBY09947.1 - 0.8 10.2 18.7 0.82 10.1 6.6 2.8 1 1 1 2 2 2 0 Snapin/Pallidin DUF5340 PF17275.2 CBY09947.1 - 1.1 9.4 6.4 0.24 11.5 1.5 2.2 2 1 1 3 3 3 0 Family of unknown function (DUF5340) Prominin PF05478.11 CBY09947.1 - 1.2 7.0 9.6 1.2 6.9 9.6 1.0 1 0 0 1 1 1 0 Prominin ATG16 PF08614.11 CBY09947.1 - 1.2 9.3 25.9 0.94 9.7 11.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 CBY09947.1 - 1.2 8.7 21.6 1.3 8.5 9.5 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF745 PF05335.13 CBY09947.1 - 1.3 8.7 13.8 1.6 8.4 12.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) ADIP PF11559.8 CBY09947.1 - 1.4 9.0 23.4 1.8 8.6 9.9 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HOOK PF05622.12 CBY09947.1 - 1.4 6.9 25.1 0.31 9.1 11.5 1.9 1 1 1 2 2 2 0 HOOK protein Cep57_CLD PF14073.6 CBY09947.1 - 1.5 8.8 24.7 4.2 7.3 10.2 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 FlaC_arch PF05377.11 CBY09947.1 - 1.5 9.3 19.2 1.9 8.9 1.5 4.2 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.6 CBY09947.1 - 2 7.0 16.7 2.6 6.6 16.7 1.2 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.8 CBY09947.1 - 2 7.6 21.6 0.35 10.1 11.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 CBY09947.1 - 2.5 8.2 26.5 0.18 11.8 15.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CHIP_TPR_N PF18391.1 CBY09947.1 - 3.6 8.4 21.1 7.1 7.5 16.2 2.7 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DUF4407 PF14362.6 CBY09947.1 - 4.8 6.5 15.2 7.3 5.8 15.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 CBY09947.1 - 5.4 5.7 19.8 11 4.7 19.8 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HMMR_N PF15905.5 CBY09947.1 - 5.6 6.3 26.1 0.46 9.9 14.0 2.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Prefoldin_2 PF01920.20 CBY09947.1 - 5.8 6.9 28.9 3.7 7.6 5.1 4.4 1 1 4 5 5 5 0 Prefoldin subunit DUF1635 PF07795.11 CBY09947.1 - 7.4 6.4 18.3 13 5.6 17.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) DLP_helical PF18709.1 CBY09947.1 - 8.6 5.5 16.0 4.1 6.5 2.0 2.2 1 1 1 2 2 2 0 Dynamin-like helical domain TSNAXIP1_N PF15739.5 CBY09947.1 - 9.1 6.7 21.1 1.4 9.4 8.8 2.9 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus FA_hydroxylase PF04116.13 CBY09948.1 - 5.8e-14 52.6 13.6 6.9e-14 52.3 13.6 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Phospholip_A2_1 PF00068.19 CBY09949.1 - 8.6e-12 45.5 0.5 8.6e-12 45.5 0.5 1.6 2 0 0 2 2 2 1 Phospholipase A2 C2 PF00168.30 CBY09951.1 - 1.3e-20 73.6 0.1 3.1e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain DUF1041 PF06292.17 CBY09951.1 - 3.4e-20 72.4 0.2 3.4e-20 72.4 0.2 3.4 3 1 1 4 4 4 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 CBY09951.1 - 1.5e-10 40.8 6.5 1.5e-10 40.8 6.5 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HTH_Mga PF08280.11 CBY09951.1 - 0.036 14.1 0.1 0.84 9.7 0.0 2.8 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain TPR_18 PF13512.6 CBY09951.1 - 0.066 13.3 1.3 0.21 11.7 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PLAT PF01477.23 CBY09954.1 - 1.1e-20 74.4 1.2 2.1e-20 73.4 0.3 1.9 2 0 0 2 2 2 1 PLAT/LH2 domain GPS PF01825.21 CBY09954.1 - 0.047 14.2 0.2 0.1 13.2 0.2 1.5 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif DUF983 PF06170.12 CBY09954.1 - 0.15 12.5 4.4 0.47 10.9 4.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF983) DUF4271 PF14093.6 CBY09954.1 - 0.43 10.5 10.1 0.056 13.4 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Choline_kinase PF01633.20 CBY09955.1 - 4.9e-07 29.6 0.1 6.3e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY09955.1 - 6.2e-05 23.0 0.1 7.8e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY09955.1 - 0.0046 16.3 0.7 0.006 15.9 0.7 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase ABC2_membrane PF01061.24 CBY09956.1 - 1.1e-39 136.1 26.3 1.1e-39 136.1 26.3 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CBY09956.1 - 4.9e-23 82.2 0.0 9.2e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CBY09956.1 - 2.4e-05 24.3 0.1 4.6e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CBY09956.1 - 6.3e-05 22.9 0.0 0.01 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CBY09956.1 - 0.0038 16.8 0.0 0.0085 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBY09956.1 - 0.0099 16.0 0.7 0.028 14.5 0.7 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 CBY09956.1 - 0.012 15.1 0.2 0.089 12.2 0.2 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBY09956.1 - 0.012 15.4 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CBY09956.1 - 0.012 16.1 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CBY09956.1 - 0.022 14.8 0.9 0.18 11.9 0.6 2.4 2 1 0 2 2 2 0 Dynamin family DUF87 PF01935.17 CBY09956.1 - 0.04 14.0 0.6 0.098 12.7 0.6 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 CBY09956.1 - 0.05 13.9 0.0 0.62 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 CBY09956.1 - 5.2 6.3 10.6 12 5.1 9.5 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 CBY09956.1 - 9.4 5.2 27.6 34 3.4 27.5 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Clathrin_lg_ch PF01086.17 CBY09957.1 - 1.1e-35 123.8 10.6 1.3e-35 123.5 10.6 1.0 1 0 0 1 1 1 1 Clathrin light chain Phage_Mu_Gam PF07352.12 CBY09957.1 - 0.41 10.6 8.0 0.61 10.0 7.9 1.5 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein UCH_C PF18031.1 CBY09957.1 - 1.5 8.8 7.0 1.3 9.0 2.2 2.4 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases Ank_2 PF12796.7 CBY09958.1 - 1.7e-05 25.3 0.0 0.0045 17.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY09958.1 - 0.031 14.6 0.0 1.5 9.2 0.0 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 CBY09958.1 - 0.053 14.0 0.0 1.9 9.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat LOH1CR12 PF10158.9 CBY09961.1 - 0.027 14.5 2.5 0.031 14.3 2.3 1.3 1 1 0 1 1 1 0 Tumour suppressor protein ESP PF16590.5 CBY09961.1 - 0.21 11.8 2.1 0.26 11.6 1.4 1.6 1 1 0 1 1 1 0 Exocrine gland-secreting peptide ATP-synt PF00231.19 CBY09962.1 - 6.2e-68 229.5 3.6 7.1e-68 229.3 3.6 1.0 1 0 0 1 1 1 1 ATP synthase Chlorophyllase2 PF12740.7 CBY09963.1 - 0.12 11.2 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Chlorophyllase enzyme Tubulin_3 PF14881.6 CBY09964.1 - 0.004 16.9 0.2 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Tubulin PF00091.25 CBY09964.1 - 0.059 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Sec23_trunk PF04811.15 CBY09965.1 - 1.2e-63 214.9 0.0 1.9e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CBY09965.1 - 1.8e-29 102.3 0.2 2.5e-28 98.7 0.1 2.7 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CBY09965.1 - 1.9e-21 75.8 0.1 8.9e-21 73.7 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CBY09965.1 - 1.8e-15 56.7 8.3 3.6e-15 55.7 8.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CBY09965.1 - 1e-11 44.5 0.2 2.8e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat PIP5K PF01504.18 CBY09966.1 - 7.5e-83 277.9 0.0 1.1e-82 277.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PHD PF00628.29 CBY09967.1 - 1.9e-08 34.1 12.7 3.3e-08 33.3 12.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY09967.1 - 5.4e-05 22.7 6.9 0.00012 21.6 6.9 1.6 1 1 0 1 1 1 1 PHD-finger RAG2_PHD PF13341.6 CBY09967.1 - 0.0049 16.9 0.5 0.0086 16.1 0.5 1.3 1 0 0 1 1 1 1 RAG2 PHD domain DNA_pol3_a_NII PF11490.8 CBY09967.1 - 0.028 14.3 0.5 0.028 14.3 0.5 2.0 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II BUD22 PF09073.10 CBY09967.1 - 0.078 12.3 25.9 0.12 11.7 25.9 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 CBY09967.1 - 0.48 10.1 25.7 0.83 9.3 25.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 CBY09967.1 - 0.68 8.0 18.8 0.97 7.5 18.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 CBY09967.1 - 6.5 5.4 12.0 8.3 5.1 12.0 1.2 1 0 0 1 1 1 0 Presenilin ZapB PF06005.12 CBY09968.1 - 0.0094 16.4 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Cell division protein ZapB APC_N_CC PF16689.5 CBY09968.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain HALZ PF02183.18 CBY09968.1 - 0.016 15.4 0.5 0.028 14.6 0.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 CBY09968.1 - 0.025 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator YscO PF07321.12 CBY09968.1 - 0.052 13.5 0.1 0.068 13.1 0.1 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO CCDC144C PF14915.6 CBY09968.1 - 0.054 12.6 0.0 0.056 12.6 0.0 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region LPP PF04728.13 CBY09968.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper PIP5K PF01504.18 CBY09970.1 - 7.5e-83 277.9 0.0 1.1e-82 277.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PHD PF00628.29 CBY09971.1 - 1.9e-08 34.1 12.7 3.3e-08 33.3 12.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY09971.1 - 5.3e-05 22.7 6.9 0.00012 21.6 6.9 1.6 1 1 0 1 1 1 1 PHD-finger RAG2_PHD PF13341.6 CBY09971.1 - 0.0039 17.2 0.6 0.0067 16.5 0.6 1.3 1 0 0 1 1 1 1 RAG2 PHD domain DNA_pol3_a_NII PF11490.8 CBY09971.1 - 0.0091 15.9 0.6 0.0091 15.9 0.6 2.1 3 0 0 3 3 3 1 DNA polymerase III polC-type N-terminus II BUD22 PF09073.10 CBY09971.1 - 0.11 11.8 25.9 0.047 13.0 23.9 1.3 2 0 0 2 2 2 0 BUD22 DNA_pol_phi PF04931.13 CBY09971.1 - 1.3 7.0 18.3 2 6.4 18.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 CBY09971.1 - 8.5 6.0 29.9 4.7 6.9 27.9 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ZapB PF06005.12 CBY09972.1 - 0.0055 17.1 0.1 0.0086 16.5 0.1 1.3 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 CBY09972.1 - 0.0093 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Septum formation initiator CCDC144C PF14915.6 CBY09972.1 - 0.01 15.0 0.0 0.011 14.9 0.0 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region APC_N_CC PF16689.5 CBY09972.1 - 0.012 15.6 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain HALZ PF02183.18 CBY09972.1 - 0.017 15.3 0.5 0.032 14.5 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4200 PF13863.6 CBY09972.1 - 0.032 14.6 0.1 0.043 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.20 CBY09972.1 - 0.043 13.8 0.3 0.059 13.3 0.3 1.2 1 0 0 1 1 1 0 Prefoldin subunit YscO PF07321.12 CBY09972.1 - 0.046 13.7 0.2 0.061 13.3 0.2 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO Spc24 PF08286.11 CBY09972.1 - 0.064 13.5 0.1 0.075 13.3 0.1 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 HMMR_C PF15908.5 CBY09972.1 - 0.069 13.4 0.0 0.073 13.3 0.0 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal LPP PF04728.13 CBY09972.1 - 0.094 13.1 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper SR-25 PF10500.9 CBY09973.1 - 0.53 9.9 14.4 0.77 9.3 14.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.7 CBY09973.1 - 1.1 7.3 7.0 1.4 7.0 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LSM PF01423.22 CBY09974.1 - 2.9e-06 26.9 0.0 3.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF5569 PF17729.1 CBY09974.1 - 0.069 13.0 0.0 0.071 13.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5569) EF-hand_5 PF13202.6 CBY09976.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 CBY09976.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 CBY09977.1 - 1.5e-11 44.6 2.2 1.9e-11 44.2 2.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY09977.1 - 4e-11 41.9 1.9 0.00015 21.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY09977.1 - 8.1e-10 37.5 1.9 0.0001 21.6 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_11 PF08976.11 CBY09977.1 - 9e-07 29.7 0.0 1e-06 29.5 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 CBY09977.1 - 1.8e-06 27.7 2.7 4.2e-06 26.5 0.4 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY09977.1 - 0.00024 20.5 3.6 0.017 14.6 0.2 2.4 2 0 0 2 2 2 2 EF hand Dockerin_1 PF00404.18 CBY09977.1 - 0.0042 17.2 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 Dockerin type I domain DUF3134 PF11332.8 CBY09977.1 - 0.098 13.0 0.7 0.64 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3134) Skp1 PF01466.19 CBY09978.1 - 0.73 10.0 3.8 0.29 11.3 0.3 2.1 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Piwi PF02171.17 CBY09979.1 - 8e-62 209.2 1.7 1.6e-61 208.2 1.7 1.5 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 CBY09979.1 - 8.5e-06 26.0 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain DUF883 PF05957.13 CBY09979.1 - 0.58 10.8 1.8 1.3 9.7 0.0 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.16 CBY09980.1 - 4.2e-10 39.1 67.4 4e-07 29.3 17.6 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily UNC-93 PF05978.16 CBY09980.1 - 7.4e-07 29.0 7.9 7.4e-07 29.0 7.9 3.1 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 EF-hand_1 PF00036.32 CBY09981.1 - 6.9e-09 34.6 2.8 0.0007 19.0 0.8 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY09981.1 - 3.9e-08 32.6 0.2 0.0018 18.1 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBY09981.1 - 6.7e-08 32.9 1.5 1.6e-07 31.6 0.3 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY09981.1 - 0.00062 19.6 1.0 0.024 14.5 0.3 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_11 PF08976.11 CBY09981.1 - 0.02 15.8 0.1 0.041 14.8 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain Sigma70_r1_1 PF03979.14 CBY09981.1 - 0.067 13.3 0.0 0.24 11.5 0.0 2.0 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 DUF4771 PF15995.5 CBY09981.1 - 0.07 13.4 2.5 0.071 13.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) EF-hand_5 PF13202.6 CBY09981.1 - 0.14 11.7 0.6 3 7.5 0.0 2.5 2 0 0 2 2 2 0 EF hand DHC_N1 PF08385.12 CBY09982.1 - 2.4e-132 442.4 12.4 5.3e-80 269.7 6.2 2.7 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 Cluap1 PF10234.9 CBY09982.1 - 0.0037 16.7 0.5 0.0037 16.7 0.5 2.9 2 1 0 2 2 2 1 Clusterin-associated protein-1 SpoIIIAH PF12685.7 CBY09982.1 - 0.88 9.4 10.9 2.1 8.1 10.9 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF948 PF06103.11 CBY09982.1 - 2 8.8 5.5 48 4.3 0.0 4.4 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1798 PF08807.10 CBY09982.1 - 2 8.6 11.6 0.32 11.2 0.2 4.2 5 0 0 5 5 5 0 Bacterial domain of unknown function (DUF1798) Bacillus_HBL PF05791.11 CBY09982.1 - 2.2 8.1 5.6 10 5.9 0.1 4.2 5 0 0 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) AAA_6 PF12774.7 CBY09983.1 - 1.6e-112 375.7 3.1 4.1e-78 262.6 0.0 3.3 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CBY09983.1 - 1.3e-98 329.5 0.0 2.5e-98 328.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 CBY09983.1 - 5.7e-89 299.0 10.8 1.8e-69 234.8 3.4 4.0 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBY09983.1 - 1.8e-87 293.5 0.1 3.8e-87 292.4 0.1 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CBY09983.1 - 7.1e-53 178.8 1.4 2.4e-46 157.5 0.0 4.0 3 1 1 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBY09983.1 - 7.4e-52 175.5 0.1 1.6e-51 174.3 0.1 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_9 PF12781.7 CBY09983.1 - 6.1e-39 133.4 4.8 3.1e-37 127.8 0.1 4.1 4 1 0 4 4 4 1 ATP-binding dynein motor region MT PF12777.7 CBY09983.1 - 1.4e-26 93.4 2.1 6.7e-25 87.8 0.2 2.3 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 CBY09983.1 - 4.5e-20 71.7 0.0 1.9e-19 69.7 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain Dynein_heavy PF03028.15 CBY09983.1 - 6.4e-20 71.4 0.0 2.2e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CBY09983.1 - 5.4e-11 42.6 0.4 0.014 15.4 0.0 4.8 4 1 1 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CBY09983.1 - 1.1e-05 25.9 0.0 0.035 14.5 0.0 3.5 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 CBY09983.1 - 0.00011 22.3 0.0 0.0024 18.0 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Sec8_exocyst PF04048.14 CBY09983.1 - 0.0013 18.6 2.8 0.0013 18.6 0.5 2.3 2 0 0 2 2 1 1 Sec8 exocyst complex component specific domain AAA_18 PF13238.6 CBY09983.1 - 0.0061 17.1 1.5 0.49 11.0 0.2 3.3 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 CBY09983.1 - 0.1 13.0 0.1 24 5.3 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain COG2 PF06148.11 CBY09983.1 - 0.14 12.2 3.4 0.24 11.5 0.9 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4201 PF13870.6 CBY09983.1 - 0.17 11.6 8.1 0.085 12.6 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 CBY09983.1 - 0.17 12.4 12.4 1.3 9.5 12.4 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region PCRF PF03462.18 CBY09983.1 - 1.2 8.9 4.5 0.47 10.3 1.0 2.1 2 0 0 2 2 1 0 PCRF domain AAA_13 PF13166.6 CBY09983.1 - 1.3 7.6 4.9 2.1 6.9 4.9 1.2 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 CBY09983.1 - 2 8.6 7.5 0.5 10.6 3.8 1.8 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) YscO-like PF16789.5 CBY09983.1 - 3 7.8 9.8 2.3 8.3 6.4 2.6 3 0 0 3 3 2 0 YscO-like protein CENP-Q PF13094.6 CBY09983.1 - 4.1 7.6 6.0 40 4.3 2.9 2.9 3 0 0 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PRC2_HTH_1 PF18118.1 CBY09984.1 - 0.045 14.6 5.0 0.036 14.9 3.9 1.5 1 1 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain CTNNB1_binding PF08347.11 CBY09984.1 - 0.22 11.7 2.4 0.26 11.4 2.4 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Herpes_DNAp_acc PF04929.12 CBY09984.1 - 1.5 7.8 7.1 1.5 7.7 7.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor AAA_23 PF13476.6 CBY09984.1 - 7.2 7.0 13.2 1.6 9.2 10.1 1.5 2 0 0 2 2 2 0 AAA domain Pur_DNA_glyco PF02245.16 CBY09986.1 - 9e-28 96.9 0.0 1.3e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) ATP11 PF06644.11 CBY09986.1 - 2.9 7.6 8.2 4.7 6.9 8.2 1.2 1 0 0 1 1 1 0 ATP11 protein TMEM214 PF10151.9 CBY09986.1 - 7.6 4.9 6.4 11 4.3 6.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator UBD PF16455.5 CBY09987.1 - 9.3e-30 103.0 0.4 3.4e-29 101.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-binding domain ubiquitin PF00240.23 CBY09987.1 - 1.1e-10 41.1 0.1 2.1e-10 40.2 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY09987.1 - 0.0028 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Peptidase_C1 PF00112.23 CBY09988.1 - 7.8e-66 222.3 6.8 9.5e-66 222.0 6.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 CBY09988.1 - 6e-11 42.1 0.0 1.9e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 CBY09988.1 - 0.17 10.6 2.6 2.8 6.6 0.6 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Rab5ip PF07019.12 CBY09989.1 - 1.5e-16 60.7 13.1 1.9e-16 60.4 13.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) UCH PF00443.29 CBY09990.1 - 1.2e-35 123.3 0.0 1.7e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY09990.1 - 2.8e-12 46.9 0.5 1.7e-10 41.0 0.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CBY09990.1 - 2.2e-06 27.3 0.0 5.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 CBY09990.1 - 0.00029 20.4 0.2 0.027 14.0 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Syja_N PF02383.18 CBY09991.1 - 1.4e-87 294.1 1.8 1.4e-87 294.1 1.8 1.5 2 0 0 2 2 2 1 SacI homology domain HSBP1 PF06825.12 CBY09992.1 - 2.2e-20 72.2 11.7 2.7e-20 72.0 11.7 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 CBY09992.1 - 0.013 15.8 0.3 0.023 15.1 0.1 1.4 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 CBY09992.1 - 0.031 14.3 1.2 0.037 14.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DASH_Dad2 PF08654.10 CBY09992.1 - 0.16 12.4 2.5 1.9 8.9 2.9 1.9 1 1 1 2 2 2 0 DASH complex subunit Dad2 CLAMP PF14769.6 CBY09993.1 - 1.7e-27 95.7 1.8 1.7e-27 95.7 1.8 1.5 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 ApoO PF09769.9 CBY09993.1 - 0.09 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein O RabGAP-TBC PF00566.18 CBY09995.1 - 6.7e-12 45.5 1.2 8.2e-12 45.2 1.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 CBY09996.1 - 0.00082 20.1 0.1 0.41 11.6 0.0 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CBY09996.1 - 0.002 16.9 0.0 0.63 8.7 0.0 2.2 1 1 1 2 2 2 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 CBY09996.1 - 0.019 15.3 0.1 3.3 8.1 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY09996.1 - 0.095 11.6 0.1 0.62 9.0 0.0 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 CBY09996.1 - 0.13 11.4 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Dpoe2NT PF12213.8 CBY09997.1 - 1.1e-11 44.9 0.1 1.9e-10 40.9 0.1 2.3 2 0 0 2 2 2 1 DNA polymerases epsilon N terminal BOF PF04076.13 CBY09997.1 - 0.011 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein Birna_RdRp PF04197.12 CBY09997.1 - 0.11 10.8 0.4 0.13 10.6 0.4 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Pox_VLTF3 PF04947.14 CBY09997.1 - 0.21 11.3 1.1 9.5 5.9 0.0 2.6 2 1 1 3 3 3 0 Poxvirus Late Transcription Factor VLTF3 like PAP2 PF01569.21 CBY09998.1 - 1.4e-16 60.5 10.0 2.8e-16 59.5 8.8 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF2681 PF10883.8 CBY09998.1 - 0.19 12.1 2.0 0.5 10.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Ceramidase PF05875.12 CBY09998.1 - 0.39 10.1 5.7 0.22 10.9 2.9 1.7 1 1 1 2 2 2 0 Ceramidase PAP2_C PF14360.6 CBY09998.1 - 1.8 9.2 8.5 1.8 9.1 4.4 2.2 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF4131 PF13567.6 CBY09998.1 - 1.9 8.1 6.0 2.9 7.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AAA PF00004.29 CBY09999.1 - 5.5e-51 172.4 0.0 9.1e-40 136.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY09999.1 - 1.3e-10 40.9 0.1 3.6e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CBY09999.1 - 3.8e-08 33.7 0.5 0.013 15.7 0.0 3.9 2 2 2 4 4 4 2 AAA domain NACHT PF05729.12 CBY09999.1 - 1.8e-07 31.2 0.3 0.017 15.0 0.1 3.4 2 2 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 CBY09999.1 - 2e-06 28.1 0.0 0.016 15.6 0.0 3.6 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 CBY09999.1 - 2.3e-06 28.1 0.2 0.0051 17.2 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CBY09999.1 - 3.8e-06 26.7 0.2 0.0095 15.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CBY09999.1 - 4.1e-06 27.0 0.0 0.00014 22.0 0.0 3.0 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CBY09999.1 - 1.2e-05 24.8 0.3 0.00093 18.6 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY09999.1 - 4.7e-05 23.4 0.6 0.0075 16.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 CBY09999.1 - 0.00013 21.9 0.1 0.17 11.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CBY09999.1 - 0.00023 21.7 0.0 0.34 11.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 CBY09999.1 - 0.00027 21.1 0.0 0.3 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CBY09999.1 - 0.00064 20.3 0.0 0.045 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBY09999.1 - 0.0009 18.5 0.1 0.098 11.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 CBY09999.1 - 0.00091 19.3 0.0 1.4 9.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 CBY09999.1 - 0.001 18.4 0.6 0.23 10.7 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin IstB_IS21 PF01695.17 CBY09999.1 - 0.0021 17.8 0.2 0.65 9.7 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 CBY09999.1 - 0.0026 17.5 0.1 2.9 7.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 CBY09999.1 - 0.0031 16.7 0.1 0.25 10.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ATPase PF06745.13 CBY09999.1 - 0.0037 16.7 0.9 0.031 13.6 0.0 2.6 3 0 0 3 3 2 1 KaiC AAA_25 PF13481.6 CBY09999.1 - 0.0045 16.6 4.7 3.7 7.1 0.1 3.9 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 CBY09999.1 - 0.0046 16.7 0.0 0.2 11.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CBY09999.1 - 0.0078 16.2 0.1 1.3 8.8 0.0 3.3 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CBY09999.1 - 0.0097 15.4 0.0 0.45 10.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 CBY09999.1 - 0.01 16.1 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CBY09999.1 - 0.013 15.3 0.0 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 CBY09999.1 - 0.018 15.5 0.1 1.7 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBY09999.1 - 0.021 14.0 0.6 1.7 7.7 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.15 CBY09999.1 - 0.023 14.7 1.0 6 6.8 0.1 3.3 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit AAA_10 PF12846.7 CBY09999.1 - 0.025 13.5 0.1 0.25 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain CDC48_2 PF02933.17 CBY09999.1 - 0.038 13.8 0.1 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Rad17 PF03215.15 CBY09999.1 - 0.06 13.3 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_3 PF07726.11 CBY09999.1 - 0.096 12.5 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 CBY09999.1 - 0.12 12.6 0.0 0.39 10.9 0.0 2.0 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain ATP_bind_1 PF03029.17 CBY09999.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DNA_pol3_delta2 PF13177.6 CBY09999.1 - 0.14 11.9 0.2 18 5.1 0.2 2.9 2 1 1 3 3 3 0 DNA polymerase III, delta subunit DUF2075 PF09848.9 CBY09999.1 - 0.15 11.2 0.0 7.3 5.7 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 CBY09999.1 - 0.16 11.4 0.1 17 4.7 0.0 3.3 2 1 1 3 3 3 0 Bacterial TniB protein PhoH PF02562.16 CBY09999.1 - 0.2 11.1 0.4 22 4.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.6 CBY09999.1 - 0.33 10.7 2.1 4.2 7.2 0.4 2.9 2 1 0 2 2 2 0 P-loop containing region of AAA domain UBX PF00789.20 CBY10001.1 - 1.6e-08 34.6 0.0 3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain YscO PF07321.12 CBY10001.1 - 0.038 14.0 2.9 0.059 13.3 2.9 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO IFP_35_N PF07334.13 CBY10001.1 - 2.9 8.0 6.9 2.2 8.4 0.2 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus zf-C3HC4_3 PF13920.6 CBY10002.1 - 0.016 15.1 7.5 0.016 15.1 7.5 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 CBY10002.1 - 0.018 15.7 2.5 0.018 15.7 2.5 2.7 3 1 0 3 3 3 0 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 CBY10002.1 - 0.03 14.2 7.3 0.03 14.2 7.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Trypsin PF00089.26 CBY10003.1 - 4.7e-25 88.7 0.0 5.7e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CBY10004.1 - 3e-07 30.5 0.2 3.1e-07 30.4 0.2 1.0 1 0 0 1 1 1 1 Trypsin PsiF_repeat PF07769.14 CBY10004.1 - 0.074 13.0 0.4 0.11 12.4 0.4 1.4 1 1 0 1 1 1 0 psiF repeat ubiquitin PF00240.23 CBY10005.1 - 0.031 14.0 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin family DUF4732 PF15876.5 CBY10006.1 - 6.5e-12 45.8 0.0 7.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4732) Toxin-deaminase PF14424.6 CBY10006.1 - 0.1 12.7 0.5 0.15 12.2 0.5 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Y_phosphatase PF00102.27 CBY10007.1 - 4.7e-147 487.8 0.1 6.3e-77 258.3 0.0 2.6 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 CBY10007.1 - 1.3e-09 37.9 0.0 0.00016 21.5 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBY10007.1 - 7.9e-08 32.6 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBY10007.1 - 0.00023 21.3 0.0 0.27 11.3 0.0 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate Rad21_Rec8_N PF04825.13 CBY10010.1 - 2.9e-08 33.8 0.5 8e-08 32.4 0.1 1.8 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CBY10010.1 - 4e-06 26.0 0.0 1.2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 CBY10010.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Segregation and condensation protein ScpA SIX1_SD PF16878.5 CBY10012.1 - 2.9e-42 143.7 0.8 8.1e-42 142.2 0.3 1.9 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CBY10012.1 - 1e-13 50.9 1.8 1.6e-13 50.3 0.6 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY10012.1 - 1.2e-11 44.3 0.7 2.6e-11 43.3 0.7 1.6 1 0 0 1 1 1 1 Homeobox KN domain FANCI_S1-cap PF14674.6 CBY10012.1 - 0.017 15.2 0.8 0.081 13.0 0.1 2.5 3 0 0 3 3 3 0 FANCI solenoid 1 cap HTH_3 PF01381.22 CBY10012.1 - 0.036 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.8 CBY10012.1 - 0.11 12.0 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-rbx1 PF12678.7 CBY10013.1 - 1.9e-18 66.5 14.5 3e-18 65.9 14.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY10013.1 - 1.1e-15 57.4 15.4 1.6e-15 56.9 15.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBY10013.1 - 0.00081 19.7 22.3 0.02 15.2 22.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY10013.1 - 0.03 14.2 14.8 0.095 12.6 14.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY10013.1 - 0.13 12.2 17.7 0.066 13.1 12.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY10013.1 - 5.4 6.9 18.3 96 3.0 18.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 CBY10014.1 - 5.2e-40 137.6 0.1 1.3e-39 136.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY10014.1 - 5.6e-07 29.5 5.9 1.7e-05 24.6 0.0 3.2 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase MTS PF05175.14 CBY10015.1 - 1.7e-09 37.4 0.0 2.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CBY10015.1 - 3.8e-08 33.1 0.1 5.4e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CBY10015.1 - 4e-08 33.2 0.1 5.1e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CBY10015.1 - 5.6e-08 32.6 0.0 7.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CBY10015.1 - 4.2e-06 27.4 0.1 7.6e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY10015.1 - 0.00025 21.6 0.0 0.00046 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CBY10015.1 - 0.0016 18.1 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 CBY10015.1 - 0.029 13.7 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase DOT1 PF08123.13 CBY10015.1 - 0.03 13.8 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PDEase_I_N PF08499.12 CBY10015.1 - 0.084 12.7 0.3 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Methyltransf_32 PF13679.6 CBY10015.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 CBY10015.1 - 0.17 10.9 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FBPase PF00316.20 CBY10016.1 - 1.8e-68 229.8 0.5 2.4e-68 229.3 0.5 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CBY10016.1 - 0.012 15.1 0.0 0.073 12.6 0.0 2.0 2 0 0 2 2 2 0 Inositol monophosphatase family HA2 PF04408.23 CBY10017.1 - 2.9e-16 59.7 2.6 1.2e-15 57.7 1.0 2.8 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY10017.1 - 9.4e-14 51.7 0.0 2.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBY10017.1 - 1.5e-09 38.1 0.0 3.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBY10017.1 - 0.00027 20.8 1.1 0.0013 18.6 1.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY10017.1 - 0.0061 16.8 1.1 0.028 14.7 1.1 2.1 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBY10017.1 - 0.022 13.8 0.0 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 CBY10017.1 - 0.037 14.0 1.7 0.13 12.2 0.1 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2407_C PF13373.6 CBY10017.1 - 0.043 14.0 1.0 1.7 8.8 0.8 2.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain ABC_tran PF00005.27 CBY10017.1 - 1.7 9.1 4.4 8 7.0 0.0 2.9 3 0 0 3 3 3 0 ABC transporter Folate_rec PF03024.14 CBY10018.1 - 3.2e-34 118.3 22.9 9.2e-18 64.7 7.0 2.1 2 0 0 2 2 2 2 Folate receptor family Peptidase_S8 PF00082.22 CBY10019.1 - 3.9e-37 128.1 0.4 5.9e-37 127.5 0.4 1.3 1 0 0 1 1 1 1 Subtilase family Chalcone_N PF18232.1 CBY10019.1 - 0.12 12.7 0.0 0.41 11.1 0.0 1.9 1 0 0 1 1 1 0 Chalcone isomerase N-terminal domain MIEAP PF16026.5 CBY10020.1 - 0.018 15.3 0.8 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondria-eating protein LRR_8 PF13855.6 CBY10020.1 - 0.067 13.0 3.2 0.84 9.5 0.2 3.3 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 CBY10020.1 - 0.093 13.2 10.1 0.83 10.2 0.3 4.2 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY10020.1 - 1.4 9.8 3.6 19 6.3 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat DUF572 PF04502.13 CBY10021.1 - 1.3e-59 202.5 12.5 1.6e-59 202.2 12.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 CBY10021.1 - 0.018 15.0 0.4 0.78 9.7 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DNA_RNApol_7kD PF03604.13 CBY10021.1 - 0.031 13.9 1.5 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit SIR2 PF02146.17 CBY10022.1 - 2e-48 164.6 0.0 2.8e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-C2H2_12 PF18658.1 CBY10022.1 - 0.19 11.3 0.4 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger C2H2-type PH PF00169.29 CBY10023.1 - 3e-09 37.3 0.0 5.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CBY10023.1 - 2.7e-06 27.6 0.0 6.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 CBY10023.1 - 0.00016 22.0 0.0 0.00049 20.4 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBY10023.1 - 0.042 14.3 0.1 0.16 12.4 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain DUF4398 PF14346.6 CBY10023.1 - 0.26 11.9 3.3 0.47 11.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) zf-RING_2 PF13639.6 CBY10024.1 - 2e-12 47.2 6.5 3.5e-12 46.5 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBY10024.1 - 2.7e-08 33.9 8.4 9.4e-08 32.2 8.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBY10024.1 - 2.6e-07 30.4 5.9 4.5e-07 29.6 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY10024.1 - 2.9e-07 30.3 5.4 5.1e-07 29.5 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY10024.1 - 8.9e-07 28.8 2.7 1.7e-06 27.9 2.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CBY10024.1 - 1.8e-06 27.6 2.6 3.3e-06 26.7 2.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 CBY10024.1 - 2.3e-06 27.1 2.8 4.9e-06 26.1 2.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CBY10024.1 - 4.1e-06 26.6 3.3 8e-06 25.6 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY10024.1 - 4.4e-05 23.4 5.6 0.00014 21.8 5.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY10024.1 - 0.00019 21.2 3.7 0.00046 20.0 3.7 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CBY10024.1 - 0.004 17.3 1.4 0.0094 16.1 1.4 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING-like PF08746.11 CBY10024.1 - 0.0045 17.3 5.5 0.0072 16.6 5.5 1.3 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 CBY10024.1 - 0.0061 16.6 4.6 0.041 13.9 4.6 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 CBY10024.1 - 0.07 13.4 1.6 0.18 12.0 1.6 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zinc_ribbon_16 PF17034.5 CBY10024.1 - 0.08 13.2 0.8 0.18 12.0 0.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family RINGv PF12906.7 CBY10024.1 - 0.36 11.0 5.7 0.93 9.7 5.7 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 CBY10024.1 - 0.5 10.5 1.5 1.2 9.2 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 CBY10024.1 - 0.68 9.8 2.8 1.4 8.8 2.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CBY10024.1 - 0.74 10.0 4.3 1.6 8.9 4.3 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Leu_zip PF15294.6 CBY10025.1 - 5.3e-55 186.9 25.3 9.5e-42 143.4 10.7 2.0 1 1 1 2 2 2 2 Leucine zipper Nrap_D6 PF17407.2 CBY10025.1 - 0.029 14.6 0.1 0.029 14.6 0.1 2.5 2 1 0 2 2 2 0 Nrap protein domain 6 dsrm PF00035.26 CBY10026.1 - 2.6e-28 98.5 1.7 1.3e-09 38.6 0.0 3.5 3 0 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.7 CBY10026.1 - 9e-12 45.1 0.9 0.049 13.9 0.1 4.3 3 1 0 3 3 3 3 double strand RNA binding domain from DEAD END PROTEIN 1 BTB PF00651.31 CBY10026.1 - 4.9e-09 36.4 0.3 1.2e-08 35.2 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain Dicer_dimer PF03368.14 CBY10026.1 - 5.6e-05 23.2 0.9 5.6 7.2 0.0 3.6 3 0 0 3 3 3 3 Dicer dimerisation domain Ephrin_rec_like PF07699.13 CBY10027.1 - 0.00028 20.6 34.7 0.00047 19.9 6.3 82.4 69 17 18 88 88 88 36 Putative ephrin-receptor like SirA PF10747.9 CBY10027.1 - 2.9 8.2 7.0 13 6.1 4.8 3.0 2 1 1 3 3 3 0 Sporulation inhibitor of replication protein SirA Arm PF00514.23 CBY10028.1 - 8.8e-77 251.1 15.2 1.7e-10 40.5 0.0 8.9 8 1 1 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CBY10028.1 - 7.4e-21 73.5 0.9 3.3e-20 71.4 1.3 1.9 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 CBY10028.1 - 1e-17 64.3 5.5 2.3e-17 63.2 5.5 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 CBY10028.1 - 4.3e-16 59.0 5.7 0.0011 19.4 0.0 6.4 3 2 2 6 6 6 6 HEAT-like repeat HEAT_2 PF13646.6 CBY10028.1 - 7.8e-14 51.8 1.8 3.7e-05 24.0 0.3 6.5 2 1 6 8 8 8 5 HEAT repeats HEAT PF02985.22 CBY10028.1 - 1.6e-12 46.5 3.3 0.011 15.9 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 CBY10028.1 - 1.3e-07 30.6 0.1 3.8e-07 29.1 0.1 1.9 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 CBY10028.1 - 6.8e-06 26.2 0.3 3.7 7.7 0.0 4.4 4 0 0 4 4 4 2 V-ATPase subunit H Cnd1 PF12717.7 CBY10028.1 - 9.3e-06 25.8 0.0 1.1 9.2 0.0 3.7 1 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 DCB PF16213.5 CBY10028.1 - 0.081 12.6 0.0 1.2 8.7 0.0 2.7 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 FF PF01846.19 CBY10029.1 - 3.1e-25 88.1 13.4 1.9e-14 53.6 0.5 6.3 6 0 0 6 6 6 4 FF domain WW PF00397.26 CBY10029.1 - 1.6e-16 60.0 9.8 1.7e-08 34.4 1.7 2.5 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 CBY10029.1 - 0.0054 17.4 8.1 0.032 14.9 0.8 3.2 2 0 0 2 2 2 2 p190-A and -B Rho GAPs FF domain Gp49 PF05973.14 CBY10029.1 - 0.026 14.6 0.4 0.026 14.6 0.4 3.2 4 0 0 4 4 4 0 Phage derived protein Gp49-like (DUF891) Voltage_CLC PF00654.20 CBY10030.1 - 1.3e-77 261.5 23.7 1.3e-77 261.5 23.7 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBY10030.1 - 7.8e-08 32.6 0.3 0.024 15.1 0.1 2.7 2 0 0 2 2 2 2 CBS domain Med14 PF08638.11 CBY10031.1 - 1e-59 201.2 1.2 1.5e-59 200.6 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit MED14 ST7 PF04184.12 CBY10032.1 - 4.1e-224 745.0 0.9 5.2e-224 744.7 0.9 1.0 1 0 0 1 1 1 1 ST7 protein TPR_19 PF14559.6 CBY10032.1 - 1.4e-08 35.1 2.7 0.051 14.1 0.5 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY10032.1 - 9.7e-05 22.9 0.8 4.2 8.4 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY10032.1 - 0.00073 19.5 5.0 0.069 13.3 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY10032.1 - 0.0013 19.3 4.8 0.59 10.9 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY10032.1 - 0.0015 18.2 3.3 8.7 6.3 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY10032.1 - 0.0031 17.4 0.1 0.97 9.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Clathrin PF00637.20 CBY10032.1 - 0.0036 17.2 0.2 0.0091 15.9 0.2 1.6 1 1 0 1 1 1 1 Region in Clathrin and VPS TPR_16 PF13432.6 CBY10032.1 - 0.015 15.9 2.7 0.4 11.4 0.1 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY10032.1 - 0.065 12.9 0.4 0.77 9.5 0.0 2.8 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.6 CBY10032.1 - 0.066 13.4 3.3 5.7 7.4 0.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY10032.1 - 0.071 13.4 2.9 11 6.4 0.3 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY10032.1 - 0.12 12.7 2.4 3.2 8.0 0.4 2.9 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4537 PF15057.6 CBY10033.1 - 0.0031 17.5 1.6 0.08 13.0 0.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 CBY10033.1 - 0.014 15.2 1.8 0.049 13.5 0.9 2.2 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain TMEM206 PF15122.6 CBY10033.1 - 0.028 13.6 0.1 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 TMEM206 protein family Agenet PF05641.12 CBY10033.1 - 0.11 13.0 1.4 4 8.0 0.1 2.4 2 0 0 2 2 2 0 Agenet domain CAP_GLY PF01302.25 CBY10033.1 - 0.9 9.6 3.8 0.67 10.0 0.2 2.2 2 0 0 2 2 2 0 CAP-Gly domain COX5A PF02284.16 CBY10034.1 - 4.1e-26 91.0 0.0 5.6e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF3144 PF11342.8 CBY10034.1 - 0.049 13.9 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) Ribosomal_L6e PF01159.19 CBY10035.1 - 9.3e-29 100.2 9.7 2.4e-28 98.9 1.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6e Rad21_Rec8_N PF04825.13 CBY10036.1 - 1.1e-09 38.5 0.1 2.9e-09 37.1 0.1 1.7 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CBY10036.1 - 8.9e-05 21.7 0.0 0.00029 20.0 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 CBY10036.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Tudor_2 PF18104.1 CBY10037.1 - 2.5e-07 30.2 3.8 0.017 14.8 0.3 3.6 4 0 0 4 4 4 2 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 CBY10037.1 - 8.6e-05 22.5 0.2 0.18 11.8 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) TUDOR_5 PF18359.1 CBY10037.1 - 0.00022 20.9 0.3 0.41 10.4 0.0 2.9 3 0 0 3 3 3 2 Histone methyltransferase Tudor domain 1 zf-C2H2 PF00096.26 CBY10037.1 - 1.2 9.7 3.3 2.9 8.5 3.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Tox-SHH PF15652.6 CBY10037.1 - 8.2 7.4 11.1 4.2 8.4 0.8 4.5 3 0 0 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature NHL PF01436.21 CBY10040.1 - 4.7e-06 26.4 0.0 0.00016 21.6 0.0 2.8 3 0 0 3 3 3 1 NHL repeat PQQ_2 PF13360.6 CBY10040.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Ephrin PF00812.17 CBY10042.1 - 6.2e-42 142.9 0.0 9.6e-42 142.2 0.0 1.3 1 0 0 1 1 1 1 Ephrin UNC-93 PF05978.16 CBY10043.1 - 0.37 10.5 22.0 0.13 12.0 1.1 3.8 4 0 0 4 4 4 0 Ion channel regulatory protein UNC-93 Ion_trans PF00520.31 CBY10044.1 - 9.2e-238 784.8 74.7 2e-71 240.1 7.2 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CBY10044.1 - 3.9e-15 55.5 82.3 6.3e-05 21.8 5.0 10.0 7 3 1 9 9 9 8 Polycystin cation channel DUF4446 PF14584.6 CBY10044.1 - 0.025 14.6 1.3 1.3 9.0 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Colipase-like PF15083.6 CBY10044.1 - 0.14 12.3 6.4 6.2 7.0 1.5 3.1 2 0 0 2 2 2 0 Colipase-like Ctr PF04145.15 CBY10044.1 - 1.2 9.7 12.1 0.59 10.7 0.1 4.5 4 1 0 4 4 4 0 Ctr copper transporter family Pribosyl_synth PF14572.6 CBY10047.1 - 4.6e-52 176.7 2.2 7e-51 172.9 2.2 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CBY10047.1 - 1.8e-39 134.3 1.7 9.5e-39 131.9 0.5 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CBY10047.1 - 4.1e-06 26.4 0.1 1.3e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Glyco_tran_WecB PF03808.13 CBY10047.1 - 0.035 14.1 0.2 0.25 11.3 0.0 2.3 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Cadherin_C_2 PF16492.5 CBY10048.1 - 0.035 14.9 0.0 2.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4079 PF13301.6 CBY10048.1 - 0.077 13.2 0.0 0.15 12.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF5513 PF17632.2 CBY10049.1 - 0.22 12.0 0.3 24 5.4 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5513) eIF3_subunit PF08597.10 CBY10050.1 - 0.02 14.8 16.6 0.038 13.9 16.6 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Med26 PF08711.11 CBY10050.1 - 0.061 13.4 0.3 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 TFIIS helical bundle-like domain DNA_pol_E_B PF04042.16 CBY10050.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B XRCC1_N PF01834.16 CBY10051.1 - 2.1e-21 76.5 0.1 4e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT PF00533.26 CBY10051.1 - 1e-13 51.4 0.2 3e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CBY10051.1 - 8.1e-13 48.1 0.0 3.4e-09 36.5 0.0 2.6 2 0 0 2 2 2 2 twin BRCT domain BRCT_2 PF16589.5 CBY10051.1 - 9.5e-13 48.4 0.1 2.6e-11 43.8 0.1 2.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY10051.1 - 0.0002 21.6 0.0 0.00075 19.7 0.0 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain IFT20 PF14931.6 CBY10052.1 - 5.5e-29 100.7 12.4 6.4e-29 100.6 12.4 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF3450 PF11932.8 CBY10052.1 - 0.6 9.4 14.0 0.4 10.0 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MutS_III PF05192.18 CBY10052.1 - 0.8 9.9 6.3 1 9.6 6.3 1.1 1 0 0 1 1 1 0 MutS domain III Mitofilin PF09731.9 CBY10053.1 - 6.8e-09 35.1 0.0 7.1e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Lactamase_B_6 PF16661.5 CBY10054.1 - 0.069 12.6 0.4 0.31 10.5 0.2 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain DMSP_lyase PF16867.5 CBY10054.1 - 0.11 12.1 0.1 0.56 9.8 0.1 2.2 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase ParE_toxin PF05016.15 CBY10054.1 - 0.15 12.7 0.5 0.76 10.4 0.2 2.3 1 1 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Peptidase_M16 PF00675.20 CBY10055.1 - 4.9e-17 62.3 0.0 8.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBY10055.1 - 5.8e-08 33.0 0.0 3.5e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF3402 PF11882.8 CBY10056.1 - 3.9e-63 214.2 11.3 2.8e-37 128.9 2.5 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 CBY10056.1 - 0.004 16.4 0.0 0.0094 15.2 0.0 1.6 1 0 0 1 1 1 1 N1221-like protein Peptidase_M16 PF00675.20 CBY10057.1 - 1.7e-16 60.5 0.0 3.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBY10057.1 - 1.7e-12 47.7 0.0 4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2695 PF10905.8 CBY10057.1 - 0.087 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) WD40 PF00400.32 CBY10058.1 - 5.6e-18 65.0 1.2 0.0036 18.1 0.0 6.2 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY10058.1 - 8.7e-09 35.6 0.0 3.3e-05 24.1 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY10058.1 - 0.019 14.0 0.0 0.055 12.4 0.0 1.8 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cwf_Cwc_15 PF04889.12 CBY10058.1 - 0.29 10.8 11.9 0.61 9.8 11.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 CBY10059.1 - 4.6e-42 144.2 0.0 6.2e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10059.1 - 8e-14 51.5 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY10059.1 - 0.00013 21.3 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY10059.1 - 0.00065 19.1 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY10059.1 - 0.0039 16.2 0.1 0.0061 15.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY10059.1 - 0.016 15.1 0.1 0.047 13.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY10059.1 - 1.8 7.2 4.1 5.3 5.7 4.2 1.9 1 1 0 1 1 1 0 Fungal protein kinase LRR_4 PF12799.7 CBY10060.1 - 2.2e-09 37.4 10.5 0.0013 19.1 1.0 4.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY10060.1 - 2.5e-07 30.3 10.3 0.001 18.8 4.2 3.9 3 1 1 4 4 4 3 Leucine rich repeat Methyltransf_22 PF13383.6 CBY10060.1 - 0.006 16.2 0.2 0.0091 15.6 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain LRR_1 PF00560.33 CBY10060.1 - 3.8 8.4 10.9 34 5.5 0.0 5.4 7 0 0 7 7 7 0 Leucine Rich Repeat zf-RING_2 PF13639.6 CBY10061.1 - 1.4e-08 34.9 8.9 1.4e-08 34.9 8.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY10061.1 - 0.00011 21.9 10.0 0.00029 20.6 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY10061.1 - 0.00017 21.4 10.1 0.00042 20.1 10.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY10061.1 - 0.0046 16.9 11.3 0.0046 16.9 11.3 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-P11 PF03854.14 CBY10061.1 - 0.0072 16.0 6.2 0.032 13.9 6.2 2.1 1 1 0 1 1 1 1 P-11 zinc finger zf-RING_4 PF14570.6 CBY10061.1 - 0.0073 16.1 9.2 0.019 14.8 9.2 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 CBY10061.1 - 0.012 15.4 6.9 0.012 15.4 1.9 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 CBY10061.1 - 0.021 15.1 8.5 0.18 12.1 8.5 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 CBY10061.1 - 0.04 14.1 4.0 0.04 14.1 4.0 2.9 2 1 1 3 3 3 0 FYVE zinc finger Prok-RING_4 PF14447.6 CBY10061.1 - 0.047 13.6 7.8 0.3 11.0 7.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rtf2 PF04641.12 CBY10061.1 - 0.29 10.5 8.7 2.5 7.4 8.6 2.1 1 1 0 1 1 1 0 Rtf2 RING-finger Baculo_IE-1 PF05290.11 CBY10061.1 - 0.34 10.8 9.5 0.69 9.9 9.5 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 CBY10061.1 - 0.37 10.7 15.5 0.05 13.5 11.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2321 PF10083.9 CBY10061.1 - 0.47 10.1 7.4 0.25 10.9 5.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C3HC4_4 PF15227.6 CBY10061.1 - 5.1 7.3 11.4 7.9 6.7 7.2 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF983 PF06170.12 CBY10061.1 - 9.6 6.7 6.3 3.5 8.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF983) Laminin_G_3 PF13385.6 CBY10062.1 - 0.0038 17.4 0.1 0.0099 16.0 0.1 1.6 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 CBY10062.1 - 0.09 13.4 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain PLAT PF01477.23 CBY10063.1 - 3.2e-19 69.6 0.5 1.6e-18 67.3 0.2 2.1 2 0 0 2 2 2 1 PLAT/LH2 domain Lipoxygenase PF00305.19 CBY10063.1 - 0.00036 19.1 0.0 0.0015 17.0 0.0 1.6 1 1 1 2 2 2 1 Lipoxygenase ATS3 PF06232.11 CBY10063.1 - 0.0037 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) DUF2436 PF10365.9 CBY10063.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Lipoxygenase PF00305.19 CBY10064.1 - 9.5e-57 192.9 0.0 8.9e-55 186.3 0.0 2.0 1 1 0 1 1 1 1 Lipoxygenase eIF-3c_N PF05470.12 CBY10064.1 - 0.031 12.6 0.1 0.049 11.9 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Glyco_hydro_9 PF00759.19 CBY10065.1 - 3.4e-128 428.6 2.3 4.4e-128 428.2 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CD36 PF01130.21 CBY10066.1 - 2.5e-54 184.6 0.0 2.9e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 CD36 family GARS_A PF01071.19 CBY10068.1 - 0.053 13.3 0.1 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LRR_9 PF14580.6 CBY10069.1 - 2.5e-85 284.3 3.1 3.5e-85 283.9 3.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBY10069.1 - 8.5e-13 48.3 8.8 6.5e-09 35.9 1.0 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY10069.1 - 4.1e-11 42.5 0.2 4.1e-11 42.5 0.2 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 CBY10069.1 - 0.36 11.6 5.9 30 5.7 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 CBY10069.1 - 3.8 7.8 4.4 17 5.7 0.3 3.7 4 0 0 4 4 4 0 Leucine Rich repeat BTB PF00651.31 CBY10070.1 - 4.8e-33 113.7 0.0 8.3e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 CBY10070.1 - 0.0079 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.15 CBY10070.1 - 0.087 13.0 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain LRR_9 PF14580.6 CBY10071.1 - 2.5e-85 284.4 3.1 3.4e-85 283.9 3.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBY10071.1 - 8.9e-13 48.2 8.8 6.5e-09 35.9 1.0 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY10071.1 - 4e-11 42.5 0.2 4e-11 42.5 0.2 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 CBY10071.1 - 0.37 11.5 5.9 30 5.7 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 CBY10071.1 - 3.8 7.8 4.4 17 5.7 0.3 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Kelch_1 PF01344.25 CBY10072.1 - 4.8e-73 240.5 16.6 6.5e-14 51.3 0.6 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 CBY10072.1 - 8e-38 127.5 2.6 2.3e-07 30.8 0.1 6.5 3 2 3 6 6 6 6 Kelch motif BTB PF00651.31 CBY10072.1 - 5.3e-33 113.6 0.0 9.4e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY10072.1 - 8.1e-31 106.2 1.3 8.1e-31 106.2 1.3 2.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CBY10072.1 - 1.1e-22 79.8 6.0 0.00057 19.8 0.1 6.2 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY10072.1 - 1.1e-22 79.8 7.5 3.5e-07 30.3 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY10072.1 - 8e-18 63.7 6.5 0.022 14.7 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 CBY10072.1 - 6.7e-05 22.8 8.2 0.51 10.4 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Glyoxal_oxid_N PF07250.11 CBY10072.1 - 0.00041 19.6 0.8 0.33 10.1 0.2 2.9 2 1 1 3 3 3 3 Glyoxal oxidase N-terminus DUF3342 PF11822.8 CBY10072.1 - 0.0021 18.2 0.2 0.018 15.3 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.15 CBY10072.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DAO_C PF16901.5 CBY10072.1 - 0.14 12.0 0.0 8.6 6.3 0.0 2.7 2 0 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase PQQ_3 PF13570.6 CBY10072.1 - 4.4 7.9 12.4 7.9 7.1 0.2 4.1 4 0 0 4 4 4 0 PQQ-like domain MPDZ_u10 PF16667.5 CBY10073.1 - 0.2 12.6 16.7 0.61 11.0 1.6 2.9 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein Aa_trans PF01490.18 CBY10074.1 - 1.4e-61 208.5 18.2 1.9e-61 208.0 18.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3784 PF12650.7 CBY10074.1 - 0.12 12.6 0.1 0.12 12.6 0.1 5.4 4 2 2 6 6 6 0 Domain of unknown function (DUF3784) FYVE PF01363.21 CBY10075.1 - 0.072 13.2 13.4 0.16 12.1 13.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger DUF2439 PF10382.9 CBY10076.1 - 4.7e-08 33.2 0.0 1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) B56 PF01603.20 CBY10078.1 - 1.1e-141 472.6 9.3 1.3e-141 472.4 9.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) XPC-binding PF09280.11 CBY10078.1 - 0.013 15.2 0.4 0.05 13.3 0.4 2.1 1 0 0 1 1 1 0 XPC-binding domain ArsC PF03960.15 CBY10078.1 - 0.073 13.1 0.2 0.23 11.5 0.2 1.8 1 0 0 1 1 1 0 ArsC family Sec7_N PF12783.7 CBY10078.1 - 0.089 12.7 4.3 7.3 6.5 0.0 3.5 2 2 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Forkhead PF00250.18 CBY10079.1 - 2.1e-37 127.2 0.2 4.4e-37 126.2 0.0 1.7 2 0 0 2 2 2 1 Forkhead domain DUF2407_C PF13373.6 CBY10080.1 - 0.059 13.6 1.0 0.72 10.0 0.0 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain MFS_1 PF07690.16 CBY10082.1 - 9.5e-25 87.3 19.7 2.3e-24 86.0 19.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CBY10082.1 - 2.3e-07 29.8 27.5 1.7e-06 26.9 12.5 2.5 1 1 2 3 3 3 2 MFS/sugar transport protein TMEM234 PF10639.9 CBY10082.1 - 0.01 15.8 5.8 0.012 15.6 2.8 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 DHHC PF01529.20 CBY10082.1 - 0.11 12.6 0.3 0.11 12.6 0.3 4.1 3 2 0 3 3 3 0 DHHC palmitoyltransferase DUF3413 PF11893.8 CBY10082.1 - 0.56 9.3 25.0 0.21 10.7 8.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3413) EphA2_TM PF14575.6 CBY10082.1 - 2.1 9.3 0.0 2.1 9.3 0.0 3.5 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Kinetochor_Ybp2 PF08568.10 CBY10083.1 - 0.0013 17.3 0.0 0.0014 17.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin TetR_C_34 PF17929.1 CBY10083.1 - 0.019 15.1 0.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain VIR_N PF15912.5 CBY10084.1 - 2.1e-05 24.3 0.0 2.1e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Virilizer, N-terminal GTP_EFTU PF00009.27 CBY10085.1 - 8.4e-57 191.8 0.1 3.7e-56 189.7 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CBY10085.1 - 3.4e-17 62.2 0.0 1.6e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 CBY10085.1 - 4.9e-07 29.7 0.1 1.1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CBY10085.1 - 4.8e-06 26.9 0.3 1.4e-05 25.4 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY10085.1 - 0.00017 21.7 0.1 0.00038 20.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 CBY10085.1 - 0.0007 19.4 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV RsgA_GTPase PF03193.16 CBY10085.1 - 0.1 12.5 0.1 0.83 9.5 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase GvpO PF05800.11 CBY10085.1 - 0.17 11.9 1.2 4.5 7.3 0.0 3.0 3 0 0 3 3 3 0 Gas vesicle synthesis protein GvpO ECR1_N PF14382.6 CBY10089.1 - 2.7e-13 49.5 0.0 5.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CBY10089.1 - 3.1e-08 33.8 0.3 6.8e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 KH domain Fer4 PF00037.27 CBY10090.1 - 7.8e-16 57.1 16.6 2.8e-09 36.4 4.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CBY10090.1 - 1.4e-13 51.2 11.1 2.1e-13 50.6 11.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CBY10090.1 - 5.1e-12 46.5 6.0 1.1e-05 26.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CBY10090.1 - 1.8e-11 44.0 31.9 2.5e-07 30.7 12.0 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBY10090.1 - 1.2e-10 41.3 20.6 3.4e-07 30.3 12.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBY10090.1 - 1.5e-09 37.9 10.6 2.3e-09 37.3 10.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBY10090.1 - 3.2e-09 37.1 3.5 0.00017 22.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBY10090.1 - 2.1e-08 33.9 18.2 0.00025 21.0 5.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CBY10090.1 - 2.6e-07 30.3 12.8 0.0016 18.4 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CBY10090.1 - 1e-06 28.8 10.5 0.00024 21.4 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBY10090.1 - 2.2e-05 24.9 11.4 0.018 15.6 1.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 CBY10090.1 - 0.0038 17.7 13.8 0.35 11.4 3.8 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 CBY10090.1 - 0.0081 16.4 7.9 0.22 11.7 0.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 CBY10090.1 - 0.0087 16.9 17.4 0.038 14.9 4.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 CBY10090.1 - 0.014 15.6 5.4 1.2 9.4 0.5 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ETF_QO PF05187.13 CBY10090.1 - 0.024 14.8 4.1 0.096 12.8 0.2 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CBY10090.1 - 0.45 11.4 11.9 1.8 9.5 1.8 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain MAS20 PF02064.15 CBY10091.1 - 1.4e-10 41.4 0.0 1.4e-10 41.4 0.0 2.5 2 1 0 2 2 2 1 MAS20 protein import receptor SDA1 PF05285.12 CBY10091.1 - 1.3 8.4 9.8 2 7.8 9.8 1.1 1 0 0 1 1 1 0 SDA1 DEAD PF00270.29 CBY10092.1 - 4.8e-49 166.5 0.0 7.4e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY10092.1 - 5.3e-30 104.0 0.0 1.5e-29 102.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY10092.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit EIIA-man PF03610.16 CBY10092.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 PTS system fructose IIA component UCH PF00443.29 CBY10093.1 - 8.5e-35 120.5 5.5 8.5e-35 120.5 5.5 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY10093.1 - 2.8e-08 33.8 19.4 6.1e-07 29.3 19.4 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Coat_F PF07875.12 CBY10093.1 - 0.11 12.7 0.0 0.52 10.6 0.0 2.2 1 0 0 1 1 1 0 Coat F domain Thiolase_N PF00108.23 CBY10094.1 - 2.8e-76 256.3 4.0 4.1e-76 255.8 4.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY10094.1 - 2.7e-44 149.8 2.7 6.4e-44 148.5 0.4 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY10094.1 - 5.7e-06 26.1 2.4 5.7e-06 26.1 2.4 2.4 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CBY10094.1 - 0.045 13.6 1.2 6.3 6.7 0.3 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III eIF3_N PF09440.10 CBY10095.1 - 1.8e-28 99.6 2.3 1.8e-28 99.6 2.3 2.3 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CBY10095.1 - 2.8e-15 56.7 1.0 1.3e-14 54.6 1.0 2.2 1 1 0 1 1 1 1 PCI domain E3_UFM1_ligase PF09743.9 CBY10095.1 - 0.0012 18.5 0.7 0.0022 17.7 0.1 1.7 2 0 0 2 2 2 1 E3 UFM1-protein ligase 1 GerD PF17898.1 CBY10095.1 - 0.0019 18.1 0.5 0.007 16.3 0.5 2.0 1 0 0 1 1 1 1 Spore germination GerD central core domain CSN8_PSD8_EIF3K PF10075.9 CBY10095.1 - 0.0026 17.7 0.3 0.0074 16.3 0.3 1.8 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HMW1C_N PF18071.1 CBY10095.1 - 0.0043 16.8 1.9 3 7.6 0.1 3.3 3 0 0 3 3 3 2 HMW1C N-terminal DUF771 PF05595.11 CBY10095.1 - 0.017 15.1 2.1 0.12 12.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF771) LEDGF PF11467.8 CBY10095.1 - 0.021 14.5 0.3 0.066 12.8 0.3 1.8 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Mod_r PF07200.13 CBY10095.1 - 0.037 14.1 2.6 0.072 13.2 0.3 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Acyltransferase PF01553.21 CBY10096.1 - 1.3e-15 57.2 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CBY10096.1 - 3.6e-12 46.2 0.0 6.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF2232 PF09991.9 CBY10096.1 - 0.015 14.5 3.5 0.015 14.5 3.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Ion_trans PF00520.31 CBY10098.1 - 5.4e-11 42.2 16.1 5.4e-11 42.2 16.1 2.5 2 1 0 2 2 2 1 Ion transport protein Glyco_trans_2_3 PF13632.6 CBY10098.1 - 7.4 6.4 9.6 24 4.8 9.6 1.9 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Ifi-6-16 PF06140.13 CBY10099.1 - 9.7e-15 54.3 31.7 1.2e-14 53.9 31.7 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family Dehydrin PF00257.19 CBY10099.1 - 1.5 9.4 4.7 1.7 9.1 4.7 1.1 1 0 0 1 1 1 0 Dehydrin Ifi-6-16 PF06140.13 CBY10100.1 - 5.4e-09 35.8 30.1 7.1e-09 35.5 30.1 1.1 1 0 0 1 1 1 1 Interferon-induced 6-16 family Homeodomain PF00046.29 CBY10101.1 - 2.8e-23 81.5 6.3 2.8e-23 81.5 6.3 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY10101.1 - 0.015 15.2 0.4 0.047 13.6 0.4 1.9 1 0 0 1 1 1 0 Homeobox KN domain TFIIA PF03153.13 CBY10101.1 - 5.1 7.0 11.7 8.4 6.3 11.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Homeodomain PF00046.29 CBY10102.1 - 1.1e-24 86.1 4.0 1.1e-24 86.0 2.0 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY10102.1 - 0.012 15.5 0.1 0.033 14.1 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 CBY10102.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT UQ_con PF00179.26 CBY10104.1 - 1.6e-08 34.3 0.1 2.7e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SNRNP27 PF08648.12 CBY10104.1 - 0.014 15.4 0.4 0.03 14.4 0.4 1.5 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins BRD4_CDT PF17105.5 CBY10104.1 - 0.099 12.3 0.6 0.25 11.0 0.6 1.6 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Peptidase_C2 PF00648.21 CBY10105.1 - 9.1e-83 277.7 0.1 5.6e-76 255.4 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 CBY10105.1 - 1.2e-38 132.5 0.0 2.1e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 CBY10105.1 - 2.7e-06 26.9 0.1 5.8e-05 22.7 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY10105.1 - 8e-05 21.9 2.4 0.00024 20.4 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CBY10105.1 - 0.00015 22.2 1.5 0.002 18.5 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair Rhodanese PF00581.20 CBY10106.1 - 6.4e-12 45.9 0.0 1.5e-11 44.8 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain COG2 PF06148.11 CBY10107.1 - 0.041 14.0 0.8 0.041 14.0 0.8 3.5 5 0 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.13 CBY10107.1 - 0.11 13.2 3.1 0.4 11.4 0.3 3.2 3 0 0 3 3 3 0 Occludin homology domain FlxA PF14282.6 CBY10107.1 - 0.12 12.3 3.8 0.61 10.1 0.2 2.9 2 0 0 2 2 2 0 FlxA-like protein DUF4407 PF14362.6 CBY10107.1 - 0.17 11.2 3.5 0.56 9.5 0.2 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 CBY10107.1 - 0.2 11.9 8.9 0.63 10.3 0.2 5.0 4 2 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF4927 PF16279.5 CBY10107.1 - 0.33 12.0 2.1 0.51 11.4 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4927) FliD_C PF07195.12 CBY10107.1 - 0.54 9.6 7.7 3.1 7.1 3.8 3.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus UPF0242 PF06785.11 CBY10107.1 - 0.6 10.2 13.1 0.14 12.2 2.0 3.1 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus kleA_kleC PF17383.2 CBY10107.1 - 1.4 9.3 5.1 3.5 8.0 0.0 3.9 5 1 0 5 5 5 0 Uncharacterized KorC regulated protein A Cob_adeno_trans PF01923.18 CBY10107.1 - 7 6.8 6.2 2.9 8.0 0.2 3.2 3 2 2 5 5 5 0 Cobalamin adenosyltransferase BLOC1_2 PF10046.9 CBY10107.1 - 9 6.7 13.1 5.8 7.3 0.1 4.9 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Borrelia_P83 PF05262.11 CBY10108.1 - 0.017 13.6 21.2 0.022 13.2 21.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Abhydrolase_6 PF12697.7 CBY10110.1 - 3.6e-11 44.1 0.0 4.3e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBY10110.1 - 2.3e-10 40.6 0.2 2.8e-10 40.3 0.2 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBY10110.1 - 3.6e-08 33.0 0.0 5.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CBY10110.1 - 0.0046 17.1 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF1100 PF06500.11 CBY10110.1 - 0.017 13.9 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) PRP38 PF03371.15 CBY10112.1 - 1.4e-56 191.1 0.0 1.8e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Steroid_dh PF02544.16 CBY10113.1 - 1.8e-52 177.3 2.1 3.5e-52 176.4 2.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CBY10113.1 - 7.6e-06 25.6 0.3 1.3e-05 24.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Pkinase PF00069.25 CBY10114.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Phostensin PF13914.6 CBY10114.1 - 0.042 14.5 1.2 0.054 14.1 1.1 1.4 1 1 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Pkinase PF00069.25 CBY10115.1 - 8.1e-32 110.6 0.0 1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10115.1 - 8.4e-23 81.0 0.0 1.1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 CBY10115.1 - 0.0025 16.9 0.1 0.004 16.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 CBY10115.1 - 0.0026 17.1 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY10115.1 - 0.012 14.6 0.8 0.015 14.3 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain HMG_box PF00505.19 CBY10116.1 - 2.4e-09 37.5 1.1 2.4e-09 37.5 1.1 3.5 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY10116.1 - 0.0003 21.3 0.6 0.0003 21.3 0.6 3.3 3 1 0 3 3 3 1 HMG-box domain PEP-utilisers_N PF05524.13 CBY10116.1 - 0.035 14.3 7.8 0.43 10.8 0.3 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal ACT_5 PF13710.6 CBY10116.1 - 0.048 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 ACT domain DUF1018 PF06252.12 CBY10116.1 - 0.98 10.4 11.9 1.1 10.3 5.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) DUF4407 PF14362.6 CBY10116.1 - 4.7 6.5 8.5 6 6.1 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HMG_box PF00505.19 CBY10117.1 - 1.2e-14 54.5 4.4 1.2e-14 54.5 4.4 3.0 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY10117.1 - 7.9e-12 45.6 2.2 7.9e-12 45.6 2.2 2.8 3 1 0 3 3 3 1 HMG-box domain PEP-utilisers_N PF05524.13 CBY10117.1 - 3 8.1 8.7 3.6 7.8 0.9 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal MFS_1 PF07690.16 CBY10119.1 - 7.4e-11 41.6 6.9 1.1e-10 40.9 6.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5560 PF17715.1 CBY10119.1 - 0.18 11.2 0.1 0.29 10.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Forkhead PF00250.18 CBY10121.1 - 6.5e-38 128.9 0.1 1.2e-37 128.0 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain TMEM65 PF10507.9 CBY10122.1 - 1.2e-43 147.5 0.6 1.5e-43 147.1 0.6 1.1 1 0 0 1 1 1 1 Transmembrane protein 65 AAA_13 PF13166.6 CBY10124.1 - 7 5.2 49.7 1.5 7.4 18.4 2.0 1 1 1 2 2 2 0 AAA domain DUF1664 PF07889.12 CBY10124.1 - 7.3 6.7 32.6 0.33 11.0 2.4 4.4 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF2959 PF11172.8 CBY10125.1 - 0.0012 19.0 7.0 0.024 14.8 7.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2959) DUF1054 PF06335.12 CBY10125.1 - 0.013 15.5 3.1 0.21 11.5 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1054) partial_CstF PF15861.5 CBY10125.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain CENP-F_leu_zip PF10473.9 CBY10125.1 - 0.018 15.0 1.3 0.018 15.0 1.3 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 CBY10125.1 - 0.032 14.5 15.6 0.059 13.6 15.6 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 AAA_13 PF13166.6 CBY10125.1 - 0.061 12.0 10.4 0.069 11.8 10.4 1.1 1 0 0 1 1 1 0 AAA domain Bap31_Bap29_C PF18035.1 CBY10125.1 - 0.084 12.9 0.5 0.084 12.9 0.5 2.1 3 0 0 3 3 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain MIS13 PF08202.11 CBY10125.1 - 0.11 11.8 10.4 0.074 12.3 9.1 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family MYO10_CC PF16735.5 CBY10125.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.9 2 2 1 3 3 3 0 Unconventional myosin-X coiled coil domain TEX13 PF15186.6 CBY10125.1 - 0.21 11.3 7.9 0.31 10.7 7.9 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family T3SS_needle_F PF09392.10 CBY10125.1 - 0.24 11.6 7.1 0.32 11.2 0.3 3.2 2 1 1 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Tweety PF04906.13 CBY10125.1 - 0.28 9.8 6.0 0.38 9.4 4.9 1.6 1 1 1 2 2 2 0 Tweety DUF1664 PF07889.12 CBY10125.1 - 0.32 11.0 8.5 0.21 11.6 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CBY10125.1 - 0.36 10.9 9.5 0.3 11.1 7.6 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 CBY10125.1 - 0.43 11.0 11.1 0.79 10.2 2.3 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4988 PF16378.5 CBY10125.1 - 0.55 9.9 4.7 2 8.1 1.3 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF2703 PF10865.8 CBY10125.1 - 0.83 9.8 3.6 1.8 8.8 0.5 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2703) Exonuc_VII_L PF02601.15 CBY10125.1 - 1.6 8.2 9.2 1.9 8.0 9.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit hDGE_amylase PF14701.6 CBY10125.1 - 1.9 7.4 7.1 2.3 7.2 7.1 1.0 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain UPF0242 PF06785.11 CBY10125.1 - 2 8.5 16.5 7 6.7 3.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 CBY10125.1 - 3 8.4 11.0 4.7 7.8 1.9 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CLZ PF16526.5 CBY10125.1 - 3.1 8.2 9.6 1.1 9.7 0.9 3.0 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 CBY10125.1 - 3.4 8.0 8.2 45 4.4 6.4 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Allexi_40kDa PF05549.11 CBY10125.1 - 4.6 6.7 9.2 11 5.5 6.3 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein EAP30 PF04157.16 CBY10125.1 - 4.9 6.4 8.6 41 3.3 8.5 2.1 1 1 0 1 1 1 0 EAP30/Vps36 family Prominin PF05478.11 CBY10125.1 - 6.9 4.5 11.5 2.9 5.7 4.5 1.4 1 1 1 2 2 2 0 Prominin Matrilin_ccoil PF10393.9 CBY10125.1 - 7.6 6.5 10.9 0.86 9.5 1.0 3.1 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Atg14 PF10186.9 CBY10125.1 - 7.9 5.5 12.4 4.9 6.2 2.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ada3 PF10198.9 CBY10125.1 - 8 6.6 11.3 0.27 11.4 3.3 2.3 2 1 0 2 2 2 0 Histone acetyltransferases subunit 3 SlyX PF04102.12 CBY10125.1 - 9.4 6.9 14.3 9.9 6.9 0.7 3.2 2 1 1 3 3 3 0 SlyX PARP PF00644.20 CBY10126.1 - 2.3e-61 206.8 1.1 1.5e-30 106.2 0.1 3.2 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CBY10126.1 - 2.4e-29 102.2 1.5 2.4e-29 102.2 1.5 2.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain Exotox-A_cataly PF09009.10 CBY10126.1 - 0.0055 16.5 0.1 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 Exotoxin A catalytic WGR PF05406.15 CBY10126.1 - 0.01 15.9 0.8 0.033 14.3 0.8 2.0 1 1 0 1 1 1 0 WGR domain TSC22 PF01166.18 CBY10126.1 - 2.6 8.4 16.8 2.6 8.4 0.6 5.2 3 2 2 5 5 5 0 TSC-22/dip/bun family BCDHK_Adom3 PF10436.9 CBY10127.1 - 8e-17 61.5 0.5 1.3e-16 60.9 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBY10127.1 - 7e-10 39.4 0.0 2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBY10127.1 - 1.7e-05 24.7 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 CBY10127.1 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain LRR_4 PF12799.7 CBY10128.1 - 0.00023 21.5 4.6 0.99 9.9 0.9 4.0 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) zf-C2H2 PF00096.26 CBY10130.1 - 0.00081 19.7 1.5 0.00081 19.7 1.5 6.4 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY10130.1 - 0.0027 18.1 23.8 0.0047 17.3 4.4 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY10130.1 - 0.014 16.2 34.5 0.021 15.6 1.3 6.7 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY10130.1 - 0.57 10.0 4.6 7.1 6.5 0.9 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 CBY10130.1 - 1 9.2 18.1 0.1 12.4 3.6 4.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-Mss51 PF13824.6 CBY10130.1 - 2.1 8.5 8.1 5.7 7.1 0.1 3.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Cpn60_TCP1 PF00118.24 CBY10131.1 - 2.6e-162 540.9 5.9 2.9e-162 540.7 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GCD14 PF08704.10 CBY10132.1 - 5.5e-91 304.6 0.0 1.2e-90 303.5 0.0 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CBY10132.1 - 2.1e-11 43.8 0.0 3.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY10132.1 - 8.6e-06 26.4 0.0 1.8e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Gcd10p PF04189.13 CBY10132.1 - 0.00042 19.5 0.1 0.00072 18.8 0.1 1.3 1 0 0 1 1 1 1 Gcd10p family Methyltransf_24 PF13578.6 CBY10132.1 - 0.0016 19.5 0.0 0.003 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 CBY10132.1 - 0.0038 17.0 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 CBY10132.1 - 0.0048 16.7 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 CBY10132.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TBCC PF07986.12 CBY10133.1 - 1.6e-26 92.4 2.2 2.6e-26 91.7 2.2 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 CBY10133.1 - 6.2e-05 22.7 2.5 0.00011 21.9 2.5 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Transcrip_act PF04949.13 CBY10134.1 - 4.2e-08 33.2 24.1 4.2e-08 33.2 24.1 2.7 1 1 1 2 2 2 1 Transcriptional activator C2-set_2 PF08205.12 CBY10135.1 - 0.014 15.4 0.2 0.79 9.8 0.1 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Acatn PF13000.7 CBY10139.1 - 9.1e-95 318.2 28.2 5.6e-65 219.9 12.9 4.8 1 1 3 4 4 4 4 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 CBY10139.1 - 0.2 10.5 13.2 0.71 8.7 13.2 1.8 1 1 0 1 1 1 0 MFS_1 like family 4HBT PF03061.22 CBY10140.1 - 1.2e-05 25.6 0.0 2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CBY10140.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily zf-H2C2_2 PF13465.6 CBY10141.1 - 5.5e-05 23.4 26.1 0.0095 16.3 0.2 6.4 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY10141.1 - 5.5e-05 23.4 44.3 0.016 15.6 0.8 7.2 6 1 1 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY10141.1 - 0.002 18.4 0.1 0.002 18.4 0.1 4.6 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY10141.1 - 0.0076 16.2 24.2 0.14 12.2 0.3 5.1 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY10141.1 - 0.28 11.0 22.4 0.083 12.7 2.9 5.2 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBY10141.1 - 1.1 10.3 41.8 0.63 11.0 0.8 6.8 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY10141.1 - 6.8 6.5 9.7 0.39 10.5 1.4 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type AlbA_2 PF04326.14 CBY10142.1 - 9.6e-12 45.3 0.0 2.4e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Putative DNA-binding domain Sec1 PF00995.23 CBY10143.1 - 2e-21 76.8 0.1 3.4e-21 76.1 0.0 1.3 2 0 0 2 2 2 1 Sec1 family DUF1803 PF08820.10 CBY10143.1 - 0.12 12.4 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) Sec1 PF00995.23 CBY10144.1 - 6.5e-08 32.3 0.3 7.2e-08 32.1 0.3 1.0 1 0 0 1 1 1 1 Sec1 family PIG-S PF10510.9 CBY10147.1 - 1.2e-48 166.2 8.6 1.3e-43 149.6 2.9 2.8 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein HMA PF00403.26 CBY10148.1 - 3.1e-06 27.6 0.5 4.6e-06 27.0 0.5 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain TFIIS_C PF01096.18 CBY10148.1 - 0.082 12.8 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 CBY10148.1 - 0.15 11.8 1.6 0.16 11.7 0.0 1.8 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Prefoldin PF02996.17 CBY10149.1 - 1.8e-10 40.8 1.0 1.8e-10 40.8 1.0 2.5 2 1 1 3 3 3 1 Prefoldin subunit DUF621 PF04789.15 CBY10149.1 - 0.27 10.4 0.0 0.39 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Patched PF02460.18 CBY10149.1 - 0.5 8.4 1.6 0.74 7.8 1.6 1.3 1 0 0 1 1 1 0 Patched family DUF3926 PF13080.6 CBY10149.1 - 2.7 8.0 5.5 2.7 8.0 1.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) CoA_transf_3 PF02515.17 CBY10149.1 - 2.8 7.0 5.3 19 4.3 0.0 2.4 1 1 1 2 2 2 0 CoA-transferase family III Fibrinogen_C PF00147.18 CBY10150.1 - 9.8e-46 156.3 6.2 1.4e-45 155.8 6.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF3829 PF12889.7 CBY10150.1 - 3e-05 23.7 1.4 5.6e-05 22.7 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) RPW8 PF05659.11 CBY10150.1 - 0.018 14.7 3.0 0.037 13.7 1.2 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Cauli_AT PF03233.13 CBY10150.1 - 0.041 13.8 4.9 0.24 11.3 2.6 2.2 1 1 1 2 2 2 0 Aphid transmission protein TMF_TATA_bd PF12325.8 CBY10150.1 - 0.065 13.5 9.2 0.17 12.1 9.2 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 CBY10150.1 - 0.08 13.0 3.6 0.13 12.3 3.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 CBY10150.1 - 0.14 12.4 4.6 0.4 10.9 4.3 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 CBY10150.1 - 0.14 12.7 1.8 0.28 11.8 1.8 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Mucin PF01456.17 CBY10150.1 - 0.15 12.1 3.2 0.24 11.4 3.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1664 PF07889.12 CBY10150.1 - 0.27 11.3 6.2 2.8 8.0 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MPS2 PF17060.5 CBY10150.1 - 0.34 10.1 5.1 0.49 9.6 5.1 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 FliD_N PF02465.18 CBY10150.1 - 0.37 11.5 1.9 0.54 11.0 0.3 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF948 PF06103.11 CBY10150.1 - 0.37 11.1 2.8 1 9.7 0.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 CBY10150.1 - 0.65 9.2 3.6 0.97 8.6 3.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 CBY10150.1 - 0.81 10.2 2.7 11 6.5 0.8 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CP12 PF02672.15 CBY10151.1 - 0.78 10.5 3.7 1.4 9.7 1.0 2.3 2 1 0 2 2 2 0 CP12 domain Foie-gras_1 PF11817.8 CBY10153.1 - 0.064 12.8 0.6 0.23 11.0 0.8 1.6 1 1 1 2 2 2 0 Foie gras liver health family 1 V_ATPase_I PF01496.19 CBY10153.1 - 4.9 5.0 6.5 6.2 4.6 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Homeobox_KN PF05920.11 CBY10154.1 - 1.9e-15 56.5 0.0 4.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY10154.1 - 4.9e-08 32.7 0.9 7.6e-08 32.1 0.9 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CBY10154.1 - 0.02 14.4 0.2 0.77 9.3 0.0 2.3 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez IMPa_N_2 PF18650.1 CBY10154.1 - 0.12 11.7 0.4 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Myosin_tail_1 PF01576.19 CBY10155.1 - 1.1e-20 73.2 33.4 1.2e-20 73.0 33.4 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.20 CBY10155.1 - 0.0058 16.0 28.3 0.18 11.2 6.9 2.8 1 1 1 2 2 2 1 Tropomyosin FH2 PF02181.23 CBY10155.1 - 0.069 12.2 17.2 0.24 10.5 3.5 2.5 1 1 1 2 2 2 0 Formin Homology 2 Domain FlaC_arch PF05377.11 CBY10155.1 - 0.19 12.1 0.6 0.19 12.1 0.6 3.6 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 CBY10155.1 - 0.35 11.0 31.8 0.31 11.2 18.8 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF3135 PF11333.8 CBY10155.1 - 0.44 10.8 0.0 0.44 10.8 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3135) Exonuc_VII_L PF02601.15 CBY10155.1 - 0.64 9.5 17.4 1 8.8 17.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tn7_Tnp_TnsA_C PF08721.11 CBY10155.1 - 0.83 10.3 3.6 3.3 8.4 0.2 2.6 2 1 1 3 3 3 0 TnsA endonuclease C terminal PspB PF06667.12 CBY10155.1 - 0.87 9.7 13.6 1.8 8.7 3.1 2.9 2 1 1 3 3 3 0 Phage shock protein B DUF745 PF05335.13 CBY10155.1 - 0.97 9.1 17.8 0.67 9.7 13.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 CBY10155.1 - 1.1 9.5 15.5 0.83 9.8 9.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 CBY10155.1 - 1.2 9.4 30.1 3.9 7.6 30.1 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) MtrG PF04210.13 CBY10155.1 - 2.1 8.3 6.0 2.1 8.3 0.0 3.2 3 1 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G ALMT PF11744.8 CBY10155.1 - 2.6 6.8 17.1 3.2 6.5 17.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3573 PF12097.8 CBY10155.1 - 3.2 6.5 5.9 7.7 5.2 5.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) CorA PF01544.18 CBY10155.1 - 3.6 6.8 10.7 8.3 5.6 10.6 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Lebercilin PF15619.6 CBY10155.1 - 3.6 7.2 34.0 1.7 8.3 25.1 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Leu_zip PF15294.6 CBY10155.1 - 5 6.6 24.0 13 5.2 24.0 1.6 1 1 0 1 1 1 0 Leucine zipper ISG65-75 PF11727.8 CBY10155.1 - 5.1 6.2 20.6 0.26 10.5 10.8 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein Zein-binding PF04576.15 CBY10155.1 - 5.4 7.4 24.4 0.11 12.8 9.1 3.6 1 1 3 4 4 4 0 Zein-binding Allexi_40kDa PF05549.11 CBY10155.1 - 8 5.9 10.8 7.9 5.9 1.2 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Myosin_head PF00063.21 CBY10156.1 - 3.8e-262 871.4 1.5 3.8e-262 871.4 1.5 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY10156.1 - 6.9e-122 408.3 203.9 9.2e-122 407.9 203.9 1.0 1 0 0 1 1 1 1 Myosin tail DUF4250 PF14056.6 CBY10156.1 - 0.039 13.9 0.3 0.039 13.9 0.3 5.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4250) Myosin_N PF02736.19 CBY10156.1 - 0.073 12.9 1.1 0.28 11.1 1.1 2.1 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain IQ PF00612.27 CBY10156.1 - 0.12 12.2 0.0 0.41 10.6 0.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY10156.1 - 0.14 12.4 0.0 0.14 12.4 0.0 4.8 6 0 0 6 6 6 0 AAA domain AAA_16 PF13191.6 CBY10156.1 - 0.37 11.2 0.0 0.37 11.2 0.0 6.6 2 1 1 4 4 4 0 AAA ATPase domain HSBP1 PF06825.12 CBY10156.1 - 5.4 7.0 19.7 0.58 10.0 0.4 6.0 6 0 0 6 6 6 0 Heat shock factor binding protein 1 Filament PF00038.21 CBY10156.1 - 6.7 6.2 177.1 0.22 11.1 28.2 6.6 1 1 4 5 5 5 0 Intermediate filament protein Phospholip_A2_1 PF00068.19 CBY10157.1 - 5.5e-17 62.3 11.2 9.9e-17 61.4 11.2 1.4 1 0 0 1 1 1 1 Phospholipase A2 DUF3752 PF12572.8 CBY10160.1 - 0.018 15.6 5.9 0.018 15.6 5.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) CDC27 PF09507.10 CBY10161.1 - 1.9 7.8 14.1 2.8 7.2 14.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EF-hand_1 PF00036.32 CBY10162.1 - 6.2e-21 72.3 7.0 0.0006 19.2 0.3 5.9 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.6 CBY10162.1 - 1e-17 62.7 5.3 0.00052 19.4 0.0 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY10162.1 - 1.7e-15 55.6 9.3 0.029 14.3 0.0 5.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CBY10162.1 - 1.9e-15 57.1 19.2 1e-09 38.7 0.5 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CBY10162.1 - 5.2e-07 29.4 18.3 0.033 14.0 0.0 5.3 5 1 1 6 6 6 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY10162.1 - 0.0014 19.0 12.9 0.0022 18.3 0.4 3.4 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CBY10162.1 - 0.49 10.3 4.1 10 6.1 0.3 3.5 3 0 0 3 3 3 0 EF hand Dockerin_1 PF00404.18 CBY10162.1 - 1.5 9.0 5.0 5.5 7.3 0.1 3.5 3 1 1 4 4 4 0 Dockerin type I domain EF-hand_4 PF12763.7 CBY10162.1 - 4.3 7.3 13.1 2.6 8.1 0.2 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Abhydrolase_2 PF02230.16 CBY10163.1 - 3.9e-56 190.3 0.0 4.4e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CBY10163.1 - 1.8e-09 37.2 0.0 0.00015 21.1 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CBY10163.1 - 4.3e-07 29.6 0.1 0.033 13.7 0.0 2.5 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 CBY10163.1 - 2.7e-06 27.1 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CBY10163.1 - 5.1e-06 26.3 0.0 2.2e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY10163.1 - 5.6e-06 27.1 0.0 7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CBY10163.1 - 6.9e-06 25.9 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CBY10163.1 - 1.5e-05 24.8 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 CBY10163.1 - 0.0035 17.2 0.0 0.031 14.1 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 CBY10163.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.7 CBY10163.1 - 0.024 13.6 0.0 0.024 13.6 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydro_lipase PF04083.16 CBY10163.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ank_5 PF13857.6 CBY10164.1 - 1.3e-10 41.3 0.0 4.5e-10 39.6 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY10164.1 - 1.9e-10 41.1 0.7 6.2e-05 23.5 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY10164.1 - 3e-08 34.1 0.1 1.1e-07 32.3 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY10164.1 - 4.3e-07 30.1 0.1 9.7e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 CBY10164.1 - 6.8e-07 29.1 0.1 2.4e-06 27.4 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat HTH_ABP1_N PF18107.1 CBY10164.1 - 0.00074 19.2 0.2 0.0019 17.9 0.2 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain Mad3_BUB1_I PF08311.12 CBY10164.1 - 0.039 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Thiolase_N PF00108.23 CBY10165.1 - 9e-90 300.5 5.2 1.4e-89 300.0 5.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY10165.1 - 2.5e-43 146.7 3.4 2.5e-43 146.7 0.3 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY10165.1 - 4.7e-05 23.1 4.4 0.00017 21.2 2.5 2.3 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CBY10165.1 - 7.7 6.5 6.6 15 5.5 0.5 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thioredoxin PF00085.20 CBY10166.1 - 3.7e-09 36.5 0.4 6.4e-09 35.7 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Phosducin PF02114.16 CBY10166.1 - 2e-07 30.3 0.5 2.4e-07 30.0 0.5 1.1 1 0 0 1 1 1 1 Phosducin DUF3037 PF11236.8 CBY10166.1 - 0.089 13.2 0.2 0.15 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) OLF PF02191.16 CBY10167.1 - 6e-70 235.6 1.0 8.4e-70 235.2 1.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Gal_Lectin PF02140.18 CBY10167.1 - 7.3e-18 64.8 2.7 8.1e-17 61.4 0.6 2.8 2 0 0 2 2 2 1 Galactose binding lectin domain 7tm_2 PF00002.24 CBY10167.1 - 1.5e-11 44.1 7.0 2.4e-11 43.4 7.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1084 PF06454.11 CBY10167.1 - 0.097 12.0 1.2 0.2 11.0 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) Pox_E6 PF04656.12 CBY10168.1 - 0.066 11.7 0.0 0.079 11.4 0.0 1.0 1 0 0 1 1 1 0 Pox virus E6 protein SUFU PF05076.13 CBY10168.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) CDT1 PF08839.11 CBY10172.1 - 0.031 14.6 0.9 0.076 13.3 0.9 1.6 1 0 0 1 1 1 0 DNA replication factor CDT1 like DUF1318 PF07027.12 CBY10172.1 - 0.078 13.4 0.1 0.29 11.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) DBC1 PF14443.6 CBY10173.1 - 0.00082 19.3 0.2 0.052 13.5 0.1 2.9 2 0 0 2 2 2 2 DBC1 YabA PF06156.13 CBY10174.1 - 0.33 11.6 7.4 7.1 7.3 0.5 2.8 2 0 0 2 2 2 0 Initiation control protein YabA Na_Ca_ex PF01699.24 CBY10175.1 - 2.5e-35 121.7 39.8 1.4e-18 67.3 15.5 3.1 3 0 0 3 3 3 3 Sodium/calcium exchanger protein PI3K_1B_p101 PF10486.9 CBY10175.1 - 0.061 11.1 0.1 0.085 10.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SSF PF00474.17 CBY10177.1 - 2e-14 53.3 7.8 2.8e-14 52.8 7.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Kri1 PF05178.12 CBY10179.1 - 0.00077 20.0 20.2 0.00077 20.0 20.2 6.3 4 2 1 5 5 5 1 KRI1-like family LIN52 PF10044.9 CBY10179.1 - 0.0076 16.9 4.1 0.61 10.8 1.1 3.4 2 0 0 2 2 2 2 Retinal tissue protein ABC_tran PF00005.27 CBY10183.1 - 3.8e-22 79.3 0.0 9.9e-22 77.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 CBY10183.1 - 1.6e-19 70.2 28.0 2.2e-19 69.8 19.9 2.2 1 1 1 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBY10183.1 - 6.8e-09 35.9 0.1 3.4e-05 23.8 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CBY10183.1 - 7.9e-08 32.9 1.2 0.0044 17.7 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4162) AAA_23 PF13476.6 CBY10183.1 - 0.22 12.0 1.3 0.56 10.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBY10184.1 - 1.1e-22 81.0 0.1 1.7e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CBY10184.1 - 1e-16 61.0 15.7 1e-16 61.0 15.7 2.2 1 1 1 2 2 2 2 ABC-2 family transporter protein AAA_23 PF13476.6 CBY10184.1 - 0.00034 21.2 0.0 0.00062 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CBY10184.1 - 0.00089 19.0 0.9 0.0021 17.8 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBY10184.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CBY10184.1 - 0.006 16.4 0.1 0.027 14.3 0.1 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 CBY10184.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBY10184.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain DUF5542 PF17696.1 CBY10184.1 - 0.034 14.3 0.1 0.13 12.4 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5542) AAA_15 PF13175.6 CBY10184.1 - 0.038 13.7 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 CBY10184.1 - 0.058 12.8 0.3 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MukB PF04310.12 CBY10184.1 - 0.092 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 MukB N-terminal DUF3099 PF11298.8 CBY10184.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) AAA_30 PF13604.6 CBY10184.1 - 0.19 11.5 0.1 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain SH3BP5 PF05276.14 CBY10185.1 - 1e-29 104.0 14.3 1e-29 104.0 14.3 1.9 2 1 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) YabA PF06156.13 CBY10185.1 - 0.0018 18.9 0.6 0.0018 18.9 0.6 3.2 3 1 0 3 3 3 1 Initiation control protein YabA TPR_MLP1_2 PF07926.12 CBY10185.1 - 0.0094 16.0 1.7 0.0094 16.0 1.7 3.5 3 1 0 3 3 2 1 TPR/MLP1/MLP2-like protein TSC22 PF01166.18 CBY10185.1 - 0.028 14.7 3.3 0.032 14.6 0.6 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family NRBF2 PF08961.10 CBY10185.1 - 0.067 12.8 0.6 0.067 12.8 0.6 2.8 3 1 1 4 4 4 0 Nuclear receptor-binding factor 2, autophagy regulator MR_MLE_N PF02746.16 CBY10185.1 - 0.17 12.1 0.1 8.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DivIC PF04977.15 CBY10185.1 - 0.26 11.1 8.9 0.15 11.9 0.8 3.2 3 1 0 3 3 3 0 Septum formation initiator Myb_DNA-bind_3 PF12776.7 CBY10185.1 - 2.6 9.1 7.1 16 6.6 0.7 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain HALZ PF02183.18 CBY10185.1 - 4.3 7.7 12.8 0.096 12.9 2.4 3.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper Hydrolase_2 PF07486.12 CBY10185.1 - 5.5 7.9 5.8 6 7.8 1.3 2.4 1 1 1 2 2 2 0 Cell Wall Hydrolase SlyX PF04102.12 CBY10185.1 - 9.4 6.9 11.6 0.49 11.0 0.9 3.4 4 0 0 4 4 4 0 SlyX PLN_propep PF16485.5 CBY10186.1 - 0.083 12.6 0.2 0.083 12.6 0.2 1.5 2 0 0 2 2 2 0 Protealysin propeptide DUF1179 PF06678.11 CBY10186.1 - 0.11 12.5 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) p450 PF00067.22 CBY10187.1 - 1.1e-53 182.6 0.1 1.6e-53 182.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 SLC3A2_N PF16028.5 CBY10187.1 - 0.15 11.6 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Recep_L_domain PF01030.24 CBY10189.1 - 0.091 12.9 2.0 0.44 10.7 0.6 2.1 2 0 0 2 2 2 0 Receptor L domain DUF4521 PF15021.6 CBY10190.1 - 0.0016 18.4 0.1 0.0019 18.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4521) DUF4381 PF14316.6 CBY10190.1 - 0.019 15.2 0.0 0.022 15.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TssO PF17561.2 CBY10190.1 - 0.052 13.7 0.1 0.06 13.5 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO CYSTM PF12734.7 CBY10190.1 - 0.23 11.8 1.6 0.62 10.4 1.6 1.6 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Methyltransf_23 PF13489.6 CBY10191.1 - 8.5e-18 64.7 0.0 1.3e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY10191.1 - 2.5e-17 63.4 0.0 5.1e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY10191.1 - 2.4e-16 60.1 0.0 4.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBY10191.1 - 3.1e-16 59.5 0.1 5.2e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CBY10191.1 - 5.3e-14 52.3 0.0 7.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY10191.1 - 4.6e-13 49.7 0.0 1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY10191.1 - 1.3e-12 47.6 0.2 5.1e-12 45.6 0.1 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 CBY10191.1 - 3.1e-09 36.6 0.3 1.1e-07 31.5 0.0 2.8 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain PrmA PF06325.13 CBY10191.1 - 9.4e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CBY10191.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 CBY10191.1 - 0.0034 16.4 0.0 0.0051 15.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 CBY10191.1 - 0.0083 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 CBY10191.1 - 0.011 15.3 0.2 0.027 14.0 0.2 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 CBY10191.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 CBY10191.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MAP65_ASE1 PF03999.12 CBY10191.1 - 0.042 12.6 0.1 0.054 12.2 0.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) UPF0020 PF01170.18 CBY10191.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.26 CBY10191.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Trypsin PF00089.26 CBY10192.1 - 1.8e-46 158.8 0.3 2.2e-46 158.5 0.3 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY10192.1 - 9.3e-06 26.6 0.1 2.3e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY10192.1 - 0.044 13.3 0.0 0.53 9.8 0.0 2.0 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Ank_2 PF12796.7 CBY10193.1 - 4e-21 75.4 0.1 1.2e-11 45.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY10193.1 - 3.5e-20 69.9 0.1 1.1e-05 25.4 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CBY10193.1 - 6.3e-18 64.3 1.6 8.1e-06 26.1 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CBY10193.1 - 1.3e-15 57.2 1.0 9.8e-08 32.1 0.1 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY10193.1 - 4.2e-14 52.7 0.9 1.5e-10 41.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) MFS_1 PF07690.16 CBY10194.1 - 1.8e-58 198.1 22.1 1.8e-58 198.1 22.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY10194.1 - 1.4e-09 37.4 6.7 1.4e-09 37.4 6.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CBY10194.1 - 1.4e-06 27.9 2.1 1.4e-06 27.9 2.1 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 CBY10194.1 - 0.0075 14.9 11.9 0.0065 15.1 2.9 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein BT1 PF03092.16 CBY10194.1 - 0.01 14.1 3.8 0.12 10.5 0.2 2.7 3 0 0 3 3 3 0 BT1 family Cyclin_N PF00134.23 CBY10197.1 - 1.4e-18 66.8 0.6 1.9e-18 66.4 0.6 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.16 CBY10199.1 - 1e-21 77.2 53.7 4.5e-19 68.6 25.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3619 PF12279.8 CBY10199.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) PhoPQ_related PF10142.9 CBY10201.1 - 0.077 11.6 0.1 0.14 10.8 0.1 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein bZIP_1 PF00170.21 CBY10201.1 - 0.14 12.3 8.4 0.22 11.6 1.1 2.7 3 0 0 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.15 CBY10201.1 - 1.6 8.9 7.8 0.53 10.4 1.6 2.7 2 0 0 2 2 2 0 Basic region leucine zipper RVT_1 PF00078.27 CBY10202.1 - 7.9e-31 107.3 0.0 2.6e-30 105.6 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Y2_Tnp PF04986.13 CBY10202.1 - 0.037 14.1 0.0 0.17 12.0 0.0 2.1 1 0 0 1 1 1 0 Putative transposase RVT_1 PF00078.27 CBY10203.1 - 4.5e-07 29.6 0.5 0.00018 21.1 0.5 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 CBY10203.1 - 4.3e-05 23.7 0.2 0.02 15.2 0.0 3.6 2 1 0 2 2 2 1 GIY-YIG catalytic domain Rsbr_N PF08678.10 CBY10203.1 - 0.015 15.4 0.0 0.073 13.1 0.0 2.1 2 0 0 2 2 2 0 Rsbr N terminal Lipocalin_7 PF14651.6 CBY10204.1 - 0.03 14.2 1.0 0.06 13.3 1.0 1.5 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family IMUP PF15761.5 CBY10205.1 - 0.015 16.0 5.3 0.027 15.2 5.3 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF755 PF05501.11 CBY10205.1 - 2.3 8.5 14.2 4.2 7.7 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2457 PF10446.9 CBY10205.1 - 2.5 7.1 13.4 3.4 6.7 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Actin PF00022.19 CBY10206.1 - 4.3e-147 490.0 0.0 1.4e-146 488.3 0.0 1.7 1 1 0 1 1 1 1 Actin IDO PF01231.18 CBY10208.1 - 1.4e-96 324.0 0.1 1.7e-96 323.7 0.1 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PhoPQ_related PF10142.9 CBY10209.1 - 3.1e-99 332.1 0.3 4e-99 331.7 0.3 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein MFS_1 PF07690.16 CBY10211.1 - 2.1e-11 43.3 38.0 6.3e-10 38.5 30.6 3.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CBY10211.1 - 1.6e-09 36.9 34.4 6.2e-07 28.3 16.5 3.3 2 2 0 2 2 2 2 MFS/sugar transport protein SelR PF01641.18 CBY10212.1 - 3.1e-38 130.6 0.6 4.1e-38 130.2 0.6 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 CBY10212.1 - 0.00066 19.9 1.1 0.0019 18.4 1.1 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ta0938 PF11494.8 CBY10212.1 - 0.11 12.8 1.3 0.4 11.0 0.2 2.1 1 1 1 2 2 2 0 Ta0938 GFA PF04828.14 CBY10212.1 - 0.16 12.3 2.9 0.64 10.4 1.9 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 CBY10212.1 - 1.7 8.8 6.5 4.1 7.7 0.1 2.9 3 1 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Trypsin PF00089.26 CBY10213.1 - 2.1e-52 178.1 0.6 3.7e-52 177.3 0.6 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY10213.1 - 1.4e-06 29.3 0.0 3.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Coiled-coil_56 PF09813.9 CBY10215.1 - 0.0029 17.6 0.0 0.0052 16.8 0.0 1.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 Glycos_transf_2 PF00535.26 CBY10217.1 - 5.8e-15 55.5 0.0 9.7e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBY10217.1 - 0.049 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Histone PF00125.24 CBY10218.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY10218.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY10218.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY10218.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY10218.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Trypsin PF00089.26 CBY10219.1 - 1.8e-108 361.5 1.2 7.4e-59 199.2 0.1 2.1 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CBY10219.1 - 7.2e-13 49.7 0.0 3.9e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY10219.1 - 6.7e-07 29.7 0.0 0.0011 19.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Lectin_C PF00059.21 CBY10220.1 - 0.00099 19.8 4.5 0.0056 17.4 2.9 2.3 2 0 0 2 2 2 1 Lectin C-type domain 7tm_1 PF00001.21 CBY10222.1 - 0.00019 20.9 0.8 0.00028 20.3 0.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Spo7 PF03907.13 CBY10222.1 - 0.098 12.1 0.5 0.13 11.7 0.5 1.2 1 0 0 1 1 1 0 Spo7-like protein DHHC PF01529.20 CBY10224.1 - 3.2e-37 127.6 11.3 3.2e-37 127.6 11.3 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Imm17 PF15562.6 CBY10224.1 - 0.019 14.8 0.1 0.019 14.8 0.1 2.7 3 0 0 3 3 3 0 Immunity protein 17 DUF4131 PF13567.6 CBY10224.1 - 0.28 10.8 1.6 2.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) OppC_N PF12911.7 CBY10224.1 - 0.53 10.3 5.4 7.4 6.6 0.1 2.7 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Caskin-tail PF16632.5 CBY10225.1 - 0.16 12.4 5.2 3.7 8.0 0.8 4.0 2 1 0 2 2 2 0 C-terminal region of Caskin TPT PF03151.16 CBY10226.1 - 4e-20 72.4 16.3 4.8e-20 72.1 16.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY10226.1 - 1.4e-08 35.0 23.6 0.00013 22.1 6.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CBY10226.1 - 8.5e-07 28.5 18.4 1.1e-06 28.1 18.4 1.2 1 0 0 1 1 1 1 UAA transporter family Peptidase_A8 PF01252.18 CBY10226.1 - 6.6e-05 23.2 2.5 6.6e-05 23.2 2.5 2.7 2 1 1 3 3 3 1 Signal peptidase (SPase) II SLC35F PF06027.12 CBY10226.1 - 0.0076 15.8 12.6 0.2 11.2 0.2 2.5 2 1 1 3 3 3 2 Solute carrier family 35 Phage_holin_3_3 PF16083.5 CBY10226.1 - 0.011 15.8 2.5 0.089 12.9 0.7 2.6 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III EF-hand_7 PF13499.6 CBY10228.1 - 1.6e-11 44.5 8.4 6.2e-07 29.8 1.8 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY10228.1 - 3.2e-09 36.0 7.4 1.2e-05 24.9 0.9 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CBY10228.1 - 1.4e-07 30.6 14.8 4.2e-05 22.8 2.2 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY10228.1 - 1.2e-06 28.3 15.8 0.024 14.5 1.6 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CBY10228.1 - 0.0011 18.3 2.2 0.0011 18.3 2.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 CBY10228.1 - 0.017 15.1 0.7 0.19 11.7 0.1 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY10228.1 - 0.31 11.4 1.8 1.7 9.0 0.3 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Sulfotransfer_2 PF03567.14 CBY10229.1 - 2.4e-41 142.3 1.3 3.1e-41 142.0 1.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family SH2 PF00017.24 CBY10231.1 - 1.6e-05 24.9 0.0 3.7e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 SH2 domain Wtap PF17098.5 CBY10231.1 - 0.06 13.3 0.1 0.069 13.1 0.1 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family Cbl_N3 PF02762.14 CBY10231.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain LRR_8 PF13855.6 CBY10232.1 - 1.3e-13 50.5 2.4 4.2e-06 26.4 0.2 3.2 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY10232.1 - 1.5e-10 41.2 5.0 3.2e-05 24.2 0.2 4.0 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY10232.1 - 2.1e-07 30.9 0.1 3.1e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY10232.1 - 0.009 15.5 1.2 0.069 12.7 0.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CBY10232.1 - 0.027 15.0 2.4 6.8 7.7 1.1 4.2 2 1 0 2 2 2 0 Leucine Rich Repeat Mucin PF01456.17 CBY10233.1 - 0.81 9.7 12.0 4.2 7.4 3.0 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein R3H-assoc PF13902.6 CBY10233.1 - 8.8 6.7 6.8 27 5.2 6.8 1.9 1 1 0 1 1 1 0 R3H-associated N-terminal domain Sulfotransfer_1 PF00685.27 CBY10234.1 - 9.3e-05 22.0 0.1 0.00012 21.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY10234.1 - 0.0021 18.5 0.0 0.0032 17.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family IFT46_B_C PF12317.8 CBY10235.1 - 0.047 13.4 1.6 0.29 10.8 0.8 2.4 2 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal MT PF12777.7 CBY10235.1 - 0.055 12.5 0.5 1.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor Med29 PF11568.8 CBY10236.1 - 0.0028 17.9 2.2 0.0059 16.8 2.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit 29 Choline_kinase PF01633.20 CBY10237.1 - 2.1e-08 34.0 0.2 5.4e-08 32.7 0.2 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY10237.1 - 1.8e-06 28.1 0.6 3e-06 27.3 0.6 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY10237.1 - 0.00012 21.5 0.4 0.00019 20.8 0.4 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase EGF_CA PF07645.15 CBY10238.1 - 1.5e-26 92.3 108.6 8.6e-07 29.1 5.5 7.5 7 0 0 7 7 7 5 Calcium-binding EGF domain EGF_3 PF12947.7 CBY10238.1 - 1.2e-07 31.8 82.9 0.00044 20.4 6.8 7.5 7 0 0 7 7 7 4 EGF domain cEGF PF12662.7 CBY10238.1 - 9.6e-06 25.4 15.2 3.8e-05 23.5 2.2 6.6 7 0 0 7 7 7 3 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CBY10238.1 - 0.0038 17.5 8.8 0.0038 17.5 8.8 7.2 6 1 1 7 7 7 3 Pvs28 EGF domain FXa_inhibition PF14670.6 CBY10238.1 - 0.0056 16.9 5.7 0.0056 16.9 5.7 7.3 7 0 0 7 7 7 2 Coagulation Factor Xa inhibitory site DUF5373 PF17343.2 CBY10238.1 - 0.44 10.4 6.3 1.1 9.1 6.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5373) EGF PF00008.27 CBY10238.1 - 1.7 9.0 83.1 0.51 10.7 5.9 7.1 6 0 0 6 6 6 0 EGF-like domain PH PF00169.29 CBY10239.1 - 9.6e-07 29.3 0.2 1.3e-06 28.9 0.2 1.2 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 CBY10240.1 - 1.1e-20 74.7 0.1 1.1e-20 74.7 0.1 2.0 2 1 0 2 2 2 1 RhoGEF domain GLYCAM-1 PF05242.11 CBY10240.1 - 0.047 13.8 3.8 0.079 13.1 3.8 1.5 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Rubrerythrin PF02915.17 CBY10240.1 - 0.18 12.2 1.0 0.34 11.3 0.2 1.8 2 0 0 2 2 2 0 Rubrerythrin SR-25 PF10500.9 CBY10240.1 - 8 6.0 14.7 13 5.4 14.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Prenyltrans PF00432.21 CBY10241.1 - 0.0035 17.1 0.7 0.0094 15.7 0.7 1.9 1 1 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat Steroid_dh PF02544.16 CBY10242.1 - 1.7e-14 54.1 6.3 3.6e-14 53.0 6.3 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase S_100 PF01023.19 CBY10242.1 - 0.12 12.1 0.0 0.38 10.5 0.0 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain N_formyltrans_C PF18216.1 CBY10242.1 - 0.14 11.9 0.0 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 N-formyltransferase dimerization C-terminal domain Alk_phosphatase PF00245.20 CBY10243.1 - 4.5e-89 299.3 0.0 5.6e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CBY10243.1 - 0.00018 21.0 0.1 0.00027 20.4 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Glyco_transf_10 PF00852.19 CBY10244.1 - 2.4e-45 154.4 0.6 3.2e-45 154.0 0.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY10244.1 - 0.0026 18.2 0.1 0.0052 17.2 0.1 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Tim54 PF11711.8 CBY10245.1 - 0.018 13.8 5.3 0.023 13.5 5.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Borrelia_P83 PF05262.11 CBY10245.1 - 0.028 12.9 5.9 0.035 12.6 5.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR3 PF03666.13 CBY10245.1 - 0.036 12.9 3.0 0.049 12.4 3.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HSP90 PF00183.18 CBY10245.1 - 0.12 11.3 8.0 0.19 10.6 8.0 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF4512 PF14975.6 CBY10245.1 - 0.12 13.2 1.1 0.3 11.9 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) RR_TM4-6 PF06459.12 CBY10245.1 - 0.22 11.3 7.5 0.33 10.7 7.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 CBY10245.1 - 0.24 11.8 4.1 0.39 11.1 4.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sulfotransfer_1 PF00685.27 CBY10248.1 - 1.2e-17 64.3 0.3 2.1e-17 63.5 0.3 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY10248.1 - 1.9e-05 25.2 0.2 0.037 14.4 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY10249.1 - 1.2e-11 44.7 0.0 1.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain LMF1 PF06762.14 CBY10250.1 - 1.3e-106 357.4 1.5 1.8e-106 356.9 1.5 1.2 1 0 0 1 1 1 1 Lipase maturation factor MerC PF03203.14 CBY10250.1 - 1.6 9.2 0.0 1.6 9.2 0.0 3.0 2 1 0 2 2 2 0 MerC mercury resistance protein Ivy PF08816.11 CBY10251.1 - 0.087 13.0 4.3 3.1 8.0 0.2 2.1 1 1 1 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) DUF5057 PF16480.5 CBY10252.1 - 0.055 12.8 0.1 0.083 12.2 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5057) Amnionless PF14828.6 CBY10252.1 - 0.074 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Amnionless Amnionless PF14828.6 CBY10253.1 - 6.8e-15 54.8 5.0 8e-15 54.6 5.0 1.0 1 0 0 1 1 1 1 Amnionless Tweety PF04906.13 CBY10256.1 - 0.023 13.4 0.6 0.039 12.6 0.6 1.4 1 0 0 1 1 1 0 Tweety O-FucT PF10250.9 CBY10259.1 - 3.2e-09 37.0 0.9 6.3e-08 32.7 0.9 2.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Asp PF00026.23 CBY10260.1 - 1.5e-32 113.3 0.0 1.7e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.23 CBY10261.1 - 4.5e-19 69.0 0.1 5.4e-19 68.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CBY10261.1 - 0.0015 18.8 0.0 0.0019 18.4 0.0 1.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal PAX PF00292.18 CBY10262.1 - 5.7e-58 194.3 0.4 1.1e-57 193.4 0.4 1.5 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CBY10262.1 - 1.1e-23 82.8 1.4 1.8e-23 82.1 1.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY10262.1 - 2.6e-05 24.0 0.1 8.4e-05 22.4 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 CBY10262.1 - 0.00016 21.3 1.0 0.012 15.4 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 CBY10262.1 - 0.016 15.3 0.5 0.51 10.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 CBY10262.1 - 0.062 13.3 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_31 PF13560.6 CBY10262.1 - 0.064 13.6 0.7 2 8.8 0.3 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain MRP-L20 PF12824.7 CBY10262.1 - 0.12 12.5 0.2 0.12 12.5 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 adh_short PF00106.25 CBY10263.1 - 3.4e-28 98.4 0.0 5.8e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY10263.1 - 1.4e-23 83.7 0.1 5.6e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY10263.1 - 1.8e-09 37.8 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Sulfotransfer_2 PF03567.14 CBY10263.1 - 7.5e-06 26.0 0.1 1.1e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family NmrA PF05368.13 CBY10263.1 - 0.00092 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Arg_repressor PF01316.21 CBY10263.1 - 0.067 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain DUF4473 PF14747.6 CBY10265.1 - 0.018 15.6 1.7 0.066 13.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) NPCC PF08058.11 CBY10266.1 - 1.7 8.7 3.4 1.7 8.7 1.3 2.0 2 0 0 2 2 2 0 Nuclear pore complex component Laminin_N PF00055.17 CBY10267.1 - 4.8e-61 206.3 0.1 4.8e-61 206.3 0.1 2.7 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CBY10267.1 - 6e-18 64.7 65.1 6.3e-06 26.2 18.1 4.4 3 1 0 3 3 3 3 Laminin EGF domain F5_F8_type_C PF00754.25 CBY10267.1 - 2.5e-05 24.4 1.4 7.9e-05 22.8 0.1 2.6 3 0 0 3 3 3 1 F5/8 type C domain Laminin_G_2 PF02210.24 CBY10267.1 - 0.028 15.0 0.1 0.098 13.2 0.1 2.0 1 0 0 1 1 1 0 Laminin G domain TIG_2 PF18020.1 CBY10267.1 - 0.069 13.8 1.5 0.2 12.3 1.5 1.8 1 0 0 1 1 1 0 TIG domain found in plexin Septin PF00735.18 CBY10268.1 - 1.4e-127 424.8 0.1 1.8e-127 424.4 0.1 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CBY10268.1 - 3.2e-08 33.6 0.0 9.1e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY10268.1 - 3.3e-07 30.4 0.3 4e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CBY10268.1 - 2.9e-06 26.9 0.1 0.017 14.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CBY10268.1 - 5e-05 22.7 0.0 0.00013 21.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CBY10268.1 - 0.00039 20.5 1.1 0.17 12.0 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.6 CBY10268.1 - 0.0022 18.2 0.2 0.013 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain Ras PF00071.22 CBY10268.1 - 0.0024 17.5 0.1 0.0097 15.5 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CBY10268.1 - 0.0033 17.6 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CBY10268.1 - 0.0051 17.3 0.1 0.03 14.8 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 CBY10268.1 - 0.0066 16.8 0.0 0.016 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBY10268.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY10268.1 - 0.052 14.0 0.6 0.2 12.1 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY10268.1 - 0.088 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 CBY10268.1 - 0.13 11.6 0.4 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region CS PF04969.16 CBY10269.1 - 2.7e-07 31.5 0.5 2.7e-07 31.5 0.5 2.3 2 0 0 2 2 2 1 CS domain TPR_11 PF13414.6 CBY10269.1 - 3.4e-05 23.4 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 CBY10269.1 - 4.1e-05 23.4 1.7 0.075 13.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY10269.1 - 6.3e-05 23.5 0.2 0.0044 17.6 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY10269.1 - 0.00057 19.6 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY10269.1 - 0.00093 19.8 0.1 0.99 10.4 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY10269.1 - 0.038 14.2 0.0 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SOBP PF15279.6 CBY10269.1 - 0.29 11.7 5.9 0.4 11.3 5.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PAS_6 PF08348.11 CBY10269.1 - 0.59 10.0 3.2 4.2 7.3 0.0 3.0 2 1 1 3 3 3 0 YheO-like PAS domain Kinesin PF00225.23 CBY10271.1 - 1.9e-84 283.4 0.0 1.9e-84 283.4 0.0 3.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY10271.1 - 3.2e-21 75.8 0.1 1.2e-18 67.5 0.0 3.5 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 CBY10271.1 - 0.0027 16.6 16.8 0.0027 16.6 16.8 6.2 2 2 5 7 7 7 4 Spc7 kinetochore protein I-set PF07679.16 CBY10271.1 - 0.12 12.5 0.1 0.44 10.7 0.1 2.0 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-SNARE_C PF12352.8 CBY10271.1 - 0.3 11.4 6.6 1.2 9.5 1.0 3.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF3287 PF11690.8 CBY10271.1 - 1.8 8.3 5.0 3 7.6 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) PilJ PF13675.6 CBY10271.1 - 4.3 7.4 16.8 1.1 9.3 2.0 5.0 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term HEAT_2 PF13646.6 CBY10272.1 - 8.5e-06 26.1 0.0 0.018 15.4 0.0 3.4 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 CBY10272.1 - 1.5e-05 24.9 0.1 0.78 10.2 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat Baculo_LEF-2 PF03041.14 CBY10272.1 - 0.031 13.9 0.3 0.24 11.0 0.1 2.5 2 1 0 2 2 2 0 lef-2 SF-assemblin PF06705.11 CBY10272.1 - 0.11 11.9 3.3 2 7.7 0.3 2.5 2 0 0 2 2 2 0 SF-assemblin/beta giardin zf-C3HC4_4 PF15227.6 CBY10273.1 - 1.8e-07 31.2 13.7 3.1e-07 30.4 13.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBY10273.1 - 1.1e-06 28.4 9.6 1.9e-06 27.6 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY10273.1 - 1.4e-06 28.5 12.9 2.4e-06 27.8 12.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY10273.1 - 2.4e-06 27.3 13.5 3.9e-06 26.6 13.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY10273.1 - 4.4e-06 26.5 14.0 7.4e-06 25.7 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY10273.1 - 1.1e-05 25.3 11.5 2.4e-05 24.3 11.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY10273.1 - 0.0089 16.0 14.0 0.046 13.7 14.5 1.9 1 1 1 2 2 2 1 zinc-RING finger domain U-box PF04564.15 CBY10273.1 - 0.018 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 CBY10273.1 - 0.045 13.6 9.6 0.08 12.8 9.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CBY10273.1 - 0.092 12.6 15.2 1.9 8.4 15.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBY10273.1 - 0.17 11.8 3.5 0.27 11.1 3.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-H2C2_2 PF13465.6 CBY10273.1 - 0.2 12.1 14.8 0.71 10.4 2.6 3.1 2 1 1 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 CBY10273.1 - 0.26 11.6 0.3 0.26 11.6 0.3 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 CBY10273.1 - 5.8 7.0 12.3 12 6.0 5.6 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-TAZ PF02135.16 CBY10274.1 - 0.33 11.4 7.3 0.55 10.7 7.3 1.4 1 0 0 1 1 1 0 TAZ zinc finger Methyltransf_28 PF02636.17 CBY10275.1 - 1e-61 208.9 0.0 1.2e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PSP1 PF04468.12 CBY10277.1 - 0.066 13.5 0.3 0.23 11.8 0.3 1.9 1 0 0 1 1 1 0 PSP1 C-terminal conserved region ING PF12998.7 CBY10278.1 - 1.6e-23 83.2 4.6 2.1e-23 82.8 4.6 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CBY10278.1 - 1.8e-05 24.5 8.2 3.2e-05 23.7 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY10278.1 - 0.0066 16.0 2.8 0.012 15.1 2.8 1.5 1 0 0 1 1 1 1 PHD-finger Nup54 PF13874.6 CBY10278.1 - 0.011 15.9 0.6 0.015 15.4 0.6 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3160 PF11369.8 CBY10278.1 - 0.025 13.1 1.9 0.033 12.7 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) THDPS_N_2 PF14805.6 CBY10278.1 - 0.038 14.2 0.4 0.11 12.8 0.1 1.9 2 1 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Muted PF14942.6 CBY10278.1 - 0.069 13.5 6.9 0.099 13.0 6.9 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF724 PF05266.14 CBY10278.1 - 0.12 12.2 5.5 0.16 11.8 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 CBY10278.1 - 0.16 12.2 4.5 1 9.5 5.2 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tho2 PF11262.8 CBY10278.1 - 0.19 10.9 4.3 0.24 10.6 4.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-HC5HC2H PF13771.6 CBY10278.1 - 0.36 11.1 4.6 0.1 12.9 1.1 2.0 2 1 0 2 2 2 0 PHD-like zinc-binding domain DUF4164 PF13747.6 CBY10278.1 - 0.59 10.5 6.5 5 7.5 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TMPIT PF07851.13 CBY10278.1 - 0.68 9.1 6.2 0.96 8.6 6.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-C4pol PF14260.6 CBY10278.1 - 3.4 8.2 8.5 0.75 10.3 0.9 3.0 3 1 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DEAD PF00270.29 CBY10279.1 - 3.6e-38 131.1 0.0 7.6e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY10279.1 - 1.2e-25 90.0 0.2 6.8e-24 84.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY10279.1 - 2.7e-09 37.3 0.0 7e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBY10279.1 - 1.2e-05 25.6 0.7 0.00013 22.3 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY10279.1 - 0.0017 18.7 0.0 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 CBY10279.1 - 0.013 14.3 0.0 3.2 6.4 0.0 3.0 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SNF2_N PF00176.23 CBY10279.1 - 0.044 12.5 0.2 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 SNF2 family N-terminal domain Flavi_DEAD PF07652.14 CBY10279.1 - 0.05 13.6 0.5 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain MoCF_biosynth PF00994.24 CBY10280.1 - 1.1e-52 177.5 0.1 1.6e-25 89.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 CBY10280.1 - 4.6e-39 133.7 0.1 1.7e-38 131.8 0.1 2.0 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 CBY10280.1 - 3.1e-12 46.5 0.0 6.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) zf-MYND PF01753.18 CBY10281.1 - 0.00012 22.1 15.1 0.00012 22.1 15.1 2.9 2 0 0 2 2 2 1 MYND finger PHD PF00628.29 CBY10281.1 - 0.00065 19.5 10.7 0.00065 19.5 10.7 2.9 2 0 0 2 2 2 1 PHD-finger Bromodomain PF00439.25 CBY10281.1 - 0.015 15.4 0.1 0.04 14.0 0.1 1.8 1 0 0 1 1 1 0 Bromodomain ERCC3_RAD25_C PF16203.5 CBY10281.1 - 0.032 13.4 0.0 0.068 12.4 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Ilm1 PF10311.9 CBY10281.1 - 0.13 11.9 0.1 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 DUF4094 PF13334.6 CBY10281.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Zf_RING PF16744.5 CBY10281.1 - 0.73 10.0 22.4 0.071 13.2 7.8 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger AAA PF00004.29 CBY10282.1 - 1e-43 149.0 0.0 3.5e-43 147.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 CBY10282.1 - 6.1e-28 98.0 2.8 1.8e-27 96.5 2.8 1.7 1 1 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 CBY10282.1 - 2e-10 40.3 0.0 4.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBY10282.1 - 6.6e-05 23.4 0.0 0.018 15.5 0.1 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 CBY10282.1 - 0.00013 21.9 0.2 0.0073 16.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CBY10282.1 - 0.00016 21.0 0.0 0.00029 20.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CBY10282.1 - 0.00018 21.3 0.0 0.00053 19.8 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBY10282.1 - 0.0003 21.3 0.8 0.0021 18.6 0.0 2.8 4 0 0 4 4 4 1 AAA domain AAA_2 PF07724.14 CBY10282.1 - 0.00032 20.8 0.0 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CBY10282.1 - 0.011 15.5 0.4 0.087 12.6 0.1 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBY10282.1 - 0.012 15.0 0.2 0.026 13.9 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CBY10282.1 - 0.013 15.5 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CBY10282.1 - 0.015 15.5 0.5 0.8 10.0 0.1 3.3 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.6 CBY10282.1 - 0.025 15.0 0.5 0.12 12.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CBY10282.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 CBY10282.1 - 0.083 12.6 0.0 0.31 10.7 0.0 1.9 1 1 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 CBY10282.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mtc PF03820.17 CBY10283.1 - 3.4e-96 322.0 1.0 3.8e-96 321.8 1.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF3313 PF11769.8 CBY10283.1 - 0.15 11.9 0.3 0.34 10.7 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3313) Ost5 PF05251.12 CBY10283.1 - 0.29 11.4 4.2 0.12 12.6 1.0 2.0 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 AA_permease_2 PF13520.6 CBY10283.1 - 0.39 9.5 7.2 0.18 10.6 5.1 1.4 1 1 0 1 1 1 0 Amino acid permease Chitin_synth_2 PF03142.15 CBY10284.1 - 1.7e-28 99.6 1.6 1.8e-23 83.0 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CBY10284.1 - 4.4e-11 43.1 8.1 4.4e-11 43.1 8.1 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CBY10284.1 - 3.3e-10 40.2 0.0 5.9e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CBY10284.1 - 0.044 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF1153 PF06627.11 CBY10284.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) Tmemb_cc2 PF10267.9 CBY10285.1 - 0.00016 21.0 1.4 0.00019 20.8 1.4 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Band_7 PF01145.25 CBY10286.1 - 7.8e-30 104.2 0.4 7.8e-30 104.2 0.4 2.3 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CBY10286.1 - 4.6e-21 74.6 0.2 1.1e-20 73.4 0.2 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 CBY10286.1 - 0.016 15.0 0.0 0.032 13.9 0.0 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family Pkinase PF00069.25 CBY10287.1 - 2.7e-59 200.7 0.1 5.1e-59 199.8 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10287.1 - 5.3e-38 130.8 0.0 6.7e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY10287.1 - 1.6e-09 37.1 0.0 2.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY10287.1 - 3.7e-05 23.2 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY10287.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY10287.1 - 0.0042 17.0 0.0 0.03 14.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CBY10287.1 - 0.032 13.9 0.1 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CBY10287.1 - 0.061 12.9 0.0 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CBY10287.1 - 0.072 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Dynactin PF12455.8 CBY10288.1 - 3.4e-43 147.9 0.2 3.4e-43 147.9 0.2 3.4 4 1 1 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 CBY10288.1 - 1.3e-21 76.4 0.9 2.2e-21 75.6 0.9 1.4 1 0 0 1 1 1 1 CAP-Gly domain DivIC PF04977.15 CBY10288.1 - 0.0029 17.3 2.9 0.0029 17.3 2.9 7.8 5 4 3 8 8 8 1 Septum formation initiator DUF365 PF04033.12 CBY10288.1 - 0.25 11.6 3.7 0.79 10.0 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF365) tRNA-synt_1b PF00579.25 CBY10288.1 - 3.7 6.8 9.0 2.6 7.3 3.8 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) bZIP_1 PF00170.21 CBY10289.1 - 0.00046 20.2 13.8 0.00046 20.2 13.8 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 CBY10289.1 - 0.0009 19.7 13.5 0.0009 19.7 13.5 2.0 1 1 1 2 2 2 1 bZIP Maf transcription factor RPA_interact_C PF14768.6 CBY10289.1 - 0.089 13.4 0.2 0.14 12.7 0.2 1.5 1 1 0 1 1 1 0 Replication protein A interacting C-terminal PIN_8 PF18476.1 CBY10289.1 - 0.13 12.1 9.2 0.16 11.8 9.2 1.1 1 0 0 1 1 1 0 PIN like domain OEP PF02321.18 CBY10289.1 - 0.17 11.7 8.9 0.16 11.8 7.9 1.5 1 1 0 1 1 1 0 Outer membrane efflux protein UPF0242 PF06785.11 CBY10289.1 - 0.68 10.0 10.0 0.84 9.7 10.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus VSG_B PF13206.6 CBY10289.1 - 1.4 8.1 11.8 1.6 7.9 11.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain TALPID3 PF15324.6 CBY10289.1 - 5.1 4.6 11.8 5.7 4.5 11.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target bZIP_2 PF07716.15 CBY10289.1 - 5.4 7.2 23.2 0.85 9.8 17.8 2.5 2 1 0 2 2 2 0 Basic region leucine zipper AAA_23 PF13476.6 CBY10289.1 - 8.2 6.9 15.4 10 6.6 15.4 1.1 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 CBY10289.1 - 8.9 5.5 7.4 11 5.1 7.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Beta-lactamase PF00144.24 CBY10290.1 - 2.4e-29 102.6 0.0 5e-29 101.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Ion_trans PF00520.31 CBY10291.1 - 7.1e-215 709.9 87.0 6.6e-63 212.2 7.7 4.3 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CBY10291.1 - 2.5e-11 42.9 88.0 0.00026 19.8 6.3 10.8 7 3 3 10 10 10 8 Polycystin cation channel GPHH PF16905.5 CBY10291.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Glyco_hydro_9 PF00759.19 CBY10292.1 - 8.8e-124 414.1 3.3 1e-123 413.8 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF2332 PF10094.9 CBY10292.1 - 0.052 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Sulfotransfer_2 PF03567.14 CBY10293.1 - 5.7e-12 46.1 4.5 7.1e-12 45.8 4.5 1.0 1 0 0 1 1 1 1 Sulfotransferase family Phage_1_1 PF08200.11 CBY10293.1 - 0.023 15.1 0.3 0.046 14.1 0.3 1.5 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein zf-CSL PF05207.13 CBY10293.1 - 0.082 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 CSL zinc finger Pkinase PF00069.25 CBY10294.1 - 1.2e-50 172.4 0.0 1.7e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10294.1 - 5.1e-19 68.6 0.0 7.3e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY10294.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY10294.1 - 0.0046 15.8 0.0 0.0072 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 CBY10294.1 - 0.1 12.2 0.1 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 CBY10295.1 - 6.5e-36 123.9 0.5 1.7e-34 119.3 0.5 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY10295.1 - 1e-17 64.4 0.0 1.8e-17 63.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY10295.1 - 0.0087 14.9 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PDZ PF00595.24 CBY10296.1 - 0.00029 21.1 0.1 0.00037 20.8 0.1 1.3 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY10296.1 - 0.00063 19.5 0.0 0.0008 19.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY10296.1 - 0.043 14.1 0.0 0.051 13.9 0.0 1.1 1 0 0 1 1 1 0 PDZ domain Pkinase_Tyr PF07714.17 CBY10297.1 - 2.1e-05 23.9 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY10297.1 - 0.00055 19.4 0.1 0.04 13.3 0.1 2.3 1 1 0 1 1 1 1 Protein kinase domain DUF4342 PF14242.6 CBY10297.1 - 0.081 12.9 0.4 0.21 11.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Rotavirus_VP7 PF05868.11 CBY10298.1 - 0.0059 16.0 1.1 0.65 9.3 0.2 2.5 2 0 0 2 2 2 2 Rotavirus major outer capsid protein VP7 DUF402 PF04167.13 CBY10298.1 - 0.03 14.5 0.6 14 5.9 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF402) TAFA PF12020.8 CBY10298.1 - 5.8 7.4 17.3 3.4 8.2 0.1 5.2 6 0 0 6 6 6 0 TAFA family AAA_6 PF12774.7 CBY10299.1 - 2.9e-117 391.3 0.2 7.5e-117 389.9 0.1 1.9 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 CBY10299.1 - 1.5e-61 208.3 0.0 3.1e-61 207.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CBY10299.1 - 4.1e-32 111.3 1.9 6.9e-32 110.5 0.3 2.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain DHC_N2 PF08393.13 CBY10299.1 - 1.3e-22 80.4 0.0 1.3e-22 80.4 0.0 3.5 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CBY10299.1 - 1.1e-14 54.6 0.1 5.1e-08 33.0 0.0 3.7 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY10299.1 - 5.3e-11 42.3 0.4 0.0014 18.2 0.0 3.7 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_18 PF13238.6 CBY10299.1 - 7.8e-10 39.4 5.0 0.00013 22.5 0.1 3.6 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 CBY10299.1 - 2.5e-07 31.2 4.7 0.0011 19.4 0.1 3.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CBY10299.1 - 6e-05 23.2 0.0 0.43 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CBY10299.1 - 0.0002 21.7 0.1 1.5 9.2 0.0 3.3 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 CBY10299.1 - 0.00027 21.4 0.3 0.58 10.5 0.0 3.2 3 0 0 3 3 2 1 AAA ATPase domain AAA_30 PF13604.6 CBY10299.1 - 0.00033 20.4 0.3 0.58 9.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CBY10299.1 - 0.00039 21.0 0.1 0.0016 19.0 0.1 2.0 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 CBY10299.1 - 0.00042 20.1 4.2 0.0016 18.2 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CBY10299.1 - 0.00051 20.3 1.9 0.097 12.9 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 CBY10299.1 - 0.00067 19.9 0.1 1.9 8.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CBY10299.1 - 0.0028 17.7 0.5 1 9.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 CBY10299.1 - 0.0048 16.2 0.7 0.29 10.4 0.2 2.4 2 0 0 2 2 2 1 Septin Rad17 PF03215.15 CBY10299.1 - 0.01 15.7 0.0 0.47 10.4 0.0 3.1 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CBY10299.1 - 0.013 14.9 0.5 0.041 13.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CBY10299.1 - 0.035 14.4 0.7 2.8 8.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 CBY10299.1 - 0.046 12.3 0.8 1.3 7.5 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_29 PF13555.6 CBY10299.1 - 0.053 13.3 0.3 0.15 11.8 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 CBY10299.1 - 0.079 12.7 0.2 0.33 10.7 0.1 2.1 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 CBY10299.1 - 0.081 12.7 1.4 0.76 9.5 0.1 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 CBY10299.1 - 0.1 12.3 0.3 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase APS_kinase PF01583.20 CBY10299.1 - 0.13 12.2 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 CBY10299.1 - 0.15 11.9 0.6 4.2 7.3 0.2 2.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 CBY10299.1 - 0.17 11.2 0.2 21 4.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 CBY10299.1 - 0.26 10.6 1.5 0.38 10.1 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family CbiA PF01656.23 CBY10299.1 - 0.33 11.0 3.7 7.6 6.6 1.1 3.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Roc PF08477.13 CBY10299.1 - 0.65 10.2 3.2 2.2 8.5 0.1 3.5 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase HU-CCDC81_bac_2 PF18175.1 CBY10299.1 - 4.5 7.2 5.4 3.6 7.5 0.6 3.3 4 0 0 4 4 3 0 CCDC81-like prokaryotic HU domain 2 Gelsolin PF00626.22 CBY10300.1 - 1.1e-06 28.4 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Gelsolin repeat Gelsolin PF00626.22 CBY10301.1 - 2.5e-26 91.4 0.1 9e-15 54.3 0.0 2.2 2 0 0 2 2 2 2 Gelsolin repeat Sugar_tr PF00083.24 CBY10302.1 - 6.6e-110 368.1 21.6 7.9e-110 367.8 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY10302.1 - 2.9e-21 75.8 22.4 4.6e-21 75.1 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Neur_chan_memb PF02932.16 CBY10304.1 - 2.5e-06 27.7 0.0 3.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ATPgrasp_Ter PF15632.6 CBY10304.1 - 0.057 13.2 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Neur_chan_LBD PF02931.23 CBY10305.1 - 5.2e-25 88.2 0.0 6.7e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ig PF00047.25 CBY10306.1 - 0.035 14.3 0.2 0.24 11.6 0.2 2.2 1 1 0 1 1 1 0 Immunoglobulin domain BTB_2 PF02214.22 CBY10308.1 - 4.4e-26 91.1 0.0 1.7e-25 89.2 0.0 2.1 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 CBY10308.1 - 1.9e-18 66.6 3.1 5.3e-17 61.9 0.3 2.2 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 CBY10308.1 - 6.4e-13 48.5 1.1 6.4e-13 48.5 1.1 1.9 2 0 0 2 2 2 1 Ion channel ECF_trnsprt PF12822.7 CBY10308.1 - 0.13 12.4 1.4 0.17 12.0 0.2 1.6 2 0 0 2 2 2 0 ECF transporter, substrate-specific component DUF3784 PF12650.7 CBY10308.1 - 0.15 12.2 0.2 33 4.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Kelch_6 PF13964.6 CBY10309.1 - 0.032 14.5 5.1 4.3 7.8 0.0 3.5 2 1 1 3 3 3 0 Kelch motif REPA_OB_2 PF16900.5 CBY10309.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Replication protein A OB domain ShK PF01549.24 CBY10311.1 - 0.00049 20.6 42.8 0.016 15.7 7.5 4.6 4 0 0 4 4 4 4 ShK domain-like TPR_12 PF13424.6 CBY10313.1 - 4e-60 200.1 28.8 2e-17 63.3 2.7 5.1 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 CBY10313.1 - 2.2e-53 176.8 17.0 3.6e-13 48.9 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 CBY10313.1 - 1.1e-27 94.0 14.3 2.5e-05 24.0 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 CBY10313.1 - 4.7e-20 70.5 26.9 9.4e-06 25.2 0.3 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBY10313.1 - 5.6e-15 54.2 26.3 0.0051 16.8 0.7 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBY10313.1 - 4.4e-12 45.2 21.1 0.00069 19.6 0.9 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY10313.1 - 1.8e-09 37.9 9.7 1.9e-05 25.1 0.5 4.8 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY10313.1 - 3.3e-08 34.0 14.6 0.02 15.5 0.5 5.7 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY10313.1 - 1.2e-07 31.5 4.8 1.2e-07 31.5 4.8 3.1 3 1 0 3 3 3 1 MalT-like TPR region TPR_17 PF13431.6 CBY10313.1 - 8.9e-07 28.9 7.5 0.25 11.8 0.2 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY10313.1 - 3.6e-05 23.9 5.6 0.15 12.3 0.1 3.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CBY10313.1 - 9.2e-05 23.0 23.6 1 10.3 0.1 6.7 5 1 3 8 8 5 2 Tetratricopeptide repeat PPR PF01535.20 CBY10313.1 - 0.00011 22.3 3.1 0.024 14.9 0.0 4.7 6 0 0 6 6 4 1 PPR repeat TPR_4 PF07721.14 CBY10313.1 - 0.0016 18.9 0.0 46 5.1 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.6 CBY10313.1 - 0.021 15.0 0.8 0.99 9.6 0.1 3.3 3 0 0 3 3 3 0 PPR repeat family L27 PF02828.16 CBY10313.1 - 0.039 13.7 0.5 1.9 8.3 0.0 3.1 2 1 1 3 3 3 0 L27 domain GHL5 PF14872.6 CBY10313.1 - 0.095 10.7 0.5 0.14 10.2 0.1 1.4 2 0 0 2 2 2 0 Hypothetical glycoside hydrolase 5 DUF1897 PF09005.10 CBY10313.1 - 0.1 12.1 6.2 2.9 7.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) RPN6_N PF18055.1 CBY10313.1 - 0.3 11.4 7.1 2.7 8.4 0.2 4.2 3 2 1 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain TMF_TATA_bd PF12325.8 CBY10313.1 - 0.92 9.7 10.2 0.14 12.4 2.3 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding RPN7 PF10602.9 CBY10313.1 - 1.2 8.8 10.1 0.3 10.8 1.6 3.5 2 1 2 4 4 4 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 CBY10313.1 - 2.2 9.1 16.5 1.8 9.4 0.6 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ZapB PF06005.12 CBY10313.1 - 3.6 8.1 7.0 8.1 7.0 1.9 3.0 2 0 0 2 2 2 0 Cell division protein ZapB HalX PF08663.10 CBY10314.1 - 0.017 15.4 0.2 0.017 15.4 0.2 1.6 2 0 0 2 2 2 0 HalX domain LCD1 PF09798.9 CBY10314.1 - 0.18 10.3 5.1 0.21 10.0 5.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Ig_3 PF13927.6 CBY10315.1 - 8.3e-11 42.3 0.1 1.7e-08 34.9 0.1 3.2 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CBY10315.1 - 3e-09 36.8 1.5 1.4e-06 28.2 0.0 3.4 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY10315.1 - 4.7e-08 33.3 0.1 1.4e-07 31.7 0.1 1.9 1 1 1 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 CBY10315.1 - 0.0016 18.6 0.0 0.0051 17.1 0.0 1.9 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CBY10315.1 - 0.0031 17.9 0.0 0.0097 16.3 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ig PF00047.25 CBY10315.1 - 0.021 15.0 0.3 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain C2-set_2 PF08205.12 CBY10315.1 - 0.043 13.9 0.3 0.36 10.9 0.0 2.7 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 CBY10316.1 - 1.1e-16 60.7 0.0 2.2e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY10316.1 - 6.6e-16 58.7 0.0 3.4e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CBY10316.1 - 5.2e-12 45.9 0.0 4.7e-08 33.2 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY10316.1 - 5.7e-12 45.5 0.2 5.4e-11 42.4 0.0 2.3 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 CBY10316.1 - 9.6e-10 38.5 0.0 0.00053 20.1 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CBY10316.1 - 2.5e-09 37.3 0.0 0.00015 22.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 CBY10316.1 - 0.014 15.8 0.0 0.72 10.3 0.0 2.6 3 0 0 3 3 3 0 Immunoglobulin C1-set domain TPR_1 PF00515.28 CBY10321.1 - 5.5e-14 51.3 1.3 0.00038 20.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY10321.1 - 1.9e-13 49.4 3.4 0.00042 20.2 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY10321.1 - 2.9e-10 40.5 1.3 4.7e-06 27.0 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY10321.1 - 4.8e-08 33.5 1.5 0.00011 22.8 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY10321.1 - 6.6e-08 32.8 0.6 0.018 15.8 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY10321.1 - 5.1e-07 29.4 3.1 0.39 11.0 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBY10321.1 - 8e-07 28.6 0.9 0.0018 17.9 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 CBY10321.1 - 7e-05 23.0 2.0 1.3 9.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY10321.1 - 9.2e-05 22.6 0.6 0.00018 21.7 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBY10321.1 - 0.00019 21.6 0.4 1.4 9.4 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY10321.1 - 0.00034 21.1 4.1 1.1 10.0 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY10321.1 - 0.0036 17.4 2.0 0.0089 16.1 0.9 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY10321.1 - 0.0047 16.7 1.5 14 5.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBY10321.1 - 0.0084 16.6 0.1 0.47 10.9 0.2 2.5 2 1 0 2 2 2 1 Alkyl sulfatase dimerisation BTAD PF03704.17 CBY10321.1 - 0.011 16.2 0.9 0.32 11.4 0.9 2.7 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Arnt_C PF18583.1 CBY10321.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain PPR PF01535.20 CBY10321.1 - 0.13 12.5 0.1 10 6.6 0.0 3.3 3 0 0 3 3 3 0 PPR repeat TPR_4 PF07721.14 CBY10321.1 - 0.27 12.0 1.3 14 6.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3025 PF11227.8 CBY10322.1 - 0.0067 16.3 0.1 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3025) HSBP1 PF06825.12 CBY10322.1 - 0.16 11.8 1.0 1.8 8.5 0.5 2.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 RT_RNaseH_2 PF17919.1 CBY10323.1 - 2.3e-25 88.5 0.0 4.7e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY10323.1 - 1.2e-18 67.4 0.0 2.1e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY10323.1 - 2.5e-17 63.2 0.0 4.4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY10323.1 - 2.8e-14 53.3 0.0 1.1e-13 51.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY10323.1 - 2e-06 27.8 0.0 4.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF3343 PF11823.8 CBY10323.1 - 0.025 14.0 0.3 0.075 12.5 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) zf-H2C2 PF09337.10 CBY10323.1 - 0.036 14.3 0.1 0.088 13.0 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Lectin_C PF00059.21 CBY10324.1 - 6.3e-16 59.1 1.4 5.3e-12 46.4 0.1 2.4 2 0 0 2 2 2 2 Lectin C-type domain Trefoil PF00088.18 CBY10324.1 - 0.0065 16.3 4.9 0.02 14.8 4.9 1.9 1 0 0 1 1 1 1 Trefoil (P-type) domain Kelch_2 PF07646.15 CBY10325.1 - 0.0017 18.3 0.2 0.12 12.4 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Snapin_Pallidin PF14712.6 CBY10325.1 - 0.026 14.9 0.3 0.047 14.1 0.3 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Kelch_6 PF13964.6 CBY10325.1 - 0.042 14.2 1.9 0.4 11.0 0.0 2.9 3 1 1 4 4 4 0 Kelch motif E2F_CC-MB PF16421.5 CBY10325.1 - 0.091 13.1 0.3 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain Kelch_5 PF13854.6 CBY10325.1 - 0.14 12.2 1.6 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Kelch motif GIT_CC PF16559.5 CBY10325.1 - 0.58 10.1 3.2 1 9.3 0.6 2.4 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Pox_A_type_inc PF04508.12 CBY10325.1 - 1.9 8.5 4.2 31 4.6 0.2 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DsrC PF04358.13 CBY10326.1 - 0.13 12.8 0.9 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 DsrC like protein DUF5021 PF16424.5 CBY10327.1 - 0.11 12.4 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) Period_C PF12114.8 CBY10327.1 - 9.5 5.8 8.6 36 3.9 6.3 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Thyroglobulin_1 PF00086.18 CBY10328.1 - 0.00077 19.1 4.2 0.00077 19.1 4.2 2.0 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat DUF4808 PF16066.5 CBY10328.1 - 0.17 12.5 0.1 0.42 11.2 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4808) Forkhead PF00250.18 CBY10330.1 - 5.2e-38 129.2 0.1 1.1e-37 128.2 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CBY10330.1 - 2.8e-08 34.0 0.1 6.4e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 FHA domain DUF1150 PF06620.11 CBY10330.1 - 0.035 14.2 0.1 1.4 9.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1150) HAD PF12710.7 CBY10332.1 - 6.9e-12 46.2 0.0 1e-11 45.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBY10332.1 - 6.1e-10 39.5 0.4 1.8e-09 37.9 0.4 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY10332.1 - 9.1e-07 29.4 1.0 4.1e-06 27.2 1.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY10332.1 - 1.6e-05 24.9 0.1 3.2e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF1295 PF06966.12 CBY10333.1 - 2.7e-12 46.7 1.4 3.2e-12 46.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TMEM117 PF15113.6 CBY10333.1 - 0.0084 15.1 1.5 0.0095 14.9 1.5 1.1 1 0 0 1 1 1 1 TMEM117 protein family EXS PF03124.14 CBY10335.1 - 1.4e-81 274.4 15.8 1.4e-81 274.4 15.8 1.4 2 0 0 2 2 2 1 EXS family PH PF00169.29 CBY10337.1 - 1.9e-14 54.0 0.7 3.7e-14 53.1 0.7 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CBY10337.1 - 5.2e-13 49.1 0.7 1.1e-12 48.1 0.7 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBY10337.1 - 0.0026 18.2 3.5 0.0026 18.2 3.5 2.8 2 2 1 3 3 3 1 Pleckstrin homology domain PH_6 PF15406.6 CBY10337.1 - 0.014 15.6 0.0 0.063 13.6 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF966 PF06136.13 CBY10337.1 - 0.016 15.0 1.4 0.019 14.7 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF724 PF05266.14 CBY10337.1 - 0.036 13.9 2.6 0.059 13.2 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Baculo_IE-1 PF05290.11 CBY10337.1 - 0.066 13.2 0.3 0.11 12.5 0.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) CASP_C PF08172.12 CBY10338.1 - 3.2e-53 180.7 9.4 3.2e-53 180.7 9.4 2.9 2 2 0 2 2 2 1 CASP C terminal Golgin_A5 PF09787.9 CBY10338.1 - 0.00027 20.5 8.5 0.00027 20.5 8.5 3.9 2 2 1 3 3 3 1 Golgin subfamily A member 5 bZIP_2 PF07716.15 CBY10338.1 - 0.026 14.6 3.3 0.026 14.6 3.3 5.9 5 1 1 6 6 6 0 Basic region leucine zipper DUF2205 PF10224.9 CBY10338.1 - 0.027 14.5 1.5 0.027 14.5 1.5 3.5 4 0 0 4 4 4 0 Short coiled-coil protein Csm1_N PF18504.1 CBY10338.1 - 0.038 14.3 1.0 0.038 14.3 1.0 5.1 3 1 2 5 5 5 0 Csm1 N-terminal domain DASH_Dad4 PF08650.10 CBY10338.1 - 0.16 12.0 5.6 7.8 6.6 0.8 3.0 2 0 0 2 2 2 0 DASH complex subunit Dad4 Nodulin_late PF07127.11 CBY10338.1 - 0.2 12.0 1.6 0.37 11.1 1.6 1.4 1 0 0 1 1 1 0 Late nodulin protein PDCD7 PF16021.5 CBY10338.1 - 2.1 7.4 20.8 0.18 10.9 2.1 2.4 2 1 0 2 2 2 0 Programmed cell death protein 7 DUF1652 PF07865.11 CBY10338.1 - 2.2 8.2 5.1 4.5 7.2 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) DUF4200 PF13863.6 CBY10338.1 - 4.2 7.8 28.4 0.13 12.6 1.1 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) adh_short PF00106.25 CBY10339.1 - 3.6e-25 88.6 0.0 3.2e-17 62.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY10339.1 - 2e-20 73.3 0.0 1.4e-12 47.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CBY10339.1 - 8.5e-07 28.7 0.0 4.7e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CBY10339.1 - 4.3e-05 23.5 0.0 6.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CBY10339.1 - 0.0037 16.7 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Calreticulin PF00262.18 CBY10340.1 - 4.7e-144 479.8 9.7 4.7e-144 479.8 9.7 1.7 2 0 0 2 2 2 1 Calreticulin family IBP39 PF11422.8 CBY10340.1 - 0.031 14.0 0.1 0.051 13.3 0.1 1.3 1 0 0 1 1 1 0 Initiator binding protein 39 kDa TP6A_N PF04406.14 CBY10341.1 - 1.4e-12 47.4 0.0 2.9e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 CBY10341.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Gla PF00594.20 CBY10343.1 - 2.9e-09 37.0 0.5 5.5e-09 36.1 0.5 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain F5_F8_type_C PF00754.25 CBY10343.1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain EGF PF00008.27 CBY10343.1 - 0.004 17.4 6.4 0.004 17.4 6.4 2.5 2 0 0 2 2 2 1 EGF-like domain Trypsin PF00089.26 CBY10344.1 - 5.8e-113 376.1 12.3 8e-59 199.1 0.1 2.8 3 0 0 3 3 3 2 Trypsin Trypsin_2 PF13365.6 CBY10344.1 - 1.1e-11 45.8 0.0 3.5e-07 31.2 0.0 3.0 2 1 0 2 2 2 2 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY10344.1 - 1.2e-05 25.6 0.3 0.0033 17.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Mucin PF01456.17 CBY10344.1 - 0.0034 17.4 32.4 0.0034 17.4 32.4 2.6 3 0 0 3 3 3 2 Mucin-like glycoprotein MGC-24 PF05283.11 CBY10344.1 - 0.41 11.1 20.9 0.27 11.7 9.8 2.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4969 PF16339.5 CBY10346.1 - 0.28 11.6 1.0 0.59 10.5 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) CDT1 PF08839.11 CBY10347.1 - 7.6e-45 153.3 0.1 2.9e-44 151.4 0.0 2.1 2 0 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 CBY10347.1 - 2.9e-19 69.3 1.4 2.9e-19 69.3 1.4 2.8 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain SMC_N PF02463.19 CBY10348.1 - 7.2e-57 192.3 42.6 2.7e-55 187.2 42.6 3.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBY10348.1 - 1.1e-16 61.1 0.0 3.7e-16 59.5 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CBY10348.1 - 1.5e-11 45.2 19.9 1.5e-11 45.2 19.9 7.4 2 2 2 5 5 5 1 AAA domain AAA_21 PF13304.6 CBY10348.1 - 9.8e-11 42.0 7.9 6.4e-05 22.9 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CBY10348.1 - 9.6e-08 32.1 13.8 9.6e-08 32.1 13.8 4.5 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 CBY10348.1 - 0.00053 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CBY10348.1 - 0.0015 19.0 3.9 0.0038 17.8 1.3 6.6 3 2 0 4 4 4 2 ABC transporter HAMP_N3 PF18575.1 CBY10348.1 - 0.03 13.9 0.3 0.1 12.2 0.3 2.0 1 0 0 1 1 1 0 HAMP N-terminal domain 3 TTL PF03133.15 CBY10349.1 - 5.8e-25 88.0 0.3 8.9e-25 87.4 0.3 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family TTL PF03133.15 CBY10350.1 - 9.3e-15 54.5 0.0 1.3e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family HMG_box PF00505.19 CBY10351.1 - 4e-22 78.4 3.9 7.2e-22 77.6 3.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY10351.1 - 5e-08 33.4 4.1 1.1e-07 32.3 4.1 1.5 1 0 0 1 1 1 1 HMG-box domain NINJA_B PF16136.5 CBY10351.1 - 0.021 15.2 2.4 0.056 13.8 2.4 1.7 1 0 0 1 1 1 0 Putative nuclear localisation signal Ank_4 PF13637.6 CBY10352.1 - 2.3e-27 95.0 0.3 3.9e-09 36.9 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY10352.1 - 5.6e-24 84.5 0.2 8.1e-15 55.2 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY10352.1 - 1.5e-21 75.8 0.1 5.4e-06 26.6 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CBY10352.1 - 1.4e-18 65.0 0.0 0.00047 20.4 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBY10352.1 - 7e-14 51.7 0.1 3.1e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF1843 PF08898.10 CBY10352.1 - 0.15 12.6 1.2 9.3 6.8 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) SlyX PF04102.12 CBY10352.1 - 1.4 9.6 6.4 3.6 8.3 6.4 1.7 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 CBY10352.1 - 2.5 7.9 6.4 2.9 7.7 0.1 3.2 3 0 0 3 3 3 0 Septum formation initiator Dynamin_M PF01031.20 CBY10353.1 - 3.8e-80 269.2 0.1 8.7e-80 268.0 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CBY10353.1 - 3.1e-45 154.2 0.4 6.9e-45 153.1 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CBY10353.1 - 9.1e-24 83.4 2.1 9.1e-24 83.4 2.1 1.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CBY10353.1 - 2.6e-05 24.3 0.0 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-C2H2_4 PF13894.6 CBY10354.1 - 2.7e-15 55.7 70.3 0.018 15.8 4.0 9.7 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY10354.1 - 9.6e-15 54.1 73.3 0.0014 19.0 0.3 9.7 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY10354.1 - 1e-10 41.5 9.3 3.8e-08 33.4 0.5 9.5 10 1 0 10 10 9 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBY10354.1 - 3e-07 30.1 35.4 0.0006 19.5 3.9 6.0 6 0 0 6 6 6 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CBY10354.1 - 0.00047 20.1 0.8 0.013 15.5 0.1 9.7 10 0 0 10 10 10 3 C2H2-type zinc finger zf_C2H2_10 PF18414.1 CBY10354.1 - 0.016 14.7 0.6 8.9 6.0 0.2 3.2 2 0 0 2 2 2 0 C2H2 type zinc-finger Zn_Tnp_IS1595 PF12760.7 CBY10354.1 - 0.041 13.8 29.0 0.24 11.4 0.0 5.1 5 0 0 5 5 5 0 Transposase zinc-ribbon domain Zn-C2H2_12 PF18112.1 CBY10354.1 - 1.4 9.4 0.0 1.4 9.4 0.0 5.9 8 0 0 8 8 8 0 Autophagy receptor zinc finger-C2H2 domain YacG PF03884.14 CBY10354.1 - 2.6 7.8 7.3 4.2 7.2 3.6 3.0 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG DUF2321 PF10083.9 CBY10354.1 - 3.9 7.1 15.6 0.2 11.3 0.1 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF1610 PF07754.11 CBY10354.1 - 8.5 6.4 9.4 13 5.9 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) PCNA_C PF02747.15 CBY10355.1 - 1.2e-53 180.7 0.1 5.5e-53 178.5 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 CBY10355.1 - 3e-48 162.7 3.0 4.8e-48 162.1 3.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 CBY10355.1 - 1.9e-09 37.0 0.1 3.4e-08 32.9 0.1 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CBY10355.1 - 2.5e-06 27.2 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 CBY10355.1 - 0.013 14.6 0.1 0.021 14.0 0.1 1.5 1 1 0 1 1 1 0 Hus1-like protein MKRN1_C PF15815.5 CBY10355.1 - 0.046 14.1 1.4 0.21 12.0 0.3 2.3 2 1 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal GTP_EFTU PF00009.27 CBY10356.1 - 8.3e-44 149.5 0.0 1.2e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBY10356.1 - 3.7e-23 82.0 0.1 1.1e-22 80.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain SAYSvFN PF10260.9 CBY10356.1 - 8.8e-17 60.8 0.6 1.9e-16 59.7 0.6 1.5 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) GTP_EFTU_D2 PF03144.25 CBY10356.1 - 2.1e-08 34.4 1.8 2.9e-08 34.0 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY10356.1 - 0.0029 17.7 0.0 0.0085 16.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase LPD34 PF18852.1 CBY10356.1 - 0.033 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 PAM2 PF07145.15 CBY10356.1 - 0.077 12.7 9.6 0.074 12.8 1.5 3.5 3 0 0 3 3 3 0 Ataxin-2 C-terminal region FeoB_N PF02421.18 CBY10356.1 - 0.13 11.8 0.1 1.7 8.1 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B eIF3_subunit PF08597.10 CBY10356.1 - 1.8 8.5 12.2 3.9 7.3 12.2 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FAP PF07174.11 CBY10356.1 - 2.7 7.4 12.6 4.2 6.7 12.6 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) UCH PF00443.29 CBY10357.1 - 1.7e-47 162.1 1.2 1.7e-47 162.1 1.2 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY10357.1 - 3.3e-18 66.4 6.8 3.3e-18 66.4 6.8 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CBY10357.1 - 0.76 9.2 6.6 27 4.1 6.6 3.0 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PIG-X PF08320.12 CBY10358.1 - 4.6e-15 56.1 0.4 2.1e-10 40.9 0.1 2.1 1 1 1 2 2 2 2 PIG-X / PBN1 DsbC PF11412.8 CBY10358.1 - 0.087 12.9 0.0 4.4 7.4 0.0 2.1 1 1 1 2 2 2 0 Disulphide bond corrector protein DsbC TFIID-18kDa PF02269.16 CBY10359.1 - 1.2e-27 95.7 0.1 1.5e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit MRP-S33 PF08293.11 CBY10360.1 - 2.5e-06 27.6 0.3 3.8e-06 27.0 0.3 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PHD PF00628.29 CBY10361.1 - 2.3e-07 30.6 9.2 4.5e-07 29.7 9.2 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 CBY10361.1 - 1e-05 25.3 6.4 2.2e-05 24.3 1.6 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CBY10361.1 - 0.0054 16.8 8.6 0.021 14.9 8.6 2.0 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY10361.1 - 0.02 14.4 3.9 0.048 13.2 3.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 CBY10361.1 - 0.094 12.9 6.0 0.27 11.4 6.1 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RRPl_C4 PF17026.5 CBY10361.1 - 0.11 12.6 3.8 0.27 11.3 2.4 2.1 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-RING_9 PF13901.6 CBY10361.1 - 0.18 11.7 5.7 0.32 10.9 5.7 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 CBY10361.1 - 0.51 10.7 6.4 0.71 10.2 2.8 2.3 2 0 0 2 2 2 0 C1 domain Arm PF00514.23 CBY10362.1 - 0.18 11.9 0.2 25 5.1 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Sigma70_ner PF04546.13 CBY10362.1 - 0.22 11.4 8.9 0.024 14.5 3.9 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF775 PF05603.12 CBY10364.1 - 2.6e-37 128.3 0.0 6.3e-26 91.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF775) DEAD PF00270.29 CBY10365.1 - 4e-51 173.3 0.0 8.6e-51 172.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY10365.1 - 1.6e-28 99.3 0.0 4.3e-28 97.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY10365.1 - 1.2e-05 25.4 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBY10365.1 - 0.018 14.4 0.1 0.043 13.2 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit HEM4 PF02602.15 CBY10365.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD PRAI PF00697.22 CBY10365.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF4131 PF13567.6 CBY10366.1 - 0.14 11.8 0.4 0.21 11.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Presenilin PF01080.17 CBY10366.1 - 9.4 4.9 7.4 12 4.5 7.4 1.4 1 0 0 1 1 1 0 Presenilin zf-DNL PF05180.12 CBY10367.1 - 1.5e-09 37.6 0.2 2.8e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 DNL zinc finger U5_2-snRNA_bdg PF10597.9 CBY10367.1 - 0.0088 16.1 0.0 0.044 13.9 0.0 2.0 1 1 1 2 2 2 1 U5-snRNA binding site 2 of PrP8 BTB PF00651.31 CBY10367.1 - 0.071 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain zf-AN1 PF01428.16 CBY10367.1 - 0.098 12.8 2.2 1.1 9.5 0.4 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger zf-HIT PF04438.16 CBY10367.1 - 5 7.1 9.5 11 6.0 0.5 2.2 2 0 0 2 2 2 0 HIT zinc finger UPF0121 PF03661.13 CBY10368.1 - 1.7e-61 207.7 13.6 2.1e-61 207.4 13.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF676 PF05057.14 CBY10369.1 - 1.5e-06 27.9 0.7 5.7e-06 26.0 0.7 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CBY10369.1 - 1.7e-06 28.0 0.0 4.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 CBY10369.1 - 5.1e-06 25.9 0.0 3.4e-05 23.3 0.0 2.2 3 0 0 3 3 3 1 Serine aminopeptidase, S33 LCAT PF02450.15 CBY10369.1 - 0.00041 19.6 1.2 0.00078 18.7 0.3 1.8 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.16 CBY10369.1 - 0.0012 18.7 0.1 0.015 15.1 0.1 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CBY10369.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold SASP PF00269.20 CBY10369.1 - 0.0025 17.8 0.2 0.77 9.8 0.0 2.4 2 0 0 2 2 2 1 Small, acid-soluble spore proteins, alpha/beta type DUF900 PF05990.12 CBY10369.1 - 0.0086 15.6 0.1 0.024 14.1 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 CBY10369.1 - 0.012 16.3 0.0 0.018 15.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.22 CBY10369.1 - 0.013 14.3 0.1 0.065 12.0 0.1 1.9 2 0 0 2 2 2 0 Cytochrome P450 Lipase_2 PF01674.18 CBY10369.1 - 0.016 14.7 0.1 0.11 12.0 0.1 2.2 2 0 0 2 2 2 0 Lipase (class 2) LIDHydrolase PF10230.9 CBY10369.1 - 0.046 13.3 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Palm_thioest PF02089.15 CBY10369.1 - 0.053 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CBY10369.1 - 0.061 13.0 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 CBY10369.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 CBY10369.1 - 0.11 11.9 0.0 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 CBY10369.1 - 0.12 12.1 0.1 0.88 9.3 0.1 2.3 2 1 1 3 3 3 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 CBY10369.1 - 0.14 12.0 0.1 0.71 9.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase RPN2_C PF18004.1 CBY10370.1 - 9.5e-42 142.6 7.2 1.7e-41 141.8 7.2 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CBY10370.1 - 4.3e-40 134.1 22.4 1.1e-08 35.1 0.1 8.5 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CBY10370.1 - 7.7e-20 71.1 6.2 4.2e-13 49.5 0.0 5.2 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.22 CBY10370.1 - 0.00014 21.9 1.4 6.8 7.2 0.1 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 CBY10370.1 - 0.00018 21.9 0.3 3.8 8.1 0.0 4.1 2 1 2 4 4 4 3 HEAT-like repeat ATP_bind_1 PF03029.17 CBY10371.1 - 2.1e-77 260.1 0.4 2.8e-77 259.8 0.4 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein cobW PF02492.19 CBY10371.1 - 4.8e-05 23.0 0.4 0.001 18.7 0.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CBY10371.1 - 5.1e-05 22.9 0.1 0.0017 17.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_33 PF13671.6 CBY10371.1 - 7.4e-05 22.9 0.2 0.0003 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBY10371.1 - 0.00017 21.5 0.1 0.88 9.5 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CBY10371.1 - 0.00026 21.1 0.0 0.0031 17.6 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY10371.1 - 0.00031 20.3 0.0 0.0065 16.0 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CBY10371.1 - 0.0007 20.0 0.4 0.0049 17.3 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CBY10371.1 - 0.0014 18.5 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MeaB PF03308.16 CBY10371.1 - 0.0015 17.6 0.0 0.66 8.9 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Gtr1_RagA PF04670.12 CBY10371.1 - 0.0015 18.0 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 CBY10371.1 - 0.0015 18.3 0.0 0.0039 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 CBY10371.1 - 0.0015 18.5 0.1 0.0085 16.1 0.0 2.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CBY10371.1 - 0.0017 18.7 0.0 0.0056 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBY10371.1 - 0.0023 18.5 0.9 0.008 16.7 0.0 2.3 3 0 0 3 3 1 1 AAA domain CLP1_P PF16575.5 CBY10371.1 - 0.0029 17.4 0.0 0.056 13.2 0.0 2.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 CBY10371.1 - 0.0038 16.9 0.0 0.064 12.9 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CBY10371.1 - 0.0042 17.0 0.0 0.023 14.6 0.0 2.0 1 1 0 1 1 1 1 NTPase DUF87 PF01935.17 CBY10371.1 - 0.0063 16.6 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain DMAP1 PF05499.12 CBY10371.1 - 0.014 15.3 0.9 0.025 14.5 0.9 1.3 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) AAA_5 PF07728.14 CBY10371.1 - 0.019 14.9 0.1 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arf PF00025.21 CBY10371.1 - 0.02 14.4 0.1 0.87 9.0 0.0 2.6 2 1 0 2 2 2 0 ADP-ribosylation factor family BshC PF10079.9 CBY10371.1 - 0.022 13.5 0.1 0.035 12.8 0.1 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC FtsK_SpoIIIE PF01580.18 CBY10371.1 - 0.027 13.8 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 CBY10371.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 CBY10371.1 - 0.042 13.0 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain SRPRB PF09439.10 CBY10371.1 - 0.044 13.2 0.1 0.88 9.0 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 CBY10371.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 CBY10371.1 - 0.056 13.2 0.2 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 CBY10371.1 - 0.067 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 CBY10371.1 - 0.069 12.3 1.4 1.7 7.7 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 CBY10371.1 - 0.077 13.4 0.0 0.72 10.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 CBY10371.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 CBY10371.1 - 0.11 12.1 0.7 1.6 8.4 0.0 2.5 3 0 0 3 3 2 0 Thymidylate kinase AAA_30 PF13604.6 CBY10371.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CBY10371.1 - 2 8.4 6.4 3.4 7.7 0.1 3.5 2 2 1 3 3 3 0 Dynamin family TrmB PF01978.19 CBY10372.1 - 0.034 14.0 0.2 0.04 13.8 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MCM PF00493.23 CBY10373.1 - 8.5e-94 312.8 0.0 1.3e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY10373.1 - 3.2e-36 123.9 0.2 5.9e-36 123.1 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBY10373.1 - 8.4e-29 99.8 0.0 2e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBY10373.1 - 1.9e-15 57.3 1.1 2.9e-15 56.7 0.3 1.7 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY10373.1 - 1.2e-05 24.8 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY10373.1 - 0.00015 21.7 0.0 0.00062 19.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY10373.1 - 0.0013 18.6 0.1 0.0068 16.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY10373.1 - 0.0094 15.7 0.1 0.16 11.7 0.0 2.5 3 0 0 3 3 3 1 Sigma-54 interaction domain PRELI PF04707.14 CBY10374.1 - 0.002 18.0 0.0 0.0026 17.6 0.0 1.3 1 1 0 1 1 1 1 PRELI-like family Pescadillo_N PF06732.11 CBY10376.1 - 2.1e-107 358.8 7.7 2.1e-107 358.8 7.7 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CBY10376.1 - 4.6e-07 30.2 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY10376.1 - 0.0013 19.0 0.0 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain CENP-B_dimeris PF09026.10 CBY10376.1 - 0.77 10.2 12.4 2.4 8.6 12.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TMPIT PF07851.13 CBY10376.1 - 0.89 8.7 11.0 1.6 7.9 11.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein MIB_HERC2 PF06701.13 CBY10377.1 - 5.3e-40 135.5 21.9 2.2e-26 91.8 2.5 3.9 4 0 0 4 4 4 2 Mib_herc2 SH3_15 PF18346.1 CBY10377.1 - 2e-33 114.5 8.9 1.4e-18 66.9 0.0 3.1 4 0 0 4 4 3 2 Mind bomb SH3 repeat domain Ank_2 PF12796.7 CBY10377.1 - 1.1e-28 99.6 0.1 1.1e-10 41.9 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY10377.1 - 4.2e-24 84.6 2.7 1e-07 32.4 0.0 6.1 6 2 1 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY10377.1 - 1.1e-20 73.5 3.1 4.7e-07 30.0 0.0 7.2 5 1 3 8 8 8 4 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 CBY10377.1 - 4e-20 71.4 69.0 1.5e-09 37.5 14.1 4.7 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 CBY10377.1 - 2e-16 59.6 5.0 0.00099 19.5 0.0 7.7 8 0 0 8 8 7 3 Ankyrin repeat Ank_3 PF13606.6 CBY10377.1 - 1.3e-13 49.7 3.5 0.13 12.9 0.0 8.3 8 1 0 8 8 8 4 Ankyrin repeat ZZ PF00569.17 CBY10377.1 - 3.4e-09 36.4 13.6 3.4e-09 36.4 13.6 5.1 7 0 0 7 7 5 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.6 CBY10377.1 - 0.00069 19.4 13.1 0.00069 19.4 13.1 4.9 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) DUF4314 PF14192.6 CBY10377.1 - 0.13 12.2 0.7 8.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) Prok-RING_4 PF14447.6 CBY10377.1 - 0.36 10.7 63.7 0.023 14.5 11.9 4.7 4 0 0 4 4 3 0 Prokaryotic RING finger family 4 KOW PF00467.29 CBY10377.1 - 0.49 10.4 7.0 3.6 7.7 0.5 3.7 3 0 0 3 3 3 0 KOW motif Actin PF00022.19 CBY10381.1 - 7e-100 334.5 0.0 3e-99 332.4 0.0 1.7 1 1 0 1 1 1 1 Actin DUF1917 PF08939.10 CBY10382.1 - 0.028 14.4 0.1 0.94 9.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) LPD11 PF18824.1 CBY10382.1 - 1.4 9.1 7.5 3.4 7.8 0.2 3.1 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 CTD_bind PF04818.13 CBY10382.1 - 3.1 8.7 5.1 2 9.3 0.4 2.9 3 1 0 3 3 3 0 RNA polymerase II-binding domain. DREV PF05219.12 CBY10383.1 - 4.9e-53 179.9 0.0 6e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 CBY10383.1 - 1.8e-08 34.4 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY10383.1 - 0.00067 20.4 0.1 0.0024 18.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ion_trans PF00520.31 CBY10384.1 - 5.7e-32 110.9 17.0 8.6e-32 110.3 17.0 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CBY10384.1 - 7.6e-21 74.3 0.0 1.6e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CBY10384.1 - 6.8e-14 51.6 5.6 6.8e-14 51.6 5.6 3.1 4 0 0 4 4 4 1 Ion channel Lig_chan PF00060.26 CBY10384.1 - 0.041 13.7 4.1 3.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel PKD_channel PF08016.12 CBY10384.1 - 0.13 10.9 9.9 0.032 12.9 0.9 2.2 1 1 1 2 2 2 0 Polycystin cation channel DUF2207 PF09972.9 CBY10384.1 - 0.76 8.5 4.7 0.56 8.9 0.4 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) VWD PF00094.25 CBY10385.1 - 8.1e-25 87.9 0.1 1.3e-23 84.1 0.0 2.6 3 0 0 3 3 3 1 von Willebrand factor type D domain C8 PF08742.11 CBY10385.1 - 1.8e-13 50.7 12.2 1.8e-13 50.7 12.2 2.7 2 0 0 2 2 2 1 C8 domain TIL PF01826.17 CBY10385.1 - 7.9e-05 22.8 15.5 7.9e-05 22.8 15.5 3.2 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Glyco_hydro_56 PF01630.18 CBY10386.1 - 1.8e-103 346.1 2.6 2e-103 345.9 2.6 1.0 1 0 0 1 1 1 1 Hyaluronidase ATPgrasp_ST PF14397.6 CBY10386.1 - 0.11 11.7 0.2 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp D-ser_dehydrat PF14031.6 CBY10387.1 - 2.1e-16 60.3 0.0 3.8e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CBY10387.1 - 8.4e-13 48.5 0.0 1.2e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain SIN1_PH PF16979.5 CBY10387.1 - 0.093 13.0 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Rep_fac-A_C PF08646.10 CBY10388.1 - 6.6e-42 142.7 6.9 5.4e-41 139.7 4.4 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CBY10388.1 - 1.1e-22 79.8 1.1 7e-22 77.2 0.6 2.3 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CBY10388.1 - 7.6e-12 45.0 1.6 1.9e-08 34.1 0.0 3.6 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CBY10388.1 - 0.015 15.1 1.1 0.83 9.3 0.1 3.1 3 1 0 3 3 3 0 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 CBY10388.1 - 0.029 14.6 0.3 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF223 Izumo-Ig PF16706.5 CBY10388.1 - 0.22 11.6 0.8 0.66 10.1 0.2 2.1 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ant_C PF05586.11 CBY10389.1 - 3 8.5 9.0 0.21 12.2 0.2 3.3 3 0 0 3 3 3 0 Anthrax receptor C-terminus region Pkinase PF00069.25 CBY10390.1 - 4.6e-63 213.0 0.0 9.3e-63 212.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10390.1 - 1.9e-30 106.1 0.0 3.5e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY10390.1 - 3.4e-06 26.2 7.2 1.7e-05 24.0 7.2 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY10390.1 - 0.076 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 CBY10391.1 - 4.1e-15 55.9 0.0 1.2e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain zf-CCHC_3 PF13917.6 CBY10391.1 - 3.7e-14 52.4 4.0 1.1e-13 50.8 4.0 1.9 1 0 0 1 1 1 1 Zinc knuckle Pkinase_Tyr PF07714.17 CBY10391.1 - 1.6e-12 47.3 0.0 4.2e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 CBY10391.1 - 3.2e-06 26.9 0.2 22 5.7 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.7 CBY10391.1 - 0.0021 18.1 0.0 0.023 14.8 0.0 2.3 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CBY10391.1 - 0.041 14.4 0.0 2.4 8.7 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat zf-CCHC PF00098.23 CBY10391.1 - 0.15 12.2 1.4 0.32 11.2 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Med24_N PF11277.8 CBY10391.1 - 0.44 8.5 1.9 0.67 7.9 1.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Herpes_pp85 PF04637.12 CBY10391.1 - 8.2 4.7 6.2 16 3.7 6.2 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) EF-hand_6 PF13405.6 CBY10392.1 - 0.012 15.5 0.2 0.099 12.6 0.2 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 CBY10392.1 - 0.069 12.7 0.3 0.23 11.1 0.3 1.9 1 0 0 1 1 1 0 EF hand DUF948 PF06103.11 CBY10392.1 - 0.33 11.3 2.5 7.3 6.9 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Phospholip_A2_1 PF00068.19 CBY10393.1 - 1.8e-17 63.8 10.9 1.8e-17 63.8 10.9 2.0 2 0 0 2 2 2 1 Phospholipase A2 TGF_beta_GS PF08515.12 CBY10393.1 - 0.7 9.4 0.0 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Sulfotransfer_2 PF03567.14 CBY10394.1 - 3.5e-26 92.6 0.4 5.8e-26 91.9 0.4 1.3 1 0 0 1 1 1 1 Sulfotransferase family FAD_binding_3 PF01494.19 CBY10396.1 - 2e-15 56.9 1.7 8.2e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CBY10396.1 - 0.0033 16.7 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY10396.1 - 0.011 16.0 1.4 0.025 14.8 1.4 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBY10396.1 - 0.013 14.6 1.0 0.018 14.1 1.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CBY10396.1 - 0.03 13.4 2.1 0.041 12.9 2.1 1.2 1 0 0 1 1 1 0 FAD binding domain SE PF08491.10 CBY10396.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.24 CBY10396.1 - 0.79 9.2 3.9 1.2 8.7 3.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Troponin PF00992.20 CBY10397.1 - 1.2e-24 87.2 47.9 1.2e-20 74.2 39.5 3.0 2 1 1 3 3 3 2 Troponin Homeodomain PF00046.29 CBY10398.1 - 1.8e-23 82.1 4.7 3.4e-23 81.2 4.7 1.5 1 0 0 1 1 1 1 Homeodomain DUF4706 PF15797.5 CBY10398.1 - 0.1 13.1 2.6 0.099 13.2 1.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4706) GAIN_A PF18619.1 CBY10398.1 - 0.12 12.6 0.6 0.46 10.7 0.2 2.1 1 1 1 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A GNT-I PF03071.15 CBY10400.1 - 8.3e-51 173.1 0.9 1.3e-49 169.2 0.8 2.5 1 1 0 1 1 1 1 GNT-I family MGAT2 PF05060.14 CBY10400.1 - 0.0069 15.5 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) Glycos_transf_2 PF00535.26 CBY10400.1 - 0.15 11.9 0.0 0.39 10.5 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 fn3 PF00041.21 CBY10401.1 - 0.0073 16.6 0.2 0.25 11.7 0.0 3.2 2 1 1 3 3 3 1 Fibronectin type III domain HD_6 PF18019.1 CBY10402.1 - 0.014 15.6 0.7 0.014 15.5 0.7 1.1 1 0 0 1 1 1 0 HD domain CP2 PF04516.15 CBY10403.1 - 5.6e-61 205.8 0.2 1.1e-60 204.9 0.2 1.4 1 0 0 1 1 1 1 CP2 transcription factor SelP_N PF04592.14 CBY10403.1 - 0.031 13.7 0.3 0.031 13.7 0.3 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region TraG-D_C PF12696.7 CBY10403.1 - 0.71 9.9 3.3 1.7 8.6 3.3 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG RecQ5 PF06959.11 CBY10403.1 - 0.94 9.4 10.8 2.1 8.3 10.8 1.6 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) EF-hand_13 PF17958.1 CBY10404.1 - 4.9e-26 90.4 0.0 4.6e-25 87.2 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CBY10404.1 - 5.8e-14 52.3 0.4 1.7e-13 50.8 0.4 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY10404.1 - 0.00067 19.0 0.3 0.002 17.5 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBY10404.1 - 0.0018 18.1 0.2 0.013 15.4 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY10404.1 - 0.01 15.3 0.4 0.01 15.3 0.4 2.4 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 CBY10404.1 - 0.14 12.0 0.1 0.45 10.4 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair FAD_binding_3 PF01494.19 CBY10407.1 - 3.2e-19 69.4 0.0 7.9e-19 68.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CBY10407.1 - 5.4e-06 25.8 1.0 0.011 14.9 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY10407.1 - 6.7e-05 22.2 0.1 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CBY10407.1 - 9.6e-05 22.5 0.3 0.00039 20.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 CBY10407.1 - 0.00043 19.4 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 CBY10407.1 - 0.0008 19.1 0.1 0.72 9.4 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CBY10407.1 - 0.013 14.2 1.7 0.05 12.3 1.7 1.9 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CBY10407.1 - 0.023 14.0 1.4 1.9 7.7 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBY10407.1 - 0.061 12.4 1.0 0.096 11.8 1.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CBY10407.1 - 0.18 11.8 0.2 10 6.1 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DnaJ PF00226.31 CBY10408.1 - 1.3e-14 54.1 0.2 2.4e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain SH3_9 PF14604.6 CBY10408.1 - 4.4e-09 36.1 0.0 8.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY10408.1 - 3.1e-08 33.1 0.1 5.8e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY10408.1 - 1.8e-06 27.5 0.0 2.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF3450 PF11932.8 CBY10408.1 - 0.0028 17.0 1.8 0.0049 16.2 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4201 PF13870.6 CBY10408.1 - 0.0047 16.7 1.4 0.0092 15.7 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) FliD_N PF02465.18 CBY10408.1 - 0.023 15.4 1.9 0.18 12.5 1.1 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DASH_Dam1 PF08653.10 CBY10408.1 - 0.083 12.7 0.5 0.19 11.6 0.5 1.6 1 0 0 1 1 1 0 DASH complex subunit Dam1 DASH_Dad4 PF08650.10 CBY10408.1 - 0.12 12.3 2.0 0.32 11.0 1.9 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad4 Lectin_N PF03954.14 CBY10408.1 - 0.42 10.4 2.4 0.77 9.5 2.4 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain PHD PF00628.29 CBY10409.1 - 4.6e-14 52.0 24.5 3.2e-07 30.1 10.7 2.4 2 0 0 2 2 2 2 PHD-finger Mtf2_C PF14061.6 CBY10409.1 - 5.9e-07 29.6 0.3 1.2e-06 28.6 0.3 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 PHD_4 PF16866.5 CBY10409.1 - 0.0014 18.7 18.0 0.011 15.8 3.6 2.9 2 1 0 2 2 2 2 PHD-finger Tudor_2 PF18104.1 CBY10409.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain HypA PF01155.19 CBY10409.1 - 3.7 7.6 6.4 8.6 6.4 0.5 2.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 7tm_1 PF00001.21 CBY10411.1 - 1.3e-27 96.8 5.2 1.4e-27 96.7 5.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 CBY10411.1 - 6.5e-08 32.3 1.6 6.7e-08 32.2 1.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 CBY10411.1 - 1.4e-05 24.9 3.9 2e-05 24.4 3.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CBY10411.1 - 0.00015 21.2 4.9 0.00018 21.0 4.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CBY10411.1 - 0.0022 17.8 7.4 0.19 11.4 7.4 2.0 1 1 0 1 1 1 1 Olfactory receptor Fun_ATP-synt_8 PF05933.13 CBY10411.1 - 0.043 14.0 2.6 0.043 14.0 2.6 1.9 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) FAM176 PF14851.6 CBY10411.1 - 0.093 12.4 0.2 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 FAM176 family TIR_2 PF13676.6 CBY10413.1 - 1.6e-05 25.5 0.8 9.3e-05 23.0 0.1 2.5 2 2 0 2 2 2 1 TIR domain MGS PF02142.22 CBY10413.1 - 0.01 16.0 0.2 0.046 13.9 0.2 2.1 2 0 0 2 2 2 1 MGS-like domain DUF1411 PF07199.11 CBY10415.1 - 0.02 14.5 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) TolA_bind_tri PF16331.5 CBY10415.1 - 0.034 14.2 0.2 0.076 13.1 0.2 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Spc24 PF08286.11 CBY10415.1 - 0.24 11.6 2.5 0.42 10.9 2.3 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CH PF00307.31 CBY10416.1 - 4.7e-08 33.2 0.1 5.9e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 CBY10416.1 - 0.0086 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBY10416.1 - 0.019 14.8 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 CAMSAP CH domain MFS_1 PF07690.16 CBY10417.1 - 1.9e-51 175.1 20.1 1.1e-50 172.6 16.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY10417.1 - 6.5e-12 45.0 17.4 1.3e-10 40.8 17.2 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter SHR3_chaperone PF08229.11 CBY10417.1 - 0.0048 15.9 0.1 0.0098 14.9 0.1 1.4 1 0 0 1 1 1 1 ER membrane protein SH3 MFS_2 PF13347.6 CBY10417.1 - 0.056 12.0 11.4 0.068 11.7 6.6 2.8 1 1 1 2 2 2 0 MFS/sugar transport protein DctQ PF04290.12 CBY10417.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.4 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Phospholip_A2_1 PF00068.19 CBY10418.1 - 5.5e-10 39.7 3.0 5.5e-10 39.7 3.0 1.7 2 0 0 2 2 2 1 Phospholipase A2 RasGEF PF00617.19 CBY10419.1 - 3.3e-37 128.4 0.0 5.5e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RA PF00788.23 CBY10420.1 - 2.4e-06 28.1 0.0 4.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain BTG PF07742.12 CBY10420.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 BTG family Zip PF02535.22 CBY10421.1 - 6e-10 38.9 10.1 6e-10 38.9 10.1 1.4 2 0 0 2 2 2 1 ZIP Zinc transporter PSI_PsaH PF03244.14 CBY10421.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VI MFS_1 PF07690.16 CBY10421.1 - 0.18 10.7 7.2 0.33 9.8 7.2 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily Phage_holin_4_2 PF04020.13 CBY10421.1 - 0.77 10.5 9.6 0.95 10.2 9.6 1.1 1 0 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV MerC PF03203.14 CBY10421.1 - 1.7 9.1 8.3 3.2 8.2 8.3 1.6 1 1 0 1 1 1 0 MerC mercury resistance protein Zip PF02535.22 CBY10422.1 - 0.027 13.7 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Hemerythrin PF01814.23 CBY10423.1 - 0.21 12.2 8.7 0.2 12.3 0.6 3.0 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain ERM PF00769.19 CBY10423.1 - 0.64 9.8 25.8 0.18 11.6 20.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family WXG100 PF06013.12 CBY10423.1 - 0.78 10.0 5.6 3.6 7.9 0.1 3.3 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Lectin_N PF03954.14 CBY10423.1 - 0.96 9.2 9.6 0.46 10.2 1.4 2.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 CBY10423.1 - 1.1 9.4 16.9 1.5 9.0 5.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 CBY10423.1 - 2.9 7.4 16.8 3.4 7.2 16.4 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Biopterin_H PF00351.21 CBY10425.1 - 1.2e-168 560.3 0.0 1.4e-168 560.1 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase EF-hand_7 PF13499.6 CBY10428.1 - 3.7e-12 46.5 0.9 7.1e-12 45.6 0.9 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY10428.1 - 5.9e-12 44.2 6.1 4.2e-06 25.9 1.5 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY10428.1 - 1.1e-11 43.7 2.1 1.1e-05 24.9 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY10428.1 - 1.4e-07 30.7 3.9 0.0053 16.2 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY10428.1 - 3.3e-07 30.1 5.5 4.7e-07 29.5 3.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CBY10428.1 - 0.00028 21.2 0.1 0.00051 20.3 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain GAGE PF05831.11 CBY10428.1 - 0.00088 19.8 0.5 0.0018 18.8 0.5 1.5 1 0 0 1 1 1 1 GAGE protein EF-hand_14 PF17959.1 CBY10428.1 - 0.035 14.4 0.0 0.098 13.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.7 CBY10428.1 - 0.066 13.2 0.4 0.15 12.0 0.4 1.7 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand UPF0242 PF06785.11 CBY10431.1 - 0.03 14.4 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PsbX PF06596.11 CBY10432.1 - 0.015 15.3 1.0 0.015 15.3 1.0 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) CSRNP_N PF16019.5 CBY10432.1 - 0.033 14.1 5.4 0.061 13.2 5.4 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Alpha-amyl_C2 PF07821.12 CBY10434.1 - 0.045 14.0 6.0 22 5.3 0.1 3.9 4 0 0 4 4 4 0 Alpha-amylase C-terminal beta-sheet domain LAT2 PF15703.5 CBY10434.1 - 0.095 12.6 0.2 0.28 11.1 0.2 1.8 1 0 0 1 1 1 0 Linker for activation of T-cells family member 2 DUF432 PF04254.13 CBY10435.1 - 0.0083 16.3 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF432) CN_hydrolase PF00795.22 CBY10436.1 - 7.8e-54 182.7 0.0 9.6e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPR_8 PF13181.6 CBY10438.1 - 1.1e-24 84.5 17.1 0.0028 17.7 0.2 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 CBY10438.1 - 4e-23 79.6 17.7 0.00034 20.5 0.3 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBY10438.1 - 1.5e-21 75.2 19.5 1.6e-06 27.7 0.3 7.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBY10438.1 - 3.6e-14 53.1 1.2 5.1e-07 30.2 0.0 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY10438.1 - 3.7e-14 52.2 7.5 0.091 13.6 0.0 8.6 5 2 4 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBY10438.1 - 1.3e-13 50.4 12.5 0.00013 21.6 1.1 5.5 3 1 2 5 5 5 4 TPR repeat TPR_17 PF13431.6 CBY10438.1 - 6.4e-12 45.0 18.3 6.5e-05 23.0 0.2 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY10438.1 - 8.4e-12 45.4 1.3 0.089 13.3 0.0 6.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY10438.1 - 3.5e-11 43.0 12.9 0.017 15.7 0.1 8.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY10438.1 - 4e-11 43.0 11.8 0.00083 19.6 0.9 6.4 5 1 3 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBY10438.1 - 1.4e-10 40.4 10.8 0.013 15.5 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.10 CBY10438.1 - 1.5e-05 24.2 0.2 0.012 14.6 0.1 2.4 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 CBY10438.1 - 9.4e-05 22.2 3.3 15 5.7 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY10438.1 - 0.0021 18.2 0.0 1.7 8.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBY10438.1 - 0.0043 16.3 2.6 0.0043 16.3 2.6 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CBY10438.1 - 0.0096 16.2 1.5 2.3 8.6 0.0 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat Trypsin PF00089.26 CBY10439.1 - 1.8e-49 168.5 0.4 3.1e-49 167.8 0.4 1.4 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 CBY10439.1 - 4.8e-31 107.3 0.1 8e-14 51.9 0.0 3.7 3 0 0 3 3 3 3 CUB domain Lectin_C PF00059.21 CBY10439.1 - 6.4e-12 46.2 0.1 3.4e-11 43.8 0.1 2.4 1 0 0 1 1 1 1 Lectin C-type domain CUB_2 PF02408.20 CBY10439.1 - 1.5e-07 31.2 0.8 0.044 13.5 0.0 3.6 3 1 0 3 3 3 2 CUB-like domain Trypsin_2 PF13365.6 CBY10439.1 - 1.5e-05 25.9 0.0 4.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain PTEN_C2 PF10409.9 CBY10440.1 - 0.0038 17.0 0.1 0.0043 16.8 0.1 1.1 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.27 CBY10441.1 - 3e-07 30.3 0.0 6.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBY10441.1 - 2.2e-06 27.5 0.1 1.3e-05 25.1 0.0 2.3 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBY10441.1 - 4e-05 23.7 0.0 8.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBY10441.1 - 0.012 15.7 0.3 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate LSM PF01423.22 CBY10442.1 - 3e-19 68.5 0.0 3.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain VPS11_C PF12451.8 CBY10443.1 - 0.19 12.0 0.9 4 7.8 0.0 3.2 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal Histone PF00125.24 CBY10446.1 - 1.7e-21 76.9 0.5 2.2e-21 76.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY10446.1 - 5.6e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY10446.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY10446.1 - 0.00078 19.5 0.2 0.00088 19.3 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY10446.1 - 0.039 14.2 0.8 0.11 12.8 0.8 1.7 1 1 0 1 1 1 0 CENP-W protein Histone_H2A_C PF16211.5 CBY10447.1 - 2e-20 72.2 1.3 4.1e-20 71.2 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY10447.1 - 5.8e-16 59.0 0.0 7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY10447.1 - 3.8e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2070 PF09843.9 CBY10448.1 - 0.56 8.4 13.1 0.66 8.2 13.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CENP-T_C PF15511.6 CBY10449.1 - 1.7e-08 34.6 0.1 2e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY10449.1 - 3.2e-05 24.0 0.1 4.5e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY10449.1 - 8.7e-05 22.8 0.1 0.00011 22.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY10449.1 - 0.00011 22.4 0.0 0.00017 21.8 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY10449.1 - 0.00023 21.5 0.3 0.00027 21.3 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY10449.1 - 0.0072 16.4 0.0 0.0083 16.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY10449.1 - 0.038 14.0 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY10449.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TAFII28 PF04719.14 CBY10449.1 - 0.12 12.4 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region UPF0137 PF03677.13 CBY10449.1 - 0.17 11.7 0.2 0.21 11.4 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 CBY10450.1 - 2.1e-26 92.8 1.3 2.5e-26 92.6 1.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CBY10450.1 - 0.0002 22.0 2.3 0.00023 21.7 2.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Sulfotransfer_2 PF03567.14 CBY10451.1 - 2.5e-23 83.3 0.1 3e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family zf-C2H2_4 PF13894.6 CBY10452.1 - 4.7e-06 27.0 61.0 0.18 12.7 0.1 9.2 10 0 0 10 10 10 6 C2H2-type zinc finger zf_UBZ PF18439.1 CBY10452.1 - 0.0006 19.4 11.8 1.4 8.5 0.1 4.6 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 CBY10452.1 - 0.11 13.0 0.1 0.11 13.0 0.1 8.1 9 1 0 9 9 9 0 Zinc-finger double domain zf-ribbon_3 PF13248.6 CBY10452.1 - 0.29 10.6 4.6 35 4.0 0.2 3.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF1610 PF07754.11 CBY10452.1 - 4.6 7.3 7.1 0.99 9.4 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ACC PF17848.1 CBY10452.1 - 6.4 6.9 7.7 14 5.9 0.2 3.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Cation_efflux PF01545.21 CBY10453.1 - 8.7e-40 136.6 16.6 1.1e-39 136.3 16.6 1.1 1 0 0 1 1 1 1 Cation efflux family Insulin_TMD PF17870.1 CBY10454.1 - 0.009 16.1 1.0 0.014 15.5 1.0 1.3 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment NADH5_C PF06455.11 CBY10455.1 - 0.023 14.3 2.7 0.028 14.0 2.7 1.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus DUF4131 PF13567.6 CBY10455.1 - 0.7 9.5 7.0 3.5 7.2 5.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) S_locus_glycop PF00954.20 CBY10457.1 - 0.086 13.4 0.2 0.24 11.9 0.2 1.8 1 0 0 1 1 1 0 S-locus glycoprotein domain Dimerisation PF08100.11 CBY10457.1 - 0.11 12.5 0.4 0.41 10.7 0.1 2.0 2 0 0 2 2 2 0 Dimerisation domain MH2 PF03166.14 CBY10458.1 - 1e-59 201.9 0.3 1e-59 201.9 0.3 2.5 2 1 0 2 2 2 1 MH2 domain MH1 PF03165.16 CBY10458.1 - 1.8e-23 82.7 0.4 4.7e-23 81.4 0.4 1.7 1 0 0 1 1 1 1 MH1 domain Methyltransf_23 PF13489.6 CBY10458.1 - 1.6e-17 63.8 0.1 4.6e-17 62.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY10458.1 - 2.3e-17 63.2 0.2 4.9e-17 62.1 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY10458.1 - 2.7e-17 63.2 0.0 8.4e-17 61.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY10458.1 - 6.7e-16 58.7 0.1 2.5e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CBY10458.1 - 5.1e-15 55.5 0.2 1.2e-14 54.3 0.2 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CBY10458.1 - 1.3e-13 51.5 0.0 3.7e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY10458.1 - 7.1e-07 28.8 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CBY10458.1 - 9.6e-07 28.5 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 CBY10458.1 - 2.8e-05 23.7 0.4 0.0016 17.9 0.1 2.5 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain PrmA PF06325.13 CBY10458.1 - 0.00013 21.4 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 CBY10458.1 - 0.00053 19.6 0.3 0.0012 18.5 0.3 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 CBY10458.1 - 0.0029 17.2 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CBY10458.1 - 0.0048 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Melibiase_2 PF16499.5 CBY10458.1 - 0.021 14.0 0.2 0.038 13.2 0.2 1.4 1 0 0 1 1 1 0 Alpha galactosidase A Methyltransf_18 PF12847.7 CBY10458.1 - 0.024 14.6 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 CBY10458.1 - 0.035 13.8 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.26 CBY10458.1 - 0.046 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TPMT PF05724.11 CBY10458.1 - 0.057 13.1 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 CBY10458.1 - 0.083 11.8 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Serpin PF00079.20 CBY10459.1 - 3.9e-51 174.5 0.0 4.7e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) EF-hand_1 PF00036.32 CBY10460.1 - 1.9e-06 27.0 0.0 0.41 10.3 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY10460.1 - 0.00083 19.1 0.0 2.9 8.0 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CBY10460.1 - 0.0048 17.3 0.7 2.5 8.6 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY10460.1 - 1.3 8.6 3.2 7 6.3 0.0 3.2 4 0 0 4 4 4 0 EF hand I-set PF07679.16 CBY10461.1 - 0 1788.9 6.0 1.7e-15 56.8 0.0 44.8 44 0 0 44 44 44 43 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY10461.1 - 0 1727.9 48.2 1e-14 54.8 0.0 44.6 44 0 0 44 44 44 42 Immunoglobulin domain Ig_2 PF13895.6 CBY10461.1 - 0 1122.7 0.6 8.5e-10 38.8 0.0 45.0 45 0 0 45 45 45 41 Immunoglobulin domain ig PF00047.25 CBY10461.1 - 0 1009.6 10.5 1.7e-09 37.7 0.6 44.9 44 1 0 44 44 44 42 Immunoglobulin domain C2-set_2 PF08205.12 CBY10461.1 - 7.5e-103 336.8 37.2 0.0034 17.4 0.0 38.5 40 0 0 40 40 39 22 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CBY10461.1 - 1e-92 305.6 58.8 0.0062 16.7 0.0 52.3 45 18 4 49 49 47 16 Immunoglobulin V-set domain Ig_5 PF16681.5 CBY10461.1 - 1.5e-84 278.5 0.0 0.011 16.1 0.0 37.9 39 0 0 39 39 38 10 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 CBY10461.1 - 8.6e-68 223.7 0.0 0.0096 15.5 0.0 32.3 34 0 0 34 34 33 11 Immunoglobulin domain Ig_4 PF16680.5 CBY10461.1 - 3.2e-52 174.7 9.7 0.0095 16.2 0.0 32.3 36 3 1 37 37 35 8 T-cell surface glycoprotein CD3 delta chain EGF_CA PF07645.15 CBY10461.1 - 1.4e-51 172.4 120.1 1.7e-08 34.5 9.8 11.3 9 0 0 9 9 9 8 Calcium-binding EGF domain TSP_1 PF00090.19 CBY10461.1 - 4.7e-48 161.2 102.9 7.2e-10 38.9 10.2 7.7 7 0 0 7 7 6 6 Thrombospondin type 1 domain Izumo-Ig PF16706.5 CBY10461.1 - 7e-31 106.1 12.2 0.3 11.2 0.0 26.2 33 0 0 33 33 29 3 Izumo-like Immunoglobulin domain cEGF PF12662.7 CBY10461.1 - 6.7e-26 89.9 75.3 5.5e-10 39.0 1.3 11.2 10 0 0 10 10 10 8 Complement Clr-like EGF-like G2F PF07474.12 CBY10461.1 - 2e-25 89.6 0.2 5.8e-25 88.1 0.2 1.8 1 0 0 1 1 1 1 G2F domain Receptor_2B4 PF11465.8 CBY10461.1 - 4.9e-19 68.5 6.6 0.012 15.8 0.0 14.5 14 2 1 15 15 13 2 Natural killer cell receptor 2B4 C2-set PF05790.15 CBY10461.1 - 2.2e-13 50.2 18.4 18 5.6 0.0 20.2 28 1 1 29 29 21 0 Immunoglobulin C2-set domain FXa_inhibition PF14670.6 CBY10461.1 - 5.2e-09 36.2 131.1 5.1e-08 33.1 9.4 10.8 8 1 2 10 10 9 4 Coagulation Factor Xa inhibitory site Adeno_E3_CR1 PF02440.15 CBY10461.1 - 1.7e-08 34.1 14.1 11 5.9 0.0 14.8 19 0 0 19 19 15 0 Adenovirus E3 region protein CR1 V-set_CD47 PF08204.11 CBY10461.1 - 7.7e-08 32.4 21.0 9.8 6.2 0.0 16.5 19 2 1 20 20 15 0 CD47 immunoglobulin-like domain PKD_3 PF16820.5 CBY10461.1 - 4.3e-06 26.4 6.1 1.5 8.6 0.0 8.1 9 0 0 9 9 8 2 PKD-like domain EGF PF00008.27 CBY10461.1 - 0.00012 22.3 19.5 0.00047 20.4 6.7 11.7 10 0 0 10 10 9 4 EGF-like domain DUF1533 PF07550.11 CBY10461.1 - 0.1 12.5 1.0 65 3.5 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1533) Cadherin PF00028.17 CBY10461.1 - 0.11 12.9 0.0 2 8.9 0.0 3.2 3 0 0 3 3 2 0 Cadherin domain Acyl-CoA_dh_1 PF00441.24 CBY10462.1 - 3.6e-37 127.9 7.7 1e-34 119.9 2.2 2.9 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Sulfotransfer_4 PF17784.1 CBY10462.1 - 3e-35 122.0 0.0 6.7e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase domain Acyl-CoA_dh_M PF02770.19 CBY10462.1 - 5.1e-26 90.7 0.5 1.1e-25 89.7 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY10462.1 - 2.6e-13 50.4 1.2 1.9e-11 44.4 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY10462.1 - 5.8e-10 39.8 0.1 2.2e-09 37.9 0.1 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 CBY10462.1 - 0.00066 19.4 0.2 0.0016 18.1 0.2 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Sulfotransfer_3 PF13469.6 CBY10462.1 - 0.0056 17.1 0.1 0.69 10.3 0.0 2.6 2 0 0 2 2 2 1 Sulfotransferase family EH_Signature PF15611.6 CBY10463.1 - 0.016 14.7 0.3 0.017 14.5 0.3 1.0 1 0 0 1 1 1 0 EH_Signature domain TM231 PF10149.9 CBY10464.1 - 1.9e-05 24.2 0.2 1.9e-05 24.2 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 231 Ncstrn_small PF18266.1 CBY10464.1 - 0.0032 17.5 0.0 0.0037 17.3 0.0 1.1 1 0 0 1 1 1 1 Nicastrin small lobe FixP_N PF14715.6 CBY10464.1 - 0.075 12.8 0.5 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP FRG1 PF06229.12 CBY10465.1 - 8.6e-53 178.9 0.0 8.6e-53 178.9 0.0 2.0 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 CBY10465.1 - 2.8e-05 24.3 0.0 0.0057 16.9 0.0 2.1 1 1 1 2 2 2 2 Fascin domain DUF1754 PF08555.10 CBY10465.1 - 0.00052 20.7 13.5 0.00052 20.7 13.5 1.9 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) WRNPLPNID PF15017.6 CBY10465.1 - 0.92 10.4 3.5 2.1 9.3 3.5 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box AP3D1 PF06375.11 CBY10465.1 - 6.1 7.1 15.8 0.46 10.7 10.2 1.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Prefoldin_2 PF01920.20 CBY10466.1 - 1.1e-18 67.2 5.7 1.1e-18 67.2 5.7 1.5 1 1 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.9 CBY10466.1 - 0.053 13.5 9.5 0.66 10.0 2.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 CBY10466.1 - 0.06 11.5 7.2 0.055 11.7 0.9 1.9 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 CBY10466.1 - 0.15 12.1 6.6 0.55 10.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 CBY10466.1 - 0.17 11.5 10.1 0.9 9.2 4.2 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Bcr-Abl_Oligo PF09036.10 CBY10466.1 - 0.18 11.8 3.7 0.73 9.9 0.6 2.5 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DHR10 PF18595.1 CBY10466.1 - 0.22 11.6 9.6 0.68 10.0 2.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 CBY10466.1 - 0.29 11.7 8.6 2.1 8.9 1.7 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region FliJ PF02050.16 CBY10466.1 - 0.33 11.2 7.9 4 7.7 0.6 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF16 PF01519.16 CBY10466.1 - 0.59 10.6 13.0 2.3 8.8 2.2 2.1 1 1 0 2 2 2 0 Protein of unknown function DUF16 Nas2_N PF18265.1 CBY10466.1 - 0.62 10.0 4.9 20 5.2 0.0 3.1 3 0 0 3 3 3 0 Nas2 N_terminal domain FlaC_arch PF05377.11 CBY10466.1 - 0.82 10.1 5.6 14 6.2 0.8 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 CBY10466.1 - 0.87 9.9 8.1 4.4 7.6 1.9 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TBCA PF02970.16 CBY10466.1 - 1.2 9.5 7.8 2.3 8.6 1.0 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A PEARLI-4 PF05278.12 CBY10466.1 - 1.9 8.0 10.0 1.5 8.4 3.4 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) SlyX PF04102.12 CBY10466.1 - 5.8 7.6 8.8 2.4 8.9 0.7 2.8 1 1 3 4 4 4 0 SlyX Ail_Lom PF06316.11 CBY10467.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Sushi PF00084.20 CBY10467.1 - 0.2 12.3 9.6 0.078 13.6 2.8 2.9 2 2 0 2 2 2 0 Sushi repeat (SCR repeat) PMP22_Claudin PF00822.20 CBY10468.1 - 8.9e-10 38.7 1.5 1.9e-09 37.6 1.5 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY10468.1 - 0.00065 20.0 0.1 0.00065 20.0 0.1 2.3 3 0 0 3 3 3 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 CBY10468.1 - 0.0079 15.7 0.0 0.0079 15.7 0.0 2.9 2 2 1 3 3 3 1 Clc-like Claudin_2 PF13903.6 CBY10468.1 - 0.38 10.5 6.7 2.7 7.7 6.8 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 CBY10468.1 - 0.67 9.8 4.9 0.24 11.2 1.5 1.8 1 1 1 2 2 2 0 Amastin surface glycoprotein Claudin_3 PF06653.11 CBY10468.1 - 1 9.3 15.3 2.3 8.2 6.6 3.0 3 1 0 3 3 3 0 Tight junction protein, Claudin-like EF-hand_6 PF13405.6 CBY10470.1 - 5.2e-09 35.3 0.4 1.4e-08 34.0 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY10470.1 - 2.4e-07 29.8 0.1 5.3e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY10470.1 - 3.2e-07 30.7 0.0 4.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 CBY10470.1 - 1.2e-06 28.7 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CBY10470.1 - 3.9e-06 26.1 0.3 8.4e-06 25.1 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CBY10470.1 - 5.9e-06 26.0 0.6 0.0011 18.7 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_14 PF17959.1 CBY10470.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain FGAR-AT_linker PF18072.1 CBY10470.1 - 0.042 14.4 0.0 0.062 13.9 0.0 1.5 1 1 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain Glycos_transf_2 PF00535.26 CBY10471.1 - 3.8e-06 26.8 0.1 1.4e-05 24.9 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 ABC_tran PF00005.27 CBY10475.1 - 1.7e-31 109.5 0.0 2.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Trypsin PF00089.26 CBY10475.1 - 1.9e-30 106.4 0.1 3.3e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 Trypsin ShK PF01549.24 CBY10475.1 - 6.3e-08 33.0 29.3 0.00019 21.9 8.9 2.9 2 0 0 2 2 2 2 ShK domain-like Lectin_C PF00059.21 CBY10475.1 - 8.9e-08 32.8 1.6 1.7e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 Lectin C-type domain AAA_22 PF13401.6 CBY10475.1 - 0.00032 21.0 0.1 0.0015 18.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBY10475.1 - 0.0015 18.4 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 CBY10475.1 - 0.0019 17.6 0.0 0.023 14.2 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CBY10475.1 - 0.005 15.7 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 CBY10475.1 - 0.0064 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CBY10475.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 CBY10475.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 CBY10475.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TetR_C_22 PF17928.1 CBY10475.1 - 0.14 12.5 0.0 23 5.4 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_7 PF12775.7 CBY10475.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 CBY10475.1 - 0.21 11.9 0.3 1.5 9.1 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 CBY10475.1 - 0.21 11.6 0.0 0.58 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 CBY10475.1 - 0.21 11.2 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ABC_membrane PF00664.23 CBY10476.1 - 3.4e-37 128.6 4.8 4.8e-37 128.1 4.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBY10476.1 - 7.1e-13 49.2 0.1 1.8e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CBY10476.1 - 9.7e-07 28.4 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CBY10476.1 - 0.0013 17.6 0.7 0.0024 16.7 0.1 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 CBY10476.1 - 0.0059 16.8 0.2 0.095 13.0 0.2 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit C1q PF00386.21 CBY10477.1 - 8.4e-17 61.6 1.5 1.5e-16 60.8 1.5 1.4 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 CBY10477.1 - 0.0016 18.1 6.1 0.0027 17.4 6.1 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.18 CBY10477.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Tubulin PF00091.25 CBY10478.1 - 2.8e-66 223.5 0.0 4.2e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY10478.1 - 5.5e-51 172.0 0.0 1.1e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY10478.1 - 0.0012 18.6 0.0 0.0046 16.7 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain FSA_C PF10479.9 CBY10479.1 - 0.00086 17.6 6.0 0.0011 17.2 6.0 1.2 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus Mucin PF01456.17 CBY10479.1 - 0.0096 15.9 43.9 0.0096 15.9 43.9 1.4 2 0 0 2 2 2 1 Mucin-like glycoprotein PRR18 PF15671.5 CBY10479.1 - 0.48 10.3 12.9 0.86 9.4 12.9 1.4 1 0 0 1 1 1 0 Proline-rich protein family 18 Menin PF05053.13 CBY10479.1 - 0.63 8.3 4.2 0.84 7.9 4.2 1.2 1 0 0 1 1 1 0 Menin Sporozoite_P67 PF05642.11 CBY10479.1 - 1 7.4 10.7 1.5 6.8 10.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.16 CBY10480.1 - 0.0012 17.8 25.3 0.0012 17.8 25.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily LMBR1 PF04791.16 CBY10481.1 - 0.076 11.9 6.8 0.097 11.6 6.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Guanylate_kin PF00625.21 CBY10482.1 - 4.9e-19 68.7 0.1 1.5e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Guanylate kinase LRR_4 PF12799.7 CBY10482.1 - 2e-16 59.8 36.6 3.6e-06 27.2 4.4 5.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY10482.1 - 1.9e-12 47.0 13.2 1.9e-11 43.8 3.4 2.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBY10482.1 - 5.1e-11 42.2 32.5 1.6e-05 24.6 6.3 4.2 1 1 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 CBY10482.1 - 1.1e-05 25.1 33.8 0.036 14.1 0.8 7.9 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 CBY10482.1 - 0.79 10.5 21.8 5.7 7.9 0.2 7.2 4 2 1 5 5 5 0 Leucine Rich Repeat Iso_dh PF00180.20 CBY10483.1 - 7.1e-38 130.6 0.0 8.2e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3364 PF11844.8 CBY10483.1 - 0.15 12.3 0.4 9.9 6.5 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3364) CSTF2_hinge PF14327.6 CBY10484.1 - 6.9e-25 87.3 1.6 1.8e-24 86.0 1.6 1.8 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 CBY10484.1 - 7.5e-23 80.1 0.0 1.3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CBY10484.1 - 8.9e-17 60.4 7.8 2.8e-15 55.6 4.2 2.8 2 0 0 2 2 2 2 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 CBY10484.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RRM_Rrp7 PF17799.1 CBY10484.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain BET PF17035.5 CBY10484.1 - 0.18 12.0 1.2 0.83 9.9 0.1 2.2 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation CAF1 PF04857.20 CBY10485.1 - 3.3e-29 102.1 0.2 4.3e-29 101.7 0.2 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 CBY10485.1 - 2.7e-21 75.4 0.3 8.3e-21 73.8 0.1 2.0 2 0 0 2 2 2 1 RNA binding domain R3H PF01424.22 CBY10485.1 - 0.00075 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain DUF1688 PF07958.11 CBY10485.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) MAS20 PF02064.15 CBY10485.1 - 1.2 9.3 5.5 2.2 8.4 3.7 2.1 2 0 0 2 2 2 0 MAS20 protein import receptor LSM PF01423.22 CBY10486.1 - 8.5e-20 70.2 0.0 1e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Septin PF00735.18 CBY10487.1 - 0.00012 21.5 0.2 0.00033 20.0 0.2 1.6 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.27 CBY10487.1 - 0.00021 20.9 0.0 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY10487.1 - 0.00024 21.1 0.0 0.00079 19.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBY10487.1 - 0.00061 19.9 0.0 0.33 11.0 0.0 2.8 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 CBY10487.1 - 0.0061 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.20 CBY10487.1 - 0.0079 15.4 0.1 0.26 10.4 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 CBY10487.1 - 0.0079 16.6 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 CBY10487.1 - 0.029 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.10 CBY10487.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 CBY10487.1 - 0.18 11.6 0.0 0.84 9.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY10487.1 - 0.28 11.6 1.1 1.3 9.5 1.1 2.1 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 CBY10489.1 - 6.3e-55 186.4 0.0 8e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10489.1 - 4.7e-24 85.1 0.0 8.2e-24 84.3 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CBY10489.1 - 1.3e-05 24.6 0.5 2.1e-05 24.0 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY10489.1 - 2.6e-05 24.3 0.2 0.0008 19.4 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY10489.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBY10489.1 - 0.0041 16.8 0.2 0.0063 16.1 0.2 1.3 1 0 0 1 1 1 1 RIO1 family KIF1B PF12423.8 CBY10491.1 - 0.0006 20.2 0.1 0.0022 18.4 0.1 2.1 1 0 0 1 1 1 1 Kinesin protein 1B Carn_acyltransf PF00755.20 CBY10492.1 - 4.9e-136 454.8 0.0 8.8e-136 453.9 0.0 1.3 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ion_trans_2 PF07885.16 CBY10493.1 - 3.4e-12 46.1 0.5 5.3e-12 45.5 0.5 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CBY10493.1 - 1.4e-11 44.1 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein DMT_YdcZ PF04657.13 CBY10493.1 - 0.0078 16.5 0.0 0.0089 16.3 0.0 1.1 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ Peptidase_M14 PF00246.24 CBY10495.1 - 7.6e-72 242.5 0.2 1.1e-71 242.1 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY10495.1 - 5.1e-10 39.6 0.2 1.1e-09 38.5 0.2 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide SNF PF00209.18 CBY10497.1 - 4.6e-170 566.8 37.4 5.3e-170 566.6 37.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2956 PF11169.8 CBY10498.1 - 5.2 7.3 11.4 3.5 7.9 2.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) CUT PF02376.15 CBY10499.1 - 1.1e-30 105.6 0.1 2.4e-30 104.5 0.1 1.6 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 CBY10499.1 - 1.3e-10 40.9 2.4 3.5e-10 39.6 2.4 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY10499.1 - 9.7e-05 22.2 0.1 0.00036 20.4 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain PH_TFIIH PF08567.11 CBY10499.1 - 0.013 15.9 0.2 0.1 13.0 0.0 2.5 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain Auts2 PF15336.6 CBY10499.1 - 0.035 14.2 2.9 0.077 13.1 2.9 1.5 1 1 0 1 1 1 0 Autism susceptibility gene 2 protein OrfB_IS605 PF01385.19 CBY10499.1 - 0.4 10.9 2.5 0.74 10.0 2.5 1.4 1 0 0 1 1 1 0 Probable transposase Phospholip_A2_1 PF00068.19 CBY10500.1 - 3.4e-18 66.2 10.2 5.5e-18 65.5 10.2 1.4 1 0 0 1 1 1 1 Phospholipase A2 Lectin_C PF00059.21 CBY10501.1 - 6.5e-06 26.8 0.2 1.2e-05 25.9 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain AFP_2 PF18815.1 CBY10501.1 - 0.4 11.0 1.6 1.2 9.4 1.6 1.8 1 0 0 1 1 1 0 Bacterial antifreeze protein repeat Lectin_C PF00059.21 CBY10503.1 - 2.7e-06 28.1 0.2 5.9e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 Lectin C-type domain RhoGEF PF00621.20 CBY10503.1 - 0.2 11.9 2.1 0.29 11.4 2.1 1.2 1 0 0 1 1 1 0 RhoGEF domain AFP_2 PF18815.1 CBY10503.1 - 3 8.2 5.1 0.49 10.7 0.8 1.9 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat Phospholip_A2_1 PF00068.19 CBY10504.1 - 3.2e-15 56.6 10.1 3.2e-15 56.6 10.1 2.9 2 1 1 3 3 3 2 Phospholipase A2 Meckelin PF09773.9 CBY10506.1 - 0.018 13.2 0.8 0.025 12.7 0.8 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Cadherin_C_2 PF16492.5 CBY10506.1 - 0.026 15.3 4.6 20 6.0 5.6 2.6 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal MARVEL PF01284.23 CBY10506.1 - 1.5 8.8 18.6 0.16 12.0 11.5 2.0 1 1 1 2 2 2 0 Membrane-associating domain LapA_dom PF06305.11 CBY10506.1 - 1.8 8.4 8.5 2.3 8.1 1.3 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PLAT PF01477.23 CBY10507.1 - 1.4e-09 38.6 0.0 1.5e-09 38.4 0.0 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain RC-P840_PscD PF10657.9 CBY10507.1 - 0.022 14.9 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD HSBP1 PF06825.12 CBY10508.1 - 7.7 6.5 8.3 3.1 7.7 1.6 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 CytochromB561_N PF09786.9 CBY10509.1 - 0.0011 18.1 0.1 0.0027 16.8 0.1 1.4 1 1 1 2 2 2 1 Cytochrome B561, N terminal BBS2_C PF14782.6 CBY10509.1 - 0.012 14.4 0.1 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal BORG_CEP PF14957.6 CBY10510.1 - 0.59 11.3 7.6 0.17 13.1 4.2 1.9 2 1 0 2 2 2 0 Cdc42 effector CCDC53 PF10152.9 CBY10510.1 - 6.9 7.1 7.6 0.79 10.1 0.9 2.3 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Bac_A_amyl_C PF18612.1 CBY10513.1 - 0.098 12.4 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain Kelch_4 PF13418.6 CBY10514.1 - 0.00062 19.7 4.7 0.051 13.6 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain 3A PF00803.18 CBY10514.1 - 0.0039 16.5 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 3A/RNA2 movement protein family Kelch_2 PF07646.15 CBY10514.1 - 0.0067 16.4 0.4 0.28 11.2 0.1 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 CBY10514.1 - 0.0078 15.8 0.8 0.23 11.1 0.2 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CBY10514.1 - 0.012 15.9 0.9 44 4.5 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY10514.1 - 0.056 13.8 3.8 1.3 9.4 0.2 3.3 2 1 2 4 4 4 0 Kelch motif Kelch_5 PF13854.6 CBY10514.1 - 0.33 11.0 3.9 2.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Kelch motif Trypsin PF00089.26 CBY10516.1 - 5.1e-32 111.5 0.5 1.7e-16 60.7 0.4 2.0 1 1 1 2 2 2 2 Trypsin DUF316 PF03761.15 CBY10516.1 - 0.0071 15.9 0.0 0.033 13.8 0.0 1.8 1 1 0 2 2 2 1 Chymotrypsin family Peptidase-S1 Trypsin_2 PF13365.6 CBY10516.1 - 0.055 14.4 0.4 9.7 7.1 0.3 2.2 1 1 1 2 2 2 0 Trypsin-like peptidase domain Metallothio_Pro PF02069.16 CBY10516.1 - 0.059 13.6 0.4 0.14 12.4 0.4 1.5 1 0 0 1 1 1 0 Prokaryotic metallothionein DUF1986 PF09342.11 CBY10516.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) TSP_1 PF00090.19 CBY10517.1 - 3.1e-08 33.7 15.5 1.4e-07 31.6 3.6 17.3 16 1 1 17 17 17 7 Thrombospondin type 1 domain TSP_1 PF00090.19 CBY10520.1 - 1e-06 28.9 22.2 0.00015 21.9 5.5 4.9 4 2 0 4 4 4 2 Thrombospondin type 1 domain EF-hand_1 PF00036.32 CBY10522.1 - 6.2e-07 28.5 10.4 0.0019 17.6 0.1 3.7 2 1 1 3 3 3 3 EF hand EF-hand_5 PF13202.6 CBY10522.1 - 5.9e-05 22.4 0.3 5.9e-05 22.4 0.3 3.2 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 CBY10522.1 - 8.7e-05 22.2 11.8 0.012 15.4 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 CBY10522.1 - 0.0002 21.7 10.6 0.22 12.0 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair Phage_T7_tail PF03906.14 CBY10522.1 - 0.021 14.5 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Phage T7 tail fibre protein EF-hand_8 PF13833.6 CBY10522.1 - 0.17 11.7 10.0 0.72 9.7 0.1 3.3 4 0 0 4 4 4 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY10522.1 - 4.6 7.6 7.9 9.9 6.5 2.9 2.9 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region RT_RNaseH_2 PF17919.1 CBY10523.1 - 8e-28 96.4 0.0 1.4e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY10523.1 - 8.6e-27 93.5 0.0 1.4e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 CBY10523.1 - 0.024 14.5 0.0 10 6.0 0.0 3.2 3 0 0 3 3 3 0 Reverse transcriptase thumb domain VWC PF00093.18 CBY10525.1 - 1.4e-08 34.9 49.8 1.9e-06 28.1 23.2 13.0 4 2 6 10 10 10 2 von Willebrand factor type C domain 7tm_1 PF00001.21 CBY10526.1 - 1.1e-16 60.9 17.5 9.9e-16 57.8 17.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DnaJ PF00226.31 CBY10527.1 - 2.4e-22 78.8 0.9 2.4e-22 78.8 0.9 3.0 3 0 0 3 3 3 1 DnaJ domain Hemocyanin_N PF03722.14 CBY10527.1 - 0.12 12.8 0.7 4.5 7.8 0.0 2.8 3 0 0 3 3 3 0 Hemocyanin, all-alpha domain zf-met PF12874.7 CBY10528.1 - 1.4e-09 38.0 20.8 4.4e-05 23.7 0.2 4.1 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-DBF PF07535.12 CBY10528.1 - 0.0008 19.5 12.6 0.084 13.0 0.1 3.6 3 0 0 3 3 3 2 DBF zinc finger Methyltr_RsmF_N PF17125.5 CBY10528.1 - 0.054 14.0 0.1 0.16 12.5 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF zf-C2H2_2 PF12756.7 CBY10528.1 - 0.25 11.7 12.3 9.6 6.6 2.1 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY10528.1 - 0.29 11.5 20.7 0.77 10.1 0.1 4.3 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Asp-B-Hydro_N PF05279.11 CBY10528.1 - 4.1 7.4 12.7 1.1 9.3 8.9 1.8 1 1 1 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF3449 PF11931.8 CBY10528.1 - 5 6.9 18.5 0.78 9.5 3.3 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3449) RRP36 PF06102.12 CBY10529.1 - 6.2e-30 104.3 26.8 6.2e-30 104.3 26.8 1.8 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 Pkinase_Tyr PF07714.17 CBY10531.1 - 6.2e-68 228.9 0.0 8.8e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY10531.1 - 4.7e-49 167.1 0.0 9.9e-49 166.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY10531.1 - 0.00021 20.2 0.2 0.00051 18.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase DUF3552 PF12072.8 CBY10531.1 - 0.0012 18.2 11.5 0.0019 17.6 11.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Pox_G5 PF04599.12 CBY10531.1 - 0.037 13.1 0.1 0.053 12.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein APH PF01636.23 CBY10531.1 - 0.039 13.9 0.3 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Borrelia_P83 PF05262.11 CBY10531.1 - 0.43 9.0 6.5 0.62 8.5 6.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein LisH PF08513.11 CBY10532.1 - 0.11 12.6 0.2 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 LisH PDZ PF00595.24 CBY10533.1 - 9.2e-21 74.0 1.3 2.4e-09 37.4 0.2 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY10533.1 - 5.9e-18 64.5 1.9 2.2e-12 46.6 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY10533.1 - 7.7e-10 39.0 0.2 0.0015 18.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Condensation PF00668.20 CBY10534.1 - 0.0011 17.8 1.9 0.0011 17.8 1.9 1.9 2 0 0 2 2 2 1 Condensation domain Nsp1_C PF05064.13 CBY10534.1 - 0.15 11.8 2.0 9 6.1 0.1 2.8 3 0 0 3 3 3 0 Nsp1-like C-terminal region ShK PF01549.24 CBY10535.1 - 1.1e-22 80.3 90.9 5.7e-06 26.8 3.6 7.0 7 0 0 7 7 7 5 ShK domain-like Orbi_VP3 PF01700.16 CBY10535.1 - 0.24 9.3 0.6 0.32 8.8 0.6 1.0 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein SSP160 PF06933.11 CBY10535.1 - 0.46 8.6 18.3 0.66 8.1 18.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 CBY10535.1 - 0.95 7.4 5.6 1.3 6.9 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.11 CBY10535.1 - 1.6 8.6 6.8 3 7.8 6.8 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus COE1_DBD PF16422.5 CBY10536.1 - 3.2e-131 435.8 2.2 4.7e-131 435.3 2.2 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 CBY10536.1 - 1.3e-12 47.2 0.0 2.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 CBY10536.1 - 2.3e-12 46.8 0.2 8.5e-12 45.0 0.2 2.1 1 0 0 1 1 1 1 IPT/TIG domain SET PF00856.28 CBY10539.1 - 3e-05 24.5 0.0 6.5e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 SET domain Sulfotransfer_1 PF00685.27 CBY10541.1 - 0.00066 19.2 0.6 0.0049 16.4 0.6 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY10541.1 - 0.005 17.3 0.0 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family IQ PF00612.27 CBY10542.1 - 0.0028 17.3 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif IQ PF00612.27 CBY10543.1 - 5.1e-21 72.4 0.1 1.8e-05 24.1 0.0 3.6 3 0 0 3 3 3 3 IQ calmodulin-binding motif RIIa PF02197.17 CBY10543.1 - 6e-09 35.4 0.2 1.1e-08 34.6 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit MORN PF02493.20 CBY10545.1 - 2.8e-34 115.0 59.4 3.5e-06 26.6 1.7 8.9 8 0 0 8 8 8 8 MORN repeat DUF3619 PF12279.8 CBY10545.1 - 0.51 10.7 4.2 1.4 9.2 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) DUF4398 PF14346.6 CBY10545.1 - 4.5 8.0 14.8 2.4 8.8 8.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) AMP-binding PF00501.28 CBY10546.1 - 2.9e-85 286.4 0.0 3.5e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme OMPdecase PF00215.24 CBY10546.1 - 0.025 14.2 0.4 3.3 7.2 0.0 2.6 3 0 0 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family AMP-binding_C PF13193.6 CBY10546.1 - 0.027 15.5 0.4 0.067 14.2 0.4 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RhoGEF PF00621.20 CBY10549.1 - 7.7e-37 127.3 5.7 1.2e-36 126.6 5.7 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 CBY10549.1 - 2.6e-11 42.9 1.3 5e-11 42.0 1.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY10549.1 - 3.7e-08 32.9 0.0 7.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CBY10549.1 - 8.5e-08 32.0 0.1 1.6e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain ssDNA-exonuc_C PF10141.9 CBY10549.1 - 0.032 13.9 2.5 3.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Single-strand DNA-specific exonuclease, C terminal domain PLAC8 PF04749.17 CBY10550.1 - 4.8e-11 43.5 3.4 6.6e-11 43.1 3.4 1.2 1 0 0 1 1 1 1 PLAC8 family Melibiase_2 PF16499.5 CBY10551.1 - 8.2e-129 428.8 3.7 9.6e-129 428.6 3.7 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 CBY10551.1 - 0.0056 15.7 0.3 0.016 14.2 0.1 1.7 2 0 0 2 2 2 1 Melibiase RPN7 PF10602.9 CBY10552.1 - 1.1e-51 175.0 1.8 2.1e-51 174.1 1.8 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CBY10552.1 - 9.2e-14 51.8 0.1 2.3e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_12 PF13424.6 CBY10552.1 - 0.00077 19.7 0.1 0.0024 18.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY10552.1 - 0.0011 19.0 1.2 0.014 15.5 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY10552.1 - 0.003 17.6 2.2 0.014 15.6 0.6 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY10552.1 - 0.0047 16.7 1.5 0.014 15.2 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY10552.1 - 0.011 15.7 0.4 0.37 10.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY10552.1 - 0.054 13.4 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat BAF PF02961.14 CBY10553.1 - 8.3e-39 131.9 0.5 9.3e-39 131.8 0.5 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor DNA_pol_lambd_f PF10391.9 CBY10553.1 - 0.019 14.8 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 CBY10553.1 - 0.13 12.9 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix domain Trypsin PF00089.26 CBY10554.1 - 9.8e-31 107.3 0.2 3.5e-26 92.4 0.0 2.2 2 0 0 2 2 2 2 Trypsin Tetraspanin PF00335.20 CBY10555.1 - 7.7e-26 91.2 5.7 1e-25 90.8 5.7 1.2 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 CBY10555.1 - 0.091 12.4 8.5 0.032 13.8 5.5 1.7 1 1 1 2 2 2 0 SUR7/PalI family Corona_M PF01635.18 CBY10555.1 - 0.1 11.9 0.5 0.19 11.0 0.5 1.4 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein DUF4064 PF13273.6 CBY10555.1 - 0.79 10.0 15.8 6 7.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Pilus_CpaD PF09476.10 CBY10556.1 - 0.018 14.7 0.0 0.025 14.3 0.0 1.4 1 1 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Glucos_trans_II PF14264.6 CBY10560.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII GST_C_6 PF17171.4 CBY10561.1 - 3e-16 59.0 0.4 6.9e-16 57.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CBY10561.1 - 5e-11 43.0 0.0 1.2e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 CBY10561.1 - 1.8e-09 38.2 0.0 3.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 CBY10561.1 - 3.1e-07 30.3 0.0 6.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY10561.1 - 0.00085 19.5 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY10561.1 - 0.0044 17.2 0.1 0.0096 16.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Rab15_effector PF15208.6 CBY10561.1 - 0.028 13.7 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Rab15 effector RGCC PF15151.6 CBY10561.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Response gene to complement 32 protein family RHD_DNA_bind PF00554.22 CBY10562.1 - 9e-20 71.3 0.2 1.8e-19 70.3 0.2 1.6 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 CBY10562.1 - 2.5e-19 69.2 0.0 1e-18 67.2 0.0 2.2 1 0 0 1 1 1 1 Rel homology dimerisation domain TIG PF01833.24 CBY10562.1 - 0.0017 18.4 0.2 0.022 14.9 0.0 3.0 2 1 1 3 3 3 1 IPT/TIG domain DUF1505 PF07403.11 CBY10562.1 - 2.6 8.3 6.1 0.59 10.3 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1505) SET PF00856.28 CBY10563.1 - 3e-08 34.2 0.0 5.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 SET domain PRESAN PF09687.10 CBY10563.1 - 0.02 15.5 1.1 0.26 11.9 0.1 2.3 2 0 0 2 2 2 0 Plasmodium RESA N-terminal AF0941-like PF14591.6 CBY10563.1 - 0.05 14.2 0.1 0.05 14.2 0.1 2.1 2 0 0 2 2 2 0 AF0941-like Actin PF00022.19 CBY10564.1 - 5.3e-67 226.2 0.0 8.3e-66 222.3 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBY10564.1 - 0.0031 16.4 0.0 0.48 9.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Imm43 PF15570.6 CBY10564.1 - 0.11 12.6 3.1 2.1 8.4 1.6 2.4 1 1 1 2 2 2 0 Immunity protein 43 Sulfotransfer_2 PF03567.14 CBY10565.1 - 2.4e-09 37.5 0.0 2.9e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY10565.1 - 0.0078 15.7 0.0 0.0078 15.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY10565.1 - 0.16 12.3 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family Stathmin PF00836.19 CBY10567.1 - 0.93 9.5 13.7 0.17 11.9 6.9 2.5 2 1 0 2 2 2 0 Stathmin family Met_10 PF02475.16 CBY10568.1 - 1.1e-26 93.8 0.0 1.3e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 CBY10568.1 - 2.3e-06 27.2 0.0 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CBY10568.1 - 0.00017 22.2 0.0 0.00031 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBY10568.1 - 0.0077 15.8 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 CBY10568.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CBY10568.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CBY10568.1 - 0.024 15.3 0.0 0.044 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CBY10568.1 - 0.037 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 CBY10568.1 - 0.047 13.1 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 CBY10568.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 CBY10568.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PQ-loop PF04193.14 CBY10569.1 - 3.8e-30 103.5 3.8 3.5e-17 61.9 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 CBY10569.1 - 0.0021 18.9 9.5 0.4 11.5 5.4 2.3 2 0 0 2 2 2 2 ER lumen protein retaining receptor Sulfotransfer_2 PF03567.14 CBY10570.1 - 3.5e-10 40.2 0.2 4.7e-10 39.8 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family TAF6_C PF07571.13 CBY10571.1 - 1.7e-23 82.7 0.1 3.1e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CBY10571.1 - 1e-21 76.9 0.4 2.4e-20 72.5 0.1 2.7 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBY10571.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 2.8 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 SET PF00856.28 CBY10572.1 - 2.7e-09 37.6 0.1 4.2e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 SET domain PHD PF00628.29 CBY10573.1 - 1.2e-16 60.3 23.6 1.3e-09 37.8 5.2 2.4 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 CBY10573.1 - 0.00046 19.7 0.3 0.00046 19.7 0.3 3.0 2 1 0 2 2 2 1 PHD-finger C1_1 PF00130.22 CBY10573.1 - 0.025 14.5 22.8 0.053 13.4 4.7 2.8 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 CBY10573.1 - 0.058 13.0 13.5 0.25 10.9 2.0 2.6 1 1 2 3 3 3 0 PHD/FYVE-zinc-finger like domain DUF3458 PF11940.8 CBY10573.1 - 0.078 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold CDC45 PF02724.14 CBY10573.1 - 0.27 9.5 2.5 0.41 8.9 2.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Tnp_22_trimer PF17489.2 CBY10573.1 - 0.32 11.0 4.1 1.2 9.2 4.1 2.1 1 0 0 1 1 1 0 L1 transposable element trimerization domain Zf_RING PF16744.5 CBY10573.1 - 2 8.6 25.5 2.6 8.2 5.5 3.0 1 1 1 2 2 2 0 KIAA1045 RING finger adh_short_C2 PF13561.6 CBY10574.1 - 1.2e-52 178.8 0.5 1.4e-52 178.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY10574.1 - 4.5e-48 163.3 1.4 8.8e-48 162.3 1.5 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CBY10574.1 - 3.6e-11 43.3 0.8 4.9e-11 42.9 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY10574.1 - 0.00043 19.8 0.1 0.00072 19.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBY10574.1 - 0.00068 18.8 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 CBY10574.1 - 0.0048 16.2 0.1 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PAP2_C PF14360.6 CBY10575.1 - 7.4e-23 80.9 13.9 7.4e-23 80.9 13.9 3.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CBY10575.1 - 0.0046 16.7 8.9 0.0046 16.7 8.9 2.3 1 1 0 2 2 2 1 PAP2 superfamily CrgA PF06781.12 CBY10575.1 - 0.61 10.2 0.0 0.61 10.2 0.0 2.7 3 2 0 3 3 3 0 Cell division protein CrgA Nop14 PF04147.12 CBY10577.1 - 7.7e-42 143.5 29.7 8.5e-42 143.4 29.7 1.0 1 0 0 1 1 1 1 Nop14-like family DUF45 PF01863.17 CBY10577.1 - 1.5 8.8 8.4 0.24 11.4 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 Nop14 PF04147.12 CBY10578.1 - 4.1e-36 124.6 42.2 2.1e-35 122.2 42.2 1.9 1 1 0 1 1 1 1 Nop14-like family Phage_TAC_1 PF06222.11 CBY10578.1 - 0.079 12.7 0.2 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone RXT2_N PF08595.11 CBY10578.1 - 0.09 12.8 19.7 1.5 8.8 12.0 2.7 2 1 0 2 2 2 0 RXT2-like, N-terminal GTP_EFTU PF00009.27 CBY10579.1 - 2.6e-21 76.1 0.0 4.7e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CBY10579.1 - 1.7e-06 28.2 0.1 0.00043 20.5 0.1 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CBY10579.1 - 7.3e-05 22.7 0.2 0.096 12.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU_D2 PF03144.25 CBY10579.1 - 0.0003 21.1 0.0 0.0041 17.5 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Ras PF00071.22 CBY10579.1 - 0.00049 19.7 0.1 0.014 15.0 0.1 2.4 1 1 0 1 1 1 1 Ras family FeoB_N PF02421.18 CBY10579.1 - 0.0033 17.0 0.2 0.69 9.4 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CBY10579.1 - 0.0052 16.9 0.1 0.016 15.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CBY10579.1 - 0.0053 16.6 0.0 0.077 12.8 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CBY10579.1 - 0.0087 15.8 0.1 9.1 6.0 0.0 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CBY10579.1 - 0.069 12.6 0.2 4.3 6.8 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family Hanta_nucleocap PF00846.18 CBY10579.1 - 0.086 11.3 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Ax_dynein_light PF10211.9 CBY10580.1 - 2.3e-74 249.4 9.5 2.7e-74 249.2 9.5 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain APG6_N PF17675.1 CBY10580.1 - 0.016 15.8 8.2 0.016 15.8 8.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 CBY10580.1 - 0.019 15.1 5.5 0.019 15.1 5.5 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CBY10580.1 - 0.092 12.8 3.0 0.16 12.0 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Stathmin PF00836.19 CBY10580.1 - 0.33 10.9 13.7 0.13 12.2 11.0 1.7 2 0 0 2 2 2 0 Stathmin family TMEM192 PF14802.6 CBY10580.1 - 0.41 9.7 4.2 0.56 9.3 4.2 1.2 1 0 0 1 1 1 0 TMEM192 family FlaC_arch PF05377.11 CBY10580.1 - 0.56 10.6 3.6 13 6.3 0.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 CBY10580.1 - 0.66 10.2 12.6 0.14 12.4 9.3 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TSNAXIP1_N PF15739.5 CBY10580.1 - 0.74 10.2 15.7 0.63 10.4 3.1 2.8 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus Spc24 PF08286.11 CBY10580.1 - 2.7 8.3 8.3 11 6.3 8.4 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 ZapB PF06005.12 CBY10580.1 - 2.9 8.4 15.7 28 5.2 15.7 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 CBY10580.1 - 5.2 7.7 8.6 0.46 11.1 3.8 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF5320 PF17253.2 CBY10580.1 - 5.8 8.1 7.3 51 5.0 3.1 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) MKLP1_Arf_bdg PF16540.5 CBY10583.1 - 8.7e-31 106.1 0.1 3.1e-30 104.4 0.1 1.9 1 0 0 1 1 1 1 Arf6-interacting domain of mitotic kinesin-like protein 1 ERM PF00769.19 CBY10583.1 - 0.00084 19.2 21.5 0.0013 18.6 21.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Leu_zip PF15294.6 CBY10583.1 - 0.013 15.0 13.7 0.022 14.3 13.7 1.3 1 0 0 1 1 1 0 Leucine zipper PV-1 PF06637.11 CBY10583.1 - 0.42 9.4 13.4 0.58 8.9 13.4 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) V_ATPase_I PF01496.19 CBY10583.1 - 1.9 6.3 6.8 2.5 5.9 6.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 CBY10583.1 - 3 6.5 8.6 4.3 6.1 8.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter IMUP PF15761.5 CBY10586.1 - 2.1 9.1 30.9 0.097 13.4 4.2 3.2 3 0 0 3 3 3 0 Immortalisation up-regulated protein zf-H2C2_2 PF13465.6 CBY10587.1 - 1.7e-12 47.2 3.2 3.9e-08 33.4 0.6 5.9 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY10587.1 - 7.8e-12 45.0 28.5 0.018 15.5 2.2 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY10587.1 - 2.6e-11 43.3 26.5 0.029 15.2 0.6 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2HE PF16278.5 CBY10587.1 - 0.00072 19.9 13.0 0.015 15.7 0.3 4.3 3 1 0 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger DUF3268 PF11672.8 CBY10587.1 - 0.00081 19.7 1.4 1.1 9.6 0.1 2.6 2 0 0 2 2 2 2 zinc-finger-containing domain zf-Di19 PF05605.12 CBY10587.1 - 0.0068 16.7 1.6 0.0068 16.7 1.6 3.9 2 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding PHF5 PF03660.14 CBY10587.1 - 0.014 15.5 1.5 0.22 11.8 0.1 2.5 1 1 1 2 2 2 0 PHF5-like protein DZR PF12773.7 CBY10587.1 - 0.017 15.2 6.7 0.17 12.0 0.2 3.4 3 0 0 3 3 3 0 Double zinc ribbon zf-C2H2_2 PF12756.7 CBY10587.1 - 0.05 14.0 16.1 5.9 7.3 0.3 5.0 3 1 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 CBY10587.1 - 0.068 12.9 19.4 2.2 8.1 0.7 5.0 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CBY10587.1 - 0.68 10.0 20.4 3.2 7.9 0.3 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 CBY10587.1 - 0.7 10.5 5.4 0.88 10.1 0.3 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain GATA PF00320.27 CBY10587.1 - 0.78 9.4 0.1 0.78 9.4 0.1 3.8 4 0 0 4 4 4 0 GATA zinc finger zf_C2H2_ZHX PF18387.1 CBY10587.1 - 2.6 7.8 14.8 6.4 6.5 0.4 4.4 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CBY10587.1 - 3.9 7.9 0.0 3.9 7.9 0.0 4.4 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 CBY10587.1 - 9.9 6.3 18.0 0.77 9.9 1.7 4.6 3 2 1 4 4 3 0 Sec23/Sec24 zinc finger zf-C2H2 PF00096.26 CBY10588.1 - 0.44 11.1 1.6 0.83 10.2 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Spc7_N PF15402.6 CBY10588.1 - 0.62 8.2 7.7 0.78 7.9 7.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 zf-H2C2_2 PF13465.6 CBY10589.1 - 0.037 14.5 2.7 0.037 14.5 2.7 3.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY10589.1 - 0.043 14.7 2.2 0.043 14.7 2.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger SNF PF00209.18 CBY10590.1 - 4.1e-38 131.4 27.2 1.2e-19 70.4 6.8 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family UCH PF00443.29 CBY10591.1 - 1.4e-56 191.8 0.2 1.8e-56 191.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY10591.1 - 9.6e-23 81.3 1.5 1.9e-21 77.0 1.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CBY10591.1 - 9.6e-12 45.1 10.2 9.6e-12 45.1 10.2 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-ribbon_3 PF13248.6 CBY10591.1 - 0.11 12.0 6.8 10 5.7 0.2 3.6 3 0 0 3 3 3 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.17 CBY10591.1 - 0.14 12.1 5.7 0.14 12.0 0.0 3.1 3 0 0 3 3 3 0 Domain found in IF2B/IF5 vATP-synt_AC39 PF01992.16 CBY10592.1 - 5.9e-102 341.6 0.1 6.6e-102 341.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Gal-3-0_sulfotr PF06990.11 CBY10594.1 - 5.9e-14 51.8 0.6 1.8e-13 50.2 0.6 1.6 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase Caleosin PF05042.13 CBY10595.1 - 0.022 14.7 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 Caleosin related protein DUF16 PF01519.16 CBY10595.1 - 0.085 13.4 1.3 0.16 12.5 0.4 1.7 1 1 0 2 2 2 0 Protein of unknown function DUF16 IF4E PF01652.18 CBY10596.1 - 5.2e-49 166.1 0.4 6.4e-49 165.8 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Kinesin PF00225.23 CBY10598.1 - 9e-108 360.1 0.1 2.2e-107 358.8 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY10598.1 - 1.7e-26 92.9 1.9 6.3e-26 91.1 0.1 2.6 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 CBY10598.1 - 2.2e-14 54.0 22.3 4e-11 43.4 0.6 4.9 4 2 1 5 5 5 2 Kinesin-associated FHA PF00498.26 CBY10598.1 - 6.1e-06 26.5 0.1 0.00055 20.2 0.0 3.0 2 1 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CBY10598.1 - 0.00098 19.4 0.0 0.0046 17.2 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4363 PF14276.6 CBY10598.1 - 6.9 6.8 9.2 0.45 10.6 0.8 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) DUF935 PF06074.12 CBY10599.1 - 0.1 11.3 5.6 0.11 11.3 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) V-SNARE_C PF12352.8 CBY10600.1 - 1.7e-11 44.3 1.1 2.2e-11 43.9 1.1 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBY10600.1 - 8.2e-05 22.4 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Sec20 Shufflon_N PF04917.12 CBY10600.1 - 0.018 14.5 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region DUF5089 PF17002.5 CBY10600.1 - 0.033 14.1 0.1 0.041 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) zf-RING_5 PF14634.6 CBY10601.1 - 1.6e-08 34.4 11.8 1.6e-08 34.4 11.8 2.8 3 2 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY10601.1 - 3.2e-06 27.4 12.6 3.2e-06 27.4 12.6 3.2 3 2 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY10601.1 - 0.00027 20.7 9.3 0.00027 20.7 9.3 3.1 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY10601.1 - 0.00073 19.5 5.0 0.00073 19.5 5.0 3.6 4 1 0 4 4 4 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY10601.1 - 0.0044 16.8 12.8 0.0044 16.8 12.8 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY10601.1 - 0.0046 16.8 11.6 0.0046 16.8 11.6 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY10601.1 - 0.012 15.4 11.7 0.012 15.4 11.7 3.1 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain DUF2256 PF10013.9 CBY10601.1 - 0.017 15.3 0.1 0.017 15.3 0.1 3.4 4 0 0 4 4 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FapA PF03961.13 CBY10601.1 - 0.042 12.5 1.3 0.05 12.2 1.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4398 PF14346.6 CBY10601.1 - 0.063 13.9 0.7 0.096 13.3 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) EspA PF03433.13 CBY10601.1 - 0.081 12.8 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 EspA-like secreted protein Rootletin PF15035.6 CBY10601.1 - 1 9.4 7.5 0.18 11.8 2.7 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion zf-RING_11 PF17123.5 CBY10601.1 - 1.3 8.8 8.6 1.1 9.0 1.6 3.3 3 1 0 3 3 3 0 RING-like zinc finger TSP_1 PF00090.19 CBY10602.1 - 5.7e-08 32.8 8.8 5.7e-08 32.8 8.8 3.4 2 1 1 3 3 3 2 Thrombospondin type 1 domain DUF3357 PF11837.8 CBY10603.1 - 0.014 15.9 0.1 0.017 15.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Pkinase PF00069.25 CBY10604.1 - 2.4e-59 200.8 0.2 3.1e-59 200.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10604.1 - 1.4e-35 122.9 0.1 1.8e-35 122.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY10604.1 - 1.6e-06 27.2 0.0 2.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY10604.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY10604.1 - 0.00051 19.5 0.0 0.0013 18.1 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY10604.1 - 0.049 12.6 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBY10604.1 - 0.074 13.0 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LIM PF00412.22 CBY10605.1 - 1.9e-27 95.2 23.7 3.6e-17 62.3 5.1 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CBY10605.1 - 2.4e-20 72.1 1.9 2.4e-20 72.1 1.9 1.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY10605.1 - 0.0023 17.8 0.0 0.0064 16.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Furin-like_2 PF15913.5 CBY10605.1 - 0.023 14.8 8.7 0.023 14.8 8.7 1.9 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich DUF89 PF01937.19 CBY10605.1 - 0.045 12.7 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 zf-3CxxC_2 PF17180.4 CBY10605.1 - 0.31 11.8 10.5 3 8.6 0.1 3.9 2 2 1 3 3 3 0 Zinc-binding domain Vps39_2 PF10367.9 CBY10605.1 - 1.7 9.1 8.3 20 5.7 0.6 3.3 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 BIR PF00653.21 CBY10606.1 - 4.9e-06 27.1 0.3 1.2e-05 25.8 0.0 1.8 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 CBY10606.1 - 0.02 15.0 1.1 0.96 9.5 0.0 2.5 2 0 0 2 2 2 0 C3HC zinc finger-like GlutR_dimer PF00745.20 CBY10606.1 - 0.075 13.5 0.7 0.075 13.5 0.7 2.1 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain AAA_23 PF13476.6 CBY10607.1 - 1.4e-19 71.4 6.4 1.4e-19 71.4 6.4 5.3 2 2 2 4 4 4 1 AAA domain SMC_N PF02463.19 CBY10607.1 - 6.5e-18 65.0 9.6 2e-17 63.3 9.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CBY10607.1 - 2.1e-08 34.3 15.5 2.1e-08 34.3 15.5 4.2 1 1 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CBY10607.1 - 0.00039 20.1 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MreC PF04085.14 CBY10607.1 - 0.0085 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 rod shape-determining protein MreC AAA_21 PF13304.6 CBY10607.1 - 0.02 14.7 8.9 0.062 13.1 4.0 3.7 3 2 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2661 PF10860.8 CBY10607.1 - 0.078 13.1 0.6 0.41 10.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2661) Tox-HDC PF15656.6 CBY10607.1 - 2.4 8.4 5.4 13 6.0 0.1 3.7 3 0 0 3 3 3 0 Toxin with a H, D/N and C signature VHP PF02209.19 CBY10608.1 - 0.024 14.7 2.3 3.6 7.8 0.0 3.3 3 0 0 3 3 3 0 Villin headpiece domain NuiA PF07924.11 CBY10608.1 - 0.025 15.0 0.1 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Com_YlbF PF06133.11 CBY10608.1 - 0.59 10.8 7.6 1.6 9.4 3.0 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DAG_kinase_N PF14513.6 CBY10610.1 - 0.44 10.7 0.0 0.44 10.7 0.0 3.3 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus TRH PF05438.12 CBY10610.1 - 1.3 8.8 9.9 0.55 9.9 6.8 1.9 2 0 0 2 2 2 0 Thyrotropin-releasing hormone (TRH) IFP_35_N PF07334.13 CBY10615.1 - 0.046 13.8 0.1 0.093 12.8 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AbiJ_NTD4 PF18863.1 CBY10616.1 - 0.039 14.4 1.4 0.086 13.3 1.4 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 Pro_dh-DNA_bdg PF14850.6 CBY10618.1 - 0.024 15.2 0.7 0.17 12.4 0.0 2.5 2 0 0 2 2 2 0 DNA-binding domain of Proline dehydrogenase Pkinase PF00069.25 CBY10619.1 - 2.1e-40 138.8 0.0 3e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10619.1 - 4.7e-18 65.4 0.0 7e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_binding_10 PF13460.6 CBY10620.1 - 5e-06 26.5 0.0 9.8e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CBY10620.1 - 0.00058 20.3 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain rve PF00665.26 CBY10621.1 - 3e-12 46.8 0.0 9.5e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Zeta_toxin PF06414.12 CBY10621.1 - 0.0021 17.4 0.0 0.008 15.5 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 CBY10621.1 - 0.018 15.0 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CBY10621.1 - 0.067 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBY10621.1 - 0.094 13.0 0.0 0.6 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CBY10621.1 - 7.7 6.5 10.1 4.8 7.2 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain DUF3850 PF12961.7 CBY10622.1 - 0.0068 16.4 0.0 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3850) DUF4120 PF13496.6 CBY10623.1 - 0.077 13.4 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) ABA_GPCR PF12430.8 CBY10624.1 - 2.7e-07 30.5 0.1 2.8e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor zf-CCHC_6 PF15288.6 CBY10625.1 - 0.036 13.9 2.7 0.071 13.0 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DNA_gyraseB PF00204.25 CBY10625.1 - 0.061 12.8 0.2 0.67 9.4 0.1 2.4 2 1 0 2 2 2 0 DNA gyrase B zf-CCHC_3 PF13917.6 CBY10625.1 - 0.067 13.2 3.9 0.17 11.9 3.9 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 CBY10625.1 - 0.53 10.1 3.5 1.1 9.0 3.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_3 PF07859.13 CBY10628.1 - 3.5e-39 134.9 0.0 6.2e-28 98.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 CBY10628.1 - 6.7e-07 28.5 0.1 1.9e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CBY10628.1 - 0.03 14.9 0.0 0.041 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 CBY10628.1 - 0.079 11.5 0.2 0.19 10.2 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II SBP_bac_5 PF00496.22 CBY10628.1 - 0.087 11.8 0.2 0.17 10.8 0.1 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Qn_am_d_aIII PF09099.10 CBY10628.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Say1_Mug180 PF10340.9 CBY10628.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase PALP PF00291.25 CBY10629.1 - 2e-47 162.0 0.0 2.4e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SnoaL_2 PF12680.7 CBY10629.1 - 0.21 12.3 0.0 0.36 11.5 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain PALP PF00291.25 CBY10630.1 - 1.9e-11 43.9 0.0 2.1e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_2 PF12796.7 CBY10631.1 - 1.1e-31 109.2 1.2 1.6e-09 38.2 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 CBY10631.1 - 1.9e-23 81.8 0.8 0.0011 19.3 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 CBY10631.1 - 1.1e-22 80.1 0.1 0.001 19.6 0.0 6.9 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY10631.1 - 6.7e-22 77.3 0.0 1.9e-05 24.8 0.0 5.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY10631.1 - 1.7e-15 55.5 0.0 0.053 14.1 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat FBA_1 PF07734.13 CBY10631.1 - 0.14 12.0 0.7 0.67 9.8 0.1 2.1 2 0 0 2 2 2 0 F-box associated FKBP_C PF00254.28 CBY10632.1 - 5.9e-33 113.1 0.0 6.7e-33 112.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RPE65 PF03055.15 CBY10633.1 - 4.5e-59 200.9 0.0 5.7e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Roc PF08477.13 CBY10634.1 - 0.00083 19.6 0.1 0.001 19.2 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CBY10634.1 - 0.0051 16.7 0.0 0.0051 16.7 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase Ras PF00071.22 CBY10634.1 - 0.0087 15.7 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Ras family AAA_24 PF13479.6 CBY10634.1 - 0.019 14.7 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY10634.1 - 0.05 13.1 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CBY10634.1 - 0.095 13.1 0.0 0.095 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 CBY10635.1 - 5.6e-48 162.6 0.7 6.2e-48 162.5 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY10635.1 - 1.4e-25 89.8 0.2 2.3e-25 89.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY10635.1 - 5.8e-09 35.6 0.4 6.9e-09 35.4 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY10635.1 - 0.00051 19.6 0.3 0.0011 18.5 0.3 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY10635.1 - 0.035 13.5 0.3 0.043 13.2 0.3 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NFACT-R_1 PF05670.13 CBY10637.1 - 0.072 13.7 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 NFACT protein RNA binding domain DUF3552 PF12072.8 CBY10638.1 - 0.59 9.5 33.2 0.2 11.0 12.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) SurA_N_3 PF13624.6 CBY10638.1 - 1.4 8.7 12.1 0.22 11.3 8.2 1.7 2 0 0 2 2 2 0 SurA N-terminal domain E2F_CC-MB PF16421.5 CBY10638.1 - 2.8 8.4 9.5 0.69 10.3 0.6 2.8 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain Zona_pellucida PF00100.23 CBY10639.1 - 3.8e-09 36.7 0.0 5.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF4989 PF16379.5 CBY10639.1 - 0.0023 17.3 0.7 0.0037 16.6 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4989) EF-hand_1 PF00036.32 CBY10641.1 - 0.017 14.7 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 CBY10641.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 EF hand Zona_pellucida PF00100.23 CBY10642.1 - 1.4e-10 41.5 0.0 1.8e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Cnd1 PF12717.7 CBY10644.1 - 1.3e-09 38.3 0.9 5.8e-09 36.2 0.1 2.0 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.7 CBY10644.1 - 0.095 12.6 0.4 0.23 11.4 0.4 1.7 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus DUF4500 PF14937.6 CBY10646.1 - 0.12 12.4 0.1 4.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4500) Zona_pellucida PF00100.23 CBY10647.1 - 6.6e-11 42.5 0.0 9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Med17 PF10156.9 CBY10650.1 - 0.55 8.9 3.0 0.84 8.3 3.0 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex RAMP4 PF06624.12 CBY10651.1 - 3.5e-23 81.4 0.1 3.8e-23 81.3 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Methyltransf_31 PF13847.6 CBY10652.1 - 2.3e-29 102.1 0.0 4.2e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY10652.1 - 1.5e-18 67.3 0.1 2.8e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY10652.1 - 3.1e-18 66.2 0.1 6.2e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY10652.1 - 3.2e-15 56.1 0.0 5.1e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CBY10652.1 - 3.7e-12 46.9 0.1 8.8e-12 45.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY10652.1 - 1.1e-11 44.8 0.0 2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CBY10652.1 - 3.2e-06 27.0 0.1 8e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 CBY10652.1 - 0.0001 22.3 0.2 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 Hypothetical methyltransferase PrmA PF06325.13 CBY10652.1 - 0.00085 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CBY10652.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 CBY10652.1 - 0.019 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 CBY10652.1 - 0.026 14.1 0.1 0.092 12.3 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.6 CBY10652.1 - 0.026 15.5 0.0 0.043 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 CBY10652.1 - 0.042 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.17 CBY10652.1 - 0.097 12.1 0.0 6.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase Fibrillarin PF01269.17 CBY10652.1 - 0.11 11.6 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin Ins145_P3_rec PF08709.11 CBY10653.1 - 7.1e-85 283.5 0.0 6.4e-84 280.4 0.0 2.3 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 CBY10653.1 - 1.4e-59 201.0 28.5 2.2e-50 170.9 8.0 3.8 3 0 0 3 3 3 2 RIH domain MIR PF02815.19 CBY10653.1 - 9.8e-52 175.5 1.0 2.1e-47 161.4 0.0 3.5 3 0 0 3 3 3 2 MIR domain RIH_assoc PF08454.11 CBY10653.1 - 8.8e-32 109.0 9.1 1e-31 108.7 2.5 3.8 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ion_trans PF00520.31 CBY10653.1 - 3e-11 43.0 10.7 1e-10 41.3 10.6 1.9 1 1 0 1 1 1 1 Ion transport protein Tn7_Tnp_TnsA_C PF08721.11 CBY10653.1 - 0.01 16.5 1.8 8.3 7.1 0.1 4.2 2 1 0 2 2 2 0 TnsA endonuclease C terminal Kelch_1 PF01344.25 CBY10654.1 - 0.0011 18.5 0.2 0.1 12.2 0.0 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY10654.1 - 0.003 17.8 0.4 2 8.8 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY10654.1 - 0.069 13.2 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Phospholip_A2_1 PF00068.19 CBY10655.1 - 3.7e-07 30.6 0.7 1.1e-06 29.1 0.7 1.7 1 0 0 1 1 1 1 Phospholipase A2 Big_7 PF17957.1 CBY10655.1 - 0.019 15.7 0.0 0.042 14.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig domain zf-C2H2 PF00096.26 CBY10657.1 - 2.7e-07 30.7 7.6 0.0029 18.0 1.4 2.6 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY10657.1 - 3.2e-06 27.3 3.1 7.3e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY10657.1 - 9.2e-06 25.8 0.3 0.056 13.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CBY10657.1 - 2.3e-05 25.1 0.1 0.094 13.4 0.0 2.3 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 CBY10657.1 - 4.5e-05 23.9 4.2 0.16 12.8 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY10657.1 - 0.00055 19.6 3.3 0.031 14.0 0.1 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CBY10657.1 - 0.011 16.1 0.1 2.3 8.6 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CBY10657.1 - 0.02 15.2 2.7 1.8 8.9 0.1 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon But2 PF09792.9 CBY10657.1 - 0.044 14.2 0.2 0.066 13.6 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain Actin_micro PF17003.5 CBY10657.1 - 0.056 12.6 0.1 9.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Putative actin-like family Sulfotransfer_2 PF03567.14 CBY10658.1 - 4.3e-19 69.4 0.2 4.3e-19 69.4 0.2 1.6 2 0 0 2 2 2 1 Sulfotransferase family PLAC8 PF04749.17 CBY10659.1 - 5e-18 65.9 9.1 7.5e-18 65.4 9.1 1.2 1 0 0 1 1 1 1 PLAC8 family Cadherin PF00028.17 CBY10660.1 - 7.9e-63 208.9 13.7 6e-15 55.5 0.2 6.7 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CBY10660.1 - 3.3e-22 78.1 2.6 3.3e-17 62.1 0.0 5.0 5 0 0 5 5 5 3 Cadherin-like TMEM154 PF15102.6 CBY10660.1 - 0.026 14.5 0.1 0.074 13.0 0.1 1.9 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 CBY10660.1 - 0.29 10.9 3.8 0.6 9.9 3.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Adeno_PV PF03910.13 CBY10661.1 - 0.19 10.4 1.6 0.18 10.5 1.6 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV Trypsin PF00089.26 CBY10663.1 - 5.2e-119 395.9 13.0 4.2e-70 236.0 0.1 4.5 3 1 1 4 4 4 4 Trypsin CUB PF00431.20 CBY10663.1 - 1.2e-20 73.9 0.1 7e-11 42.4 0.0 2.7 2 0 0 2 2 2 2 CUB domain Trypsin_2 PF13365.6 CBY10663.1 - 1.1e-10 42.6 0.9 0.00021 22.2 0.0 4.8 4 0 0 4 4 4 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY10663.1 - 1.4e-10 41.5 1.8 3.7e-06 27.3 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1986) DUF3439 PF11921.8 CBY10663.1 - 0.008 16.1 4.9 0.026 14.5 4.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CBY10663.1 - 0.0081 14.2 5.1 0.012 13.6 5.1 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 CBY10663.1 - 0.0089 16.0 11.4 0.029 14.4 11.4 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein Peptidase_S6 PF02395.16 CBY10663.1 - 0.014 13.5 0.4 1.2 7.1 0.2 2.1 2 0 0 2 2 2 0 Immunoglobulin A1 protease Tir_receptor_C PF07489.11 CBY10663.1 - 0.53 10.2 3.4 0.97 9.4 3.4 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SSP160 PF06933.11 CBY10663.1 - 6.5 4.8 13.2 14 3.8 13.2 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Homeodomain PF00046.29 CBY10664.1 - 1.2e-22 79.5 10.0 1.9e-22 78.8 10.0 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY10664.1 - 0.013 15.3 1.0 0.032 14.1 1.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.6 CBY10664.1 - 0.093 12.6 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Homeodomain-like domain G-gamma PF00631.22 CBY10666.1 - 1.1e-06 28.5 0.0 1.3e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain CAP PF00188.26 CBY10667.1 - 1.1e-11 45.6 3.5 2.3e-11 44.6 3.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CRF-BP PF05428.11 CBY10667.1 - 0.078 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Sushi PF00084.20 CBY10667.1 - 3.3 8.4 8.8 7.4 7.3 3.1 3.0 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Fungal_TACC PF12709.7 CBY10668.1 - 0.063 13.7 1.4 0.16 12.4 0.8 2.0 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Erf4 PF10256.9 CBY10668.1 - 0.067 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF4446 PF14584.6 CBY10668.1 - 0.098 12.6 0.3 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DivIC PF04977.15 CBY10668.1 - 0.62 9.9 2.5 24 4.8 1.0 2.4 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 CBY10668.1 - 1.5 9.5 4.6 10 6.9 0.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA SecY PF00344.20 CBY10669.1 - 2.2e-24 86.3 0.0 2.4e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 SecY translocase Trypsin PF00089.26 CBY10670.1 - 8.5e-34 117.3 1.1 1.3e-33 116.7 1.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY10670.1 - 1.2e-06 29.5 0.0 2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypan_PARP PF05887.11 CBY10672.1 - 7.4e-09 35.7 9.8 9.3e-09 35.4 9.8 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4064 PF13273.6 CBY10672.1 - 0.0025 18.1 0.0 0.02 15.2 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4064) MGC-24 PF05283.11 CBY10672.1 - 0.0051 17.3 0.0 0.0056 17.1 0.0 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4366 PF14283.6 CBY10672.1 - 0.039 14.0 1.8 0.073 13.1 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) MnhB PF04039.13 CBY10672.1 - 0.065 13.6 1.7 0.08 13.3 0.9 1.5 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF202 PF02656.15 CBY10672.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF674 PF05056.12 CBY10673.1 - 0.17 10.7 4.2 0.27 10.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF674) Connexin PF00029.19 CBY10674.1 - 7.5e-38 130.6 1.4 1e-37 130.2 1.4 1.1 1 0 0 1 1 1 1 Connexin Peptidase_M56 PF05569.11 CBY10674.1 - 0.0027 17.0 0.5 0.046 12.9 0.2 2.2 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF1461 PF07314.11 CBY10674.1 - 0.0062 16.5 3.3 0.0091 15.9 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1461) DUF5092 PF17010.5 CBY10676.1 - 0.019 14.9 3.7 1.1 9.2 0.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF5092) Gly_rich PF12810.7 CBY10677.1 - 2.3e-07 31.0 59.8 4.5e-05 23.5 59.8 2.7 1 1 0 1 1 1 1 Glycine rich protein La PF05383.17 CBY10679.1 - 1.2e-15 57.3 0.6 2.5e-15 56.2 0.6 1.6 1 0 0 1 1 1 1 La domain Trypsin PF00089.26 CBY10681.1 - 1.8e-51 175.1 0.1 2e-51 174.9 0.1 1.0 1 0 0 1 1 1 1 Trypsin O-FucT PF10250.9 CBY10682.1 - 0.0013 18.5 0.0 0.0039 16.9 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RHH_4 PF13467.6 CBY10683.1 - 0.03 14.2 0.0 0.97 9.4 0.1 3.0 3 0 0 3 3 3 0 Ribbon-helix-helix domain DUF3584 PF12128.8 CBY10683.1 - 0.048 11.2 23.1 0.079 10.5 23.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FapA PF03961.13 CBY10683.1 - 0.065 11.8 14.5 0.097 11.3 14.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A LCD1 PF09798.9 CBY10683.1 - 1.2 7.6 22.0 1.9 6.9 22.0 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Spherulin4 PF12138.8 CBY10683.1 - 1.7 8.2 5.3 9.3 5.8 0.0 2.7 2 1 1 3 3 3 0 Spherulation-specific family 4 PPP4R2 PF09184.11 CBY10683.1 - 2 7.9 24.2 3.8 7.0 24.2 1.4 1 0 0 1 1 1 0 PPP4R2 SlyX PF04102.12 CBY10683.1 - 2.6 8.8 8.6 0.93 10.2 1.0 3.1 1 1 2 3 3 3 0 SlyX Herpes_UL6 PF01763.16 CBY10683.1 - 4.1 5.8 13.5 3.7 5.9 12.5 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF913 PF06025.12 CBY10683.1 - 4.2 6.2 12.9 6.8 5.6 12.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 CBY10683.1 - 5.3 4.8 14.1 6.6 4.5 14.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 CBY10683.1 - 5.8 7.0 10.5 11 6.1 7.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) VWD PF00094.25 CBY10684.1 - 6.1e-31 107.8 13.5 3e-18 66.6 2.4 3.6 3 0 0 3 3 3 3 von Willebrand factor type D domain TIL PF01826.17 CBY10684.1 - 1.2e-10 41.5 33.8 1.2e-06 28.6 13.8 6.1 5 1 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain C8 PF08742.11 CBY10684.1 - 5.6e-07 29.9 13.0 8.1e-05 23.0 2.9 6.0 6 2 1 7 7 7 2 C8 domain RBD-FIP PF09457.10 CBY10685.1 - 8.8e-08 31.9 2.6 1.6e-07 31.1 2.6 1.4 1 0 0 1 1 1 1 FIP domain C2 PF00168.30 CBY10685.1 - 0.0083 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain PhoU PF01895.19 CBY10685.1 - 0.12 12.8 1.0 0.24 11.9 1.0 1.4 1 0 0 1 1 1 0 PhoU domain Sulfotransfer_1 PF00685.27 CBY10686.1 - 2.3e-06 27.3 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY10686.1 - 1.8e-05 25.2 0.0 0.011 16.1 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family DUF5395 PF17373.2 CBY10686.1 - 0.24 12.0 2.1 0.76 10.5 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5395) AA_permease_2 PF13520.6 CBY10687.1 - 3.3e-56 190.9 39.7 5.6e-55 186.9 39.7 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY10687.1 - 1.2e-15 57.1 34.4 1.9e-11 43.2 10.1 2.1 1 1 1 2 2 2 2 Amino acid permease Sulfotransfer_4 PF17784.1 CBY10688.1 - 2.8e-19 69.8 0.1 3e-19 69.7 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 CBY10689.1 - 1.5e-09 37.7 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY10689.1 - 4.5e-08 33.7 0.0 9.4e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family T4_Rnl2_C PF18043.1 CBY10689.1 - 0.13 12.4 0.2 0.34 11.1 0.2 1.6 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal adh_short PF00106.25 CBY10690.1 - 8e-33 113.5 0.0 1.3e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY10690.1 - 2.6e-23 82.8 0.0 3.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY10690.1 - 9.8e-05 22.3 0.1 0.00015 21.7 0.1 1.2 1 0 0 1 1 1 1 KR domain EGF PF00008.27 CBY10691.1 - 1.5e-28 98.7 158.9 1.2e-05 25.5 7.2 11.9 11 1 0 11 11 11 8 EGF-like domain hEGF PF12661.7 CBY10691.1 - 1.6e-17 63.4 108.8 0.0053 17.3 5.3 10.6 9 1 1 10 10 10 8 Human growth factor-like EGF Trypsin PF00089.26 CBY10691.1 - 7.4e-13 48.8 1.8 1.1e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 Trypsin Trefoil PF00088.18 CBY10691.1 - 4.6e-09 36.0 6.8 4.6e-09 36.0 6.8 11.7 5 4 7 12 12 12 3 Trefoil (P-type) domain EGF_2 PF07974.13 CBY10691.1 - 1.5e-06 28.4 177.8 0.0048 17.2 11.5 11.1 10 1 1 11 11 11 8 EGF-like domain DUF1986 PF09342.11 CBY10691.1 - 0.051 14.0 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) cEGF PF12662.7 CBY10691.1 - 0.23 11.4 85.2 0.36 10.8 2.5 9.5 8 0 0 8 8 8 0 Complement Clr-like EGF-like DSPc PF00782.20 CBY10693.1 - 8.6e-20 70.9 0.0 1.1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBY10693.1 - 0.00044 19.9 0.0 0.00053 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.6 CBY10693.1 - 0.045 14.2 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half MukE PF04288.13 CBY10693.1 - 0.14 11.1 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 MukE-like family Glyco_hydro_20 PF00728.22 CBY10694.1 - 9.8e-64 216.0 0.0 1.5e-63 215.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX_C PF03174.13 CBY10694.1 - 4.9e-05 23.2 0.0 9.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF2207 PF09972.9 CBY10695.1 - 0.01 14.6 1.8 0.011 14.5 1.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PIRT PF15099.6 CBY10695.1 - 0.031 13.8 0.4 0.036 13.7 0.4 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family zf-H2C2_2 PF13465.6 CBY10696.1 - 0.041 14.3 0.3 0.041 14.3 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double domain RhoGEF PF00621.20 CBY10697.1 - 1e-23 84.6 0.4 1.6e-23 83.9 0.4 1.3 1 0 0 1 1 1 1 RhoGEF domain CEP44 PF15007.6 CBY10697.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Macoilin PF09726.9 CBY10698.1 - 0.015 13.9 0.1 0.019 13.6 0.1 1.0 1 0 0 1 1 1 0 Macoilin family HOOK PF05622.12 CBY10698.1 - 0.02 13.1 0.5 0.024 12.8 0.5 1.0 1 0 0 1 1 1 0 HOOK protein TMF_DNA_bd PF12329.8 CBY10698.1 - 0.099 12.7 2.6 0.13 12.2 2.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DegT_DnrJ_EryC1 PF01041.17 CBY10698.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FAM216B PF15107.6 CBY10699.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 FAM216B protein family WW PF00397.26 CBY10700.1 - 1e-16 60.7 7.2 1.4e-10 41.1 0.7 2.7 2 0 0 2 2 2 2 WW domain Glyco_hydro_20 PF00728.22 CBY10700.1 - 0.031 13.7 0.2 0.037 13.4 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Trypsin_2 PF13365.6 CBY10701.1 - 1.1e-13 52.3 0.0 2.2e-13 51.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CBY10701.1 - 0.00046 20.1 0.6 0.0018 18.2 0.6 1.9 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.21 CBY10701.1 - 0.016 15.0 0.1 0.066 13.0 0.1 2.0 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S29 PF02907.15 CBY10701.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease DUF31 PF01732.16 CBY10701.1 - 0.25 10.8 10.9 0.37 10.3 0.0 3.3 2 1 0 3 3 3 0 Putative peptidase (DUF31) Mt_ATP-synt_D PF05873.12 CBY10702.1 - 0.003 17.4 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) PHM7_cyt PF14703.6 CBY10702.1 - 0.012 15.9 0.2 0.015 15.5 0.2 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter CHD5 PF04420.14 CBY10702.1 - 0.072 12.9 0.8 0.72 9.7 0.3 2.1 2 0 0 2 2 2 0 CHD5-like protein Annexin PF00191.20 CBY10703.1 - 2e-11 43.8 0.3 2.6e-11 43.4 0.3 1.2 1 0 0 1 1 1 1 Annexin Imm64 PF15600.6 CBY10703.1 - 0.012 15.4 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 64 Sacchrp_dh_C PF16653.5 CBY10704.1 - 2.6e-73 247.4 0.0 6.2e-73 246.2 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 CBY10704.1 - 7.8e-23 81.3 0.0 2.7e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 CBY10704.1 - 1.7e-19 70.4 2.1 3.6e-18 66.1 0.0 2.9 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CBY10704.1 - 0.00036 20.9 0.0 0.0046 17.4 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.6 CBY10704.1 - 0.0014 19.1 0.0 0.069 13.6 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain Shikimate_DH PF01488.20 CBY10704.1 - 0.002 18.2 0.0 0.0061 16.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CBY10704.1 - 0.027 13.9 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IF2_N PF04760.15 CBY10704.1 - 0.042 13.7 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region UDPG_MGDP_dh_N PF03721.14 CBY10704.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 CBY10704.1 - 0.099 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBY10704.1 - 0.13 12.8 1.7 1.2 9.7 0.1 3.2 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Annexin PF00191.20 CBY10705.1 - 4e-54 180.6 4.3 4.2e-20 71.6 0.2 3.1 3 0 0 3 3 3 3 Annexin Gal-3-0_sulfotr PF06990.11 CBY10706.1 - 3e-62 210.8 0.4 3.5e-62 210.6 0.4 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY10706.1 - 1.9e-05 24.7 0.2 1.9e-05 24.7 0.2 2.2 2 2 0 3 3 3 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 CBY10706.1 - 5.9e-05 23.6 0.1 0.00024 21.6 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY10706.1 - 0.0015 18.1 1.3 0.0058 16.1 1.3 2.1 1 1 0 1 1 1 1 Sulfotransferase domain CMAS PF02353.20 CBY10707.1 - 2.8e-35 122.0 1.6 4.2e-35 121.4 1.6 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CBY10707.1 - 1e-11 45.0 0.0 2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY10707.1 - 3.4e-11 43.1 0.0 7.8e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY10707.1 - 2.4e-10 41.0 0.0 5.7e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY10707.1 - 7.7e-10 39.4 0.0 2.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY10707.1 - 2.4e-09 37.0 0.0 7.5e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CBY10707.1 - 6.5e-08 33.1 0.0 1.4e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CBY10707.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 CBY10707.1 - 0.053 12.8 0.0 0.15 11.3 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase domain HLH PF00010.26 CBY10708.1 - 1.1e-15 57.3 3.0 2.2e-15 56.3 3.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 CBY10708.1 - 0.69 9.9 6.5 0.75 9.7 6.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 CBY10709.1 - 3.8e-26 91.9 17.2 3.8e-26 91.9 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5337 PF17272.2 CBY10709.1 - 2.1 8.3 6.2 0.95 9.3 0.8 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Glyco_transf_7C PF02709.14 CBY10710.1 - 6.1e-27 93.1 0.2 8.6e-27 92.6 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase ATP-gua_Ptrans PF00217.19 CBY10711.1 - 2.2e-60 203.8 0.0 2.9e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY10711.1 - 8.5e-24 83.7 0.0 1.4e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Csm1_N PF18504.1 CBY10712.1 - 0.0053 17.1 0.1 0.0087 16.4 0.1 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain TPR_MLP1_2 PF07926.12 CBY10712.1 - 0.013 15.6 1.3 0.019 15.1 1.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ax_dynein_light PF10211.9 CBY10712.1 - 0.015 15.3 0.9 0.018 15.0 0.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain FliD_C PF07195.12 CBY10712.1 - 0.024 14.0 0.1 0.032 13.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Med9 PF07544.13 CBY10712.1 - 0.075 13.1 0.6 0.13 12.4 0.6 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4407 PF14362.6 CBY10712.1 - 0.078 12.3 0.3 0.079 12.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 CBY10712.1 - 1.8 8.9 4.8 3.1 8.2 4.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 bZIP_2 PF07716.15 CBY10713.1 - 8.8e-10 38.5 10.4 8.8e-10 38.5 10.4 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY10713.1 - 9.1e-05 22.5 7.4 9.1e-05 22.5 7.4 2.4 1 1 1 2 2 2 1 bZIP transcription factor Cas9_b_hairpin PF17893.1 CBY10714.1 - 0.046 13.5 0.0 3.1 7.7 0.0 2.4 1 1 1 2 2 2 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain DUF1971 PF09313.11 CBY10714.1 - 0.071 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Pkinase PF00069.25 CBY10715.1 - 3.6e-41 141.3 0.1 5.3e-41 140.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10715.1 - 3e-20 72.6 0.1 4.2e-20 72.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_48 PF17906.1 CBY10715.1 - 0.061 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Phospholip_A2_1 PF00068.19 CBY10716.1 - 6.5e-14 52.4 6.5 6.5e-14 52.4 6.5 2.0 2 0 0 2 2 2 1 Phospholipase A2 GGDEF_2 PF17853.1 CBY10716.1 - 0.049 13.9 0.1 0.08 13.2 0.1 1.5 1 0 0 1 1 1 0 GGDEF-like domain fn3 PF00041.21 CBY10717.1 - 4.2e-12 46.2 1.0 1.4e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY10717.1 - 0.068 13.7 0.6 0.48 11.0 0.1 2.2 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 CBY10718.1 - 9.9e-08 32.2 0.3 0.00036 20.8 0.3 3.1 2 2 1 3 3 3 2 Fibronectin type III domain Nop10p PF04135.12 CBY10718.1 - 0.19 11.8 1.9 0.71 10.0 0.1 2.5 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family TMEM154 PF15102.6 CBY10719.1 - 1.2e-06 28.5 4.1 1.2e-06 28.5 4.1 7.3 1 1 3 5 5 2 1 TMEM154 protein family EphA2_TM PF14575.6 CBY10719.1 - 0.0039 18.0 0.1 0.0086 16.9 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 CBY10719.1 - 0.018 15.3 3.1 0.018 15.3 3.1 3.4 3 2 2 5 5 5 0 Wnt and FGF inhibitory regulator PRIMA1 PF16101.5 CBY10719.1 - 0.018 15.0 0.4 0.042 13.9 0.4 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMEM132D_C PF15706.5 CBY10719.1 - 0.019 14.7 0.2 0.056 13.2 0.2 1.8 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Cadherin_C_2 PF16492.5 CBY10719.1 - 0.02 15.7 0.9 0.12 13.1 0.1 2.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF3481 PF11980.8 CBY10719.1 - 0.043 13.5 0.2 0.097 12.4 0.2 1.6 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein TrbL PF04610.14 CBY10719.1 - 0.069 12.9 4.3 0.18 11.6 4.3 1.7 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein MLANA PF14991.6 CBY10719.1 - 0.11 12.8 0.1 0.47 10.8 0.1 2.1 1 0 0 1 1 1 0 Protein melan-A Adeno_E3_CR2 PF02439.15 CBY10719.1 - 0.17 11.7 11.5 0.35 10.6 11.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Sigma_reg_N PF13800.6 CBY10719.1 - 0.71 10.2 5.3 0.29 11.5 0.9 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4969 PF16339.5 CBY10719.1 - 4.6 7.7 7.5 1.9 8.9 2.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) Stevor PF17410.2 CBY10719.1 - 9.4 5.7 21.6 0.025 14.1 3.0 3.2 2 1 1 3 3 3 0 Subtelomeric Variable Open Reading frame zf-C4 PF00105.18 CBY10720.1 - 2.8e-27 95.0 22.7 4.6e-27 94.3 22.7 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY10720.1 - 3.5e-10 39.8 2.1 6.4e-10 38.9 2.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DDA1 PF10172.9 CBY10720.1 - 0.021 15.1 0.2 0.16 12.3 0.1 2.5 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase HoxA13_N PF12284.8 CBY10720.1 - 0.067 13.8 0.9 0.19 12.4 0.9 1.7 1 0 0 1 1 1 0 Hox protein A13 N terminal DUF4026 PF13218.6 CBY10721.1 - 0.15 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) zf-H2C2_2 PF13465.6 CBY10723.1 - 2.1e-09 37.4 35.0 0.00057 20.2 10.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY10723.1 - 1.1e-06 28.7 34.5 0.0041 17.5 8.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY10723.1 - 2.8e-06 27.7 30.1 0.026 15.3 1.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY10723.1 - 0.0039 17.2 4.8 0.0039 17.2 4.8 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 CBY10723.1 - 0.082 13.0 0.0 0.082 13.0 0.0 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Acyltransf_C PF16076.5 CBY10723.1 - 0.088 12.9 0.8 8 6.6 0.6 2.7 1 1 0 1 1 1 0 Acyltransferase C-terminus DUF1966 PF09260.11 CBY10723.1 - 0.091 13.0 0.4 0.2 11.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) zf-met PF12874.7 CBY10723.1 - 0.15 12.5 15.3 0.82 10.1 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY10723.1 - 0.54 10.6 0.1 0.54 10.6 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 CBY10723.1 - 0.66 9.9 11.9 1.4 8.9 0.3 3.5 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ALMS_motif PF15309.6 CBY10723.1 - 0.75 10.3 7.6 10 6.6 0.6 2.6 2 0 0 2 2 2 0 ALMS motif zf-C2HC_2 PF13913.6 CBY10723.1 - 1 9.3 23.7 0.81 9.7 1.6 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-BED PF02892.15 CBY10723.1 - 1.1 9.3 16.5 1.4 9.0 1.1 3.4 1 1 2 3 3 3 0 BED zinc finger zf-CHCC PF10276.9 CBY10723.1 - 4 7.6 14.7 0.28 11.3 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger domain Chromo PF00385.24 CBY10724.1 - 8.4e-22 76.8 10.4 1.1e-11 44.4 0.1 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.19 CBY10724.1 - 0.0011 18.6 23.1 0.097 12.6 4.1 4.4 2 1 1 3 3 3 3 AT hook motif Tudor-knot PF11717.8 CBY10724.1 - 0.0018 18.1 7.1 0.17 11.8 0.1 2.7 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.6 CBY10724.1 - 0.063 13.5 0.9 2.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 ELM2 PF01448.24 CBY10724.1 - 0.58 10.9 0.0 0.58 10.9 0.0 3.5 3 1 0 3 3 3 0 ELM2 domain 7tm_1 PF00001.21 CBY10725.1 - 7.8e-49 166.4 9.6 1.1e-48 165.9 9.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MRP-63 PF14978.6 CBY10726.1 - 1.7e-05 25.3 0.6 0.00028 21.4 0.0 2.4 2 1 0 2 2 2 1 Mitochondrial ribosome protein 63 Neuralized PF07177.12 CBY10727.1 - 4e-26 91.8 0.0 5.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Neuralized Ank_4 PF13637.6 CBY10728.1 - 2.9e-23 81.9 0.3 1.7e-11 44.4 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY10728.1 - 8.4e-23 80.1 0.4 5.5e-09 36.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY10728.1 - 1.8e-22 79.7 0.1 4.4e-12 46.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY10728.1 - 3e-16 59.0 0.1 1.6e-08 34.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CBY10728.1 - 8.5e-12 44.2 0.1 3.7e-05 23.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Trypsin PF00089.26 CBY10729.1 - 3.1e-78 262.6 4.1 7.9e-38 130.5 0.2 3.1 3 0 0 3 3 3 3 Trypsin CUB PF00431.20 CBY10729.1 - 6.9e-21 74.7 0.2 2.4e-20 72.9 0.1 2.0 2 0 0 2 2 2 1 CUB domain DUF1986 PF09342.11 CBY10729.1 - 8.6e-09 35.8 0.0 1.5e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Transformer PF06495.11 CBY10731.1 - 0.082 13.0 4.1 0.14 12.2 4.1 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein DUF812 PF05667.11 CBY10731.1 - 0.54 9.1 30.8 0.78 8.5 30.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.11 CBY10731.1 - 5.1 5.9 38.3 3.8 6.3 13.2 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein RNA_pol_Rpb2_1 PF04563.15 CBY10732.1 - 7.3e-32 110.5 0.1 1.3e-31 109.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_6 PF00562.28 CBY10732.1 - 1e-26 94.0 0.0 1.6e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 CBY10732.1 - 9e-26 89.8 0.0 2.3e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CBY10732.1 - 1e-14 54.3 0.0 2.6e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CBY10732.1 - 0.00041 20.0 0.0 0.00081 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Vmethyltransf_C PF08456.10 CBY10733.1 - 0.041 13.5 2.9 0.048 13.2 2.9 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal Ferlin_C PF16165.5 CBY10733.1 - 2.1 8.3 7.9 2.9 7.8 7.9 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Peptidase_S49_N PF08496.10 CBY10733.1 - 8.8 6.4 12.0 1.3 9.0 7.8 1.7 1 1 1 2 2 2 0 Peptidase family S49 N-terminal PCI PF01399.27 CBY10735.1 - 2.6e-14 53.6 0.6 6.1e-14 52.4 0.1 1.9 2 0 0 2 2 2 1 PCI domain DUF4761 PF15958.5 CBY10736.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) DASH_Ask1 PF08655.10 CBY10736.1 - 0.055 13.4 0.5 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 DASH complex subunit Ask1 Ammonium_transp PF00909.21 CBY10737.1 - 1e-87 294.4 17.0 1.3e-87 294.2 17.0 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Sulfate_transp PF00916.20 CBY10738.1 - 9.3e-51 172.8 12.1 6.4e-50 170.0 12.1 1.9 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CBY10738.1 - 2e-05 24.2 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CBY10738.1 - 0.0019 18.6 2.5 0.0019 18.6 2.5 2.7 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily Pneumo_NS1 PF03438.13 CBY10738.1 - 0.064 13.4 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Pneumovirus NS1 protein Trefoil PF00088.18 CBY10739.1 - 1.2e-21 76.3 42.5 2.8e-08 33.5 1.5 5.4 5 0 0 5 5 5 5 Trefoil (P-type) domain DUF5442 PF17514.2 CBY10739.1 - 0.037 14.2 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5442) SLT PF01464.20 CBY10740.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.5 1 1 0 1 1 1 1 Transglycosylase SLT domain Cadherin PF00028.17 CBY10741.1 - 0.00017 21.9 11.8 7.4 7.1 0.0 7.7 8 1 0 8 8 8 3 Cadherin domain Ion_trans_2 PF07885.16 CBY10742.1 - 1.4e-11 44.2 4.2 1.4e-11 44.2 4.2 1.6 1 1 1 2 2 2 2 Ion channel Trypsin PF00089.26 CBY10743.1 - 1.3e-44 152.6 4.8 2.1e-44 152.0 4.8 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 CBY10743.1 - 2.9e-28 98.4 5.2 3.1e-13 50.0 0.2 3.9 4 0 0 4 4 4 3 CUB domain Trypsin_2 PF13365.6 CBY10743.1 - 8.8e-06 26.7 0.1 2.7e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain AgrB PF04647.15 CBY10744.1 - 0.019 14.3 3.7 0.026 13.8 3.7 1.1 1 0 0 1 1 1 0 Accessory gene regulator B UPF0370 PF13980.6 CBY10744.1 - 6.8 6.8 7.8 1.9 8.6 0.0 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0370) Pkinase PF00069.25 CBY10745.1 - 1.8e-61 207.9 0.0 6.7e-61 206.0 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10745.1 - 1.7e-34 119.3 0.0 3.7e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGEF PF00621.20 CBY10746.1 - 3.4e-16 60.0 1.6 3.8e-16 59.8 0.1 2.0 2 0 0 2 2 2 1 RhoGEF domain TFIIE_beta PF02186.15 CBY10746.1 - 10 6.5 6.8 3.8 7.9 0.3 3.2 4 0 0 4 4 4 0 TFIIE beta subunit core domain G_glu_transpept PF01019.21 CBY10748.1 - 1.1e-145 486.3 0.0 1.3e-145 486.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase T-box PF00907.22 CBY10749.1 - 3.6e-76 255.5 0.1 3.6e-76 255.5 0.1 1.8 2 0 0 2 2 2 1 T-box DUF2057 PF09829.9 CBY10749.1 - 0.011 15.9 3.5 0.54 10.4 1.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Plectin PF00681.20 CBY10750.1 - 1.7e-33 114.2 1.9 1.1e-15 57.2 0.1 4.9 5 0 0 5 5 5 4 Plectin repeat Trypsin PF00089.26 CBY10751.1 - 2.5e-44 151.7 0.2 5.3e-44 150.7 0.0 1.6 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 CBY10751.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 CUB domain DUF1986 PF09342.11 CBY10751.1 - 0.04 14.3 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) WAK_assoc PF14380.6 CBY10751.1 - 0.077 13.7 0.2 0.29 11.9 0.0 2.0 2 0 0 2 2 2 0 Wall-associated receptor kinase C-terminal Baculo_LEF-10 PF07206.11 CBY10751.1 - 0.15 12.2 1.7 2.3 8.4 0.0 2.8 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) T-box PF00907.22 CBY10752.1 - 3.2e-43 148.1 0.2 3.2e-43 148.1 0.2 2.2 2 0 0 2 2 2 1 T-box Macoilin PF09726.9 CBY10752.1 - 3.7 6.0 10.7 5.7 5.4 10.7 1.3 1 0 0 1 1 1 0 Macoilin family DUF2633 PF11119.8 CBY10754.1 - 0.38 10.7 4.9 0.88 9.5 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2633) VWC PF00093.18 CBY10755.1 - 3.9e-16 59.1 83.6 6.5e-07 29.6 15.9 10.6 7 3 3 10 10 10 4 von Willebrand factor type C domain Antistasin PF02822.14 CBY10755.1 - 3.8e-15 56.2 36.9 5e-10 39.8 6.8 14.2 12 2 1 13 13 13 3 Antistasin family PSP94 PF05825.11 CBY10755.1 - 0.0085 16.6 4.7 0.0085 16.6 4.7 7.7 4 2 3 7 7 7 2 Beta-microseminoprotein (PSP-94) CFC PF09443.10 CBY10755.1 - 0.02 14.7 2.8 0.02 14.7 2.8 9.7 8 0 0 8 8 8 0 Cripto_Frl-1_Cryptic (CFC) SHIPPO-rpt PF07004.12 CBY10757.1 - 2.6e-12 47.0 27.0 0.015 16.2 1.3 7.0 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat BBE PF08031.12 CBY10757.1 - 0.01 15.9 0.0 5.2 7.2 0.0 2.9 2 0 0 2 2 2 0 Berberine and berberine like Dynein_AAA_lid PF17852.1 CBY10757.1 - 0.044 13.9 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Homeodomain PF00046.29 CBY10759.1 - 1.3e-13 50.5 1.1 2.6e-13 49.6 1.1 1.5 1 0 0 1 1 1 1 Homeodomain Galactosyl_T PF01762.21 CBY10760.1 - 0.00025 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase LIN37 PF15306.6 CBY10760.1 - 0.055 13.7 2.1 0.082 13.1 2.1 1.2 1 0 0 1 1 1 0 LIN37 EGF_3 PF12947.7 CBY10761.1 - 3.3e-05 24.0 6.1 6.5e-05 23.0 6.1 1.5 1 0 0 1 1 1 1 EGF domain EGF_MSP1_1 PF12946.7 CBY10761.1 - 0.014 15.4 6.2 0.026 14.6 6.2 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 EGF PF00008.27 CBY10762.1 - 9.8e-23 80.1 64.9 1.8e-08 34.5 9.3 5.1 5 0 0 5 5 5 4 EGF-like domain hEGF PF12661.7 CBY10762.1 - 9.9e-09 35.5 58.0 0.00084 19.9 6.0 6.0 5 1 1 6 6 6 4 Human growth factor-like EGF EGF_2 PF07974.13 CBY10762.1 - 4.5e-06 26.9 67.3 0.0012 19.1 11.5 4.9 4 0 0 4 4 4 3 EGF-like domain Laminin_EGF PF00053.24 CBY10762.1 - 2 8.7 60.9 1.3 9.2 6.7 5.3 3 1 3 6 6 6 0 Laminin EGF domain PfkB PF00294.24 CBY10764.1 - 1.9e-13 50.4 0.1 1.9e-12 47.2 0.1 1.9 1 1 1 2 2 2 2 pfkB family carbohydrate kinase EF-hand_1 PF00036.32 CBY10766.1 - 2e-05 23.8 0.5 3.4e-05 23.1 0.5 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CBY10766.1 - 4.2e-05 23.3 0.3 5e-05 23.1 0.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 CBY10766.1 - 0.00053 20.4 0.1 0.00058 20.3 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY10766.1 - 0.0076 16.1 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain VWA_3 PF13768.6 CBY10767.1 - 2.7e-11 43.7 0.0 4.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CBY10767.1 - 0.00018 21.8 0.0 0.00032 21.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF5064 PF16703.5 CBY10767.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5064) Glycos_transf_2 PF00535.26 CBY10768.1 - 5.7e-14 52.3 0.0 8.2e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 RVT_1 PF00078.27 CBY10769.1 - 6.7e-15 55.2 0.0 3e-11 43.3 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) PmbA_TldD PF01523.16 CBY10769.1 - 0.0068 16.3 0.0 0.045 13.6 0.0 2.3 2 0 0 2 2 2 1 Putative modulator of DNA gyrase Med30 PF11315.8 CBY10769.1 - 0.032 14.4 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 Mediator complex subunit 30 PALP PF00291.25 CBY10770.1 - 8.3e-75 251.9 0.2 1.1e-74 251.5 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 CBY10770.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 ACT domain Glycos_transf_2 PF00535.26 CBY10772.1 - 2.4e-14 53.5 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 MH2 PF03166.14 CBY10775.1 - 5.8e-46 157.1 0.4 5.8e-46 157.1 0.4 1.6 2 0 0 2 2 2 1 MH2 domain MH1 PF03165.16 CBY10775.1 - 2.9e-11 43.5 0.7 6e-11 42.5 0.7 1.5 1 0 0 1 1 1 1 MH1 domain Nitrophorin PF02087.15 CBY10775.1 - 0.049 13.6 0.5 0.089 12.8 0.2 1.5 2 0 0 2 2 2 0 Nitrophorin MH1 PF03165.16 CBY10776.1 - 0.0046 17.1 0.1 0.012 15.8 0.1 1.6 2 0 0 2 2 2 1 MH1 domain TAN PF11640.8 CBY10776.1 - 0.081 13.0 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Astacin PF01400.24 CBY10777.1 - 9.9e-58 194.9 0.0 1.6e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TSP_1 PF00090.19 CBY10777.1 - 2e-05 24.7 9.1 2e-05 24.7 9.1 2.5 2 0 0 2 2 2 1 Thrombospondin type 1 domain Sushi PF00084.20 CBY10778.1 - 0.64 10.7 5.9 0.47 11.1 0.6 3.1 3 0 0 3 3 3 0 Sushi repeat (SCR repeat) Sushi PF00084.20 CBY10780.1 - 0.2 12.3 5.0 0.22 12.1 0.5 2.8 3 0 0 3 3 3 0 Sushi repeat (SCR repeat) Meis_PKNOX_N PF16493.5 CBY10781.1 - 3.4e-38 129.8 0.5 7.1e-38 128.8 0.5 1.6 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 CBY10781.1 - 8.2e-20 70.4 1.3 2.1e-19 69.1 1.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY10781.1 - 1e-08 34.9 1.2 1e-08 34.9 1.2 2.1 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 CBY10781.1 - 0.079 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Epimerase PF01370.21 CBY10783.1 - 0.0051 16.3 0.1 0.0076 15.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RRM_1 PF00076.22 CBY10784.1 - 1.1e-26 92.4 1.8 9e-16 57.5 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY10784.1 - 3.6e-10 39.8 0.4 7.4e-05 22.8 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CBY10784.1 - 0.0023 17.9 0.0 0.077 13.0 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY10784.1 - 0.039 14.0 0.1 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 RNA binding motif DER1 PF04511.15 CBY10785.1 - 2.7e-52 177.5 12.4 3.1e-52 177.3 12.4 1.0 1 0 0 1 1 1 1 Der1-like family DUF983 PF06170.12 CBY10785.1 - 7.8 7.0 13.3 15 6.1 6.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF983) zf-CpG_bind_C PF12269.8 CBY10786.1 - 9.3e-72 241.6 7.7 9.3e-72 241.6 7.7 2.3 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain PHD PF00628.29 CBY10786.1 - 2.9e-10 39.9 7.7 2.9e-10 39.9 7.7 3.4 3 1 1 4 4 4 1 PHD-finger DUF1644 PF07800.12 CBY10786.1 - 0.004 17.2 14.4 0.0087 16.1 8.9 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1644) Ald_Xan_dh_C2 PF02738.18 CBY10787.1 - 4.1e-188 626.3 0.0 5.8e-188 625.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 CBY10787.1 - 1.4e-36 125.8 0.0 2.9e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 CBY10787.1 - 7.5e-30 102.8 0.1 1.7e-29 101.6 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 CBY10787.1 - 2e-26 92.1 0.0 1.2e-25 89.7 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 CBY10787.1 - 4e-26 91.5 0.1 1.3e-25 89.9 0.1 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 CBY10787.1 - 2.6e-09 36.9 1.0 9.2e-09 35.1 0.4 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 CBY10787.1 - 0.66 9.8 5.2 2.2 8.2 5.2 1.9 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Not1 PF04054.15 CBY10788.1 - 0.029 13.3 0.0 0.063 12.2 0.0 1.5 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 LPD39 PF18858.1 CBY10788.1 - 0.082 13.0 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 DUF1053 PF06327.14 CBY10788.1 - 0.085 13.4 0.5 0.085 13.4 0.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) YxiJ PF14176.6 CBY10788.1 - 0.52 10.8 4.2 7.9 7.0 0.1 2.5 2 1 0 2 2 2 0 YxiJ-like protein PSI PF01437.25 CBY10789.1 - 1.9e-07 31.5 1.8 4.3e-07 30.4 1.8 1.6 1 0 0 1 1 1 1 Plexin repeat TMIE PF16038.5 CBY10789.1 - 0.033 14.0 1.3 0.043 13.6 0.2 1.7 2 0 0 2 2 2 0 TMIE protein Myosin_tail_1 PF01576.19 CBY10790.1 - 1.2e-05 23.4 25.9 1.3e-05 23.3 25.9 1.0 1 0 0 1 1 1 1 Myosin tail Phage_lysozyme2 PF18013.1 CBY10790.1 - 0.016 15.2 6.4 0.018 15.0 6.4 1.2 1 0 0 1 1 1 0 Phage tail lysozyme Synaptobrevin PF00957.21 CBY10790.1 - 0.04 13.7 2.0 0.04 13.7 2.0 2.1 1 1 1 2 2 2 0 Synaptobrevin Rootletin PF15035.6 CBY10790.1 - 0.056 13.5 20.0 0.039 14.0 18.7 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.11 CBY10790.1 - 0.18 12.1 1.1 0.37 11.1 1.0 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 CBY10790.1 - 0.2 11.0 13.9 0.23 10.7 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GCN5L1 PF06320.13 CBY10790.1 - 0.33 11.1 12.9 0.49 10.6 12.0 1.6 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) TMPIT PF07851.13 CBY10790.1 - 0.44 9.7 12.8 0.55 9.4 12.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein CotJB PF12652.7 CBY10790.1 - 0.74 10.1 5.9 0.49 10.7 3.7 1.8 1 1 1 2 2 2 0 CotJB protein DUF3810 PF12725.7 CBY10790.1 - 1 8.7 5.2 1.1 8.6 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3450 PF11932.8 CBY10790.1 - 1.1 8.5 15.2 1.1 8.5 14.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 CBY10790.1 - 1.4 9.4 10.5 2.4 8.7 10.5 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Phage_GPO PF05929.11 CBY10790.1 - 1.8 8.1 13.1 2 7.9 13.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6_N PF17675.1 CBY10790.1 - 2.9 8.4 28.8 5.9 7.4 28.8 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region CorA PF01544.18 CBY10790.1 - 5 6.4 10.8 8.7 5.6 10.8 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Fmp27_WPPW PF10359.9 CBY10790.1 - 5.4 5.7 19.7 12 4.7 19.7 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Uds1 PF15456.6 CBY10790.1 - 6.6 6.9 22.3 26 5.0 22.3 1.8 1 1 0 1 1 1 0 Up-regulated During Septation ERM PF00769.19 CBY10790.1 - 6.7 6.5 30.1 27 4.5 30.1 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Rho_Binding PF08912.11 CBY10790.1 - 7.9 7.4 25.6 22 6.0 5.3 3.0 2 1 0 2 2 2 0 Rho Binding DUF724 PF05266.14 CBY10790.1 - 8.7 6.1 17.3 10 5.9 17.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FUSC PF04632.12 CBY10790.1 - 8.9 4.7 6.3 9.9 4.6 6.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family kleA_kleC PF17383.2 CBY10790.1 - 9.2 6.7 11.2 2.7 8.4 5.8 2.1 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A SRI PF08236.11 CBY10792.1 - 0.11 12.7 0.1 0.3 11.3 0.1 1.7 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Kelch_2 PF07646.15 CBY10793.1 - 0.091 12.8 0.0 0.74 9.9 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Trypsin PF00089.26 CBY10794.1 - 1.9e-38 132.5 0.0 1.9e-38 132.5 0.0 1.6 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 CBY10794.1 - 3.3e-06 27.5 0.0 9.3e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) UPAR_LY6_2 PF16975.5 CBY10794.1 - 0.0011 19.1 2.4 0.0011 19.1 2.4 1.7 2 0 0 2 2 2 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Trypsin_2 PF13365.6 CBY10794.1 - 0.054 14.4 0.0 0.13 13.2 0.0 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain HTH_43 PF09904.9 CBY10796.1 - 0.094 12.7 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix Fibrinogen_C PF00147.18 CBY10797.1 - 7.5e-18 65.1 0.7 1.3e-17 64.4 0.7 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Phage_Gp23 PF10669.9 CBY10797.1 - 0.028 14.8 7.5 0.071 13.4 7.5 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) COG2 PF06148.11 CBY10797.1 - 0.62 10.1 8.2 3.2 7.8 0.9 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FSA_C PF10479.9 CBY10797.1 - 2.1 6.3 11.7 3 5.9 11.7 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CHGN PF05679.16 CBY10798.1 - 2.4e-30 105.8 0.4 3.9e-30 105.2 0.4 1.3 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase SRF-TF PF00319.18 CBY10798.1 - 3.3e-24 84.1 0.4 6.4e-24 83.2 0.4 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Glyco_transf_7C PF02709.14 CBY10798.1 - 7.2e-06 25.6 0.0 1.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Fringe PF02434.16 CBY10798.1 - 6.9e-05 22.4 0.4 6.9e-05 22.4 0.4 2.4 3 0 0 3 3 3 1 Fringe-like Galactosyl_T PF01762.21 CBY10798.1 - 0.0056 16.5 0.4 0.057 13.2 0.0 2.7 3 1 0 3 3 3 1 Galactosyltransferase GHD PF17834.1 CBY10798.1 - 0.044 13.8 0.3 0.25 11.4 0.1 2.3 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase Ets PF00178.22 CBY10799.1 - 7.8e-32 109.6 0.1 1.7e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 Ets-domain DUF3484 PF11983.8 CBY10799.1 - 6.2 8.0 6.5 5.3 8.2 0.2 3.1 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Ets PF00178.22 CBY10800.1 - 6.3e-35 119.5 0.1 1.3e-34 118.5 0.1 1.6 1 0 0 1 1 1 1 Ets-domain DUF3484 PF11983.8 CBY10800.1 - 0.19 12.9 1.3 4.3 8.5 0.2 2.6 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Rhodanese PF00581.20 CBY10802.1 - 2.5e-10 40.8 0.0 5e-10 39.8 0.0 1.5 2 0 0 2 2 2 1 Rhodanese-like domain CENP-C_C PF11699.8 CBY10802.1 - 0.089 13.0 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Mif2/CENP-C like DUF2550 PF10739.9 CBY10802.1 - 0.14 12.2 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) Sulfotransfer_2 PF03567.14 CBY10803.1 - 1.3e-09 38.4 0.1 1.5e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Na_Ca_ex PF01699.24 CBY10804.1 - 4e-47 160.0 30.8 2.3e-24 86.1 12.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 CBY10804.1 - 2.7e-43 146.2 3.2 8.2e-22 77.3 0.6 2.5 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex_C PF16494.5 CBY10804.1 - 0.001 19.6 0.1 0.0023 18.4 0.1 1.6 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain DUF2781 PF10914.8 CBY10804.1 - 0.61 10.5 6.3 0.19 12.1 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) DUF1661 PF07877.11 CBY10805.1 - 0.031 13.9 1.2 0.039 13.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) WBP-1 PF11669.8 CBY10805.1 - 0.17 12.6 6.3 0.15 12.7 3.6 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 Na_Ca_ex PF01699.24 CBY10806.1 - 4.5e-23 81.9 10.6 7.1e-23 81.2 10.6 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Calx-beta PF03160.14 CBY10806.1 - 2.7e-17 62.7 0.0 5.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Calx-beta domain DUF2781 PF10914.8 CBY10806.1 - 0.041 14.3 0.5 0.075 13.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) AMP-binding PF00501.28 CBY10807.1 - 1.8e-51 175.1 0.1 5e-51 173.6 0.1 1.6 2 0 0 2 2 2 1 AMP-binding enzyme DUF1786 PF08735.10 CBY10807.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) AMP-binding PF00501.28 CBY10808.1 - 4.7e-16 58.4 0.0 5.5e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme YcaO_C PF18381.1 CBY10808.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 YcaO cyclodehydratase C-terminal domain Pkinase PF00069.25 CBY10809.1 - 9.1e-09 35.1 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10809.1 - 9e-06 25.1 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.6 CBY10809.1 - 0.041 14.1 7.6 6.9 6.9 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3896) DUF1827 PF08860.10 CBY10809.1 - 0.21 11.8 2.1 12 6.2 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1827) Sulfotransfer_1 PF00685.27 CBY10810.1 - 2.3e-06 27.3 0.2 2.6e-06 27.1 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.14 CBY10810.1 - 4e-06 26.9 0.1 6.3e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 CBY10810.1 - 0.0046 17.4 0.1 0.0056 17.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF3139 PF11337.8 CBY10811.1 - 0.17 12.6 0.1 0.17 12.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3139) CytochromB561_N PF09786.9 CBY10811.1 - 0.61 9.0 1.7 0.74 8.7 1.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Kelch_6 PF13964.6 CBY10812.1 - 5e-09 36.1 0.0 0.038 14.3 0.0 3.2 2 1 1 3 3 3 3 Kelch motif Kelch_1 PF01344.25 CBY10812.1 - 1.5e-08 34.0 0.1 0.089 12.4 0.0 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 CBY10812.1 - 4.8e-06 26.4 0.0 0.017 15.1 0.0 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY10812.1 - 0.00076 19.4 0.1 0.52 10.4 0.0 2.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY10812.1 - 0.0023 17.9 0.2 0.45 10.6 0.1 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain SANTA PF09133.10 CBY10812.1 - 0.022 15.2 0.0 0.044 14.3 0.0 1.5 1 0 0 1 1 1 0 SANTA (SANT Associated) Kelch_3 PF13415.6 CBY10812.1 - 0.035 14.4 0.3 0.85 10.0 0.0 2.6 3 0 0 3 3 3 0 Galactose oxidase, central domain INPP5B_PH PF16776.5 CBY10813.1 - 0.024 14.3 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain COesterase PF00135.28 CBY10814.1 - 4.4e-72 243.6 2.0 1.3e-71 242.1 2.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY10814.1 - 2.8e-10 40.4 0.3 8.6e-10 38.8 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY10814.1 - 0.014 14.9 0.1 0.033 13.6 0.1 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CBY10814.1 - 0.039 12.9 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme CHGN PF05679.16 CBY10816.1 - 1.4e-61 208.9 0.5 1.1e-46 159.8 0.0 2.1 1 1 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY10816.1 - 3.2e-10 39.5 0.3 6.7e-10 38.5 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Fringe PF02434.16 CBY10816.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Fringe-like Glyco_tranf_2_2 PF10111.9 CBY10816.1 - 0.022 14.2 0.0 0.88 9.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase like family 2 IRF PF00605.17 CBY10816.1 - 0.082 13.2 0.8 0.19 12.0 0.3 1.8 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Spore_III_AB PF09548.10 CBY10816.1 - 0.16 12.1 0.2 0.27 11.3 0.2 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) LIM PF00412.22 CBY10818.1 - 6.5e-21 74.3 48.7 2e-07 31.1 16.9 3.5 3 0 0 3 3 3 3 LIM domain Endonuc_Holl PF10107.9 CBY10819.1 - 0.0023 17.8 2.3 0.0031 17.4 2.3 1.2 1 0 0 1 1 1 1 Endonuclease related to archaeal Holliday junction resolvase HBM PF16591.5 CBY10819.1 - 0.005 16.3 1.0 0.006 16.1 1.0 1.1 1 0 0 1 1 1 1 Helical bimodular sensor domain GIT1_C PF12205.8 CBY10819.1 - 0.0063 16.6 1.4 0.011 15.8 1.4 1.4 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term Uds1 PF15456.6 CBY10819.1 - 0.014 15.6 1.9 0.014 15.6 1.9 1.6 2 0 0 2 2 2 0 Up-regulated During Septation DUF1018 PF06252.12 CBY10819.1 - 0.018 16.0 0.8 0.025 15.6 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) DUF2383 PF09537.10 CBY10819.1 - 0.02 15.2 0.8 0.029 14.7 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2383) FAS_meander PF17951.1 CBY10819.1 - 0.028 14.2 0.7 0.24 11.2 0.5 1.9 1 1 1 2 2 2 0 Fatty acid synthase meander beta sheet domain TetR_C_8 PF14278.6 CBY10819.1 - 0.032 14.3 1.9 0.033 14.3 1.3 1.4 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region DUF365 PF04033.12 CBY10819.1 - 0.04 14.2 2.1 0.057 13.7 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Phage_GPO PF05929.11 CBY10819.1 - 0.052 13.2 3.9 0.065 12.8 3.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Tup_N PF08581.10 CBY10819.1 - 0.08 13.3 4.7 0.08 13.3 3.8 1.5 2 0 0 2 2 1 0 Tup N-terminal DUF1910 PF08928.10 CBY10819.1 - 0.083 12.9 2.0 0.12 12.3 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) MCPsignal PF00015.21 CBY10819.1 - 0.1 12.4 3.3 0.28 11.0 1.4 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3870 PF12986.7 CBY10819.1 - 0.1 12.8 1.2 0.19 12.0 0.5 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3870) SH3BP5 PF05276.14 CBY10819.1 - 0.17 11.7 6.7 0.29 10.9 6.7 1.5 1 1 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) 4HB_MCP_1 PF12729.7 CBY10819.1 - 0.23 11.0 7.5 0.099 12.2 5.5 1.5 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF1492 PF07374.11 CBY10819.1 - 0.23 11.6 3.7 0.24 11.6 2.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1492) K_trans PF02705.16 CBY10819.1 - 0.31 9.5 0.8 0.31 9.5 0.8 1.0 1 0 0 1 1 1 0 K+ potassium transporter HMMR_N PF15905.5 CBY10820.1 - 0.001 18.7 1.6 0.0011 18.5 1.6 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF4798 PF16055.5 CBY10820.1 - 0.0017 18.6 0.2 0.0021 18.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4798) ASL_C PF08328.11 CBY10820.1 - 0.0025 17.9 0.3 0.0026 17.8 0.3 1.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Syntaxin_2 PF14523.6 CBY10820.1 - 0.0046 17.3 2.4 0.0084 16.5 2.1 1.6 1 1 0 1 1 1 1 Syntaxin-like protein TMF_DNA_bd PF12329.8 CBY10820.1 - 0.0051 16.8 6.8 0.0079 16.2 6.8 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding PTRF_SDPR PF15237.6 CBY10820.1 - 0.0078 15.9 0.4 0.0086 15.7 0.4 1.1 1 0 0 1 1 1 1 PTRF/SDPR family PKcGMP_CC PF16808.5 CBY10820.1 - 0.0099 15.7 2.6 0.0099 15.7 2.6 2.6 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF16 PF01519.16 CBY10820.1 - 0.022 15.2 0.8 0.028 14.9 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF641 PF04859.12 CBY10820.1 - 0.028 14.7 0.6 0.041 14.2 0.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) FlxA PF14282.6 CBY10820.1 - 0.033 14.2 0.3 0.041 13.9 0.3 1.1 1 0 0 1 1 1 0 FlxA-like protein LXG PF04740.12 CBY10820.1 - 0.034 13.9 0.2 0.045 13.5 0.2 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF536 PF04394.14 CBY10820.1 - 0.046 13.6 3.9 2 8.3 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF536 SseC PF04888.12 CBY10820.1 - 0.058 13.0 0.1 0.061 12.9 0.1 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family PELOTA_1 PF15608.6 CBY10820.1 - 0.062 13.2 0.0 0.072 13.0 0.0 1.4 1 1 0 1 1 1 0 PELOTA RNA binding domain Fungal_TACC PF12709.7 CBY10820.1 - 0.11 12.9 3.3 0.19 12.2 3.3 1.3 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Prefoldin_2 PF01920.20 CBY10820.1 - 0.21 11.6 5.0 0.31 11.0 5.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit EF-hand_7 PF13499.6 CBY10821.1 - 1.5e-11 44.6 7.8 4.4e-09 36.7 1.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY10821.1 - 7.5e-10 37.7 1.4 0.00029 20.2 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY10821.1 - 4.3e-09 35.6 1.3 0.0017 18.1 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY10821.1 - 6.7e-07 28.5 0.4 0.0056 16.1 0.0 3.2 2 0 0 2 2 2 2 EF hand DUF3659 PF12396.8 CBY10821.1 - 0.016 15.1 16.7 0.39 10.7 1.3 4.8 1 1 4 5 5 5 0 Protein of unknown function (DUF3659) EF-hand_8 PF13833.6 CBY10821.1 - 0.14 12.0 1.1 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Toprim PF01751.22 CBY10821.1 - 0.16 12.2 0.0 6.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Toprim domain Lipoprotein_15 PF03640.15 CBY10821.1 - 0.84 9.2 3.6 81 2.9 0.0 4.4 6 0 0 6 6 6 0 Secreted repeat of unknown function INPP5B_PH PF16776.5 CBY10822.1 - 0.036 13.8 0.0 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain BCD PF15461.6 CBY10823.1 - 0.00041 19.9 1.0 0.00063 19.3 0.9 1.4 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase PIG-Y PF15159.6 CBY10823.1 - 1.9 9.4 7.8 0.35 11.8 3.5 1.9 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PG_binding_1 PF01471.18 CBY10824.1 - 2.4e-05 24.5 0.1 1.6 9.0 0.0 3.9 4 0 0 4 4 4 2 Putative peptidoglycan binding domain Ribosomal_S18 PF01084.20 CBY10824.1 - 0.0018 18.5 0.0 0.15 12.3 0.0 3.1 2 0 0 2 2 2 1 Ribosomal protein S18 PG_binding_2 PF08823.11 CBY10824.1 - 0.0066 16.7 0.0 43 4.5 0.0 4.2 3 1 1 4 4 4 1 Putative peptidoglycan binding domain RNA_pol_Rpb1_1 PF04997.12 CBY10825.1 - 4.6e-36 124.7 0.0 5.7e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Pkinase PF00069.25 CBY10826.1 - 5.5e-10 39.1 0.8 1.2e-09 38.0 0.8 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10826.1 - 3.6e-05 23.2 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Rib_recp_KP_reg PF05104.12 CBY10827.1 - 0.14 13.2 4.8 0.18 12.8 4.8 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region HCV_NS5a_C PF12941.7 CBY10827.1 - 0.27 11.0 3.9 0.47 10.3 4.0 1.3 1 1 0 1 1 1 0 HCV NS5a protein C-terminal region zf-RING_2 PF13639.6 CBY10828.1 - 5.3e-08 33.1 12.5 1.3e-07 31.8 12.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY10828.1 - 1.3e-06 28.1 10.4 3e-06 27.0 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY10828.1 - 1.7e-05 24.6 12.7 4.1e-05 23.5 12.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY10828.1 - 4.4e-05 23.3 13.6 0.00012 21.9 13.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY10828.1 - 6.5e-05 22.9 5.3 0.0023 17.9 6.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY10828.1 - 0.00014 21.6 12.2 0.00029 20.6 12.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2120 PF09893.9 CBY10828.1 - 0.00078 19.6 0.3 0.38 10.8 0.1 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2120) DASH_Dam1 PF08653.10 CBY10828.1 - 0.0029 17.4 2.1 0.47 10.3 0.1 2.2 2 0 0 2 2 2 2 DASH complex subunit Dam1 Prok-RING_4 PF14447.6 CBY10828.1 - 0.003 17.4 10.4 0.031 14.1 9.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY10828.1 - 0.0033 17.2 11.2 0.0088 15.8 11.2 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain YflT PF11181.8 CBY10828.1 - 0.004 17.6 0.3 0.098 13.2 0.1 2.1 1 1 1 2 2 2 1 Heat induced stress protein YflT TipAS PF07739.13 CBY10828.1 - 0.0046 17.5 0.0 0.007 16.9 0.0 1.3 1 0 0 1 1 1 1 TipAS antibiotic-recognition domain MobL PF18555.1 CBY10828.1 - 0.0073 15.6 1.0 0.59 9.3 0.2 2.0 1 1 1 2 2 2 1 MobL relaxases DUF2256 PF10013.9 CBY10828.1 - 0.032 14.4 4.4 0.046 13.9 0.3 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_IE-1 PF05290.11 CBY10828.1 - 0.073 13.0 14.0 0.015 15.2 10.2 1.8 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) TraI_2_C PF07515.11 CBY10828.1 - 0.084 12.8 0.1 0.14 12.1 0.1 1.7 1 1 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term DUF4208 PF13907.6 CBY10828.1 - 0.086 13.3 0.6 0.61 10.5 0.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) Cnl2_NKP2 PF09447.10 CBY10828.1 - 0.15 12.2 2.8 28 5.0 0.1 3.3 1 1 2 3 3 3 0 Cnl2/NKP2 family protein zf-RING_11 PF17123.5 CBY10828.1 - 0.23 11.2 9.6 0.11 12.3 5.7 2.4 2 0 0 2 2 2 0 RING-like zinc finger ACP_PD PF04336.12 CBY10828.1 - 0.33 11.4 1.2 6.2 7.3 0.1 2.6 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase zf-C3HC4_4 PF15227.6 CBY10828.1 - 0.67 10.2 10.1 13 6.0 10.7 2.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 CBY10828.1 - 0.94 8.8 10.9 1.2 8.5 9.5 1.9 1 1 1 2 2 2 0 Rtf2 RING-finger Pkinase_Tyr PF07714.17 CBY10830.1 - 3.1e-41 141.4 0.0 9.5e-38 129.9 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBY10830.1 - 8.9e-28 97.4 0.8 1.8e-24 86.5 0.0 3.0 2 1 0 3 3 3 2 Protein kinase domain Kdo PF06293.14 CBY10830.1 - 0.0057 16.0 0.0 0.009 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY10830.1 - 0.048 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase MFS_1 PF07690.16 CBY10831.1 - 4.9e-18 65.2 13.2 5.3e-18 65.1 13.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBY10831.1 - 1e-07 30.7 3.2 1.1e-07 30.6 2.7 1.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF4567 PF15131.6 CBY10831.1 - 0.084 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) FeoB_C PF07664.12 CBY10831.1 - 9.4 6.0 8.4 7.7 6.3 0.8 3.4 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus VWD PF00094.25 CBY10832.1 - 7.7e-26 91.3 9.5 9e-17 61.8 0.7 3.7 3 0 0 3 3 3 3 von Willebrand factor type D domain TIL PF01826.17 CBY10832.1 - 1.9e-07 31.2 34.3 3.4e-06 27.2 13.7 5.9 5 0 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain Sulfotransfer_1 PF00685.27 CBY10836.1 - 0.011 15.2 0.5 0.016 14.7 0.5 1.4 1 1 0 1 1 1 0 Sulfotransferase domain VWA PF00092.28 CBY10837.1 - 3.4e-31 108.8 2.1 7.2e-31 107.8 2.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY10837.1 - 4.8e-12 46.5 1.7 7.1e-12 45.9 0.4 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain CUB PF00431.20 CBY10837.1 - 1.7e-06 28.4 0.3 1.9e-05 24.9 0.1 2.7 2 1 0 2 2 2 1 CUB domain VWA_3 PF13768.6 CBY10837.1 - 3.6e-05 23.8 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain EB PF01683.18 CBY10837.1 - 0.45 10.9 20.1 1.7 9.0 5.0 2.7 1 1 1 2 2 2 0 EB module Kelch_5 PF13854.6 CBY10838.1 - 2.3e-05 24.3 1.6 0.079 13.0 0.1 3.3 3 0 0 3 3 3 2 Kelch motif CUB PF00431.20 CBY10839.1 - 2.1e-11 44.1 0.8 2.7e-11 43.8 0.8 1.1 1 0 0 1 1 1 1 CUB domain PknG_rubred PF16919.5 CBY10840.1 - 0.023 14.8 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain WAP PF00095.21 CBY10840.1 - 0.13 12.7 1.0 0.13 12.7 1.0 2.0 2 1 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' MDM10 PF12519.8 CBY10840.1 - 0.18 10.6 0.9 0.98 8.2 0.9 1.8 1 1 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Sulfotransfer_2 PF03567.14 CBY10841.1 - 2e-22 80.3 0.1 3e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family MFS_1 PF07690.16 CBY10842.1 - 3.1e-31 108.6 32.7 3.5e-20 72.2 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CBY10842.1 - 3.6e-05 23.2 13.7 0.0035 16.7 1.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Gram_pos_anchor PF00746.21 CBY10842.1 - 0.33 10.9 3.3 0.59 10.1 0.1 2.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif I-set PF07679.16 CBY10843.1 - 4.8e-19 68.2 0.1 1.1e-16 60.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY10843.1 - 1.1e-16 60.9 0.1 1.1e-12 48.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 CBY10843.1 - 3.2e-16 59.7 0.0 6.4e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CBY10843.1 - 4.6e-09 36.3 0.0 3.7e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 CBY10843.1 - 2.5e-05 24.3 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 CBY10843.1 - 0.00096 19.5 0.0 0.0097 16.3 0.0 2.1 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 CBY10843.1 - 0.006 16.7 0.1 2.2 8.5 0.0 2.8 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 CBY10843.1 - 0.017 15.2 0.1 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 C17orf99 Ig domain Ig_6 PF18452.1 CBY10843.1 - 0.037 13.6 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Phospholip_A2_1 PF00068.19 CBY10844.1 - 1.6e-16 60.7 11.4 2.9e-16 59.9 11.4 1.4 1 0 0 1 1 1 1 Phospholipase A2 FPP PF05911.11 CBY10845.1 - 0.39 8.9 67.4 0.014 13.6 49.2 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DivIC PF04977.15 CBY10845.1 - 1 9.2 0.0 1 9.2 0.0 7.7 2 1 6 8 8 8 0 Septum formation initiator Fez1 PF06818.15 CBY10845.1 - 3.5 8.0 57.2 0.33 11.4 34.2 2.6 1 1 2 3 3 3 0 Fez1 GAS2 PF02187.17 CBY10846.1 - 2.5e-19 69.1 0.1 4.2e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 CBY10846.1 - 4.3e-10 39.8 0.0 6.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain EF-hand_1 PF00036.32 CBY10847.1 - 4.4e-10 38.4 0.1 1.8e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY10847.1 - 3.4e-08 32.8 0.1 0.00017 21.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBY10847.1 - 4.8e-08 33.3 0.0 7.4e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY10847.1 - 8e-08 31.4 2.9 1.1e-06 27.8 0.3 2.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CBY10847.1 - 2e-05 24.3 0.2 0.00083 19.2 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY10847.1 - 0.17 12.2 0.0 0.21 11.9 0.0 1.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region LpxD PF04613.14 CBY10847.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Pkinase PF00069.25 CBY10848.1 - 5.5e-11 42.3 0.0 2.5e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10848.1 - 3.3e-07 29.8 0.0 2.4e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3458 PF11940.8 CBY10848.1 - 0.028 14.9 0.2 8.8 6.8 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3458) Ig-like fold GatB_Yqey PF02637.18 CBY10848.1 - 0.3 10.9 2.0 39 4.1 0.3 3.4 3 0 0 3 3 3 0 GatB domain AbrB_C PF18277.1 CBY10849.1 - 0.031 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 AbrB C-terminal domain VWA PF00092.28 CBY10850.1 - 2.3e-156 516.5 19.2 1.1e-33 116.9 0.8 5.1 5 0 0 5 5 5 5 von Willebrand factor type A domain VWA_2 PF13519.6 CBY10850.1 - 5.3e-69 229.7 3.4 2.6e-16 60.2 0.0 5.3 5 0 0 5 5 5 5 von Willebrand factor type A domain VWA_3 PF13768.6 CBY10850.1 - 2e-24 86.3 0.1 1e-05 25.5 0.0 5.1 5 0 0 5 5 5 4 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY10850.1 - 7.6e-16 58.2 2.5 0.00032 20.2 0.0 5.8 6 0 0 6 6 6 4 VWA domain containing CoxE-like protein DUF1194 PF06707.11 CBY10850.1 - 1.4e-14 53.8 6.9 0.0056 15.9 0.5 5.8 5 1 0 5 5 5 4 Protein of unknown function (DUF1194) vWA-TerF-like PF10138.9 CBY10850.1 - 9.9e-14 51.9 5.2 0.0005 20.2 0.0 4.8 5 1 0 5 5 5 4 vWA found in TerF C terminus Copine PF07002.16 CBY10850.1 - 1e-06 28.4 0.1 0.64 9.4 0.1 4.3 4 0 0 4 4 4 2 Copine DUF2201 PF09967.9 CBY10850.1 - 4.2e-05 23.7 1.2 5.1 7.3 0.0 4.5 4 0 0 4 4 4 2 VWA-like domain (DUF2201) CobT_C PF11775.8 CBY10850.1 - 6.1e-05 22.8 0.1 8.8 5.9 0.0 4.8 4 0 0 4 4 4 2 Cobalamin biosynthesis protein CobT VWA domain GGDEF_2 PF17853.1 CBY10850.1 - 0.0088 16.3 0.2 12 6.2 0.0 4.0 4 0 0 4 4 4 1 GGDEF-like domain Ssl1 PF04056.14 CBY10850.1 - 0.034 14.0 0.0 0.46 10.3 0.0 2.6 3 0 0 3 3 3 0 Ssl1-like YjeF_N PF03853.15 CBY10850.1 - 0.058 13.3 0.0 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 YjeF-related protein N-terminus AhpC-TSA_2 PF13911.6 CBY10850.1 - 0.17 12.0 3.0 39 4.4 0.0 4.9 6 0 0 6 6 6 0 AhpC/TSA antioxidant enzyme Glyco_tran_WecB PF03808.13 CBY10850.1 - 0.24 11.3 0.3 31 4.5 0.0 3.9 5 0 0 5 5 5 0 Glycosyl transferase WecB/TagA/CpsF family DUF3524 PF12038.8 CBY10851.1 - 3.3e-60 202.7 0.2 7.5e-60 201.6 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 CBY10851.1 - 6e-08 32.4 0.0 1.5e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Gla PF00594.20 CBY10851.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain CUB PF00431.20 CBY10852.1 - 3.3e-13 49.9 0.5 2.1e-10 40.9 0.1 2.7 1 1 1 2 2 2 2 CUB domain IMUP PF15761.5 CBY10852.1 - 0.017 15.8 4.4 0.033 14.9 4.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Lectin_C PF00059.21 CBY10853.1 - 3.7e-16 59.8 0.9 6.5e-16 59.0 0.9 1.4 1 0 0 1 1 1 1 Lectin C-type domain Somatomedin_B PF01033.17 CBY10853.1 - 9.6e-06 25.9 10.8 9.6e-06 25.9 10.8 3.0 3 1 0 3 3 3 1 Somatomedin B domain Kringle PF00051.18 CBY10859.1 - 6.3e-70 231.5 30.8 3.9e-25 88.0 5.1 3.8 3 0 0 3 3 3 3 Kringle domain FXa_inhibition PF14670.6 CBY10859.1 - 0.0091 16.3 12.4 0.0091 16.3 12.4 3.2 2 1 0 2 2 2 1 Coagulation Factor Xa inhibitory site DUF3719 PF12516.8 CBY10859.1 - 0.11 12.2 0.2 8.9 6.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3719) Toxin_5 PF05294.13 CBY10859.1 - 2.2 8.7 20.8 5 7.6 0.2 5.1 4 1 1 5 5 5 0 Scorpion short toxin Pkinase_Tyr PF07714.17 CBY10860.1 - 1e-09 38.1 0.0 3.4e-09 36.4 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CBY10860.1 - 1.2e-09 38.0 0.1 3.2e-09 36.5 0.1 1.6 1 1 1 2 2 2 1 Protein kinase domain VPR PF00522.18 CBY10860.1 - 0.028 14.5 1.3 9.8 6.3 0.1 2.7 2 0 0 2 2 2 0 VPR/VPX protein TIP39 PF14980.6 CBY10860.1 - 0.049 13.5 0.2 15 5.5 0.0 2.6 2 0 0 2 2 2 0 TIP39 peptide GLTSCR1 PF15249.6 CBY10860.1 - 0.057 13.9 0.8 2.5 8.6 0.1 2.7 2 1 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein TetR_C_28 PF17937.1 CBY10860.1 - 0.082 13.4 0.0 14 6.2 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain F420_ligase PF01996.16 CBY10862.1 - 0.2 11.0 3.1 0.42 9.9 1.9 2.0 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase RVT_1 PF00078.27 CBY10863.1 - 4.5e-32 111.3 0.0 9.5e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S9 PF00326.21 CBY10864.1 - 2.5e-10 40.2 0.5 0.0021 17.5 0.0 3.1 1 1 2 3 3 3 3 Prolyl oligopeptidase family Kelch_6 PF13964.6 CBY10865.1 - 0.0094 16.2 10.4 13 6.2 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Glyco_transf_10 PF00852.19 CBY10866.1 - 4.6e-24 85.1 0.0 9.3e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Pkinase PF00069.25 CBY10866.1 - 6.5e-11 42.1 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10866.1 - 2.3e-08 33.7 0.0 3.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_tran_10_N PF17039.5 CBY10866.1 - 0.00047 20.6 0.4 0.0012 19.2 0.4 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Leader_CPA1 PF08252.11 CBY10866.1 - 0.05 13.0 0.1 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide SAA PF00277.18 CBY10867.1 - 0.024 15.1 0.0 0.69 10.4 0.0 2.0 1 1 1 2 2 2 0 Serum amyloid A protein PI3K_P85_iSH2 PF16454.5 CBY10867.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Amidase PF01425.21 CBY10868.1 - 3.5e-18 65.8 0.0 1.7e-17 63.5 0.0 1.8 1 1 0 1 1 1 1 Amidase Lectin_C PF00059.21 CBY10869.1 - 2.4e-12 47.6 3.6 2.8e-12 47.3 3.6 1.0 1 0 0 1 1 1 1 Lectin C-type domain IL3Ra_N PF18611.1 CBY10869.1 - 0.35 10.9 4.6 0.48 10.5 4.6 1.3 1 0 0 1 1 1 0 IL-3 receptor alpha chain N-terminal domain Cation_efflux PF01545.21 CBY10870.1 - 3.8e-09 36.6 2.4 8.4e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Cation efflux family Amidase PF01425.21 CBY10871.1 - 1.6e-53 182.3 0.4 2.1e-53 181.9 0.4 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 CBY10872.1 - 1.1e-16 60.8 0.0 6.1e-16 58.4 0.0 1.8 1 1 0 1 1 1 1 Amidase Lectin_C PF00059.21 CBY10873.1 - 4.2e-11 43.5 0.2 1e-10 42.3 0.2 1.6 1 0 0 1 1 1 1 Lectin C-type domain Amidase PF01425.21 CBY10875.1 - 1.1e-67 229.0 0.0 1.3e-67 228.8 0.0 1.0 1 0 0 1 1 1 1 Amidase PMP22_Claudin PF00822.20 CBY10876.1 - 3.1e-10 40.2 12.5 3.2e-08 33.6 12.5 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family T_cell_tran_alt PF15128.6 CBY10876.1 - 0.085 12.7 0.2 0.94 9.3 0.0 2.2 1 1 1 2 2 2 0 T-cell leukemia translocation-altered Pkinase PF00069.25 CBY10877.1 - 5.4e-22 78.4 0.3 9.4e-22 77.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10877.1 - 2.9e-05 23.5 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_integrase PF00589.22 CBY10878.1 - 0.002 18.0 0.7 0.0045 16.8 0.0 1.8 1 1 1 2 2 2 1 Phage integrase family DUF3012 PF11216.8 CBY10879.1 - 0.0098 15.9 0.4 0.03 14.3 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3012) SCVP PF17619.2 CBY10879.1 - 0.024 15.5 0.4 0.047 14.5 0.4 1.5 1 0 0 1 1 1 0 Secreted clade V proteins PH_14 PF17787.1 CBY10879.1 - 0.025 14.4 0.3 0.042 13.7 0.3 1.3 1 0 0 1 1 1 0 PH domain DUF155 PF02582.14 CBY10881.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 DUF563 PF04577.14 CBY10881.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF563) DisA_N PF02457.16 CBY10881.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding zinc_ribbon_4 PF13717.6 CBY10886.1 - 0.24 11.3 0.9 4.7 7.2 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain ORMDL PF04061.14 CBY10888.1 - 0.18 11.6 0.1 0.72 9.7 0.1 1.9 2 0 0 2 2 2 0 ORMDL family HEPN_DZIP3 PF18738.1 CBY10888.1 - 2.3 7.9 6.6 0.86 9.3 2.0 2.2 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN Pan3_PK PF18101.1 CBY10889.1 - 0.0031 17.5 0.1 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 Pan3 Pseudokinase domain Mt_ATP-synt_B PF05405.14 CBY10889.1 - 0.0088 15.7 1.7 0.021 14.5 1.7 1.6 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Alpha-mann_mid PF09261.11 CBY10889.1 - 0.045 13.9 0.0 0.24 11.6 0.0 2.3 1 0 0 1 1 1 0 Alpha mannosidase middle domain Phage_integrase PF00589.22 CBY10889.1 - 0.093 12.5 1.9 0.64 9.8 0.1 3.3 2 2 2 4 4 4 0 Phage integrase family TnpV PF14198.6 CBY10889.1 - 0.7 9.9 5.1 0.43 10.6 1.9 2.3 2 0 0 2 2 2 0 Transposon-encoded protein TnpV ABC_tran_CTD PF16326.5 CBY10890.1 - 0.027 14.7 4.5 0.21 11.8 1.7 3.3 3 1 0 3 3 3 0 ABC transporter C-terminal domain SusF_SusE PF16411.5 CBY10890.1 - 0.13 12.8 1.2 0.22 12.0 0.2 1.8 2 0 0 2 2 2 0 Outer membrane protein SusF_SusE Seryl_tRNA_N PF02403.22 CBY10890.1 - 0.14 12.4 3.7 0.14 12.4 1.8 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MtrG PF04210.13 CBY10890.1 - 0.19 11.6 0.4 17 5.4 0.2 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4055 PF13264.6 CBY10890.1 - 0.39 10.9 2.4 2.6 8.2 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4055) TPR_MLP1_2 PF07926.12 CBY10890.1 - 1.1 9.3 11.5 0.034 14.2 2.6 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2046 PF09755.9 CBY10892.1 - 0.013 14.7 0.4 0.039 13.2 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF5082 PF16888.5 CBY10892.1 - 3.5 7.9 7.6 1.6 9.0 0.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) rve PF00665.26 CBY10893.1 - 4.9e-14 52.5 0.0 8.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY10893.1 - 1.9e-07 31.1 0.6 4.9e-07 29.8 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain bZIP_1 PF00170.21 CBY10894.1 - 5.2e-09 36.1 9.4 1e-08 35.1 9.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY10894.1 - 1.2e-08 34.9 8.8 3e-08 33.6 8.8 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY10894.1 - 0.00072 20.0 8.7 0.00072 20.0 8.7 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF799 PF05643.11 CBY10894.1 - 0.066 12.8 0.3 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) Phospholip_A2_1 PF00068.19 CBY10895.1 - 2.7e-11 43.9 10.1 2.7e-11 43.9 10.1 2.1 2 0 0 2 2 2 1 Phospholipase A2 Neur_chan_memb PF02932.16 CBY10896.1 - 9.1e-05 22.6 0.7 0.00013 22.1 0.7 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2748 PF10871.8 CBY10896.1 - 0.12 10.9 2.0 0.16 10.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) DUF5337 PF17272.2 CBY10896.1 - 0.16 11.8 0.1 0.42 10.5 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Pkinase_fungal PF17667.1 CBY10897.1 - 0.14 10.9 0.8 0.2 10.4 0.8 1.1 1 0 0 1 1 1 0 Fungal protein kinase SSF PF00474.17 CBY10898.1 - 7.8e-36 123.8 32.8 1e-35 123.4 32.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family GATase PF00117.28 CBY10899.1 - 8.9e-18 64.7 0.0 2.4e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 CBY10899.1 - 4.6e-15 55.5 0.0 3.5e-09 36.6 0.0 3.1 3 0 0 3 3 3 2 GMP synthase C terminal domain NAD_synthase PF02540.17 CBY10899.1 - 1.9e-09 37.0 0.0 9.1e-06 25.0 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CBY10899.1 - 3.2e-07 30.3 0.0 7.7e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.13 CBY10899.1 - 0.00047 19.7 0.0 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 CBY10899.1 - 0.0052 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 CBY10899.1 - 0.034 12.9 0.1 0.24 10.1 0.0 2.0 2 0 0 2 2 2 0 tRNA methyl transferase PAPS_reduct PF01507.19 CBY10899.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Phage_holin_8 PF16931.5 CBY10901.1 - 0.036 14.0 0.4 0.73 9.8 0.1 2.5 2 0 0 2 2 2 0 Putative phage holin Phtf-FEM1B_bdg PF12129.8 CBY10902.1 - 5.1e-24 84.8 0.0 7e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor NKAIN PF05640.14 CBY10902.1 - 0.14 11.4 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein ubiquitin PF00240.23 CBY10903.1 - 2.6e-08 33.5 0.1 4.1e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CBY10903.1 - 0.0002 21.4 0.0 0.0005 20.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4607 PF15380.6 CBY10903.1 - 0.023 14.2 0.7 0.032 13.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) DUF2407 PF10302.9 CBY10903.1 - 0.036 14.6 1.4 0.044 14.3 0.3 1.8 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain MFAP1 PF06991.11 CBY10903.1 - 0.038 13.8 1.3 0.075 12.9 1.3 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Prefoldin_2 PF01920.20 CBY10904.1 - 8.6e-13 48.2 5.7 8.6e-13 48.2 5.7 2.0 1 1 1 2 2 2 1 Prefoldin subunit FTA4 PF13093.6 CBY10904.1 - 0.00024 21.0 0.9 0.00024 21.0 0.9 1.6 1 1 1 2 2 2 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HOOK PF05622.12 CBY10904.1 - 0.0031 15.7 7.8 0.0038 15.5 7.8 1.1 1 0 0 1 1 1 1 HOOK protein DUF1664 PF07889.12 CBY10904.1 - 0.0056 16.7 10.3 0.17 11.9 1.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBY10904.1 - 0.0063 15.4 11.4 0.077 11.9 0.9 2.0 2 0 0 2 2 2 2 Spc7 kinetochore protein Herpes_UL6 PF01763.16 CBY10904.1 - 0.0087 14.6 5.4 0.0088 14.6 3.7 1.7 1 1 1 2 2 2 1 Herpesvirus UL6 like Pox_A_type_inc PF04508.12 CBY10904.1 - 0.0095 15.7 0.2 0.037 13.9 0.0 2.2 2 0 0 2 2 1 1 Viral A-type inclusion protein repeat DUF4200 PF13863.6 CBY10904.1 - 0.015 15.7 11.0 0.02 15.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Sas6_CC PF18594.1 CBY10904.1 - 0.019 14.7 1.4 0.019 14.7 1.4 2.5 4 0 0 4 4 2 0 Sas6/XLF/XRCC4 coiled-coil domain T4_Rnl2_C PF18043.1 CBY10904.1 - 0.028 14.6 3.8 0.47 10.6 1.3 2.3 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal Tup_N PF08581.10 CBY10904.1 - 0.041 14.2 5.7 1 9.7 0.4 2.3 2 0 0 2 2 2 0 Tup N-terminal DUF1451 PF07295.11 CBY10904.1 - 0.073 13.1 2.8 0.11 12.5 0.4 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain TRAF_BIRC3_bd PF16673.5 CBY10904.1 - 0.08 12.8 6.2 0.35 10.7 1.0 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF4446 PF14584.6 CBY10904.1 - 0.093 12.7 4.7 0.34 10.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 CBY10904.1 - 0.1 11.8 9.2 0.33 10.1 2.4 2.0 1 1 0 2 2 2 0 TMPIT-like protein DUF5082 PF16888.5 CBY10904.1 - 0.1 12.8 7.0 0.58 10.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Tropomyosin_1 PF12718.7 CBY10904.1 - 0.1 12.7 9.0 0.38 10.9 0.3 2.2 2 0 0 2 2 2 0 Tropomyosin like BLOC1_2 PF10046.9 CBY10904.1 - 0.11 12.8 7.3 0.25 11.7 0.4 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 CBY10904.1 - 0.13 12.3 7.1 0.061 13.3 2.8 2.1 1 1 1 2 2 2 0 Laminin Domain II Sec8_exocyst PF04048.14 CBY10904.1 - 0.17 11.8 7.4 1.1 9.2 1.4 2.6 2 2 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF3450 PF11932.8 CBY10904.1 - 0.2 10.9 9.2 0.54 9.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 CBY10904.1 - 0.2 11.7 8.9 0.43 10.7 3.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DegS PF05384.11 CBY10904.1 - 0.21 11.1 9.0 0.63 9.5 2.5 2.0 2 0 0 2 2 2 0 Sensor protein DegS Occludin_ELL PF07303.13 CBY10904.1 - 0.27 12.0 8.4 5.8 7.7 0.3 2.8 1 1 2 3 3 3 0 Occludin homology domain LPD5 PF18799.1 CBY10904.1 - 0.27 11.6 3.6 1.1 9.7 0.1 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 RasGAP_C PF03836.15 CBY10904.1 - 0.29 11.3 5.5 1.3 9.2 1.2 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Seryl_tRNA_N PF02403.22 CBY10904.1 - 0.29 11.4 12.5 2.1 8.6 0.7 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4201 PF13870.6 CBY10904.1 - 0.32 10.7 10.0 1.4 8.6 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ING PF12998.7 CBY10904.1 - 0.33 11.6 6.0 1.8 9.2 6.0 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Atg14 PF10186.9 CBY10904.1 - 0.42 9.7 6.4 0.85 8.6 6.4 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TBCA PF02970.16 CBY10904.1 - 0.51 10.7 8.1 2.5 8.5 1.1 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A ATG16 PF08614.11 CBY10904.1 - 0.58 10.3 9.0 0.97 9.6 0.4 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CBY10904.1 - 0.74 10.3 11.6 0.57 10.7 1.1 2.1 1 1 0 2 2 2 0 Apg6 coiled-coil region eIF3_N PF09440.10 CBY10904.1 - 1.3 9.5 7.6 1.9 8.9 0.7 2.2 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Fzo_mitofusin PF04799.13 CBY10904.1 - 1.6 8.2 10.3 3.9 7.0 0.8 2.1 2 0 0 2 2 2 0 fzo-like conserved region VASP_tetra PF08776.11 CBY10904.1 - 2 8.0 11.0 3.1 7.4 1.6 3.2 2 2 0 2 2 2 0 VASP tetramerisation domain KxDL PF10241.9 CBY10904.1 - 2.5 8.4 9.0 6.9 7.0 3.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein PBP1_TM PF14812.6 CBY10905.1 - 3 8.3 6.3 0.61 10.5 0.8 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_4 PF13894.6 CBY10906.1 - 1.7e-07 31.5 32.4 0.008 16.9 2.7 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY10906.1 - 5.8e-05 22.7 19.3 0.041 13.6 1.2 6.2 5 1 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CBY10906.1 - 0.00021 21.5 13.4 0.017 15.4 0.9 5.0 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY10906.1 - 0.00027 21.2 26.2 0.06 13.8 0.1 6.0 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY10906.1 - 0.0016 18.8 33.5 0.039 14.4 1.2 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type TraY PF05509.11 CBY10906.1 - 0.0059 16.6 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 TraY domain ZirS_C PF16583.5 CBY10906.1 - 0.019 14.5 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain zf-met PF12874.7 CBY10906.1 - 0.4 11.2 12.9 0.49 10.8 0.9 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Bax1-I PF01027.20 CBY10907.1 - 1.3e-36 126.4 16.1 1.5e-36 126.2 16.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CBY10907.1 - 0.097 12.2 9.1 0.13 11.8 9.1 1.1 1 0 0 1 1 1 0 Bax inhibitor 1 like 7TMR-DISM_7TM PF07695.11 CBY10907.1 - 0.55 10.1 13.0 6.1 6.7 8.1 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2244 PF10003.9 CBY10907.1 - 5.7 6.6 6.4 1 9.0 0.1 2.4 1 1 0 2 2 2 0 Integral membrane protein (DUF2244) zf-H2C2_5 PF13909.6 CBY10908.1 - 3.1e-14 52.4 24.6 7.5e-05 22.4 0.2 6.3 6 1 0 6 6 6 4 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBY10908.1 - 5.9e-10 39.1 33.1 0.00053 20.6 0.2 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY10908.1 - 7.6e-10 38.7 29.1 0.00014 22.1 0.3 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY10908.1 - 6.4e-07 29.5 29.2 0.069 13.6 0.1 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY10908.1 - 1.2e-05 25.4 19.7 0.0037 17.5 0.5 5.6 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding DUF3458 PF11940.8 CBY10908.1 - 0.0052 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Aldo_ket_red PF00248.21 CBY10908.1 - 0.0077 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2256 PF10013.9 CBY10908.1 - 0.087 13.0 5.1 2.5 8.3 0.0 3.4 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2256) OrsD PF12013.8 CBY10908.1 - 0.098 13.1 0.1 0.098 13.1 0.1 4.4 3 2 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D Rota_VP4_MID PF17477.2 CBY10908.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain zf-C2H2_2 PF12756.7 CBY10908.1 - 0.13 12.6 21.2 2.1 8.7 11.0 4.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CBY10908.1 - 0.52 10.4 0.1 0.52 10.4 0.1 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 CBY10908.1 - 2.7 8.5 0.0 2.7 8.5 0.0 4.6 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DNA_RNApol_7kD PF03604.13 CBY10908.1 - 7.7 6.3 10.4 9.5 6.0 0.1 3.5 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit SAC3_GANP PF03399.16 CBY10909.1 - 5.5e-26 91.6 3.2 1.7e-24 86.7 3.2 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CBY10909.1 - 6.1e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RPN7 PF10602.9 CBY10909.1 - 0.00075 19.3 0.8 0.0015 18.3 0.8 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 dCMP_cyt_deam_2 PF08211.12 CBY10909.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region PHD PF00628.29 CBY10910.1 - 0.00072 19.4 5.2 0.0013 18.6 5.2 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 CBY10910.1 - 0.032 14.1 0.7 0.064 13.2 0.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CBY10910.1 - 0.49 10.5 4.3 1.1 9.4 4.3 1.6 1 0 0 1 1 1 0 PHD-finger DLIC PF05783.11 CBY10911.1 - 8.8e-29 100.6 0.4 1.9e-25 89.7 0.1 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 CBY10911.1 - 0.01 16.1 0.0 0.026 14.7 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY10911.1 - 0.029 14.0 0.2 0.28 10.8 0.1 2.4 1 1 1 2 2 2 0 Ras family ABC_tran PF00005.27 CBY10911.1 - 0.063 13.8 0.0 0.17 12.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DLIC PF05783.11 CBY10912.1 - 1.7e-62 211.9 0.0 1.9e-35 122.6 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 CBY10912.1 - 0.033 14.4 0.0 0.083 13.1 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY10912.1 - 0.045 13.4 0.1 0.75 9.4 0.1 2.6 1 1 0 1 1 1 0 Ras family ABC_tran PF00005.27 CBY10912.1 - 0.077 13.5 0.1 0.54 10.8 0.0 2.3 2 1 0 2 2 2 0 ABC transporter IF-2B PF01008.17 CBY10913.1 - 3e-39 134.9 0.8 5.1e-39 134.2 0.8 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family GMP_synt_C PF00958.22 CBY10914.1 - 1.9e-11 43.8 0.0 4.2e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 GMP synthase C terminal domain PQ-loop PF04193.14 CBY10915.1 - 2.2e-36 123.4 4.7 8.3e-19 67.1 2.4 2.8 2 0 0 2 2 2 2 PQ loop repeat Fibrinogen_C PF00147.18 CBY10916.1 - 5.7e-05 23.0 0.1 0.00011 22.1 0.1 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 CBY10916.1 - 0.0032 17.4 3.6 0.077 12.9 0.3 2.2 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF4803 PF16061.5 CBY10916.1 - 0.0057 16.1 0.3 0.0057 16.1 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4803) Fib_alpha PF08702.10 CBY10916.1 - 0.27 11.4 5.8 0.045 13.9 1.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 CBY10916.1 - 0.37 11.1 8.2 0.086 13.2 1.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Sec2p PF06428.11 CBY10916.1 - 0.74 9.8 4.8 0.37 10.8 2.0 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p IFT57 PF10498.9 CBY10916.1 - 1.2 8.0 7.3 4.4 6.2 7.3 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 CUB PF00431.20 CBY10919.1 - 1.3e-07 31.9 1.4 2e-07 31.3 0.9 1.6 1 1 1 2 2 2 1 CUB domain BNR PF02012.20 CBY10919.1 - 0.044 13.8 0.2 0.21 11.7 0.2 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat IF-2B PF01008.17 CBY10920.1 - 1.9e-34 119.2 0.6 7.1e-25 87.8 0.2 3.0 1 1 1 2 2 2 2 Initiation factor 2 subunit family PTS_EIIB PF00367.20 CBY10920.1 - 0.1 12.1 0.8 0.2 11.2 0.8 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB DnaJ PF00226.31 CBY10921.1 - 7e-07 29.3 0.2 0.0052 16.9 0.0 2.6 1 1 1 2 2 2 2 DnaJ domain BST2 PF16716.5 CBY10921.1 - 0.042 14.4 2.4 0.081 13.5 2.4 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 RPT PF13446.6 CBY10921.1 - 0.075 13.0 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 A repeated domain in UCH-protein OATP PF03137.20 CBY10922.1 - 1.4e-28 99.6 0.6 1.9e-28 99.1 0.6 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family OATP PF03137.20 CBY10923.1 - 2e-87 293.8 8.8 2.6e-87 293.4 8.8 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.15 CBY10923.1 - 1.9e-06 27.9 1.8 4.7e-06 26.6 1.8 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Luteo_PO PF04662.13 CBY10923.1 - 0.029 14.0 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Luteovirus P0 protein Kazal_1 PF00050.21 CBY10923.1 - 0.13 12.3 2.5 0.27 11.3 2.5 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Ank_5 PF13857.6 CBY10924.1 - 0.00021 21.5 0.1 0.00037 20.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY10924.1 - 0.0082 16.7 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Pkinase PF00069.25 CBY10925.1 - 1.5e-10 40.9 2.5 2.2e-10 40.4 1.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10925.1 - 1.6e-05 24.3 0.0 3.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LTXXQ PF07813.12 CBY10927.1 - 0.08 13.7 3.1 2.5 8.9 0.2 2.5 2 0 0 2 2 2 0 LTXXQ motif family protein Atg14 PF10186.9 CBY10927.1 - 1.1 8.3 6.0 1.7 7.6 6.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Vfa1 PF08432.10 CBY10927.1 - 3.2 8.1 15.2 0.63 10.4 9.3 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GPHR_N PF12537.8 CBY10927.1 - 3.3 7.9 4.0 5.9 7.1 0.3 2.7 3 0 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal Sugar_tr PF00083.24 CBY10929.1 - 1.3e-18 67.2 0.3 1.6e-18 66.8 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY10929.1 - 2.7e-10 39.7 0.8 3.6e-10 39.3 0.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF973 PF06157.11 CBY10929.1 - 0.0059 15.7 1.7 0.0079 15.3 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) PDZ PF00595.24 CBY10929.1 - 0.021 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 CBY10929.1 - 0.056 13.3 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 PDZ domain Pkinase PF00069.25 CBY10931.1 - 1.3e-09 37.8 2.2 3.4e-09 36.5 1.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10931.1 - 0.0001 21.7 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CCT_2 PF09425.10 CBY10933.1 - 0.082 12.8 0.2 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 Divergent CCT motif Ycf9 PF01737.17 CBY10934.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 YCF9 Actin PF00022.19 CBY10935.1 - 1.7e-84 283.8 0.0 1.2e-51 175.6 0.0 2.0 1 1 1 2 2 2 2 Actin FtsA PF14450.6 CBY10935.1 - 0.00027 21.3 0.0 0.013 15.9 0.0 2.7 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 CBY10935.1 - 0.00066 18.6 0.0 0.12 11.2 0.0 2.9 2 1 0 2 2 2 2 MreB/Mbl protein RTC PF01137.21 CBY10936.1 - 3.2e-55 186.8 0.0 3.7e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase zf-C2H2 PF00096.26 CBY10937.1 - 6.6e-07 29.4 36.0 0.0032 17.8 3.1 6.5 6 1 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.7 CBY10937.1 - 0.0048 17.2 9.1 0.3 11.5 0.0 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY10937.1 - 0.007 17.1 2.9 0.007 17.1 2.9 5.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY10937.1 - 0.0091 16.3 0.6 0.24 11.7 0.3 3.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY10937.1 - 0.095 13.2 0.5 0.095 13.2 0.5 5.9 6 1 1 7 7 7 0 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 CBY10937.1 - 0.41 10.3 14.1 0.1 12.2 1.3 3.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain RAI16-like PF10257.9 CBY10938.1 - 6.4e-85 285.2 7.0 8.6e-85 284.7 7.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein ANAPC4_WD40 PF12894.7 CBY10939.1 - 4.6e-08 33.3 5.7 5.4e-05 23.4 0.4 5.0 3 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY10939.1 - 3.6e-05 24.5 0.6 0.075 13.9 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CBY10939.1 - 4e-05 22.9 4.0 0.035 13.1 0.1 2.7 2 1 1 3 3 3 3 Coatomer WD associated region eIF2A PF08662.11 CBY10939.1 - 9.2e-05 22.4 2.4 0.0012 18.8 0.1 3.0 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Vps16_N PF04841.13 CBY10939.1 - 0.00031 19.6 0.3 0.026 13.3 0.1 2.6 3 0 0 3 3 3 1 Vps16, N-terminal region HPS3_N PF14761.6 CBY10939.1 - 0.00078 19.0 0.1 0.64 9.5 0.0 3.4 4 0 0 4 4 4 2 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 CBY10939.1 - 0.003 16.9 0.3 0.56 9.5 0.1 2.7 3 0 0 3 3 3 2 WD40-like domain CNH PF00780.22 CBY10939.1 - 0.045 13.4 0.0 7.2 6.1 0.0 3.4 3 0 0 3 3 3 0 CNH domain DUF5635 PF18685.1 CBY10940.1 - 0.072 13.0 0.9 0.13 12.2 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5635) PPR PF01535.20 CBY10941.1 - 6.8e-07 29.1 4.5 0.41 11.0 0.0 6.9 6 2 1 7 7 7 2 PPR repeat Clathrin PF00637.20 CBY10941.1 - 3.9e-06 26.8 1.3 0.0097 15.8 0.0 4.8 3 1 0 4 4 4 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 CBY10941.1 - 4.5e-06 26.0 0.9 3.8e-05 22.9 0.0 2.6 3 1 0 3 3 3 1 Coatomer WD associated region TPR_7 PF13176.6 CBY10941.1 - 1.7e-05 24.5 1.7 1.1 9.4 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.6 CBY10941.1 - 0.002 17.6 1.1 0.77 9.1 0.1 2.7 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP PPR_2 PF13041.6 CBY10941.1 - 0.082 13.1 0.4 29 5.0 0.0 4.4 5 1 1 6 6 6 0 PPR repeat family TPR_2 PF07719.17 CBY10941.1 - 8.3 6.8 15.2 62 4.1 0.1 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat DEP PF00610.21 CBY10942.1 - 4.4e-17 61.9 0.1 1.7e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1539 PF07560.11 CBY10942.1 - 7.8e-05 22.8 1.0 0.027 14.6 0.1 2.7 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1539) RhoGAP PF00620.27 CBY10942.1 - 0.0074 16.1 0.4 0.023 14.5 0.2 1.9 2 0 0 2 2 2 1 RhoGAP domain FHIPEP PF00771.20 CBY10942.1 - 0.054 12.0 0.1 0.087 11.3 0.1 1.3 1 0 0 1 1 1 0 FHIPEP family IF-2B PF01008.17 CBY10943.1 - 1.3e-73 247.7 0.4 7.4e-73 245.2 0.4 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family EppA_BapA PF07268.11 CBY10943.1 - 0.14 12.1 1.3 0.29 11.1 1.3 1.4 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) IF-2B PF01008.17 CBY10944.1 - 1.1e-25 90.5 0.9 2.8e-24 85.8 0.2 2.4 2 1 0 2 2 2 1 Initiation factor 2 subunit family zf-RING_2 PF13639.6 CBY10944.1 - 1.2e-06 28.7 12.9 1.2e-06 28.7 12.9 3.5 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY10944.1 - 9e-06 25.5 11.1 9e-06 25.5 11.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY10944.1 - 0.00013 21.8 13.4 0.00013 21.8 13.4 3.6 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY10944.1 - 0.0012 18.7 14.5 0.0012 18.7 14.5 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY10944.1 - 0.0015 18.3 12.7 0.0015 18.3 12.7 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY10944.1 - 0.0046 17.0 16.7 0.0057 16.7 5.9 4.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_4 PF14570.6 CBY10944.1 - 0.015 15.1 11.6 0.015 15.1 11.6 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF4363 PF14276.6 CBY10944.1 - 0.18 11.9 1.4 14 5.9 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) PTS_EIIB PF00367.20 CBY10944.1 - 0.2 11.2 0.8 0.43 10.1 0.8 1.6 1 0 0 1 1 1 0 phosphotransferase system, EIIB Baculo_IE-1 PF05290.11 CBY10944.1 - 0.94 9.4 18.2 0.025 14.5 9.2 2.7 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) IF-2B PF01008.17 CBY10945.1 - 7.4e-26 91.0 0.2 2.5e-24 86.0 0.2 2.2 1 1 0 1 1 1 1 Initiation factor 2 subunit family PTS_EIIB PF00367.20 CBY10945.1 - 0.17 11.4 0.8 0.39 10.3 0.8 1.6 1 0 0 1 1 1 0 phosphotransferase system, EIIB TSP_1 PF00090.19 CBY10946.1 - 2.7e-07 30.7 9.9 9.2e-06 25.8 2.5 3.6 2 0 0 2 2 2 2 Thrombospondin type 1 domain PAN_1 PF00024.26 CBY10946.1 - 3.9e-06 26.7 9.1 0.016 15.1 0.7 3.4 2 0 0 2 2 2 2 PAN domain Kelch_4 PF13418.6 CBY10946.1 - 0.0018 18.3 1.3 12 6.0 0.1 4.5 4 1 0 4 4 4 2 Galactose oxidase, central domain PAN_4 PF14295.6 CBY10946.1 - 0.0054 16.6 2.9 0.0054 16.6 2.9 4.7 5 0 0 5 5 5 1 PAN domain GSHPx PF00255.19 CBY10948.1 - 3.9e-22 77.9 0.1 5.4e-22 77.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CBY10948.1 - 0.00036 20.5 0.1 0.00079 19.3 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family DnaJ PF00226.31 CBY10949.1 - 3.7e-06 26.9 1.8 0.0055 16.8 0.0 3.0 2 1 1 3 3 3 2 DnaJ domain CHASE9 PF17153.4 CBY10949.1 - 0.0093 16.1 0.2 0.6 10.3 0.0 2.4 2 0 0 2 2 2 1 Periplasmic sensor domain, extracellular DUF2027 PF09640.10 CBY10949.1 - 0.075 12.6 3.0 0.14 11.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2027) DUF4482 PF14818.6 CBY10949.1 - 9.7 7.1 14.4 5.7 7.8 7.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) EF-hand_7 PF13499.6 CBY10950.1 - 8.8e-06 26.1 0.1 1.6e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY10950.1 - 9.2e-05 22.1 0.4 0.00041 20.0 0.0 2.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CBY10950.1 - 0.00024 20.4 1.3 0.00035 19.9 0.1 2.0 3 0 0 3 3 3 1 EF hand CLCA PF08434.11 CBY10950.1 - 0.0056 16.0 0.2 0.0062 15.9 0.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal EF-hand_8 PF13833.6 CBY10950.1 - 0.027 14.3 0.1 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_9 PF14658.6 CBY10950.1 - 0.14 12.5 0.0 0.48 10.8 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain BSMAP PF12280.8 CBY10951.1 - 0.006 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Brain specific membrane anchored protein DUF4286 PF14114.6 CBY10951.1 - 0.11 12.9 0.3 0.43 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) zf-Di19 PF05605.12 CBY10952.1 - 0.0045 17.3 0.1 0.0045 17.3 0.1 5.4 4 2 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CBY10952.1 - 0.026 15.4 31.5 0.27 12.2 0.1 5.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY10952.1 - 0.12 12.1 4.5 0.96 9.3 4.5 2.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_12 PF18658.1 CBY10952.1 - 0.14 11.7 14.4 3.4 7.3 0.1 4.6 4 1 1 5 5 5 0 Zinc-finger C2H2-type DUF2321 PF10083.9 CBY10952.1 - 4.3 6.9 6.8 4.6 6.8 0.3 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) ECH_1 PF00378.20 CBY10953.1 - 4e-58 196.7 0.1 4.5e-58 196.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY10953.1 - 3.5e-30 105.6 0.1 6e-30 104.9 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ta0938 PF11494.8 CBY10955.1 - 0.0077 16.5 0.3 0.011 16.0 0.3 1.4 1 0 0 1 1 1 1 Ta0938 BPA_C PF18040.1 CBY10955.1 - 0.041 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 beta porphyranase A C-terminal zf-FCS PF06467.14 CBY10955.1 - 0.2 11.6 4.6 0.47 10.4 4.6 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif C1q PF00386.21 CBY10957.1 - 0.00045 20.4 2.1 0.00061 20.0 2.1 1.2 1 0 0 1 1 1 1 C1q domain FecR PF04773.13 CBY10957.1 - 0.13 12.9 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 FecR protein MBT PF02820.18 CBY10958.1 - 7.1e-54 180.1 1.0 6.1e-20 71.3 0.0 4.2 4 0 0 4 4 4 4 mbt repeat POPLD PF08170.12 CBY10958.1 - 0.033 14.5 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 POPLD (NUC188) domain DUF1583 PF07622.11 CBY10958.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) VPS13_C PF16909.5 CBY10959.1 - 1.7e-49 168.0 8.3 1.5e-45 155.1 1.6 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CBY10959.1 - 9.5e-36 123.8 9.8 1.1e-33 117.0 5.1 3.7 2 1 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CBY10959.1 - 9.2e-27 93.5 0.2 5.7e-26 90.9 0.1 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 CBY10959.1 - 2.2e-26 92.7 1.4 2.2e-26 92.7 1.4 3.8 4 0 0 4 4 4 1 Repeating coiled region of VPS13 SHR-BD PF06650.12 CBY10959.1 - 3.3e-24 85.7 0.5 2.8e-21 76.1 0.1 3.7 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CBY10959.1 - 1.7e-08 34.7 0.0 6.1e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein C terminal domain HU-CCDC81_bac_1 PF18174.1 CBY10960.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 UCH PF00443.29 CBY10962.1 - 8.3e-28 97.6 2.4 1.6e-27 96.7 2.4 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CBY10962.1 - 0.0029 17.4 0.8 0.0045 16.7 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf-RING_4 PF14570.6 CBY10962.1 - 3.9 7.4 14.0 15 5.5 14.0 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UCH_1 PF13423.6 CBY10962.1 - 5.7 6.4 25.5 0.4 10.2 15.0 3.3 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase ABC1 PF03109.16 CBY10963.1 - 4.2e-34 117.2 0.0 8.8e-34 116.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CBY10963.1 - 5.8e-07 29.1 0.0 0.00085 18.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 CBY10963.1 - 0.0018 18.3 0.1 0.013 15.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBY10963.1 - 0.04 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.22 CBY10964.1 - 2.2e-14 53.0 0.0 4.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.25 CBY10965.1 - 1.3e-10 41.1 0.1 1.9e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Bromodomain MurB_C PF02873.16 CBY10965.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Not3 PF04065.15 CBY10966.1 - 0.0011 18.4 2.4 0.0011 18.4 2.4 1.4 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component DED PF01335.21 CBY10966.1 - 0.028 14.7 2.6 0.052 13.9 2.6 1.4 1 0 0 1 1 1 0 Death effector domain GIDA_assoc PF13932.6 CBY10966.1 - 1.1 9.4 5.8 1.6 8.9 4.9 1.6 1 1 1 2 2 2 0 GidA associated domain SNF5 PF04855.12 CBY10967.1 - 1.4e-53 182.1 1.0 2.1e-28 99.7 0.0 2.7 1 1 2 3 3 3 2 SNF5 / SMARCB1 / INI1 GGDEF PF00990.21 CBY10967.1 - 0.091 12.5 0.4 0.19 11.4 0.4 1.5 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain LpoB PF13036.6 CBY10967.1 - 0.12 12.3 1.3 2.6 8.0 0.2 2.7 3 0 0 3 3 3 0 Peptidoglycan-synthase activator LpoB 40S_S4_C PF16121.5 CBY10968.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus ig PF00047.25 CBY10969.1 - 1.9e-16 60.0 8.2 8e-07 29.1 0.1 4.2 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 CBY10969.1 - 3.9e-15 56.2 13.4 0.00014 22.4 0.2 4.2 4 1 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY10969.1 - 9.2e-13 48.1 4.4 1.6e-07 31.3 0.1 3.0 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain I-set PF07679.16 CBY10969.1 - 3.9e-12 46.1 8.2 0.015 15.3 0.2 5.0 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY10969.1 - 8.4e-12 45.3 7.9 0.00044 20.5 0.1 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CBY10969.1 - 1.7e-09 37.8 4.2 4.4e-09 36.5 0.1 3.0 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY10969.1 - 7.1e-05 22.3 0.1 0.0048 16.4 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 CBY10969.1 - 0.0026 17.5 4.1 0.17 11.7 0.2 3.9 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 Glycophorin_A PF01102.18 CBY10969.1 - 0.025 14.8 0.0 0.082 13.1 0.0 1.9 1 0 0 1 1 1 0 Glycophorin A C1-set PF07654.15 CBY10969.1 - 0.063 13.7 4.5 0.13 12.7 0.4 3.2 3 1 0 3 3 3 0 Immunoglobulin C1-set domain Syndecan PF01034.20 CBY10969.1 - 0.45 10.5 3.2 1.9 8.5 3.2 2.0 2 0 0 2 2 2 0 Syndecan domain Mlh1_C PF16413.5 CBY10971.1 - 1e-44 153.0 2.8 1.5e-43 149.1 2.8 2.5 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CBY10971.1 - 9.5e-27 93.0 0.1 2e-26 92.0 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CBY10971.1 - 1e-15 57.7 0.1 2.3e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBY10971.1 - 1.8e-08 34.9 0.1 8.9e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lectin_legB PF00139.19 CBY10971.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Legume lectin domain CCDC50_N PF15295.6 CBY10972.1 - 7.3e-35 119.9 40.7 1.7e-34 118.7 14.6 4.8 2 1 3 5 5 5 3 Coiled-coil domain-containing protein 50 N-terminus AMP-binding PF00501.28 CBY10973.1 - 1.4e-86 290.8 0.0 1.7e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY10973.1 - 3e-19 69.8 0.3 6e-19 68.8 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CBY10973.1 - 4.1e-16 58.6 3.5 1.5e-15 56.9 2.9 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus URO-D PF01208.17 CBY10974.1 - 1.4e-125 419.1 0.0 1.6e-125 418.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) AMP-binding PF00501.28 CBY10975.1 - 4.9e-94 315.3 0.0 5.8e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY10975.1 - 8.5e-22 77.9 0.0 2e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CBY10975.1 - 9.8e-17 60.6 0.6 2.1e-16 59.5 0.2 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Galactosyl_T PF01762.21 CBY10976.1 - 5.2e-49 166.7 0.0 1.1e-48 165.6 0.0 1.5 2 0 0 2 2 2 1 Galactosyltransferase DUF604 PF04646.12 CBY10976.1 - 0.007 15.8 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Phage_int_SAM_1 PF02899.17 CBY10976.1 - 0.0091 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF2976 PF11190.8 CBY10976.1 - 0.088 12.6 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Imm58 PF15581.6 CBY10976.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 58 Ras PF00071.22 CBY10977.1 - 8.1e-44 149.1 0.0 1.1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY10977.1 - 2.2e-35 121.5 0.0 3.2e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY10977.1 - 4.6e-11 42.5 0.0 6.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY10977.1 - 1.2e-08 35.0 0.0 1.8e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY10977.1 - 3.1e-07 30.5 0.0 0.00017 21.6 0.1 2.5 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBY10977.1 - 4.7e-07 29.4 0.0 5.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CBY10977.1 - 0.00065 20.1 0.0 0.00087 19.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 CBY10977.1 - 0.0012 18.3 0.0 0.007 15.8 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY10977.1 - 0.0014 18.2 0.0 0.047 13.2 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TIR_2 PF13676.6 CBY10977.1 - 0.0042 17.7 0.0 0.0086 16.7 0.0 1.6 2 0 0 2 2 1 1 TIR domain AAA_7 PF12775.7 CBY10977.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 CBY10977.1 - 0.0079 15.7 0.1 0.051 13.1 0.0 2.1 2 1 1 3 3 3 1 Ferrous iron transport protein B PduV-EutP PF10662.9 CBY10977.1 - 0.0082 15.9 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 CBY10977.1 - 0.0087 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Septin PF00735.18 CBY10977.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CBY10977.1 - 0.016 14.5 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 CBY10977.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 CBY10977.1 - 0.035 13.3 0.1 4 6.5 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 CBY10977.1 - 0.044 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 CBY10977.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein IIGP PF05049.13 CBY10977.1 - 0.077 12.0 0.1 0.13 11.3 0.1 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 CBY10977.1 - 0.081 13.4 0.3 0.088 13.3 0.3 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CBY10977.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CBY10977.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CBY10977.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Shisa PF13908.6 CBY10980.1 - 0.0023 18.2 6.1 0.011 16.0 6.1 1.9 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator TMIE PF16038.5 CBY10980.1 - 0.24 11.3 1.7 0.37 10.7 1.7 1.2 1 0 0 1 1 1 0 TMIE protein Shisa PF13908.6 CBY10982.1 - 0.0023 18.2 6.1 0.011 16.0 6.1 1.9 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator TMIE PF16038.5 CBY10982.1 - 0.24 11.3 1.7 0.37 10.7 1.7 1.2 1 0 0 1 1 1 0 TMIE protein Pkinase PF00069.25 CBY10984.1 - 1.7e-51 175.2 0.1 2.6e-51 174.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY10984.1 - 5.9e-28 97.9 0.0 9.2e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY10984.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY10984.1 - 0.00083 18.8 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY10984.1 - 0.0023 16.8 0.0 0.0023 16.8 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CBY10984.1 - 0.016 14.8 0.2 0.051 13.2 0.1 1.9 2 0 0 2 2 2 0 RIO1 family Actin PF00022.19 CBY10985.1 - 1.5e-109 366.3 0.0 1.7e-109 366.2 0.0 1.0 1 0 0 1 1 1 1 Actin FtsA PF14450.6 CBY10985.1 - 0.04 14.3 0.1 0.2 12.1 0.0 2.2 2 1 0 2 2 2 0 Cell division protein FtsA RNase_T PF00929.24 CBY10986.1 - 0.00047 20.7 0.0 0.0032 18.0 0.0 2.2 1 1 0 1 1 1 1 Exonuclease zf-MYND PF01753.18 CBY10987.1 - 6.2e-06 26.2 10.0 1.7e-05 24.8 10.0 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CBY10987.1 - 0.0053 17.0 6.9 0.055 13.8 3.0 2.7 1 1 1 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Tup_N PF08581.10 CBY10987.1 - 0.018 15.3 6.8 0.018 15.3 6.8 2.5 2 0 0 2 2 2 0 Tup N-terminal PKcGMP_CC PF16808.5 CBY10987.1 - 0.13 12.2 0.4 0.13 12.2 0.4 4.2 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 CBY10987.1 - 0.76 9.9 28.2 9.8 6.2 12.7 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Ferritin PF00210.24 CBY10987.1 - 0.76 9.7 8.4 0.53 10.2 6.3 1.8 1 1 0 1 1 1 0 Ferritin-like domain DUF1664 PF07889.12 CBY10987.1 - 3.9 7.5 9.5 3 7.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 CBY10987.1 - 7.6 5.3 11.2 8.9 5.1 11.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EF1G PF00647.19 CBY10988.1 - 7.1e-39 132.2 0.1 1.3e-38 131.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CBY10988.1 - 1.3e-09 38.1 0.9 2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY10988.1 - 0.00019 21.4 0.1 0.00043 20.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY10988.1 - 0.00047 20.3 0.0 0.0018 18.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY10989.1 - 3.9e-07 30.3 0.0 4.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FoP_duplication PF13865.6 CBY10989.1 - 0.75 10.4 10.3 1 9.9 10.3 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SKIP_SNW PF02731.15 CBY10990.1 - 1.1e-71 239.7 2.7 1.1e-71 239.7 2.7 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Plasmodium_Vir PF05795.11 CBY10990.1 - 4.4 6.6 6.3 1.3 8.4 2.0 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein ALIX_LYPXL_bnd PF13949.6 CBY10991.1 - 2e-79 267.0 21.8 1e-78 264.6 10.6 2.3 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV BRO1 PF03097.18 CBY10991.1 - 1.3e-74 251.4 8.4 2.3e-74 250.5 8.4 1.4 1 0 0 1 1 1 1 BRO1-like domain CagS PF16707.5 CBY10991.1 - 0.055 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Xpo1 PF08389.12 CBY10991.1 - 0.18 11.9 1.0 0.64 10.1 0.6 2.2 1 1 0 1 1 1 0 Exportin 1-like protein DUF4709 PF15821.5 CBY10991.1 - 2.9 8.2 7.1 1.4 9.2 0.4 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4709) Peptidase_C2 PF00648.21 CBY10992.1 - 2.1e-05 23.7 0.0 3.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease IQ PF00612.27 CBY10992.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Band_7 PF01145.25 CBY10993.1 - 1.7e-09 38.0 0.0 2.7e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family SCP2 PF02036.17 CBY10993.1 - 0.0039 17.6 0.1 0.0074 16.8 0.1 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CBY10993.1 - 0.0092 16.3 0.1 0.023 15.0 0.0 1.7 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal TspO_MBR PF03073.15 CBY10993.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 TspO/MBR family Nup96 PF12110.8 CBY10994.1 - 5.4e-68 229.2 0.0 8.4e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CBY10994.1 - 1e-37 129.5 0.0 2.7e-37 128.2 0.0 1.8 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 CBY10994.1 - 8.2e-21 74.7 107.2 1.6e-07 32.0 32.8 4.0 1 1 2 3 3 3 3 Nucleoporin FG repeat region Helicase_PWI PF18149.1 CBY10994.1 - 0.038 14.2 0.2 0.13 12.5 0.2 1.9 1 0 0 1 1 1 0 N-terminal helicase PWI domain Neuraminidase PF18413.1 CBY10994.1 - 0.3 10.7 1.8 26 4.4 0.1 3.2 2 1 1 3 3 3 0 Neuraminidase-like domain Nucleoporin_FG PF13634.6 CBY10995.1 - 4.6e-11 43.4 75.4 7.8e-05 23.5 27.5 3.6 2 2 0 2 2 2 2 Nucleoporin FG repeat region Ank_2 PF12796.7 CBY10996.1 - 2.2e-11 44.2 0.2 4.2e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY10996.1 - 5.3e-10 39.6 0.2 0.00016 22.1 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY10996.1 - 1.1e-09 38.4 0.1 0.0005 20.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DZR PF12773.7 CBY10996.1 - 1.2e-08 34.8 44.5 3.7e-05 23.7 10.9 3.8 2 1 1 3 3 3 3 Double zinc ribbon Fn3_assoc PF13287.6 CBY10996.1 - 1.5e-07 31.4 0.0 5e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Fn3 associated Ank PF00023.30 CBY10996.1 - 7.1e-06 26.2 1.1 0.011 16.2 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat CHB_HEX_C_1 PF13290.6 CBY10996.1 - 2.4e-05 24.3 0.0 6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Ank_3 PF13606.6 CBY10996.1 - 3.6e-05 23.8 0.1 0.29 11.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat CHB_HEX_C_1 PF13290.6 CBY10997.1 - 1.3e-09 38.0 0.4 3.2e-09 36.6 0.4 1.7 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 CBY10997.1 - 7.3e-09 35.7 0.2 1.6e-08 34.5 0.2 1.7 1 0 0 1 1 1 1 Fn3 associated Ank_2 PF12796.7 CBY10997.1 - 1.5e-05 25.4 0.0 3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY10997.1 - 0.00023 21.7 0.0 0.13 12.9 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DZR PF12773.7 CBY10997.1 - 0.00027 20.9 0.2 0.00055 19.9 0.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon Ank_3 PF13606.6 CBY10997.1 - 0.001 19.3 0.0 2.3 9.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat zinc_ribbon_2 PF13240.6 CBY10997.1 - 0.025 14.3 2.5 0.052 13.3 2.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF5094 PF17015.5 CBY10997.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) zf-ribbon_3 PF13248.6 CBY10997.1 - 0.15 11.5 3.5 0.14 11.6 1.8 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 CBY10997.1 - 0.19 12.5 0.1 0.4 11.5 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family zf-RanBP PF00641.18 CBY10997.1 - 0.43 9.9 4.4 0.12 11.8 0.9 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Phage_Mu_Gam PF07352.12 CBY10997.1 - 1.6 8.6 5.0 0.67 9.8 0.9 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF5427 PF10310.9 CBY10997.1 - 2.1 7.2 10.1 0.42 9.5 5.8 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5427) FGGY_C PF02782.16 CBY10998.1 - 1e-43 149.4 0.3 3e-43 147.9 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CBY10998.1 - 2.9e-19 69.6 0.0 5.6e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 CBY10998.1 - 0.002 17.6 0.9 0.88 9.0 0.1 2.5 2 1 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family MMS1_N PF10433.9 CBY10999.1 - 1.5e-166 554.9 0.0 6.9e-166 552.7 0.0 2.1 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CBY10999.1 - 2.6e-80 270.2 0.0 9.9e-80 268.2 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 CBY10999.1 - 0.072 13.4 0.0 4.1 7.8 0.0 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Dpy-30 PF05186.13 CBY11000.1 - 1e-07 31.5 0.0 1.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif KH_1 PF00013.29 CBY11001.1 - 6.5e-26 89.9 3.0 4.2e-11 42.5 0.3 3.8 3 1 0 3 3 3 3 KH domain KH_2 PF07650.17 CBY11001.1 - 0.0004 20.2 1.9 0.35 10.7 0.1 2.6 2 0 0 2 2 2 2 KH domain MutS_IV PF05190.18 CBY11002.1 - 0.21 11.9 4.9 1.6 9.1 0.6 3.7 3 1 1 4 4 4 0 MutS family domain IV SWIB PF02201.18 CBY11003.1 - 2.2e-21 75.5 0.1 5.9e-21 74.1 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain FlxA PF14282.6 CBY11004.1 - 5.1e-05 23.2 7.5 5.1e-05 23.2 7.5 2.7 1 1 0 2 2 1 1 FlxA-like protein NYD-SP28 PF14772.6 CBY11004.1 - 0.0045 17.0 13.3 0.0045 17.0 13.3 2.7 1 1 2 3 3 3 1 Sperm tail SH3BP5 PF05276.14 CBY11004.1 - 0.014 15.2 1.9 0.014 15.2 1.9 2.1 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) DUF1786 PF08735.10 CBY11004.1 - 0.021 14.1 0.3 0.024 13.9 0.3 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) NPV_P10 PF05531.12 CBY11004.1 - 0.036 14.5 1.4 0.39 11.2 0.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.11 CBY11004.1 - 0.053 13.4 9.9 0.068 13.0 9.0 1.6 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) AAA_15 PF13175.6 CBY11004.1 - 0.088 12.5 17.7 0.11 12.2 17.7 1.1 1 0 0 1 1 1 0 AAA ATPase domain FliD_C PF07195.12 CBY11004.1 - 0.13 11.6 10.8 0.27 10.6 10.8 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus BrnA_antitoxin PF14384.6 CBY11004.1 - 0.23 12.0 2.1 0.68 10.5 2.1 1.9 1 1 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system Golgin_A5 PF09787.9 CBY11004.1 - 0.3 10.5 22.3 0.38 10.2 22.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 MitMem_reg PF13012.6 CBY11004.1 - 0.61 10.5 5.6 0.39 11.2 3.2 1.8 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function DUF445 PF04286.12 CBY11004.1 - 0.71 9.6 11.3 0.92 9.3 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1664 PF07889.12 CBY11004.1 - 0.92 9.5 12.4 0.096 12.7 6.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3573 PF12097.8 CBY11004.1 - 1.5 7.6 4.0 3 6.6 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4407 PF14362.6 CBY11004.1 - 1.9 7.7 14.4 0.16 11.3 8.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nup88 PF10168.9 CBY11004.1 - 2.6 5.7 19.1 3.2 5.5 19.1 1.1 1 0 0 1 1 1 0 Nuclear pore component Exonuc_VII_L PF02601.15 CBY11004.1 - 3.1 7.3 13.3 3.8 7.0 13.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Amino_oxidase PF01593.24 CBY11005.1 - 3.9e-22 79.2 0.0 4.8e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CBY11005.1 - 9.4e-07 29.0 0.3 3.3e-06 27.2 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DC_STAMP PF07782.13 CBY11006.1 - 7.4e-35 120.5 0.0 2.3e-34 118.9 0.0 1.7 2 0 0 2 2 2 1 DC-STAMP-like protein zf-RING_5 PF14634.6 CBY11007.1 - 2.3e-06 27.5 7.8 3.2e-06 27.0 7.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY11007.1 - 4.3e-06 26.5 8.9 2.7e-05 24.0 8.6 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY11007.1 - 6.4e-06 25.9 8.2 1.3e-05 24.9 8.2 1.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY11007.1 - 1.1e-05 25.1 7.2 1.6e-05 24.6 7.2 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CBY11007.1 - 2.4e-05 24.6 8.4 3.4e-05 24.1 8.4 1.2 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 CBY11007.1 - 0.00012 21.5 1.4 0.00012 21.5 1.4 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Baculo_IE-1 PF05290.11 CBY11007.1 - 0.0075 16.2 3.1 0.011 15.6 3.1 1.4 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 CBY11007.1 - 0.012 15.6 6.9 0.015 15.3 2.6 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY11007.1 - 0.019 14.8 9.7 0.041 13.7 9.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY11007.1 - 0.034 14.0 8.6 1 9.3 9.3 2.5 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 CBY11007.1 - 0.064 13.5 9.1 0.29 11.4 8.4 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF1272 PF06906.11 CBY11007.1 - 0.081 13.0 6.5 0.12 12.5 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_1 PF14446.6 CBY11007.1 - 0.1 12.5 10.7 1.7 8.6 5.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 CBY11007.1 - 0.1 12.4 2.0 3.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_5 PF13719.6 CBY11007.1 - 0.17 11.6 0.2 0.17 11.6 0.2 3.3 2 1 0 2 2 1 0 zinc-ribbon domain DZR PF12773.7 CBY11007.1 - 0.18 11.8 9.7 2.8 8.1 9.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon YacG PF03884.14 CBY11007.1 - 0.2 11.4 5.3 2.7 7.8 1.9 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG FYVE PF01363.21 CBY11007.1 - 0.32 11.2 11.3 0.29 11.3 5.5 2.1 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_10 PF16685.5 CBY11007.1 - 0.38 10.9 7.2 0.53 10.5 7.0 1.4 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 CBY11007.1 - 1 9.6 7.6 35 4.7 8.5 2.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DNA_RNApol_7kD PF03604.13 CBY11007.1 - 3.7 7.3 9.9 0.97 9.2 2.3 3.0 1 1 2 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 CBY11007.1 - 4.7 7.3 7.5 57 3.8 7.5 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CP2 PF04516.15 CBY11008.1 - 7.9e-62 208.6 1.1 1.3e-61 207.8 1.1 1.3 1 0 0 1 1 1 1 CP2 transcription factor DUF4231 PF14015.6 CBY11008.1 - 0.12 12.8 0.3 0.23 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3340 PF11818.8 CBY11008.1 - 7.8 6.6 7.8 0.4 10.8 1.1 2.3 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Dpy19 PF10034.9 CBY11009.1 - 1.4e-219 730.7 7.5 1.6e-219 730.5 7.5 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation KNOX1 PF03790.13 CBY11009.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 KNOX1 domain STAG PF08514.11 CBY11011.1 - 1.1e-30 105.9 1.7 5.7e-30 103.5 0.9 2.7 2 0 0 2 2 2 1 STAG domain HEAT PF02985.22 CBY11011.1 - 0.017 15.4 3.2 0.024 14.9 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 CBY11011.1 - 0.022 14.8 0.3 0.14 12.2 0.3 2.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 RCR PF12273.8 CBY11011.1 - 7.4 7.3 8.5 16 6.2 8.5 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red zf-met PF12874.7 CBY11012.1 - 3.1e-13 49.6 15.6 2.9e-07 30.6 0.2 4.4 3 1 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY11012.1 - 3.1e-06 27.4 13.7 0.006 16.9 0.6 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY11012.1 - 0.00045 20.4 0.8 0.00045 20.4 0.8 4.6 5 1 0 5 5 5 1 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 CBY11012.1 - 0.0063 15.7 1.4 1.2 8.2 0.0 2.6 2 1 0 2 2 2 2 Putative actin-like family zf-C2H2_4 PF13894.6 CBY11012.1 - 0.0071 17.1 8.3 0.13 13.2 0.1 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 CBY11012.1 - 0.16 12.1 1.9 42 4.3 0.2 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 CBY11012.1 - 3.3 7.6 10.8 7 6.6 0.2 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Rhomboid PF01694.22 CBY11013.1 - 1.9e-30 105.8 11.0 1.9e-30 105.8 11.0 1.9 1 1 1 2 2 2 1 Rhomboid family GtrA PF04138.14 CBY11013.1 - 2.8 8.2 15.7 0.053 13.8 7.3 2.3 3 0 0 3 3 3 0 GtrA-like protein Peptidase_A8 PF01252.18 CBY11013.1 - 6.6 7.0 8.5 3.1 8.0 3.0 2.5 1 1 1 2 2 2 0 Signal peptidase (SPase) II Pyr_redox_2 PF07992.14 CBY11014.1 - 1.3e-08 34.4 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CBY11015.1 - 1.7e-08 34.1 0.1 1.8e-08 34.0 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY11015.1 - 3.3e-07 30.4 0.1 4.6e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CBY11015.1 - 1.6e-06 28.0 0.1 1.8e-06 27.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBY11015.1 - 4.6e-06 26.0 0.1 5.1e-06 25.8 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 CBY11015.1 - 6.2e-05 22.0 0.1 6.5e-05 22.0 0.1 1.0 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 CBY11015.1 - 7.3e-05 22.2 0.0 7.9e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CBY11015.1 - 8.4e-05 21.9 0.0 8.9e-05 21.8 0.0 1.0 1 0 0 1 1 1 1 Thi4 family ThiF PF00899.21 CBY11015.1 - 0.00036 20.0 0.0 0.00039 19.8 0.0 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CBY11015.1 - 0.00041 20.6 0.1 0.0005 20.3 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 CBY11015.1 - 0.00044 20.3 0.0 0.00049 20.1 0.0 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding TrkA_N PF02254.18 CBY11015.1 - 0.0011 19.2 0.0 0.0015 18.8 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 CBY11015.1 - 0.0021 17.4 0.0 0.0026 17.1 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBY11015.1 - 0.0021 16.8 0.1 0.0024 16.7 0.1 1.0 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 CBY11015.1 - 0.0024 17.5 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CBY11015.1 - 0.0036 17.4 0.0 0.0036 17.4 0.0 1.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 CBY11015.1 - 0.0073 15.9 0.1 0.0086 15.7 0.1 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 CBY11015.1 - 0.0083 16.7 0.1 0.01 16.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBY11015.1 - 0.016 14.3 0.2 0.017 14.2 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CBY11015.1 - 0.017 14.2 0.0 0.018 14.1 0.0 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CBY11015.1 - 0.017 14.4 0.1 0.018 14.4 0.1 1.0 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CBY11015.1 - 0.028 14.8 0.1 0.031 14.7 0.1 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CBY11015.1 - 0.035 14.0 0.2 0.042 13.7 0.2 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CBY11015.1 - 0.093 13.3 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_oxidored PF12831.7 CBY11015.1 - 0.12 11.8 0.6 0.12 11.7 0.6 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 CBY11015.1 - 0.12 11.8 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AAA_16 PF13191.6 CBY11016.1 - 4.5e-06 27.1 0.0 6.8e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 CBY11016.1 - 6.5e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 CBY11016.1 - 4.2e-05 23.8 0.0 8.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBY11016.1 - 4.7e-05 23.6 0.0 0.00017 21.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBY11016.1 - 0.00019 22.0 0.0 0.00039 21.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 CBY11016.1 - 0.00064 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 CBY11016.1 - 0.00076 20.0 0.0 0.0012 19.3 0.0 1.5 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 CBY11016.1 - 0.00086 19.3 0.0 0.0018 18.2 0.0 1.5 1 1 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 CBY11016.1 - 0.0009 18.6 0.0 0.0023 17.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 CBY11016.1 - 0.0014 18.6 0.1 0.0055 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRP54 PF00448.22 CBY11016.1 - 0.0025 17.5 0.0 0.0067 16.1 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CBY11016.1 - 0.0025 17.5 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CPT PF07931.12 CBY11016.1 - 0.0034 17.3 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 CBY11016.1 - 0.0055 17.1 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 CBY11016.1 - 0.0065 16.4 0.1 0.024 14.6 0.0 1.9 3 0 0 3 3 2 1 RsgA GTPase APS_kinase PF01583.20 CBY11016.1 - 0.0076 16.2 0.0 0.013 15.4 0.0 1.4 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_14 PF13173.6 CBY11016.1 - 0.0076 16.3 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBY11016.1 - 0.0087 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_PrkA PF08298.11 CBY11016.1 - 0.009 15.0 0.0 0.014 14.3 0.0 1.5 1 1 0 1 1 1 1 PrkA AAA domain DUF815 PF05673.13 CBY11016.1 - 0.019 14.2 0.1 0.034 13.3 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 CBY11016.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 CBY11016.1 - 0.021 14.6 0.0 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase AAA PF00004.29 CBY11016.1 - 0.024 15.1 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CBY11016.1 - 0.024 13.7 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.20 CBY11016.1 - 0.029 13.6 0.1 0.039 13.1 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.22 CBY11016.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 CBY11016.1 - 0.042 13.8 0.1 0.066 13.1 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CBY11016.1 - 0.049 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CBY11016.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 CBY11016.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 CBY11016.1 - 0.079 12.3 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3452 PF11934.8 CBY11016.1 - 0.089 12.3 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Sigma54_activat PF00158.26 CBY11016.1 - 0.093 12.4 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 CBY11016.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 CBY11016.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 CBY11016.1 - 0.26 10.3 0.0 0.4 9.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PAX PF00292.18 CBY11017.1 - 1.3e-67 225.5 0.8 2.1e-67 224.7 0.8 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CBY11017.1 - 1.7e-05 24.4 0.0 3.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 CBY11017.1 - 5.9e-05 23.6 0.0 0.23 12.1 0.0 2.6 1 1 1 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 CBY11017.1 - 0.0033 17.1 0.7 0.0076 16.0 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 CBY11017.1 - 0.0038 16.8 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 InsA C-terminal domain HTH_29 PF13551.6 CBY11017.1 - 0.0096 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 CBY11017.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 CBY11017.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 MarR family Far-17a_AIG1 PF04750.14 CBY11018.1 - 1.8e-06 27.4 3.3 3.7e-06 26.4 3.3 1.6 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein CTP_transf_1 PF01148.20 CBY11018.1 - 0.14 11.9 5.0 0.18 11.5 5.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family E1-E2_ATPase PF00122.20 CBY11018.1 - 0.27 10.7 2.2 0.21 11.1 0.3 1.7 1 1 1 2 2 2 0 E1-E2 ATPase DnaJ PF00226.31 CBY11020.1 - 1.6e-07 31.3 1.4 0.0021 18.1 0.2 3.0 2 1 1 3 3 3 2 DnaJ domain Tricorn_C1 PF14684.6 CBY11020.1 - 0.04 14.0 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain UQ_con PF00179.26 CBY11022.1 - 5.2e-15 55.3 0.0 8.1e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_transf_64 PF09258.10 CBY11023.1 - 3.5e-76 255.7 0.0 4.8e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 CBY11023.1 - 3.4e-49 167.7 0.0 6.6e-49 166.7 0.0 1.5 2 0 0 2 2 2 1 Exostosin family E1_dh PF00676.20 CBY11024.1 - 7.6e-109 363.3 0.0 8.9e-109 363.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CBY11024.1 - 0.00059 19.1 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 CBY11024.1 - 0.0023 17.0 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Tubulin PF00091.25 CBY11027.1 - 0.1 12.8 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Adaptin_N PF01602.20 CBY11028.1 - 5.7e-132 440.9 2.2 6.8e-132 440.7 2.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CBY11028.1 - 4e-19 69.0 0.9 8.1e-19 68.0 0.9 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CBY11028.1 - 4.1e-11 43.2 1.5 9.4e-07 29.0 0.1 2.9 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CBY11028.1 - 0.0012 18.8 4.4 9.3 6.5 0.1 6.1 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat Kinetochor_Ybp2 PF08568.10 CBY11028.1 - 0.0041 15.7 0.0 0.0075 14.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HEAT_2 PF13646.6 CBY11028.1 - 0.0074 16.7 0.1 0.69 10.3 0.0 4.0 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.22 CBY11028.1 - 0.033 14.4 1.3 3.9 8.0 0.1 4.8 5 0 0 5 5 5 0 HEAT repeat Guanylate_kin PF00625.21 CBY11029.1 - 5.5e-34 117.4 0.0 5.5e-34 117.4 0.0 2.6 3 0 0 3 3 3 1 Guanylate kinase SH3_1 PF00018.28 CBY11029.1 - 1.5e-05 24.5 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PDZ PF00595.24 CBY11029.1 - 0.00021 21.6 0.1 0.00048 20.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 CBY11029.1 - 0.00024 20.8 0.4 0.00073 19.3 0.1 2.0 2 0 0 2 2 2 1 L27 domain SH3_2 PF07653.17 CBY11029.1 - 0.00064 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CBY11029.1 - 0.0019 18.0 0.1 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Lipase_GDSL_2 PF13472.6 CBY11030.1 - 3.6e-24 86.1 0.0 4.6e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CBY11030.1 - 3.4e-14 53.3 0.0 5.9e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase COesterase PF00135.28 CBY11031.1 - 2e-86 290.9 0.1 7.6e-86 289.0 0.0 1.8 1 1 1 2 2 2 1 Carboxylesterase family Tctex-1 PF03645.13 CBY11031.1 - 1.1e-13 51.3 0.8 2.3e-13 50.3 0.8 1.6 1 0 0 1 1 1 1 Tctex-1 family Abhydrolase_3 PF07859.13 CBY11031.1 - 1.1e-08 35.2 1.0 8.7e-05 22.5 0.3 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3801 PF12687.7 CBY11032.1 - 0.25 11.4 24.6 1 9.4 5.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Syntaxin_2 PF14523.6 CBY11033.1 - 0.045 14.1 1.1 0.62 10.5 0.1 2.6 2 0 0 2 2 2 0 Syntaxin-like protein RVT_3 PF13456.6 CBY11034.1 - 0.0036 17.1 0.2 0.0078 16.0 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Dam PF05869.11 CBY11034.1 - 0.044 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) RVT_1 PF00078.27 CBY11036.1 - 0.049 13.1 0.2 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Dynein_light PF01221.18 CBY11037.1 - 0.00088 19.5 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 TMEM154 PF15102.6 CBY11038.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 CBY11038.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 CBY11038.1 - 0.055 13.8 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Prominin PF05478.11 CBY11038.1 - 0.065 11.2 0.0 0.079 10.9 0.0 1.1 1 0 0 1 1 1 0 Prominin DUF3377 PF11857.8 CBY11038.1 - 0.09 12.7 1.1 0.16 11.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RAMP PF04901.13 CBY11038.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Receptor activity modifying family Insulin_TMD PF17870.1 CBY11038.1 - 0.51 10.4 3.1 0.8 9.8 3.1 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment fn3 PF00041.21 CBY11039.1 - 2.4e-06 27.8 0.0 6.3e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III domain Metallophos PF00149.28 CBY11045.1 - 8.9e-09 36.1 0.1 1e-08 35.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase E1-E2_ATPase PF00122.20 CBY11046.1 - 9e-31 106.8 1.7 1.5e-30 106.1 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBY11046.1 - 1.7e-17 64.4 0.0 3.4e-17 63.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBY11046.1 - 2.8e-05 23.7 0.6 0.0002 21.0 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 CBY11046.1 - 0.025 15.0 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY11046.1 - 0.15 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Mucin2_WxxW PF13330.6 CBY11047.1 - 1.8e-154 503.0 106.8 1e-14 55.1 1.8 13.9 14 0 0 14 14 14 13 Mucin-2 protein WxxW repeating region Galactosyl_T PF01762.21 CBY11048.1 - 3.6e-21 75.9 0.0 9.2e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase RepL PF05732.11 CBY11048.1 - 0.075 12.5 2.6 0.19 11.2 0.7 2.1 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) COesterase PF00135.28 CBY11050.1 - 2.5e-79 267.5 0.0 3.4e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY11050.1 - 3.7e-05 23.7 1.2 0.00032 20.6 1.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY11050.1 - 0.001 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Trypsin PF00089.26 CBY11051.1 - 1.2e-36 126.7 0.3 4.5e-36 124.7 0.0 1.8 2 0 0 2 2 2 1 Trypsin EGF PF00008.27 CBY11051.1 - 2e-10 40.8 38.6 7.2e-07 29.4 7.8 4.2 3 0 0 3 3 3 3 EGF-like domain EGF_CA PF07645.15 CBY11051.1 - 2.9e-06 27.4 10.2 2.9e-06 27.4 10.2 4.6 4 1 1 5 5 5 1 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 CBY11051.1 - 3.4e-06 27.0 4.3 3.4e-06 27.0 4.3 3.9 4 0 0 4 4 4 1 MSP1 EGF domain 1 EGF_3 PF12947.7 CBY11051.1 - 0.00032 20.8 7.1 0.00032 20.8 7.1 4.1 3 0 0 3 3 3 1 EGF domain hEGF PF12661.7 CBY11051.1 - 0.00038 21.0 6.2 0.00038 21.0 6.2 4.6 3 0 0 3 3 3 1 Human growth factor-like EGF DUF1986 PF09342.11 CBY11051.1 - 0.0048 17.3 0.0 0.0093 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) EGF_2 PF07974.13 CBY11051.1 - 0.005 17.2 40.7 0.034 14.5 10.3 4.2 3 0 0 3 3 3 2 EGF-like domain Trypsin_2 PF13365.6 CBY11051.1 - 0.026 15.4 0.0 0.067 14.1 0.0 1.7 1 1 0 1 1 1 0 Trypsin-like peptidase domain FXa_inhibition PF14670.6 CBY11051.1 - 1.9 8.8 30.1 0.33 11.3 7.4 4.4 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site CAP PF00188.26 CBY11052.1 - 3.2e-38 131.4 3.2 7.3e-20 72.1 0.4 2.5 2 1 1 3 3 3 2 Cysteine-rich secretory protein family Sugar_tr PF00083.24 CBY11053.1 - 2.1e-21 76.4 4.1 3e-21 75.8 4.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY11053.1 - 6.3e-14 51.7 10.6 6.3e-14 51.7 10.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 CBY11054.1 - 4.2e-09 35.8 5.8 4.8e-09 35.6 5.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY11054.1 - 1e-06 27.9 7.2 1.2e-06 27.7 7.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Gate PF07670.14 CBY11054.1 - 0.04 14.2 0.1 0.13 12.6 0.1 2.0 1 1 0 1 1 1 0 Nucleoside recognition Transport_MerF PF11431.8 CBY11054.1 - 4.8 7.1 6.5 1.1 9.2 0.7 2.7 2 1 1 3 3 3 0 Membrane transport protein MerF SBF PF01758.16 CBY11055.1 - 1.5e-25 90.1 15.1 1.5e-25 90.1 15.1 1.8 1 1 1 2 2 2 1 Sodium Bile acid symporter family Comm PF15957.5 CBY11056.1 - 0.72 10.2 4.4 4.9 7.5 4.3 2.1 1 1 0 1 1 1 0 Commissureless MLANA PF14991.6 CBY11057.1 - 0.0063 16.8 0.1 0.0074 16.6 0.1 1.1 1 0 0 1 1 1 1 Protein melan-A DegS PF05384.11 CBY11057.1 - 0.18 11.3 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Sensor protein DegS WBP-1 PF11669.8 CBY11057.1 - 0.19 12.4 1.4 0.25 12.0 1.4 1.3 1 1 0 1 1 1 0 WW domain-binding protein 1 Zona_pellucida PF00100.23 CBY11058.1 - 5.5e-22 78.8 0.8 6.1e-22 78.6 0.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain ZoocinA_TRD PF16775.5 CBY11058.1 - 0.039 14.1 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme DUF5408 PF17402.2 CBY11059.1 - 0.048 13.6 0.6 0.1 12.5 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5408) MLANA PF14991.6 CBY11060.1 - 0.0063 16.8 0.1 0.0074 16.6 0.1 1.1 1 0 0 1 1 1 1 Protein melan-A DegS PF05384.11 CBY11060.1 - 0.18 11.3 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Sensor protein DegS WBP-1 PF11669.8 CBY11060.1 - 0.19 12.4 1.4 0.25 12.0 1.4 1.3 1 1 0 1 1 1 0 WW domain-binding protein 1 Zona_pellucida PF00100.23 CBY11061.1 - 4.2e-39 134.9 6.3 5.3e-39 134.6 6.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain CPSase_sm_chain PF00988.22 CBY11061.1 - 0.12 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain DUF2179 PF10035.9 CBY11062.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) Galactosyl_T PF01762.21 CBY11064.1 - 1.7e-18 67.2 0.4 2.4e-18 66.7 0.4 1.2 1 0 0 1 1 1 1 Galactosyltransferase Gemini_AL1 PF00799.20 CBY11065.1 - 0.0059 17.0 2.6 0.23 11.8 0.6 2.5 2 0 0 2 2 2 2 Geminivirus Rep catalytic domain DUF5512 PF17631.2 CBY11065.1 - 0.78 9.8 7.7 0.098 12.7 0.5 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5512) PAN_1 PF00024.26 CBY11067.1 - 1.6e-05 24.8 7.9 2e-05 24.4 7.9 1.2 1 0 0 1 1 1 1 PAN domain Adap_comp_sub PF00928.21 CBY11068.1 - 1.3e-07 31.3 1.0 1.4e-07 31.2 1.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 CBY11068.1 - 3.5e-06 26.7 1.0 4e-06 26.5 1.0 1.0 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Palm_thioest PF02089.15 CBY11070.1 - 1.8e-32 113.1 0.0 2e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Adap_comp_sub PF00928.21 CBY11071.1 - 5.1e-10 39.2 1.1 8.2e-10 38.5 1.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 CBY11071.1 - 3.3e-05 23.5 0.7 6.1e-05 22.6 0.7 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Palm_thioest PF02089.15 CBY11072.1 - 3e-64 217.1 0.0 3.4e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Palm_thioest PF02089.15 CBY11073.1 - 1.3e-15 57.9 0.0 1.4e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase HECW_N PF16562.5 CBY11073.1 - 0.17 11.7 0.2 0.28 11.0 0.1 1.4 1 1 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Lig_chan PF00060.26 CBY11074.1 - 3.9e-25 88.4 0.1 5.8e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CBY11074.1 - 1e-15 57.9 0.0 1.6e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CBY11074.1 - 1.7e-14 53.8 0.0 1.7e-13 50.6 0.0 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2407_C PF13373.6 CBY11074.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain Phospholip_A2_1 PF00068.19 CBY11075.1 - 2.2e-20 73.2 7.9 2.2e-20 73.2 7.9 2.3 2 1 0 2 2 2 1 Phospholipase A2 Lig_chan PF00060.26 CBY11076.1 - 1.2e-18 67.3 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 CBY11076.1 - 0.00017 21.1 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2407_C PF13373.6 CBY11076.1 - 0.013 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Phospholip_A2_1 PF00068.19 CBY11077.1 - 6.9e-20 71.6 8.8 6.9e-20 71.6 8.8 2.3 2 0 0 2 2 2 1 Phospholipase A2 CpxA_peri PF16527.5 CBY11079.1 - 0.19 12.1 4.3 0.32 11.4 2.0 2.5 2 1 1 3 3 3 0 Two-component sensor protein CpxA, periplasmic domain DUF948 PF06103.11 CBY11079.1 - 0.55 10.5 2.0 2.9 8.2 0.5 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) GCN5L1 PF06320.13 CBY11079.1 - 0.58 10.3 6.6 0.22 11.7 3.1 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) CD20 PF04103.15 CBY11080.1 - 0.00016 21.8 6.9 0.00025 21.1 5.4 2.0 1 1 0 1 1 1 1 CD20-like family PMP22_Claudin PF00822.20 CBY11080.1 - 0.01 15.7 0.7 2.4 8.0 0.0 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF202 PF02656.15 CBY11080.1 - 0.014 15.8 0.7 0.014 15.8 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) MerC PF03203.14 CBY11080.1 - 0.1 13.1 4.3 0.18 12.3 3.7 1.6 1 1 1 2 2 2 0 MerC mercury resistance protein DUF5357 PF17310.2 CBY11080.1 - 0.17 10.4 2.2 0.25 9.9 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) DUF308 PF03729.13 CBY11080.1 - 4 7.8 15.2 3.3 8.1 0.3 2.6 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) Thymosin PF01290.20 CBY11081.1 - 3.8e-57 189.7 64.7 3e-10 39.6 2.4 10.2 9 1 1 10 10 10 10 Thymosin beta-4 family WH2 PF02205.20 CBY11081.1 - 1.6e-06 27.7 34.0 2.2 8.2 0.0 9.1 10 0 0 10 10 10 6 WH2 motif Pentapeptide_4 PF13599.6 CBY11081.1 - 0.00066 19.8 11.8 0.092 12.9 0.3 4.7 3 2 1 4 4 4 2 Pentapeptide repeats (9 copies) Prot_ATP_ID_OB PF16450.5 CBY11081.1 - 0.045 13.7 1.2 28 4.8 0.1 3.4 3 0 0 3 3 3 0 Proteasomal ATPase OB C-terminal domain DUF4476 PF14771.6 CBY11081.1 - 0.11 12.8 21.0 0.41 11.0 1.5 5.2 3 1 4 7 7 7 0 Domain of unknown function (DUF4476) DUF2963 PF11178.8 CBY11081.1 - 0.22 11.2 8.2 2.8 7.7 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) RHH_8 PF17723.1 CBY11081.1 - 0.73 10.0 8.1 17 5.6 0.2 4.2 2 1 4 6 6 6 0 Ribbon-Helix-Helix transcriptional regulator family NOD2_WH PF17779.1 CBY11081.1 - 3.3 8.1 5.7 9.8 6.6 0.0 4.2 5 1 1 6 6 6 0 NOD2 winged helix domain DUF4522 PF15022.6 CBY11081.1 - 8.9 6.6 21.2 30 4.9 0.3 5.7 1 1 6 7 7 7 0 Protein of unknown function (DUF4522) O-FucT PF10250.9 CBY11082.1 - 0.054 13.2 0.1 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase zf_C2H2_6 PF18450.1 CBY11083.1 - 0.14 11.9 0.4 0.32 10.7 0.4 1.6 1 0 0 1 1 1 0 Zinc Finger domain Tetraspanin PF00335.20 CBY11084.1 - 1.9e-23 83.4 11.8 4.8e-23 82.1 11.8 1.6 1 1 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 CBY11084.1 - 2.7e-05 24.3 0.2 2.7e-05 24.3 0.2 2.3 2 1 1 3 3 3 1 CD20-like family Cyt_bd_oxida_I PF01654.17 CBY11084.1 - 0.034 12.8 1.9 0.065 11.8 1.5 1.7 1 1 1 2 2 2 0 Cytochrome bd terminal oxidase subunit I TctB PF07331.11 CBY11084.1 - 0.65 10.3 6.2 7.3 6.9 3.8 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family FixS PF03597.15 CBY11084.1 - 1.2 8.9 3.6 0.6 9.9 0.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Flavi_M PF01004.19 CBY11085.1 - 0.14 11.9 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M SOAR PF16533.5 CBY11086.1 - 1e-28 99.3 4.9 1e-28 99.3 4.9 3.1 3 0 0 3 3 3 1 STIM1 Orai1-activating region SAM_2 PF07647.17 CBY11086.1 - 2.9e-05 24.1 0.1 9.1e-05 22.5 0.1 1.9 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY11086.1 - 0.009 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_8 PF13833.6 CBY11086.1 - 0.01 15.7 1.1 0.26 11.2 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY11086.1 - 0.057 13.4 5.2 4.8 7.4 0.0 3.9 3 1 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 CBY11086.1 - 0.087 12.4 7.5 0.088 12.4 0.0 3.4 4 0 0 4 4 4 0 EF hand MARCKS PF02063.17 CBY11086.1 - 0.12 12.4 5.2 0.21 11.6 5.2 1.4 1 0 0 1 1 1 0 MARCKS family DUF2639 PF11121.8 CBY11086.1 - 0.16 12.1 0.3 0.59 10.2 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) EF-hand_7 PF13499.6 CBY11086.1 - 0.43 11.1 6.3 1.3 9.5 1.0 3.7 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_5 PF13202.6 CBY11086.1 - 0.53 9.9 5.7 3.8 7.2 0.1 2.6 2 0 0 2 2 2 0 EF hand DivIC PF04977.15 CBY11086.1 - 0.67 9.8 3.3 22 4.9 0.0 3.1 3 0 0 3 3 3 0 Septum formation initiator VIT1 PF01988.19 CBY11086.1 - 2.2 8.1 4.4 0.9 9.4 1.5 2.0 2 0 0 2 2 2 0 VIT family PID PF00640.23 CBY11087.1 - 1e-31 109.9 0.3 1.9e-31 108.9 0.3 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 CBY11087.1 - 2.2e-26 92.0 3.0 6.9e-12 45.5 0.0 3.0 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY11087.1 - 9.4e-15 54.2 0.3 2.4e-06 27.3 0.1 3.1 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 CBY11087.1 - 6.3e-06 26.4 0.1 0.0023 18.2 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 CBY11088.1 - 3.1e-48 164.5 1.8 4.6e-48 163.9 1.8 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY11088.1 - 2.5e-05 25.2 0.2 6e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain SOG2 PF10428.9 CBY11088.1 - 0.11 11.7 16.7 0.15 11.3 16.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PRCC PF10253.9 CBY11088.1 - 0.3 11.9 9.8 0.44 11.3 9.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SPX PF03105.19 CBY11088.1 - 0.81 9.5 5.3 1 9.2 5.3 1.1 1 0 0 1 1 1 0 SPX domain Sushi PF00084.20 CBY11088.1 - 5 7.8 9.1 0.64 10.7 2.6 2.6 1 1 1 2 2 2 0 Sushi repeat (SCR repeat) TFIIA PF03153.13 CBY11088.1 - 5.3 6.9 16.6 7.6 6.4 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypsin PF00089.26 CBY11089.1 - 1.3e-46 159.2 2.8 1.9e-46 158.7 2.8 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY11089.1 - 3.7e-07 31.2 0.6 3.7e-07 31.2 0.6 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF732 PF05305.14 CBY11089.1 - 0.049 14.0 0.0 0.049 14.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF732) DUF1986 PF09342.11 CBY11089.1 - 0.17 12.3 0.4 0.26 11.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Sushi PF00084.20 CBY11089.1 - 3.6 8.3 11.4 0.062 13.9 2.4 2.6 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Band_7 PF01145.25 CBY11090.1 - 1.7e-32 112.9 2.5 2.2e-32 112.5 2.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY11090.1 - 0.0011 18.7 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family MMADHC PF10229.9 CBY11093.1 - 2.1e-24 86.7 0.2 2.6e-24 86.4 0.2 1.3 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein GrpE PF01025.19 CBY11094.1 - 7.6e-35 120.0 10.8 1.6e-34 119.0 10.8 1.5 1 1 0 1 1 1 1 GrpE AAA_13 PF13166.6 CBY11094.1 - 0.15 10.7 8.7 0.18 10.4 8.7 1.1 1 0 0 1 1 1 0 AAA domain T2SSM PF04612.12 CBY11094.1 - 0.3 11.1 2.7 0.49 10.5 2.7 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Cauli_AT PF03233.13 CBY11094.1 - 0.67 9.9 5.3 1.3 8.9 5.3 1.4 1 0 0 1 1 1 0 Aphid transmission protein TMPIT PF07851.13 CBY11094.1 - 7.5 5.7 6.1 9.8 5.3 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein RRM_1 PF00076.22 CBY11095.1 - 1.4e-08 34.5 0.0 4.2e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY11095.1 - 0.023 14.8 0.3 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Myosin_head PF00063.21 CBY11096.1 - 6.8e-269 893.7 0.0 6.8e-269 893.7 0.0 2.8 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY11096.1 - 8.3e-131 437.8 241.2 1.1e-130 437.5 241.2 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY11096.1 - 1.9e-07 30.8 3.3 5.8e-07 29.2 3.3 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Cortex-I_coil PF09304.10 CBY11096.1 - 0.0028 17.8 8.4 0.0028 17.8 8.4 12.4 3 3 10 13 13 13 1 Cortexillin I, coiled coil IQ PF00612.27 CBY11096.1 - 0.0054 16.4 1.3 0.58 10.1 0.2 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY11096.1 - 0.11 12.7 0.0 0.11 12.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 CBY11096.1 - 0.59 10.5 0.0 0.59 10.5 0.0 4.8 4 2 0 4 4 4 0 AAA ATPase domain YqzL PF14006.6 CBY11096.1 - 1.3 9.4 5.1 5.4 7.4 0.0 5.1 2 1 0 2 2 2 0 YqzL-like protein Linker_histone PF00538.19 CBY11097.1 - 3.2e-18 65.8 0.1 3.2e-18 65.8 0.1 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 CBY11097.1 - 6.2e-05 23.2 70.7 0.0018 18.4 70.7 2.1 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 RT_RNaseH PF17917.1 CBY11099.1 - 1.4e-31 108.9 0.0 3.2e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY11099.1 - 1e-27 96.1 0.0 2.6e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY11099.1 - 1.5e-15 57.4 0.0 7.9e-15 55.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY11099.1 - 3.2e-12 46.4 1.3 6.8e-12 45.3 0.6 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 CBY11101.1 - 5.3e-13 49.0 0.1 1.8e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPEL PF02755.15 CBY11102.1 - 0.4 10.4 2.6 2 8.2 0.0 2.3 2 0 0 2 2 2 0 RPEL repeat RVT_1 PF00078.27 CBY11104.1 - 0.0046 16.5 0.1 1.5 8.3 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF327 PF03885.13 CBY11104.1 - 0.09 12.7 0.5 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF327) HYLS1_C PF15311.6 CBY11104.1 - 0.14 12.9 0.2 0.25 12.1 0.2 1.4 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus rve PF00665.26 CBY11105.1 - 0.0013 18.9 0.0 0.0039 17.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Pox_A21 PF05323.12 CBY11105.1 - 0.017 15.7 0.2 0.056 14.0 0.1 1.8 2 0 0 2 2 2 0 Poxvirus A21 Protein Integrase_H2C2 PF17921.1 CBY11106.1 - 1.2e-07 31.7 0.3 2.2e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H3C2 PF16721.5 CBY11106.1 - 0.025 14.9 0.1 0.04 14.3 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding rve PF00665.26 CBY11106.1 - 0.03 14.5 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 CBY11106.1 - 0.086 13.1 2.5 0.15 12.3 2.5 1.4 1 0 0 1 1 1 0 H2C2 zinc finger BAF1_ABF1 PF04684.13 CBY11107.1 - 0.026 13.6 0.1 0.03 13.4 0.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Phage_integrase PF00589.22 CBY11108.1 - 8.5e-10 38.7 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family SRP-alpha_N PF04086.13 CBY11108.1 - 8.2 6.2 16.2 16 5.3 16.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RVT_1 PF00078.27 CBY11109.1 - 7.1e-10 38.8 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC50 PF03381.15 CBY11111.1 - 1.3e-60 205.3 3.8 1.6e-32 113.2 0.7 2.1 1 1 1 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family HA PF03457.14 CBY11112.1 - 0.024 15.0 0.1 0.047 14.0 0.1 1.5 1 0 0 1 1 1 0 Helicase associated domain CR6_interact PF10147.9 CBY11112.1 - 0.88 9.2 9.5 6.9 6.3 4.1 2.2 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Glyco_hydro_cc PF11790.8 CBY11114.1 - 1e-22 80.9 0.5 1.6e-22 80.3 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Integrin_alpha2 PF08441.12 CBY11115.1 - 2.6e-09 36.5 14.9 1.5e-08 34.0 14.9 2.0 1 1 0 1 1 1 1 Integrin alpha VCBS PF13517.6 CBY11115.1 - 0.0018 18.8 0.2 0.064 13.9 0.0 2.6 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBY11115.1 - 0.017 15.2 7.0 0.051 13.7 1.9 3.7 4 0 0 4 4 4 0 FG-GAP repeat ASD2 PF08687.11 CBY11118.1 - 1.5e-24 87.1 4.9 1.5e-24 87.1 4.9 2.8 2 1 0 2 2 2 1 Apx/Shroom domain ASD2 GDC-P PF02347.16 CBY11118.1 - 0.15 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein SecG PF03840.14 CBY11119.1 - 0.46 10.6 3.5 2.8 8.1 3.4 2.2 1 1 0 1 1 1 0 Preprotein translocase SecG subunit GAS PF13851.6 CBY11121.1 - 0.021 14.1 6.3 0.034 13.5 6.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Galactosyl_T PF01762.21 CBY11121.1 - 0.051 13.4 0.6 0.14 12.0 0.0 1.8 2 1 0 2 2 2 0 Galactosyltransferase Lectin_C PF00059.21 CBY11122.1 - 1.3e-06 29.1 7.9 0.0012 19.6 0.3 3.7 4 0 0 4 4 4 2 Lectin C-type domain Xlink PF00193.17 CBY11122.1 - 0.033 14.6 5.5 3.3 8.2 0.1 3.9 3 1 1 4 4 4 0 Extracellular link domain UL45 PF05473.12 CBY11122.1 - 0.035 13.7 0.5 0.28 10.8 0.0 2.4 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like VWA PF00092.28 CBY11123.1 - 2.6e-16 60.4 0.3 4.3e-16 59.7 0.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CLCA PF08434.11 CBY11123.1 - 7.1e-14 51.8 0.1 1.2e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA_2 PF13519.6 CBY11123.1 - 5.2e-12 46.4 0.0 1.2e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY11123.1 - 0.00025 20.5 0.1 0.00042 19.8 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 CBY11123.1 - 0.0019 17.5 0.0 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) SNF PF00209.18 CBY11124.1 - 5.1e-201 668.9 28.6 5.8e-201 668.7 28.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family GHMP_kinases_N PF00288.26 CBY11124.1 - 0.046 14.0 0.0 0.33 11.2 0.0 2.5 1 1 0 1 1 1 0 GHMP kinases N terminal domain DUF3533 PF12051.8 CBY11124.1 - 0.2 10.5 7.5 0.43 9.4 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) FXa_inhibition PF14670.6 CBY11125.1 - 1.7e-06 28.2 5.2 3e-06 27.4 5.2 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY11125.1 - 0.0013 18.7 1.3 0.0029 17.5 1.3 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF PF00008.27 CBY11125.1 - 0.0027 18.0 3.2 0.0071 16.6 3.2 1.7 1 0 0 1 1 1 1 EGF-like domain TIL PF01826.17 CBY11125.1 - 0.051 13.8 4.7 0.088 13.1 4.7 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain EMC3_TMCO1 PF01956.16 CBY11125.1 - 0.081 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Tfb2_C PF18307.1 CBY11126.1 - 0.022 15.2 0.0 0.063 13.7 0.0 1.8 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain Glucos_trans_II PF14264.6 CBY11127.1 - 0.00015 21.2 3.8 0.00058 19.3 3.7 1.8 1 1 1 2 2 2 2 Glucosyl transferase GtrII Claudin_3 PF06653.11 CBY11127.1 - 0.031 14.2 13.7 0.2 11.6 13.3 2.2 1 1 1 2 2 2 0 Tight junction protein, Claudin-like Methyltrans_RNA PF04452.14 CBY11129.1 - 0.0033 16.8 1.8 0.042 13.2 0.1 2.7 2 1 1 3 3 3 1 RNA methyltransferase DUF2514 PF10721.9 CBY11129.1 - 0.39 10.7 5.0 1.7 8.7 5.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Ets PF00178.22 CBY11130.1 - 9.3e-36 122.2 0.2 1.6e-35 121.4 0.2 1.4 1 0 0 1 1 1 1 Ets-domain Peroxin-3 PF04882.12 CBY11130.1 - 1.7 7.6 6.9 2.4 7.1 6.9 1.2 1 0 0 1 1 1 0 Peroxin-3 Sugar_tr PF00083.24 CBY11131.1 - 2.5e-30 105.8 18.1 4.1e-30 105.1 18.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY11131.1 - 1.6e-22 80.0 19.6 1.6e-22 80.0 19.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3439 PF11921.8 CBY11131.1 - 0.012 15.6 1.7 0.034 14.1 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ctr PF04145.15 CBY11132.1 - 2.1e-18 67.3 14.0 3.1e-09 37.6 8.7 3.0 2 1 1 3 3 3 2 Ctr copper transporter family Voltage_CLC PF00654.20 CBY11132.1 - 0.0018 17.6 2.7 0.0018 17.6 2.7 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel Sigma_reg_N PF13800.6 CBY11132.1 - 0.075 13.3 6.1 2.2 8.6 0.1 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal TSP_1 PF00090.19 CBY11133.1 - 4.8e-79 260.4 215.4 6e-10 39.2 9.4 15.3 15 0 0 15 15 15 15 Thrombospondin type 1 domain Peptidase_M1 PF01433.20 CBY11135.1 - 1.3e-85 286.5 0.1 1.8e-85 286.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CBY11135.1 - 6.3e-59 200.1 1.3 9.4e-59 199.5 1.3 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CBY11135.1 - 1.1e-43 149.5 0.8 1.7e-43 149.0 0.8 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DHHC PF01529.20 CBY11136.1 - 2.8e-30 105.2 6.6 2.8e-30 105.2 6.6 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase SH3_2 PF07653.17 CBY11136.1 - 0.00073 19.2 0.0 0.0024 17.5 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CBY11136.1 - 0.0037 17.1 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY11136.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain PRiA4_ORF3 PF07929.11 CBY11136.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein ELYS PF13934.6 CBY11137.1 - 0.043 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex assembly UBA_4 PF14555.6 CBY11138.1 - 5.4e-07 29.3 0.0 6.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 CBY11138.1 - 0.0002 21.0 0.1 0.0004 20.0 0.0 1.6 2 0 0 2 2 2 1 CUE domain UBA PF00627.31 CBY11138.1 - 0.0089 15.9 0.8 0.0089 15.9 0.8 2.2 2 1 0 2 2 2 1 UBA/TS-N domain Sec7 PF01369.20 CBY11138.1 - 0.095 12.4 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Sec7 domain Pkinase PF00069.25 CBY11139.1 - 2.2e-05 24.0 0.7 8.4e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11139.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Attractin PF08037.11 CBY11139.1 - 0.32 11.0 2.2 0.85 9.7 2.2 1.7 1 0 0 1 1 1 0 Attractin family SKN1 PF03935.15 CBY11141.1 - 0.0015 17.0 0.2 0.0018 16.7 0.2 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF2569 PF10754.9 CBY11141.1 - 0.077 13.4 3.7 0.14 12.6 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) Sigma_reg_N PF13800.6 CBY11141.1 - 0.088 13.1 0.7 0.23 11.7 0.7 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal RRM_1 PF00076.22 CBY11142.1 - 1.1e-18 66.7 0.4 2.8e-18 65.5 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY11142.1 - 0.014 14.9 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPESP1 PF15754.5 CBY11144.1 - 0.24 10.5 3.8 0.31 10.2 3.1 1.5 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 Mucin PF01456.17 CBY11144.1 - 1.4 8.9 22.1 2.2 8.3 22.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 CBY11144.1 - 4.4 5.4 13.9 6 4.9 13.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 VLPT PF07122.11 CBY11145.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) DUF2069 PF09842.9 CBY11149.1 - 0.08 13.1 2.4 0.13 12.5 2.4 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2069) Glyco_hydro_31 PF01055.26 CBY11151.1 - 7.1e-50 170.5 1.8 1.1e-49 169.9 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CBY11151.1 - 0.037 14.4 0.8 0.13 12.6 0.1 2.3 3 0 0 3 3 3 0 Galactose mutarotase-like CBS PF00571.28 CBY11152.1 - 4.1e-25 88.0 0.2 7e-17 61.6 0.2 2.2 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 CBY11152.1 - 0.061 13.4 0.4 9.4 6.4 0.1 2.2 2 0 0 2 2 2 0 PRC-barrel domain EGF_CA PF07645.15 CBY11153.1 - 3.9e-19 68.6 23.0 3.5e-10 39.9 7.3 3.7 4 1 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.7 CBY11153.1 - 0.0011 18.9 4.3 0.0035 17.2 4.3 2.0 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY11153.1 - 0.15 12.3 20.7 0.2 11.9 7.8 3.1 3 0 0 3 3 3 0 EGF domain EGF_MSP1_1 PF12946.7 CBY11153.1 - 0.48 10.5 6.3 0.36 10.9 1.1 2.7 2 0 0 2 2 2 0 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY11153.1 - 7.4 7.0 13.6 0.86 9.9 6.5 2.6 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site PFU PF09070.11 CBY11154.1 - 0.034 14.4 0.2 0.048 13.9 0.2 1.2 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) zf-CCHC PF00098.23 CBY11155.1 - 7.8e-06 25.7 23.8 0.0001 22.2 3.1 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-C2H2_10 PF16588.5 CBY11155.1 - 0.0062 16.2 21.0 0.036 13.8 2.1 3.4 3 0 0 3 3 3 3 C2H2 zinc-finger zf-CCHC_6 PF15288.6 CBY11155.1 - 0.084 12.7 0.2 0.084 12.7 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-H2C2_2 PF13465.6 CBY11155.1 - 0.28 11.7 2.1 15 6.2 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-CCHC_4 PF14392.6 CBY11155.1 - 0.89 9.3 12.8 7.2 6.4 0.6 3.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.6 CBY11155.1 - 1 9.4 17.3 1.8 8.6 1.1 3.5 3 0 0 3 3 3 0 Zinc knuckle zf-Mss51 PF13824.6 CBY11155.1 - 2.9 8.1 5.1 12 6.0 1.4 2.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3716 PF12511.8 CBY11155.1 - 3.3 7.8 10.7 0.87 9.7 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Vfa1 PF08432.10 CBY11161.1 - 0.47 10.8 11.7 0.8 10.0 11.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Atg14 PF10186.9 CBY11161.1 - 1.1 8.2 5.7 1.8 7.6 5.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CREPT PF16566.5 CBY11161.1 - 6.1 7.0 9.7 13 6.0 8.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour zf-RING_2 PF13639.6 CBY11162.1 - 0.00032 21.0 13.7 0.00032 21.0 13.7 3.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CBY11162.1 - 0.0005 20.0 13.6 0.0005 20.0 13.6 3.1 2 1 1 3 3 3 1 zinc-RING finger domain DivIC PF04977.15 CBY11162.1 - 0.0055 16.5 11.6 0.36 10.6 2.7 2.9 3 0 0 3 3 3 2 Septum formation initiator zf-C3HC4_2 PF13923.6 CBY11162.1 - 0.011 15.6 13.4 0.011 15.6 13.4 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.11 CBY11162.1 - 0.015 14.2 11.4 0.032 13.1 9.7 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 CBY11162.1 - 0.021 15.1 12.9 0.19 12.0 13.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Csm1_N PF18504.1 CBY11162.1 - 0.038 14.3 7.3 0.62 10.4 0.2 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF3837 PF12939.7 CBY11162.1 - 0.076 13.4 0.8 0.076 13.4 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) PspA_IM30 PF04012.12 CBY11162.1 - 0.14 11.7 5.5 0.27 10.8 5.5 1.4 1 1 0 1 1 1 0 PspA/IM30 family zf-C3HC4 PF00097.25 CBY11162.1 - 0.17 11.8 31.4 0.063 13.2 13.9 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Syntaxin-6_N PF09177.11 CBY11162.1 - 0.22 12.1 5.6 1.1 9.9 5.6 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TSC22 PF01166.18 CBY11162.1 - 0.34 11.3 6.4 0.85 10.0 0.5 3.0 2 1 0 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 CBY11162.1 - 0.51 10.8 11.6 3.1 8.3 3.2 2.6 2 0 0 2 2 2 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 CBY11162.1 - 0.6 10.1 11.2 1.3 9.0 3.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 CBY11162.1 - 0.88 9.6 14.3 3e+02 1.4 0.0 3.8 2 1 1 3 3 3 0 Prefoldin subunit Spectrin PF00435.21 CBY11162.1 - 1 9.9 6.8 2.1 8.9 1.1 2.5 1 1 2 3 3 3 0 Spectrin repeat FlaC_arch PF05377.11 CBY11162.1 - 1.5 9.2 8.6 2.3 8.7 0.4 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 CBY11162.1 - 1.9 8.8 11.8 6.8 7.0 2.6 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 CBY11162.1 - 2.5 8.2 8.0 12 5.9 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 CBY11162.1 - 3.4 7.4 13.7 48 3.7 13.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 CBY11162.1 - 5.9 6.4 8.9 12 5.4 8.7 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Med28 PF11594.8 CBY11162.1 - 7 6.7 11.0 1.2 9.2 0.7 2.6 2 1 1 3 3 2 0 Mediator complex subunit 28 UPF0242 PF06785.11 CBY11162.1 - 7.1 6.7 16.0 2.7e+02 1.6 16.2 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 CBY11162.1 - 8.6 5.6 10.4 2.6 7.3 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) AAA_6 PF12774.7 CBY11163.1 - 5e-121 403.7 0.1 1.6e-82 277.1 0.0 3.6 3 1 1 4 4 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBY11163.1 - 9.6e-100 334.5 7.8 3.8e-73 246.9 0.9 3.4 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBY11163.1 - 1.2e-92 310.5 0.1 3.8e-92 308.8 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBY11163.1 - 1.2e-89 300.1 0.0 2.9e-89 298.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 CBY11163.1 - 5.4e-88 296.0 1.0 3.6e-51 174.5 0.8 2.8 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CBY11163.1 - 1.6e-83 279.2 1.2 1.6e-83 279.2 1.2 3.4 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CBY11163.1 - 8.5e-55 185.0 0.1 2.4e-54 183.6 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 CBY11163.1 - 2.2e-47 160.9 5.4 2.2e-41 141.4 0.1 5.2 4 1 1 5 5 5 3 P-loop containing dynein motor region Dynein_heavy PF03028.15 CBY11163.1 - 1.4e-43 147.8 0.1 3.9e-42 143.1 0.0 3.3 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBY11163.1 - 4.2e-40 137.8 6.6 8e-40 136.9 6.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 CBY11163.1 - 7.1e-20 71.1 0.0 5.9e-19 68.1 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CBY11163.1 - 1e-18 67.6 0.0 9.2e-07 28.9 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CBY11163.1 - 6.8e-07 29.4 3.0 1.9e-05 24.8 0.8 3.8 3 1 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CBY11163.1 - 0.00018 21.9 0.4 3.8 7.9 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) BRE1 PF08647.11 CBY11163.1 - 0.0016 18.4 0.7 0.0016 18.4 0.7 4.3 3 0 0 3 3 1 1 BRE1 E3 ubiquitin ligase AAA_18 PF13238.6 CBY11163.1 - 0.007 16.9 0.2 30 5.2 0.0 4.5 3 0 0 3 3 3 0 AAA domain ERK-JNK_inhib PF15002.6 CBY11163.1 - 0.019 14.7 1.0 0.48 10.1 0.1 3.0 3 0 0 3 3 2 0 ERK and JNK pathways, inhibitor AAA_16 PF13191.6 CBY11163.1 - 0.046 14.1 0.8 2.8 8.3 0.0 3.7 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 CBY11163.1 - 0.052 13.9 0.2 4.7 7.6 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_22 PF13401.6 CBY11163.1 - 0.061 13.6 0.2 9.9 6.4 0.0 3.6 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CBY11163.1 - 0.068 12.5 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family Rad17 PF03215.15 CBY11163.1 - 0.095 12.6 0.4 1.3 9.0 0.0 2.9 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_19 PF13245.6 CBY11163.1 - 0.22 11.8 1.5 7.7 6.8 0.1 3.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBY11163.1 - 0.26 11.0 1.5 13 5.4 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CBY11163.1 - 0.51 10.5 2.3 2.1 8.5 0.0 3.1 4 0 0 4 4 2 0 AAA domain DUF1664 PF07889.12 CBY11163.1 - 1.3 9.1 6.6 7.9 6.5 0.0 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) MMR_HSR1_C PF08438.10 CBY11163.1 - 6.9 7.3 6.8 2.8 8.5 2.0 3.0 2 0 0 2 2 1 0 GTPase of unknown function C-terminal DUF3584 PF12128.8 CBY11163.1 - 7.8 3.9 13.2 1.1 6.7 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) IL8 PF00048.20 CBY11164.1 - 0.0091 16.1 0.6 0.55 10.4 0.1 3.5 3 0 0 3 3 3 1 Small cytokines (intecrine/chemokine), interleukin-8 like Vac7 PF12751.7 CBY11165.1 - 0.078 12.4 0.3 0.093 12.2 0.3 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 rve PF00665.26 CBY11168.1 - 4.3e-07 30.1 0.0 8.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Dicty_REP PF05086.12 CBY11168.1 - 0.16 10.0 6.9 0.27 9.2 6.9 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 CBY11168.1 - 1.7 7.3 9.1 9.5 4.9 8.7 2.1 2 0 0 2 2 2 0 Presenilin TFIIA PF03153.13 CBY11168.1 - 7.4 6.5 27.0 11 5.9 27.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Uds1 PF15456.6 CBY11169.1 - 9.3 6.4 9.5 5.6 7.1 4.8 2.2 1 1 1 2 2 2 0 Up-regulated During Septation Pkinase PF00069.25 CBY11172.1 - 1.6e-43 149.0 0.7 3.2e-43 148.0 0.7 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11172.1 - 1.4e-32 113.1 0.1 2.1e-32 112.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY11172.1 - 1.7e-11 44.0 1.3 5e-11 42.5 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 CBY11172.1 - 0.00023 20.1 4.1 0.0031 16.4 0.0 2.8 3 0 0 3 3 3 2 Fungal protein kinase Kdo PF06293.14 CBY11172.1 - 0.0028 17.1 0.7 0.0043 16.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5082 PF16888.5 CBY11172.1 - 0.0077 16.5 4.2 0.0077 16.5 4.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) Phage_TAC_7 PF10109.9 CBY11172.1 - 0.012 15.7 0.0 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 APH PF01636.23 CBY11172.1 - 0.048 13.6 0.0 0.44 10.4 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family RBP_receptor PF14752.6 CBY11173.1 - 0.062 11.9 0.4 0.079 11.5 0.4 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor HemY_N PF07219.13 CBY11173.1 - 0.43 10.8 1.8 0.43 10.8 0.5 1.7 2 0 0 2 2 2 0 HemY protein N-terminus DUF5403 PF17395.2 CBY11174.1 - 0.082 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5403) Glycoprotein PF03409.15 CBY11175.1 - 0.037 12.9 7.4 0.037 12.9 7.4 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein RIFIN PF02009.16 CBY11175.1 - 0.043 13.7 0.4 0.048 13.6 0.4 1.1 1 0 0 1 1 1 0 Rifin DUF3439 PF11921.8 CBY11175.1 - 0.077 13.0 8.7 0.12 12.3 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4805 PF16063.5 CBY11175.1 - 0.24 10.7 3.8 0.29 10.4 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Dicty_REP PF05086.12 CBY11175.1 - 0.9 7.4 3.9 0.95 7.4 3.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoside_tran PF01733.18 CBY11179.1 - 0.0043 16.5 0.9 0.0043 16.5 0.9 1.8 2 0 0 2 2 2 1 Nucleoside transporter DUF3961 PF13106.6 CBY11179.1 - 0.084 12.5 3.8 7.8 6.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) 7tm_3 PF00003.22 CBY11180.1 - 7.2e-07 29.2 6.9 9.9e-07 28.7 6.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR TMEM70 PF06979.12 CBY11180.1 - 0.013 16.0 0.6 0.028 14.8 0.6 1.5 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex Lipase PF00151.19 CBY11181.1 - 1.7e-38 132.8 1.5 3.9e-38 131.6 1.5 1.6 1 1 0 1 1 1 1 Lipase DUF2974 PF11187.8 CBY11181.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 CBY11181.1 - 0.067 13.3 0.0 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Lipase PF00151.19 CBY11182.1 - 4.7e-54 184.0 3.4 7.2e-54 183.3 3.4 1.3 1 1 0 1 1 1 1 Lipase DUF900 PF05990.12 CBY11182.1 - 7.1e-06 25.7 0.3 1.3e-05 24.9 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 CBY11182.1 - 1.9e-05 24.3 0.1 2.9e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 CBY11182.1 - 0.00011 21.9 0.1 0.00053 19.6 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CBY11182.1 - 0.0041 17.0 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBY11182.1 - 0.0059 17.2 0.0 0.0091 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY11182.1 - 0.037 14.1 0.0 0.09 12.9 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 CBY11182.1 - 0.056 13.2 0.2 0.11 12.2 0.1 1.4 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 CBY11182.1 - 0.058 13.0 0.1 0.1 12.2 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold VirJ PF06057.11 CBY11182.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.13 CBY11182.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3763 PF12592.8 CBY11182.1 - 0.2 11.8 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) MIP PF00230.20 CBY11183.1 - 1.2e-22 80.8 16.7 2.3e-22 79.8 16.7 1.4 1 1 1 2 2 2 2 Major intrinsic protein Kelch_1 PF01344.25 CBY11184.1 - 7.7e-05 22.2 0.9 1.1 8.9 0.1 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CBY11184.1 - 0.00021 21.5 4.4 2.3 8.6 0.1 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY11184.1 - 0.0012 18.7 0.3 0.25 11.4 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY11184.1 - 0.026 14.5 0.5 11 6.2 0.1 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY11185.1 - 7.7e-05 22.2 0.9 1.1 8.9 0.1 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CBY11185.1 - 0.00021 21.4 4.4 2.3 8.6 0.1 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY11185.1 - 0.0012 18.7 0.3 0.25 11.4 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY11185.1 - 0.026 14.5 0.5 11 6.2 0.1 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain SH3_2 PF07653.17 CBY11187.1 - 1.6e-10 40.5 0.0 2.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY11187.1 - 2.6e-10 39.7 0.4 3.5e-10 39.3 0.4 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY11187.1 - 4.8e-10 39.1 0.1 6.3e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain Guanylate_cyc PF00211.20 CBY11188.1 - 3.5e-39 134.3 0.1 6.2e-39 133.5 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 CBY11188.1 - 0.0078 15.6 0.1 0.02 14.3 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11188.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Myosin_head PF00063.21 CBY11189.1 - 1e-274 913.0 0.0 1e-274 913.0 0.0 3.3 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY11189.1 - 2.9e-98 330.1 208.6 9.9e-92 308.4 183.8 3.5 1 1 2 3 3 3 2 Myosin tail AAA_22 PF13401.6 CBY11189.1 - 0.23 11.7 0.0 0.23 11.7 0.0 5.1 3 1 1 4 4 4 0 AAA domain AAA_16 PF13191.6 CBY11189.1 - 2 8.8 0.0 2 8.8 0.0 5.8 3 2 0 3 3 3 0 AAA ATPase domain DUF3800 PF12686.7 CBY11189.1 - 7 7.3 13.0 4.4e+03 -1.7 0.1 6.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Peptidase_C2 PF00648.21 CBY11190.1 - 4.6e-19 68.6 7.6 7e-19 68.0 7.6 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 CBY11191.1 - 4.2e-36 124.5 0.0 1.3e-35 122.9 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease MBDa PF16564.5 CBY11192.1 - 0.0089 16.2 9.0 9.7 6.5 0.1 4.0 3 0 0 3 3 3 3 p55-binding region of Methyl-CpG-binding domain proteins MBD HD PF01966.22 CBY11194.1 - 3.2e-10 40.3 0.9 1e-09 38.7 0.9 1.9 1 1 0 1 1 1 1 HD domain Acetyltransf_19 PF18015.1 CBY11194.1 - 0.08 13.2 0.2 0.25 11.6 0.2 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MIF4G PF02854.19 CBY11195.1 - 4.6e-12 46.0 12.4 4.6e-12 46.0 12.4 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 CBY11195.1 - 2.5e-09 37.1 0.4 1.1e-08 35.0 0.4 2.2 1 0 0 1 1 1 1 MA3 domain Ubiquitin_3 PF14836.6 CBY11195.1 - 1.8 8.6 5.7 3.6 7.7 1.1 3.3 3 0 0 3 3 3 0 Ubiquitin-like domain Adaptin_N PF01602.20 CBY11196.1 - 3.6e-102 342.6 10.4 5.4e-102 342.0 10.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CBY11196.1 - 1e-57 193.6 0.0 2.9e-57 192.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CBY11196.1 - 6.7e-56 188.1 0.1 6.7e-56 188.1 0.1 2.5 2 0 0 2 2 2 1 Coatomer beta C-terminal region Cnd1 PF12717.7 CBY11196.1 - 1.2e-11 45.0 9.7 9.6e-08 32.2 0.2 3.5 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY11196.1 - 9.3e-11 42.0 1.2 0.019 15.3 0.0 5.6 3 1 3 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 CBY11196.1 - 7.2e-08 32.8 0.9 0.39 11.3 0.0 5.0 4 1 0 4 4 4 3 HEAT-like repeat HEAT PF02985.22 CBY11196.1 - 7.4e-08 32.0 0.8 0.13 12.6 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat Coatomer_g_Cpla PF16381.5 CBY11196.1 - 0.00027 21.0 0.2 0.00087 19.4 0.0 1.9 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Arm PF00514.23 CBY11196.1 - 0.00097 19.1 1.3 0.52 10.4 0.1 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Vps16_N PF04841.13 CBY11196.1 - 0.0094 14.7 0.2 0.015 14.1 0.2 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region RNA_pol_Rpb1_5 PF04998.17 CBY11196.1 - 0.023 14.2 0.2 0.055 12.9 0.2 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Tho2 PF11262.8 CBY11196.1 - 0.062 12.5 1.1 1.1 8.4 0.0 2.8 3 1 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 eIF3_N PF09440.10 CBY11196.1 - 0.072 13.5 0.4 0.28 11.6 0.2 2.2 2 0 0 2 2 1 0 eIF3 subunit 6 N terminal domain WD40 PF00400.32 CBY11197.1 - 0.0046 17.8 3.2 0.032 15.1 0.3 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat WbqC PF08889.11 CBY11197.1 - 0.019 14.9 0.3 0.037 13.9 0.3 1.4 1 0 0 1 1 1 0 WbqC-like protein family DDDD PF10161.9 CBY11198.1 - 4.5e-15 55.2 0.0 5.6e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Putative mitochondrial precursor protein DDDD PF10161.9 CBY11200.1 - 4.5e-15 55.2 0.0 5.6e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Putative mitochondrial precursor protein Rsm22 PF09243.10 CBY11201.1 - 4.5e-28 98.3 0.0 1.4e-27 96.7 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CBY11201.1 - 2.4e-05 24.2 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY11201.1 - 0.00018 22.1 0.0 0.00061 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY11201.1 - 0.00055 19.8 0.0 0.0085 15.9 0.0 2.7 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY11201.1 - 0.0029 18.3 0.0 0.011 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY11201.1 - 0.022 15.4 0.0 0.07 13.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CBY11201.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain PDE4_UCR PF18100.1 CBY11202.1 - 0.075 13.7 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) MMR_HSR1 PF01926.23 CBY11203.1 - 7.9e-22 77.5 0.0 1.8e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY11203.1 - 8.2e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP1_OBG PF01018.22 CBY11203.1 - 6.7e-05 22.5 0.4 0.0012 18.5 0.4 2.2 1 1 0 1 1 1 1 GTP1/OBG Dynamin_N PF00350.23 CBY11203.1 - 0.0045 17.0 2.1 0.86 9.6 0.1 3.1 2 2 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 CBY11203.1 - 0.018 15.6 1.0 0.19 12.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBY11203.1 - 0.047 14.2 1.0 0.32 11.5 0.0 2.4 2 1 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 CBY11203.1 - 0.093 12.3 0.1 0.64 9.5 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 CBY11203.1 - 0.11 12.0 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY11203.1 - 0.12 12.3 0.0 22 4.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 CBY11203.1 - 0.14 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Atg14 PF10186.9 CBY11203.1 - 0.45 9.5 7.9 48 2.9 7.9 2.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 CBY11203.1 - 0.64 8.6 3.9 0.94 8.0 3.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 CBY11203.1 - 2.7 8.0 9.4 9.4 6.3 9.5 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMEM65 PF10507.9 CBY11204.1 - 3.5e-42 142.8 3.2 4.5e-42 142.4 3.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 65 TMEM131_like PF12371.8 CBY11205.1 - 2e-23 82.4 5.3 6.1e-21 74.5 0.2 4.4 5 0 0 5 5 5 2 Transmembrane protein 131-like ASH PF15780.5 CBY11205.1 - 4.2e-11 42.9 0.6 1.9e-08 34.4 0.1 4.2 5 0 0 5 5 5 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CBY11205.1 - 0.0025 17.6 2.3 0.44 10.4 0.2 3.6 3 0 0 3 3 3 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBY11205.1 - 0.0082 16.2 0.5 0.99 9.5 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1573) Aconitase PF00330.20 CBY11206.1 - 1.8e-142 475.6 0.0 2.3e-142 475.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CBY11206.1 - 4.5e-43 146.7 0.0 9e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CAP PF00188.26 CBY11207.1 - 1.1e-16 61.8 0.5 1.3e-16 61.6 0.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Phospholip_A2_1 PF00068.19 CBY11209.1 - 2.1e-13 50.7 8.5 2.1e-13 50.7 8.5 2.1 1 1 1 2 2 2 1 Phospholipase A2 Mon1 PF03164.14 CBY11210.1 - 7e-24 84.7 0.2 8.3e-24 84.4 0.2 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Frag1 PF10277.9 CBY11211.1 - 1.5e-21 76.9 23.3 1.9e-21 76.6 23.3 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family UEV PF05743.13 CBY11212.1 - 1e-18 67.3 0.0 1.7e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain zf-C3HC4_3 PF13920.6 CBY11212.1 - 1.2e-07 31.5 8.8 2.1e-07 30.7 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY11212.1 - 2.1e-06 27.4 7.7 4.1e-06 26.6 7.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY11212.1 - 7.4e-06 25.8 11.0 1.2e-05 25.2 11.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY11212.1 - 5.2e-05 23.5 9.5 9.4e-05 22.7 9.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY11212.1 - 0.0012 18.8 3.4 0.0035 17.3 1.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger UQ_con PF00179.26 CBY11212.1 - 0.0024 17.5 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C3HC4_2 PF13923.6 CBY11212.1 - 0.0057 16.5 9.7 0.011 15.6 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY11212.1 - 0.0087 15.9 7.1 0.022 14.6 7.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY11212.1 - 0.089 12.6 8.4 0.22 11.3 8.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 CBY11212.1 - 0.13 11.6 1.9 0.16 11.3 1.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1272 PF06906.11 CBY11212.1 - 0.33 11.1 4.4 0.58 10.3 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Gin PF10764.9 CBY11212.1 - 1.5 8.9 7.0 0.98 9.4 5.1 1.7 1 1 0 1 1 1 0 Inhibitor of sigma-G Gin MMR_HSR1 PF01926.23 CBY11213.1 - 7.1e-14 51.9 0.0 3e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY11213.1 - 5.3e-06 26.4 0.1 0.0018 18.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CBY11213.1 - 1.3e-05 24.8 0.1 2.9e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBY11213.1 - 2.9e-05 23.7 0.2 0.81 9.2 0.1 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CBY11213.1 - 3.8e-05 23.1 0.8 0.00012 21.5 0.1 2.2 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 CBY11213.1 - 0.0029 17.7 0.2 0.0029 17.7 0.2 3.4 3 1 1 4 4 4 1 Dynamin family PduV-EutP PF10662.9 CBY11213.1 - 0.027 14.2 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 CBY11213.1 - 0.031 14.0 0.0 0.031 14.0 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain Roc PF08477.13 CBY11213.1 - 0.037 14.2 0.1 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CBY11213.1 - 0.075 13.6 0.3 0.43 11.1 0.0 2.4 2 1 0 2 2 2 0 ABC transporter TcdB_N PF12918.7 CBY11214.1 - 0.00032 20.9 21.0 0.39 11.0 0.3 5.5 4 1 2 6 6 6 3 TcdB toxin N-terminal helical domain RPAP1_N PF08621.10 CBY11214.1 - 0.076 12.8 20.8 0.15 11.9 3.0 4.4 4 1 0 4 4 4 0 RPAP1-like, N-terminal NPV_P10 PF05531.12 CBY11214.1 - 0.1 13.1 3.8 11 6.6 0.0 4.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Cas_DxTHG PF09455.10 CBY11214.1 - 0.4 10.2 14.5 0.49 9.9 14.5 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Scm3 PF10384.9 CBY11214.1 - 0.6 9.9 7.3 0.47 10.2 1.8 3.0 2 0 0 2 2 2 0 Centromere protein Scm3 Bindin PF02084.15 CBY11214.1 - 0.99 9.6 6.2 0.16 12.2 1.7 2.0 1 1 1 2 2 2 0 Bindin ComX PF05952.12 CBY11214.1 - 1.2 9.2 6.2 37 4.4 0.0 4.1 4 1 1 5 5 5 0 Bacillus competence pheromone ComX TERF2_RBM PF16772.5 CBY11214.1 - 1.2 8.6 3.5 26 4.3 0.1 3.4 3 0 0 3 3 3 0 Telomeric repeat-binding factor 2 Rap1-binding motif RNA_pol_Rpb5_C PF01191.19 CBY11214.1 - 7.7 6.5 10.0 3.2 7.7 0.5 3.5 2 1 2 4 4 4 0 RNA polymerase Rpb5, C-terminal domain DUF1690 PF07956.11 CBY11214.1 - 9.1 6.7 32.2 0.75 10.2 13.5 3.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Ribosomal_L27_C PF18471.1 CBY11215.1 - 0.0042 16.6 1.0 0.0044 16.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain PhageMin_Tail PF10145.9 CBY11215.1 - 0.012 15.5 5.4 0.51 10.2 5.4 2.1 1 1 0 1 1 1 0 Phage-related minor tail protein DUF737 PF05300.11 CBY11215.1 - 0.014 15.7 2.3 0.016 15.6 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) SAPIS-gp6 PF16722.5 CBY11215.1 - 0.016 15.6 2.0 0.024 15.1 2.0 1.3 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Aminopep PF10023.9 CBY11215.1 - 0.026 13.9 0.2 0.028 13.8 0.2 1.2 1 0 0 1 1 1 0 Putative aminopeptidase DUF1104 PF06518.11 CBY11215.1 - 0.045 14.1 9.3 0.073 13.4 9.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) HSBP1 PF06825.12 CBY11215.1 - 0.083 12.8 4.7 0.98 9.3 4.6 2.5 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Rho_Binding PF08912.11 CBY11215.1 - 0.1 13.4 6.0 0.15 12.9 5.9 1.4 1 1 0 1 1 1 0 Rho Binding XhlA PF10779.9 CBY11215.1 - 0.7 10.1 4.2 1 9.6 4.2 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Abhydrolase_6 PF12697.7 CBY11216.1 - 2.1e-16 61.2 0.0 2.7e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY11216.1 - 3.4e-07 30.6 0.1 0.00029 21.0 0.0 2.9 3 0 0 3 3 3 2 Thioesterase domain Hydrolase_4 PF12146.8 CBY11216.1 - 3e-05 23.4 0.0 0.00014 21.2 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY11216.1 - 6.2e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1057 PF06342.12 CBY11216.1 - 0.0031 16.6 0.0 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 CBY11216.1 - 0.012 15.4 0.1 0.25 11.1 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CBY11216.1 - 0.023 14.3 0.0 0.051 13.1 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 CBY11216.1 - 0.054 12.4 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.13 CBY11216.1 - 0.087 12.7 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase PAF-AH_p_II PF03403.13 CBY11216.1 - 0.15 10.5 0.0 0.71 8.3 0.0 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipocalin_2 PF08212.12 CBY11217.1 - 4.2e-14 52.7 0.0 5.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY11217.1 - 0.00019 21.7 0.0 0.00027 21.2 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family EGF_CA PF07645.15 CBY11219.1 - 5.7e-20 71.2 32.1 1.9e-09 37.6 7.7 3.3 3 0 0 3 3 3 3 Calcium-binding EGF domain cEGF PF12662.7 CBY11219.1 - 6.4e-09 35.6 16.7 5.3e-06 26.2 0.6 3.8 3 1 0 3 3 3 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY11219.1 - 4e-08 33.3 28.9 0.0042 17.2 5.7 3.4 3 0 0 3 3 3 3 EGF domain hEGF PF12661.7 CBY11219.1 - 9.2e-06 26.1 26.3 0.0081 16.8 4.5 3.8 3 1 0 3 3 3 3 Human growth factor-like EGF EGF PF00008.27 CBY11219.1 - 5.7e-05 23.3 25.1 0.00081 19.6 6.5 3.4 3 0 0 3 3 3 2 EGF-like domain FXa_inhibition PF14670.6 CBY11219.1 - 7.2e-05 23.0 30.4 0.17 12.2 4.2 3.4 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site RANK_CRD_2 PF18278.1 CBY11219.1 - 0.0041 17.2 1.1 0.0041 17.2 1.1 3.4 4 0 0 4 4 4 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 TssO PF17561.2 CBY11219.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO vMSA PF00695.19 CBY11219.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Peptidase_S28 PF05577.12 CBY11221.1 - 6.3e-67 226.2 0.0 8.7e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 CBY11221.1 - 2.3e-05 23.3 0.0 3.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 CBY11221.1 - 3e-05 23.4 0.0 4.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBY11221.1 - 3.4e-05 24.6 0.2 0.00079 20.1 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBY11221.1 - 9e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY11221.1 - 0.025 14.0 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 CBY11221.1 - 0.14 11.3 0.3 0.21 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) zf-Tim10_DDP PF02953.15 CBY11222.1 - 3e-12 46.0 11.1 3e-12 46.0 11.1 1.9 1 1 1 2 2 2 1 Tim10/DDP family zinc finger DUF629 PF04780.12 CBY11222.1 - 0.019 13.5 5.2 0.019 13.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Aa_trans PF01490.18 CBY11223.1 - 2.4e-56 191.2 18.3 2.9e-56 190.9 18.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 CBY11223.1 - 8.3e-06 24.8 11.1 8.3e-06 24.8 11.1 2.6 2 1 0 2 2 2 1 Spore germination protein Trp_Tyr_perm PF03222.13 CBY11223.1 - 5.7e-05 22.3 21.3 0.00011 21.4 21.3 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF2448 PF10476.9 CBY11223.1 - 0.61 9.9 3.8 1.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function C-terminus (DUF2448) DEAD PF00270.29 CBY11224.1 - 2.5e-44 151.1 0.1 5.6e-44 150.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY11224.1 - 1.1e-22 80.4 0.0 6.3e-22 78.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBY11224.1 - 1.2e-13 51.0 0.1 3.1e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBY11224.1 - 5.5e-07 29.7 1.0 1.2e-06 28.6 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit KHA PF11834.8 CBY11225.1 - 0.016 15.3 0.2 0.032 14.3 0.2 1.5 1 1 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel SCP2 PF02036.17 CBY11226.1 - 5.3e-24 84.6 0.2 6.9e-24 84.3 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CBY11226.1 - 5.6e-06 26.6 0.1 7.1e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DnaJ PF00226.31 CBY11227.1 - 1e-11 44.8 0.2 1e-11 44.8 0.2 2.3 3 0 0 3 3 3 1 DnaJ domain DUF4337 PF14235.6 CBY11227.1 - 0.28 11.3 1.4 0.5 10.5 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) BILBO1_N PF18281.1 CBY11228.1 - 0.075 13.5 0.3 0.36 11.3 0.1 2.1 2 0 0 2 2 2 0 BILBO1 N-terminal domain Glycos_transf_1 PF00534.20 CBY11229.1 - 9.1e-12 44.8 0.0 2.2e-11 43.6 0.0 1.6 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBY11229.1 - 1.4e-09 38.4 0.0 5.5e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBY11229.1 - 3.3e-05 24.2 0.0 6.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY11229.1 - 0.0026 17.8 0.0 0.006 16.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CBY11229.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain ATP-synt_E_2 PF08112.11 CBY11229.1 - 0.14 12.4 0.7 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 ATP synthase epsilon subunit NEMP PF10225.9 CBY11230.1 - 0.00015 21.5 0.1 0.00031 20.5 0.0 1.5 2 0 0 2 2 2 1 NEMP family DUF2570 PF10828.8 CBY11230.1 - 0.01 15.7 0.4 0.015 15.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) NEMP PF10225.9 CBY11231.1 - 1.4e-29 103.5 26.5 4.2e-29 102.0 20.8 2.4 2 1 0 2 2 2 1 NEMP family DcuA_DcuB PF03605.14 CBY11231.1 - 0.055 12.4 3.9 0.15 10.9 3.9 1.7 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4133 PF13571.6 CBY11231.1 - 0.33 11.3 0.0 0.33 11.3 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4133) Rhodanese PF00581.20 CBY11234.1 - 1.7e-13 51.0 0.0 2.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain zf-C2H2 PF00096.26 CBY11236.1 - 4.1e-21 74.2 45.1 3.8e-06 27.1 0.1 7.5 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY11236.1 - 1.2e-14 53.7 40.3 0.0018 19.0 0.1 7.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY11236.1 - 1.8e-08 34.4 22.6 0.012 15.9 0.1 5.6 5 1 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY11236.1 - 1.7e-07 31.4 21.0 0.091 13.2 0.7 6.1 6 0 0 6 6 5 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBY11236.1 - 1.8e-06 28.1 33.7 0.0059 17.0 0.2 8.2 7 2 0 7 7 7 3 Zinc-finger double domain zf-Di19 PF05605.12 CBY11236.1 - 3.5e-06 27.2 18.5 0.033 14.5 0.4 5.3 5 0 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 CBY11236.1 - 0.0012 18.6 8.0 11 6.0 0.2 5.5 6 0 0 6 6 5 0 GAGA factor zf_UBZ PF18439.1 CBY11236.1 - 0.0015 18.1 22.0 0.28 10.8 0.8 6.1 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 CBY11236.1 - 0.019 15.1 19.9 3.1 8.0 0.5 5.6 5 1 0 5 5 5 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 CBY11236.1 - 0.036 14.2 18.1 3.8 7.7 0.1 5.4 4 2 1 5 5 5 0 Zinc ribbon domain zf-C2H2_3 PF13878.6 CBY11236.1 - 0.12 12.3 0.1 0.12 12.3 0.1 5.3 6 1 0 6 6 6 0 zinc-finger of acetyl-transferase ESCO Acetone_carb_G PF08882.11 CBY11236.1 - 0.12 12.6 6.4 0.14 12.4 0.0 3.5 3 1 1 4 4 3 0 Acetone carboxylase gamma subunit Rubredoxin PF00301.20 CBY11236.1 - 0.15 12.1 14.4 1.6 8.8 0.5 4.9 6 0 0 6 6 5 0 Rubredoxin YhfH PF14149.6 CBY11236.1 - 0.16 11.9 0.1 0.16 11.9 0.1 4.5 5 0 0 5 5 3 0 YhfH-like protein TF_Zn_Ribbon PF08271.12 CBY11236.1 - 0.36 10.4 10.4 24 4.5 0.0 5.2 5 0 0 5 5 5 0 TFIIB zinc-binding zf-ISL3 PF14690.6 CBY11236.1 - 0.39 11.4 4.4 6.7 7.5 0.2 3.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.7 CBY11236.1 - 0.48 10.5 17.0 2.5 8.2 1.3 4.2 3 1 0 3 3 3 0 Double zinc ribbon zf-C2H2_2 PF12756.7 CBY11236.1 - 0.54 10.6 26.0 0.18 12.1 0.9 5.3 3 1 1 5 5 5 0 C2H2 type zinc-finger (2 copies) DNA_ligase_ZBD PF03119.16 CBY11236.1 - 0.87 9.7 6.1 35 4.5 0.0 3.6 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-C4_Topoisom PF01396.19 CBY11236.1 - 1.8 8.4 6.0 18 5.2 0.3 3.7 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CBY11236.1 - 2.3 8.5 13.7 48 4.3 0.1 5.1 5 0 0 5 5 5 0 zinc-ribbon CxC7 PF18866.1 CBY11236.1 - 2.8 8.1 9.3 44 4.3 0.1 4.8 5 0 0 5 5 5 0 CxC7 like cysteine cluster associated with KDZ transposases Zn-C2H2_12 PF18112.1 CBY11236.1 - 2.9 8.5 21.6 2 9.0 0.1 6.6 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_15 PF17032.5 CBY11236.1 - 5.3 7.9 24.8 1.1 10.0 1.6 5.2 4 1 0 5 5 5 0 zinc-ribbon family C1_2 PF03107.16 CBY11236.1 - 5.7 7.3 18.7 3.5 8.0 0.1 5.7 5 1 1 6 6 6 0 C1 domain DUF1610 PF07754.11 CBY11236.1 - 5.9 6.9 10.1 5.2 7.1 1.8 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.6 CBY11236.1 - 8.8 5.9 21.1 7.7 6.1 0.4 6.0 6 0 0 6 6 6 0 zinc-ribbon domain Kelch_6 PF13964.6 CBY11237.1 - 6.9e-07 29.3 0.1 0.025 14.9 0.0 3.8 2 1 1 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY11237.1 - 0.00024 21.0 0.2 0.01 15.8 0.1 3.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 CBY11237.1 - 0.00039 20.6 0.1 0.025 14.8 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY11237.1 - 0.028 14.4 7.3 12 6.0 0.0 5.2 5 1 0 5 5 5 0 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY11237.1 - 0.05 13.2 0.2 5.4 6.7 0.1 3.3 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 CBY11237.1 - 0.052 13.5 2.6 0.38 10.8 0.0 3.8 5 1 0 5 5 5 0 Kelch motif Sulfotransfer_2 PF03567.14 CBY11238.1 - 8.9e-08 32.3 0.0 1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CBY11239.1 - 3.2e-06 27.2 0.0 6.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Kelch_5 PF13854.6 CBY11240.1 - 4.3e-12 45.7 17.8 0.0019 18.2 0.0 6.1 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.25 CBY11240.1 - 0.00074 19.1 27.2 3.8 7.2 0.1 8.0 10 0 0 10 10 10 5 Kelch motif Kelch_2 PF07646.15 CBY11240.1 - 0.032 14.2 25.5 2.3 8.3 0.1 7.6 8 0 0 8 8 8 0 Kelch motif DUF3390 PF11870.8 CBY11240.1 - 0.066 13.6 0.2 42 4.6 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3390) Tim44 PF04280.15 CBY11240.1 - 0.34 11.0 1.3 29 4.8 0.1 2.3 2 0 0 2 2 2 0 Tim44-like domain Pkinase_Tyr PF07714.17 CBY11241.1 - 6.1e-18 65.0 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY11241.1 - 5.8e-13 48.8 0.0 8.4e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY11241.1 - 0.0023 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Guanylate_cyc PF00211.20 CBY11242.1 - 2.4e-30 105.5 0.0 3.3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Annexin PF00191.20 CBY11243.1 - 8.6e-61 201.9 6.9 4.7e-23 81.0 0.1 4.1 4 0 0 4 4 4 4 Annexin EcoEI_R_C PF08463.10 CBY11243.1 - 0.022 14.9 0.1 0.041 14.0 0.1 1.6 1 1 0 1 1 1 0 EcoEI R protein C-terminal DnaJ PF00226.31 CBY11244.1 - 3.4e-13 49.5 0.3 1e-12 48.0 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain TSP_1 PF00090.19 CBY11245.1 - 6.4e-05 23.1 4.5 6.4e-05 23.1 4.5 1.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain RhoGAP PF00620.27 CBY11246.1 - 3.6e-29 101.5 0.0 7.3e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 CBY11246.1 - 5.8e-05 22.9 8.3 0.00011 22.0 8.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) bZIP_2 PF07716.15 CBY11246.1 - 0.077 13.1 0.4 0.077 13.1 0.4 2.0 2 0 0 2 2 2 0 Basic region leucine zipper PHD_4 PF16866.5 CBY11246.1 - 4.1 7.6 7.8 45 4.2 7.8 2.5 1 1 0 1 1 1 0 PHD-finger Dimer_Tnp_hAT PF05699.14 CBY11247.1 - 5.5e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AAA PF00004.29 CBY11248.1 - 3.4e-37 127.8 0.0 5.4e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBY11248.1 - 9.4e-06 25.5 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBY11248.1 - 1.2e-05 25.6 1.1 0.0031 17.8 0.3 2.7 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CBY11248.1 - 6.4e-05 23.1 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ATPase PF06745.13 CBY11248.1 - 6.5e-05 22.4 0.1 0.04 13.3 0.0 2.2 1 1 1 2 2 2 2 KaiC AAA_33 PF13671.6 CBY11248.1 - 7.8e-05 22.9 0.0 0.00012 22.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBY11248.1 - 0.00014 21.9 0.1 0.0023 17.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CBY11248.1 - 0.00031 20.5 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CBY11248.1 - 0.00095 19.6 0.1 0.024 15.0 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 CBY11248.1 - 0.0012 18.2 0.0 0.0035 16.6 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain DUF2075 PF09848.9 CBY11248.1 - 0.0012 18.2 0.0 0.094 11.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 CBY11248.1 - 0.0017 18.3 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CBY11248.1 - 0.0036 17.7 0.1 0.0098 16.3 0.1 1.9 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CBY11248.1 - 0.0037 17.3 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBY11248.1 - 0.0039 16.6 0.0 0.0097 15.3 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CBY11248.1 - 0.011 15.7 0.0 0.57 10.1 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_7 PF12775.7 CBY11248.1 - 0.019 14.5 0.1 0.06 12.8 0.1 1.8 1 1 1 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 CBY11248.1 - 0.034 13.9 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBY11248.1 - 0.045 13.5 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 CBY11248.1 - 0.045 14.3 0.5 0.12 12.9 0.5 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CBY11248.1 - 0.06 12.8 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 CBY11248.1 - 0.065 13.0 0.1 5.1 6.8 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 CBY11248.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 CBY11248.1 - 0.14 12.4 0.1 19 5.5 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_3 PF07726.11 CBY11248.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBY11248.1 - 0.19 11.4 0.1 0.58 9.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain Nup_retrotrp_bd PF10599.9 CBY11250.1 - 0.017 15.8 2.0 0.019 15.6 0.7 1.6 2 0 0 2 2 2 0 Retro-transposon transporting motif Sugar_tr PF00083.24 CBY11252.1 - 5e-23 81.7 21.7 6.8e-23 81.2 21.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY11252.1 - 3.6e-19 68.9 24.3 6.5e-16 58.2 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MSP1a PF11670.8 CBY11252.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.0 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) DUF4017 PF13209.6 CBY11253.1 - 0.012 15.6 1.5 0.026 14.5 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) YtpI PF14007.6 CBY11253.1 - 0.023 14.8 6.2 0.1 12.8 3.2 2.4 2 1 0 2 2 2 0 YtpI-like protein GWT1 PF06423.12 CBY11253.1 - 0.071 13.2 7.4 0.25 11.5 4.9 2.0 1 1 1 2 2 2 0 GWT1 COX1 PF00115.20 CBY11253.1 - 0.23 10.2 7.5 0.17 10.7 6.0 1.4 1 1 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Cation_ATPase_C PF00689.21 CBY11253.1 - 0.36 10.5 8.0 0.54 9.9 8.0 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus PID PF00640.23 CBY11254.1 - 2.4e-07 30.8 0.0 2.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Meth_synt_2 PF01717.18 CBY11254.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain LSM PF01423.22 CBY11255.1 - 5.1e-16 58.1 0.0 7.3e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain GRP PF07172.11 CBY11255.1 - 0.00097 19.8 11.5 0.0015 19.2 11.5 1.3 1 0 0 1 1 1 1 Glycine rich protein family SM-ATX PF14438.6 CBY11255.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain RT_RNaseH PF17917.1 CBY11257.1 - 1.1e-29 102.7 0.0 2.2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY11257.1 - 1.1e-28 99.2 0.0 1.9e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY11257.1 - 4.2e-14 52.8 0.1 4.7e-13 49.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CBY11257.1 - 6.6e-07 29.1 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY11257.1 - 2.8e-06 27.3 0.0 7.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_thumb PF06817.14 CBY11257.1 - 0.023 14.5 0.1 0.096 12.5 0.1 1.9 2 0 0 2 2 2 0 Reverse transcriptase thumb domain Prot_ATP_OB_N PF17758.1 CBY11257.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain LKAAEAR PF15478.6 CBY11259.1 - 1.1e-10 41.9 7.3 1.5e-10 41.5 7.3 1.2 1 0 0 1 1 1 1 Family of unknown function with LKAAEAR motif DUF1974 PF09317.11 CBY11259.1 - 0.65 9.5 5.6 0.77 9.3 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Peptidase_S46 PF10459.9 CBY11259.1 - 9.7 4.7 8.5 12 4.3 8.5 1.0 1 0 0 1 1 1 0 Peptidase S46 Reprolysin PF01421.19 CBY11260.1 - 3.1e-30 105.6 0.1 3.1e-30 105.6 0.1 2.4 3 0 0 3 3 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 CBY11260.1 - 1.5e-17 64.0 13.3 1.5e-17 64.0 13.3 3.8 3 1 0 3 3 1 1 ADAM cysteine-rich Disintegrin PF00200.23 CBY11260.1 - 2e-15 57.3 29.6 2e-15 57.3 29.6 4.9 5 2 1 6 6 4 1 Disintegrin Reprolysin_5 PF13688.6 CBY11260.1 - 1.4e-13 51.5 0.0 3.6e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY11260.1 - 4e-13 50.0 0.1 8.9e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CBY11260.1 - 1.3e-07 31.7 0.0 3.6e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY11260.1 - 2.4e-06 27.4 0.1 4.6e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CBY11260.1 - 0.00046 20.1 0.0 0.00079 19.3 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.13 CBY11260.1 - 0.01 15.7 0.0 0.037 13.9 0.0 1.9 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.9 CBY11260.1 - 0.045 12.7 0.1 0.11 11.5 0.1 1.6 1 0 0 1 1 1 0 Peptidase M66 DUF3810 PF12725.7 CBY11260.1 - 0.099 12.0 0.1 4.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) CSN8_PSD8_EIF3K PF10075.9 CBY11261.1 - 4.2e-32 111.1 1.1 7.6e-32 110.3 1.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CBY11261.1 - 8.1e-07 28.7 2.1 1.2e-06 28.1 2.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family DUF5320 PF17253.2 CBY11262.1 - 0.045 14.8 0.3 0.085 13.9 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) TF_AP-2 PF03299.14 CBY11263.1 - 6.7e-85 284.0 0.0 8.3e-85 283.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor AP-2 ADPRTs_Tse2 PF18648.1 CBY11265.1 - 0.069 13.2 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins Pkinase PF00069.25 CBY11266.1 - 3.3e-43 147.9 0.1 4.6e-43 147.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11266.1 - 1e-29 103.6 0.1 1.3e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY11266.1 - 4e-13 49.3 0.0 5.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY11266.1 - 0.0016 17.3 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY11266.1 - 0.05 12.9 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY11266.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CBY11267.1 - 1.8e-44 152.1 0.9 2.9e-44 151.4 0.9 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11267.1 - 9e-31 107.1 0.3 9e-31 107.1 0.3 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY11267.1 - 3.7e-11 42.9 1.4 3.8e-11 42.8 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Gal_Lectin PF02140.18 CBY11267.1 - 9.2e-07 29.2 5.3 9.2e-07 29.2 5.3 1.9 2 0 0 2 2 2 1 Galactose binding lectin domain Pkinase_fungal PF17667.1 CBY11267.1 - 0.0034 16.2 0.0 0.0034 16.2 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase TPR_MLP1_2 PF07926.12 CBY11267.1 - 0.0056 16.7 7.8 0.0056 16.7 7.8 1.6 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Kdo PF06293.14 CBY11267.1 - 0.01 15.2 0.0 0.062 12.6 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lectin_N PF03954.14 CBY11267.1 - 0.028 14.2 0.1 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Ly49 PF08391.10 CBY11267.1 - 0.074 13.4 6.2 0.24 11.8 6.2 1.8 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region APH PF01636.23 CBY11267.1 - 0.1 12.5 0.1 0.44 10.4 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_1 PF00583.25 CBY11268.1 - 5.6e-08 33.0 0.1 1.3e-07 31.8 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY11268.1 - 2.4e-07 30.7 0.4 6.5e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY11268.1 - 0.00029 20.9 0.0 0.045 13.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY11268.1 - 0.0003 20.8 0.1 0.00071 19.7 0.1 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase RecX PF02631.16 CBY11268.1 - 0.00037 21.0 0.2 0.081 13.4 0.0 2.2 2 0 0 2 2 2 1 RecX family Acetyltransf_3 PF13302.7 CBY11268.1 - 0.00048 20.8 0.1 0.0083 16.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY11268.1 - 0.0019 18.6 0.0 0.004 17.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY11268.1 - 0.084 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ins_allergen_rp PF06757.13 CBY11268.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Peptidase_C1 PF00112.23 CBY11269.1 - 1.2e-72 244.6 0.7 1.6e-72 244.1 0.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY11269.1 - 5.3e-11 42.8 3.7 5.3e-11 42.8 3.7 2.1 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY11269.1 - 4.3e-06 25.8 0.7 0.025 13.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family IBD PF10416.9 CBY11269.1 - 0.041 13.9 0.2 0.041 13.9 0.2 2.8 3 0 0 3 3 3 0 Transcription-initiator DNA-binding domain IBD OST-HTH PF12872.7 CBY11269.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Pkinase PF00069.25 CBY11270.1 - 2.4e-64 217.2 0.0 3.1e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11270.1 - 3.1e-32 111.9 0.0 4.4e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 CBY11270.1 - 1.5e-12 47.2 0.2 3.9e-12 45.9 0.2 1.6 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 CBY11270.1 - 2.1e-05 24.0 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY11270.1 - 0.017 14.1 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CBY11270.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBY11270.1 - 0.027 14.1 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 CBY11270.1 - 0.036 14.8 1.5 0.036 14.8 1.5 2.4 3 1 0 3 3 3 0 Protein kinase C terminal domain APH PF01636.23 CBY11270.1 - 0.072 13.0 0.1 0.15 11.9 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family CaiF_GrlA PF07180.11 CBY11270.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator SCAMP PF04144.13 CBY11271.1 - 1.9e-62 210.7 13.9 2.3e-62 210.4 13.9 1.1 1 0 0 1 1 1 1 SCAMP family FERM_F1 PF18379.1 CBY11271.1 - 0.33 11.0 3.0 0.82 9.7 3.0 1.6 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain Pedibin PF08182.11 CBY11271.1 - 0.51 10.2 5.5 0.9 9.4 5.5 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family RsgA_GTPase PF03193.16 CBY11272.1 - 0.00014 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase GBP PF02263.19 CBY11272.1 - 0.0026 17.1 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 CBY11272.1 - 0.0054 16.8 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EutC PF05985.11 CBY11272.1 - 0.034 13.5 0.1 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) AAA_16 PF13191.6 CBY11272.1 - 0.037 14.4 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CBY11272.1 - 0.09 13.3 0.2 0.23 12.0 0.0 1.7 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 CBY11272.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Membralin PF09746.9 CBY11274.1 - 1.6e-64 218.3 6.4 9.6e-52 176.3 3.0 2.7 1 1 1 2 2 2 2 Tumour-associated protein MAP7 PF05672.11 CBY11275.1 - 0.0024 17.6 87.9 0.0024 17.6 87.9 4.2 4 1 0 4 4 4 2 MAP7 (E-MAP-115) family DSPn PF14671.6 CBY11276.1 - 8e-62 207.8 0.2 4.4e-61 205.4 0.1 2.0 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CBY11276.1 - 1.1e-11 44.6 0.0 2.6e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY11276.1 - 0.00022 21.4 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBY11276.1 - 0.0013 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY11276.1 - 0.038 14.0 0.2 0.064 13.2 0.2 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Amidohydro_1 PF01979.20 CBY11277.1 - 7.7e-11 41.9 0.1 1.2e-10 41.3 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBY11277.1 - 2.3e-10 40.6 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Glyco_hydro_99 PF16317.5 CBY11277.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 ARGLU PF15346.6 CBY11278.1 - 0.029 14.2 4.2 0.053 13.4 4.2 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF3275 PF11679.8 CBY11278.1 - 0.094 12.7 0.4 3.4 7.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Sulfotransfer_1 PF00685.27 CBY11281.1 - 9e-14 51.6 0.1 2e-12 47.1 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY11281.1 - 2.6e-10 41.1 0.0 3.2e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family DUF3504 PF12012.8 CBY11281.1 - 0.025 14.5 0.3 0.048 13.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Pkinase PF00069.25 CBY11282.1 - 3.8e-06 26.5 0.0 3.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11282.1 - 0.14 11.4 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase EF-hand_6 PF13405.6 CBY11283.1 - 9.8e-12 43.8 0.3 1.1e-06 28.1 0.4 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY11283.1 - 8.5e-11 40.6 2.5 7.2e-06 25.2 0.4 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY11283.1 - 1.5e-09 38.2 0.1 0.00035 21.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY11283.1 - 1.1e-06 28.3 2.7 0.029 14.2 0.2 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY11283.1 - 1.2e-05 24.6 2.0 4.1e-05 22.9 1.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 CBY11283.1 - 0.009 15.9 0.2 0.061 13.3 0.0 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Sec2p PF06428.11 CBY11284.1 - 0.024 14.6 0.9 0.024 14.6 0.9 4.3 4 1 0 4 4 4 0 GDP/GTP exchange factor Sec2p Phage_TAC_4 PF08748.11 CBY11284.1 - 0.028 14.8 0.2 0.091 13.1 0.2 1.9 1 0 0 1 1 1 0 Phage tail assembly chaperone Peptidase_C1 PF00112.23 CBY11285.1 - 2.9e-78 262.9 3.4 4.3e-78 262.3 3.4 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY11285.1 - 5.5e-10 39.5 1.9 9e-10 38.8 1.9 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY11285.1 - 0.0021 16.9 1.1 0.15 10.8 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family EF-hand_1 PF00036.32 CBY11286.1 - 2.1e-13 48.8 11.4 1.2e-07 30.8 0.6 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CBY11286.1 - 8.2e-12 45.4 3.2 3.6e-11 43.3 2.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY11286.1 - 2e-11 42.9 8.4 1e-07 31.3 1.2 2.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY11286.1 - 7.6e-11 41.0 3.7 3.6e-06 26.2 0.6 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY11286.1 - 1.3e-07 31.3 9.8 0.00018 21.3 2.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY11286.1 - 3e-05 24.3 0.2 3.6e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CBY11286.1 - 0.00012 22.3 2.6 0.00052 20.3 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CBY11286.1 - 0.0023 17.8 3.3 0.036 14.0 0.5 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Glyco_transf_10 PF00852.19 CBY11287.1 - 3.1e-50 170.3 0.0 6.4e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY11287.1 - 5.5e-15 55.8 0.1 1.3e-14 54.5 0.1 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal LIM PF00412.22 CBY11288.1 - 6.5e-42 141.6 72.0 3e-12 46.6 6.0 5.4 5 1 0 5 5 5 5 LIM domain Lipoprotein_15 PF03640.15 CBY11288.1 - 0.13 11.8 0.2 0.29 10.7 0.2 1.6 1 0 0 1 1 1 0 Secreted repeat of unknown function Adaptin_N PF01602.20 CBY11289.1 - 0.00075 18.2 0.1 0.0016 17.1 0.1 1.5 1 0 0 1 1 1 1 Adaptin N terminal region CRM1_repeat PF18777.1 CBY11289.1 - 0.23 11.0 0.2 0.23 11.0 0.2 2.0 2 0 0 2 2 2 0 Chromosome region maintenance or exportin repeat Urm1 PF09138.11 CBY11291.1 - 5.1e-24 84.5 0.0 5.6e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CBY11291.1 - 0.0026 18.4 0.0 0.0034 18.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family Ribosomal_S6e PF01092.19 CBY11292.1 - 1.1e-56 190.2 0.1 1.1e-56 190.2 0.1 2.1 2 1 0 2 2 2 1 Ribosomal protein S6e DUF755 PF05501.11 CBY11292.1 - 0.0036 17.6 13.2 0.0065 16.7 13.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF755) ATPase-cat_bd PF12156.8 CBY11292.1 - 0.13 13.1 0.9 0.36 11.6 0.0 2.1 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase DUF2992 PF11208.8 CBY11292.1 - 0.21 11.8 14.7 0.42 10.9 14.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Protocadherin PF08374.11 CBY11292.1 - 1.4 8.8 8.1 2.2 8.2 8.1 1.4 1 0 0 1 1 1 0 Protocadherin Ribosomal_L5e PF17144.4 CBY11294.1 - 6.9e-80 266.8 0.4 6.9e-80 266.8 0.4 2.1 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CBY11294.1 - 3.9e-35 120.7 5.8 3.9e-35 120.7 5.8 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thg1C PF14413.6 CBY11294.1 - 0.025 14.7 2.3 0.96 9.6 1.5 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain Ribosomal_60s PF00428.19 CBY11295.1 - 5.9e-23 81.3 9.0 6.9e-23 81.1 9.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF108 PF01958.18 CBY11295.1 - 0.097 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF108 SprT-like PF10263.9 CBY11296.1 - 3e-30 104.4 0.1 6.1e-30 103.4 0.1 1.5 2 0 0 2 2 2 1 SprT-like family Glyco_tranf_2_4 PF13704.6 CBY11298.1 - 1.6e-07 31.7 1.5 9.6e-07 29.2 1.5 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Mitoc_L55 PF09776.9 CBY11299.1 - 2.6e-14 52.9 0.2 3.5e-14 52.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 AIP3 PF03915.13 CBY11301.1 - 0.012 14.8 10.8 0.015 14.4 10.8 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 YscO PF07321.12 CBY11301.1 - 0.017 15.1 5.3 3.8 7.5 0.5 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO DUF2800 PF10926.8 CBY11301.1 - 0.042 13.1 2.3 0.049 12.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Cep57_CLD_2 PF14197.6 CBY11301.1 - 0.042 13.9 10.9 0.19 11.8 2.2 2.8 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 GAS PF13851.6 CBY11301.1 - 0.25 10.7 16.8 0.37 10.1 16.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Nucleoside_tran PF01733.18 CBY11301.1 - 0.3 10.4 2.9 0.47 9.8 2.9 1.3 1 0 0 1 1 1 0 Nucleoside transporter Rootletin PF15035.6 CBY11301.1 - 0.84 9.6 15.0 0.45 10.5 10.9 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 CBY11301.1 - 1.1 9.3 17.7 1.5 8.9 16.6 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.8 CBY11301.1 - 2.2 7.9 7.6 1.9 8.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) TPR_MLP1_2 PF07926.12 CBY11301.1 - 6.1 6.9 16.2 0.16 12.0 5.5 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-C2H2 PF00096.26 CBY11302.1 - 3.4e-19 68.1 23.0 2e-06 27.9 0.6 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY11302.1 - 4.6e-12 45.8 19.1 1.5e-07 31.5 0.2 5.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY11302.1 - 1.4e-08 34.9 24.6 0.015 16.1 0.4 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY11302.1 - 0.00048 20.3 9.4 0.84 10.0 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CBY11302.1 - 0.0042 17.4 6.5 5.3 7.4 0.1 3.5 2 1 0 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 CBY11302.1 - 0.024 14.4 10.9 1.7 8.5 1.1 4.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 CBY11302.1 - 0.029 14.5 6.7 3.8 7.6 0.1 3.3 1 1 1 3 3 3 0 Aberrant zinc-finger zf-LYAR PF08790.11 CBY11302.1 - 0.045 13.7 1.3 0.27 11.2 0.1 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 CBY11302.1 - 0.26 11.4 4.5 4.3 7.5 0.3 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 CBY11302.1 - 1.2 9.6 11.1 2.9 8.4 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.21 CBY11302.1 - 3.2 8.1 7.9 1.6 9.0 1.0 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Hid1 PF12722.7 CBY11304.1 - 3.6 5.6 18.1 4.3 5.4 18.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 CBY11304.1 - 5.5 5.7 15.3 6.5 5.5 15.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 CBY11304.1 - 5.6 5.6 19.8 10 4.8 19.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PA26 PF04636.13 CBY11304.1 - 7.6 5.3 13.9 11 4.8 13.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ARID PF01388.21 CBY11305.1 - 1.9e-17 63.7 0.0 2.7e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CybS PF05328.12 CBY11305.1 - 0.085 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit eRF1_1 PF03463.15 CBY11305.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 1 Myotub-related PF06602.14 CBY11307.1 - 6.6e-78 262.1 0.0 9.9e-78 261.5 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FDX-ACB PF03147.14 CBY11308.1 - 0.069 13.6 0.0 0.38 11.2 0.0 2.3 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain WD40 PF00400.32 CBY11309.1 - 1.6e-08 35.0 0.0 0.017 15.9 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY11309.1 - 9.6e-06 25.8 0.0 0.084 13.2 0.0 4.6 3 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY11309.1 - 0.028 13.7 0.1 22 4.2 0.0 3.3 3 1 0 3 3 3 0 WD40-like domain Kelch_2 PF07646.15 CBY11309.1 - 0.042 13.8 0.3 20 5.4 0.0 3.7 4 0 0 4 4 4 0 Kelch motif CPSF_A PF03178.15 CBY11309.1 - 0.046 13.0 0.0 0.088 12.1 0.0 1.6 1 1 0 1 1 1 0 CPSF A subunit region DUF5122 PF17164.4 CBY11309.1 - 0.11 12.8 0.1 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Cadherin_C PF01049.17 CBY11310.1 - 1.9e-19 70.4 0.2 3.2e-19 69.7 0.2 1.3 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin PF00028.17 CBY11310.1 - 2e-08 34.6 0.0 5.1e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Cadherin domain Adeno_E3_CR2 PF02439.15 CBY11310.1 - 4.4 7.2 5.6 7.6 6.4 5.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cadherin PF00028.17 CBY11311.1 - 1.3e-11 44.8 0.1 2.6e-09 37.4 0.1 3.3 3 0 0 3 3 3 1 Cadherin domain Ribosomal_L27e PF01777.18 CBY11311.1 - 0.056 13.8 1.4 13 6.2 1.6 2.5 2 0 0 2 2 2 0 Ribosomal L27e protein family Ion_trans PF00520.31 CBY11312.1 - 5.6e-09 35.6 10.4 5.6e-09 35.6 10.4 3.0 3 0 0 3 3 3 1 Ion transport protein Galactosyl_T PF01762.21 CBY11313.1 - 2.6e-25 89.4 0.0 5.8e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase Chitin_bind_1 PF00187.19 CBY11313.1 - 0.027 15.0 21.2 0.12 12.9 20.2 2.4 1 1 1 2 2 2 0 Chitin recognition protein Peptidase_M1_N PF17900.1 CBY11314.1 - 7.4e-25 88.2 0.2 1e-24 87.7 0.2 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain NuiA PF07924.11 CBY11315.1 - 0.39 11.1 2.9 2.9 8.3 0.1 3.0 3 0 0 3 3 3 0 Nuclease A inhibitor-like protein DIOX_N PF14226.6 CBY11316.1 - 3.8e-05 24.4 0.1 5.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HEPN_LA2681 PF18733.1 CBY11316.1 - 0.00047 19.5 1.0 0.00082 18.7 1.0 1.5 1 1 0 1 1 1 1 LA2681-like HEPN Peptidase_S9 PF00326.21 CBY11317.1 - 1.4e-40 139.1 1.0 2.3e-40 138.3 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CBY11317.1 - 0.043 14.4 0.0 0.084 13.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CBY11317.1 - 0.05 13.4 0.1 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 CBY11317.1 - 0.053 13.2 0.2 0.15 11.6 0.2 1.7 1 1 0 1 1 1 0 Putative esterase DUF3271 PF11675.8 CBY11318.1 - 0.059 12.6 0.7 0.074 12.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Lectin_C PF00059.21 CBY11319.1 - 0.024 15.3 0.5 1.1 10.1 0.2 2.4 2 0 0 2 2 2 0 Lectin C-type domain Cellulose_synt PF03552.14 CBY11320.1 - 0.017 13.7 1.1 0.023 13.2 1.1 1.1 1 0 0 1 1 1 0 Cellulose synthase FXa_inhibition PF14670.6 CBY11321.1 - 0.00011 22.4 8.2 0.0004 20.6 8.2 2.1 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Kelch_6 PF13964.6 CBY11322.1 - 0.00069 19.8 11.5 13 6.3 0.0 6.3 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 CBY11322.1 - 0.0017 18.2 13.7 1.6 8.8 0.0 6.0 5 1 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 CBY11322.1 - 0.19 11.8 18.3 6.3 6.9 0.1 6.1 7 0 0 7 7 7 0 Kelch motif Kelch_1 PF01344.25 CBY11322.1 - 0.44 10.2 13.1 7.4 6.2 0.4 5.5 6 0 0 6 6 6 0 Kelch motif cNMP_binding PF00027.29 CBY11325.1 - 2.2e-09 37.2 0.1 5.9e-06 26.3 0.0 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Phage_T4_Ndd PF06591.11 CBY11325.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Tropomyosin PF00261.20 CBY11326.1 - 5.9e-50 169.8 53.4 1.5e-48 165.3 44.5 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 CBY11326.1 - 6.3e-13 49.1 51.1 1.7e-12 47.7 27.1 3.2 2 1 1 3 3 3 1 Tropomyosin like Laminin_II PF06009.12 CBY11326.1 - 0.00039 20.4 27.7 0.37 10.8 2.3 4.2 1 1 3 4 4 4 4 Laminin Domain II ATG16 PF08614.11 CBY11326.1 - 0.0039 17.4 39.7 0.19 11.9 12.3 2.8 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CBY11326.1 - 0.0063 15.4 42.2 0.12 11.3 17.8 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein MscS_porin PF12795.7 CBY11326.1 - 0.044 13.3 37.2 0.027 14.0 22.1 3.0 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 CBY11326.1 - 0.22 11.6 25.0 0.23 11.5 5.2 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 CBY11326.1 - 0.39 11.1 33.6 0.079 13.3 5.1 4.3 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) AAA_13 PF13166.6 CBY11326.1 - 0.63 8.6 38.2 1.1 7.8 24.1 2.1 1 1 1 2 2 2 0 AAA domain Glyco_hydro_4 PF02056.16 CBY11326.1 - 0.74 9.3 4.3 0.28 10.7 1.0 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase PspA_IM30 PF04012.12 CBY11326.1 - 0.81 9.2 37.3 0.69 9.4 6.3 3.4 1 1 2 3 3 2 0 PspA/IM30 family WXG100 PF06013.12 CBY11326.1 - 1.2 9.4 18.5 1.1 9.5 0.2 4.7 3 2 0 4 4 4 0 Proteins of 100 residues with WXG SH3BP5 PF05276.14 CBY11326.1 - 1.3 8.7 30.5 0.48 10.2 17.0 3.0 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) DUF745 PF05335.13 CBY11326.1 - 1.6 8.5 27.9 9 6.0 0.3 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF745) ERM PF00769.19 CBY11326.1 - 2.3 8.0 49.2 9 6.0 1.6 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Noelin-1 PF12308.8 CBY11326.1 - 2.4 8.2 14.0 0.28 11.2 0.7 4.0 2 2 1 4 4 4 0 Neurogenesis glycoprotein Fez1 PF06818.15 CBY11326.1 - 2.6 8.5 38.1 0.9 10.0 16.7 2.4 1 1 1 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 CBY11326.1 - 3.4 7.7 45.0 0.11 12.5 8.4 3.8 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 CBY11326.1 - 3.7 7.9 48.8 0.72 10.2 10.6 3.3 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 CBY11326.1 - 3.9 6.7 37.9 0.079 12.3 5.3 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 CBY11326.1 - 4.3 4.7 38.9 6.4 4.1 38.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.14 CBY11326.1 - 7.5 6.3 40.1 1.8 8.4 8.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) XhlA PF10779.9 CBY11326.1 - 8 6.7 33.1 2 8.6 0.4 5.5 2 2 4 6 6 6 0 Haemolysin XhlA zf-B_box PF00643.24 CBY11327.1 - 2.1e-08 34.2 7.0 3.1e-08 33.6 7.0 1.3 1 0 0 1 1 1 1 B-box zinc finger FYVE PF01363.21 CBY11327.1 - 0.0018 18.4 0.3 0.003 17.7 0.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger MFS_Mycoplasma PF07672.13 CBY11327.1 - 0.0036 16.6 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Mycoplasma MFS transporter Fez1 PF06818.15 CBY11327.1 - 0.045 14.2 7.2 0.075 13.5 7.1 1.5 1 1 0 1 1 1 0 Fez1 DUF948 PF06103.11 CBY11327.1 - 0.066 13.5 2.2 1.9 8.8 0.8 2.8 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2968 PF11180.8 CBY11327.1 - 0.088 12.4 2.1 1.7 8.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF5320 PF17253.2 CBY11327.1 - 0.1 13.7 2.9 0.76 10.9 1.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Prefoldin PF02996.17 CBY11327.1 - 0.22 11.5 0.3 0.22 11.5 0.3 3.0 2 1 1 3 3 3 0 Prefoldin subunit DUF3232 PF11554.8 CBY11327.1 - 0.3 11.5 4.7 1 9.7 4.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3232) Cob_adeno_trans PF01923.18 CBY11327.1 - 0.33 11.1 3.1 0.16 12.1 0.9 1.6 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF1043 PF06295.12 CBY11327.1 - 1.6 8.7 5.3 0.63 10.1 0.8 2.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1043) Prefoldin_2 PF01920.20 CBY11327.1 - 1.7 8.7 15.6 0.66 10.0 6.7 3.0 2 1 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 CBY11327.1 - 1.8 8.6 5.1 16 5.5 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 CBY11327.1 - 3.6 6.8 7.5 0.64 9.3 2.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Osmo_CC PF08946.10 CBY11327.1 - 5.1 7.4 10.0 8.3 6.8 0.5 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil UPF0184 PF03670.13 CBY11327.1 - 5.4 7.5 12.7 0.22 11.9 5.2 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) DivIC PF04977.15 CBY11327.1 - 6 6.7 8.4 6 6.7 0.2 2.5 2 1 0 2 2 2 0 Septum formation initiator Fzo_mitofusin PF04799.13 CBY11327.1 - 6.2 6.3 8.0 18 4.9 0.0 2.8 2 1 1 3 3 3 0 fzo-like conserved region Exog_C PF18026.1 CBY11327.1 - 7.1 6.8 7.3 26 5.0 0.0 3.2 3 0 0 3 3 2 0 Endo/exonuclease (EXOG) C-terminal domain MIEAP PF16026.5 CBY11327.1 - 7.6 6.7 6.9 14 5.8 0.1 2.5 2 1 1 3 3 2 0 Mitochondria-eating protein Kelch_5 PF13854.6 CBY11329.1 - 6.9e-08 32.3 2.8 0.04 13.9 0.0 5.0 5 0 0 5 5 5 2 Kelch motif EGF PF00008.27 CBY11329.1 - 6.2e-07 29.6 4.5 1.6e-06 28.3 4.5 1.8 1 0 0 1 1 1 1 EGF-like domain Kelch_4 PF13418.6 CBY11329.1 - 0.00065 19.6 4.1 0.44 10.6 0.0 4.6 4 0 0 4 4 4 1 Galactose oxidase, central domain EGF_2 PF07974.13 CBY11329.1 - 0.0029 17.9 7.8 0.0073 16.6 7.8 1.7 1 0 0 1 1 1 1 EGF-like domain Kelch_6 PF13964.6 CBY11329.1 - 0.011 16.0 13.2 3.2 8.2 0.0 5.9 6 2 1 7 7 7 0 Kelch motif hEGF PF12661.7 CBY11329.1 - 0.042 14.5 4.1 0.15 12.7 4.1 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF MetOD2 PF18548.1 CBY11329.1 - 0.16 12.1 2.0 8 6.6 1.5 2.3 2 0 0 2 2 2 0 Metanogen output domain 2 EGF_CA PF07645.15 CBY11329.1 - 0.75 10.1 7.3 2.3 8.5 7.3 1.8 1 0 0 1 1 1 0 Calcium-binding EGF domain Kelch_1 PF01344.25 CBY11329.1 - 3.6 7.3 5.8 1.5 8.5 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Tropomyosin PF00261.20 CBY11330.1 - 1.2e-49 168.8 59.1 1.8e-48 165.0 45.3 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 CBY11330.1 - 5.9e-12 45.9 49.7 1.6e-11 44.6 25.7 3.2 2 1 1 3 3 3 1 Tropomyosin like Laminin_II PF06009.12 CBY11330.1 - 0.00044 20.3 27.4 0.39 10.7 2.9 4.2 1 1 3 4 4 4 4 Laminin Domain II Spc7 PF08317.11 CBY11330.1 - 0.0071 15.3 41.8 0.16 10.8 17.9 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein ATG16 PF08614.11 CBY11330.1 - 0.0084 16.4 39.0 0.26 11.5 10.7 2.8 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 CBY11330.1 - 0.37 11.2 36.6 0.48 10.8 15.4 2.2 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 CBY11330.1 - 0.39 10.8 24.9 0.42 10.7 5.6 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 CBY11330.1 - 0.69 10.3 32.8 0.86 10.0 1.7 4.4 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) WXG100 PF06013.12 CBY11330.1 - 0.86 9.9 17.6 1.4 9.2 0.1 4.7 3 2 0 4 4 4 0 Proteins of 100 residues with WXG PspA_IM30 PF04012.12 CBY11330.1 - 1.6 8.3 36.6 0.66 9.5 6.3 3.5 1 1 0 2 2 2 0 PspA/IM30 family Noelin-1 PF12308.8 CBY11330.1 - 2 8.5 13.2 0.25 11.3 0.8 3.8 2 2 2 4 4 4 0 Neurogenesis glycoprotein GPS2_interact PF15784.5 CBY11330.1 - 2.6 8.5 20.6 0.15 12.6 2.3 3.9 1 1 3 4 4 4 0 G-protein pathway suppressor 2-interacting domain TPR_MLP1_2 PF07926.12 CBY11330.1 - 2.9 8.0 43.5 0.12 12.5 8.5 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 CBY11330.1 - 3.2 6.3 38.7 4.3 5.9 25.9 2.1 1 1 1 2 2 2 0 AAA domain DUF3450 PF11932.8 CBY11330.1 - 3.7 6.8 36.5 0.084 12.2 5.4 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 CBY11330.1 - 3.9 4.9 37.4 5.7 4.3 37.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF745 PF05335.13 CBY11330.1 - 4.3 7.0 27.9 9.4 5.9 0.4 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF745) ERM PF00769.19 CBY11330.1 - 5.1 6.8 48.5 0.52 10.1 5.7 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 CBY11330.1 - 7.2 6.8 44.1 0.42 10.8 10.1 3.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 zf-B_box PF00643.24 CBY11331.1 - 2.2e-08 34.1 7.0 3.8e-08 33.4 7.0 1.4 1 0 0 1 1 1 1 B-box zinc finger FYVE PF01363.21 CBY11331.1 - 0.0021 18.2 0.4 0.0039 17.3 0.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger MFS_Mycoplasma PF07672.13 CBY11331.1 - 0.0045 16.3 0.0 0.0062 15.8 0.0 1.1 1 0 0 1 1 1 1 Mycoplasma MFS transporter Fez1 PF06818.15 CBY11331.1 - 0.043 14.3 6.6 0.073 13.5 6.5 1.5 1 1 0 1 1 1 0 Fez1 DUF948 PF06103.11 CBY11331.1 - 0.054 13.8 1.2 1.5 9.2 0.2 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2968 PF11180.8 CBY11331.1 - 0.11 12.1 1.9 2.2 7.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF5320 PF17253.2 CBY11331.1 - 0.18 12.9 3.1 1.1 10.4 1.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Prefoldin PF02996.17 CBY11331.1 - 0.34 10.8 11.0 0.26 11.2 0.3 2.9 2 1 1 3 3 3 0 Prefoldin subunit Exog_C PF18026.1 CBY11331.1 - 0.41 10.7 2.7 31 4.7 0.0 3.1 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain IBR PF01485.21 CBY11331.1 - 0.44 10.8 4.9 1.2 9.4 4.9 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Cob_adeno_trans PF01923.18 CBY11331.1 - 0.48 10.6 3.1 0.23 11.6 0.9 1.6 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF1043 PF06295.12 CBY11331.1 - 1.9 8.5 4.9 1.1 9.3 1.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) MIEAP PF16026.5 CBY11331.1 - 2.1 8.5 4.9 13 5.9 0.1 2.4 1 1 1 2 2 2 0 Mitochondria-eating protein DUF1664 PF07889.12 CBY11331.1 - 2.2 8.3 4.6 20 5.3 1.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 CBY11331.1 - 2.2 7.5 6.3 0.36 10.1 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 CBY11331.1 - 2.2 8.3 15.3 0.71 9.9 6.5 2.9 2 1 0 2 2 2 0 Prefoldin subunit DivIC PF04977.15 CBY11331.1 - 3.5 7.5 7.0 7.4 6.4 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator Osmo_CC PF08946.10 CBY11331.1 - 7.5 6.9 10.0 9.9 6.5 0.5 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil UPF0184 PF03670.13 CBY11331.1 - 8.2 6.9 12.8 0.28 11.6 5.2 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Fzo_mitofusin PF04799.13 CBY11331.1 - 8.9 5.8 7.7 22 4.6 0.0 2.8 2 1 1 3 3 3 0 fzo-like conserved region zf-MIZ PF02891.20 CBY11332.1 - 2.1e-06 27.4 3.8 4.4e-06 26.3 3.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBY11332.1 - 0.0092 15.8 0.9 0.037 13.8 0.9 2.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 CBY11332.1 - 0.54 10.1 4.3 1.1 9.1 4.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY11332.1 - 0.95 9.8 4.8 2.3 8.6 4.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 CBY11332.1 - 7 6.6 6.2 1.7 8.6 2.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cohesin_load PF10345.9 CBY11333.1 - 5.1e-14 51.7 14.8 6.2e-12 44.8 8.5 2.3 2 0 0 2 2 2 2 Cohesin loading factor TPR_2 PF07719.17 CBY11333.1 - 0.011 15.8 0.0 0.37 11.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RNase_PH PF01138.21 CBY11334.1 - 9.5e-26 90.9 0.0 1.6e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBY11334.1 - 2.1e-06 27.7 0.0 4.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Peptidase_C12 PF01088.21 CBY11335.1 - 1.1e-65 221.3 0.0 1.8e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CBY11335.1 - 1.9e-17 62.9 0.2 1.9e-17 62.9 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Laminin_EGF PF00053.24 CBY11336.1 - 5.7e-10 39.2 42.0 0.00064 19.8 12.9 3.9 1 1 2 3 3 3 3 Laminin EGF domain Cytochrom_C_2 PF01322.20 CBY11336.1 - 0.046 14.6 5.3 2.6 8.9 0.1 4.2 2 2 1 4 4 4 0 Cytochrome C' Mss4 PF04421.13 CBY11336.1 - 0.1 12.8 1.9 0.68 10.1 0.4 2.9 2 0 0 2 2 2 0 Mss4 protein PTPS PF01242.19 CBY11336.1 - 0.54 10.2 4.0 9.3 6.2 0.2 2.7 1 1 1 2 2 2 0 6-pyruvoyl tetrahydropterin synthase WGG PF10273.9 CBY11336.1 - 5.8 7.7 8.2 0.48 11.1 0.9 2.9 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 DUF4618 PF15397.6 CBY11336.1 - 6 6.2 18.9 0.067 12.6 3.9 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) Peptidase_C12 PF01088.21 CBY11337.1 - 1.1e-65 221.3 0.0 1.8e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CBY11337.1 - 1.3e-17 63.4 0.3 1.3e-17 63.4 0.3 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases RNase_PH PF01138.21 CBY11338.1 - 8.7e-26 91.0 0.0 1.5e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBY11338.1 - 2e-06 27.7 0.0 4.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cohesin_load PF10345.9 CBY11339.1 - 5.8e-07 28.4 13.7 1.2e-06 27.3 7.9 2.3 1 1 1 2 2 2 2 Cohesin loading factor zf-MIZ PF02891.20 CBY11340.1 - 6.5e-06 25.8 4.5 1.4e-05 24.8 4.5 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBY11340.1 - 0.0029 17.4 1.0 0.013 15.3 1.0 2.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-BED PF02892.15 CBY11340.1 - 0.085 12.9 1.4 1.7 8.8 0.5 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C3HC4_2 PF13923.6 CBY11340.1 - 0.7 9.8 4.2 1.5 8.7 4.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY11340.1 - 2 8.8 4.7 4.5 7.7 4.7 1.6 1 0 0 1 1 1 0 Ring finger domain S-methyl_trans PF02574.16 CBY11341.1 - 2.4e-28 99.7 0.0 2.9e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Tropomyosin_1 PF12718.7 CBY11342.1 - 2.7e-11 43.8 14.2 3.2e-11 43.6 14.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 CBY11342.1 - 1.8e-09 37.3 16.0 1.2e-07 31.4 7.2 2.0 1 1 1 2 2 2 2 Tropomyosin GPS2_interact PF15784.5 CBY11342.1 - 0.00019 21.8 6.8 0.023 15.1 1.7 2.3 1 1 1 2 2 2 2 G-protein pathway suppressor 2-interacting domain MscS_porin PF12795.7 CBY11342.1 - 0.00024 20.7 4.8 0.00032 20.3 4.8 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain SOGA PF11365.8 CBY11342.1 - 0.00098 20.2 2.7 0.0015 19.6 2.7 1.3 1 0 0 1 1 1 1 Protein SOGA PspA_IM30 PF04012.12 CBY11342.1 - 0.0013 18.3 10.3 0.0098 15.5 2.2 2.0 1 1 1 2 2 2 2 PspA/IM30 family ATG16 PF08614.11 CBY11342.1 - 0.0033 17.7 9.0 0.004 17.4 9.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 CBY11342.1 - 0.0038 17.6 9.8 0.049 14.0 5.7 2.1 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) DUF724 PF05266.14 CBY11342.1 - 0.0052 16.6 10.2 0.16 11.8 7.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF724) Spc7 PF08317.11 CBY11342.1 - 0.0089 14.9 11.4 0.011 14.6 11.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 CBY11342.1 - 0.0099 14.6 7.7 0.01 14.5 7.7 1.0 1 0 0 1 1 1 1 AAA domain IFT57 PF10498.9 CBY11342.1 - 0.017 14.1 6.4 0.021 13.8 6.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CorA PF01544.18 CBY11342.1 - 0.02 14.2 4.4 0.022 14.1 4.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 CBY11342.1 - 0.021 15.1 7.3 6.6 7.1 5.2 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2968 PF11180.8 CBY11342.1 - 0.022 14.4 6.6 0.028 14.0 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) MCPsignal PF00015.21 CBY11342.1 - 0.033 14.0 5.6 0.044 13.6 5.6 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4407 PF14362.6 CBY11342.1 - 0.035 13.5 7.0 0.048 13.0 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CBY11342.1 - 0.038 14.0 6.2 0.065 13.3 5.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.11 CBY11342.1 - 0.038 14.1 6.4 0.1 12.7 0.8 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.6 CBY11342.1 - 0.045 14.2 2.6 0.045 14.2 2.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BRE1 PF08647.11 CBY11342.1 - 0.049 13.7 9.8 0.021 14.9 7.0 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 CBY11342.1 - 0.063 13.9 5.9 1.6 9.4 0.9 2.3 1 1 1 2 2 2 0 SlyX APG6_N PF17675.1 CBY11342.1 - 0.067 13.7 13.4 0.38 11.3 1.5 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Laminin_II PF06009.12 CBY11342.1 - 0.072 13.1 5.9 0.096 12.7 5.9 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF1192 PF06698.11 CBY11342.1 - 0.073 13.1 7.2 0.53 10.4 1.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) WXG100 PF06013.12 CBY11342.1 - 0.074 13.3 0.6 0.26 11.5 0.1 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG ERM PF00769.19 CBY11342.1 - 0.08 12.8 10.4 0.1 12.4 10.4 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MAD PF05557.13 CBY11342.1 - 0.099 11.0 10.4 0.17 10.2 10.4 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein DHR10 PF18595.1 CBY11342.1 - 0.1 12.7 12.8 0.46 10.6 12.8 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Plk4_PB2 PF18409.1 CBY11342.1 - 0.11 13.2 4.6 2.6 8.8 0.5 2.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF3584 PF12128.8 CBY11342.1 - 0.13 9.8 9.3 0.14 9.6 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 CBY11342.1 - 0.15 11.4 11.8 0.18 11.2 11.8 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 CBY11342.1 - 0.16 12.2 11.7 0.2 11.8 11.7 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CLZ PF16526.5 CBY11342.1 - 0.16 12.3 10.5 0.91 9.9 4.9 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels V_ATPase_I PF01496.19 CBY11342.1 - 0.17 9.8 5.3 0.18 9.7 5.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CBY11342.1 - 0.17 11.1 4.2 0.23 10.7 4.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein End3 PF12761.7 CBY11342.1 - 0.23 11.6 7.2 0.45 10.7 1.7 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 LUC7 PF03194.15 CBY11342.1 - 0.24 11.0 7.4 0.63 9.7 7.4 1.6 1 1 0 1 1 1 0 LUC7 N_terminus DUF3450 PF11932.8 CBY11342.1 - 0.26 10.6 8.9 3.1 7.0 8.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ApoO PF09769.9 CBY11342.1 - 0.28 11.1 0.9 10 6.1 0.3 2.1 1 1 0 2 2 2 0 Apolipoprotein O ADIP PF11559.8 CBY11342.1 - 0.29 11.2 11.5 0.29 11.2 4.1 2.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 CBY11342.1 - 0.33 11.0 13.4 0.78 9.8 2.6 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Tup_N PF08581.10 CBY11342.1 - 0.35 11.2 7.1 0.22 11.9 3.1 2.1 1 1 1 2 2 2 0 Tup N-terminal DUF16 PF01519.16 CBY11342.1 - 0.38 11.3 8.1 3.4 8.2 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 CALCOCO1 PF07888.11 CBY11342.1 - 0.4 9.5 11.9 0.46 9.3 11.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Val_tRNA-synt_C PF10458.9 CBY11342.1 - 0.46 10.8 6.0 3.6 7.9 5.4 2.5 1 1 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Uds1 PF15456.6 CBY11342.1 - 0.53 10.5 8.2 0.98 9.6 1.8 2.2 1 1 1 2 2 2 0 Up-regulated During Septation Atg14 PF10186.9 CBY11342.1 - 0.67 9.0 6.3 0.79 8.7 6.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 CBY11342.1 - 0.69 9.3 11.3 1.1 8.7 11.3 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 KxDL PF10241.9 CBY11342.1 - 0.7 10.2 4.9 1.7 9.0 1.0 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein DUF812 PF05667.11 CBY11342.1 - 0.79 8.5 11.6 0.84 8.4 11.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Ax_dynein_light PF10211.9 CBY11342.1 - 0.82 9.6 12.0 1.3 8.9 4.7 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Uso1_p115_C PF04871.13 CBY11342.1 - 0.9 9.9 10.1 6.5 7.1 10.1 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PEP-utilisers_N PF05524.13 CBY11342.1 - 0.91 9.7 6.9 0.38 10.9 3.5 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Fib_alpha PF08702.10 CBY11342.1 - 0.94 9.7 6.5 3.2 7.9 6.5 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Trimer_CC PF08954.11 CBY11342.1 - 1 9.0 5.6 14 5.3 0.7 2.8 2 1 0 2 2 2 0 Trimerisation motif Fzo_mitofusin PF04799.13 CBY11342.1 - 1.1 8.8 6.1 0.58 9.7 2.3 1.9 1 1 1 2 2 2 0 fzo-like conserved region TRAF_BIRC3_bd PF16673.5 CBY11342.1 - 1.2 8.9 8.1 2.2 8.2 5.0 2.7 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Spc24 PF08286.11 CBY11342.1 - 1.4 9.2 9.8 7.6 6.8 2.4 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-Q PF13094.6 CBY11342.1 - 1.8 8.8 9.7 6.6 6.9 2.0 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Swi5 PF07061.11 CBY11342.1 - 2.2 8.4 9.3 6 7.0 3.5 2.5 1 1 1 2 2 2 0 Swi5 DUF4140 PF13600.6 CBY11342.1 - 2.4 8.7 9.2 11 6.5 2.7 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 CBY11342.1 - 2.4 8.6 6.5 3.5 8.1 1.1 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 CBY11342.1 - 2.9 8.3 10.3 11 6.5 0.8 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) XhlA PF10779.9 CBY11342.1 - 3 8.1 13.3 4.1 7.7 2.9 2.7 1 1 3 4 4 4 0 Haemolysin XhlA LMBR1 PF04791.16 CBY11342.1 - 4.6 6.0 6.5 5.3 5.8 6.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4164 PF13747.6 CBY11342.1 - 4.8 7.5 12.9 18 5.7 4.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.6 CBY11342.1 - 7.2 6.8 10.8 0.43 10.7 2.1 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF1329 PF07044.11 CBY11343.1 - 0.08 12.2 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) GGACT PF06094.12 CBY11344.1 - 1.8e-12 47.9 0.0 2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 CBY11344.1 - 0.00023 21.5 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family IIGP PF05049.13 CBY11345.1 - 1.3e-41 143.0 1.4 1.8e-41 142.5 1.4 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 CBY11345.1 - 0.013 15.6 0.0 0.04 14.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF659 PF04937.15 CBY11345.1 - 0.017 15.0 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Secretin_N_2 PF07655.13 CBY11345.1 - 3.7 8.2 13.1 12 6.5 13.1 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain DPBB_1 PF03330.18 CBY11346.1 - 0.02 15.2 0.6 0.21 11.9 0.6 2.6 3 0 0 3 3 3 0 Lytic transglycolase Acetyltransf_1 PF00583.25 CBY11347.1 - 1e-14 54.8 0.0 1.7e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY11347.1 - 4e-11 43.0 0.2 1.1e-10 41.6 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY11347.1 - 4.8e-10 39.7 0.2 1.3e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY11347.1 - 4.3e-09 36.2 0.0 7.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 CBY11347.1 - 0.00041 20.1 0.0 0.00075 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 CBY11347.1 - 0.0038 17.9 0.2 0.01 16.5 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY11347.1 - 0.01 15.9 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cadherin_pro PF08758.11 CBY11347.1 - 0.082 13.1 0.3 0.21 11.8 0.1 1.8 2 1 0 2 2 2 0 Cadherin prodomain like IRK_C PF17655.1 CBY11348.1 - 2.2e-52 177.2 0.0 2.9e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY11348.1 - 3.1e-36 124.3 6.6 6.2e-36 123.3 6.6 1.5 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY11348.1 - 0.042 13.8 10.0 0.08 12.9 9.0 2.0 1 1 1 2 2 2 0 Ion channel Zona_pellucida PF00100.23 CBY11349.1 - 2.6e-17 63.5 4.4 4.8e-17 62.6 4.4 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Laminin_G_3 PF13385.6 CBY11349.1 - 7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CwfJ_C_1 PF04677.15 CBY11350.1 - 6.9e-32 109.9 0.0 1.1e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CBY11350.1 - 4.1e-08 34.0 0.0 9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Striatin PF08232.12 CBY11351.1 - 0.016 15.8 2.8 0.02 15.5 2.8 1.1 1 0 0 1 1 1 0 Striatin family E2F_CC-MB PF16421.5 CBY11351.1 - 0.11 12.9 4.1 0.11 12.9 3.1 1.7 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain APG6_N PF17675.1 CBY11351.1 - 8.3 7.0 13.2 13 6.3 13.1 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region UPF0193 PF05250.11 CBY11352.1 - 9.4e-35 120.4 13.7 1.1e-34 120.2 13.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) VPS28 PF03997.12 CBY11353.1 - 1.9e-50 171.2 2.7 1.9e-50 171.2 2.7 4.7 4 1 0 4 4 4 1 VPS28 protein GRIP PF01465.20 CBY11353.1 - 2.9e-09 36.7 0.0 7.1e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 GRIP domain Sulfotransfer_4 PF17784.1 CBY11353.1 - 0.59 9.9 3.8 31 4.3 1.9 3.4 2 2 1 3 3 3 0 Sulfotransferase domain LRR_6 PF13516.6 CBY11354.1 - 2e-08 33.6 10.1 2 8.7 0.2 6.0 6 0 0 6 6 6 5 Leucine Rich repeat LRR_8 PF13855.6 CBY11354.1 - 0.00031 20.4 6.4 0.064 13.0 0.2 3.8 2 2 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY11354.1 - 0.0071 16.7 12.0 3.4 8.2 0.2 5.0 4 2 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY11354.1 - 0.046 14.3 6.6 1.3 9.8 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich Repeat SNF PF00209.18 CBY11355.1 - 2.6e-162 541.2 34.8 3e-162 541.0 34.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ldl_recept_a PF00057.18 CBY11356.1 - 4.9e-10 39.5 15.9 3.3e-09 36.8 9.2 2.2 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Pyrid_oxidase_2 PF13883.6 CBY11356.1 - 0.063 13.2 0.6 0.13 12.2 0.3 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF3439 PF11921.8 CBY11356.1 - 0.64 10.0 20.9 0.026 14.5 7.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CBY11356.1 - 1.3 7.0 7.3 1.6 6.6 7.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_LBD PF02931.23 CBY11357.1 - 6.8e-34 117.2 0.0 1.4e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY11357.1 - 1.7e-15 57.7 0.1 1.1e-12 48.6 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Alpha-L-AF_C PF06964.12 CBY11358.1 - 0.0077 16.4 1.6 0.012 15.7 1.6 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Decorin_bind PF02352.15 CBY11358.1 - 0.15 12.3 8.7 0.039 14.2 4.4 2.0 1 1 1 2 2 2 0 Decorin binding protein DUF4239 PF14023.6 CBY11358.1 - 1.6 8.4 3.7 12 5.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) EF-hand_4 PF12763.7 CBY11361.1 - 1.8e-12 47.1 0.0 2.2e-11 43.6 0.0 2.6 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CBY11361.1 - 0.0051 16.3 0.0 0.022 14.3 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY11361.1 - 0.0067 16.8 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Cep57_CLD_2 PF14197.6 CBY11361.1 - 0.014 15.5 3.9 0.035 14.2 3.9 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 CBY11361.1 - 0.091 13.2 3.6 0.25 11.8 3.6 1.8 1 0 0 1 1 1 0 Cell division protein ZapB EF-hand_5 PF13202.6 CBY11361.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 EF hand Chromo PF00385.24 CBY11362.1 - 8.8e-15 54.4 2.0 8.8e-15 54.4 2.0 3.0 3 1 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_2 PF18704.1 CBY11362.1 - 0.037 14.3 1.1 0.037 14.3 1.1 4.0 5 1 1 6 6 6 0 Chromatin organization modifier domain 2 EF-hand_4 PF12763.7 CBY11364.1 - 4.6e-12 45.8 0.1 2.2e-11 43.6 0.0 2.2 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CBY11364.1 - 0.0051 16.3 0.0 0.022 14.3 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY11364.1 - 0.0067 16.8 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Cep57_CLD_2 PF14197.6 CBY11364.1 - 0.014 15.5 3.9 0.035 14.2 3.9 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 CBY11364.1 - 0.09 13.2 3.6 0.25 11.8 3.6 1.8 1 0 0 1 1 1 0 Cell division protein ZapB EF-hand_5 PF13202.6 CBY11364.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 EF hand CS PF04969.16 CBY11365.1 - 1.3e-14 54.9 0.8 3.1e-14 53.8 0.8 1.7 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CBY11365.1 - 2.3e-13 49.9 0.7 5.3e-13 48.7 0.7 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. PIH1_CS PF18201.1 CBY11365.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 PIH1 CS-like domain NuDC PF16273.5 CBY11365.1 - 0.019 15.5 13.2 0.019 15.5 13.2 3.4 2 1 1 3 3 3 0 Nuclear distribution C domain IF2_assoc PF08364.11 CBY11365.1 - 0.093 13.0 0.6 0.23 11.7 0.6 1.7 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region Nitro_FeMo-Co PF02579.17 CBY11365.1 - 1 9.8 4.1 3.4 8.0 0.2 2.5 1 1 1 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Enkurin PF13864.6 CBY11367.1 - 7.1e-27 93.7 2.7 1.7e-26 92.5 2.7 1.7 1 0 0 1 1 1 1 Calmodulin-binding SRP54 PF00448.22 CBY11367.1 - 0.089 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TSP_1 PF00090.19 CBY11369.1 - 8.7e-08 32.3 6.2 1.4e-07 31.6 6.2 1.4 1 0 0 1 1 1 1 Thrombospondin type 1 domain Spt4 PF06093.13 CBY11370.1 - 0.071 13.2 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Ras PF00071.22 CBY11372.1 - 1.3e-26 93.1 0.1 1.6e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY11372.1 - 1.3e-09 38.3 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY11372.1 - 1.1e-06 28.3 0.1 1.4e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY11372.1 - 2.6e-06 27.5 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY11372.1 - 0.00019 21.4 0.0 0.082 12.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 CBY11372.1 - 0.0042 17.6 0.0 0.0091 16.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CBY11372.1 - 0.0076 16.7 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF2358 PF10184.9 CBY11372.1 - 0.058 13.7 0.2 0.13 12.6 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) TniB PF05621.11 CBY11372.1 - 0.063 12.7 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 CBY11372.1 - 0.07 13.4 0.0 1.4 9.2 0.0 2.4 2 1 1 3 3 3 0 AAA domain DUF2171 PF09939.9 CBY11372.1 - 0.11 12.8 0.1 0.33 11.3 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) Calx-beta PF03160.14 CBY11373.1 - 0.00019 21.6 0.2 0.038 14.2 0.0 3.9 2 0 0 2 2 2 1 Calx-beta domain ATG16 PF08614.11 CBY11373.1 - 0.00023 21.4 23.7 0.00023 21.4 23.7 28.3 2 2 23 29 29 29 7 Autophagy protein 16 (ATG16) BRE1 PF08647.11 CBY11373.1 - 0.0015 18.6 16.8 0.0015 18.6 16.8 38.2 10 7 22 36 36 36 8 BRE1 E3 ubiquitin ligase GTP_EFTU_D4 PF14578.6 CBY11373.1 - 0.031 14.2 0.1 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 4 TFA2_Winged_2 PF18121.1 CBY11373.1 - 0.42 10.4 9.8 1.9 8.3 0.6 6.3 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 Sulfotransfer_4 PF17784.1 CBY11374.1 - 3.5e-53 180.6 0.1 4.4e-53 180.3 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY11374.1 - 2.3e-05 24.9 0.1 0.00013 22.5 0.0 1.9 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY11374.1 - 0.0014 18.1 0.3 0.014 14.9 0.3 2.3 2 1 0 2 2 2 1 Sulfotransferase domain FGF PF00167.18 CBY11375.1 - 5.3e-13 49.2 0.4 6.7e-13 48.8 0.4 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 CBY11375.1 - 1.8e-09 37.8 0.2 4.3e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Fascin domain FRG1 PF06229.12 CBY11375.1 - 0.028 14.1 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 FRG1-like domain Zona_pellucida PF00100.23 CBY11376.1 - 9.1e-28 97.7 3.2 1.2e-27 97.4 3.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 CBY11377.1 - 2.3e-25 89.9 0.7 2.9e-25 89.6 0.7 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.6 CBY11377.1 - 0.00014 22.1 11.5 0.00054 20.2 10.0 2.8 1 1 1 2 2 2 2 Coagulation Factor Xa inhibitory site Sulfotransfer_2 PF03567.14 CBY11378.1 - 1.1e-22 81.2 0.8 1.4e-22 80.8 0.8 1.2 1 0 0 1 1 1 1 Sulfotransferase family RNaseH_C PF09293.10 CBY11378.1 - 0.15 12.4 1.4 0.68 10.3 0.1 2.3 2 1 1 3 3 3 0 T4 RNase H, C terminal ECH_2 PF16113.5 CBY11379.1 - 1.3e-113 379.9 0.0 1.5e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBY11379.1 - 8.7e-26 90.7 0.0 1.9e-25 89.6 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase HMG-CoA_red PF00368.18 CBY11381.1 - 1.2e-116 389.7 0.1 1.6e-116 389.3 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Holin_BhlA PF10960.8 CBY11381.1 - 0.17 11.8 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 BhlA holin family DUF4729 PF15866.5 CBY11382.1 - 0.14 11.5 0.1 0.14 11.5 0.1 5.1 6 0 0 6 6 6 0 Domain of unknown function (DUF4729) TSP_1 PF00090.19 CBY11383.1 - 4.8e-116 378.9 392.3 4.2e-11 42.9 1.6 31.4 29 3 1 30 30 30 27 Thrombospondin type 1 domain Glycoprotein_G PF00802.19 CBY11384.1 - 0.021 14.2 27.7 0.037 13.4 27.7 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Ndc1_Nup PF09531.10 CBY11384.1 - 1.3 7.6 9.2 1.7 7.2 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mucin PF01456.17 CBY11384.1 - 6.9 6.7 27.7 14 5.7 27.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Mucin PF01456.17 CBY11385.1 - 1.1 9.2 16.7 2.3 8.2 16.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M2 PF01401.18 CBY11386.1 - 7.2e-207 688.5 5.4 8.5e-207 688.3 5.4 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme PKcGMP_CC PF16808.5 CBY11386.1 - 0.0011 18.7 1.1 0.0024 17.7 1.1 1.5 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 CBY11386.1 - 0.019 15.6 0.7 0.049 14.2 0.7 1.6 1 0 0 1 1 1 0 SlyX Fib_alpha PF08702.10 CBY11386.1 - 0.021 15.0 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Kelch_1 PF01344.25 CBY11387.1 - 0.00012 21.6 1.4 0.75 9.4 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY11387.1 - 0.0011 18.9 0.4 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY11387.1 - 0.0032 17.7 0.4 3.6 8.0 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY11387.1 - 0.19 11.8 0.8 7.2 6.8 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Fer4_11 PF13247.6 CBY11388.1 - 0.036 14.2 1.6 0.23 11.6 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Alk_phosphatase PF00245.20 CBY11389.1 - 1.7e-92 310.6 4.4 2.9e-92 309.8 4.4 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 CBY11389.1 - 2.2e-06 27.3 0.0 7.4e-06 25.6 0.0 1.8 1 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 CBY11389.1 - 5.9e-05 22.6 0.6 0.00011 21.6 0.6 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 CBY11389.1 - 0.0044 16.7 0.6 0.0093 15.6 0.6 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase VasI PF11319.8 CBY11389.1 - 0.03 14.0 0.2 0.064 12.9 0.2 1.5 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 NYN_YacP PF05991.11 CBY11389.1 - 0.34 10.9 2.4 1.5 8.7 0.1 2.8 3 0 0 3 3 3 0 YacP-like NYN domain Phospholip_A2_1 PF00068.19 CBY11390.1 - 1.3e-15 57.8 6.1 1.3e-15 57.8 6.1 1.6 2 0 0 2 2 2 1 Phospholipase A2 Glyco_hydro_16 PF00722.21 CBY11391.1 - 7.8e-26 90.6 0.5 1.1e-25 90.1 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 CBY11391.1 - 0.016 15.3 0.5 0.03 14.4 0.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) X8 PF07983.13 CBY11391.1 - 2.1 9.1 12.5 7.1 7.4 12.5 2.0 1 1 0 1 1 1 0 X8 domain Cadherin_C_2 PF16492.5 CBY11392.1 - 0.089 13.6 0.0 0.092 13.5 0.0 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Cwf_Cwc_15 PF04889.12 CBY11392.1 - 2.5 7.8 8.0 2.8 7.6 8.0 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein KxDL PF10241.9 CBY11394.1 - 0.099 12.9 2.4 4.5 7.6 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein MRG PF05712.13 CBY11394.1 - 0.24 10.7 1.5 6.2 6.1 0.1 3.2 3 1 1 4 4 4 0 MRG Type2_restr_D3 PF16902.5 CBY11394.1 - 0.94 9.4 4.3 1.5 8.7 0.2 2.8 3 0 0 3 3 3 0 Type-2 restriction enzyme D3 domain YmgB PF10798.8 CBY11394.1 - 7.8 6.4 7.5 0.59 10.0 0.2 3.0 5 0 0 5 5 5 0 Biofilm development protein YmgB/AriR DUF536 PF04394.14 CBY11395.1 - 0.03 14.2 3.2 5.6 6.9 1.0 3.5 2 0 0 2 2 2 0 Protein of unknown function, DUF536 LMSTEN PF07988.12 CBY11395.1 - 0.33 10.5 4.1 0.29 10.6 2.0 2.0 2 0 0 2 2 2 0 LMSTEN motif AKAP7_NLS PF10469.9 CBY11395.1 - 0.37 10.6 6.9 0.28 11.1 3.7 2.2 1 1 1 2 2 2 0 AKAP7 2'5' RNA ligase-like domain Phlebovirus_NSM PF07246.11 CBY11395.1 - 0.48 9.7 15.5 0.34 10.2 5.3 2.5 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M CarbpepA_inh PF02977.15 CBY11396.1 - 0.19 11.5 3.9 3.6 7.5 0.0 2.3 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Carn_acyltransf PF00755.20 CBY11397.1 - 9.3e-103 344.9 0.0 1.1e-102 344.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 CBY11398.1 - 4.5e-24 85.0 17.1 4.5e-24 85.0 17.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Clat_adaptor_s PF01217.20 CBY11399.1 - 1.3e-46 158.1 1.1 1.5e-46 157.9 1.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HOCHOB PF17943.1 CBY11399.1 - 0.017 15.9 0.5 0.11 13.2 0.5 2.1 1 1 0 1 1 1 0 Homeobox-cysteine loop-homeobox MRG PF05712.13 CBY11399.1 - 0.077 12.3 0.1 0.099 11.9 0.1 1.3 1 0 0 1 1 1 0 MRG Seryl_tRNA_N PF02403.22 CBY11401.1 - 0.0019 18.4 2.9 0.0035 17.5 2.9 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.14 CBY11401.1 - 0.016 15.0 1.0 0.026 14.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF643 PF04867.12 CBY11401.1 - 0.021 15.4 0.1 0.031 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF643) SIKE PF05769.11 CBY11401.1 - 0.024 14.6 0.2 0.032 14.2 0.2 1.2 1 0 0 1 1 1 0 SIKE family Cauli_AT PF03233.13 CBY11401.1 - 0.025 14.5 0.2 0.028 14.4 0.2 1.2 1 0 0 1 1 1 0 Aphid transmission protein Tho2 PF11262.8 CBY11401.1 - 0.051 12.8 0.4 0.083 12.1 0.4 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.9 CBY11401.1 - 0.072 12.2 2.1 0.11 11.6 2.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 CBY11401.1 - 0.074 13.5 0.7 0.12 12.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DASH_Spc19 PF08287.11 CBY11401.1 - 0.099 12.5 3.7 0.068 13.1 1.7 1.7 1 1 1 2 2 2 0 Spc19 Fzo_mitofusin PF04799.13 CBY11401.1 - 0.15 11.6 0.7 0.21 11.1 0.7 1.2 1 0 0 1 1 1 0 fzo-like conserved region TMPIT PF07851.13 CBY11401.1 - 0.16 11.2 0.3 0.23 10.7 0.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spectrin PF00435.21 CBY11403.1 - 0.0019 18.6 3.4 0.0019 18.6 3.4 19.7 18 5 5 24 24 24 4 Spectrin repeat Tir_receptor_N PF07490.11 CBY11403.1 - 0.0023 17.8 2.2 1.4 8.7 0.1 4.5 5 0 0 5 5 5 1 Translocated intimin receptor (Tir) N-terminus Nbl1_Borealin_N PF10444.9 CBY11403.1 - 4.9 6.9 7.5 4.3 7.1 0.1 5.0 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal GAPES1 PF17155.4 CBY11404.1 - 0.0025 17.2 0.3 0.0053 16.1 0.3 1.5 1 0 0 1 1 1 1 Gammaproteobacterial periplasmic sensor domain DUF2937 PF11157.8 CBY11404.1 - 1.5 8.5 4.0 6.5 6.4 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2937) DUF1153 PF06627.11 CBY11404.1 - 1.6 8.9 3.7 3.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) T7SS_ESX_EspC PF10824.8 CBY11404.1 - 2.8 8.5 12.6 0.62 10.6 0.4 5.4 5 0 0 5 5 5 0 Excreted virulence factor EspC, type VII ESX diderm CH PF00307.31 CBY11405.1 - 1.1e-09 38.5 0.0 1.3e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Pkinase PF00069.25 CBY11406.1 - 1.3e-18 67.4 0.5 2.8e-17 63.0 0.0 2.6 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11406.1 - 1.1e-10 41.3 0.8 9.9e-10 38.1 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase DUF724 PF05266.14 CBY11406.1 - 0.013 15.4 6.0 0.013 15.4 6.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Amidoligase_2 PF12224.8 CBY11406.1 - 0.014 15.1 0.6 0.05 13.3 0.2 1.9 1 1 1 2 2 2 0 Putative amidoligase enzyme Elf4 PF07011.11 CBY11406.1 - 0.014 15.3 0.8 0.031 14.2 0.2 1.9 1 1 1 2 2 2 0 Early Flowering 4 domain Fib_alpha PF08702.10 CBY11406.1 - 0.043 14.0 5.6 0.5 10.5 1.6 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Phlebovirus_NSM PF07246.11 CBY11406.1 - 0.064 12.6 5.4 0.13 11.6 5.4 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FapA PF03961.13 CBY11406.1 - 1.1 7.7 9.6 1.7 7.2 9.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-F_leu_zip PF10473.9 CBY11406.1 - 1.3 9.1 18.6 3.5 7.6 18.6 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 CBY11406.1 - 7.1 5.9 8.9 10 5.4 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CBY11406.1 - 8.6 6.9 17.3 31 5.1 17.3 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4337 PF14235.6 CBY11406.1 - 9.4 6.3 7.3 17 5.5 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF755 PF05501.11 CBY11408.1 - 0.067 13.5 8.0 0.075 13.3 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4692 PF15763.5 CBY11408.1 - 0.44 11.0 3.3 0.52 10.8 3.3 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Ldl_recept_b PF00058.17 CBY11409.1 - 1.1e-20 73.8 14.5 0.00015 22.1 0.0 10.0 11 0 0 11 11 11 4 Low-density lipoprotein receptor repeat class B HYR PF02494.16 CBY11409.1 - 5.9e-14 52.2 4.6 6.5e-11 42.4 0.0 4.3 4 1 0 4 4 4 2 HYR domain FXa_inhibition PF14670.6 CBY11409.1 - 6.3e-08 32.8 55.5 3.8e-05 23.9 8.7 5.7 6 0 0 6 6 6 3 Coagulation Factor Xa inhibitory site Ephrin_rec_like PF07699.13 CBY11409.1 - 9.7e-08 31.7 2.5 9.7e-08 31.7 2.5 2.7 1 1 1 2 2 2 1 Putative ephrin-receptor like SGL PF08450.12 CBY11409.1 - 4.8e-05 23.1 2.9 0.72 9.4 0.2 5.5 4 2 1 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CBY11409.1 - 0.00014 21.9 0.0 8.1 6.7 0.0 6.3 7 1 0 7 7 7 1 Arylesterase fn1 PF00039.18 CBY11409.1 - 0.00014 21.9 5.8 0.00035 20.7 5.8 1.7 1 0 0 1 1 1 1 Fibronectin type I domain FAM176 PF14851.6 CBY11409.1 - 0.00036 20.2 1.6 0.00036 20.2 1.6 2.3 1 1 1 2 2 1 1 FAM176 family EphA2_TM PF14575.6 CBY11409.1 - 0.0014 19.5 0.1 0.004 18.0 0.1 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 CBY11409.1 - 0.11 12.8 0.4 0.27 11.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FimA PF16970.5 CBY11409.1 - 0.21 11.8 1.0 0.64 10.2 0.5 2.0 2 0 0 2 2 2 0 Type-1 fimbrial protein, A Neur_chan_memb PF02932.16 CBY11409.1 - 0.37 10.8 2.6 0.79 9.7 2.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.6 CBY11409.1 - 1.3 8.9 8.9 0.13 12.1 1.4 2.3 1 1 0 2 2 2 0 Transmembrane protein 51 EGF PF00008.27 CBY11409.1 - 3.4 8.1 38.0 1.5 9.2 8.9 4.8 4 0 0 4 4 4 0 EGF-like domain Nop25 PF09805.9 CBY11409.1 - 8.4 6.9 23.1 17 5.9 23.1 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) LRR_8 PF13855.6 CBY11410.1 - 1.7e-23 82.2 10.0 3.3e-14 52.4 4.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY11410.1 - 2.2e-09 37.4 10.2 1.5e-06 28.4 3.2 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY11410.1 - 1.6e-07 31.3 0.0 3.9e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBY11410.1 - 1.1e-06 28.4 5.4 0.15 12.7 0.1 4.1 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_9 PF14580.6 CBY11410.1 - 0.0079 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 CBY11410.1 - 0.19 11.9 5.6 2.1 8.6 0.2 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 CBY11411.1 - 2.9e-14 52.5 2.2 4.9e-11 42.2 0.4 2.9 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY11411.1 - 3.6e-10 39.9 8.0 7.6e-05 23.0 0.1 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY11411.1 - 6.3e-06 25.8 0.2 0.00096 18.7 0.0 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CBY11411.1 - 0.072 13.7 4.9 16 6.5 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat Trypsin PF00089.26 CBY11412.1 - 6.8e-17 62.0 0.0 1.4e-16 61.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY11412.1 - 0.0082 17.1 0.0 0.016 16.1 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Cyclin_N PF00134.23 CBY11413.1 - 5.4e-22 77.9 0.1 1.1e-21 77.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY11413.1 - 5.2e-13 49.1 0.4 5.2e-13 49.1 0.4 2.8 3 0 0 3 3 3 1 Cyclin, C-terminal domain Trypsin PF00089.26 CBY11415.1 - 8.2e-07 29.1 0.0 8.7e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Trypsin Striatin PF08232.12 CBY11416.1 - 0.0079 16.8 18.5 0.44 11.1 8.1 2.6 1 1 1 2 2 2 2 Striatin family FapA PF03961.13 CBY11416.1 - 0.086 11.4 10.5 0.11 11.0 10.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mu-like_Pro PF10123.9 CBY11416.1 - 0.096 12.2 6.5 0.14 11.7 6.5 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein V_ATPase_I PF01496.19 CBY11416.1 - 0.11 10.5 7.2 0.12 10.3 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SHE3 PF17078.5 CBY11416.1 - 0.12 12.1 14.8 0.21 11.3 14.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 FAM76 PF16046.5 CBY11416.1 - 0.18 11.2 11.8 0.23 10.8 11.8 1.1 1 0 0 1 1 1 0 FAM76 protein MRPL52 PF18699.1 CBY11416.1 - 0.18 12.0 10.7 0.5 10.6 10.7 1.8 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Macoilin PF09726.9 CBY11416.1 - 3.9 5.9 12.9 5.3 5.5 12.9 1.2 1 0 0 1 1 1 0 Macoilin family DUF3450 PF11932.8 CBY11416.1 - 4.3 6.6 21.7 0.7 9.2 8.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADK PF00406.22 CBY11417.1 - 1.3e-16 61.1 0.7 3.8e-10 40.1 0.0 3.6 3 1 1 4 4 3 2 Adenylate kinase AAA_17 PF13207.6 CBY11417.1 - 1.6e-07 31.9 0.3 0.041 14.3 0.0 3.7 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.6 CBY11417.1 - 4e-07 30.3 1.9 0.17 12.1 0.5 4.6 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.6 CBY11417.1 - 4.5e-06 27.2 0.4 0.14 12.7 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CBY11417.1 - 6.1e-06 26.3 0.1 0.028 14.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY11417.1 - 4.6e-05 23.9 0.3 0.087 13.2 0.0 3.2 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 CBY11417.1 - 7.6e-05 22.5 0.0 0.06 13.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.29 CBY11417.1 - 0.0002 21.8 0.0 0.0036 17.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CBY11417.1 - 0.00023 20.6 0.1 0.22 10.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 CBY11417.1 - 0.0012 18.9 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 CBY11417.1 - 0.0024 18.2 0.0 0.079 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBY11417.1 - 0.012 15.9 0.0 0.66 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF5582 PF17819.1 CBY11417.1 - 0.013 16.0 0.1 0.031 14.7 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5582) NACHT PF05729.12 CBY11417.1 - 0.013 15.4 0.7 0.64 9.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 CBY11417.1 - 0.026 14.3 0.2 0.34 10.6 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein NB-ARC PF00931.22 CBY11417.1 - 0.027 13.7 0.0 0.098 11.8 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.17 CBY11417.1 - 0.034 13.2 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SKI PF01202.22 CBY11417.1 - 0.034 14.3 0.6 17 5.5 0.0 3.6 4 0 0 4 4 4 0 Shikimate kinase G-alpha PF00503.20 CBY11417.1 - 0.037 13.2 0.1 6.5 5.8 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit AAA_25 PF13481.6 CBY11417.1 - 0.044 13.4 0.4 0.19 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CBY11417.1 - 0.057 13.9 0.7 1.5 9.4 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_2 PF07724.14 CBY11417.1 - 0.063 13.4 0.0 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IPT PF01745.16 CBY11417.1 - 0.069 12.5 0.2 0.83 9.0 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase TsaE PF02367.17 CBY11417.1 - 0.075 13.0 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBY11417.1 - 0.13 11.8 0.0 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Glyco_hydro_28 PF00295.17 CBY11419.1 - 2e-29 102.7 0.1 2.5e-29 102.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CBY11419.1 - 0.0059 16.5 0.7 0.011 15.6 0.7 1.4 1 1 0 1 1 1 1 Right handed beta helix region SRCR PF00530.18 CBY11420.1 - 4.4e-05 23.9 2.2 7.5e-05 23.2 0.1 2.2 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain TSP_1 PF00090.19 CBY11420.1 - 5.5 7.3 12.6 0.58 10.4 7.6 2.0 2 0 0 2 2 2 0 Thrombospondin type 1 domain Chibby PF14645.6 CBY11421.1 - 5.4e-23 81.6 2.0 6.6e-23 81.3 2.0 1.1 1 0 0 1 1 1 1 Chibby family ApoB100_C PF12491.8 CBY11422.1 - 0.061 13.3 0.5 2.2 8.3 0.1 3.4 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal FhuF PF06276.12 CBY11422.1 - 0.065 13.7 0.0 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Ferric iron reductase FhuF-like transporter FAD-oxidase_C PF02913.19 CBY11424.1 - 7.9e-59 199.3 0.0 1e-58 198.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBY11424.1 - 1e-37 128.9 0.3 1.7e-37 128.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain zf-RING_5 PF14634.6 CBY11425.1 - 4.8e-07 29.6 7.2 1.1e-06 28.5 7.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY11425.1 - 2.2e-05 24.7 7.2 4.5e-05 23.7 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY11425.1 - 0.00017 21.4 5.9 0.00026 20.8 3.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY11425.1 - 0.00023 21.1 1.7 0.00023 21.1 1.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY11425.1 - 0.00032 20.5 8.3 0.00064 19.5 8.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HIGH_NTase1 PF05636.11 CBY11425.1 - 0.00081 18.7 0.2 0.00084 18.7 0.2 1.1 1 0 0 1 1 1 1 HIGH Nucleotidyl Transferase zf-C3HC4_2 PF13923.6 CBY11425.1 - 0.0071 16.2 7.4 0.0071 16.2 7.4 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY11425.1 - 0.015 15.1 8.0 0.027 14.3 8.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mvb12 PF09452.10 CBY11425.1 - 0.035 14.5 0.2 0.058 13.8 0.2 1.3 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 She9_MDM33 PF05546.11 CBY11425.1 - 0.045 13.5 1.4 0.061 13.1 1.4 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family FYVE PF01363.21 CBY11425.1 - 0.062 13.4 2.2 0.062 13.4 2.2 2.4 2 1 1 3 3 3 0 FYVE zinc finger Barstar PF01337.18 CBY11425.1 - 0.08 13.0 0.1 0.16 12.1 0.1 1.5 1 1 0 1 1 1 0 Barstar (barnase inhibitor) Rtf2 PF04641.12 CBY11425.1 - 1.5 8.1 11.1 1.6 8.0 8.4 1.9 1 1 1 2 2 2 0 Rtf2 RING-finger Phospholip_A2_1 PF00068.19 CBY11427.1 - 3e-11 43.8 10.1 3e-11 43.8 10.1 2.1 2 0 0 2 2 2 1 Phospholipase A2 FixO PF02433.15 CBY11427.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Phage_H_T_join PF05521.11 CBY11428.1 - 0.037 14.5 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 Phage head-tail joining protein DUF5137 PF17220.3 CBY11428.1 - 0.1 13.5 0.1 0.21 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF5137) TSP_1 PF00090.19 CBY11429.1 - 7.4e-10 38.9 27.4 3.4e-08 33.6 7.2 7.8 7 1 0 7 7 7 4 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 CBY11429.1 - 2.5e-05 24.3 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 CBY11429.1 - 0.00073 20.0 1.4 0.00073 20.0 1.4 7.0 5 2 1 7 7 7 2 ADAM cysteine-rich domain DUF5114 PF17141.4 CBY11429.1 - 0.072 13.6 0.0 0.29 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5114) Ig_3 PF13927.6 CBY11430.1 - 1e-15 58.1 0.0 5.2e-11 43.0 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY11430.1 - 8.3e-10 38.6 0.0 5.5e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain ZU5 PF00791.20 CBY11430.1 - 7.2e-09 35.9 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain Ig_2 PF13895.6 CBY11430.1 - 2.2e-08 34.3 0.0 4.5e-07 30.1 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 CBY11430.1 - 3.9e-07 30.2 0.0 9.7e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.19 CBY11430.1 - 0.00024 21.2 7.3 0.00024 21.2 7.3 3.1 3 0 0 3 3 3 2 Thrombospondin type 1 domain C2-set_2 PF08205.12 CBY11430.1 - 0.0067 16.5 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CBY11430.1 - 0.018 14.6 0.1 0.088 12.4 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain UPA PF17217.3 CBY11430.1 - 0.023 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 UPA domain DnaJ PF00226.31 CBY11431.1 - 1.2e-07 31.7 0.0 0.0043 17.2 0.0 3.2 1 1 1 2 2 2 2 DnaJ domain RPT PF13446.6 CBY11431.1 - 0.04 13.8 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein HAUS6_N PF14661.6 CBY11431.1 - 0.27 10.8 7.7 0.096 12.2 4.2 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FlxA PF14282.6 CBY11431.1 - 3.7 7.6 11.9 0.15 12.1 5.6 1.8 2 0 0 2 2 2 0 FlxA-like protein DUF724 PF05266.14 CBY11431.1 - 4 7.2 14.1 0.7 9.7 8.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Mg296 PF09644.10 CBY11433.1 - 0.052 13.7 0.7 0.11 12.7 0.3 1.6 2 0 0 2 2 2 0 Mg296 protein Myosin_head PF00063.21 CBY11434.1 - 8.2e-87 292.0 0.0 8.2e-87 292.0 0.0 2.3 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY11434.1 - 1e-19 70.0 128.3 9.4e-17 60.2 113.9 3.2 1 1 1 2 2 2 2 Myosin tail PDZ PF00595.24 CBY11434.1 - 7.2e-09 35.9 0.0 2.1e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY11434.1 - 1.4e-08 34.5 0.0 3.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain IQ PF00612.27 CBY11434.1 - 0.0038 16.9 5.9 0.53 10.2 0.4 3.5 3 0 0 3 3 3 2 IQ calmodulin-binding motif PDZ_2 PF13180.6 CBY11434.1 - 0.016 15.5 0.1 0.076 13.3 0.0 2.2 2 0 0 2 2 2 0 PDZ domain Tricorn_PDZ PF14685.6 CBY11434.1 - 0.12 12.3 0.0 4 7.5 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain Ribonuc_red_2_N PF08471.10 CBY11435.1 - 0.034 14.3 0.2 0.043 14.0 0.2 1.2 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase Macoilin PF09726.9 CBY11436.1 - 0.0014 17.3 12.7 0.0019 16.9 12.7 1.1 1 0 0 1 1 1 1 Macoilin family GAS PF13851.6 CBY11436.1 - 0.002 17.5 13.2 0.002 17.5 13.2 2.7 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding JAKMIP_CC3 PF16034.5 CBY11436.1 - 0.0031 17.5 4.6 0.0031 17.5 4.6 2.6 2 1 1 3 3 2 1 JAKMIP CC3 domain Leu_zip PF15294.6 CBY11436.1 - 0.0043 16.6 9.1 0.007 15.9 9.1 1.5 1 0 0 1 1 1 1 Leucine zipper JIP_LZII PF16471.5 CBY11436.1 - 0.0095 16.1 1.3 0.0095 16.1 1.3 3.0 1 1 0 2 2 2 1 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 CBY11436.1 - 0.029 13.7 9.4 0.061 12.6 9.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 CBY11436.1 - 0.044 14.2 2.7 0.044 14.2 2.7 2.8 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) HSBP1 PF06825.12 CBY11436.1 - 0.052 13.4 0.0 0.64 9.9 0.2 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF2205 PF10224.9 CBY11436.1 - 0.058 13.4 10.5 0.063 13.3 3.6 2.8 1 1 1 2 2 2 0 Short coiled-coil protein MCC-bdg_PDZ PF10506.9 CBY11436.1 - 0.083 12.9 4.5 0.1 12.7 0.5 2.5 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome APC_N_CC PF16689.5 CBY11436.1 - 0.095 12.8 4.8 0.31 11.1 0.6 3.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1664 PF07889.12 CBY11436.1 - 0.15 12.1 4.2 0.4 10.7 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 CBY11436.1 - 0.15 9.9 7.6 0.21 9.5 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NYD-SP28_assoc PF14775.6 CBY11436.1 - 0.18 12.0 13.9 1.1 9.4 0.9 3.9 2 1 1 3 3 3 0 Sperm tail C-terminal domain TolA_bind_tri PF16331.5 CBY11436.1 - 0.39 10.8 5.8 0.7 10.0 4.9 1.9 1 1 0 1 1 1 0 TolA binding protein trimerisation Fez1 PF06818.15 CBY11436.1 - 0.52 10.7 13.7 0.049 14.1 9.2 1.6 2 0 0 2 2 1 0 Fez1 HAUS-augmin3 PF14932.6 CBY11436.1 - 0.69 9.4 10.5 1.1 8.7 10.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fmp27_WPPW PF10359.9 CBY11436.1 - 0.75 8.6 9.0 1.2 7.9 9.0 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Syntaxin-6_N PF09177.11 CBY11436.1 - 0.79 10.3 9.7 0.35 11.4 6.1 2.3 2 1 1 3 3 2 0 Syntaxin 6, N-terminal DivIC PF04977.15 CBY11436.1 - 1 9.2 13.1 1.4 8.7 3.5 3.3 2 1 1 3 3 3 0 Septum formation initiator dCache_2 PF08269.11 CBY11436.1 - 1.1 8.3 10.2 0.6 9.2 7.8 1.7 2 0 0 2 2 2 0 Cache domain Nnf1 PF03980.14 CBY11436.1 - 1.4 9.3 14.9 2.5 8.5 5.8 3.1 2 1 0 2 2 2 0 Nnf1 LCD1 PF09798.9 CBY11436.1 - 1.6 7.2 12.3 7.7 4.9 0.6 1.7 1 1 1 2 2 2 0 DNA damage checkpoint protein bZIP_1 PF00170.21 CBY11436.1 - 1.7 8.8 18.6 0.08 13.0 3.2 3.6 1 1 3 4 4 4 0 bZIP transcription factor SHE3 PF17078.5 CBY11436.1 - 2.1 8.0 19.2 0.1 12.3 13.0 1.9 3 0 0 3 3 2 0 SWI5-dependent HO expression protein 3 YabA PF06156.13 CBY11436.1 - 3.4 8.3 17.8 0.43 11.2 7.8 2.8 2 1 1 3 3 2 0 Initiation control protein YabA Spc29 PF17082.5 CBY11436.1 - 3.6 7.4 11.9 0.24 11.2 3.2 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 SlyX PF04102.12 CBY11436.1 - 5.4 7.7 6.2 16 6.2 2.8 3.1 2 1 1 3 3 2 0 SlyX TSC22 PF01166.18 CBY11436.1 - 5.5 7.4 13.6 12 6.3 0.6 4.2 2 1 1 3 3 3 0 TSC-22/dip/bun family Atg14 PF10186.9 CBY11436.1 - 6.6 5.7 9.8 10 5.1 9.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 CBY11436.1 - 8.3 5.2 16.8 31 3.3 16.8 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Ax_dynein_light PF10211.9 CBY11436.1 - 9.3 6.1 23.2 0.053 13.5 11.1 2.5 2 1 1 3 3 2 0 Axonemal dynein light chain Utp11 PF03998.13 CBY11437.1 - 5.9e-45 154.1 7.6 7e-45 153.9 7.6 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 CBY11437.1 - 0.07 12.5 0.3 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 PAT1 PF09770.9 CBY11438.1 - 6.6e-05 21.4 1.2 0.01 14.1 0.1 2.9 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 DUF900 PF05990.12 CBY11438.1 - 0.039 13.5 0.3 6.2 6.2 0.0 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) Ribosomal_L18A PF01775.17 CBY11440.1 - 3.1e-49 166.1 0.0 5.8e-49 165.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Rrp15p PF07890.12 CBY11440.1 - 1.2 9.5 10.1 0.28 11.5 4.1 2.1 2 0 0 2 2 2 0 Rrp15p Pap_E4 PF02711.14 CBY11440.1 - 2.6 9.1 9.3 3.3 8.7 1.6 2.3 2 0 0 2 2 2 0 E4 protein DUF4200 PF13863.6 CBY11442.1 - 6.6e-28 97.5 16.4 6.6e-28 97.5 16.4 5.1 4 1 1 5 5 5 1 Domain of unknown function (DUF4200) SRP_SPB PF02978.19 CBY11442.1 - 0.0002 21.9 1.3 0.0015 19.1 0.8 2.8 1 1 0 1 1 1 1 Signal peptide binding domain Baculo_PEP_C PF04513.12 CBY11442.1 - 0.0051 16.9 2.1 0.054 13.5 0.5 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1251 PF06856.11 CBY11442.1 - 0.12 12.1 2.1 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1251) LdpA_C PF12617.8 CBY11443.1 - 0.17 11.4 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal ENTH PF01417.20 CBY11444.1 - 1.4e-38 131.8 0.1 1.7e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 CBY11444.1 - 0.00039 20.3 0.0 0.00048 20.0 0.0 1.1 1 0 0 1 1 1 1 VHS domain ANTH PF07651.16 CBY11444.1 - 0.00082 18.4 0.0 0.00094 18.3 0.0 1.0 1 0 0 1 1 1 1 ANTH domain Ribonuc_2-5A PF06479.12 CBY11444.1 - 0.0019 18.4 0.0 0.0037 17.4 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease 2-5A ENTH PF01417.20 CBY11445.1 - 3.2e-47 159.7 0.2 5.1e-47 159.0 0.2 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 CBY11445.1 - 0.00051 19.9 0.1 0.00087 19.1 0.1 1.3 1 0 0 1 1 1 1 VHS domain ANTH PF07651.16 CBY11445.1 - 0.00061 18.9 0.1 0.0011 18.1 0.1 1.4 1 0 0 1 1 1 1 ANTH domain RAP80_UIM PF18282.1 CBY11445.1 - 0.025 14.3 9.7 0.092 12.5 9.7 1.9 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Ribonuc_2-5A PF06479.12 CBY11445.1 - 0.033 14.4 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease 2-5A UIM PF02809.20 CBY11445.1 - 0.3 11.1 10.8 0.069 13.1 6.5 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif Trypsin PF00089.26 CBY11446.1 - 8.9e-44 149.9 0.3 1.4e-43 149.3 0.3 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY11446.1 - 0.0011 19.4 0.0 0.0025 18.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY11446.1 - 0.011 16.6 0.0 0.035 15.0 0.0 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain DUF547 PF04784.14 CBY11448.1 - 1.3e-33 115.7 0.0 2.5e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Glutaredoxin PF00462.24 CBY11448.1 - 3.3e-14 52.9 0.0 1e-13 51.3 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin DEP PF00610.21 CBY11448.1 - 0.0048 16.9 0.0 0.013 15.5 0.0 1.8 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GST_N_3 PF13417.6 CBY11448.1 - 0.018 15.4 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF4520 PF15016.6 CBY11448.1 - 0.027 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DUF5032 PF16435.5 CBY11448.1 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) DUF836 PF05768.14 CBY11448.1 - 0.095 13.1 0.3 0.59 10.6 0.1 2.6 2 1 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Trypsin PF00089.26 CBY11450.1 - 2e-24 86.6 0.1 2.4e-24 86.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin SRP72 PF08492.12 CBY11452.1 - 0.13 12.7 0.5 0.13 12.7 0.5 2.9 4 0 0 4 4 4 0 SRP72 RNA-binding domain NUDE_C PF04880.13 CBY11453.1 - 6.5e-17 62.6 9.2 6.5e-17 62.6 9.2 2.2 2 0 0 2 2 1 1 NUDE protein, C-terminal conserved region HJURP_C PF12347.8 CBY11453.1 - 0.0014 18.6 2.4 0.14 12.2 0.5 2.7 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat Dynein_attach_N PF15867.5 CBY11453.1 - 0.024 14.6 0.6 0.024 14.6 0.6 2.8 2 1 2 4 4 4 0 Dynein attachment factor N-terminus TPR_MLP1_2 PF07926.12 CBY11453.1 - 0.22 11.6 27.6 1.9 8.6 8.4 2.7 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2433 PF10360.9 CBY11453.1 - 0.47 10.6 13.6 1.9 8.6 3.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2433) YabA PF06156.13 CBY11453.1 - 0.55 10.9 23.8 3 8.5 4.4 3.1 2 1 1 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 CBY11453.1 - 0.94 9.5 10.3 1.3 9.0 3.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CBY11453.1 - 1.1 8.6 12.2 3 7.1 11.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CBY11453.1 - 3 7.9 26.9 0.18 11.9 11.7 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding MbeD_MobD PF04899.12 CBY11453.1 - 3.2 7.9 10.2 2.1 8.5 0.7 3.0 1 1 2 3 3 3 0 MbeD/MobD like DUF1635 PF07795.11 CBY11453.1 - 3.5 7.4 22.4 2.3 8.0 15.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) Spc7 PF08317.11 CBY11453.1 - 6.9 5.4 25.7 16 4.3 25.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Ras PF00071.22 CBY11455.1 - 4.3e-47 159.7 3.1 5.9e-43 146.3 0.4 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 CBY11455.1 - 7.3e-26 90.7 4.3 1.6e-21 76.7 0.1 2.7 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY11455.1 - 2.7e-13 49.8 0.6 9.7e-12 44.7 0.1 2.1 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY11455.1 - 1.2e-07 31.4 0.3 2.9e-07 30.2 0.3 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CBY11455.1 - 0.00021 21.1 1.2 0.0031 17.3 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CBY11455.1 - 0.00025 21.0 0.8 0.24 11.3 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBY11455.1 - 0.0032 17.5 0.9 1.7 8.8 0.0 2.4 1 1 1 2 2 2 2 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CBY11455.1 - 0.0072 16.3 0.1 0.01 15.8 0.1 1.2 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 CBY11455.1 - 0.032 14.6 0.0 0.043 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 CBY11455.1 - 0.032 13.6 1.6 0.57 9.5 0.1 2.2 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CBY11455.1 - 0.048 13.9 0.1 0.11 12.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY11455.1 - 0.071 13.5 0.2 0.45 10.9 0.0 2.1 1 1 1 2 2 2 0 RNA helicase AAA_29 PF13555.6 CBY11455.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CBY11455.1 - 0.081 12.5 0.5 5.4 6.5 0.1 2.2 1 1 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 CBY11455.1 - 0.082 12.3 0.1 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Prp19 PF08606.11 CBY11456.1 - 2.2e-28 98.0 2.5 4.7e-28 97.0 2.5 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CBY11456.1 - 2.2e-23 82.1 9.2 0.00012 22.8 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY11456.1 - 2.9e-12 46.7 0.7 0.098 13.0 0.0 5.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 CBY11456.1 - 1.4e-06 28.4 0.0 3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain Nup160 PF11715.8 CBY11456.1 - 0.0042 15.8 0.0 0.17 10.5 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ten1_2 PF15490.6 CBY11456.1 - 0.083 12.6 0.7 0.19 11.5 0.7 1.5 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit DUF5129 PF17173.4 CBY11456.1 - 0.23 10.5 3.1 0.14 11.2 1.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5129) TPR_MLP1_2 PF07926.12 CBY11456.1 - 0.85 9.7 7.6 2 8.5 7.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 CBY11456.1 - 2 8.9 6.1 1.2 9.5 3.4 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) RNA_pol_A_bac PF01000.26 CBY11457.1 - 7.6e-20 71.4 1.6 9.4e-19 67.8 0.2 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBY11457.1 - 6.2e-19 67.2 0.0 1.3e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Epimerase PF01370.21 CBY11458.1 - 9.8e-06 25.2 0.0 1.5e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBY11458.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CBY11458.1 - 0.015 14.8 0.2 0.04 13.3 0.1 1.7 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 CBY11458.1 - 0.022 14.4 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 CBY11458.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family DUF1731 PF08338.11 CBY11460.1 - 3.4e-08 33.2 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Fumble PF03630.14 CBY11461.1 - 6.8e-111 370.6 0.0 9.7e-111 370.1 0.0 1.2 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 CBY11461.1 - 2.2e-42 145.3 0.4 3.5e-42 144.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF3297 PF11730.8 CBY11462.1 - 0.05 13.5 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Caskin-Pro-rich PF16907.5 CBY11462.1 - 0.066 13.7 0.1 0.073 13.6 0.1 1.0 1 0 0 1 1 1 0 Proline rich region of Caskin proteins DUF573 PF04504.14 CBY11462.1 - 0.078 13.6 0.9 0.079 13.6 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF573 MAM PF00629.23 CBY11464.1 - 1.3e-05 25.2 0.9 0.054 13.4 0.0 2.6 3 0 0 3 3 3 2 MAM domain, meprin/A5/mu Trypsin PF00089.26 CBY11465.1 - 3.7e-27 95.6 2.2 3.7e-27 95.6 2.2 1.7 2 0 0 2 2 2 1 Trypsin LRR_4 PF12799.7 CBY11465.1 - 2.7e-12 46.7 25.3 0.00021 21.6 2.2 4.7 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY11465.1 - 8.3e-09 35.1 27.9 0.00049 19.8 9.0 4.8 3 1 1 4 4 4 4 Leucine rich repeat DUF316 PF03761.15 CBY11465.1 - 0.00078 19.1 0.2 0.34 10.4 0.1 2.2 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 LRR_1 PF00560.33 CBY11465.1 - 0.0043 17.4 18.9 7.4 7.5 1.1 7.7 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 CBY11465.1 - 0.0057 16.6 11.6 3.4 8.0 0.1 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 CBY11465.1 - 0.27 10.7 12.8 0.21 11.1 4.3 3.0 2 1 3 5 5 5 0 Leucine-rich repeat TMF_TATA_bd PF12325.8 CBY11465.1 - 0.29 11.4 6.9 2.1 8.6 3.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BRX_N PF13713.6 CBY11467.1 - 0.15 11.9 0.8 0.34 10.7 0.8 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Integrase_H2C2 PF17921.1 CBY11468.1 - 6.3e-05 23.0 0.1 0.00018 21.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain PT-TG PF14449.6 CBY11468.1 - 0.035 14.0 0.0 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 Pre-toxin TG Sushi PF00084.20 CBY11469.1 - 0.0014 19.2 0.2 0.0033 18.0 0.2 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) HECT PF00632.25 CBY11471.1 - 1.2e-34 120.2 0.1 1.3e-34 120.1 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 CBY11472.1 - 3.1e-44 151.7 0.1 4.4e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ninjurin PF04923.12 CBY11473.1 - 1.4e-08 34.6 12.0 2.4e-07 30.6 12.0 2.2 1 1 0 1 1 1 1 Ninjurin IQ PF00612.27 CBY11474.1 - 0.0016 18.1 1.0 0.0016 18.1 1.0 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif GOLGA2L5 PF15070.6 CBY11476.1 - 3.4e-17 62.4 2.3 3.9e-17 62.2 2.3 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Macoilin PF09726.9 CBY11476.1 - 0.0032 16.1 3.2 0.0035 16.0 3.2 1.0 1 0 0 1 1 1 1 Macoilin family UPF0242 PF06785.11 CBY11476.1 - 0.032 14.3 7.8 0.052 13.7 7.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 CBY11476.1 - 0.28 11.4 11.0 0.99 9.6 1.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 CBY11476.1 - 0.66 8.8 13.9 0.85 8.4 13.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cgr1 PF03879.14 CBY11476.1 - 0.81 10.1 5.6 3.5 8.1 5.6 1.9 1 1 0 1 1 1 0 Cgr1 family GIT_CC PF16559.5 CBY11476.1 - 0.82 9.6 9.6 0.11 12.4 1.5 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 CBY11476.1 - 1.3 9.6 14.0 0.23 12.0 1.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CBY11476.1 - 1.4 8.7 13.8 0.19 11.5 2.5 2.4 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 CBY11476.1 - 1.7 9.3 8.6 0.72 10.5 1.0 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Ax_dynein_light PF10211.9 CBY11476.1 - 3.5 7.5 12.0 0.62 10.0 5.9 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain HALZ PF02183.18 CBY11476.1 - 5.3 7.3 11.4 6.3 7.1 3.5 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper APG6_N PF17675.1 CBY11476.1 - 5.4 7.6 15.9 14 6.2 15.6 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 CBY11476.1 - 7 7.1 13.2 3.6 8.0 8.4 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GOLGA2L5 PF15070.6 CBY11477.1 - 1.5e-09 37.1 22.4 1.5e-09 37.1 22.4 2.0 1 1 1 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 Med9 PF07544.13 CBY11477.1 - 0.00013 22.0 2.8 0.00013 22.0 2.8 3.9 1 1 3 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 CBY11477.1 - 0.01 15.2 7.3 0.01 15.2 7.3 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fungal_TACC PF12709.7 CBY11477.1 - 0.028 14.9 1.2 0.028 14.9 1.2 3.6 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMF_DNA_bd PF12329.8 CBY11477.1 - 0.037 14.0 30.8 0.25 11.3 7.9 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 CBY11477.1 - 0.1 12.6 34.3 1.3 9.1 10.8 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 CBY11477.1 - 0.14 12.2 0.3 0.14 12.2 0.3 3.4 3 0 0 3 3 3 0 TolA binding protein trimerisation Tropomyosin_1 PF12718.7 CBY11477.1 - 0.44 10.7 35.3 0.035 14.2 13.1 2.3 1 1 0 2 2 2 0 Tropomyosin like Tropomyosin PF00261.20 CBY11477.1 - 0.85 8.9 33.8 0.034 13.5 19.3 2.2 1 1 1 2 2 2 0 Tropomyosin ADIP PF11559.8 CBY11477.1 - 1.3 9.1 37.2 12 5.9 6.4 3.6 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 CBY11477.1 - 1.8 7.9 34.0 0.45 9.9 7.0 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DegS PF05384.11 CBY11477.1 - 1.9 8.0 26.5 0.2 11.1 0.9 3.2 1 1 2 3 3 3 0 Sensor protein DegS DUF1664 PF07889.12 CBY11477.1 - 1.9 8.5 17.7 4.6 7.3 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBY11477.1 - 2.3 7.0 34.2 0.08 11.8 9.9 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein HAP1_N PF04849.13 CBY11477.1 - 3.2 6.9 34.4 1.2 8.3 14.1 2.9 1 1 1 2 2 2 0 HAP1 N-terminal conserved region SlyX PF04102.12 CBY11477.1 - 3.3 8.4 27.4 4.8 7.9 2.2 4.2 2 1 1 4 4 4 0 SlyX YabA PF06156.13 CBY11477.1 - 4 8.1 26.5 1.5 9.5 2.5 3.2 1 1 2 3 3 3 0 Initiation control protein YabA GvpK PF05121.12 CBY11477.1 - 5.9 7.0 14.0 0.62 10.1 0.9 3.4 1 1 1 3 3 3 0 Gas vesicle protein K DUF1515 PF07439.11 CBY11477.1 - 8.6 6.4 12.5 43 4.2 3.3 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) FliJ PF02050.16 CBY11477.1 - 9.8 6.4 30.8 0.43 10.8 9.0 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein Myosin_tail_1 PF01576.19 CBY11478.1 - 0.0028 15.6 66.4 0.0041 15.0 48.2 2.9 1 1 0 2 2 2 2 Myosin tail ZapB PF06005.12 CBY11478.1 - 0.029 14.8 9.0 0.029 14.8 9.0 8.3 3 2 6 9 9 9 0 Cell division protein ZapB WD40_alt PF14077.6 CBY11479.1 - 0.0055 16.5 0.9 0.0055 16.5 0.9 2.3 2 0 0 2 2 2 1 Alternative WD40 repeat motif ABC_tran_CTD PF16326.5 CBY11479.1 - 0.0079 16.4 3.0 0.0079 16.4 3.0 2.4 2 0 0 2 2 2 1 ABC transporter C-terminal domain DUF2443 PF10398.9 CBY11479.1 - 0.013 15.6 2.3 0.056 13.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) AAA_23 PF13476.6 CBY11479.1 - 0.48 10.9 6.7 0.77 10.2 6.6 1.5 1 1 0 1 1 1 0 AAA domain YvrJ PF12841.7 CBY11479.1 - 9.1 5.9 8.0 4.4 6.9 2.1 2.3 2 0 0 2 2 2 0 YvrJ protein family Sec5 PF15469.6 CBY11480.1 - 3.8e-40 137.7 1.8 3.8e-40 137.7 1.8 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.24 CBY11480.1 - 8.8e-10 38.5 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain Roughex PF06020.11 CBY11482.1 - 0.0011 18.1 10.3 0.0015 17.7 10.3 1.2 1 0 0 1 1 1 1 Drosophila roughex protein DUF3006 PF11213.8 CBY11482.1 - 0.044 14.0 0.9 1 9.6 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3006) GREB1 PF15782.5 CBY11482.1 - 0.78 6.8 16.7 1 6.4 16.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Phe_hydrox_dim PF07976.12 CBY11483.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 1 1 2 2 2 0 Phenol hydroxylase, C-terminal dimerisation domain XRN_N PF03159.18 CBY11486.1 - 0.032 13.7 0.0 0.091 12.2 0.0 1.8 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Phage_integrase PF00589.22 CBY11486.1 - 0.096 12.5 1.7 0.53 10.0 0.0 3.1 3 1 0 3 3 3 0 Phage integrase family Arm_vescicular PF18770.1 CBY11487.1 - 5.6e-06 26.2 0.0 0.0031 17.4 0.1 2.8 2 0 0 2 2 2 2 Armadillo tether-repeat of vescicular transport factor TetR_C_27 PF17935.1 CBY11487.1 - 0.059 13.4 0.3 0.18 11.9 0.3 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Fib_alpha PF08702.10 CBY11487.1 - 0.47 10.6 47.1 0.49 10.6 11.8 4.3 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 CBY11487.1 - 2.2 8.5 65.5 0.19 11.9 6.3 5.0 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) Ribosomal_S28e PF01200.18 CBY11488.1 - 7e-34 115.6 0.4 7.7e-34 115.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S4e PF00900.20 CBY11489.1 - 8e-34 115.4 0.1 1.8e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 CBY11489.1 - 4.2e-22 77.5 0.1 6.6e-22 76.9 0.1 1.3 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CBY11489.1 - 1.6e-20 72.9 3.0 3.4e-20 71.9 3.0 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 CBY11489.1 - 2.3e-08 33.6 0.0 5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CBY11489.1 - 0.00024 20.9 2.4 0.0004 20.2 0.0 2.7 3 0 0 3 3 3 1 KOW motif S4_2 PF13275.6 CBY11489.1 - 0.068 13.0 0.2 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 S4 domain Pkinase PF00069.25 CBY11491.1 - 7.8e-75 251.6 0.0 9e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11491.1 - 5e-36 124.3 0.0 1.6e-35 122.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY11491.1 - 9.1e-06 24.8 0.0 5e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY11491.1 - 6.1e-05 22.5 0.0 0.00026 20.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBY11491.1 - 0.0014 18.6 0.0 0.0087 16.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY11491.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RBFA PF02033.18 CBY11491.1 - 0.089 13.3 0.2 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 Ribosome-binding factor A Kdo PF06293.14 CBY11491.1 - 0.092 12.1 0.0 0.3 10.4 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 CBY11492.1 - 4.3e-06 27.1 2.1 3.8e-05 24.1 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY11492.1 - 3.7e-05 23.0 0.0 0.055 13.0 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY11492.1 - 0.0002 21.0 0.1 0.91 9.6 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY11492.1 - 0.066 12.7 0.0 19 5.0 0.1 3.0 2 0 0 2 2 2 0 EF hand Ribosomal_L29e PF01779.17 CBY11492.1 - 0.067 13.5 0.8 0.18 12.2 0.8 1.8 1 0 0 1 1 1 0 Ribosomal L29e protein family LicD PF04991.13 CBY11492.1 - 0.14 12.3 5.1 0.11 12.7 1.6 2.4 1 1 1 2 2 2 0 LicD family bZIP_1 PF00170.21 CBY11496.1 - 2e-05 24.6 7.9 5.9e-05 23.1 7.9 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY11496.1 - 6.3e-05 23.0 6.2 6.3e-05 23.0 6.2 2.3 2 0 0 2 2 2 1 Basic region leucine zipper O-FucT PF10250.9 CBY11497.1 - 1.3e-08 35.0 0.1 3.2e-08 33.7 0.1 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3782 PF12644.7 CBY11497.1 - 0.073 13.2 0.1 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) PhzC-PhzF PF02567.16 CBY11498.1 - 4.9e-53 180.4 0.0 5.6e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Resistin PF06954.11 CBY11498.1 - 0.061 13.9 0.0 0.85 10.2 0.0 2.1 2 0 0 2 2 2 0 Resistin N_NLPC_P60 PF12912.7 CBY11498.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Tsg PF04668.12 CBY11499.1 - 0.0012 19.6 8.1 0.0012 19.6 8.1 1.6 1 1 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region Histone PF00125.24 CBY11500.1 - 4.4e-49 166.2 1.1 4.9e-49 166.0 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CBY11500.1 - 0.0004 21.0 0.8 0.00043 20.9 0.8 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY11500.1 - 0.0005 20.4 0.0 0.00076 19.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBY11500.1 - 0.0011 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBY11500.1 - 0.016 15.4 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sirohm_synth_M PF14824.6 CBY11500.1 - 0.47 10.0 2.3 4.7 6.8 0.4 2.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Ig_3 PF13927.6 CBY11501.1 - 6.3e-11 42.7 0.0 2.2e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CBY11501.1 - 1.3e-09 38.0 0.0 2.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain TSP_1 PF00090.19 CBY11501.1 - 4.2e-09 36.5 2.8 4.2e-09 36.5 2.8 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain Ig_2 PF13895.6 CBY11501.1 - 5e-08 33.2 0.0 1.9e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY11501.1 - 2.1e-07 31.0 0.0 5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CBY11501.1 - 4.5e-05 23.6 0.1 0.31 11.2 0.0 2.5 1 1 1 2 2 2 2 Immunoglobulin V-set domain CarboxypepD_reg PF13620.6 CBY11501.1 - 0.00079 19.7 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 CBY11501.1 - 0.14 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Pro_isomerase PF00160.21 CBY11502.1 - 9.9e-46 155.9 1.0 2e-45 154.9 0.3 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 CBY11502.1 - 0.0051 16.5 23.2 0.0051 16.5 23.2 3.7 1 1 3 4 4 4 1 Nuclear RNA-splicing-associated protein OmpH PF03938.14 CBY11502.1 - 2.2 8.6 15.4 0.98 9.8 1.0 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) EF-hand_4 PF12763.7 CBY11503.1 - 0.0026 17.7 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand NLRC4_HD2 PF17776.1 CBY11503.1 - 0.062 13.8 1.7 0.11 13.1 0.4 2.1 2 0 0 2 2 2 0 NLRC4 helical domain HD2 DUF4045 PF13254.6 CBY11503.1 - 2 8.0 14.0 1.3 8.6 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) USP8_interact PF08941.10 CBY11505.1 - 1.1e-15 57.9 1.7 1.8e-15 57.2 1.7 1.3 1 0 0 1 1 1 1 USP8 interacting zf-C3HC4_2 PF13923.6 CBY11505.1 - 1.5e-10 40.7 6.3 1.5e-10 40.7 6.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY11505.1 - 2.4e-08 34.2 6.4 2.4e-08 34.2 6.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY11505.1 - 6.8e-08 32.3 6.8 6.8e-08 32.3 6.8 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY11505.1 - 1.4e-07 31.2 3.9 1.4e-07 31.2 3.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY11505.1 - 9.6e-07 28.7 7.1 9.6e-07 28.7 7.1 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY11505.1 - 1.8e-06 28.1 9.0 1.8e-06 28.1 9.0 3.0 2 2 1 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY11505.1 - 7.7e-05 22.6 5.8 7.7e-05 22.6 5.8 2.7 2 2 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 CBY11505.1 - 0.00021 21.1 0.6 0.00021 21.1 0.6 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CBY11505.1 - 0.00025 21.1 6.5 0.00025 21.1 6.5 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Sina PF03145.16 CBY11505.1 - 0.00061 19.8 4.0 0.0009 19.2 4.0 1.2 1 0 0 1 1 1 1 Seven in absentia protein family U-box PF04564.15 CBY11505.1 - 0.0012 19.0 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 CBY11505.1 - 0.0017 18.1 1.7 0.0043 16.8 1.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 CBY11505.1 - 0.002 18.2 3.2 0.002 18.2 3.2 2.3 2 2 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CBY11505.1 - 0.0021 17.7 4.3 0.0021 17.7 4.3 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBY11505.1 - 0.0055 16.5 7.6 0.0055 16.5 7.6 2.5 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 TMF_DNA_bd PF12329.8 CBY11505.1 - 0.037 14.0 1.2 0.037 14.0 1.2 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-TRAF PF02176.18 CBY11505.1 - 0.23 12.2 13.4 1.4 9.7 4.3 2.8 1 1 1 2 2 2 0 TRAF-type zinc finger Trm112p PF03966.16 CBY11505.1 - 0.62 10.7 5.7 14 6.3 0.2 3.4 2 2 1 3 3 3 0 Trm112p-like protein zf-RING_4 PF14570.6 CBY11505.1 - 2.4 8.0 17.3 0.94 9.3 8.2 3.0 2 2 1 3 3 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 CBY11505.1 - 2.9 8.2 17.2 2.4 8.4 7.3 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Tubulin PF00091.25 CBY11506.1 - 1.8e-68 230.6 0.0 2.5e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY11506.1 - 2.7e-52 176.2 0.0 4.2e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY11506.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain SNAP PF14938.6 CBY11508.1 - 6e-91 304.8 12.8 6.8e-91 304.6 12.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 CBY11508.1 - 0.0012 18.8 8.1 12 6.3 0.1 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY11508.1 - 0.0022 18.2 9.6 0.37 11.1 1.9 4.0 2 2 1 3 3 3 2 Tetratricopeptide repeat NSF PF02071.20 CBY11508.1 - 0.006 17.1 15.7 9.9 7.4 0.1 7.8 8 1 1 9 9 8 1 Aromatic-di-Alanine (AdAR) repeat SporV_AA PF12164.8 CBY11508.1 - 0.052 13.9 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 Stage V sporulation protein AA TPR_6 PF13174.6 CBY11508.1 - 0.052 14.2 6.6 1.1e+02 3.8 0.1 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF2076 PF09849.9 CBY11508.1 - 0.061 13.4 0.3 0.061 13.4 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Spatacsin_C PF14649.6 CBY11508.1 - 0.11 11.6 6.8 1.2 8.1 5.2 2.7 1 1 1 2 2 2 0 Spatacsin C-terminus MIT PF04212.18 CBY11508.1 - 0.14 12.3 14.8 2.4 8.3 1.3 4.8 3 2 0 4 4 4 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 CBY11508.1 - 3.1 8.1 9.2 3.1 8.1 3.9 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CBY11508.1 - 6.2 6.8 6.6 14 5.7 0.1 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF4201 PF13870.6 CBY11509.1 - 7.7e-22 77.9 24.2 7.7e-22 77.9 24.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) YceG PF02618.16 CBY11509.1 - 1.6 8.2 7.2 0.5 9.9 4.2 1.7 2 0 0 2 2 2 0 YceG-like family Ndufs5 PF10200.9 CBY11509.1 - 1.7 9.0 7.5 0.93 9.8 2.0 2.7 2 2 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PP2C PF00481.21 CBY11510.1 - 2.9e-63 213.9 4.8 1.3e-52 179.0 0.2 2.9 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 CBY11510.1 - 0.00014 21.6 1.3 0.5 10.0 0.0 3.2 3 1 0 3 3 3 2 Protein phosphatase 2C DUF2666 PF10869.8 CBY11510.1 - 0.00029 21.1 2.5 0.0011 19.2 2.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2666) Histone PF00125.24 CBY11511.1 - 1.9e-33 115.6 0.0 3.8e-17 62.9 0.0 2.1 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CBY11511.1 - 7.9e-12 44.7 0.1 2.5e-11 43.1 0.1 1.9 1 0 0 1 1 1 1 C-terminus of histone H2A IMS_C PF11799.8 CBY11511.1 - 0.00051 20.7 0.0 1 10.0 0.0 2.3 2 0 0 2 2 2 2 impB/mucB/samB family C-terminal domain CBFD_NFYB_HMF PF00808.23 CBY11511.1 - 0.002 18.4 0.0 0.082 13.2 0.0 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Vps54 PF07928.12 CBY11511.1 - 0.016 15.6 0.3 7.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Vps54-like protein MAGI_u1 PF16663.5 CBY11511.1 - 0.02 15.0 1.4 5.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Unstructured region on MAGI NCD1 PF04904.13 CBY11511.1 - 0.023 14.7 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) HYR PF02494.16 CBY11511.1 - 0.085 13.2 0.0 22 5.5 0.0 2.3 2 0 0 2 2 2 0 HYR domain TFIID_30kDa PF03540.13 CBY11511.1 - 0.095 12.7 0.0 22 5.1 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Phage_int_SAM_3 PF14659.6 CBY11511.1 - 0.22 11.8 0.3 35 4.8 0.0 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain baeRF_family6 PF18848.1 CBY11511.1 - 0.43 11.0 0.1 0.43 11.0 0.1 2.4 3 0 0 3 3 2 0 Bacterial archaeo-eukaryotic release factor family 6 Glyco_hydro_31 PF01055.26 CBY11512.1 - 1.1e-36 127.0 7.5 1.1e-36 127.0 7.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 DUF3024 PF11225.8 CBY11512.1 - 0.19 12.0 1.7 7.1 7.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3024) MIP PF00230.20 CBY11513.1 - 2.2e-37 129.0 12.0 2.1e-36 125.8 12.0 1.9 1 1 0 1 1 1 1 Major intrinsic protein DUF2254 PF10011.9 CBY11513.1 - 0.0041 16.0 0.3 0.0064 15.4 0.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) PBP PF01161.20 CBY11514.1 - 8.2e-17 61.8 0.0 1.4e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.25 CBY11515.1 - 5.5e-08 32.5 0.2 8.7e-08 31.8 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11515.1 - 0.00098 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase O-FucT PF10250.9 CBY11516.1 - 1.4e-10 41.4 0.3 1.3e-09 38.2 0.3 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cadherin PF00028.17 CBY11517.1 - 8.2e-26 90.3 0.0 1.3e-14 54.3 0.0 2.4 2 1 1 3 3 3 2 Cadherin domain Cadherin_2 PF08266.12 CBY11517.1 - 0.0018 18.1 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Cadherin-like Cadherin_3 PF16184.5 CBY11517.1 - 0.002 18.1 0.1 0.088 12.8 0.0 2.2 2 0 0 2 2 2 1 Cadherin-like DUF4166 PF13761.6 CBY11518.1 - 0.15 11.8 0.0 0.7 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4166) Cadherin_C_2 PF16492.5 CBY11518.1 - 0.27 12.0 1.6 1.8 9.4 1.6 2.2 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Adeno_E3_CR2 PF02439.15 CBY11518.1 - 0.34 10.7 2.8 0.59 9.9 2.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kinocilin PF15033.6 CBY11518.1 - 0.88 9.2 3.8 1.3 8.7 3.3 1.6 1 1 0 1 1 1 0 Kinocilin protein DUF4519 PF15012.6 CBY11518.1 - 5.7 7.2 4.6 4.1 7.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) zf-Di19 PF05605.12 CBY11520.1 - 0.0015 18.8 1.0 0.003 17.8 0.7 1.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CBY11520.1 - 0.036 14.5 1.8 2.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY11520.1 - 0.045 14.1 4.9 1.8 8.9 0.5 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBY11520.1 - 0.048 14.5 2.0 6.1 8.0 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger BLOC1_2 PF10046.9 CBY11520.1 - 0.058 13.7 1.4 16 5.9 0.1 3.4 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF484 PF04340.12 CBY11520.1 - 0.062 13.0 1.4 0.12 12.1 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Myb_DNA-bind_6 PF13921.6 CBY11520.1 - 0.065 13.5 1.2 0.22 11.8 0.2 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain BORCS7 PF16088.5 CBY11520.1 - 0.15 12.3 5.0 6.4 7.1 5.0 2.6 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Jnk-SapK_ap_N PF09744.9 CBY11520.1 - 0.9 9.7 3.8 21 5.3 0.5 2.4 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 WD40 PF00400.32 CBY11521.1 - 1.9e-11 44.3 5.9 0.0032 18.3 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PCI PF01399.27 CBY11522.1 - 3.6e-19 69.2 1.5 3.6e-19 69.2 1.5 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CBY11522.1 - 0.041 14.0 4.1 0.077 13.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY11522.1 - 0.3 11.0 1.3 0.78 9.7 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.21 CBY11523.1 - 2.9e-44 151.6 0.0 4.5e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY11523.1 - 0.00075 19.2 0.3 0.0029 17.3 0.3 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C eIF3_subunit PF08597.10 CBY11523.1 - 0.71 9.7 9.1 1.2 9.0 9.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RRM_1 PF00076.22 CBY11524.1 - 2e-25 88.4 0.0 5.5e-14 51.7 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CBY11524.1 - 1.4e-08 35.7 0.4 1.4e-08 35.7 0.4 3.2 3 2 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein Ndc1_Nup PF09531.10 CBY11524.1 - 7.7 5.1 14.2 9.7 4.7 14.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Myotub-related PF06602.14 CBY11525.1 - 3.8e-86 289.2 0.1 4.6e-86 288.9 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 CBY11525.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBY11525.1 - 0.0088 15.6 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY11525.1 - 0.0099 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Inositol_P PF00459.25 CBY11526.1 - 1.8e-48 165.4 0.0 2.1e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Myotub-related PF06602.14 CBY11527.1 - 4.5e-37 127.8 0.0 6.9e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 CBY11527.1 - 2.5e-07 30.6 0.3 7.2e-07 29.1 0.3 1.8 1 1 0 1 1 1 1 GRAM domain bPH_3 PF14470.6 CBY11527.1 - 0.03 14.7 0.1 0.077 13.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial PH domain ELM2 PF01448.24 CBY11528.1 - 2e-10 41.3 0.3 5.5e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 CBY11528.1 - 8.2e-07 28.8 6.0 0.00072 19.4 0.0 3.2 3 0 0 3 3 3 2 Myb DNA-binding like Myb_DNA-binding PF00249.31 CBY11528.1 - 9.9e-06 25.7 0.0 0.0095 16.1 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY11528.1 - 0.00012 22.3 0.0 0.21 11.9 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain AKNA PF12443.8 CBY11528.1 - 0.049 14.3 0.9 0.12 13.1 0.9 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor DUF1947 PF09183.10 CBY11528.1 - 2.7 8.4 7.0 0.94 9.8 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Glyco_transf_10 PF00852.19 CBY11529.1 - 2.3e-49 167.5 2.2 4.1e-49 166.7 2.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY11529.1 - 1.9e-17 63.7 0.2 6.2e-17 62.1 0.1 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal zinc_ribbon_12 PF11331.8 CBY11529.1 - 0.044 13.6 0.6 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2 PF00096.26 CBY11530.1 - 1.7e-24 84.9 64.9 6e-05 23.3 1.2 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY11530.1 - 2.5e-20 71.4 65.8 0.0019 18.9 1.7 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY11530.1 - 2.4e-19 68.8 57.8 0.00018 21.8 0.1 8.2 7 1 0 7 7 7 7 Zinc-finger double domain zf-C2H2_11 PF16622.5 CBY11530.1 - 1.2e-09 37.8 46.5 8.4e-05 22.2 1.2 8.3 8 0 0 8 8 8 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY11530.1 - 9.8e-06 25.4 12.1 0.0002 21.3 2.6 9.0 9 1 0 9 9 9 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY11530.1 - 6.4e-05 22.6 3.1 6.4e-05 22.6 3.1 7.2 7 0 0 7 7 7 2 C2H2-type zinc-finger domain CpXC PF14353.6 CBY11530.1 - 0.00013 22.0 40.3 0.049 13.7 2.5 6.9 2 2 5 7 7 7 4 CpXC protein zf-C2H2_jaz PF12171.8 CBY11530.1 - 0.00016 21.9 14.0 0.0015 18.7 3.6 7.7 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 CBY11530.1 - 0.00075 19.0 33.3 0.76 9.4 0.4 8.2 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger Spt46 PF17734.1 CBY11530.1 - 0.0012 18.8 1.9 0.0012 18.8 1.9 4.2 2 2 2 4 4 4 1 Spermatogenesis-associated protein 46 zf-met PF12874.7 CBY11530.1 - 0.0041 17.5 1.8 0.0041 17.5 1.8 7.8 8 0 0 8 8 7 3 Zinc-finger of C2H2 type DUF678 PF05077.12 CBY11530.1 - 0.015 15.4 1.7 0.015 15.4 1.7 4.9 4 2 1 5 5 4 0 Protein of unknown function (DUF678) Zn-ribbon_8 PF09723.10 CBY11530.1 - 0.042 14.0 1.4 0.042 14.0 1.4 7.5 6 2 1 7 7 7 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 CBY11530.1 - 0.099 12.6 0.3 0.099 12.6 0.3 7.8 8 1 0 8 8 7 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 CBY11530.1 - 0.22 11.9 42.6 0.67 10.3 6.9 4.6 2 2 2 4 4 4 0 C2H2-type zinc ribbon GAGA PF09237.11 CBY11530.1 - 0.32 10.8 4.6 0.6 10.0 0.1 3.3 3 1 0 3 3 3 0 GAGA factor zinc_ribbon_4 PF13717.6 CBY11530.1 - 0.33 10.9 36.7 1.2 9.2 0.2 7.8 6 2 0 7 7 7 0 zinc-ribbon domain Bowman-Birk_leg PF00228.20 CBY11530.1 - 3.1 8.3 8.4 13 6.3 0.0 3.9 3 2 0 3 3 2 0 Bowman-Birk serine protease inhibitor family ADK_lid PF05191.14 CBY11530.1 - 6 6.9 30.5 2.6 8.1 2.3 6.3 6 1 0 6 6 6 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.6 CBY11530.1 - 9.5 6.1 26.1 3.1 7.6 0.3 5.7 5 0 0 5 5 5 0 zinc-ribbon domain IF4E PF01652.18 CBY11531.1 - 5.2e-44 149.8 0.2 6.2e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Galactosyl_T PF01762.21 CBY11533.1 - 1.5e-19 70.6 0.2 1.9e-19 70.3 0.2 1.2 1 0 0 1 1 1 1 Galactosyltransferase Phage_holin_6_1 PF09682.10 CBY11533.1 - 0.015 15.7 0.1 0.026 15.0 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Glyco_transf_54 PF04666.13 CBY11533.1 - 0.015 14.2 0.4 0.021 13.7 0.4 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Fringe PF02434.16 CBY11533.1 - 0.056 12.9 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Fringe-like PC4 PF02229.16 CBY11533.1 - 0.12 12.0 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Slx4 PF09494.10 CBY11534.1 - 3.8e-13 49.2 0.1 9.4e-13 47.9 0.1 1.7 1 0 0 1 1 1 1 Slx4 endonuclease SAP PF02037.27 CBY11534.1 - 0.092 12.5 0.4 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 SAP domain Prion_bPrPp PF11587.8 CBY11535.1 - 0.18 11.6 0.4 0.45 10.4 0.4 1.6 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal Anticodon_1 PF08264.13 CBY11536.1 - 2.2e-42 144.6 0.0 2.2e-42 144.6 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 CBY11536.1 - 1.4e-20 73.2 0.3 6.4e-12 44.5 0.2 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Val_tRNA-synt_C PF10458.9 CBY11536.1 - 7.5e-05 22.9 4.4 7.5e-05 22.9 4.4 2.6 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm GST_C_3 PF14497.6 CBY11536.1 - 0.00082 19.5 0.2 0.00082 19.5 0.2 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY11536.1 - 0.0011 19.1 0.1 0.0011 19.1 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY11536.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AP1AR PF15745.5 CBY11536.1 - 0.63 9.6 6.0 1.1 8.8 6.0 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein I_LWEQ PF01608.17 CBY11537.1 - 2e-44 151.5 4.8 2e-44 151.5 4.8 4.0 3 1 1 4 4 4 1 I/LWEQ domain ANTH PF07651.16 CBY11537.1 - 2.2e-43 148.3 0.1 2.2e-43 148.3 0.1 2.0 2 0 0 2 2 2 1 ANTH domain FUSC PF04632.12 CBY11537.1 - 6.6 5.1 6.3 11 4.3 0.4 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family Glyco_hydro_9 PF00759.19 CBY11538.1 - 2.5e-138 462.0 5.0 3.4e-138 461.5 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 NPCC PF08058.11 CBY11539.1 - 0.11 12.6 0.3 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Nuclear pore complex component Tctex-1 PF03645.13 CBY11540.1 - 1.2e-11 44.8 0.0 1.3e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family ASC PF00858.24 CBY11541.1 - 1.9e-79 267.7 6.9 1e-77 262.0 6.9 2.0 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel 5_nucleotid PF05761.14 CBY11543.1 - 4e-160 533.7 1.9 4.7e-160 533.4 1.9 1.1 1 0 0 1 1 1 1 5' nucleotidase family LisH_2 PF16045.5 CBY11543.1 - 0.47 9.5 2.3 15 4.7 0.0 3.2 3 0 0 3 3 3 0 LisH Sulfatase PF00884.23 CBY11544.1 - 7.9e-59 199.6 0.1 1e-58 199.2 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY11544.1 - 8.4e-05 22.3 0.4 0.022 14.3 0.4 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 CBY11544.1 - 0.061 14.1 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Glyco_hydro_10 PF00331.20 CBY11545.1 - 6.5e-27 94.5 5.9 1.4e-26 93.5 5.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 CBY11545.1 - 2.8e-10 40.6 13.2 0.0008 19.7 0.6 4.2 3 1 0 3 3 3 3 Carbohydrate binding domain Peptidase_M14 PF00246.24 CBY11546.1 - 2e-77 260.8 1.2 2.8e-77 260.4 1.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY11546.1 - 6.9e-14 52.0 0.6 1.9e-13 50.6 0.5 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide DUF2339 PF10101.9 CBY11547.1 - 0.86 8.1 11.0 0.25 9.9 4.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) Acyl-CoA_dh_1 PF00441.24 CBY11549.1 - 9.2e-30 103.8 0.8 1.4e-29 103.3 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY11549.1 - 3.2e-15 56.1 0.0 6.5e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY11549.1 - 3.5e-09 37.0 0.5 5.3e-09 36.4 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY11549.1 - 0.00046 20.8 0.2 0.0014 19.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Thioredoxin_16 PF18569.1 CBY11550.1 - 0.0066 16.5 0.6 0.016 15.3 0.6 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain DUF2524 PF10732.9 CBY11550.1 - 0.098 13.0 0.1 0.098 13.0 0.1 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF2524) SLATT_6 PF18169.1 CBY11550.1 - 0.13 11.9 15.6 2.1 7.9 0.3 3.6 1 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 HALZ PF02183.18 CBY11550.1 - 0.2 11.9 10.8 0.31 11.3 1.4 3.8 5 0 0 5 5 4 0 Homeobox associated leucine zipper WXG100 PF06013.12 CBY11550.1 - 0.22 11.7 4.3 1.9 8.8 1.5 3.1 4 0 0 4 4 3 0 Proteins of 100 residues with WXG Phage_int_SAM_2 PF12834.7 CBY11550.1 - 0.25 12.0 6.7 15 6.3 2.2 3.3 2 1 1 3 3 3 0 Phage integrase, N-terminal Spc7 PF08317.11 CBY11550.1 - 0.31 9.9 26.8 0.066 12.1 15.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4140 PF13600.6 CBY11550.1 - 0.32 11.4 9.6 1.3 9.5 2.3 3.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PRKG1_interact PF15898.5 CBY11550.1 - 0.52 11.2 22.9 0.89 10.5 8.9 3.5 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 CBY11550.1 - 0.98 9.2 14.1 8.9 6.2 0.1 3.6 2 1 0 2 2 2 0 Septum formation initiator BST2 PF16716.5 CBY11550.1 - 1.1 9.9 15.2 0.11 13.0 5.5 3.5 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 APC_N_CC PF16689.5 CBY11550.1 - 1.8 8.7 7.3 1.6 8.9 2.5 3.0 3 0 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain HIP1_clath_bdg PF16515.5 CBY11550.1 - 2.4 8.8 24.0 2.7 8.6 9.3 3.5 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF883 PF05957.13 CBY11550.1 - 2.6 8.7 7.2 0.46 11.1 1.4 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Med10 PF09748.9 CBY11550.1 - 2.7 8.0 10.9 4.6 7.2 1.2 3.2 2 1 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex Baculo_PEP_C PF04513.12 CBY11550.1 - 2.8 8.0 12.9 3.6 7.6 3.0 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CBY11550.1 - 4.7 7.3 16.8 0.8 9.8 6.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CBY11550.1 - 5.2 7.6 26.4 3.4 8.2 2.8 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region Rootletin PF15035.6 CBY11550.1 - 6.4 6.8 18.9 5.5 7.0 2.3 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HNF-1_N PF04814.13 CBY11551.1 - 4.2e-11 43.8 0.1 4.4e-11 43.8 0.1 1.0 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Collagen PF01391.18 CBY11552.1 - 5.6e-18 64.4 80.6 7.9e-07 28.8 34.8 3.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) OAF PF14941.6 CBY11553.1 - 0.022 14.2 0.1 0.022 14.2 0.1 1.0 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Phospholip_A2_1 PF00068.19 CBY11554.1 - 1.6e-14 54.3 3.2 1.6e-14 54.3 3.2 1.7 2 0 0 2 2 2 1 Phospholipase A2 Helo_like_N PF17111.5 CBY11556.1 - 0.045 13.1 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins AFP_2 PF18815.1 CBY11556.1 - 0.089 13.1 0.2 0.27 11.5 0.2 1.8 1 0 0 1 1 1 0 Bacterial antifreeze protein repeat PRANC PF09372.10 CBY11556.1 - 0.092 13.1 2.4 0.2 12.0 0.6 2.0 2 0 0 2 2 2 0 PRANC domain Mt_ATP-synt_B PF05405.14 CBY11558.1 - 1.9 8.1 5.8 0.45 10.1 2.3 1.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pkinase PF00069.25 CBY11561.1 - 9.3e-59 198.9 0.5 2.1e-45 155.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11561.1 - 1.8e-39 135.6 0.1 1e-26 93.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY11561.1 - 3.3e-09 36.5 0.0 6.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SHQ1 PF04925.15 CBY11561.1 - 0.0017 18.0 2.3 0.81 9.2 0.2 2.3 2 0 0 2 2 2 2 SHQ1 protein SusD_RagB PF07980.11 CBY11561.1 - 0.0053 16.4 0.0 3.4 7.2 0.0 2.1 2 0 0 2 2 2 2 SusD family Cu2_monooxygen PF01082.20 CBY11561.1 - 0.016 15.5 0.1 8.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain CssAB PF16831.5 CBY11561.1 - 0.049 14.0 0.0 13 6.2 0.0 2.5 2 0 0 2 2 2 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 SMC_Nse1 PF07574.13 CBY11561.1 - 0.14 12.0 0.1 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex Haspin_kinase PF12330.8 CBY11561.1 - 0.75 8.7 3.1 7.4 5.4 1.0 2.7 1 1 1 2 2 2 0 Haspin like kinase domain RepA_C PF04796.12 CBY11562.1 - 0.02 14.9 0.9 0.02 14.9 0.9 2.6 1 1 1 2 2 2 0 Plasmid encoded RepA protein CheX PF13690.6 CBY11562.1 - 0.5 10.6 2.2 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 Chemotaxis phosphatase CheX TPH PF13868.6 CBY11562.1 - 2.8 6.4 122.1 0.0031 16.1 92.4 2.9 1 1 1 2 2 2 0 Trichohyalin-plectin-homology domain EGF_CA PF07645.15 CBY11563.1 - 3.7e-10 39.9 8.1 3.7e-10 39.9 8.1 8.4 10 1 0 10 10 10 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY11563.1 - 0.00099 19.3 3.6 0.00099 19.3 3.6 8.9 7 2 1 8 8 8 2 EGF domain hEGF PF12661.7 CBY11563.1 - 0.019 15.6 1.5 0.019 15.6 1.5 9.0 9 2 0 9 9 9 0 Human growth factor-like EGF cEGF PF12662.7 CBY11563.1 - 0.1 12.5 0.2 0.1 12.5 0.2 6.9 6 0 0 6 6 6 0 Complement Clr-like EGF-like Pkinase PF00069.25 CBY11564.1 - 2e-37 129.0 0.0 2.3e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY11564.1 - 6.9e-11 42.0 0.3 4.2e-08 32.9 0.1 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 CBY11564.1 - 6e-08 32.3 0.0 7.2e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY11564.1 - 4.4e-05 22.9 0.0 6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY11564.1 - 8.2e-05 22.6 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY11564.1 - 0.0045 16.6 0.5 0.007 16.0 0.5 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1187 PF06688.11 CBY11564.1 - 0.1 12.9 0.3 0.99 9.8 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1187) TSP_1 PF00090.19 CBY11565.1 - 4.1e-13 49.3 27.6 1.9e-08 34.4 8.6 3.1 2 1 0 2 2 2 2 Thrombospondin type 1 domain TMEM154 PF15102.6 CBY11565.1 - 8.9e-05 22.4 0.2 0.00014 21.8 0.2 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF3439 PF11921.8 CBY11565.1 - 0.0048 16.9 7.5 0.008 16.1 4.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) DUF3377 PF11857.8 CBY11565.1 - 0.024 14.5 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Mucin PF01456.17 CBY11565.1 - 0.024 14.6 9.7 0.046 13.7 9.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2428 PF10350.9 CBY11567.1 - 5.2e-62 209.6 0.1 2e-61 207.7 0.1 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) TAF6_C PF07571.13 CBY11567.1 - 2.5e-05 24.5 0.0 0.022 15.1 0.0 3.5 3 0 0 3 3 3 2 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 CBY11567.1 - 0.00012 22.4 0.1 1.8 9.0 0.0 4.2 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.22 CBY11567.1 - 0.011 15.9 3.1 25 5.5 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat Metallophos PF00149.28 CBY11569.1 - 6.4e-16 59.5 1.5 8.5e-16 59.1 1.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sulfatase PF00884.23 CBY11571.1 - 1.5e-70 238.1 0.0 2e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CBY11571.1 - 2.1e-26 93.1 0.0 3.5e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 CBY11571.1 - 2.6e-08 33.9 0.0 6.9e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Exo_endo_phos PF03372.23 CBY11572.1 - 3.7e-07 29.9 0.0 6.9e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_5 PF07728.14 CBY11572.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_transf_10 PF00852.19 CBY11573.1 - 5.7e-51 172.7 0.1 1.2e-50 171.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY11573.1 - 2.7e-17 63.2 0.0 1.2e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Cu-oxidase_3 PF07732.15 CBY11574.1 - 2.5e-21 75.9 1.0 2.8e-21 75.7 1.0 1.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CBY11575.1 - 6.2e-22 77.8 2.2 9.6e-22 77.2 2.2 1.4 1 1 0 1 1 1 1 Multicopper oxidase TCL1_MTCP1 PF01840.17 CBY11575.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 TCL1/MTCP1 family DUF5080 PF16883.5 CBY11576.1 - 0.086 13.0 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5080) UQ_con PF00179.26 CBY11579.1 - 0.0028 17.3 0.7 0.0032 17.1 0.7 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CBY11579.1 - 0.12 12.2 0.3 0.28 11.1 0.2 1.6 1 1 0 2 2 2 0 UEV domain UQ_con PF00179.26 CBY11580.1 - 0.00024 20.8 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3258 PF11646.8 CBY11580.1 - 0.085 13.0 0.1 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF3258 SRP54 PF00448.22 CBY11581.1 - 3e-74 248.9 1.4 3.4e-74 248.7 0.1 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CBY11581.1 - 5.8e-30 103.8 0.6 5.8e-30 103.8 0.6 3.6 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 CBY11581.1 - 3.6e-18 65.5 1.7 1.2e-17 63.9 1.7 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CBY11581.1 - 2.5e-08 33.7 0.5 1.7e-07 31.0 0.5 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CBY11581.1 - 0.00013 21.0 0.3 0.0038 16.2 0.0 2.8 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CBY11581.1 - 0.00083 19.5 0.0 0.0023 18.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 CBY11581.1 - 0.00093 19.3 0.0 0.007 16.4 0.0 2.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2209 PF09974.9 CBY11581.1 - 0.0034 17.7 0.2 0.0079 16.5 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) SRPRB PF09439.10 CBY11581.1 - 0.0049 16.3 0.1 2.5 7.5 0.0 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit APS_kinase PF01583.20 CBY11581.1 - 0.0058 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP_bind_1 PF03029.17 CBY11581.1 - 0.0086 15.9 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 CBY11581.1 - 0.0095 15.9 0.0 0.096 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CBY11581.1 - 0.014 15.5 0.5 0.072 13.2 0.2 2.4 2 1 0 2 2 1 0 50S ribosome-binding GTPase ResIII PF04851.15 CBY11581.1 - 0.016 15.3 0.2 0.055 13.5 0.2 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CBY11581.1 - 0.028 14.8 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 CBY11581.1 - 0.03 13.9 0.1 0.071 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBY11581.1 - 0.03 14.7 4.0 0.083 13.3 0.7 3.3 3 1 0 3 3 2 0 AAA domain MobB PF03205.14 CBY11581.1 - 0.031 14.2 0.1 0.095 12.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 CBY11581.1 - 0.032 14.6 0.0 0.22 11.9 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CBY11581.1 - 0.044 13.0 0.0 0.093 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 CBY11581.1 - 0.05 13.9 0.1 0.28 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain TK PF00265.18 CBY11581.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase PduV-EutP PF10662.9 CBY11581.1 - 0.093 12.5 0.9 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 CBY11581.1 - 0.12 12.2 0.2 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 CBY11581.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CBY11581.1 - 0.14 11.8 0.1 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.6 CBY11581.1 - 0.21 12.1 0.8 0.77 10.3 0.0 2.4 3 1 0 3 3 2 0 AAA domain CLTH PF10607.9 CBY11581.1 - 1.6 8.6 3.9 3.3 7.6 3.9 1.7 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Peptidase_C12 PF01088.21 CBY11582.1 - 1.7e-55 188.0 0.0 1.9e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Tctex-1 PF03645.13 CBY11583.1 - 4e-19 68.8 0.9 4.9e-19 68.5 0.9 1.0 1 0 0 1 1 1 1 Tctex-1 family Phos_pyr_kin PF08543.12 CBY11583.1 - 0.0063 15.9 0.0 0.0068 15.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Rad60-SLD PF11976.8 CBY11584.1 - 0.037 13.9 0.1 0.9 9.4 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Chitin_synth_1 PF01644.17 CBY11585.1 - 0.02 14.9 0.0 0.02 14.9 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase KORA PF16509.5 CBY11585.1 - 0.021 15.1 0.1 0.026 14.8 0.1 1.2 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Lysozyme_like PF13702.6 CBY11585.1 - 0.079 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Lysozyme-like MOZ_SAS PF01853.18 CBY11586.1 - 5.9e-80 267.1 0.1 9.9e-80 266.4 0.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY11586.1 - 5.1e-21 74.0 3.6 1.4e-20 72.7 3.6 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Linker_histone PF00538.19 CBY11586.1 - 4.1e-07 30.3 0.1 1.4e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family Acetyltransf_7 PF13508.7 CBY11586.1 - 0.0047 17.3 0.0 0.0097 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD PF00628.29 CBY11586.1 - 0.056 13.4 29.0 0.053 13.4 13.5 3.5 2 1 1 3 3 3 0 PHD-finger HTH_IclR PF09339.10 CBY11586.1 - 0.11 12.4 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain C1_1 PF00130.22 CBY11586.1 - 0.38 10.7 22.4 2.8 7.9 1.5 4.3 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NGP1NT PF08153.12 CBY11587.1 - 2.4e-47 160.3 0.4 2.4e-47 160.3 0.4 2.4 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CBY11587.1 - 1.3e-15 57.5 0.0 8.6e-13 48.4 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY11587.1 - 1.6e-06 27.7 0.1 1.1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBY11587.1 - 0.002 18.0 0.8 0.0058 16.5 0.0 2.1 2 1 0 2 2 2 1 RsgA GTPase Arf PF00025.21 CBY11587.1 - 0.01 15.3 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family GLTP PF08718.11 CBY11588.1 - 2.1e-41 141.7 1.5 7e-41 140.0 0.1 2.5 3 0 0 3 3 3 1 Glycolipid transfer protein (GLTP) PH PF00169.29 CBY11588.1 - 2.9e-10 40.6 0.0 1e-09 38.8 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 CBY11588.1 - 6.4e-06 26.4 0.1 1.7e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBY11588.1 - 5.5e-05 23.5 0.4 0.00089 19.6 0.4 3.1 1 1 0 1 1 1 1 Pleckstrin homology domain NGP1NT PF08153.12 CBY11589.1 - 2.4e-47 160.3 0.4 2.4e-47 160.3 0.4 2.5 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CBY11589.1 - 1.3e-15 57.5 0.0 8.6e-13 48.4 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY11589.1 - 1.6e-06 27.7 0.1 1.1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBY11589.1 - 0.002 18.0 0.8 0.0058 16.5 0.0 2.1 2 1 0 2 2 2 1 RsgA GTPase Arf PF00025.21 CBY11589.1 - 0.01 15.3 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family GLTP PF08718.11 CBY11590.1 - 2.9e-39 134.7 0.7 1.5e-38 132.4 0.0 2.4 3 0 0 3 3 3 1 Glycolipid transfer protein (GLTP) PH PF00169.29 CBY11590.1 - 3.9e-10 40.2 0.0 9e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CBY11590.1 - 6.1e-06 26.4 0.1 1.5e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBY11590.1 - 4.6e-05 23.8 0.4 0.00077 19.9 0.4 3.1 1 1 0 1 1 1 1 Pleckstrin homology domain TFIIS_C PF01096.18 CBY11591.1 - 4e-19 68.2 6.4 4e-19 68.2 6.4 2.4 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CBY11591.1 - 6.4e-06 25.9 0.9 1.3e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 CBY11591.1 - 0.014 15.3 3.0 0.046 13.6 0.3 2.5 2 0 0 2 2 2 0 Nudix N-terminal Zn_Tnp_IS1595 PF12760.7 CBY11591.1 - 0.015 15.2 5.2 1.3 9.1 1.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-piccolo PF05715.13 CBY11591.1 - 0.018 15.2 0.8 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger C1_1 PF00130.22 CBY11591.1 - 0.043 13.7 1.8 0.36 10.7 0.2 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.12 CBY11591.1 - 0.16 11.6 4.9 0.7 9.5 0.0 2.6 3 0 0 3 3 3 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 CBY11591.1 - 0.38 10.8 0.0 0.38 10.8 0.0 2.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 CBY11591.1 - 1 9.6 7.1 6.3 7.0 0.5 3.7 4 0 0 4 4 4 0 Zinc ribbon domain HABP4_PAI-RBP1 PF04774.15 CBY11592.1 - 2.8e-14 54.0 13.2 2.8e-14 54.0 13.2 3.9 2 1 1 3 3 3 2 Hyaluronan / mRNA binding family Arv1 PF04161.13 CBY11593.1 - 3.3e-12 47.0 1.9 5.2e-12 46.4 1.6 1.5 1 1 0 1 1 1 1 Arv1-like family zf-HC5HC2H_2 PF13832.6 CBY11594.1 - 1.9e-15 57.0 15.3 3.5e-15 56.1 6.7 3.0 2 1 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 CBY11594.1 - 4.6e-13 48.5 3.6 4.6e-13 48.5 3.6 3.4 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.6 CBY11594.1 - 1.1e-10 41.5 20.9 2.2e-10 40.6 5.6 3.5 2 2 0 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.29 CBY11594.1 - 5.3e-09 35.8 27.9 7.5e-09 35.3 6.0 4.0 4 0 0 4 4 4 2 PHD-finger zf-PHD-like PF15446.6 CBY11594.1 - 0.0028 17.3 2.5 0.0028 17.3 2.5 3.2 2 2 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Nore1-SARAH PF16517.5 CBY11594.1 - 0.004 17.0 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain zf-UDP PF14569.6 CBY11594.1 - 0.0064 16.6 1.4 0.0064 16.6 1.4 2.1 2 0 0 2 2 2 1 Zinc-binding RING-finger Prok-RING_1 PF14446.6 CBY11594.1 - 0.02 14.8 16.8 0.053 13.4 3.5 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 CBY11594.1 - 6.6 7.1 23.6 0.24 11.7 1.8 3.7 3 1 0 3 3 3 0 C1 domain DUF4518 PF15008.6 CBY11595.1 - 0.08 12.1 1.5 0.21 10.8 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Filaggrin PF03516.13 CBY11596.1 - 1.4 9.7 4.3 3.9 8.3 0.1 2.7 2 0 0 2 2 2 0 Filaggrin MSA-2c PF12238.8 CBY11596.1 - 1.9 8.4 5.0 3.5 7.6 5.0 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c RVT_1 PF00078.27 CBY11597.1 - 1.7e-26 93.2 0.0 4.6e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF948 PF06103.11 CBY11598.1 - 0.14 12.5 1.9 0.42 10.9 1.9 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FAM184 PF15665.5 CBY11598.1 - 2.2 8.0 31.9 0.69 9.7 16.1 2.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B PhoU PF01895.19 CBY11598.1 - 3.1 8.3 6.1 1.2 9.6 1.1 2.6 2 0 0 2 2 2 0 PhoU domain RT_RNaseH PF17917.1 CBY11599.1 - 3.6e-29 101.1 0.1 4.2e-28 97.7 0.2 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY11599.1 - 4.2e-26 90.9 0.0 4.3e-25 87.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY11599.1 - 0.0053 16.3 0.1 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L44 PF00935.19 CBY11601.1 - 0.032 14.7 2.3 0.032 14.7 2.3 1.7 2 0 0 2 2 2 0 Ribosomal protein L44 Exo70 PF03081.15 CBY11602.1 - 0.019 14.0 0.8 0.019 14.0 0.8 1.9 2 0 0 2 2 2 0 Exo70 exocyst complex subunit TMIE PF16038.5 CBY11602.1 - 2.1 8.3 4.2 25 4.8 2.0 2.5 2 0 0 2 2 2 0 TMIE protein RVT_1 PF00078.27 CBY11606.1 - 0.01 15.3 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Arteri_nsp7a PF16749.5 CBY11606.1 - 0.025 14.7 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha YlqD PF11068.8 CBY11608.1 - 2.8 8.3 9.6 4.1 7.8 9.6 1.2 1 0 0 1 1 1 0 YlqD protein ZYG-11_interact PF05884.12 CBY11608.1 - 4.9 6.5 5.2 7.8 5.8 5.2 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 rve PF00665.26 CBY11609.1 - 6.4e-08 32.8 0.0 9.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Pox_A32 PF04665.12 CBY11610.1 - 0.013 15.0 1.1 0.17 11.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase PF06745.13 CBY11610.1 - 0.045 13.1 0.2 0.77 9.1 0.0 2.5 3 0 0 3 3 3 0 KaiC TraG-D_C PF12696.7 CBY11610.1 - 0.1 12.6 0.0 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Sigma54_activat PF00158.26 CBY11610.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBY11610.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 CBY11610.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.31 CBY11611.1 - 1.8e-19 70.1 0.6 1.8e-18 66.9 0.0 2.9 3 1 1 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY11611.1 - 1e-14 54.7 0.0 1.1e-12 48.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CBY11611.1 - 5.1e-09 36.7 1.5 2e-08 34.8 1.5 2.1 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 CBY11611.1 - 5.5e-06 26.1 0.0 1.9e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 RQC domain RMI1_C PF16099.5 CBY11611.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold ResIII PF04851.15 CBY11611.1 - 0.00061 19.8 0.5 0.013 15.5 0.0 3.1 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Rsc14 PF08586.10 CBY11611.1 - 0.012 16.5 0.0 0.2 12.5 0.0 2.7 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit TSP_1 PF00090.19 CBY11612.1 - 2e-63 210.4 231.4 2.3e-09 37.3 5.8 17.2 17 3 0 17 17 17 14 Thrombospondin type 1 domain Sulfotransfer_1 PF00685.27 CBY11613.1 - 5.3e-07 29.4 4.5 1.2e-06 28.2 4.5 1.6 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY11613.1 - 0.00068 20.1 0.1 0.0016 18.9 0.1 1.6 1 0 0 1 1 1 1 Sulfotransferase family DUF3456 PF11938.8 CBY11615.1 - 0.00062 20.3 3.9 0.021 15.4 3.9 2.7 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Aldedh PF00171.22 CBY11616.1 - 5.4e-147 490.0 0.0 6.7e-147 489.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GBP PF02263.19 CBY11617.1 - 4.1e-41 140.9 2.1 1.1e-39 136.3 0.1 2.1 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain PP2C_C PF07830.13 CBY11617.1 - 0.023 15.1 1.4 0.43 11.1 0.9 2.6 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Latarcin PF10279.9 CBY11617.1 - 1.3 9.5 0.0 1.3 9.5 0.0 3.4 3 2 0 3 3 3 0 Latarcin precursor NBP1 PF08537.10 CBY11619.1 - 1 8.7 10.3 0.061 12.7 5.3 1.4 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Tetraspanin PF00335.20 CBY11620.1 - 1 9.0 10.8 0.023 14.4 3.2 1.8 2 0 0 2 2 2 0 Tetraspanin family His_Phos_1 PF00300.22 CBY11621.1 - 7.3e-33 113.9 0.0 8.3e-29 100.7 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 CBY11622.1 - 2e-20 72.4 0.2 3.1e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY11622.1 - 4e-06 26.4 0.0 0.068 12.8 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY11622.1 - 1.8e-05 24.5 0.0 0.0048 16.7 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBY11622.1 - 0.066 13.3 0.4 4 7.6 0.1 2.6 2 1 0 2 2 2 0 Limkain b1 PHM7_cyt PF14703.6 CBY11622.1 - 1.1 9.5 6.5 1 9.6 0.5 3.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_L12 PF00542.19 CBY11623.1 - 1.2e-19 70.4 5.9 1.2e-19 70.4 5.9 2.7 2 1 1 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CBY11623.1 - 1.6e-08 34.1 11.7 1.6e-08 34.1 11.7 2.9 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 CBY11623.1 - 8.3 7.1 20.0 0.81 10.3 12.5 2.7 1 1 0 2 2 2 0 60s Acidic ribosomal protein KH_1 PF00013.29 CBY11624.1 - 9.6e-158 512.2 64.5 5.5e-16 58.1 0.3 15.3 15 0 0 15 15 15 15 KH domain KH_2 PF07650.17 CBY11624.1 - 3.8e-18 65.1 52.6 0.03 14.1 0.3 13.5 10 3 3 13 13 13 9 KH domain SLS PF14611.6 CBY11624.1 - 1.2e-14 54.7 24.6 0.047 13.5 0.0 9.3 3 2 5 9 9 9 7 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 CBY11624.1 - 0.00015 21.7 34.0 7.1 6.8 0.1 10.6 10 1 0 11 11 11 3 NusA-like KH domain DUF531 PF04407.12 CBY11624.1 - 0.33 11.0 4.1 5.9 7.0 0.0 4.5 6 1 0 6 6 6 0 Protein of unknown function (DUF531) BMC PF00936.19 CBY11624.1 - 0.41 10.7 10.9 5.7 7.0 0.0 5.9 7 0 0 7 7 7 0 BMC domain Med29 PF11568.8 CBY11625.1 - 1.5e-05 25.2 1.2 4.2e-05 23.8 1.2 1.7 1 1 0 1 1 1 1 Mediator complex subunit 29 CDC14 PF08045.11 CBY11625.1 - 0.042 13.0 0.9 0.052 12.6 0.5 1.3 1 1 0 1 1 1 0 Cell division control protein 14, SIN component TFIIA PF03153.13 CBY11625.1 - 2.9 7.8 20.6 3.1 7.7 20.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3618 PF12277.8 CBY11626.1 - 3.7 7.9 14.3 1.1 9.6 3.7 5.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3618) tRNA_synthFbeta PF17759.1 CBY11627.1 - 0.0056 16.1 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain ABC_trans_N PF14510.6 CBY11627.1 - 0.3 11.7 1.8 1.3 9.7 1.6 2.1 2 0 0 2 2 2 0 ABC-transporter N-terminal NHL PF01436.21 CBY11628.1 - 8.2e-05 22.4 0.1 0.033 14.2 0.0 3.7 4 0 0 4 4 4 2 NHL repeat UPF0086 PF01868.16 CBY11630.1 - 3.8e-20 71.6 0.1 6.2e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF3549 PF12069.8 CBY11630.1 - 0.095 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) IFRD PF05004.13 CBY11630.1 - 0.25 10.4 3.0 0.41 9.7 3.0 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Intein_splicing PF14890.6 CBY11630.1 - 1 9.3 3.4 7.2 6.6 3.4 2.2 1 1 0 1 1 1 0 Intein splicing domain Herpes_LMP1 PF05297.11 CBY11632.1 - 8.3 5.5 10.0 11 5.1 10.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4602 PF15375.6 CBY11633.1 - 7.9e-19 68.3 33.1 3.9e-17 62.8 33.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) HlyD_2 PF12700.7 CBY11636.1 - 0.3 9.8 8.0 0.46 9.2 8.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Complex1_LYR PF05347.15 CBY11637.1 - 0.0051 16.8 1.0 0.0064 16.5 1.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Acyltransferase PF01553.21 CBY11638.1 - 2.4e-09 36.9 0.0 3.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase F-box PF00646.33 CBY11639.1 - 0.00042 20.1 0.1 0.00082 19.2 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CBY11639.1 - 0.0063 16.4 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like Metallophos PF00149.28 CBY11640.1 - 0.00071 20.1 0.1 0.0036 17.8 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Choline_kinase PF01633.20 CBY11641.1 - 1.1e-54 185.3 0.1 2e-54 184.4 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY11641.1 - 1.7e-11 44.5 0.0 3.7e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY11641.1 - 4.7e-05 22.8 0.1 9.2e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase zf-H2C2_2 PF13465.6 CBY11642.1 - 0.0003 21.1 3.5 0.0071 16.7 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY11642.1 - 0.00035 20.9 3.4 0.0027 18.1 0.3 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type Synaptobrevin PF00957.21 CBY11643.1 - 1.4e-27 95.3 1.6 2e-27 94.8 1.6 1.2 1 0 0 1 1 1 1 Synaptobrevin DUF4134 PF13572.6 CBY11643.1 - 0.19 12.0 1.7 0.21 11.9 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Actin PF00022.19 CBY11644.1 - 4.3e-147 490.0 0.0 1.4e-146 488.3 0.0 1.7 1 1 0 1 1 1 1 Actin Mucin PF01456.17 CBY11645.1 - 0.98 9.4 14.4 1.5 8.8 14.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribonuclease_3 PF00636.26 CBY11646.1 - 5.2e-53 178.1 0.0 5.6e-27 94.4 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain PAZ PF02170.22 CBY11646.1 - 2.5e-30 105.1 0.5 3.5e-29 101.4 0.2 3.0 4 0 0 4 4 4 1 PAZ domain Ribonucleas_3_3 PF14622.6 CBY11646.1 - 4.3e-26 91.6 0.9 6.8e-18 65.1 0.0 4.2 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 CBY11646.1 - 3e-20 72.2 0.5 2.6e-19 69.1 0.1 2.9 2 0 0 2 2 2 1 Dicer dimerisation domain dsrm PF00035.26 CBY11646.1 - 7.9e-05 23.3 0.1 0.0088 16.7 0.0 3.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif Helicase_C PF00271.31 CBY11646.1 - 0.00023 21.5 0.0 0.0014 19.0 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ATP_bind_1 PF03029.17 CBY11647.1 - 4e-54 184.0 0.0 4.8e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 CBY11647.1 - 0.00022 20.3 0.0 0.00036 19.6 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 CBY11647.1 - 0.0013 18.9 0.0 0.03 14.4 0.0 2.2 2 1 0 2 2 2 1 Helicase HerA, central domain CLP1_P PF16575.5 CBY11647.1 - 0.0026 17.6 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 CBY11647.1 - 0.024 14.7 0.0 0.085 13.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CBY11647.1 - 0.03 14.9 0.0 0.052 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter KTI12 PF08433.10 CBY11647.1 - 0.035 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 CBY11647.1 - 0.039 14.4 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY11647.1 - 0.04 14.3 0.1 0.1 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBY11647.1 - 0.044 14.1 0.1 0.28 11.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 CBY11647.1 - 0.045 13.9 0.1 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 CBY11647.1 - 0.052 13.7 0.7 0.22 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBY11647.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CBY11647.1 - 0.07 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.7 CBY11647.1 - 0.075 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.12 CBY11647.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CBY11647.1 - 0.13 12.7 0.1 0.58 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBY11647.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY11647.1 - 0.33 11.5 0.0 0.33 11.5 0.0 2.0 2 1 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 CBY11648.1 - 3.7e-54 184.0 0.0 4.5e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 CBY11648.1 - 0.00022 20.3 0.0 0.00036 19.6 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 CBY11648.1 - 0.00056 20.1 0.0 0.03 14.4 0.0 2.2 2 1 0 2 2 2 1 Helicase HerA, central domain CLP1_P PF16575.5 CBY11648.1 - 0.0025 17.6 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 CBY11648.1 - 0.027 14.6 0.0 0.085 13.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CBY11648.1 - 0.028 14.9 0.0 0.052 14.1 0.0 1.6 2 0 0 2 2 1 0 ABC transporter KTI12 PF08433.10 CBY11648.1 - 0.034 13.6 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 CBY11648.1 - 0.037 14.4 0.2 0.11 12.9 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CBY11648.1 - 0.039 14.4 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 CBY11648.1 - 0.045 13.9 0.1 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 CBY11648.1 - 0.046 14.0 0.1 0.28 11.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 CBY11648.1 - 0.049 13.8 0.4 0.22 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBY11648.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CBY11648.1 - 0.069 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.7 CBY11648.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.12 CBY11648.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CBY11648.1 - 0.1 13.0 0.1 0.58 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBY11648.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY11648.1 - 0.33 11.5 0.0 0.33 11.5 0.0 1.9 2 1 0 2 2 1 0 AAA domain COesterase PF00135.28 CBY11650.1 - 2.5e-88 297.2 0.1 3.1e-88 296.9 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY11650.1 - 3.1e-07 30.5 1.7 9.7e-07 28.9 1.7 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY11650.1 - 0.029 13.8 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CBY11650.1 - 0.047 14.3 0.0 0.089 13.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 CBY11650.1 - 0.083 11.7 0.0 0.28 10.0 0.0 1.7 2 0 0 2 2 2 0 Steryl acetyl hydrolase PAM2 PF07145.15 CBY11651.1 - 0.019 14.6 0.1 0.062 13.0 0.1 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region NPV_P10 PF05531.12 CBY11651.1 - 0.18 12.3 1.4 0.42 11.1 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 CBY11651.1 - 0.29 9.0 7.8 0.38 8.6 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 CBY11651.1 - 1.1 7.7 5.6 1.4 7.3 5.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 CBY11651.1 - 1.2 7.7 5.2 1.6 7.2 5.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CorA PF01544.18 CBY11651.1 - 1.9 7.8 9.7 2.6 7.3 9.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein LMBR1 PF04791.16 CBY11651.1 - 2.5 6.9 5.5 3.1 6.6 5.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 CBY11651.1 - 3 8.0 10.8 0.58 10.3 6.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SDP_N PF12278.8 CBY11651.1 - 3.7 7.7 12.2 0.35 11.0 4.4 2.7 1 1 1 2 2 2 0 Sex determination protein N terminal SLATT_5 PF18160.1 CBY11651.1 - 4.3 6.6 5.2 1.1 8.5 1.6 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF572 PF04502.13 CBY11651.1 - 8.8 5.8 18.5 9.7 5.7 17.9 1.2 1 1 0 1 1 1 0 Family of unknown function (DUF572) DUF1542 PF07564.11 CBY11652.1 - 0.0013 18.8 2.5 0.0024 17.9 2.5 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) ABC_trans_N PF14510.6 CBY11652.1 - 2 9.1 4.0 8.3 7.1 0.1 2.7 2 1 1 3 3 3 0 ABC-transporter N-terminal Raffinose_syn PF05691.12 CBY11653.1 - 1.1e-08 33.4 0.0 0.0029 15.5 0.0 2.2 2 0 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 WYL_2 PF10902.8 CBY11653.1 - 0.00032 21.0 0.0 1.9 8.9 0.0 2.8 2 0 0 2 2 2 2 WYL_2, Sm-like SH3 beta-barrel fold HV_small_capsid PF17086.5 CBY11653.1 - 0.075 13.3 0.2 5.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Small capsid protein of Herpesviridae NQRA PF05896.11 CBY11653.1 - 0.083 12.3 0.0 16 4.8 0.0 2.3 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) TPX2 PF06886.11 CBY11653.1 - 5.5 7.3 5.8 28 5.0 0.7 2.4 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Trypsin PF00089.26 CBY11654.1 - 5.9e-31 108.0 2.5 7.4e-31 107.7 2.5 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.15 CBY11654.1 - 0.0043 16.8 0.3 0.006 16.3 0.3 1.2 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Trypsin_2 PF13365.6 CBY11654.1 - 0.0078 17.1 0.0 0.0097 16.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CBY11655.1 - 5.1e-10 39.5 2.8 7e-10 39.1 0.2 2.2 2 1 0 2 2 2 1 Trypsin Sushi PF00084.20 CBY11655.1 - 1.9 9.1 6.9 2.7 8.7 0.4 2.6 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Neur_chan_memb PF02932.16 CBY11656.1 - 9.7e-19 68.4 2.4 8.9e-15 55.4 1.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Tetraspanin PF00335.20 CBY11657.1 - 4.6e-05 23.2 0.8 0.00021 21.1 0.2 1.9 2 0 0 2 2 2 1 Tetraspanin family MRAP PF15183.6 CBY11657.1 - 0.042 13.8 0.3 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Yip1 PF04893.17 CBY11657.1 - 0.054 13.2 2.9 0.077 12.7 0.2 2.0 1 1 1 2 2 2 0 Yip1 domain PMT_4TMC PF16192.5 CBY11657.1 - 0.082 12.5 3.4 4 7.0 0.0 2.1 1 1 1 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase DUF3328 PF11807.8 CBY11657.1 - 0.3 10.8 1.4 3.1 7.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) DUF4131 PF13567.6 CBY11657.1 - 0.52 9.9 4.6 3.4 7.3 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2434 PF10361.9 CBY11657.1 - 0.56 9.1 3.7 2.3 7.1 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2434) ATG27 PF09451.10 CBY11657.1 - 7.7 6.3 5.6 23 4.7 0.4 2.1 1 1 1 2 2 2 0 Autophagy-related protein 27 OPT PF03169.15 CBY11657.1 - 9.4 4.7 8.5 2.6 6.6 1.0 2.0 1 1 1 2 2 2 0 OPT oligopeptide transporter protein Phospholip_A2_1 PF00068.19 CBY11659.1 - 3e-16 59.9 9.5 3.4e-16 59.7 9.5 1.1 1 0 0 1 1 1 1 Phospholipase A2 Peptidase_C107 PF17222.3 CBY11660.1 - 0.04 12.9 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 PDEase_I PF00233.19 CBY11661.1 - 5.2e-70 235.9 3.0 7.2e-70 235.4 3.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase COX7a PF02238.15 CBY11663.1 - 0.026 14.9 4.4 0.7 10.3 1.1 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Ricin_B_lectin PF00652.22 CBY11665.1 - 6e-05 23.3 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CBY11665.1 - 0.029 15.1 0.3 5.2 7.9 0.0 2.5 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like DUF4994 PF16385.5 CBY11669.1 - 0.034 14.0 0.4 0.25 11.3 0.0 2.5 2 2 1 3 3 3 0 Domain of unknown function UCMA PF17085.5 CBY11669.1 - 0.16 12.0 4.6 0.37 10.8 4.6 1.6 1 0 0 1 1 1 0 Unique cartilage matrix associated protein RT_RNaseH_2 PF17919.1 CBY11670.1 - 2.5e-23 82.0 0.0 4e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY11670.1 - 1.5e-22 79.9 0.0 2.4e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY11671.1 - 0.00013 22.0 0.1 0.00037 20.5 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain DPPIV_N PF00930.21 CBY11673.1 - 6e-06 25.2 0.0 1.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region VasI PF11319.8 CBY11674.1 - 0.0043 16.7 0.0 0.0047 16.6 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system VasI, EvfG, VC_A0118 Phospholip_A2_2 PF05826.12 CBY11676.1 - 0.00074 19.7 0.2 2.3 8.5 0.0 2.8 2 0 0 2 2 2 2 Phospholipase A2 Beta_helix PF13229.6 CBY11676.1 - 0.012 15.5 0.2 5 6.9 0.1 2.9 2 0 0 2 2 2 0 Right handed beta helix region Ubiquitin_4 PF18036.1 CBY11676.1 - 0.095 12.8 3.7 2.1 8.5 0.2 3.1 2 0 0 2 2 2 0 Ubiquitin-like domain Snapin_Pallidin PF14712.6 CBY11676.1 - 0.18 12.3 7.0 0.44 11.0 0.3 3.2 3 0 0 3 3 3 0 Snapin/Pallidin IFP_35_N PF07334.13 CBY11676.1 - 0.27 11.3 6.7 2.6 8.2 0.1 3.6 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GIT_CC PF16559.5 CBY11676.1 - 0.56 10.1 9.3 4 7.4 0.6 3.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4699 PF15770.5 CBY11676.1 - 0.68 9.7 12.1 3.4 7.4 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4699) DUF3450 PF11932.8 CBY11676.1 - 2.4 7.4 17.7 0.6 9.4 1.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) FapA PF03961.13 CBY11676.1 - 2.6 6.5 17.6 1.9 7.0 3.6 2.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Laminin_II PF06009.12 CBY11676.1 - 5.9 6.9 14.5 4.8 7.2 1.8 3.0 3 0 0 3 3 3 0 Laminin Domain II ERM PF00769.19 CBY11676.1 - 8.9 6.0 24.4 9.7 5.9 8.1 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Sugar_tr PF00083.24 CBY11677.1 - 1.3e-81 274.8 16.9 1.4e-81 274.7 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY11677.1 - 4.7e-11 42.2 15.1 1.8e-10 40.3 9.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 CBY11677.1 - 8 6.1 6.9 5.1 6.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Gelsolin PF00626.22 CBY11678.1 - 1.3e-50 169.2 0.2 5.7e-14 51.8 0.0 4.2 4 0 0 4 4 4 4 Gelsolin repeat DHC_N2 PF08393.13 CBY11679.1 - 1.3e-22 80.4 0.1 2e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CBY11680.1 - 8.9e-45 153.1 0.0 1.1e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 CBY11680.1 - 7.7e-06 26.4 0.0 1.2e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBY11680.1 - 3e-05 24.0 0.0 0.00055 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBY11680.1 - 0.00044 20.8 0.0 0.00057 20.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBY11680.1 - 0.0036 17.7 0.0 0.0056 17.0 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 CBY11680.1 - 0.0056 16.8 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CBY11680.1 - 0.018 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBY11680.1 - 0.02 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 CBY11680.1 - 0.033 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_30 PF13604.6 CBY11680.1 - 0.041 13.6 0.2 0.055 13.2 0.2 1.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBY11680.1 - 0.045 14.0 0.1 0.072 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY11680.1 - 0.096 13.1 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain CUB PF00431.20 CBY11681.1 - 3.3e-14 53.2 0.2 1.5e-10 41.4 0.1 2.2 1 1 0 2 2 2 2 CUB domain COesterase PF00135.28 CBY11682.1 - 7.9e-22 77.8 0.0 8.8e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY11682.1 - 0.00026 20.9 0.0 0.00026 20.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold EMP24_GP25L PF01105.24 CBY11684.1 - 1.1e-05 25.5 0.1 1.6e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Zona_pellucida PF00100.23 CBY11686.1 - 0.00027 20.8 6.6 0.00037 20.4 6.6 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain SprB PF13573.6 CBY11686.1 - 0.33 10.7 6.5 0.09 12.6 1.2 2.6 2 0 0 2 2 2 0 SprB repeat Cu2_monoox_C PF03712.15 CBY11687.1 - 2.2e-28 98.7 0.7 3.8e-28 98.0 0.7 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 CBY11687.1 - 6.1e-24 84.7 0.0 1.1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Collagen PF01391.18 CBY11688.1 - 1.1e-134 438.2 428.9 2.7e-09 36.6 19.0 17.9 1 1 11 12 12 12 9 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CBY11688.1 - 1.9e-07 30.7 0.0 3.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain SAM_decarbox PF01536.16 CBY11689.1 - 3.1e-108 362.0 0.5 3.5e-108 361.8 0.5 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase A_deaminase PF00962.22 CBY11690.1 - 5.1e-64 216.7 0.0 4.6e-63 213.5 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase Mucin PF01456.17 CBY11691.1 - 0.0067 16.4 25.1 0.016 15.2 25.1 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Kelch_5 PF13854.6 CBY11691.1 - 0.014 15.4 0.4 0.58 10.2 0.0 3.1 3 0 0 3 3 3 0 Kelch motif RIFIN PF02009.16 CBY11691.1 - 0.036 14.0 1.0 0.056 13.3 1.0 1.3 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 CBY11691.1 - 4.1 7.3 9.7 7.3 6.5 9.7 1.4 1 0 0 1 1 1 0 TMEM154 protein family FSA_C PF10479.9 CBY11691.1 - 5.4 5.0 10.7 7.8 4.5 10.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Herpes_UL74 PF07982.12 CBY11691.1 - 6.4 5.6 10.0 9.8 5.0 10.0 1.2 1 0 0 1 1 1 0 Herpes UL74 glycoproteins MGC-24 PF05283.11 CBY11691.1 - 9 6.7 21.9 4.4 7.8 19.1 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LIN37 PF15306.6 CBY11693.1 - 0.39 10.9 2.7 0.62 10.3 2.7 1.3 1 0 0 1 1 1 0 LIN37 Kelch_5 PF13854.6 CBY11694.1 - 0.051 13.6 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Kelch motif HECT PF00632.25 CBY11696.1 - 4.7e-80 269.3 0.1 7.9e-80 268.6 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4093 PF13331.6 CBY11696.1 - 0.061 13.8 0.7 21 5.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4093) IRK_C PF17655.1 CBY11697.1 - 2e-60 203.3 1.4 4.5e-59 199.0 1.4 2.2 1 1 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY11697.1 - 7e-41 139.4 2.3 1.4e-40 138.3 2.3 1.6 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY11697.1 - 0.00016 21.6 4.0 0.00033 20.6 3.8 1.7 1 1 0 1 1 1 1 Ion channel Homeodomain PF00046.29 CBY11700.1 - 0.00026 20.8 0.5 0.00042 20.1 0.5 1.3 1 0 0 1 1 1 1 Homeodomain PARP_reg PF02877.14 CBY11701.1 - 3e-36 124.5 3.7 3.6e-36 124.2 3.7 1.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain DUF1366 PF07104.11 CBY11701.1 - 0.042 13.6 1.9 0.35 10.6 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1366) Kelch_2 PF07646.15 CBY11702.1 - 0.018 15.0 5.6 1.7 8.8 0.0 4.4 4 1 0 4 4 4 0 Kelch motif RHH_4 PF13467.6 CBY11702.1 - 0.036 14.0 0.5 4.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Ribbon-helix-helix domain Kelch_6 PF13964.6 CBY11702.1 - 0.059 13.7 2.6 2.9 8.3 0.0 3.6 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY11702.1 - 0.21 11.6 6.0 0.35 10.9 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 CBY11703.1 - 0.0052 16.7 0.1 1.5 8.9 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY11703.1 - 0.0057 16.9 1.3 0.22 11.9 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY11703.1 - 0.033 14.2 0.0 8.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Astacin PF01400.24 CBY11704.1 - 9e-30 103.7 0.1 1.6e-29 102.9 0.1 1.4 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY11704.1 - 4.9e-05 23.4 7.6 9.2e-05 22.6 7.6 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A cNMP_binding PF00027.29 CBY11705.1 - 1.4e-10 41.1 0.1 3e-07 30.4 0.0 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Phage_T4_Ndd PF06591.11 CBY11705.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Mito_carr PF00153.27 CBY11706.1 - 0.24 11.4 0.0 0.36 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial carrier protein 2OG-FeII_Oxy PF03171.20 CBY11707.1 - 2.7e-10 40.6 0.0 4.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBY11707.1 - 4.2e-05 24.3 0.1 8.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HEPN_LA2681 PF18733.1 CBY11707.1 - 0.00011 21.6 1.6 0.00022 20.6 1.6 1.6 1 1 0 1 1 1 1 LA2681-like HEPN PLAC8 PF04749.17 CBY11708.1 - 2.9e-12 47.4 20.2 3.7e-12 47.1 20.2 1.1 1 0 0 1 1 1 1 PLAC8 family YscO PF07321.12 CBY11709.1 - 0.63 10.0 13.2 0.073 13.0 8.1 1.9 2 0 0 2 2 2 0 Type III secretion protein YscO DUF1963 PF09234.10 CBY11709.1 - 2.1 8.8 6.0 2.7 8.4 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1963) Exonuc_VII_L PF02601.15 CBY11709.1 - 7.5 6.0 9.8 0.36 10.4 4.3 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit RbsD_FucU PF05025.13 CBY11709.1 - 9 6.7 6.4 0.83 10.1 1.0 1.9 3 0 0 3 3 3 0 RbsD / FucU transport protein family DUF1411 PF07199.11 CBY11712.1 - 0.13 11.9 1.4 3.3 7.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) RVT_1 PF00078.27 CBY11713.1 - 8.7e-11 41.8 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 CBY11713.1 - 4.7e-09 36.3 0.0 4.1e-08 33.2 0.0 2.6 2 0 0 2 2 2 1 Phage integrase family ICL PF00463.21 CBY11713.1 - 0.0041 15.7 1.4 0.0075 14.8 1.4 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Dam PF05869.11 CBY11713.1 - 0.066 12.8 0.0 0.27 10.8 0.0 2.0 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Glyco_transf_49 PF13896.6 CBY11715.1 - 2.9e-32 112.4 0.0 4.1e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.6 CBY11716.1 - 4.6e-17 62.4 0.6 4.6e-17 62.4 0.6 1.4 2 0 0 2 2 2 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_5 PF13712.6 CBY11716.1 - 0.068 12.9 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family MAM PF00629.23 CBY11717.1 - 5.6e-06 26.4 0.2 9.3e-06 25.6 0.2 1.4 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu adh_short PF00106.25 CBY11719.1 - 1.2e-35 122.8 0.1 1.4e-35 122.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY11719.1 - 4.2e-22 78.9 0.1 5.5e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 CBY11719.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 CBY11719.1 - 0.0033 17.3 0.0 0.0045 16.9 0.0 1.4 1 1 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.14 CBY11719.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.15 CBY11719.1 - 0.018 14.2 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Metallophos PF00149.28 CBY11721.1 - 4.9e-27 95.8 0.0 9.3e-27 94.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3450 PF11932.8 CBY11722.1 - 0.00098 18.5 8.1 0.0012 18.2 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CCDC144C PF14915.6 CBY11722.1 - 0.0076 15.4 10.0 0.009 15.2 10.0 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region QRPTase_C PF01729.19 CBY11722.1 - 0.008 16.0 2.3 0.0099 15.7 2.3 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain GAS PF13851.6 CBY11722.1 - 0.012 14.9 11.7 0.012 14.9 11.7 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cgr1 PF03879.14 CBY11722.1 - 0.017 15.5 5.8 0.021 15.2 5.8 1.1 1 0 0 1 1 1 0 Cgr1 family Macoilin PF09726.9 CBY11722.1 - 0.02 13.5 6.3 0.022 13.4 6.3 1.0 1 0 0 1 1 1 0 Macoilin family DprA_WH PF17782.1 CBY11722.1 - 0.043 13.9 0.2 0.26 11.4 0.0 2.2 2 1 0 2 2 2 0 DprA winged helix domain FapA PF03961.13 CBY11722.1 - 0.062 11.9 7.6 0.07 11.7 7.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Nup54 PF13874.6 CBY11722.1 - 0.15 12.2 7.5 0.22 11.6 7.5 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1515 PF07439.11 CBY11722.1 - 0.24 11.4 2.5 0.33 11.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Spc29 PF17082.5 CBY11722.1 - 0.25 11.2 6.4 0.35 10.7 6.4 1.4 1 1 0 1 1 1 0 Spindle Pole Component 29 NYD-SP28_assoc PF14775.6 CBY11722.1 - 0.27 11.4 9.4 1.3 9.1 1.7 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain LPP20 PF02169.16 CBY11722.1 - 0.48 10.8 6.9 0.71 10.3 6.9 1.4 1 1 0 1 1 1 0 LPP20 lipoprotein YabA PF06156.13 CBY11722.1 - 0.6 10.8 12.4 1.2 9.8 9.4 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Herpes_BLRF2 PF05812.12 CBY11722.1 - 0.76 9.9 8.4 0.27 11.4 1.9 2.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein APG6_N PF17675.1 CBY11722.1 - 0.93 10.0 11.7 1.6 9.2 11.8 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 CBY11722.1 - 1.8 8.6 8.4 2.4 8.2 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 CBY11722.1 - 3.4 7.8 11.6 2.3 8.4 3.3 2.5 1 1 1 2 2 2 0 bZIP transcription factor DUF3896 PF13035.6 CBY11722.1 - 4.5 7.5 9.8 0.81 9.9 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3896) DivIC PF04977.15 CBY11722.1 - 6.5 6.6 12.5 0.98 9.2 4.8 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 CBY11722.1 - 7.3 6.8 15.2 4 7.6 5.2 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Homeodomain PF00046.29 CBY11724.1 - 2.5e-22 78.5 4.7 5e-22 77.5 4.7 1.5 1 0 0 1 1 1 1 Homeodomain MARVEL PF01284.23 CBY11725.1 - 4.6e-08 33.2 13.0 5.6e-08 32.9 13.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Phage_holin_3_6 PF07332.11 CBY11725.1 - 0.0013 18.7 0.9 0.0013 18.7 0.9 1.9 1 1 1 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III Colicin_V PF02674.16 CBY11725.1 - 0.016 15.1 6.6 0.019 14.9 5.9 1.4 1 1 0 1 1 1 0 Colicin V production protein DUF1211 PF06736.11 CBY11725.1 - 0.24 11.9 3.9 0.44 11.0 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) Gram_pos_anchor PF00746.21 CBY11725.1 - 4.8 7.2 6.4 14 5.7 0.8 2.8 3 0 0 3 3 3 0 LPXTG cell wall anchor motif FixQ PF05545.11 CBY11725.1 - 8.2 6.5 12.1 1.9 8.5 0.2 3.3 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DHFR_1 PF00186.19 CBY11727.1 - 1.3e-05 24.9 0.0 1.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase PIG-P PF08510.12 CBY11727.1 - 0.036 14.0 0.0 0.064 13.2 0.0 1.4 1 1 0 1 1 1 0 PIG-P Gal-3-0_sulfotr PF06990.11 CBY11728.1 - 1.2e-74 251.6 0.5 1.5e-74 251.3 0.5 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY11728.1 - 3.4e-05 23.9 0.4 6.7e-05 22.9 0.4 1.5 1 0 0 1 1 1 1 Sulfotransferase family DUF433 PF04255.14 CBY11730.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Herpes_UL73 PF03554.13 CBY11730.1 - 0.067 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein VEG PF06257.11 CBY11730.1 - 0.25 11.4 1.1 5.2 7.2 0.1 2.3 2 0 0 2 2 2 0 Biofilm formation stimulator VEG PDZ PF00595.24 CBY11731.1 - 3.4e-11 43.3 0.1 6.2e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY11731.1 - 1.1e-06 28.4 0.1 2.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY11731.1 - 0.0064 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.25 CBY11732.1 - 1.9e-37 129.1 0.1 4e-37 128.0 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11732.1 - 1.5e-23 83.4 0.1 1e-22 80.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase UCH PF00443.29 CBY11732.1 - 8.6e-07 28.7 7.3 1.8e-06 27.6 7.3 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Kinase-like PF14531.6 CBY11732.1 - 0.00043 19.7 0.1 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Ribosomal_L29 PF00831.23 CBY11732.1 - 0.095 12.7 3.3 0.071 13.1 0.7 2.3 2 0 0 2 2 2 0 Ribosomal L29 protein DUF2387 PF09526.10 CBY11732.1 - 1 9.6 5.3 16 5.8 0.1 2.8 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Methyltransf_21 PF05050.12 CBY11734.1 - 1.7e-09 38.0 0.0 3.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF3098 PF11297.8 CBY11734.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) Acyl-CoA_dh_1 PF00441.24 CBY11738.1 - 6.1e-41 140.1 9.4 3.3e-36 124.7 3.5 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY11738.1 - 1.7e-24 85.8 0.0 6.2e-24 84.0 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY11738.1 - 6.8e-23 81.5 0.1 2.4e-22 79.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY11738.1 - 2.6e-10 40.7 3.0 3.1e-08 34.0 0.2 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain NUDIX PF00293.28 CBY11739.1 - 9.2e-14 51.6 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain TFIIB PF00382.19 CBY11740.1 - 2.8e-43 145.8 2.8 7.6e-22 77.2 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CBY11740.1 - 2.8e-12 45.9 0.1 5.9e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CBY11740.1 - 7.7e-06 25.7 0.1 0.0079 15.9 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY11740.1 - 0.00012 22.1 0.1 0.37 10.9 0.0 2.4 1 1 1 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 CBY11740.1 - 0.086 12.4 0.1 0.56 9.8 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 RB_B PF01857.20 CBY11740.1 - 0.11 12.5 0.0 0.43 10.6 0.0 1.8 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain DUF2039 PF10217.9 CBY11740.1 - 2.5 8.5 5.2 1.7 9.0 1.6 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) RIO1 PF01163.22 CBY11741.1 - 6.8e-61 205.2 0.0 1.8e-60 203.8 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY11741.1 - 0.00013 22.0 0.0 0.0073 16.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY11741.1 - 0.0041 16.0 0.1 0.0099 14.7 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase UIM PF02809.20 CBY11741.1 - 0.0044 16.8 1.3 0.022 14.7 1.3 2.3 1 0 0 1 1 1 1 Ubiquitin interaction motif RNase_PH PF01138.21 CBY11742.1 - 4.5e-20 72.5 0.0 1e-19 71.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBY11742.1 - 2.8e-12 46.5 0.0 5.1e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NHL PF01436.21 CBY11743.1 - 5.2e-19 67.2 2.3 0.00041 20.2 0.0 6.3 6 0 0 6 6 6 4 NHL repeat SGL PF08450.12 CBY11743.1 - 0.00064 19.4 0.1 0.013 15.1 0.1 2.7 1 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 CBY11743.1 - 0.02 15.0 0.0 1.1 9.4 0.0 3.2 3 0 0 3 3 3 0 Strictosidine synthase RCC1 PF00415.18 CBY11744.1 - 8.8e-72 237.6 19.4 6.6e-13 49.1 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY11744.1 - 1.1e-28 98.3 35.2 4.7e-09 35.8 0.3 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Mucin2_WxxW PF13330.6 CBY11745.1 - 1.7e-18 67.2 0.1 4.4e-16 59.5 0.0 3.4 3 1 0 3 3 3 1 Mucin-2 protein WxxW repeating region Lipocalin PF00061.23 CBY11748.1 - 2.2e-05 24.7 1.3 2.6e-05 24.4 1.3 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Rhamno_transf PF11316.8 CBY11748.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative rhamnosyl transferase Ceramidase PF05875.12 CBY11749.1 - 9.3e-52 176.0 13.5 1.1e-51 175.8 13.5 1.0 1 0 0 1 1 1 1 Ceramidase RCC1 PF00415.18 CBY11750.1 - 4.5e-59 196.9 30.0 2.1e-12 47.4 0.5 8.0 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 CBY11750.1 - 4.4e-57 193.9 0.0 7.7e-57 193.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 CBY11750.1 - 7.7e-25 86.1 34.6 2.3e-09 36.8 1.4 6.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 CBY11750.1 - 0.0051 17.6 2.1 4.1 8.4 0.1 4.5 3 1 0 3 3 3 2 WD domain, G-beta repeat VWA_N2 PF16164.5 CBY11751.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 VWA N-terminal SHNi-TPR PF10516.9 CBY11754.1 - 0.1 12.1 0.3 0.88 9.1 0.1 2.1 2 0 0 2 2 2 0 SHNi-TPR Peptidase_M28 PF04389.17 CBY11757.1 - 1.1e-23 83.9 0.0 1.9e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CBY11757.1 - 1.6e-05 24.9 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CBY11757.1 - 2.2e-05 24.2 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TFR_dimer PF04253.15 CBY11757.1 - 2.8e-05 24.2 0.0 7.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain STG PF15809.5 CBY11758.1 - 0.049 13.7 0.6 0.08 13.0 0.4 1.3 1 1 0 1 1 1 0 Simian taste bud-specific gene product family Kelch_2 PF07646.15 CBY11760.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.6 CBY11760.1 - 0.18 12.2 0.2 0.34 11.3 0.2 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_2 PF07646.15 CBY11761.1 - 3e-08 33.3 2.6 1.5 8.9 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 CBY11761.1 - 1.1e-06 28.5 6.1 0.026 14.5 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 CBY11761.1 - 3.6e-05 23.9 4.2 1 9.7 0.0 5.2 6 0 0 6 6 6 2 Kelch motif PFU PF09070.11 CBY11761.1 - 0.024 14.9 1.4 2.8 8.2 0.3 2.4 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) OAM_dimer PF16554.5 CBY11761.1 - 0.053 14.0 0.0 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Kelch_4 PF13418.6 CBY11761.1 - 0.055 13.5 1.9 37 4.4 0.0 4.6 5 0 0 5 5 5 0 Galactose oxidase, central domain zf-C2H2 PF00096.26 CBY11762.1 - 5.8e-09 35.9 14.4 7.8e-07 29.2 3.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY11762.1 - 1.1e-05 25.6 4.1 1.1e-05 25.6 4.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY11762.1 - 0.0015 18.5 1.8 0.0015 18.5 1.8 3.2 2 1 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 CBY11762.1 - 0.0018 18.6 1.4 0.0018 18.6 1.4 3.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY11762.1 - 0.0032 18.2 15.1 0.0083 16.9 2.6 3.8 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY11762.1 - 0.033 14.5 1.9 0.033 14.5 1.9 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF2682 PF10909.8 CBY11762.1 - 0.065 13.7 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) zf-BED PF02892.15 CBY11762.1 - 2.7 8.1 11.7 0.25 11.4 6.0 2.3 2 0 0 2 2 2 0 BED zinc finger Kelch_4 PF13418.6 CBY11763.1 - 8.1e-05 22.6 0.1 0.44 10.6 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY11763.1 - 0.00017 21.8 0.5 0.2 12.0 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CBY11763.1 - 0.00087 18.8 0.8 0.04 13.5 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CBY11763.1 - 0.0075 16.2 4.8 3.3 7.8 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY11763.1 - 0.0084 16.1 0.1 11 6.2 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Glyco_transf_7N PF13733.6 CBY11764.1 - 2.9e-53 179.1 0.5 3.3e-53 178.9 0.5 1.0 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glycos_transf_2 PF00535.26 CBY11764.1 - 0.077 12.8 0.7 9.5 6.0 0.1 2.3 1 1 0 2 2 2 0 Glycosyl transferase family 2 EGF PF00008.27 CBY11765.1 - 2.6e-48 161.9 185.8 1.5e-07 31.6 9.3 14.7 12 2 2 14 14 14 13 EGF-like domain hEGF PF12661.7 CBY11765.1 - 1.2e-23 82.9 158.9 0.0013 19.3 3.5 15.5 13 1 1 14 14 14 13 Human growth factor-like EGF EGF_2 PF07974.13 CBY11765.1 - 1e-19 70.6 193.9 0.00053 20.3 4.6 13.6 12 1 1 13 13 13 12 EGF-like domain EGF_3 PF12947.7 CBY11765.1 - 1.3e-15 57.2 155.8 0.00055 20.1 3.3 12.7 10 2 2 12 12 12 10 EGF domain Glyco_transf_7C PF02709.14 CBY11765.1 - 3.2e-14 52.3 0.1 6.3e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase FXa_inhibition PF14670.6 CBY11765.1 - 0.0013 19.0 6.9 0.0013 19.0 6.9 13.2 4 3 7 11 11 11 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CBY11765.1 - 0.0029 17.8 11.0 0.0029 17.8 11.0 13.3 1 1 12 13 13 13 4 Calcium-binding EGF domain KH_1 PF00013.29 CBY11766.1 - 4.3e-23 80.9 6.8 1.1e-16 60.4 0.1 4.3 4 0 0 4 4 4 3 KH domain KH_10 PF17905.1 CBY11766.1 - 1.2e-07 32.1 0.1 0.063 13.7 0.0 3.3 3 0 0 3 3 3 2 GLD-3 KH domain 5 Rep_fac-A_3 PF08661.11 CBY11766.1 - 2.8 8.4 5.9 7.6 6.9 0.1 3.4 3 1 1 4 4 4 0 Replication factor A protein 3 Kelch_4 PF13418.6 CBY11767.1 - 1.5e-06 28.1 0.8 0.00011 22.1 0.3 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY11767.1 - 1.6e-05 25.0 3.0 0.015 15.6 0.6 2.6 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CBY11767.1 - 0.028 14.0 4.1 0.25 11.0 1.0 3.2 3 0 0 3 3 3 0 Kelch motif Rol_Rep_N PF18106.1 CBY11768.1 - 0.091 13.1 3.2 0.17 12.2 0.2 2.5 2 0 0 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain MKLP1_Arf_bdg PF16540.5 CBY11768.1 - 0.11 12.6 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 KELK PF15796.5 CBY11769.1 - 0.02 15.3 8.9 0.02 15.3 8.9 4.2 1 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MMR_HSR1_C PF08438.10 CBY11769.1 - 0.037 14.6 4.9 0.11 13.1 4.9 1.9 1 1 0 1 1 1 0 GTPase of unknown function C-terminal Baculo_p24 PF05073.12 CBY11769.1 - 0.49 10.2 10.8 0.29 10.9 8.3 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Exonuc_VII_L PF02601.15 CBY11769.1 - 0.73 9.3 16.1 1 8.9 16.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lectin_N PF03954.14 CBY11769.1 - 7.1 6.4 12.0 2.3 8.0 7.2 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF3450 PF11932.8 CBY11769.1 - 9.5 5.4 23.7 26 4.0 20.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Kelch_6 PF13964.6 CBY11770.1 - 1.1e-05 25.5 6.9 0.19 12.1 0.5 4.0 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 CBY11770.1 - 1.4e-05 25.0 4.3 0.01 15.8 0.4 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY11770.1 - 0.0063 16.1 9.7 1 9.0 1.8 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY11770.1 - 0.22 11.6 4.5 17 5.6 0.3 3.8 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY11771.1 - 3.1e-07 30.3 7.7 0.0044 17.0 0.1 3.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY11771.1 - 2.7e-06 27.4 5.6 0.039 14.3 0.2 3.8 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CBY11771.1 - 3.1e-05 23.5 7.0 0.18 11.4 1.0 4.4 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY11771.1 - 0.074 13.1 4.6 7.6 6.7 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CBY11772.1 - 0.00059 19.7 1.0 3.5 7.8 0.0 4.4 4 1 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY11772.1 - 0.025 14.9 0.2 16 6.0 0.0 3.7 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY11772.1 - 0.52 10.4 2.7 1.9 8.6 0.1 3.1 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY11773.1 - 0.15 12.4 2.7 1.1 9.6 0.0 3.2 2 1 1 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY11773.1 - 0.2 11.7 4.4 1.4 9.0 0.0 3.3 4 0 0 4 4 4 0 Kelch motif ShK PF01549.24 CBY11774.1 - 3.8e-32 110.5 136.4 4.6e-08 33.5 8.6 10.4 10 0 0 10 10 10 9 ShK domain-like TSP_1 PF00090.19 CBY11775.1 - 2e-40 136.8 210.9 1.4e-07 31.6 8.4 15.2 16 0 0 16 16 16 11 Thrombospondin type 1 domain ShK PF01549.24 CBY11775.1 - 7.8e-11 42.3 39.2 6.3e-07 29.8 5.5 13.3 12 0 0 12 12 12 6 ShK domain-like F5_F8_type_C PF00754.25 CBY11775.1 - 0.00014 22.0 0.2 0.003 17.7 0.2 2.7 1 1 0 1 1 1 1 F5/8 type C domain RYDR_ITPR PF01365.21 CBY11776.1 - 4.8e-115 382.1 16.2 1.5e-66 223.7 0.3 3.6 2 0 0 2 2 2 2 RIH domain RyR PF02026.16 CBY11776.1 - 2e-105 345.2 2.8 2.4e-25 88.5 0.0 5.0 4 0 0 4 4 4 4 RyR domain SPRY PF00622.28 CBY11776.1 - 1.1e-54 183.7 7.5 1.6e-22 79.9 0.0 4.1 4 0 0 4 4 4 3 SPRY domain RR_TM4-6 PF06459.12 CBY11776.1 - 7.9e-53 180.1 3.6 9.3e-53 179.9 1.1 2.5 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 Ins145_P3_rec PF08709.11 CBY11776.1 - 9.2e-36 123.0 4.5 8.6e-35 119.9 0.1 3.6 3 1 0 4 4 4 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 CBY11776.1 - 2.4e-34 118.8 0.1 3.4e-32 111.8 0.0 3.1 2 1 1 3 3 3 1 MIR domain RIH_assoc PF08454.11 CBY11776.1 - 4.9e-31 106.6 0.1 4.9e-31 106.6 0.1 4.1 4 0 0 4 4 3 1 RyR and IP3R Homology associated Ion_trans PF00520.31 CBY11776.1 - 1.8e-12 47.0 1.8 1.8e-12 47.0 1.8 2.0 2 0 0 2 2 2 1 Ion transport protein EF-hand_7 PF13499.6 CBY11776.1 - 6.2e-06 26.6 1.1 3e-05 24.4 1.1 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY11776.1 - 0.021 14.7 0.2 0.56 10.1 0.0 2.9 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 CBY11776.1 - 0.08 12.9 0.0 0.34 11.0 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain PRA-PH PF01503.17 CBY11776.1 - 0.12 12.8 0.3 7.7 7.0 0.1 3.0 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Neur_chan_memb PF02932.16 CBY11777.1 - 1.5e-49 169.2 10.4 1.2e-47 163.0 10.4 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY11777.1 - 5.3e-45 153.5 0.0 7.2e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain GST_C_3 PF14497.6 CBY11778.1 - 3.6e-07 30.3 0.0 4.9e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY11778.1 - 0.0058 16.8 0.0 0.0091 16.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY11779.1 - 1.2e-07 31.9 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY11779.1 - 0.11 13.0 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Lipocalin_2 PF08212.12 CBY11780.1 - 3.3e-14 53.0 0.0 4.5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY11780.1 - 6.4e-10 39.4 0.0 9.8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 CBY11780.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Triabin CYYR1 PF10873.8 CBY11781.1 - 0.095 13.1 10.4 0.19 12.2 10.3 1.5 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Molybdopterin PF00384.22 CBY11782.1 - 2.7e-61 207.8 0.0 7.3e-60 203.1 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CBY11782.1 - 1.5e-20 73.0 0.5 3e-20 72.0 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 CBY11782.1 - 5.7e-17 61.0 0.3 5.7e-17 61.0 0.3 2.1 3 0 0 3 3 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 CBY11782.1 - 6e-10 38.9 0.6 6e-10 38.9 0.6 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 CBY11782.1 - 4.4e-08 33.7 0.0 1.1e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer4 PF00037.27 CBY11782.1 - 0.014 15.2 5.1 0.75 9.7 1.9 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Lyx_isomer PF07385.12 CBY11782.1 - 0.031 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase Fer4_16 PF13484.6 CBY11782.1 - 0.05 14.5 3.0 18 6.4 2.6 3.0 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CBY11782.1 - 0.36 11.0 5.4 1.9 8.7 5.4 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBY11782.1 - 0.41 11.3 6.1 0.54 10.9 3.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 CBY11782.1 - 5.4 7.5 8.5 21 5.7 8.5 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBY11782.1 - 7.4 7.3 10.0 1 10.0 3.1 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBY11782.1 - 9.3 6.9 8.9 0.84 10.2 3.3 2.2 2 0 0 2 2 1 0 4Fe-4S dicluster domain TPR_2 PF07719.17 CBY11783.1 - 7.1e-12 44.5 10.8 0.0082 16.2 0.5 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY11783.1 - 2.8e-08 33.9 0.2 0.31 12.0 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat Ank PF00023.30 CBY11783.1 - 9.3e-07 29.0 0.1 1.8e-05 25.0 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 CBY11783.1 - 4.9e-06 27.1 0.0 3.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) TPR_8 PF13181.6 CBY11783.1 - 2.7e-05 24.0 4.3 0.37 11.1 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY11783.1 - 6.1e-05 23.2 15.9 0.039 14.3 1.6 5.4 5 1 0 6 6 6 1 Tetratricopeptide repeat Ank_3 PF13606.6 CBY11783.1 - 7.3e-05 22.9 0.1 0.00059 20.1 0.0 2.7 3 0 0 3 3 1 1 Ankyrin repeat TPR_1 PF00515.28 CBY11783.1 - 0.00011 21.8 14.3 4.1 7.4 0.5 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat Ank_4 PF13637.6 CBY11783.1 - 0.001 19.6 0.0 1 10.0 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY11783.1 - 0.0012 19.1 0.1 0.053 13.9 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TPR_6 PF13174.6 CBY11783.1 - 0.0048 17.4 2.1 6.7 7.6 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY11783.1 - 0.034 14.0 6.9 1.2 9.1 0.4 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY11783.1 - 0.04 14.6 5.6 41 4.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat LTXXQ PF07813.12 CBY11783.1 - 0.14 12.9 7.4 14 6.5 0.0 4.4 4 0 0 4 4 3 0 LTXXQ motif family protein TPR_7 PF13176.6 CBY11783.1 - 0.24 11.5 4.6 23 5.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY11783.1 - 0.25 11.0 4.2 7.6 6.3 0.2 4.4 4 0 0 4 4 4 0 TPR repeat LRR_8 PF13855.6 CBY11783.1 - 1.2 8.9 25.4 1.6 8.6 0.2 5.9 3 2 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 CBY11783.1 - 3 8.4 25.1 2.4 8.7 0.2 5.2 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) Alg6_Alg8 PF03155.15 CBY11785.1 - 4.7e-121 405.1 18.9 6e-121 404.8 18.9 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TMEM61 PF15105.6 CBY11785.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 TMEM61 protein family Erf4 PF10256.9 CBY11786.1 - 1.7e-10 41.0 0.0 2.4e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family V-SNARE_C PF12352.8 CBY11787.1 - 5.3e-11 42.6 1.0 1.2e-10 41.6 1.0 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CBY11787.1 - 0.044 14.2 0.9 0.13 12.6 0.0 2.2 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spc7 PF08317.11 CBY11787.1 - 0.41 9.5 3.3 1.8 7.4 0.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Acyl-CoA_dh_1 PF00441.24 CBY11788.1 - 6.6e-38 130.3 0.2 1e-37 129.6 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY11788.1 - 3.3e-28 98.6 0.0 6.2e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY11788.1 - 1.8e-27 95.4 0.0 3.5e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY11788.1 - 4.7e-09 36.6 0.0 6.8e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2627 PF11118.8 CBY11789.1 - 0.23 12.1 1.9 0.23 12.1 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) MFS_1 PF07690.16 CBY11790.1 - 9.4e-06 24.8 8.3 1.2e-05 24.4 8.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1686 PF07937.11 CBY11790.1 - 0.049 13.5 0.3 0.085 12.7 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1686) Ifi-6-16 PF06140.13 CBY11791.1 - 1.8e-09 37.4 21.9 3.2e-09 36.6 21.9 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family zf-C2H2 PF00096.26 CBY11792.1 - 8.5e-18 63.7 29.8 8e-06 26.0 1.3 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY11792.1 - 5.5e-17 61.3 35.7 5.1e-10 39.3 0.9 5.6 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY11792.1 - 3.6e-12 46.0 24.7 2.1e-05 24.9 0.8 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY11792.1 - 7e-06 26.2 13.9 0.0056 16.9 1.1 4.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 CBY11792.1 - 1.2e-05 25.3 11.8 2.1 8.5 0.5 4.6 4 0 0 4 4 4 3 Zinc ribbon domain zf-met PF12874.7 CBY11792.1 - 9.6e-05 22.6 23.1 0.037 14.4 1.9 4.4 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf_UBZ PF18439.1 CBY11792.1 - 0.0044 16.6 14.6 0.32 10.6 2.0 4.4 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 CBY11792.1 - 0.035 14.1 1.1 0.035 14.1 1.1 4.1 4 0 0 4 4 3 0 C2H2-type zinc finger C1_1 PF00130.22 CBY11792.1 - 0.05 13.5 12.8 1.9 8.5 6.5 3.4 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_3rep PF18868.1 CBY11792.1 - 0.093 13.4 19.1 0.26 12.0 0.7 3.7 3 2 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 CBY11792.1 - 0.14 11.9 18.6 1.4 8.7 1.1 4.0 4 0 0 4 4 3 0 zinc-finger C2H2-type XPA_N PF01286.18 CBY11792.1 - 0.18 11.9 13.6 1.2 9.3 0.6 4.4 4 0 0 4 4 4 0 XPA protein N-terminal zf-H2C2_5 PF13909.6 CBY11792.1 - 0.18 11.6 0.1 0.18 11.6 0.1 4.3 4 0 0 4 4 3 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 CBY11792.1 - 0.28 12.0 17.9 0.09 13.5 2.5 3.0 2 1 1 3 3 2 0 zinc-ribbon family Prok-RING_1 PF14446.6 CBY11792.1 - 0.36 10.8 14.3 3.8 7.5 0.2 4.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.7 CBY11792.1 - 0.63 10.4 15.6 17 5.8 0.9 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 CBY11792.1 - 1 9.4 12.1 59 3.8 0.1 3.5 2 1 0 2 2 2 0 Adenylate kinase, active site lid PyrI_C PF02748.15 CBY11792.1 - 1.2 9.0 16.8 4.6 7.2 0.2 4.4 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.6 CBY11792.1 - 1.7 8.6 6.9 20 5.2 0.1 3.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Rpr2 PF04032.16 CBY11792.1 - 4.3 7.7 13.9 0.71 10.2 3.1 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-trcl PF13451.6 CBY11792.1 - 6.9 6.7 14.9 18 5.3 0.2 4.2 4 0 0 4 4 4 0 Probable zinc-ribbon domain DUF2225 PF09986.9 CBY11792.1 - 7.9 6.1 13.4 20 4.8 2.6 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) C1_2 PF03107.16 CBY11792.1 - 9.5 6.6 23.5 8.8 6.7 9.5 4.2 2 1 1 3 3 3 0 C1 domain VWA PF00092.28 CBY11793.1 - 9.9e-19 68.2 4.5 2.2e-10 41.0 0.9 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Collagen PF01391.18 CBY11793.1 - 5.3e-17 61.3 65.3 6.4e-08 32.2 21.5 3.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 CBY11793.1 - 1.3e-06 29.0 0.1 0.0064 17.1 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain SOGA PF11365.8 CBY11793.1 - 0.11 13.6 0.0 0.49 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein SOGA Pkinase PF00069.25 CBY11794.1 - 2e-45 155.2 0.0 2.7e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11794.1 - 8.6e-28 97.3 0.0 1.1e-27 97.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY11794.1 - 0.049 13.0 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ASH PF15780.5 CBY11796.1 - 1.7e-13 50.6 0.0 3.7e-10 39.9 0.0 2.6 2 1 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Phage_Mu_Gam PF07352.12 CBY11797.1 - 0.0048 16.8 0.3 0.0053 16.7 0.3 1.1 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein vATP-synt_E PF01991.18 CBY11797.1 - 0.0058 16.1 0.3 0.0063 15.9 0.3 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit TM1586_NiRdase PF14512.6 CBY11797.1 - 0.014 15.0 0.9 0.017 14.7 0.9 1.1 1 0 0 1 1 1 0 Putative TM nitroreductase Uds1 PF15456.6 CBY11797.1 - 0.016 15.4 0.3 0.025 14.8 0.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DUF2039 PF10217.9 CBY11797.1 - 0.021 15.2 0.6 0.031 14.6 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) FH2 PF02181.23 CBY11797.1 - 0.021 14.0 0.5 0.026 13.6 0.5 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Peptidase_M19 PF01244.21 CBY11797.1 - 0.04 13.1 0.2 0.041 13.1 0.2 1.0 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Cut12 PF11500.8 CBY11797.1 - 0.057 13.4 2.5 0.14 12.1 2.5 1.7 1 1 0 1 1 1 0 Spindle pole body formation-associated protein PAN_1 PF00024.26 CBY11798.1 - 5.9e-16 58.2 10.8 5.5e-05 23.1 0.8 3.5 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 CBY11798.1 - 7.5e-06 25.8 10.5 0.0069 16.3 0.1 3.5 3 0 0 3 3 3 3 PAN domain DUF1759 PF03564.15 CBY11798.1 - 0.067 13.1 1.0 0.12 12.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) YebO PF13974.6 CBY11798.1 - 0.4 10.8 5.6 1.1 9.4 5.6 1.7 1 0 0 1 1 1 0 YebO-like protein FUSC PF04632.12 CBY11798.1 - 5.2 5.5 6.3 7 5.1 6.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CBM_14 PF01607.24 CBY11799.1 - 3.6e-11 43.1 5.2 3.6e-11 43.1 5.2 1.4 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Histone PF00125.24 CBY11800.1 - 0.042 14.2 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Squash PF00299.18 CBY11800.1 - 0.57 10.3 2.3 2.2 8.4 0.9 2.2 2 0 0 2 2 2 0 Squash family serine protease inhibitor Lectin_C PF00059.21 CBY11801.1 - 1e-40 138.8 18.1 1.9e-16 60.7 0.8 3.7 4 0 0 4 4 4 3 Lectin C-type domain Trefoil PF00088.18 CBY11801.1 - 1.6e-08 34.3 4.5 4.3e-08 32.9 4.5 1.8 1 0 0 1 1 1 1 Trefoil (P-type) domain RE_CfrBI PF09516.10 CBY11802.1 - 0.047 13.1 0.1 0.056 12.9 0.1 1.1 1 0 0 1 1 1 0 CfrBI restriction endonuclease EF-hand_14 PF17959.1 CBY11802.1 - 0.095 13.1 0.7 0.58 10.5 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain HR1 PF02185.16 CBY11802.1 - 1 9.5 8.1 0.36 11.0 5.2 1.6 2 0 0 2 2 2 0 Hr1 repeat Pkinase PF00069.25 CBY11803.1 - 3.6e-19 69.1 0.0 7.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11803.1 - 1.4e-08 34.3 0.1 3.7e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 CBY11803.1 - 2.9e-06 27.3 0.9 7.4e-06 25.9 0.9 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 APH PF01636.23 CBY11803.1 - 0.0031 17.5 0.0 0.0071 16.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Neur_chan_LBD PF02931.23 CBY11804.1 - 1.4e-66 224.0 4.6 1.8e-66 223.7 4.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY11804.1 - 1.5e-30 107.0 12.8 2.3e-30 106.4 12.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 CBY11804.1 - 0.11 11.9 7.0 0.23 10.8 7.0 1.5 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Glyco_hydro_20 PF00728.22 CBY11805.1 - 2.6e-69 234.3 0.4 3.7e-69 233.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF3805 PF12712.7 CBY11805.1 - 1.2 9.3 5.1 0.85 9.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3805) SET PF00856.28 CBY11806.1 - 8.8e-14 52.2 0.3 2.4e-10 41.1 0.1 3.1 3 0 0 3 3 3 2 SET domain DUF3390 PF11870.8 CBY11806.1 - 0.034 14.5 0.0 1.1 9.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3390) CRM1_C PF08767.11 CBY11807.1 - 0.0024 17.1 0.2 0.004 16.4 0.2 1.2 1 0 0 1 1 1 1 CRM1 C terminal RVT_1 PF00078.27 CBY11808.1 - 3.5e-28 98.7 0.0 8.2e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cep57_MT_bd PF06657.13 CBY11808.1 - 0.29 11.6 2.8 2.5 8.6 0.1 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF725 PF05267.12 CBY11809.1 - 0.26 11.3 2.5 13 5.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF725) Aminotran_1_2 PF00155.21 CBY11810.1 - 3.7e-28 98.7 0.0 4.2e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tyr-DNA_phospho PF06087.12 CBY11811.1 - 1.9e-98 330.2 0.3 2.5e-98 329.8 0.3 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCHH PF10283.9 CBY11811.1 - 4e-09 36.3 2.6 7.1e-09 35.5 2.6 1.4 1 0 0 1 1 1 1 PBZ domain AAA PF00004.29 CBY11812.1 - 1.1e-38 132.6 0.0 9.2e-38 129.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY11812.1 - 5.7e-09 35.7 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBY11812.1 - 3.8e-06 26.8 0.0 1.2e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 CBY11812.1 - 7.4e-06 26.0 0.1 7.1e-05 22.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBY11812.1 - 7.6e-05 22.5 0.0 0.00018 21.3 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 CBY11812.1 - 0.00015 21.2 0.0 0.12 11.7 0.0 2.4 1 1 1 2 2 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 CBY11812.1 - 0.00047 19.6 0.1 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CBY11812.1 - 0.00075 18.8 1.3 0.00076 18.8 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 CBY11812.1 - 0.0012 19.0 0.1 0.01 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBY11812.1 - 0.0019 18.6 0.0 0.028 14.8 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBY11812.1 - 0.0023 18.2 0.0 0.065 13.5 0.0 2.6 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBY11812.1 - 0.0054 17.1 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CBY11812.1 - 0.0081 16.2 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 CBY11812.1 - 0.0098 15.3 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 CBY11812.1 - 0.011 15.3 0.1 0.099 12.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CBY11812.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Rsbr_N PF08678.10 CBY11812.1 - 0.029 14.4 0.1 12 5.9 0.0 2.8 2 0 0 2 2 2 0 Rsbr N terminal AAA_24 PF13479.6 CBY11812.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY11812.1 - 0.048 13.2 0.0 0.15 11.5 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CBY11812.1 - 0.079 13.5 0.4 0.21 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 CBY11812.1 - 0.13 12.4 0.0 0.88 9.7 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 CBY11812.1 - 0.18 11.2 1.5 0.49 9.8 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein PQ-loop PF04193.14 CBY11813.1 - 4.4e-36 122.5 6.2 6.3e-19 67.5 2.0 2.6 2 0 0 2 2 2 2 PQ loop repeat LtrA PF06772.11 CBY11813.1 - 0.00095 18.5 2.7 0.0019 17.5 2.7 1.4 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Gal4_dimer PF03902.13 CBY11815.1 - 0.036 14.2 0.2 0.28 11.4 0.1 2.4 2 0 0 2 2 2 0 Gal4-like dimerisation domain Pkinase_Tyr PF07714.17 CBY11816.1 - 4.5e-63 212.9 0.0 8.6e-63 212.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY11816.1 - 4.6e-39 134.4 0.0 9.2e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Glyco_tranf_2_3 PF13641.6 CBY11816.1 - 1.2e-20 74.4 0.0 2.4e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY11816.1 - 1.7e-16 60.8 1.5 1.7e-16 60.8 1.5 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_hydro_6 PF01341.17 CBY11816.1 - 3.6e-15 56.5 0.0 2.1e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Glycos_transf_2 PF00535.26 CBY11816.1 - 4.2e-14 52.7 0.0 8.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CBY11816.1 - 5.6e-08 32.5 0.0 9.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 CBY11816.1 - 6.5e-08 31.6 7.6 0.00018 20.2 5.1 2.3 1 1 1 2 2 2 2 Cellulose synthase Toxin_YhaV PF11663.8 CBY11816.1 - 0.024 14.7 0.2 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system Kinase-like PF14531.6 CBY11816.1 - 0.16 11.2 0.0 0.41 9.9 0.0 1.6 1 0 0 1 1 1 0 Kinase-like SF-assemblin PF06705.11 CBY11817.1 - 0.0014 18.1 4.2 0.0017 17.8 4.2 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin Apolipoprotein PF01442.18 CBY11817.1 - 0.0057 16.6 6.4 0.012 15.5 6.4 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Leu_zip PF15294.6 CBY11817.1 - 0.011 15.3 8.4 0.015 14.8 8.4 1.3 1 0 0 1 1 1 0 Leucine zipper ZYG-11_interact PF05884.12 CBY11817.1 - 0.014 14.8 1.2 0.017 14.6 1.2 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 V-ATPase_G PF03179.15 CBY11817.1 - 0.017 15.6 7.1 0.017 15.6 7.1 1.7 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Wtap PF17098.5 CBY11817.1 - 0.053 13.5 1.9 0.061 13.3 0.3 1.7 1 1 1 2 2 2 0 WTAP/Mum2p family HSCB_C PF07743.13 CBY11817.1 - 0.056 13.9 0.3 0.056 13.9 0.3 2.4 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain LIN37 PF15306.6 CBY11817.1 - 0.059 13.6 2.3 0.068 13.4 2.3 1.1 1 0 0 1 1 1 0 LIN37 Mto2_bdg PF12808.7 CBY11817.1 - 0.065 13.5 1.7 0.16 12.3 1.7 1.7 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RRF PF01765.19 CBY11817.1 - 0.074 13.0 7.0 0.091 12.7 6.3 1.5 1 1 0 1 1 1 0 Ribosome recycling factor Gp-FAR-1 PF05823.12 CBY11817.1 - 0.18 12.1 7.2 0.043 14.2 3.1 2.0 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DivIVA PF05103.13 CBY11817.1 - 0.46 10.6 11.3 34 4.5 11.3 3.0 1 1 0 1 1 1 0 DivIVA protein Phasin PF05597.11 CBY11817.1 - 0.55 10.2 4.9 0.096 12.7 1.5 1.5 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Phage_Mu_Gam PF07352.12 CBY11817.1 - 1 9.3 9.1 1.5 8.7 2.0 2.7 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein TMPIT PF07851.13 CBY11817.1 - 1.1 8.5 6.9 1.2 8.3 6.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF883 PF05957.13 CBY11817.1 - 1.7 9.3 4.3 0.45 11.1 1.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) NYD-SP28_assoc PF14775.6 CBY11817.1 - 2.4 8.3 5.6 0.45 10.7 1.0 2.1 3 1 0 3 3 2 0 Sperm tail C-terminal domain ZapB PF06005.12 CBY11817.1 - 8.3 6.9 9.6 3.3e+02 1.8 9.6 2.6 1 1 0 1 1 1 0 Cell division protein ZapB EF-hand_8 PF13833.6 CBY11818.1 - 3.2e-08 33.3 8.3 1.3e-07 31.4 4.2 3.5 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 CBY11818.1 - 4.5e-08 33.4 7.0 1.9e-07 31.4 3.7 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY11818.1 - 5.7e-08 31.8 14.2 0.00018 20.8 2.6 4.2 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY11818.1 - 2.6e-07 30.0 7.1 0.0028 17.5 0.5 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY11818.1 - 3.4e-05 23.1 9.9 0.0025 17.3 1.9 3.5 4 0 0 4 4 4 2 EF hand DUF3884 PF13024.6 CBY11818.1 - 0.027 14.0 0.1 0.15 11.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3884) EF-hand_4 PF12763.7 CBY11818.1 - 0.041 13.8 2.1 0.057 13.4 1.0 1.9 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBY11818.1 - 0.18 12.7 0.5 0.43 11.5 0.3 1.7 2 0 0 2 2 2 0 EF-hand domain GTP_EFTU PF00009.27 CBY11820.1 - 9.7e-33 113.3 4.6 1.3e-30 106.4 3.8 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CBY11820.1 - 5.1e-23 81.2 2.7 2.4e-22 79.0 2.2 2.4 3 0 0 3 3 3 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CBY11820.1 - 8.6e-10 38.7 0.2 3.7e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBY11820.1 - 6e-07 29.3 0.1 1.7e-06 27.9 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 CBY11820.1 - 9.7e-06 25.6 0.1 0.006 16.5 0.0 2.6 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CBY11820.1 - 0.00019 20.9 0.0 0.0004 19.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBY11820.1 - 0.00019 21.0 0.0 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 CBY11820.1 - 0.0034 16.9 0.0 0.021 14.4 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Nop52 PF05997.12 CBY11822.1 - 5.6e-50 170.1 0.1 6.5e-50 169.9 0.1 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DNA_pol_D_N PF18018.1 CBY11823.1 - 9.8e-27 93.6 0.1 1.4e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 CBY11824.1 - 1.8e-14 53.6 0.0 2.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SQS_PSY PF00494.19 CBY11825.1 - 8.7e-30 104.1 0.3 1.1e-29 103.8 0.3 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase C5-epim_C PF06662.13 CBY11825.1 - 0.042 13.3 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Cupredoxin_1 PF13473.6 CBY11827.1 - 0.31 11.2 3.6 0.25 11.5 0.5 2.5 1 1 0 2 2 2 0 Cupredoxin-like domain Monooxygenase_B PF04744.12 CBY11827.1 - 2.2 7.0 5.3 0.4 9.5 2.2 1.4 2 0 0 2 2 2 0 Monooxygenase subunit B protein L_HMGIC_fpl PF10242.9 CBY11828.1 - 0.00085 19.6 1.9 0.00085 19.6 1.9 2.3 1 1 2 3 3 3 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 CBY11828.1 - 0.004 17.1 13.8 0.014 15.3 12.3 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family TMEM37 PF15108.6 CBY11828.1 - 0.022 14.7 0.9 0.061 13.2 0.9 1.9 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF4999 PF16390.5 CBY11828.1 - 0.051 13.8 1.3 0.093 13.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function Phospholip_A2_1 PF00068.19 CBY11829.1 - 6.1e-17 62.1 5.8 1.3e-16 61.0 5.8 1.6 1 0 0 1 1 1 1 Phospholipase A2 LRR_8 PF13855.6 CBY11832.1 - 2.5e-27 94.4 35.3 3.5e-09 36.3 4.0 4.6 2 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY11832.1 - 3.7e-22 78.0 35.9 1.6e-05 25.1 5.4 5.8 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY11832.1 - 0.00024 20.6 15.4 0.026 14.0 3.0 3.4 1 1 3 4 4 4 4 Leucine-rich repeat EphA2_TM PF14575.6 CBY11832.1 - 0.0043 17.9 0.0 0.0083 17.0 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CBY11832.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 CBY11832.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LRR_1 PF00560.33 CBY11832.1 - 1 10.2 30.1 2.2 9.2 1.2 9.2 9 1 0 9 9 9 0 Leucine Rich Repeat DUF3050 PF11251.8 CBY11833.1 - 1.6e-89 299.5 0.1 2e-89 299.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Haem_oxygenas_2 PF14518.6 CBY11833.1 - 1.9e-05 24.5 0.0 6.3e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Iron-containing redox enzyme Myosin_head PF00063.21 CBY11834.1 - 1.5e-154 515.8 0.0 1.5e-154 515.8 0.0 2.5 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY11834.1 - 7.9e-130 434.6 255.9 9.2e-113 378.1 212.5 2.0 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.21 CBY11835.1 - 9.3e-84 281.9 0.1 1.1e-83 281.6 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 CBY11835.1 - 0.0037 17.5 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBY11835.1 - 0.069 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CBY11835.1 - 0.077 12.8 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 CBY11835.1 - 0.081 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 CBY11835.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CBY11835.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 CBY11835.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE C1q PF00386.21 CBY11836.1 - 3.2e-12 46.7 0.3 5.7e-12 46.0 0.3 1.4 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 CBY11836.1 - 0.043 13.6 3.4 0.076 12.8 3.4 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) LRR_8 PF13855.6 CBY11837.1 - 0.00042 20.0 0.5 0.00088 19.0 0.5 1.6 1 0 0 1 1 1 1 Leucine rich repeat NPR3 PF03666.13 CBY11837.1 - 0.095 11.5 1.0 0.12 11.2 1.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 CBY11837.1 - 0.18 10.6 2.1 0.18 10.6 2.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain LRR_4 PF12799.7 CBY11837.1 - 0.3 11.6 6.5 8.4 7.0 4.2 2.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) FSA_C PF10479.9 CBY11837.1 - 0.46 8.6 23.7 0.6 8.2 23.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Macoilin PF09726.9 CBY11837.1 - 0.48 8.9 2.1 0.51 8.8 2.1 1.1 1 0 0 1 1 1 0 Macoilin family AflR PF08493.10 CBY11837.1 - 1.7 8.0 22.6 2.4 7.5 22.6 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Pneumo_att_G PF05539.11 CBY11837.1 - 9.1 5.8 35.2 11 5.4 35.2 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Homeobox_KN PF05920.11 CBY11839.1 - 5.4e-15 55.0 0.3 5.4e-15 55.0 0.3 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CBY11839.1 - 1.8e-07 30.9 1.8 3.1e-07 30.1 1.8 1.4 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 CBY11839.1 - 0.046 14.3 0.5 0.083 13.5 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Lectin_C PF00059.21 CBY11840.1 - 3.9e-07 30.8 0.1 5.5e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Peptidase_M14 PF00246.24 CBY11841.1 - 2.4e-76 257.3 0.1 3.3e-76 256.9 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CBY11841.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family zf-C2H2 PF00096.26 CBY11842.1 - 1.4e-07 31.6 18.1 0.00049 20.4 6.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY11842.1 - 1.1e-06 28.8 15.8 0.00032 21.0 5.3 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY11842.1 - 7.1e-06 26.4 16.0 0.0015 19.2 5.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CBY11842.1 - 0.00016 22.0 8.3 0.096 13.1 1.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY11842.1 - 0.0017 18.3 10.4 0.029 14.4 3.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBY11842.1 - 0.0072 16.6 6.1 0.017 15.4 1.9 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 CBY11842.1 - 0.022 14.9 4.4 0.055 13.6 4.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-DNL PF05180.12 CBY11842.1 - 0.027 14.4 3.3 0.074 13.0 3.3 1.7 1 0 0 1 1 1 0 DNL zinc finger zf-CHCC PF10276.9 CBY11842.1 - 0.12 12.4 2.6 1.4 9.0 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 CBY11842.1 - 0.13 12.6 7.3 0.23 11.8 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CBY11842.1 - 0.26 12.0 3.0 13 6.5 0.3 2.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 CBY11842.1 - 0.32 11.1 2.9 2.7 8.1 0.4 2.4 1 1 1 2 2 2 0 CpXC protein DUF629 PF04780.12 CBY11842.1 - 0.62 8.5 6.0 1.9 6.9 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF629) TFIIS_C PF01096.18 CBY11842.1 - 0.9 9.4 4.5 4.6 7.2 0.3 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2256 PF10013.9 CBY11842.1 - 0.97 9.6 5.3 1.7 8.8 1.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_4 PF13717.6 CBY11842.1 - 1.5 8.8 4.5 2.7 8.0 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-AN1 PF01428.16 CBY11842.1 - 2.1 8.6 9.1 9.7 6.5 2.7 2.5 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 CBY11842.1 - 2.8 7.9 9.6 12 6.0 1.8 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type EGF_CA PF07645.15 CBY11843.1 - 1.7e-32 111.3 81.0 1.9e-07 31.2 8.1 5.9 5 0 0 5 5 5 5 Calcium-binding EGF domain cEGF PF12662.7 CBY11843.1 - 3.2e-13 49.3 42.6 0.00034 20.5 0.8 5.8 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY11843.1 - 9.6e-11 41.7 66.8 0.00019 21.6 6.1 7.2 5 3 2 7 7 7 5 EGF domain hEGF PF12661.7 CBY11843.1 - 1.8e-07 31.5 62.3 0.022 15.4 3.2 7.2 7 0 0 7 7 7 5 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY11843.1 - 3.8e-07 30.3 67.2 0.023 15.0 7.3 6.6 3 2 3 6 6 6 5 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY11843.1 - 0.00011 22.4 67.5 0.00085 19.6 7.4 6.3 6 0 0 6 6 6 3 Pvs28 EGF domain EGF PF00008.27 CBY11843.1 - 0.00061 20.0 78.9 0.023 15.0 6.7 7.4 5 1 2 7 7 7 5 EGF-like domain EGF_MSP1_1 PF12946.7 CBY11843.1 - 0.025 14.6 58.9 0.018 15.1 4.7 5.7 5 0 0 5 5 5 0 MSP1 EGF domain 1 zf-CCHC PF00098.23 CBY11844.1 - 4.9e-12 45.3 26.3 0.00015 21.7 2.9 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 CBY11844.1 - 0.085 12.8 20.9 0.087 12.8 4.4 3.5 3 0 0 3 3 3 0 Zinc knuckle PH PF00169.29 CBY11847.1 - 0.0012 19.3 2.1 0.07 13.6 0.0 2.6 2 0 0 2 2 2 2 PH domain DIE2_ALG10 PF04922.12 CBY11848.1 - 2e-33 116.2 13.1 2.6e-33 115.9 13.1 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family DUF2070 PF09843.9 CBY11848.1 - 1.8 6.8 8.8 1.9 6.7 8.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DIE2_ALG10 PF04922.12 CBY11849.1 - 2e-48 165.7 1.2 2.3e-48 165.5 1.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Lig_chan PF00060.26 CBY11849.1 - 0.38 10.6 4.6 0.098 12.5 0.6 1.9 1 1 1 2 2 2 0 Ligand-gated ion channel Phage_holin_3_7 PF05449.11 CBY11849.1 - 1 9.4 4.7 7.1 6.7 0.6 2.5 1 1 1 2 2 2 0 Putative 3TM holin, Phage_holin_3 RNA_pol_Rpb6 PF01192.22 CBY11850.1 - 4e-15 55.5 0.2 7.1e-15 54.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Glutaredoxin PF00462.24 CBY11851.1 - 7.7e-19 67.7 0.0 1e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 CBY11851.1 - 0.00054 20.3 0.0 0.00067 20.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY11851.1 - 0.004 17.4 0.0 0.005 17.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 CBY11851.1 - 0.0096 16.0 0.1 0.025 14.6 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 CBY11851.1 - 0.013 15.9 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CBY11851.1 - 0.03 14.8 0.2 0.054 13.9 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1887 PF09002.11 CBY11851.1 - 0.066 11.9 0.0 0.08 11.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Glutaredoxin PF00462.24 CBY11852.1 - 2.5e-16 59.7 0.1 3.7e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 CBY11852.1 - 0.0021 18.3 0.0 0.003 17.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 CBY11852.1 - 0.0047 17.4 0.0 0.0072 16.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY11852.1 - 0.044 14.0 0.0 0.074 13.2 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.6 CBY11852.1 - 0.054 13.9 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 CBY11852.1 - 0.11 12.2 0.1 0.19 11.5 0.1 1.5 1 1 0 1 1 1 0 DSBA-like thioredoxin domain RED_N PF07808.13 CBY11853.1 - 8.1e-60 202.3 11.1 8.1e-60 202.3 11.1 2.6 2 0 0 2 2 2 1 RED-like protein N-terminal region Det1 PF09737.9 CBY11853.1 - 1.2e-56 192.6 4.1 2e-56 191.8 4.1 1.3 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 RED_C PF07807.11 CBY11853.1 - 2.7e-42 143.8 9.5 2.7e-42 143.8 9.5 3.8 4 0 0 4 4 4 1 RED-like protein C-terminal region FXa_inhibition PF14670.6 CBY11854.1 - 0.045 14.1 10.7 0.16 12.2 10.7 2.1 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site CUB PF00431.20 CBY11855.1 - 6.4e-05 23.3 0.0 8.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 CUB domain DUF3819 PF12842.7 CBY11855.1 - 0.024 14.6 2.4 0.041 13.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) HSP20 PF00011.21 CBY11856.1 - 4e-14 52.6 0.0 5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBY11856.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA MHC2-interact PF09307.10 CBY11862.1 - 0.00016 21.6 0.0 0.00019 21.4 0.0 1.1 1 0 0 1 1 1 1 CLIP, MHC2 interacting TTRAP PF14203.6 CBY11862.1 - 0.012 15.6 0.8 0.033 14.1 0.8 1.7 1 1 0 1 1 1 0 Putative tranposon-transfer assisting protein DUF2213 PF09979.9 CBY11862.1 - 0.026 14.5 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) COX14 PF14880.6 CBY11862.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c assembly RVT_1 PF00078.27 CBY11863.1 - 1.6e-17 63.8 0.4 2.3e-17 63.3 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CBY11863.1 - 1.6e-06 28.1 0.3 2.2e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY11863.1 - 0.00069 19.9 0.1 0.0015 18.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Sulfotransfer_3 PF13469.6 CBY11864.1 - 8.7e-05 23.0 0.0 0.042 14.2 0.3 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY11864.1 - 0.00088 18.8 9.2 0.05 13.1 9.2 2.1 1 1 0 1 1 1 1 Sulfotransferase domain PrgH PF09480.10 CBY11864.1 - 0.013 14.8 0.9 0.55 9.5 0.0 2.9 3 0 0 3 3 3 0 Type III secretion system protein PrgH-EprH (PrgH) DUF2200 PF09966.9 CBY11864.1 - 0.033 14.3 0.5 0.21 11.7 0.0 2.5 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF4951 PF16309.5 CBY11864.1 - 0.13 12.3 0.8 0.33 11.0 0.2 2.1 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) Myelin_PLP PF01275.19 CBY11865.1 - 6.1e-05 23.0 4.7 0.0007 19.5 4.5 1.9 2 0 0 2 2 2 1 Myelin proteolipid protein (PLP or lipophilin) Myelin_PLP PF01275.19 CBY11866.1 - 3.3e-08 33.7 0.0 5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Peptidase_S28 PF05577.12 CBY11867.1 - 1.9e-74 251.0 0.1 2.3e-74 250.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 CBY11867.1 - 1.8e-06 27.4 0.0 4.7e-06 26.0 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY11867.1 - 1.5e-05 24.8 0.6 0.00011 21.9 0.0 2.6 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY11867.1 - 0.00019 21.0 0.3 0.00046 19.7 0.3 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 CBY11867.1 - 0.00042 19.1 0.1 0.00064 18.5 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 DUF2920 PF11144.8 CBY11867.1 - 0.023 13.9 0.2 0.045 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) BRO1 PF03097.18 CBY11868.1 - 8e-28 97.3 3.6 1e-27 97.0 3.6 1.1 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 CBY11868.1 - 0.031 14.4 0.7 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Hr1 repeat Lipoprotein_10 PF03202.13 CBY11868.1 - 0.04 14.4 0.4 0.04 14.4 0.4 1.7 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region DUF167 PF02594.16 CBY11868.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 DUF4901 PF16244.5 CBY11869.1 - 0.13 11.6 0.6 0.16 11.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) PET117 PF15786.5 CBY11869.1 - 0.18 12.1 2.3 0.14 12.5 0.8 1.7 1 1 1 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial MBG PF17883.1 CBY11870.1 - 0.0049 17.4 0.1 0.0049 17.4 0.1 3.2 2 1 0 3 3 3 1 MBG domain Skp1 PF01466.19 CBY11870.1 - 0.053 13.6 1.3 0.19 11.9 1.3 1.9 1 0 0 1 1 1 0 Skp1 family, dimerisation domain GlcNAc_2-epim PF07221.11 CBY11870.1 - 0.29 10.3 2.1 0.19 10.9 0.3 1.6 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) rRNA_processing PF08524.11 CBY11870.1 - 6.1 6.9 23.4 9.8 6.2 4.6 2.9 2 0 0 2 2 2 0 rRNA processing LPMO_10 PF03067.15 CBY11871.1 - 5.8e-34 118.5 0.3 7.2e-34 118.1 0.3 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY11871.1 - 4.1e-10 39.7 1.5 4.1e-10 39.7 1.5 2.1 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Baculo_PEP_C PF04513.12 CBY11872.1 - 0.75 9.8 6.3 1.1 9.3 5.4 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.8 CBY11872.1 - 9.9 6.5 13.3 0.43 10.9 3.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Cupin_8 PF13621.6 CBY11873.1 - 1.1e-31 110.5 0.0 1.5e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY11873.1 - 5.3e-06 26.1 0.0 2.6e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 CBY11873.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Cupin JmjC PF02373.22 CBY11873.1 - 0.078 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase PS_Dcarbxylase PF02666.15 CBY11874.1 - 4.3e-65 219.0 0.0 5e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.22 CBY11874.1 - 0.015 15.5 0.0 4.7 7.5 0.0 3.0 2 1 1 3 3 3 0 Peptidase family M23 PTS_EIIA_1 PF00358.20 CBY11874.1 - 0.13 12.0 0.0 29 4.4 0.0 2.9 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF515 PF04415.12 CBY11875.1 - 0.54 8.6 2.7 0.87 7.9 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) HK97-gp10_like PF04883.12 CBY11876.1 - 0.16 13.0 1.0 0.83 10.7 0.7 2.3 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component CBFD_NFYB_HMF PF00808.23 CBY11876.1 - 0.33 11.3 2.0 2.3 8.6 0.6 3.0 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ndc1_Nup PF09531.10 CBY11877.1 - 2.2 6.9 6.5 3.2 6.3 6.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAP_assoc PF03828.19 CBY11878.1 - 6.5e-12 45.5 0.3 1.3e-11 44.5 0.3 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY11878.1 - 6.6e-05 23.1 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain zf-CCHC PF00098.23 CBY11878.1 - 0.27 11.4 2.7 0.71 10.1 2.7 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 CBY11878.1 - 0.96 9.3 7.2 2.8 7.9 7.2 1.8 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 CBY11880.1 - 7.7e-10 38.6 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11880.1 - 2.4e-07 30.3 0.0 4.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase T4_deiodinase PF00837.17 CBY11881.1 - 2.7e-29 102.1 0.0 3.1e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase EGF_CA PF07645.15 CBY11884.1 - 1.1e-14 54.3 53.3 2.7e-08 33.9 4.3 5.5 3 1 2 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.7 CBY11884.1 - 1.5e-12 47.1 20.4 2.1e-05 24.3 0.3 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY11884.1 - 8.9e-09 35.5 63.7 3.9e-07 30.2 4.6 5.5 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY11884.1 - 0.0051 17.1 2.4 0.0051 17.1 2.4 6.5 4 2 0 5 5 5 2 EGF-like domain EGF_3 PF12947.7 CBY11884.1 - 0.033 14.4 1.5 0.033 14.4 1.5 5.8 5 2 0 5 5 5 0 EGF domain RANK_CRD_2 PF18278.1 CBY11884.1 - 0.042 14.0 0.9 0.042 14.0 0.9 3.8 4 0 0 4 4 4 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 ATG11 PF10377.9 CBY11886.1 - 1.6e-05 25.0 0.9 8.8e-05 22.6 0.0 2.5 2 1 0 2 2 2 1 Autophagy-related protein 11 DUF1664 PF07889.12 CBY11886.1 - 1 9.4 4.0 2.7 8.1 3.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PRK PF00485.18 CBY11888.1 - 2.6e-46 157.8 0.0 3.1e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 CBY11888.1 - 1.6e-05 24.7 0.3 0.018 14.7 0.0 2.2 2 0 0 2 2 2 2 Dephospho-CoA kinase Zeta_toxin PF06414.12 CBY11888.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 CBY11888.1 - 0.00081 19.8 2.7 0.0078 16.6 2.7 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY11888.1 - 0.00098 19.7 0.4 0.0039 17.7 0.4 1.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CBY11888.1 - 0.0093 15.7 0.2 3.1 7.5 0.0 2.1 2 0 0 2 2 2 2 Cytidylate kinase MMR_HSR1 PF01926.23 CBY11888.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 CBY11888.1 - 0.11 11.5 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 CBY11888.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PAN_1 PF00024.26 CBY11889.1 - 0.00019 21.3 1.4 0.00031 20.6 1.4 1.5 1 1 0 1 1 1 1 PAN domain PAN_4 PF14295.6 CBY11889.1 - 0.029 14.3 2.0 0.057 13.3 2.0 1.5 1 0 0 1 1 1 0 PAN domain DUF1235 PF06822.12 CBY11890.1 - 0.2 10.9 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) Myb_DNA-binding PF00249.31 CBY11891.1 - 1.7e-44 149.8 28.6 5.8e-13 48.8 0.9 6.1 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY11891.1 - 5.8e-40 135.4 15.2 5.9e-15 55.3 0.0 6.3 4 2 1 5 5 5 5 Myb-like DNA-binding domain Rap1_C PF11626.8 CBY11891.1 - 1.6e-05 24.9 5.2 2.4 8.3 0.1 5.3 2 2 2 4 4 4 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 CBY11891.1 - 3.8e-05 23.8 1.2 0.94 9.7 0.1 3.8 2 1 2 4 4 4 2 Rap1 Myb domain SLIDE PF09111.10 CBY11891.1 - 0.0015 18.6 1.7 1.3 9.1 0.1 4.0 2 2 1 4 4 4 2 SLIDE Myb_DNA-bind_4 PF13837.6 CBY11891.1 - 0.012 16.0 0.2 0.012 16.0 0.2 5.9 5 2 0 5 5 5 0 Myb/SANT-like DNA-binding domain DivIC PF04977.15 CBY11892.1 - 6.6 6.6 8.4 21 4.9 8.4 1.9 1 0 0 1 1 1 0 Septum formation initiator CAMSAP_CKK PF08683.11 CBY11893.1 - 2.3e-39 134.2 0.0 3.7e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated Zona_pellucida PF00100.23 CBY11894.1 - 4.3e-07 30.0 2.6 5e-07 29.8 2.6 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain zf-C2H2 PF00096.26 CBY11895.1 - 1.2e-11 44.4 24.9 0.00026 21.3 1.5 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY11895.1 - 2.5e-07 30.8 28.3 0.00011 22.5 4.0 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY11895.1 - 3.4e-06 27.4 21.2 0.012 16.4 1.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBY11895.1 - 0.00055 19.5 1.1 0.18 11.5 0.0 2.8 2 0 0 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain Actin_micro PF17003.5 CBY11895.1 - 0.0031 16.7 3.9 0.0073 15.5 0.1 2.1 1 1 1 2 2 2 1 Putative actin-like family zf-H2C2_5 PF13909.6 CBY11895.1 - 0.0077 16.0 7.2 0.0077 16.0 7.2 3.7 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 CBY11895.1 - 0.016 15.5 10.2 0.4 11.0 3.8 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CBY11895.1 - 0.042 14.3 7.4 2.6 8.6 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CBY11895.1 - 0.072 13.7 7.8 0.22 12.2 0.2 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CBY11895.1 - 0.094 13.0 8.5 0.037 14.3 5.6 1.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 CBY11895.1 - 0.58 10.8 9.3 6.6 7.4 0.7 3.1 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 CBY11895.1 - 0.95 9.6 6.5 0.41 10.8 3.1 2.2 2 1 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 CBY11895.1 - 3.9 7.5 10.1 2.8 7.9 1.0 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain OrsD PF12013.8 CBY11895.1 - 7.2 7.1 12.6 0.74 10.3 1.1 3.0 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D LRR_4 PF12799.7 CBY11896.1 - 7.3e-19 67.6 41.8 2e-07 31.2 0.1 5.8 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY11896.1 - 4.5e-11 42.6 12.2 8.6e-09 35.1 0.7 3.3 1 1 3 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 CBY11896.1 - 0.00013 21.6 35.1 0.012 15.4 4.8 4.9 3 1 2 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 CBY11896.1 - 1.9 8.7 17.4 10 6.4 0.3 6.4 6 1 0 6 6 6 0 Leucine Rich repeat LRR_3 PF07725.12 CBY11896.1 - 3.9 7.5 7.4 33 4.5 0.1 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat KH_1 PF00013.29 CBY11897.1 - 2.8e-08 33.5 0.0 6.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 KH domain TUDOR PF00567.24 CBY11897.1 - 4.4e-07 30.0 0.5 3.4e-05 23.8 0.0 3.3 4 0 0 4 4 4 1 Tudor domain KH_2 PF07650.17 CBY11897.1 - 0.012 15.4 0.1 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 KH domain KH_4 PF13083.6 CBY11897.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 KH domain Spectrin PF00435.21 CBY11898.1 - 2.5e-146 477.9 248.2 6.7e-17 61.9 5.6 21.3 19 2 2 21 21 21 21 Spectrin repeat SH3_1 PF00018.28 CBY11898.1 - 3.3e-07 29.8 0.0 1.1e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY11898.1 - 2.4e-06 27.1 0.0 7.5e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_6 PF13405.6 CBY11898.1 - 1.8e-05 24.3 0.4 0.00023 20.8 0.2 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY11898.1 - 2e-05 23.8 1.1 0.00011 21.5 0.3 2.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBY11898.1 - 0.00013 22.3 2.1 0.00013 22.3 2.1 5.1 5 0 0 5 5 5 1 EF-hand domain pair SH3_9 PF14604.6 CBY11898.1 - 0.00016 21.4 0.0 0.00065 19.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain EFhand_Ca_insen PF08726.10 CBY11898.1 - 0.00023 21.2 1.0 0.0013 18.8 0.0 3.0 3 0 0 3 3 3 1 Ca2+ insensitive EF hand PKcGMP_CC PF16808.5 CBY11899.1 - 0.03 14.2 2.0 0.03 14.2 2.0 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HSBP1 PF06825.12 CBY11901.1 - 0.024 14.5 0.2 0.057 13.3 0.2 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SF-assemblin PF06705.11 CBY11901.1 - 0.039 13.3 1.0 0.062 12.6 1.0 1.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin ABC_tran PF00005.27 CBY11903.1 - 8.8e-49 165.5 0.1 6.1e-24 85.1 0.1 2.7 3 0 0 3 3 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CBY11903.1 - 3.5e-35 121.7 40.2 1.5e-23 83.5 16.3 4.1 2 2 2 4 4 4 3 ABC-2 family transporter protein AAA_21 PF13304.6 CBY11903.1 - 1.1e-18 68.1 1.3 3.9e-05 23.6 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBY11903.1 - 2.6e-08 34.6 0.9 0.0002 21.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CBY11903.1 - 2.5e-05 23.9 0.7 0.0049 16.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBY11903.1 - 2.7e-05 24.1 0.4 0.0049 16.8 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 CBY11903.1 - 2.9e-05 23.9 0.0 0.011 15.4 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 CBY11903.1 - 7.7e-05 22.7 0.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain SMC_N PF02463.19 CBY11903.1 - 0.00011 21.8 1.2 0.26 10.7 0.0 3.9 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 CBY11903.1 - 0.0011 18.6 0.2 0.097 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBY11903.1 - 0.0013 18.5 0.3 0.88 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CBY11903.1 - 0.0034 17.7 0.2 1.2 9.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF4162 PF13732.6 CBY11903.1 - 0.006 17.3 0.1 0.006 17.3 0.1 2.4 3 0 0 3 3 1 1 Domain of unknown function (DUF4162) MMR_HSR1 PF01926.23 CBY11903.1 - 0.015 15.3 0.2 3.2 7.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 CBY11903.1 - 0.019 15.4 0.2 13 6.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY11903.1 - 0.02 15.3 0.0 1.3 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 CBY11903.1 - 0.039 13.7 0.4 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CBY11903.1 - 0.18 11.4 1.9 3.1 7.4 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 CBY11903.1 - 0.26 11.1 1.6 0.49 10.2 0.2 2.1 2 0 0 2 2 2 0 MukB N-terminal XPG_I_2 PF12813.7 CBY11904.1 - 4.3e-06 26.4 0.0 7.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Glyco_transf_7N PF13733.6 CBY11905.1 - 2.7e-31 108.0 0.3 3.9e-31 107.5 0.3 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY11905.1 - 5.2e-27 93.3 0.8 8.8e-27 92.6 0.8 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Pkinase PF00069.25 CBY11906.1 - 9e-65 218.7 0.0 1.3e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY11906.1 - 2.3e-35 122.1 0.0 3.4e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 CBY11906.1 - 2.2e-28 98.6 0.2 4.3e-28 97.6 0.2 1.5 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 CBY11906.1 - 3.6e-27 94.0 22.4 7.9e-14 51.3 4.8 3.2 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CBY11906.1 - 1.4e-05 25.7 0.6 4.4e-05 24.1 0.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CBY11906.1 - 2.7e-05 23.3 0.5 4.9e-05 22.4 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain C1_2 PF03107.16 CBY11906.1 - 0.0032 17.7 2.8 0.0032 17.7 2.8 3.1 3 0 0 3 3 3 1 C1 domain DOCK-C2 PF14429.6 CBY11906.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins PHD_2 PF13831.6 CBY11906.1 - 0.021 14.3 0.8 0.021 14.3 0.8 3.5 4 0 0 4 4 3 0 PHD-finger APH PF01636.23 CBY11906.1 - 0.022 14.7 0.1 0.066 13.1 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY11906.1 - 0.035 13.4 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RNA_POL_M_15KD PF02150.16 CBY11906.1 - 0.043 13.7 0.7 0.043 13.7 0.7 3.1 3 0 0 3 3 2 0 RNA polymerases M/15 Kd subunit Kdo PF06293.14 CBY11906.1 - 0.097 12.0 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YccV-like PF08755.11 CBY11906.1 - 0.16 12.5 0.3 0.83 10.2 0.1 2.3 2 0 0 2 2 2 0 Hemimethylated DNA-binding protein YccV like eIF-4B PF06273.11 CBY11906.1 - 0.71 8.9 6.0 1.1 8.2 6.0 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DZR PF12773.7 CBY11906.1 - 1.4 9.0 13.3 2 8.5 3.2 3.3 3 0 0 3 3 3 0 Double zinc ribbon zf-RING-like PF08746.11 CBY11906.1 - 2.3 8.6 18.0 6 7.3 3.2 2.9 2 0 0 2 2 2 0 RING-like domain zf-RING_9 PF13901.6 CBY11906.1 - 3.2 7.7 18.6 0.36 10.8 3.1 2.8 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon DUF2318 PF10080.9 CBY11906.1 - 4.9 7.3 11.7 0.11 12.6 1.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) Cob_adeno_trans PF01923.18 CBY11907.1 - 4.2e-55 186.3 0.1 4.9e-55 186.1 0.1 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DXP_synthase_N PF13292.6 CBY11907.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase BRO1 PF03097.18 CBY11908.1 - 8.5e-78 261.8 0.0 1.4e-77 261.2 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 CBY11908.1 - 6e-10 39.1 0.0 1.6e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.24 CBY11908.1 - 1.2e-09 38.4 1.3 1.8e-09 37.8 0.2 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CBY11908.1 - 1.6e-07 31.1 0.2 1.6e-07 31.1 0.2 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CBY11908.1 - 5.9e-06 26.5 0.1 1.5e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain DUF5050 PF16472.5 CBY11909.1 - 0.22 10.7 1.0 0.56 9.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) HSA PF07529.13 CBY11911.1 - 1.3e-13 51.1 3.5 1.3e-13 51.1 3.5 2.7 2 1 1 3 3 3 1 HSA Helicase_C PF00271.31 CBY11911.1 - 0.0035 17.7 0.2 0.039 14.3 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CBY11911.1 - 0.0039 16.4 0.5 0.0039 16.4 0.5 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 VPS9 PF02204.18 CBY11912.1 - 4.7e-20 71.8 0.0 3.4e-19 69.0 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain MerR-DNA-bind PF09278.11 CBY11912.1 - 5.8 7.5 7.9 1.5 9.4 0.2 3.3 3 0 0 3 3 3 0 MerR, DNA binding RasGAP PF00616.19 CBY11913.1 - 2.3e-13 50.4 0.0 5.5e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF1495 PF07381.11 CBY11914.1 - 0.078 12.8 0.2 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) OrsD PF12013.8 CBY11914.1 - 0.1 13.1 1.1 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D KASH_CCD PF14662.6 CBY11914.1 - 0.14 12.0 23.5 1.1 9.1 2.0 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 CBY11914.1 - 0.25 11.4 21.2 0.052 13.6 3.7 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cnn_1N PF07989.11 CBY11914.1 - 1.7 8.9 18.7 4.4 7.5 4.8 4.2 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 THOC7 PF05615.13 CBY11914.1 - 4.4 7.6 23.7 0.028 14.7 7.0 2.9 1 1 2 3 3 3 0 Tho complex subunit 7 LsmAD PF06741.13 CBY11914.1 - 8.9 6.9 12.0 13 6.4 5.4 3.5 1 1 1 2 2 2 0 LsmAD domain DUF4545 PF15078.6 CBY11916.1 - 0.0037 16.3 0.1 0.0042 16.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4545) KCNQ_channel PF03520.14 CBY11917.1 - 1.3e-36 126.2 0.4 1.7e-36 125.8 0.4 1.1 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel MMR_HSR1_C PF08438.10 CBY11917.1 - 0.083 13.5 0.3 9 6.9 0.0 2.2 1 1 0 2 2 2 0 GTPase of unknown function C-terminal Allexi_40kDa PF05549.11 CBY11917.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Ion_trans PF00520.31 CBY11918.1 - 1.5e-28 99.7 12.4 2e-28 99.3 12.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY11918.1 - 1.9e-11 43.8 10.7 1.9e-11 43.8 10.7 2.7 2 1 1 3 3 3 1 Ion channel IQ PF00612.27 CBY11918.1 - 0.079 12.8 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Lig_chan PF00060.26 CBY11918.1 - 1.4 8.7 7.2 0.27 11.1 0.7 2.4 2 1 0 2 2 2 0 Ligand-gated ion channel DUF1600 PF07667.11 CBY11918.1 - 2.3 8.5 7.9 0.47 10.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1600) OAD_gamma PF04277.13 CBY11918.1 - 5.5 7.6 5.4 12 6.6 0.1 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain VWA PF00092.28 CBY11919.1 - 0.013 15.8 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 CBY11919.1 - 0.014 16.0 0.0 0.021 15.5 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Trypsin PF00089.26 CBY11920.1 - 7.7e-14 52.0 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin C2 PF00168.30 CBY11922.1 - 5.3e-10 39.5 0.0 7.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 C2 domain Atg14 PF10186.9 CBY11924.1 - 0.92 8.5 15.7 2.1 7.4 15.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 CBY11924.1 - 4.5 7.3 18.1 0.5 10.4 3.6 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 CBY11924.1 - 5.8 7.3 18.0 3.3 8.1 10.3 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Piwi PF02171.17 CBY11926.1 - 1.4e-34 119.7 0.0 1.7e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Piwi domain eIF3_subunit PF08597.10 CBY11926.1 - 0.1 12.5 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ArgoN PF16486.5 CBY11927.1 - 0.0021 18.7 0.0 0.0045 17.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CBY11927.1 - 0.012 15.2 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Argonaute linker 1 domain HipN PF18253.1 CBY11927.1 - 0.22 11.2 0.5 0.56 9.9 0.1 1.8 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain DUF5320 PF17253.2 CBY11927.1 - 0.48 11.5 4.7 5 8.3 4.7 2.4 1 1 0 1 1 1 0 Family of unknown function (DUF5320) Vfa1 PF08432.10 CBY11927.1 - 0.75 10.1 3.7 1.3 9.4 3.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Piwi PF02171.17 CBY11928.1 - 1.8e-63 214.6 0.0 2.2e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 CBY11928.1 - 1.4e-05 25.2 0.3 5e-05 23.5 0.3 1.9 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 CBY11928.1 - 0.0013 19.0 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain RhoGAP PF00620.27 CBY11929.1 - 1.7e-29 102.6 0.1 5.9e-29 100.9 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain C1_2 PF03107.16 CBY11929.1 - 2e-06 28.0 3.0 4.8e-06 26.8 3.0 1.7 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 CBY11929.1 - 2.1e-05 24.3 11.0 3.8e-05 23.5 11.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CBY11929.1 - 0.34 10.9 7.6 0.74 9.8 7.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Tox-URI2 PF15653.6 CBY11929.1 - 0.38 11.1 3.5 0.43 10.9 0.4 2.7 2 1 1 3 3 3 0 URI fold toxin 2 Zf_RING PF16744.5 CBY11929.1 - 0.8 9.9 6.9 2.9 8.1 6.9 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger DZR PF12773.7 CBY11929.1 - 0.81 9.8 7.8 1.7 8.7 7.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon PHD PF00628.29 CBY11929.1 - 1.3 9.0 8.2 2.6 8.0 8.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 CBY11929.1 - 2.2 8.4 8.2 5.7 7.1 8.2 1.7 1 0 0 1 1 1 0 Zinc-finger DivIC PF04977.15 CBY11929.1 - 4.8 7.0 9.7 0.65 9.8 0.5 3.2 3 0 0 3 3 3 0 Septum formation initiator NDUF_B7 PF05676.13 CBY11931.1 - 4.1 7.2 12.1 4.1 7.2 2.2 3.0 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Homeodomain PF00046.29 CBY11932.1 - 4.7e-19 68.0 7.9 9.4e-19 67.0 7.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY11932.1 - 0.00037 20.3 0.8 0.00098 19.0 0.8 1.7 1 0 0 1 1 1 1 Homeobox KN domain RRM_1 PF00076.22 CBY11933.1 - 7.7e-21 73.7 0.9 6.2e-14 51.6 0.0 2.5 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY11933.1 - 0.0089 16.1 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CBY11933.1 - 0.11 12.7 0.1 0.65 10.2 0.1 2.0 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter EGF_CA PF07645.15 CBY11934.1 - 1.4e-73 242.8 194.3 1.3e-11 44.4 4.3 12.9 12 1 1 13 13 13 11 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY11934.1 - 4.7e-45 151.6 169.6 1.3e-09 38.2 8.0 12.3 10 2 2 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY11934.1 - 7.9e-37 124.8 112.6 8.1e-10 38.5 2.7 12.3 12 0 0 12 12 12 9 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY11934.1 - 4.9e-27 93.8 161.6 7.6e-05 22.8 5.2 13.5 12 2 1 13 13 13 11 EGF domain EGF PF00008.27 CBY11934.1 - 2.4e-12 46.9 155.9 0.00048 20.4 5.2 13.3 12 1 0 12 12 12 10 EGF-like domain hEGF PF12661.7 CBY11934.1 - 2.7e-06 27.8 145.0 0.047 14.3 2.7 14.9 14 2 0 14 14 14 9 Human growth factor-like EGF Laminin_G_2 PF02210.24 CBY11934.1 - 3.6e-05 24.3 0.0 0.0001 22.8 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.23 CBY11934.1 - 0.023 14.9 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain EF-hand_7 PF13499.6 CBY11935.1 - 2.2e-25 88.9 7.5 2.9e-12 46.9 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY11935.1 - 9.9e-25 84.2 15.7 1.1e-07 30.8 2.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY11935.1 - 3.7e-22 76.3 11.1 4.3e-06 26.2 0.3 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CBY11935.1 - 2.7e-15 55.9 14.9 8.6e-09 35.1 2.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CBY11935.1 - 3.1e-12 45.4 15.2 0.0048 16.3 1.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBY11935.1 - 1.5e-07 31.6 0.7 1.1e-05 25.7 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CBY11935.1 - 1.4e-06 28.2 6.5 0.00087 19.2 0.8 2.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY11935.1 - 3.2e-06 27.4 0.2 0.00083 19.7 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 CBY11935.1 - 0.0033 17.5 0.1 0.49 10.5 0.1 2.6 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF3741 PF12552.8 CBY11935.1 - 0.028 14.4 0.9 1.3 9.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) EF-hand_14 PF17959.1 CBY11935.1 - 0.036 14.4 0.7 4.7 7.6 0.2 3.0 2 1 1 3 3 3 0 EF-hand domain Reprolysin_2 PF13574.6 CBY11936.1 - 2.3e-29 102.7 0.1 8e-29 100.9 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CBY11936.1 - 3.1e-24 86.2 0.0 6.6e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY11936.1 - 2.1e-17 63.8 0.0 3.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CBY11936.1 - 6.3e-13 49.3 30.4 6.3e-13 49.3 30.4 3.2 2 1 0 2 2 2 1 Disintegrin Reprolysin_4 PF13583.6 CBY11936.1 - 3.9e-10 39.7 0.0 9.4e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 CBY11936.1 - 3.3e-05 24.1 0.1 7.8e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.9 CBY11936.1 - 0.081 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 UPF0370 PF13980.6 CBY11936.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) RIO1 PF01163.22 CBY11937.1 - 2.6e-68 229.4 0.0 2.6e-68 229.4 0.0 2.4 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CBY11937.1 - 0.0047 16.9 0.2 0.035 14.0 0.2 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4498 PF14926.6 CBY11938.1 - 4.7e-50 170.2 3.1 5.6e-50 170.0 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) GEP5 PF17053.5 CBY11938.1 - 0.04 13.8 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 SCO1-SenC PF02630.14 CBY11939.1 - 2.1e-41 141.0 0.0 3.2e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CBY11939.1 - 0.00051 19.9 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CBY11939.1 - 0.0077 16.5 0.0 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like DUF4361 PF14274.6 CBY11940.1 - 0.27 11.5 3.1 0.35 11.1 2.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) NTPase_1 PF03266.15 CBY11941.1 - 3.5e-36 124.6 0.3 4.5e-36 124.3 0.3 1.1 1 0 0 1 1 1 1 NTPase AAA PF00004.29 CBY11941.1 - 4.6e-06 27.1 0.9 1.4e-05 25.5 0.9 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY11941.1 - 0.00029 21.2 0.0 0.00033 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CBY11941.1 - 0.00038 21.0 0.4 0.0014 19.2 0.4 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CBY11941.1 - 0.00091 19.2 0.2 0.00091 19.2 0.2 1.9 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CBY11941.1 - 0.0017 18.7 0.4 0.2 12.1 0.0 2.7 2 1 1 3 3 3 1 RNA helicase AAA_30 PF13604.6 CBY11941.1 - 0.0017 18.1 0.5 0.0032 17.2 0.1 1.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBY11941.1 - 0.002 18.4 0.9 0.01 16.1 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 CBY11941.1 - 0.0031 17.1 0.0 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 CBY11941.1 - 0.0042 17.3 0.0 0.0074 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBY11941.1 - 0.0062 16.5 0.3 0.095 12.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SRP54 PF00448.22 CBY11941.1 - 0.0078 15.9 1.3 0.095 12.3 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain cobW PF02492.19 CBY11941.1 - 0.0083 15.7 2.1 0.029 14.0 0.0 2.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CBY11941.1 - 0.0083 15.9 2.8 0.066 12.9 2.8 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY11941.1 - 0.0084 16.5 1.0 0.06 13.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CBY11941.1 - 0.011 15.8 1.7 0.4 10.7 1.7 2.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CBY11941.1 - 0.013 15.5 0.7 0.061 13.4 0.7 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 CBY11941.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.10 CBY11941.1 - 0.026 14.0 0.1 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CBY11941.1 - 0.03 13.6 0.2 0.067 12.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 CBY11941.1 - 0.031 13.3 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 CBY11941.1 - 0.033 13.9 0.2 0.11 12.3 0.2 2.1 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CBY11941.1 - 0.037 13.8 0.5 0.35 10.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CBY11941.1 - 0.038 13.2 0.0 0.07 12.4 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain DUF2478 PF10649.9 CBY11941.1 - 0.043 13.4 0.0 0.078 12.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2478) ATP_bind_1 PF03029.17 CBY11941.1 - 0.048 13.4 1.4 0.47 10.2 0.0 2.2 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 CBY11941.1 - 0.063 13.7 3.3 0.19 12.1 0.6 2.2 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 CBY11941.1 - 0.092 11.9 0.6 0.15 11.3 0.1 1.6 2 1 0 1 1 1 0 NB-ARC domain MobB PF03205.14 CBY11941.1 - 0.13 12.2 0.9 0.72 9.8 0.0 2.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ZU5 PF00791.20 CBY11943.1 - 0.0072 16.7 0.0 0.0093 16.3 0.0 1.2 1 0 0 1 1 1 1 ZU5 domain LRR_8 PF13855.6 CBY11947.1 - 5.6e-27 93.3 37.6 1.1e-08 34.7 0.9 5.2 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 CBY11947.1 - 1.5e-09 38.0 43.3 0.0038 17.6 3.0 6.1 1 1 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY11947.1 - 0.00051 19.6 11.5 0.0015 18.0 3.2 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 CBY11947.1 - 0.00078 19.4 0.2 0.0021 18.0 0.1 1.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) PARP_reg PF02877.14 CBY11947.1 - 0.0016 18.5 0.1 0.0043 17.1 0.1 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain UDPGT PF00201.18 CBY11948.1 - 7.1e-143 477.0 1.0 8e-143 476.8 1.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CBY11948.1 - 1e-07 32.1 0.0 3.8e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain PDDEXK_1 PF12705.7 CBY11949.1 - 0.00049 20.1 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 PD-(D/E)XK nuclease superfamily EF-hand_7 PF13499.6 CBY11950.1 - 5.2e-16 58.8 1.5 2.2e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY11950.1 - 1.3e-13 49.7 1.4 0.0025 17.6 0.0 4.5 3 1 1 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CBY11950.1 - 5.2e-12 44.4 1.2 0.022 14.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBY11950.1 - 1.3e-09 38.3 0.1 4.1e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CBY11950.1 - 2.4e-09 36.9 0.4 4.4e-06 26.4 0.0 3.5 2 1 2 4 4 4 1 EF-hand domain pair EF-hand_11 PF08976.11 CBY11950.1 - 0.00077 20.3 0.3 0.0021 18.9 0.1 1.7 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 CBY11950.1 - 0.0013 17.3 0.1 0.0016 17.1 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Caleosin PF05042.13 CBY11950.1 - 0.0086 16.0 1.3 1.3 8.9 0.5 2.4 1 1 1 2 2 2 2 Caleosin related protein PHB_acc_N PF07879.11 CBY11950.1 - 0.014 15.4 0.4 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain EAL PF00563.20 CBY11950.1 - 0.059 12.9 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 EAL domain DUF1456 PF07308.13 CBY11950.1 - 0.082 13.3 0.3 4.1 7.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) EFhand_Ca_insen PF08726.10 CBY11950.1 - 0.087 12.9 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF99 PF01949.16 CBY11950.1 - 0.13 11.7 0.1 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF99 Lactamase_B PF00753.27 CBY11951.1 - 2.1e-13 50.7 5.1 1.1e-07 32.0 0.3 2.1 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY11951.1 - 0.02 14.4 2.1 0.05 13.1 2.1 1.8 1 1 1 2 2 2 0 Beta-lactamase superfamily domain EF-hand_6 PF13405.6 CBY11953.1 - 8.6e-07 28.4 0.2 1.4e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CBY11953.1 - 1.9e-06 27.0 0.3 2.6e-06 26.6 0.3 1.2 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CBY11953.1 - 0.0001 22.1 0.1 0.00011 22.0 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 CBY11953.1 - 0.0011 19.4 0.0 0.0018 18.7 0.0 1.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 CBY11953.1 - 0.0075 16.6 0.1 0.014 15.7 0.0 1.4 2 0 0 2 2 2 1 EF-hand domain Malate_DH PF12434.8 CBY11953.1 - 0.025 14.6 1.2 0.032 14.3 1.2 1.2 1 0 0 1 1 1 0 Malate dehydrogenase enzyme GCFC PF07842.12 CBY11955.1 - 2e-44 152.3 20.2 3.6e-44 151.4 20.2 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 CBY11955.1 - 2.2e-19 69.8 6.8 2.2e-19 69.8 6.8 3.8 2 2 2 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.23 CBY11955.1 - 2.9e-14 52.7 2.7 5.6e-14 51.8 2.7 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBY11955.1 - 7.2e-06 26.0 2.5 3.2e-05 23.9 2.5 2.2 1 0 0 1 1 1 1 G-patch domain Peptidase_C48 PF02902.19 CBY11956.1 - 2.6e-33 115.7 1.6 1.3e-32 113.4 0.2 2.0 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RIFIN PF02009.16 CBY11957.1 - 0.0025 17.8 0.1 0.0029 17.6 0.1 1.0 1 0 0 1 1 1 1 Rifin IRK_C PF17655.1 CBY11958.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain IRK_C PF17655.1 CBY11959.1 - 2.6e-41 141.1 0.1 4.2e-41 140.4 0.1 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY11959.1 - 6.1e-40 136.3 2.6 2.4e-39 134.4 1.4 2.1 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY11959.1 - 0.027 14.5 5.1 0.091 12.7 5.1 2.0 1 1 0 1 1 1 0 Ion channel GMC_oxred_C PF05199.13 CBY11960.1 - 4.2e-40 137.6 0.1 6.3e-40 137.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CBY11960.1 - 3.5e-17 62.7 0.1 6e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Kelch_2 PF07646.15 CBY11961.1 - 0.059 13.4 0.4 17 5.5 0.0 3.3 3 0 0 3 3 3 0 Kelch motif LRR_4 PF12799.7 CBY11962.1 - 4.7e-18 65.0 23.1 1.1e-05 25.7 0.6 6.1 3 3 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY11962.1 - 1.6e-13 50.2 24.3 1.5e-05 24.6 0.9 4.8 3 2 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CBY11962.1 - 1.6e-11 44.0 10.0 1.4e-06 27.9 0.0 4.2 2 2 1 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 CBY11962.1 - 1.4e-05 24.8 14.4 3 8.1 0.1 7.4 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 CBY11962.1 - 0.035 14.6 24.0 1.2 9.9 0.2 7.6 7 2 0 7 7 7 0 Leucine Rich Repeat gag_pre-integrs PF13976.6 CBY11962.1 - 0.081 12.8 0.5 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 GAG-pre-integrase domain DDE_Tnp_IS240 PF13610.6 CBY11962.1 - 0.086 13.1 0.2 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 DDE domain LRR_2 PF07723.13 CBY11962.1 - 1.7 9.4 10.5 53 4.7 0.2 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 CBY11963.1 - 1e-25 89.4 30.0 0.00014 22.2 0.1 8.1 6 1 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY11963.1 - 2.6e-19 68.7 23.9 6.2e-09 35.5 6.0 6.0 5 1 1 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 CBY11963.1 - 1.4e-15 57.2 14.8 4.1e-09 36.2 2.1 3.8 2 2 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CBY11963.1 - 6.8e-07 28.9 19.0 2 8.7 0.3 8.4 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 CBY11963.1 - 0.025 15.1 17.0 35 5.5 0.4 7.7 6 1 0 6 6 6 0 Leucine Rich Repeat Carbpep_Y_N PF05388.11 CBY11963.1 - 0.18 12.3 2.6 0.2 12.2 0.5 2.3 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide Pkinase_Tyr PF07714.17 CBY11964.1 - 9.9e-75 251.2 0.0 1.7e-74 250.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY11964.1 - 3.2e-35 121.8 0.0 7.7e-35 120.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain SieB PF14163.6 CBY11964.1 - 0.0015 18.0 0.1 0.0043 16.5 0.1 1.7 1 0 0 1 1 1 1 Super-infection exclusion protein B Pkinase_fungal PF17667.1 CBY11964.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ig_3 PF13927.6 CBY11964.1 - 0.022 15.3 0.0 0.051 14.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 CBY11964.1 - 0.03 14.6 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 CBY11964.1 - 0.18 12.0 0.6 0.6 10.3 0.0 2.1 2 1 0 2 2 2 0 Immunoglobulin V-set domain Sugar_tr PF00083.24 CBY11965.1 - 5e-79 266.3 14.4 1e-70 238.8 11.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBY11965.1 - 1.1e-28 100.1 15.5 2.4e-28 99.1 15.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CBY11965.1 - 0.0026 16.2 1.1 0.0026 16.2 1.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Defensin_beta_2 PF13841.6 CBY11965.1 - 0.075 13.5 0.5 0.16 12.5 0.5 1.6 1 0 0 1 1 1 0 Beta defensin MFS_2 PF13347.6 CBY11965.1 - 2.8 6.4 16.1 0.038 12.6 2.8 2.8 1 1 1 3 3 3 0 MFS/sugar transport protein Aldedh PF00171.22 CBY11966.1 - 1e-10 40.7 0.1 1.3e-10 40.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SIKE PF05769.11 CBY11967.1 - 3.2e-24 85.9 10.1 9e-24 84.4 10.1 1.8 1 0 0 1 1 1 1 SIKE family Tho2 PF11262.8 CBY11967.1 - 0.052 12.8 4.8 2.5 7.2 2.3 2.4 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 LIAS_N PF16881.5 CBY11967.1 - 0.12 12.8 3.4 0.19 12.2 0.2 2.6 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family BRE1 PF08647.11 CBY11967.1 - 2.4 8.3 12.5 0.72 10.0 2.2 2.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4661 PF15576.6 CBY11967.1 - 2.8 7.8 6.7 0.86 9.5 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) NYD-SP28_assoc PF14775.6 CBY11967.1 - 6 7.1 8.6 27 5.0 0.4 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain DEAD_assoc PF08494.11 CBY11968.1 - 0.029 14.2 0.3 0.037 13.8 0.3 1.3 1 0 0 1 1 1 0 DEAD/H associated ADIP PF11559.8 CBY11968.1 - 0.083 13.0 23.2 0.23 11.6 11.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.12 CBY11968.1 - 0.088 12.7 2.8 2.3 8.2 0.1 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Vps54_N PF10475.9 CBY11968.1 - 0.12 11.7 12.8 0.061 12.6 6.9 2.2 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Exonuc_VII_L PF02601.15 CBY11968.1 - 0.26 10.8 8.7 0.29 10.7 8.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YscO-like PF16789.5 CBY11968.1 - 0.62 10.1 22.5 0.069 13.2 10.7 2.2 1 1 1 2 2 2 0 YscO-like protein DUF724 PF05266.14 CBY11968.1 - 0.89 9.3 21.8 2.1 8.1 11.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 CBY11968.1 - 1.1 8.7 19.5 1.4 8.3 19.0 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 CBY11968.1 - 1.5 8.8 28.9 3.2 7.8 28.9 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Paralemmin PF03285.15 CBY11968.1 - 1.9 8.0 21.6 2.6 7.5 12.3 2.1 1 1 1 2 2 2 0 Paralemmin Fez1 PF06818.15 CBY11968.1 - 2 8.8 20.7 5.7 7.3 4.1 2.2 1 1 1 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 CBY11968.1 - 2.5 8.2 24.6 1.4 9.0 18.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 CBY11968.1 - 2.7 8.5 15.9 0.48 10.9 2.2 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF5339 PF17274.2 CBY11968.1 - 3.6 8.5 14.6 0.85 10.5 4.7 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5339) NPV_P10 PF05531.12 CBY11968.1 - 5.7 7.5 9.0 3 8.4 3.5 2.9 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 CBY11968.1 - 6.1 7.5 8.0 4.8 7.9 3.4 2.9 1 1 1 2 2 2 0 SlyX PRKG1_interact PF15898.5 CBY11968.1 - 9.1 7.2 25.3 2.1 9.3 15.2 2.9 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Phlebovirus_NSM PF07246.11 CBY11968.1 - 9.9 5.4 15.9 0.59 9.5 9.3 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M AKAP28 PF14469.6 CBY11969.1 - 4.3e-47 158.8 0.2 4.9e-47 158.7 0.2 1.0 1 0 0 1 1 1 1 28 kDa A-kinase anchor GST_C PF00043.25 CBY11970.1 - 0.0014 18.9 0.5 0.012 15.8 0.0 2.8 4 0 0 4 4 4 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBY11970.1 - 0.049 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBY11970.1 - 0.053 13.9 0.0 0.27 11.6 0.0 2.3 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain Mnd1 PF03962.15 CBY11970.1 - 0.062 13.6 0.5 0.24 11.7 0.2 2.1 2 0 0 2 2 2 0 Mnd1 HTH domain GST_N_4 PF17172.4 CBY11970.1 - 0.063 14.0 0.4 1.6 9.6 0.1 2.7 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain Arf PF00025.21 CBY11971.1 - 1.5e-43 148.3 0.0 1.8e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY11971.1 - 2.4e-12 47.1 0.0 3.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY11971.1 - 8.1e-12 45.0 0.0 9.5e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY11971.1 - 4.1e-11 42.6 0.4 2.8e-06 26.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY11971.1 - 5.7e-10 38.9 0.0 7.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY11971.1 - 1.5e-05 24.5 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY11971.1 - 4.6e-05 23.5 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY11971.1 - 0.016 15.5 0.0 0.07 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CBY11971.1 - 0.083 12.4 0.0 1.9 8.0 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain UCH PF00443.29 CBY11972.1 - 4.6e-50 170.5 0.0 6.4e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY11972.1 - 1.2e-14 54.7 0.3 8.7e-11 42.0 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CBY11972.1 - 0.00073 19.1 0.2 0.57 9.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Cauli_AT PF03233.13 CBY11972.1 - 0.11 12.4 0.2 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Aphid transmission protein OTU PF02338.19 CBY11973.1 - 1e-09 38.9 0.0 2.6e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Zn-ribbon_8 PF09723.10 CBY11973.1 - 0.093 12.9 3.2 4.4 7.5 0.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Mu-like_Com PF10122.9 CBY11973.1 - 0.12 11.8 1.9 7.8 6.0 0.2 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com Lar_restr_allev PF14354.6 CBY11973.1 - 4.3 7.8 4.8 16 5.9 0.5 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar BSD PF03909.17 CBY11974.1 - 2.9e-08 33.6 0.3 2.9e-08 33.6 0.3 2.5 2 0 0 2 2 2 1 BSD domain DUF1451 PF07295.11 CBY11974.1 - 0.0062 16.6 0.7 0.0062 16.6 0.7 2.5 2 0 0 2 2 2 1 Zinc-ribbon containing domain RRM_1 PF00076.22 CBY11975.1 - 2.4e-17 62.5 0.0 3.8e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4692 PF15763.5 CBY11976.1 - 3.3 8.1 11.3 3.6 8.0 10.7 1.5 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) CCDC106 PF15794.5 CBY11976.1 - 3.6 7.2 10.2 0.43 10.3 5.7 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 WD40 PF00400.32 CBY11977.1 - 2.6e-05 24.9 7.3 0.04 14.8 0.1 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY11977.1 - 0.00047 20.4 0.2 0.87 9.9 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY11977.1 - 0.00087 18.3 0.2 0.051 12.5 0.0 3.1 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein p25-alpha PF05517.12 CBY11977.1 - 2.3 8.3 5.7 4.9 7.3 5.7 1.4 1 0 0 1 1 1 0 p25-alpha PhoPQ_related PF10142.9 CBY11978.1 - 7.2e-95 317.7 0.8 8.9e-95 317.4 0.8 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Hydrolase_4 PF12146.8 CBY11978.1 - 0.0081 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY11978.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY11978.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family RPN13_C PF16550.5 CBY11978.1 - 0.19 11.9 0.0 0.58 10.3 0.0 1.7 2 0 0 2 2 2 0 UCH-binding domain PRA1 PF03208.19 CBY11979.1 - 4.3e-26 91.3 0.3 5.4e-26 90.9 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein 2TM PF13239.6 CBY11979.1 - 7.4 7.0 7.4 38 4.7 7.4 2.0 1 1 0 1 1 1 0 2TM domain DUF726 PF05277.12 CBY11980.1 - 2.9e-97 325.7 2.8 4e-97 325.2 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SAVED PF18145.1 CBY11980.1 - 0.003 17.4 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 SMODS-associated and fused to various effectors sensor domain DUF900 PF05990.12 CBY11980.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2207 PF09972.9 CBY11980.1 - 0.016 14.0 0.4 0.024 13.4 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3040 PF11239.8 CBY11980.1 - 0.028 14.7 0.2 0.028 14.7 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) ETRAMP PF09716.10 CBY11980.1 - 0.046 13.8 0.3 0.046 13.8 0.3 2.4 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) CBP_BcsR PF10945.8 CBY11980.1 - 0.14 11.6 0.2 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR Phage_holin_3_6 PF07332.11 CBY11980.1 - 0.26 11.4 8.4 0.42 10.7 4.6 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Mito_carr PF00153.27 CBY11981.1 - 2.3e-44 149.2 6.9 1.2e-17 63.5 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Snurportin1 PF11538.8 CBY11982.1 - 0.0083 16.3 4.8 0.019 15.1 4.8 1.6 1 0 0 1 1 1 1 Snurportin1 Ig_3 PF13927.6 CBY11983.1 - 7.7e-14 52.1 4.6 0.00042 20.9 0.1 6.5 6 1 0 6 6 6 3 Immunoglobulin domain Ig_2 PF13895.6 CBY11983.1 - 3.1e-11 43.5 0.5 0.14 12.5 0.1 5.3 6 0 0 6 6 6 4 Immunoglobulin domain C2-set_2 PF08205.12 CBY11983.1 - 1.4e-10 41.1 9.7 3.3e-05 23.9 0.7 5.7 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 CBY11983.1 - 3.5e-06 27.1 12.4 0.0011 19.1 0.6 6.4 6 2 0 6 6 6 2 Immunoglobulin domain DUF4198 PF10670.9 CBY11983.1 - 0.096 13.0 0.0 23 5.3 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4198) MFS_1 PF07690.16 CBY11984.1 - 1.2e-23 83.6 31.8 2.8e-23 82.4 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY11984.1 - 0.0012 17.8 18.9 0.0022 16.9 9.2 3.3 1 1 2 3 3 3 1 MFS_1 like family MFS_1 PF07690.16 CBY11985.1 - 5.5e-21 74.9 34.2 5.5e-21 74.9 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY11985.1 - 4.3e-05 22.6 0.5 4.3e-05 22.6 0.5 2.8 1 1 0 2 2 2 1 MFS_1 like family MIP PF00230.20 CBY11987.1 - 2e-27 96.4 13.6 3.1e-27 95.8 13.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein TIMELESS_C PF05029.13 CBY11988.1 - 6.8e-11 42.0 0.2 6.8e-11 42.0 0.2 2.2 3 0 0 3 3 3 1 Timeless protein C terminal region Halo_GVPC PF05465.13 CBY11988.1 - 0.041 14.1 0.5 0.11 12.7 0.5 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat TORC_N PF12884.7 CBY11988.1 - 0.35 11.7 3.9 3.8 8.4 3.2 2.7 2 2 0 2 2 2 0 Transducer of regulated CREB activity, N terminus DUF4153 PF13687.6 CBY11989.1 - 0.0014 18.3 6.2 0.0019 17.9 6.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4153) TMEM192 PF14802.6 CBY11989.1 - 0.0031 16.6 2.4 0.0039 16.3 2.4 1.1 1 0 0 1 1 1 1 TMEM192 family DUF2206 PF09971.9 CBY11989.1 - 0.01 14.6 6.4 0.012 14.3 6.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) MASE4 PF17158.4 CBY11989.1 - 0.05 12.9 10.8 0.022 14.0 6.2 1.9 1 1 1 2 2 2 0 Membrane-associated sensor, integral membrane domain DUF202 PF02656.15 CBY11989.1 - 0.2 12.1 4.3 0.28 11.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF4131 PF13567.6 CBY11989.1 - 0.46 10.1 3.7 0.25 11.0 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) TssN PF17555.2 CBY11989.1 - 0.48 9.8 6.4 0.65 9.3 6.4 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN SNF5 PF04855.12 CBY11991.1 - 2.1e-54 184.8 0.2 5.4e-29 101.7 0.1 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 EF-hand_7 PF13499.6 CBY11992.1 - 0.00011 22.5 0.1 0.00073 19.9 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY11992.1 - 0.0014 18.4 0.1 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY11992.1 - 0.0015 17.9 1.5 0.022 14.3 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 CBY11992.1 - 0.054 13.0 1.8 3.1 7.5 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 CBY11992.1 - 0.059 13.2 0.2 12 5.8 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair Adap_comp_sub PF00928.21 CBY11993.1 - 2.7e-57 194.2 0.3 3.5e-57 193.8 0.3 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBY11993.1 - 0.0063 16.4 0.4 0.012 15.5 0.4 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Thymidylat_synt PF00303.19 CBY11993.1 - 0.14 11.2 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Thymidylate synthase Methyltransf_23 PF13489.6 CBY11994.1 - 2.1e-17 63.4 0.0 3.8e-17 62.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY11994.1 - 1.7e-12 47.9 0.2 5.8e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY11994.1 - 3.5e-12 46.9 0.1 3.5e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY11994.1 - 1.4e-09 37.9 0.0 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY11994.1 - 2.6e-08 34.4 0.2 1.8e-07 31.7 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 CBY11994.1 - 0.00018 21.1 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CBY11994.1 - 0.019 14.2 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 CBY11994.1 - 0.048 13.2 0.3 0.33 10.4 0.1 2.3 2 1 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_24 PF13578.6 CBY11994.1 - 0.069 14.2 0.0 0.19 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Baculo_PEP_C PF04513.12 CBY11995.1 - 0.18 11.8 2.7 1.7 8.7 0.1 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3644 PF12358.8 CBY11995.1 - 6.2 7.4 10.1 0.61 10.6 3.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3644) Spectrin PF00435.21 CBY11997.1 - 2.3e-46 156.6 70.2 1.5e-16 60.8 9.5 7.5 6 1 1 7 7 7 6 Spectrin repeat CH PF00307.31 CBY11997.1 - 2.7e-45 153.0 0.7 8.4e-22 77.4 0.0 3.7 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBY11997.1 - 1.2e-11 44.3 0.0 4.1e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 CBY11997.1 - 0.022 14.9 5.8 0.32 11.1 0.0 4.6 5 0 0 5 5 5 0 CH-like domain in sperm protein DUF4717 PF15838.5 CBY11997.1 - 0.046 13.7 1.1 6.1 6.9 0.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4717) NPV_P10 PF05531.12 CBY11997.1 - 8.7 6.9 24.9 2.9 8.4 0.7 6.0 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 CBY11998.1 - 1.7e-13 51.0 1.6 2e-12 47.5 1.7 1.9 2 0 0 2 2 2 1 Spectrin repeat ABC_tran_CTD PF16326.5 CBY11998.1 - 0.0012 19.0 4.4 0.0019 18.4 4.4 1.3 1 0 0 1 1 1 1 ABC transporter C-terminal domain WXG100 PF06013.12 CBY11998.1 - 0.0037 17.5 1.6 0.0074 16.5 1.6 1.5 1 0 0 1 1 1 1 Proteins of 100 residues with WXG FlaC_arch PF05377.11 CBY11998.1 - 0.0044 17.4 0.1 1.4 9.4 0.0 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 CBY11998.1 - 0.0047 17.1 0.3 0.0072 16.5 0.3 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DNA_ligase_A_N PF04675.14 CBY11998.1 - 0.014 15.7 0.5 0.017 15.4 0.5 1.1 1 0 0 1 1 1 0 DNA ligase N terminus Rootletin PF15035.6 CBY11998.1 - 0.018 15.0 0.5 0.02 14.9 0.5 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.19 CBY11998.1 - 0.019 12.9 0.9 0.021 12.8 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 CBY11998.1 - 0.02 15.4 0.3 0.037 14.5 0.2 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 CBY11998.1 - 0.021 15.3 0.8 0.65 10.4 0.3 2.1 1 1 1 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.12 CBY11998.1 - 0.031 14.3 1.0 2 8.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMCO5 PF14992.6 CBY11998.1 - 0.037 13.6 0.2 0.042 13.4 0.2 1.1 1 0 0 1 1 1 0 TMCO5 family GPS2_interact PF15784.5 CBY11998.1 - 0.052 14.0 1.4 0.76 10.3 0.0 2.1 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain UPF0242 PF06785.11 CBY11998.1 - 0.058 13.5 0.4 0.075 13.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 CBY11998.1 - 0.06 13.6 1.8 0.22 11.8 1.6 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 CBY11998.1 - 0.15 12.3 4.2 0.13 12.5 2.3 1.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Csm1_N PF18504.1 CBY11998.1 - 0.22 11.9 3.4 3.8 7.9 0.1 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain PilO PF04350.13 CBY11998.1 - 0.23 11.6 3.2 0.51 10.5 2.1 2.1 2 1 0 2 2 2 0 Pilus assembly protein, PilO Trypsin PF00089.26 CBY11999.1 - 4.7e-53 180.2 5.7 6.3e-53 179.8 5.7 1.2 1 0 0 1 1 1 1 Trypsin Zona_pellucida PF00100.23 CBY11999.1 - 4.2e-12 46.4 0.0 7.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Trypsin_2 PF13365.6 CBY11999.1 - 0.00032 21.6 0.1 0.00088 20.2 0.1 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain IFP_35_N PF07334.13 CBY12000.1 - 0.064 13.3 1.1 0.064 13.3 1.1 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Gly_radical PF01228.21 CBY12000.1 - 1.1 9.8 4.6 5.8 7.5 0.8 2.5 1 1 1 2 2 2 0 Glycine radical RT_RNaseH PF17917.1 CBY12002.1 - 1.2e-29 102.6 0.0 1.8e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY12002.1 - 5.5e-25 87.3 0.0 9.3e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Torus PF16131.5 CBY12004.1 - 0.032 14.9 0.2 0.032 14.9 0.2 2.2 2 1 0 2 2 2 0 Torus domain DUF445 PF04286.12 CBY12004.1 - 0.12 12.2 2.4 0.74 9.6 2.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Ly49 PF08391.10 CBY12004.1 - 0.21 11.9 2.0 0.27 11.6 0.2 1.9 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF3106 PF11304.8 CBY12008.1 - 0.71 10.4 8.4 0.12 12.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) AbiJ_NTD4 PF18863.1 CBY12009.1 - 0.032 14.7 0.8 0.062 13.8 0.8 1.4 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 BAF1_ABF1 PF04684.13 CBY12010.1 - 0.008 15.3 0.0 0.0097 15.0 0.0 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Plasmod_MYXSPDY PF07981.11 CBY12011.1 - 0.12 12.4 0.5 15 5.8 0.1 2.5 2 0 0 2 2 2 0 Plasmodium repeat_MYXSPDY DnaG_DnaB_bind PF08278.11 CBY12012.1 - 1.6 9.3 4.9 1.8 9.1 3.1 2.0 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding DUF1707 PF08044.11 CBY12013.1 - 0.0027 17.7 0.1 0.0053 16.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) HEM4 PF02602.15 CBY12013.1 - 0.095 12.0 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD RVT_1 PF00078.27 CBY12015.1 - 9.4e-10 38.4 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 CBY12016.1 - 1.3e-09 38.0 0.0 2.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family SGL PF08450.12 CBY12017.1 - 0.08 12.5 0.0 3.6 7.1 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Kelch_5 PF13854.6 CBY12017.1 - 0.13 12.2 0.2 4.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Defensin_big PF14862.6 CBY12019.1 - 0.078 13.3 0.7 0.13 12.6 0.7 1.7 1 0 0 1 1 1 0 Big defensin Cg6151-P PF10233.9 CBY12020.1 - 4e-09 36.8 7.8 5.4e-09 36.4 7.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Tmemb_40 PF10160.9 CBY12020.1 - 0.0038 16.7 2.3 0.0042 16.6 2.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF4133 PF13571.6 CBY12020.1 - 1 9.7 6.7 6.4 7.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Galactosyl_T PF01762.21 CBY12021.1 - 1.5e-16 60.8 0.0 8.8e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 Galactosyltransferase TTL PF03133.15 CBY12022.1 - 7.1e-45 153.4 1.5 8.7e-45 153.1 1.5 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY12022.1 - 0.00036 19.9 0.2 0.0091 15.3 0.0 2.5 2 1 0 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY12022.1 - 0.077 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp FlgM PF04316.13 CBY12023.1 - 0.0061 16.9 1.1 0.0089 16.4 0.1 1.8 2 1 0 2 2 2 1 Anti-sigma-28 factor, FlgM PQQ PF01011.21 CBY12024.1 - 0.00055 19.7 0.3 0.0092 15.9 0.2 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat TSP_1 PF00090.19 CBY12024.1 - 0.0023 18.1 2.7 0.0023 18.1 2.7 4.4 4 0 0 4 4 4 1 Thrombospondin type 1 domain PQQ_2 PF13360.6 CBY12024.1 - 0.061 12.9 0.2 0.78 9.3 0.1 2.5 2 1 0 2 2 2 0 PQQ-like domain Bacteriocin_II PF01721.18 CBY12024.1 - 1.8 8.8 9.0 0.75 9.9 0.2 3.7 3 0 0 3 3 3 0 Class II bacteriocin Sushi PF00084.20 CBY12024.1 - 7.9 7.2 8.4 1 10.0 2.0 3.1 3 0 0 3 3 3 0 Sushi repeat (SCR repeat) EF-hand_7 PF13499.6 CBY12025.1 - 5.1e-19 68.5 6.1 3.6e-11 43.3 3.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY12025.1 - 2.1e-17 61.3 11.2 7.3e-06 25.2 2.3 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBY12025.1 - 1.3e-14 52.8 6.8 1.6e-06 27.6 0.2 4.6 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBY12025.1 - 5.5e-13 48.5 11.9 4.5e-09 36.0 1.4 4.3 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CBY12025.1 - 3.3e-10 40.1 0.6 6.4e-06 26.4 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY12025.1 - 4.4e-07 29.1 7.9 3.5e-05 23.1 0.6 3.7 3 0 0 3 3 3 1 EF hand DUF1456 PF07308.13 CBY12025.1 - 0.012 15.9 0.7 7.2 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) SPARC_Ca_bdg PF10591.9 CBY12025.1 - 0.025 14.9 0.9 0.13 12.5 0.2 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBY12025.1 - 0.038 14.8 0.1 1.6 9.6 0.0 2.1 1 1 0 2 2 2 0 EF-hand domain UPF0154 PF03672.13 CBY12025.1 - 0.051 13.6 0.2 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 CBY12025.1 - 0.062 13.6 0.3 0.52 10.7 0.1 2.5 1 1 0 2 2 2 0 EF-hand domain PMBR PF09373.10 CBY12025.1 - 0.16 12.2 0.0 12 6.3 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat VWD PF00094.25 CBY12026.1 - 1.2e-68 230.3 18.4 1.7e-20 73.9 0.2 5.5 4 1 0 4 4 4 4 von Willebrand factor type D domain C8 PF08742.11 CBY12026.1 - 3.9e-13 49.6 40.2 3.5e-06 27.3 3.1 8.8 9 1 1 10 10 10 4 C8 domain TIL PF01826.17 CBY12026.1 - 8.9e-13 48.3 65.4 3.2e-07 30.5 8.4 11.9 11 2 1 12 12 12 4 Trypsin Inhibitor like cysteine rich domain DUF2600 PF10776.9 CBY12026.1 - 0.14 11.0 1.2 9.4 5.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2600) DUF5464 PF17552.2 CBY12026.1 - 1 9.7 5.9 35 4.8 0.2 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5464) Kelch_6 PF13964.6 CBY12027.1 - 5.1e-06 26.6 1.0 0.02 15.2 0.1 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CBY12027.1 - 6.5e-06 25.9 2.7 0.0072 16.3 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY12027.1 - 0.00079 19.4 0.9 1.3 9.0 0.1 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY12027.1 - 0.0017 17.9 0.4 0.55 9.9 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Lactamase_B_6 PF16661.5 CBY12027.1 - 0.0093 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Kelch_3 PF13415.6 CBY12027.1 - 0.16 12.3 0.5 18 5.7 0.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain zf-C4 PF00105.18 CBY12032.1 - 5.3e-11 42.8 12.5 1.4e-10 41.5 12.5 1.7 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) Med3 PF11593.8 CBY12032.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal C1_2 PF03107.16 CBY12032.1 - 2.5 8.5 6.5 2.3 8.6 0.9 2.6 2 0 0 2 2 2 0 C1 domain 4HB_MCP_1 PF12729.7 CBY12034.1 - 0.0074 15.9 1.4 0.01 15.4 0.9 1.6 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction Zona_pellucida PF00100.23 CBY12035.1 - 1.6e-33 116.6 0.2 2.6e-33 115.9 0.2 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Astacin PF01400.24 CBY12036.1 - 3.2e-20 72.6 0.0 3.2e-18 66.0 0.0 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_3 PF12947.7 CBY12036.1 - 1.2e-11 44.5 24.8 5.5e-07 29.7 9.4 3.1 2 0 0 2 2 2 2 EGF domain EGF_CA PF07645.15 CBY12036.1 - 2.5e-07 30.8 24.1 2.4e-06 27.6 6.7 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF PF00008.27 CBY12036.1 - 2.9e-07 30.6 24.7 0.0011 19.3 8.0 3.8 3 0 0 3 3 3 2 EGF-like domain cEGF PF12662.7 CBY12036.1 - 0.023 14.6 9.4 0.88 9.6 0.1 3.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.7 CBY12036.1 - 0.29 11.8 24.1 0.091 13.4 3.3 4.3 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY12036.1 - 9.5 6.4 25.3 0.47 10.5 6.7 2.9 3 0 0 3 3 3 0 MSP1 EGF domain 1 ubiquitin PF00240.23 CBY12037.1 - 0.00068 19.3 0.0 0.0055 16.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Sigma70_r3 PF04539.16 CBY12037.1 - 0.042 13.9 0.1 0.073 13.2 0.1 1.3 1 0 0 1 1 1 0 Sigma-70 region 3 SH3_1 PF00018.28 CBY12038.1 - 3.9e-10 39.2 0.2 5.7e-10 38.6 0.2 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY12038.1 - 1e-08 34.9 0.1 1.5e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY12038.1 - 1.8e-08 33.9 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CBY12038.1 - 0.0097 16.2 0.3 0.015 15.6 0.3 1.2 1 0 0 1 1 1 1 Bacterial SH3 domain UBA PF00627.31 CBY12040.1 - 4e-08 33.0 0.4 0.00025 20.9 0.1 2.8 3 0 0 3 3 3 2 UBA/TS-N domain UCH PF00443.29 CBY12040.1 - 7.8e-08 32.1 11.0 2.1e-06 27.4 11.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 CBY12040.1 - 0.12 12.3 0.1 0.43 10.4 0.1 2.0 2 0 0 2 2 2 0 UBA-like domain PhoLip_ATPase_N PF16209.5 CBY12040.1 - 0.17 11.6 1.3 0.35 10.6 1.3 1.5 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal Atypical_Card PF18461.1 CBY12040.1 - 0.44 10.8 3.9 43 4.4 0.1 3.9 4 0 0 4 4 4 0 Atypical caspase recruitment domain Linker_histone PF00538.19 CBY12040.1 - 0.9 9.9 6.7 5.7 7.4 0.0 3.3 3 0 0 3 3 3 0 linker histone H1 and H5 family DUF3298 PF11738.8 CBY12040.1 - 0.95 10.5 4.7 2.7 9.1 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3298) Sulfatase PF00884.23 CBY12041.1 - 8.3e-58 196.2 0.2 1.4e-57 195.5 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY12041.1 - 6.5e-05 22.7 1.8 0.00011 21.9 0.1 2.1 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 CBY12041.1 - 0.0058 17.4 2.8 0.033 14.9 0.5 2.8 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 CBY12041.1 - 0.034 14.4 2.8 0.59 10.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4976) Trypsin PF00089.26 CBY12042.1 - 5e-53 180.2 0.8 6.9e-53 179.7 0.8 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY12042.1 - 2.7e-10 41.4 0.0 4.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY12042.1 - 0.0095 15.5 0.2 1.6 8.2 0.0 2.2 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 CBY12042.1 - 0.086 13.2 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Phospholip_A2_1 PF00068.19 CBY12043.1 - 7.4e-16 58.6 11.3 7.4e-16 58.6 11.3 2.0 1 1 0 2 2 2 1 Phospholipase A2 DUF4618 PF15397.6 CBY12045.1 - 0.0074 15.7 0.4 0.014 14.8 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Tmemb_cc2 PF10267.9 CBY12046.1 - 0.28 10.3 2.9 0.8 8.8 2.9 1.8 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein IQ PF00612.27 CBY12047.1 - 1.3e-11 43.2 22.7 0.00022 20.8 1.5 4.2 5 0 0 5 5 5 3 IQ calmodulin-binding motif DUF3347 PF11827.8 CBY12047.1 - 0.12 12.5 7.8 0.21 11.8 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) RNA_pol_Rpb5_N PF03871.14 CBY12047.1 - 0.32 11.6 5.4 0.096 13.3 2.3 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain zf-RING_2 PF13639.6 CBY12050.1 - 3.1e-05 24.2 3.7 5e-05 23.6 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY12050.1 - 0.0022 18.0 2.1 0.0038 17.2 2.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY12050.1 - 0.074 12.9 3.0 0.13 12.1 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY12050.1 - 0.076 12.9 4.4 0.15 11.9 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY12050.1 - 0.49 10.4 3.4 0.82 9.7 3.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 CBY12050.1 - 5.2 7.4 6.6 25 5.3 6.5 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger domain RHD_dimer PF16179.5 CBY12051.1 - 2.5e-19 69.2 0.2 4.8e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 CBY12051.1 - 6.1e-11 42.6 1.4 1.7e-09 37.8 1.4 2.4 1 1 0 1 1 1 1 Rel homology DNA-binding domain TIG PF01833.24 CBY12051.1 - 8.5e-06 25.8 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain FCH PF00611.23 CBY12052.1 - 5.1e-11 42.7 1.5 2.2e-10 40.7 0.3 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Cor1 PF04803.12 CBY12052.1 - 0.0078 16.4 5.5 0.015 15.5 0.2 3.1 2 2 1 3 3 3 1 Cor1/Xlr/Xmr conserved region PLAC8 PF04749.17 CBY12052.1 - 0.011 16.7 6.8 0.022 15.8 6.8 1.4 1 0 0 1 1 1 0 PLAC8 family BRE1 PF08647.11 CBY12052.1 - 0.02 14.9 2.6 0.02 14.9 2.6 3.3 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase tRNA_anti-like PF12869.7 CBY12052.1 - 0.03 13.9 0.1 0.085 12.5 0.1 1.9 1 1 0 1 1 1 0 tRNA_anti-like HCMV_UL139 PF12507.8 CBY12052.1 - 0.073 13.4 1.1 0.43 11.0 0.2 2.8 2 2 0 2 2 2 0 Human Cytomegalovirus UL139 protein CtIP_N PF10482.9 CBY12052.1 - 0.66 10.0 4.0 4.7 7.3 1.0 2.6 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain PMP22_Claudin PF00822.20 CBY12053.1 - 1.4e-10 41.3 6.2 2.3e-10 40.6 6.2 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY12053.1 - 3.8e-06 27.2 1.3 7.2e-06 26.3 1.3 1.4 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein 7tm_3 PF00003.22 CBY12053.1 - 0.00045 20.0 5.7 0.0007 19.4 5.7 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Claudin_2 PF13903.6 CBY12053.1 - 0.0014 18.5 13.4 0.0033 17.2 12.9 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction LrgA PF03788.14 CBY12053.1 - 0.018 15.0 1.5 1.3 9.1 0.6 2.3 2 0 0 2 2 2 0 LrgA family YoqO PF14037.6 CBY12053.1 - 0.12 12.9 0.5 0.12 12.9 0.5 2.1 3 0 0 3 3 3 0 YoqO-like protein 7TMR-DISM_7TM PF07695.11 CBY12053.1 - 0.14 12.1 14.3 0.18 11.7 13.5 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF2627 PF11118.8 CBY12053.1 - 0.24 12.0 0.1 0.24 12.0 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2627) 7TM-7TMR_HD PF07698.11 CBY12053.1 - 0.74 9.5 9.6 0.52 10.0 7.3 1.7 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase DUF1218 PF06749.12 CBY12053.1 - 0.93 10.1 7.6 20 5.8 4.2 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Tmemb_170 PF10190.9 CBY12053.1 - 1.3 9.5 7.4 0.21 12.0 3.4 1.7 2 1 0 2 2 1 0 Putative transmembrane protein 170 Claudin_3 PF06653.11 CBY12053.1 - 2.6 8.0 10.4 11 6.0 10.6 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like YwiC PF14256.6 CBY12053.1 - 4.6 7.6 11.3 1.1 9.6 2.4 2.7 2 1 1 3 3 3 0 YwiC-like protein DUF3792 PF12670.7 CBY12053.1 - 4.8 7.4 12.8 0.6 10.3 7.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) D5_N PF08706.11 CBY12054.1 - 0.012 15.9 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 D5 N terminal like O-FucT PF10250.9 CBY12055.1 - 0.014 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.9 CBY12056.1 - 0.0028 17.4 0.1 0.0041 16.9 0.1 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Sad1_UNC PF07738.13 CBY12057.1 - 1.9e-30 105.6 0.0 3.8e-30 104.6 0.0 1.5 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Pkinase PF00069.25 CBY12058.1 - 5.5e-47 160.3 0.0 7.6e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12058.1 - 7.3e-18 64.8 0.0 1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY12058.1 - 1.3e-08 34.5 0.0 2.8e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY12058.1 - 9.8e-06 25.1 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY12058.1 - 1.8e-05 23.9 0.2 3.8e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY12058.1 - 0.00081 18.3 0.1 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBY12058.1 - 0.0079 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY12058.1 - 0.01 15.4 0.6 0.015 14.9 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Lectin_C PF00059.21 CBY12060.1 - 0.021 15.5 0.5 0.17 12.6 0.1 2.6 1 1 1 2 2 2 0 Lectin C-type domain Biopterin_H PF00351.21 CBY12061.1 - 1.4e-97 326.7 0.0 1.8e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase pKID PF02173.17 CBY12061.1 - 0.48 9.9 4.4 1.2 8.7 4.4 1.7 1 0 0 1 1 1 0 pKID domain Carb_anhydrase PF00194.21 CBY12062.1 - 9.3e-60 202.3 0.0 1.1e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Thioredoxin PF00085.20 CBY12063.1 - 1.1e-25 89.6 0.0 1.3e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Zona_pellucida PF00100.23 CBY12063.1 - 2.1e-25 90.0 2.8 3e-25 89.5 2.8 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Thioredoxin_2 PF13098.6 CBY12063.1 - 0.0018 18.7 1.5 2.3 8.7 0.1 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY12063.1 - 0.023 14.9 0.6 1.9 8.7 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.6 CBY12063.1 - 0.07 13.5 0.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like Glutaredoxin PF00462.24 CBY12063.1 - 0.59 10.4 2.1 10 6.4 0.0 2.9 3 0 0 3 3 3 0 Glutaredoxin GTP_EFTU PF00009.27 CBY12064.1 - 5.6e-55 185.9 0.5 5.6e-55 185.9 0.5 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CBY12064.1 - 1.3e-13 51.1 2.0 1.3e-13 51.1 2.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 CBY12064.1 - 6.7e-11 42.5 0.1 2.3e-10 40.7 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CBY12064.1 - 0.0001 22.3 0.1 0.00022 21.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Aminotran_5 PF00266.19 CBY12065.1 - 5.5e-97 325.0 0.0 6.7e-97 324.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBY12065.1 - 7.9e-10 38.5 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CBY12065.1 - 3.6e-06 26.5 0.0 5.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CBY12065.1 - 0.0024 16.5 0.0 0.0035 15.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 CBY12065.1 - 0.018 13.7 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_S24e PF01282.19 CBY12065.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S24e Transmemb_17 PF09799.9 CBY12066.1 - 1.8e-14 54.2 8.8 2.5e-14 53.8 8.1 1.5 2 0 0 2 2 2 1 Predicted membrane protein DUF2975 PF11188.8 CBY12066.1 - 0.39 10.6 5.7 0.74 9.7 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) NAF PF03822.14 CBY12067.1 - 0.028 14.6 1.3 0.27 11.5 0.2 2.7 2 0 0 2 2 2 0 NAF domain DUF3377 PF11857.8 CBY12067.1 - 0.034 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3726 PF12525.8 CBY12067.1 - 0.13 12.3 2.1 0.31 11.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) Ldh_1_C PF02866.18 CBY12067.1 - 1.1 9.2 4.5 3.1 7.7 0.1 2.8 3 0 0 3 3 3 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sod_Cu PF00080.20 CBY12068.1 - 6.7e-57 191.6 13.5 1.7e-29 102.8 3.4 2.1 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) RPN1_RPN2_N PF17781.1 CBY12068.1 - 2.7e-14 53.3 0.1 3.5e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain MCM PF00493.23 CBY12069.1 - 1.1e-94 315.7 0.0 1.7e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY12069.1 - 2.2e-36 124.5 0.1 4.3e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBY12069.1 - 1.2e-26 93.0 1.2 6.5e-25 87.4 0.5 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CBY12069.1 - 1.4e-14 54.5 1.2 1.4e-14 54.5 1.2 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY12069.1 - 1.5e-08 34.3 0.1 9.5e-06 25.1 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY12069.1 - 9.6e-08 32.1 0.0 2.3e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY12069.1 - 7.1e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CBY12069.1 - 0.09 13.2 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol_B PF00136.21 CBY12070.1 - 8.1e-111 370.9 0.2 1.7e-110 369.9 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBY12070.1 - 8.1e-38 130.4 0.0 2.5e-37 128.8 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 CBY12070.1 - 3.9e-15 56.1 1.3 1e-14 54.7 1.3 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 CBY12070.1 - 5.8e-08 32.7 10.5 5.9e-08 32.7 6.5 3.0 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Pkinase PF00069.25 CBY12071.1 - 1.1e-34 120.0 0.1 1.9e-34 119.2 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12071.1 - 5.1e-25 88.2 0.0 8.5e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY12071.1 - 1.7e-11 44.0 0.0 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY12071.1 - 0.00039 19.3 2.0 0.0088 14.9 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Phage_pRha PF09669.10 CBY12071.1 - 7.2 7.3 7.2 8 7.1 5.0 2.3 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) DUF4499 PF14934.6 CBY12072.1 - 2.5e-12 46.9 0.2 3.9e-12 46.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) TSP_1 PF00090.19 CBY12073.1 - 1.7e-112 367.5 396.3 2.1e-10 40.7 2.5 31.5 29 3 1 30 30 30 28 Thrombospondin type 1 domain DUF4499 PF14934.6 CBY12074.1 - 5.8e-05 23.3 1.6 7.4e-05 23.0 0.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) Sulfotransfer_2 PF03567.14 CBY12075.1 - 1e-32 114.0 0.0 1.2e-32 113.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family CdiI_2 PF18593.1 CBY12075.1 - 0.14 12.8 0.1 0.37 11.5 0.1 1.7 1 0 0 1 1 1 0 CdiI immunity protein CS PF04969.16 CBY12076.1 - 6.7e-14 52.7 0.1 2.3e-13 50.9 0.1 2.0 1 0 0 1 1 1 1 CS domain EXOSC1 PF10447.9 CBY12077.1 - 2.1e-14 54.1 1.6 6.3e-10 39.6 0.2 2.5 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CBY12077.1 - 4.6e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Tam41_Mmp37 PF09139.11 CBY12078.1 - 3.1e-60 204.3 0.6 1.4e-58 198.9 0.6 2.2 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Collagen PF01391.18 CBY12079.1 - 2.6e-06 27.1 17.9 6.3e-06 25.9 17.9 1.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DivIC PF04977.15 CBY12079.1 - 1.2 8.9 5.6 0.33 10.7 0.8 2.3 2 1 1 3 3 3 0 Septum formation initiator Nsp1_C PF05064.13 CBY12079.1 - 1.9 8.3 5.3 0.95 9.3 0.3 2.2 2 1 0 2 2 2 0 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.9 CBY12079.1 - 2.5 8.1 7.9 4 7.4 0.9 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XhlA PF10779.9 CBY12079.1 - 4.2 7.6 8.5 0.43 10.8 0.9 2.6 2 2 0 2 2 2 0 Haemolysin XhlA Na_H_Exchanger PF00999.21 CBY12080.1 - 5.5e-71 239.4 34.6 7.2e-71 239.0 34.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Trefoil PF00088.18 CBY12081.1 - 3.6e-08 33.2 5.6 7.3e-08 32.2 5.6 1.6 1 0 0 1 1 1 1 Trefoil (P-type) domain GREB1 PF15782.5 CBY12081.1 - 5.8 3.9 12.6 7.1 3.6 12.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-RING_5 PF14634.6 CBY12083.1 - 5.4e-08 32.7 13.9 5.4e-08 32.7 13.9 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY12083.1 - 2.6e-05 24.2 22.5 0.00032 20.7 5.6 3.8 3 1 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 CBY12083.1 - 5.1e-05 23.5 12.0 5.1e-05 23.5 12.0 2.9 2 1 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBY12083.1 - 0.00015 21.6 9.1 0.00015 21.6 9.1 3.1 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY12083.1 - 0.00017 21.4 10.0 0.00017 21.4 10.0 4.1 3 2 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY12083.1 - 0.00039 20.1 10.3 0.00039 20.1 10.3 3.1 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CBY12083.1 - 0.0026 17.5 12.3 0.0026 17.5 12.3 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CBY12083.1 - 0.015 14.7 7.7 0.015 14.7 7.7 3.6 1 1 3 4 4 4 0 Rtf2 RING-finger PKcGMP_CC PF16808.5 CBY12085.1 - 1.1 9.2 6.5 2.1 8.2 6.5 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lipase PF00151.19 CBY12086.1 - 1.3e-22 80.6 0.0 1.6e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 CBY12086.1 - 0.0028 18.3 0.0 0.0047 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 CBY12086.1 - 0.0037 16.8 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.8 CBY12086.1 - 0.038 13.6 0.3 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 CBY12086.1 - 0.098 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 CBY12086.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Branch PF02485.21 CBY12087.1 - 5.2e-48 163.7 0.1 7.1e-48 163.3 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Cyclin_N PF00134.23 CBY12088.1 - 8.1e-30 103.2 3.4 1.2e-29 102.6 3.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY12088.1 - 5.9e-07 29.6 0.0 2e-06 27.9 0.0 1.9 2 1 0 2 2 2 1 Cyclin, C-terminal domain TFIIB_C_1 PF18542.1 CBY12088.1 - 0.051 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 EGF_CA PF07645.15 CBY12089.1 - 4.8e-148 481.2 316.2 2.5e-10 40.4 10.6 19.8 17 2 2 19 19 19 18 Calcium-binding EGF domain EGF_3 PF12947.7 CBY12089.1 - 1.3e-114 374.1 312.6 1.2e-10 41.4 10.1 19.9 20 0 0 20 20 20 18 EGF domain cEGF PF12662.7 CBY12089.1 - 2.2e-70 232.1 202.1 3.2e-07 30.2 3.4 20.1 20 1 0 20 20 20 15 Complement Clr-like EGF-like EGF PF00008.27 CBY12089.1 - 1.7e-40 136.9 270.9 4.9e-05 23.5 5.1 20.8 20 0 0 20 20 20 15 EGF-like domain EGF_MSP1_1 PF12946.7 CBY12089.1 - 2e-25 88.5 228.1 3.5e-05 23.7 6.0 17.9 17 1 0 17 17 17 13 MSP1 EGF domain 1 hEGF PF12661.7 CBY12089.1 - 1.7e-21 76.0 216.2 0.00048 20.6 4.5 21.8 21 0 0 21 21 21 13 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY12089.1 - 8.2e-19 67.6 268.6 0.00073 19.8 9.9 20.2 13 5 7 20 20 20 14 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY12089.1 - 2.6e-09 37.2 229.6 0.0041 17.4 4.0 19.6 18 1 0 19 19 19 10 Pvs28 EGF domain EGF_2 PF07974.13 CBY12089.1 - 0.00078 19.8 7.7 0.00078 19.8 7.7 18.1 18 0 0 18 18 18 5 EGF-like domain zf-RING_5 PF14634.6 CBY12090.1 - 2.8e-08 33.6 15.7 2.8e-08 33.6 15.7 2.5 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY12090.1 - 0.0001 22.6 15.8 0.0001 22.6 15.8 2.7 3 0 0 3 3 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBY12090.1 - 0.012 15.4 12.6 0.012 15.4 12.6 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY12090.1 - 0.015 15.1 16.3 0.015 15.1 16.3 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY12090.1 - 0.015 15.3 11.6 0.015 15.3 11.6 2.9 2 2 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.6 CBY12090.1 - 0.017 15.0 3.0 0.017 15.0 3.0 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein APG6_N PF17675.1 CBY12090.1 - 0.075 13.6 14.4 0.081 13.5 12.9 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 CBY12090.1 - 0.18 11.4 6.3 0.25 10.9 6.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CBY12090.1 - 0.83 7.5 7.3 1.2 6.9 7.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2262 PF10020.9 CBY12090.1 - 1.8 8.9 9.0 0.45 10.9 4.2 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) Spectrin PF00435.21 CBY12090.1 - 2.2 8.8 10.0 0.27 11.7 1.4 2.4 1 1 1 2 2 2 0 Spectrin repeat TMF_TATA_bd PF12325.8 CBY12090.1 - 2.8 8.2 13.4 12 6.2 13.4 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1635 PF07795.11 CBY12090.1 - 3.8 7.3 11.8 12 5.6 11.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) DUF1664 PF07889.12 CBY12090.1 - 4.4 7.4 8.0 12 6.0 7.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 CBY12090.1 - 5.9 6.9 16.8 1.3e+02 2.6 16.8 2.5 1 1 0 1 1 1 0 Prefoldin subunit TMPIT PF07851.13 CBY12090.1 - 7.7 5.7 8.9 13 4.9 8.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein YgaB PF14182.6 CBY12090.1 - 8.3 6.9 10.0 0.37 11.2 0.9 2.7 2 1 0 3 3 3 0 YgaB-like protein Trypsin PF00089.26 CBY12091.1 - 2.2e-50 171.6 0.2 1.9e-48 165.2 0.2 2.1 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY12091.1 - 0.012 16.6 0.1 0.54 11.1 0.1 2.3 1 1 0 1 1 1 0 Trypsin-like peptidase domain Neur_chan_LBD PF02931.23 CBY12093.1 - 1.6e-59 201.0 0.7 2.4e-59 200.4 0.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY12093.1 - 2.7e-52 178.2 11.6 8.8e-39 134.0 9.4 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region O-FucT PF10250.9 CBY12094.1 - 0.0039 17.0 1.4 0.0053 16.5 0.4 1.8 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase AA_permease_2 PF13520.6 CBY12095.1 - 2.1e-57 194.9 42.2 2.1e-57 194.9 42.2 1.7 1 1 1 2 2 2 1 Amino acid permease Arteri_Gl PF00951.18 CBY12095.1 - 0.038 13.8 0.4 0.038 13.8 0.4 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Ion_trans PF00520.31 CBY12096.1 - 2.4e-25 89.2 13.8 3.9e-25 88.5 13.8 1.3 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 CBY12096.1 - 1.9e-24 85.7 2.0 3.6e-24 84.7 2.0 1.5 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.12 CBY12096.1 - 1.3e-14 53.8 12.6 3.2e-14 52.4 12.6 1.6 1 1 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.7 CBY12096.1 - 1.6e-06 28.6 0.0 0.00036 21.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY12096.1 - 0.058 13.7 0.0 7.4 7.0 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PBC PF03792.13 CBY12096.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 PBC domain Plectin PF00681.20 CBY12097.1 - 4.1e-06 26.6 0.0 0.0014 18.4 0.0 3.7 4 0 0 4 4 4 1 Plectin repeat DUF1992 PF09350.10 CBY12097.1 - 0.031 14.4 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) Sep15_SelM PF08806.11 CBY12098.1 - 0.049 13.8 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 Sep15/SelM redox domain Fur_reg_FbpA PF13076.6 CBY12098.1 - 0.078 12.7 0.6 0.38 10.5 0.0 2.3 3 0 0 3 3 3 0 Fur-regulated basic protein A Thr_dehydrat_C PF00585.18 CBY12098.1 - 0.092 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase ATP-gua_Ptrans PF00217.19 CBY12099.1 - 1.8e-59 200.8 0.0 2.2e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY12099.1 - 1.3e-23 83.2 0.0 4.2e-23 81.5 0.0 1.8 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain Sulfate_transp PF00916.20 CBY12101.1 - 4e-86 289.1 23.2 5e-86 288.8 23.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CBY12101.1 - 0.0062 16.2 0.1 0.26 10.9 0.1 2.3 1 1 0 1 1 1 1 STAS domain ABC_membrane PF00664.23 CBY12102.1 - 5.1e-36 124.7 2.5 7e-36 124.3 2.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBY12102.1 - 2e-32 112.6 0.0 1e-31 110.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CBY12102.1 - 2.3e-08 33.7 0.0 1e-07 31.7 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CBY12102.1 - 5.2e-06 25.9 0.2 0.00038 19.8 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin IstB_IS21 PF01695.17 CBY12102.1 - 0.0029 17.3 0.0 0.76 9.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 CBY12102.1 - 0.0031 18.0 1.9 0.071 13.5 0.3 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBY12102.1 - 0.004 16.9 0.4 0.049 13.3 0.4 2.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CBY12102.1 - 0.0072 16.2 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase ABC_membrane_2 PF06472.15 CBY12102.1 - 0.017 14.6 0.2 0.032 13.6 0.2 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 SRP54 PF00448.22 CBY12102.1 - 0.024 14.3 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CBY12102.1 - 0.026 14.8 0.7 0.26 11.5 0.2 2.6 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CBY12102.1 - 0.03 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 CBY12102.1 - 0.036 13.8 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CBY12102.1 - 0.041 13.4 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CBY12102.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Ploopntkinase3 PF18751.1 CBY12102.1 - 0.057 13.3 0.0 0.33 10.9 0.0 2.3 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 CBY12102.1 - 0.1 13.1 0.1 0.34 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 CBY12102.1 - 0.13 12.6 0.3 0.34 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 CBY12102.1 - 0.15 12.1 0.1 0.91 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 CBY12102.1 - 0.2 11.9 3.0 1.1 9.6 0.8 2.7 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit KH_6 PF15985.5 CBY12103.1 - 3.3e-05 24.1 0.0 9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 KH domain zf-CCCH_3 PF15663.5 CBY12104.1 - 2.8e-09 37.2 19.3 9.4e-09 35.5 4.6 2.4 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 CBY12104.1 - 2.7e-07 31.3 19.9 0.0046 17.6 0.8 3.8 1 1 3 4 4 4 3 Torus domain zf-CCCH PF00642.24 CBY12104.1 - 1e-06 28.5 30.9 0.011 15.6 5.0 4.3 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY12104.1 - 0.014 15.4 33.2 0.041 13.9 1.5 4.6 4 0 0 4 4 4 0 Zinc finger domain ASCH PF04266.14 CBY12105.1 - 1e-12 48.6 0.0 2.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 ASCH domain DUF2018 PF09442.10 CBY12105.1 - 0.063 14.2 0.5 0.13 13.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) DUF1674 PF07896.12 CBY12106.1 - 7.2e-17 61.6 4.0 9.7e-17 61.2 4.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DUF2205 PF10224.9 CBY12107.1 - 1.2e-21 76.4 0.2 1.5e-21 76.2 0.2 1.0 1 0 0 1 1 1 1 Short coiled-coil protein CENP-H PF05837.12 CBY12107.1 - 0.00028 21.2 0.2 0.00031 21.1 0.2 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) NRBF2 PF08961.10 CBY12107.1 - 0.00037 20.2 0.0 0.00037 20.2 0.0 1.1 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 CBY12107.1 - 0.0016 19.1 0.3 0.0016 19.1 0.3 1.1 1 0 0 1 1 1 1 Initiation control protein YabA bZIP_1 PF00170.21 CBY12107.1 - 0.0042 17.2 0.3 0.0059 16.7 0.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor Cep57_CLD_2 PF14197.6 CBY12107.1 - 0.0052 16.8 0.5 0.0066 16.5 0.5 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 ADIP PF11559.8 CBY12107.1 - 0.0052 16.9 0.1 0.0057 16.8 0.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding BicD PF09730.9 CBY12107.1 - 0.013 14.0 0.3 0.014 13.8 0.3 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D ZapB PF06005.12 CBY12107.1 - 0.013 15.9 1.5 0.017 15.6 1.5 1.2 1 0 0 1 1 1 0 Cell division protein ZapB FlaC_arch PF05377.11 CBY12107.1 - 0.014 15.8 0.5 0.018 15.4 0.5 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 CBY12107.1 - 0.021 15.1 1.9 1.8 8.9 0.1 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 CBY12107.1 - 0.05 13.5 3.4 3.7 7.5 3.4 2.2 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Yae1_N PF09811.9 CBY12108.1 - 8.5e-05 22.2 0.1 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal COesterase PF00135.28 CBY12109.1 - 8.2e-38 130.5 0.0 1e-37 130.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY12109.1 - 0.16 11.8 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 CBY12110.1 - 1.3e-69 235.4 0.2 2e-69 234.8 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Glyco_hydro_10 PF00331.20 CBY12110.1 - 2.2e-23 82.9 2.6 4.2e-23 82.0 2.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 CBY12110.1 - 7.3e-09 36.0 2.8 0.00017 21.8 0.3 4.4 3 1 0 3 3 3 2 Carbohydrate binding domain Abhydrolase_3 PF07859.13 CBY12110.1 - 0.00012 22.0 0.1 0.00047 20.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold ITI_HC_C PF06668.12 CBY12111.1 - 0.00069 19.3 0.0 0.0045 16.7 0.0 2.3 2 1 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Zona_pellucida PF00100.23 CBY12112.1 - 2.6e-24 86.4 2.1 3e-24 86.2 2.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain TSP_1 PF00090.19 CBY12114.1 - 3.6e-19 68.7 169.2 7.3e-09 35.7 8.0 14.4 13 4 0 13 13 13 10 Thrombospondin type 1 domain CNH PF00780.22 CBY12116.1 - 1.2e-15 57.9 0.0 1.6e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain Tudor-knot PF11717.8 CBY12116.1 - 0.22 11.4 1.8 0.42 10.5 1.0 1.8 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain CNH PF00780.22 CBY12117.1 - 0.0021 17.7 0.0 0.0023 17.6 0.0 1.1 1 0 0 1 1 1 1 CNH domain Lactamase_B PF00753.27 CBY12119.1 - 1.2e-05 25.4 2.5 0.0099 15.9 0.1 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY12119.1 - 0.026 14.1 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PUD PF03714.14 CBY12120.1 - 0.11 13.3 0.1 0.26 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial pullanase-associated domain Lectin_C PF00059.21 CBY12121.1 - 5.6e-42 142.9 23.2 1e-16 61.6 5.2 3.7 4 0 0 4 4 4 3 Lectin C-type domain ShK PF01549.24 CBY12121.1 - 1.2e-06 29.0 26.8 8.4e-06 26.2 8.3 3.9 4 0 0 4 4 4 2 ShK domain-like Gla PF00594.20 CBY12122.1 - 9.7e-08 32.1 7.2 9.7e-08 32.1 7.2 2.0 2 1 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain TSP_1 PF00090.19 CBY12122.1 - 0.0095 16.1 7.4 0.031 14.5 7.4 2.0 1 1 0 1 1 1 1 Thrombospondin type 1 domain Hema_esterase PF03996.15 CBY12123.1 - 0.086 12.6 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 Hemagglutinin esterase 7tm_1 PF00001.21 CBY12125.1 - 5.5e-20 71.8 10.3 7.3e-19 68.1 10.3 2.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CBY12125.1 - 7e-09 35.7 9.9 7e-09 35.7 9.9 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2070 PF09843.9 CBY12125.1 - 3.1 6.0 16.2 0.032 12.6 1.4 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF1980 PF09323.10 CBY12125.1 - 5.9 6.8 8.4 16 5.3 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) YbgT_YccB PF08173.11 CBY12125.1 - 6.7 6.9 7.8 0.66 10.1 2.1 2.4 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Acetyltransf_1 PF00583.25 CBY12126.1 - 1.5e-15 57.5 0.0 2.3e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY12126.1 - 3.2e-10 40.3 0.0 6.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY12126.1 - 4.9e-08 33.0 0.1 8.8e-08 32.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY12126.1 - 0.00015 21.9 0.0 0.00025 21.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY12126.1 - 0.00062 19.8 0.0 0.0033 17.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBY12126.1 - 0.00073 19.1 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 CBY12126.1 - 0.00099 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CBY12126.1 - 0.0067 17.1 0.0 0.013 16.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY12126.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CBY12126.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase COesterase PF00135.28 CBY12128.1 - 1.8e-10 40.3 0.0 1.9e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 CBY12129.1 - 1.6e-90 304.4 0.0 2.1e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY12129.1 - 5.5e-07 29.7 0.6 4.4e-06 26.7 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold CUB PF00431.20 CBY12130.1 - 2.2e-30 105.2 0.2 4.8e-17 62.3 0.1 2.6 2 0 0 2 2 2 2 CUB domain FXa_inhibition PF14670.6 CBY12130.1 - 0.0086 16.3 13.0 0.028 14.7 13.0 2.0 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SPX PF03105.19 CBY12130.1 - 0.13 12.1 5.9 0.2 11.5 5.9 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CBY12130.1 - 0.77 8.5 8.0 1.2 7.9 8.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.12 CBY12130.1 - 2.7 6.1 7.0 4.6 5.3 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 CBY12130.1 - 4.1 7.2 10.8 1.2 8.9 5.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Astacin PF01400.24 CBY12133.1 - 2.1e-23 82.9 0.0 3.9e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY12133.1 - 2.3e-18 66.1 61.2 1.6e-05 25.0 2.1 6.6 5 1 1 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.7 CBY12133.1 - 2.2e-10 40.2 23.8 0.00056 19.8 0.7 4.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY12133.1 - 4.9e-07 29.8 22.5 3.3e-05 24.0 13.1 5.6 5 0 0 5 5 5 2 EGF domain EGF PF00008.27 CBY12133.1 - 0.0071 16.6 61.5 0.016 15.5 3.8 6.2 5 1 0 5 5 5 3 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY12133.1 - 0.89 9.9 33.3 0.067 13.5 1.5 4.7 4 0 0 4 4 4 0 Pvs28 EGF domain FXa_inhibition PF14670.6 CBY12133.1 - 2.5 8.4 56.6 0.13 12.6 3.7 5.6 5 0 0 5 5 5 0 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY12133.1 - 3.3 8.5 55.6 0.07 13.8 3.5 6.1 6 0 0 6 6 6 0 Human growth factor-like EGF Pkinase PF00069.25 CBY12135.1 - 1.2e-70 237.9 0.0 2.1e-70 237.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12135.1 - 1.7e-34 119.3 0.0 3e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Glycos_transf_2 PF00535.26 CBY12135.1 - 1.5e-24 86.7 0.0 3e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CBY12135.1 - 9e-08 31.7 0.2 2.3e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY12135.1 - 2e-06 27.5 0.0 4.5e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 CBY12135.1 - 6.4e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Kinase-like PF14531.6 CBY12135.1 - 0.00041 19.7 0.1 0.1 11.9 0.0 2.3 1 1 1 2 2 2 2 Kinase-like FTA2 PF13095.6 CBY12135.1 - 0.0061 16.2 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CBY12135.1 - 0.022 13.7 0.2 0.04 12.9 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBY12135.1 - 0.1 12.5 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.28 CBY12137.1 - 2.8e-15 57.4 2.6 3.9e-15 56.9 2.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sulfotransfer_2 PF03567.14 CBY12140.1 - 9.8e-12 45.3 0.3 2.2e-11 44.1 0.3 1.6 1 0 0 1 1 1 1 Sulfotransferase family Dynactin_p22 PF07426.11 CBY12140.1 - 0.0024 17.8 0.8 0.0034 17.3 0.8 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Lectin_C PF00059.21 CBY12141.1 - 9.3e-15 55.3 1.5 9.3e-15 55.3 1.5 1.9 2 0 0 2 2 2 1 Lectin C-type domain p25-alpha PF05517.12 CBY12142.1 - 0.11 12.6 0.2 0.14 12.3 0.2 1.1 1 0 0 1 1 1 0 p25-alpha Glyco_hydro_38C PF07748.13 CBY12146.1 - 9.6e-08 32.4 0.0 9.9e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Shisa PF13908.6 CBY12147.1 - 0.069 13.4 9.6 0.031 14.5 3.2 2.8 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator ECSCR PF15820.5 CBY12147.1 - 0.093 12.6 0.5 0.94 9.3 0.0 2.6 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator WD40_3 PF15911.5 CBY12147.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 WD domain, G-beta repeat HemY_N PF07219.13 CBY12147.1 - 0.15 12.3 0.5 4.2 7.6 0.0 2.5 2 0 0 2 2 2 0 HemY protein N-terminus ATP-synt_8 PF00895.20 CBY12147.1 - 0.19 12.2 2.7 0.89 10.1 0.2 2.8 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3112 PF11309.8 CBY12147.1 - 0.7 9.3 6.3 1.9 7.9 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) Pik1 PF11522.8 CBY12148.1 - 2.9 7.9 8.7 0.56 10.2 1.3 2.3 1 1 1 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 EGF_CA PF07645.15 CBY12149.1 - 3.4e-15 56.0 51.8 2.8e-08 33.8 4.3 5.5 3 1 2 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.7 CBY12149.1 - 7.2e-13 48.2 20.9 2.2e-05 24.3 0.3 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY12149.1 - 3.8e-09 36.7 63.8 4.1e-07 30.2 4.6 5.4 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY12149.1 - 0.0057 16.9 2.5 0.0057 16.9 2.5 6.5 4 2 0 5 5 5 2 EGF-like domain EGF_3 PF12947.7 CBY12149.1 - 0.034 14.3 1.5 0.034 14.3 1.5 5.8 5 2 0 5 5 5 0 EGF domain RANK_CRD_2 PF18278.1 CBY12149.1 - 0.044 13.9 0.9 0.044 13.9 0.9 3.7 4 0 0 4 4 4 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 RepA_N PF06970.11 CBY12150.1 - 0.11 12.4 0.1 0.99 9.4 0.0 2.3 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus DUF572 PF04502.13 CBY12150.1 - 0.58 9.7 13.9 1 8.9 13.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) 7tm_1 PF00001.21 CBY12151.1 - 4.5e-15 55.7 14.3 1.2e-13 51.0 14.3 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 CBY12151.1 - 0.0099 15.0 7.6 0.028 13.5 7.6 1.8 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) Voltage_CLC PF00654.20 CBY12151.1 - 0.12 11.5 3.7 0.3 10.3 3.6 1.7 1 1 0 1 1 1 0 Voltage gated chloride channel Orf78 PF06024.12 CBY12151.1 - 0.19 12.0 7.0 2.2 8.6 0.1 2.8 2 1 1 3 3 3 0 Orf78 (ac78) DUF2207 PF09972.9 CBY12151.1 - 0.44 9.2 3.9 0.64 8.7 0.0 2.3 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) Yip1 PF04893.17 CBY12151.1 - 3.5 7.3 10.1 0.14 11.8 2.5 2.2 2 1 0 2 2 2 0 Yip1 domain DUF3671 PF12420.8 CBY12151.1 - 5.7 7.1 11.2 9.2 6.4 4.1 2.7 1 1 1 2 2 2 0 Protein of unknown function Ion_trans PF00520.31 CBY12152.1 - 1.5e-06 27.6 0.1 1.5e-06 27.6 0.1 2.0 3 0 0 3 3 3 1 Ion transport protein PKD_channel PF08016.12 CBY12152.1 - 0.24 10.0 2.3 0.4 9.3 2.3 1.3 1 0 0 1 1 1 0 Polycystin cation channel Herpes_US9 PF06072.11 CBY12152.1 - 0.52 10.2 1.9 1.1 9.1 1.1 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Kelch_6 PF13964.6 CBY12154.1 - 0.001 19.3 3.5 1.6 9.1 0.0 3.8 4 2 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY12154.1 - 0.0024 17.8 0.1 2 8.5 0.0 2.7 2 0 0 2 2 2 2 Kelch motif HRI1 PF16815.5 CBY12154.1 - 0.0037 17.0 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein HRI1 Kelch_1 PF01344.25 CBY12154.1 - 0.0058 16.2 2.8 0.4 10.3 0.0 3.9 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CBY12154.1 - 0.014 15.4 0.4 3.9 7.6 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 CBY12154.1 - 0.23 11.8 2.1 6.8 7.1 0.1 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY12156.1 - 0.054 13.1 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Kelch motif Sulfotransfer_1 PF00685.27 CBY12159.1 - 3.6e-08 33.2 0.1 3.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY12159.1 - 1.9e-05 25.2 0.1 0.00071 20.0 0.1 2.4 2 0 0 2 2 2 1 Sulfotransferase family DUF1932 PF09130.11 CBY12159.1 - 0.16 12.0 0.0 2.4 8.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1932) Sulfotransfer_2 PF03567.14 CBY12161.1 - 4.3e-18 66.1 1.3 6.1e-18 65.6 1.3 1.2 1 0 0 1 1 1 1 Sulfotransferase family Cadherin PF00028.17 CBY12162.1 - 1.2e-67 224.4 1.8 1e-12 48.3 0.1 7.2 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CBY12162.1 - 5.2e-09 35.8 0.0 9.1e-05 22.2 0.0 3.7 3 0 0 3 3 3 2 Cadherin-like Cadherin_3 PF16184.5 CBY12162.1 - 3.5e-07 30.2 8.0 0.24 11.4 0.1 6.4 7 1 0 7 7 7 2 Cadherin-like TMEM119 PF15724.5 CBY12162.1 - 0.047 13.7 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 TMEM119 family DUF5034 PF16437.5 CBY12162.1 - 0.051 13.6 0.3 0.15 12.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5034) MRP_L53 PF10780.9 CBY12162.1 - 0.15 12.2 0.1 0.82 9.9 0.0 2.3 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 Cadherin PF00028.17 CBY12163.1 - 3.7e-69 229.2 0.6 1.3e-12 47.9 0.0 7.2 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 CBY12163.1 - 9e-10 38.3 0.1 1.9e-05 24.4 0.0 3.9 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 CBY12163.1 - 1.8e-06 27.9 5.9 0.65 10.0 0.1 6.2 6 1 0 6 6 6 2 Cadherin-like TMEM119 PF15724.5 CBY12163.1 - 0.051 13.6 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 TMEM119 family MRP_L53 PF10780.9 CBY12163.1 - 0.14 12.4 0.1 0.82 9.9 0.0 2.4 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 Galactosyl_T PF01762.21 CBY12164.1 - 3.6e-10 40.0 0.1 2.3e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase Galactosyl_T PF01762.21 CBY12165.1 - 1.7e-13 50.9 0.3 3e-13 50.1 0.3 1.4 1 0 0 1 1 1 1 Galactosyltransferase FliW PF02623.15 CBY12165.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 FliW protein Phospholip_A2_1 PF00068.19 CBY12167.1 - 5.2e-16 59.1 10.7 1.2e-15 57.9 10.7 1.7 1 1 0 1 1 1 1 Phospholipase A2 C_LFY_FLO PF17538.2 CBY12167.1 - 0.038 13.5 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula S_100 PF01023.19 CBY12168.1 - 2.8e-05 23.7 0.1 4.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain HSNSD PF12062.8 CBY12169.1 - 0.078 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase Trypsin PF00089.26 CBY12170.1 - 1.7e-46 158.8 1.4 2e-46 158.6 1.4 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY12170.1 - 5.9e-09 37.0 0.1 9e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF417 PF04224.12 CBY12171.1 - 0.013 15.1 0.4 0.02 14.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF417 DUF3671 PF12420.8 CBY12171.1 - 0.057 13.5 2.1 0.091 12.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function RCR PF12273.8 CBY12172.1 - 0.034 14.8 0.8 0.059 14.0 0.8 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Phage_holin_2_1 PF04971.12 CBY12172.1 - 0.067 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage P21 holin S Cadherin PF00028.17 CBY12173.1 - 4.4e-28 97.6 9.0 5.3e-10 39.6 0.5 4.6 4 0 0 4 4 4 4 Cadherin domain Cadherin_3 PF16184.5 CBY12173.1 - 2.2e-09 37.3 6.5 0.0027 17.7 0.1 4.2 3 1 1 4 4 4 2 Cadherin-like Cadherin_C PF01049.17 CBY12173.1 - 0.0001 22.6 0.4 0.00029 21.2 0.4 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region TctB PF07331.11 CBY12173.1 - 0.04 14.2 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family IFT43 PF15305.6 CBY12174.1 - 2.8e-05 24.3 0.5 6.3e-05 23.2 0.2 1.6 1 1 1 2 2 2 1 Intraflagellar transport protein 43 DUF4116 PF13475.6 CBY12174.1 - 0.034 13.9 0.8 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Rtt106_N PF18215.1 CBY12174.1 - 0.2 11.4 1.2 2 8.3 1.2 2.1 1 1 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain Trypsin PF00089.26 CBY12175.1 - 4.7e-44 150.8 3.1 8.4e-44 150.0 3.1 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY12175.1 - 0.00025 22.0 0.5 0.00053 20.9 0.5 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kelch_3 PF13415.6 CBY12176.1 - 0.039 14.2 0.4 3.3 8.1 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY12176.1 - 0.051 13.2 1.9 0.18 11.4 0.1 2.8 3 0 0 3 3 3 0 Kelch motif Cyt_b-c1_8 PF10890.8 CBY12176.1 - 0.092 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 BNIP2 PF12496.8 CBY12177.1 - 0.015 15.7 0.7 0.018 15.5 0.7 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Forkhead PF00250.18 CBY12178.1 - 2.1e-28 98.4 1.9 6.4e-28 96.9 1.9 1.8 1 0 0 1 1 1 1 Forkhead domain PhoLip_ATPase_C PF16212.5 CBY12179.1 - 3.9e-56 190.6 27.7 3.9e-56 190.6 27.7 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBY12179.1 - 1.4e-19 69.5 1.6 4.7e-19 67.8 1.6 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBY12179.1 - 4.5e-14 53.2 3.6 4.2e-08 33.7 1.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY12179.1 - 1.4e-09 37.9 0.0 3.6e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBY12179.1 - 6.3e-08 32.3 0.0 6.3e-08 32.3 0.0 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBY12179.1 - 9.6e-05 22.2 0.0 0.00051 19.8 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ThiJ_like PF17124.5 CBY12182.1 - 0.064 12.9 0.7 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 ThiJ/PfpI family-like Homeodomain PF00046.29 CBY12183.1 - 2.9e-16 59.1 2.0 1.1e-15 57.2 2.0 2.0 1 1 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY12183.1 - 0.016 15.1 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain zf-C4 PF00105.18 CBY12184.1 - 7.2e-29 100.1 11.5 7.2e-29 100.1 11.5 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY12184.1 - 1e-13 51.3 9.6 5.9e-13 48.9 9.6 2.1 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 CBY12184.1 - 0.11 12.6 9.8 0.039 14.1 5.9 2.2 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Sugar_tr PF00083.24 CBY12186.1 - 3.3e-11 42.7 11.7 5.8e-11 41.9 11.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY12186.1 - 9e-11 41.3 9.5 1.6e-05 24.0 0.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3382 PF11862.8 CBY12186.1 - 0.038 14.3 0.3 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Ion_trans PF00520.31 CBY12187.1 - 5.7e-06 25.7 6.7 1.2e-05 24.6 6.7 1.6 1 0 0 1 1 1 1 Ion transport protein DUF2198 PF09964.9 CBY12187.1 - 0.017 15.2 2.0 0.043 13.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) MbeB_N PF04837.12 CBY12187.1 - 0.18 12.1 0.3 0.18 12.1 0.3 1.7 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Galactosyl_T PF01762.21 CBY12188.1 - 9.4e-15 54.9 0.2 1.3e-14 54.5 0.2 1.2 1 0 0 1 1 1 1 Galactosyltransferase HNF-1A_C PF04813.12 CBY12188.1 - 0.031 15.0 0.3 0.6 10.9 0.2 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus CH PF00307.31 CBY12189.1 - 3e-15 56.3 0.0 6e-15 55.4 0.0 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Calponin PF00402.18 CBY12189.1 - 3e-14 52.3 4.9 3e-14 52.3 4.9 2.1 3 0 0 3 3 3 1 Calponin family repeat CDC24 PF06395.11 CBY12189.1 - 0.17 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin BTB_2 PF02214.22 CBY12190.1 - 2e-15 56.9 0.1 3.8e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CBY12190.1 - 0.005 17.0 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain AAA_33 PF13671.6 CBY12191.1 - 1.2e-06 28.7 0.0 1.2e-06 28.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain YflT PF11181.8 CBY12191.1 - 0.16 12.5 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 Heat induced stress protein YflT LMBR1 PF04791.16 CBY12192.1 - 4.1e-148 494.5 19.7 6.1e-148 493.9 19.7 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Orthoreo_P10 PF07204.11 CBY12192.1 - 0.2 11.6 1.9 37 4.3 0.0 3.4 2 1 1 3 3 3 0 Orthoreovirus membrane fusion protein p10 RWD PF05773.22 CBY12193.1 - 4.2e-14 52.8 3.4 4.2e-14 52.8 3.4 1.7 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 CBY12193.1 - 1.2e-05 25.7 5.0 4.5e-05 23.9 5.0 2.0 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 IMD PF08397.11 CBY12193.1 - 0.049 13.0 1.3 0.07 12.5 1.3 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Trm112p PF03966.16 CBY12194.1 - 3.3e-14 53.2 0.0 3.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein DUF1002 PF06207.11 CBY12195.1 - 0.0005 19.7 0.3 0.0005 19.7 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1002) IMUP PF15761.5 CBY12195.1 - 0.044 14.5 4.7 0.044 14.5 4.7 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein MutL_C PF08676.11 CBY12195.1 - 0.051 13.3 0.4 0.1 12.4 0.4 1.5 1 1 0 1 1 1 0 MutL C terminal dimerisation domain DEAD PF00270.29 CBY12196.1 - 3.1e-39 134.6 1.2 5.9e-39 133.6 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY12196.1 - 2.1e-32 111.8 0.4 8.1e-32 109.9 0.2 2.1 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY12196.1 - 0.00095 19.2 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBY12196.1 - 0.016 14.6 1.8 0.14 11.5 0.0 2.6 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 CBY12196.1 - 0.028 14.7 0.1 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.25 CBY12196.1 - 0.04 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.6 CBY12196.1 - 0.097 12.9 0.9 1 9.6 0.9 2.5 1 1 0 1 1 1 0 AAA domain LSM PF01423.22 CBY12197.1 - 4.5e-17 61.5 0.1 6.7e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain GRP PF07172.11 CBY12197.1 - 0.098 13.4 26.3 0.15 12.7 26.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family Adeno_E3A PF05248.12 CBY12197.1 - 0.14 12.2 0.0 19 5.4 0.0 2.1 1 1 1 2 2 2 0 Adenovirus E3A RNA_pol_N PF01194.17 CBY12200.1 - 2.6e-34 117.3 0.3 2.9e-34 117.1 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CBY12200.1 - 0.012 15.8 0.2 0.017 15.3 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ank_2 PF12796.7 CBY12202.1 - 9.8e-24 83.8 0.1 1.7e-15 57.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY12202.1 - 1e-16 61.0 0.1 7.8e-11 42.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY12202.1 - 4e-13 48.2 0.1 7.1e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat SH3_9 PF14604.6 CBY12202.1 - 9.7e-13 47.8 0.4 2.1e-12 46.7 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank PF00023.30 CBY12202.1 - 1e-12 47.9 0.1 2.2e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY12202.1 - 1.9e-12 47.1 0.6 7.2e-07 29.4 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 CBY12202.1 - 9.4e-12 44.4 0.6 2e-11 43.3 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY12202.1 - 1.2e-10 40.9 0.0 2.6e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Fib_alpha PF08702.10 CBY12202.1 - 6 7.0 20.6 0.51 10.5 6.0 3.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CSD PF00313.22 CBY12203.1 - 4.4e-21 74.5 0.4 7.7e-21 73.7 0.4 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain KdpC PF02669.15 CBY12203.1 - 0.0046 16.8 0.2 0.041 13.7 0.1 2.0 2 0 0 2 2 2 1 K+-transporting ATPase, c chain OB_RNB PF08206.11 CBY12203.1 - 0.044 13.5 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain Rrn6 PF10214.9 CBY12203.1 - 0.33 9.4 3.7 0.52 8.7 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SET PF00856.28 CBY12204.1 - 1.7e-19 70.8 0.5 1.7e-19 70.8 0.5 2.6 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 CBY12204.1 - 2.8e-10 40.5 15.1 2.8e-10 40.5 15.1 3.5 2 1 0 2 2 2 1 CXC domain PRC2_HTH_1 PF18118.1 CBY12204.1 - 0.00079 20.2 0.0 0.00079 20.2 0.0 2.7 3 0 0 3 3 3 1 Polycomb repressive complex 2 tri-helical domain Myb_DNA-binding PF00249.31 CBY12204.1 - 0.017 15.3 1.0 0.27 11.4 0.0 3.3 4 0 0 4 4 4 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY12204.1 - 0.07 13.4 2.6 9.6 6.5 0.0 3.5 4 0 0 4 4 4 0 Myb-like DNA-binding domain Collagen PF01391.18 CBY12205.1 - 1.9e-21 75.6 69.2 6.1e-09 35.5 34.7 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Ndc80_HEC PF03801.13 CBY12206.1 - 1.2e-17 63.9 0.5 3.7e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 HEC/Ndc80p family GAS PF13851.6 CBY12206.1 - 0.0073 15.7 10.9 0.0073 15.7 10.9 3.5 1 1 3 4 4 4 1 Growth-arrest specific micro-tubule binding zf-C4H2 PF10146.9 CBY12206.1 - 0.0099 16.2 10.6 0.0099 16.2 10.6 3.2 2 1 1 3 3 3 1 Zinc finger-containing protein DUF2452 PF10504.9 CBY12206.1 - 0.1 12.1 6.0 0.023 14.2 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) KIAA1430 PF13879.6 CBY12206.1 - 0.43 11.4 21.7 0.3 11.9 6.6 3.3 3 0 0 3 3 3 0 KIAA1430 homologue BLOC1_2 PF10046.9 CBY12206.1 - 0.9 9.9 14.4 0.19 12.1 0.9 3.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 CBY12206.1 - 2.6 8.7 27.9 5.1 7.8 5.8 4.4 2 1 1 3 3 3 0 Initiation control protein YabA WW PF00397.26 CBY12207.1 - 2.9e-07 30.5 0.3 6.7e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 WW domain ALMT PF11744.8 CBY12207.1 - 1.3 7.7 12.7 0.026 13.4 2.5 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter SYF2 PF08231.12 CBY12208.1 - 1.4e-42 145.8 16.1 1.4e-42 145.8 16.1 1.7 2 0 0 2 2 2 1 SYF2 splicing factor Sec20 PF03908.13 CBY12209.1 - 0.0036 17.2 0.1 0.0051 16.7 0.1 1.2 1 0 0 1 1 1 1 Sec20 DUF3274 PF11678.8 CBY12209.1 - 0.061 12.6 0.1 0.074 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) DUF501 PF04417.12 CBY12209.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) N2227 PF07942.12 CBY12210.1 - 3.9e-76 255.8 0.0 4.4e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 CBY12210.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBY12210.1 - 0.012 16.3 0.0 0.15 12.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CBY12210.1 - 0.02 15.5 0.0 0.28 11.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CBY12210.1 - 0.19 12.5 0.0 3.7 8.3 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain ATP_synt_H PF05493.13 CBY12211.1 - 1.7e-18 66.8 8.2 2e-18 66.6 8.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit H SPATA48 PF15073.6 CBY12212.1 - 0.04 14.2 0.1 0.046 14.0 0.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 PfkB PF00294.24 CBY12213.1 - 9.4e-51 172.9 0.7 1.2e-50 172.6 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CBY12213.1 - 3.9e-05 23.2 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF5518 PF17647.1 CBY12213.1 - 0.049 13.8 0.3 0.085 13.0 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5518) NPBW PF15180.6 CBY12215.1 - 0.11 12.4 0.1 0.36 10.7 0.1 1.9 1 0 0 1 1 1 0 Neuropeptides B and W Fam20C PF06702.12 CBY12216.1 - 9.1e-82 274.1 0.2 1.6e-81 273.3 0.2 1.4 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 SUKH_5 PF14567.6 CBY12216.1 - 0.0097 15.6 0.3 0.028 14.2 0.3 1.8 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall Ank_4 PF13637.6 CBY12217.1 - 1.4e-22 79.8 1.2 9e-10 38.9 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY12217.1 - 3.4e-15 56.4 0.1 8e-14 52.0 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY12217.1 - 8.6e-15 54.4 0.0 2.1e-07 31.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY12217.1 - 9.1e-14 51.4 1.0 3.5e-07 30.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY12217.1 - 2.7e-13 48.8 0.0 5.6e-05 23.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat ACBP PF00887.19 CBY12218.1 - 7.7e-19 67.7 0.3 1.3e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.32 CBY12219.1 - 8.1e-46 153.1 32.5 1.9e-07 31.6 0.2 10.3 10 0 0 10 10 10 8 WD domain, G-beta repeat Utp13 PF08625.11 CBY12219.1 - 5.8e-25 87.9 0.2 1.2e-24 86.9 0.2 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CBY12219.1 - 1.9e-22 79.4 4.8 8.4e-06 26.0 0.1 7.0 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY12219.1 - 1.4e-08 34.5 2.7 0.0091 15.3 0.0 4.3 4 1 1 5 5 5 3 WD40-like domain eIF2A PF08662.11 CBY12219.1 - 0.00018 21.4 0.0 0.095 12.6 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CBY12219.1 - 0.00091 18.0 3.6 5.1 5.6 0.0 5.0 5 1 1 6 6 6 2 Nucleoporin Nup120/160 Peptidase_M13 PF01431.21 CBY12219.1 - 0.05 13.2 0.4 0.1 12.2 0.4 1.4 1 0 0 1 1 1 0 Peptidase family M13 MCM_lid PF17855.1 CBY12219.1 - 0.083 13.3 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 MCM AAA-lid domain DUF2073 PF09846.9 CBY12219.1 - 0.093 12.6 0.3 0.24 11.3 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) Methuselah_N PF06652.12 CBY12219.1 - 0.29 11.0 1.6 0.71 9.8 0.9 1.9 2 0 0 2 2 2 0 Methuselah N-terminus HS1_rep PF02218.15 CBY12220.1 - 1e-52 176.1 46.5 1.6e-20 73.1 3.7 5.9 6 0 0 6 6 6 4 Repeat in HS1/Cortactin SH3_9 PF14604.6 CBY12220.1 - 2.1e-15 56.3 0.1 4.9e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY12220.1 - 3.3e-14 52.2 0.3 3.3e-14 52.2 0.3 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CBY12220.1 - 4e-09 36.0 0.0 8.7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain OMP_b-brl PF13505.6 CBY12220.1 - 4.9 7.2 8.4 2e+02 2.0 8.4 2.5 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain PAPS_reduct PF01507.19 CBY12221.1 - 2.6 8.0 6.5 4 7.5 6.5 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family M16C_assoc PF08367.11 CBY12221.1 - 4.5 6.3 10.3 7.2 5.7 10.3 1.3 1 0 0 1 1 1 0 Peptidase M16C associated ER PF01133.17 CBY12222.1 - 4.4e-41 138.9 0.2 4.9e-41 138.7 0.2 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary HSR PF03172.13 CBY12222.1 - 0.027 14.6 0.3 0.039 14.1 0.3 1.2 1 0 0 1 1 1 0 HSR domain DUF4735 PF15882.5 CBY12222.1 - 0.091 12.2 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) Aa_trans PF01490.18 CBY12223.1 - 1.3e-56 192.1 32.5 1.6e-56 191.8 32.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5537 PF17690.1 CBY12225.1 - 0.0002 21.1 1.3 0.00041 20.1 1.3 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5537) Exonuc_X-T_C PF08411.10 CBY12225.1 - 0.0026 16.9 0.4 0.0045 16.2 0.4 1.5 1 0 0 1 1 1 1 Exonuclease C-terminal Iwr1 PF08574.10 CBY12227.1 - 2.9e-09 37.8 17.8 2.9e-09 37.8 17.8 2.6 2 0 0 2 2 2 1 Transcription factor Iwr1 TPR_2 PF07719.17 CBY12228.1 - 6.8e-09 35.2 0.1 4.8e-05 23.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY12228.1 - 1.4e-06 27.9 0.2 0.0003 20.5 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY12228.1 - 2.9e-05 24.3 0.0 0.31 11.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY12228.1 - 0.0001 22.7 0.2 0.004 17.7 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY12228.1 - 0.00013 21.6 0.0 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 CBY12228.1 - 0.00023 21.8 0.0 0.051 14.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY12228.1 - 0.0023 18.4 0.0 0.017 15.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBY12228.1 - 0.0082 16.1 0.8 0.19 11.7 0.0 2.6 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Allexi_40kDa PF05549.11 CBY12228.1 - 0.016 14.7 0.4 0.016 14.7 0.4 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein TPR_14 PF13428.6 CBY12228.1 - 0.02 15.7 0.0 0.35 11.8 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY12228.1 - 0.024 14.9 0.1 0.1 12.8 0.1 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CBY12228.1 - 0.076 13.3 4.4 0.095 13.0 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat LMBR1 PF04791.16 CBY12228.1 - 1.5 7.6 12.3 0.22 10.4 1.4 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein MMS19_N PF14500.6 CBY12229.1 - 0.081 12.5 0.2 0.19 11.3 0.1 1.6 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HECT PF00632.25 CBY12230.1 - 1.4e-74 251.4 0.0 2.1e-74 250.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 CBY12230.1 - 3.3e-74 245.3 17.3 2.8e-12 47.0 0.3 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY12230.1 - 4.4e-45 150.6 33.3 1.9e-10 40.2 0.9 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat CdiA_C PF18451.1 CBY12230.1 - 0.24 11.6 0.7 0.99 9.7 0.3 2.2 1 1 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain PIRT PF15099.6 CBY12231.1 - 0.00021 20.8 0.8 0.00049 19.7 0.8 1.7 1 1 0 1 1 1 1 Phosphoinositide-interacting protein family PTS_EIIC_2 PF13303.6 CBY12231.1 - 0.046 12.7 0.1 0.058 12.4 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF3481 PF11980.8 CBY12231.1 - 0.067 12.9 0.4 0.11 12.2 0.3 1.4 1 1 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein EphA2_TM PF14575.6 CBY12231.1 - 0.068 14.0 0.0 0.11 13.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.6 CBY12233.1 - 0.0015 19.0 0.2 0.082 13.4 0.0 2.2 2 0 0 2 2 2 1 SCIMP protein LapA_dom PF06305.11 CBY12233.1 - 0.0043 16.8 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain EVC2_like PF12297.8 CBY12233.1 - 0.0087 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein TPK_catalytic PF04263.16 CBY12234.1 - 7.9e-29 100.2 0.0 1.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CBY12234.1 - 1.5e-13 50.2 0.0 2.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Gelsolin PF00626.22 CBY12235.1 - 1.1e-44 150.3 0.1 4.9e-15 55.2 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat AAA_6 PF12774.7 CBY12236.1 - 2e-119 398.4 0.0 9.6e-119 396.2 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 CBY12236.1 - 2.6e-60 204.3 0.0 6.1e-60 203.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CBY12236.1 - 1.5e-32 112.7 0.3 5.7e-32 110.8 0.3 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain DHC_N2 PF08393.13 CBY12236.1 - 3.1e-24 85.8 0.1 3.1e-24 85.8 0.1 3.5 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CBY12236.1 - 1e-14 54.7 0.1 6.6e-08 32.6 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY12236.1 - 5.8e-12 45.5 0.6 0.00035 20.1 0.0 3.7 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_18 PF13238.6 CBY12236.1 - 2.2e-10 41.2 0.8 0.00025 21.6 0.1 3.3 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 CBY12236.1 - 4.1e-07 30.5 5.9 0.0012 19.2 0.0 4.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CBY12236.1 - 3.3e-05 24.1 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CBY12236.1 - 5.7e-05 23.4 0.9 0.08 13.2 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 CBY12236.1 - 0.00018 21.9 0.5 0.34 11.3 0.0 3.2 3 0 0 3 3 2 1 AAA ATPase domain AAA_30 PF13604.6 CBY12236.1 - 0.00025 20.8 0.1 0.58 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CBY12236.1 - 0.00026 21.3 0.1 1.4 9.3 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CBY12236.1 - 0.0015 18.8 0.1 2.6 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CBY12236.1 - 0.0016 18.2 5.2 0.0052 16.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 CBY12236.1 - 0.0017 18.8 0.1 0.008 16.7 0.1 2.1 1 0 0 1 1 1 1 ABC transporter TsaE PF02367.17 CBY12236.1 - 0.0034 17.4 0.4 0.97 9.4 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CBY12236.1 - 0.0086 15.5 0.2 0.065 12.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Septin PF00735.18 CBY12236.1 - 0.012 14.9 0.6 0.17 11.1 0.2 2.4 2 0 0 2 2 2 0 Septin Rad17 PF03215.15 CBY12236.1 - 0.021 14.8 0.1 0.88 9.5 0.0 2.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_19 PF13245.6 CBY12236.1 - 0.028 14.8 0.6 2.5 8.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 CBY12236.1 - 0.04 12.5 0.7 1.5 7.3 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) CbiA PF01656.23 CBY12236.1 - 0.065 13.3 2.2 1.7 8.7 0.7 3.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 CBY12236.1 - 0.072 12.8 0.6 0.91 9.2 0.1 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.9 CBY12236.1 - 0.083 12.6 0.1 0.29 10.9 0.1 2.0 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 CBY12236.1 - 0.13 12.2 0.6 5 7.0 0.2 2.9 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 CBY12236.1 - 0.13 12.0 0.3 0.39 10.5 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 CBY12236.1 - 0.13 11.9 0.2 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 CBY12236.1 - 0.2 10.9 0.3 21 4.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 CBY12236.1 - 0.24 10.7 0.7 0.47 9.8 0.1 1.8 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 CBY12236.1 - 7.6 7.0 15.7 7.7 7.0 9.2 3.8 2 1 0 2 2 2 0 AAA domain Glyco_hydro_9 PF00759.19 CBY12237.1 - 2.6e-54 185.2 3.7 3.7e-54 184.7 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 EGF PF00008.27 CBY12237.1 - 0.00087 19.5 8.4 0.0022 18.3 8.4 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 CBY12237.1 - 0.049 14.0 10.3 0.12 12.8 10.3 1.6 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 CBY12237.1 - 0.098 12.8 4.2 0.23 11.7 4.2 1.5 1 0 0 1 1 1 0 Laminin EGF domain Plasmod_Pvs28 PF06247.11 CBY12237.1 - 0.38 11.1 4.8 1.4 9.3 4.8 1.9 1 1 0 1 1 1 0 Pvs28 EGF domain hEGF PF12661.7 CBY12237.1 - 1.1 10.0 5.2 3.1 8.6 5.2 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF Kelch_5 PF13854.6 CBY12239.1 - 0.007 16.3 1.1 0.1 12.6 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY12239.1 - 0.013 15.8 0.9 2.7 8.4 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 CBY12239.1 - 0.035 14.1 0.7 2.6 8.2 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Cortex-I_coil PF09304.10 CBY12239.1 - 7.4 6.8 13.8 1.3 9.3 8.2 2.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil EGF_CA PF07645.15 CBY12240.1 - 7.1e-32 109.3 78.1 2e-07 31.1 8.0 5.6 5 0 0 5 5 5 5 Calcium-binding EGF domain PKD_channel PF08016.12 CBY12240.1 - 1.6e-17 63.3 18.0 1.6e-17 63.3 18.0 2.8 3 0 0 3 3 3 1 Polycystin cation channel hEGF PF12661.7 CBY12240.1 - 1.4e-11 44.5 44.0 0.011 16.3 3.2 6.6 5 0 0 5 5 5 5 Human growth factor-like EGF cEGF PF12662.7 CBY12240.1 - 2.3e-11 43.4 43.2 0.00085 19.2 1.2 5.3 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY12240.1 - 5.5e-08 32.9 71.7 0.00042 20.4 6.3 6.5 5 2 0 6 6 6 4 EGF domain EGF PF00008.27 CBY12240.1 - 6.3e-07 29.6 67.4 0.0016 18.7 5.9 6.7 4 1 1 6 6 6 4 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY12240.1 - 0.0006 20.1 7.8 0.0006 20.1 7.8 5.9 6 0 0 6 6 6 3 Pvs28 EGF domain FXa_inhibition PF14670.6 CBY12240.1 - 0.01 16.1 74.3 0.038 14.3 6.8 6.3 4 1 2 6 6 6 0 Coagulation Factor Xa inhibitory site TIP49_C PF17856.1 CBY12240.1 - 0.093 12.9 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 TIP49 AAA-lid domain EGF_MSP1_1 PF12946.7 CBY12240.1 - 0.44 10.6 59.1 0.018 15.1 4.2 5.4 5 0 0 5 5 5 0 MSP1 EGF domain 1 Kelch_6 PF13964.6 CBY12241.1 - 2.4e-11 43.5 3.5 0.0024 18.1 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CBY12241.1 - 9.2e-10 38.1 1.4 0.00095 19.1 0.1 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CBY12241.1 - 7e-05 22.7 5.3 0.14 12.2 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY12241.1 - 0.001 18.6 2.2 1.2 8.8 0.2 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY12241.1 - 0.0042 17.0 10.3 0.018 15.0 0.2 3.4 4 0 0 4 4 4 2 Kelch motif PucR PF07905.11 CBY12243.1 - 0.18 12.1 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family PLAC8 PF04749.17 CBY12244.1 - 1.3e-17 64.6 11.5 2e-17 64.0 11.5 1.2 1 0 0 1 1 1 1 PLAC8 family EGF_CA PF07645.15 CBY12246.1 - 3.4e-06 27.2 8.0 3.4e-06 27.2 8.0 6.4 4 2 1 6 6 6 2 Calcium-binding EGF domain EGF_3 PF12947.7 CBY12246.1 - 0.00012 22.2 26.3 0.00016 21.8 5.4 4.8 3 1 0 3 3 3 2 EGF domain cEGF PF12662.7 CBY12246.1 - 0.0058 16.5 4.8 0.0058 16.5 4.8 6.5 6 1 0 6 6 6 1 Complement Clr-like EGF-like Kelch_2 PF07646.15 CBY12247.1 - 0.0046 16.9 0.6 9 6.5 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY12247.1 - 0.0054 16.7 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 CBY12247.1 - 0.16 12.3 0.2 14 6.2 0.0 3.6 3 0 0 3 3 3 0 Kelch motif Lectin_C PF00059.21 CBY12248.1 - 2.4e-14 53.9 9.7 2.3e-12 47.6 0.2 2.9 2 1 0 2 2 2 2 Lectin C-type domain HAUS-augmin3 PF14932.6 CBY12249.1 - 0.0092 15.6 1.9 0.014 15.0 1.9 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Kelch_2 PF07646.15 CBY12249.1 - 0.024 14.6 0.4 1.3 9.1 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Lectin_N PF03954.14 CBY12249.1 - 0.025 14.3 2.5 0.041 13.6 2.5 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Seryl_tRNA_N PF02403.22 CBY12249.1 - 0.067 13.4 7.7 0.14 12.4 7.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 CBY12249.1 - 0.084 12.9 0.7 0.14 12.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4446 PF14584.6 CBY12249.1 - 0.12 12.4 0.6 0.18 11.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) HIP1_clath_bdg PF16515.5 CBY12249.1 - 0.16 12.6 3.5 0.3 11.7 3.5 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 CBY12249.1 - 0.19 11.8 8.3 0.35 10.9 8.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 CBY12249.1 - 0.21 10.9 0.9 0.35 10.2 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 CBY12249.1 - 0.23 11.9 10.0 0.37 11.2 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CHD5 PF04420.14 CBY12249.1 - 0.32 10.9 3.6 0.53 10.1 3.6 1.2 1 0 0 1 1 1 0 CHD5-like protein HALZ PF02183.18 CBY12249.1 - 0.35 11.1 11.2 0.82 9.9 3.5 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fungal_TACC PF12709.7 CBY12249.1 - 1 9.8 8.2 0.49 10.9 4.1 2.5 2 1 1 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins ZapB PF06005.12 CBY12249.1 - 2.7 8.5 11.9 11 6.5 11.9 2.0 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 CBY12249.1 - 5.4 7.7 6.4 79 4.0 1.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Kelch_2 PF07646.15 CBY12250.1 - 8.8e-06 25.5 0.3 33 4.7 0.0 5.4 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 CBY12250.1 - 6.3e-05 22.9 0.2 6.3 6.9 0.0 4.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY12250.1 - 0.0011 19.2 4.1 4 7.9 0.0 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_5 PF13854.6 CBY12250.1 - 0.014 15.3 2.9 1.1 9.3 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Peptidase_S32 PF05579.13 CBY12250.1 - 0.023 13.9 0.0 4.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 OAM_dimer PF16554.5 CBY12250.1 - 0.076 13.5 0.0 7.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Phage_NinH PF06322.11 CBY12250.1 - 0.19 11.7 0.2 29 4.7 0.0 2.5 2 0 0 2 2 2 0 Phage NinH protein Rad50_zn_hook PF04423.14 CBY12251.1 - 0.024 14.5 0.1 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 CBY12251.1 - 0.027 14.7 0.2 0.031 14.6 0.2 1.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Vps39_2 PF10367.9 CBY12251.1 - 0.057 13.9 0.1 0.057 13.9 0.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 CBY12252.1 - 3.2e-06 27.0 3.4 6e-06 26.2 3.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY12252.1 - 2.5e-05 24.5 7.1 3.9e-05 23.9 7.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY12252.1 - 0.00068 19.5 9.9 0.0035 17.2 10.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY12252.1 - 0.00084 19.1 10.3 0.0035 17.1 10.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY12252.1 - 0.0011 18.9 9.2 0.0032 17.4 9.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_5 PF17121.5 CBY12252.1 - 0.0017 18.2 6.1 0.0033 17.3 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY12252.1 - 0.0032 17.3 10.6 0.0094 15.8 10.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 CBY12252.1 - 0.032 14.5 6.3 0.063 13.5 6.3 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain HMMR_N PF15905.5 CBY12252.1 - 0.037 13.5 13.4 0.065 12.7 13.4 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Macoilin PF09726.9 CBY12252.1 - 0.057 12.0 10.9 0.079 11.5 10.9 1.2 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 CBY12252.1 - 0.064 12.1 14.6 0.13 11.1 14.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_4 PF14570.6 CBY12252.1 - 0.073 12.9 6.3 0.15 11.9 6.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CBY12252.1 - 0.18 12.0 6.8 1.1 9.4 6.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF812 PF05667.11 CBY12252.1 - 0.26 10.1 18.8 0.64 8.8 18.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Prok-RING_4 PF14447.6 CBY12252.1 - 0.27 11.2 11.7 0.078 12.8 4.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CBY12252.1 - 1.8 8.3 10.9 3.4 7.5 10.9 1.5 1 0 0 1 1 1 0 RING-like zinc finger DUF1664 PF07889.12 CBY12252.1 - 3.2 7.8 9.3 8.5 6.4 7.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 CBY12252.1 - 3.2 5.5 6.9 3.7 5.3 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.11 CBY12252.1 - 4.7 6.7 11.1 8.2 6.0 10.8 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fzo_mitofusin PF04799.13 CBY12252.1 - 7 6.2 9.8 7.7 6.0 5.5 2.1 1 1 1 2 2 2 0 fzo-like conserved region UPF0242 PF06785.11 CBY12253.1 - 3.8e-06 27.2 1.7 6.1e-06 26.5 1.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Kelch_5 PF13854.6 CBY12253.1 - 0.0011 18.9 1.9 0.37 10.8 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY12253.1 - 0.025 14.9 0.9 0.84 10.0 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Hema_stalk PF08720.10 CBY12253.1 - 0.031 14.0 0.9 0.2 11.3 0.0 2.3 2 1 1 3 3 3 0 Influenza C hemagglutinin stalk Leu_zip PF15294.6 CBY12253.1 - 0.035 13.6 2.7 0.056 13.0 2.7 1.2 1 0 0 1 1 1 0 Leucine zipper SHE3 PF17078.5 CBY12253.1 - 0.047 13.4 6.8 0.093 12.4 6.8 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Spc42p PF11544.8 CBY12253.1 - 0.063 13.3 2.4 0.14 12.2 2.4 1.5 1 0 0 1 1 1 0 Spindle pole body component Spc42p DUF2681 PF10883.8 CBY12253.1 - 0.085 13.3 0.2 0.73 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Kelch_2 PF07646.15 CBY12253.1 - 0.13 12.3 0.7 1.3 9.2 0.0 2.8 3 0 0 3 3 2 0 Kelch motif ZapB PF06005.12 CBY12253.1 - 0.13 12.7 7.2 0.51 10.8 1.5 2.3 2 0 0 2 2 2 0 Cell division protein ZapB ATG16 PF08614.11 CBY12253.1 - 0.18 12.0 6.5 0.32 11.2 6.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Kelch_4 PF13418.6 CBY12253.1 - 0.22 11.5 1.1 9.7 6.3 0.0 3.1 2 1 0 2 2 2 0 Galactose oxidase, central domain YabA PF06156.13 CBY12253.1 - 0.24 12.0 6.9 4.2 8.1 1.9 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 CBY12253.1 - 1.3 9.2 10.9 0.95 9.6 4.7 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 SIKE PF05769.11 CBY12253.1 - 7.8 6.4 8.6 18 5.2 3.2 2.3 1 1 1 2 2 2 0 SIKE family UPF0242 PF06785.11 CBY12254.1 - 2.4e-06 27.8 1.9 4.2e-06 27.0 1.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Kelch_5 PF13854.6 CBY12254.1 - 4.5e-05 23.3 0.5 0.003 17.5 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY12254.1 - 0.003 17.8 2.9 0.77 10.1 0.0 4.2 4 2 1 5 5 5 1 Kelch motif Leu_zip PF15294.6 CBY12254.1 - 0.0063 16.1 2.2 0.0096 15.5 2.2 1.2 1 0 0 1 1 1 1 Leucine zipper Kelch_4 PF13418.6 CBY12254.1 - 0.028 14.4 0.4 7.2 6.7 0.2 2.9 2 1 0 2 2 2 0 Galactose oxidase, central domain SHE3 PF17078.5 CBY12254.1 - 0.041 13.6 7.4 0.079 12.7 7.0 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 CBY12254.1 - 0.049 13.8 7.8 0.082 13.1 7.8 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 CBY12254.1 - 0.097 13.3 8.0 1.7 9.3 2.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF2681 PF10883.8 CBY12254.1 - 0.11 13.0 2.6 0.44 11.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) APC_N_CC PF16689.5 CBY12254.1 - 0.15 12.1 0.9 0.45 10.6 0.1 2.1 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain ZapB PF06005.12 CBY12254.1 - 0.58 10.6 10.4 1 9.8 2.4 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 CBY12254.1 - 8.9 6.5 11.9 4.7 7.4 4.1 2.3 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Herpes_LMP1 PF05297.11 CBY12255.1 - 5 6.2 5.2 6.9 5.8 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Peptidase_M14 PF00246.24 CBY12257.1 - 5.3e-75 252.9 0.0 7.1e-75 252.5 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase SelP_N PF04592.14 CBY12259.1 - 0.42 10.0 13.7 0.56 9.6 13.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TSP_1 PF00090.19 CBY12260.1 - 7.6e-08 32.5 11.4 7.6e-08 32.5 11.4 3.2 2 1 0 2 2 2 1 Thrombospondin type 1 domain YebO PF13974.6 CBY12261.1 - 0.076 13.1 0.1 0.25 11.4 0.1 1.9 1 0 0 1 1 1 0 YebO-like protein SOGA PF11365.8 CBY12262.1 - 0.00084 20.4 2.1 0.00084 20.4 2.1 3.2 1 1 2 3 3 3 1 Protein SOGA DUF2576 PF10845.8 CBY12262.1 - 0.015 14.9 0.2 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) PRKG1_interact PF15898.5 CBY12262.1 - 0.046 14.6 16.8 0.072 14.0 7.9 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TSC22 PF01166.18 CBY12262.1 - 0.059 13.7 11.1 6.5 7.2 0.2 4.0 3 2 1 4 4 4 0 TSC-22/dip/bun family BSD PF03909.17 CBY12262.1 - 0.073 13.1 0.8 3.6 7.7 0.1 3.3 1 1 2 3 3 3 0 BSD domain GAS PF13851.6 CBY12262.1 - 0.084 12.2 21.1 0.077 12.3 11.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding KIAA1430 PF13879.6 CBY12262.1 - 0.19 12.5 12.7 0.39 11.5 3.7 2.5 1 1 1 2 2 2 0 KIAA1430 homologue DivIC PF04977.15 CBY12262.1 - 0.43 10.4 15.5 2.4 8.0 1.1 4.0 2 1 2 4 4 4 0 Septum formation initiator Fez1 PF06818.15 CBY12262.1 - 1.5 9.2 13.9 4.3 7.7 13.9 1.7 1 1 0 1 1 1 0 Fez1 Striatin PF08232.12 CBY12262.1 - 2.1 8.9 12.7 1.5 9.4 10.3 1.9 1 1 0 2 2 2 0 Striatin family YlqD PF11068.8 CBY12262.1 - 2.5 8.5 6.2 2.1 8.7 0.3 2.4 1 1 0 2 2 2 0 YlqD protein Sas10_Utp3 PF04000.15 CBY12262.1 - 7.8 7.2 11.2 0.34 11.5 2.1 2.7 2 1 0 2 2 2 0 Sas10/Utp3/C1D family bZIP_2 PF07716.15 CBY12262.1 - 8.2 6.6 15.6 13 6.0 0.9 4.1 4 0 0 4 4 4 0 Basic region leucine zipper ZapB PF06005.12 CBY12262.1 - 8.3 6.9 20.7 0.55 10.7 2.4 3.2 3 0 0 3 3 3 0 Cell division protein ZapB DUF4140 PF13600.6 CBY12262.1 - 8.8 6.8 11.2 2.7 8.5 1.0 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Ank_2 PF12796.7 CBY12263.1 - 6.2e-14 52.4 1.9 6e-11 42.8 0.6 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY12263.1 - 1.5e-09 37.2 0.1 0.028 15.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CBY12263.1 - 4.8e-09 36.6 0.3 3.9e-08 33.7 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY12263.1 - 3.1e-08 33.7 0.2 0.00043 20.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Fez1 PF06818.15 CBY12263.1 - 5.6e-06 27.0 9.3 1.1e-05 26.0 9.3 1.4 1 0 0 1 1 1 1 Fez1 Ank PF00023.30 CBY12263.1 - 1.5e-05 25.2 0.1 0.028 14.9 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat ADIP PF11559.8 CBY12263.1 - 0.01 15.9 6.9 0.025 14.7 0.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4686 PF15742.5 CBY12263.1 - 0.015 14.5 12.4 0.026 13.7 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) FAM76 PF16046.5 CBY12263.1 - 0.039 13.3 10.2 0.18 11.1 10.2 1.9 1 1 0 1 1 1 0 FAM76 protein HIP1_clath_bdg PF16515.5 CBY12263.1 - 0.17 12.5 12.4 0.31 11.7 4.5 3.3 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DHR10 PF18595.1 CBY12263.1 - 0.18 11.9 14.9 0.12 12.4 6.0 2.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Erp_C PF06780.11 CBY12263.1 - 0.22 11.5 5.5 0.62 10.1 5.5 1.8 1 0 0 1 1 1 0 Erp protein C-terminus UPF0242 PF06785.11 CBY12263.1 - 0.23 11.6 11.1 0.39 10.8 11.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 CBY12263.1 - 0.3 9.9 12.2 0.5 9.2 12.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 CBY12263.1 - 0.53 9.7 14.8 1.3 8.5 14.8 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 Cep57_MT_bd PF06657.13 CBY12263.1 - 0.63 10.5 10.2 1.1 9.7 3.2 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 CC2-LZ PF16516.5 CBY12263.1 - 0.65 10.4 11.3 1.6 9.2 11.3 1.7 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TMPIT PF07851.13 CBY12263.1 - 0.85 8.8 4.2 1.2 8.3 4.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 CBY12263.1 - 1.3 9.7 5.0 0.96 10.1 1.1 2.5 1 1 0 2 2 2 0 SlyX NYD-SP28 PF14772.6 CBY12263.1 - 2.5 8.2 15.7 0.34 11.0 8.2 2.5 1 1 1 2 2 2 0 Sperm tail NPV_P10 PF05531.12 CBY12263.1 - 2.8 8.5 6.5 3.5 8.1 1.6 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 CBY12263.1 - 4.2 7.9 10.0 6.6 7.3 5.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 CBY12263.1 - 4.2 7.4 6.1 17 5.4 5.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CBY12263.1 - 5.7 6.8 12.5 0.76 9.6 1.8 3.0 2 1 0 3 3 3 0 Septum formation initiator ERM PF00769.19 CBY12263.1 - 7.8 6.2 18.5 2 8.1 14.5 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-Q PF13094.6 CBY12263.1 - 8.7 6.5 18.3 2 8.6 7.6 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase PF00069.25 CBY12264.1 - 9e-61 205.5 0.0 1.1e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12264.1 - 9.7e-39 133.2 0.0 1.2e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY12264.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY12264.1 - 2.2e-05 23.6 0.1 3.4e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBY12264.1 - 0.00044 19.7 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY12264.1 - 0.018 14.6 0.2 0.03 13.9 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CBY12264.1 - 0.19 11.6 0.1 0.9 9.4 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family PGI PF00342.19 CBY12265.1 - 8.1e-206 684.3 7.7 7.8e-120 400.7 0.3 2.0 1 1 1 2 2 2 2 Phosphoglucose isomerase RasGEF PF00617.19 CBY12266.1 - 4e-45 154.2 0.1 7.6e-45 153.3 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CBY12266.1 - 2.2e-19 69.7 0.4 8.6e-19 67.7 0.4 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 CBY12266.1 - 1.2e-09 38.7 0.0 3.2e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Glyco_hydro38C2 PF17677.1 CBY12266.1 - 0.024 14.7 0.4 0.12 12.5 0.3 2.4 2 1 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain MgtE PF01769.16 CBY12267.1 - 9.2e-46 155.3 28.9 9.4e-25 87.4 4.0 2.8 4 0 0 4 4 4 2 Divalent cation transporter ARD PF03079.14 CBY12268.1 - 1.7e-43 148.6 0.2 2e-43 148.3 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CBY12268.1 - 4.1e-07 29.6 0.0 7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CBY12268.1 - 0.00091 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CBY12268.1 - 0.044 13.4 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.6 CBY12268.1 - 0.049 13.3 0.0 0.087 12.5 0.0 1.6 1 1 0 1 1 1 0 Cupin-like domain Xlink PF00193.17 CBY12273.1 - 0.16 12.4 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Extracellular link domain DUF5349 PF17298.2 CBY12274.1 - 5 6.8 8.0 7.4 6.2 8.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Spectrin PF00435.21 CBY12275.1 - 1.6e-60 202.1 19.2 3.4e-22 78.9 5.1 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 CBY12275.1 - 1.5e-49 166.7 0.3 7.8e-25 87.2 0.0 3.7 4 0 0 4 4 4 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 CBY12275.1 - 4.2e-26 90.8 0.2 3.1e-25 88.0 0.0 2.7 3 0 0 3 3 3 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 CBY12275.1 - 1.3e-07 30.6 0.1 0.0095 15.4 0.0 3.2 3 0 0 3 3 2 2 EF hand CAMSAP_CH PF11971.8 CBY12275.1 - 5.1e-07 29.4 0.1 1.7e-06 27.7 0.1 2.0 1 0 0 1 1 1 1 CAMSAP CH domain EF-hand_7 PF13499.6 CBY12275.1 - 6.6e-07 29.7 0.6 3.2e-06 27.5 0.0 2.6 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY12275.1 - 2e-05 24.2 0.2 0.015 15.2 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBY12275.1 - 2.4e-05 24.1 0.1 0.0015 18.4 0.0 2.9 1 1 1 2 2 2 2 EF-hand domain pair Terminase_4 PF05119.12 CBY12275.1 - 0.055 13.9 0.1 0.28 11.6 0.1 2.3 1 0 0 1 1 1 0 Phage terminase, small subunit Noelin-1 PF12308.8 CBY12275.1 - 0.24 11.4 2.6 11 6.0 0.1 3.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein DUF2284 PF10050.9 CBY12275.1 - 2 8.2 3.7 8.3 6.1 0.2 2.6 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) DUF349 PF03993.12 CBY12275.1 - 3.7 7.9 12.3 0.17 12.2 0.3 4.5 4 1 1 5 5 5 0 Domain of Unknown Function (DUF349) PDZ PF00595.24 CBY12277.1 - 8.9e-13 48.4 0.7 1.9e-12 47.4 0.7 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY12277.1 - 0.0011 18.8 0.1 0.0027 17.5 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY12277.1 - 0.065 13.6 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Methyltransf_15 PF09445.10 CBY12277.1 - 0.11 12.0 0.1 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase DUF4472 PF14739.6 CBY12277.1 - 2.8 8.7 11.7 1.5 9.6 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) CENP-H PF05837.12 CBY12277.1 - 3.3 8.2 11.9 2.6 8.5 5.6 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) KASH_CCD PF14662.6 CBY12277.1 - 3.3 7.5 16.9 13 5.6 16.9 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH zf-RING_2 PF13639.6 CBY12278.1 - 2.4e-08 34.2 7.7 2.4e-08 34.2 7.7 2.5 2 1 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CBY12278.1 - 0.00081 19.1 8.9 0.0018 18.0 8.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 CBY12278.1 - 0.00084 18.9 6.0 0.00084 18.9 6.0 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CBY12278.1 - 0.003 17.4 7.9 0.003 17.4 7.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY12278.1 - 0.01 16.1 14.5 0.018 15.3 8.2 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain RNF220 PF15926.5 CBY12278.1 - 0.012 15.2 0.7 0.015 14.9 0.7 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 FANCL_C PF11793.8 CBY12278.1 - 0.027 14.6 10.6 0.052 13.7 7.5 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 CBY12278.1 - 0.065 13.6 10.1 0.085 13.2 5.1 2.3 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.7 CBY12278.1 - 0.95 9.6 9.7 0.3 11.3 6.0 2.1 2 1 0 2 2 2 0 RING-variant domain zf-RING_UBOX PF13445.6 CBY12278.1 - 6.2 6.9 15.9 0.079 13.0 7.7 2.0 2 1 0 2 2 2 0 RING-type zinc-finger AGTRAP PF06396.11 CBY12279.1 - 2e-21 76.3 0.1 2.3e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Methyltransf_31 PF13847.6 CBY12280.1 - 6.2e-23 81.3 0.0 9.1e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY12280.1 - 9.2e-23 80.9 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY12280.1 - 7.4e-21 74.7 0.0 1.9e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY12280.1 - 3.1e-20 72.6 0.0 6.8e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY12280.1 - 5e-15 55.5 0.1 1.9e-14 53.6 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CBY12280.1 - 5.1e-15 55.5 0.1 6.4e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CBY12280.1 - 4e-13 50.0 0.1 9.1e-13 48.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.19 CBY12280.1 - 2.2e-08 34.1 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CBY12280.1 - 7.3e-08 32.1 0.0 1.8e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 CBY12280.1 - 3.8e-07 29.7 0.1 1.1e-06 28.2 0.0 1.6 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 CBY12280.1 - 1e-05 24.6 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 CBY12280.1 - 1.3e-05 24.7 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.12 CBY12280.1 - 2.8e-05 23.7 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 CBY12280.1 - 4.8e-05 23.4 0.0 7.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBY12280.1 - 0.0046 16.5 0.1 0.0073 15.9 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 CBY12280.1 - 0.0049 16.2 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 CBY12280.1 - 0.0064 16.1 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.18 CBY12280.1 - 0.0069 15.9 0.0 0.029 13.9 0.0 1.9 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain DOT1 PF08123.13 CBY12280.1 - 0.0072 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 FtsJ PF01728.19 CBY12280.1 - 0.014 15.5 0.0 5.3 7.1 0.0 2.3 1 1 0 2 2 2 0 FtsJ-like methyltransferase UPF0020 PF01170.18 CBY12280.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_5 PF01795.19 CBY12280.1 - 0.04 13.4 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 MraW methylase family Methyltransf_4 PF02390.17 CBY12280.1 - 0.15 11.5 0.0 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PAN_4 PF14295.6 CBY12281.1 - 6.6 6.7 9.4 5.1 7.1 4.1 2.1 1 1 1 2 2 2 0 PAN domain Pet191_N PF10203.9 CBY12282.1 - 0.0058 16.9 0.9 0.0058 16.9 0.9 2.9 3 0 0 3 3 3 1 Cytochrome c oxidase assembly protein PET191 eIF2A PF08662.11 CBY12283.1 - 0.023 14.6 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A EGF_CA PF07645.15 CBY12284.1 - 1.9e-13 50.4 21.4 1.7e-09 37.7 8.5 10.3 8 4 1 9 9 9 4 Calcium-binding EGF domain EGF PF00008.27 CBY12284.1 - 8e-08 32.4 28.9 2.6e-06 27.6 4.8 10.0 9 3 2 11 11 11 4 EGF-like domain cEGF PF12662.7 CBY12284.1 - 1.3e-05 25.0 0.8 1.3e-05 25.0 0.8 8.0 8 1 0 8 8 8 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY12284.1 - 0.00017 21.7 19.3 0.00079 19.6 4.0 9.8 9 3 1 10 10 10 4 EGF domain hEGF PF12661.7 CBY12284.1 - 0.01 16.5 22.5 0.028 15.1 4.2 10.4 13 1 0 13 13 13 0 Human growth factor-like EGF Mur_ligase_M PF08245.12 CBY12285.1 - 5.5e-08 33.0 0.0 2.1e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CBY12285.1 - 0.062 13.5 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain zf-LSD1 PF06943.12 CBY12285.1 - 1.6 8.7 6.0 0.5 10.3 2.8 1.9 2 0 0 2 2 2 0 LSD1 zinc finger CUB PF00431.20 CBY12286.1 - 5.4e-49 165.1 6.5 2.7e-16 59.9 0.2 3.5 3 0 0 3 3 3 3 CUB domain Trypsin PF00089.26 CBY12286.1 - 1.2e-45 156.0 1.1 2.8e-45 154.9 1.1 1.7 1 0 0 1 1 1 1 Trypsin Astacin PF01400.24 CBY12286.1 - 1.6e-11 44.2 0.0 4.2e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF1986 PF09342.11 CBY12286.1 - 0.13 12.6 0.2 0.3 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) VCBS PF13517.6 CBY12287.1 - 3.1e-12 46.9 10.1 0.00073 20.1 0.0 3.8 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBY12287.1 - 0.00019 21.5 11.0 0.066 13.4 1.3 4.0 4 0 0 4 4 4 3 FG-GAP repeat Xlink PF00193.17 CBY12287.1 - 0.19 12.2 4.1 0.15 12.5 0.4 2.4 1 1 2 3 3 3 0 Extracellular link domain RT_RNaseH_2 PF17919.1 CBY12288.1 - 2e-18 66.2 0.0 2.1e-17 63.0 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY12288.1 - 1.4e-17 63.9 0.0 7.1e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY12288.1 - 1.1e-11 44.7 0.0 2.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY12288.1 - 9.3e-11 42.0 0.0 2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY12288.1 - 0.00074 19.6 0.2 0.0021 18.1 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain GBR2_CC PF18455.1 CBY12288.1 - 0.024 14.7 1.9 0.088 12.9 1.9 1.9 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain zf-CCHC PF00098.23 CBY12288.1 - 0.027 14.5 7.4 0.062 13.4 7.4 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 CBY12288.1 - 0.22 11.2 4.2 0.75 9.6 4.2 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RNB PF00773.19 CBY12292.1 - 9.3e-101 337.4 0.0 1.4e-100 336.8 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CBY12292.1 - 6.3e-18 64.6 0.0 1.5e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CBY12292.1 - 3.1e-14 52.9 0.0 5.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CBY12292.1 - 2.2e-13 49.9 0.6 2.2e-13 49.9 0.6 1.9 2 0 0 2 2 2 1 S1 domain PIN_4 PF13638.6 CBY12292.1 - 3.7e-09 37.0 0.0 1.5e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CBY12292.1 - 9e-08 32.2 0.1 9.3e-06 25.7 0.1 2.9 2 0 0 2 2 2 1 Cold shock domain Dis3l2_C_term PF17877.1 CBY12292.1 - 1.7e-05 25.0 0.0 4.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 CBY12292.1 - 0.018 14.7 0.0 0.088 12.5 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease B OB domain MRP-L28 PF09812.9 CBY12293.1 - 0.17 12.0 4.9 0.26 11.4 5.0 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 Histone PF00125.24 CBY12294.1 - 6.8e-54 181.7 2.3 7.6e-54 181.6 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY12294.1 - 8.4e-05 22.6 0.3 0.00015 21.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY12294.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY12294.1 - 0.00042 20.6 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY12294.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CBY12294.1 - 0.11 12.6 0.1 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CBY12295.1 - 3.3e-08 33.6 0.1 4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY12295.1 - 4.7e-05 23.5 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY12295.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY12295.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY12295.1 - 0.00033 21.0 0.2 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY12295.1 - 0.012 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY12295.1 - 0.046 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY12295.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Linker_histone PF00538.19 CBY12296.1 - 2e-28 98.5 1.0 2e-28 98.5 1.0 2.4 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 CBY12296.1 - 3.8e-06 27.1 56.2 3.8e-06 27.1 56.2 2.1 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 ASFV_J13L PF05568.11 CBY12296.1 - 7.5 6.3 11.6 4.3 7.1 9.6 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein Histone PF00125.24 CBY12297.1 - 6.3e-16 58.9 0.0 7.9e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY12297.1 - 4.3e-05 23.7 0.0 5.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 CBY12297.1 - 0.00026 20.6 0.0 0.00055 19.6 0.0 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY12298.1 - 1.4e-21 77.2 0.6 1.7e-21 76.9 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY12298.1 - 5.4e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY12298.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY12298.1 - 0.00041 20.4 0.3 0.00044 20.3 0.3 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY12298.1 - 0.033 14.4 0.7 0.087 13.1 0.7 1.7 1 1 0 1 1 1 0 CENP-W protein Histone_H2A_C PF16211.5 CBY12299.1 - 3.6e-20 71.4 1.3 5.6e-20 70.8 1.3 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY12299.1 - 5.3e-17 62.4 0.1 6.5e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY12299.1 - 5.6e-05 23.3 0.0 8.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY12300.1 - 1.4e-21 77.2 0.6 1.7e-21 76.9 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY12300.1 - 5.4e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY12300.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY12300.1 - 0.00041 20.4 0.3 0.00044 20.3 0.3 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY12300.1 - 0.033 14.4 0.7 0.087 13.1 0.7 1.7 1 1 0 1 1 1 0 CENP-W protein Insulin PF00049.18 CBY12301.1 - 0.012 16.6 9.2 0.026 15.5 0.3 2.8 1 1 1 2 2 2 0 Insulin/IGF/Relaxin family Pox_I3 PF04661.12 CBY12302.1 - 0.0082 15.3 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Poxvirus I3 ssDNA-binding protein Hormone_recep PF00104.30 CBY12302.1 - 0.022 14.4 0.7 0.048 13.2 0.5 1.9 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor DUF3865 PF12981.7 CBY12302.1 - 0.067 13.1 0.3 0.41 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3865) TPR_MLP1_2 PF07926.12 CBY12304.1 - 0.0018 18.4 7.0 0.011 15.9 3.6 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF5309 PF17236.2 CBY12304.1 - 0.0085 15.5 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5309) Syntaxin-6_N PF09177.11 CBY12304.1 - 0.028 15.0 5.0 3.1 8.4 0.1 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Spc7 PF08317.11 CBY12304.1 - 0.029 13.3 8.5 0.061 12.2 0.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 CBY12304.1 - 0.24 11.6 8.8 0.99 9.7 0.1 3.0 2 1 1 3 3 3 0 Cortexillin I, coiled coil DUF4407 PF14362.6 CBY12304.1 - 0.24 10.7 4.5 1 8.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 CBY12304.1 - 0.28 11.3 8.4 1.4 9.1 2.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FliJ PF02050.16 CBY12304.1 - 0.65 10.2 7.9 0.49 10.6 0.7 2.4 2 1 0 2 2 2 0 Flagellar FliJ protein She9_MDM33 PF05546.11 CBY12304.1 - 1.1 9.1 5.9 0.38 10.5 0.3 2.1 1 1 1 2 2 2 0 She9 / Mdm33 family FliD_N PF02465.18 CBY12304.1 - 1.5 9.6 4.5 2.3 9.0 0.1 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus NYD-SP28_assoc PF14775.6 CBY12304.1 - 2.5 8.2 5.9 10 6.3 0.2 3.3 3 1 0 3 3 3 0 Sperm tail C-terminal domain KLRAQ PF10205.9 CBY12304.1 - 2.7 8.3 9.7 1.8 8.9 4.3 2.7 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Spc42p PF11544.8 CBY12304.1 - 5.7 7.0 11.8 4.6 7.3 0.5 3.5 3 1 1 4 4 4 0 Spindle pole body component Spc42p Phospholip_A2_1 PF00068.19 CBY12305.1 - 4.9e-18 65.6 7.9 1.1e-17 64.5 7.9 1.5 1 0 0 1 1 1 1 Phospholipase A2 Tctex-1 PF03645.13 CBY12306.1 - 2.6e-10 40.5 0.1 9.5e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 Tctex-1 family Ion_trans PF00520.31 CBY12307.1 - 8.1e-39 133.3 20.2 5.9e-38 130.5 20.2 2.0 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CBY12307.1 - 3e-22 78.8 0.4 3e-22 78.8 0.4 2.3 3 0 0 3 3 3 1 BTB/POZ domain Ion_trans_2 PF07885.16 CBY12307.1 - 3.6e-11 42.9 9.8 3.6e-11 42.9 9.8 1.9 2 0 0 2 2 2 1 Ion channel PAN_1 PF00024.26 CBY12307.1 - 0.0064 16.4 10.0 0.017 15.1 10.0 1.7 1 1 0 1 1 1 1 PAN domain BTB_3 PF16017.5 CBY12307.1 - 0.018 15.1 0.1 0.077 13.1 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain Acetyltransf_1 PF00583.25 CBY12308.1 - 1.1e-07 32.1 0.0 1.3e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY12308.1 - 1.6e-06 28.0 0.0 2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY12308.1 - 0.00037 20.9 0.0 0.00055 20.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CBY12308.1 - 0.022 15.4 0.0 0.026 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 CBY12309.1 - 1.8e-09 37.5 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4459 PF14673.6 CBY12309.1 - 0.071 13.0 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) DUF1999 PF09390.10 CBY12309.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) MFS_1 PF07690.16 CBY12310.1 - 9.2e-13 47.8 5.5 1e-12 47.7 5.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY12310.1 - 4.9e-07 29.0 5.0 6.1e-07 28.7 5.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PUCC PF03209.15 CBY12310.1 - 0.011 14.7 6.2 0.12 11.3 0.2 2.0 1 1 1 2 2 2 0 PUCC protein MFS_2 PF13347.6 CBY12310.1 - 0.058 11.9 3.3 0.077 11.5 2.0 1.7 1 1 0 2 2 2 0 MFS/sugar transport protein UNC-93 PF05978.16 CBY12310.1 - 0.071 12.8 1.4 0.1 12.3 1.4 1.2 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 AMP-binding PF00501.28 CBY12311.1 - 1.2e-95 320.6 0.0 1.5e-95 320.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY12311.1 - 0.041 14.9 0.0 0.11 13.5 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain CMV_1a PF12467.8 CBY12311.1 - 0.39 11.1 1.6 6.2 7.2 0.3 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Ice_nucleation PF00818.17 CBY12311.1 - 9.9 6.5 11.0 2.9 8.1 0.2 3.7 3 0 0 3 3 3 0 Ice nucleation protein repeat MIP PF00230.20 CBY12312.1 - 3.9e-34 118.3 1.9 4.5e-34 118.1 1.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3271 PF11675.8 CBY12312.1 - 0.15 11.3 0.1 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Mab-21 PF03281.14 CBY12313.1 - 5.8e-24 84.9 0.0 8.8e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein Cytidylate_kin PF02224.18 CBY12315.1 - 0.045 13.5 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase Rab3-GTPase_cat PF13890.6 CBY12316.1 - 1.1e-40 138.9 2.8 6.9e-40 136.3 2.8 2.2 1 1 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit PHD PF00628.29 CBY12317.1 - 1e-06 28.5 7.9 2.1e-06 27.5 7.9 1.6 1 0 0 1 1 1 1 PHD-finger MAS20 PF02064.15 CBY12317.1 - 0.0011 19.1 1.1 0.1 12.7 0.1 2.3 2 0 0 2 2 2 2 MAS20 protein import receptor zf-HC5HC2H PF13771.6 CBY12317.1 - 0.013 15.8 1.9 0.03 14.6 1.9 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain BAR_3 PF16746.5 CBY12317.1 - 0.039 13.7 0.5 0.045 13.4 0.5 1.2 1 0 0 1 1 1 0 BAR domain of APPL family GEN1_C PF18380.1 CBY12317.1 - 0.14 13.1 5.6 0.26 12.2 5.6 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain zf-4CXXC_R1 PF10497.9 CBY12317.1 - 7.2 6.9 9.3 20 5.5 7.7 2.5 2 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Snf7 PF03357.21 CBY12318.1 - 9.9e-42 142.5 22.5 1.4e-41 142.0 22.5 1.2 1 0 0 1 1 1 1 Snf7 UCH PF00443.29 CBY12318.1 - 0.091 12.2 3.8 0.12 11.9 3.8 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DnaJ-X PF14308.6 CBY12318.1 - 0.78 9.1 18.3 0.25 10.7 15.6 1.6 1 1 0 1 1 1 0 X-domain of DnaJ-containing GrpE PF01025.19 CBY12318.1 - 0.78 9.4 12.2 1.3 8.6 12.2 1.4 1 0 0 1 1 1 0 GrpE HlyD_2 PF12700.7 CBY12318.1 - 0.8 8.4 11.9 1.1 7.9 11.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein RSRP PF17069.5 CBY12318.1 - 1.2 8.7 7.5 1.7 8.1 7.5 1.4 1 1 0 1 1 1 0 Arginine/Serine-Rich protein 1 Helicase_C PF00271.31 CBY12319.1 - 0.073 13.4 0.3 0.099 13.0 0.3 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Vinculin PF01044.19 CBY12320.1 - 1.8e-217 724.9 38.5 3.3e-122 409.6 15.4 2.0 2 0 0 2 2 2 2 Vinculin family TFX_C PF14601.6 CBY12320.1 - 0.0043 17.0 0.7 0.021 14.8 0.1 2.4 3 0 0 3 3 3 1 DNA_binding protein, TFX, C-term DUF4342 PF14242.6 CBY12320.1 - 0.034 14.1 0.0 0.4 10.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) PASTA PF03793.19 CBY12320.1 - 0.14 12.0 0.0 8.5 6.3 0.0 3.4 3 0 0 3 3 3 0 PASTA domain Rotamase PF00639.21 CBY12320.1 - 0.33 11.9 0.1 0.33 11.9 0.1 5.4 6 0 0 6 6 6 0 PPIC-type PPIASE domain T2SSF PF00482.23 CBY12320.1 - 8.8 6.3 7.5 11 6.0 0.0 4.5 5 1 1 6 6 6 0 Type II secretion system (T2SS), protein F Helicase_C PF00271.31 CBY12321.1 - 0.073 13.4 0.3 0.099 13.0 0.3 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Vinculin PF01044.19 CBY12322.1 - 2.9e-215 717.6 27.4 3.5e-215 717.4 27.4 1.0 1 0 0 1 1 1 1 Vinculin family TFX_C PF14601.6 CBY12322.1 - 0.0037 17.2 0.8 0.018 15.0 0.1 2.5 3 0 0 3 3 3 1 DNA_binding protein, TFX, C-term DUF4342 PF14242.6 CBY12322.1 - 0.026 14.5 0.0 0.35 10.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Hormone_recep PF00104.30 CBY12323.1 - 1.5e-14 54.1 2.6 4.5e-14 52.5 2.6 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MIEAP PF16026.5 CBY12323.1 - 0.065 13.5 1.1 0.22 11.7 0.1 2.3 1 1 2 3 3 3 0 Mitochondria-eating protein zf-C4 PF00105.18 CBY12324.1 - 4.3e-09 36.7 2.4 4.3e-09 36.7 2.4 2.1 2 1 0 2 2 2 1 Zinc finger, C4 type (two domains) CAP_assoc_N PF14504.6 CBY12324.1 - 0.036 13.8 0.4 0.065 13.0 0.4 1.4 1 0 0 1 1 1 0 CAP-associated N-terminal Stc1 PF12898.7 CBY12324.1 - 0.064 13.8 6.9 0.041 14.4 5.1 1.6 1 1 0 1 1 1 0 Stc1 domain PLATZ PF04640.14 CBY12324.1 - 7.5 7.3 8.3 40 4.9 8.3 2.2 1 1 0 1 1 1 0 PLATZ transcription factor Phage_hub_GP28 PF11110.8 CBY12326.1 - 0.029 14.3 0.3 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 Baseplate hub distal subunit DUF948 PF06103.11 CBY12326.1 - 0.23 11.8 2.7 3.1 8.1 0.3 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4208 PF13907.6 CBY12326.1 - 0.29 11.6 3.9 5 7.6 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) PLC-beta_C PF08703.10 CBY12326.1 - 1.3 9.0 20.1 0.052 13.5 12.4 2.3 2 1 0 2 2 2 0 PLC-beta C terminal DUF1664 PF07889.12 CBY12326.1 - 1.6 8.8 6.7 0.84 9.7 2.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) RNA_pol_3_Rpc31 PF11705.8 CBY12327.1 - 0.00035 20.9 3.5 0.00035 20.9 3.5 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PSK_trans_fac PF07704.11 CBY12327.1 - 0.043 14.6 5.8 0.11 13.3 5.8 1.7 1 1 0 1 1 1 0 Rv0623-like transcription factor DUF1676 PF07898.13 CBY12327.1 - 5.8 6.9 6.3 19 5.2 6.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) IRK_C PF17655.1 CBY12328.1 - 0.04 13.5 0.5 0.14 11.7 0.1 1.8 1 1 1 2 2 2 0 Inward rectifier potassium channel C-terminal domain IRK_C PF17655.1 CBY12329.1 - 1.3e-60 204.0 0.5 2.8e-58 196.4 0.5 2.2 1 1 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY12329.1 - 2.9e-27 95.2 0.2 4.9e-27 94.5 0.2 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY12329.1 - 0.057 13.4 1.5 0.13 12.3 1.5 1.6 1 0 0 1 1 1 0 Ion channel Pkinase PF00069.25 CBY12331.1 - 6.9e-57 192.8 0.0 2.1e-56 191.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 CBY12331.1 - 1.2e-36 124.6 0.1 4.1e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY12331.1 - 4e-23 82.0 0.0 1.2e-22 80.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY12331.1 - 0.012 15.0 0.0 0.036 13.4 0.0 1.9 1 0 0 1 1 1 0 Kinase-like T3SS_needle_E PF08988.10 CBY12331.1 - 0.033 14.3 5.0 0.71 10.1 1.0 3.0 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Phage_GP20 PF06810.11 CBY12331.1 - 0.037 13.8 30.6 0.064 13.1 11.3 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF3584 PF12128.8 CBY12331.1 - 0.056 11.0 12.4 0.086 10.3 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DEAD PF00270.29 CBY12331.1 - 0.08 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase APH PF01636.23 CBY12331.1 - 0.081 12.8 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Csm1_N PF18504.1 CBY12331.1 - 0.14 12.5 15.4 0.31 11.4 2.6 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain RRF_GI PF12614.8 CBY12331.1 - 0.21 11.7 2.8 0.53 10.5 2.8 1.6 1 0 0 1 1 1 0 Ribosome recycling factor PKcGMP_CC PF16808.5 CBY12331.1 - 0.26 11.2 13.6 1.1 9.2 0.4 3.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Med4 PF10018.9 CBY12331.1 - 0.51 10.0 12.8 0.13 11.9 2.1 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Baculo_PEP_C PF04513.12 CBY12331.1 - 2.1 8.4 6.8 17 5.5 6.8 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 CBY12331.1 - 2.1 7.6 7.1 3.9 6.7 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlgN PF05130.12 CBY12331.1 - 4.7 7.7 14.4 0.045 14.3 3.9 2.6 2 1 0 2 2 2 0 FlgN protein FGF PF00167.18 CBY12333.1 - 5.1e-36 123.5 0.5 6.5e-36 123.2 0.5 1.1 1 0 0 1 1 1 1 Fibroblast growth factor HU-CCDC81_euk_1 PF14908.6 CBY12334.1 - 0.054 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 LZ_Tnp_IS66 PF13007.7 CBY12334.1 - 1.3 9.9 4.9 0.4 11.5 1.9 1.7 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain EGF_CA PF07645.15 CBY12336.1 - 5.5e-105 343.4 244.1 9.7e-10 38.5 6.6 15.5 15 0 0 15 15 15 14 Calcium-binding EGF domain cEGF PF12662.7 CBY12336.1 - 3.6e-46 154.7 128.5 8.9e-06 25.5 1.3 17.0 16 0 0 16 16 16 13 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY12336.1 - 3.8e-41 139.0 184.0 2.4e-08 34.0 6.6 16.3 14 2 0 15 15 15 13 EGF domain EGF PF00008.27 CBY12336.1 - 7.1e-23 80.6 165.5 7.9e-05 22.9 2.7 16.4 15 0 0 15 15 15 13 EGF-like domain hEGF PF12661.7 CBY12336.1 - 6.1e-15 55.2 171.2 0.00023 21.7 4.3 18.7 20 0 0 20 20 20 11 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY12336.1 - 4.8e-12 45.9 181.1 0.082 13.2 6.6 15.8 12 3 3 15 15 15 13 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY12336.1 - 8.9e-12 44.9 48.5 3e-06 27.2 7.7 14.9 15 0 0 15 15 15 9 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY12336.1 - 1.6e-07 31.5 175.9 0.00011 22.4 10.4 15.0 13 1 0 14 14 14 8 Pvs28 EGF domain Thioredoxin PF00085.20 CBY12337.1 - 3e-56 187.7 2.2 7.2e-28 96.6 0.2 2.0 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CBY12337.1 - 6e-11 42.8 3.0 5.7e-05 23.5 0.1 3.1 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY12337.1 - 6.3e-11 42.3 0.9 4.5e-05 23.4 0.1 2.4 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CBY12337.1 - 2.1e-09 37.6 0.2 0.011 16.0 0.0 3.9 2 2 1 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.6 CBY12337.1 - 3.2e-08 33.6 0.1 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 CBY12337.1 - 2.9e-07 30.3 0.1 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.6 CBY12337.1 - 2.2e-05 24.7 0.5 0.38 10.9 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.6 CBY12337.1 - 7.5e-05 22.7 0.2 0.053 13.6 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin domain OST3_OST6 PF04756.13 CBY12337.1 - 0.0013 18.1 0.1 0.24 10.7 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family TraF PF13728.6 CBY12337.1 - 0.0016 18.3 0.0 0.085 12.7 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein zf_PR_Knuckle PF18445.1 CBY12337.1 - 0.0091 15.8 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 1 PR zinc knuckle motif Glutaredoxin PF00462.24 CBY12337.1 - 0.012 15.8 4.7 1.6 9.0 0.2 3.3 2 2 0 2 2 2 0 Glutaredoxin Thioredoxin_9 PF14595.6 CBY12337.1 - 0.049 13.4 0.2 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin KCT2 PF17818.1 CBY12339.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Keratinocyte-associated gene product TssO PF17561.2 CBY12339.1 - 5.6 7.1 5.8 1.5 9.0 1.0 1.9 1 1 1 2 2 2 0 Type VI secretion system, TssO TMEM51 PF15345.6 CBY12341.1 - 0.24 11.2 0.9 0.34 10.7 0.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 UBA2_C PF16195.5 CBY12342.1 - 0.052 14.2 0.2 0.079 13.6 0.2 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Voltage_CLC PF00654.20 CBY12344.1 - 6.1e-90 302.0 23.0 3.8e-89 299.4 21.9 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBY12344.1 - 1.7e-12 47.5 0.1 7e-07 29.6 0.2 2.7 2 0 0 2 2 2 2 CBS domain VirE1 PF12189.8 CBY12344.1 - 0.13 12.4 0.0 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 Single-strand DNA-binding protein Tub PF01167.18 CBY12345.1 - 1.3e-76 257.6 0.3 1.8e-76 257.1 0.3 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 CBY12345.1 - 2.9 7.4 5.8 0.93 9.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3527) AMP-binding PF00501.28 CBY12346.1 - 4.7e-39 134.2 0.5 6.5e-39 133.7 0.5 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY12346.1 - 1.9e-12 48.0 0.0 4.9e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 CBY12346.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CBY12347.1 - 6.6e-93 311.6 0.0 8e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY12347.1 - 6.8e-17 62.2 0.0 1.9e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain E2_bind PF08825.10 CBY12347.1 - 0.018 15.1 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 E2 binding domain AA_permease_2 PF13520.6 CBY12348.1 - 1.4e-54 185.6 37.1 1.7e-54 185.3 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY12348.1 - 1.1e-27 96.8 33.3 1.4e-27 96.4 33.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 CBY12348.1 - 2.8 8.4 6.3 33 5.0 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ABC2_membrane PF01061.24 CBY12349.1 - 2.8e-43 147.8 26.6 2.8e-43 147.8 26.6 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CBY12349.1 - 3.2e-29 102.2 0.1 4.8e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY12349.1 - 3.1e-10 40.4 0.0 4.3e-05 23.5 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY12349.1 - 1.9e-08 34.0 0.3 1.6e-07 31.0 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY12349.1 - 1.6e-05 24.9 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 CBY12349.1 - 0.00015 21.0 18.5 0.00026 20.2 18.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein Rad17 PF03215.15 CBY12349.1 - 0.00085 19.3 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 CBY12349.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CBY12349.1 - 0.0046 16.7 0.3 0.011 15.5 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CBY12349.1 - 0.0052 17.2 0.0 0.009 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 CBY12349.1 - 0.026 14.6 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 CBY12349.1 - 0.028 14.7 0.6 0.18 12.1 0.6 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBY12349.1 - 0.029 14.9 0.3 0.07 13.6 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBY12349.1 - 0.037 13.6 0.2 0.069 12.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY12349.1 - 0.068 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 CBY12349.1 - 0.081 11.6 0.1 0.37 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBY12349.1 - 0.14 12.6 0.0 0.57 10.6 0.0 2.0 1 1 0 2 2 2 0 RNA helicase Kringle PF00051.18 CBY12350.1 - 4.6e-09 36.5 4.0 4.6e-09 36.5 4.0 2.0 2 0 0 2 2 2 1 Kringle domain zf-LITAF-like PF10601.9 CBY12351.1 - 0.18 12.1 23.9 2 8.8 16.5 3.3 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain SieB PF14163.6 CBY12352.1 - 1.3 8.5 11.0 0.44 10.0 1.6 2.0 1 1 1 2 2 2 0 Super-infection exclusion protein B Bax1-I PF01027.20 CBY12353.1 - 7.3e-16 58.6 10.7 8.8e-16 58.3 10.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2244 PF10003.9 CBY12353.1 - 0.17 11.5 1.3 0.26 11.0 0.1 1.8 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) MotA_ExbB PF01618.16 CBY12353.1 - 0.92 9.3 4.1 13 5.6 0.3 2.2 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Ost5 PF05251.12 CBY12353.1 - 5.1 7.4 12.9 1.7 8.9 0.2 3.3 2 2 1 3 3 3 0 Oligosaccharyltransferase subunit 5 BAR PF03114.18 CBY12354.1 - 0.11 12.2 3.9 0.2 11.3 1.5 2.6 1 1 1 2 2 2 0 BAR domain Baculo_PEP_C PF04513.12 CBY12354.1 - 0.16 12.0 6.2 20 5.2 0.1 3.9 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 CBY12354.1 - 0.2 11.9 0.2 0.2 11.9 0.2 3.6 3 1 0 3 3 3 0 Uncharacterized conserved protein Nsp1_C PF05064.13 CBY12354.1 - 0.23 11.3 9.2 0.084 12.7 0.5 3.3 4 0 0 4 4 4 0 Nsp1-like C-terminal region GldM_N PF12081.8 CBY12354.1 - 0.55 10.3 7.2 0.34 11.0 2.9 2.5 1 1 0 2 2 2 0 GldM N-terminal domain Fez1 PF06818.15 CBY12354.1 - 0.75 10.2 18.8 1.8 8.9 4.5 2.5 1 1 1 2 2 2 0 Fez1 DUF1515 PF07439.11 CBY12354.1 - 1 9.4 7.1 0.21 11.6 0.2 3.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1515) Hrs_helical PF12210.8 CBY12354.1 - 1.4 9.5 5.0 24 5.5 0.1 3.1 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate LPP PF04728.13 CBY12354.1 - 2.7 8.4 5.4 10 6.6 0.1 4.0 3 1 1 4 4 4 0 Lipoprotein leucine-zipper DUF2203 PF09969.9 CBY12354.1 - 9.6 7.0 10.4 1.6 9.4 0.7 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Endonuc_Holl PF10107.9 CBY12355.1 - 0.075 12.9 0.1 0.075 12.9 0.1 1.8 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Sulfotransfer_2 PF03567.14 CBY12357.1 - 5.9e-18 65.7 0.3 8.3e-18 65.2 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY12357.1 - 0.0007 19.2 0.3 0.0024 17.4 0.3 1.8 1 1 0 1 1 1 1 Sulfotransferase domain NLRC4_HD2 PF17776.1 CBY12357.1 - 0.063 13.8 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 NLRC4 helical domain HD2 DFF40 PF09230.10 CBY12358.1 - 0.039 13.6 1.3 0.066 12.8 1.0 1.5 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa HypD PF01924.16 CBY12359.1 - 0.045 12.8 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family ANAPC4_WD40 PF12894.7 CBY12360.1 - 7.9e-08 32.5 1.7 0.003 17.8 0.1 4.9 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY12360.1 - 0.0098 16.7 14.1 0.16 12.9 0.2 5.0 4 1 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CBY12360.1 - 0.095 11.7 0.2 11 4.9 0.0 2.4 1 1 1 2 2 2 0 Coatomer WD associated region DUF4315 PF14193.6 CBY12361.1 - 0.02 14.9 5.3 0.02 14.9 5.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) COMMD1_N PF17221.3 CBY12361.1 - 0.075 13.3 3.0 0.14 12.5 0.6 2.2 1 1 1 2 2 2 0 COMMD1 N-terminal domain PhoU PF01895.19 CBY12361.1 - 0.28 11.7 5.2 0.21 12.1 2.9 1.9 1 1 1 2 2 2 0 PhoU domain Seryl_tRNA_N PF02403.22 CBY12361.1 - 0.47 10.7 15.9 0.3 11.3 7.0 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 CBY12361.1 - 0.56 9.4 7.2 0.7 9.1 7.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein MADF_DNA_bdg PF10545.9 CBY12361.1 - 0.66 10.3 7.9 0.083 13.2 1.4 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PriA_C PF18074.1 CBY12361.1 - 0.7 10.7 4.0 0.6 11.0 1.3 2.3 1 1 1 2 2 2 0 Primosomal protein N C-terminal domain Vir_act_alpha_C PF10400.9 CBY12361.1 - 3.9 8.2 8.4 25 5.6 0.6 2.8 1 1 1 2 2 2 0 Virulence activator alpha C-term YabA PF06156.13 CBY12361.1 - 5.2 7.8 9.8 13 6.5 2.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA TTL PF03133.15 CBY12362.1 - 2.5e-84 282.9 3.6 3.4e-84 282.5 3.6 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY12362.1 - 3.9e-08 32.9 0.7 0.0029 16.9 0.0 3.1 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY12362.1 - 6.8e-05 22.2 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 CBY12362.1 - 0.012 15.2 0.0 3.8 7.1 0.0 2.5 2 1 0 2 2 2 0 RimK-like ATP-grasp domain Ribosomal_L29e PF01779.17 CBY12363.1 - 1.2e-18 67.1 8.0 1.7e-18 66.7 8.0 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family ALAD PF00490.21 CBY12365.1 - 1.7e-111 372.5 0.0 2.1e-111 372.1 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase EF_TS PF00889.19 CBY12366.1 - 8.4e-09 35.3 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor TS TAP_C PF03943.13 CBY12366.1 - 8e-05 22.2 0.4 0.00025 20.6 0.1 2.0 2 0 0 2 2 2 1 TAP C-terminal domain UBA PF00627.31 CBY12366.1 - 0.022 14.6 0.1 0.073 13.0 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain UBA_4 PF14555.6 CBY12366.1 - 0.088 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Arm PF00514.23 CBY12367.1 - 1.9e-05 24.5 0.6 0.088 12.9 0.1 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat ACT_7 PF13840.6 CBY12367.1 - 0.051 13.4 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 ACT domain Tom6 PF17112.5 CBY12368.1 - 0.034 13.6 0.4 0.034 13.6 0.4 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal BTP PF05232.12 CBY12368.1 - 0.14 12.2 4.3 0.18 11.9 4.3 1.2 1 0 0 1 1 1 0 Chlorhexidine efflux transporter RseC_MucC PF04246.12 CBY12368.1 - 0.3 11.0 4.6 0.33 10.9 4.6 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC FUSC-like PF12805.7 CBY12368.1 - 4.2 6.4 6.2 5.1 6.1 6.2 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF410 PF04190.13 CBY12369.1 - 5.4e-49 167.3 0.9 5.4e-49 167.3 0.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF410) Rep_Org_C PF06926.11 CBY12369.1 - 0.0095 16.2 0.7 0.14 12.5 0.1 2.6 3 0 0 3 3 3 1 Putative replisome organiser protein C-terminus Xpo1 PF08389.12 CBY12369.1 - 0.019 15.0 0.3 0.087 12.9 0.1 2.1 2 0 0 2 2 2 0 Exportin 1-like protein Vps39_1 PF10366.9 CBY12369.1 - 0.026 14.8 0.4 0.062 13.6 0.4 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 RPN6_N PF18055.1 CBY12369.1 - 0.095 13.1 1.2 0.16 12.3 0.5 1.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Malic_M PF03949.15 CBY12370.1 - 7.1e-92 307.3 0.0 9.6e-92 306.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CBY12370.1 - 2.4e-79 265.4 0.0 4.2e-79 264.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Utp14 PF04615.13 CBY12371.1 - 2.5e-93 314.1 59.6 6.5e-48 163.9 49.8 2.1 1 1 1 2 2 2 2 Utp14 protein DUF2270 PF10028.9 CBY12371.1 - 0.21 11.2 1.2 0.36 10.4 1.2 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) Nucleopor_Nup85 PF07575.13 CBY12372.1 - 1.5e-51 175.7 12.6 2.4e-51 175.0 12.6 1.3 1 1 0 1 1 1 1 Nup85 Nucleoporin FAP206 PF12018.8 CBY12373.1 - 1.4e-77 260.9 0.9 2.5e-77 260.1 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function CRIC_ras_sig PF10534.9 CBY12373.1 - 0.084 13.1 0.4 0.46 10.7 0.0 2.4 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras SAC3_GANP PF03399.16 CBY12374.1 - 3.7e-39 134.9 2.5 5.5e-39 134.3 2.5 1.2 1 0 0 1 1 1 1 SAC3/GANP family Fungal_trans_2 PF11951.8 CBY12374.1 - 0.022 13.6 0.8 0.039 12.8 0.8 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Activin_recp PF01064.23 CBY12374.1 - 2 9.5 5.5 1.7 9.8 1.3 2.7 1 1 1 2 2 2 0 Activin types I and II receptor domain DSPc PF00782.20 CBY12375.1 - 2.6e-12 46.7 0.0 4.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBY12375.1 - 0.0013 18.4 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY12375.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family HisK_sensor PF18698.1 CBY12375.1 - 0.038 14.4 0.2 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase sensor domain PTPlike_phytase PF14566.6 CBY12375.1 - 0.082 13.0 0.2 0.15 12.1 0.0 1.5 2 0 0 2 2 2 0 Inositol hexakisphosphate RRM_1 PF00076.22 CBY12376.1 - 2.8e-05 23.8 0.0 0.00078 19.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.32 CBY12377.1 - 8.6e-15 53.1 4.2 5.3e-05 22.5 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY12377.1 - 1.1e-14 54.7 6.0 1.6e-14 54.1 0.5 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY12377.1 - 1.8e-10 39.8 8.0 0.00016 21.4 0.1 4.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CBY12377.1 - 5.1e-08 32.6 2.4 0.0022 17.8 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY12377.1 - 5.1e-07 28.9 5.3 0.00028 20.2 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 CBY12377.1 - 0.21 11.5 3.2 6.1 6.8 0.1 3.8 3 1 1 4 4 4 0 EF hand Sulfotransfer_2 PF03567.14 CBY12378.1 - 2.8e-14 53.6 5.1 4.2e-14 53.1 5.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY12378.1 - 0.0038 16.7 1.1 0.024 14.1 0.5 2.2 1 1 1 2 2 2 1 Sulfotransferase domain Acatn PF13000.7 CBY12379.1 - 3e-93 313.2 24.5 3.1e-57 194.3 10.6 3.9 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Ceramidase PF05875.12 CBY12379.1 - 0.00044 19.8 3.1 0.00093 18.7 0.1 2.3 2 0 0 2 2 2 1 Ceramidase DUF1218 PF06749.12 CBY12379.1 - 0.11 13.0 0.4 0.11 13.0 0.4 2.7 3 2 1 4 4 4 0 Protein of unknown function (DUF1218) Phage_holin_4_1 PF05105.12 CBY12379.1 - 0.13 12.4 8.5 0.078 13.1 0.9 3.2 3 0 0 3 3 3 0 Bacteriophage holin family DUF2614 PF11023.8 CBY12379.1 - 0.66 10.1 3.8 5.8 7.0 0.7 3.1 2 1 1 3 3 3 0 Zinc-ribbon containing domain DUF4491 PF14898.6 CBY12379.1 - 3.9 8.0 6.2 1.6 9.2 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Peptidase_C50 PF03568.17 CBY12380.1 - 4.8e-38 131.3 0.2 9.4e-37 127.1 0.0 2.0 2 0 0 2 2 2 2 Peptidase family C50 CHAT PF12770.7 CBY12380.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 CHAT domain AAA_5 PF07728.14 CBY12382.1 - 7.2e-126 414.8 0.0 4.8e-26 91.4 0.0 7.5 7 0 0 7 7 7 7 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY12382.1 - 1.7e-30 105.9 0.0 8.5e-07 28.7 0.1 6.9 7 0 0 7 7 7 5 P-loop containing dynein motor region AAA PF00004.29 CBY12382.1 - 3.3e-27 95.5 0.0 0.00032 21.1 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 CBY12382.1 - 5.1e-26 91.1 0.0 2.1e-07 30.9 0.0 7.5 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 CBY12382.1 - 1.8e-23 82.8 6.5 4.5e-12 46.1 0.1 5.7 5 0 0 5 5 5 2 Midasin AAA lid domain AAA_lid_5 PF17865.1 CBY12382.1 - 4e-21 75.1 0.0 1.7e-20 73.1 0.0 2.2 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_16 PF13191.6 CBY12382.1 - 1.7e-20 74.1 11.4 0.024 15.0 0.6 7.7 7 2 0 7 7 6 6 AAA ATPase domain AAA_22 PF13401.6 CBY12382.1 - 1.3e-18 67.6 0.3 0.031 14.5 0.0 7.7 6 1 0 6 6 6 4 AAA domain AAA_30 PF13604.6 CBY12382.1 - 1.9e-18 66.9 0.0 0.0017 18.1 0.0 6.9 6 1 1 7 7 7 3 AAA domain Sigma54_activat PF00158.26 CBY12382.1 - 2.4e-18 66.4 0.1 0.038 13.7 0.0 7.2 7 1 0 7 7 6 3 Sigma-54 interaction domain TsaE PF02367.17 CBY12382.1 - 2.1e-16 60.1 0.3 0.27 11.2 0.0 6.4 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CBY12382.1 - 4.5e-16 59.6 0.0 0.036 14.6 0.0 6.9 6 0 0 6 6 6 2 AAA domain Dynein_heavy PF03028.15 CBY12382.1 - 5.3e-16 58.8 0.0 0.26 11.4 0.0 6.7 6 0 0 6 6 6 4 Dynein heavy chain region D6 P-loop domain ABC_tran PF00005.27 CBY12382.1 - 5.7e-16 59.3 1.6 0.016 15.7 0.0 6.6 6 0 0 6 6 6 3 ABC transporter Sigma54_activ_2 PF14532.6 CBY12382.1 - 3.4e-15 56.4 0.1 0.00022 21.3 0.0 6.7 6 0 0 6 6 6 2 Sigma-54 interaction domain RsgA_GTPase PF03193.16 CBY12382.1 - 1e-13 51.5 0.7 0.06 13.2 0.0 6.6 6 0 0 6 6 6 2 RsgA GTPase AAA_6 PF12774.7 CBY12382.1 - 1.8e-13 50.2 0.0 0.052 12.5 0.0 6.7 7 0 0 7 7 6 3 Hydrolytic ATP binding site of dynein motor region DUF815 PF05673.13 CBY12382.1 - 7e-13 48.3 0.4 0.028 13.6 0.0 6.3 6 0 0 6 6 6 3 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CBY12382.1 - 9.6e-12 45.2 0.9 2 8.9 0.0 6.7 6 0 0 6 6 6 1 RNA helicase MCM PF00493.23 CBY12382.1 - 2e-11 43.5 0.0 0.23 10.5 0.0 5.8 6 0 0 6 6 6 3 MCM P-loop domain AAA_28 PF13521.6 CBY12382.1 - 7.6e-11 42.5 4.8 0.53 10.5 0.0 6.4 7 0 0 7 7 5 3 AAA domain Mg_chelatase PF01078.21 CBY12382.1 - 7.8e-11 41.7 0.5 1.7 8.0 0.0 8.4 8 0 0 8 8 8 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CBY12382.1 - 1.1e-10 42.0 5.2 0.3 11.4 0.0 7.1 7 0 0 7 7 7 2 AAA domain AAA_14 PF13173.6 CBY12382.1 - 2.3e-10 40.6 0.0 0.36 10.9 0.0 7.1 7 0 0 7 7 7 2 AAA domain T2SSE PF00437.20 CBY12382.1 - 3.3e-10 39.5 1.0 0.16 11.0 0.0 5.0 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_29 PF13555.6 CBY12382.1 - 5.2e-10 38.9 2.9 1.3 8.9 0.0 6.5 6 0 0 6 6 6 2 P-loop containing region of AAA domain RuvB_N PF05496.12 CBY12382.1 - 6e-10 39.1 3.4 0.51 10.1 0.2 7.0 6 1 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CBY12382.1 - 1.5e-09 38.0 8.1 2.2 8.2 0.0 6.8 6 0 0 6 6 6 1 NACHT domain IstB_IS21 PF01695.17 CBY12382.1 - 2.5e-09 37.1 0.1 0.56 9.9 0.0 6.4 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_33 PF13671.6 CBY12382.1 - 4.6e-09 36.6 0.9 4.9 7.3 0.0 6.4 6 0 0 6 6 6 0 AAA domain AAA_24 PF13479.6 CBY12382.1 - 5e-09 36.2 0.1 5.1 6.8 0.0 6.7 7 0 0 7 7 6 0 AAA domain Roc PF08477.13 CBY12382.1 - 1.4e-08 35.0 3.4 10 6.3 0.0 6.4 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 CBY12382.1 - 2.4e-08 33.5 1.2 4.6 6.5 0.0 6.3 6 0 0 6 6 6 0 Zeta toxin AAA_25 PF13481.6 CBY12382.1 - 2.7e-08 33.6 0.8 0.59 9.7 0.0 5.9 7 0 0 7 7 6 1 AAA domain Rad17 PF03215.15 CBY12382.1 - 5.9e-08 32.8 0.2 0.026 14.5 0.1 5.6 5 0 0 5 5 5 1 Rad17 P-loop domain Bac_DnaA PF00308.18 CBY12382.1 - 1.3e-07 31.7 0.3 0.098 12.5 0.0 5.1 5 0 0 5 5 5 2 Bacterial dnaA protein Viral_helicase1 PF01443.18 CBY12382.1 - 1.3e-07 31.6 0.0 0.13 12.0 0.0 5.9 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 CBY12382.1 - 1.6e-07 31.1 4.5 0.047 13.4 0.0 5.5 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CBY12382.1 - 2.5e-07 30.8 0.6 23 5.1 0.0 6.4 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CBY12382.1 - 5.6e-07 30.3 1.7 0.13 12.7 0.0 5.4 6 0 0 6 6 5 1 AAA domain AAA_8 PF12780.7 CBY12382.1 - 1.9e-06 27.4 0.3 2.3 7.5 0.0 5.8 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 ResIII PF04851.15 CBY12382.1 - 7.2e-06 26.1 0.2 1.5 8.8 0.0 5.0 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 CBY12382.1 - 1.6e-05 24.6 5.0 8.6 5.9 0.0 5.6 6 0 0 6 6 5 0 SRP54-type protein, GTPase domain ATPase PF06745.13 CBY12382.1 - 5e-05 22.8 1.1 2.4 7.4 0.0 5.4 6 0 0 6 6 6 1 KaiC PhoH PF02562.16 CBY12382.1 - 5.1e-05 22.8 1.0 1 8.8 0.0 5.2 6 0 0 6 6 5 1 PhoH-like protein TniB PF05621.11 CBY12382.1 - 9.1e-05 21.9 0.3 14 5.0 0.0 5.7 6 0 0 6 6 6 0 Bacterial TniB protein AAA_11 PF13086.6 CBY12382.1 - 0.00016 21.6 0.4 49 3.6 0.0 5.4 5 0 0 5 5 5 0 AAA domain SRPRB PF09439.10 CBY12382.1 - 0.00025 20.6 1.3 2.2 7.7 0.0 4.8 5 0 0 5 5 4 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 CBY12382.1 - 0.00038 20.3 5.2 0.45 10.3 0.0 5.0 5 0 0 5 5 5 1 Conserved hypothetical ATP binding protein Septin PF00735.18 CBY12382.1 - 0.00047 19.5 1.4 3.7 6.7 0.0 5.1 6 0 0 6 6 5 0 Septin DEAD PF00270.29 CBY12382.1 - 0.00085 19.1 0.0 1.8 8.3 0.0 4.2 4 0 0 4 4 3 1 DEAD/DEAH box helicase NB-ARC PF00931.22 CBY12382.1 - 0.0012 18.0 2.7 1.3 8.2 0.0 4.6 5 0 0 5 5 5 1 NB-ARC domain NTPase_1 PF03266.15 CBY12382.1 - 0.0017 18.3 10.4 9.2 6.1 0.0 5.8 6 0 0 6 6 5 0 NTPase ATPase_2 PF01637.18 CBY12382.1 - 0.0026 17.7 0.1 19 5.1 0.0 4.9 5 0 0 5 5 5 0 ATPase domain predominantly from Archaea IPT PF01745.16 CBY12382.1 - 0.0033 16.8 2.8 7.4 5.9 0.0 4.7 5 0 0 5 5 5 0 Isopentenyl transferase dNK PF01712.19 CBY12382.1 - 0.0079 16.1 6.9 30 4.4 0.0 5.7 6 0 0 6 6 5 0 Deoxynucleoside kinase TIP49 PF06068.13 CBY12382.1 - 0.0083 15.4 2.7 50 2.9 0.0 5.0 6 0 0 6 6 5 0 TIP49 P-loop domain cobW PF02492.19 CBY12382.1 - 0.019 14.6 6.1 5.3 6.6 0.2 5.3 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 CBY12382.1 - 0.025 14.4 0.6 6.5 6.5 0.0 4.3 5 0 0 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Parvo_NS1 PF01057.17 CBY12382.1 - 0.027 13.5 0.1 2 7.4 0.0 3.3 4 0 0 4 4 3 0 Parvovirus non-structural protein NS1 AAA_15 PF13175.6 CBY12382.1 - 0.037 13.8 0.3 3.8 7.1 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 CBY12382.1 - 0.074 12.0 0.6 33 3.2 0.1 4.2 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 CBY12382.1 - 0.092 12.1 2.0 9.9 5.4 0.0 4.0 5 0 0 5 5 3 0 FtsK/SpoIIIE family AAA_17 PF13207.6 CBY12382.1 - 0.31 11.5 4.1 57 4.1 0.0 4.6 4 0 0 4 4 4 0 AAA domain Ras PF00071.22 CBY12382.1 - 5.6 6.5 8.3 1.2e+02 2.2 0.1 5.5 6 0 0 6 6 6 0 Ras family CPT PF07931.12 CBY12382.1 - 9.3 6.1 7.4 80 3.0 0.0 5.5 5 2 0 5 5 4 0 Chloramphenicol phosphotransferase-like protein Connexin PF00029.19 CBY12383.1 - 7.6e-37 127.3 7.3 9.6e-29 100.8 0.1 2.0 1 1 1 2 2 2 2 Connexin zf-H2C2_2 PF13465.6 CBY12384.1 - 1.4e-35 120.1 64.6 1.1e-08 35.1 0.3 9.4 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2 PF00096.26 CBY12384.1 - 5.4e-24 83.3 67.7 0.00023 21.4 2.5 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY12384.1 - 3e-18 65.0 64.1 0.006 17.3 1.2 8.7 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY12384.1 - 1.1e-07 31.4 10.1 9.4e-05 22.1 4.3 7.3 8 2 0 8 8 6 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 CBY12384.1 - 3e-06 27.4 40.4 0.00047 20.4 7.1 5.6 3 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CBY12384.1 - 0.0026 18.0 0.1 0.0026 18.0 0.1 7.2 6 1 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CBY12384.1 - 0.044 13.6 0.9 0.044 13.6 0.9 7.3 8 1 0 8 8 8 0 zinc-finger C2H2-type GAGA PF09237.11 CBY12384.1 - 0.081 12.7 15.1 4.7 7.1 0.2 5.5 3 2 2 5 5 5 0 GAGA factor zf-MYST PF17772.1 CBY12384.1 - 0.12 12.0 0.2 0.12 12.0 0.2 3.8 4 1 1 5 5 5 0 MYST family zinc finger domain WG_beta_rep PF14903.6 CBY12384.1 - 0.2 12.0 0.4 0.68 10.3 0.3 1.9 2 0 0 2 2 2 0 WG containing repeat PriA_CRR PF18319.1 CBY12384.1 - 0.48 10.5 11.2 10 6.2 1.9 4.4 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2_8 PF15909.5 CBY12384.1 - 0.5 10.7 32.0 0.82 10.0 3.8 4.3 1 1 2 4 4 4 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 CBY12384.1 - 6.6 7.6 21.2 2.9 8.7 0.3 4.2 1 1 2 4 4 4 0 zinc-ribbon family tRNA_synt_1c_R2 PF04557.15 CBY12385.1 - 0.072 14.0 6.0 0.093 13.7 6.0 1.0 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Na_H_Exchanger PF00999.21 CBY12386.1 - 3.6e-55 187.3 36.4 4.3e-54 183.8 32.8 1.9 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family RRM_3 PF08777.11 CBY12387.1 - 0.02 14.9 0.3 0.029 14.4 0.3 1.3 1 0 0 1 1 1 0 RNA binding motif Pkinase_Tyr PF07714.17 CBY12388.1 - 5.7e-64 215.9 0.0 9.2e-64 215.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY12388.1 - 8.1e-34 117.2 0.0 1.5e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CBY12388.1 - 0.0055 15.7 0.3 0.0055 15.7 0.3 2.7 2 1 1 3 3 3 1 Haspin like kinase domain AdoHcyase PF05221.17 CBY12388.1 - 0.035 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Kinase-like PF14531.6 CBY12388.1 - 0.092 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PRESAN PF09687.10 CBY12388.1 - 0.32 11.5 2.6 26 5.4 0.1 3.0 3 0 0 3 3 3 0 Plasmodium RESA N-terminal Kelch_1 PF01344.25 CBY12389.1 - 1.2e-10 40.8 0.0 0.00082 18.9 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CBY12389.1 - 7.7e-07 29.2 0.4 0.0088 16.3 0.0 3.6 2 2 1 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY12389.1 - 6.9e-05 22.7 0.1 0.066 13.2 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CBY12389.1 - 0.0093 15.9 0.1 3.9 7.6 0.0 2.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY12389.1 - 0.015 15.3 1.5 0.99 9.5 0.1 3.0 2 1 0 2 2 2 0 Galactose oxidase, central domain TSP_1 PF00090.19 CBY12390.1 - 4.4e-08 33.2 8.3 9.4e-08 32.2 8.3 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain WD40_alt PF14077.6 CBY12390.1 - 1.6 8.7 5.7 0.61 10.0 0.2 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif DNA_topoisoIV PF00521.20 CBY12390.1 - 4.5 6.0 12.3 7.9 5.2 12.3 1.3 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Phospholip_A2_1 PF00068.19 CBY12391.1 - 1e-09 38.9 6.7 1.3e-09 38.5 6.7 1.2 1 0 0 1 1 1 1 Phospholipase A2 DUF4710 PF15828.5 CBY12391.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Sec15 PF04091.12 CBY12392.1 - 0.11 11.9 0.4 0.13 11.6 0.4 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF1722 PF08349.11 CBY12393.1 - 0.1 12.9 2.7 0.19 12.0 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) FR47 PF08445.10 CBY12393.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein PI3K_P85_iSH2 PF16454.5 CBY12393.1 - 4.7 6.8 24.0 0.82 9.2 3.2 3.1 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_MLP1_2 PF07926.12 CBY12395.1 - 0.0076 16.3 21.1 0.0076 16.3 21.1 6.7 3 3 4 7 7 7 2 TPR/MLP1/MLP2-like protein Arena_ncap_C PF17290.2 CBY12395.1 - 0.028 13.8 0.5 0.063 12.6 0.5 1.5 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain Mce4_CUP1 PF11887.8 CBY12395.1 - 0.17 11.3 10.1 0.26 10.7 4.0 2.6 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Acyl-CoA_dh_2 PF08028.11 CBY12395.1 - 7.6 6.8 6.2 2.7 8.3 0.7 2.8 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Elicitin PF00964.17 CBY12398.1 - 0.019 15.1 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Elicitin Pkinase PF00069.25 CBY12399.1 - 5.6e-79 265.2 1.1 1.8e-46 158.7 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain CaMKII_AD PF08332.10 CBY12399.1 - 7.6e-37 126.3 0.0 1.7e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 CBY12399.1 - 1.7e-32 112.7 0.0 1.5e-16 60.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBY12399.1 - 7e-05 22.9 1.1 0.00083 19.3 1.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY12399.1 - 0.0039 16.0 1.9 0.0046 15.8 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase Mltc_N PF11873.8 CBY12399.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain SnoaL_3 PF13474.6 CBY12399.1 - 0.069 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain Imm48 PF15574.6 CBY12399.1 - 0.073 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 48 zf-C2H2 PF00096.26 CBY12400.1 - 0.019 15.4 19.8 0.036 14.5 5.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY12400.1 - 0.11 13.4 4.7 0.11 13.4 4.7 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger APP_Cu_bd PF12924.7 CBY12402.1 - 1.1e-18 67.7 3.5 1.6e-18 67.2 3.5 1.2 1 0 0 1 1 1 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.9 CBY12402.1 - 3.1e-12 46.8 0.1 5.6e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus TMEM51 PF15345.6 CBY12402.1 - 0.0028 17.5 0.0 0.0038 17.1 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 CcmD PF04995.14 CBY12402.1 - 7.5 6.7 7.8 7.6 6.7 6.5 1.7 1 1 1 2 2 2 0 Heme exporter protein D (CcmD) APP_N PF02177.16 CBY12403.1 - 3.7e-06 27.2 0.2 5e-06 26.8 0.2 1.1 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding DUF4996 PF16387.5 CBY12403.1 - 0.034 14.6 0.0 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function WH2 PF02205.20 CBY12406.1 - 8.6e-07 28.6 0.1 2.5e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 WH2 motif TRAM_LAG1_CLN8 PF03798.16 CBY12408.1 - 4.3e-18 65.8 9.4 4.3e-18 65.8 9.4 1.5 2 0 0 2 2 2 1 TLC domain Vut_1 PF02592.15 CBY12408.1 - 2.9 8.2 8.6 7.5 6.9 6.7 2.3 1 1 1 2 2 2 0 Putative vitamin uptake transporter SNF2_N PF00176.23 CBY12409.1 - 6.6e-48 163.2 0.4 3.5e-47 160.8 0.4 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY12409.1 - 2.6e-16 59.9 0.0 3.6e-15 56.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY12409.1 - 3.4e-11 43.4 0.0 1.7e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CBY12409.1 - 1.5e-05 24.3 0.3 6.2e-05 22.3 0.3 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.6 CBY12409.1 - 3.4e-05 22.9 0.0 6.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 CBY12409.1 - 4.3e-05 23.4 0.0 0.00013 21.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pkinase PF00069.25 CBY12410.1 - 7.8e-45 153.3 0.1 1.1e-44 152.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12410.1 - 9.6e-30 103.7 0.1 1.4e-29 103.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 CBY12410.1 - 5.7e-23 81.2 0.1 1.4e-22 80.0 0.0 1.7 2 0 0 2 2 1 1 C2 domain C1_1 PF00130.22 CBY12410.1 - 2.2e-15 56.3 15.8 1.7e-07 31.0 2.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CBY12410.1 - 8e-06 26.1 13.3 0.00043 20.5 2.5 2.5 2 0 0 2 2 2 2 C1 domain Zf_RING PF16744.5 CBY12410.1 - 3.3e-05 23.9 8.8 0.0067 16.5 0.5 2.9 2 0 0 2 2 2 2 KIAA1045 RING finger Pkinase_fungal PF17667.1 CBY12410.1 - 0.00049 19.0 0.0 0.00077 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY12410.1 - 0.016 14.1 0.1 0.025 13.5 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 CBY12410.1 - 0.046 13.7 12.0 0.068 13.1 1.4 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Kinase-like PF14531.6 CBY12410.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PTSIIA_gutA PF03829.13 CBY12410.1 - 0.11 12.3 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component Zn_ribbon_17 PF17120.5 CBY12410.1 - 0.17 11.5 11.8 1 9.0 4.5 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 CBY12410.1 - 0.56 10.1 19.4 2.5 8.1 7.4 3.0 2 1 1 3 3 3 0 PHD-finger zf-RING-like PF08746.11 CBY12410.1 - 1.5 9.2 17.3 0.36 11.2 2.6 2.8 2 1 0 2 2 2 0 RING-like domain FYVE PF01363.21 CBY12410.1 - 2.3 8.4 14.4 2.8 8.2 1.7 2.5 1 1 1 2 2 2 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 CBY12410.1 - 5.5 7.8 11.7 3.3 8.5 6.1 2.6 1 1 1 2 2 2 0 zinc-ribbon family DZR PF12773.7 CBY12410.1 - 6.5 6.9 12.7 3.5 7.7 2.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon PHD_4 PF16866.5 CBY12410.1 - 10 6.3 12.1 13 6.0 2.8 2.7 1 1 1 2 2 2 0 PHD-finger PfkB PF00294.24 CBY12411.1 - 2.5e-31 109.1 0.0 3.6e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Glyco_hydro_3_C PF01915.22 CBY12411.1 - 0.076 13.0 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain eIF-3c_N PF05470.12 CBY12411.1 - 0.67 8.2 6.9 1 7.6 6.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1980 PF09323.10 CBY12411.1 - 0.79 9.6 0.0 0.79 9.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Apt1 PF10351.9 CBY12411.1 - 2.4 6.9 6.9 3.2 6.5 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sulfotransfer_1 PF00685.27 CBY12412.1 - 2.5e-12 46.9 0.5 1.1e-11 44.7 0.5 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY12412.1 - 1.6e-07 31.9 0.3 0.069 13.5 0.0 3.2 1 1 1 3 3 3 3 Sulfotransferase family Calsequestrin PF01216.17 CBY12414.1 - 6.2e-89 298.7 5.9 7.8e-89 298.4 5.9 1.0 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.6 CBY12414.1 - 7e-11 42.4 4.2 2e-09 37.6 0.4 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 CBY12414.1 - 0.0025 17.8 0.0 0.77 9.8 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin ATP-grasp_6 PF18419.1 CBY12414.1 - 0.11 12.2 0.1 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp-like domain PS_Dcarbxylase PF02666.15 CBY12415.1 - 1.7e-43 148.6 0.0 1.8e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Glycos_transf_2 PF00535.26 CBY12416.1 - 3.5e-16 59.5 0.1 6.4e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Pkinase PF00069.25 CBY12417.1 - 7.8e-10 38.6 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12417.1 - 6.9e-07 28.8 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.6 CBY12417.1 - 0.19 11.9 3.2 8.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) BACK PF07707.15 CBY12418.1 - 1.4e-06 28.3 0.1 3.4e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 CBY12419.1 - 0.00012 22.3 4.3 0.2 12.0 0.3 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY12419.1 - 0.012 15.6 2.3 2.9 8.0 0.1 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY12419.1 - 0.037 13.6 12.9 1.5 8.4 1.8 4.3 4 1 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CBY12419.1 - 0.12 12.4 4.3 4.8 7.3 0.2 3.6 4 0 0 4 4 4 0 Kelch motif Sina PF03145.16 CBY12420.1 - 0.54 10.2 0.1 0.54 10.2 0.1 2.2 2 0 0 2 2 2 0 Seven in absentia protein family RVT_1 PF00078.27 CBY12421.1 - 7.7e-17 61.6 0.4 1.4e-16 60.7 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C4 PF00105.18 CBY12421.1 - 5e-15 55.7 10.4 1.3e-14 54.4 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) gag-asp_proteas PF13975.6 CBY12421.1 - 0.15 12.6 0.0 0.45 11.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-RRPl_C4 PF17026.5 CBY12421.1 - 0.38 10.9 5.1 0.49 10.5 3.8 1.9 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF4456 PF14644.6 CBY12422.1 - 8.4e-36 123.6 10.6 1.6e-35 122.7 10.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) GlutR_dimer PF00745.20 CBY12422.1 - 0.011 16.2 4.6 3.1 8.3 0.2 3.7 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain YmdB PF13277.6 CBY12422.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 YmdB-like protein Spore_III_AB PF09548.10 CBY12422.1 - 0.19 11.8 4.9 1.3 9.2 3.9 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Laminin_II PF06009.12 CBY12422.1 - 1.1 9.3 6.7 5.3 7.1 0.1 3.3 2 1 1 3 3 3 0 Laminin Domain II EF-hand_2 PF09068.11 CBY12422.1 - 3.2 7.9 5.9 1.5 8.9 2.7 2.0 2 1 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 CBY12423.1 - 1.7e-06 28.4 2.0 8.5e-06 26.1 0.7 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY12423.1 - 4.2e-06 26.5 1.9 2.8e-05 23.9 0.7 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY12423.1 - 8.6e-06 24.9 0.8 1.5e-05 24.2 0.3 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY12423.1 - 0.0001 21.9 0.7 0.0017 18.1 0.7 2.2 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBY12423.1 - 0.00015 21.1 0.4 0.00038 19.8 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.7 CBY12423.1 - 0.0054 16.7 0.2 0.0061 16.5 0.2 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand ORMDL PF04061.14 CBY12424.1 - 0.12 12.2 0.2 0.43 10.4 0.1 1.8 2 0 0 2 2 2 0 ORMDL family Neural_ProG_Cyt PF06567.11 CBY12424.1 - 0.4 10.9 0.0 0.4 10.9 0.0 3.0 3 1 0 3 3 3 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Phage_integrase PF00589.22 CBY12425.1 - 0.044 13.6 0.1 0.23 11.2 0.0 2.0 1 1 1 2 2 2 0 Phage integrase family MRP-63 PF14978.6 CBY12425.1 - 9.6 6.9 7.7 24 5.7 0.5 2.9 2 1 0 3 3 3 0 Mitochondrial ribosome protein 63 Alpha-mann_mid PF09261.11 CBY12426.1 - 0.04 14.0 0.3 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Alpha mannosidase middle domain Mt_ATP-synt_B PF05405.14 CBY12426.1 - 0.094 12.3 2.1 0.23 11.1 2.1 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SCVP PF17619.2 CBY12427.1 - 0.34 11.8 5.5 1.9 9.4 0.3 3.0 3 0 0 3 3 3 0 Secreted clade V proteins ESCRT-II PF05871.12 CBY12427.1 - 3.1 8.0 6.0 1.4 9.2 0.7 2.4 1 1 1 2 2 2 0 ESCRT-II complex subunit Dimer_Tnp_hAT PF05699.14 CBY12429.1 - 9.4e-10 38.2 0.2 1.3e-09 37.7 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HIM1 PF08732.10 CBY12429.1 - 0.0031 17.1 0.1 0.0042 16.6 0.1 1.3 1 1 0 1 1 1 1 HIM1 DUF3553 PF12073.8 CBY12430.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Fis1_TPR_C PF14853.6 CBY12430.1 - 0.15 12.2 0.2 0.98 9.5 0.2 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat zf-CCHC PF00098.23 CBY12430.1 - 0.39 10.9 1.4 0.78 9.9 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Astacin PF01400.24 CBY12432.1 - 2.9e-27 95.5 0.1 3.5e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY12432.1 - 3.7e-05 23.8 7.0 6.2e-05 23.1 7.0 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Abhydrolase_2 PF02230.16 CBY12433.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PLAT PF01477.23 CBY12434.1 - 2e-06 28.4 0.1 0.0062 17.1 0.0 2.1 2 0 0 2 2 2 2 PLAT/LH2 domain Rota_NSP3 PF01665.16 CBY12435.1 - 0.094 11.8 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Gln-synt_C PF00120.24 CBY12437.1 - 2.1e-17 63.1 0.0 5e-13 48.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CBY12437.1 - 3e-15 55.7 0.0 5.5e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain TGF_beta PF00019.20 CBY12438.1 - 1.3e-26 93.6 1.3 2.3e-26 92.8 1.3 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 CBY12438.1 - 6.6e-13 49.0 1.8 1.3e-12 48.1 0.0 2.0 1 1 1 2 2 2 1 TGF-beta propeptide SR-25 PF10500.9 CBY12438.1 - 0.0092 15.6 21.4 0.014 15.0 21.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CBY12438.1 - 0.55 8.9 3.3 0.76 8.5 3.3 1.1 1 0 0 1 1 1 0 Presenilin CCDC106 PF15794.5 CBY12438.1 - 1.4 8.6 13.9 2.7 7.7 13.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF3827 PF12877.7 CBY12438.1 - 2 6.7 9.9 2.9 6.1 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC45 PF02724.14 CBY12438.1 - 3.3 5.9 10.9 5.3 5.2 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 CBY12439.1 - 7.3e-44 150.1 0.0 2e-43 148.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12439.1 - 3.6e-29 101.8 0.0 9.9e-29 100.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase TBK1_CCD1 PF18394.1 CBY12439.1 - 5e-08 32.8 12.5 1.1e-07 31.6 10.8 2.3 1 1 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Pkinase_fungal PF17667.1 CBY12439.1 - 0.00091 18.1 0.3 0.002 17.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase DUF2407 PF10302.9 CBY12439.1 - 0.087 13.4 0.2 0.52 10.9 0.0 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain WD40 PF00400.32 CBY12440.1 - 2.4e-09 37.7 9.4 0.01 16.7 0.3 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY12440.1 - 0.0019 18.5 0.0 0.73 10.2 0.0 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain GbpA_2 PF18416.1 CBY12440.1 - 0.04 14.2 0.1 0.16 12.3 0.0 2.0 3 0 0 3 3 3 0 N-acetylglucosamine binding protein domain 2 Big_3 PF07523.12 CBY12440.1 - 0.27 11.6 0.9 1.8 8.9 0.0 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) CENP-H PF05837.12 CBY12441.1 - 0.015 15.7 3.0 0.015 15.7 3.0 11.0 2 2 9 11 11 11 0 Centromere protein H (CENP-H) Jagunal PF07086.12 CBY12442.1 - 5e-34 118.0 1.5 5.6e-34 117.8 1.5 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis FtsJ PF01728.19 CBY12443.1 - 5.9e-71 238.2 0.1 7.6e-71 237.9 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CBY12443.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CBY12443.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_24 PF13578.6 CBY12443.1 - 0.15 13.1 0.0 0.59 11.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CBY12443.1 - 0.18 11.1 0.1 0.49 9.7 0.1 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CBY12443.1 - 0.18 12.6 0.0 1.1 9.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain CRM1_C PF08767.11 CBY12444.1 - 0.006 15.8 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 CRM1 C terminal Peptidase_S49 PF01343.18 CBY12444.1 - 0.12 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 Ribosomal_L22 PF00237.19 CBY12444.1 - 0.15 12.4 0.0 3.3 8.0 0.0 3.1 3 1 0 3 3 3 0 Ribosomal protein L22p/L17e DB PF01682.19 CBY12445.1 - 0.27 11.5 4.6 0.18 12.1 1.5 2.1 2 0 0 2 2 2 0 DB module LisH PF08513.11 CBY12446.1 - 0.014 15.4 0.1 0.045 13.7 0.1 2.0 1 0 0 1 1 1 0 LisH zf-C2H2_8 PF15909.5 CBY12446.1 - 0.038 14.3 11.3 0.023 15.0 8.7 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 CBY12446.1 - 0.84 9.4 18.4 3.3 7.6 2.0 4.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain PX PF00787.24 CBY12447.1 - 1.5e-05 24.9 2.9 2.8e-05 24.1 2.9 1.4 1 0 0 1 1 1 1 PX domain PIN_5 PF08745.11 CBY12447.1 - 0.13 11.7 0.3 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 PINc domain ribonuclease Thioredoxin PF00085.20 CBY12448.1 - 1.2e-19 70.2 0.0 2.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.17 CBY12448.1 - 5.4e-10 38.9 1.2 6.8e-10 38.5 1.2 1.0 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.6 CBY12448.1 - 2e-07 31.1 0.4 0.018 14.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY12448.1 - 3.2e-06 27.5 0.1 6.3e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBY12448.1 - 4.4e-05 23.0 0.2 6.4e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBY12448.1 - 0.0024 18.1 0.4 0.033 14.5 0.2 2.5 1 1 0 1 1 1 1 Thioredoxin-like DUF4905 PF16248.5 CBY12448.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) Thioredoxin_7 PF13899.6 CBY12448.1 - 0.053 13.7 0.4 0.84 9.9 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin-like HyaE PF07449.11 CBY12448.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE RA PF00788.23 CBY12449.1 - 2.1e-11 44.3 0.1 6.2e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 CBY12449.1 - 0.012 15.5 3.6 0.021 14.7 3.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CBY12449.1 - 0.015 15.6 2.0 0.043 14.1 2.0 1.8 1 0 0 1 1 1 0 C1 domain Stap_Strp_tox_C PF02876.17 CBY12449.1 - 0.14 12.4 1.4 2.1 8.7 0.0 2.7 3 0 0 3 3 3 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Pcc1 PF09341.10 CBY12450.1 - 6e-18 64.8 0.2 6e-18 64.8 0.2 2.6 3 0 0 3 3 3 1 Transcription factor Pcc1 Sec5 PF15469.6 CBY12450.1 - 1.3e-12 47.9 1.9 1.3e-12 47.9 1.9 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Erf4 PF10256.9 CBY12450.1 - 0.15 12.2 0.4 30 4.7 0.0 2.8 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUF2408 PF10303.9 CBY12450.1 - 0.46 11.0 6.0 0.53 10.9 2.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2408) Pkinase_Tyr PF07714.17 CBY12451.1 - 3.1e-05 23.4 0.1 4.2e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Aminotran_1_2 PF00155.21 CBY12453.1 - 1.3e-49 169.3 0.0 2.1e-49 168.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CBY12453.1 - 0.00069 18.7 0.0 0.0015 17.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBY12453.1 - 0.0079 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CBY12453.1 - 0.017 13.7 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CBY12453.1 - 0.029 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family U-box PF04564.15 CBY12455.1 - 1.3e-08 34.9 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain DJ-1_PfpI PF01965.24 CBY12457.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family BAF250_C PF12031.8 CBY12458.1 - 0.052 12.8 0.1 0.066 12.5 0.1 1.1 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa DUF5345 PF17280.2 CBY12458.1 - 0.12 12.3 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) EGF_CA PF07645.15 CBY12461.1 - 7.1e-42 141.3 97.9 8.4e-09 35.5 10.1 7.7 8 0 0 8 8 8 7 Calcium-binding EGF domain cEGF PF12662.7 CBY12461.1 - 1.6e-25 88.7 38.9 1.4e-08 34.4 0.6 7.6 7 0 0 7 7 7 5 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY12461.1 - 1.1e-18 67.1 80.7 9.3e-05 22.5 8.1 8.0 7 0 0 7 7 7 6 EGF domain FXa_inhibition PF14670.6 CBY12461.1 - 6.1e-17 61.6 90.8 3.1e-09 36.9 9.1 7.7 7 0 0 7 7 7 6 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY12461.1 - 4.2e-14 52.5 79.9 0.00011 22.4 7.9 7.7 8 0 0 8 8 8 5 EGF-like domain hEGF PF12661.7 CBY12461.1 - 3e-10 40.3 69.3 0.0011 19.5 4.6 7.8 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY12461.1 - 5.4e-06 26.3 20.5 9.1e-05 22.4 7.2 6.8 7 0 0 7 7 7 3 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY12461.1 - 0.00013 22.2 5.4 0.00013 22.2 5.4 7.9 6 2 2 8 8 8 5 Pvs28 EGF domain EGF_2 PF07974.13 CBY12461.1 - 0.033 14.5 7.2 0.033 14.5 7.2 7.5 8 0 0 8 8 8 0 EGF-like domain Mucin PF01456.17 CBY12461.1 - 0.5 10.3 17.0 0.98 9.4 17.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSF PF00474.17 CBY12462.1 - 2.1e-125 418.8 16.5 3.3e-125 418.1 16.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family EGF PF00008.27 CBY12463.1 - 1.1e-05 25.7 6.4 2.1e-05 24.7 6.4 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 CBY12463.1 - 0.012 15.9 9.1 0.038 14.3 9.1 1.9 1 0 0 1 1 1 0 EGF-like domain Kelch_2 PF07646.15 CBY12463.1 - 0.15 12.1 1.1 2.7 8.1 0.0 3.1 3 0 0 3 3 3 0 Kelch motif hEGF PF12661.7 CBY12463.1 - 2.9 8.7 5.7 7.8 7.3 5.7 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF Kelch_5 PF13854.6 CBY12465.1 - 0.0076 16.2 1.0 0.094 12.7 0.0 3.2 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY12465.1 - 0.061 13.6 0.1 10 6.6 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY12466.1 - 0.0048 16.9 3.1 0.0059 16.6 0.0 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CBY12466.1 - 0.04 13.9 0.2 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 CBY12466.1 - 0.12 12.7 0.2 21 5.6 0.0 2.5 2 0 0 2 2 2 0 Kelch motif DUF3450 PF11932.8 CBY12467.1 - 0.26 10.6 6.9 0.48 9.7 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) E2F_CC-MB PF16421.5 CBY12467.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.8 1 1 2 3 3 3 0 E2F transcription factor CC-MB domain UPF0242 PF06785.11 CBY12467.1 - 0.72 9.9 17.5 1.1 9.4 17.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CBY12469.1 - 0.04 14.5 5.0 1.4 9.6 0.7 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Kelch_6 PF13964.6 CBY12469.1 - 0.052 13.9 2.8 2.8 8.4 0.0 4.0 3 2 1 4 4 4 0 Kelch motif Kelch_4 PF13418.6 CBY12469.1 - 0.1 12.6 0.5 37 4.4 0.3 3.3 2 1 0 2 2 2 0 Galactose oxidase, central domain DUF2681 PF10883.8 CBY12469.1 - 0.12 12.8 0.1 0.48 10.9 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) GH114_assoc PF14741.6 CBY12469.1 - 0.17 12.1 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain LapA_dom PF06305.11 CBY12469.1 - 1.3 8.9 3.2 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain EGF_CA PF07645.15 CBY12470.1 - 3.3e-55 184.0 125.7 4.1e-10 39.7 10.1 8.2 8 0 0 8 8 8 8 Calcium-binding EGF domain EGF_3 PF12947.7 CBY12470.1 - 3.4e-26 91.1 99.0 2.7e-08 33.8 6.0 9.6 7 2 3 10 10 10 7 EGF domain cEGF PF12662.7 CBY12470.1 - 6.1e-23 80.4 67.4 7.4e-05 22.6 3.4 8.9 8 0 0 8 8 8 7 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY12470.1 - 5.4e-15 55.4 88.3 9.7e-05 22.6 5.2 8.9 6 2 2 8 8 8 6 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY12470.1 - 9.8e-14 51.3 83.1 0.00018 21.7 5.5 9.5 8 2 0 8 8 8 7 EGF-like domain EGF_MSP1_1 PF12946.7 CBY12470.1 - 2.2e-08 34.0 36.4 0.00016 21.7 4.2 8.0 8 2 0 8 8 8 5 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY12470.1 - 7.3e-07 29.4 24.2 4.4e-05 23.7 9.2 8.4 6 2 0 7 7 7 4 Pvs28 EGF domain hEGF PF12661.7 CBY12470.1 - 0.00012 22.6 12.6 0.00071 20.1 1.9 11.5 11 1 1 12 12 12 6 Human growth factor-like EGF Prenyltrans PF00432.21 CBY12470.1 - 2.7 7.8 8.5 11 5.8 0.0 4.5 5 1 0 5 5 5 0 Prenyltransferase and squalene oxidase repeat Kelch_5 PF13854.6 CBY12471.1 - 2.4e-05 24.2 0.5 0.0023 17.9 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY12471.1 - 0.0012 19.1 2.9 0.59 10.5 0.0 4.4 4 2 1 5 5 5 1 Kelch motif Kelch_4 PF13418.6 CBY12471.1 - 0.014 15.3 0.3 5.2 7.2 0.1 3.0 2 1 0 2 2 2 0 Galactose oxidase, central domain APC_N_CC PF16689.5 CBY12471.1 - 0.12 12.5 0.5 0.27 11.3 0.5 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Kelch_1 PF01344.25 CBY12471.1 - 0.12 11.9 0.0 4 7.1 0.0 2.7 2 0 0 2 2 2 0 Kelch motif CUB PF00431.20 CBY12472.1 - 4.9e-12 46.2 0.4 5e-10 39.7 0.1 2.6 2 1 1 3 3 3 2 CUB domain FXa_inhibition PF14670.6 CBY12472.1 - 0.0011 19.2 11.7 0.0048 17.2 11.7 2.2 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site COesterase PF00135.28 CBY12473.1 - 4.1e-76 256.9 0.1 5.1e-76 256.6 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY12473.1 - 5.2e-07 29.7 0.7 4.7e-06 26.6 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chorein_N PF12624.7 CBY12474.1 - 1.9e-29 102.1 2.7 3.7e-29 101.2 0.3 2.4 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CBY12474.1 - 1.7e-07 31.3 0.3 1.4e-06 28.3 0.3 2.2 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal AMP-binding PF00501.28 CBY12475.1 - 3.5e-85 286.2 0.0 4.2e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY12475.1 - 1.1e-19 71.2 0.0 1.3e-18 67.8 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CBY12475.1 - 1e-17 63.8 1.1 1e-17 63.8 1.1 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus ABC_membrane PF00664.23 CBY12476.1 - 0.00079 19.2 3.2 0.0025 17.5 3.2 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 CBY12477.1 - 1.3e-94 316.9 21.5 1.2e-53 182.5 11.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY12477.1 - 2.5e-68 228.8 0.0 8.3e-34 117.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBY12477.1 - 6e-17 61.8 0.2 9.6e-07 28.5 0.1 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CBY12477.1 - 2.1e-09 37.8 0.5 0.0011 19.3 0.0 3.4 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CBY12477.1 - 1.5e-08 34.7 0.2 0.0054 16.6 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 CBY12477.1 - 8.5e-08 32.3 0.0 0.0023 17.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CBY12477.1 - 4.2e-07 29.1 0.2 0.025 13.4 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 CBY12477.1 - 2e-05 25.0 3.4 0.021 15.2 0.1 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CBY12477.1 - 3.9e-05 23.3 0.5 0.33 10.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 CBY12477.1 - 4.1e-05 23.7 3.6 0.57 10.4 0.2 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CBY12477.1 - 5.6e-05 22.5 0.1 0.41 9.9 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin Rad17 PF03215.15 CBY12477.1 - 0.00017 21.6 0.4 0.8 9.6 0.1 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_30 PF13604.6 CBY12477.1 - 0.00027 20.7 1.1 0.57 9.9 0.1 3.6 3 1 0 3 3 3 2 AAA domain G-alpha PF00503.20 CBY12477.1 - 0.00027 20.2 0.3 0.61 9.2 0.0 2.4 3 0 0 3 3 3 2 G-protein alpha subunit AAA PF00004.29 CBY12477.1 - 0.00084 19.8 2.0 3.1 8.2 0.3 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBY12477.1 - 0.0026 17.3 0.3 0.4 10.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 CBY12477.1 - 0.0027 17.7 0.7 1.4 8.9 0.0 3.9 5 0 0 5 5 5 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CBY12477.1 - 0.0038 16.8 0.1 3.7 7.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain PRK PF00485.18 CBY12477.1 - 0.0041 16.9 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CBY12477.1 - 0.007 16.7 0.5 5.5 7.4 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_21 PF13304.6 CBY12477.1 - 0.011 15.5 0.2 5.4 6.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CBY12477.1 - 0.016 15.8 0.0 3.9 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CBY12477.1 - 0.03 14.0 0.2 7.9 6.1 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Peptidase_U40 PF10464.9 CBY12477.1 - 0.038 13.7 0.2 0.086 12.5 0.2 1.5 1 0 0 1 1 1 0 Peptidase U40 DUF815 PF05673.13 CBY12477.1 - 0.043 13.0 0.0 3.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.7 CBY12477.1 - 0.052 12.5 0.0 3.5 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.22 CBY12477.1 - 0.091 11.9 1.3 12 5.0 0.3 2.9 2 1 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 CBY12477.1 - 0.16 11.7 0.1 14 5.4 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 CBY12477.1 - 0.16 12.1 0.1 16 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain FAP PF07174.11 CBY12477.1 - 0.18 11.2 0.0 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) PQQ PF01011.21 CBY12478.1 - 1.5e-06 27.8 0.2 3.5e-05 23.5 0.2 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.6 CBY12478.1 - 0.00084 19.0 0.2 0.0058 16.2 0.1 2.3 2 1 0 2 2 2 1 PQQ-like domain VPS13_C PF16909.5 CBY12479.1 - 3.3e-22 79.1 1.4 2.1e-21 76.5 0.1 2.3 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal eIF-5_eIF-2B PF01873.17 CBY12479.1 - 0.014 15.3 0.1 0.75 9.7 0.0 2.3 1 1 1 2 2 2 0 Domain found in IF2B/IF5 DUF1757 PF08560.10 CBY12479.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) SHR-BD PF06650.12 CBY12480.1 - 1.3e-06 28.0 1.1 0.018 14.4 0.1 4.1 3 1 1 4 4 4 4 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 CBY12481.1 - 5.7e-13 49.0 0.9 2.5e-12 46.9 0.0 2.4 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CBY12481.1 - 5.6e-07 29.6 0.4 3.1e-06 27.2 0.4 2.1 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Pkinase_Tyr PF07714.17 CBY12483.1 - 3.8e-60 203.4 0.0 5.7e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY12483.1 - 1.5e-52 178.6 0.0 3.6e-52 177.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY12483.1 - 0.027 13.3 0.2 0.069 11.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase DUF5339 PF17274.2 CBY12483.1 - 0.054 14.3 1.2 0.15 13.0 1.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5339) HA PF03457.14 CBY12483.1 - 0.1 12.9 1.0 0.34 11.3 1.0 1.9 1 0 0 1 1 1 0 Helicase associated domain SseC PF04888.12 CBY12483.1 - 5.6 6.5 5.1 10 5.6 5.1 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family zf-C2H2_10 PF16588.5 CBY12484.1 - 0.0048 16.6 1.1 0.015 15.0 1.1 1.9 1 0 0 1 1 1 1 C2H2 zinc-finger Glucosaminidase PF01832.20 CBY12484.1 - 0.065 13.7 0.0 8 7.0 0.0 2.4 2 1 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 7tm_1 PF00001.21 CBY12485.1 - 1.4e-12 47.5 4.0 1.4e-12 47.5 4.0 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF1774 PF08611.10 CBY12485.1 - 0.0018 18.6 1.4 0.0021 18.3 1.4 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1774) 7TM_GPCR_Srsx PF10320.9 CBY12485.1 - 0.0023 17.4 5.9 0.0052 16.2 5.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CBY12486.1 - 4.8e-12 45.8 0.1 4.9e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SIX1_SD PF16878.5 CBY12487.1 - 1.8e-41 141.1 0.1 3e-40 137.2 0.0 2.4 3 0 0 3 3 3 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CBY12487.1 - 5.4e-13 48.6 0.8 1.2e-12 47.5 0.8 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY12487.1 - 6.5e-10 38.8 2.0 1.9e-09 37.3 0.7 2.3 2 0 0 2 2 2 1 Homeobox KN domain Phage_mat-A PF03863.13 CBY12487.1 - 0.12 11.2 0.2 0.19 10.6 0.2 1.2 1 0 0 1 1 1 0 Phage maturation protein Kelch_1 PF01344.25 CBY12488.1 - 0.017 14.7 0.1 0.046 13.3 0.1 1.8 1 0 0 1 1 1 0 Kelch motif BTB_2 PF02214.22 CBY12490.1 - 2.2e-13 50.3 0.0 7.1e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Mating_N PF12731.7 CBY12490.1 - 0.18 11.9 2.0 2.2 8.4 0.1 2.6 2 1 1 3 3 3 0 Mating-type protein beta 1 Ephrin_rec_like PF07699.13 CBY12491.1 - 4.7e-06 26.3 29.6 7.2e-05 22.5 2.8 91.8 71 19 20 94 94 94 64 Putative ephrin-receptor like Serinc PF03348.15 CBY12492.1 - 4.5e-18 65.4 9.7 2.5e-12 46.5 5.1 2.1 2 0 0 2 2 2 2 Serine incorporator (Serinc) ASFV_L11L PF05293.11 CBY12492.1 - 0.0068 16.7 2.7 0.015 15.6 2.2 1.8 1 1 0 1 1 1 1 African swine fever virus (ASFV) L11L protein MCM_bind PF09739.9 CBY12493.1 - 8e-25 87.3 0.4 9e-25 87.2 0.4 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 CBY12493.1 - 0.045 14.2 0.3 0.078 13.4 0.3 1.4 1 0 0 1 1 1 0 MCM AAA-lid domain Bt_P21 PF05560.11 CBY12493.1 - 0.086 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein WD40 PF00400.32 CBY12494.1 - 0.56 11.2 4.0 1.5e+02 3.5 0.0 4.6 4 1 0 4 4 4 0 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CBY12495.1 - 7.7e-90 302.1 0.3 7.7e-90 302.1 0.3 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 CBY12495.1 - 1e-42 143.3 17.5 2.1e-08 34.7 0.3 8.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY12495.1 - 5.1e-15 55.5 0.4 1.1e-06 28.8 0.0 5.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY12495.1 - 0.014 15.3 0.6 11 5.8 0.1 3.9 3 2 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CBY12495.1 - 0.046 12.4 0.1 0.046 12.4 0.1 3.9 1 1 3 4 4 4 0 Nucleoporin Nup120/160 PPI_Ypi1 PF07491.11 CBY12495.1 - 0.16 11.8 0.4 0.43 10.4 0.4 1.7 1 0 0 1 1 1 0 Protein phosphatase inhibitor KTI12 PF08433.10 CBY12496.1 - 5.2e-62 209.8 0.0 6.3e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CBY12496.1 - 2.6e-09 37.4 0.0 5.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY12496.1 - 0.032 14.8 0.0 0.073 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.31 CBY12498.1 - 4.4e-13 49.1 0.9 9.9e-13 48.0 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain Dak1 PF02733.17 CBY12499.1 - 4.7e-94 314.8 0.1 7.2e-94 314.2 0.1 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CBY12499.1 - 3.5e-38 131.2 1.5 6.2e-38 130.4 1.5 1.4 1 0 0 1 1 1 1 DAK2 domain bZIP_1 PF00170.21 CBY12500.1 - 2.6e-08 33.8 22.6 5.6e-08 32.8 22.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CBY12500.1 - 0.00026 21.4 14.7 0.00026 21.4 14.7 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CBY12500.1 - 0.0003 20.8 15.5 0.0003 20.8 15.5 2.4 1 1 1 2 2 2 1 Basic region leucine zipper Asp_protease_2 PF13650.6 CBY12502.1 - 0.00012 22.6 0.0 0.00026 21.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY12502.1 - 0.00084 19.8 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CBY12502.1 - 0.0026 17.7 3.9 0.0061 16.6 3.9 1.6 1 0 0 1 1 1 1 Zinc knuckle RSRP PF17069.5 CBY12502.1 - 0.026 14.1 41.5 0.048 13.2 41.5 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 RVP_2 PF08284.11 CBY12502.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease SBP_bac_3 PF00497.20 CBY12502.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF3456 PF11938.8 CBY12503.1 - 0.011 16.2 0.4 0.017 15.6 0.4 1.3 1 1 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP PHA_gran_rgn PF09650.10 CBY12503.1 - 0.044 14.1 0.1 0.086 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) PET10 PF17316.2 CBY12503.1 - 0.094 12.2 0.5 0.13 11.8 0.5 1.2 1 0 0 1 1 1 0 Petite colonies protein 10 Gly_rich PF12810.7 CBY12505.1 - 9.8e-06 25.7 32.7 2.4e-05 24.4 32.7 1.6 1 0 0 1 1 1 1 Glycine rich protein zf-C2H2_4 PF13894.6 CBY12506.1 - 8e-22 76.1 76.6 0.0034 18.1 0.6 11.5 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY12506.1 - 5.2e-18 64.4 87.1 0.018 15.5 0.6 11.5 11 1 0 11 11 11 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY12506.1 - 1e-13 51.0 81.8 2.5e-06 27.6 0.8 11.2 12 0 0 12 12 12 6 Zinc-finger double domain zf-C2H2_8 PF15909.5 CBY12506.1 - 0.00012 22.3 42.1 0.0053 17.0 8.3 5.0 2 1 2 5 5 5 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CBY12506.1 - 0.00015 22.0 64.7 0.0071 16.6 0.2 10.7 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY12506.1 - 0.15 12.4 61.9 2.5 8.5 1.1 8.2 2 1 7 9 9 9 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CBY12506.1 - 0.96 10.1 49.4 2.2 9.0 4.2 8.1 2 1 5 7 7 7 0 Zinc finger C2H2-type, 3 repeats Rad50_zn_hook PF04423.14 CBY12506.1 - 1.1 9.1 9.0 0.72 9.7 0.1 4.1 4 0 0 4 4 4 0 Rad50 zinc hook motif PI3_PI4_kinase PF00454.27 CBY12508.1 - 4.8e-22 79.0 0.7 8.9e-20 71.5 0.7 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CBY12508.1 - 0.0029 17.0 0.1 0.05 13.0 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CBY12508.1 - 0.038 13.3 0.0 0.12 11.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4135) SNF PF00209.18 CBY12509.1 - 6.7e-138 460.6 32.3 9.6e-138 460.1 32.3 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family INSIG PF07281.12 CBY12509.1 - 0.0072 16.0 1.7 4.1 7.0 0.2 3.1 2 1 0 2 2 2 2 Insulin-induced protein (INSIG) DUF4505 PF14956.6 CBY12511.1 - 7.6e-32 110.5 2.8 8.9e-32 110.3 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) HEAT PF02985.22 CBY12512.1 - 0.35 11.2 4.8 10 6.7 0.0 5.2 7 0 0 7 7 7 0 HEAT repeat AAA_34 PF13872.6 CBY12513.1 - 1.7e-131 437.6 0.0 2.3e-131 437.2 0.0 1.1 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 CBY12513.1 - 9.9e-07 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 CBY12513.1 - 6.6e-05 23.0 0.0 0.00019 21.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDPS PF16715.5 CBY12513.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Cyclodipeptide synthase DUF4985 PF16373.5 CBY12513.1 - 0.12 12.9 1.4 3.9 8.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function Tau95 PF09734.9 CBY12517.1 - 0.18 12.6 2.3 0.26 12.1 0.1 2.3 2 1 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DnaJ PF00226.31 CBY12518.1 - 2.9e-13 49.7 1.5 2.9e-13 49.7 1.5 2.2 1 1 1 2 2 2 1 DnaJ domain OTU PF02338.19 CBY12521.1 - 4.7e-10 40.0 0.2 1.2e-09 38.7 0.2 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease NST1 PF13945.6 CBY12521.1 - 0.73 9.9 14.1 3.1 7.9 1.2 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Tropomodulin PF03250.14 CBY12523.1 - 1.7e-32 112.4 1.7 3.4e-32 111.4 1.7 1.4 1 0 0 1 1 1 1 Tropomodulin IL13 PF03487.13 CBY12524.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Interleukin-13 DUF4660 PF15559.6 CBY12524.1 - 0.11 12.9 0.5 0.23 11.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) MMS22L_C PF14911.6 CBY12524.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal 4F5 PF04419.14 CBY12526.1 - 4e-09 37.2 6.9 4e-09 37.2 6.9 2.2 2 0 0 2 2 2 1 4F5 protein family Erv26 PF04148.13 CBY12528.1 - 3.3e-52 177.3 14.3 1.4e-51 175.2 14.3 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF373 PF04123.13 CBY12528.1 - 0.71 9.3 5.5 1 8.8 5.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DnaJ_C PF01556.18 CBY12529.1 - 3.9e-32 111.4 0.0 5.3e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBY12529.1 - 3e-21 75.3 2.2 5.5e-21 74.5 2.2 1.5 1 0 0 1 1 1 1 DnaJ domain BCIP PF13862.6 CBY12530.1 - 5.4e-21 75.3 0.7 8.2e-21 74.7 0.7 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein VMA21 PF09446.10 CBY12531.1 - 4.6e-06 26.6 11.3 1.3e-05 25.2 11.3 1.6 1 1 0 1 1 1 1 VMA21-like domain DUF3007 PF11460.8 CBY12531.1 - 0.016 15.5 0.9 0.019 15.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF1616 PF07760.11 CBY12531.1 - 0.087 12.2 2.3 0.1 12.0 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Syndecan PF01034.20 CBY12531.1 - 4.4 7.3 6.3 1.5 8.8 3.3 1.7 1 1 1 2 2 2 0 Syndecan domain Vps35 PF03635.17 CBY12532.1 - 2.7e-201 670.9 7.9 3.2e-201 670.7 7.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 HVSL PF09749.9 CBY12532.1 - 0.012 15.1 4.8 0.023 14.2 4.8 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein Chalcone_2 PF16035.5 CBY12532.1 - 0.1 12.4 2.3 0.47 10.2 2.2 2.2 2 0 0 2 2 2 0 Chalcone isomerase like IFT20 PF14931.6 CBY12533.1 - 5.8e-31 107.1 9.6 6.5e-31 107.0 9.6 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 JIP_LZII PF16471.5 CBY12533.1 - 1.1 9.4 10.6 0.3 11.3 5.2 2.2 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II NodZ PF05830.11 CBY12534.1 - 0.043 12.6 0.0 0.083 11.7 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Mannosyl_trans2 PF04188.13 CBY12535.1 - 1e-28 100.9 6.8 1.3e-28 100.6 6.8 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) GT87 PF09594.10 CBY12535.1 - 0.0079 15.9 5.8 0.013 15.3 5.8 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 87 DnaJ_C PF01556.18 CBY12536.1 - 5e-35 120.8 0.1 7.6e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBY12536.1 - 4.8e-21 74.7 2.5 8.6e-21 73.8 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain WD40_like PF17005.5 CBY12537.1 - 0.066 12.5 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 CBY12539.1 - 6.5e-19 67.9 16.4 0.014 16.3 0.1 7.8 8 0 0 8 8 7 5 WD domain, G-beta repeat zf-C3HC4_4 PF15227.6 CBY12539.1 - 6.8e-05 22.9 5.2 0.00023 21.3 5.2 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-TRAF PF02176.18 CBY12539.1 - 9.1e-05 23.1 6.7 9.1e-05 23.1 6.7 2.2 2 0 0 2 2 1 1 TRAF-type zinc finger zf-RING_UBOX PF13445.6 CBY12539.1 - 9.9e-05 22.3 6.0 0.00029 20.8 6.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY12539.1 - 0.00011 22.0 3.1 0.00045 20.0 3.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PQQ_3 PF13570.6 CBY12539.1 - 0.00021 21.7 0.0 1.9 9.1 0.0 4.4 4 0 0 4 4 4 1 PQQ-like domain WD40_like PF17005.5 CBY12539.1 - 0.0017 17.7 0.5 0.076 12.3 0.4 2.5 1 1 1 2 2 2 1 WD40-like domain zf-C3HC4_3 PF13920.6 CBY12539.1 - 0.0021 17.9 6.5 0.0055 16.5 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY12539.1 - 0.0052 16.6 7.7 0.02 14.8 7.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY12539.1 - 0.019 14.9 8.6 0.057 13.4 8.6 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Nup160 PF11715.8 CBY12539.1 - 0.035 12.7 3.0 0.17 10.5 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF2046 PF09755.9 CBY12539.1 - 0.069 12.4 1.0 0.086 12.0 0.2 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Sina PF03145.16 CBY12539.1 - 0.23 11.4 15.8 0.41 10.6 2.6 2.8 2 1 1 3 3 3 0 Seven in absentia protein family zf-RING_6 PF14835.6 CBY12539.1 - 0.44 10.4 5.4 1.5 8.7 5.4 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY12539.1 - 4 7.4 17.6 0.041 13.7 8.6 2.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CBY12539.1 - 9.6 6.4 12.6 0.21 11.7 5.0 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 BOFC_N PF08977.10 CBY12540.1 - 0.098 12.7 0.5 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Bypass of Forespore C, N terminal Peptidase_M14 PF00246.24 CBY12541.1 - 7e-62 209.8 0.0 8.6e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase PACT_coil_coil PF10495.9 CBY12543.1 - 0.00075 20.0 1.8 0.0014 19.2 1.8 1.5 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Prophage_tail PF06605.11 CBY12543.1 - 0.11 11.7 0.1 0.12 11.6 0.1 1.0 1 0 0 1 1 1 0 Prophage endopeptidase tail DnaJ PF00226.31 CBY12544.1 - 1.6e-08 34.5 0.1 0.0088 16.2 0.0 3.2 2 1 1 3 3 3 2 DnaJ domain F-box PF00646.33 CBY12544.1 - 0.00044 20.1 0.3 0.0021 17.9 0.2 2.0 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 CBY12544.1 - 0.0011 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like RPT PF13446.6 CBY12544.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein YscO PF07321.12 CBY12546.1 - 0.013 15.5 7.0 0.013 15.5 7.0 1.6 2 0 0 2 2 2 0 Type III secretion protein YscO DUF1963 PF09234.10 CBY12546.1 - 0.059 13.8 1.7 0.073 13.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) T3SSipB PF16535.5 CBY12546.1 - 0.072 13.6 4.5 0.089 13.3 4.5 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB Cupin_8 PF13621.6 CBY12546.1 - 0.12 12.1 3.2 0.14 11.9 3.2 1.2 1 0 0 1 1 1 0 Cupin-like domain DUF4407 PF14362.6 CBY12546.1 - 0.2 11.0 3.0 0.22 10.9 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RbsD_FucU PF05025.13 CBY12546.1 - 0.24 11.8 2.4 0.24 11.8 1.4 1.5 1 1 1 2 2 2 0 RbsD / FucU transport protein family GNAT_acetyltr_2 PF13718.6 CBY12546.1 - 0.36 10.2 3.6 0.45 9.9 3.6 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 TPR_MLP1_2 PF07926.12 CBY12546.1 - 0.43 10.6 22.3 0.81 9.8 17.3 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 CBY12546.1 - 0.45 10.6 17.8 0.044 13.9 13.1 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 CBY12546.1 - 2 6.2 8.7 2.3 6.0 8.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CREPT PF16566.5 CBY12546.1 - 2.6 8.2 11.1 1.5 9.0 8.8 1.8 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Exonuc_VII_L PF02601.15 CBY12546.1 - 5.5 6.5 8.9 6.2 6.3 8.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 CBY12547.1 - 2.5e-45 154.9 0.0 2.9e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12547.1 - 5.9e-20 71.6 0.1 6.5e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 CBY12549.1 - 3.7e-08 33.4 0.3 0.0073 16.4 0.0 2.7 2 1 1 3 3 3 2 DnaJ domain F-box-like PF12937.7 CBY12549.1 - 0.00027 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY12549.1 - 0.00028 20.7 0.2 0.0059 16.5 0.2 2.3 1 1 0 1 1 1 1 F-box domain UxaE PF16257.5 CBY12549.1 - 0.04 12.6 0.6 0.055 12.1 0.6 1.2 1 0 0 1 1 1 0 tagaturonate epimerase RPT PF13446.6 CBY12549.1 - 0.094 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein SYCP2_ARLD PF18581.1 CBY12549.1 - 0.17 11.8 2.3 0.21 11.6 0.5 2.0 3 0 0 3 3 3 0 Synaptonemal complex 2 armadillo-repeat-like domain Beach PF02138.18 CBY12550.1 - 4.1e-118 393.7 0.1 5.3e-118 393.4 0.1 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 CBY12550.1 - 2.8e-09 37.4 3.4 7.3e-05 23.5 0.0 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY12550.1 - 0.0051 17.1 0.0 0.018 15.3 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ZU5 PF00791.20 CBY12551.1 - 6e-12 45.8 0.2 1.3e-11 44.7 0.2 1.5 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.6 CBY12551.1 - 1.4e-11 44.9 0.0 4.3e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CBY12551.1 - 2.8e-09 36.9 0.0 5.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY12551.1 - 1.1e-07 32.1 0.0 3.4e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY12551.1 - 3.8e-06 27.0 0.0 7.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain TSP_1 PF00090.19 CBY12551.1 - 0.0002 21.5 7.3 0.0002 21.5 7.3 3.1 3 0 0 3 3 3 2 Thrombospondin type 1 domain C2-set_2 PF08205.12 CBY12551.1 - 0.0068 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CBY12551.1 - 0.014 15.0 0.1 0.072 12.7 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain UPA PF17217.3 CBY12551.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 UPA domain Pkinase PF00069.25 CBY12552.1 - 0.037 13.4 0.3 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain AdoMet_Synthase PF01941.19 CBY12553.1 - 0.15 10.8 0.3 0.19 10.5 0.3 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Homeodomain PF00046.29 CBY12554.1 - 1.1e-20 73.3 3.5 1.1e-20 73.3 3.5 2.4 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 CBY12554.1 - 0.073 13.0 1.4 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain EF-hand_7 PF13499.6 CBY12556.1 - 5.7e-17 61.9 7.9 1.9e-08 34.6 3.6 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY12556.1 - 7.8e-17 59.5 16.6 1.7e-08 33.4 1.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY12556.1 - 9.1e-15 54.2 11.4 3.9e-09 36.2 0.1 3.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CBY12556.1 - 3.8e-12 45.1 10.0 0.00036 20.2 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 CBY12556.1 - 5.6e-06 26.6 0.8 0.028 14.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBY12556.1 - 4.1e-05 23.5 8.2 0.00049 20.0 0.4 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 CBY12556.1 - 0.00017 21.0 11.9 0.0024 17.3 0.2 4.4 4 0 0 4 4 4 2 EF hand TerB PF05099.13 CBY12556.1 - 0.034 14.1 0.5 3.2 7.7 0.0 2.5 1 1 1 3 3 3 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 CBY12556.1 - 0.26 11.6 4.4 2.8 8.3 1.9 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UFC1 PF08694.11 CBY12557.1 - 2.1e-83 277.5 0.7 2.4e-83 277.3 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 CBY12557.1 - 0.08 13.2 0.0 0.095 13.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain ORC2 PF04084.14 CBY12558.1 - 8.8e-19 67.6 0.1 1e-18 67.4 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 WGG PF10273.9 CBY12559.1 - 1.7e-14 54.2 0.1 3.6e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF3381 PF11861.8 CBY12559.1 - 0.025 14.4 2.2 0.044 13.6 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PRMT5_TIM PF17285.2 CBY12559.1 - 0.099 11.8 0.6 0.88 8.7 0.1 2.1 2 0 0 2 2 2 0 PRMT5 TIM barrel domain Acetyltransf_1 PF00583.25 CBY12560.1 - 1.3e-13 51.2 0.1 1.7e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY12560.1 - 9e-11 41.8 0.2 1.3e-10 41.3 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY12560.1 - 2.1e-09 37.7 0.1 3.5e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY12560.1 - 0.00034 20.8 0.2 0.00048 20.3 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF22 PF01629.16 CBY12560.1 - 0.021 14.5 0.0 0.17 11.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF22 FR47 PF08445.10 CBY12560.1 - 0.038 13.9 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 CBY12560.1 - 0.064 13.4 0.1 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Inositol_P PF00459.25 CBY12561.1 - 7.1e-73 245.5 0.0 8.2e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family eIF2A PF08662.11 CBY12562.1 - 8.3e-35 120.4 0.5 4.9e-31 108.1 0.0 3.8 3 2 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CBY12562.1 - 2.2e-07 31.1 0.1 0.04 14.2 0.0 4.7 2 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 CBY12562.1 - 5e-05 23.0 0.1 0.00013 21.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 CBY12562.1 - 0.017 13.1 0.0 2.7 5.9 0.0 2.2 2 0 0 2 2 2 0 IKI3 family WD40 PF00400.32 CBY12562.1 - 0.095 13.6 8.6 19 6.3 0.1 5.5 5 1 1 6 6 6 0 WD domain, G-beta repeat FAD_binding_1 PF00667.20 CBY12563.1 - 2.4e-15 56.7 0.7 1.3e-13 51.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 CBY12563.1 - 1e-13 51.9 0.0 2.2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 CBY12563.1 - 2e-10 41.1 0.1 3.8e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_6 PF08030.12 CBY12563.1 - 0.0049 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain PRKCSH-like PF12999.7 CBY12564.1 - 1.6e-27 96.4 7.3 2.8e-27 95.6 7.3 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CBY12564.1 - 1.4e-09 37.8 0.0 2.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 CBY12564.1 - 0.2 11.9 19.3 0.41 10.9 5.8 2.5 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A SPT16 PF08644.11 CBY12567.1 - 5.5e-52 176.0 3.0 1.6e-51 174.5 0.0 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 CBY12567.1 - 3.8e-31 108.4 0.0 1.2e-30 106.8 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 Rtt106 PF08512.12 CBY12567.1 - 2.1e-17 63.3 0.1 5.9e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like FACT-Spt16_Nlob PF14826.6 CBY12567.1 - 6.2e-09 35.9 0.2 2e-08 34.2 0.2 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain RdRP PF05183.12 CBY12568.1 - 5e-30 104.7 0.1 3.9e-27 95.2 0.0 2.0 2 0 0 2 2 2 2 RNA dependent RNA polymerase Peptidase_S24 PF00717.23 CBY12569.1 - 3.1e-05 23.8 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CBY12569.1 - 3.7e-05 23.5 0.0 0.00052 19.8 0.0 2.2 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Pkinase_Tyr PF07714.17 CBY12570.1 - 9.4e-39 133.2 0.0 1.2e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY12570.1 - 6.2e-14 52.0 0.0 8.8e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY12570.1 - 0.037 13.3 0.2 0.83 8.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase_Tyr PF07714.17 CBY12571.1 - 1.4e-27 96.6 0.0 2.9e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY12571.1 - 3.1e-12 46.4 0.0 5.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF267 PF03268.14 CBY12571.1 - 0.0026 16.7 0.3 0.0037 16.2 0.3 1.2 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF267 DUF2207 PF09972.9 CBY12571.1 - 0.033 13.0 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATP11 PF06644.11 CBY12572.1 - 1.1e-34 120.5 0.3 1.3e-34 120.3 0.3 1.0 1 0 0 1 1 1 1 ATP11 protein SLT_L PF14718.6 CBY12572.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.1 3 0 0 3 3 3 0 Soluble lytic murein transglycosylase L domain UCH PF00443.29 CBY12573.1 - 2.2e-52 178.1 3.3 2.8e-52 177.8 3.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY12573.1 - 3.4e-13 49.9 8.7 1.9e-12 47.4 8.7 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.22 CBY12574.1 - 2.2e-14 53.0 0.1 2.9e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIF5_SNase_1 PF18187.1 CBY12574.1 - 0.0099 15.6 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 TbRIF5 SNase domain 1 zf-RING_2 PF13639.6 CBY12575.1 - 1.1e-05 25.6 19.4 1.1e-05 25.6 19.4 2.6 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CBY12575.1 - 6.2e-05 22.9 20.4 6.2e-05 22.9 20.4 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY12575.1 - 0.0011 18.8 17.2 0.0011 18.8 17.2 3.0 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CBY12575.1 - 0.0079 15.6 6.7 0.0079 15.6 6.7 1.4 2 0 0 2 2 2 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 CBY12575.1 - 0.0099 15.7 17.0 0.0099 15.7 17.0 3.3 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBY12575.1 - 0.13 12.3 20.6 0.058 13.4 14.8 2.8 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY12575.1 - 3.5 7.5 28.3 0.12 12.2 18.8 3.1 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY12575.1 - 3.7 7.4 20.5 0.32 10.8 14.7 2.4 2 0 0 2 2 2 0 RING-like zinc finger Host_attach PF10116.9 CBY12576.1 - 0.042 14.4 2.1 0.049 14.2 0.2 1.9 2 0 0 2 2 2 0 Protein required for attachment to host cells Comm PF15957.5 CBY12577.1 - 0.093 13.1 0.2 0.22 11.9 0.0 1.6 2 0 0 2 2 2 0 Commissureless Mito_morph_reg PF14972.6 CBY12577.1 - 0.096 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator Fer4_5 PF12801.7 CBY12577.1 - 0.1 12.6 5.7 0.066 13.2 3.6 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain Baculo_11_kDa PF06143.11 CBY12577.1 - 0.4 10.3 2.3 0.4 10.3 1.0 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family CYYR1 PF10873.8 CBY12577.1 - 1.4 9.3 4.3 0.71 10.3 1.9 1.6 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 Host_attach PF10116.9 CBY12578.1 - 0.019 15.5 0.8 0.049 14.2 0.2 1.8 2 0 0 2 2 2 0 Protein required for attachment to host cells Kelch_6 PF13964.6 CBY12579.1 - 0.0012 19.1 0.5 0.69 10.3 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CBY12579.1 - 0.0013 18.7 0.7 2.1 8.5 0.1 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CBY12579.1 - 0.042 13.9 3.4 3.5 7.7 0.1 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain EGF_CA PF07645.15 CBY12580.1 - 1.2e-77 255.9 151.4 1.5e-10 41.1 9.0 10.2 10 0 0 10 10 10 10 Calcium-binding EGF domain cEGF PF12662.7 CBY12580.1 - 1.9e-43 146.0 61.8 1.3e-05 25.0 0.7 11.1 10 0 0 10 10 10 9 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY12580.1 - 3.4e-29 100.8 120.4 1.9e-08 34.3 5.8 10.6 9 3 2 11 11 11 9 EGF domain EGF PF00008.27 CBY12580.1 - 3.9e-23 81.4 85.6 3.2e-05 24.1 2.4 10.5 9 2 0 9 9 9 9 EGF-like domain EGF_MSP1_1 PF12946.7 CBY12580.1 - 4.7e-22 77.7 129.8 7.9e-06 25.8 5.4 10.6 10 1 0 10 10 10 7 MSP1 EGF domain 1 hEGF PF12661.7 CBY12580.1 - 4.4e-16 58.8 86.7 0.0012 19.4 1.9 11.6 11 0 0 11 11 11 9 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY12580.1 - 9.5e-15 54.6 98.8 0.045 14.0 1.7 9.7 7 2 2 9 9 9 9 Coagulation Factor Xa inhibitory site DUF123 PF01986.16 CBY12580.1 - 0.33 11.5 2.9 76 3.9 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF123 adh_short PF00106.25 CBY12583.1 - 4.5e-26 91.5 0.0 5.7e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY12583.1 - 4.8e-16 59.0 0.0 5.1e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY12583.1 - 2.4e-06 27.6 0.0 5.9e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 CBY12583.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Kelch_2 PF07646.15 CBY12584.1 - 8.1e-05 22.4 1.8 0.22 11.6 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Glyoxal_oxid_N PF07250.11 CBY12584.1 - 0.0099 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 CBY12584.1 - 0.012 15.9 0.7 0.41 11.0 0.3 2.8 2 0 0 2 2 2 0 Kelch motif FSA_C PF10479.9 CBY12585.1 - 8.5 4.4 14.0 12 3.9 14.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 CBY12585.1 - 8.7 6.3 41.0 9.4 6.2 39.9 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein GMC_oxred_C PF05199.13 CBY12586.1 - 6.9e-37 127.2 0.0 1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase RVT_1 PF00078.27 CBY12587.1 - 1.5e-31 109.7 0.0 4.7e-31 108.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CBY12587.1 - 0.056 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Kelch_2 PF07646.15 CBY12590.1 - 1.4e-06 28.0 4.8 0.21 11.6 0.1 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 CBY12590.1 - 1.5e-06 28.2 5.9 0.31 11.4 0.1 5.4 5 0 0 5 5 5 2 Kelch motif DUF4871 PF16167.5 CBY12590.1 - 0.018 15.0 1.5 0.26 11.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4871) PFU PF09070.11 CBY12590.1 - 0.082 13.2 2.0 11 6.4 0.2 2.4 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) Homez PF11569.8 CBY12591.1 - 0.0013 18.1 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeodomain PF00046.29 CBY12591.1 - 0.074 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Homeodomain Prot_ATP_OB_N PF17758.1 CBY12592.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Prot_ATP_ID_OB PF16450.5 CBY12592.1 - 0.043 13.8 0.2 0.084 12.8 0.2 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Kelch_6 PF13964.6 CBY12593.1 - 0.00019 21.6 0.2 0.45 10.9 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY12593.1 - 0.13 12.3 0.4 3 7.9 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Lectin_C PF00059.21 CBY12594.1 - 2.1e-13 50.9 4.1 1e-11 45.5 0.2 2.5 3 0 0 3 3 3 2 Lectin C-type domain RT_RNaseH PF17917.1 CBY12596.1 - 5.2e-30 103.8 0.2 1.1e-29 102.8 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY12596.1 - 2.6e-29 101.2 0.0 6.5e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY12596.1 - 7e-23 81.1 0.0 5.3e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY12596.1 - 1.6e-13 50.5 0.2 5e-13 48.9 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CBY12596.1 - 0.00016 21.3 0.0 0.00035 20.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CBY12596.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF4691 PF15762.5 CBY12598.1 - 0.0008 19.6 1.1 1.2 9.3 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4691) DBD_Tnp_Mut PF03108.15 CBY12598.1 - 0.56 10.2 5.6 12 6.0 0.6 2.7 2 0 0 2 2 2 0 MuDR family transposase Ogr_Delta PF04606.12 CBY12598.1 - 0.71 9.9 5.2 26 4.9 0.1 4.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger SET PF00856.28 CBY12599.1 - 3.2e-09 37.4 0.0 6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 SET domain RRM_1 PF00076.22 CBY12600.1 - 2.5e-09 36.8 0.1 3.6e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY12600.1 - 0.00017 21.6 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif adh_short PF00106.25 CBY12601.1 - 1.7e-25 89.7 0.3 1.8e-20 73.3 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY12601.1 - 2.2e-16 60.1 0.1 3.1e-13 49.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY12601.1 - 1.1e-07 32.0 0.7 4.1e-07 30.1 0.2 2.0 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 CBY12601.1 - 0.034 13.9 0.2 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PCNA_N PF00705.18 CBY12602.1 - 2.5e-11 43.4 0.1 3.9e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 CBY12602.1 - 1.1e-09 37.8 1.9 0.00031 19.9 0.1 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.15 CBY12602.1 - 6.3e-05 23.2 0.1 0.00043 20.4 0.0 2.3 1 1 1 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain DEAD PF00270.29 CBY12603.1 - 1.1e-14 54.6 0.0 2.2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY12603.1 - 4.1e-11 43.2 0.0 1.4e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY12603.1 - 5.3e-07 29.8 0.0 9.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 CBY12603.1 - 0.0017 17.3 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 RecQ_Zn_bind PF16124.5 CBY12603.1 - 0.0062 17.2 1.2 0.018 15.7 1.2 1.9 1 0 0 1 1 1 1 RecQ zinc-binding Pkinase PF00069.25 CBY12605.1 - 1.6e-14 53.9 0.0 1.9e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain CHGN PF05679.16 CBY12606.1 - 5.6e-136 454.4 0.0 6.9e-136 454.1 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Coprogen_oxidas PF01218.18 CBY12606.1 - 0.02 13.6 0.3 1.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Coproporphyrinogen III oxidase Pkinase PF00069.25 CBY12607.1 - 1.3e-10 41.1 0.1 1.3e-10 41.1 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12607.1 - 3.8e-09 36.2 0.0 9.1e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.6 CBY12607.1 - 0.23 11.6 7.0 6.5 7.0 0.0 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF3896) DUF1981 PF09324.10 CBY12608.1 - 0.065 13.1 0.3 0.32 10.9 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) RecO_N PF11967.8 CBY12608.1 - 0.083 12.9 0.0 25 4.9 0.0 2.7 2 0 0 2 2 2 0 Recombination protein O N terminal Tubulin PF00091.25 CBY12609.1 - 3.2e-69 233.1 0.0 5.3e-69 232.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY12609.1 - 1.6e-43 147.8 0.1 2.7e-43 147.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY12609.1 - 9.1e-06 26.0 0.0 2.5e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBY12609.1 - 0.007 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBY12609.1 - 0.015 14.5 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Prominin PF05478.11 CBY12610.1 - 3.2e-10 38.7 7.1 4.5e-10 38.2 7.1 1.1 1 0 0 1 1 1 1 Prominin DUF1642 PF07852.11 CBY12610.1 - 0.093 13.3 0.4 0.64 10.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1642) DM PF00751.18 CBY12612.1 - 3.8e-24 84.3 10.9 5.9e-24 83.7 10.9 1.3 1 0 0 1 1 1 1 DM DNA binding domain Peptidase_C93 PF06035.11 CBY12612.1 - 0.076 12.8 0.2 0.094 12.5 0.2 1.1 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP M20_dimer PF07687.14 CBY12613.1 - 1.2e-10 41.2 0.0 1.3e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase dimerisation domain CAP PF00188.26 CBY12614.1 - 2.2e-30 106.1 0.2 8.1e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family SOAR PF16533.5 CBY12614.1 - 0.096 12.7 1.7 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 STIM1 Orai1-activating region CT_A_B PF02626.15 CBY12614.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain A and B Phospholip_A2_1 PF00068.19 CBY12615.1 - 3.7e-12 46.7 14.6 3.7e-12 46.7 14.6 1.9 1 1 0 1 1 1 1 Phospholipase A2 TPR_7 PF13176.6 CBY12616.1 - 3.3e-06 26.7 0.1 0.61 10.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY12616.1 - 3.4e-06 26.7 1.2 0.0014 18.5 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY12616.1 - 9.8e-06 25.2 1.2 0.00073 19.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY12616.1 - 0.00057 20.5 0.8 0.27 12.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY12616.1 - 0.0063 16.8 0.6 2.3 8.6 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY12616.1 - 0.012 15.8 0.6 7 7.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY12616.1 - 0.098 13.3 1.9 6.6 7.5 0.1 2.8 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY12616.1 - 0.68 10.5 4.3 1.1e+02 3.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Phospholip_A2_1 PF00068.19 CBY12618.1 - 1.6e-15 57.5 7.6 1.6e-15 57.5 7.6 1.9 2 0 0 2 2 2 1 Phospholipase A2 ERp29_N PF07912.13 CBY12619.1 - 2.2e-35 121.5 0.3 4.1e-35 120.7 0.3 1.5 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.12 CBY12619.1 - 9.7e-22 77.7 8.2 2.7e-21 76.3 8.2 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain 7tm_1 PF00001.21 CBY12619.1 - 1.1e-10 41.3 5.4 1.1e-10 41.3 5.4 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 CBY12619.1 - 0.031 13.6 3.6 0.018 14.4 1.3 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF4781 PF16013.5 CBY12619.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) DUF4358 PF14270.6 CBY12619.1 - 0.66 10.3 5.3 13 6.1 2.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) FYVE_2 PF02318.16 CBY12620.1 - 0.023 14.9 2.1 0.031 14.5 2.1 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Pox_A_type_inc PF04508.12 CBY12620.1 - 0.13 12.2 6.2 2 8.4 0.1 3.2 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat zf-RING-like PF08746.11 CBY12621.1 - 0.39 11.1 10.2 0.48 10.8 4.0 2.5 2 0 0 2 2 2 0 RING-like domain PHD_2 PF13831.6 CBY12621.1 - 0.51 9.9 4.6 1.4 8.6 4.6 1.8 1 0 0 1 1 1 0 PHD-finger ERp29_N PF07912.13 CBY12622.1 - 3.2e-36 124.3 0.3 5.2e-36 123.6 0.3 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.12 CBY12622.1 - 2.4e-22 79.7 8.0 2.4e-22 79.7 8.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain DUF4358 PF14270.6 CBY12622.1 - 0.047 14.0 5.2 3.3 8.1 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) DUF4167 PF13763.6 CBY12622.1 - 0.063 13.4 1.0 0.66 10.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) FYVE_2 PF02318.16 CBY12623.1 - 0.036 14.3 3.0 0.05 13.8 3.0 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Pox_A_type_inc PF04508.12 CBY12623.1 - 0.13 12.2 6.2 2 8.4 0.1 3.2 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat zf-RING-like PF08746.11 CBY12624.1 - 0.39 11.1 10.2 0.48 10.8 4.0 2.5 2 0 0 2 2 2 0 RING-like domain PHD_2 PF13831.6 CBY12624.1 - 0.51 9.9 4.6 1.4 8.6 4.6 1.8 1 0 0 1 1 1 0 PHD-finger EF-hand_7 PF13499.6 CBY12625.1 - 1e-09 38.7 1.9 1e-09 38.7 1.9 3.7 3 2 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY12625.1 - 8.1e-08 31.3 5.2 0.0022 17.4 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY12625.1 - 9.5e-08 31.4 1.3 0.00072 19.3 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBY12625.1 - 4.3e-05 23.3 0.1 0.0002 21.2 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY12625.1 - 0.00061 19.2 0.0 0.0062 16.0 0.0 2.6 2 0 0 2 2 2 1 EF hand DUF883 PF05957.13 CBY12625.1 - 0.0032 18.0 8.9 0.0032 18.0 8.9 4.3 4 1 1 5 5 5 1 Bacterial protein of unknown function (DUF883) TPR_2 PF07719.17 CBY12626.1 - 6.3e-30 100.9 12.5 0.00049 20.0 0.1 9.2 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBY12626.1 - 7.3e-30 101.5 15.4 1.7e-05 24.5 0.0 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 CBY12626.1 - 2.5e-24 83.4 10.9 0.00015 21.7 0.1 8.2 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 CBY12626.1 - 7.8e-22 76.7 11.0 2.2e-06 27.3 1.0 6.8 3 3 3 6 6 6 4 TPR repeat TPR_16 PF13432.6 CBY12626.1 - 1.8e-18 66.9 1.0 2.7e-06 27.9 0.6 5.2 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBY12626.1 - 5.1e-18 64.1 3.3 0.005 17.1 0.2 6.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_9 PF13371.6 CBY12626.1 - 5e-17 61.8 0.7 0.00011 22.3 0.2 5.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY12626.1 - 1.4e-16 60.7 8.9 9.1e-06 26.1 0.4 6.3 4 3 3 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 CBY12626.1 - 3e-16 59.3 4.4 3e-16 59.3 4.4 3.1 1 1 1 2 2 2 1 DnaJ domain TPR_14 PF13428.6 CBY12626.1 - 2.1e-15 56.1 8.5 0.0099 16.6 0.1 8.9 5 3 5 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY12626.1 - 1.7e-13 50.6 9.4 0.0055 17.0 0.1 6.6 3 2 2 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY12626.1 - 2.2e-10 40.6 7.8 0.00024 21.3 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBY12626.1 - 8.2e-09 35.5 8.8 0.046 14.4 0.1 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY12626.1 - 4.1e-07 29.6 9.1 0.38 10.9 0.0 6.9 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 CBY12626.1 - 1.3e-06 28.6 16.4 0.0046 17.3 0.1 5.6 3 2 2 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBY12626.1 - 0.0037 17.1 9.8 12 6.0 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY12626.1 - 0.018 15.1 7.9 1.5 9.0 0.3 4.8 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 CBY12626.1 - 0.029 14.4 2.3 6.7 6.8 0.0 3.3 4 1 0 4 4 3 0 Anaphase-promoting complex subunit 5 DUF4919 PF16266.5 CBY12626.1 - 0.034 14.1 6.6 1.1 9.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) HrpB1_HrpK PF09613.10 CBY12626.1 - 0.082 12.6 0.7 1.6 8.4 0.0 3.3 2 2 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) SHNi-TPR PF10516.9 CBY12626.1 - 0.085 12.3 0.0 5.7 6.5 0.1 3.4 3 0 0 3 3 3 0 SHNi-TPR NARP1 PF12569.8 CBY12626.1 - 0.12 11.2 33.0 0.1 11.5 2.7 4.8 1 1 1 4 4 4 0 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 CBY12626.1 - 2.3 8.6 14.1 0.23 11.9 0.3 4.0 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation Pkinase PF00069.25 CBY12627.1 - 1.4e-72 244.3 0.0 2.1e-72 243.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12627.1 - 4.6e-40 137.5 0.0 7e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_8 PF11835.8 CBY12627.1 - 9.1e-11 41.8 0.0 2.4e-10 40.5 0.0 1.7 2 0 0 2 2 1 1 RRM-like domain Kinase-like PF14531.6 CBY12627.1 - 2e-06 27.4 0.0 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.22 CBY12627.1 - 2.9e-06 27.0 0.0 8.5e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY12627.1 - 4e-06 26.4 0.0 9.7e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Haspin_kinase PF12330.8 CBY12627.1 - 0.0011 18.0 1.7 0.003 16.6 1.7 1.5 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBY12627.1 - 0.0026 17.4 1.0 0.0039 16.8 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 CBY12627.1 - 0.03 13.7 0.2 0.057 12.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY12627.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sox17_18_mid PF12067.8 CBY12627.1 - 5.4 7.1 7.3 22 5.2 0.1 3.2 3 0 0 3 3 3 0 Sox 17/18 central domain Bax1-I PF01027.20 CBY12628.1 - 8.5e-10 38.8 13.1 1e-09 38.5 13.1 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.11 CBY12628.1 - 0.051 13.5 8.9 0.06 13.2 8.9 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling Vma12 PF11712.8 CBY12628.1 - 0.44 10.6 5.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Presenilin PF01080.17 CBY12628.1 - 1.4 7.6 11.1 2 7.1 11.1 1.3 1 0 0 1 1 1 0 Presenilin SLATT_5 PF18160.1 CBY12628.1 - 3.2 7.0 6.2 2.2 7.5 3.9 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4231 PF14015.6 CBY12628.1 - 3.8 8.0 9.0 2.2 8.8 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Bax1-I PF01027.20 CBY12629.1 - 5e-12 46.1 4.3 5.4e-12 46.0 4.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.32 CBY12630.1 - 3.3e-52 173.3 22.7 3.2e-08 34.1 0.0 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY12630.1 - 7.9e-19 67.8 0.9 0.00025 21.3 0.2 6.1 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CBY12630.1 - 4.6e-08 33.5 0.1 8.1e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 CBY12630.1 - 0.00016 21.1 0.0 2.6 7.3 0.0 3.6 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CBY12630.1 - 0.00017 20.6 0.0 0.81 8.6 0.0 3.6 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBY12630.1 - 0.00034 20.6 0.0 1.1 9.1 0.0 3.7 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CBY12630.1 - 0.0073 16.2 0.7 24 5.0 0.0 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat ASH PF15780.5 CBY12630.1 - 0.018 15.2 0.0 6.2 7.1 0.0 3.0 2 1 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin IKI3 PF04762.12 CBY12630.1 - 0.13 10.3 0.0 0.33 8.9 0.0 1.7 2 0 0 2 2 2 0 IKI3 family AAA PF00004.29 CBY12631.1 - 4.9e-60 201.7 0.1 5.8e-42 143.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY12631.1 - 4.4e-16 58.4 0.2 1.7e-08 34.2 0.1 2.4 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 CBY12631.1 - 3.1e-09 36.9 0.1 0.00046 20.2 0.1 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBY12631.1 - 3.7e-08 33.7 0.1 0.0013 19.1 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_16 PF13191.6 CBY12631.1 - 4.2e-08 33.7 0.2 0.054 13.9 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain DUF815 PF05673.13 CBY12631.1 - 1.8e-07 30.6 0.0 0.013 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBY12631.1 - 2.3e-07 30.7 0.0 0.00065 19.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBY12631.1 - 1.1e-06 29.0 2.2 0.84 9.9 0.0 5.0 2 2 3 5 5 5 1 AAA domain ABC_tran PF00005.27 CBY12631.1 - 5e-06 27.1 0.0 0.065 13.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_2 PF07724.14 CBY12631.1 - 1.3e-05 25.4 0.0 0.0032 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 CBY12631.1 - 5.4e-05 23.2 0.9 0.04 13.8 0.0 3.5 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CBY12631.1 - 0.00012 22.1 0.0 0.04 14.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CBY12631.1 - 0.00016 21.7 0.0 0.038 13.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Bac_DnaA PF00308.18 CBY12631.1 - 0.0002 21.2 0.3 0.11 12.3 0.6 3.2 2 1 0 2 2 2 1 Bacterial dnaA protein NACHT PF05729.12 CBY12631.1 - 0.00027 20.9 0.0 7.7 6.4 0.0 4.2 2 2 2 4 4 4 0 NACHT domain AAA_7 PF12775.7 CBY12631.1 - 0.00052 19.6 0.0 0.96 8.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 CBY12631.1 - 0.00092 19.2 0.0 0.75 9.8 0.0 3.2 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CBY12631.1 - 0.0013 18.0 0.0 0.011 15.0 0.1 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_3 PF07726.11 CBY12631.1 - 0.003 17.4 0.0 0.81 9.6 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBY12631.1 - 0.0042 17.6 0.0 4.6 7.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBY12631.1 - 0.0052 16.5 0.0 0.91 9.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBY12631.1 - 0.0056 16.1 0.0 0.05 13.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CBY12631.1 - 0.0064 15.8 0.0 0.49 9.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 CBY12631.1 - 0.0083 15.8 0.1 11 5.7 0.0 3.7 3 2 1 4 4 4 0 Sigma-54 interaction domain NB-ARC PF00931.22 CBY12631.1 - 0.0083 15.3 0.0 1.5 7.9 0.0 3.1 2 1 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.6 CBY12631.1 - 0.009 16.4 0.2 3.5 8.0 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 CBY12631.1 - 0.01 16.0 0.0 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain OSCP PF00213.18 CBY12631.1 - 0.015 15.4 0.0 0.077 13.1 0.0 2.1 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit AAA_24 PF13479.6 CBY12631.1 - 0.019 14.7 0.3 5.4 6.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CBY12631.1 - 0.024 14.2 0.9 3.8 7.1 0.1 3.3 2 2 1 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 CBY12631.1 - 0.04 14.0 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 CBY12631.1 - 0.041 13.1 0.0 0.1 11.8 0.0 1.7 1 0 0 1 1 1 0 KAP family P-loop domain RsgA_GTPase PF03193.16 CBY12631.1 - 0.065 13.1 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase ATP-synt_ab PF00006.25 CBY12631.1 - 0.092 12.4 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 CBY12631.1 - 0.13 12.5 0.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 CBY12632.1 - 1.3e-11 44.6 11.8 2.3e-11 43.8 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY12632.1 - 4.4e-07 29.6 11.9 7.9e-07 28.8 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY12632.1 - 6.3e-06 26.4 11.8 1.8e-05 24.9 11.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBY12632.1 - 4.2e-05 23.2 6.2 4.2e-05 23.2 6.2 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 CBY12632.1 - 0.00011 22.0 12.3 0.0002 21.1 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY12632.1 - 0.00013 21.8 11.1 0.00022 21.1 11.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY12632.1 - 0.00072 19.5 7.2 0.0016 18.4 7.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY12632.1 - 0.0061 16.4 8.3 0.011 15.6 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY12632.1 - 0.01 15.9 6.7 0.035 14.1 6.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBY12632.1 - 0.09 12.6 8.3 0.17 11.8 8.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 CBY12632.1 - 1.5 9.0 10.7 1.9 8.7 9.7 1.7 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 CBY12632.1 - 2.7 7.7 9.4 1.7 8.3 7.1 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CBY12632.1 - 5.3 7.3 9.4 15 5.9 9.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_5 PF17121.5 CBY12632.1 - 5.8 6.9 8.1 16 5.5 8.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SPRR2 PF14820.6 CBY12633.1 - 0.069 13.2 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Small proline-rich 2 Kri1 PF05178.12 CBY12633.1 - 0.082 13.5 2.4 1.4 9.5 1.5 2.7 2 1 1 3 3 3 0 KRI1-like family Arm PF00514.23 CBY12634.1 - 1.1e-17 63.4 7.7 1.4e-06 28.1 0.1 6.5 6 1 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CBY12634.1 - 0.00057 20.3 0.4 0.71 10.4 0.0 3.5 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 CBY12634.1 - 0.0016 18.8 1.1 0.3 11.5 0.1 2.8 3 0 0 3 3 3 2 HEAT repeats DUF4298 PF14131.6 CBY12634.1 - 0.15 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) PLAC8 PF04749.17 CBY12635.1 - 1.8e-12 48.1 7.3 2.5e-12 47.7 7.3 1.2 1 0 0 1 1 1 1 PLAC8 family Zip PF02535.22 CBY12637.1 - 1.6e-37 129.5 14.7 1.9e-29 103.0 7.7 3.1 1 1 2 3 3 3 2 ZIP Zinc transporter CENP-B_dimeris PF09026.10 CBY12637.1 - 0.012 16.0 12.9 0.33 11.4 12.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.12 CBY12637.1 - 0.044 12.0 2.0 0.065 11.4 2.0 1.2 1 0 0 1 1 1 0 Nop14-like family SirB PF04247.12 CBY12637.1 - 0.4 10.8 3.2 0.27 11.3 0.6 2.0 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF2457 PF10446.9 CBY12637.1 - 0.55 9.3 17.2 0.47 9.5 15.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 CBY12637.1 - 1.3 7.5 3.0 1.8 7.0 3.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CBY12637.1 - 1.9 6.5 12.9 3.4 5.7 12.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 CBY12637.1 - 4.8 6.8 6.6 2.3 7.9 3.5 2.0 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 CBY12637.1 - 7.2 4.8 7.7 11 4.1 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2796 PF10986.8 CBY12637.1 - 8.4 6.3 19.4 25 4.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Myosin_head PF00063.21 CBY12638.1 - 2.1e-200 667.4 7.8 2.5e-200 667.2 7.8 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CBY12638.1 - 0.0032 17.9 0.0 0.0082 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY12638.1 - 0.025 14.9 0.0 0.081 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CBY12638.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PRK PF00485.18 CBY12638.1 - 0.093 12.5 0.1 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Kringle PF00051.18 CBY12639.1 - 3.8e-12 46.3 5.8 7.8e-12 45.4 5.8 1.6 1 1 0 1 1 1 1 Kringle domain Kringle PF00051.18 CBY12640.1 - 1.9e-18 66.6 9.2 4.6e-18 65.3 6.5 2.1 2 0 0 2 2 2 1 Kringle domain Phage-MuB_C PF09077.11 CBY12640.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Mu B transposition protein, C terminal TFIIA PF03153.13 CBY12641.1 - 3.1 7.7 10.1 4.8 7.1 10.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Carb_anhydrase PF00194.21 CBY12642.1 - 3.5e-40 138.2 3.6 4.8e-40 137.7 3.6 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Claudin_2 PF13903.6 CBY12643.1 - 7.2e-05 22.6 0.1 0.0024 17.6 0.3 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction EF-hand_7 PF13499.6 CBY12644.1 - 7.1e-07 29.6 0.1 0.037 14.5 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY12644.1 - 3.8e-06 26.4 2.7 0.32 11.0 0.0 4.7 4 1 1 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 CBY12644.1 - 0.00012 21.8 0.1 0.041 13.7 0.1 3.6 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY12644.1 - 0.0011 18.3 4.4 0.27 10.9 0.0 5.0 5 0 0 5 5 5 1 EF hand YIEGIA PF14045.6 CBY12645.1 - 0.024 13.5 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 YIEGIA protein Kelch_6 PF13964.6 CBY12646.1 - 6.5e-05 23.1 0.1 0.007 16.6 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 CBY12646.1 - 0.016 15.2 2.2 0.48 10.5 0.2 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 CBY12646.1 - 0.34 11.3 3.3 4.1 7.8 0.2 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain ABC_tran PF00005.27 CBY12648.1 - 1.1e-18 68.1 0.0 8.6e-16 58.7 0.0 2.2 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CBY12648.1 - 2.4e-05 24.3 0.0 6.9e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 CBY12648.1 - 0.00012 22.0 0.3 0.46 10.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY12648.1 - 0.00013 21.5 0.1 0.21 11.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 CBY12648.1 - 0.00032 20.7 0.0 0.0027 17.7 0.0 2.0 1 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CBY12648.1 - 0.0066 17.0 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBY12648.1 - 0.008 16.3 0.2 0.014 15.4 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY12648.1 - 0.016 15.5 0.1 0.024 14.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY12648.1 - 0.017 14.8 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CBY12648.1 - 0.026 14.9 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CBY12648.1 - 0.029 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 CBY12648.1 - 0.034 13.9 0.0 1.3 8.7 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain DnaB_C PF03796.15 CBY12648.1 - 0.036 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NB-ARC PF00931.22 CBY12648.1 - 0.039 13.1 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 CBY12648.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain ATPase PF06745.13 CBY12648.1 - 0.066 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 CBY12648.1 - 0.089 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBY12648.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.18 CBY12648.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Rad17 PF03215.15 CBY12648.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 CBY12648.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 CBY12648.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CBY12648.1 - 0.21 11.8 0.1 0.36 11.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY12648.1 - 0.23 11.2 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Glyco_hydro_35 PF01301.19 CBY12650.1 - 7.9e-101 337.8 0.0 1.2e-100 337.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY12650.1 - 7.4e-11 42.0 0.1 2.2e-09 37.2 0.0 2.4 2 1 0 2 2 2 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 CBY12650.1 - 0.11 13.1 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain ABC_tran PF00005.27 CBY12651.1 - 1.3e-22 80.7 0.0 1.8e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY12651.1 - 6.6e-06 26.1 0.2 0.053 13.3 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY12651.1 - 0.00057 19.4 0.4 0.012 15.0 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY12651.1 - 0.00069 19.6 0.2 0.0042 17.0 0.0 2.2 3 0 0 3 3 3 1 RsgA GTPase ATPase_2 PF01637.18 CBY12651.1 - 0.0024 17.8 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 CBY12651.1 - 0.0056 16.7 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBY12651.1 - 0.019 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CBY12651.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CBY12651.1 - 0.051 13.3 0.0 1.9 8.1 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 CBY12651.1 - 0.057 13.9 0.3 0.057 13.9 0.3 2.0 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 CBY12651.1 - 0.062 13.7 0.1 0.082 13.3 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 CBY12651.1 - 0.066 13.3 0.3 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 CBY12651.1 - 0.094 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CBY12651.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 CBY12651.1 - 0.11 12.7 0.1 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBY12651.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 CBY12651.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 CBY12651.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 CBY12651.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 CBY12651.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_35 PF01301.19 CBY12653.1 - 5.5e-121 404.0 0.1 1.1e-88 297.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY12653.1 - 2.8e-09 36.8 0.0 9.2e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase FBA PF04300.13 CBY12653.1 - 0.0001 22.1 0.2 0.22 11.2 0.0 2.7 2 0 0 2 2 2 2 F-box associated region BetaGal_dom4_5 PF13364.6 CBY12653.1 - 0.017 15.7 0.1 0.48 11.0 0.0 2.6 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain XisH PF08814.10 CBY12653.1 - 0.11 12.6 0.4 6.4 6.9 0.1 2.4 2 0 0 2 2 2 0 XisH protein FemAB_like PF04339.12 CBY12654.1 - 0.091 11.9 0.7 0.084 12.0 0.7 1.1 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition Ammonium_transp PF00909.21 CBY12655.1 - 1.3e-87 294.1 13.1 2.5e-87 293.2 13.1 1.4 1 1 0 1 1 1 1 Ammonium Transporter Family ThrE PF06738.12 CBY12655.1 - 8.2 5.7 8.5 0.8 9.0 0.6 2.6 2 1 0 2 2 2 0 Putative threonine/serine exporter Glyco_transf_7N PF13733.6 CBY12656.1 - 2.9e-36 124.1 0.6 4.6e-36 123.4 0.6 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY12656.1 - 9.5e-26 89.3 1.7 1.6e-25 88.5 0.9 1.7 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase MFS_2 PF13347.6 CBY12657.1 - 7.6e-29 100.5 16.1 9.3e-20 70.6 2.9 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 CBY12657.1 - 3.3e-11 42.7 29.4 1.8e-08 33.7 5.8 3.2 3 1 1 4 4 4 3 Major Facilitator Superfamily LacY_symp PF01306.19 CBY12657.1 - 0.00034 19.5 0.9 0.00034 19.5 0.9 2.6 2 0 0 2 2 2 1 LacY proton/sugar symporter PGG PF13962.6 CBY12657.1 - 0.2 11.5 3.2 0.17 11.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function Dimer_Tnp_hAT PF05699.14 CBY12658.1 - 7.2e-08 32.1 0.1 1.1e-07 31.5 0.1 1.3 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Glyco_hydro_79n PF03662.14 CBY12659.1 - 7.3e-23 81.0 0.3 1.1e-22 80.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_79n PF03662.14 CBY12660.1 - 4.7e-28 98.0 0.6 5.8e-18 64.9 0.3 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain DUF1080 PF06439.11 CBY12661.1 - 0.00073 19.7 1.2 13 5.9 0.0 3.7 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1080) PHD PF00628.29 CBY12661.1 - 0.0085 16.0 1.8 0.024 14.5 1.8 1.7 1 0 0 1 1 1 1 PHD-finger Aegerolysin PF06355.13 CBY12661.1 - 0.015 15.4 1.8 2.6 8.2 0.0 3.5 4 0 0 4 4 4 0 Aegerolysin WRC PF08879.10 CBY12661.1 - 0.12 12.0 0.2 0.43 10.3 0.2 1.9 1 0 0 1 1 1 0 WRC Pkinase PF00069.25 CBY12663.1 - 4.7e-71 239.2 0.3 2.2e-70 237.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12663.1 - 7.5e-40 136.8 0.1 4.3e-39 134.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY12663.1 - 1.4e-09 37.7 0.0 2.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY12663.1 - 7.4e-05 22.8 0.5 0.00017 21.6 0.6 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY12663.1 - 0.00014 20.9 0.2 0.00014 20.9 0.2 2.4 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CBY12663.1 - 0.00041 19.8 0.3 0.00074 18.9 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CBY12663.1 - 0.0037 16.4 0.0 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Ribosomal_L21p PF00829.21 CBY12663.1 - 0.21 11.9 1.4 0.28 11.5 0.2 1.8 2 0 0 2 2 2 0 Ribosomal prokaryotic L21 protein Pkinase_fungal PF17667.1 CBY12663.1 - 0.24 10.1 6.2 0.28 9.9 0.0 2.5 3 0 0 3 3 3 0 Fungal protein kinase CDI PF02234.19 CBY12664.1 - 2.7e-14 53.1 1.6 3.3e-14 52.8 0.3 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor PHC2_SAM_assoc PF16616.5 CBY12664.1 - 0.14 13.0 7.1 0.23 12.3 7.0 1.5 1 1 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Cytochrom_C PF00034.21 CBY12664.1 - 0.29 12.3 1.7 0.53 11.5 1.6 1.4 1 1 0 1 1 1 0 Cytochrome c Kelch_1 PF01344.25 CBY12665.1 - 0.031 13.9 5.9 0.032 13.8 2.5 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 CBY12665.1 - 0.067 13.5 0.1 0.24 11.8 0.1 2.0 1 0 0 1 1 1 0 Galactose oxidase, central domain PhoLip_ATPase_C PF16212.5 CBY12666.1 - 2.9e-42 145.2 7.7 2.9e-42 145.2 7.7 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBY12666.1 - 5.1e-21 74.1 3.0 5.1e-21 74.1 3.0 2.1 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CBY12666.1 - 1e-10 41.5 0.1 1.3e-09 38.0 0.0 2.6 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY12666.1 - 1.9e-10 41.4 0.6 0.00015 22.1 0.1 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CBY12666.1 - 2.7e-07 30.3 0.0 6.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBY12666.1 - 0.016 15.0 0.0 0.016 15.0 0.0 2.3 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase BON PF04972.17 CBY12666.1 - 0.066 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 BON domain ZapB PF06005.12 CBY12666.1 - 0.13 12.8 0.2 0.42 11.1 0.2 1.9 1 0 0 1 1 1 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 CBY12666.1 - 0.23 11.7 2.6 0.74 10.1 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Phospholip_A2_1 PF00068.19 CBY12667.1 - 2.2e-14 53.9 5.8 2.2e-14 53.9 5.8 2.3 3 0 0 3 3 3 1 Phospholipase A2 Dimer_Tnp_hAT PF05699.14 CBY12668.1 - 2.1e-07 30.6 0.6 2.8e-07 30.2 0.6 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Phospholip_A2_1 PF00068.19 CBY12670.1 - 4.2e-14 53.0 3.8 4.2e-14 53.0 3.8 2.4 3 0 0 3 3 3 1 Phospholipase A2 TMEM171 PF15471.6 CBY12671.1 - 0.092 11.7 0.3 0.15 11.0 0.3 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Cyt-b5 PF00173.28 CBY12673.1 - 1.6e-11 44.2 0.1 3.2e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 CBY12673.1 - 7.1e-10 39.1 11.8 2.3e-09 37.5 11.8 1.9 1 1 0 1 1 1 1 Fatty acid desaturase DDDD PF10161.9 CBY12673.1 - 0.1 12.3 0.5 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Putative mitochondrial precursor protein 2TM PF13239.6 CBY12673.1 - 0.98 9.8 4.4 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 2TM domain C2-set_2 PF08205.12 CBY12674.1 - 0.023 14.8 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 CBY12674.1 - 0.12 13.0 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain ADAM_CR_2 PF17771.1 CBY12675.1 - 1.7e-11 44.4 7.8 1.7e-11 44.4 7.8 5.4 4 2 1 5 5 5 2 ADAM cysteine-rich domain TSP_1 PF00090.19 CBY12675.1 - 2.2e-09 37.4 9.8 2.2e-09 37.4 9.8 6.9 8 0 0 8 8 8 2 Thrombospondin type 1 domain Reprolysin PF01421.19 CBY12675.1 - 6.4e-08 32.7 0.0 6.4e-08 32.7 0.0 2.0 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 CBY12675.1 - 0.0058 16.8 0.1 0.015 15.5 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 CBY12675.1 - 0.055 13.1 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 CBY12675.1 - 0.059 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Glyco_hydro_20 PF00728.22 CBY12676.1 - 1.6e-76 258.0 5.0 2.4e-76 257.4 5.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CBY12676.1 - 5.7e-08 33.5 0.1 1.6e-07 32.1 0.1 1.8 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CBY12676.1 - 7.6e-05 23.5 0.0 0.00016 22.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ets PF00178.22 CBY12677.1 - 2.3e-33 114.5 0.2 3.7e-33 113.8 0.2 1.3 1 0 0 1 1 1 1 Ets-domain Kelch_1 PF01344.25 CBY12678.1 - 2.5e-49 164.6 10.5 1.5e-11 43.7 0.1 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBY12678.1 - 2.7e-30 103.6 1.9 6e-06 26.4 0.0 6.8 4 2 2 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CBY12678.1 - 2.5e-26 91.4 3.4 1.2e-06 28.6 0.0 6.5 6 0 0 6 6 6 3 Galactose oxidase, central domain BTB PF00651.31 CBY12678.1 - 3.2e-25 88.5 1.2 7.7e-24 84.1 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 CBY12678.1 - 2.6e-21 75.6 0.4 6.8e-21 74.3 0.4 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CBY12678.1 - 5.7e-19 67.9 3.1 0.00059 19.8 0.0 5.7 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY12678.1 - 1.4e-16 59.7 3.6 0.0023 17.9 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 CBY12678.1 - 5e-14 51.9 1.7 0.15 12.1 0.1 6.5 6 0 0 6 6 6 5 Kelch motif EABR PF12180.8 CBY12678.1 - 0.02 14.5 0.2 0.04 13.5 0.2 1.4 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 BTG PF07742.12 CBY12679.1 - 2e-36 124.3 0.0 4.2e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 BTG family zf-C4 PF00105.18 CBY12680.1 - 7.6e-27 93.6 13.0 1.1e-26 93.1 13.0 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 CBY12680.1 - 4.1 7.8 12.1 0.27 11.6 2.6 2.5 2 1 0 2 2 2 0 C1 domain LRR_6 PF13516.6 CBY12681.1 - 0.00015 21.5 0.9 1 9.6 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 CBY12681.1 - 0.0011 18.7 3.8 0.79 9.5 0.6 3.5 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBY12681.1 - 0.065 13.7 5.7 0.17 12.3 1.4 3.1 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY12681.1 - 1.4 9.7 10.3 2.1 9.2 0.1 4.5 3 3 0 3 3 3 0 Leucine Rich Repeat DUF745 PF05335.13 CBY12682.1 - 0.0052 16.5 6.3 0.0052 16.5 6.3 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF745) ADIP PF11559.8 CBY12682.1 - 0.014 15.5 5.3 0.014 15.5 5.3 3.6 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding Noelin-1 PF12308.8 CBY12682.1 - 0.069 13.1 1.7 0.34 10.9 1.7 2.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein CALCOCO1 PF07888.11 CBY12682.1 - 0.14 11.0 25.5 0.2 10.5 25.5 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Holin_BhlA PF10960.8 CBY12682.1 - 0.87 9.6 6.2 0.38 10.8 2.1 2.5 2 0 0 2 2 2 0 BhlA holin family GCR1_C PF12550.8 CBY12682.1 - 0.87 9.9 6.2 0.25 11.7 1.7 2.3 2 1 0 2 2 2 0 Transcriptional activator of glycolytic enzymes OmpH PF03938.14 CBY12682.1 - 2.2 8.6 20.9 5.7 7.3 8.0 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ABC_tran_CTD PF16326.5 CBY12682.1 - 4.1 7.7 15.0 0.79 10.0 5.1 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF641 PF04859.12 CBY12682.1 - 6.7 7.1 17.7 7.6 6.9 2.8 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CorA PF01544.18 CBY12682.1 - 7.3 5.8 14.9 69 2.6 14.8 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1041 PF06292.17 CBY12683.1 - 3.8e-17 62.6 0.8 3.8e-17 62.6 0.8 1.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) PH PF00169.29 CBY12683.1 - 3.8e-08 33.8 0.1 7.9e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 PH domain C2 PF00168.30 CBY12683.1 - 0.001 19.3 0.1 0.0027 17.9 0.1 1.8 1 0 0 1 1 1 1 C2 domain TMPIT PF07851.13 CBY12684.1 - 0.011 15.0 6.4 0.013 14.8 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF641 PF04859.12 CBY12684.1 - 0.035 14.4 13.3 0.047 14.0 1.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CC2-LZ PF16516.5 CBY12684.1 - 0.068 13.5 1.5 0.068 13.5 1.5 3.3 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator KxDL PF10241.9 CBY12684.1 - 0.076 13.3 14.3 2.8 8.3 0.2 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 CBY12684.1 - 0.094 12.8 10.6 1.4 9.0 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 CBY12684.1 - 0.15 12.7 13.0 0.16 12.6 1.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Bacillus_HBL PF05791.11 CBY12684.1 - 0.21 11.4 0.2 0.21 11.4 0.2 2.3 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMF_TATA_bd PF12325.8 CBY12684.1 - 0.25 11.6 14.6 0.17 12.1 12.0 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Snapin_Pallidin PF14712.6 CBY12684.1 - 0.29 11.6 9.8 0.4 11.1 7.7 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Tropomyosin_1 PF12718.7 CBY12684.1 - 0.41 10.8 19.7 0.32 11.1 8.9 2.2 1 1 1 2 2 2 0 Tropomyosin like Herpes_UL25 PF01499.16 CBY12684.1 - 0.53 8.7 5.9 0.67 8.4 5.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Atg14 PF10186.9 CBY12684.1 - 0.56 9.2 16.0 0.43 9.6 13.6 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2968 PF11180.8 CBY12684.1 - 1.3 8.7 14.8 1.6 8.3 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) BLOC1_2 PF10046.9 CBY12684.1 - 1.7 9.0 11.5 0.99 9.8 7.8 2.1 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.6 CBY12684.1 - 1.8 8.6 12.1 4.4 7.4 11.3 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 UPF0242 PF06785.11 CBY12684.1 - 2.2 8.4 17.2 2.6 8.1 15.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 CBY12684.1 - 3.9 5.3 7.6 4.3 5.1 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GP20 PF06810.11 CBY12684.1 - 6.4 6.6 18.9 16 5.2 18.4 2.1 1 1 0 1 1 1 0 Phage minor structural protein GP20 Rx_N PF18052.1 CBY12684.1 - 10 6.5 12.5 1.7 8.9 0.2 2.9 1 1 2 3 3 3 0 Rx N-terminal domain Sulfotransfer_1 PF00685.27 CBY12686.1 - 2.4e-05 24.0 0.0 2.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.14 CBY12686.1 - 0.0015 18.5 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 CBY12686.1 - 0.054 13.9 0.0 9.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase family Mucin PF01456.17 CBY12686.1 - 0.24 11.4 0.0 0.35 10.8 0.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Sulfotransfer_1 PF00685.27 CBY12687.1 - 0.027 14.0 0.1 0.03 13.8 0.1 1.0 1 0 0 1 1 1 0 Sulfotransferase domain CRAL_TRIO PF00650.20 CBY12688.1 - 8.9e-26 90.5 0.0 1.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CBY12688.1 - 2.8e-06 27.4 0.3 1.2e-05 25.4 0.2 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CHASE2 PF05226.11 CBY12688.1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain Nmad5 PF18757.1 CBY12688.1 - 0.4 10.9 0.1 0.4 10.9 0.1 1.7 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 Aa_trans PF01490.18 CBY12689.1 - 1.2e-61 208.6 34.0 9.9e-37 126.6 12.8 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein WD40 PF00400.32 CBY12690.1 - 6.2e-36 121.8 4.6 1.2e-09 38.7 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY12690.1 - 1.2e-10 41.5 0.0 9.9e-05 22.6 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY12690.1 - 6.1e-07 28.5 1.1 0.0081 14.9 0.0 4.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 HPS3_N PF14761.6 CBY12690.1 - 0.0024 17.5 0.0 0.4 10.2 0.0 3.3 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 Cytochrom_D1 PF02239.16 CBY12690.1 - 0.13 10.7 0.0 0.95 7.9 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Dor1 PF04124.12 CBY12691.1 - 2.1e-104 348.8 5.0 9.4e-104 346.7 4.5 1.9 2 0 0 2 2 2 1 Dor1-like family Vps51 PF08700.11 CBY12691.1 - 6.3e-06 26.2 0.0 3.2e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Vps54_N PF10475.9 CBY12691.1 - 0.00031 20.1 1.5 0.00031 20.1 1.5 1.6 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Cdc6_C PF09079.11 CBY12691.1 - 0.1 12.6 0.0 0.5 10.4 0.1 2.1 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain PhoU PF01895.19 CBY12691.1 - 0.31 11.5 4.1 1.6 9.3 0.2 3.2 3 0 0 3 3 3 0 PhoU domain CPSase_L_D2 PF02786.17 CBY12692.1 - 6e-81 271.0 0.0 9.8e-81 270.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBY12692.1 - 4.7e-45 152.6 0.1 1.9e-44 150.7 0.1 2.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBY12692.1 - 9.7e-36 122.2 0.0 2.9e-35 120.6 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBY12692.1 - 1.4e-16 60.1 6.2 1.4e-16 60.1 2.6 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBY12692.1 - 1.2e-08 34.7 0.4 0.0011 18.7 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like PCC_BT PF18140.1 CBY12692.1 - 1.6e-08 34.9 0.0 4.2e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 CBY12692.1 - 1.9e-08 34.1 0.3 4.1e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBY12692.1 - 1.9e-07 30.8 0.1 7.2e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CBY12692.1 - 0.00077 19.5 0.1 0.0018 18.4 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CBY12692.1 - 0.0018 17.9 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain RnfC_N PF13375.6 CBY12692.1 - 0.0077 16.2 1.1 0.96 9.4 0.1 3.2 4 0 0 4 4 4 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 CBY12692.1 - 0.056 12.7 0.3 1 8.6 0.1 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 CBY12692.1 - 0.063 12.5 0.0 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_5 PF13549.6 CBY12692.1 - 0.091 12.2 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain HlyD_3 PF13437.6 CBY12692.1 - 0.1 13.3 1.1 4.3 8.1 0.2 2.9 2 1 1 3 3 2 0 HlyD family secretion protein Aminotran_5 PF00266.19 CBY12693.1 - 1.4e-60 205.3 0.0 1.8e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CBY12693.1 - 3.1e-06 26.6 0.0 2.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DIL PF01843.19 CBY12694.1 - 2e-31 108.3 1.3 2e-31 108.3 1.3 2.3 2 0 0 2 2 2 1 DIL domain RA PF00788.23 CBY12694.1 - 1.5e-21 76.8 0.0 9.8e-12 45.4 0.0 3.3 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 CBY12694.1 - 8.1e-16 58.2 0.0 2e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY12694.1 - 6.3e-06 25.9 0.1 2e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CBY12694.1 - 0.00016 21.9 0.0 0.0005 20.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain DZF PF07528.14 CBY12695.1 - 8.1e-26 91.1 0.0 4.4e-22 78.9 0.0 2.7 1 1 1 2 2 2 2 DZF domain dsrm PF00035.26 CBY12695.1 - 1.5e-19 70.4 19.2 5.1e-09 36.7 0.7 4.1 4 0 0 4 4 4 3 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CBY12695.1 - 1.1e-11 44.8 3.4 0.005 17.0 0.2 4.3 4 0 0 4 4 4 3 Dicer dimerisation domain CH_2 PF06294.11 CBY12696.1 - 1e-26 92.9 0.1 2.8e-26 91.5 0.1 1.8 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBY12696.1 - 2.5e-08 33.6 0.0 7.2e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 CAMSAP CH domain CH PF00307.31 CBY12696.1 - 0.017 15.3 0.1 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Calponin homology (CH) domain Methyltransf_16 PF10294.9 CBY12697.1 - 3.2e-22 79.1 0.0 4.1e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CBY12697.1 - 6.3e-05 22.5 0.0 7.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CBY12697.1 - 0.0028 18.3 0.0 0.0038 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY12697.1 - 0.0062 16.4 0.0 0.0083 16.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CBY12697.1 - 0.019 14.1 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CBY12697.1 - 0.065 14.0 0.0 0.1 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CBY12697.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Sof1 PF04158.14 CBY12698.1 - 1.6e-28 98.8 6.7 3.5e-28 97.7 6.7 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CBY12698.1 - 7.6e-19 67.7 13.3 0.00035 21.3 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY12698.1 - 1.7e-06 28.2 0.2 0.01 16.1 0.0 4.4 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CBY12698.1 - 0.00014 20.4 0.0 0.011 14.1 0.0 2.6 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 CBY12698.1 - 0.00083 19.3 0.0 0.0088 15.9 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBY12698.1 - 0.016 14.2 0.2 0.12 11.4 0.2 2.2 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SdiA-regulated PF06977.11 CBY12698.1 - 0.039 13.2 0.0 0.095 11.9 0.0 1.6 1 0 0 1 1 1 0 SdiA-regulated SGL PF08450.12 CBY12698.1 - 0.063 12.8 0.7 0.3 10.6 0.7 2.2 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region S-AdoMet_synt_N PF00438.20 CBY12700.1 - 7e-06 26.6 0.1 7.2e-06 26.6 0.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_C PF02773.16 CBY12701.1 - 1.8e-65 219.1 0.2 3.3e-65 218.2 0.0 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CBY12701.1 - 1.9e-44 150.7 0.2 3.3e-44 150.0 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CBY12701.1 - 3.6e-11 43.6 0.2 1.5e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain SelP_N PF04592.14 CBY12702.1 - 0.013 14.9 9.7 0.022 14.2 9.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ABC2_membrane_3 PF12698.7 CBY12702.1 - 0.51 9.4 9.1 0.79 8.8 6.6 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Phospholip_A2_1 PF00068.19 CBY12704.1 - 4.3e-10 40.1 0.5 4.3e-10 40.1 0.5 1.5 2 0 0 2 2 2 1 Phospholipase A2 Tryp_inh PF17983.1 CBY12704.1 - 0.046 13.8 6.1 1.5 8.9 0.0 3.3 3 0 0 3 3 3 0 Trypsin inhibitors 1,2 and 3 Tryp_inh PF17983.1 CBY12706.1 - 0.076 13.1 6.8 1.5 9.0 0.0 3.2 3 0 0 3 3 3 0 Trypsin inhibitors 1,2 and 3 DUF4600 PF15372.6 CBY12707.1 - 1.2e-37 129.2 21.5 2.2e-37 128.4 10.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4600) Spc7 PF08317.11 CBY12707.1 - 0.11 11.4 23.6 0.088 11.7 22.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Prominin PF05478.11 CBY12707.1 - 0.13 10.2 9.8 0.16 9.9 9.8 1.2 1 0 0 1 1 1 0 Prominin YscO-like PF16789.5 CBY12707.1 - 0.19 11.7 18.9 1.2 9.1 9.7 2.3 2 0 0 2 2 2 0 YscO-like protein PI_PP_I PF18363.1 CBY12707.1 - 1.4 9.1 6.7 0.59 10.3 2.9 2.1 1 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF3450 PF11932.8 CBY12707.1 - 2.4 7.4 20.0 0.11 11.8 13.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sec20 PF03908.13 CBY12707.1 - 2.7 8.0 6.5 2.1 8.3 4.2 2.0 1 1 0 2 2 2 0 Sec20 BRE1 PF08647.11 CBY12707.1 - 3.8 7.7 28.9 0.47 10.6 15.9 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase RyR PF02026.16 CBY12707.1 - 3.9 7.7 9.0 0.41 10.9 1.2 2.3 2 0 0 2 2 2 0 RyR domain THOC7 PF05615.13 CBY12707.1 - 5.4 7.3 23.4 0.14 12.4 14.8 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4407 PF14362.6 CBY12707.1 - 6.4 6.0 20.9 14 5.0 20.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2748 PF10871.8 CBY12707.1 - 7.5 5.1 10.9 0.86 8.2 4.7 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2748) APC_N_CC PF16689.5 CBY12707.1 - 8.2 6.6 14.8 1.9 8.6 0.5 2.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Band_7 PF01145.25 CBY12709.1 - 7.1e-33 114.1 0.3 8.8e-33 113.8 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY12709.1 - 0.006 16.3 0.1 0.0087 15.8 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family adh_short PF00106.25 CBY12710.1 - 4.1e-49 166.7 1.2 5.5e-49 166.3 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY12710.1 - 1.4e-47 162.2 0.4 1.8e-47 161.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY12710.1 - 6.6e-13 49.0 0.4 9.7e-13 48.4 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CBY12710.1 - 0.056 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF218 PF02698.17 CBY12710.1 - 0.16 12.0 0.1 0.64 10.0 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain DUF1011 PF06237.12 CBY12711.1 - 2.9e-28 98.1 9.0 2.9e-28 98.1 9.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1011) Phospholip_A2_1 PF00068.19 CBY12712.1 - 5.7e-15 55.8 6.0 5.7e-15 55.8 6.0 2.2 2 1 0 2 2 2 1 Phospholipase A2 PI3K_rbd PF00794.18 CBY12712.1 - 0.15 12.2 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain LLC1 PF14945.6 CBY12713.1 - 4.5e-32 111.1 2.5 6e-32 110.7 2.5 1.2 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Glyco_hydro_1 PF00232.18 CBY12714.1 - 1.4e-140 468.7 12.5 1.6e-140 468.5 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Ldh_1_N PF00056.23 CBY12715.1 - 0.0028 17.7 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain SLATT_fungal PF18142.1 CBY12715.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Nucleos_tra2_C PF07662.13 CBY12716.1 - 3.3e-69 232.9 5.6 3.3e-69 232.9 5.6 2.2 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CBY12716.1 - 2.9e-19 69.4 2.5 2.9e-19 69.4 2.5 3.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CBY12716.1 - 3.4e-05 24.1 9.4 3.4e-05 24.1 9.4 4.3 5 0 0 5 5 5 1 Nucleoside recognition UPF0227 PF05728.12 CBY12716.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) bMG1 PF17970.1 CBY12718.1 - 0.037 14.1 0.1 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG1 domain ArAE_2_N PF10337.9 CBY12718.1 - 0.099 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal E1-E2_ATPase PF00122.20 CBY12719.1 - 3.1e-29 101.8 5.1 3.8e-27 95.0 2.5 2.2 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 CBY12719.1 - 1.5e-17 63.1 2.0 4e-17 61.7 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.9 CBY12719.1 - 0.054 13.3 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Amidase_6 PF12671.7 CBY12719.1 - 0.13 12.4 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative amidase domain AbrB PF05145.12 CBY12719.1 - 0.14 11.1 0.2 0.21 10.5 0.2 1.2 1 0 0 1 1 1 0 Transition state regulatory protein AbrB Kelch_6 PF13964.6 CBY12720.1 - 0.0079 16.5 3.2 7.2 7.1 0.1 3.5 2 1 1 3 3 3 2 Kelch motif YL1_C PF08265.11 CBY12721.1 - 0.17 11.7 0.4 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain RT_RNaseH_2 PF17919.1 CBY12722.1 - 2.8e-22 78.6 0.0 8.7e-22 77.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY12722.1 - 2.4e-13 50.3 0.0 5.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY12722.1 - 3.9e-13 49.4 0.0 7.1e-12 45.3 0.0 2.3 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 CBY12722.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Lactamase_B_6 PF16661.5 CBY12722.1 - 0.071 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain RT_RNaseH PF17917.1 CBY12724.1 - 7.4e-29 100.1 0.2 1.3e-27 96.1 0.1 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY12724.1 - 1.2e-25 89.4 0.0 1.5e-24 85.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 CBY12724.1 - 0.12 12.2 0.1 1.2 9.0 0.1 2.3 1 1 0 1 1 1 0 Reverse transcriptase thumb domain UPF0016 PF01169.19 CBY12725.1 - 6.1e-37 125.8 21.7 5.3e-21 74.7 9.9 2.4 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 GRP PF07172.11 CBY12725.1 - 1.5 9.6 3.9 0.44 11.3 0.4 1.9 2 0 0 2 2 2 0 Glycine rich protein family ThiF PF00899.21 CBY12726.1 - 1.2e-20 74.0 0.0 3.1e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 CBY12726.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CBY12726.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 5_nucleotid PF05761.14 CBY12727.1 - 3.9e-31 108.4 3.7 5.7e-31 107.9 3.7 1.0 1 0 0 1 1 1 1 5' nucleotidase family DUF4477 PF14780.6 CBY12727.1 - 0.15 11.7 0.2 0.27 10.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Ribosomal_L21e PF01157.18 CBY12728.1 - 8.4e-45 150.8 6.1 8.4e-45 150.8 6.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e Noc2 PF03715.13 CBY12729.1 - 2.7e-30 105.6 1.3 2.7e-30 105.6 1.3 1.8 2 0 0 2 2 2 1 Noc2p family Pinin_SDK_memA PF04696.13 CBY12729.1 - 0.5 10.4 0.1 0.5 10.4 0.1 3.2 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Nop14 PF04147.12 CBY12729.1 - 4.9 5.2 25.0 6.6 4.8 25.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF423 PF04241.15 CBY12730.1 - 1.7e-13 50.6 3.4 2.7e-13 49.9 2.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF423) DUF4386 PF14329.6 CBY12730.1 - 0.18 11.7 1.6 0.29 11.0 1.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4386) Noc2 PF03715.13 CBY12731.1 - 4e-25 88.7 0.0 6.1e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Noc2p family V_ATPase_I PF01496.19 CBY12731.1 - 4 5.2 10.7 5.3 4.8 10.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SPG4 PF17325.2 CBY12731.1 - 4.1 8.5 11.5 0.4 11.8 5.0 2.1 2 0 0 2 2 2 0 Stationary phase protein 4 BTB PF00651.31 CBY12732.1 - 2.1e-24 85.9 0.1 3.6e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain HMG_box PF00505.19 CBY12732.1 - 8.6e-08 32.5 0.1 2.1e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY12732.1 - 0.00064 20.3 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain HD-ZIP_N PF04618.12 CBY12732.1 - 0.077 13.5 0.5 0.077 13.5 0.5 2.2 2 1 1 3 3 3 0 HD-ZIP protein N terminus Trypsin PF00089.26 CBY12733.1 - 1.5e-38 132.8 0.2 5.5e-38 131.0 0.2 1.9 1 1 0 1 1 1 1 Trypsin Kringle PF00051.18 CBY12733.1 - 3.8e-22 78.4 22.4 1.3e-13 51.1 3.3 3.6 4 0 0 4 4 4 2 Kringle domain Trypsin_2 PF13365.6 CBY12733.1 - 0.027 15.3 0.0 0.063 14.2 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain LOH1CR12 PF10158.9 CBY12734.1 - 0.0025 17.8 2.6 0.0025 17.8 2.6 7.3 2 2 4 7 7 7 1 Tumour suppressor protein TMF_TATA_bd PF12325.8 CBY12734.1 - 0.011 15.9 14.0 0.011 15.9 14.0 9.3 2 2 8 10 10 10 0 TATA element modulatory factor 1 TATA binding NCD1 PF04904.13 CBY12734.1 - 0.092 12.8 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) S_2TMBeta PF18153.1 CBY12734.1 - 0.099 12.4 0.4 0.31 10.8 0.4 1.8 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain HSBP1 PF06825.12 CBY12734.1 - 0.54 10.2 11.3 3.5 7.6 0.1 5.8 6 0 0 6 6 6 0 Heat shock factor binding protein 1 CRAL_TRIO PF00650.20 CBY12735.1 - 4.1e-21 75.3 0.1 9.5e-21 74.2 0.1 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CBY12735.1 - 2.4e-05 24.4 0.0 6.6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PRANC PF09372.10 CBY12735.1 - 0.039 14.3 1.2 0.89 9.9 0.2 2.4 2 0 0 2 2 2 0 PRANC domain Glyco_transf_7N PF13733.6 CBY12736.1 - 3.1e-38 130.4 0.1 5.9e-38 129.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY12736.1 - 1.1e-27 95.5 1.2 1.9e-27 94.7 1.2 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Rad60-SLD PF11976.8 CBY12736.1 - 0.063 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RRM_1 PF00076.22 CBY12737.1 - 1.7e-09 37.4 0.2 0.00021 21.0 0.1 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY12737.1 - 0.013 15.7 0.0 2.1 8.5 0.0 2.6 1 1 1 2 2 2 0 RNA recognition motif DUF1947 PF09183.10 CBY12738.1 - 0.035 14.4 0.8 0.06 13.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) PAC1 PF16094.5 CBY12739.1 - 0.36 9.9 1.5 0.53 9.4 1.5 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 RecG_N PF17190.4 CBY12739.1 - 3.2 8.6 11.7 0.15 12.8 4.7 2.2 2 0 0 2 2 2 0 RecG N-terminal helical domain zf-UBR PF02207.20 CBY12740.1 - 1.6e-09 37.8 9.5 2.9e-09 37.0 9.5 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DAGK_cat PF00781.24 CBY12741.1 - 3.1e-24 85.0 0.2 5e-24 84.3 0.2 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Stathmin PF00836.19 CBY12742.1 - 3.8e-10 39.8 4.1 4.1e-10 39.7 4.1 1.0 1 0 0 1 1 1 1 Stathmin family Sulfotransfer_4 PF17784.1 CBY12743.1 - 1.7e-40 139.2 0.0 2.4e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Snapin_Pallidin PF14712.6 CBY12744.1 - 5.3e-07 30.0 24.0 0.00016 22.0 0.7 7.6 4 3 2 7 7 7 1 Snapin/Pallidin Spc7 PF08317.11 CBY12744.1 - 1e-06 27.9 49.0 0.0032 16.4 6.7 5.9 2 2 5 7 7 7 5 Spc7 kinetochore protein DUF1664 PF07889.12 CBY12744.1 - 3.4e-05 23.9 44.4 0.59 10.2 0.8 8.2 1 1 6 8 8 8 3 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CBY12744.1 - 4.9e-05 23.4 39.8 0.14 12.2 3.9 7.4 3 3 3 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus C1q PF00386.21 CBY12744.1 - 9.5e-05 22.6 0.1 0.00029 21.0 0.1 1.9 1 0 0 1 1 1 1 C1q domain DUF4407 PF14362.6 CBY12744.1 - 0.0011 18.4 33.8 0.088 12.1 2.4 4.4 2 1 2 4 4 4 3 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 CBY12744.1 - 0.0017 18.4 9.6 0.0017 18.4 9.6 7.4 2 2 6 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 CBY12744.1 - 0.0024 18.1 35.0 1.6 9.0 0.3 8.5 4 4 4 8 8 8 2 Bacterial protein of unknown function (DUF948) CAP_N PF01213.19 CBY12744.1 - 0.0038 16.7 5.0 0.0038 16.7 5.0 3.7 4 0 0 4 4 4 1 Adenylate cyclase associated (CAP) N terminal DUF5082 PF16888.5 CBY12744.1 - 0.0064 16.8 3.6 0.0064 16.8 3.6 7.4 2 2 4 7 7 6 1 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 CBY12744.1 - 0.0065 16.9 41.7 0.0068 16.9 1.5 8.6 5 3 3 8 8 8 2 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 CBY12744.1 - 0.0081 16.4 9.8 0.0081 16.4 9.8 5.4 2 2 2 4 4 4 2 Autophagy protein 16 (ATG16) FliJ PF02050.16 CBY12744.1 - 0.011 15.9 0.1 0.011 15.9 0.1 5.6 4 3 1 5 5 5 0 Flagellar FliJ protein FlaC_arch PF05377.11 CBY12744.1 - 0.011 16.1 44.2 2 8.9 0.2 10.9 10 0 0 10 10 10 0 Flagella accessory protein C (FlaC) BclA_C PF18573.1 CBY12744.1 - 0.016 15.1 0.5 0.043 13.7 0.5 1.7 1 0 0 1 1 1 0 BclA C-terminal domain Tropomyosin_1 PF12718.7 CBY12744.1 - 0.026 14.7 49.0 0.049 13.8 1.9 7.3 2 2 4 6 6 6 0 Tropomyosin like Prominin PF05478.11 CBY12744.1 - 0.065 11.2 40.2 0.11 10.4 2.8 4.5 2 1 3 5 5 5 0 Prominin Filament PF00038.21 CBY12744.1 - 0.19 11.3 48.2 2.5 7.6 1.1 6.4 2 2 2 4 4 4 0 Intermediate filament protein bZIP_1 PF00170.21 CBY12744.1 - 0.37 10.9 16.5 1.2 9.3 0.2 6.2 7 1 0 7 7 7 0 bZIP transcription factor Laminin_II PF06009.12 CBY12744.1 - 0.44 10.6 45.0 2.5 8.1 4.6 7.6 4 3 5 9 9 9 0 Laminin Domain II eIF-5a PF01287.20 CBY12744.1 - 0.62 10.2 6.3 0.81 9.8 0.0 3.7 5 0 0 5 5 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold WD40_alt PF14077.6 CBY12744.1 - 1 9.3 3.7 37 4.3 0.1 4.0 4 0 0 4 4 3 0 Alternative WD40 repeat motif Exonuc_VII_L PF02601.15 CBY12744.1 - 1.5 8.3 34.4 34 3.9 3.1 4.3 1 1 2 3 3 3 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 CBY12744.1 - 1.8 8.8 42.0 1.2 9.3 0.7 7.0 3 3 2 7 7 7 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 CBY12744.1 - 2.4 8.1 30.0 2.8 7.9 0.3 7.6 7 1 0 8 8 8 0 Prefoldin subunit DUF2536 PF10750.9 CBY12744.1 - 2.7 8.0 5.4 0.71 9.8 0.3 2.8 3 0 0 3 3 1 0 Protein of unknown function (DUF2536) DUF4472 PF14739.6 CBY12744.1 - 4 8.2 32.9 1.3 9.8 2.4 6.6 5 2 1 6 6 6 0 Domain of unknown function (DUF4472) TPR_MLP1_2 PF07926.12 CBY12744.1 - 6.8 6.8 50.2 1.4 9.0 1.2 6.8 4 3 3 7 7 7 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 CBY12744.1 - 8 6.5 43.5 2.7 8.0 8.5 5.5 3 3 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF2514 PF10721.9 CBY12744.1 - 9.8 6.2 8.1 17 5.4 0.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2514) Spectrin PF00435.21 CBY12744.1 - 9.9 6.7 32.8 0.66 10.5 0.7 7.4 4 3 2 7 7 7 0 Spectrin repeat LRR_8 PF13855.6 CBY12745.1 - 3.2e-32 110.1 20.7 2e-10 40.3 0.2 4.8 1 1 4 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 CBY12745.1 - 2.5e-14 53.3 0.1 1.6e-08 34.6 0.1 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY12745.1 - 1.9e-13 50.3 16.9 0.00087 19.6 1.0 6.4 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY12745.1 - 0.0062 16.9 13.0 42 5.3 0.3 7.6 8 2 0 8 8 8 0 Leucine Rich Repeat LRR_9 PF14580.6 CBY12745.1 - 0.011 15.2 4.8 0.18 11.3 0.7 2.5 1 1 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 CBY12745.1 - 0.21 11.8 13.6 30 5.0 0.0 6.8 8 0 0 8 8 8 0 Leucine Rich repeat Sushi PF00084.20 CBY12746.1 - 0.0051 17.4 17.5 0.035 14.7 2.6 3.5 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) Asn_synthase PF00733.21 CBY12747.1 - 1.1e-22 81.2 0.0 1.4e-19 71.0 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CBY12747.1 - 2.1e-13 50.2 0.0 5.4e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CBY12747.1 - 8.1e-09 35.8 0.0 5.6e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain CBM_X2 PF03442.14 CBY12747.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 GTP_EFTU PF00009.27 CBY12748.1 - 3.8e-50 170.1 0.1 6.5e-50 169.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBY12748.1 - 1e-15 57.6 0.0 2.4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CBY12748.1 - 0.00028 20.8 0.0 0.00063 19.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 CBY12748.1 - 0.00031 20.6 0.1 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CBY12748.1 - 0.0007 19.7 0.2 0.002 18.2 0.2 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AFP_2 PF18815.1 CBY12748.1 - 0.49 10.7 2.8 18 5.7 0.1 3.3 3 0 0 3 3 3 0 Bacterial antifreeze protein repeat YfcL PF08891.11 CBY12749.1 - 0.098 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 YfcL protein Sulfatase PF00884.23 CBY12752.1 - 1.4e-11 44.4 0.1 2.2e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Vps54_N PF10475.9 CBY12752.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Phospholip_A2_1 PF00068.19 CBY12753.1 - 1.5e-08 35.1 1.2 1.5e-08 35.1 1.2 1.5 2 0 0 2 2 2 1 Phospholipase A2 Sulfatase PF00884.23 CBY12754.1 - 2.7e-32 112.4 0.0 3.1e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase BAAT_C PF08840.11 CBY12755.1 - 9.8e-05 22.4 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 CBY12755.1 - 0.013 15.0 0.2 0.35 10.4 0.2 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_M19 PF01244.21 CBY12756.1 - 3.3e-79 266.3 0.0 2e-78 263.8 0.0 2.3 2 1 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) DUF883 PF05957.13 CBY12758.1 - 0.06 13.9 0.6 0.11 13.1 0.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YabA PF06156.13 CBY12758.1 - 0.43 11.2 6.6 0.15 12.7 2.6 2.0 1 1 0 2 2 2 0 Initiation control protein YabA DHR10 PF18595.1 CBY12758.1 - 1.4 9.0 9.4 14 5.7 9.4 2.1 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain UPF0449 PF15136.6 CBY12758.1 - 1.6 9.3 7.8 9.8 6.7 5.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 tRNA-synt_1c PF00749.21 CBY12760.1 - 2.6e-106 355.1 0.0 6.4e-106 353.8 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain WHEP-TRS PF00458.20 CBY12760.1 - 2.8e-97 318.8 74.2 1.8e-17 63.2 6.1 7.4 7 0 0 7 7 7 6 WHEP-TRS domain tRNA-synt_1c_C PF03950.18 CBY12760.1 - 1.5e-34 119.4 0.1 3.1e-34 118.4 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain ProRS-C_1 PF09180.11 CBY12760.1 - 4.8e-18 65.1 1.0 1.6e-17 63.5 1.0 2.0 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CBY12760.1 - 1.3e-16 60.6 0.0 1.5e-15 57.1 0.0 2.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBY12760.1 - 7.4e-16 58.6 0.0 1.5e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) GST_C PF00043.25 CBY12760.1 - 1.1e-05 25.5 0.1 0.00018 21.6 0.1 2.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY12760.1 - 0.00052 20.2 0.0 0.0049 17.0 0.0 2.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY12760.1 - 0.021 14.8 0.3 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RuvC PF02075.17 CBY12760.1 - 0.55 10.1 6.4 42 4.0 0.1 4.4 4 0 0 4 4 4 0 Crossover junction endodeoxyribonuclease RuvC WIYLD PF10440.9 CBY12760.1 - 0.74 9.7 5.2 62 3.5 0.0 4.3 4 0 0 4 4 4 0 Ubiquitin-binding WIYLD domain ApbA_C PF08546.11 CBY12760.1 - 2.5 8.3 4.9 1.1e+02 3.0 0.1 4.2 5 0 0 5 5 5 0 Ketopantoate reductase PanE/ApbA C terminal Ribosomal_L1 PF00687.21 CBY12761.1 - 1.1e-44 152.6 8.4 1.3e-44 152.4 8.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L22e PF01776.17 CBY12762.1 - 4e-39 133.4 6.6 4.5e-39 133.2 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Erf4 PF10256.9 CBY12763.1 - 0.033 14.3 0.5 0.076 13.1 0.2 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family TFIIB PF00382.19 CBY12764.1 - 2e-26 91.8 0.0 2.8e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CBY12764.1 - 4.8e-22 78.2 5.5 4.8e-22 78.2 5.5 3.1 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CBY12764.1 - 1.3e-10 40.6 2.4 1.3e-10 40.6 2.4 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 CBY12764.1 - 0.027 14.4 1.1 0.065 13.2 1.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RB_B PF01857.20 CBY12764.1 - 0.087 12.9 0.2 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Golgin_A5 PF09787.9 CBY12767.1 - 0.0011 18.5 12.6 0.0011 18.5 12.6 2.4 1 1 1 2 2 2 2 Golgin subfamily A member 5 Cep57_CLD PF14073.6 CBY12767.1 - 0.019 15.0 8.7 0.019 15.0 8.7 3.3 1 1 2 3 3 3 0 Centrosome localisation domain of Cep57 HPIP PF15226.6 CBY12767.1 - 0.14 12.5 0.2 0.4 11.1 0.2 1.8 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family IFT57 PF10498.9 CBY12767.1 - 3.2 6.6 34.2 0.76 8.7 23.5 2.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF2452 PF10504.9 CBY12768.1 - 8.5e-08 31.8 0.1 9.9e-08 31.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) fn3 PF00041.21 CBY12769.1 - 6.8e-36 122.5 21.5 1.4e-12 47.8 0.2 7.0 8 0 0 8 8 7 4 Fibronectin type III domain Ig_3 PF13927.6 CBY12769.1 - 4.7e-28 97.6 7.1 3.3e-09 37.2 0.1 5.6 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 CBY12769.1 - 4.7e-26 90.7 0.8 2.6e-07 30.6 0.0 5.5 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY12769.1 - 7.4e-26 90.3 6.3 4.4e-10 39.8 0.1 5.2 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.25 CBY12769.1 - 3.2e-16 59.3 10.5 7.7e-07 29.2 0.0 5.5 5 2 0 5 5 4 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY12769.1 - 5.7e-10 39.6 14.7 0.052 14.1 0.0 6.8 7 2 0 7 7 6 4 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 CBY12769.1 - 5.8e-10 39.3 14.7 0.071 13.3 0.1 7.9 5 3 3 8 8 8 4 Immunoglobulin V-set domain Ig_4 PF16680.5 CBY12769.1 - 9.1e-10 38.7 2.0 0.02 15.2 0.0 4.5 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Interfer-bind PF09294.10 CBY12769.1 - 5.4e-07 29.9 4.2 4 7.8 0.0 4.6 3 1 1 4 4 4 3 Interferon-alpha/beta receptor, fibronectin type III Izumo-Ig PF16706.5 CBY12769.1 - 2e-06 27.7 0.0 0.73 9.9 0.0 4.4 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Tissue_fac PF01108.17 CBY12769.1 - 0.00048 19.9 6.0 0.0012 18.6 0.1 3.6 4 0 0 4 4 4 1 Tissue factor Ig_6 PF18452.1 CBY12769.1 - 0.0056 16.2 0.0 4.1 7.0 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain FlgD_ig PF13860.6 CBY12769.1 - 0.093 12.6 0.0 0.46 10.4 0.0 2.3 1 0 0 1 1 1 0 FlgD Ig-like domain V-set_CD47 PF08204.11 CBY12769.1 - 0.16 12.0 0.2 3.8 7.5 0.0 3.3 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain DUF2452 PF10504.9 CBY12770.1 - 2.6e-24 85.5 1.4 2.9e-24 85.3 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) CBF_beta PF02312.17 CBY12770.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit Gemini_V2 PF01524.17 CBY12771.1 - 0.075 13.2 0.1 1.4 9.2 0.0 2.5 3 0 0 3 3 3 0 Geminivirus V2 protein SapA PF02199.15 CBY12772.1 - 3.6e-12 46.3 4.1 7.9e-12 45.3 2.3 2.2 2 0 0 2 2 2 1 Saposin A-type domain SapB_2 PF03489.17 CBY12772.1 - 1e-09 38.3 1.7 1e-09 38.3 1.7 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 2 Alpha-L-AF_C PF06964.12 CBY12773.1 - 0.06 13.5 0.1 0.069 13.3 0.1 1.1 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminal domain TM_helix PF05552.12 CBY12773.1 - 0.15 12.1 0.3 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 Conserved TM helix PPR_long PF17177.4 CBY12774.1 - 0.003 16.9 0.1 0.004 16.5 0.1 1.1 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP HSP20 PF00011.21 CBY12775.1 - 4.3e-11 42.9 0.5 6.2e-11 42.3 0.5 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family tRNA_lig_kinase PF08303.11 CBY12775.1 - 0.062 13.4 0.1 0.082 13.0 0.1 1.1 1 0 0 1 1 1 0 tRNA ligase kinase domain HSP20 PF00011.21 CBY12776.1 - 3e-10 40.2 0.4 3.7e-10 39.8 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family UNC-93 PF05978.16 CBY12777.1 - 2e-09 37.4 11.4 2e-09 37.4 11.4 3.8 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CBY12777.1 - 1.1e-06 27.8 12.5 1.1e-06 27.8 12.5 3.0 2 2 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CBY12777.1 - 0.0013 17.2 0.9 0.0021 16.5 0.9 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector YtpI PF14007.6 CBY12777.1 - 1.8 8.7 13.3 0.33 11.1 0.2 4.3 4 0 0 4 4 4 0 YtpI-like protein DUF1158 PF06643.11 CBY12777.1 - 2.5 8.7 8.8 2.9 8.5 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1158) Nudix_hydro PF18290.1 CBY12778.1 - 9.9e-23 79.9 0.1 1.6e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 CBY12778.1 - 9.1e-17 61.3 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ig_3 PF13927.6 CBY12779.1 - 5.2e-25 87.8 8.6 4.9e-09 36.7 0.5 6.9 4 2 2 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 CBY12779.1 - 4.6e-21 74.9 9.7 4.1e-09 36.7 0.3 6.2 3 2 2 5 5 5 5 Immunoglobulin domain I-set PF07679.16 CBY12779.1 - 2.7e-17 62.6 2.2 3.6e-08 33.4 0.3 5.6 5 1 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.25 CBY12779.1 - 2e-12 47.1 5.1 0.00058 20.0 0.3 6.4 5 3 1 6 6 6 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY12779.1 - 5.5e-12 45.6 3.4 0.0013 18.8 0.0 4.7 4 2 0 4 4 4 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 CBY12779.1 - 2.5e-07 31.0 0.6 0.00016 22.0 0.0 4.2 5 0 0 5 5 5 1 Immunoglobulin C1-set domain V-set PF07686.17 CBY12779.1 - 9.5e-05 22.5 6.6 0.42 10.8 0.3 4.7 5 2 1 6 6 5 2 Immunoglobulin V-set domain DUF4690 PF15756.5 CBY12779.1 - 0.0055 17.3 0.0 0.03 14.9 0.0 2.3 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Ig_C17orf99 PF17736.1 CBY12779.1 - 0.016 15.2 0.4 8.1 6.6 0.0 3.9 3 1 1 4 4 4 0 C17orf99 Ig domain TMEM154 PF15102.6 CBY12779.1 - 0.068 13.1 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family DUF4982 PF16355.5 CBY12779.1 - 0.12 12.3 0.4 30 4.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4982) Phage_sheath_1N PF17481.2 CBY12779.1 - 0.41 11.2 3.3 39 4.8 0.0 3.0 2 0 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain DUF11 PF01345.18 CBY12779.1 - 3.2 8.1 9.1 5 7.5 0.1 4.1 5 0 0 5 5 5 0 Domain of unknown function DUF11 P5CR_dimer PF14748.6 CBY12780.1 - 6.5e-36 122.7 2.6 1.1e-35 122.0 2.6 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CBY12780.1 - 2e-07 31.5 0.0 5.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Regulator_TrmB PF11495.8 CBY12780.1 - 0.001 18.3 0.1 0.0015 17.7 0.1 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB UPRTase PF14681.6 CBY12780.1 - 0.13 11.7 0.2 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase SIP1 PF04938.12 CBY12781.1 - 9.1e-11 41.9 0.6 1e-10 41.7 0.6 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) SIP1 PF04938.12 CBY12782.1 - 4e-05 23.4 0.1 4.6e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Dus PF01207.17 CBY12783.1 - 1.6e-68 231.1 0.0 2.8e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 CBY12783.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 CBY12783.1 - 0.041 13.7 0.1 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 SOR/SNZ family G3P_antiterm PF04309.12 CBY12783.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator dsDNA_bind PF01984.20 CBY12784.1 - 2e-28 98.9 16.0 2.4e-28 98.6 16.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain ribosomal_L24 PF17136.4 CBY12784.1 - 0.0033 17.8 0.3 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 FeoC PF09012.10 CBY12784.1 - 0.01 15.9 1.1 0.015 15.3 0.3 1.7 1 1 1 2 2 2 0 FeoC like transcriptional regulator DUF4808 PF16066.5 CBY12784.1 - 0.042 14.4 1.7 0.05 14.2 1.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4808) ATP12 PF07542.11 CBY12785.1 - 8.5e-27 93.8 0.2 1.4e-26 93.1 0.2 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Pribosyltran_N PF13793.6 CBY12786.1 - 3.2e-46 156.0 0.4 2.3e-45 153.2 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBY12786.1 - 6.3e-38 130.6 2.4 1.3e-31 110.0 1.6 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBY12786.1 - 1.5e-11 44.0 0.4 3.4e-11 42.9 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBY12786.1 - 0.0013 18.3 0.1 0.0023 17.4 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_tran_WecB PF03808.13 CBY12786.1 - 0.16 11.9 0.1 1.6 8.6 0.0 2.5 2 1 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family DNA_pol_phi PF04931.13 CBY12787.1 - 6.5e-73 246.1 18.5 6.5e-73 246.1 18.5 2.1 2 0 0 2 2 2 1 DNA polymerase phi ubiquitin PF00240.23 CBY12788.1 - 5.3e-30 103.0 0.3 6.4e-30 102.7 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY12788.1 - 1.9e-12 46.9 0.4 2.5e-12 46.4 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBY12788.1 - 1.4e-05 25.4 0.1 6.4e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CBY12788.1 - 0.0049 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBY12788.1 - 0.0054 16.6 0.0 0.0056 16.6 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBY12788.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBY12788.1 - 0.047 14.2 0.1 0.054 14.1 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 CBY12789.1 - 2.3e-07 30.5 0.0 2.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY12789.1 - 0.018 14.8 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3333 PF11812.8 CBY12789.1 - 0.035 14.3 0.0 0.039 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) ubiquitin PF00240.23 CBY12790.1 - 3.4e-07 29.9 0.1 3.8e-07 29.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY12790.1 - 0.016 15.1 0.1 0.017 15.0 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY12791.1 - 2.2e-45 152.3 5.5 1.8e-34 117.3 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CBY12791.1 - 4e-20 71.4 5.0 1.8e-16 59.7 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBY12791.1 - 4.5e-07 30.2 1.2 4.1e-05 23.9 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin-like domain Big_7 PF17957.1 CBY12791.1 - 0.00012 22.7 0.3 0.5 11.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial Ig domain Ubiquitin_4 PF18036.1 CBY12791.1 - 0.00048 20.1 6.4 3.3 7.8 0.2 3.0 3 0 0 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBY12791.1 - 0.0013 18.9 0.5 0.014 15.5 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CBY12791.1 - 0.0022 18.3 0.6 0.0032 17.8 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBY12791.1 - 0.0028 17.6 0.0 0.0049 16.8 0.0 1.5 1 1 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CBY12791.1 - 0.01 16.4 0.1 0.017 15.7 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CBY12791.1 - 0.013 15.4 0.1 0.18 11.7 0.0 2.0 1 1 1 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Big_3_3 PF13750.6 CBY12791.1 - 0.023 14.4 0.0 5.8 6.5 0.0 2.2 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) PurS PF02700.14 CBY12791.1 - 0.037 14.2 0.6 6.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase ACT_5 PF13710.6 CBY12791.1 - 0.04 13.8 0.3 10 6.1 0.0 2.3 2 0 0 2 2 2 0 ACT domain UDP-g_GGTase PF06427.11 CBY12791.1 - 0.044 13.9 0.4 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase PDGLE PF13190.6 CBY12791.1 - 0.056 13.4 1.2 2.5 8.0 0.1 2.4 1 1 1 2 2 2 0 PDGLE domain HATPase_c PF02518.26 CBY12791.1 - 0.094 13.2 0.4 0.17 12.4 0.4 1.5 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TmoB PF06234.12 CBY12791.1 - 0.26 11.4 1.4 15 5.7 0.1 2.5 2 1 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) AAA_25 PF13481.6 CBY12792.1 - 0.025 14.1 0.0 0.32 10.6 0.0 2.4 2 1 1 3 3 3 0 AAA domain PolyA_pol_RNAbd PF12627.7 CBY12792.1 - 0.038 13.7 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Phage_TAC_12 PF12363.8 CBY12792.1 - 0.12 12.8 0.0 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC zf-UBR PF02207.20 CBY12793.1 - 2.4e-17 62.8 13.3 3.5e-17 62.3 13.3 1.2 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) JUPITER PF17054.5 CBY12794.1 - 2.5e-05 23.9 0.8 0.00023 20.8 0.1 1.9 2 0 0 2 2 2 1 Microtubule-Associated protein Jupiter DUF4057 PF13266.6 CBY12794.1 - 0.0082 15.9 1.6 0.018 14.7 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF4057) Yip1 PF04893.17 CBY12797.1 - 0.0097 15.6 7.2 0.018 14.7 7.2 1.5 1 1 0 1 1 1 1 Yip1 domain TRAP_beta PF05753.14 CBY12797.1 - 0.11 11.9 0.5 13 5.1 0.1 2.3 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) DUF1240 PF06836.12 CBY12797.1 - 0.12 12.9 0.1 0.12 12.9 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) DUF4231 PF14015.6 CBY12797.1 - 0.44 11.0 3.5 5.3 7.6 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) 7tm_1 PF00001.21 CBY12798.1 - 2e-06 27.3 2.0 3.2e-06 26.7 2.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frag1 PF10277.9 CBY12798.1 - 0.0096 15.5 2.1 0.012 15.1 2.1 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2070 PF09843.9 CBY12798.1 - 0.013 13.8 0.6 0.013 13.9 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1361 PF07099.11 CBY12798.1 - 0.02 14.9 0.7 0.028 14.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) Phage_holin_1 PF04531.13 CBY12798.1 - 0.16 12.5 0.3 4.1 8.0 0.0 2.3 2 1 1 3 3 3 0 Bacteriophage holin Wzy_C_2 PF11846.8 CBY12798.1 - 0.19 11.7 0.6 0.31 10.9 0.6 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DZR PF12773.7 CBY12800.1 - 1 9.5 13.0 0.26 11.4 8.8 2.2 2 0 0 2 2 2 0 Double zinc ribbon EF-hand_7 PF13499.6 CBY12801.1 - 0.0019 18.6 6.2 0.0034 17.8 0.1 3.5 2 2 0 2 2 2 1 EF-hand domain pair SF1-HH PF16275.5 CBY12801.1 - 0.056 13.8 0.5 0.056 13.8 0.5 3.1 4 0 0 4 4 4 0 Splicing factor 1 helix-hairpin domain MlaC PF05494.12 CBY12801.1 - 0.064 13.0 2.3 2.8 7.7 0.0 3.3 2 1 0 2 2 2 0 MlaC protein HMG_box_2 PF09011.10 CBY12801.1 - 0.099 13.3 15.6 0.31 11.6 0.9 3.2 3 0 0 3 3 3 0 HMG-box domain EF-hand_6 PF13405.6 CBY12801.1 - 0.12 12.3 1.3 3 8.0 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain PP2C_C PF07830.13 CBY12801.1 - 0.14 12.6 3.6 0.56 10.7 3.6 2.2 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain HMG_box PF00505.19 CBY12801.1 - 0.52 10.8 10.0 4.1 7.9 2.0 3.4 2 0 0 2 2 2 0 HMG (high mobility group) box PT-VENN PF04829.13 CBY12801.1 - 0.9 9.7 2.8 3.7 7.7 0.2 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif GST_N_4 PF17172.4 CBY12801.1 - 2.8 8.7 8.0 3 8.7 0.3 3.4 3 1 0 3 3 3 0 Glutathione S-transferase N-terminal domain PT-VENN PF04829.13 CBY12802.1 - 0.074 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif PT-VENN PF04829.13 CBY12803.1 - 0.019 15.0 10.0 9.3 6.4 0.1 4.8 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif DUF1281 PF06924.11 CBY12803.1 - 0.052 13.1 12.2 1 8.9 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1281) HMG_box_2 PF09011.10 CBY12803.1 - 0.31 11.7 28.3 2.8 8.6 3.1 5.5 4 0 0 4 4 4 0 HMG-box domain Sigma_1s PF02454.16 CBY12803.1 - 3.9 7.5 12.0 10 6.1 0.0 4.4 5 0 0 5 5 5 0 Sigma 1s protein Pkinase PF00069.25 CBY12806.1 - 1.8e-13 50.5 2.1 1.8e-13 50.5 2.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12806.1 - 2.8e-07 30.1 0.1 5.8e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DCP2 PF05026.13 CBY12806.1 - 0.055 13.8 0.2 0.2 12.0 0.2 2.0 1 0 0 1 1 1 0 Dcp2, box A domain SLATT_fungal PF18142.1 CBY12806.1 - 0.16 11.9 0.4 0.62 10.1 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain AAA_lid_3 PF17862.1 CBY12807.1 - 6.3e-09 35.5 1.2 7.8e-09 35.2 0.1 1.7 2 0 0 2 2 2 1 AAA+ lid domain Dimer_Tnp_hAT PF05699.14 CBY12807.1 - 0.00015 21.5 0.2 0.00041 20.1 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region SSP160 PF06933.11 CBY12808.1 - 0.011 13.9 10.1 0.01 14.1 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RIFIN PF02009.16 CBY12808.1 - 0.04 13.8 0.6 0.043 13.7 0.6 1.1 1 0 0 1 1 1 0 Rifin DUF3439 PF11921.8 CBY12808.1 - 0.06 13.3 11.5 0.08 12.9 11.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glycoprotein PF03409.15 CBY12808.1 - 0.095 11.5 11.4 0.097 11.5 11.4 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein ATF7IP_BD PF16788.5 CBY12808.1 - 0.14 12.3 3.0 0.17 12.0 3.0 1.0 1 0 0 1 1 1 0 ATF-interacting protein binding domain Dicty_REP PF05086.12 CBY12808.1 - 0.25 9.3 4.6 0.25 9.3 4.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.11 CBY12808.1 - 0.65 8.0 6.3 0.63 8.1 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen S_100 PF01023.19 CBY12809.1 - 2.5e-07 30.3 0.2 3.5e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 CBY12809.1 - 1.1e-06 29.0 0.5 1.3e-06 28.7 0.5 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY12809.1 - 4.8e-06 26.1 1.1 0.0021 17.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY12809.1 - 5.5e-06 25.6 0.4 9.4e-05 21.7 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBY12809.1 - 1.6e-05 24.7 1.1 2.2e-05 24.2 1.1 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 CBY12809.1 - 0.0019 18.1 0.1 0.0023 17.9 0.1 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 CBY12809.1 - 0.0066 15.9 0.5 0.063 12.8 0.2 2.3 2 0 0 2 2 2 1 EF hand Pkinase PF00069.25 CBY12810.1 - 6e-10 38.9 1.3 5e-09 35.9 0.5 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12810.1 - 1.3e-05 24.6 0.0 2.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Condensation PF00668.20 CBY12812.1 - 5.4e-06 25.3 0.1 2.1e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Condensation domain SLATT_fungal PF18142.1 CBY12814.1 - 0.033 14.2 0.1 0.058 13.4 0.1 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain SHNi-TPR PF10516.9 CBY12816.1 - 0.067 12.7 2.9 4.9 6.7 0.1 3.4 3 0 0 3 3 3 0 SHNi-TPR Rhodanese PF00581.20 CBY12817.1 - 3.9e-11 43.4 0.0 4.3e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain DUF724 PF05266.14 CBY12820.1 - 0.063 13.1 0.4 0.063 13.1 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) WH1 PF00568.23 CBY12821.1 - 1.6e-18 66.7 0.0 2.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CBY12821.1 - 7.6e-08 31.9 0.5 1.4e-07 31.1 0.5 1.5 1 0 0 1 1 1 1 WH2 motif Ran_BP1 PF00638.18 CBY12821.1 - 0.03 14.6 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 RanBP1 domain Hyccin PF09790.9 CBY12822.1 - 2.4e-10 40.0 5.4 6.4e-08 32.1 5.4 2.5 1 1 0 1 1 1 1 Hyccin Birna_VP4 PF01768.16 CBY12822.1 - 0.095 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP4 protein DUF667 PF05018.13 CBY12823.1 - 1.7e-84 282.2 0.5 1.9e-84 282.0 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) SGBP_B_XBD PF18329.1 CBY12823.1 - 0.057 13.4 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain MCM_bind PF09739.9 CBY12824.1 - 0.057 11.9 0.0 0.071 11.6 0.0 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SCO1-SenC PF02630.14 CBY12826.1 - 2.3e-37 127.9 0.0 2.9e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 CBY12826.1 - 0.00059 20.1 0.2 0.0014 18.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like BRICHOS PF04089.14 CBY12826.1 - 0.031 14.5 0.1 0.064 13.5 0.1 1.5 1 0 0 1 1 1 0 BRICHOS domain UPF0154 PF03672.13 CBY12826.1 - 0.054 13.5 0.2 9.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) zf-C2H2 PF00096.26 CBY12827.1 - 0.00056 20.2 7.9 0.071 13.6 0.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_ribbon_SprT PF17283.2 CBY12827.1 - 0.00083 19.2 0.3 0.068 13.1 0.0 2.9 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-C2H2_4 PF13894.6 CBY12827.1 - 0.027 15.3 6.9 3.4 8.8 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Vps39_2 PF10367.9 CBY12830.1 - 0.0063 17.0 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF3450 PF11932.8 CBY12831.1 - 0.0027 17.0 7.0 0.0027 17.0 7.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) SHE3 PF17078.5 CBY12831.1 - 0.015 15.0 17.0 0.031 14.0 17.0 1.5 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Fez1 PF06818.15 CBY12831.1 - 0.018 15.5 16.4 0.018 15.5 16.4 1.6 2 0 0 2 2 2 0 Fez1 V_ATPase_I PF01496.19 CBY12831.1 - 0.082 10.8 9.2 0.098 10.6 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec20 PF03908.13 CBY12831.1 - 0.29 11.1 3.8 0.64 10.0 3.8 1.6 1 0 0 1 1 1 0 Sec20 Spc29 PF17082.5 CBY12831.1 - 0.51 10.1 10.6 0.24 11.2 6.9 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 Mu-like_Pro PF10123.9 CBY12831.1 - 0.96 8.9 10.0 1.2 8.6 9.1 1.5 1 1 0 1 1 1 0 Mu-like prophage I protein DUF848 PF05852.11 CBY12831.1 - 1.6 8.9 11.5 2.9 8.0 11.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Macoilin PF09726.9 CBY12831.1 - 1.7 7.1 13.5 2.5 6.5 13.5 1.2 1 0 0 1 1 1 0 Macoilin family HSBP1 PF06825.12 CBY12831.1 - 1.8 8.5 10.3 0.18 11.6 1.0 3.0 3 0 0 3 3 3 0 Heat shock factor binding protein 1 MCC-bdg_PDZ PF10506.9 CBY12831.1 - 3.4 7.8 8.7 0.94 9.5 4.2 2.3 3 0 0 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4482 PF14818.6 CBY12831.1 - 3.4 8.5 22.8 0.39 11.6 11.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) DUF1515 PF07439.11 CBY12831.1 - 3.5 7.7 9.3 15 5.6 3.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) Exonuc_VII_L PF02601.15 CBY12831.1 - 3.6 7.1 10.2 5.2 6.6 10.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nuc_N PF14448.6 CBY12831.1 - 4.7 7.1 4.9 56 3.7 0.0 3.4 3 1 1 4 4 3 0 Nuclease N terminal ECH_2 PF16113.5 CBY12831.1 - 4.9 6.5 9.9 6.2 6.2 9.4 1.4 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF1664 PF07889.12 CBY12831.1 - 6.2 6.9 14.2 0.67 10.0 7.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HSP70 PF00012.20 CBY12831.1 - 7.9 4.5 15.0 11 4.0 15.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Herpes_UL6 PF01763.16 CBY12831.1 - 9.3 4.6 12.9 1.8 7.0 0.5 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like TMPIT PF07851.13 CBY12831.1 - 9.8 5.3 14.4 15 4.7 14.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein CUB PF00431.20 CBY12833.1 - 6e-07 29.8 0.0 9.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 CUB domain CCDC53 PF10152.9 CBY12834.1 - 0.081 13.3 0.7 0.094 13.1 0.7 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Claudin_2 PF13903.6 CBY12835.1 - 0.0064 16.3 0.2 0.017 14.9 0.1 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CBY12835.1 - 0.011 15.7 1.4 0.092 12.6 1.4 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family CpXC PF14353.6 CBY12836.1 - 0.0095 16.0 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 CpXC protein DUF4200 PF13863.6 CBY12837.1 - 1.5e-14 54.5 3.7 1.5e-14 54.5 3.7 4.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) SRP_SPB PF02978.19 CBY12837.1 - 0.0014 19.2 3.3 0.0095 16.5 3.3 2.5 1 0 0 1 1 1 1 Signal peptide binding domain Baculo_PEP_C PF04513.12 CBY12837.1 - 0.07 13.2 1.1 0.27 11.3 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 CBY12837.1 - 0.31 10.6 6.0 0.12 11.9 0.7 2.5 2 0 0 2 2 2 0 fzo-like conserved region RT_RNaseH_2 PF17919.1 CBY12840.1 - 9.4e-28 96.2 0.0 2.1e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY12840.1 - 1e-27 96.4 0.0 2.2e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY12840.1 - 1.6e-16 60.6 0.0 4.4e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CBY12840.1 - 8.5e-12 45.1 0.0 1.3e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY12840.1 - 1.8e-11 44.0 0.1 4.9e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS240 PF13610.6 CBY12840.1 - 0.00046 20.4 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 DDE domain RVT_thumb PF06817.14 CBY12840.1 - 0.043 13.6 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Reverse transcriptase thumb domain QWRF PF04484.12 CBY12841.1 - 0.16 11.7 2.4 0.22 11.3 2.4 1.2 1 0 0 1 1 1 0 QWRF family DUF4992 PF16383.5 CBY12841.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Kelch_6 PF13964.6 CBY12843.1 - 4.6e-06 26.7 0.1 0.14 12.5 0.0 3.7 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY12843.1 - 0.00011 22.0 0.6 0.0019 18.1 0.0 3.4 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 CBY12843.1 - 0.00035 20.5 0.6 1.7 8.7 0.0 4.4 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY12843.1 - 0.0025 17.8 0.1 0.085 12.9 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CBY12843.1 - 0.011 16.0 0.6 0.68 10.3 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY12843.1 - 0.07 12.7 0.1 3.6 7.3 0.0 3.0 2 0 0 2 2 2 0 Kelch motif Gal-3-0_sulfotr PF06990.11 CBY12845.1 - 2.6e-68 230.8 0.0 3.1e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_3 PF13469.6 CBY12845.1 - 0.002 18.6 0.1 0.004 17.6 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family PHINT_rpt PF14882.6 CBY12845.1 - 0.22 11.8 4.4 7.9 6.8 0.2 3.2 3 0 0 3 3 3 0 Phage-integrase repeat unit DUF1726 PF08351.11 CBY12845.1 - 0.22 11.5 0.7 2.1 8.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) Methyltransf_32 PF13679.6 CBY12846.1 - 3.5e-17 62.8 1.0 5.3e-17 62.2 0.4 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY12846.1 - 1e-05 26.1 0.0 4.5e-05 24.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY12846.1 - 5.3e-05 23.1 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY12846.1 - 0.00022 20.8 0.1 0.00032 20.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CBY12846.1 - 0.00083 20.0 0.0 0.0016 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CBY12846.1 - 0.00088 18.7 0.1 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 CBY12846.1 - 0.002 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBY12846.1 - 0.0086 16.0 0.2 0.02 14.8 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY12846.1 - 0.015 15.9 0.0 0.037 14.7 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain Zn_dep_PLPC PF00882.18 CBY12846.1 - 0.025 14.6 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Zinc dependent phospholipase C CMAS PF02353.20 CBY12846.1 - 0.061 12.6 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 3HCDH_N PF02737.18 CBY12846.1 - 0.072 13.0 0.1 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCMT PF01135.19 CBY12846.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CC2-LZ PF16516.5 CBY12846.1 - 0.41 11.0 5.0 0.59 10.5 0.5 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1664 PF07889.12 CBY12846.1 - 0.91 9.6 3.5 5.6 7.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_M14 PF00246.24 CBY12847.1 - 1.3e-64 218.8 0.0 2.1e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CBY12847.1 - 1.6e-05 24.1 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Dimer_Tnp_hAT PF05699.14 CBY12848.1 - 5.9e-06 26.0 0.2 1.1e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PIEZO PF15917.5 CBY12849.1 - 7.3e-25 87.8 0.5 1.4e-24 86.9 0.5 1.4 1 0 0 1 1 1 1 Piezo Piezo_RRas_bdg PF12166.8 CBY12849.1 - 8.7e-14 51.6 0.6 2e-13 50.4 0.6 1.6 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain AAA PF00004.29 CBY12850.1 - 4.7e-41 140.3 0.0 1.1e-40 139.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY12850.1 - 3.8e-09 36.2 0.0 8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBY12850.1 - 0.00021 21.3 0.1 0.0011 19.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY12850.1 - 0.00029 21.1 0.1 0.031 14.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 CBY12850.1 - 0.0005 20.2 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBY12850.1 - 0.0017 18.8 0.1 0.07 13.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CBY12850.1 - 0.0026 17.0 0.0 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBY12850.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBY12850.1 - 0.0051 17.0 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBY12850.1 - 0.025 14.1 0.0 0.065 12.7 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBY12850.1 - 0.029 14.8 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 CBY12850.1 - 0.033 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBY12850.1 - 0.036 14.3 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBY12850.1 - 0.064 13.0 0.2 0.3 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 CBY12850.1 - 0.092 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 CBY12850.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 CBY12850.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY12850.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sec8_exocyst PF04048.14 CBY12851.1 - 9.1e-12 45.1 0.1 9.1e-12 45.1 0.1 4.3 4 2 0 4 4 4 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CBY12851.1 - 0.0033 16.8 8.4 0.0033 16.8 8.4 2.8 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex ALMT PF11744.8 CBY12851.1 - 0.046 12.5 5.3 0.018 13.9 1.1 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter GLE1 PF07817.13 CBY12851.1 - 0.077 12.2 0.9 0.91 8.7 0.0 3.1 4 0 0 4 4 4 0 GLE1-like protein BLOC1_2 PF10046.9 CBY12851.1 - 0.14 12.5 0.0 0.14 12.5 0.0 4.0 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec8_exocyst PF04048.14 CBY12852.1 - 1.6e-11 44.2 0.1 1.6e-11 44.2 0.1 8.0 10 1 0 10 10 10 2 Sec8 exocyst complex component specific domain SLATT_1 PF18181.1 CBY12852.1 - 1.3 9.0 5.4 0.54 10.2 0.4 3.2 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Vps4_C PF09336.10 CBY12852.1 - 2.2 8.3 4.4 6.1 6.9 0.7 3.3 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain Vps4_C PF09336.10 CBY12853.1 - 0.28 11.2 3.5 3.2 7.8 0.6 3.5 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain CLTH PF10607.9 CBY12854.1 - 2.2e-24 86.0 0.8 3.1e-24 85.5 0.8 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain B9-C2 PF07162.11 CBY12855.1 - 5.7e-26 91.7 0.0 6.4e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF1178 PF06676.11 CBY12857.1 - 0.3 11.5 1.6 0.4 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Mtp PF03821.16 CBY12858.1 - 4.6e-05 23.1 2.4 8.5e-05 22.3 2.4 1.4 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter Shisa PF13908.6 CBY12858.1 - 0.00063 20.0 0.5 0.012 15.9 0.2 2.2 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Patched PF02460.18 CBY12858.1 - 0.0016 16.6 4.2 0.0027 15.9 4.2 1.3 1 0 0 1 1 1 1 Patched family Tmemb_9 PF05434.11 CBY12858.1 - 0.04 13.8 0.4 0.04 13.8 0.4 1.8 2 0 0 2 2 1 0 TMEM9 DUF2207 PF09972.9 CBY12858.1 - 0.047 12.5 0.1 0.047 12.5 0.1 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) OAD_gamma PF04277.13 CBY12858.1 - 0.051 14.2 0.2 0.051 14.2 0.2 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF1418 PF07214.12 CBY12858.1 - 0.12 12.2 6.2 0.14 12.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) EpsG PF14897.6 CBY12858.1 - 0.12 11.6 18.6 0.11 11.7 8.3 2.4 1 1 1 2 2 2 0 EpsG family SHP PF03579.13 CBY12858.1 - 0.17 11.8 5.1 2.8 8.0 0.1 3.5 3 0 0 3 3 3 0 Small hydrophobic protein DUF2569 PF10754.9 CBY12858.1 - 0.22 12.0 0.2 0.22 12.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) Phage_holin_2_4 PF16082.5 CBY12858.1 - 0.24 11.2 0.5 0.69 9.7 0.5 1.8 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like HemY_N PF07219.13 CBY12858.1 - 1.2 9.3 0.0 1.2 9.3 0.0 3.5 3 1 1 4 4 4 0 HemY protein N-terminus DUF2631 PF10939.8 CBY12858.1 - 3 7.8 6.6 3.4 7.6 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) Tubulin PF00091.25 CBY12859.1 - 7.4e-69 231.9 0.0 1.2e-68 231.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY12859.1 - 8.5e-44 148.8 0.1 1.4e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY12859.1 - 7.2e-06 26.3 0.0 1.9e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBY12859.1 - 0.0072 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBY12859.1 - 0.008 15.4 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin like TUDOR PF00567.24 CBY12860.1 - 2.8e-66 221.1 6.6 4.1e-12 46.2 0.0 7.5 7 0 0 7 7 7 7 Tudor domain SMN PF06003.12 CBY12860.1 - 1.7e-11 43.9 12.9 2.8e-05 23.5 0.2 5.4 5 0 0 5 5 5 3 Survival motor neuron protein (SMN) DUF4537 PF15057.6 CBY12860.1 - 2.3e-07 30.8 1.3 0.56 10.2 0.0 4.1 4 0 0 4 4 4 3 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 CBY12860.1 - 0.12 12.3 0.5 1.3 9.0 0.1 2.9 3 0 0 3 3 3 0 Tumour suppressor p53-binding protein-1 Tudor ADAM_spacer1 PF05986.14 CBY12860.1 - 0.13 12.3 0.0 22 5.1 0.0 3.3 3 0 0 3 3 3 0 ADAM-TS Spacer 1 DND1_DSRM PF14709.7 CBY12861.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 FAM163 PF15069.6 CBY12862.1 - 0.0068 16.9 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 FAM163 family Git3 PF11710.8 CBY12862.1 - 0.16 11.7 0.3 0.24 11.1 0.3 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DDE_Tnp_1_7 PF13843.6 CBY12863.1 - 6.5e-23 81.6 0.0 1e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 CBY12863.1 - 0.0023 18.7 10.3 0.14 13.0 10.5 2.8 1 1 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon DDE_Tnp_1 PF01609.21 CBY12863.1 - 0.076 12.6 0.2 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE domain zf-AN1 PF01428.16 CBY12863.1 - 0.68 10.1 6.2 0.21 11.8 2.8 2.0 1 1 0 1 1 1 0 AN1-like Zinc finger zf-B_box PF00643.24 CBY12863.1 - 3.7 7.8 8.1 5.2 7.3 2.6 2.5 1 1 1 2 2 2 0 B-box zinc finger PAN_4 PF14295.6 CBY12864.1 - 0.00061 19.6 0.2 0.00077 19.3 0.2 1.3 1 0 0 1 1 1 1 PAN domain UCH PF00443.29 CBY12865.1 - 1.1e-30 107.0 0.6 1.5e-30 106.6 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY12865.1 - 1.8e-08 34.4 0.7 3e-08 33.7 0.3 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PQQ PF01011.21 CBY12867.1 - 0.001 18.9 1.5 0.0046 16.8 0.4 2.5 1 1 1 2 2 2 1 PQQ enzyme repeat Clp1 PF06807.14 CBY12867.1 - 0.14 12.6 0.1 0.24 11.8 0.1 1.3 1 1 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 BCD PF15461.6 CBY12869.1 - 0.001 18.6 1.2 0.0017 17.9 1.0 1.5 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase PIG-Y PF15159.6 CBY12869.1 - 1.3 10.0 7.1 4.6 8.2 7.1 1.9 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y HLH PF00010.26 CBY12871.1 - 5.1e-13 48.8 3.2 5.1e-13 48.8 3.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MAGE PF01454.19 CBY12871.1 - 0.12 12.1 0.2 0.12 12.1 0.2 1.5 2 0 0 2 2 2 0 MAGE family PDEase_I PF00233.19 CBY12872.1 - 4.4e-72 242.6 2.1 6.4e-72 242.1 2.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pkinase PF00069.25 CBY12874.1 - 1.7e-37 129.2 0.1 1.5e-28 99.9 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12874.1 - 1.2e-19 70.6 0.0 1.1e-16 60.9 0.0 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY12874.1 - 0.015 14.6 0.3 2.4 7.4 0.0 2.6 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 CBY12874.1 - 0.023 14.0 0.0 0.23 10.8 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bap31_Bap29_C PF18035.1 CBY12874.1 - 0.63 10.1 4.9 0.12 12.4 0.9 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain RRM_1 PF00076.22 CBY12875.1 - 1.1e-41 140.5 0.0 2e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY12875.1 - 2.2e-06 27.7 0.0 0.009 16.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CBY12875.1 - 2e-05 24.2 0.0 0.0051 16.4 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CBY12875.1 - 0.019 14.6 0.3 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 CBY12875.1 - 0.041 13.9 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Peptidase_C48 PF02902.19 CBY12876.1 - 7.1e-19 68.5 0.7 1.3e-17 64.4 0.7 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RRM_1 PF00076.22 CBY12877.1 - 6.6e-16 57.9 0.0 1.2e-07 31.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OCRE PF17780.1 CBY12877.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 OCRE domain Limkain-b1 PF11608.8 CBY12877.1 - 0.033 14.2 0.0 5.7 7.1 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 Med9 PF07544.13 CBY12877.1 - 0.078 13.1 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 EF-hand_7 PF13499.6 CBY12878.1 - 2.1e-11 44.1 2.0 2.1e-11 44.1 2.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY12878.1 - 6.7e-11 40.9 12.6 6e-07 28.6 1.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY12878.1 - 1.8e-10 39.8 4.6 5.3e-05 22.8 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CBY12878.1 - 8.3e-09 35.2 1.1 0.0004 20.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY12878.1 - 5.5e-07 28.8 13.0 0.0013 18.1 1.0 3.2 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 CBY12878.1 - 4.1e-05 23.9 0.2 4.1e-05 23.9 0.2 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CBY12878.1 - 0.15 12.0 1.1 0.96 9.3 0.2 2.1 1 1 1 2 2 2 0 Caleosin related protein Snf7 PF03357.21 CBY12879.1 - 1.6e-31 109.2 23.3 1.6e-31 109.2 23.3 1.9 1 1 1 2 2 2 1 Snf7 POR PF01558.18 CBY12879.1 - 0.22 11.6 2.3 0.14 12.2 0.6 1.6 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF2855 PF11017.8 CBY12879.1 - 1.1 8.9 3.9 11 5.7 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) YlqD PF11068.8 CBY12879.1 - 1.2 9.5 16.1 0.31 11.4 10.3 2.2 1 1 1 2 2 2 0 YlqD protein PTPRCAP PF15713.5 CBY12880.1 - 0.19 12.0 7.5 0.23 11.8 7.5 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF3807 PF12720.7 CBY12880.1 - 1.4 9.2 15.5 1.6 9.0 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Apt1 PF10351.9 CBY12880.1 - 1.8 7.4 16.3 1.9 7.3 16.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CBY12880.1 - 2.4 6.3 16.0 2.4 6.3 16.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 CBY12880.1 - 3.3 6.4 9.5 3.6 6.2 9.5 1.0 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.12 CBY12880.1 - 3.8 7.3 11.1 4.8 6.9 11.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CBY12880.1 - 3.8 6.2 11.6 3.9 6.1 11.6 1.0 1 0 0 1 1 1 0 Presenilin CFIA_Pcf11 PF11526.8 CBY12881.1 - 0.076 13.5 0.5 0.076 13.5 0.5 3.3 3 0 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 Zn-C2H2_12 PF18112.1 CBY12881.1 - 0.095 13.2 1.7 13 6.4 0.1 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 CBY12881.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 CBY12881.1 - 1.1 9.2 4.4 20 5.2 1.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Pox_VLTF3 PF04947.14 CBY12882.1 - 0.12 12.1 6.5 0.23 11.2 2.6 2.3 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like Tam41_Mmp37 PF09139.11 CBY12882.1 - 0.3 10.5 4.3 0.19 11.1 2.4 1.6 1 1 1 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial FlgM PF04316.13 CBY12882.1 - 4.8 7.6 8.3 5.6 7.4 5.0 2.8 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM YtxH PF12732.7 CBY12882.1 - 6.7 7.3 6.7 7.6 7.1 3.7 2.4 2 1 0 2 2 2 0 YtxH-like protein Myb_DNA-binding PF00249.31 CBY12883.1 - 0.039 14.2 0.1 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF2894 PF11445.8 CBY12883.1 - 0.21 12.0 2.2 0.4 11.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) HlyIII PF03006.20 CBY12885.1 - 1.1e-60 205.2 21.2 5.1e-60 203.0 21.2 1.8 1 1 0 1 1 1 1 Haemolysin-III related L51_S25_CI-B8 PF05047.16 CBY12886.1 - 5.9e-15 54.9 0.0 7.8e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1894 PF08979.11 CBY12886.1 - 0.081 13.3 0.0 0.49 10.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1894) Rep_N PF08724.10 CBY12886.1 - 0.2 11.4 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Rep protein catalytic domain like DSPc PF00782.20 CBY12887.1 - 7.3e-35 119.7 0.9 1.4e-34 118.8 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 CBY12887.1 - 2.2e-07 30.7 1.2 5e-07 29.5 1.2 1.6 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 CBY12887.1 - 0.0048 16.5 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase G-7-MTase PF12803.7 CBY12888.1 - 0.01 15.0 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Trypsin PF00089.26 CBY12889.1 - 9.3e-14 51.8 0.2 3.1e-12 46.8 0.2 2.8 1 1 0 1 1 1 1 Trypsin Qua1 PF16274.5 CBY12889.1 - 0.055 13.3 1.0 14 5.6 0.1 3.0 2 0 0 2 2 2 0 Qua1 domain TRC8_N PF13705.6 CBY12890.1 - 6e-33 114.5 4.4 6e-33 114.5 4.4 2.1 2 0 0 2 2 2 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 CBY12890.1 - 6.8e-11 42.3 6.1 1.4e-10 41.3 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY12890.1 - 3.7e-09 36.3 4.5 7.9e-09 35.2 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY12890.1 - 8.4e-09 35.6 7.7 3e-08 33.8 7.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBY12890.1 - 8.1e-06 25.6 5.0 8.1e-06 25.6 5.0 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY12890.1 - 6.3e-05 22.6 4.2 0.00014 21.5 4.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBY12890.1 - 0.00017 21.5 2.2 0.00043 20.2 2.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY12890.1 - 0.0005 19.9 4.4 0.00088 19.1 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY12890.1 - 0.00085 19.3 4.3 0.0025 17.8 4.3 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CBY12890.1 - 0.0071 15.9 4.9 0.0071 15.9 4.9 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CBY12890.1 - 0.0087 16.2 4.9 0.055 13.6 4.9 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.6 CBY12890.1 - 0.009 16.0 5.0 0.009 16.0 5.0 1.7 2 0 0 2 2 1 1 zinc-RING finger domain Zf_RING PF16744.5 CBY12890.1 - 0.14 12.3 3.1 0.3 11.2 3.1 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_10 PF16685.5 CBY12890.1 - 0.16 12.2 3.9 0.32 11.2 3.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Fibrillin_U_N PF18193.1 CBY12890.1 - 0.18 11.9 0.2 0.38 10.9 0.2 1.5 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Prok-RING_1 PF14446.6 CBY12890.1 - 0.34 10.9 6.7 0.097 12.6 2.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 CBY12890.1 - 0.34 10.8 4.8 0.61 10.0 4.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 CBY12890.1 - 0.4 11.0 5.6 0.72 10.2 5.6 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 CBY12890.1 - 2.5 8.3 5.3 5 7.3 5.3 1.5 1 0 0 1 1 1 0 RING-variant domain Peptidase_M16 PF00675.20 CBY12891.1 - 1.7e-35 122.2 0.0 2.5e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBY12891.1 - 7.1e-13 49.0 0.0 1.3e-11 44.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain ATP-synt_F PF01990.17 CBY12893.1 - 1e-28 99.5 0.1 1.2e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Nramp PF01566.18 CBY12894.1 - 5.2e-64 216.5 1.7 5.2e-64 216.5 1.7 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Phospholip_A2_1 PF00068.19 CBY12894.1 - 1.7e-10 41.4 10.5 1.7e-10 41.4 10.5 2.2 2 0 0 2 2 2 1 Phospholipase A2 EutH PF04346.12 CBY12894.1 - 0.012 14.8 7.9 0.019 14.2 7.9 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH DUF4659 PF15558.6 CBY12895.1 - 4.2e-09 35.8 112.3 4.2e-09 35.8 112.3 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4659) zf-C3HC4_2 PF13923.6 CBY12896.1 - 0.00064 19.5 13.0 0.00064 19.5 13.0 2.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY12896.1 - 0.0079 16.0 7.7 0.0079 16.0 7.7 2.9 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY12896.1 - 0.047 13.7 11.0 0.047 13.7 11.0 2.7 2 1 0 2 2 2 0 zinc-RING finger domain PWI PF01480.17 CBY12897.1 - 1e-19 70.6 0.0 2.1e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 PWI domain Coilin_N PF15862.5 CBY12897.1 - 0.0015 18.4 44.3 0.0048 16.7 9.5 4.1 1 1 2 3 3 3 1 Coilin N-terminus RNA_pol_Rpb2_6 PF00562.28 CBY12898.1 - 4e-116 388.3 4.1 2e-74 251.0 0.9 2.8 2 1 1 3 3 3 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBY12898.1 - 3e-46 157.5 1.0 4.8e-46 156.8 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CBY12898.1 - 8e-28 96.7 0.1 2.6e-27 95.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CBY12898.1 - 3.1e-22 78.6 0.1 7.9e-22 77.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CBY12898.1 - 9e-18 64.2 0.0 2.2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 CBY12898.1 - 1.1e-13 51.3 4.6 4.3e-13 49.3 4.6 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 CBY12898.1 - 1.6e-06 28.6 0.0 5.3e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 bacHORMA_2 PF18173.1 CBY12898.1 - 0.16 11.8 0.1 0.95 9.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial HORMA domain 2 Somatomedin_B PF01033.17 CBY12899.1 - 0.0012 19.2 22.3 0.0012 19.2 22.3 2.5 2 1 0 2 2 2 1 Somatomedin B domain SAND PF01342.21 CBY12901.1 - 1.1e-21 76.3 1.0 2.2e-21 75.3 1.0 1.5 1 0 0 1 1 1 1 SAND domain CAP PF00188.26 CBY12902.1 - 3.1e-08 34.5 0.6 4.7e-08 33.9 0.6 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_hydro_18 PF00704.28 CBY12903.1 - 7.8e-75 252.5 4.8 1e-74 252.1 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 CBY12903.1 - 4.7e-10 39.5 11.7 4.7e-10 39.5 11.7 2.4 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain TPR_1 PF00515.28 CBY12905.1 - 0.055 13.3 0.2 0.055 13.3 0.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF1931 PF09123.11 CBY12905.1 - 0.067 13.3 0.3 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) TPR_2 PF07719.17 CBY12905.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2852 PF11014.8 CBY12905.1 - 0.11 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF664 PF04978.12 CBY12905.1 - 0.16 12.4 1.1 0.5 10.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF664) ANAPC5 PF12862.7 CBY12905.1 - 0.18 11.9 1.4 2.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 YtxH PF12732.7 CBY12905.1 - 0.61 10.7 8.5 95 3.6 8.5 2.7 1 1 0 1 1 1 0 YtxH-like protein Alanine_zipper PF11839.8 CBY12905.1 - 0.96 9.9 11.2 2.5 8.5 5.8 2.4 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Gluconate_2-dh3 PF13618.6 CBY12905.1 - 1.2 9.3 5.2 1.1 9.5 0.5 2.0 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 TPR_8 PF13181.6 CBY12905.1 - 1.5 9.2 5.4 1.3 9.5 0.2 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 CBY12906.1 - 1.6e-17 63.1 10.8 2.6e-07 30.8 0.5 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY12906.1 - 1.3e-11 44.3 12.7 0.0021 18.4 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY12906.1 - 9e-10 38.6 12.4 0.0032 18.2 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY12906.1 - 7.6e-07 29.3 0.3 0.021 15.1 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY12906.1 - 0.00025 21.3 3.6 5.3 7.6 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type C1_4 PF07975.12 CBY12906.1 - 0.0043 17.3 2.8 0.23 11.7 0.1 3.0 2 1 1 3 3 3 1 TFIIH C1-like domain zf-C2HE PF16278.5 CBY12906.1 - 0.014 15.9 2.7 6.9 7.2 2.8 3.2 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 CBY12906.1 - 0.021 15.0 6.2 13 6.1 0.2 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger PyrI_C PF02748.15 CBY12906.1 - 0.034 14.0 0.7 16 5.5 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain LIM PF00412.22 CBY12906.1 - 0.048 13.9 4.2 0.19 11.9 2.4 2.4 2 1 0 2 2 2 0 LIM domain ADK_lid PF05191.14 CBY12906.1 - 0.065 13.2 2.0 0.069 13.1 0.2 2.1 2 0 0 2 2 1 0 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 CBY12906.1 - 0.092 12.5 0.3 0.092 12.5 0.3 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_UBZ PF18439.1 CBY12906.1 - 0.12 11.9 1.3 3.1 7.5 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 CBY12906.1 - 0.24 11.5 9.9 0.68 10.0 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CBY12906.1 - 2.1 8.7 4.5 60 4.0 4.7 2.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.14 CBY12906.1 - 2.7 8.0 6.8 14 5.7 0.8 3.0 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-TRAF PF02176.18 CBY12906.1 - 3.7 8.3 5.1 2.4 8.9 2.4 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.10 CBY12906.1 - 4.8 7.4 9.8 11 6.2 1.3 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-CHCC PF10276.9 CBY12906.1 - 5.2 7.2 9.2 1.4 9.1 0.6 3.0 3 0 0 3 3 3 0 Zinc-finger domain RAP1 PF07218.11 CBY12906.1 - 6.7 4.9 6.1 11 4.1 6.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Phospholip_A2_1 PF00068.19 CBY12908.1 - 1.4e-17 64.2 7.3 1.4e-17 64.2 7.3 1.6 2 0 0 2 2 2 1 Phospholipase A2 YusW PF14039.6 CBY12909.1 - 0.13 12.8 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 YusW-like protein Zn-ribbon_8 PF09723.10 CBY12911.1 - 0.013 15.6 0.7 0.023 14.8 0.7 1.4 1 0 0 1 1 1 0 Zinc ribbon domain FRG2 PF15315.6 CBY12912.1 - 0.046 13.9 0.2 0.068 13.4 0.2 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 zf-C3HC4_3 PF13920.6 CBY12916.1 - 6e-05 22.8 8.0 0.00017 21.4 8.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY12916.1 - 8.8e-05 22.4 5.8 0.0002 21.3 5.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY12916.1 - 0.00036 20.4 9.2 0.0013 18.6 9.5 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY12916.1 - 0.00062 20.0 12.3 0.0024 18.2 12.4 2.0 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY12916.1 - 0.0013 18.5 9.1 0.0034 17.2 9.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY12916.1 - 0.0049 16.7 10.0 0.025 14.4 10.1 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Med20 PF08612.11 CBY12916.1 - 0.019 14.3 1.1 0.027 13.8 0.4 1.5 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex zf-C3HC4_2 PF13923.6 CBY12916.1 - 0.022 14.6 7.5 0.022 14.6 7.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 CBY12916.1 - 0.036 14.5 2.9 0.079 13.4 2.9 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 FYVE PF01363.21 CBY12916.1 - 0.037 14.1 5.8 0.1 12.7 5.8 1.8 1 0 0 1 1 1 0 FYVE zinc finger Acyl-thio_N PF12590.8 CBY12916.1 - 0.61 10.7 3.5 0.39 11.3 1.3 1.7 2 0 0 2 2 2 0 Acyl-ATP thioesterase zf-rbx1 PF12678.7 CBY12916.1 - 1.6 9.0 9.8 6.4 7.2 9.6 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain Biotin_carb_C PF02785.19 CBY12920.1 - 4.4e-08 33.2 0.0 1.2e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain FAD_SOX PF18371.1 CBY12921.1 - 0.049 14.0 0.1 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase RT_RNaseH_2 PF17919.1 CBY12922.1 - 1.8e-30 104.9 0.1 2.7e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY12922.1 - 1e-27 96.4 0.1 1.6e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 CBY12922.1 - 0.049 13.5 0.1 0.88 9.4 0.1 2.2 1 1 0 1 1 1 0 Reverse transcriptase thumb domain DUF3914 PF13053.6 CBY12922.1 - 0.098 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) RT_RNaseH_2 PF17919.1 CBY12923.1 - 5.1e-10 39.3 0.0 7e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_pol_viral_C PF00336.18 CBY12923.1 - 0.00046 19.7 0.0 0.00046 19.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Lactamase_B_6 PF16661.5 CBY12923.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain adh_short_C2 PF13561.6 CBY12925.1 - 4.8e-56 189.9 0.4 6.9e-56 189.4 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY12925.1 - 1.8e-54 184.2 1.1 2.3e-54 183.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY12925.1 - 1.6e-12 47.7 0.4 2.3e-12 47.2 0.4 1.1 1 0 0 1 1 1 1 KR domain Orthopox_B11R PF07033.11 CBY12925.1 - 0.17 11.7 0.5 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Orthopoxvirus B11R protein Fic_N PF13784.6 CBY12926.1 - 0.19 11.8 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 Fic/DOC family N-terminal Gp_dh_C PF02800.20 CBY12928.1 - 1.3e-61 206.8 0.3 1.9e-61 206.3 0.3 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBY12928.1 - 5.4e-34 116.6 0.1 1.2e-33 115.4 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBY12928.1 - 0.00073 19.7 1.6 0.023 14.8 0.5 3.3 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus ACT_4 PF13291.6 CBY12928.1 - 0.023 15.3 0.0 0.065 13.8 0.0 1.8 1 0 0 1 1 1 0 ACT domain FDX-ACB PF03147.14 CBY12928.1 - 0.077 13.4 0.3 0.27 11.7 0.2 1.9 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain 2-Hacid_dh_C PF02826.19 CBY12928.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asparaginase_2 PF01112.18 CBY12929.1 - 8.3e-82 274.6 5.4 9.8e-82 274.4 5.4 1.0 1 0 0 1 1 1 1 Asparaginase zf-RING_2 PF13639.6 CBY12930.1 - 9.2e-10 38.7 6.7 1.5e-09 38.1 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY12930.1 - 9.2e-08 31.8 6.6 1.7e-07 30.9 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY12930.1 - 8.8e-07 28.8 4.3 1.8e-06 27.9 4.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY12930.1 - 1.6e-06 28.3 5.6 3.7e-06 27.1 5.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY12930.1 - 7.3e-06 25.8 8.1 1.2e-05 25.1 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY12930.1 - 1.5e-05 24.8 7.4 2.7e-05 24.0 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY12930.1 - 1.9e-05 24.4 5.5 3.5e-05 23.6 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY12930.1 - 0.00015 21.6 5.3 0.00079 19.2 5.0 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 CtIP_N PF10482.9 CBY12930.1 - 0.0013 18.8 7.3 0.0013 18.8 7.3 2.9 2 1 1 3 3 3 1 Tumour-suppressor protein CtIP N-terminal domain zf-Nse PF11789.8 CBY12930.1 - 0.0047 16.7 2.7 0.011 15.5 2.7 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DivIC PF04977.15 CBY12930.1 - 0.011 15.4 10.0 0.24 11.2 0.3 2.9 2 1 1 3 3 3 0 Septum formation initiator zf-RING_4 PF14570.6 CBY12930.1 - 0.015 15.1 2.8 0.038 13.8 2.8 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain HALZ PF02183.18 CBY12930.1 - 0.021 15.0 10.2 1.5 9.1 1.6 3.6 2 2 1 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 CBY12930.1 - 0.024 14.7 11.8 0.52 10.5 0.8 2.8 2 1 0 2 2 2 0 bZIP transcription factor zf-ANAPC11 PF12861.7 CBY12930.1 - 0.032 14.3 2.8 0.13 12.4 2.7 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger ZapB PF06005.12 CBY12930.1 - 0.037 14.5 13.6 0.34 11.4 0.1 3.0 2 1 1 3 3 3 0 Cell division protein ZapB NRBF2 PF08961.10 CBY12930.1 - 0.085 12.4 12.2 0.099 12.2 4.7 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator JIP_LZII PF16471.5 CBY12930.1 - 0.1 12.8 0.9 0.1 12.8 0.9 2.8 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II zf-RING_6 PF14835.6 CBY12930.1 - 0.16 11.9 1.2 0.3 11.0 1.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CBY12930.1 - 0.46 10.6 5.2 1.2 9.3 5.2 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 DUF4407 PF14362.6 CBY12930.1 - 0.52 9.6 4.7 0.78 9.0 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 CBY12930.1 - 0.63 10.4 7.0 2.8 8.3 0.9 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family zf-C3HC4_4 PF15227.6 CBY12930.1 - 0.76 10.0 4.8 2.7 8.2 4.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3450 PF11932.8 CBY12930.1 - 1.1 8.5 7.8 2.4 7.4 7.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Cep57_CLD_2 PF14197.6 CBY12930.1 - 1.1 9.3 13.0 10 6.3 0.6 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 CBY12930.1 - 8.1 6.5 8.3 14 5.8 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) EGF_CA PF07645.15 CBY12931.1 - 7.2e-11 42.1 27.0 2.4e-07 30.8 14.2 2.6 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.7 CBY12931.1 - 4.5e-09 36.4 31.8 0.00023 21.3 6.7 2.4 2 0 0 2 2 2 2 EGF domain cEGF PF12662.7 CBY12931.1 - 0.00021 21.1 22.3 0.00073 19.4 3.1 2.9 2 1 0 2 2 2 2 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CBY12931.1 - 0.025 14.9 21.5 0.37 11.1 2.3 2.6 2 0 0 2 2 2 0 Pvs28 EGF domain EGF PF00008.27 CBY12931.1 - 0.054 13.8 1.2 0.054 13.8 1.2 3.6 3 2 0 3 3 3 0 EGF-like domain EGF_MSP1_1 PF12946.7 CBY12931.1 - 0.12 12.4 19.1 0.61 10.2 2.1 2.5 2 0 0 2 2 2 0 MSP1 EGF domain 1 hEGF PF12661.7 CBY12931.1 - 0.14 12.8 0.5 0.14 12.8 0.5 4.1 5 1 0 5 5 5 0 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY12931.1 - 1.1 9.6 29.7 2.1 8.7 3.5 3.4 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site Neur_chan_LBD PF02931.23 CBY12932.1 - 4.8e-52 176.5 3.8 7.7e-52 175.9 3.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY12932.1 - 1.3e-17 64.7 4.6 2e-17 64.1 4.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4131 PF13567.6 CBY12932.1 - 1 9.0 2.8 1.4 8.6 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 CBY12933.1 - 9.7e-76 254.6 0.0 1.4e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12933.1 - 1.3e-40 139.3 0.0 1.9e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 CBY12933.1 - 1.7e-12 47.8 0.1 3.4e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 CBY12933.1 - 7.9e-08 31.9 0.0 1.7e-07 30.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBY12933.1 - 0.0026 17.4 0.1 0.0059 16.2 0.1 1.5 1 1 0 1 1 1 1 RIO1 family ABC1 PF03109.16 CBY12933.1 - 0.0058 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Haspin_kinase PF12330.8 CBY12933.1 - 0.015 14.3 0.1 0.028 13.4 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 CBY12933.1 - 0.016 14.1 0.0 0.034 13.0 0.0 1.4 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 CBY12933.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY12933.1 - 0.081 12.8 0.2 0.92 9.4 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_8 PF13855.6 CBY12936.1 - 1.4e-35 120.8 13.7 5.8e-13 48.4 0.7 4.3 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY12936.1 - 2.7e-18 65.7 15.9 4e-05 23.9 2.4 5.5 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY12936.1 - 2.1e-12 47.1 0.1 2.7e-06 27.4 0.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBY12936.1 - 5.7e-12 44.4 11.8 0.023 15.2 0.3 8.1 8 0 0 8 8 8 3 Leucine Rich Repeat ig PF00047.25 CBY12936.1 - 2.4e-06 27.6 0.7 5.1e-06 26.6 0.7 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 CBY12936.1 - 3.2e-06 27.6 0.5 1e-05 26.0 0.5 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 CBY12936.1 - 3.4e-05 23.4 1.3 0.19 11.2 0.3 2.6 2 1 1 3 3 3 2 Leucine-rich repeat V-set PF07686.17 CBY12936.1 - 8.9e-05 22.6 0.2 0.00024 21.2 0.2 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 CBY12936.1 - 0.00037 20.5 0.2 0.00076 19.5 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY12936.1 - 0.0012 19.2 0.3 0.0032 17.8 0.3 1.7 1 0 0 1 1 1 1 Immunoglobulin domain C2-set PF05790.15 CBY12936.1 - 0.015 15.5 0.1 0.059 13.6 0.1 2.1 1 1 0 1 1 1 0 Immunoglobulin C2-set domain LRR_6 PF13516.6 CBY12936.1 - 0.11 12.6 20.3 4.3 7.6 0.1 7.1 9 0 0 9 9 9 0 Leucine Rich repeat Astacin PF01400.24 CBY12937.1 - 7.2e-22 77.9 0.5 8.6e-22 77.7 0.5 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF1479 PF07350.12 CBY12937.1 - 0.092 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) adh_short PF00106.25 CBY12938.1 - 4e-51 173.3 1.6 4.9e-51 173.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY12938.1 - 1.3e-35 123.0 0.4 1.7e-35 122.7 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY12938.1 - 6.9e-10 39.1 1.7 8.3e-10 38.9 0.9 1.4 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 CBY12938.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CBY12938.1 - 0.019 14.9 0.6 0.035 14.0 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF155 PF02582.14 CBY12938.1 - 0.025 14.7 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 ApbA PF02558.16 CBY12938.1 - 0.027 14.1 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 CBY12938.1 - 0.035 13.4 1.3 0.054 12.8 1.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 CBY12938.1 - 0.056 14.1 0.1 0.15 12.8 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain OKR_DC_1_N PF03709.15 CBY12938.1 - 0.14 12.4 0.0 6.9 7.0 0.0 2.7 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain SieB PF14163.6 CBY12940.1 - 0.14 11.7 2.9 1.3 8.5 0.0 3.0 3 0 0 3 3 3 0 Super-infection exclusion protein B GWT1 PF06423.12 CBY12940.1 - 0.22 11.7 6.3 0.21 11.7 3.3 2.5 2 1 0 2 2 2 0 GWT1 DUF2975 PF11188.8 CBY12940.1 - 0.31 10.9 0.1 0.31 10.9 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) zf-AN1 PF01428.16 CBY12942.1 - 4.3e-10 39.6 7.4 6.5e-10 39.0 7.4 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger FTHFS PF01268.19 CBY12943.1 - 2.4e-259 861.2 0.1 2.4e-259 861.2 0.1 1.3 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CBY12943.1 - 8.4e-64 213.7 0.3 8.4e-64 213.7 0.3 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBY12943.1 - 6.8e-34 116.6 0.8 1.3e-33 115.7 0.8 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_hydro_47 PF01532.20 CBY12944.1 - 1.2e-120 403.5 0.0 1.2e-120 403.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Trypsin PF00089.26 CBY12945.1 - 1.3e-30 106.8 0.0 2e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin VWA PF00092.28 CBY12945.1 - 0.00032 21.0 1.1 0.00068 19.9 0.4 1.9 1 1 1 2 2 2 1 von Willebrand factor type A domain TMEM154 PF15102.6 CBY12945.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family VWA_2 PF13519.6 CBY12945.1 - 0.028 15.1 0.1 0.1 13.3 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain CREPT PF16566.5 CBY12947.1 - 0.0069 16.6 2.1 0.0072 16.5 2.1 1.1 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DUF5401 PF17380.2 CBY12947.1 - 0.0085 14.2 3.0 0.0082 14.3 3.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5401) SesA PF17107.5 CBY12947.1 - 0.04 14.1 2.2 0.041 14.1 2.2 1.0 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPD52 PF04201.15 CBY12948.1 - 6.2e-20 71.4 0.7 7.9e-20 71.1 0.7 1.1 1 0 0 1 1 1 1 Tumour protein D52 family Malate_DH PF12434.8 CBY12948.1 - 9.2 6.4 6.8 3.1 7.9 0.4 2.3 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Pkinase PF00069.25 CBY12949.1 - 7.4e-62 209.1 0.0 1.1e-61 208.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12949.1 - 7.5e-33 113.9 0.0 1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.9 CBY12949.1 - 0.0016 19.0 0.7 0.0036 17.9 0.7 1.6 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Dus PF01207.17 CBY12949.1 - 0.019 14.1 0.2 0.031 13.4 0.2 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) APH PF01636.23 CBY12949.1 - 0.2 11.5 0.0 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family GTP_EFTU PF00009.27 CBY12950.1 - 1.4e-65 220.5 0.0 2.6e-65 219.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CBY12950.1 - 2.8e-33 114.3 0.0 2.4e-32 111.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CBY12950.1 - 6e-22 77.5 0.0 1.4e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CBY12950.1 - 2e-13 50.2 0.0 4.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CBY12950.1 - 2.4e-10 40.7 0.1 9.4e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY12950.1 - 1.1e-05 25.5 0.1 2.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 CBY12950.1 - 0.098 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SDA1 PF05285.12 CBY12951.1 - 1e-55 189.6 47.1 3e-31 109.1 31.7 3.3 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 CBY12951.1 - 3.2e-15 56.2 0.6 1.5e-14 54.0 0.0 2.5 3 0 0 3 3 3 1 NUC130/3NT domain Metallophos PF00149.28 CBY12953.1 - 4.9e-33 115.3 0.0 7.4e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 CBY12953.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Prefoldin PF02996.17 CBY12954.1 - 4.6e-29 100.8 1.6 5.8e-29 100.4 0.8 1.6 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 CBY12954.1 - 0.0014 18.6 2.2 0.47 10.4 0.2 2.3 1 1 1 2 2 2 2 Prefoldin subunit Laminin_II PF06009.12 CBY12954.1 - 0.015 15.4 0.9 0.46 10.5 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II CdvA PF18822.1 CBY12954.1 - 0.043 13.7 1.5 3.4 7.5 0.1 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Spectrin PF00435.21 CBY12954.1 - 0.08 13.4 0.8 0.8 10.2 0.1 2.4 2 1 0 2 2 2 0 Spectrin repeat YscO PF07321.12 CBY12954.1 - 0.13 12.2 2.0 2.3 8.1 0.2 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO Cupin_4 PF08007.12 CBY12955.1 - 1.3e-20 74.1 0.2 1.9e-20 73.6 0.2 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 CBY12955.1 - 0.02 14.6 0.5 0.1 12.3 0.1 2.3 1 1 1 3 3 3 0 Cupin-like domain Cupin_1 PF00190.22 CBY12955.1 - 0.051 13.2 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Fer4 PF00037.27 CBY12956.1 - 7.8e-16 57.1 16.6 2.8e-09 36.4 4.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CBY12956.1 - 1.4e-13 51.2 11.1 2.1e-13 50.6 11.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CBY12956.1 - 5.1e-12 46.5 6.0 1.1e-05 26.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CBY12956.1 - 1.8e-11 44.0 31.9 2.5e-07 30.7 12.0 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBY12956.1 - 1.2e-10 41.3 20.6 3.4e-07 30.3 12.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBY12956.1 - 1.5e-09 37.9 10.6 2.3e-09 37.3 10.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBY12956.1 - 3.2e-09 37.1 3.5 0.00017 22.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBY12956.1 - 2.1e-08 33.9 18.2 0.00025 21.0 5.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CBY12956.1 - 2.6e-07 30.3 12.8 0.0016 18.4 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CBY12956.1 - 1e-06 28.8 10.5 0.00024 21.4 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBY12956.1 - 2.2e-05 24.9 11.4 0.018 15.6 1.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 CBY12956.1 - 0.0038 17.7 13.8 0.35 11.4 3.8 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 CBY12956.1 - 0.0081 16.4 7.9 0.22 11.7 0.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 CBY12956.1 - 0.0087 16.9 17.4 0.038 14.9 4.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 CBY12956.1 - 0.014 15.6 5.4 1.2 9.4 0.5 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ETF_QO PF05187.13 CBY12956.1 - 0.024 14.8 4.1 0.096 12.8 0.2 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CBY12956.1 - 0.45 11.4 11.9 1.8 9.5 1.8 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Metallophos PF00149.28 CBY12957.1 - 8.7e-14 52.5 0.1 1.6e-13 51.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBY12957.1 - 0.0012 19.0 0.0 0.004 17.4 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Adaptin_N PF01602.20 CBY12958.1 - 5.3e-53 180.4 0.4 6.6e-53 180.1 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region B2-adapt-app_C PF09066.10 CBY12958.1 - 1.9e-28 98.8 0.1 8.4e-28 96.7 0.0 2.0 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Alpha_adaptinC2 PF02883.20 CBY12958.1 - 3.5e-09 37.0 0.8 1.5e-08 35.0 0.4 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.6 CBY12958.1 - 1.1e-05 25.8 0.8 0.16 12.4 0.0 2.5 1 1 0 2 2 2 2 HEAT repeats Cnd3 PF12719.7 CBY12958.1 - 5.3e-05 22.6 0.2 8.3e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 CBY12958.1 - 0.007 16.4 1.1 0.077 13.0 1.8 2.0 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 SHE3 PF17078.5 CBY12958.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Mistic PF11458.8 CBY12958.1 - 1.2 9.1 3.1 16 5.6 0.1 2.7 2 0 0 2 2 2 0 Membrane-integrating protein Mistic Adaptin_N PF01602.20 CBY12959.1 - 2.1e-79 267.5 2.8 2.6e-79 267.2 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBY12959.1 - 8.8e-63 211.2 0.9 8.8e-63 211.2 0.9 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY12959.1 - 2.9e-17 62.8 0.6 1.5e-06 28.5 0.0 3.8 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.22 CBY12959.1 - 4.5e-13 48.2 4.4 0.00082 19.4 0.0 4.6 4 0 0 4 4 4 3 HEAT repeat Arm PF00514.23 CBY12959.1 - 1e-08 34.9 0.2 0.00023 21.1 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CBY12959.1 - 1.6e-05 25.3 0.2 2.2 8.9 0.0 3.8 3 0 0 3 3 3 2 HEAT-like repeat RTP1_C1 PF10363.9 CBY12959.1 - 0.0001 22.4 0.0 0.018 15.2 0.0 3.2 1 1 1 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 CBY12959.1 - 0.00035 20.6 1.1 0.043 13.8 0.0 3.1 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central DNA_alkylation PF08713.11 CBY12959.1 - 0.0015 18.2 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 DNA alkylation repair enzyme Arm_2 PF04826.13 CBY12959.1 - 0.0059 16.1 0.1 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 Armadillo-like Phage_TAC_12 PF12363.8 CBY12959.1 - 0.01 16.3 0.5 1.9 8.9 0.2 2.5 2 0 0 2 2 2 1 Phage tail assembly chaperone protein, TAC TIP120 PF08623.10 CBY12959.1 - 0.017 14.9 2.5 2.2 8.0 0.1 2.7 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) API5 PF05918.11 CBY12959.1 - 0.02 13.7 0.3 1.1 8.0 0.0 2.3 1 1 1 2 2 2 0 Apoptosis inhibitory protein 5 (API5) CLASP_N PF12348.8 CBY12959.1 - 0.02 14.4 0.2 0.21 11.1 0.1 2.6 1 1 1 2 2 2 0 CLASP N terminal RasGEF_N_2 PF14663.6 CBY12959.1 - 0.045 14.1 0.2 5.9 7.3 0.0 3.2 2 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2200 PF09966.9 CBY12959.1 - 0.069 13.3 0.5 14 5.9 0.0 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2200) PsbP PF01789.16 CBY12959.1 - 0.14 12.3 0.2 0.67 10.1 0.1 2.0 2 0 0 2 2 2 0 PsbP fn2 PF00040.19 CBY12960.1 - 1e-07 32.1 4.8 2.4e-07 30.9 4.8 1.7 1 0 0 1 1 1 1 Fibronectin type II domain Sulfotransfer_2 PF03567.14 CBY12961.1 - 0.027 14.4 0.7 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Sulfotransferase family SMP_2 PF10144.9 CBY12962.1 - 0.08 12.6 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin PfkB PF00294.24 CBY12963.1 - 7.8e-33 114.1 0.2 9.5e-33 113.8 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Cyclin_C PF02984.19 CBY12965.1 - 3.2e-14 53.0 0.2 4e-14 52.7 0.2 1.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Lectin_C PF00059.21 CBY12966.1 - 4.6e-20 72.4 21.5 2.8e-08 34.5 0.8 5.6 5 0 0 5 5 5 4 Lectin C-type domain Xlink PF00193.17 CBY12966.1 - 0.0011 19.3 1.5 0.011 16.0 0.1 3.3 4 0 0 4 4 4 1 Extracellular link domain Nop14 PF04147.12 CBY12966.1 - 0.028 12.6 3.0 0.038 12.2 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 CBY12966.1 - 0.27 11.2 5.7 0.55 10.3 5.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 CBY12966.1 - 1 9.0 3.9 3 7.5 3.9 1.7 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 CBY12966.1 - 2.1 7.4 13.9 3.6 6.6 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 CBY12966.1 - 4 7.9 17.2 51 4.3 16.4 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MGAT2 PF05060.14 CBY12967.1 - 1.4e-105 353.2 0.8 1.7e-105 352.9 0.8 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) RIFIN PF02009.16 CBY12969.1 - 0.023 14.6 0.3 0.037 13.9 0.3 1.2 1 0 0 1 1 1 0 Rifin IPK PF03770.16 CBY12970.1 - 4.3e-22 78.9 0.3 1.7e-21 77.0 0.3 1.9 1 1 0 1 1 1 1 Inositol polyphosphate kinase RecG_N PF17190.4 CBY12972.1 - 0.95 10.2 5.8 0.57 11.0 0.2 3.0 2 2 1 3 3 3 0 RecG N-terminal helical domain Ion_trans_2 PF07885.16 CBY12973.1 - 1.6e-28 98.5 24.1 9.9e-15 54.3 9.2 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CBY12973.1 - 3.9e-09 36.1 10.6 6e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Ion transport protein ANAPC16 PF17256.2 CBY12974.1 - 0.13 12.7 0.2 0.13 12.7 0.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 16 Baculo_PEP_C PF04513.12 CBY12974.1 - 1.3 9.1 9.1 0.83 9.7 0.1 3.5 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 CBY12974.1 - 9.8 6.5 10.1 0.7 10.2 1.0 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TPH PF13868.6 CBY12975.1 - 1.6e-10 40.0 115.5 1.6e-10 40.0 115.5 2.4 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain MRP-S32 PF10210.9 CBY12975.1 - 0.055 14.0 0.8 0.055 14.0 0.8 5.2 4 3 3 7 7 7 0 Mitochondrial 28S ribosomal protein S32 Pkinase PF00069.25 CBY12976.1 - 1.8e-72 243.9 0.0 2e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12976.1 - 2.3e-36 125.4 0.0 3e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY12976.1 - 0.0017 17.4 0.1 0.026 13.5 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY12976.1 - 0.0033 17.4 0.0 0.0098 15.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY12976.1 - 0.058 12.5 0.1 0.17 10.9 0.0 1.7 1 1 1 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.6 CBY12976.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like DUF1145 PF06611.12 CBY12977.1 - 1.2 9.1 9.7 0.096 12.7 4.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) zf-RING_5 PF14634.6 CBY12978.1 - 1.4e-05 24.9 11.3 1.4e-05 24.9 11.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain ZapB PF06005.12 CBY12978.1 - 0.00012 22.4 0.4 0.00017 21.9 0.4 1.2 1 0 0 1 1 1 1 Cell division protein ZapB zf-RING_2 PF13639.6 CBY12978.1 - 0.0016 18.7 10.8 0.0016 18.7 10.8 2.2 2 0 0 2 2 2 1 Ring finger domain CASP_C PF08172.12 CBY12978.1 - 0.0033 16.8 0.4 0.0037 16.6 0.4 1.1 1 0 0 1 1 1 1 CASP C terminal TolA_bind_tri PF16331.5 CBY12978.1 - 0.0063 16.6 8.9 0.011 15.8 8.9 1.3 1 0 0 1 1 1 1 TolA binding protein trimerisation Rootletin PF15035.6 CBY12978.1 - 0.0073 16.4 2.1 0.0086 16.1 2.1 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.21 CBY12978.1 - 0.0079 16.3 1.5 0.0079 16.3 1.5 1.7 2 0 0 2 2 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CBY12978.1 - 0.0095 16.4 3.5 0.021 15.3 3.5 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Spc24 PF08286.11 CBY12978.1 - 0.02 15.2 0.8 0.031 14.5 0.8 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 zf-RING_UBOX PF13445.6 CBY12978.1 - 0.029 14.4 9.4 0.079 13.0 9.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY12978.1 - 0.034 14.0 10.3 0.034 14.0 10.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.12 CBY12978.1 - 0.046 14.4 1.9 0.046 14.4 1.9 1.6 2 0 0 2 2 1 0 SlyX MCU PF04678.13 CBY12978.1 - 0.06 13.4 0.1 0.076 13.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter ApoLp-III PF07464.11 CBY12978.1 - 0.072 13.2 0.9 0.11 12.6 0.9 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) FlaC_arch PF05377.11 CBY12978.1 - 0.1 13.0 1.8 1.8 9.0 1.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 CBY12978.1 - 0.13 12.1 2.8 0.23 11.4 2.8 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 CBY12978.1 - 0.26 11.4 6.9 0.14 12.3 3.7 2.0 1 1 1 2 2 2 0 Basic region leucine zipper DUF3450 PF11932.8 CBY12978.1 - 0.44 9.8 5.4 0.59 9.4 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FYVE PF01363.21 CBY12978.1 - 0.46 10.6 19.9 0.041 14.0 12.5 2.3 1 1 1 2 2 2 0 FYVE zinc finger DUF3552 PF12072.8 CBY12978.1 - 0.46 9.9 5.0 0.66 9.4 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DivIC PF04977.15 CBY12978.1 - 0.7 9.7 6.3 1.1 9.0 6.3 1.3 1 0 0 1 1 1 0 Septum formation initiator zf-C3HC4_2 PF13923.6 CBY12978.1 - 8.9 6.3 18.0 9.2 6.2 12.7 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hamartin PF04388.12 CBY12979.1 - 0.053 12.2 2.1 0.054 12.2 2.1 1.0 1 0 0 1 1 1 0 Hamartin protein Mucin PF01456.17 CBY12979.1 - 1 9.3 17.2 1.5 8.8 17.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF5305 PF17231.2 CBY12979.1 - 3.9 6.8 8.9 17 4.7 9.4 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Kelch_5 PF13854.6 CBY12980.1 - 0.0085 16.1 0.5 0.56 10.3 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 CBY12980.1 - 0.014 15.3 1.8 3.6 7.7 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 CBY12980.1 - 0.38 10.8 1.4 6 7.0 0.1 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY12980.1 - 0.65 10.4 5.2 22 5.5 0.0 3.8 3 1 1 4 4 4 0 Kelch motif Cnd3 PF12719.7 CBY12983.1 - 8.9e-10 38.2 2.2 4.1e-09 36.0 2.2 2.2 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CBY12983.1 - 0.0018 18.6 0.8 0.0018 18.6 0.8 4.6 4 1 1 5 5 5 1 HEAT repeats Cohesin_HEAT PF12765.7 CBY12983.1 - 0.02 15.2 5.2 3.7 7.9 0.5 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 CBY12983.1 - 0.096 13.0 13.7 1.4 9.3 0.2 6.3 7 0 0 7 7 7 0 HEAT repeat Z1 PF10593.9 CBY12983.1 - 6.9 6.1 11.3 1 8.8 1.1 2.7 2 0 0 2 2 2 0 Z1 domain Helicase_C_2 PF13307.6 CBY12985.1 - 1.2e-44 152.5 0.0 2.6e-44 151.4 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBY12985.1 - 9.4e-10 38.4 0.6 9.4e-10 38.4 0.6 1.9 2 0 0 2 2 2 1 DEAD_2 SET PF00856.28 CBY12986.1 - 5.3e-16 59.5 0.0 1.1e-15 58.4 0.0 1.6 1 1 0 1 1 1 1 SET domain LMP PF04778.12 CBY12986.1 - 0.031 14.2 0.9 0.059 13.3 0.9 1.4 1 0 0 1 1 1 0 LMP repeated region Kisspeptin PF15152.6 CBY12987.1 - 1.1 10.1 4.0 1.9 9.3 0.7 3.2 2 0 0 2 2 2 0 Kisspeptin Lyase_1 PF00206.20 CBY12988.1 - 4.3e-08 32.9 0.0 5.6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CBY12989.1 - 1.7e-16 60.5 0.1 2.1e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus A_deamin PF02137.18 CBY12991.1 - 2.2e-28 99.7 0.1 2.6e-28 99.4 0.1 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain RSF PF14876.6 CBY12991.1 - 0.064 12.2 0.3 0.079 11.9 0.3 1.1 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Ank_5 PF13857.6 CBY12993.1 - 4.4e-05 23.7 0.1 0.00011 22.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY12993.1 - 0.041 14.5 0.0 0.16 12.6 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.30 CBY12993.1 - 0.047 14.2 3.4 0.63 10.6 0.1 3.8 5 0 0 5 5 5 0 Ankyrin repeat Ank_4 PF13637.6 CBY12993.1 - 0.12 13.0 0.0 42 4.9 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) polyprenyl_synt PF00348.17 CBY12994.1 - 5.3e-81 271.4 0.4 6.3e-81 271.2 0.4 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.25 CBY12995.1 - 5.2e-63 212.9 0.0 6.4e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY12995.1 - 4.2e-24 85.2 0.0 5.4e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY12995.1 - 5.6e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY12995.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY12995.1 - 0.037 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxidored_q4 PF00507.19 CBY12996.1 - 2.8e-05 24.2 5.2 5.5e-05 23.3 5.0 1.6 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Glyco_hydro_1 PF00232.18 CBY12998.1 - 1.5e-37 129.1 0.1 1.7e-37 128.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 CBY12999.1 - 2.4e-53 181.2 0.1 3.2e-53 180.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 CBY12999.1 - 0.046 13.1 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) RhoGAP PF00620.27 CBY13001.1 - 5.1e-30 104.3 0.3 1.1e-29 103.2 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 CBY13001.1 - 9.4e-19 67.9 0.0 1.9e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain RICTOR_M PF14666.6 CBY13001.1 - 0.052 13.3 0.1 6.2 6.6 0.0 2.8 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Collagen PF01391.18 CBY13002.1 - 1.1e-19 69.9 75.6 8.9e-08 31.8 27.2 3.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Homeodomain PF00046.29 CBY13003.1 - 6.9e-20 70.7 3.4 1.4e-19 69.7 3.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY13003.1 - 2.1e-05 24.3 2.0 3e-05 23.8 0.7 2.0 2 0 0 2 2 2 1 Homeobox KN domain DUF866 PF05907.13 CBY13004.1 - 3.3e-45 153.8 0.7 3.7e-45 153.6 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) RbpA PF13397.6 CBY13004.1 - 0.13 12.9 0.0 0.26 11.9 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase-binding protein FeS PF04060.13 CBY13004.1 - 3.2 7.5 7.0 16 5.3 0.2 2.5 2 0 0 2 2 2 0 Putative Fe-S cluster ELMO_CED12 PF04727.13 CBY13005.1 - 1.3e-15 58.0 0.0 1.7e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Fer2_3 PF13085.6 CBY13006.1 - 2.4e-31 107.9 0.1 4.5e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CBY13006.1 - 3.8e-09 37.0 6.1 3.8e-09 37.0 6.1 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBY13006.1 - 2e-08 34.5 11.4 2e-07 31.3 9.0 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBY13006.1 - 4.2e-08 33.2 3.5 4.2e-08 33.2 3.5 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBY13006.1 - 2.6e-05 24.7 4.9 0.012 16.2 0.1 3.3 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBY13006.1 - 0.018 15.2 8.5 0.018 15.2 8.5 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer2 PF00111.27 CBY13006.1 - 0.042 13.8 1.4 0.042 13.8 1.4 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 CBY13006.1 - 0.12 12.6 5.7 0.38 10.9 0.1 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain UQ_con PF00179.26 CBY13007.1 - 2.9e-40 137.1 0.1 3.6e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CBY13007.1 - 0.064 13.1 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 CBY13007.1 - 0.1 12.9 0.2 0.15 12.4 0.2 1.4 1 1 0 1 1 1 0 RWD domain Actin PF00022.19 CBY13008.1 - 1.3e-112 376.4 0.0 1.1e-111 373.4 0.0 1.9 1 1 0 1 1 1 1 Actin Fra10Ac1 PF09725.9 CBY13009.1 - 0.088 12.9 1.0 0.097 12.8 1.0 1.0 1 0 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 SpoU_methylase PF00588.19 CBY13012.1 - 4.8e-26 91.6 0.1 9.9e-26 90.6 0.1 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family Atx10homo_assoc PF09759.9 CBY13012.1 - 0.74 9.9 4.4 6.7 6.8 0.0 3.7 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain CAP PF00188.26 CBY13014.1 - 6.4e-08 33.5 0.6 1.1e-07 32.7 0.6 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CRF-BP PF05428.11 CBY13014.1 - 0.084 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Sushi PF00084.20 CBY13014.1 - 4.7 7.9 8.3 3.2 8.4 3.0 2.7 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Ion_trans PF00520.31 CBY13016.1 - 6.6e-09 35.4 19.4 1.8e-08 33.9 19.4 1.7 1 1 0 1 1 1 1 Ion transport protein CUB PF00431.20 CBY13017.1 - 0.00011 22.6 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 CUB domain MGC-24 PF05283.11 CBY13017.1 - 8.5 6.8 9.2 0.32 11.4 2.9 1.8 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin F-box-like PF12937.7 CBY13019.1 - 3.8e-05 23.5 0.1 6.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY13019.1 - 0.00049 19.9 0.5 0.0013 18.5 0.3 1.7 1 1 0 1 1 1 1 F-box domain Acetyltransf_1 PF00583.25 CBY13020.1 - 5.4e-14 52.4 0.0 7.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY13020.1 - 5.4e-09 36.4 0.1 9.2e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY13020.1 - 1.5e-05 24.9 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY13020.1 - 0.00027 20.8 0.0 0.00047 20.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CBY13020.1 - 0.0024 17.9 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 CBY13020.1 - 0.022 15.4 0.0 0.038 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 CBY13020.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Lon_C PF05362.13 CBY13021.1 - 4.3e-64 215.8 0.2 1.1e-63 214.5 0.2 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CBY13021.1 - 1.4e-22 80.5 0.0 1.2e-21 77.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBY13021.1 - 1.5e-07 31.3 0.0 3.7e-06 26.8 0.0 2.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CBY13021.1 - 1.4e-06 28.5 0.1 1.3e-05 25.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 CBY13021.1 - 6e-06 25.4 0.1 1.4e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_5 PF07728.14 CBY13021.1 - 6.6e-06 26.2 0.0 1.6e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY13021.1 - 1.1e-05 25.9 0.1 6.5e-05 23.4 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBY13021.1 - 6.7e-05 23.2 1.7 0.0059 16.9 0.1 3.9 2 2 1 3 3 3 1 AAA domain AAA_11 PF13086.6 CBY13021.1 - 0.00025 20.9 1.8 0.056 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ChlI PF13541.6 CBY13021.1 - 0.0014 18.5 0.6 0.0053 16.6 0.8 1.9 1 1 1 2 2 2 1 Subunit ChlI of Mg-chelatase NB-ARC PF00931.22 CBY13021.1 - 0.0021 17.3 0.5 0.027 13.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TIP49 PF06068.13 CBY13021.1 - 0.0031 16.8 0.0 0.0031 16.8 0.0 3.1 4 0 0 4 4 4 1 TIP49 P-loop domain RNA_helicase PF00910.22 CBY13021.1 - 0.0062 16.9 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 CBY13021.1 - 0.0068 16.6 0.3 0.019 15.1 0.1 1.9 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 CBY13021.1 - 0.0081 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 CBY13021.1 - 0.0086 16.1 0.0 0.025 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY13021.1 - 0.0092 16.5 0.5 0.036 14.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.6 CBY13021.1 - 0.011 16.2 2.4 0.21 12.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CBY13021.1 - 0.014 15.1 2.0 0.15 11.7 0.0 2.7 2 1 0 2 2 2 0 Cytidylate kinase Torsin PF06309.11 CBY13021.1 - 0.016 15.3 0.0 0.059 13.5 0.0 1.9 1 0 0 1 1 1 0 Torsin IstB_IS21 PF01695.17 CBY13021.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 CBY13021.1 - 0.025 14.6 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CBY13021.1 - 0.028 14.4 0.1 0.28 11.1 0.0 2.4 2 1 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 CBY13021.1 - 0.029 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CBY13021.1 - 0.031 14.2 0.2 2.2 8.1 0.0 3.1 1 1 1 2 2 2 0 NTPase Mg_chelatase PF01078.21 CBY13021.1 - 0.034 13.5 0.0 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_6 PF12774.7 CBY13021.1 - 0.045 12.7 0.6 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Parvo_NS1 PF01057.17 CBY13021.1 - 0.049 12.7 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 CBY13021.1 - 0.063 13.1 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CBY13021.1 - 0.085 13.2 0.0 0.61 10.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CBY13021.1 - 0.086 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBY13021.1 - 0.76 10.3 4.5 0.71 10.4 0.1 2.8 2 1 0 3 3 2 0 ABC transporter AAA_17 PF13207.6 CBY13021.1 - 3.1 8.2 6.7 1 9.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain UQ_con PF00179.26 CBY13022.1 - 3.7e-45 153.0 0.1 4.9e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY13022.1 - 0.00075 19.2 0.0 0.0021 17.8 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBY13022.1 - 0.011 16.0 0.1 0.019 15.2 0.1 1.6 1 0 0 1 1 1 0 RWD domain F-box PF00646.33 CBY13025.1 - 3.1e-06 26.9 1.2 4.5e-05 23.2 0.2 2.3 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 CBY13025.1 - 1.4e-05 24.8 0.1 2.6e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 F-box-like CUB PF00431.20 CBY13026.1 - 3.3e-08 33.8 0.2 6.2e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 CUB domain CUB PF00431.20 CBY13027.1 - 0.1 13.0 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 CUB domain Tubulin PF00091.25 CBY13029.1 - 5.5e-67 225.8 0.0 7.2e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY13029.1 - 2.2e-51 173.3 0.0 3.5e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY13029.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Nkap_C PF06047.11 CBY13030.1 - 1.8e-37 127.6 5.8 1.8e-37 127.6 5.8 2.9 2 1 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain RNA_polI_A34 PF08208.11 CBY13030.1 - 1.2 9.1 30.5 0.56 10.3 27.2 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.9 CBY13030.1 - 2 8.0 38.7 0.25 10.9 31.5 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein THOC2_N PF16134.5 CBY13030.1 - 4.2 5.9 15.2 7 5.1 15.2 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus LicD PF04991.13 CBY13030.1 - 8.6 6.4 17.2 2.2 8.3 11.3 2.1 2 0 0 2 2 2 0 LicD family DUF913 PF06025.12 CBY13030.1 - 9.3 5.1 10.1 15 4.4 10.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Dynein_light PF01221.18 CBY13031.1 - 1.2e-20 73.5 0.1 1.7e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 TPR_19 PF14559.6 CBY13032.1 - 1.3e-17 64.0 3.9 0.00027 21.4 0.9 5.8 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY13032.1 - 2.4e-13 49.1 21.1 0.14 12.4 0.1 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY13032.1 - 3.6e-12 46.3 17.9 0.012 15.9 0.2 6.2 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CBY13032.1 - 7e-09 36.2 0.6 0.81 10.4 0.0 5.9 6 1 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY13032.1 - 7e-08 32.7 1.3 2.4 9.2 0.0 6.9 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY13032.1 - 6.8e-06 26.1 6.7 0.22 12.0 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY13032.1 - 9.3e-06 25.8 9.2 11 6.4 0.0 6.8 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY13032.1 - 9.7e-06 25.3 5.2 0.31 11.2 0.0 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY13032.1 - 3.8e-05 24.0 17.1 0.4 11.4 0.3 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat PPR PF01535.20 CBY13032.1 - 4e-05 23.6 1.2 10 6.6 0.0 5.2 5 0 0 5 5 4 0 PPR repeat HrpB1_HrpK PF09613.10 CBY13032.1 - 0.00013 21.6 0.1 1.8 8.2 0.0 4.7 2 2 4 6 6 6 1 Bacterial type III secretion protein (HrpB1_HrpK) PPR_2 PF13041.6 CBY13032.1 - 0.0014 18.7 0.9 16 5.8 0.0 4.8 4 1 1 5 5 4 0 PPR repeat family RPN7 PF10602.9 CBY13032.1 - 0.0025 17.5 0.1 0.078 12.7 0.0 2.7 2 1 0 2 2 2 1 26S proteasome subunit RPN7 Coatomer_E PF04733.14 CBY13032.1 - 0.0026 17.2 0.2 0.46 9.8 0.0 3.2 2 1 0 3 3 3 1 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 CBY13032.1 - 0.0033 17.4 5.8 0.32 11.1 0.0 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CBY13032.1 - 0.005 16.7 13.2 0.45 10.5 0.1 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY13032.1 - 0.0081 15.8 0.6 0.6 9.8 0.0 3.7 4 0 0 4 4 4 1 TPR repeat TPR_4 PF07721.14 CBY13032.1 - 0.0087 16.6 0.0 8.9 7.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY13032.1 - 0.011 15.5 16.4 1 9.3 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY13032.1 - 0.014 15.5 0.0 2.4 8.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY13032.1 - 0.061 13.6 10.4 13 6.3 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-MIZ PF02891.20 CBY13033.1 - 0.00017 21.2 0.2 0.00038 20.1 0.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Ank_3 PF13606.6 CBY13033.1 - 0.012 16.1 0.0 0.044 14.3 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat DUF3767 PF12597.8 CBY13033.1 - 0.13 12.0 1.6 0.37 10.6 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) TEX13 PF15186.6 CBY13033.1 - 0.56 9.9 15.6 0.037 13.7 7.7 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family Lebercilin PF15619.6 CBY13033.1 - 0.58 9.8 22.2 0.22 11.2 19.0 1.8 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4349 PF14257.6 CBY13033.1 - 1.4 8.3 6.1 1.7 8.1 4.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF4578 PF15147.6 CBY13033.1 - 1.5 9.7 7.5 3.4 8.6 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) zf-Nse PF11789.8 CBY13033.1 - 1.7 8.5 5.0 0.58 10.0 0.6 2.6 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit DUF4407 PF14362.6 CBY13033.1 - 2.2 7.5 10.0 3.6 6.9 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EMC3_TMCO1 PF01956.16 CBY13033.1 - 9.1 6.0 9.6 20 4.9 9.6 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MRP-S23 PF10484.9 CBY13034.1 - 8.6e-15 55.1 0.4 1.4e-14 54.5 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 Pkinase PF00069.25 CBY13035.1 - 8.3e-74 248.3 0.0 1.3e-73 247.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13035.1 - 2.8e-39 134.9 0.0 5.4e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY13035.1 - 1.9e-06 28.0 0.1 0.0014 18.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CBY13035.1 - 3.4e-05 23.3 0.4 6.4e-05 22.4 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY13035.1 - 5.4e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY13035.1 - 0.0018 17.3 0.3 0.0041 16.1 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CBY13035.1 - 0.0039 16.8 0.1 0.013 15.1 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase DHODB_Fe-S_bind PF10418.9 CBY13036.1 - 0.016 15.0 6.7 0.95 9.3 0.2 4.0 4 0 0 4 4 4 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B SET PF00856.28 CBY13037.1 - 5e-09 36.8 0.0 5.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 SET domain PI-PLC-X PF00388.19 CBY13038.1 - 1.5e-32 112.2 0.1 2.8e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY13038.1 - 1.4e-27 96.3 0.0 3.9e-27 94.9 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CBY13038.1 - 6.9e-13 48.8 0.0 2.1e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 CBY13038.1 - 7.1e-13 48.9 0.0 1.7e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_12 PF16457.5 CBY13038.1 - 4.2e-12 46.8 0.0 1.1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CBY13038.1 - 0.0023 18.4 0.2 0.0064 17.0 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_14 PF17787.1 CBY13038.1 - 0.0038 17.1 0.0 0.0095 15.8 0.0 1.7 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 CBY13038.1 - 0.0039 17.6 0.1 0.021 15.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair Mcp5_PH PF12814.7 CBY13038.1 - 0.0086 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_1 PF00036.32 CBY13038.1 - 0.034 13.7 0.1 0.079 12.5 0.1 1.7 1 0 0 1 1 1 0 EF hand IQ PF00612.27 CBY13039.1 - 0.24 11.3 8.7 2.7 8.0 0.1 3.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif KIP1 PF07765.12 CBY13040.1 - 0.025 14.7 0.1 0.075 13.2 0.1 1.8 1 0 0 1 1 1 0 KIP1-like protein 2OG-FeII_Oxy_3 PF13640.6 CBY13041.1 - 1.4e-07 32.3 0.0 2.8e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Anp1 PF03452.14 CBY13041.1 - 0.03 13.7 0.1 9.5 5.5 0.0 3.0 2 1 1 3 3 3 0 Anp1 Tetraspanin PF00335.20 CBY13042.1 - 1.4e-09 38.1 15.9 3.1e-08 33.6 15.9 2.2 1 1 0 1 1 1 1 Tetraspanin family Herpes_UL1 PF05259.11 CBY13042.1 - 0.061 13.4 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus glycoprotein L Cation_ATPase_C PF00689.21 CBY13042.1 - 0.41 10.3 6.5 0.069 12.9 2.4 1.6 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF2207 PF09972.9 CBY13042.1 - 3.4 6.3 8.5 1.6 7.4 5.2 1.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) TraG_N PF07916.11 CBY13042.1 - 9.2 5.0 6.4 6.5 5.5 3.5 2.0 1 1 1 2 2 2 0 TraG-like protein, N-terminal region Ras PF00071.22 CBY13043.1 - 1.6e-53 180.6 0.0 1.8e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY13043.1 - 3.8e-26 91.7 0.0 5.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY13043.1 - 1.1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBY13043.1 - 0.00027 20.4 0.0 0.00036 20.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY13043.1 - 0.00045 19.8 0.1 0.00089 18.8 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY13043.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY13043.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ldh_1_N PF00056.23 CBY13043.1 - 0.067 13.3 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Pdase_M17_N2 PF18295.1 CBY13043.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 Lipase_GDSL_3 PF14606.6 CBY13043.1 - 0.18 11.9 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TniB PF05621.11 CBY13043.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Peptidase_M14 PF00246.24 CBY13044.1 - 6.8e-65 219.7 0.0 8.9e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_M14 PF00246.24 CBY13045.1 - 3.6e-63 214.1 0.1 5e-63 213.6 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Thioredoxin_7 PF13899.6 CBY13046.1 - 3.8e-05 23.8 0.1 5.5e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Lectin_C PF00059.21 CBY13047.1 - 1.6e-18 67.4 0.7 6.5e-18 65.4 0.7 2.1 1 0 0 1 1 1 1 Lectin C-type domain DUF349 PF03993.12 CBY13047.1 - 3 8.2 11.0 0.51 10.7 5.9 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Copine PF07002.16 CBY13048.1 - 6.3e-79 264.4 0.1 8.8e-79 264.0 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 CBY13048.1 - 1.7e-09 37.9 0.0 1.1e-08 35.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain vWA-TerF-like PF10138.9 CBY13048.1 - 8.6e-05 22.7 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus PDZ PF00595.24 CBY13049.1 - 1.3e-08 35.0 0.3 3.4e-08 33.7 0.3 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY13049.1 - 7.2e-07 29.0 0.1 1.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY13049.1 - 0.00078 19.7 0.2 0.0015 18.8 0.2 1.5 1 0 0 1 1 1 1 PDZ domain TraI_2B PF18340.1 CBY13049.1 - 0.0016 18.4 0.0 0.0048 16.9 0.0 1.8 1 0 0 1 1 1 1 DNA relaxase TraI 2B/2B-like domain Pns11_12 PF17464.2 CBY13049.1 - 0.012 15.3 26.4 0.054 13.2 13.7 2.3 2 0 0 2 2 2 0 Non-structural protein 11 and 12 RSRP PF17069.5 CBY13049.1 - 2.1 7.9 45.9 2.1 7.9 18.4 2.2 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 PNISR PF15996.5 CBY13049.1 - 4.3 7.6 23.9 0.86 9.8 13.9 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Transformer PF06495.11 CBY13049.1 - 5.6 7.0 31.8 1.6 8.8 13.3 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein PRP38_assoc PF12871.7 CBY13049.1 - 6.8 7.4 47.2 2.2 8.9 22.1 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Afi1 PF07792.12 CBY13049.1 - 7.8 7.0 15.5 1.6 9.3 0.5 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PDZ PF00595.24 CBY13050.1 - 4.2e-10 39.9 0.1 6.6e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY13050.1 - 0.00039 20.2 0.0 0.0009 19.0 0.0 1.6 2 0 0 2 2 2 1 PDZ domain YabA PF06156.13 CBY13051.1 - 0.0035 17.9 2.7 0.0035 17.9 2.7 2.2 2 1 0 2 2 2 1 Initiation control protein YabA HTH_12 PF08461.10 CBY13051.1 - 0.015 15.2 0.5 0.037 14.0 0.5 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain KASH_CCD PF14662.6 CBY13051.1 - 0.017 15.0 6.5 0.017 15.0 6.5 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ABC_tran_CTD PF16326.5 CBY13051.1 - 0.13 12.6 6.5 4.5 7.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain CHDCT2 PF08074.11 CBY13051.1 - 0.15 12.3 4.5 1.9 8.6 0.2 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain AAA_11 PF13086.6 CBY13051.1 - 0.58 9.9 8.0 0.84 9.4 8.0 1.3 1 0 0 1 1 1 0 AAA domain IFP_35_N PF07334.13 CBY13051.1 - 1.7 8.8 8.1 0.67 10.1 5.1 1.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF2681 PF10883.8 CBY13051.1 - 9.7 6.7 9.7 24 5.4 9.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3781 PF12636.7 CBY13053.1 - 0.048 13.5 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Man-6-P_recep PF02157.15 CBY13054.1 - 1e-09 37.8 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 CBY13054.1 - 1.8e-05 24.7 0.1 1.9e-05 24.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 RCR PF12273.8 CBY13054.1 - 0.085 13.5 0.6 0.11 13.1 0.6 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF5542 PF17696.1 CBY13054.1 - 0.13 12.4 0.6 0.94 9.6 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5542) TMEM132D_C PF15706.5 CBY13054.1 - 0.17 11.7 0.1 0.42 10.4 0.1 1.6 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term eIF_4EBP PF05456.11 CBY13056.1 - 7.7e-06 25.8 0.3 2.1e-05 24.4 0.0 1.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RE_BstXI PF09552.10 CBY13056.1 - 0.07 12.3 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 BstXI restriction endonuclease WD40 PF00400.32 CBY13057.1 - 5.9e-20 71.2 10.6 0.00051 20.8 0.3 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY13057.1 - 8.9e-08 32.3 3.7 0.24 11.7 0.0 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CBY13057.1 - 0.0069 16.4 0.4 0.13 12.3 0.1 3.0 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region zf-H2C2_2 PF13465.6 CBY13058.1 - 7.7e-21 73.5 11.9 8.1e-08 32.4 0.1 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY13058.1 - 3.5e-19 68.1 16.1 7.6e-07 29.2 3.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY13058.1 - 1.8e-14 53.2 12.4 0.00024 21.6 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 CBY13058.1 - 7.1e-12 45.4 2.5 3.8e-08 33.5 1.1 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CBY13058.1 - 2.6e-10 40.3 1.1 0.002 18.4 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY13058.1 - 1.2e-08 34.7 6.5 0.012 15.6 0.5 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.15 CBY13058.1 - 1.4e-07 31.4 10.0 0.018 15.0 0.7 3.6 2 1 1 3 3 3 3 BED zinc finger GAGA PF09237.11 CBY13058.1 - 6.7e-07 29.0 7.5 0.0082 15.9 0.4 3.6 1 1 2 3 3 3 2 GAGA factor zf-met PF12874.7 CBY13058.1 - 9e-05 22.7 5.5 1.6 9.2 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CBY13058.1 - 0.00054 19.7 24.1 0.012 15.4 0.3 4.5 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CBY13058.1 - 0.00056 19.6 11.5 0.1 12.4 0.2 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CBY13058.1 - 0.0067 16.7 2.9 4.7 7.6 0.1 3.4 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 CBY13058.1 - 0.011 15.3 0.7 18 5.0 0.0 3.2 1 1 2 3 3 3 0 MYST family zinc finger domain zf_UBZ PF18439.1 CBY13058.1 - 0.012 15.2 2.4 1.8 8.2 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF4611 PF15387.6 CBY13058.1 - 0.029 14.6 0.6 0.065 13.5 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zinc_ribbon_15 PF17032.5 CBY13058.1 - 0.057 14.2 1.3 2.7 8.8 0.2 2.5 1 1 1 2 2 2 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 CBY13058.1 - 0.09 12.9 7.1 7.3 6.7 0.4 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-C2H2_8 PF15909.5 CBY13058.1 - 0.11 12.8 4.6 2.4 8.5 2.6 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon DUF629 PF04780.12 CBY13058.1 - 0.25 9.9 1.5 4 5.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.6 CBY13058.1 - 0.25 11.3 13.4 4.4 7.3 1.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf_ZIC PF18366.1 CBY13058.1 - 0.32 11.1 2.0 32 4.7 0.1 3.8 2 1 2 4 4 4 0 Zic proteins zinc finger domain UBZ_FAAP20 PF15750.5 CBY13058.1 - 0.37 10.8 2.8 21 5.1 0.0 2.8 3 0 0 3 3 2 0 Ubiquitin-binding zinc-finger zf-C2H2_3rep PF18868.1 CBY13058.1 - 0.39 11.4 11.7 1.3 9.7 0.6 3.5 2 1 2 4 4 3 0 Zinc finger C2H2-type, 3 repeats Elf1 PF05129.13 CBY13058.1 - 0.41 10.7 3.8 17 5.5 0.1 2.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 CBY13058.1 - 0.63 10.3 12.2 1.4 9.2 0.5 3.5 4 0 0 4 4 3 0 AN1-like Zinc finger zf-C2HE PF16278.5 CBY13058.1 - 0.81 10.2 6.7 6.1 7.4 0.5 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF1644 PF07800.12 CBY13058.1 - 2.7 8.0 12.7 6.5 6.8 8.2 3.0 2 1 0 2 2 1 0 Protein of unknown function (DUF1644) Sugar_tr PF00083.24 CBY13059.1 - 1.8e-25 89.8 24.4 5.6e-25 88.1 24.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY13059.1 - 8.5e-24 84.1 61.3 4.6e-18 65.3 32.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Scramblase PF03803.15 CBY13060.1 - 0.055 12.8 0.1 0.083 12.2 0.1 1.2 1 0 0 1 1 1 0 Scramblase Abi_HHR PF07815.14 CBY13060.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Abl-interactor HHR RLL PF10036.9 CBY13062.1 - 5.1e-62 210.0 7.3 9.3e-62 209.2 7.3 1.4 1 1 0 1 1 1 1 RNA transcription, translation and transport factor protein CIA30 PF08547.12 CBY13063.1 - 1.7e-38 132.1 0.2 3e-38 131.4 0.2 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) LON_substr_bdg PF02190.16 CBY13064.1 - 1e-22 81.1 0.0 1.3e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 CBY13064.1 - 1.9e-10 40.9 0.5 3.8e-10 39.9 0.1 1.6 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Homeodomain PF00046.29 CBY13068.1 - 6.2e-20 70.8 7.1 9.8e-20 70.2 7.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY13068.1 - 0.0028 17.5 0.2 0.0064 16.4 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CBY13068.1 - 0.0077 15.7 0.4 0.015 14.8 0.4 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Yip1 PF04893.17 CBY13070.1 - 1.5e-10 41.1 11.5 2e-10 40.6 11.5 1.1 1 0 0 1 1 1 1 Yip1 domain DUF3487 PF11990.8 CBY13070.1 - 0.11 12.4 3.1 0.92 9.4 2.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) IMPDH PF00478.25 CBY13071.1 - 3.6e-78 263.0 0.7 4.8e-78 262.6 0.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Aldolase PF01081.19 CBY13071.1 - 0.035 13.5 0.7 0.31 10.4 0.0 2.1 1 1 0 2 2 2 0 KDPG and KHG aldolase FMN_dh PF01070.18 CBY13071.1 - 0.036 13.1 4.4 0.06 12.4 4.1 1.3 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Arginosuc_synth PF00764.19 CBY13071.1 - 0.067 12.5 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase CH_2 PF06294.11 CBY13073.1 - 6.7e-10 39.0 0.0 2.4e-09 37.2 0.0 2.1 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 CBY13073.1 - 0.0014 18.7 0.1 0.0046 17.1 0.1 1.8 1 0 0 1 1 1 1 Adenylate kinase Coilin_N PF15862.5 CBY13073.1 - 0.0019 18.0 0.1 0.0019 18.0 0.1 4.0 3 1 0 3 3 3 1 Coilin N-terminus TUDOR PF00567.24 CBY13073.1 - 0.04 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 Tudor domain EzrA PF06160.12 CBY13074.1 - 0.044 12.0 15.8 0.069 11.3 15.8 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 CBY13074.1 - 0.057 13.5 7.2 0.18 11.9 3.4 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RseC_MucC PF04246.12 CBY13074.1 - 0.066 13.2 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC COG2 PF06148.11 CBY13074.1 - 0.077 13.1 10.0 1.3 9.1 0.5 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF812 PF05667.11 CBY13074.1 - 0.098 11.5 18.2 0.13 11.1 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF948 PF06103.11 CBY13074.1 - 0.26 11.6 3.8 0.2 11.9 0.6 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 CBY13074.1 - 0.46 11.1 10.4 0.86 10.2 7.0 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal YabA PF06156.13 CBY13074.1 - 0.87 10.3 15.5 3.9 8.2 3.2 2.5 2 0 0 2 2 2 0 Initiation control protein YabA CCDC-167 PF15188.6 CBY13074.1 - 0.94 9.9 13.4 0.24 11.7 2.4 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Seryl_tRNA_N PF02403.22 CBY13074.1 - 1.5 9.1 17.7 0.16 12.2 4.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 CBY13074.1 - 1.6 7.9 13.3 0.62 9.3 8.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein Cluap1 PF10234.9 CBY13074.1 - 2 7.7 16.7 0.8 9.1 14.1 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 Spc7 PF08317.11 CBY13074.1 - 2.3 7.0 21.5 0.6 8.9 15.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CBY13074.1 - 3.5 7.7 7.5 1.1 9.3 2.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 CBY13074.1 - 6.4 6.9 24.2 1.5 8.9 1.8 2.8 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain LMBR1 PF04791.16 CBY13074.1 - 8.5 5.2 9.1 9.8 5.0 9.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4572 PF15139.6 CBY13075.1 - 8.9e-29 100.8 4.9 1.3e-28 100.2 4.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) G-alpha PF00503.20 CBY13077.1 - 2.3e-88 296.8 6.8 2.8e-88 296.5 6.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY13077.1 - 1.6e-13 50.5 0.2 4.8e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 CBY13078.1 - 2.3e-11 43.5 0.4 2.5e-11 43.3 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 CBY13078.1 - 0.0042 16.5 0.0 0.0044 16.4 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family Arf PF00025.21 CBY13078.1 - 0.0042 16.5 0.1 0.0048 16.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_29 PF13555.6 CBY13078.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CBY13078.1 - 0.015 14.7 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein DUF2951 PF11166.8 CBY13078.1 - 0.017 15.3 0.4 0.019 15.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DAP3 PF10236.9 CBY13078.1 - 0.027 13.6 0.3 0.03 13.5 0.3 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNaseH_pPIWI_RE PF13032.6 CBY13080.1 - 0.064 13.2 0.0 0.071 13.0 0.0 1.0 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE Glyco_trans_1_2 PF13524.6 CBY13080.1 - 0.12 12.7 0.7 0.16 12.4 0.6 1.3 1 1 0 1 1 1 0 Glycosyl transferases group 1 Trypsin PF00089.26 CBY13081.1 - 1.5e-38 132.8 0.2 9.1e-38 130.3 0.0 1.9 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY13081.1 - 1.7e-09 38.8 0.0 3.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Sushi PF00084.20 CBY13081.1 - 5.3e-06 26.9 23.3 0.00064 20.3 5.9 3.6 4 0 0 4 4 4 2 Sushi repeat (SCR repeat) cEGF PF12662.7 CBY13081.1 - 1.5 8.9 15.8 0.05 13.6 2.4 3.4 2 1 1 3 3 3 0 Complement Clr-like EGF-like Ephrin_rec_like PF07699.13 CBY13082.1 - 1.9e-07 30.7 73.8 0.0019 18.0 4.7 9.4 3 3 6 9 9 9 6 Putative ephrin-receptor like COesterase PF00135.28 CBY13083.1 - 2.9e-88 297.0 0.0 4.3e-88 296.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY13083.1 - 1.9e-10 41.0 0.3 2.6e-09 37.3 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CBY13083.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 CBY13083.1 - 0.00059 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family B277 PF17623.2 CBY13083.1 - 0.016 14.3 6.6 0.026 13.6 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function Mucin PF01456.17 CBY13083.1 - 0.93 9.5 21.7 1.7 8.7 21.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 CBY13083.1 - 2.8 7.9 18.4 7 6.6 18.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.11 CBY13083.1 - 4.7 7.1 9.4 7.5 6.5 9.4 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF4392 PF14336.6 CBY13084.1 - 3.4e-73 246.7 0.0 5.3e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.12 CBY13084.1 - 1e-54 184.4 0.0 3.3e-54 182.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1445) Kri1 PF05178.12 CBY13086.1 - 0.24 12.0 4.8 0.4 11.2 4.8 1.3 1 0 0 1 1 1 0 KRI1-like family DASH_Dam1 PF08653.10 CBY13087.1 - 0.014 15.2 0.7 0.55 10.1 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 STAT_alpha PF01017.20 CBY13087.1 - 0.028 14.3 0.9 0.039 13.9 0.9 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain CLZ PF16526.5 CBY13087.1 - 0.12 12.8 1.6 3.3 8.1 0.2 2.3 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Kelch_5 PF13854.6 CBY13089.1 - 0.0068 16.4 0.1 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 CBY13089.1 - 0.059 13.7 0.1 0.27 11.6 0.0 2.2 2 0 0 2 2 2 0 Kelch motif RT_RNaseH PF17917.1 CBY13091.1 - 4.1e-26 91.3 0.0 9.1e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY13091.1 - 5.9e-24 84.0 0.0 1.6e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY13091.1 - 4.2e-17 62.4 0.0 1.3e-16 60.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY13091.1 - 1e-12 48.0 0.1 2.3e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain MLVIN_C PF18697.1 CBY13091.1 - 0.023 14.8 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain rve_3 PF13683.6 CBY13091.1 - 0.04 13.7 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain zf-C3HC4_3 PF13920.6 CBY13092.1 - 0.00012 21.9 14.1 0.00012 21.9 14.1 2.9 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY13092.1 - 0.00014 21.9 11.8 0.00014 21.9 11.8 2.3 1 1 1 2 2 2 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 CBY13092.1 - 0.00019 21.7 16.6 0.00019 21.7 16.6 3.1 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY13092.1 - 0.00023 20.9 16.2 0.00023 20.9 16.2 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY13092.1 - 0.00037 20.3 16.9 0.00037 20.3 16.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF3573 PF12097.8 CBY13092.1 - 0.01 14.7 4.3 0.011 14.6 3.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) zf-RING_6 PF14835.6 CBY13092.1 - 0.027 14.3 7.3 0.066 13.1 7.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RAG1 PF10426.9 CBY13092.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.6 2 1 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain OmpH PF03938.14 CBY13092.1 - 0.4 11.0 13.7 0.64 10.4 13.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GBP_C PF02841.14 CBY13092.1 - 0.43 9.9 20.8 0.66 9.3 20.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain PspB PF06667.12 CBY13092.1 - 0.47 10.5 2.3 0.89 9.7 1.2 2.0 1 1 1 2 2 2 0 Phage shock protein B zf-C3HC4_4 PF15227.6 CBY13092.1 - 0.61 10.3 24.2 0.73 10.0 16.6 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING CFAP91 PF14738.6 CBY13092.1 - 0.65 10.0 16.2 3.8 7.6 0.0 2.5 2 1 0 2 2 2 0 Cilia- and flagella-associated protein 91 Jnk-SapK_ap_N PF09744.9 CBY13092.1 - 1.6 8.9 19.5 3.3 7.9 19.5 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 CBY13092.1 - 2.8 7.2 6.9 4 6.7 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Striatin PF08232.12 CBY13092.1 - 7.1 7.2 17.0 18 5.9 16.7 1.8 1 1 0 1 1 1 0 Striatin family Methyltransf_22 PF13383.6 CBY13093.1 - 7.6e-10 38.8 0.8 1.6e-09 37.7 0.8 1.7 1 1 0 1 1 1 1 Methyltransferase domain Thioredoxin PF00085.20 CBY13094.1 - 2.1e-33 114.4 1.0 8.6e-16 57.8 0.5 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 CBY13094.1 - 2e-09 37.9 0.7 1.4e-05 25.5 0.5 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY13094.1 - 0.0011 19.1 0.2 0.029 14.6 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like HyaE PF07449.11 CBY13094.1 - 0.0014 18.5 0.1 13 5.8 0.0 3.8 4 0 0 4 4 4 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 CBY13094.1 - 0.0058 16.5 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 CBY13094.1 - 0.013 14.8 7.4 0.027 13.8 2.0 2.8 1 1 2 3 3 3 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBY13094.1 - 0.013 15.8 0.1 0.087 13.2 0.2 2.3 2 1 0 2 2 2 0 Thioredoxin-like DsrD PF08679.11 CBY13094.1 - 0.25 11.7 2.0 0.81 10.0 0.8 2.5 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) Thioredoxin PF00085.20 CBY13095.1 - 3.5e-08 33.3 0.2 7.2e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Pox_MCEL PF03291.16 CBY13095.1 - 0.043 12.9 0.4 0.14 11.3 0.1 1.9 2 1 0 2 2 2 0 mRNA capping enzyme Trypsin PF00089.26 CBY13096.1 - 9.2e-49 166.2 5.8 4.5e-47 160.7 1.6 2.7 2 1 0 2 2 2 1 Trypsin DUF1986 PF09342.11 CBY13096.1 - 6.7e-05 23.3 0.0 0.00016 22.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF3439 PF11921.8 CBY13096.1 - 0.0066 16.4 1.7 0.014 15.3 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Trypsin_2 PF13365.6 CBY13096.1 - 0.013 16.4 0.0 0.031 15.2 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain Presenilin PF01080.17 CBY13097.1 - 1.1 8.0 5.6 1.2 7.8 5.6 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CBY13097.1 - 1.1 9.3 3.5 1.2 9.1 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_11 PF13086.6 CBY13097.1 - 5.3 6.7 10.6 6.9 6.4 10.6 1.2 1 0 0 1 1 1 0 AAA domain Serpin PF00079.20 CBY13098.1 - 2.3e-58 198.3 0.1 3e-58 197.9 0.1 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Nbas_N PF15492.6 CBY13098.1 - 0.027 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal FOG_N PF15888.5 CBY13099.1 - 0.056 13.8 0.2 0.086 13.2 0.2 1.3 1 0 0 1 1 1 0 Folded gastrulation N-terminus LRR_4 PF12799.7 CBY13100.1 - 0.096 13.1 5.3 5.5 7.6 0.3 3.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Kelch_2 PF07646.15 CBY13101.1 - 3.5e-05 23.6 1.3 0.71 9.9 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY13101.1 - 0.00062 19.7 0.8 0.067 13.2 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY13101.1 - 0.018 15.3 2.4 0.96 9.8 0.0 3.5 4 0 0 4 4 4 0 Kelch motif EF-hand_1 PF00036.32 CBY13102.1 - 3.5e-24 82.5 9.7 4.6e-07 28.9 0.7 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY13102.1 - 4.5e-24 84.7 3.9 1.2e-15 57.7 0.4 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY13102.1 - 8.9e-23 78.2 4.0 6.5e-06 25.7 0.2 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CBY13102.1 - 1.4e-19 68.7 9.6 2.8e-06 26.6 0.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY13102.1 - 2.2e-19 69.0 7.1 2.1e-09 37.1 0.6 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CBY13102.1 - 1.4e-06 28.2 3.1 0.024 14.6 0.0 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY13102.1 - 3.7e-06 27.2 2.7 0.0032 17.8 0.3 3.1 1 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Homez PF11569.8 CBY13102.1 - 0.0085 15.5 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Caleosin PF05042.13 CBY13102.1 - 0.014 15.4 3.1 1.5 8.8 0.1 3.2 1 1 1 3 3 3 0 Caleosin related protein PMBR PF09373.10 CBY13102.1 - 0.065 13.4 0.1 54 4.2 0.0 4.0 5 0 0 5 5 5 0 Pseudomurein-binding repeat EF-hand_14 PF17959.1 CBY13102.1 - 0.18 12.2 3.2 2.3 8.6 0.8 2.9 2 1 0 2 2 2 0 EF-hand domain zf-C2HC PF01530.18 CBY13103.1 - 1e-24 86.4 32.3 8.3e-13 48.3 8.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2HC type IBR PF01485.21 CBY13103.1 - 0.039 14.2 4.0 0.83 9.9 0.2 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain NUC PF18510.1 CBY13103.1 - 0.088 13.3 0.5 0.17 12.3 0.5 1.4 1 0 0 1 1 1 0 Nuclease domain Peptidase_S64 PF08192.11 CBY13103.1 - 5 5.5 10.9 6.2 5.2 10.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 RT_RNaseH_2 PF17919.1 CBY13104.1 - 3.1e-10 40.0 0.0 6.7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY13104.1 - 5.1e-07 29.4 0.1 9.4e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CBY13104.1 - 0.00011 22.4 0.0 0.00034 20.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DNA_pol_viral_C PF00336.18 CBY13104.1 - 0.017 14.6 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Vezatin PF12632.7 CBY13104.1 - 0.069 12.5 0.1 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes Lactamase_B_6 PF16661.5 CBY13104.1 - 0.12 11.8 0.1 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain EGF_CA PF07645.15 CBY13108.1 - 2e-07 31.1 9.1 2e-07 31.1 9.1 3.8 2 1 2 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.7 CBY13108.1 - 1.7e-05 24.6 2.9 1.7e-05 24.6 2.9 4.0 3 0 0 3 3 3 1 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY13108.1 - 0.016 15.4 6.2 0.016 15.4 6.2 3.2 3 0 0 3 3 3 0 EGF domain EGF PF00008.27 CBY13108.1 - 0.6 10.5 10.5 5.2 7.5 0.3 3.5 3 1 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.6 CBY13108.1 - 0.99 9.7 16.4 4.2 7.7 0.2 3.7 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY13108.1 - 2.3 9.0 14.6 0.41 11.4 1.1 4.1 4 0 0 4 4 4 0 Human growth factor-like EGF Mito_carr PF00153.27 CBY13109.1 - 8.4e-62 205.1 1.8 5.7e-21 74.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PDEase_I PF00233.19 CBY13109.1 - 7.5e-37 127.3 7.5 1.2e-36 126.7 7.5 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MFS_2 PF13347.6 CBY13110.1 - 5.6e-18 64.7 25.5 9.6e-18 63.9 25.3 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CBY13110.1 - 6.2e-13 48.4 30.5 6.2e-13 48.4 30.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3624 PF12292.8 CBY13110.1 - 0.0025 18.2 2.2 0.016 15.6 0.9 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3624) PRRSV_2b PF07069.11 CBY13110.1 - 0.12 12.9 2.3 6.1 7.4 1.3 2.9 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Thioredoxin PF00085.20 CBY13112.1 - 2.4e-40 136.7 0.0 1.5e-23 82.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CBY13112.1 - 1.5e-12 47.8 0.0 4.8e-11 42.9 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY13112.1 - 1.7e-10 41.3 1.7 3.6e-06 27.4 0.1 3.6 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY13112.1 - 3.4e-09 36.9 0.0 0.00035 20.8 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CBY13112.1 - 3e-08 33.7 0.3 0.0051 17.0 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CBY13112.1 - 0.002 18.0 0.1 2.2 8.2 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 CBY13112.1 - 0.015 15.1 0.0 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Redoxin PF08534.10 CBY13112.1 - 0.029 14.1 0.2 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Redoxin Thioredoxin_4 PF13462.6 CBY13112.1 - 0.039 14.1 1.2 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin zf_CCCH_5 PF18384.1 CBY13112.1 - 0.045 13.9 0.5 0.045 13.9 0.5 1.9 2 0 0 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) OST3_OST6 PF04756.13 CBY13112.1 - 0.17 11.2 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family ERAP1_C PF11838.8 CBY13113.1 - 9.1e-28 97.7 0.2 1.1e-27 97.5 0.2 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DCX PF03607.17 CBY13114.1 - 1.8e-11 44.0 0.0 0.016 15.3 0.0 3.6 3 0 0 3 3 3 3 Doublecortin KHA PF11834.8 CBY13114.1 - 0.0058 16.7 0.3 0.19 11.9 0.0 3.2 3 1 1 4 4 4 1 KHA, dimerisation domain of potassium ion channel OAF PF14941.6 CBY13114.1 - 0.025 14.0 0.2 0.047 13.1 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Pox_F11 PF04943.12 CBY13114.1 - 0.26 10.3 1.5 0.45 9.5 1.5 1.3 1 0 0 1 1 1 0 Poxvirus F11 protein Ricin_B_lectin PF00652.22 CBY13115.1 - 0.0076 16.5 1.9 0.045 14.0 0.1 2.8 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain MRP-S34 PF16053.5 CBY13116.1 - 0.019 14.6 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 TSP_1 PF00090.19 CBY13117.1 - 1.3e-10 41.3 16.3 2.4e-06 27.7 1.9 2.6 2 0 0 2 2 2 2 Thrombospondin type 1 domain Kelch_2 PF07646.15 CBY13117.1 - 1.4e-07 31.2 0.1 0.028 14.4 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY13117.1 - 5.7e-07 29.6 0.0 0.36 11.2 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY13117.1 - 9.4e-06 25.6 0.3 0.096 12.7 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Baculo_PEP_C PF04513.12 CBY13117.1 - 4.3e-05 23.6 15.2 0.004 17.2 0.1 4.5 1 1 4 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_1 PF01344.25 CBY13117.1 - 0.00031 20.2 0.1 0.017 14.7 0.0 2.9 3 0 0 3 3 3 1 Kelch motif JAKMIP_CC3 PF16034.5 CBY13117.1 - 0.0056 16.7 7.4 0.51 10.3 0.1 2.7 2 1 0 2 2 2 2 JAKMIP CC3 domain IL11 PF07400.11 CBY13117.1 - 0.028 14.1 0.2 0.27 10.9 0.1 2.4 2 1 1 3 3 3 0 Interleukin 11 YtxH PF12732.7 CBY13117.1 - 0.031 14.8 6.1 0.055 14.0 0.6 3.8 3 2 0 3 3 3 0 YtxH-like protein DUF4407 PF14362.6 CBY13117.1 - 0.032 13.6 7.8 0.034 13.5 0.9 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) V-ATPase_G PF03179.15 CBY13117.1 - 0.061 13.9 0.2 0.38 11.3 0.2 2.3 2 0 0 2 2 1 0 Vacuolar (H+)-ATPase G subunit Gp-FAR-1 PF05823.12 CBY13117.1 - 0.066 13.6 3.3 5.3 7.4 0.1 2.7 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CLZ PF16526.5 CBY13117.1 - 0.11 12.9 4.2 3.7 8.0 0.2 4.7 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 CBY13117.1 - 0.11 12.6 14.0 7.5 6.6 0.1 5.0 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF2884 PF11101.8 CBY13117.1 - 0.12 11.9 10.3 0.12 11.9 6.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Apolipoprotein PF01442.18 CBY13117.1 - 0.13 12.2 10.7 0.25 11.2 3.6 3.5 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 CBY13117.1 - 0.15 12.5 17.3 0.19 12.2 0.4 5.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 CBY13117.1 - 0.18 12.1 5.7 2 8.7 0.1 3.8 4 1 1 5 5 4 0 ABC transporter C-terminal domain Kelch_5 PF13854.6 CBY13117.1 - 0.2 11.7 0.4 27 4.9 0.0 2.8 3 0 0 3 3 2 0 Kelch motif Vps5 PF09325.10 CBY13117.1 - 0.28 10.7 8.7 0.33 10.5 0.0 3.8 2 2 2 4 4 4 0 Vps5 C terminal like DUF16 PF01519.16 CBY13117.1 - 0.29 11.7 19.7 50 4.5 9.9 5.2 2 1 2 4 4 4 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 CBY13117.1 - 0.31 11.4 16.7 1.3 9.3 0.6 5.5 5 2 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 CBY13117.1 - 1.1 9.7 12.5 20 5.7 0.2 6.1 6 2 2 8 8 7 0 Flagella accessory protein C (FlaC) ApoLp-III PF07464.11 CBY13117.1 - 1.3 9.1 9.5 0.54 10.3 2.2 3.3 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Retrotran_gag_2 PF14223.6 CBY13117.1 - 1.9 8.2 4.9 27 4.4 0.1 3.6 4 0 0 4 4 4 0 gag-polypeptide of LTR copia-type XhlA PF10779.9 CBY13117.1 - 2.3 8.5 14.3 4.8 7.5 0.1 4.8 4 2 1 5 5 5 0 Haemolysin XhlA DUF883 PF05957.13 CBY13117.1 - 3.8 8.2 6.5 1.7 9.3 0.2 3.4 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Laminin_II PF06009.12 CBY13117.1 - 8.6 6.4 15.9 6.6 6.8 0.3 4.5 3 1 2 5 5 5 0 Laminin Domain II Zot PF05707.12 CBY13118.1 - 0.078 12.6 7.8 0.32 10.6 0.4 3.7 4 0 0 4 4 4 0 Zonular occludens toxin (Zot) YqjK PF13997.6 CBY13118.1 - 2.8 8.3 4.4 2.3 8.5 0.2 2.9 3 0 0 3 3 3 0 YqjK-like protein Rad60-SLD PF11976.8 CBY13119.1 - 1.3e-07 31.3 4.6 1.3e-07 31.3 4.6 2.6 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY13119.1 - 0.0012 18.5 4.6 0.0089 15.8 1.6 3.1 2 1 0 2 2 2 1 Ubiquitin family Fungal_TACC PF12709.7 CBY13119.1 - 0.025 15.0 4.1 0.025 15.0 4.1 2.7 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2203 PF09969.9 CBY13119.1 - 0.15 12.8 6.0 0.32 11.7 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 CBY13119.1 - 0.15 12.1 14.6 0.23 11.5 14.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tweety PF04906.13 CBY13119.1 - 0.21 10.2 0.3 0.26 9.9 0.3 1.1 1 0 0 1 1 1 0 Tweety Spc7 PF08317.11 CBY13119.1 - 0.33 9.8 15.8 0.4 9.5 15.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Sds3 PF08598.11 CBY13119.1 - 0.34 10.9 10.4 0.036 14.1 4.3 2.0 1 1 1 2 2 2 0 Sds3-like DUF1664 PF07889.12 CBY13119.1 - 0.63 10.1 5.1 0.4 10.7 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1151 PF06625.11 CBY13119.1 - 0.72 9.8 15.7 0.35 10.8 13.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) TMPIT PF07851.13 CBY13119.1 - 0.96 8.6 6.8 1.1 8.4 6.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 CBY13119.1 - 2.6 7.0 8.5 3.1 6.8 8.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ThiS PF02597.20 CBY13119.1 - 3.2 8.5 6.2 5.1 7.8 3.1 2.6 1 1 1 2 2 2 0 ThiS family YabA PF06156.13 CBY13119.1 - 6.1 7.5 13.7 14 6.4 5.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 CBY13119.1 - 6.6 6.9 8.6 8.9 6.5 8.1 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Ribosomal_L11_N PF03946.14 CBY13122.1 - 2.5e-22 78.5 0.2 3.8e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBY13122.1 - 2.1e-15 57.0 0.2 3e-15 56.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SNARE PF05739.19 CBY13123.1 - 7.4e-17 61.1 3.7 1.2e-16 60.4 3.7 1.4 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CBY13123.1 - 2.5e-05 24.0 0.3 2.5e-05 24.0 0.3 1.9 2 0 0 2 2 2 1 Syntaxin DUF4448 PF14610.6 CBY13123.1 - 0.013 15.3 0.2 0.013 15.3 0.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) HsdM_N PF12161.8 CBY13123.1 - 0.013 16.1 0.2 0.016 15.8 0.2 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain Orf78 PF06024.12 CBY13123.1 - 0.017 15.4 1.0 0.017 15.4 1.0 1.5 1 1 1 2 2 2 0 Orf78 (ac78) DUF2207 PF09972.9 CBY13123.1 - 0.019 13.8 0.5 0.021 13.6 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Synaptobrevin PF00957.21 CBY13123.1 - 0.029 14.1 7.7 0.053 13.3 7.7 1.4 1 1 0 1 1 1 0 Synaptobrevin Prominin PF05478.11 CBY13123.1 - 0.036 12.0 1.6 0.041 11.9 1.6 1.1 1 0 0 1 1 1 0 Prominin Stevor PF17410.2 CBY13123.1 - 0.051 13.1 0.6 0.055 13.0 0.6 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2615 PF11027.8 CBY13123.1 - 0.071 13.3 0.2 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF3099 PF11298.8 CBY13123.1 - 0.077 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) DotU PF09850.9 CBY13123.1 - 0.091 12.5 0.4 0.18 11.5 0.1 1.6 2 0 0 2 2 2 0 Type VI secretion system protein DotU RIFIN PF02009.16 CBY13123.1 - 0.14 12.0 3.0 0.17 11.7 3.0 1.1 1 0 0 1 1 1 0 Rifin DUF1515 PF07439.11 CBY13123.1 - 0.16 12.0 1.8 4.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Amnionless PF14828.6 CBY13123.1 - 0.2 10.4 0.8 0.22 10.3 0.8 1.1 1 0 0 1 1 1 0 Amnionless DUF2116 PF09889.9 CBY13123.1 - 0.21 11.6 1.0 0.39 10.7 1.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) T2SSF PF00482.23 CBY13123.1 - 0.77 9.7 4.0 1.5 8.8 4.0 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Sigma_reg_N PF13800.6 CBY13123.1 - 1.5 9.2 6.2 2.3 8.6 5.0 1.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Complex1_LYR PF05347.15 CBY13124.1 - 0.00016 21.7 0.2 0.00023 21.1 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ING PF12998.7 CBY13124.1 - 0.066 13.8 2.1 0.15 12.7 2.1 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding YqeY PF09424.10 CBY13124.1 - 0.087 12.9 1.3 0.13 12.3 1.3 1.2 1 0 0 1 1 1 0 Yqey-like protein EF-hand_1 PF00036.32 CBY13125.1 - 2.4e-05 23.5 0.1 7.3e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY13125.1 - 2.6e-05 24.6 5.2 0.0038 17.6 0.8 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY13125.1 - 0.00013 21.3 0.0 0.0003 20.1 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBY13125.1 - 0.00061 19.5 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain CotH PF08757.11 CBY13125.1 - 0.0099 15.4 2.9 0.082 12.4 1.6 2.0 1 1 1 2 2 2 1 CotH kinase protein Ras PF00071.22 CBY13126.1 - 1.5e-45 154.7 0.0 1.7e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY13126.1 - 6e-23 81.3 0.0 8.5e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY13126.1 - 2.7e-09 36.7 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY13126.1 - 6.6e-05 22.5 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain zf-CCCH PF00642.24 CBY13127.1 - 2e-07 30.8 5.8 3.1e-07 30.1 5.8 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY13127.1 - 1e-05 25.4 10.1 1.5e-05 24.8 10.1 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBY13127.1 - 2.5e-05 24.0 5.1 3.5e-05 23.5 5.1 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBY13127.1 - 0.00047 20.8 0.0 0.00047 20.8 0.0 3.0 2 1 1 3 3 3 1 Torus domain zf-CCCH_2 PF14608.6 CBY13127.1 - 0.037 14.5 1.2 0.06 13.8 1.2 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger SR-25 PF10500.9 CBY13127.1 - 5.3 6.6 85.8 3.5 7.2 51.9 2.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein UQ_con PF00179.26 CBY13128.1 - 3e-41 140.4 0.0 3.9e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY13128.1 - 3.4e-07 30.0 0.0 5.4e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBY13128.1 - 0.0039 17.5 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 RWD domain UBA PF00627.31 CBY13128.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain UBA_3 PF09288.10 CBY13128.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Bromodomain PF00439.25 CBY13129.1 - 2.1e-19 69.4 0.1 4.7e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain X PF00739.19 CBY13129.1 - 0.04 14.1 1.2 0.22 11.6 1.2 2.3 1 0 0 1 1 1 0 Trans-activation protein X SH3_1 PF00018.28 CBY13130.1 - 2.4e-11 43.0 0.1 3.1e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY13130.1 - 6.8e-07 29.1 0.0 8.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY13130.1 - 0.0073 16.0 0.0 0.0097 15.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain Pkinase_Tyr PF07714.17 CBY13131.1 - 6.9e-94 313.9 0.0 8.4e-94 313.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY13131.1 - 4.8e-48 163.8 0.0 6.5e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CBY13131.1 - 6.6e-14 51.8 0.0 1.4e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Kdo PF06293.14 CBY13131.1 - 0.0028 17.0 0.1 0.0051 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2059 PF09832.9 CBY13131.1 - 0.016 15.3 0.2 0.034 14.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) Haspin_kinase PF12330.8 CBY13131.1 - 0.037 13.0 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ion_trans_2 PF07885.16 CBY13132.1 - 4.3e-34 116.3 27.5 1.7e-20 72.8 3.2 2.8 2 1 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CBY13132.1 - 2.2e-05 23.8 12.7 0.005 16.1 0.2 2.2 2 0 0 2 2 2 2 Ion transport protein Phytoreo_S7 PF07236.11 CBY13132.1 - 0.23 9.8 0.0 0.29 9.4 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein DUF21 PF01595.20 CBY13132.1 - 0.71 9.6 3.9 0.61 9.8 1.2 1.9 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain DMT_6 PF04342.12 CBY13132.1 - 1.8 8.8 6.0 0.18 12.0 1.4 1.7 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) IRK PF01007.20 CBY13132.1 - 5.1 6.9 11.6 1.5 8.7 0.2 3.6 3 2 2 5 5 5 0 Inward rectifier potassium channel transmembrane domain CUB PF00431.20 CBY13133.1 - 0.0003 21.1 0.1 0.00042 20.6 0.1 1.3 1 0 0 1 1 1 1 CUB domain LAX PF15681.5 CBY13133.1 - 0.05 12.4 0.1 0.084 11.7 0.1 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X Phytochelatin_C PF09328.10 CBY13134.1 - 0.0057 16.0 0.3 0.0091 15.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1984) E1-E2_ATPase PF00122.20 CBY13135.1 - 1.5e-28 99.6 1.4 2.6e-28 98.8 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBY13135.1 - 3.5e-19 69.9 0.0 1.8e-09 38.2 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 CBY13135.1 - 2.8e-10 40.3 0.4 1.3e-09 38.3 0.4 2.1 1 1 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 CBY13135.1 - 5.5e-08 32.4 0.0 1.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CBY13135.1 - 5.3e-06 26.4 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBY13135.1 - 0.01 15.6 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Torus PF16131.5 CBY13136.1 - 4.8e-05 24.0 0.1 7.5e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 CBY13136.1 - 0.022 14.6 6.5 0.031 14.1 6.5 1.2 1 0 0 1 1 1 0 CCCH-type zinc finger Tyr_Deacylase PF02580.16 CBY13137.1 - 5.5e-52 176.1 0.1 6.1e-52 176.0 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase RhoGAP-FF1 PF16512.5 CBY13137.1 - 0.094 13.4 0.1 0.23 12.1 0.0 1.7 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain RRM_DME PF15628.6 CBY13138.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RRM in Demeter MCD PF05292.11 CBY13138.1 - 0.1 12.2 0.0 0.93 9.0 0.0 2.2 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain DUF3970 PF13113.6 CBY13138.1 - 0.13 12.5 0.9 1.6 9.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) HAD_2 PF13419.6 CBY13139.1 - 7.4e-21 75.0 0.0 8.7e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY13139.1 - 7.2e-10 39.5 0.0 1.7e-08 35.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CBY13139.1 - 0.011 15.8 0.0 8 6.6 0.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY13139.1 - 0.028 14.5 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like CoA_trans PF01144.23 CBY13140.1 - 4.7e-118 392.3 5.4 7.3e-75 251.1 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 CBY13140.1 - 0.00074 18.0 0.0 0.0011 17.4 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 CBY13140.1 - 0.062 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Mito_carr PF00153.27 CBY13142.1 - 1e-47 160.0 7.4 1e-21 76.7 0.1 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 CBY13142.1 - 0.2 10.8 3.4 23 4.0 3.4 2.8 1 1 0 1 1 1 0 Gammaproteobacterial serine protease TMA7 PF09072.10 CBY13143.1 - 5.9e-24 84.7 22.7 6.5e-24 84.5 22.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 NKAIN PF05640.14 CBY13144.1 - 2.7e-10 39.8 0.7 2.7e-10 39.8 0.7 1.5 2 0 0 2 2 2 1 Na,K-Atpase Interacting protein DKNYY PF13644.6 CBY13144.1 - 0.077 13.8 0.2 2.6 8.8 0.0 2.3 1 1 1 2 2 2 0 DKNYY family Fungal_lectin_2 PF18647.1 CBY13145.1 - 0.032 14.7 0.5 0.065 13.7 0.5 1.6 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin Dynein_light PF01221.18 CBY13145.1 - 0.12 12.7 0.6 0.12 12.7 0.6 2.1 2 0 0 2 2 2 0 Dynein light chain type 1 Phospholip_A2_1 PF00068.19 CBY13147.1 - 4.9e-14 52.8 6.5 4.9e-14 52.8 6.5 1.7 1 1 0 1 1 1 1 Phospholipase A2 AMP-binding PF00501.28 CBY13148.1 - 3.6e-34 118.1 0.2 4.9e-34 117.6 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY13148.1 - 0.13 13.2 0.0 0.38 11.8 0.0 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Phospholip_A2_1 PF00068.19 CBY13149.1 - 1.3e-17 64.2 8.8 1.3e-17 64.2 8.8 1.7 2 0 0 2 2 2 1 Phospholipase A2 PCB_OB PF17092.5 CBY13154.1 - 0.0091 16.7 1.7 0.0091 16.7 1.7 2.0 1 1 1 2 2 2 1 Penicillin-binding protein OB-like domain Herpes_UL6 PF01763.16 CBY13154.1 - 1.1 7.6 15.2 0.86 8.0 14.1 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like Asp-B-Hydro_N PF05279.11 CBY13154.1 - 8.4 6.4 24.2 10 6.1 24.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Kinesin PF00225.23 CBY13155.1 - 5.4e-109 364.1 0.1 5.4e-109 364.1 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY13155.1 - 1.5e-28 99.6 1.1 5.4e-28 97.8 0.1 2.5 2 0 0 2 2 2 1 Microtubule binding RPAP1_N PF08621.10 CBY13155.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.8 2 0 0 2 2 2 0 RPAP1-like, N-terminal CEP209_CC5 PF16574.5 CBY13155.1 - 1.9 8.7 15.0 2 8.6 0.4 4.0 4 0 0 4 4 4 0 Coiled-coil region of centrosome protein CE290 ASD2 PF08687.11 CBY13155.1 - 5.6 6.4 22.0 7.8 6.0 14.8 2.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 COesterase PF00135.28 CBY13156.1 - 2.1e-59 201.8 0.0 2.3e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY13156.1 - 0.0028 17.5 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY13156.1 - 0.15 11.5 0.5 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Phospholip_A2_1 PF00068.19 CBY13157.1 - 6.8e-16 58.7 8.5 6.8e-16 58.7 8.5 1.8 2 0 0 2 2 2 1 Phospholipase A2 Cyclin_N PF00134.23 CBY13158.1 - 1.5e-36 125.0 1.6 1.2e-35 122.1 0.4 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY13158.1 - 3.5e-23 82.0 1.3 6.7e-23 81.0 0.4 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain PNP_UDP_1 PF01048.20 CBY13159.1 - 1.3e-38 132.5 0.0 1.5e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF1064 PF06356.11 CBY13159.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) WD40 PF00400.32 CBY13160.1 - 6.5e-23 80.6 14.9 1.2e-07 32.2 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY13160.1 - 1.3e-09 38.2 0.0 0.011 16.0 0.0 4.3 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY13160.1 - 7.6e-05 21.8 0.2 0.061 12.3 0.0 2.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBY13160.1 - 0.0019 17.6 0.0 0.014 14.7 0.0 1.9 1 1 0 2 2 2 1 WD40-like domain FEZ PF07763.13 CBY13161.1 - 0.0012 18.6 0.2 0.0015 18.3 0.2 1.1 1 0 0 1 1 1 1 FEZ-like protein FAS_N PF17828.1 CBY13161.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta His_Phos_1 PF00300.22 CBY13162.1 - 1.6e-29 103.0 0.0 1.9e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) XPG_I_2 PF12813.7 CBY13163.1 - 0.0014 18.1 0.0 0.0046 16.5 0.0 1.8 1 0 0 1 1 1 1 XPG domain containing DUF5615 PF18480.1 CBY13163.1 - 0.097 12.4 0.1 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) FadA PF09403.10 CBY13164.1 - 0.016 15.7 0.3 0.025 15.0 0.2 1.5 1 1 0 1 1 1 0 Adhesion protein FadA Sigma70_ner PF04546.13 CBY13165.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_L13 PF00572.18 CBY13166.1 - 2.8e-20 72.8 0.0 6.1e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L13 Clat_adaptor_s PF01217.20 CBY13167.1 - 2.2e-59 199.5 7.5 2.4e-59 199.4 7.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Nse4_C PF08743.10 CBY13168.1 - 8e-09 35.6 0.4 2.5e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Nse4 C-terminal DUF4252 PF14060.6 CBY13168.1 - 0.012 15.6 0.8 0.05 13.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) Pkinase_Tyr PF07714.17 CBY13170.1 - 2.1e-85 286.2 0.0 3.1e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY13170.1 - 3.4e-40 138.1 0.0 5.6e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CBY13170.1 - 1.4e-18 66.8 1.0 1.5e-17 63.5 0.2 2.6 2 0 0 2 2 2 1 SH2 domain Kdo PF06293.14 CBY13170.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F_actin_bind PF08919.10 CBY13170.1 - 0.041 14.0 2.0 0.066 13.3 0.6 2.1 2 0 0 2 2 2 0 F-actin binding Cadherin_C_2 PF16492.5 CBY13171.1 - 0.0018 18.9 0.5 5.1 7.9 0.0 3.1 2 1 0 2 2 2 2 Cadherin cytoplasmic C-terminal 7tm_3 PF00003.22 CBY13171.1 - 0.0028 17.4 1.6 0.0034 17.2 1.6 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR COX1 PF00115.20 CBY13171.1 - 0.0093 14.9 3.3 0.012 14.5 3.3 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF1980 PF09323.10 CBY13171.1 - 0.042 13.8 1.1 0.062 13.2 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SepA PF17080.5 CBY13171.1 - 0.47 10.8 7.3 0.1 13.0 3.8 1.6 2 0 0 2 2 2 0 Multidrug Resistance efflux pump DUF4149 PF13664.6 CBY13171.1 - 1.8 8.9 6.0 0.38 11.1 1.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF3671 PF12420.8 CBY13171.1 - 4 7.5 8.6 6.9 6.8 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function Colicin_V PF02674.16 CBY13171.1 - 7.8 6.5 8.6 0.36 10.8 2.2 2.0 2 1 0 2 2 2 0 Colicin V production protein RRM_1 PF00076.22 CBY13172.1 - 1.3e-25 89.0 0.0 5.3e-13 48.6 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY13172.1 - 3e-06 26.8 0.0 0.00024 20.7 0.1 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY13172.1 - 1.9e-05 24.4 0.0 0.069 13.0 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBY13172.1 - 0.068 13.2 0.1 3 8.0 0.0 2.7 2 2 0 2 2 2 0 Limkain b1 Dus PF01207.17 CBY13173.1 - 1.1e-45 156.1 0.5 3.2e-45 154.5 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) tRNA_m1G_MT PF01746.21 CBY13173.1 - 2.5e-19 69.7 0.1 1.7e-18 67.0 0.0 2.3 3 0 0 3 3 3 1 tRNA (Guanine-1)-methyltransferase His_biosynth PF00977.21 CBY13173.1 - 0.0079 15.7 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein DUF2161 PF09929.9 CBY13173.1 - 0.16 12.1 3.7 0.36 10.9 3.7 1.6 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) NINJA_B PF16136.5 CBY13173.1 - 0.44 10.9 11.9 0.8 10.1 11.9 1.4 1 0 0 1 1 1 0 Putative nuclear localisation signal Paramyxo_ncap PF00973.19 CBY13173.1 - 1.6 7.5 5.7 2.3 7.1 5.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NAD_Gly3P_dh_N PF01210.23 CBY13174.1 - 4.7e-48 163.1 0.7 1e-47 162.0 0.3 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CBY13174.1 - 1.3e-46 158.4 0.0 8.8e-46 155.7 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CBY13174.1 - 0.039 14.5 1.3 0.86 10.2 1.3 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 CBY13174.1 - 0.05 13.2 1.3 1.1 8.8 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Complex1_LYR PF05347.15 CBY13175.1 - 5.1e-09 36.0 0.2 1.3e-08 34.8 0.2 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBY13175.1 - 0.009 16.7 0.0 0.016 15.9 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Peptidase_C65 PF10275.9 CBY13176.1 - 1e-57 195.5 0.8 1.2e-57 195.2 0.8 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 CBY13176.1 - 7.1e-05 23.3 0.0 0.00027 21.4 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease AAA PF00004.29 CBY13177.1 - 2.5e-43 147.7 0.0 4.5e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY13177.1 - 7.7e-10 38.4 0.2 1.8e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CBY13177.1 - 1.4e-09 37.8 0.0 3.6e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CBY13177.1 - 5.3e-08 33.4 0.1 5e-05 23.8 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CBY13177.1 - 4.3e-06 26.8 0.2 0.00018 21.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY13177.1 - 4.6e-06 26.9 1.0 0.0013 19.0 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.14 CBY13177.1 - 8e-06 26.1 0.0 4.5e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CBY13177.1 - 1.2e-05 25.1 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBY13177.1 - 0.00087 19.8 0.0 0.0064 17.0 0.0 2.4 3 0 0 3 3 2 1 AAA domain Prot_ATP_OB_N PF17758.1 CBY13177.1 - 0.001 18.6 0.3 0.0028 17.3 0.1 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 CBY13177.1 - 0.0013 18.9 0.0 0.0043 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CBY13177.1 - 0.0026 17.0 0.0 0.0063 15.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 CBY13177.1 - 0.003 17.4 1.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBY13177.1 - 0.0032 17.2 0.1 0.011 15.5 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CBY13177.1 - 0.0036 16.8 0.0 0.0076 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 CBY13177.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBY13177.1 - 0.008 16.6 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CBY13177.1 - 0.0087 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBY13177.1 - 0.0092 15.8 0.0 0.033 14.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CBY13177.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CBY13177.1 - 0.02 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Thymidylate_kin PF02223.17 CBY13177.1 - 0.02 14.6 0.3 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.6 CBY13177.1 - 0.024 14.4 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBY13177.1 - 0.037 13.7 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBY13177.1 - 0.064 13.1 0.8 0.45 10.4 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CBY13177.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 CBY13177.1 - 0.084 12.6 0.0 0.26 11.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 CBY13177.1 - 0.091 12.1 0.4 0.9 8.8 0.0 2.5 2 1 0 3 3 3 0 KaiC CENP-S PF15630.6 CBY13177.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 CENP-S protein AAA_28 PF13521.6 CBY13177.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBY13177.1 - 0.15 11.6 0.2 0.4 10.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain DivIC PF04977.15 CBY13177.1 - 3.9 7.3 7.8 13 5.6 7.8 1.9 1 0 0 1 1 1 0 Septum formation initiator AAA_23 PF13476.6 CBY13177.1 - 5 7.6 7.9 1.1e+02 3.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CBY13178.1 - 3.6e-28 98.6 0.0 6.5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBY13178.1 - 2.3e-09 37.1 0.0 4.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CBY13178.1 - 1.4e-07 32.1 0.1 1.9e-05 25.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CBY13178.1 - 1.9e-05 24.5 0.0 3.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBY13178.1 - 3e-05 24.3 0.4 0.0015 18.8 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.14 CBY13178.1 - 0.00012 22.3 0.0 0.00055 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBY13178.1 - 0.00016 21.7 0.1 0.0019 18.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBY13178.1 - 0.0008 19.6 0.1 0.0027 17.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 CBY13178.1 - 0.0011 18.5 0.1 0.0032 17.1 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 CBY13178.1 - 0.0038 16.4 0.0 0.0079 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 CBY13178.1 - 0.0039 17.0 1.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBY13178.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 CBY13178.1 - 0.0057 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CBY13178.1 - 0.0069 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBY13178.1 - 0.0078 16.6 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CBY13178.1 - 0.0096 15.3 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBY13178.1 - 0.012 16.1 0.0 0.043 14.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 CBY13178.1 - 0.014 15.3 0.0 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CBY13178.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 CBY13178.1 - 0.021 14.5 0.3 3.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Thymidylate kinase TIP49 PF06068.13 CBY13178.1 - 0.025 13.8 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 CBY13178.1 - 0.033 13.9 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBY13178.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBY13178.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 CBY13178.1 - 0.12 12.3 0.9 0.58 10.0 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CBY13178.1 - 0.19 11.3 0.6 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DivIC PF04977.15 CBY13178.1 - 5.1 6.9 7.8 15 5.4 7.8 1.8 1 0 0 1 1 1 0 Septum formation initiator SARAF PF06682.12 CBY13179.1 - 0.74 9.4 5.3 0.52 9.9 0.3 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Prot_ATP_ID_OB PF16450.5 CBY13180.1 - 6.8e-10 38.7 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA PF00004.29 CBY13180.1 - 3.3e-09 37.3 0.0 7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY13180.1 - 3.6e-06 27.5 0.0 2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBY13180.1 - 9.8e-05 22.6 0.1 0.00046 20.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBY13180.1 - 0.00012 22.1 0.0 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 CBY13180.1 - 0.00051 19.6 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 CBY13180.1 - 0.0009 19.4 0.3 0.0048 17.1 0.0 2.2 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CBY13180.1 - 0.00099 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CBY13180.1 - 0.0011 18.9 0.0 0.0045 16.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CBY13180.1 - 0.0013 18.5 0.1 0.0031 17.3 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.6 CBY13180.1 - 0.0017 18.2 1.9 0.077 12.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBY13180.1 - 0.0041 16.9 0.0 0.038 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBY13180.1 - 0.0041 16.5 0.0 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CBY13180.1 - 0.0093 15.5 0.0 0.02 14.4 0.0 1.6 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CBY13180.1 - 0.013 16.0 0.0 0.1 13.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CBY13180.1 - 0.013 15.8 0.0 0.041 14.3 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 CBY13180.1 - 0.044 13.5 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBY13180.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.13 CBY13180.1 - 0.052 12.7 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Thymidylate_kin PF02223.17 CBY13180.1 - 0.053 13.2 0.3 8.6 6.0 0.6 2.3 2 0 0 2 2 2 0 Thymidylate kinase UvrD-helicase PF00580.21 CBY13180.1 - 0.054 13.0 0.0 0.76 9.2 0.1 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ATPase PF06745.13 CBY13180.1 - 0.055 12.8 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 KaiC SKI PF01202.22 CBY13180.1 - 0.056 13.6 1.8 0.75 9.9 0.0 2.6 2 1 1 3 3 3 0 Shikimate kinase AAA_25 PF13481.6 CBY13180.1 - 0.059 12.9 0.3 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBY13180.1 - 0.062 13.2 0.4 0.75 9.7 0.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea TsaE PF02367.17 CBY13180.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CBY13180.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Cytidylate_kin PF02224.18 CBY13180.1 - 0.073 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_13 PF13166.6 CBY13180.1 - 0.099 11.3 3.0 7.1 5.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fmp27_WPPW PF10359.9 CBY13180.1 - 0.18 10.6 2.3 0.2 10.5 2.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain AAA_23 PF13476.6 CBY13180.1 - 0.28 11.7 6.1 42 4.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DivIC PF04977.15 CBY13180.1 - 1.8 8.4 7.8 1.9 8.3 6.5 1.7 2 0 0 2 2 1 0 Septum formation initiator SARAF PF06682.12 CBY13181.1 - 0.37 10.4 5.3 0.34 10.5 0.3 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Aminotran_1_2 PF00155.21 CBY13182.1 - 1.2e-24 87.2 0.0 1.4e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HATPase_c_5 PF14501.6 CBY13182.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 GHKL domain PLAC8 PF04749.17 CBY13183.1 - 5e-18 65.9 11.4 7.7e-18 65.3 11.4 1.2 1 0 0 1 1 1 1 PLAC8 family BacA PF02673.18 CBY13183.1 - 0.059 13.1 0.1 0.074 12.7 0.1 1.1 1 0 0 1 1 1 0 Bacitracin resistance protein BacA PMP22_Claudin PF00822.20 CBY13185.1 - 2.8e-10 40.3 13.3 4.2e-10 39.8 13.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family ATP-gua_Ptrans PF00217.19 CBY13186.1 - 1e-37 129.7 0.4 1.9e-36 125.5 0.4 1.9 1 1 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY13187.1 - 9.9e-19 67.5 0.0 1.6e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF4329 PF14220.6 CBY13187.1 - 0.0036 17.3 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) Pentapeptide PF00805.22 CBY13187.1 - 0.16 11.6 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Galactosyl_T PF01762.21 CBY13189.1 - 2.4e-12 47.1 0.1 1e-11 45.1 0.1 1.8 1 1 0 1 1 1 1 Galactosyltransferase RNA_binding PF01877.17 CBY13191.1 - 0.15 12.3 0.8 0.38 11.0 0.8 1.7 1 0 0 1 1 1 0 RNA binding DUF4611 PF15387.6 CBY13193.1 - 0.0038 17.4 0.2 0.051 13.8 0.1 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4611) Phospholip_A2_1 PF00068.19 CBY13194.1 - 8.2e-19 68.1 6.5 8.2e-19 68.1 6.5 1.6 2 0 0 2 2 2 1 Phospholipase A2 DUF975 PF06161.11 CBY13195.1 - 0.0045 16.8 8.0 0.063 13.1 4.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF975) zf-LITAF-like PF10601.9 CBY13195.1 - 0.0049 17.1 31.4 0.26 11.6 7.8 4.6 4 1 0 4 4 4 4 LITAF-like zinc ribbon domain DPM3 PF08285.11 CBY13195.1 - 0.0062 16.7 3.4 0.71 10.1 0.7 2.5 2 0 0 2 2 2 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TSP_1 PF00090.19 CBY13197.1 - 1.5e-05 25.1 4.6 4.2e-05 23.7 4.6 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain PRANC PF09372.10 CBY13197.1 - 0.055 13.8 0.1 0.23 11.8 0.1 2.2 1 0 0 1 1 1 0 PRANC domain IBN_N PF03810.19 CBY13197.1 - 0.71 9.8 2.9 4.3 7.3 0.0 3.0 3 1 1 4 4 4 0 Importin-beta N-terminal domain CHGN PF05679.16 CBY13198.1 - 2.6e-95 320.2 3.5 3.2e-95 319.9 3.5 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY13198.1 - 6e-17 61.9 0.1 1.1e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 CBY13198.1 - 1.5e-09 37.3 0.4 4.3e-09 35.9 0.4 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY13198.1 - 1.6e-05 24.8 0.1 0.044 13.6 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CBY13198.1 - 4.1e-05 23.2 0.1 0.019 14.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CBY13198.1 - 0.0013 18.2 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 21 Galactosyl_T PF01762.21 CBY13198.1 - 0.0013 18.6 0.0 0.058 13.2 0.0 2.6 2 0 0 2 2 2 1 Galactosyltransferase DUF4618 PF15397.6 CBY13198.1 - 0.013 14.9 0.3 0.029 13.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) MRP_L53 PF10780.9 CBY13198.1 - 0.014 15.6 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 POX PF07526.11 CBY13198.1 - 0.039 14.5 0.0 0.098 13.2 0.0 1.8 1 0 0 1 1 1 0 Associated with HOX Dimer_Tnp_hAT PF05699.14 CBY13199.1 - 3.4e-07 30.0 0.2 5e-07 29.4 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF5383 PF17355.2 CBY13200.1 - 0.0055 17.1 0.1 0.0095 16.3 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5383) UL45 PF05473.12 CBY13200.1 - 0.027 14.1 0.1 0.053 13.2 0.0 1.4 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like SurA_N_3 PF13624.6 CBY13200.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 SurA N-terminal domain Mid2 PF04478.12 CBY13200.1 - 3.1 7.6 6.5 0.5 10.2 1.6 1.8 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Comm PF15957.5 CBY13200.1 - 4.7 7.6 6.7 6.9 7.0 6.7 1.6 1 1 0 1 1 1 0 Commissureless Cupin_8 PF13621.6 CBY13201.1 - 8.9e-25 87.8 0.0 1.2e-24 87.4 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY13201.1 - 0.023 14.2 0.0 0.13 11.7 0.0 2.0 1 1 0 1 1 1 0 Cupin superfamily protein PS_Dcarbxylase PF02666.15 CBY13202.1 - 6.4e-40 136.8 0.0 7.5e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 CBY13202.1 - 0.17 11.8 0.0 0.41 10.6 0.0 1.5 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Pox_D5 PF03288.16 CBY13203.1 - 0.045 14.2 0.3 0.07 13.6 0.3 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF4407 PF14362.6 CBY13203.1 - 0.35 10.2 5.0 0.38 10.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCHC PF00098.23 CBY13204.1 - 0.13 12.4 2.2 0.28 11.3 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CBY13204.1 - 1.8 8.6 6.1 4.4 7.3 6.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Syntaxin_2 PF14523.6 CBY13204.1 - 2.4 8.6 18.6 0.027 14.9 4.9 4.0 3 1 1 4 4 4 0 Syntaxin-like protein DivIC PF04977.15 CBY13204.1 - 3.8 7.3 8.7 2 8.2 2.7 2.9 2 0 0 2 2 2 0 Septum formation initiator zf-LITAF-like PF10601.9 CBY13205.1 - 0.0063 16.8 14.6 0.47 10.8 9.3 2.2 2 0 0 2 2 2 2 LITAF-like zinc ribbon domain U-box PF04564.15 CBY13207.1 - 7.3e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain SRP-alpha_N PF04086.13 CBY13209.1 - 3.5 7.5 16.0 3.9 7.3 16.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Glyco_hydro_2_C PF02836.17 CBY13213.1 - 0.02 14.0 0.0 0.061 12.4 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.25 CBY13214.1 - 3.5e-53 180.7 0.0 2.9e-49 167.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13214.1 - 2.2e-34 118.9 0.0 4.8e-25 88.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBY13214.1 - 1.4e-05 25.1 0.1 0.0017 18.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY13214.1 - 9e-05 21.9 0.0 0.00035 20.0 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY13214.1 - 0.0055 16.1 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY13214.1 - 0.027 13.3 1.0 0.032 13.0 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase GNVR PF13807.6 CBY13214.1 - 0.062 13.2 0.1 0.062 13.2 0.1 2.7 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Seadorna_VP7 PF07387.11 CBY13214.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 CBY13214.1 - 0.072 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF898 PF05987.13 CBY13214.1 - 0.077 12.0 2.6 0.94 8.5 1.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) FTA2 PF13095.6 CBY13214.1 - 0.23 11.1 0.0 2.3 7.8 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Sigma70_r4_2 PF08281.12 CBY13215.1 - 2.7e-11 43.0 0.1 8.1e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 CBY13215.1 - 1.9e-08 33.7 0.0 5e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 CBY13215.1 - 0.0045 16.7 0.1 0.0093 15.7 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 CBY13215.1 - 0.0045 16.9 0.1 0.0081 16.1 0.1 1.3 1 0 0 1 1 1 1 ECF sigma factor HTH_AsnC-type PF13404.6 CBY13215.1 - 0.0094 15.8 0.8 0.22 11.4 0.0 3.0 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain S_4TM PF18159.1 CBY13215.1 - 0.037 13.3 0.4 0.037 13.3 0.4 1.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain HTH_10 PF04967.12 CBY13215.1 - 0.056 13.3 0.2 0.28 11.0 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain PAX PF00292.18 CBY13215.1 - 0.11 12.4 0.0 0.94 9.4 0.0 2.1 2 0 0 2 2 2 0 'Paired box' domain DUF4473 PF14747.6 CBY13215.1 - 0.15 12.7 3.8 3.9 8.1 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4473) PRKG1_interact PF15898.5 CBY13215.1 - 0.58 11.1 4.1 1.3 10.0 1.9 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2681 PF10883.8 CBY13215.1 - 0.85 10.1 5.1 0.15 12.5 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Radical_SAM PF04055.21 CBY13216.1 - 7.3e-25 88.3 0.1 1.2e-24 87.6 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 CBY13216.1 - 1.5e-23 82.7 0.0 2.6e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM_2 PF18693.1 CBY13216.1 - 8.3e-12 45.1 1.8 1e-11 44.8 0.4 1.9 2 0 0 2 2 2 1 TRAM domain TRAM PF01938.20 CBY13216.1 - 0.0034 17.3 0.1 0.0091 16.0 0.1 1.7 1 0 0 1 1 1 1 TRAM domain GFO_IDH_MocA PF01408.22 CBY13217.1 - 6e-14 52.9 0.0 9.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CBY13217.1 - 7e-05 22.8 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 CBY13217.1 - 0.2 12.3 0.1 0.39 11.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Lipase_GDSL_2 PF13472.6 CBY13218.1 - 3.5e-16 60.1 0.0 5.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CBY13218.1 - 3.5e-06 27.1 0.0 8.2e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 CBY13218.1 - 0.086 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 OSK domain DNA_topoisoIV PF00521.20 CBY13219.1 - 1.6e-140 468.8 0.0 2e-140 468.5 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 CBY13219.1 - 8e-69 226.9 17.0 2.8e-12 45.9 0.2 6.7 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller Foamy_virus_ENV PF03408.14 CBY13219.1 - 0.21 9.4 0.0 0.31 8.8 0.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein DNA_gyraseB PF00204.25 CBY13220.1 - 3.9e-56 189.3 0.0 5.8e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 CBY13220.1 - 4.2e-27 94.1 0.4 8.1e-27 93.2 0.4 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 CBY13220.1 - 8.1e-22 77.9 0.0 1.8e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CBY13220.1 - 2.8e-17 62.8 0.0 6.6e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 CBY13220.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol_A_exo1 PF01612.20 CBY13222.1 - 7.7e-32 110.4 0.0 1.1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CBY13222.1 - 6.1e-09 35.7 0.4 5.2e-06 26.4 0.1 2.5 2 0 0 2 2 2 2 HRDC domain Sacchrp_dh_C PF16653.5 CBY13223.1 - 5.4e-36 125.1 0.0 7.3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CBY13223.1 - 6.5e-33 113.8 0.5 1.4e-32 112.7 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CBY13223.1 - 0.00048 20.2 0.3 0.00096 19.2 0.3 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 CBY13223.1 - 0.037 13.4 0.5 0.19 11.0 0.4 2.1 2 0 0 2 2 2 0 ThiF family Ldh_1_N PF00056.23 CBY13223.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ABC_tran PF00005.27 CBY13224.1 - 2.2e-29 102.7 0.0 3.2e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY13224.1 - 8.8e-12 45.4 0.1 1.4e-06 28.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CBY13224.1 - 2.4e-07 31.4 0.0 4.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 CBY13224.1 - 0.0019 17.7 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBY13224.1 - 0.0044 17.5 0.0 0.012 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBY13224.1 - 0.0068 16.1 0.1 0.046 13.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY13224.1 - 0.024 15.0 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CBY13224.1 - 0.043 14.2 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 CBY13224.1 - 0.08 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY13224.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 CBY13224.1 - 0.18 11.5 0.0 2.5 7.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PATR PF12951.7 CBY13225.1 - 8.9e-21 73.7 31.1 9.9e-08 32.0 4.5 31.6 30 7 1 31 31 31 8 Passenger-associated-transport-repeat N_BRCA1_IG PF16158.5 CBY13225.1 - 0.025 15.3 0.0 0.065 14.0 0.0 1.7 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene NPCBM_assoc PF10633.9 CBY13225.1 - 0.15 12.3 3.2 6.2 7.2 0.1 4.3 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FCD PF07729.12 CBY13226.1 - 4.5e-28 98.2 4.3 9.3e-28 97.2 4.3 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 CBY13226.1 - 6.5e-20 70.5 0.3 1.3e-19 69.5 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family DUF977 PF06163.11 CBY13226.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 CBY13226.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 CBY13226.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 CBY13226.1 - 0.088 12.5 0.2 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MadM PF03818.13 CBY13227.1 - 7.8e-27 92.9 4.4 3.8e-26 90.7 4.4 2.3 1 0 0 1 1 1 1 Malonate/sodium symporter MadM subunit SQHop_cyclase_C PF13243.6 CBY13228.1 - 3e-05 23.3 7.4 0.0037 16.4 2.2 2.8 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 CBY13228.1 - 0.041 13.6 9.8 0.11 12.3 0.0 3.7 5 0 0 5 5 5 0 Prenyltransferase and squalene oxidase repeat DivIC PF04977.15 CBY13228.1 - 0.092 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator TM2 PF05154.16 CBY13229.1 - 1.8e-15 57.0 8.5 2.4e-15 56.6 8.5 1.2 1 0 0 1 1 1 1 TM2 domain SH3_2 PF07653.17 CBY13229.1 - 0.013 15.1 0.1 0.036 13.7 0.1 1.7 1 1 0 1 1 1 0 Variant SH3 domain Sensor_TM1 PF13755.6 CBY13229.1 - 0.21 11.4 0.2 0.76 9.6 0.0 1.9 1 1 1 2 2 2 0 Sensor N-terminal transmembrane domain Bac_DNA_binding PF00216.21 CBY13230.1 - 7.2e-29 99.8 2.2 7.8e-29 99.7 2.2 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-CCDC81_euk_1 PF14908.6 CBY13230.1 - 0.02 15.1 0.0 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 HU-HIG PF18291.1 CBY13230.1 - 0.043 13.9 0.1 0.045 13.9 0.1 1.1 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 CBY13230.1 - 0.087 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 EF-hand_5 PF13202.6 CBY13231.1 - 3.9e-17 60.9 4.6 0.00032 20.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_1 PF00036.32 CBY13231.1 - 2e-14 52.0 3.7 0.0074 15.8 0.0 4.1 2 2 2 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY13231.1 - 6.7e-13 47.4 4.6 0.027 14.4 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBY13231.1 - 1e-09 38.7 0.1 0.32 11.5 0.7 3.9 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 CBY13231.1 - 0.00029 20.6 1.6 2.4 8.0 0.1 3.8 3 1 1 4 4 4 2 EF-hand domain pair Dockerin_1 PF00404.18 CBY13231.1 - 0.014 15.6 2.0 14 6.0 0.1 3.4 2 2 1 3 3 3 0 Dockerin type I domain Cro PF09048.10 CBY13231.1 - 0.016 15.2 0.0 12 6.0 0.0 3.2 3 0 0 3 3 3 0 Cro SPARC_Ca_bdg PF10591.9 CBY13231.1 - 0.019 15.3 1.6 22 5.4 0.1 3.3 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region zf-HC2 PF13490.6 CBY13231.1 - 0.05 13.9 5.4 41 4.5 0.2 4.1 4 0 0 4 4 4 0 Putative zinc-finger Toprim_2 PF13155.6 CBY13231.1 - 0.14 12.6 0.5 15 6.1 0.5 3.0 1 1 0 1 1 1 0 Toprim-like Caleosin PF05042.13 CBY13231.1 - 0.25 11.3 0.3 2 8.3 0.0 2.5 2 2 2 4 4 4 0 Caleosin related protein Excalibur PF05901.11 CBY13231.1 - 5.5 7.7 5.9 2.2e+02 2.6 0.3 3.8 4 0 0 4 4 4 0 Excalibur calcium-binding domain EF-hand_5 PF13202.6 CBY13232.1 - 1.6e-10 40.0 9.5 0.00038 19.8 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_1 PF00036.32 CBY13232.1 - 7.3e-10 37.7 4.8 0.087 12.4 0.1 4.1 3 1 1 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY13232.1 - 7.7e-10 37.9 5.3 0.26 11.3 0.0 4.1 3 1 1 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBY13232.1 - 1e-07 32.3 0.2 0.0017 18.8 0.2 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CBY13232.1 - 1.8e-05 24.5 4.7 0.21 11.5 0.4 3.9 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY13232.1 - 4.2e-05 23.8 2.6 3.6 8.0 0.1 3.9 2 2 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Trans_reg_C PF00486.28 CBY13233.1 - 3e-24 84.9 0.0 6.2e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 CBY13233.1 - 3.8e-24 85.0 0.0 9e-24 83.8 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Hist_deacetyl PF00850.19 CBY13235.1 - 8.1e-82 275.1 0.8 1.1e-81 274.7 0.8 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Aminotran_1_2 PF00155.21 CBY13236.1 - 1.3e-43 149.6 0.0 1.8e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CBY13236.1 - 0.00016 20.8 0.0 0.00031 19.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Preseq_ALAS PF09029.10 CBY13236.1 - 0.0037 17.7 0.2 0.0085 16.6 0.2 1.6 1 1 0 1 1 1 1 5-aminolevulinate synthase presequence PapA_C PF16911.5 CBY13236.1 - 0.15 12.1 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus ARPC4 PF05856.12 CBY13237.1 - 9.1e-74 246.6 6.3 1e-73 246.5 6.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) ubiquitin PF00240.23 CBY13238.1 - 2.4e-05 24.0 0.2 4.9e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_3 PF14836.6 CBY13238.1 - 0.041 13.9 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain DnaJ PF00226.31 CBY13239.1 - 3.5e-25 87.9 1.0 8.4e-25 86.7 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 CBY13239.1 - 1.5e-19 70.2 1.3 1.5e-19 70.2 1.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 CBY13239.1 - 0.001 19.0 0.7 0.0061 16.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Mitofilin PF09731.9 CBY13239.1 - 0.025 13.5 0.0 0.025 13.5 0.0 2.8 3 1 0 3 3 3 0 Mitochondrial inner membrane protein RPT PF13446.6 CBY13239.1 - 0.027 14.4 0.0 0.082 12.8 0.0 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein Renin_r PF07850.14 CBY13239.1 - 0.045 14.4 0.1 0.21 12.2 0.0 2.1 2 0 0 2 2 2 0 Renin receptor-like protein TPR_7 PF13176.6 CBY13239.1 - 0.14 12.3 0.4 1.5 9.1 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY13239.1 - 0.29 11.4 5.0 0.84 10.0 0.3 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY13239.1 - 0.6 10.0 4.0 3.8 7.5 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.26 CBY13240.1 - 6.4e-19 67.5 0.0 9.5e-19 66.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family JHBP PF06585.11 CBY13240.1 - 0.071 12.3 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) V-SNARE_C PF12352.8 CBY13241.1 - 1.1e-15 57.7 2.6 3e-14 53.1 1.2 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus MAD PF05557.13 CBY13241.1 - 0.0045 15.4 2.4 0.005 15.3 2.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Sec20 PF03908.13 CBY13241.1 - 0.02 14.8 0.2 0.066 13.1 0.1 1.8 1 1 0 1 1 1 0 Sec20 DHHC PF01529.20 CBY13242.1 - 8e-28 97.2 7.5 8e-28 97.2 7.5 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ras PF00071.22 CBY13243.1 - 6.1e-41 139.7 0.0 6.8e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY13243.1 - 7.7e-25 87.4 0.0 8.7e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY13243.1 - 5.2e-07 29.3 0.0 5.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBY13243.1 - 0.0026 17.2 0.0 0.0033 16.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY13243.1 - 0.0056 16.1 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CBY13243.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 CBY13244.1 - 9.4e-05 22.1 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Pkinase PF00069.25 CBY13245.1 - 1e-63 215.2 0.0 1.4e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13245.1 - 1.1e-28 100.3 0.0 1.8e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY13245.1 - 4.2e-09 36.1 0.0 6.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY13245.1 - 0.00045 19.6 0.8 0.0012 18.2 0.8 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY13245.1 - 0.00068 19.3 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Ribos_L4_asso_C PF14374.6 CBY13245.1 - 0.0036 17.3 0.3 0.0036 17.3 0.3 2.1 3 0 0 3 3 3 1 60S ribosomal protein L4 C-terminal domain FTA2 PF13095.6 CBY13245.1 - 0.039 13.6 0.0 0.074 12.7 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBY13245.1 - 0.078 12.9 0.4 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family SMK-1 PF04802.15 CBY13246.1 - 1.9e-50 171.4 9.1 1.9e-50 171.4 9.1 2.0 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.18 CBY13246.1 - 0.001 19.3 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CBY13246.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 WH1 domain DUF2433 PF10360.9 CBY13246.1 - 0.13 12.4 2.3 4.4 7.4 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2433) DUF3573 PF12097.8 CBY13247.1 - 5.1 5.8 11.0 6.5 5.5 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) APG6_N PF17675.1 CBY13247.1 - 5.9 7.4 18.3 1.6 9.3 14.6 1.9 1 1 0 2 2 2 0 Apg6 coiled-coil region PAP2 PF01569.21 CBY13249.1 - 9e-24 83.8 0.4 3.5e-23 81.9 0.4 1.9 1 1 0 1 1 1 1 PAP2 superfamily Cation_efflux PF01545.21 CBY13249.1 - 0.00025 20.8 0.0 0.019 14.7 0.1 2.1 2 0 0 2 2 2 2 Cation efflux family DUF4234 PF14018.6 CBY13249.1 - 0.015 15.4 0.6 0.054 13.6 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF485 PF04341.12 CBY13249.1 - 0.16 11.9 0.7 16 5.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ATP_transf PF09830.9 CBY13250.1 - 0.14 12.4 0.2 3.2 8.0 0.0 2.3 2 0 0 2 2 2 0 ATP adenylyltransferase Enkurin PF13864.6 CBY13251.1 - 6.4e-24 84.2 1.6 7.1e-24 84.1 1.6 1.0 1 0 0 1 1 1 1 Calmodulin-binding Cob_adeno_trans PF01923.18 CBY13251.1 - 0.065 13.4 0.1 0.074 13.2 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IDEAL PF08858.10 CBY13251.1 - 1.6 8.5 6.3 36 4.2 0.1 3.5 4 0 0 4 4 4 0 IDEAL domain ABC_tran_CTD PF16326.5 CBY13251.1 - 5 7.5 11.8 0.92 9.8 1.2 2.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain SecE PF00584.20 CBY13252.1 - 5.6e-14 51.8 0.2 6.3e-14 51.6 0.2 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Zona_pellucida PF00100.23 CBY13253.1 - 1.1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Zona pellucida-like domain Podoplanin PF05808.11 CBY13254.1 - 2.9e-05 24.2 2.6 3.9e-05 23.8 2.6 1.2 1 0 0 1 1 1 1 Podoplanin Alpha_GJ PF03229.13 CBY13254.1 - 0.00069 20.2 3.3 0.0011 19.5 3.3 1.3 1 0 0 1 1 1 1 Alphavirus glycoprotein J Myc_N PF01056.18 CBY13254.1 - 0.0017 18.3 2.4 0.0019 18.1 2.4 1.1 1 0 0 1 1 1 1 Myc amino-terminal region DUF4366 PF14283.6 CBY13254.1 - 0.0032 17.5 0.7 0.0052 16.8 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) Miga PF10265.9 CBY13254.1 - 0.0038 16.3 2.5 0.0041 16.2 2.5 1.1 1 0 0 1 1 1 1 Mitoguardin Apt1 PF10351.9 CBY13254.1 - 0.019 13.8 1.8 0.02 13.7 1.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4667 PF15700.5 CBY13254.1 - 0.032 14.3 12.0 0.048 13.8 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) BES1_N PF05687.13 CBY13254.1 - 0.036 14.5 9.3 0.061 13.7 9.3 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal DUF5305 PF17231.2 CBY13254.1 - 0.044 13.2 3.7 0.077 12.4 3.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) MGC-24 PF05283.11 CBY13254.1 - 0.045 14.2 8.1 0.075 13.5 8.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 CBY13254.1 - 0.12 12.3 9.1 0.33 10.9 9.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family PI3K_1B_p101 PF10486.9 CBY13254.1 - 0.13 10.0 6.4 0.15 9.8 6.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit YebO PF13974.6 CBY13254.1 - 0.58 10.3 3.6 3.3 7.8 0.0 3.0 3 1 0 3 3 3 0 YebO-like protein Herpes_capsid PF06112.11 CBY13254.1 - 3.2 7.8 14.0 4.6 7.3 14.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Presenilin PF01080.17 CBY13254.1 - 3.4 6.3 7.1 1.9 7.2 4.3 1.7 2 0 0 2 2 2 0 Presenilin Macoilin PF09726.9 CBY13254.1 - 3.4 6.1 8.2 4.3 5.8 8.2 1.1 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 CBY13254.1 - 4.6 6.2 14.5 7.2 5.6 13.6 1.7 2 0 0 2 2 2 0 Protein family FAM199X ADH_zinc_N PF00107.26 CBY13255.1 - 1e-11 44.9 0.0 2.5e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBY13255.1 - 7.2e-09 35.5 0.3 6.2e-08 32.5 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CBY13255.1 - 1.8e-07 32.3 0.0 3.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase VWD PF00094.25 CBY13256.1 - 1.7e-25 90.1 0.1 2.5e-25 89.6 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 CBY13256.1 - 3.8e-08 33.6 0.5 3.8e-08 33.6 0.5 2.1 2 0 0 2 2 2 1 C8 domain Somatomedin_B PF01033.17 CBY13256.1 - 2.3e-05 24.7 21.3 0.00011 22.5 21.3 2.3 1 0 0 1 1 1 1 Somatomedin B domain LRR_6 PF13516.6 CBY13257.1 - 5.5e-21 72.8 14.9 0.023 14.7 0.0 8.5 8 0 0 8 8 8 7 Leucine Rich repeat LRR_1 PF00560.33 CBY13257.1 - 0.00019 21.5 11.3 4 8.4 0.0 7.2 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 CBY13257.1 - 0.074 13.5 22.1 0.69 10.4 1.4 5.5 1 1 6 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY13257.1 - 0.21 11.4 20.1 0.48 10.2 3.8 5.6 3 1 3 6 6 6 0 Leucine rich repeat Nucleoside_tran PF01733.18 CBY13258.1 - 3.5e-18 66.0 1.5 3.5e-18 66.0 1.5 2.3 2 0 0 2 2 2 1 Nucleoside transporter Sigma70_r4_2 PF08281.12 CBY13258.1 - 0.026 14.2 0.0 0.073 12.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Trypsin PF00089.26 CBY13259.1 - 0.0016 18.3 0.4 0.0025 17.7 0.4 1.1 1 0 0 1 1 1 1 Trypsin CENP-T_C PF15511.6 CBY13260.1 - 3.3e-08 33.6 0.1 4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY13260.1 - 4.7e-05 23.5 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY13260.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY13260.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY13260.1 - 0.00033 21.0 0.2 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY13260.1 - 0.012 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY13260.1 - 0.046 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY13260.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RT_RNaseH_2 PF17919.1 CBY13261.1 - 3.1e-23 81.7 0.0 7.1e-23 80.5 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY13261.1 - 2.1e-13 50.5 0.0 4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Lactamase_B_6 PF16661.5 CBY13261.1 - 0.0052 16.2 0.0 0.0083 15.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain DNA_pol_viral_C PF00336.18 CBY13261.1 - 0.016 14.7 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain V_ATPase_I PF01496.19 CBY13262.1 - 0.0086 14.1 8.7 0.01 13.8 8.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CCDC85 PF10226.9 CBY13262.1 - 0.72 9.5 7.4 0.38 10.4 5.5 1.5 1 1 0 1 1 1 0 CCDC85 family Striatin PF08232.12 CBY13262.1 - 1.6 9.3 11.0 0.24 12.0 4.9 2.1 1 1 1 2 2 2 0 Striatin family ENTH PF01417.20 CBY13263.1 - 7.6e-47 158.5 0.1 8.8e-47 158.3 0.1 1.0 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 CBY13263.1 - 7.8e-05 22.5 0.0 9.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 VHS domain ANTH PF07651.16 CBY13263.1 - 8.1e-05 21.7 0.0 9.5e-05 21.5 0.0 1.0 1 0 0 1 1 1 1 ANTH domain Ribonuc_2-5A PF06479.12 CBY13263.1 - 0.0019 18.4 0.0 0.0048 17.1 0.0 1.7 2 1 0 2 2 2 1 Ribonuclease 2-5A ACT_5 PF13710.6 CBY13264.1 - 0.29 11.0 3.3 0.47 10.3 1.6 2.3 2 0 0 2 2 2 0 ACT domain DUF1664 PF07889.12 CBY13264.1 - 3.7 7.6 6.7 1.6 8.8 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Myosin_head PF00063.21 CBY13267.1 - 3.3e-267 888.1 0.0 3.3e-267 888.1 0.0 2.6 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY13267.1 - 6.7e-139 464.6 263.6 8.8e-139 464.2 263.6 1.0 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.9 CBY13267.1 - 0.0035 17.4 29.7 0.0035 17.4 29.7 11.4 2 2 9 11 11 11 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.6 CBY13267.1 - 0.076 13.3 0.0 0.076 13.3 0.0 4.9 4 1 1 5 5 5 0 AAA domain CcmF_C PF16327.5 CBY13267.1 - 0.12 11.6 1.4 0.33 10.2 1.4 1.7 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal AAA_16 PF13191.6 CBY13267.1 - 1.7 9.0 0.0 1.7 9.0 0.0 5.1 5 1 0 5 5 5 0 AAA ATPase domain ADIP PF11559.8 CBY13268.1 - 0.0021 18.2 13.3 0.0021 18.2 13.3 3.2 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding KLRAQ PF10205.9 CBY13268.1 - 0.0034 17.6 8.4 0.0034 17.6 8.4 2.5 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 CBY13268.1 - 0.07 13.5 17.2 0.66 10.4 0.8 4.2 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) ALMT PF11744.8 CBY13268.1 - 0.28 10.0 13.4 0.36 9.6 13.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter GAS PF13851.6 CBY13268.1 - 0.66 9.3 32.2 1.3 8.4 18.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 CBY13268.1 - 0.72 9.6 19.1 0.18 11.6 11.0 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 YabA PF06156.13 CBY13268.1 - 2 9.1 26.1 0.11 13.1 5.8 3.2 1 1 1 3 3 3 0 Initiation control protein YabA Glutaredoxin2_C PF04399.13 CBY13268.1 - 2.5 7.9 7.2 0.45 10.4 0.7 2.6 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain Jnk-SapK_ap_N PF09744.9 CBY13268.1 - 4.5 7.5 36.5 0.7 10.1 8.2 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 CBY13268.1 - 8 6.9 27.7 6.2 7.2 8.3 3.2 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2203 PF09969.9 CBY13268.1 - 8.2 7.2 18.9 0.11 13.3 5.5 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 CBY13268.1 - 9.2 6.3 17.1 6.3 6.9 4.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.32 CBY13270.1 - 3.7e-24 84.5 1.9 2e-06 28.4 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Katanin_con80 PF13925.6 CBY13270.1 - 2.9e-15 56.7 1.0 5.7e-15 55.7 1.0 1.5 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 CBY13270.1 - 9.3e-12 45.1 0.1 0.0037 17.5 0.0 4.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY13270.1 - 0.018 14.0 0.1 0.35 9.8 0.0 2.8 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY13270.1 - 0.019 13.6 0.4 2.8 6.5 0.0 3.1 1 1 2 4 4 4 0 Nucleoporin Nup120/160 PAN_3 PF08277.12 CBY13270.1 - 0.17 11.7 0.0 0.5 10.2 0.0 1.8 1 0 0 1 1 1 0 PAN-like domain Tmemb_18A PF09771.9 CBY13271.1 - 2e-35 121.7 0.1 2.2e-35 121.6 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 Spo7 PF03907.13 CBY13271.1 - 0.00053 19.5 0.2 0.00066 19.2 0.2 1.1 1 0 0 1 1 1 1 Spo7-like protein DUF4131 PF13567.6 CBY13271.1 - 0.18 11.4 3.1 0.24 11.0 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Requiem_N PF14051.6 CBY13272.1 - 1.2 9.4 5.0 2.2 8.5 0.2 2.4 2 1 0 2 2 2 0 N-terminal domain of DPF2/REQ. Arm PF00514.23 CBY13273.1 - 4.5e-27 93.2 15.0 1.4e-07 31.3 0.6 8.4 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CBY13273.1 - 1.6e-05 24.9 5.4 0.0015 18.5 0.2 3.8 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 CBY13273.1 - 0.00054 20.3 0.1 7.8 7.0 0.0 3.7 2 2 0 3 3 3 2 HEAT repeats V-ATPase_H_N PF03224.14 CBY13273.1 - 0.0094 15.3 9.9 0.058 12.7 6.1 2.7 2 1 0 2 2 2 1 V-ATPase subunit H DUF3636 PF12331.8 CBY13273.1 - 0.033 14.0 0.1 0.28 11.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3636) GpcrRhopsn4 PF10192.9 CBY13273.1 - 0.034 13.5 1.3 0.058 12.8 1.3 1.3 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain DUF3361 PF11841.8 CBY13273.1 - 0.23 11.4 14.5 1 9.3 0.8 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 CBY13273.1 - 0.34 11.5 3.6 3.4 8.3 0.1 3.8 2 1 1 3 3 3 0 HEAT-like repeat RasGEF_N_2 PF14663.6 CBY13273.1 - 1 9.8 6.0 5.3 7.5 0.2 3.6 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CBFD_NFYB_HMF PF00808.23 CBY13274.1 - 6.4e-22 77.6 1.4 9.4e-22 77.1 0.8 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY13274.1 - 6.4e-15 55.7 2.4 1.1e-14 54.9 2.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 CBY13274.1 - 0.0091 16.3 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.17 CBY13274.1 - 0.29 11.3 0.2 0.29 11.3 0.2 1.9 3 0 0 3 3 3 0 TATA box binding protein associated factor (TAF) Pkinase PF00069.25 CBY13275.1 - 8.1e-53 179.5 0.0 9.8e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13275.1 - 3e-28 98.8 0.0 3.3e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY13275.1 - 0.0014 18.0 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY13275.1 - 0.007 15.7 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBY13275.1 - 0.0096 15.9 0.0 0.039 13.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CBY13275.1 - 0.016 14.8 0.3 0.064 12.9 0.2 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 WW_1 PF18507.1 CBY13275.1 - 0.052 13.2 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 WW domain Pkinase PF00069.25 CBY13276.1 - 2.6e-75 253.2 0.0 3.9e-75 252.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13276.1 - 6.6e-37 127.2 0.0 1e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CaMKII_AD PF08332.10 CBY13276.1 - 1.4e-16 60.8 0.4 3.3e-16 59.6 0.4 1.6 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 CBY13276.1 - 7.6e-07 29.5 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Kinase-like PF14531.6 CBY13276.1 - 1e-06 28.3 0.1 0.0007 19.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SnoaL_3 PF13474.6 CBY13276.1 - 3.1e-06 27.4 0.1 7.1e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 SnoaL-like domain Kdo PF06293.14 CBY13276.1 - 0.00065 19.1 0.4 0.0052 16.2 0.0 2.2 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY13276.1 - 0.0031 17.5 0.0 1.1 9.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family TMEM214 PF10151.9 CBY13276.1 - 0.011 14.3 4.2 0.018 13.6 4.2 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF1640 PF07798.11 CBY13276.1 - 0.31 11.1 8.4 0.34 10.9 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) RRM_1 PF00076.22 CBY13277.1 - 3.9e-14 52.2 0.0 6.8e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EGF_CA PF07645.15 CBY13278.1 - 1.1e-11 44.7 63.2 2.8e-06 27.4 1.4 8.2 7 2 0 7 7 7 4 Calcium-binding EGF domain EGF_3 PF12947.7 CBY13278.1 - 2.7e-06 27.5 59.3 0.00073 19.7 5.4 6.9 7 0 0 7 7 7 4 EGF domain cEGF PF12662.7 CBY13278.1 - 0.00044 20.1 21.6 0.022 14.7 0.2 6.0 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.27 CBY13278.1 - 0.0023 18.2 5.0 0.0023 18.2 5.0 7.0 7 1 0 7 7 7 3 EGF-like domain WD40 PF00400.32 CBY13280.1 - 1.4e-06 28.9 3.9 3.7 8.6 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat FIVAR PF07554.13 CBY13280.1 - 0.073 13.8 0.1 1.4 9.8 0.0 2.5 2 0 0 2 2 2 0 FIVAR domain RCC1_2 PF13540.6 CBY13280.1 - 0.11 12.4 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Snf7 PF03357.21 CBY13281.1 - 1e-17 64.3 13.8 1.6e-17 63.7 13.0 1.7 2 0 0 2 2 2 1 Snf7 DUF948 PF06103.11 CBY13281.1 - 0.18 12.1 1.0 0.83 10.0 0.4 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Halo_GVPC PF05465.13 CBY13281.1 - 0.29 11.4 4.4 0.15 12.3 1.0 2.4 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat IATP PF04568.12 CBY13281.1 - 2.3 8.7 4.8 3.4 8.1 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP DUF719 PF05334.13 CBY13281.1 - 3.6 7.7 15.7 84 3.3 15.7 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF719) DUF647 PF04884.14 CBY13282.1 - 2.8e-27 95.9 0.0 3.1e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis ArfGap PF01412.18 CBY13283.1 - 5.3e-41 139.4 4.4 9.3e-41 138.6 4.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-CCHC PF00098.23 CBY13284.1 - 6.4e-05 22.8 3.4 0.00013 21.9 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Sin_N PF04801.13 CBY13284.1 - 0.0022 17.3 21.2 0.0043 16.3 21.2 1.5 1 0 0 1 1 1 1 Sin-like protein conserved region SprA-related PF12118.8 CBY13284.1 - 4.4 6.3 37.4 7.8 5.5 37.4 1.3 1 0 0 1 1 1 0 SprA-related family GREB1 PF15782.5 CBY13284.1 - 8.7 3.3 24.2 12 2.9 24.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Proteasome PF00227.26 CBY13285.1 - 5.4e-29 101.0 0.0 6.9e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBY13285.1 - 1.8e-13 49.9 0.0 2.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Piwi PF02171.17 CBY13287.1 - 1.2e-24 87.1 0.0 2.3e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CBY13287.1 - 2.9e-09 36.8 0.2 6.3e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 CBY13287.1 - 0.00048 20.4 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ASH PF15780.5 CBY13288.1 - 4.6e-06 26.8 0.6 0.0015 18.7 0.0 3.4 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin NIBRIN_BRCT_II PF16508.5 CBY13288.1 - 0.14 12.5 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein Ras PF00071.22 CBY13289.1 - 4.6e-45 153.1 0.2 6.6e-45 152.6 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY13289.1 - 1.1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY13289.1 - 1.4e-09 37.7 0.0 1.6e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY13289.1 - 4.3e-05 23.1 0.0 5.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY13289.1 - 0.0051 16.7 0.0 2.4 8.0 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase zf-C2H2 PF00096.26 CBY13289.1 - 0.01 16.3 0.3 0.024 15.1 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type MMR_HSR1_Xtn PF16897.5 CBY13289.1 - 0.03 14.4 0.7 0.091 12.8 0.7 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 CBY13289.1 - 0.15 12.4 0.0 0.27 11.5 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 CBY13289.1 - 0.21 11.9 0.1 0.46 10.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain DnaJ PF00226.31 CBY13290.1 - 3e-22 78.5 2.5 3e-22 78.5 2.5 2.2 2 0 0 2 2 2 1 DnaJ domain DnaJ_C PF01556.18 CBY13290.1 - 2.1e-17 63.6 0.0 4.6e-17 62.5 0.0 1.5 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBY13290.1 - 2.2e-09 37.5 13.9 4.3e-09 36.6 13.9 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBY13290.1 - 8.3e-07 28.9 9.0 9.6e-05 22.3 0.8 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein RHINO PF15319.6 CBY13290.1 - 0.053 13.6 0.1 0.091 12.8 0.1 1.3 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein DHC_N1 PF08385.12 CBY13290.1 - 0.056 12.1 0.2 0.082 11.5 0.2 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DUF1307 PF06998.11 CBY13290.1 - 0.085 12.9 0.6 0.16 12.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) DUF3365 PF11845.8 CBY13290.1 - 0.44 10.9 2.3 0.72 10.2 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) HypA PF01155.19 CBY13290.1 - 0.54 10.3 8.4 0.82 9.7 0.5 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 CBY13290.1 - 1.3 8.4 11.1 0.53 9.7 4.3 2.9 1 1 2 3 3 3 0 Transcription factor zinc-finger zf_CopZ PF18423.1 CBY13290.1 - 3.6 7.6 10.9 2.7 8.0 0.1 3.8 4 0 0 4 4 4 0 Zinc binding domain WD40 PF00400.32 CBY13291.1 - 0.096 13.6 0.2 0.61 11.1 0.6 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Chromo PF00385.24 CBY13292.1 - 2.7e-12 46.4 5.0 5.4e-12 45.4 5.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2625 PF10946.8 CBY13292.1 - 0.027 13.5 0.6 0.044 12.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2625 LRR_4 PF12799.7 CBY13293.1 - 0.007 16.8 1.5 0.021 15.3 0.4 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY13293.1 - 0.11 13.2 0.3 1.4 9.8 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich Repeat DUF5111 PF17138.4 CBY13294.1 - 0.0063 16.4 0.3 0.053 13.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5111) Pet20 PF08692.10 CBY13294.1 - 2.7 8.7 7.1 10 6.9 6.5 2.2 1 1 0 1 1 1 0 Mitochondrial protein Pet20 zf-C2H2_4 PF13894.6 CBY13297.1 - 3.1 8.9 9.2 48 5.2 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger PWWP PF00855.17 CBY13299.1 - 2.1e-08 34.4 0.7 7.6e-08 32.7 0.1 2.1 2 0 0 2 2 2 1 PWWP domain PWWP PF00855.17 CBY13300.1 - 2.1e-16 60.1 0.9 6.2e-16 58.6 0.9 1.8 1 0 0 1 1 1 1 PWWP domain Kelch_5 PF13854.6 CBY13301.1 - 1.5e-17 63.2 7.4 0.00024 21.0 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CBY13301.1 - 1.8e-12 47.1 3.5 0.003 17.5 0.0 6.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY13301.1 - 2.9e-08 33.7 1.9 5.8 7.4 0.1 6.7 6 0 0 6 6 6 2 Kelch motif PSI PF01437.25 CBY13301.1 - 4.1e-08 33.6 32.5 4.3e-06 27.2 9.5 7.0 6 1 0 6 6 6 2 Plexin repeat Kelch_2 PF07646.15 CBY13301.1 - 6.3e-08 32.3 8.4 0.069 13.2 0.0 6.4 7 0 0 7 7 7 2 Kelch motif Kelch_3 PF13415.6 CBY13301.1 - 0.00018 21.7 4.3 2.9 8.3 0.1 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY13301.1 - 0.0005 19.6 0.6 3.5 7.3 0.0 5.5 6 0 0 6 6 6 1 Kelch motif Laminin_EGF PF00053.24 CBY13301.1 - 0.0011 19.1 43.3 0.0019 18.3 16.7 5.2 5 1 1 6 6 6 2 Laminin EGF domain Nup35_RRM_2 PF14605.6 CBY13302.1 - 6.5e-12 45.3 0.1 5.5e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 CBY13302.1 - 5.1e-09 36.3 1.9 7.3e-09 35.8 0.2 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 CBY13302.1 - 1.2e-07 31.4 0.2 0.00012 21.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CBY13302.1 - 5e-05 23.1 3.0 0.0001 22.1 3.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY13302.1 - 0.0018 18.2 2.3 0.0032 17.5 2.3 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM PF05172.13 CBY13302.1 - 0.0029 17.5 0.3 0.1 12.5 0.0 2.9 2 2 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY13302.1 - 0.0077 16.3 4.2 0.54 10.3 0.4 3.4 3 0 0 3 3 3 1 RNA binding motif RL PF17797.1 CBY13302.1 - 0.011 15.7 0.1 11 6.0 0.0 3.1 3 0 0 3 3 3 0 RL domain DUF1866 PF08952.11 CBY13302.1 - 0.013 15.4 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_5 PF13893.6 CBY13302.1 - 0.019 14.6 0.0 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 CBY13302.1 - 0.51 10.9 3.0 2.1 8.9 0.1 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger tRNA-synt_2 PF00152.20 CBY13303.1 - 1.8e-75 253.9 0.1 2.9e-75 253.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 CBY13303.1 - 1e-19 70.4 1.2 1e-19 70.4 1.2 2.3 1 1 2 3 3 3 1 WHEP-TRS domain tRNA_anti-codon PF01336.25 CBY13303.1 - 0.00026 20.9 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBY13303.1 - 0.0017 17.9 0.5 0.97 8.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NARP1 PF12569.8 CBY13303.1 - 2.1 7.2 17.7 3.6 6.4 17.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NUP50 PF08911.11 CBY13304.1 - 6.9e-17 61.9 4.8 6.9e-17 61.9 4.8 3.5 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 CBY13304.1 - 1.2e-07 32.1 0.1 1.2e-06 28.7 0.0 2.4 2 1 0 2 2 2 1 RanBP1 domain nsp9 PF08710.10 CBY13304.1 - 0.16 12.4 0.1 0.46 10.9 0.1 1.7 1 0 0 1 1 1 0 nsp9 replicase WD40 PF00400.32 CBY13305.1 - 4e-38 128.7 11.7 0.00037 21.2 0.0 11.3 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY13305.1 - 1.2e-13 51.1 0.5 0.0079 16.5 0.0 8.0 4 3 5 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY13305.1 - 8.6e-05 22.0 2.2 0.035 13.4 0.0 3.5 3 1 1 4 4 4 2 WD40-like domain eIF2A PF08662.11 CBY13305.1 - 0.00011 22.2 0.0 0.021 14.7 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 CBY13305.1 - 0.001 19.5 3.2 8.6 7.0 0.0 5.8 7 0 0 7 7 7 1 PQQ-like domain PQQ_2 PF13360.6 CBY13305.1 - 0.0053 16.4 0.0 0.16 11.5 0.0 2.8 2 1 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 CBY13305.1 - 0.078 11.9 0.0 5.1 6.0 0.0 3.4 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Y_phosphatase PF00102.27 CBY13306.1 - 3.8e-70 236.1 0.4 7.8e-70 235.1 0.1 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase fn3 PF00041.21 CBY13306.1 - 3.8e-16 59.2 8.0 3e-06 27.5 0.1 5.6 5 0 0 5 5 5 4 Fibronectin type III domain DUF4448 PF14610.6 CBY13306.1 - 5.9e-05 22.9 0.1 0.00016 21.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DSPc PF00782.20 CBY13306.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SKG6 PF08693.10 CBY13306.1 - 0.0016 17.8 6.5 0.0038 16.6 6.5 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 CBY13306.1 - 0.0057 15.5 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 Amnionless DUF3377 PF11857.8 CBY13306.1 - 0.033 14.1 0.8 0.074 13.0 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Y_phosphatase3 PF13350.6 CBY13306.1 - 0.091 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family TMEM154 PF15102.6 CBY13306.1 - 0.093 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family PTPlike_phytase PF14566.6 CBY13306.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Insulin_TMD PF17870.1 CBY13306.1 - 0.17 12.0 4.5 0.072 13.2 1.7 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Stevor PF17410.2 CBY13306.1 - 0.21 11.1 0.2 0.38 10.3 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4519 PF15012.6 CBY13306.1 - 6.2 7.1 7.7 0.49 10.6 2.7 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4519) bZIP_1 PF00170.21 CBY13307.1 - 2.6e-18 65.8 13.3 4e-18 65.3 13.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY13307.1 - 8.7e-08 32.1 12.2 1.5e-07 31.3 12.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY13307.1 - 0.0002 21.8 3.4 0.00028 21.3 3.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Rh5 PF18515.1 CBY13307.1 - 0.012 15.0 0.9 0.015 14.6 0.9 1.1 1 0 0 1 1 1 0 Rh5 coiled-coil domain zf-C3HC4_3 PF13920.6 CBY13308.1 - 0.0041 17.0 10.5 0.0041 17.0 10.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C4_ClpX PF06689.13 CBY13308.1 - 0.0045 16.9 3.8 0.0045 16.9 3.8 2.4 2 0 0 2 2 1 1 ClpX C4-type zinc finger zf-RING_2 PF13639.6 CBY13308.1 - 0.014 15.7 12.6 0.014 15.7 12.6 2.0 2 0 0 2 2 2 0 Ring finger domain zf-dskA_traR PF01258.17 CBY13308.1 - 0.051 13.5 3.6 0.22 11.5 0.9 2.5 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DUF1938 PF09153.10 CBY13308.1 - 0.13 12.3 0.4 0.23 11.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) MDM10 PF12519.8 CBY13308.1 - 0.17 10.7 3.9 0.21 10.4 3.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Gin PF10764.9 CBY13308.1 - 1.1 9.3 16.3 0.48 10.4 3.3 2.7 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zf_UBZ PF18439.1 CBY13308.1 - 2.4 7.8 9.2 0.11 12.1 2.7 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 CBY13308.1 - 3.8 7.7 14.6 25 5.1 14.6 2.3 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 CBY13308.1 - 6 6.8 21.0 0.22 11.4 13.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DnaG_DnaB_bind PF08278.11 CBY13308.1 - 7 7.3 8.6 0.17 12.5 1.4 2.0 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding zf-RING_5 PF14634.6 CBY13308.1 - 7.6 6.6 21.0 0.37 10.8 13.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Sema PF01403.19 CBY13310.1 - 3.7e-40 138.0 0.0 5.5e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Sema domain Podoplanin PF05808.11 CBY13310.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Podoplanin PSI PF01437.25 CBY13310.1 - 0.16 12.5 5.3 0.36 11.4 5.3 1.6 1 0 0 1 1 1 0 Plexin repeat FAM104 PF15434.6 CBY13310.1 - 9.4 6.8 8.2 0.85 10.2 1.9 2.3 2 0 0 2 2 2 0 Family 104 Galactosyl_T PF01762.21 CBY13311.1 - 2.8e-23 82.7 0.4 3.7e-23 82.4 0.4 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF5487 PF17589.2 CBY13311.1 - 0.087 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5487) EGF PF00008.27 CBY13313.1 - 9e-16 57.9 80.4 1.6e-05 25.1 6.4 6.4 6 0 0 6 6 6 5 EGF-like domain VWA_2 PF13519.6 CBY13313.1 - 2.3e-12 47.5 0.1 5.9e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CBY13313.1 - 4e-11 43.5 0.1 6.8e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_2 PF07974.13 CBY13313.1 - 0.00015 22.1 90.9 0.012 16.0 12.8 6.7 6 0 0 6 6 6 4 EGF-like domain VWA_CoxE PF05762.14 CBY13313.1 - 0.19 11.1 0.5 0.65 9.3 0.1 2.0 2 1 0 2 2 2 0 VWA domain containing CoxE-like protein hEGF PF12661.7 CBY13313.1 - 0.54 11.0 71.2 0.066 13.9 4.1 7.3 6 0 0 6 6 6 0 Human growth factor-like EGF Orn_Arg_deC_N PF02784.16 CBY13314.1 - 1.1e-35 123.2 0.0 1.7e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CBY13314.1 - 2.5e-14 53.3 0.0 4.2e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 CBY13314.1 - 0.017 14.7 0.0 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 Alanine racemase, N-terminal domain TPR_14 PF13428.6 CBY13315.1 - 0.0062 17.3 2.3 5.5 8.1 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat FISNA PF14484.6 CBY13315.1 - 0.18 12.1 1.3 0.49 10.7 1.3 1.7 1 0 0 1 1 1 0 Fish-specific NACHT associated domain Lzipper-MIP1 PF14389.6 CBY13318.1 - 0.42 10.9 3.9 1 9.7 0.6 2.9 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Baculo_PEP_C PF04513.12 CBY13318.1 - 0.46 10.5 3.6 23 5.0 1.6 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nbas_N PF15492.6 CBY13320.1 - 3.5e-16 59.4 0.1 1.6e-15 57.2 0.1 2.1 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.25 CBY13321.1 - 2.2e-15 56.8 0.0 1.3e-14 54.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13321.1 - 1.4e-11 44.2 0.0 4.4e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase BPL_LplA_LipB PF03099.19 CBY13322.1 - 0.00027 20.8 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF4709 PF15821.5 CBY13323.1 - 4.6e-31 107.4 2.3 4.6e-31 107.4 2.3 4.3 3 1 1 4 4 4 1 Domain of unknown function (DUF4709) MtrG PF04210.13 CBY13323.1 - 0.14 12.0 4.6 0.78 9.6 0.0 3.7 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G NIL PF09383.10 CBY13323.1 - 0.23 11.3 0.9 30 4.6 0.0 3.2 3 0 0 3 3 3 0 NIL domain DUF842 PF05811.13 CBY13323.1 - 2.4 7.8 15.9 1.4 8.6 9.5 3.5 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) DUF4187 PF13821.6 CBY13324.1 - 3.6e-15 55.5 3.4 3.6e-15 55.5 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CBY13324.1 - 8.4e-12 44.8 5.2 1.5e-11 44.0 5.2 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBY13324.1 - 0.0072 16.4 2.9 0.021 14.9 2.9 1.8 1 0 0 1 1 1 1 G-patch domain DUF1604 PF07713.13 CBY13324.1 - 0.054 13.3 4.5 0.28 11.0 0.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1604) zf-C2H2_jaz PF12171.8 CBY13324.1 - 2.8 8.3 7.0 0.4 11.0 2.2 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LRR_6 PF13516.6 CBY13325.1 - 1e-09 37.7 25.1 0.025 14.6 0.1 7.3 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 CBY13325.1 - 1.1e-08 35.2 15.3 0.0039 17.6 2.1 6.1 2 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY13325.1 - 0.0073 16.7 13.8 48 5.1 0.4 6.7 6 1 0 6 6 6 0 Leucine Rich Repeat G6B PF15096.6 CBY13325.1 - 0.02 14.7 0.2 0.079 12.7 0.0 2.0 2 0 0 2 2 2 0 G6B family LRR_9 PF14580.6 CBY13325.1 - 0.044 13.3 1.4 0.09 12.3 1.4 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 CBY13325.1 - 5.9 6.7 20.6 0.61 9.9 0.7 5.8 5 2 0 5 5 5 0 Leucine rich repeat MecA_N PF05223.11 CBY13326.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain Apyrase PF06079.11 CBY13327.1 - 1.3e-117 392.2 0.2 1.7e-117 391.9 0.2 1.0 1 0 0 1 1 1 1 Apyrase F-box-like PF12937.7 CBY13328.1 - 0.054 13.4 0.7 0.13 12.2 0.7 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 CBY13328.1 - 0.83 9.6 4.8 0.27 11.2 0.6 2.4 2 0 0 2 2 2 0 F-box domain DEAD PF00270.29 CBY13329.1 - 3.6e-40 137.6 0.1 7.4e-40 136.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY13329.1 - 5.5e-31 107.2 0.0 6.1e-26 91.0 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CBY13329.1 - 2.8e-07 30.7 5.3 3.5e-07 30.4 0.0 2.6 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBY13329.1 - 0.004 17.4 0.5 0.028 14.7 0.5 2.3 1 1 0 1 1 1 1 AAA domain Rft-1 PF04506.13 CBY13330.1 - 1e-69 235.7 19.9 4.4e-69 233.6 19.9 1.9 1 1 0 1 1 1 1 Rft protein SHQ1 PF04925.15 CBY13332.1 - 1.7e-43 148.2 0.1 2.5e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein DnaJ PF00226.31 CBY13333.1 - 1.6e-24 85.8 2.8 2.5e-24 85.2 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain Prominin PF05478.11 CBY13333.1 - 0.057 11.4 8.9 0.071 11.1 8.9 1.1 1 0 0 1 1 1 0 Prominin U79_P34 PF03064.16 CBY13333.1 - 0.52 9.6 3.9 0.66 9.3 3.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Renin_r PF07850.14 CBY13334.1 - 0.0076 16.8 0.0 0.018 15.6 0.0 1.6 1 1 0 1 1 1 1 Renin receptor-like protein Ephrin_rec_like PF07699.13 CBY13335.1 - 3.1e-07 30.1 2.4 3.1e-07 30.1 2.4 2.6 1 1 1 2 2 2 1 Putative ephrin-receptor like FAM176 PF14851.6 CBY13335.1 - 7.1e-05 22.5 1.2 7.1e-05 22.5 1.2 2.3 1 1 1 2 2 2 1 FAM176 family HYR PF02494.16 CBY13335.1 - 0.00036 20.8 0.0 0.0015 18.8 0.0 2.1 1 0 0 1 1 1 1 HYR domain EphA2_TM PF14575.6 CBY13335.1 - 0.0005 20.9 0.1 0.0012 19.7 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 CBY13335.1 - 0.032 14.5 0.5 0.079 13.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) GAPT PF11770.8 CBY13335.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) AmpE PF17113.5 CBY13335.1 - 0.19 11.1 0.2 0.27 10.5 0.2 1.1 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE DUF1003 PF06210.11 CBY13335.1 - 0.22 11.6 2.3 0.67 10.1 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Syndecan PF01034.20 CBY13335.1 - 0.23 11.4 0.4 0.48 10.4 0.4 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4834 PF16118.5 CBY13335.1 - 0.29 12.1 2.1 1.1 10.2 2.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM51 PF15345.6 CBY13335.1 - 0.32 10.8 9.6 0.12 12.3 3.5 2.4 1 1 1 2 2 2 0 Transmembrane protein 51 SID-1_RNA_chan PF13965.6 CBY13335.1 - 0.89 7.9 3.1 1.7 7.0 3.1 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4446 PF14584.6 CBY13335.1 - 1.2 9.1 4.9 0.22 11.5 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Neur_chan_memb PF02932.16 CBY13335.1 - 2.7 8.0 6.9 2.5 8.1 5.5 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop25 PF09805.9 CBY13335.1 - 4.5 7.8 22.9 9.5 6.7 22.9 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) zf-C2H2_4 PF13894.6 CBY13336.1 - 0.15 13.0 2.2 0.36 11.8 2.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger COX16 PF14138.6 CBY13336.1 - 3.3 8.3 6.4 15 6.2 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 LNS2 PF08235.13 CBY13339.1 - 6.8e-61 205.6 2.9 1.7e-59 201.1 2.9 2.6 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_mid PF16876.5 CBY13339.1 - 1.4e-16 60.5 0.0 9.3e-16 57.8 0.0 2.4 2 1 1 3 3 3 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Kelch_5 PF13854.6 CBY13340.1 - 0.027 14.5 0.7 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 CBY13340.1 - 0.035 14.1 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Pkinase PF00069.25 CBY13341.1 - 1.8e-09 37.3 0.0 2.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13341.1 - 0.00014 21.2 0.1 0.00023 20.5 0.1 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY13341.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like VWD PF00094.25 CBY13343.1 - 7e-28 97.9 16.0 1.6e-07 31.7 3.5 5.9 4 1 0 4 4 4 4 von Willebrand factor type D domain C8 PF08742.11 CBY13343.1 - 4.8e-09 36.5 23.0 1.8e-05 25.1 2.0 7.4 6 2 2 8 8 8 3 C8 domain TIL PF01826.17 CBY13343.1 - 9.4e-08 32.2 54.5 0.00011 22.3 16.9 9.5 9 0 0 9 9 9 3 Trypsin Inhibitor like cysteine rich domain Lectin_C PF00059.21 CBY13343.1 - 3.6e-07 30.9 2.3 4e-07 30.7 0.1 2.4 2 0 0 2 2 2 1 Lectin C-type domain ShK PF01549.24 CBY13343.1 - 0.0005 20.5 10.8 0.0005 20.5 10.8 6.6 5 1 0 5 5 5 2 ShK domain-like Tme5_EGF_like PF09064.10 CBY13343.1 - 0.0081 16.0 2.6 0.0081 16.0 2.6 6.9 6 0 0 6 6 6 2 Thrombomodulin like fifth domain, EGF-like RVT_1 PF00078.27 CBY13345.1 - 1.8e-12 47.3 0.0 4.1e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CBY13345.1 - 3.5e-06 27.5 0.0 8.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf_CCCH_4 PF18345.1 CBY13345.1 - 2e-05 24.5 3.9 2e-05 24.5 3.9 2.7 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBY13345.1 - 2.5e-05 23.9 3.9 2.5e-05 23.9 3.9 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger Asp_protease_2 PF13650.6 CBY13345.1 - 2.9e-05 24.6 0.0 6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCCH PF00642.24 CBY13345.1 - 7.6e-05 22.5 1.2 7.6e-05 22.5 1.2 2.4 1 1 1 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RVP PF00077.20 CBY13345.1 - 0.0023 18.2 0.1 0.0063 16.8 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CBY13345.1 - 0.012 15.4 0.0 0.31 10.9 0.0 2.8 3 0 0 3 3 3 0 Aspartyl protease Torus PF16131.5 CBY13345.1 - 2.3 9.0 10.4 0.1 13.3 3.4 2.4 3 1 0 3 3 3 0 Torus domain Trypsin PF00089.26 CBY13346.1 - 1.4e-12 47.9 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY13346.1 - 0.0043 17.4 0.0 0.01 16.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Ank_2 PF12796.7 CBY13347.1 - 1.3e-09 38.5 0.0 5.2e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY13347.1 - 2.5e-08 34.0 0.0 2.6e-05 24.4 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY13347.1 - 8.9e-07 29.1 0.0 0.027 14.9 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CBY13347.1 - 5.9e-06 26.7 0.0 0.79 10.4 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY13347.1 - 0.00025 21.3 0.0 8.3 7.3 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeat PT-VENN PF04829.13 CBY13348.1 - 0.071 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Kelch_2 PF07646.15 CBY13349.1 - 0.0035 17.3 1.0 7.5 6.7 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY13349.1 - 0.042 14.2 0.4 1.9 8.9 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Raffinose_syn PF05691.12 CBY13350.1 - 0.00063 17.7 0.0 0.00099 17.0 0.0 1.2 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 WYL_2 PF10902.8 CBY13350.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold Abhydrolase_2 PF02230.16 CBY13351.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PS_Dcarbxylase PF02666.15 CBY13353.1 - 1.2e-49 168.5 0.0 1.7e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Cupin_8 PF13621.6 CBY13354.1 - 5.5e-32 111.5 0.0 7.5e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY13354.1 - 2e-05 24.2 0.0 9.4e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 CBY13354.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Cupin JmjC PF02373.22 CBY13354.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Baculo_PEP_C PF04513.12 CBY13355.1 - 1 9.4 8.7 0.13 12.3 3.1 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Trypsin PF00089.26 CBY13356.1 - 7e-143 474.0 0.0 2.8e-52 177.7 0.0 3.2 3 0 0 3 3 3 3 Trypsin DUF1986 PF09342.11 CBY13356.1 - 5.1e-22 78.4 0.0 1.6e-07 31.7 0.0 3.7 3 0 0 3 3 3 3 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY13356.1 - 5.2e-13 50.2 0.0 0.00094 20.1 0.0 3.5 3 0 0 3 3 3 3 Trypsin-like peptidase domain DUF316 PF03761.15 CBY13356.1 - 1.2e-11 44.7 0.0 0.022 14.3 0.0 4.5 5 0 0 5 5 5 3 Chymotrypsin family Peptidase-S1 Frtz PF11768.8 CBY13356.1 - 0.00016 20.1 0.0 1 7.6 0.0 3.0 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PBECR3 PF18812.1 CBY13356.1 - 0.45 10.5 6.5 4.2 7.4 0.3 3.3 3 0 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 PS_Dcarbxylase PF02666.15 CBY13358.1 - 6.1e-43 146.7 0.0 7.3e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2101 PF09874.9 CBY13359.1 - 0.056 13.1 2.4 0.062 13.0 2.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Kelch_2 PF07646.15 CBY13360.1 - 0.001 19.0 1.2 0.4 10.7 0.0 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CBY13360.1 - 0.027 14.5 0.1 0.58 10.2 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY13360.1 - 0.028 14.7 4.4 0.76 10.2 0.1 3.7 2 1 1 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY13360.1 - 0.036 14.1 4.4 1 9.4 0.0 3.1 3 0 0 3 3 3 0 Kelch motif FXa_inhibition PF14670.6 CBY13361.1 - 0.00013 22.2 8.3 0.00044 20.5 8.3 2.0 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Glyco_hydro_9 PF00759.19 CBY13362.1 - 7.3e-119 397.9 1.0 9.3e-119 397.5 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Syntaphilin PF15290.6 CBY13362.1 - 0.099 12.3 6.9 0.17 11.5 6.9 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Sporozoite_P67 PF05642.11 CBY13362.1 - 0.11 10.5 2.3 0.14 10.3 2.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nnf1 PF03980.14 CBY13363.1 - 0.097 13.1 0.1 0.1 13.0 0.1 1.3 1 1 0 1 1 1 0 Nnf1 COesterase PF00135.28 CBY13364.1 - 5.2e-53 180.7 0.3 1.5e-52 179.1 0.1 1.7 1 1 1 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY13364.1 - 4e-06 26.8 0.3 8e-05 22.6 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ig_3 PF13927.6 CBY13365.1 - 8.7e-30 103.2 3.4 9e-10 39.0 0.1 5.8 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 CBY13365.1 - 2.7e-29 101.1 3.7 1.1e-11 44.6 0.1 4.8 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY13365.1 - 7.3e-22 77.5 3.3 9.1e-13 48.4 0.1 5.4 5 1 0 5 5 5 2 Immunoglobulin domain ig PF00047.25 CBY13365.1 - 3e-20 72.2 3.8 1.4e-06 28.4 0.1 4.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CBY13365.1 - 2.2e-18 66.4 2.0 6.2e-12 45.7 0.1 4.9 5 1 1 6 6 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY13365.1 - 5.9e-09 35.9 3.9 1.4e-05 25.1 0.0 4.5 5 0 0 5 5 4 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 CBY13365.1 - 1.9e-06 28.2 3.6 0.00039 20.8 0.0 4.7 4 1 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CBY13365.1 - 3.7e-06 27.1 0.4 0.011 15.9 0.0 3.9 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 CBY13365.1 - 0.0012 18.3 0.0 0.0095 15.5 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain MG2 PF01835.19 CBY13365.1 - 0.0027 18.1 0.5 0.5 10.8 0.0 2.5 2 0 0 2 2 2 1 MG2 domain C2-set PF05790.15 CBY13365.1 - 0.005 17.0 0.1 0.38 11.0 0.1 2.8 2 0 0 2 2 2 1 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 CBY13365.1 - 0.0068 16.4 1.8 0.49 10.4 0.0 3.2 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Izumo-Ig PF16706.5 CBY13365.1 - 0.0072 16.4 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 CBY13365.1 - 0.011 16.1 5.3 1.4 9.4 0.0 5.2 6 1 0 6 6 6 0 Immunoglobulin C1-set domain Scramblase PF03803.15 CBY13366.1 - 4.3e-67 225.7 0.0 7.1e-67 224.9 0.0 1.4 1 0 0 1 1 1 1 Scramblase P22_Cro PF14549.6 CBY13366.1 - 0.072 13.0 0.4 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro SSF PF00474.17 CBY13367.1 - 5e-35 121.1 29.2 6.5e-35 120.8 29.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family wnt PF00110.19 CBY13368.1 - 4.8e-51 174.2 26.2 6e-51 173.9 26.2 1.1 1 0 0 1 1 1 1 wnt family DTHCT PF08070.11 CBY13368.1 - 0.055 14.2 5.2 0.92 10.3 2.2 2.3 2 0 0 2 2 2 0 DTHCT (NUC029) region RecR PF02132.15 CBY13369.1 - 1.7 8.3 6.9 2.1 8.0 0.3 2.3 2 0 0 2 2 2 0 RecR protein ANAPC4_WD40 PF12894.7 CBY13370.1 - 1.4e-05 25.3 0.3 0.15 12.4 0.1 4.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY13370.1 - 0.0013 19.5 13.1 0.71 10.8 1.4 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ETF_QO PF05187.13 CBY13370.1 - 0.084 13.0 0.0 0.88 9.7 0.0 2.6 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Hydin_ADK PF17213.3 CBY13370.1 - 5.8 7.1 5.9 10 6.3 5.9 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Gla PF00594.20 CBY13371.1 - 1.2e-11 44.6 1.2 1.9e-11 44.0 1.2 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain SNF2_N PF00176.23 CBY13372.1 - 4.1e-48 163.9 0.1 8.4e-48 162.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY13372.1 - 1.6e-12 47.7 0.0 6.3e-12 45.8 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ADD_ATRX PF17981.1 CBY13372.1 - 1.1e-09 38.0 0.1 3e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 Cysteine Rich ADD domain zf-4CXXC_R1 PF10497.9 CBY13372.1 - 0.16 12.2 7.1 0.44 10.8 7.1 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD PF00628.29 CBY13372.1 - 4.6 7.2 20.5 2.5 8.1 13.8 2.6 2 0 0 2 2 2 0 PHD-finger Streptin-Immun PF11083.8 CBY13373.1 - 0.27 11.6 9.7 0.13 12.7 1.8 3.9 3 1 1 4 4 4 0 Lantibiotic streptin immunity protein p25-alpha PF05517.12 CBY13373.1 - 0.51 10.5 0.0 0.51 10.5 0.0 2.5 2 1 0 2 2 2 0 p25-alpha zf-MYND PF01753.18 CBY13373.1 - 0.78 9.9 4.8 1.5 8.9 4.8 1.5 1 0 0 1 1 1 0 MYND finger PDCD2_C PF04194.13 CBY13373.1 - 8.6 6.4 9.9 0.17 11.9 1.9 2.3 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain LRR_8 PF13855.6 CBY13374.1 - 1.5e-21 75.9 29.2 5.9e-07 29.2 5.3 5.7 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 CBY13374.1 - 3.1e-14 52.9 34.8 0.00046 20.5 0.5 6.7 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY13374.1 - 0.86 10.4 28.5 10 7.1 0.3 8.2 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 CBY13374.1 - 2.6 8.3 21.6 6 7.2 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich repeat Snf7 PF03357.21 CBY13377.1 - 3.2e-13 49.6 19.3 4.1e-13 49.3 19.3 1.1 1 0 0 1 1 1 1 Snf7 hGDE_central PF14702.6 CBY13377.1 - 0.027 14.1 2.4 0.049 13.3 2.4 1.4 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme GxGYxYP_C PF14323.6 CBY13377.1 - 0.053 13.4 0.7 0.074 12.9 0.7 1.2 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain Snf7 PF03357.21 CBY13378.1 - 8.6e-17 61.3 17.6 1e-16 61.0 17.6 1.1 1 0 0 1 1 1 1 Snf7 GAGA_bind PF06217.12 CBY13378.1 - 0.066 13.5 6.2 0.084 13.1 6.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Methyltrn_RNA_4 PF09936.9 CBY13378.1 - 0.13 12.1 2.1 0.21 11.4 2.1 1.5 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Sulfotransfer_4 PF17784.1 CBY13378.1 - 0.23 11.2 1.8 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 Sulfotransferase domain GrpE PF01025.19 CBY13378.1 - 0.26 11.0 14.8 0.029 14.1 9.9 1.8 2 0 0 2 2 2 0 GrpE CENP-Q PF13094.6 CBY13378.1 - 0.38 11.0 12.6 0.23 11.7 10.6 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit hGDE_central PF14702.6 CBY13378.1 - 0.41 10.3 5.7 0.47 10.1 4.8 1.4 1 1 0 1 1 1 0 Central domain of human glycogen debranching enzyme LMBR1 PF04791.16 CBY13378.1 - 1.4 7.7 6.7 1.8 7.4 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.11 CBY13378.1 - 2.3 8.5 9.3 1.8 8.9 4.6 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_D PF05873.12 CBY13378.1 - 2.9 7.7 11.6 3 7.7 1.3 2.8 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) YlbD_coat PF14071.6 CBY13378.1 - 7.8 6.8 9.0 10 6.4 7.2 2.1 1 1 1 2 2 2 0 Putative coat protein XLF PF09302.11 CBY13379.1 - 0.078 13.1 5.3 0.73 10.0 0.2 2.4 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component FlxA PF14282.6 CBY13379.1 - 0.13 12.3 7.4 0.55 10.3 3.5 2.5 2 0 0 2 2 2 0 FlxA-like protein ABC_tran_CTD PF16326.5 CBY13379.1 - 0.16 12.2 15.8 0.24 11.7 0.8 3.3 2 1 0 3 3 3 0 ABC transporter C-terminal domain Paralemmin PF03285.15 CBY13379.1 - 0.18 11.4 9.0 0.27 10.8 8.1 1.7 1 1 1 2 2 2 0 Paralemmin Golgin_A5 PF09787.9 CBY13379.1 - 0.2 11.1 18.7 1.5 8.2 18.3 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 ALMT PF11744.8 CBY13379.1 - 0.22 10.3 7.0 0.27 10.0 7.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter WDCP PF15390.6 CBY13379.1 - 1.2 7.4 7.2 1.4 7.2 7.2 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family TMF_TATA_bd PF12325.8 CBY13379.1 - 1.9 8.7 18.6 0.7 10.1 4.5 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 CBY13379.1 - 3.4 8.2 10.1 1.5 9.3 3.9 3.1 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ZapA PF05164.13 CBY13379.1 - 5.4 7.5 8.3 19 5.7 8.1 2.0 1 1 0 1 1 1 0 Cell division protein ZapA DUF5595 PF18077.1 CBY13379.1 - 7.8 6.7 8.6 5 7.3 1.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF3450 PF11932.8 CBY13379.1 - 8.9 5.5 15.0 1.6 8.0 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) zf-CHCC PF10276.9 CBY13380.1 - 3.9e-16 58.8 1.6 5.8e-16 58.3 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger domain RimK PF08443.11 CBY13380.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain COX5B PF01215.19 CBY13380.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb RRM_1 PF00076.22 CBY13381.1 - 1.5e-16 59.9 0.0 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY13381.1 - 0.00011 21.8 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CBY13381.1 - 0.0028 17.8 0.0 0.0038 17.4 0.0 1.1 1 0 0 1 1 1 1 RRM-like domain RRM_7 PF16367.5 CBY13381.1 - 0.14 12.3 0.0 0.46 10.6 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif Sec7 PF01369.20 CBY13383.1 - 7.1e-59 198.6 1.1 1.3e-58 197.7 0.3 1.9 2 0 0 2 2 2 1 Sec7 domain IQ_SEC7_PH PF16453.5 CBY13383.1 - 1.5e-49 167.5 0.1 3.9e-49 166.2 0.1 1.7 1 0 0 1 1 1 1 PH domain PH PF00169.29 CBY13383.1 - 0.0036 17.8 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 PH domain IQ PF00612.27 CBY13383.1 - 7 6.7 8.5 0.49 10.3 1.4 2.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif NEMP PF10225.9 CBY13383.1 - 7.4 6.2 6.8 4.8 6.8 3.1 2.2 2 0 0 2 2 2 0 NEMP family Asp-Al_Ex PF06826.12 CBY13384.1 - 0.11 12.3 0.3 0.15 11.9 0.3 1.1 1 0 0 1 1 1 0 Predicted Permease Membrane Region AhpC-TSA_2 PF13911.6 CBY13386.1 - 3.5e-14 52.9 0.1 4.8e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 CBY13386.1 - 1.1e-06 28.5 0.0 2.2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY13386.1 - 0.00098 18.9 0.0 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 Redoxin DUF1805 PF08827.11 CBY13386.1 - 0.089 13.1 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) TetR_C_23 PF17931.1 CBY13387.1 - 0.2 11.8 3.9 0.23 11.6 0.7 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Sugar_tr PF00083.24 CBY13388.1 - 1.4e-10 40.7 8.1 1.9e-10 40.2 8.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY13388.1 - 1.4e-07 30.7 15.5 3.5e-07 29.5 15.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily EGF_2 PF07974.13 CBY13389.1 - 1.1e-12 48.1 96.8 0.00014 22.1 14.7 6.7 6 0 0 6 6 6 6 EGF-like domain EGF PF00008.27 CBY13389.1 - 0.00017 21.8 68.1 0.0038 17.5 5.1 6.7 6 0 0 6 6 6 3 EGF-like domain RHS_repeat PF05593.14 CBY13389.1 - 0.0055 17.2 0.4 6.2 7.4 0.0 4.4 5 0 0 5 5 5 1 RHS Repeat DUF3333 PF11812.8 CBY13389.1 - 0.017 15.4 0.1 0.03 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) SspH PF08141.12 CBY13389.1 - 0.096 12.8 2.3 17 5.6 0.0 3.8 3 0 0 3 3 3 0 Small acid-soluble spore protein H family MORN_2 PF07661.13 CBY13389.1 - 0.33 11.3 2.4 12 6.5 0.0 4.6 5 0 0 5 5 5 0 MORN repeat variant Kazal_2 PF07648.15 CBY13391.1 - 7.5e-14 51.6 7.5 4.9e-11 42.6 1.6 2.6 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CBY13391.1 - 1.3e-05 25.1 5.6 1.3e-05 25.1 5.6 2.5 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Tat PF00539.18 CBY13391.1 - 0.41 10.8 8.2 2.7 8.2 1.0 2.5 1 1 1 2 2 2 0 Transactivating regulatory protein (Tat) Complex1_51K PF01512.17 CBY13392.1 - 5e-49 166.1 0.0 7.1e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CBY13392.1 - 3.6e-26 91.1 0.1 1.5e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CBY13392.1 - 6.8e-07 29.1 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF780 PF05611.11 CBY13392.1 - 0.05 14.4 1.3 0.14 13.0 1.3 1.7 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) DUF3568 PF12092.8 CBY13392.1 - 0.52 10.4 2.1 1 9.5 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) RTP1_C1 PF10363.9 CBY13394.1 - 1.7e-06 28.2 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 CBS PF00571.28 CBY13397.1 - 2.6e-10 40.6 0.0 0.00017 22.0 0.0 2.3 2 0 0 2 2 2 2 CBS domain Voltage_CLC PF00654.20 CBY13398.1 - 6.1e-95 318.5 18.0 8.5e-95 318.0 18.0 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel TAT_signal PF10518.9 CBY13398.1 - 0.84 9.6 8.6 0.054 13.4 2.1 2.5 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence TFR_dimer PF04253.15 CBY13399.1 - 2.1e-29 102.1 0.3 4.5e-29 101.0 0.3 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 CBY13399.1 - 5.2e-11 42.4 0.0 1.4e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 PA domain AAA_lid_10 PF17872.1 CBY13399.1 - 0.02 15.0 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA lid domain Pkinase PF00069.25 CBY13400.1 - 5.6e-64 216.1 0.0 9.8e-64 215.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13400.1 - 3.3e-39 134.7 0.0 7.6e-39 133.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.22 CBY13400.1 - 2.7e-24 84.8 27.8 8.8e-14 51.1 10.2 3.4 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 CBY13400.1 - 1.6e-23 83.0 0.0 3.6e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 CBY13400.1 - 0.00077 20.1 4.0 0.00077 20.1 4.0 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CBY13400.1 - 0.0008 18.4 0.6 0.0014 17.7 0.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY13400.1 - 0.00083 18.7 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C1_2 PF03107.16 CBY13400.1 - 0.0016 18.7 16.3 0.19 12.1 4.2 2.7 2 0 0 2 2 2 2 C1 domain zf-ribbon_3 PF13248.6 CBY13400.1 - 0.16 11.4 1.3 7.4 6.1 0.1 3.5 2 0 0 2 2 2 0 zinc-ribbon domain PHD_2 PF13831.6 CBY13400.1 - 0.41 10.2 16.5 0.6 9.7 0.2 3.2 3 0 0 3 3 3 0 PHD-finger PHD PF00628.29 CBY13400.1 - 1.6 8.7 18.1 2.8 7.9 4.9 3.3 2 1 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 CBY13400.1 - 4.7 7.4 14.7 2.5 8.2 2.7 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger Epimerase PF01370.21 CBY13401.1 - 3.3e-06 26.7 0.0 5.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBY13401.1 - 0.013 14.9 0.1 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ribosomal_L9_C PF03948.14 CBY13401.1 - 0.047 14.1 0.8 0.081 13.4 0.8 1.5 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain FH2 PF02181.23 CBY13404.1 - 1.5e-62 211.9 2.4 1.5e-62 211.9 2.4 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain TRAP_alpha PF03896.16 CBY13405.1 - 0.013 14.7 3.6 0.016 14.5 3.6 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 CBY13405.1 - 0.088 11.1 5.1 0.09 11.1 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 CBY13405.1 - 0.16 12.4 11.1 0.95 9.9 7.4 2.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4637 PF15470.6 CBY13405.1 - 0.18 11.5 3.5 0.23 11.2 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 CBY13405.1 - 0.26 9.4 7.2 0.28 9.3 7.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_38C PF07748.13 CBY13406.1 - 0.00073 19.7 0.1 0.00073 19.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain HSBP1 PF06825.12 CBY13407.1 - 0.015 15.1 3.7 0.036 13.9 0.5 2.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DMP12 PF16779.5 CBY13407.1 - 0.023 14.7 1.6 0.041 13.9 1.6 1.4 1 0 0 1 1 1 0 DNA-mimic protein Spc29 PF17082.5 CBY13407.1 - 2.9 7.7 13.9 0.035 14.0 3.9 2.5 1 1 1 2 2 2 0 Spindle Pole Component 29 KfrA_N PF11740.8 CBY13407.1 - 5.6 7.7 12.0 0.56 10.9 2.9 2.6 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF3450 PF11932.8 CBY13407.1 - 5.7 6.2 16.8 1.7 7.9 11.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3450 PF11932.8 CBY13408.1 - 0.2 11.0 14.8 0.48 9.7 14.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ANAPC2 PF08672.11 CBY13408.1 - 0.22 12.1 3.9 12 6.5 0.1 3.2 2 1 1 3 3 3 0 Anaphase promoting complex (APC) subunit 2 Glyoxalase_2 PF12681.7 CBY13408.1 - 0.3 11.0 4.1 0.66 9.9 3.8 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain QRPTase_C PF01729.19 CBY13408.1 - 0.49 10.1 6.5 0.15 11.8 3.4 1.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain YjbH PF06082.11 CBY13408.1 - 0.53 9.0 5.5 0.59 8.9 5.5 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF1640 PF07798.11 CBY13408.1 - 1.7 8.6 19.7 0.25 11.3 9.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) SHE3 PF17078.5 CBY13408.1 - 4 7.1 23.6 0.63 9.7 18.6 2.2 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 TMPIT PF07851.13 CBY13408.1 - 5.2 6.2 12.1 9.7 5.3 12.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein LPP20 PF02169.16 CBY13408.1 - 7.6 7.0 8.1 19 5.7 7.7 1.9 1 1 0 1 1 1 0 LPP20 lipoprotein STT3 PF02516.14 CBY13409.1 - 2.2e-128 429.3 34.8 1.1e-126 423.6 34.8 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 CBY13409.1 - 0.0095 16.2 9.5 0.0095 16.2 9.5 2.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase OST3_OST6 PF04756.13 CBY13410.1 - 1.1e-49 169.4 0.5 1.3e-49 169.1 0.5 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Trp_oprn_chp PF09534.10 CBY13410.1 - 0.018 14.9 1.8 0.035 13.9 1.8 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TrbC_Ftype PF09673.10 CBY13410.1 - 0.028 14.5 0.0 0.077 13.0 0.0 1.8 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_2 PF13098.6 CBY13410.1 - 0.089 13.2 0.2 0.33 11.4 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CBY13410.1 - 0.69 10.1 3.4 20 5.3 0.3 2.6 2 1 1 3 3 3 0 Thioredoxin Fib_alpha PF08702.10 CBY13411.1 - 0.002 18.3 2.8 0.0053 16.9 2.8 1.7 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family MRF_C1 PF13887.6 CBY13411.1 - 0.013 14.6 0.3 10 5.4 0.0 3.4 3 0 0 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 Laminin_II PF06009.12 CBY13411.1 - 0.019 15.0 9.1 0.22 11.5 7.3 2.7 1 1 1 2 2 2 0 Laminin Domain II HSBP1 PF06825.12 CBY13411.1 - 0.027 14.3 1.3 0.075 12.9 0.2 2.2 2 0 0 2 2 2 0 Heat shock factor binding protein 1 FlaC_arch PF05377.11 CBY13411.1 - 0.06 13.7 8.3 3.3 8.2 2.3 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BAG6 PF12057.8 CBY13411.1 - 0.062 13.0 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 BCL2-associated athanogene 6 BLI1 PF17324.2 CBY13411.1 - 0.14 12.9 3.4 0.25 12.0 0.2 2.5 2 0 0 2 2 2 0 BLOC-1 interactor 1 bZIP_1 PF00170.21 CBY13411.1 - 0.24 11.5 7.1 4.5 7.4 0.5 2.9 2 0 0 2 2 2 0 bZIP transcription factor BLOC1_2 PF10046.9 CBY13411.1 - 0.45 10.9 5.0 1.7 9.0 0.3 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 CBY13411.1 - 0.49 9.9 3.5 1.8 8.1 0.2 2.7 2 0 0 2 2 2 0 fzo-like conserved region CC2-LZ PF16516.5 CBY13411.1 - 0.62 10.5 8.2 7.5 7.0 0.4 2.8 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator zf-ZPR1 PF03367.13 CBY13411.1 - 0.63 9.9 6.0 4.2 7.2 0.5 2.5 1 1 1 2 2 2 0 ZPR1 zinc-finger domain GlcNAc-1_reg PF18440.1 CBY13411.1 - 0.75 10.1 3.4 0.43 10.8 0.2 2.3 3 0 0 3 3 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain Tropomyosin_1 PF12718.7 CBY13411.1 - 0.75 9.9 9.2 9.6 6.3 9.2 2.4 1 1 0 1 1 1 0 Tropomyosin like ZapB PF06005.12 CBY13411.1 - 0.83 10.1 11.3 7.5 7.1 0.2 2.8 2 0 0 2 2 2 0 Cell division protein ZapB DUF4446 PF14584.6 CBY13411.1 - 0.84 9.6 4.0 18 5.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CLZ PF16526.5 CBY13411.1 - 1.8 9.0 10.6 5.4 7.4 0.6 3.0 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 CBY13411.1 - 1.8 9.2 6.4 9.8 6.9 1.9 2.9 2 1 0 2 2 2 0 SlyX XhlA PF10779.9 CBY13411.1 - 6.4 7.1 8.5 4 7.7 0.3 2.7 2 0 0 2 2 2 0 Haemolysin XhlA LIN37 PF15306.6 CBY13411.1 - 6.8 6.9 9.7 1.2 9.4 5.0 2.0 1 1 1 2 2 2 0 LIN37 Beach PF02138.18 CBY13412.1 - 4.3e-14 52.6 0.1 8.6e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CBY13412.1 - 9.8e-12 44.9 0.0 2.3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 CBY13412.1 - 0.14 11.4 9.9 1.6 7.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4704) Beach PF02138.18 CBY13413.1 - 1.4e-83 280.5 0.0 1.8e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 CBY13413.1 - 2.1e-09 37.9 4.3 0.00023 21.9 0.0 4.6 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY13413.1 - 0.0086 16.4 0.0 0.032 14.5 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4160 PF13711.6 CBY13414.1 - 0.048 14.0 0.3 0.22 11.9 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Glyco_hydro_38N PF01074.22 CBY13415.1 - 4e-76 256.1 1.1 6.8e-76 255.4 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CBY13415.1 - 7.2e-22 78.5 0.1 4.7e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CBY13415.1 - 1.4e-19 70.0 0.0 4.5e-19 68.4 0.0 2.0 1 0 0 1 1 1 1 Alpha mannosidase middle domain AARP2CN PF08142.12 CBY13416.1 - 2.8e-31 107.4 0.0 1e-30 105.6 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 CBY13416.1 - 2.1e-05 24.1 2.3 0.0039 16.7 0.0 3.0 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY13416.1 - 0.0017 18.4 2.1 0.0055 16.8 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY13416.1 - 0.0019 18.6 0.0 0.0069 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CBY13416.1 - 0.0058 17.0 0.0 0.79 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 CBY13416.1 - 0.0094 16.2 0.2 0.031 14.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 CBY13416.1 - 0.01 15.9 0.0 0.057 13.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CBY13416.1 - 0.01 16.0 2.0 0.19 12.0 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CBY13416.1 - 0.02 14.1 1.1 0.023 13.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 CBY13416.1 - 0.025 15.1 0.5 0.18 12.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 CBY13416.1 - 0.047 13.5 1.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CBY13416.1 - 0.065 13.1 0.0 0.57 10.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 CBY13416.1 - 0.072 13.2 1.5 0.33 11.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 CBY13416.1 - 0.17 11.6 4.7 0.63 9.7 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase Cyclin_N PF00134.23 CBY13417.1 - 4.2e-36 123.5 0.4 7.8e-36 122.6 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3873 PF12989.7 CBY13417.1 - 0.034 14.5 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) PfkB PF00294.24 CBY13419.1 - 2.8e-60 204.2 0.5 3.4e-60 203.9 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Lectin_C PF00059.21 CBY13420.1 - 4.7e-12 46.6 4.8 2e-08 34.9 0.9 4.1 4 2 1 5 5 5 2 Lectin C-type domain Xlink PF00193.17 CBY13420.1 - 0.0027 18.0 2.1 0.0061 16.9 0.1 2.5 2 0 0 2 2 2 1 Extracellular link domain Nop14 PF04147.12 CBY13420.1 - 0.085 11.1 5.3 0.12 10.6 5.3 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 CBY13420.1 - 0.11 12.6 5.8 0.2 11.7 5.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 CBY13420.1 - 0.42 10.3 5.5 0.87 9.2 5.5 1.4 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 CBY13420.1 - 1.8 7.6 12.7 3 6.9 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 CBY13420.1 - 3.6 5.6 13.8 5.1 5.1 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CBY13420.1 - 6 7.3 14.7 12 6.3 14.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VWA PF00092.28 CBY13421.1 - 1.6e-86 289.0 7.2 4.1e-35 121.6 0.0 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 CBY13421.1 - 1e-36 125.8 3.4 6e-14 52.6 0.5 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 CBY13421.1 - 1.2e-10 41.5 0.1 8.3e-06 25.8 0.1 3.2 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY13421.1 - 1.9e-06 27.5 2.9 0.0054 16.2 0.8 3.3 3 0 0 3 3 3 2 VWA domain containing CoxE-like protein DUF2201 PF09967.9 CBY13421.1 - 0.0021 18.2 3.0 4.8 7.3 0.0 3.7 3 1 0 3 3 3 2 VWA-like domain (DUF2201) VWA PF00092.28 CBY13422.1 - 2.2e-54 184.3 1.7 6.4e-33 114.4 0.5 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 CBY13422.1 - 8.6e-22 77.8 0.1 8.9e-13 48.8 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain vWA-TerF-like PF10138.9 CBY13422.1 - 7.4e-10 39.3 0.1 0.0013 18.9 0.1 2.2 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA_3 PF13768.6 CBY13422.1 - 9.6e-10 38.6 0.0 1.6e-05 24.9 0.0 2.4 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY13422.1 - 7.8e-06 25.4 0.1 0.026 13.9 0.0 2.1 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein DUF1194 PF06707.11 CBY13422.1 - 1.2e-05 24.7 0.2 0.034 13.3 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1194) CobT_C PF11775.8 CBY13422.1 - 0.0014 18.4 0.0 2.2 7.9 0.0 2.7 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT VWA domain Copine PF07002.16 CBY13422.1 - 0.0023 17.4 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 2 Copine AhpC-TSA_2 PF13911.6 CBY13422.1 - 0.11 12.6 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme AbrB_C PF18277.1 CBY13423.1 - 0.0055 16.3 0.0 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 AbrB C-terminal domain E1-E2_ATPase PF00122.20 CBY13424.1 - 1.8e-45 154.6 2.3 1.8e-45 154.6 2.3 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBY13424.1 - 1.6e-24 85.8 0.0 3e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY13424.1 - 1.2e-19 71.4 0.2 1.9e-10 41.4 0.0 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBY13424.1 - 3.6e-13 49.0 0.0 6.8e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBY13424.1 - 5.8e-07 29.5 0.5 0.0019 18.0 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY13424.1 - 0.0072 16.7 0.1 0.066 13.6 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cyt_c_ox_IV PF12270.8 CBY13424.1 - 6.6 6.9 6.7 1.1 9.4 2.3 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Glyco_transf_7N PF13733.6 CBY13425.1 - 1.9e-28 98.8 2.3 3.1e-28 98.1 2.3 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY13425.1 - 2.1e-17 62.5 0.3 5.4e-17 61.2 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase SNARE_assoc PF09335.11 CBY13426.1 - 0.036 14.6 0.0 0.061 13.8 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein Not3 PF04065.15 CBY13426.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component MHYT PF03707.16 CBY13426.1 - 0.14 12.3 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat 2OG-FeII_Oxy PF03171.20 CBY13428.1 - 3.2e-19 69.3 0.0 5.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tudor_4 PF18358.1 CBY13428.1 - 0.077 12.6 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain Kelch_5 PF13854.6 CBY13429.1 - 0.038 14.0 3.9 0.14 12.2 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY13429.1 - 0.82 9.7 3.1 2 8.5 0.1 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain zf-CCCH_3 PF15663.5 CBY13430.1 - 0.011 16.0 0.1 0.038 14.2 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger containing family HMG_box_2 PF09011.10 CBY13432.1 - 0.00025 21.6 0.7 0.00042 20.8 0.2 1.7 1 1 1 2 2 2 1 HMG-box domain HMG_box PF00505.19 CBY13432.1 - 0.00047 20.5 0.5 0.00047 20.5 0.5 2.0 1 1 1 2 2 2 1 HMG (high mobility group) box DUF3504 PF12012.8 CBY13432.1 - 0.068 13.1 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) SET PF00856.28 CBY13435.1 - 2.2e-08 34.6 0.0 6.1e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 SET domain Hydrolase_like PF13242.6 CBY13438.1 - 4.1e-18 65.2 0.0 9e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like SAM_1 PF00536.30 CBY13438.1 - 3.3e-06 27.4 0.1 6.7e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 CBY13438.1 - 4.7e-05 23.1 0.0 8.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY13438.1 - 9.7e-05 22.6 0.3 0.00027 21.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain CRIC_ras_sig PF10534.9 CBY13438.1 - 0.016 15.4 0.6 0.14 12.3 0.2 2.5 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras PGP_phosphatase PF09419.10 CBY13438.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase NatB_MDM20 PF09797.9 CBY13440.1 - 1.2e-44 152.8 1.4 2e-44 152.1 1.4 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 CBY13440.1 - 0.018 15.8 0.5 0.86 10.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat COG2 PF06148.11 CBY13440.1 - 0.53 10.4 4.3 0.38 10.8 0.2 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran PF00005.27 CBY13441.1 - 3.4e-31 108.6 0.0 2.5e-15 57.2 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 CBY13441.1 - 1.3e-13 50.5 6.9 2.9e-13 49.4 6.9 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 CBY13441.1 - 4.6e-10 39.3 2.5 0.0028 17.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBY13441.1 - 2.8e-09 37.2 3.7 0.19 11.5 1.1 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 CBY13441.1 - 1.1e-07 31.4 3.6 1.1e-07 31.4 3.6 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 CBY13441.1 - 2e-06 27.8 0.0 0.01 15.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CBY13441.1 - 5.3e-06 26.9 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CBY13441.1 - 9.6e-06 25.5 0.2 0.041 13.6 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CBY13441.1 - 4.3e-05 23.8 0.0 0.034 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CBY13441.1 - 9.6e-05 22.4 0.0 0.095 12.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 CBY13441.1 - 9.6e-05 22.4 0.0 0.0024 17.9 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_6 PF12837.7 CBY13441.1 - 0.00031 20.7 12.5 0.00046 20.1 2.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 CBY13441.1 - 0.00035 20.3 0.1 0.54 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY13441.1 - 0.00039 21.0 0.1 0.072 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CBY13441.1 - 0.00041 20.3 0.3 0.23 11.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 CBY13441.1 - 0.00046 20.6 0.0 0.27 11.6 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CBY13441.1 - 0.00079 19.2 0.1 0.27 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 CBY13441.1 - 0.0015 19.0 1.0 0.0015 19.0 1.0 2.4 1 1 0 2 2 2 1 4Fe-4S dicluster domain AAA_33 PF13671.6 CBY13441.1 - 0.0018 18.4 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBY13441.1 - 0.0018 18.8 0.0 1.6 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBY13441.1 - 0.0019 18.6 0.2 3.7 8.0 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 CBY13441.1 - 0.0033 17.7 0.1 0.72 10.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 CBY13441.1 - 0.0039 17.2 1.0 0.0039 17.2 1.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 CBY13441.1 - 0.004 17.2 12.6 0.0095 16.0 12.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBY13441.1 - 0.0052 16.9 1.4 0.0052 16.9 1.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_30 PF13604.6 CBY13441.1 - 0.0053 16.5 0.9 0.71 9.6 0.1 2.9 4 0 0 4 4 2 1 AAA domain SRP54 PF00448.22 CBY13441.1 - 0.009 15.7 2.8 0.27 10.8 0.2 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_9 PF13187.6 CBY13441.1 - 0.0093 16.1 13.4 0.018 15.2 13.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_7 PF12775.7 CBY13441.1 - 0.015 14.8 0.0 0.74 9.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 CBY13441.1 - 0.017 14.3 0.1 1.5 7.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain Thymidylate_kin PF02223.17 CBY13441.1 - 0.02 14.6 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase Fer4_16 PF13484.6 CBY13441.1 - 0.045 14.7 1.8 0.045 14.7 1.8 2.6 1 1 0 2 2 1 0 4Fe-4S double cluster binding domain AAA_5 PF07728.14 CBY13441.1 - 0.053 13.5 0.1 3.6 7.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 CBY13441.1 - 0.061 13.6 0.0 5.3 7.4 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 CBY13441.1 - 0.068 12.3 0.0 4.8 6.2 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Septin PF00735.18 CBY13441.1 - 0.069 12.4 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.6 CBY13441.1 - 0.084 12.9 0.3 24 5.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 CBY13441.1 - 0.19 11.9 0.3 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CBY13441.1 - 0.21 11.9 0.5 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBY13441.1 - 1.4 9.1 3.1 16 5.6 0.1 3.2 3 1 0 3 3 3 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CBY13441.1 - 1.5 8.7 4.4 51 3.7 0.1 3.9 2 1 2 4 4 4 0 NTPase Fer4_4 PF12800.7 CBY13441.1 - 2.9 8.6 14.8 0.17 12.4 2.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 CBY13441.1 - 3.7 8.1 11.3 0.36 11.3 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBY13441.1 - 3.8 8.1 11.3 0.12 13.0 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Apt1 PF10351.9 CBY13442.1 - 0.0043 16.0 17.3 0.0064 15.4 17.3 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Nab2 PF11517.8 CBY13442.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Menin PF05053.13 CBY13442.1 - 0.11 10.8 8.4 0.13 10.6 8.4 1.1 1 0 0 1 1 1 0 Menin NapB PF03892.14 CBY13442.1 - 2.3 8.2 5.8 0.26 11.3 0.2 2.1 2 1 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) DUF936 PF06075.12 CBY13442.1 - 3.4 6.5 28.1 4.1 6.2 28.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF4614 PF15391.6 CBY13442.1 - 3.5 7.6 25.0 0.49 10.4 16.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) GREB1 PF15782.5 CBY13442.1 - 5.1 4.1 11.4 6 3.8 11.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Dsh_C PF12316.8 CBY13442.1 - 5.7 7.3 15.9 2.5 8.5 12.7 1.9 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal V_ATPase_I PF01496.19 CBY13442.1 - 6.2 4.6 7.0 2.3 6.0 1.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF5099 PF17025.5 CBY13444.1 - 0.022 15.2 0.6 0.026 15.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) zf-C3HC4_2 PF13923.6 CBY13445.1 - 4.6e-07 29.6 9.9 4.6e-07 29.6 9.9 3.2 3 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY13445.1 - 6.5e-06 26.4 11.2 6.5e-06 26.4 11.2 3.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY13445.1 - 1.2e-05 25.2 13.6 0.0003 20.8 3.3 3.5 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY13445.1 - 2.1e-05 24.3 10.7 2.1e-05 24.3 10.7 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY13445.1 - 4e-05 23.4 11.4 4e-05 23.4 11.4 3.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CBY13445.1 - 5.8e-05 22.9 6.5 5.8e-05 22.9 6.5 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CBY13445.1 - 0.00034 20.5 10.2 0.00034 20.5 10.2 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBY13445.1 - 0.00041 20.4 13.6 0.00041 20.4 13.6 3.0 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBY13445.1 - 0.00095 19.0 20.7 0.0014 18.4 9.4 3.2 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 UBZ_FAAP20 PF15750.5 CBY13445.1 - 0.0053 16.7 8.2 0.019 14.9 0.4 3.1 3 0 0 3 3 3 1 Ubiquitin-binding zinc-finger zf-Di19 PF05605.12 CBY13445.1 - 0.085 13.2 21.3 0.091 13.1 1.3 3.7 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.8 CBY13445.1 - 0.11 12.3 16.2 0.073 12.9 7.8 3.0 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit DUF4796 PF16044.5 CBY13445.1 - 1.5 8.4 12.8 0.68 9.5 4.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4796) zinc_ribbon_9 PF14369.6 CBY13445.1 - 1.8 8.9 12.1 2.7 8.3 0.6 3.0 4 0 0 4 4 3 0 zinc-ribbon Kelch_5 PF13854.6 CBY13446.1 - 0.052 13.6 0.3 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Kelch motif DUF3954 PF13128.6 CBY13447.1 - 0.068 13.0 0.2 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) BIR PF00653.21 CBY13448.1 - 3.5e-33 114.1 4.3 7.1e-17 61.8 0.5 2.9 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 CBY13448.1 - 1.6e-11 43.9 8.9 1.6e-11 43.9 8.9 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY13448.1 - 2.3e-06 27.3 8.5 8.3e-06 25.6 8.5 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY13448.1 - 0.0055 17.0 10.7 0.0055 17.0 10.7 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CBY13448.1 - 0.0074 16.2 8.4 0.0074 16.2 8.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain PCI PF01399.27 CBY13449.1 - 0.14 12.7 0.1 0.14 12.7 0.1 2.2 2 1 0 2 2 2 0 PCI domain Pribosyltran PF00156.27 CBY13450.1 - 1.2e-20 73.6 0.0 1.8e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBY13450.1 - 0.0035 16.8 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CBY13450.1 - 0.05 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Opi1 PF08618.10 CBY13450.1 - 0.052 12.8 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 PRTase_3 PF15610.6 CBY13450.1 - 0.064 12.5 0.1 0.24 10.6 0.1 1.8 2 0 0 2 2 2 0 PRTase ComF-like Glyco_transf_90 PF05686.12 CBY13451.1 - 5.6e-66 223.1 0.7 8.3e-66 222.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 CBY13451.1 - 0.046 14.5 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Filamin/ABP280 repeat UAA PF08449.11 CBY13452.1 - 1.9e-77 260.4 21.0 2.2e-77 260.2 21.0 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBY13452.1 - 2.8e-06 26.9 14.7 3.3e-05 23.4 14.7 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 CBY13452.1 - 5.4e-05 22.5 0.3 5.4e-05 22.5 0.3 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter EF1_GNE PF00736.19 CBY13453.1 - 5.4e-33 113.0 1.4 5.4e-33 113.0 1.4 1.5 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CBY13453.1 - 3.4e-14 53.0 5.8 3.4e-14 53.0 5.8 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.12 CBY13453.1 - 0.0055 16.5 3.0 0.007 16.1 3.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Dpy-30 PF05186.13 CBY13454.1 - 5.1e-12 45.3 0.2 8.4e-12 44.6 0.2 1.4 1 1 0 1 1 1 1 Dpy-30 motif Kelch_5 PF13854.6 CBY13455.1 - 0.054 13.5 2.9 2.3 8.3 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 CBY13455.1 - 0.091 12.8 2.9 2.4 8.3 0.0 3.8 4 1 0 4 4 4 0 Kelch motif OAM_dimer PF16554.5 CBY13455.1 - 0.099 13.1 0.1 2.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Gal-3-0_sulfotr PF06990.11 CBY13456.1 - 2.9e-23 82.4 0.0 3.2e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase AA_permease_2 PF13520.6 CBY13457.1 - 1.2e-06 27.6 3.9 1.3e-06 27.5 3.9 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 CBY13457.1 - 0.0061 15.6 3.0 0.0068 15.5 3.0 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3021 PF11457.8 CBY13457.1 - 0.022 15.1 0.5 0.024 14.9 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) AA_permease PF00324.21 CBY13457.1 - 0.052 12.1 7.2 0.065 11.8 7.2 1.0 1 0 0 1 1 1 0 Amino acid permease Yip1 PF04893.17 CBY13457.1 - 0.48 10.1 4.8 0.56 9.9 4.8 1.0 1 0 0 1 1 1 0 Yip1 domain DUF4295 PF14128.6 CBY13458.1 - 0.033 14.0 0.3 0.079 12.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) RnlB_antitoxin PF15933.5 CBY13458.1 - 0.066 13.5 1.1 0.23 11.8 0.1 2.4 2 0 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA PHD PF00628.29 CBY13459.1 - 0.006 16.5 1.8 0.018 14.9 1.8 1.8 1 0 0 1 1 1 1 PHD-finger WRC PF08879.10 CBY13459.1 - 0.075 12.7 0.2 0.32 10.7 0.2 2.0 1 0 0 1 1 1 0 WRC Claudin_2 PF13903.6 CBY13460.1 - 0.00021 21.1 11.8 0.017 14.9 13.2 2.8 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.6 CBY13460.1 - 0.0046 16.8 1.7 0.0066 16.3 0.7 1.8 1 1 1 2 2 2 1 Voltage-dependent calcium channel gamma-like subunit protein family Nitrate_red_gam PF02665.14 CBY13460.1 - 0.011 15.2 0.6 0.017 14.7 0.6 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PsbY PF06298.11 CBY13460.1 - 3.6 7.6 7.5 0.65 9.9 0.4 2.4 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) zf-C3HC4_3 PF13920.6 CBY13461.1 - 2.4e-07 30.5 9.7 3.7e-07 29.9 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY13461.1 - 1.9e-06 27.6 11.5 3.3e-06 26.8 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY13461.1 - 5.8e-06 26.2 10.1 8.8e-06 25.6 10.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY13461.1 - 2.2e-05 24.7 11.6 3.3e-05 24.1 11.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY13461.1 - 0.00012 21.9 11.0 0.0002 21.2 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY13461.1 - 0.00012 21.8 10.8 0.00038 20.3 10.8 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBY13461.1 - 0.002 18.1 5.3 0.002 18.1 5.3 1.8 1 1 1 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.11 CBY13461.1 - 0.0021 18.0 4.1 0.003 17.5 4.0 1.3 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 CBY13461.1 - 0.033 14.0 5.3 0.058 13.3 5.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 CBY13461.1 - 0.11 12.2 8.2 0.22 11.2 8.2 1.5 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_10 PF16685.5 CBY13461.1 - 0.11 12.6 6.2 0.19 11.9 6.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 CBY13461.1 - 0.13 12.6 9.2 0.45 10.8 9.2 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBY13461.1 - 0.44 10.3 7.2 1 9.2 0.9 2.8 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_4 PF14570.6 CBY13461.1 - 0.62 9.9 8.9 1.7 8.5 8.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 CBY13461.1 - 1.3 8.9 9.6 7.8 6.5 9.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 CBY13461.1 - 1.6 8.9 9.7 0.63 10.2 5.4 2.1 1 1 1 2 2 2 0 FYVE zinc finger PhoPQ_related PF10142.9 CBY13462.1 - 3.9e-61 206.8 0.7 4.6e-61 206.5 0.7 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S15 PF02129.18 CBY13462.1 - 0.0024 17.5 0.1 0.0037 16.9 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FlgT_M PF16539.5 CBY13462.1 - 0.017 15.3 0.3 0.028 14.6 0.3 1.2 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain zf-C4 PF00105.18 CBY13463.1 - 8.9e-23 80.5 17.2 2e-22 79.4 17.2 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY13463.1 - 9.1e-12 45.0 11.1 9.4e-12 44.9 8.5 2.3 1 1 1 2 2 2 1 Ligand-binding domain of nuclear hormone receptor adh_short PF00106.25 CBY13464.1 - 5.3e-17 61.9 0.0 7.1e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY13464.1 - 4.1e-10 39.6 0.0 5.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY13464.1 - 0.00025 21.0 0.0 0.00042 20.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY13464.1 - 0.049 13.1 0.0 0.058 12.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GST_N_3 PF13417.6 CBY13466.1 - 6.1e-13 49.0 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBY13466.1 - 1.1e-11 44.9 0.0 3.3e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY13466.1 - 1e-09 38.5 0.1 2e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CBY13466.1 - 9.4e-09 35.5 0.0 1.8e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBY13466.1 - 4.5e-06 26.8 0.3 1e-05 25.6 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY13466.1 - 6.3e-06 26.1 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Vac14_Fig4_bd PF11916.8 CBY13467.1 - 1.7e-50 171.1 0.8 4.4e-50 169.8 0.8 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CBY13467.1 - 2.7e-30 104.8 0.3 3.2e-27 95.0 0.0 3.4 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CBY13467.1 - 1.5e-05 25.4 0.9 0.015 15.8 0.2 4.6 4 1 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 CBY13467.1 - 6.2e-05 22.9 0.9 11 6.6 0.1 5.4 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 CBY13467.1 - 0.0043 17.1 0.5 0.17 11.9 0.1 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF4485 PF14846.6 CBY13467.1 - 0.027 14.5 0.0 0.33 11.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) MARVEL PF01284.23 CBY13468.1 - 0.0047 16.9 11.8 0.014 15.5 11.8 1.7 1 1 0 1 1 1 1 Membrane-associating domain TMEM213 PF15192.6 CBY13468.1 - 0.57 10.2 2.1 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 TMEM213 family DUF1218 PF06749.12 CBY13468.1 - 1.7 9.2 8.8 5.3 7.6 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) MARVEL PF01284.23 CBY13469.1 - 1.5e-10 41.3 13.8 3.8e-10 40.0 13.8 1.7 1 1 0 1 1 1 1 Membrane-associating domain DUF4173 PF13777.6 CBY13469.1 - 0.0093 15.4 2.0 0.0093 15.4 2.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4173) DUF1218 PF06749.12 CBY13469.1 - 7.3 7.2 14.6 59 4.3 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) LRR_4 PF12799.7 CBY13470.1 - 1.1e-19 70.2 12.9 6.1e-07 29.7 2.9 4.4 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY13470.1 - 6.3e-14 51.5 9.5 1.3e-06 28.0 0.8 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CBY13470.1 - 9.4e-07 28.5 8.8 1.1 10.1 0.1 6.7 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY13470.1 - 0.024 14.6 13.8 7.8 6.8 0.2 5.8 6 0 0 6 6 6 0 Leucine Rich repeat Phospholip_A2_1 PF00068.19 CBY13471.1 - 2e-18 66.9 13.0 2e-18 66.9 13.0 2.0 1 1 1 2 2 2 1 Phospholipase A2 VWA_3 PF13768.6 CBY13472.1 - 1.3e-08 35.0 0.0 3.6e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CBY13472.1 - 2.6e-05 24.6 0.0 0.00012 22.4 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY13472.1 - 0.025 15.2 0.0 0.2 12.3 0.0 2.4 1 1 0 1 1 1 0 von Willebrand factor type A domain FAM177 PF14774.6 CBY13472.1 - 0.084 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 FAM177 family O-FucT PF10250.9 CBY13474.1 - 1.8e-12 47.7 0.0 2.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase EGF_CA PF07645.15 CBY13475.1 - 4.6e-19 68.4 22.7 2.7e-10 40.3 8.0 3.8 3 0 0 3 3 3 2 Calcium-binding EGF domain EGF_3 PF12947.7 CBY13475.1 - 0.0011 19.1 15.1 0.18 12.1 3.0 3.0 2 0 0 2 2 2 2 EGF domain EGF_MSP1_1 PF12946.7 CBY13475.1 - 0.11 12.5 8.4 2.2 8.4 1.1 2.8 2 0 0 2 2 2 0 MSP1 EGF domain 1 cEGF PF12662.7 CBY13475.1 - 0.29 11.1 19.4 0.058 13.3 3.5 4.2 4 0 0 4 4 4 0 Complement Clr-like EGF-like hEGF PF12661.7 CBY13475.1 - 2.2 9.0 17.0 0.31 11.7 2.1 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF Pro_isomerase PF00160.21 CBY13476.1 - 2.7e-51 174.0 0.0 3.2e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Complex1_49kDa PF00346.19 CBY13477.1 - 1.2e-118 395.1 0.0 1.6e-118 394.7 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CBY13477.1 - 0.051 12.5 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase p450 PF00067.22 CBY13478.1 - 1.2e-08 34.1 0.0 1.4e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CBY13479.1 - 5e-51 173.9 0.0 6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CBY13480.1 - 1.2e-67 228.6 0.0 1.4e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NERD PF08378.11 CBY13481.1 - 1.3e-12 48.1 0.1 2.3e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Nuclease-related domain PepSY_like PF11396.8 CBY13481.1 - 0.017 15.6 0.2 0.06 13.9 0.1 2.0 1 1 0 1 1 1 0 Putative beta-lactamase-inhibitor-like, PepSY-like PDDEXK_9 PF08011.11 CBY13481.1 - 0.052 13.5 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily CENP-F_leu_zip PF10473.9 CBY13482.1 - 0.00022 21.2 10.4 0.00022 21.2 10.4 3.2 2 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 CBY13482.1 - 0.0024 18.4 10.3 0.0024 18.4 10.3 3.1 2 1 1 3 3 3 2 Apg6 coiled-coil region T2SSG PF08334.11 CBY13482.1 - 0.083 13.0 0.3 0.29 11.2 0.3 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G DHR10 PF18595.1 CBY13482.1 - 0.43 10.7 28.6 0.081 13.0 8.3 3.7 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain TolA_bind_tri PF16331.5 CBY13482.1 - 0.46 10.6 14.4 0.054 13.6 1.3 4.2 2 1 2 4 4 4 0 TolA binding protein trimerisation Phage_GP20 PF06810.11 CBY13482.1 - 1.8 8.3 29.9 1 9.1 8.5 3.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Cep57_MT_bd PF06657.13 CBY13482.1 - 2 8.9 18.7 3.4 8.2 2.4 4.2 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 TPR_MLP1_2 PF07926.12 CBY13482.1 - 2.4 8.2 30.9 2.2 8.4 11.7 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.9 CBY13482.1 - 9.6 4.6 27.9 12 4.3 27.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF1295 PF06966.12 CBY13484.1 - 5.3e-50 170.1 1.7 6.2e-50 169.9 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 CBY13484.1 - 0.0014 19.0 0.2 0.005 17.2 0.0 2.1 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CBY13484.1 - 0.0018 18.7 2.5 0.0018 18.7 0.3 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 CBY13484.1 - 0.0035 17.3 2.3 0.0052 16.8 0.7 2.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase MerC PF03203.14 CBY13484.1 - 0.041 14.3 0.3 0.041 14.3 0.3 1.8 2 0 0 2 2 2 0 MerC mercury resistance protein Tetraspanin PF00335.20 CBY13485.1 - 0.0055 16.5 1.1 0.0065 16.2 1.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Phage_Treg PF04761.12 CBY13485.1 - 0.11 12.7 0.1 3 8.0 0.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator DUF4898 PF16239.5 CBY13485.1 - 0.18 11.8 0.8 2.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4898) LIAS_N PF16881.5 CBY13486.1 - 0.24 11.8 0.3 11 6.5 0.0 2.4 1 1 1 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family Sulfatase PF00884.23 CBY13487.1 - 1.7e-51 175.4 0.4 6.9e-51 173.5 0.4 1.8 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CBY13487.1 - 4.7e-06 26.8 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 CBY13487.1 - 6.2e-06 26.0 0.1 0.00024 20.8 0.1 2.4 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CBY13487.1 - 0.00023 19.9 0.0 0.0023 16.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF229) AvrB_AvrC PF05394.11 CBY13487.1 - 0.025 13.8 0.1 0.037 13.2 0.1 1.2 1 0 0 1 1 1 0 Avirulence protein Sulfatase_C PF14707.6 CBY13487.1 - 0.039 14.7 0.0 3.3 8.4 0.0 2.6 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 CBY13487.1 - 0.067 12.2 0.4 0.15 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) DUF4994 PF16385.5 CBY13487.1 - 0.084 12.8 0.1 1.1 9.2 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function UQ_con PF00179.26 CBY13489.1 - 1e-41 141.8 0.0 1.3e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY13489.1 - 0.06 13.0 0.0 0.3 10.8 0.0 2.1 2 1 0 2 2 2 0 Prokaryotic E2 family B IF4E PF01652.18 CBY13490.1 - 1.1e-54 184.6 1.4 1.3e-54 184.3 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 CBY13491.1 - 1.1e-63 215.2 0.0 1.2e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13491.1 - 4.3e-29 101.6 0.0 7.1e-29 100.9 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CBY13491.1 - 4.1e-07 29.6 0.7 6.5e-07 28.9 0.7 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY13491.1 - 3.1e-05 24.0 0.1 0.00088 19.3 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY13491.1 - 0.00092 18.6 0.1 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBY13491.1 - 0.0049 16.5 0.4 0.008 15.8 0.4 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CBY13491.1 - 0.038 13.0 0.1 0.068 12.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Zona_pellucida PF00100.23 CBY13494.1 - 1.2e-27 97.4 7.1 1.5e-27 97.0 7.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain RGS PF00615.19 CBY13496.1 - 3e-23 82.3 0.1 1e-22 80.6 0.1 1.7 1 1 1 2 2 2 1 Regulator of G protein signaling domain Thioredoxin PF00085.20 CBY13497.1 - 1e-26 92.9 0.3 1.1e-26 92.7 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBY13497.1 - 9.1e-05 22.6 0.2 0.00012 22.2 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CBY13497.1 - 0.00084 19.6 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CBY13497.1 - 0.0033 16.8 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBY13497.1 - 0.0054 17.2 0.2 0.038 14.4 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY13497.1 - 0.0069 16.3 0.1 0.0083 16.0 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY13497.1 - 0.027 14.2 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 CBY13497.1 - 0.036 14.3 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin PDEase_I PF00233.19 CBY13498.1 - 1.7e-77 260.3 6.3 3.5e-77 259.4 6.3 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Presenilin PF01080.17 CBY13498.1 - 2.8 6.6 11.4 4.4 6.0 11.4 1.2 1 0 0 1 1 1 0 Presenilin SET PF00856.28 CBY13499.1 - 1.1e-10 42.2 1.8 3.3e-10 40.6 1.8 1.7 1 1 0 1 1 1 1 SET domain RPAP2_Rtr1 PF04181.13 CBY13499.1 - 0.049 14.0 0.4 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 Rtr1/RPAP2 family SNF PF00209.18 CBY13500.1 - 8.3e-69 232.7 6.0 9.4e-69 232.5 6.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4131 PF13567.6 CBY13500.1 - 0.64 9.7 4.0 3.1 7.4 1.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) PDEase_I PF00233.19 CBY13501.1 - 1.8e-52 178.4 0.6 3.8e-52 177.4 0.6 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-U11-48K PF05253.12 CBY13501.1 - 0.52 10.3 1.7 0.84 9.6 0.3 2.2 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Presenilin PF01080.17 CBY13501.1 - 0.97 8.1 9.6 1.4 7.6 9.6 1.2 1 0 0 1 1 1 0 Presenilin SET PF00856.28 CBY13502.1 - 4.8e-07 30.3 0.4 5.4e-07 30.1 0.4 1.2 1 0 0 1 1 1 1 SET domain Poxvirus PF06227.12 CBY13502.1 - 0.052 13.3 1.2 0.09 12.5 1.2 1.6 1 1 0 1 1 1 0 dsDNA Poxvirus SNF PF00209.18 CBY13504.1 - 5.7e-176 586.3 26.4 6.5e-176 586.1 26.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LRR_8 PF13855.6 CBY13505.1 - 5e-30 103.0 33.1 4.7e-08 32.7 3.4 5.8 2 2 4 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 CBY13505.1 - 4.8e-19 68.6 38.5 1.4e-09 38.0 7.5 2.7 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY13505.1 - 9.7e-16 57.6 44.7 0.00057 20.2 0.8 7.4 2 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY13505.1 - 7.1e-10 38.7 17.3 0.00016 21.2 3.8 3.7 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CBY13505.1 - 3.9e-05 23.6 21.2 0.15 12.7 0.1 8.8 8 3 0 8 8 8 1 Leucine Rich Repeat Pox_D2 PF04701.13 CBY13505.1 - 0.43 10.8 10.6 0.089 13.0 1.1 3.4 2 1 1 4 4 4 0 Pox virus D2 protein Rad52_Rad22 PF04098.15 CBY13505.1 - 0.6 10.0 3.3 2.6 8.0 0.6 2.2 1 1 0 2 2 2 0 Rad52/22 family double-strand break repair protein DUF3557 PF12078.8 CBY13505.1 - 0.61 10.0 16.7 0.11 12.5 3.5 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3557) LRR_6 PF13516.6 CBY13505.1 - 4.1 7.7 30.8 10 6.5 0.1 8.1 10 0 0 10 10 10 0 Leucine Rich repeat DUF5344 PF17279.2 CBY13506.1 - 0.032 14.8 0.3 0.032 14.8 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Borrelia_P83 PF05262.11 CBY13506.1 - 5.2 5.4 23.7 3 6.2 17.3 2.2 2 0 0 2 2 2 0 Borrelia P83/100 protein CaKB PF03185.15 CBY13507.1 - 2.9e-14 53.2 4.5 1.1e-11 44.8 0.4 2.1 2 0 0 2 2 2 2 Calcium-activated potassium channel, beta subunit RVT_1 PF00078.27 CBY13509.1 - 0.0023 17.5 1.9 0.0042 16.6 0.0 2.5 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_UL6 PF01763.16 CBY13509.1 - 0.0026 16.4 0.8 0.0053 15.3 0.8 1.6 1 0 0 1 1 1 1 Herpesvirus UL6 like Exo_endo_phos_2 PF14529.6 CBY13509.1 - 0.0096 15.8 0.6 0.041 13.7 0.6 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Cortex-I_coil PF09304.10 CBY13509.1 - 0.064 13.5 0.2 0.28 11.4 0.2 2.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil Sigma70_r3 PF04539.16 CBY13509.1 - 0.45 10.6 3.1 0.58 10.3 0.2 2.5 2 0 0 2 2 2 0 Sigma-70 region 3 Antimicrobial25 PF16839.5 CBY13511.1 - 2.9 8.1 10.7 1.7 8.8 8.5 1.8 1 1 0 1 1 1 0 Nematode antimicrobial peptide FYVE PF01363.21 CBY13511.1 - 3 8.0 14.7 36 4.6 15.1 2.1 1 1 0 1 1 1 0 FYVE zinc finger Borrelia_P83 PF05262.11 CBY13513.1 - 0.14 10.6 17.6 0.16 10.4 17.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Atg14 PF10186.9 CBY13513.1 - 1.7 7.7 17.6 2.4 7.2 17.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CaKB PF03185.15 CBY13514.1 - 4e-17 62.5 7.6 1.7e-11 44.1 0.4 2.1 2 0 0 2 2 2 2 Calcium-activated potassium channel, beta subunit p47_phox_C PF08944.11 CBY13516.1 - 2.7 7.5 16.1 0.13 11.7 4.0 2.6 1 1 1 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Pkinase PF00069.25 CBY13517.1 - 1.4e-30 106.6 0.1 1.7e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13517.1 - 1e-22 80.7 0.1 1.2e-22 80.5 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBY13517.1 - 0.013 15.2 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CBY13517.1 - 0.051 12.9 0.5 0.072 12.4 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_int_SAM_1 PF02899.17 CBY13517.1 - 0.17 12.2 0.5 1.4 9.3 0.1 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain STAT_bind PF02864.15 CBY13519.1 - 5.2e-38 130.6 0.1 5.2e-38 130.6 0.1 2.7 2 1 1 3 3 3 1 STAT protein, DNA binding domain STAT_int PF02865.17 CBY13519.1 - 2.5e-27 95.8 0.1 2.5e-27 95.8 0.1 3.0 2 1 2 4 4 4 1 STAT protein, protein interaction domain STAT_alpha PF01017.20 CBY13519.1 - 4.9e-17 62.4 12.5 1.3e-16 61.0 12.5 1.7 1 0 0 1 1 1 1 STAT protein, all-alpha domain SH2 PF00017.24 CBY13519.1 - 2.2e-07 30.9 0.1 1.2e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 SH2 domain GSCFA PF08885.11 CBY13519.1 - 0.06 13.0 5.5 0.25 10.9 5.9 1.8 2 0 0 2 2 2 0 GSCFA family DUF484 PF04340.12 CBY13519.1 - 0.7 9.5 7.1 44 3.7 6.5 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF484 Lactamase_B PF00753.27 CBY13520.1 - 1.4e-15 57.9 3.2 1.1e-13 51.7 3.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY13520.1 - 0.004 16.7 0.1 0.0059 16.2 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CUB PF00431.20 CBY13521.1 - 1.6e-06 28.4 0.0 2.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 CUB domain ADH_N PF08240.12 CBY13522.1 - 1.4e-28 99.0 4.9 2.9e-28 97.9 4.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CBY13522.1 - 5.9e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 CBY13522.1 - 2.2e-07 30.9 0.0 4.7e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase RELT PF12606.8 CBY13522.1 - 0.088 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 VWD PF00094.25 CBY13524.1 - 4.3e-51 173.3 19.1 6.8e-13 49.2 0.4 7.6 6 1 0 6 6 6 6 von Willebrand factor type D domain C8 PF08742.11 CBY13524.1 - 3.3e-09 37.0 65.8 0.00011 22.5 3.2 7.1 5 2 2 7 7 7 4 C8 domain TIL PF01826.17 CBY13524.1 - 2e-07 31.2 71.6 0.00011 22.3 10.5 8.3 9 0 0 9 9 9 4 Trypsin Inhibitor like cysteine rich domain SNF2_N PF00176.23 CBY13525.1 - 2.1e-45 155.0 1.1 3.7e-45 154.2 1.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY13525.1 - 9.5e-21 74.2 0.3 1.8e-17 63.7 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CBY13525.1 - 2.2e-12 47.3 0.1 4.8e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CBY13525.1 - 1.1e-07 31.4 0.2 3.2e-07 29.8 0.2 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.6 CBY13525.1 - 0.00037 19.5 0.1 0.001 18.0 0.1 1.6 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 CBY13525.1 - 0.00045 20.0 0.0 0.00097 18.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CBY13525.1 - 0.00069 18.9 0.1 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase Fe-S_assembly PF04384.13 CBY13525.1 - 0.042 14.5 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 Iron-sulphur cluster assembly CENP-K PF11802.8 CBY13525.1 - 0.36 10.4 3.3 0.78 9.3 0.1 2.2 2 0 0 2 2 2 0 Centromere-associated protein K Presenilin PF01080.17 CBY13526.1 - 5.8 5.6 4.8 5.8 5.6 4.8 1.1 1 0 0 1 1 1 0 Presenilin RasGAP PF00616.19 CBY13528.1 - 1.9e-10 40.8 0.1 3.3e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase 14-3-3 PF00244.20 CBY13529.1 - 2.7e-106 354.0 3.1 3.1e-106 353.9 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein CodY PF06018.14 CBY13529.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 CodY GAF-like domain Virulence_fact PF13769.6 CBY13529.1 - 1.2 9.4 4.7 0.7 10.2 0.6 2.6 3 0 0 3 3 3 0 Virulence factor Rod-binding PF10135.9 CBY13530.1 - 0.07 13.7 0.6 0.32 11.6 0.0 2.5 3 0 0 3 3 3 0 Rod binding protein Pkinase PF00069.25 CBY13531.1 - 4.8e-22 78.6 0.1 5.7e-22 78.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13531.1 - 9.8e-19 67.6 0.0 1.2e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY13531.1 - 0.048 13.0 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pox_A32 PF04665.12 CBY13533.1 - 0.0032 17.0 3.4 0.016 14.7 0.0 2.3 2 1 0 2 2 2 1 Poxvirus A32 protein ATPase PF06745.13 CBY13533.1 - 0.0048 16.3 0.7 0.17 11.2 0.0 2.3 2 1 0 2 2 2 1 KaiC AAA_24 PF13479.6 CBY13533.1 - 0.018 14.8 0.1 0.036 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBY13533.1 - 0.023 14.0 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 CBY13533.1 - 0.026 14.2 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 CBY13533.1 - 0.041 14.0 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBY13533.1 - 0.048 12.8 0.1 0.36 10.0 0.1 2.0 1 1 1 2 2 2 0 NB-ARC domain NACHT PF05729.12 CBY13533.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CBY13533.1 - 0.096 13.0 0.1 0.28 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBY13533.1 - 0.11 12.3 0.0 18 5.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Peptidase_S9 PF00326.21 CBY13535.1 - 3.1e-10 39.9 0.1 3.3e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CBY13535.1 - 0.043 13.6 0.1 0.051 13.4 0.1 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Kelch_6 PF13964.6 CBY13537.1 - 0.091 13.1 12.1 22 5.5 0.1 5.8 6 0 0 6 6 6 0 Kelch motif Sporozoite_P67 PF05642.11 CBY13537.1 - 0.28 9.2 4.5 0.45 8.5 4.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 CBY13537.1 - 0.46 10.5 42.0 0.83 9.6 42.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 CBY13537.1 - 0.52 10.8 13.8 1.2 9.6 13.8 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Kelch_2 PF07646.15 CBY13537.1 - 0.95 9.5 15.0 22 5.2 0.2 5.6 6 0 0 6 6 6 0 Kelch motif DPPIV_N PF00930.21 CBY13538.1 - 5.5e-05 22.1 0.1 0.00015 20.6 0.0 1.7 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Piwi PF02171.17 CBY13540.1 - 1.8e-61 208.0 0.0 2.5e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CBY13540.1 - 5.4e-06 26.3 0.0 9.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 CBY13540.1 - 6.5e-06 26.3 0.5 2.4e-05 24.5 0.5 2.0 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 CBY13540.1 - 0.00079 19.7 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain TcdB_N PF12918.7 CBY13540.1 - 0.064 13.6 0.7 3 8.2 0.0 2.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Kelch_2 PF07646.15 CBY13541.1 - 7.5e-08 32.1 0.3 0.079 13.0 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY13541.1 - 6.4e-07 29.4 1.1 0.23 11.8 0.0 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY13541.1 - 0.00015 21.7 6.0 0.57 10.2 0.0 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CBY13541.1 - 0.00065 19.2 0.3 3.9 7.2 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CBY13541.1 - 0.00085 19.6 3.1 3.1 8.2 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY13541.1 - 0.052 13.6 5.8 1.1 9.3 0.0 4.4 5 0 0 5 5 5 0 Galactose oxidase, central domain cEGF PF12662.7 CBY13545.1 - 0.0025 17.7 3.1 0.0067 16.3 3.1 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY13545.1 - 0.017 15.4 2.7 0.051 13.9 2.7 1.9 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Gla PF00594.20 CBY13546.1 - 1e-10 41.6 4.7 1e-10 41.6 4.7 1.6 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain HflK_N PF12221.8 CBY13546.1 - 0.079 13.0 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial membrane protein N terminal adh_short PF00106.25 CBY13548.1 - 3.8e-24 85.2 0.6 7.1e-20 71.3 0.2 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY13548.1 - 1.7e-16 60.5 2.0 6.9e-14 52.0 0.4 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY13548.1 - 9.2e-08 32.2 0.1 1.6e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY13548.1 - 0.00023 20.7 0.2 0.00038 20.0 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CBY13548.1 - 0.077 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 CBY13549.1 - 3.8e-30 105.0 12.0 5.7e-30 104.4 12.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY13549.1 - 0.027 13.3 11.0 11 4.8 11.0 2.3 1 1 0 1 1 1 0 MFS_1 like family PH PF00169.29 CBY13549.1 - 0.091 13.3 0.2 0.41 11.2 0.1 2.0 2 0 0 2 2 2 0 PH domain Phage_holin_2_3 PF16080.5 CBY13549.1 - 2 8.2 4.7 1 9.1 0.6 2.7 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Sulfotransfer_1 PF00685.27 CBY13550.1 - 1.9e-08 34.1 0.4 1.8e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY13550.1 - 2.3e-05 24.9 0.0 3.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family LRR_8 PF13855.6 CBY13551.1 - 1.1e-62 207.6 72.0 2.4e-12 46.4 3.7 11.0 5 4 7 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 CBY13551.1 - 1.6e-31 107.8 81.4 2.4e-06 27.7 1.1 12.5 10 1 3 13 13 13 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY13551.1 - 1.2e-22 80.2 18.1 2e-06 27.8 0.2 5.5 6 0 0 6 6 6 4 BspA type Leucine rich repeat region (6 copies) EGF PF00008.27 CBY13551.1 - 6.4e-19 67.9 130.6 2.5e-07 30.9 6.1 12.5 12 1 0 12 12 11 7 EGF-like domain LRR_9 PF14580.6 CBY13551.1 - 1.9e-18 66.6 33.1 6.1e-06 25.9 1.8 6.6 4 3 3 7 7 7 6 Leucine-rich repeat Laminin_G_1 PF00054.23 CBY13551.1 - 2.2e-12 47.3 0.1 3.6e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 CBY13551.1 - 3.3e-11 43.8 0.0 6.4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain LRR_1 PF00560.33 CBY13551.1 - 3.5e-05 23.8 51.9 3 8.8 0.2 15.1 16 0 0 16 16 15 2 Leucine Rich Repeat LRRCT PF01463.24 CBY13551.1 - 0.00018 21.8 0.4 18 6.2 0.0 4.3 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain hEGF PF12661.7 CBY13551.1 - 0.00056 20.5 5.5 0.00056 20.5 5.5 13.0 12 1 0 12 12 10 6 Human growth factor-like EGF EGF_2 PF07974.13 CBY13551.1 - 0.00069 19.9 9.1 0.00069 19.9 9.1 12.9 13 0 0 13 13 11 7 EGF-like domain EGF_CA PF07645.15 CBY13551.1 - 0.00076 19.6 5.9 0.00076 19.6 5.9 12.1 9 2 3 13 13 10 2 Calcium-binding EGF domain LRR_6 PF13516.6 CBY13551.1 - 0.14 12.3 21.1 29 5.0 0.3 9.2 9 0 0 9 9 9 0 Leucine Rich repeat adh_short_C2 PF13561.6 CBY13552.1 - 4.6e-50 170.4 0.1 5.8e-50 170.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY13552.1 - 2.3e-47 161.0 0.1 2.9e-47 160.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY13552.1 - 6.8e-14 52.2 0.1 1e-13 51.6 0.1 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CBY13552.1 - 0.00063 18.9 0.0 0.00097 18.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CBY13552.1 - 0.0027 17.6 0.1 0.0036 17.2 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 CBY13552.1 - 0.048 13.5 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 CBY13552.1 - 0.12 11.7 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) PDH PF02153.17 CBY13552.1 - 0.13 11.2 0.2 8.4 5.3 0.0 2.7 3 0 0 3 3 3 0 Prephenate dehydrogenase Na_sulph_symp PF00939.19 CBY13553.1 - 1.1e-25 90.6 1.5 1.5e-25 90.2 1.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY13553.1 - 2.3e-12 46.8 10.6 3.2e-12 46.3 10.6 1.1 1 0 0 1 1 1 1 Citrate transporter DUF5378 PF17349.2 CBY13554.1 - 0.0061 15.9 0.4 0.0072 15.7 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5378) DUF1774 PF08611.10 CBY13554.1 - 0.038 14.3 0.3 0.046 14.0 0.3 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1774) Trypsin PF00089.26 CBY13555.1 - 2.1e-41 142.2 1.0 3.1e-41 141.6 1.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY13555.1 - 3.9e-05 24.6 0.8 7.1e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF732 PF05305.14 CBY13555.1 - 0.013 15.9 0.1 0.051 14.0 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF732) DUF1833 PF08875.11 CBY13555.1 - 0.074 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) Sushi PF00084.20 CBY13555.1 - 3.1 8.5 10.0 0.096 13.3 2.2 2.4 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) CUB PF00431.20 CBY13556.1 - 0.23 11.8 2.7 0.22 11.9 0.3 2.0 2 1 0 2 2 2 0 CUB domain AA_permease_2 PF13520.6 CBY13557.1 - 1.2e-19 70.4 17.6 1.4e-19 70.3 17.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY13557.1 - 4.9e-05 22.1 15.3 5.3e-05 22.0 15.3 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_S37 PF05576.11 CBY13557.1 - 0.21 10.2 0.3 0.26 9.9 0.3 1.0 1 0 0 1 1 1 0 PS-10 peptidase S37 Lzipper-MIP1 PF14389.6 CBY13558.1 - 0.095 13.0 1.1 7.4 6.9 0.0 3.3 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Pkinase PF00069.25 CBY13560.1 - 1.7e-09 37.5 1.8 2e-09 37.2 0.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13560.1 - 4.6e-07 29.4 0.1 8.5e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY13561.1 - 2.1e-12 47.0 0.3 4.8e-12 45.8 0.3 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13561.1 - 1.4e-07 31.1 0.0 3.1e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.6 CBY13561.1 - 0.34 11.1 4.7 3.4 7.9 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3896) MARVEL PF01284.23 CBY13563.1 - 2e-06 27.9 11.7 2.4e-06 27.6 11.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Colicin_V PF02674.16 CBY13563.1 - 0.02 14.9 6.1 0.027 14.4 6.1 1.3 1 0 0 1 1 1 0 Colicin V production protein Wzy_C PF04932.15 CBY13563.1 - 0.077 12.6 2.1 1.2 8.7 1.0 2.1 1 1 1 2 2 2 0 O-Antigen ligase DUF1211 PF06736.11 CBY13563.1 - 0.077 13.4 1.8 0.14 12.6 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) Lectin_C PF00059.21 CBY13564.1 - 0.019 15.7 7.0 0.38 11.5 7.0 2.4 1 1 0 1 1 1 0 Lectin C-type domain Nucleoporin_FG2 PF15967.5 CBY13564.1 - 0.28 9.7 0.1 0.38 9.2 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region SRA1 PF07304.11 CBY13565.1 - 2.4 7.9 5.6 0.37 10.6 0.7 2.1 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) RVT_1 PF00078.27 CBY13566.1 - 1.7e-28 99.7 0.0 1.7e-26 93.1 0.0 3.0 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_2 PF07646.15 CBY13568.1 - 0.00011 22.0 0.7 1 9.4 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY13568.1 - 0.036 14.1 0.4 15 5.7 0.1 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY13568.1 - 0.044 14.1 1.5 0.78 10.1 0.1 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY13568.1 - 0.079 13.0 0.4 0.74 9.9 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 CBY13569.1 - 0.21 11.6 2.0 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain EF-hand_1 PF00036.32 CBY13570.1 - 3.6e-17 60.5 1.0 2.6e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY13570.1 - 1.8e-14 52.3 1.7 1.7e-06 27.5 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBY13570.1 - 7.4e-14 52.0 0.8 9e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY13570.1 - 4.6e-13 48.0 1.5 8e-06 25.1 1.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY13570.1 - 7.9e-10 38.4 2.0 9e-05 22.3 0.4 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 CBY13570.1 - 6.7e-05 22.8 1.4 0.005 16.8 0.0 2.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY13570.1 - 0.0016 18.8 0.2 0.036 14.4 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.11 CBY13570.1 - 0.11 12.6 0.0 9.2 6.4 0.0 2.1 2 0 0 2 2 2 0 EF hand Kelch_5 PF13854.6 CBY13571.1 - 0.0067 16.4 2.4 0.009 16.0 0.0 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CBY13571.1 - 0.12 12.4 0.4 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 CBY13572.1 - 0.1 12.9 0.2 7.4 7.0 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY13572.1 - 0.34 10.9 0.0 0.34 10.9 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY13573.1 - 0.039 13.9 2.0 0.22 11.5 0.0 3.1 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CBY13573.1 - 0.067 13.2 0.9 20 5.4 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY13573.1 - 0.11 12.8 2.0 0.66 10.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 CBY13574.1 - 0.00035 20.4 0.2 0.095 12.7 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY13574.1 - 0.016 15.5 0.5 0.72 10.2 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY13574.1 - 0.025 14.6 0.0 9.4 6.3 0.0 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY13575.1 - 1.2e-06 28.2 0.8 2 8.5 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CBY13575.1 - 6.6e-06 26.2 2.7 2.1 8.8 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 CBY13575.1 - 0.017 15.1 1.9 11 6.1 0.0 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain CCDC85 PF10226.9 CBY13575.1 - 0.02 14.6 0.9 5.8 6.6 0.0 2.6 3 0 0 3 3 3 0 CCDC85 family OAM_dimer PF16554.5 CBY13575.1 - 0.15 12.5 0.0 11 6.6 0.0 2.5 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Kelch_5 PF13854.6 CBY13575.1 - 0.19 11.8 0.1 0.19 11.8 0.1 4.3 6 0 0 6 6 6 0 Kelch motif DUF3439 PF11921.8 CBY13575.1 - 4.9 7.1 11.5 4.8 7.2 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Lectin_C PF00059.21 CBY13576.1 - 3.9e-21 75.8 5.4 6.7e-12 46.1 0.1 2.4 2 0 0 2 2 2 2 Lectin C-type domain Trefoil PF00088.18 CBY13576.1 - 0.0074 16.2 4.9 0.022 14.6 4.9 1.9 1 0 0 1 1 1 1 Trefoil (P-type) domain Trefoil PF00088.18 CBY13577.1 - 0.0028 17.5 4.7 0.0049 16.7 4.7 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain Kelch_2 PF07646.15 CBY13578.1 - 0.0025 17.7 0.6 0.75 9.9 0.0 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CBY13578.1 - 0.047 13.7 3.6 0.96 9.5 0.0 3.8 5 0 0 5 5 5 0 Kelch motif CppA_N PF14506.6 CBY13578.1 - 0.078 13.1 0.5 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 CppA N-terminal Kelch_6 PF13964.6 CBY13578.1 - 0.083 13.2 0.4 5.3 7.5 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY13578.1 - 0.11 12.5 0.3 35 4.5 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain PFU PF09070.11 CBY13578.1 - 0.18 12.1 1.9 0.43 10.8 0.2 2.4 3 0 0 3 3 3 0 PFU (PLAA family ubiquitin binding) Trypsin PF00089.26 CBY13579.1 - 9.9e-89 296.9 0.0 2.5e-48 164.8 0.0 2.2 2 0 0 2 2 2 2 Trypsin p450 PF00067.22 CBY13579.1 - 6.2e-21 74.7 0.3 8.8e-21 74.2 0.3 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1986 PF09342.11 CBY13579.1 - 9.5e-06 26.0 0.0 0.0019 18.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) DUF316 PF03761.15 CBY13579.1 - 0.00028 20.5 0.0 0.4 10.2 0.0 2.5 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DUF1161 PF06649.12 CBY13579.1 - 0.026 14.7 0.3 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) RVT_1 PF00078.27 CBY13580.1 - 6.2e-12 45.5 0.5 1.8e-11 44.0 0.2 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CBY13580.1 - 1.3e-09 38.0 0.0 7e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY13580.1 - 8.2e-07 29.3 0.2 4.5e-06 26.9 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY13580.1 - 5.8e-05 23.1 0.3 5.8e-05 23.1 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 CBY13580.1 - 0.0011 19.6 0.0 0.0027 18.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY13580.1 - 0.15 12.6 0.0 0.56 10.8 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CUB PF00431.20 CBY13582.1 - 2.3e-11 44.0 0.2 1.2e-09 38.5 0.2 2.4 2 0 0 2 2 2 2 CUB domain MIP PF00230.20 CBY13585.1 - 1.7e-14 54.1 0.1 2e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein TMEM144 PF07857.12 CBY13585.1 - 0.06 12.3 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters MFS_1 PF07690.16 CBY13586.1 - 5e-19 68.4 31.9 5.6e-19 68.3 31.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Trypsin PF00089.26 CBY13587.1 - 4.4e-52 177.1 2.2 5.7e-27 95.0 0.8 2.4 2 0 0 2 2 2 2 Trypsin Kringle PF00051.18 CBY13587.1 - 5.1e-23 81.2 3.5 5.1e-23 81.2 3.5 2.5 2 0 0 2 2 2 1 Kringle domain DUF1986 PF09342.11 CBY13587.1 - 0.052 13.9 0.0 0.3 11.5 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1986) Integrase_DNA PF02920.15 CBY13588.1 - 0.32 10.7 0.7 0.7 9.6 0.7 1.5 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Nnf1 PF03980.14 CBY13589.1 - 0.11 12.9 0.5 0.11 12.9 0.5 1.5 2 0 0 2 2 2 0 Nnf1 COesterase PF00135.28 CBY13590.1 - 1e-58 199.5 0.0 2.4e-56 191.7 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family ESSS PF10183.9 CBY13590.1 - 0.00018 21.7 0.6 0.72 10.1 0.0 2.3 2 0 0 2 2 2 2 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Abhydrolase_3 PF07859.13 CBY13590.1 - 0.0012 18.7 0.0 0.0042 17.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Memo PF01875.17 CBY13590.1 - 0.0075 15.4 0.0 2.7 7.0 0.0 2.1 2 0 0 2 2 2 2 Memo-like protein Lig_chan PF00060.26 CBY13592.1 - 3.5e-33 114.6 1.6 5.5e-33 113.9 1.6 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CBY13592.1 - 2.4e-32 111.5 0.2 4.1e-32 110.8 0.2 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CBY13592.1 - 5e-26 91.5 0.0 9.6e-26 90.6 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 zf-RING_2 PF13639.6 CBY13593.1 - 1.3e-10 41.4 3.1 2.4e-10 40.6 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY13593.1 - 2.3e-09 36.9 3.6 4.7e-09 35.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY13593.1 - 1.1e-07 31.6 3.0 2.3e-07 30.6 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY13593.1 - 5.2e-06 26.7 2.2 1.7e-05 25.0 2.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY13593.1 - 8.3e-06 25.6 1.7 1.4e-05 24.9 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY13593.1 - 2.9e-05 23.9 3.8 5.5e-05 23.0 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY13593.1 - 8.2e-05 22.5 4.7 8.2e-05 22.5 4.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger GAS PF13851.6 CBY13593.1 - 0.0021 17.4 81.1 0.06 12.7 17.6 4.2 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding zf-RING_11 PF17123.5 CBY13593.1 - 0.0023 17.6 3.3 0.019 14.7 1.0 2.7 2 0 0 2 2 2 1 RING-like zinc finger Golgin_A5 PF09787.9 CBY13593.1 - 0.0024 17.4 18.2 0.0024 17.4 18.2 3.7 1 1 3 4 4 3 1 Golgin subfamily A member 5 Baculo_IE-1 PF05290.11 CBY13593.1 - 0.0082 16.1 0.9 0.0082 16.1 0.9 2.4 1 1 2 3 3 3 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 CBY13593.1 - 0.014 15.2 2.3 0.028 14.3 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 HALZ PF02183.18 CBY13593.1 - 0.035 14.3 0.4 0.035 14.3 0.4 7.4 6 1 0 7 7 7 0 Homeobox associated leucine zipper zf-RING_4 PF14570.6 CBY13593.1 - 0.057 13.2 6.6 0.031 14.1 4.3 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CBY13593.1 - 0.21 11.7 1.2 0.39 10.8 1.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CBY13593.1 - 0.41 10.8 3.8 1.4 9.2 3.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Trans_reg_C PF00486.28 CBY13593.1 - 0.97 9.6 6.1 1.2 9.3 0.2 3.2 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal O-FucT PF10250.9 CBY13594.1 - 0.0088 15.8 5.6 0.46 10.1 5.6 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase GD_AH_C PF04295.13 CBY13594.1 - 0.18 10.5 0.0 0.35 9.6 0.0 1.4 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus AMP-binding PF00501.28 CBY13595.1 - 1.6e-69 234.5 0.0 2.3e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY13595.1 - 4.3e-14 53.2 0.1 9.3e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAP PF00188.26 CBY13596.1 - 0.00014 22.6 0.0 0.00027 21.8 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_transf_49 PF13896.6 CBY13597.1 - 5.6e-89 298.7 0.3 1.2e-88 297.7 0.2 1.6 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan An_peroxidase PF03098.15 CBY13600.1 - 1.1e-46 159.5 0.0 1.5e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase EGF PF00008.27 CBY13600.1 - 9.6 6.6 19.0 5.6 7.4 7.3 2.7 2 0 0 2 2 2 0 EGF-like domain Trypsin PF00089.26 CBY13601.1 - 6.9e-46 156.8 0.8 1e-45 156.3 0.8 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY13601.1 - 1.4e-09 39.0 0.0 2.5e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain cEGF PF12662.7 CBY13601.1 - 7.1e-07 29.0 0.6 7.1e-07 29.0 0.6 2.9 3 0 0 3 3 3 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY13601.1 - 0.00028 21.1 6.0 0.00028 21.1 6.0 3.3 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY13601.1 - 0.1 13.0 14.0 0.084 13.2 1.9 3.4 3 0 0 3 3 3 0 EGF-like domain EGF_3 PF12947.7 CBY13601.1 - 0.28 11.4 12.7 0.51 10.6 1.5 3.3 2 0 0 2 2 2 0 EGF domain EGF_CA PF07645.15 CBY13601.1 - 4.3 7.6 28.2 0.039 14.2 8.8 4.0 3 1 0 3 3 3 0 Calcium-binding EGF domain Sec7 PF01369.20 CBY13603.1 - 7.7e-24 84.4 0.8 9.3e-24 84.1 0.8 1.0 1 0 0 1 1 1 1 Sec7 domain ABC2_membrane PF01061.24 CBY13604.1 - 1.1e-35 123.0 23.4 1.5e-35 122.5 23.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBY13604.1 - 1.5e-20 74.1 0.1 2.5e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CBY13604.1 - 1.4e-05 24.4 13.2 2.2e-05 23.8 11.7 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CBY13604.1 - 0.00015 21.7 0.3 0.00032 20.6 0.3 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CBY13604.1 - 0.0006 19.7 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CBY13604.1 - 0.001 19.1 0.3 0.0027 17.8 0.2 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY13604.1 - 0.0027 18.0 0.1 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY13604.1 - 0.0068 16.8 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBY13604.1 - 0.013 15.3 0.3 0.03 14.1 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 CBY13604.1 - 0.013 15.6 0.5 0.023 14.8 0.5 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 CBY13604.1 - 0.024 15.0 0.0 0.08 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 CBY13604.1 - 0.031 14.3 0.3 0.12 12.4 0.3 1.9 1 1 0 1 1 1 0 Dynamin family PDR_CDR PF06422.12 CBY13604.1 - 0.054 13.4 0.3 0.054 13.4 0.3 2.7 3 0 0 3 3 3 0 CDR ABC transporter Septin PF00735.18 CBY13604.1 - 0.058 12.7 0.1 0.095 12.0 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 CBY13604.1 - 0.065 13.5 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY13604.1 - 0.084 12.6 0.3 0.49 10.1 0.1 2.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CBY13604.1 - 0.086 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CBY13604.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 CBY13604.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Aminotran_1_2 PF00155.21 CBY13605.1 - 2.4e-29 102.6 0.0 3.8e-29 102.0 0.0 1.3 1 1 1 2 2 2 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CBY13605.1 - 1.8e-18 66.6 0.0 2.5e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 CBY13605.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CBY13605.1 - 0.1 11.1 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ion_trans_2 PF07885.16 CBY13606.1 - 1.3e-07 31.5 7.5 2.2e-07 30.7 7.5 1.3 1 0 0 1 1 1 1 Ion channel CDC14 PF08045.11 CBY13606.1 - 0.015 14.4 3.3 0.026 13.6 3.3 1.4 1 0 0 1 1 1 0 Cell division control protein 14, SIN component LPP PF04728.13 CBY13606.1 - 0.026 14.9 0.5 0.026 14.9 0.5 2.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF2985 PF11204.8 CBY13606.1 - 0.032 14.4 0.6 0.08 13.1 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Baculo_p24 PF05073.12 CBY13606.1 - 0.52 10.1 3.8 0.44 10.3 2.1 1.7 1 1 1 2 2 2 0 Baculovirus P24 capsid protein ASD2 PF08687.11 CBY13606.1 - 0.64 9.5 12.1 0.38 10.3 10.0 1.5 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 Sulfotransfer_2 PF03567.14 CBY13607.1 - 7.3e-13 49.0 0.5 3.2e-12 46.9 0.2 1.9 2 0 0 2 2 2 1 Sulfotransferase family Arginosuc_synth PF00764.19 CBY13608.1 - 4.2e-153 510.2 0.0 5.4e-153 509.9 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase HCO3_cotransp PF00955.21 CBY13608.1 - 5.8e-140 467.5 7.0 5.7e-139 464.2 7.0 2.0 1 1 0 1 1 1 1 HCO3- transporter family Xan_ur_permease PF00860.20 CBY13608.1 - 8.6e-05 21.4 2.2 8.6e-05 21.4 2.2 2.7 3 1 0 3 3 3 1 Permease family QueC PF06508.13 CBY13608.1 - 0.008 15.7 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CBY13608.1 - 0.034 12.9 0.1 0.051 12.4 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Guanylate_cyc PF00211.20 CBY13610.1 - 3.5e-62 209.3 0.0 7e-62 208.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CBY13610.1 - 4.5e-38 131.0 0.0 6.7e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY13610.1 - 5.9e-33 114.3 0.0 8.4e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CBY13610.1 - 0.041 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Heme NO binding associated Kinase-like PF14531.6 CBY13610.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like VWA PF00092.28 CBY13611.1 - 7.4e-18 65.4 0.2 9.5e-18 65.0 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 CBY13611.1 - 2.3e-08 34.1 3.7 2.3e-08 34.1 3.7 3.4 3 1 0 3 3 3 1 Thrombospondin type 1 domain RRM_Rrp7 PF17799.1 CBY13612.1 - 0.011 15.5 0.2 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain COA2 PF17051.5 CBY13612.1 - 0.042 13.9 0.6 0.072 13.1 0.6 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 Pkinase PF00069.25 CBY13614.1 - 5.4e-19 68.6 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13614.1 - 6.8e-18 64.9 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Arf PF00025.21 CBY13616.1 - 8.3e-62 207.7 0.0 9.3e-62 207.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBY13616.1 - 4.2e-10 39.3 0.0 2.3e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY13616.1 - 2e-09 37.1 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CBY13616.1 - 9.2e-09 35.6 0.0 2e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBY13616.1 - 1.6e-07 31.4 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CBY13616.1 - 2.4e-07 30.5 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBY13616.1 - 5.1e-06 26.0 0.0 6.6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY13616.1 - 0.00056 19.5 0.1 0.016 14.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CBY13616.1 - 0.026 14.3 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CBY13616.1 - 0.06 12.9 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HCNGP PF07818.13 CBY13617.1 - 2.7e-24 85.6 1.3 2.7e-24 85.6 1.3 1.5 2 0 0 2 2 2 1 HCNGP-like protein RasGEF PF00617.19 CBY13618.1 - 2.4e-47 161.4 2.7 2.5e-47 161.4 0.4 2.2 2 0 0 2 2 2 1 RasGEF domain PDZ_6 PF17820.1 CBY13618.1 - 1.2e-09 37.9 0.0 5.5e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CBY13618.1 - 3.1e-09 37.0 0.0 6.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain cNMP_binding PF00027.29 CBY13618.1 - 5e-09 36.1 0.0 0.00014 21.9 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RA PF00788.23 CBY13618.1 - 1.6e-06 28.7 0.0 5.6e-06 26.9 0.1 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.6 CBY13618.1 - 9e-06 25.9 0.0 2.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RasGEF_N PF00618.20 CBY13618.1 - 2.1e-05 24.7 7.8 0.00011 22.4 3.8 3.2 2 1 0 2 2 2 1 RasGEF N-terminal motif Ufm1 PF03671.14 CBY13618.1 - 0.016 15.2 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin fold modifier 1 protein VapB_antitoxin PF09957.9 CBY13618.1 - 0.073 13.0 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB Kelch_6 PF13964.6 CBY13619.1 - 1.8e-05 24.8 0.1 1.3 9.5 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CBY13619.1 - 0.0015 18.4 0.3 1.2 9.2 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CBY13619.1 - 0.022 14.8 3.2 0.17 11.9 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY13619.1 - 0.053 13.5 1.6 6.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain XhlA PF10779.9 CBY13620.1 - 0.048 13.9 2.9 0.048 13.9 2.9 2.9 2 0 0 2 2 2 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 CBY13620.1 - 0.13 12.3 5.7 2.3 8.2 3.6 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1465 PF07323.12 CBY13620.1 - 0.25 11.2 3.9 0.2 11.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) PIN_2 PF10130.9 CBY13620.1 - 0.52 10.5 7.5 0.45 10.8 0.4 2.7 2 1 0 2 2 2 0 PIN domain FliD_C PF07195.12 CBY13620.1 - 0.6 9.5 12.2 5.9 6.2 12.2 2.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FlxA PF14282.6 CBY13620.1 - 0.61 10.1 10.7 0.75 9.8 7.8 2.4 1 1 1 2 2 2 0 FlxA-like protein PTPS PF01242.19 CBY13620.1 - 0.88 9.6 3.8 3.2 7.7 2.1 2.8 1 1 1 2 2 2 0 6-pyruvoyl tetrahydropterin synthase DUF1366 PF07104.11 CBY13620.1 - 1.1 8.9 10.0 7 6.4 3.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1366) Phasin PF05597.11 CBY13620.1 - 3.2 7.8 7.6 1.5 8.8 1.2 2.7 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MULE PF10551.9 CBY13621.1 - 0.0003 21.2 0.1 0.00091 19.6 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain TatD_DNase PF01026.21 CBY13623.1 - 5.7e-32 111.1 0.0 1.1e-17 64.3 0.0 2.0 1 1 1 2 2 2 2 TatD related DNase Shisa PF13908.6 CBY13624.1 - 0.00019 21.8 0.5 0.0002 21.7 0.5 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LYRIC PF15686.5 CBY13624.1 - 0.00042 20.0 0.1 0.00044 19.9 0.1 1.0 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Orthoreo_P10 PF07204.11 CBY13624.1 - 0.0014 18.6 0.6 0.0014 18.5 0.6 1.1 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 TMEM52 PF14979.6 CBY13624.1 - 0.0014 18.6 2.4 0.0016 18.4 2.4 1.1 1 0 0 1 1 1 1 Transmembrane 52 EphA2_TM PF14575.6 CBY13624.1 - 0.0017 19.2 0.1 0.0018 19.1 0.1 1.1 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain LSR PF05624.14 CBY13624.1 - 0.0049 16.8 9.8 0.0065 16.4 9.8 1.1 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) Rhabdo_glycop PF00974.18 CBY13624.1 - 0.039 12.4 0.8 0.047 12.1 0.8 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein SieB PF14163.6 CBY13624.1 - 0.046 13.2 0.0 0.054 13.0 0.0 1.0 1 0 0 1 1 1 0 Super-infection exclusion protein B MLANA PF14991.6 CBY13624.1 - 0.057 13.7 0.1 0.058 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein melan-A TMEM51 PF15345.6 CBY13624.1 - 0.11 12.3 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 LRR19-TM PF15176.6 CBY13624.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4713 PF15831.5 CBY13624.1 - 1.9 9.0 10.3 2 8.9 7.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Septin PF00735.18 CBY13625.1 - 7.7e-43 146.8 0.0 9.2e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CBY13625.1 - 6e-07 29.5 0.0 7.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY13625.1 - 7.8e-06 25.9 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 CBY13625.1 - 2.3e-05 23.8 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CBY13625.1 - 0.00031 20.8 0.6 0.37 10.8 0.0 2.2 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 CBY13625.1 - 0.0028 17.3 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.6 CBY13625.1 - 0.0062 16.9 0.0 0.0081 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY13625.1 - 0.013 15.8 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CBY13625.1 - 0.017 15.4 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CBY13625.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CBY13625.1 - 0.029 14.9 0.4 0.058 13.9 0.4 1.4 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 CBY13625.1 - 0.03 13.7 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CBY13625.1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B NB-ARC PF00931.22 CBY13625.1 - 0.038 13.2 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 CBY13625.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 CBY13625.1 - 0.12 11.5 0.1 5.3 6.1 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit SKA1 PF07160.12 CBY13626.1 - 0.0037 17.1 3.1 0.0037 17.1 3.1 2.3 1 1 0 2 2 2 1 Spindle and kinetochore-associated protein 1 CCDC92 PF14916.6 CBY13626.1 - 0.017 14.8 1.7 0.017 14.8 1.7 3.6 3 1 0 4 4 4 0 Coiled-coil domain of unknown function GAS PF13851.6 CBY13626.1 - 0.093 12.1 29.9 0.025 14.0 5.7 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CHASE6_C PF17150.4 CBY13626.1 - 3.5 8.4 5.8 4.8 7.9 0.8 3.2 2 2 1 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain MAD PF05557.13 CBY13626.1 - 6 5.1 37.1 0.62 8.4 10.2 2.8 1 1 2 3 3 3 0 Mitotic checkpoint protein ZapB PF06005.12 CBY13626.1 - 8.8 6.8 34.0 1.2 9.7 1.0 4.3 4 1 1 5 5 5 0 Cell division protein ZapB IBN_N PF03810.19 CBY13628.1 - 6.6e-16 58.0 0.6 1.2e-13 50.8 0.0 3.3 3 0 0 3 3 3 2 Importin-beta N-terminal domain DUF3385 PF11865.8 CBY13628.1 - 0.27 11.1 2.8 1.5 8.7 0.1 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF3385) Beta-Casp PF10996.8 CBY13629.1 - 1.2e-28 99.5 0.0 5.2e-28 97.5 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CBY13629.1 - 6.3e-22 78.0 0.0 1.7e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CBY13629.1 - 4.5e-16 58.5 0.0 9.5e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CBY13629.1 - 4.6e-12 46.4 0.3 1.3e-08 35.1 0.1 2.5 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY13629.1 - 7e-09 35.5 0.2 4.8e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CBY13629.1 - 1.4e-05 24.4 0.2 6.9e-05 22.2 0.0 2.1 2 1 0 2 2 2 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 CBY13629.1 - 0.0002 21.3 0.0 0.00075 19.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 CBY13629.1 - 0.081 12.0 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II TPR_14 PF13428.6 CBY13630.1 - 0.089 13.7 0.1 11 7.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MutS_V PF00488.21 CBY13632.1 - 1.7e-73 246.7 0.1 3.7e-73 245.6 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CBY13632.1 - 3.8e-19 69.7 0.9 9.9e-19 68.3 0.9 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CBY13632.1 - 1.7e-07 31.5 0.0 4.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 CBY13632.1 - 6.8e-06 26.3 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CBY13632.1 - 0.00052 20.3 0.1 0.0021 18.3 0.1 2.1 2 0 0 2 2 2 1 MutS domain II VCH_CASS14 PF18315.1 CBY13632.1 - 0.021 14.8 0.3 0.059 13.4 0.3 1.8 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Hce2 PF14856.6 CBY13632.1 - 0.18 12.1 0.1 0.82 10.0 0.0 2.1 2 0 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor F-box-like PF12937.7 CBY13633.1 - 2e-10 40.4 0.8 3.8e-10 39.5 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CBY13633.1 - 1.8e-06 27.6 0.6 1.8e-06 27.6 0.6 1.6 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CBY13633.1 - 8.6e-05 22.4 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 F-box Elongin_A PF06881.11 CBY13633.1 - 0.071 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Glyco_transf_21 PF13506.6 CBY13633.1 - 0.21 11.1 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 WD40 PF00400.32 CBY13634.1 - 6.2e-10 39.5 2.7 8.6e-05 23.2 0.3 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY13634.1 - 6.1e-06 26.4 0.1 0.027 14.8 0.1 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY13634.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CBY13635.1 - 3.1e-05 24.7 3.5 1.5 9.8 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1761 PF08570.10 CBY13635.1 - 0.036 14.3 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) DUF2207 PF09972.9 CBY13635.1 - 0.13 11.0 0.8 0.26 10.0 0.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rap_GAP PF02145.15 CBY13636.1 - 4.2e-40 137.3 0.1 2.2e-39 134.9 0.0 2.1 2 0 0 2 2 2 1 Rap/ran-GAP C2 PF00168.30 CBY13637.1 - 1.5e-48 163.3 0.8 6.3e-27 93.9 0.3 3.5 3 0 0 3 3 3 3 C2 domain Membr_traf_MHD PF10540.9 CBY13637.1 - 5.2e-35 120.8 0.1 1.2e-34 119.6 0.1 1.7 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.17 CBY13637.1 - 2e-21 76.3 0.2 1.2e-20 73.8 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 CBY13637.1 - 2.5e-11 43.3 6.8 7.1e-11 41.8 6.8 1.9 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SRP1_TIP1 PF00660.17 CBY13637.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Seripauperin and TIP1 family SAP30_Sin3_bdg PF13867.6 CBY13637.1 - 0.11 12.9 0.2 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 PTPLA PF04387.14 CBY13638.1 - 6.6e-59 198.3 11.3 8.1e-59 198.0 11.3 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA ANAPC4_WD40 PF12894.7 CBY13639.1 - 0.016 15.5 0.0 0.39 11.1 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY13639.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain TK PF00265.18 CBY13640.1 - 2.4e-60 203.4 0.1 2.7e-60 203.2 0.1 1.0 1 0 0 1 1 1 1 Thymidine kinase ATPase_2 PF01637.18 CBY13640.1 - 0.0046 16.9 0.0 0.0057 16.6 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF3785 PF12653.7 CBY13640.1 - 0.0067 16.5 0.3 0.021 14.9 0.0 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3785) AAA_14 PF13173.6 CBY13640.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain HNH_5 PF14279.6 CBY13640.1 - 0.016 15.1 0.3 0.027 14.3 0.3 1.4 1 0 0 1 1 1 0 HNH endonuclease DUF2064 PF09837.9 CBY13640.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) DEAD PF00270.29 CBY13641.1 - 2.9e-38 131.4 0.0 5.1e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY13641.1 - 3.1e-23 82.2 0.0 1e-21 77.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY13641.1 - 0.001 19.1 2.1 0.001 19.1 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Sulfotransfer_1 PF00685.27 CBY13642.1 - 0.00033 20.2 0.5 0.28 10.6 0.0 3.0 2 1 1 3 3 3 2 Sulfotransferase domain MRVI1 PF05781.12 CBY13642.1 - 0.083 11.6 0.1 0.09 11.5 0.1 1.1 1 0 0 1 1 1 0 MRVI1 protein Tetraspanin PF00335.20 CBY13643.1 - 5.4e-28 98.3 2.1 5.8e-28 98.2 2.1 1.0 1 0 0 1 1 1 1 Tetraspanin family Toxin_10 PF05431.11 CBY13643.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 DUF4876 PF16215.5 CBY13643.1 - 0.085 12.8 0.7 0.12 12.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4876) Pox_A14 PF05767.12 CBY13643.1 - 0.17 12.1 3.9 9.4 6.5 0.8 2.7 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Fz PF01392.22 CBY13644.1 - 2.4e-22 79.7 1.1 5.1e-22 78.6 1.1 1.6 1 0 0 1 1 1 1 Fz domain Conotoxin PF02950.17 CBY13644.1 - 0.055 14.5 0.2 13 6.8 0.0 2.8 2 0 0 2 2 2 0 Conotoxin NTR PF01759.21 CBY13644.1 - 0.17 11.7 2.0 0.4 10.5 2.0 1.7 1 1 0 1 1 1 0 UNC-6/NTR/C345C module IBR PF01485.21 CBY13645.1 - 0.026 14.7 5.8 0.043 14.0 5.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ComX PF05952.12 CBY13645.1 - 0.086 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacillus competence pheromone ComX FYVE_2 PF02318.16 CBY13645.1 - 0.21 11.8 8.6 0.8 9.9 0.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-NADH-PPase PF09297.11 CBY13645.1 - 0.26 11.0 0.6 0.26 11.0 0.6 3.3 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain RecR PF02132.15 CBY13645.1 - 1.6 8.4 7.3 1.6 8.3 0.2 2.7 2 1 0 2 2 2 0 RecR protein LMBR1 PF04791.16 CBY13646.1 - 4.1e-18 65.6 10.2 4.1e-18 65.6 10.2 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein PDEase_I PF00233.19 CBY13647.1 - 1e-80 270.9 3.7 1.5e-80 270.3 3.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MMR_HSR1 PF01926.23 CBY13648.1 - 9e-06 25.7 0.0 6.1e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 CBY13648.1 - 0.0018 17.9 0.0 0.61 9.6 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CBY13648.1 - 0.0035 17.9 0.0 0.009 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY13648.1 - 0.0036 17.7 0.0 0.0058 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 CBY13648.1 - 0.006 15.6 0.1 1.6 7.6 0.0 2.2 1 1 1 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 CBY13648.1 - 0.0067 15.9 0.0 0.27 10.7 0.0 2.3 2 1 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 CBY13648.1 - 0.0074 15.8 0.1 0.046 13.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBY13648.1 - 0.0081 15.7 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY13648.1 - 0.0099 15.8 0.1 0.056 13.3 0.1 1.9 1 1 0 1 1 1 1 RsgA GTPase MCM PF00493.23 CBY13648.1 - 0.017 14.3 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 CBY13648.1 - 0.081 12.7 0.0 0.61 9.9 0.0 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CBY13648.1 - 0.089 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CBY13648.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein KTI12 PF08433.10 CBY13648.1 - 0.14 11.5 0.0 0.66 9.4 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Glyco_hydro_31 PF01055.26 CBY13650.1 - 4.8e-123 411.6 12.6 1.5e-97 327.6 6.4 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CBY13650.1 - 8.3e-12 45.3 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 CBY13650.1 - 6.2e-07 29.2 0.2 1.1e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 CBY13650.1 - 6.3e-05 23.2 0.8 0.00015 22.1 0.8 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 CBY13650.1 - 0.15 12.3 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Glyco_hydro_31 PF01055.26 CBY13651.1 - 3.4e-30 105.6 0.0 5.5e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CBY13651.1 - 3.5e-22 78.8 0.2 6.4e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 CBY13651.1 - 4.7e-10 39.2 1.0 8.5e-10 38.4 1.0 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain Cytochrom_C PF00034.21 CBY13652.1 - 1e-10 42.6 0.1 1.6e-10 42.0 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CBY13652.1 - 5.4e-06 26.6 0.5 2.9e-05 24.3 0.5 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CBY13652.1 - 0.00064 19.4 0.3 0.0014 18.3 0.2 1.6 2 0 0 2 2 2 1 Cytochrome c-550 domain BTB PF00651.31 CBY13653.1 - 7.9e-30 103.3 0.3 4.5e-28 97.7 0.0 2.9 3 1 1 4 4 4 1 BTB/POZ domain BACK PF07707.15 CBY13653.1 - 8.7e-14 51.5 0.9 1.4e-13 50.8 0.3 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Peptidase_C47 PF05543.13 CBY13653.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Staphopain peptidase C47 HTH_ABP1_N PF18107.1 CBY13653.1 - 0.63 9.8 2.4 0.63 9.8 0.3 2.1 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain PTR2 PF00854.21 CBY13654.1 - 0.08 11.8 0.1 0.1 11.4 0.1 1.0 1 0 0 1 1 1 0 POT family Imm6 PF14434.6 CBY13655.1 - 0.041 13.8 0.4 0.099 12.6 0.4 1.6 1 0 0 1 1 1 0 Immunity protein Imm6 EKAL PF17986.1 CBY13655.1 - 0.1 12.6 0.4 0.3 11.1 0.4 1.8 1 0 0 1 1 1 0 EMP3-KAHRP-like N-terminal domain DUF3592 PF12158.8 CBY13655.1 - 0.13 12.3 0.6 0.25 11.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Csm1_N PF18504.1 CBY13655.1 - 0.16 12.3 2.1 0.45 10.9 1.3 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain vMSA PF00695.19 CBY13656.1 - 0.18 10.9 3.2 0.26 10.3 3.2 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF3558 PF12079.8 CBY13656.1 - 0.85 9.6 13.6 1.9 8.5 13.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Dicty_REP PF05086.12 CBY13656.1 - 5 5.0 6.7 6.3 4.6 6.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 CBY13656.1 - 9.1 6.3 30.4 19 5.2 30.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein F5_F8_type_C PF00754.25 CBY13657.1 - 0.0019 18.3 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Filament PF00038.21 CBY13658.1 - 9.3e-06 25.4 2.4 1.5e-05 24.7 2.4 1.4 1 0 0 1 1 1 1 Intermediate filament protein DUF2150 PF09920.9 CBY13658.1 - 0.02 14.8 0.3 0.036 14.1 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) CdvA PF18822.1 CBY13658.1 - 0.024 14.5 3.7 0.66 9.8 0.7 2.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF1640 PF07798.11 CBY13658.1 - 0.044 13.8 8.2 0.18 11.8 8.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.12 CBY13658.1 - 0.1 12.7 10.0 0.052 13.6 6.6 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cor1 PF04803.12 CBY13658.1 - 0.15 12.3 6.0 0.36 11.0 6.0 1.8 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region DUF5595 PF18077.1 CBY13658.1 - 0.18 11.9 4.4 4.2 7.5 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) DivIC PF04977.15 CBY13658.1 - 0.2 11.5 7.9 0.19 11.5 0.9 3.3 4 0 0 4 4 4 0 Septum formation initiator DUF2205 PF10224.9 CBY13658.1 - 0.26 11.3 5.2 3.3 7.8 0.0 3.1 1 1 3 4 4 4 0 Short coiled-coil protein Prominin PF05478.11 CBY13658.1 - 0.37 8.7 5.3 3.3 5.6 4.9 1.7 1 1 0 1 1 1 0 Prominin ZapB PF06005.12 CBY13658.1 - 0.37 11.3 7.5 1.8 9.1 0.5 2.6 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 CBY13658.1 - 0.93 10.2 5.1 1.1 9.9 0.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Fungal_TACC PF12709.7 CBY13658.1 - 1.4 9.4 5.4 4.8 7.7 0.4 3.1 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins FlaC_arch PF05377.11 CBY13658.1 - 2.9 8.4 10.7 1.7 9.1 0.1 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Gelsolin PF00626.22 CBY13659.1 - 1e-77 256.0 0.0 2.1e-18 66.0 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 CBY13659.1 - 2.8e-15 56.1 1.1 5.9e-15 55.0 1.1 1.6 1 0 0 1 1 1 1 Villin headpiece domain MutS_V PF00488.21 CBY13661.1 - 3.8e-11 43.3 0.1 8.1e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CBY13661.1 - 0.00012 22.3 1.3 0.00036 20.8 0.2 2.3 2 0 0 2 2 2 1 MutS domain III AAA_16 PF13191.6 CBY13661.1 - 0.078 13.4 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_C2 PF00648.21 CBY13662.1 - 1.5e-72 244.1 0.1 2.1e-72 243.6 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Ank_2 PF12796.7 CBY13663.1 - 1.4e-05 25.6 0.6 0.095 13.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY13663.1 - 8.3e-05 23.1 0.3 5.8 7.6 0.0 4.6 1 1 4 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY13663.1 - 0.0002 21.6 0.4 0.043 14.1 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY13663.1 - 0.011 16.1 0.3 7.6 7.2 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Vps39_1 PF10366.9 CBY13663.1 - 0.11 12.8 0.6 28 5.0 0.0 3.1 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Trypan_PARP PF05887.11 CBY13663.1 - 2.2 8.3 15.7 0.59 10.1 7.0 2.9 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Med3 PF11593.8 CBY13664.1 - 1.5 7.9 32.7 2 7.5 32.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sprouty PF05210.13 CBY13665.1 - 5.2e-16 58.9 16.2 8e-16 58.3 16.2 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) Mucin PF01456.17 CBY13667.1 - 0.00057 19.9 21.0 0.0011 19.0 21.0 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SLC12 PF03522.15 CBY13667.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Solute carrier family 12 Kelch_6 PF13964.6 CBY13667.1 - 0.036 14.4 1.0 0.58 10.5 0.0 3.4 5 0 0 5 5 5 0 Kelch motif Dicty_REP PF05086.12 CBY13667.1 - 0.069 11.1 3.2 0.083 10.9 3.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Kelch_2 PF07646.15 CBY13667.1 - 0.12 12.4 1.1 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 Kelch motif MGC-24 PF05283.11 CBY13667.1 - 2.7 8.4 13.3 6.3 7.3 13.3 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Kelch_6 PF13964.6 CBY13668.1 - 0.029 14.7 4.1 0.17 12.2 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 CBY13668.1 - 0.048 13.7 0.3 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY13668.1 - 0.21 11.6 2.0 0.89 9.6 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Phospholip_A2_1 PF00068.19 CBY13670.1 - 4.1e-14 53.0 11.6 4.1e-14 53.0 11.6 2.4 2 2 0 2 2 2 1 Phospholipase A2 Sulfotransfer_4 PF17784.1 CBY13671.1 - 4.2e-21 75.8 0.1 5.4e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Phospholip_A2_1 PF00068.19 CBY13672.1 - 7.2e-16 58.7 7.9 1.3e-15 57.9 7.9 1.4 1 0 0 1 1 1 1 Phospholipase A2 EB PF01683.18 CBY13672.1 - 7.2 7.0 14.5 0.26 11.6 2.8 2.5 1 1 0 2 2 2 0 EB module Kelch_6 PF13964.6 CBY13673.1 - 0.018 15.3 0.4 0.34 11.3 0.0 3.0 3 1 1 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CBY13673.1 - 0.1 12.6 0.1 1.1 9.4 0.0 2.5 3 0 0 3 3 3 0 Kelch motif Mucin PF01456.17 CBY13674.1 - 0.00015 21.7 15.3 0.00033 20.7 15.3 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Phospholip_A2_1 PF00068.19 CBY13675.1 - 4.1e-14 53.0 11.6 4.1e-14 53.0 11.6 2.4 2 2 0 2 2 2 1 Phospholipase A2 Sulfotransfer_4 PF17784.1 CBY13677.1 - 4.7e-45 154.1 0.3 7e-45 153.5 0.3 1.3 1 0 0 1 1 1 1 Sulfotransferase domain GAF_2 PF13185.6 CBY13678.1 - 3.1e-06 27.5 0.0 3.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CBY13678.1 - 0.022 15.4 0.0 0.025 15.2 0.0 1.3 1 0 0 1 1 1 0 GAF domain Hydrolase_4 PF12146.8 CBY13679.1 - 7.8e-13 48.2 0.0 9.4e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY13679.1 - 4.3e-10 39.7 0.0 5.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY13679.1 - 3.4e-07 31.1 0.1 4.1e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CBY13679.1 - 3.7e-05 23.5 0.0 5.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.12 CBY13679.1 - 0.0088 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.13 CBY13679.1 - 0.016 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 CBY13679.1 - 0.098 12.4 0.3 0.5 10.1 0.3 1.9 1 1 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 CBY13679.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Mt_ATP-synt_B PF05405.14 CBY13680.1 - 3.7e-09 36.4 3.0 3.9e-09 36.3 3.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PWI PF01480.17 CBY13680.1 - 0.073 13.4 2.1 0.12 12.7 0.7 1.8 1 1 1 2 2 2 0 PWI domain Thioredoxin_8 PF13905.6 CBY13682.1 - 0.01 16.2 0.1 0.011 16.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like CUB PF00431.20 CBY13684.1 - 0.0028 18.0 0.0 0.0049 17.2 0.0 1.4 1 0 0 1 1 1 1 CUB domain Phage_base_V PF04717.12 CBY13685.1 - 0.049 13.6 0.2 0.39 10.6 0.1 1.9 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector EF-hand_1 PF00036.32 CBY13687.1 - 5.2e-09 35.0 0.5 0.0024 17.3 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY13687.1 - 5.4e-09 35.3 2.8 0.003 17.4 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY13687.1 - 1e-08 35.5 0.6 0.0017 18.7 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CBY13687.1 - 0.0019 18.5 0.0 2.8 8.3 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY13687.1 - 0.0041 16.6 1.0 0.26 10.9 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CBY13687.1 - 0.09 12.6 3.7 4.5 7.2 0.2 3.9 3 2 0 3 3 3 0 EF-hand domain pair DUF3080 PF11279.8 CBY13687.1 - 0.24 10.6 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) DDE_Tnp_2 PF04693.12 CBY13689.1 - 0.12 11.6 0.1 0.13 11.5 0.1 1.0 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 Calsequestrin PF01216.17 CBY13690.1 - 5.6e-109 364.7 10.8 5.6e-109 364.7 10.8 2.0 1 1 1 2 2 2 1 Calsequestrin Thioredoxin_6 PF13848.6 CBY13690.1 - 4.6e-14 52.7 4.6 3.1e-13 50.1 0.3 2.8 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 CBY13690.1 - 0.02 14.9 0.0 1 9.3 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin Kin17_mid PF10357.9 CBY13690.1 - 0.2 11.6 0.8 3 7.8 0.3 2.6 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein TFIIA PF03153.13 CBY13690.1 - 3.8 7.4 20.0 4.4 7.2 20.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FXa_inhibition PF14670.6 CBY13691.1 - 6.1e-06 26.4 12.6 4.1e-05 23.8 12.6 2.4 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Zona_pellucida PF00100.23 CBY13692.1 - 4.4e-09 36.5 0.6 5.4e-09 36.2 0.6 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Aldedh PF00171.22 CBY13693.1 - 1.3e-34 119.5 0.0 1.6e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Trypsin PF00089.26 CBY13694.1 - 4.1e-49 167.4 0.9 5.5e-49 167.0 0.9 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY13694.1 - 9.2e-05 23.4 0.0 0.00021 22.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY13694.1 - 0.0017 18.7 0.1 0.0097 16.3 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Elf1 PF05129.13 CBY13695.1 - 0.099 12.7 7.0 0.22 11.6 0.5 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Carb_anhydrase PF00194.21 CBY13697.1 - 2.7e-65 220.4 0.1 3.6e-65 220.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1993 PF09351.10 CBY13697.1 - 0.07 13.3 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Elf1 PF05129.13 CBY13698.1 - 0.24 11.5 2.9 0.18 11.8 0.6 2.1 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Carb_anhydrase PF00194.21 CBY13701.1 - 6.1e-63 212.7 0.1 8.1e-63 212.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 CBY13702.1 - 0.005 16.4 0.1 0.0055 16.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 CBY13703.1 - 1.7e-54 185.1 0.2 2.2e-54 184.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase YDG PF18657.1 CBY13703.1 - 0.12 12.6 0.8 0.47 10.7 0.1 2.4 3 0 0 3 3 3 0 YDG domain Dimer_Tnp_hAT PF05699.14 CBY13704.1 - 0.0019 18.0 0.2 0.003 17.3 0.2 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCCH_8 PF18633.1 CBY13705.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 DUF489 PF04356.12 CBY13705.1 - 0.066 13.2 0.5 0.17 11.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF4164 PF13747.6 CBY13705.1 - 0.39 11.0 2.8 3.2 8.1 2.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) XhlA PF10779.9 CBY13705.1 - 0.49 10.6 4.5 6.6 7.0 0.7 2.7 2 0 0 2 2 2 0 Haemolysin XhlA FlxA PF14282.6 CBY13705.1 - 6 6.9 8.6 1.6 8.8 1.8 3.1 2 1 1 3 3 3 0 FlxA-like protein Peptidase_M90 PF06167.12 CBY13706.1 - 5.1e-05 23.0 3.6 0.013 15.1 3.6 2.2 1 1 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 Peptidase_M91 PF14891.6 CBY13706.1 - 0.01 16.2 0.0 0.013 15.8 0.0 1.1 1 0 0 1 1 1 1 Effector protein F-box PF00646.33 CBY13708.1 - 7.8e-05 22.4 0.1 0.002 18.0 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CBY13708.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like IBR PF01485.21 CBY13708.1 - 0.018 15.2 7.2 0.051 13.8 7.2 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF3797 PF12677.7 CBY13708.1 - 0.043 13.7 2.2 0.12 12.2 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) CEBP_ZZ PF16366.5 CBY13708.1 - 0.6 10.4 7.5 1.5 9.1 7.5 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Trypsin PF00089.26 CBY13710.1 - 9.2e-21 74.7 0.1 7.4e-20 71.7 0.1 2.1 1 1 1 2 2 2 1 Trypsin CS PF04969.16 CBY13712.1 - 0.011 16.7 0.4 0.016 16.2 0.1 1.4 2 0 0 2 2 2 0 CS domain Nucleos_tra2_C PF07662.13 CBY13714.1 - 1.2e-64 218.0 5.0 3e-64 216.7 5.0 1.7 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CBY13714.1 - 1.3e-19 70.6 4.6 1.3e-19 70.6 4.6 3.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CBY13714.1 - 0.00015 22.0 5.6 0.00015 22.0 5.6 3.2 5 0 0 5 5 5 1 Nucleoside recognition DUF5102 PF17104.5 CBY13715.1 - 0.13 12.3 9.6 0.14 12.2 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) BDHCT_assoc PF16204.5 CBY13715.1 - 0.26 11.0 7.2 0.31 10.7 7.2 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein DUF2457 PF10446.9 CBY13715.1 - 2.9 6.9 7.8 3 6.9 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 CBY13715.1 - 6.3 6.8 6.5 6.9 6.7 6.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Trypsin PF00089.26 CBY13717.1 - 1e-45 156.3 0.1 2.1e-45 155.2 0.1 1.5 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CBY13718.1 - 1.2e-11 44.8 0.1 2e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Trypsin OLF PF02191.16 CBY13719.1 - 9.1e-66 221.9 5.6 2.1e-65 220.7 5.6 1.6 1 0 0 1 1 1 1 Olfactomedin-like domain TrkH PF02386.16 CBY13719.1 - 4.3 5.7 15.9 7.5 4.9 15.9 1.3 1 0 0 1 1 1 0 Cation transport protein TSP_1 PF00090.19 CBY13720.1 - 8.2e-09 35.5 22.4 2.3e-05 24.5 8.1 4.7 5 2 0 5 5 5 3 Thrombospondin type 1 domain DUF1870 PF08965.10 CBY13720.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1870) CCDC53 PF10152.9 CBY13721.1 - 0.024 15.1 4.5 0.036 14.5 4.5 1.4 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3533 PF12051.8 CBY13721.1 - 3.9 6.3 6.0 4.9 6.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Peptidase_M49 PF03571.15 CBY13723.1 - 0.00097 17.6 1.3 0.0013 17.2 1.3 1.1 1 0 0 1 1 1 1 Peptidase family M49 Plasmodium_Vir PF05795.11 CBY13723.1 - 0.013 14.9 7.2 0.017 14.5 7.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GREB1 PF15782.5 CBY13723.1 - 0.095 9.8 5.0 0.099 9.8 5.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CBY13723.1 - 0.87 8.1 5.4 1 7.8 5.4 1.0 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 CBY13723.1 - 4.1 5.9 17.5 5 5.7 17.5 1.0 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 CBY13723.1 - 5.6 6.6 9.8 6.9 6.3 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PAP1 PF08601.10 CBY13723.1 - 6.3 6.4 17.3 8.3 6.0 17.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RIFIN PF02009.16 CBY13723.1 - 9.7 6.0 13.3 14 5.5 13.3 1.3 1 0 0 1 1 1 0 Rifin GFO_IDH_MocA PF01408.22 CBY13724.1 - 4.2e-25 88.9 0.0 9.6e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CBY13724.1 - 4.2e-08 33.2 0.0 9.4e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 CBY13724.1 - 2.7e-05 24.8 0.0 5.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CBY13724.1 - 0.00085 19.9 0.0 0.0028 18.2 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 CBY13724.1 - 0.0036 17.7 0.0 0.016 15.6 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 CBY13724.1 - 0.0042 17.4 0.0 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CBY13724.1 - 0.065 13.5 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CBY13724.1 - 0.084 13.1 0.1 0.65 10.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain CHGN PF05679.16 CBY13725.1 - 6.7e-72 243.0 2.6 1.7e-59 202.1 0.2 2.1 1 1 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY13725.1 - 1.3e-12 47.7 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 CBY13725.1 - 1.7e-09 37.2 0.3 4.9e-09 35.7 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Galactosyl_T PF01762.21 CBY13725.1 - 5.1e-05 23.2 0.0 0.15 11.8 0.0 3.3 2 1 0 2 2 2 2 Galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY13725.1 - 0.0029 17.1 0.4 0.0082 15.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CRISPR_Cas9_WED PF18061.1 CBY13725.1 - 0.023 14.8 0.7 0.066 13.3 0.7 1.8 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain Glyco_hydro_35 PF01301.19 CBY13726.1 - 2.4e-90 303.4 1.2 3.2e-90 303.0 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY13726.1 - 4.6e-08 32.8 0.2 1e-07 31.6 0.2 1.6 1 1 0 1 1 1 1 Beta-galactosidase Tubulin PF00091.25 CBY13728.1 - 8.4e-67 225.2 0.0 1.1e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY13728.1 - 3.2e-30 104.9 0.0 5.8e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY13728.1 - 0.0018 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Gal_Lectin PF02140.18 CBY13729.1 - 1.1e-16 61.0 0.3 1.7e-16 60.4 0.3 1.3 1 0 0 1 1 1 1 Galactose binding lectin domain Laminin_EGF PF00053.24 CBY13731.1 - 0.022 14.9 16.0 0.047 13.8 16.0 1.5 1 0 0 1 1 1 0 Laminin EGF domain Rop-like PF05082.13 CBY13731.1 - 5 7.0 9.2 6.3 6.7 1.5 4.3 3 1 1 4 4 4 0 Rop-like Glyoxalase_2 PF12681.7 CBY13732.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain LRR_4 PF12799.7 CBY13735.1 - 1.6e-14 53.7 9.5 4.4e-05 23.7 0.1 3.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY13735.1 - 5.3e-13 48.8 5.6 8.4e-06 25.4 2.7 2.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 CBY13735.1 - 3.1e-07 30.1 10.4 0.0072 16.1 0.1 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CBY13735.1 - 0.12 12.5 5.3 8.5 6.7 0.3 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 CBY13735.1 - 0.2 12.3 6.2 87 4.3 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat Mito_carr PF00153.27 CBY13736.1 - 6.4e-39 131.8 0.5 1.2e-20 73.2 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein MFS_1 PF07690.16 CBY13737.1 - 2.4e-11 43.2 5.0 2.7e-11 43.0 5.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY13737.1 - 4.2e-07 29.2 1.6 4.8e-07 29.0 1.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 CBY13737.1 - 5.4e-06 25.5 1.8 6.7e-06 25.2 1.8 1.1 1 0 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 CBY13737.1 - 1.8e-05 23.7 0.4 2e-05 23.5 0.4 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter HLH PF00010.26 CBY13738.1 - 3.6e-12 46.1 0.5 6.1e-12 45.3 0.4 1.5 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 CBY13738.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3754 PF12576.8 CBY13739.1 - 0.077 12.9 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) SVM_signal PF12113.8 CBY13739.1 - 0.57 10.1 3.7 0.28 11.1 0.4 2.2 2 0 0 2 2 2 0 SVM protein signal sequence Tetraspanin PF00335.20 CBY13739.1 - 1.6 8.4 4.8 0.82 9.3 2.8 1.5 2 0 0 2 2 2 0 Tetraspanin family zf-TAZ PF02135.16 CBY13740.1 - 0.017 15.5 15.2 0.043 14.3 15.0 1.7 1 1 1 2 2 2 0 TAZ zinc finger SEN1_N PF12726.7 CBY13740.1 - 1.8 6.7 4.1 2 6.5 4.1 1.0 1 0 0 1 1 1 0 SEN1 N terminal IBR PF01485.21 CBY13740.1 - 6.5 7.1 15.5 3 8.1 5.0 3.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain SRP19 PF01922.17 CBY13743.1 - 5.6e-23 81.7 0.1 6.8e-23 81.4 0.1 1.1 1 0 0 1 1 1 1 SRP19 protein SRP19 PF01922.17 CBY13744.1 - 4.2e-27 94.9 0.3 7.8e-27 94.1 0.0 1.6 2 0 0 2 2 2 1 SRP19 protein WYL_2 PF10902.8 CBY13744.1 - 0.11 12.9 0.2 0.27 11.6 0.2 1.8 1 1 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold Paf1 PF03985.13 CBY13745.1 - 4e-91 306.1 12.2 5.4e-91 305.7 12.2 1.1 1 0 0 1 1 1 1 Paf1 Spt20 PF12090.8 CBY13745.1 - 9.1e-05 22.2 0.3 0.037 13.6 0.1 2.6 2 0 0 2 2 2 2 Spt20 family TPD52 PF04201.15 CBY13746.1 - 1e-12 48.0 0.4 1.1e-12 47.9 0.4 1.0 1 0 0 1 1 1 1 Tumour protein D52 family TRAPP PF04051.16 CBY13746.1 - 0.16 11.7 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component Sulfotransfer_4 PF17784.1 CBY13747.1 - 0.0024 17.8 0.0 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Thioredoxin_8 PF13905.6 CBY13747.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like F-box PF00646.33 CBY13748.1 - 0.00029 20.6 0.3 0.0031 17.4 0.3 2.3 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 CBY13748.1 - 0.00084 19.2 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like DnaJ PF00226.31 CBY13748.1 - 0.0045 17.1 0.1 0.012 15.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 CBY13750.1 - 5.8e-49 166.8 0.0 6.5e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13750.1 - 1.8e-30 106.1 0.0 2e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY13750.1 - 0.03 14.2 0.0 1.8 8.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DnaJ PF00226.31 CBY13751.1 - 2e-08 34.2 0.3 0.0069 16.5 0.0 2.8 1 1 1 2 2 2 2 DnaJ domain F-box PF00646.33 CBY13751.1 - 0.00074 19.3 0.3 0.0061 16.4 0.3 2.3 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 CBY13751.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like RPT PF13446.6 CBY13751.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein F-box PF00646.33 CBY13752.1 - 0.00028 20.7 0.4 0.0065 16.3 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CBY13752.1 - 0.00094 19.0 0.0 0.0016 18.3 0.0 1.4 1 1 0 1 1 1 1 F-box-like DnaJ PF00226.31 CBY13752.1 - 0.13 12.4 0.1 0.58 10.3 0.0 2.1 3 0 0 3 3 3 0 DnaJ domain Pkinase PF00069.25 CBY13753.1 - 1.3e-60 205.0 0.0 1.8e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13753.1 - 1.7e-32 112.7 0.0 2.3e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.9 CBY13753.1 - 0.0031 18.1 0.3 0.0057 17.2 0.3 1.4 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein GCFC PF07842.12 CBY13754.1 - 1.1e-39 136.8 16.7 1.7e-39 136.1 16.7 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 CBY13754.1 - 2.1e-14 53.1 2.7 4.1e-14 52.2 2.7 1.5 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 CBY13754.1 - 7e-10 39.2 3.9 7e-10 39.2 3.9 3.6 2 2 2 4 4 4 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 CBY13754.1 - 2.3e-05 24.4 2.5 2.3e-05 24.4 2.5 2.2 2 0 0 2 2 2 1 G-patch domain Peptidase_C48 PF02902.19 CBY13755.1 - 1.6e-32 113.1 0.2 2.6e-32 112.4 0.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Sulfotransfer_4 PF17784.1 CBY13756.1 - 0.0051 16.7 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain F-box-like PF12937.7 CBY13757.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 CBY13757.1 - 0.0023 17.8 0.4 0.049 13.5 0.1 2.2 2 0 0 2 2 2 1 F-box domain DnaJ PF00226.31 CBY13757.1 - 0.13 12.4 0.1 0.57 10.3 0.0 2.1 3 0 0 3 3 3 0 DnaJ domain Pkinase PF00069.25 CBY13759.1 - 0.0008 18.9 0.0 0.0008 18.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13759.1 - 0.039 13.2 0.0 0.039 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 CBY13761.1 - 1.4e-09 37.7 3.5 6.4e-09 35.6 0.3 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13761.1 - 8.5e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Mucin PF01456.17 CBY13762.1 - 2.5 8.1 23.4 3.3 7.7 23.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Dendrin PF15498.6 CBY13763.1 - 0.0088 14.8 0.7 0.011 14.6 0.7 1.0 1 0 0 1 1 1 1 Nephrin and CD2AP-binding protein, Dendrin ABC_tran PF00005.27 CBY13764.1 - 6.7e-21 75.2 0.0 9e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBY13764.1 - 2.4e-07 30.4 0.0 2.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 CBY13765.1 - 2.5e-62 211.0 11.8 3.7e-62 210.4 11.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBY13765.1 - 1.4e-34 119.5 0.1 6.5e-34 117.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CBY13765.1 - 6.8e-07 28.9 2.1 0.00032 20.2 0.0 2.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY13765.1 - 0.00046 20.1 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 CBY13765.1 - 0.00093 19.0 0.9 0.0047 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CBY13765.1 - 0.0027 17.4 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsX PF02687.21 CBY13765.1 - 0.0063 17.0 2.9 0.0063 17.0 2.9 3.3 3 0 0 3 3 3 1 FtsX-like permease family AAA_23 PF13476.6 CBY13765.1 - 0.0078 16.7 3.0 0.009 16.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CBY13765.1 - 0.011 16.2 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBY13765.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF1659 PF07872.11 CBY13765.1 - 0.058 13.1 0.3 0.37 10.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1659) MtrB PF05440.12 CBY13765.1 - 0.88 10.0 3.5 47 4.5 0.0 3.6 4 0 0 4 4 3 0 Tetrahydromethanopterin S-methyltransferase subunit B UPF0542 PF15086.6 CBY13765.1 - 3.3 7.7 6.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Pkinase PF00069.25 CBY13766.1 - 2.3e-11 43.5 1.1 5.6e-11 42.3 1.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13766.1 - 2.1e-06 27.2 0.1 7.2e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase BRCT PF00533.26 CBY13766.1 - 0.24 11.8 2.6 4.9 7.6 0.2 2.8 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF4816 PF16086.5 CBY13766.1 - 6.3 6.8 7.2 22 5.1 1.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4816) RILP PF11461.8 CBY13770.1 - 1.6e-05 25.0 1.3 1.6e-05 25.0 1.3 2.9 3 0 0 3 3 3 1 Rab interacting lysosomal protein CD20 PF04103.15 CBY13771.1 - 0.044 13.9 8.8 0.9 9.6 0.0 2.6 1 1 0 2 2 2 0 CD20-like family DUF373 PF04123.13 CBY13771.1 - 0.19 11.1 2.1 0.22 10.9 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Tetraspanin PF00335.20 CBY13771.1 - 3.7 7.2 14.4 81 2.8 14.4 2.2 1 1 0 1 1 1 0 Tetraspanin family Viral_Beta_CD PF04530.12 CBY13771.1 - 4 7.8 5.4 1 9.6 0.3 2.6 3 1 1 4 4 4 0 Viral Beta C/D like family Phage_Coat_Gp8 PF05371.12 CBY13773.1 - 0.022 14.5 0.6 0.036 13.8 0.6 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 zf-DNA_Pol PF08996.10 CBY13774.1 - 0.057 13.2 1.0 0.057 13.2 1.0 1.5 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger Zn_ribbon_SprT PF17283.2 CBY13774.1 - 0.68 9.9 10.5 3.3 7.7 7.7 2.7 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Anti-TRAP PF15777.5 CBY13774.1 - 1.7 8.6 6.6 0.35 10.9 0.6 2.3 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn-ribbon_8 PF09723.10 CBY13774.1 - 4.8 7.4 8.9 6.8 6.9 1.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS91 PF14319.6 CBY13774.1 - 8.3 6.5 9.9 0.63 10.1 2.8 2.3 1 1 2 3 3 3 0 Transposase zinc-binding domain ArfGap PF01412.18 CBY13775.1 - 7.6e-36 122.7 6.0 1.5e-35 121.8 0.1 3.6 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf SH3_9 PF14604.6 CBY13775.1 - 1.4e-10 40.8 0.5 3.7e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain Ank_2 PF12796.7 CBY13775.1 - 3.6e-08 33.9 0.1 7.6e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SH3_1 PF00018.28 CBY13775.1 - 2.4e-07 30.3 0.2 6.9e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain BAR_3 PF16746.5 CBY13775.1 - 7.6e-07 29.1 11.6 7.6e-07 29.1 11.6 3.1 2 1 0 2 2 2 1 BAR domain of APPL family Ank_3 PF13606.6 CBY13775.1 - 1.2e-05 25.3 0.6 0.015 15.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CBY13775.1 - 7.5e-05 22.9 0.1 0.00019 21.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY13775.1 - 0.00019 21.7 1.2 0.071 13.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat SH3_2 PF07653.17 CBY13775.1 - 0.0008 19.0 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 CBY13775.1 - 0.0014 19.1 0.4 0.0042 17.6 0.4 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) PH PF00169.29 CBY13775.1 - 0.016 15.7 1.3 0.025 15.1 0.1 2.0 2 0 0 2 2 1 0 PH domain MADF_DNA_bdg PF10545.9 CBY13775.1 - 0.029 14.7 5.2 0.026 14.8 1.8 2.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PRKCSH-like PF12999.7 CBY13775.1 - 2.8 7.7 6.7 3.5 7.4 1.6 2.7 2 0 0 2 2 2 0 Glucosidase II beta subunit-like PH_11 PF15413.6 CBY13775.1 - 9.2 6.7 7.8 1.1 9.7 0.5 3.3 3 1 0 3 3 3 0 Pleckstrin homology domain Mito_carr PF00153.27 CBY13776.1 - 9.5e-62 205.0 4.9 5e-23 80.9 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein BUD22 PF09073.10 CBY13777.1 - 0.37 10.1 5.8 0.72 9.1 5.8 1.4 1 0 0 1 1 1 0 BUD22 SAM_4 PF18017.1 CBY13778.1 - 1.4e-13 50.6 0.0 2.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY13778.1 - 0.096 13.1 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Aldo_ket_red PF00248.21 CBY13779.1 - 3.5e-13 49.4 0.0 3.9e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IQ PF00612.27 CBY13781.1 - 1.7e-06 27.3 1.4 2.7e-06 26.7 1.4 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4598 PF15370.6 CBY13784.1 - 5.9e-08 33.2 5.2 6.3e-08 33.1 2.8 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Toxin-deaminase PF14424.6 CBY13786.1 - 0.0016 18.6 0.6 0.0029 17.7 0.3 1.6 1 1 0 1 1 1 1 The BURPS668_1122 family of deaminases Shikimate_dh_N PF08501.11 CBY13786.1 - 0.095 13.0 2.5 0.21 11.9 2.5 1.6 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain SKA1 PF07160.12 CBY13786.1 - 0.14 12.0 4.3 0.25 11.2 4.3 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Uds1 PF15456.6 CBY13786.1 - 0.23 11.6 5.4 0.43 10.8 5.4 1.4 1 0 0 1 1 1 0 Up-regulated During Septation DUF1664 PF07889.12 CBY13786.1 - 0.23 11.5 9.0 0.71 9.9 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 CBY13786.1 - 0.31 10.8 17.7 0.22 11.3 15.8 1.7 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ISG65-75 PF11727.8 CBY13786.1 - 0.43 9.8 11.0 0.61 9.3 11.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Peptidase_M54 PF07998.11 CBY13786.1 - 0.57 10.1 1.7 14 5.6 0.5 2.3 2 1 0 2 2 2 0 Peptidase family M54 IFT57 PF10498.9 CBY13786.1 - 0.63 9.0 8.7 0.89 8.5 8.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Cytochrom_C_2 PF01322.20 CBY13786.1 - 1.5 9.7 7.8 2.6 9.0 7.8 1.4 1 0 0 1 1 1 0 Cytochrome C' DUF948 PF06103.11 CBY13786.1 - 1.6 9.0 13.3 3.3 8.0 2.2 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 CBY13786.1 - 2.2 7.1 14.5 3.2 6.5 14.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 CBY13786.1 - 4.8 7.5 11.8 1.5 9.2 8.3 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.11 CBY13786.1 - 8.2 6.5 13.5 3 7.9 2.5 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Iso_dh PF00180.20 CBY13788.1 - 3.4e-63 213.9 0.5 3.8e-63 213.7 0.5 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SAP30_Sin3_bdg PF13867.6 CBY13789.1 - 2.5e-19 69.3 0.2 5.3e-19 68.3 0.1 1.6 1 1 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 HpcH_HpaI PF03328.14 CBY13790.1 - 5.8e-46 156.4 0.0 7.6e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CBY13790.1 - 1.8e-10 40.5 0.0 2.3e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Peptidase_A22B PF04258.13 CBY13791.1 - 2.7e-84 283.1 10.2 3.7e-84 282.6 10.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CBY13791.1 - 0.00026 20.6 8.5 0.00026 20.6 8.5 2.4 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 CBY13791.1 - 0.0022 16.9 0.8 0.0022 16.9 0.8 2.5 1 1 1 2 2 2 1 Presenilin DUF1772 PF08592.11 CBY13791.1 - 0.015 15.6 3.9 0.23 11.8 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) CENP-B_dimeris PF09026.10 CBY13791.1 - 0.84 10.1 11.9 0.91 10.0 8.0 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain CytB6-F_Fe-S PF08802.10 CBY13791.1 - 3.2 7.9 7.0 6.7 6.8 0.1 3.2 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Wyosine_form PF08608.12 CBY13792.1 - 2e-28 98.5 0.1 5.2e-28 97.2 0.1 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CBY13792.1 - 2.1e-17 64.0 0.0 5.1e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 CBY13792.1 - 1.1e-05 25.7 0.1 2.6e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin Kelch_1 PF01344.25 CBY13793.1 - 3.8e-34 116.0 6.4 6.1e-08 32.1 0.1 7.0 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 CBY13793.1 - 1.5e-31 107.6 0.3 6.5e-10 38.9 0.1 6.2 3 2 3 6 6 6 3 Kelch motif Kelch_3 PF13415.6 CBY13793.1 - 3.4e-26 91.0 0.0 8.4e-08 32.3 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY13793.1 - 1.8e-25 88.7 0.3 4.6e-07 29.7 0.1 7.1 6 1 1 7 7 7 4 Galactose oxidase, central domain BACK PF07707.15 CBY13793.1 - 1.8e-22 79.4 0.2 5.9e-22 77.7 0.1 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CBY13793.1 - 5.7e-18 64.1 0.8 0.00015 21.6 0.1 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 CBY13793.1 - 6.8e-17 61.7 0.1 2.5e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.6 CBY13793.1 - 2.2e-12 46.7 3.6 0.00013 21.9 0.1 5.8 7 0 0 7 7 7 3 Kelch motif PQQ_3 PF13570.6 CBY13793.1 - 4.2e-05 23.9 0.5 0.2 12.2 0.0 4.3 4 0 0 4 4 4 1 PQQ-like domain Motile_Sperm PF00635.26 CBY13794.1 - 3.9e-14 52.4 0.0 5.2e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain tRNA_m1G_MT PF01746.21 CBY13795.1 - 1.5e-16 60.7 0.0 2.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_S6e PF01092.19 CBY13795.1 - 0.11 12.5 1.6 0.14 12.2 0.5 1.7 2 0 0 2 2 2 0 Ribosomal protein S6e 3-alpha PF03475.14 CBY13795.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 3-alpha domain Vps51 PF08700.11 CBY13796.1 - 5.2e-14 52.1 0.7 5.2e-14 52.1 0.7 3.6 3 0 0 3 3 3 1 Vps51/Vps67 FliD_C PF07195.12 CBY13796.1 - 0.0058 16.1 4.8 0.27 10.6 0.0 3.5 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus CT_C_D PF02682.16 CBY13796.1 - 0.037 13.8 0.1 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D DRY_EERY PF09750.9 CBY13796.1 - 0.037 14.3 0.8 0.13 12.5 0.7 1.9 2 0 0 2 2 2 0 Alternative splicing regulator Sec23_helical PF04815.15 CBY13796.1 - 0.044 13.6 0.5 5.9 6.8 0.0 3.9 3 1 1 4 4 4 0 Sec23/Sec24 helical domain Dict-STAT-coil PF09267.10 CBY13796.1 - 0.11 12.9 2.5 0.12 12.8 0.5 2.1 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil DUF4795 PF16043.5 CBY13796.1 - 0.4 10.3 5.6 3.3 7.3 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) PTPlike_phytase PF14566.6 CBY13796.1 - 0.77 9.9 2.8 1.2 9.3 0.5 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate Dor1 PF04124.12 CBY13796.1 - 1.1 7.8 6.5 0.33 9.6 1.0 2.9 3 0 0 3 3 3 0 Dor1-like family COG5 PF10392.9 CBY13796.1 - 1.3 9.2 9.9 0.18 12.0 0.4 3.5 4 0 0 4 4 4 0 Golgi transport complex subunit 5 DnaJ PF00226.31 CBY13797.1 - 9e-29 99.4 1.4 2e-28 98.3 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 CBY13797.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein Sld5 PF05916.11 CBY13798.1 - 5.6e-16 59.0 0.7 1.1e-15 58.0 0.7 1.5 1 0 0 1 1 1 1 GINS complex protein WD40 PF00400.32 CBY13800.1 - 2.6e-60 199.0 11.8 2.4e-08 34.5 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY13800.1 - 4.4e-16 59.0 0.5 0.0027 18.0 0.0 6.2 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY13800.1 - 2.8e-08 33.9 0.0 5.3e-05 23.2 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBY13800.1 - 6.1e-05 22.1 0.8 1.1 8.1 0.0 4.5 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CBY13800.1 - 0.02 13.4 0.0 1.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain POLO_box PF00659.18 CBY13800.1 - 0.067 13.4 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 POLO box duplicated region DASH_Spc19 PF08287.11 CBY13800.1 - 0.12 12.2 1.9 0.19 11.6 1.9 1.3 1 0 0 1 1 1 0 Spc19 DnaJ PF00226.31 CBY13801.1 - 8.4e-13 48.2 2.3 1.8e-12 47.2 0.1 2.9 3 0 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 CBY13801.1 - 2.6e-09 37.1 0.5 2.6e-09 37.1 0.5 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain RAC_head PF16717.5 CBY13801.1 - 4.6e-09 37.1 7.8 4.6e-09 37.1 7.8 3.9 3 1 0 4 4 4 1 Ribosome-associated complex head domain Myb_DNA-bind_6 PF13921.6 CBY13801.1 - 5.3e-05 23.4 3.1 0.00016 21.8 0.3 3.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Sulfotransfer_2 PF03567.14 CBY13801.1 - 0.3 11.0 6.4 0.035 14.0 1.4 2.0 2 1 0 2 2 2 0 Sulfotransferase family LCAT PF02450.15 CBY13802.1 - 1.8e-50 172.3 4.7 3.5e-47 161.4 0.8 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 CBY13802.1 - 0.0017 17.9 0.0 0.0042 16.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 CBY13802.1 - 0.0033 17.0 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_6 PF12697.7 CBY13802.1 - 0.031 14.9 0.0 0.048 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 CBY13802.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF3963 PF13124.6 CBY13802.1 - 0.16 12.0 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) UBN_AB PF14075.6 CBY13803.1 - 1e-50 172.5 6.8 1e-50 172.5 6.8 3.0 3 0 0 3 3 3 2 Ubinuclein conserved middle domain HUN PF08729.10 CBY13803.1 - 6.8e-19 67.6 2.1 1.5e-18 66.5 2.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain rve PF00665.26 CBY13804.1 - 8e-11 42.2 0.0 2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CBY13804.1 - 0.0037 17.0 0.1 0.0086 15.8 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain GMC_oxred_C PF05199.13 CBY13805.1 - 7.7e-16 58.9 0.2 9.6e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pkinase PF00069.25 CBY13806.1 - 6.5e-08 32.3 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13806.1 - 2.3e-05 23.8 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.6 CBY13806.1 - 0.15 12.3 1.9 5.6 7.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) TFIIA PF03153.13 CBY13807.1 - 0.14 12.1 6.1 0.18 11.8 6.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH PF17917.1 CBY13808.1 - 3.2e-27 94.9 0.4 9.4e-27 93.4 0.4 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY13808.1 - 1.1e-24 86.4 0.0 2.9e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY13808.1 - 3.4e-19 69.2 0.2 2.2e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CBY13808.1 - 7.6e-16 58.3 0.2 1.7e-15 57.1 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY13808.1 - 3.8e-13 49.3 0.5 1.2e-12 47.7 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 CBY13808.1 - 0.033 14.0 0.1 0.079 12.7 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain Sulfotransfer_1 PF00685.27 CBY13809.1 - 0.0037 16.8 0.1 0.0041 16.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY13810.1 - 0.0015 19.0 0.0 0.0027 18.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY13810.1 - 0.031 13.8 0.1 0.056 12.9 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase domain Carboxyl_trans PF01039.22 CBY13811.1 - 4.5e-68 230.1 0.0 1.6e-67 228.3 0.0 1.7 2 0 0 2 2 2 1 Carboxyl transferase domain ECH_1 PF00378.20 CBY13811.1 - 0.07 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Zona_pellucida PF00100.23 CBY13812.1 - 4.3e-32 111.9 4.6 5.4e-32 111.6 4.6 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Ninjurin PF04923.12 CBY13813.1 - 4.9e-08 32.8 4.5 2.9e-07 30.4 4.5 2.0 1 1 0 1 1 1 1 Ninjurin Annexin PF00191.20 CBY13814.1 - 4.7e-64 212.4 15.6 4.8e-25 87.4 0.3 4.5 5 0 0 5 5 5 4 Annexin RicinB_lectin_2 PF14200.6 CBY13814.1 - 1.1e-11 45.3 0.1 0.00019 22.1 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CBY13814.1 - 8.6e-08 32.5 0.0 1.8e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Ribosomal_S4Pg PF11993.8 CBY13814.1 - 0.046 13.8 0.2 0.38 10.8 0.1 2.3 3 0 0 3 3 3 0 Ribosomal S4P (gammaproteobacterial) RB_A PF01858.17 CBY13814.1 - 0.095 12.5 0.1 4.5 7.1 0.0 2.9 2 1 1 3 3 3 0 Retinoblastoma-associated protein A domain DUF4611 PF15387.6 CBY13814.1 - 1 9.6 10.8 0.078 13.2 3.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Phage_TAC_4 PF08748.11 CBY13814.1 - 2.2 8.6 5.6 2.7 8.3 0.7 3.1 3 0 0 3 3 3 0 Phage tail assembly chaperone BSP_II PF05432.11 CBY13814.1 - 5.4 6.6 13.4 0.068 12.9 5.4 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Trypsin PF00089.26 CBY13815.1 - 1.2e-57 195.2 1.1 2.2e-57 194.4 0.1 1.8 2 0 0 2 2 2 1 Trypsin SRCR PF00530.18 CBY13815.1 - 8.7e-21 74.3 1.9 8.7e-21 74.3 1.9 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 CBY13815.1 - 8.6e-06 26.7 0.0 2.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Sushi PF00084.20 CBY13815.1 - 0.00014 22.4 9.5 0.00044 20.8 7.5 2.9 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) SRCR_2 PF15494.6 CBY13815.1 - 0.00015 22.3 0.1 0.0004 20.9 0.1 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 CBY13815.1 - 0.00049 20.5 0.1 0.001 19.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CBM_14 PF01607.24 CBY13815.1 - 0.22 11.7 10.9 2.1 8.6 1.0 3.2 2 1 0 2 2 2 0 Chitin binding Peritrophin-A domain EGF_2 PF07974.13 CBY13815.1 - 0.72 10.3 14.3 0.041 14.2 7.2 2.8 2 0 0 2 2 2 0 EGF-like domain SHIPPO-rpt PF07004.12 CBY13817.1 - 6.4e-18 64.7 23.3 2.7e-05 24.9 0.6 5.4 5 0 0 5 5 5 5 Sperm-tail PG-rich repeat Band_7 PF01145.25 CBY13818.1 - 7.2e-30 104.3 0.6 9.2e-30 104.0 0.6 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY13818.1 - 0.0018 18.0 0.1 0.0024 17.6 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 CBY13818.1 - 0.096 13.1 0.7 0.28 11.6 0.4 1.9 1 1 0 1 1 1 0 Phage protein Gp68 Sec5 PF15469.6 CBY13819.1 - 0.069 13.0 0.1 0.094 12.5 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 AA_permease_2 PF13520.6 CBY13821.1 - 6.2e-31 107.7 14.7 8.4e-31 107.2 14.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY13821.1 - 5.1e-16 58.3 13.5 7.7e-16 57.7 13.5 1.2 1 0 0 1 1 1 1 Amino acid permease Trypsin PF00089.26 CBY13822.1 - 3.7e-51 174.1 1.1 4.5e-51 173.8 1.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY13822.1 - 8.3e-05 23.5 0.2 0.00014 22.8 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY13822.1 - 0.0043 17.4 0.2 0.008 16.6 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Endonuc-EcoRV PF09233.11 CBY13822.1 - 0.15 11.4 0.0 0.79 9.0 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease EcoRV Histone PF00125.24 CBY13823.1 - 5.5e-51 172.3 2.0 6.2e-51 172.2 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY13823.1 - 0.00021 21.4 0.4 0.00033 20.8 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY13823.1 - 0.00025 21.6 1.5 0.00028 21.5 1.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY13823.1 - 0.0012 19.2 0.0 0.0018 18.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY13823.1 - 0.084 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TMA7 PF09072.10 CBY13823.1 - 0.1 13.4 3.0 0.21 12.4 3.0 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 Sirohm_synth_M PF14824.6 CBY13823.1 - 1.3 8.5 3.8 4.7 6.8 0.4 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Pkinase PF00069.25 CBY13824.1 - 1.9e-69 234.0 0.3 2.9e-69 233.4 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13824.1 - 9.9e-39 133.2 0.2 1.8e-38 132.3 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CBY13824.1 - 3.5e-29 100.8 0.4 1.6e-16 60.3 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 CBY13824.1 - 1.2e-05 24.3 0.0 2.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Knl1_RWD_C PF18210.1 CBY13824.1 - 0.15 12.6 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 Knl1 RWD C-terminal domain Gcd10p PF04189.13 CBY13825.1 - 5e-44 150.6 0.2 6.7e-44 150.2 0.2 1.3 1 0 0 1 1 1 1 Gcd10p family baeRF_family8 PF18851.1 CBY13825.1 - 0.016 15.3 0.2 0.042 13.9 0.2 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 DENN PF02141.21 CBY13826.1 - 2.1e-33 115.8 1.9 3.4e-33 115.2 0.9 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 CBY13826.1 - 3.1e-06 27.8 0.1 9.6e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 CBY13826.1 - 0.00057 19.8 0.3 0.0019 18.1 0.1 2.0 2 0 0 2 2 2 1 dDENN domain SPA PF08616.10 CBY13826.1 - 0.028 14.4 0.0 0.079 12.9 0.0 1.8 1 0 0 1 1 1 0 Stabilization of polarity axis DUF2465 PF10239.9 CBY13827.1 - 2.5e-67 227.4 1.9 3.8e-67 226.8 1.9 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2465) PRIMA1 PF16101.5 CBY13828.1 - 0.039 14.0 0.4 0.075 13.1 0.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Csm1_N PF18504.1 CBY13828.1 - 0.051 13.9 11.3 3.1 8.2 1.6 3.6 3 0 0 3 3 3 0 Csm1 N-terminal domain Helicase_IV_N PF12462.8 CBY13828.1 - 0.17 11.8 8.7 0.072 13.0 4.6 2.3 2 1 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal FlaC_arch PF05377.11 CBY13828.1 - 0.61 10.5 6.3 22 5.6 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ZapD PF07072.11 CBY13828.1 - 1.4 8.6 9.3 0.24 11.2 3.8 2.1 2 0 0 2 2 2 0 Cell division protein Occludin_ELL PF07303.13 CBY13828.1 - 1.6 9.5 14.0 2.1 9.1 3.6 3.2 2 1 1 3 3 3 0 Occludin homology domain DivIC PF04977.15 CBY13828.1 - 1.6 8.6 14.2 3.2 7.6 0.8 3.6 3 1 1 4 4 4 0 Septum formation initiator DUF4200 PF13863.6 CBY13828.1 - 2.4 8.6 19.7 13 6.2 1.3 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) LMBR1 PF04791.16 CBY13828.1 - 5 5.9 6.7 1 8.2 2.6 1.6 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF1003 PF06210.11 CBY13828.1 - 5.5 7.1 6.1 1.7 8.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) DASH_Dam1 PF08653.10 CBY13828.1 - 5.7 6.8 6.1 98 2.9 1.0 4.0 3 1 0 3 3 3 0 DASH complex subunit Dam1 Med9 PF07544.13 CBY13828.1 - 7.2 6.8 12.3 5.8 7.1 0.3 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 NUDIX_2 PF13869.6 CBY13829.1 - 5.9e-64 215.1 0.0 6.7e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase eIF-3_zeta PF05091.12 CBY13830.1 - 2.2e-179 597.8 4.3 2.6e-179 597.6 4.3 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 CBY13830.1 - 1.6e-05 24.5 0.9 3.3e-05 23.5 0.9 1.4 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus SLC35F PF06027.12 CBY13831.1 - 1.4e-42 146.3 18.6 1.6e-42 146.1 18.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 CBY13831.1 - 1.2e-05 24.7 12.3 1.5e-05 24.4 12.3 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBY13831.1 - 3e-05 24.2 24.5 0.0014 18.8 13.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CBY13831.1 - 3.2e-05 23.0 2.8 3.2e-05 23.0 2.8 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 CBY13831.1 - 0.00064 19.0 4.0 0.00085 18.6 4.0 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF2105 PF09878.9 CBY13831.1 - 0.019 14.7 2.9 0.019 14.7 2.9 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2105) DUF523 PF04463.12 CBY13832.1 - 0.026 14.6 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF523) TatD_DNase PF01026.21 CBY13834.1 - 8.4e-48 163.0 0.0 1.2e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Nsp1_C PF05064.13 CBY13835.1 - 3.5e-26 91.3 6.7 5.9e-26 90.6 6.7 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 CBY13835.1 - 4.4e-06 27.4 21.1 4.4e-06 27.4 21.1 3.8 1 1 2 3 3 3 2 Nucleoporin FG repeat region Laminin_I PF06008.14 CBY13835.1 - 0.002 17.9 5.2 0.002 17.9 5.2 1.6 1 1 0 1 1 1 1 Laminin Domain I Nucleoporin_FG2 PF15967.5 CBY13835.1 - 0.0026 16.4 83.3 0.055 12.0 34.2 2.1 1 1 1 2 2 2 2 Nucleoporin FG repeated region DUF812 PF05667.11 CBY13835.1 - 0.0096 14.9 2.9 0.012 14.5 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF1465 PF07323.12 CBY13835.1 - 0.086 12.7 1.8 0.15 11.9 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF2048 PF09752.9 CBY13835.1 - 0.14 11.2 6.2 0.059 12.5 3.4 1.7 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Fib_alpha PF08702.10 CBY13835.1 - 0.15 12.3 3.2 0.34 11.1 0.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4164 PF13747.6 CBY13835.1 - 0.18 12.1 4.6 0.11 12.8 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Ead_Ea22 PF13935.6 CBY13835.1 - 0.38 11.4 4.1 0.71 10.5 3.9 1.5 1 1 0 1 1 1 0 Ead/Ea22-like protein Snapin_Pallidin PF14712.6 CBY13835.1 - 0.47 10.9 4.3 0.61 10.5 2.9 1.9 1 1 1 2 2 2 0 Snapin/Pallidin APG6_N PF17675.1 CBY13835.1 - 0.69 10.5 6.4 0.83 10.2 5.3 1.6 1 1 1 2 2 2 0 Apg6 coiled-coil region SYCE1 PF15233.6 CBY13835.1 - 1.1 9.3 7.0 0.26 11.4 4.0 1.5 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Seryl_tRNA_N PF02403.22 CBY13835.1 - 2.5 8.3 8.2 2.4 8.4 2.0 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.16 CBY13835.1 - 3.3 8.2 7.3 20 5.7 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 CBY13835.1 - 6.8 6.7 5.9 27 4.8 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rieske PF00355.26 CBY13836.1 - 2.8e-11 43.2 0.1 5e-11 42.4 0.1 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CBY13836.1 - 0.00022 21.6 0.1 0.00038 20.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region LETM1 PF07766.13 CBY13837.1 - 1.3e-16 60.7 0.0 8.5e-09 35.1 0.0 2.3 1 1 1 2 2 2 2 LETM1-like protein CEP76-C2 PF15627.6 CBY13838.1 - 1e-38 132.4 0.2 1.8e-38 131.6 0.2 1.4 1 0 0 1 1 1 1 CEP76 C2 domain G-patch PF01585.23 CBY13838.1 - 2.7e-12 46.4 3.2 4.5e-12 45.7 1.6 2.1 2 0 0 2 2 2 1 G-patch domain C2 PF00168.30 CBY13838.1 - 0.083 13.2 0.1 0.27 11.6 0.1 1.9 1 1 0 1 1 1 0 C2 domain G-patch_2 PF12656.7 CBY13838.1 - 3 8.0 5.2 0.34 11.0 0.5 1.8 2 0 0 2 2 2 0 G-patch domain Mid2 PF04478.12 CBY13839.1 - 0.026 14.4 0.3 0.04 13.7 0.3 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor zf-C2H2 PF00096.26 CBY13840.1 - 5.5e-13 48.6 31.6 0.014 15.8 0.1 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY13840.1 - 5.1e-10 39.4 18.3 0.032 14.5 0.8 5.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY13840.1 - 8.6e-09 35.4 29.7 1.6e-06 28.3 0.7 6.1 6 0 0 6 6 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY13840.1 - 4.3e-08 33.3 34.8 0.011 16.5 0.3 6.9 7 0 0 7 7 6 4 C2H2-type zinc finger zf-Di19 PF05605.12 CBY13840.1 - 1e-07 32.1 18.6 0.00021 21.5 1.3 4.5 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY13840.1 - 6.4e-07 29.5 20.3 0.0021 18.4 0.7 6.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type FYVE PF01363.21 CBY13840.1 - 6.2e-05 23.1 1.7 5.2 7.3 1.5 4.5 3 1 0 3 3 3 2 FYVE zinc finger zf-C2H2_3rep PF18868.1 CBY13840.1 - 0.00027 21.6 19.0 3.4 8.4 3.1 6.0 2 1 3 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 CBY13840.1 - 0.00094 18.9 2.6 0.012 15.3 1.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc-finger domain GAGA PF09237.11 CBY13840.1 - 0.016 15.0 10.1 1.8 8.5 0.1 3.9 4 1 0 4 4 3 0 GAGA factor zf-C2H2_2 PF12756.7 CBY13840.1 - 0.027 14.8 30.4 0.036 14.4 1.8 5.4 2 1 5 7 7 6 0 C2H2 type zinc-finger (2 copies) TPMT PF05724.11 CBY13840.1 - 0.038 13.7 0.1 0.096 12.3 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Zn-ribbon_8 PF09723.10 CBY13840.1 - 0.043 13.9 2.1 0.043 13.9 2.1 4.2 3 1 0 3 3 3 0 Zinc ribbon domain WAC_Acf1_DNA_bd PF10537.9 CBY13840.1 - 0.15 12.6 1.5 11 6.6 0.0 3.0 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal zf-C2H2_9 PF16293.5 CBY13840.1 - 0.42 10.5 12.5 8.8 6.3 0.1 5.6 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 CBY13840.1 - 0.75 9.5 21.0 0.64 9.7 0.1 5.0 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3268 PF11672.8 CBY13840.1 - 1.4 9.3 7.4 2.4 8.5 0.1 2.9 3 0 0 3 3 3 0 zinc-finger-containing domain zf-C2HE PF16278.5 CBY13840.1 - 1.5 9.3 21.0 1.2 9.6 1.4 4.4 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger c-SKI_SMAD_bind PF08782.10 CBY13840.1 - 1.8 8.9 0.0 1.8 8.9 0.0 3.8 4 1 1 5 5 5 0 c-SKI Smad4 binding domain zf-C2H2_6 PF13912.6 CBY13840.1 - 6.7 6.8 33.2 0.75 9.9 0.3 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger Pkinase PF00069.25 CBY13842.1 - 7.8e-60 202.5 1.1 1.8e-58 198.0 0.0 3.0 4 0 0 4 4 4 1 Protein kinase domain cNMP_binding PF00027.29 CBY13842.1 - 3e-37 126.6 0.2 6.4e-19 67.8 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY13842.1 - 3e-27 95.5 0.0 2.1e-26 92.8 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY13842.1 - 8.7e-05 22.0 0.3 0.00019 20.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CBY13842.1 - 0.01 14.9 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CBY13842.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CHDCT2 PF08074.11 CBY13842.1 - 0.14 12.3 7.3 0.41 10.8 7.3 1.8 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain V_ATPase_I PF01496.19 CBY13842.1 - 0.25 9.2 10.7 0.39 8.6 10.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 CBY13842.1 - 0.64 10.1 2.9 1.8 8.6 2.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4407 PF14362.6 CBY13842.1 - 2.2 7.6 13.9 4.3 6.6 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 CBY13842.1 - 4.4 7.4 22.4 3.8 7.5 15.9 2.7 1 1 1 2 2 2 0 FlxA-like protein Ets PF00178.22 CBY13844.1 - 2.1e-35 121.1 1.0 2.1e-35 121.1 1.0 1.7 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 CBY13844.1 - 5.2e-13 48.8 0.3 1.1e-12 47.7 0.3 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Lyase_aromatic PF00221.19 CBY13845.1 - 1.7e-168 561.1 0.2 1.9e-168 560.9 0.2 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase EF-hand_1 PF00036.32 CBY13846.1 - 3.4e-05 23.1 8.1 0.85 9.3 0.0 4.6 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBY13846.1 - 5.9e-05 22.7 6.6 0.59 10.2 0.3 4.6 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY13846.1 - 0.0019 18.6 12.8 0.063 13.7 1.3 3.5 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY13846.1 - 0.17 11.4 7.8 4.6 6.9 0.0 3.8 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 CBY13846.1 - 0.32 10.9 8.4 0.68 9.8 0.1 3.6 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_1 PF00036.32 CBY13848.1 - 7.4e-28 94.0 14.5 9.3e-08 31.1 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY13848.1 - 2e-26 92.2 6.2 3.2e-13 49.9 3.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY13848.1 - 2.1e-22 77.1 10.5 3.4e-07 29.7 0.0 4.6 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CBY13848.1 - 1e-20 73.3 13.1 3.7e-11 42.7 1.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CBY13848.1 - 7.1e-16 58.3 0.2 2.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY13848.1 - 5.3e-06 25.7 17.2 0.00055 19.3 0.7 5.0 5 1 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 CBY13848.1 - 1.2e-05 25.1 5.3 0.006 16.5 1.2 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBY13848.1 - 0.00016 22.5 0.3 0.1 13.5 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 CBY13848.1 - 0.001 19.3 0.7 0.88 10.0 0.0 2.7 1 1 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CBY13848.1 - 0.0019 18.4 0.2 0.0067 16.6 0.1 1.9 1 1 1 2 2 2 1 Dockerin type I domain SUB1_ProdP9 PF18213.1 CBY13848.1 - 0.0027 17.5 1.3 0.01 15.7 0.3 2.1 2 0 0 2 2 2 1 SUB1 protease Prodomain ProdP9 SurA_N_2 PF13623.6 CBY13848.1 - 0.026 14.4 3.0 3.5 7.5 0.1 2.7 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 CBY13848.1 - 0.035 12.7 0.1 0.26 9.8 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Caleosin PF05042.13 CBY13848.1 - 0.038 13.9 0.2 8.4 6.3 0.0 3.0 1 1 2 3 3 3 0 Caleosin related protein FlgD PF03963.14 CBY13848.1 - 0.041 14.2 0.1 0.073 13.4 0.1 1.6 1 1 0 1 1 1 0 Flagellar hook capping protein - N-terminal region TerB PF05099.13 CBY13848.1 - 0.072 13.0 3.8 5.9 6.8 0.6 3.0 1 1 2 3 3 3 0 Tellurite resistance protein TerB MgtE_N PF03448.17 CBY13848.1 - 0.13 12.9 2.8 0.13 12.9 0.8 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain SPARC_Ca_bdg PF10591.9 CBY13848.1 - 0.24 11.7 4.0 0.45 10.8 1.9 2.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Malate_DH PF12434.8 CBY13848.1 - 0.51 10.4 3.7 0.22 11.6 0.8 1.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme TTL PF03133.15 CBY13849.1 - 5.9e-68 229.1 0.9 1.9e-67 227.4 0.2 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY13849.1 - 1.1e-06 28.1 0.2 2.2e-05 23.9 0.1 2.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY13849.1 - 0.06 12.6 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Ntox46 PF15538.6 CBY13849.1 - 0.068 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 46 OstA PF03968.14 CBY13849.1 - 0.1 12.8 0.9 0.35 11.1 0.9 2.0 1 1 0 1 1 1 0 OstA-like protein Fibrinogen_C PF00147.18 CBY13850.1 - 2.5e-40 138.6 17.6 8.4e-29 101.0 9.9 4.0 2 2 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.10 CBY13850.1 - 2e-06 28.1 0.2 4.9e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family PEP-utilisers_N PF05524.13 CBY13850.1 - 0.15 12.2 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TSP_1 PF00090.19 CBY13851.1 - 2.1e-11 43.8 10.6 2.1e-11 43.8 10.6 2.8 3 1 1 4 4 4 1 Thrombospondin type 1 domain CarboxypepD_reg PF13620.6 CBY13851.1 - 0.02 15.1 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain VWA PF00092.28 CBY13852.1 - 4.3e-08 33.6 0.0 6.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain AbrB_C PF18277.1 CBY13852.1 - 0.024 14.2 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 AbrB C-terminal domain Exo_endo_phos_2 PF14529.6 CBY13852.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Pkinase PF00069.25 CBY13853.1 - 6.7e-10 38.8 0.7 1.3e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13853.1 - 9.4e-09 34.9 0.1 2e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3823_C PF18003.1 CBY13853.1 - 0.22 12.3 1.0 6.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3823_C) VWA PF00092.28 CBY13854.1 - 1.6e-107 357.4 17.0 1.4e-34 119.8 0.0 5.2 4 1 1 5 5 5 5 von Willebrand factor type A domain VWA_2 PF13519.6 CBY13854.1 - 1.3e-43 148.0 8.0 2.6e-16 60.2 0.0 4.3 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_3 PF13768.6 CBY13854.1 - 7.4e-14 52.0 0.8 0.00018 21.5 0.0 5.2 4 1 1 5 5 5 3 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY13854.1 - 1e-05 25.1 4.9 0.0031 16.9 0.0 3.9 4 1 1 5 5 5 2 VWA domain containing CoxE-like protein DUF1194 PF06707.11 CBY13854.1 - 9.6e-05 21.7 3.8 0.017 14.3 0.0 4.0 4 1 0 4 4 4 2 Protein of unknown function (DUF1194) DUF2201 PF09967.9 CBY13854.1 - 0.0029 17.8 3.1 5.1 7.3 0.0 3.6 3 0 0 3 3 3 2 VWA-like domain (DUF2201) AbrB_C PF18277.1 CBY13854.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 AbrB C-terminal domain Pkinase PF00069.25 CBY13855.1 - 3e-21 76.0 0.1 1.2e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13855.1 - 2.9e-17 62.8 0.0 1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SAA PF00277.18 CBY13856.1 - 0.021 15.3 0.1 0.48 10.9 0.0 2.0 1 1 1 2 2 2 0 Serum amyloid A protein PI3K_P85_iSH2 PF16454.5 CBY13856.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TFIIA PF03153.13 CBY13857.1 - 2.1 8.2 49.2 2.6 7.9 49.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CBY13857.1 - 3.9 6.9 15.5 4.9 6.6 15.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LAP1C PF05609.12 CBY13857.1 - 5.3 6.0 26.9 6.4 5.8 26.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ECM1 PF05782.11 CBY13857.1 - 9.7 5.0 27.5 12 4.7 27.5 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Amidase PF01425.21 CBY13858.1 - 2e-15 56.8 0.0 1.1e-14 54.3 0.0 1.8 1 1 0 1 1 1 1 Amidase Orbi_VP1 PF05788.12 CBY13859.1 - 0.006 14.3 0.2 0.006 14.3 0.2 1.0 1 0 0 1 1 1 1 Orbivirus RNA-dependent RNA polymerase (VP1) Phosphodiest PF01663.22 CBY13860.1 - 1.1e-57 196.3 0.1 1.4e-57 195.9 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 CBY13860.1 - 5.5e-06 26.7 10.4 1.7e-05 25.1 10.4 1.9 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.23 CBY13860.1 - 0.032 13.6 0.0 0.24 10.7 0.0 2.4 1 1 0 1 1 1 0 Sulfatase PglZ PF08665.12 CBY13860.1 - 0.21 11.6 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 PglZ domain RVT_1 PF00078.27 CBY13861.1 - 6.3e-27 94.5 0.0 1.5e-26 93.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3216 PF11505.8 CBY13861.1 - 0.11 12.7 0.1 0.33 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Phosphodiest PF01663.22 CBY13863.1 - 9.9e-58 196.4 0.1 1.4e-57 195.9 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 CBY13863.1 - 7.7e-06 26.2 10.4 1.8e-05 25.1 10.4 1.6 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.23 CBY13863.1 - 0.034 13.5 0.0 0.25 10.7 0.0 2.3 1 1 0 1 1 1 0 Sulfatase PglZ PF08665.12 CBY13863.1 - 0.18 11.9 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 PglZ domain TauD PF02668.16 CBY13864.1 - 1.2e-27 97.4 0.0 2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CBY13864.1 - 1e-05 26.1 0.0 2.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 CBY13864.1 - 0.0015 17.7 0.0 0.0037 16.4 0.0 1.6 1 1 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.6 CBY13864.1 - 0.11 13.4 0.0 40 5.2 0.0 3.2 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Trypsin PF00089.26 CBY13865.1 - 3e-32 112.2 0.5 4.5e-32 111.6 0.5 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY13865.1 - 0.029 15.3 0.0 0.053 14.4 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S6 PF02395.16 CBY13865.1 - 0.093 10.7 0.1 0.11 10.5 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease G_path_suppress PF15991.5 CBY13865.1 - 0.81 9.8 3.1 1.1 9.4 3.1 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor EF-hand_1 PF00036.32 CBY13866.1 - 2.8e-08 32.7 1.0 0.00013 21.3 0.1 3.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY13866.1 - 1.5e-06 28.5 0.9 0.0086 16.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY13866.1 - 3e-05 23.6 7.2 0.0011 18.8 0.3 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBY13866.1 - 0.0002 21.1 0.2 0.0057 16.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY13866.1 - 0.00022 20.5 0.1 0.00022 20.5 0.1 3.3 3 0 0 3 3 3 2 EF hand Trypsin PF00089.26 CBY13868.1 - 2.8e-109 364.1 9.1 6.4e-45 153.6 0.2 3.5 3 0 0 3 3 3 3 Trypsin DUF1986 PF09342.11 CBY13868.1 - 5.8e-18 65.4 0.3 4.8e-12 46.3 0.2 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF1986) EGF_CA PF07645.15 CBY13868.1 - 4.9e-09 36.3 32.9 1.2e-08 35.0 12.5 8.4 10 0 0 10 10 10 4 Calcium-binding EGF domain EGF PF00008.27 CBY13868.1 - 1.8e-08 34.5 25.0 1.1e-07 32.0 11.0 10.3 11 0 0 11 11 11 5 EGF-like domain hEGF PF12661.7 CBY13868.1 - 3.2e-05 24.4 17.2 5.3e-05 23.7 9.1 10.8 11 0 0 11 11 11 3 Human growth factor-like EGF cEGF PF12662.7 CBY13868.1 - 0.00022 21.1 3.6 0.00022 21.1 3.6 6.7 6 0 0 6 6 6 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY13868.1 - 0.00073 19.7 6.2 0.00073 19.7 6.2 9.6 9 0 0 9 9 9 3 EGF domain Glyco_transf_7C PF02709.14 CBY13869.1 - 7.4e-28 96.0 0.3 7.4e-28 96.0 0.3 1.6 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CBY13869.1 - 3e-21 75.4 0.8 4.6e-21 74.9 0.8 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 DUF87 PF01935.17 CBY13870.1 - 0.075 13.1 7.0 0.096 12.8 6.4 1.4 1 1 0 1 1 1 0 Helicase HerA, central domain V_ATPase_I PF01496.19 CBY13870.1 - 0.1 10.5 2.8 0.1 10.5 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 CBY13870.1 - 0.12 10.3 1.9 0.16 9.9 1.9 1.1 1 0 0 1 1 1 0 Prominin ACR_tran PF00873.19 CBY13870.1 - 0.24 9.0 1.2 0.29 8.7 1.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MapZ_EC1 PF18041.1 CBY13870.1 - 0.88 9.8 7.5 5.1 7.3 7.5 2.1 1 1 0 1 1 1 0 MapZ extracellular domain 1 ABC_tran_Xtn PF12848.7 CBY13870.1 - 4.2 7.5 11.5 4.8 7.3 5.3 2.9 1 1 2 3 3 3 0 ABC transporter MCU PF04678.13 CBY13870.1 - 4.9 7.2 8.4 2.4 8.2 5.4 2.1 2 1 0 2 2 2 0 Mitochondrial calcium uniporter DEAD PF00270.29 CBY13871.1 - 1.2e-46 158.6 0.0 2.9e-46 157.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY13871.1 - 9.5e-27 93.5 0.0 3.4e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LSM PF01423.22 CBY13872.1 - 2.4e-21 75.2 0.2 2.9e-21 74.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF3585 PF12130.8 CBY13873.1 - 2.6e-20 72.9 21.2 2.6e-20 72.9 21.2 2.4 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 CBY13873.1 - 3e-09 37.0 0.1 8.2e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Pyr_redox_2 PF07992.14 CBY13873.1 - 0.0001 21.6 0.9 0.00018 20.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY13873.1 - 0.00017 20.9 0.6 0.00073 18.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 CBY13873.1 - 0.0013 19.1 0.0 0.0055 17.1 0.0 2.1 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 CBY13873.1 - 0.0019 17.5 0.0 0.0056 16.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY13873.1 - 0.0028 16.8 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CBY13873.1 - 0.0036 16.1 0.0 0.0036 16.1 0.0 2.8 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox PF00070.27 CBY13873.1 - 0.0072 16.9 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CBY13873.1 - 0.011 15.1 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CBY13873.1 - 0.96 9.3 8.0 3.2 7.6 0.0 3.5 3 1 1 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C4 PF00105.18 CBY13874.1 - 9.7e-14 51.6 13.9 1.3e-13 51.2 13.9 1.1 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) BaffR-Tall_bind PF09256.10 CBY13874.1 - 0.075 12.8 3.2 0.18 11.6 3.2 1.8 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding C1_1 PF00130.22 CBY13874.1 - 4 7.4 13.6 0.098 12.6 1.8 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TfoX_C PF04994.13 CBY13875.1 - 0.13 12.4 0.1 3 8.0 0.0 2.3 2 0 0 2 2 2 0 TfoX C-terminal domain Glyco_transf_24 PF18404.1 CBY13876.1 - 1.7e-127 424.4 5.2 5.7e-127 422.7 3.4 2.4 2 1 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CBY13876.1 - 2.4e-40 139.1 1.1 6.6e-36 124.6 0.1 3.5 2 1 1 3 3 3 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CBY13876.1 - 3e-33 114.2 0.0 6.6e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 CBY13876.1 - 1.3e-22 80.2 0.0 1.1e-21 77.1 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 CBY13876.1 - 3.8e-11 43.2 0.0 9.3e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 CBY13876.1 - 2.9e-06 27.4 0.9 0.0066 16.4 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CBY13876.1 - 4.8e-06 26.3 1.3 1.7e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 8 GST_N PF02798.20 CBY13877.1 - 5.9e-29 100.2 0.1 1.9e-13 50.6 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY13877.1 - 1.7e-27 95.6 0.1 3.2e-13 49.9 0.0 2.7 3 0 0 3 3 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY13877.1 - 1e-20 73.8 0.0 1.7e-09 37.8 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CBY13877.1 - 7.1e-14 51.4 0.1 3.8e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY13877.1 - 3.2e-13 49.5 0.0 2.7e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY13877.1 - 1.3e-12 47.7 4.0 3.2e-08 33.7 0.0 2.9 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY13877.1 - 6.2e-12 45.6 3.9 1.7e-07 31.3 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CBY13877.1 - 2.7e-05 24.8 0.0 0.2 12.4 0.0 2.8 3 0 0 3 3 3 2 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 CBY13877.1 - 0.012 15.9 0.0 0.59 10.4 0.1 2.7 2 0 0 2 2 2 0 Glutaredoxin BUD22 PF09073.10 CBY13877.1 - 0.013 14.9 0.5 0.017 14.5 0.5 1.2 1 0 0 1 1 1 0 BUD22 GluRS_N PF18466.1 CBY13877.1 - 0.048 14.1 0.0 18 5.9 0.0 2.9 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain Glyco_hydro_35 PF01301.19 CBY13879.1 - 2.3e-103 346.1 1.1 3.4e-103 345.6 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY13879.1 - 1.3e-12 47.8 3.1 8.7e-12 45.1 3.1 2.2 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 CBY13879.1 - 0.00027 21.5 0.1 0.0025 18.3 0.0 2.4 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain GAD-like PF08887.11 CBY13879.1 - 0.0054 16.5 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 GAD-like domain Granin PF01271.17 CBY13879.1 - 0.18 10.7 0.1 0.24 10.3 0.1 1.1 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) B56 PF01603.20 CBY13881.1 - 3.4e-40 138.3 0.0 3.9e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.20 CBY13882.1 - 5.8e-47 160.6 10.2 6.5e-47 160.4 10.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CBY13882.1 - 0.059 13.3 1.8 2.3 8.1 1.8 2.3 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2475 PF10629.9 CBY13883.1 - 0.0021 18.2 5.5 0.028 14.6 0.3 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2475) DnaJ PF00226.31 CBY13884.1 - 5.1e-20 71.4 0.8 7.9e-20 70.8 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain Prominin PF05478.11 CBY13884.1 - 0.027 12.4 9.3 0.032 12.2 9.3 1.1 1 0 0 1 1 1 0 Prominin Renin_r PF07850.14 CBY13885.1 - 0.022 15.3 0.0 0.056 14.1 0.0 1.6 1 1 0 1 1 1 0 Renin receptor-like protein DnaJ PF00226.31 CBY13886.1 - 1.5e-24 85.9 2.8 2.2e-24 85.3 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain Prominin PF05478.11 CBY13886.1 - 0.033 12.2 8.7 0.041 11.9 8.7 1.1 1 0 0 1 1 1 0 Prominin FXa_inhibition PF14670.6 CBY13887.1 - 5.8e-11 42.5 22.1 1.2e-05 25.5 8.7 2.5 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 CBY13887.1 - 0.064 13.8 3.8 7.8 7.1 0.0 5.0 6 1 0 6 6 6 0 Low-density lipoprotein receptor repeat class B PA28_alpha PF02251.18 CBY13888.1 - 4.5e-07 29.8 0.3 9.8e-07 28.7 0.2 1.6 1 1 0 1 1 1 1 Proteasome activator pa28 alpha subunit Sulfotransfer_2 PF03567.14 CBY13889.1 - 1.1e-13 51.7 0.6 1.8e-13 51.0 0.6 1.2 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 CBY13889.1 - 0.00015 20.8 0.2 0.00067 18.7 0.2 1.8 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 CBY13889.1 - 0.049 13.1 0.1 0.13 11.8 0.1 1.7 1 1 0 1 1 1 0 Sulfotransferase domain UCR_UQCRX_QCR9 PF05365.12 CBY13890.1 - 0.0061 16.5 0.3 0.0088 16.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Pkinase PF00069.25 CBY13891.1 - 2.3e-38 132.1 0.0 3.1e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13891.1 - 1.1e-13 51.0 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY13891.1 - 2.2e-08 33.7 0.0 3.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY13891.1 - 4e-06 25.9 0.0 6.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY13891.1 - 0.00049 19.5 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY13891.1 - 0.00077 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY13891.1 - 0.0008 18.4 0.2 0.0017 17.4 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CBY13891.1 - 0.0015 18.2 0.2 0.0027 17.3 0.2 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase PilN_bio_d PF18222.1 CBY13891.1 - 0.012 16.0 0.1 0.048 14.1 0.0 1.9 2 0 0 2 2 2 0 PilN biogenesis protein dimerization domain PLAC8 PF04749.17 CBY13892.1 - 1.1e-21 77.7 13.6 1.2e-21 77.5 13.6 1.0 1 0 0 1 1 1 1 PLAC8 family TBPIP PF07106.13 CBY13893.1 - 1.1e-16 60.5 0.1 1.1e-16 60.5 0.1 2.2 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain DUF4407 PF14362.6 CBY13893.1 - 0.02 14.3 5.3 0.022 14.1 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLU_N PF15044.6 CBY13893.1 - 0.077 13.4 3.5 0.11 12.9 1.2 2.2 1 1 1 2 2 2 0 Mitochondrial function, CLU-N-term Atg14 PF10186.9 CBY13893.1 - 0.082 12.0 5.4 0.088 11.9 5.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ACT_5 PF13710.6 CBY13893.1 - 0.15 12.0 1.4 0.35 10.8 1.1 1.8 1 1 0 1 1 1 0 ACT domain DUF1732 PF08340.11 CBY13893.1 - 0.17 11.9 6.6 0.3 11.1 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) RdDM_RDM1 PF09187.10 CBY13893.1 - 0.23 11.5 1.4 1.4 9.0 0.1 2.0 1 1 1 2 2 2 0 RNA-directed DNA methylation 1 Thioredoxin_10 PF17991.1 CBY13893.1 - 0.24 11.9 2.8 0.42 11.2 0.7 1.9 1 1 1 2 2 2 0 Thioredoxin like C-terminal domain YabA PF06156.13 CBY13893.1 - 0.44 11.2 12.7 0.51 11.0 2.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA AAA_23 PF13476.6 CBY13893.1 - 0.47 10.9 10.0 0.69 10.4 10.0 1.2 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 CBY13893.1 - 0.56 10.6 12.9 4.1 7.8 1.9 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain LMBR1 PF04791.16 CBY13893.1 - 5.1 5.9 4.6 5.7 5.7 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 CBY13893.1 - 6.5 6.6 14.0 2.9 7.7 1.7 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 CBY13893.1 - 7.5 7.1 8.0 1.6e+02 2.8 7.9 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BST2 PF16716.5 CBY13894.1 - 0.95 10.1 9.7 3.3 8.3 4.7 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 ZapB PF06005.12 CBY13894.1 - 3.9 8.0 14.9 11 6.6 14.9 2.0 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 CBY13894.1 - 8.7 7.1 8.6 23 5.7 8.3 2.1 1 1 0 1 1 1 0 Initiation control protein YabA MAPEG PF01124.18 CBY13896.1 - 8.9e-21 74.2 0.3 1.1e-20 73.9 0.3 1.1 1 0 0 1 1 1 1 MAPEG family LysE PF01810.18 CBY13896.1 - 0.0014 18.1 0.6 0.32 10.4 0.1 2.3 1 1 1 2 2 2 2 LysE type translocator WD40 PF00400.32 CBY13897.1 - 2.1e-09 37.9 1.7 0.0064 17.3 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY13897.1 - 0.00063 20.0 0.0 5.5 7.4 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CBY13897.1 - 0.024 14.5 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat HU-CCDC81_bac_1 PF18174.1 CBY13897.1 - 0.061 13.2 0.1 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 1 PQQ_3 PF13570.6 CBY13897.1 - 0.18 12.4 0.0 1.5e+02 3.0 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain DUF4508 PF14969.6 CBY13898.1 - 1.4e-13 50.9 3.8 1.7e-13 50.6 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Cas9_a PF18470.1 CBY13898.1 - 0.017 14.7 2.2 2.9 7.4 0.8 2.0 1 1 0 2 2 2 0 Cas9 alpha-helical lobe domain Peptidase_S9 PF00326.21 CBY13899.1 - 8.7e-31 107.0 0.0 1.3e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CBY13899.1 - 4.4e-08 32.7 0.0 3.6e-06 26.4 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY13899.1 - 2.5e-06 27.3 1.1 4.5e-05 23.2 0.7 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 CBY13899.1 - 0.00053 19.6 0.0 0.002 17.7 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2920 PF11144.8 CBY13899.1 - 0.0079 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 CBY13899.1 - 0.013 15.3 0.0 0.042 13.7 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY13899.1 - 0.035 14.7 0.1 0.05 14.2 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 CBY13899.1 - 0.078 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AXE1 PF05448.12 CBY13899.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.28 CBY13899.1 - 0.32 9.8 1.2 4.1 6.2 0.1 2.0 2 0 0 2 2 2 0 Carboxylesterase family NDUF_B4 PF07225.12 CBY13900.1 - 0.045 13.6 0.0 0.054 13.4 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SNF2_N PF00176.23 CBY13901.1 - 2.8e-65 220.4 1.7 5e-65 219.5 1.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY13901.1 - 2e-22 79.6 0.0 1.7e-21 76.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CBY13901.1 - 1.5e-19 69.9 0.4 4e-19 68.5 0.1 1.9 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.6 CBY13901.1 - 2.4e-18 66.5 6.4 2.4e-18 66.5 6.4 4.3 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 CBY13901.1 - 4.7e-05 23.5 0.0 4.7e-05 23.5 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBY13901.1 - 0.0002 21.2 0.0 0.00058 19.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_8 PF12780.7 CBY13901.1 - 0.08 12.2 1.6 0.2 10.9 1.6 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 HSA PF07529.13 CBY13902.1 - 1.7e-13 50.7 14.6 1.7e-13 50.7 14.6 3.1 3 0 0 3 3 3 1 HSA QLQ PF08880.11 CBY13902.1 - 5.1e-11 42.1 5.1 1.3e-10 40.9 5.1 1.8 1 0 0 1 1 1 1 QLQ DPPIV_N PF00930.21 CBY13904.1 - 6.1e-43 146.9 8.6 1e-42 146.2 8.6 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CBY13904.1 - 3.1e-27 95.4 0.6 7e-27 94.3 0.6 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CBY13904.1 - 0.0012 19.4 0.1 0.0023 18.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CBY13904.1 - 0.046 13.5 0.1 0.46 10.2 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase NOD2_WH PF17779.1 CBY13904.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 NOD2 winged helix domain MalF_P2 PF14785.6 CBY13905.1 - 0.00063 19.8 0.7 0.0099 15.9 0.2 2.5 2 0 0 2 2 2 1 Maltose transport system permease protein MalF P2 domain ISK_Channel PF02060.15 CBY13905.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Cob_adeno_trans PF01923.18 CBY13905.1 - 0.78 9.9 3.7 1.1 9.3 0.2 2.7 2 1 2 4 4 4 0 Cobalamin adenosyltransferase DegS PF05384.11 CBY13905.1 - 7.8 6.0 13.7 1.3 8.5 0.9 4.1 5 0 0 5 5 5 0 Sensor protein DegS Pkinase PF00069.25 CBY13906.1 - 1.2e-50 172.3 0.0 1.5e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13906.1 - 3.1e-34 118.4 0.0 3.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBY13906.1 - 0.0006 19.5 0.1 0.32 10.6 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CBY13906.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY13906.1 - 0.012 15.6 0.0 4.8 7.0 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY13906.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Mucin PF01456.17 CBY13907.1 - 0.22 11.5 22.9 0.37 10.8 22.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Ndc1_Nup PF09531.10 CBY13907.1 - 0.27 9.9 1.0 0.25 10.0 1.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ASFV_J13L PF05568.11 CBY13907.1 - 8.2 6.1 11.1 13 5.4 11.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein CUB PF00431.20 CBY13908.1 - 9e-10 38.9 0.2 1.9e-09 37.8 0.2 1.5 1 0 0 1 1 1 1 CUB domain Adeno_E3_CR1 PF02440.15 CBY13908.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 AAA_23 PF13476.6 CBY13908.1 - 0.087 13.3 9.4 0.13 12.8 9.4 1.3 1 0 0 1 1 1 0 AAA domain ETRAMP PF09716.10 CBY13908.1 - 0.78 9.8 0.0 0.78 9.8 0.0 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) ZZ PF00569.17 CBY13910.1 - 1.5e-12 47.1 7.0 1.5e-12 47.1 7.0 2.6 3 1 0 3 3 3 1 Zinc finger, ZZ type Osmo_CC PF08946.10 CBY13910.1 - 0.12 12.6 4.6 0.26 11.6 4.6 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF4665 PF15679.5 CBY13910.1 - 0.64 10.7 4.6 1 10.0 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) CH PF00307.31 CBY13912.1 - 6.2e-16 58.5 0.0 1.2e-15 57.6 0.0 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CDC24 PF06395.11 CBY13912.1 - 0.0068 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 CBY13912.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain EXS PF03124.14 CBY13913.1 - 2.5e-76 257.2 23.2 3.4e-76 256.7 23.2 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CBY13913.1 - 2.3e-15 57.4 5.4 2.3e-15 57.4 5.4 2.2 1 1 1 2 2 2 2 SPX domain Trypsin PF00089.26 CBY13914.1 - 8.8e-53 179.4 6.0 1.1e-52 179.1 6.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY13914.1 - 9.9e-05 23.3 0.1 0.00021 22.2 0.1 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Zona_pellucida PF00100.23 CBY13914.1 - 0.0047 16.8 0.1 0.0085 15.9 0.1 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain DUF4423 PF14394.6 CBY13916.1 - 0.057 13.1 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Ephrin_lbd PF01404.19 CBY13917.1 - 0.029 14.4 0.1 0.032 14.3 0.1 1.0 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain BofC_C PF08955.10 CBY13917.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 BofC C-terminal domain Cupin_8 PF13621.6 CBY13919.1 - 2.3e-32 112.7 0.0 3e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY13919.1 - 5.4e-06 26.1 0.0 2.6e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 CBY13919.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Cupin JmjC PF02373.22 CBY13919.1 - 0.076 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase PS_Dcarbxylase PF02666.15 CBY13920.1 - 3.1e-64 216.2 0.0 4.4e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.22 CBY13920.1 - 0.097 12.9 0.0 11 6.3 0.0 2.8 2 1 1 3 3 3 0 Peptidase family M23 PRANC PF09372.10 CBY13921.1 - 0.026 14.8 0.2 0.085 13.2 0.2 1.9 1 1 0 1 1 1 0 PRANC domain IBN_N PF03810.19 CBY13921.1 - 0.064 13.2 0.8 1.2 9.1 0.0 2.8 2 1 0 2 2 2 0 Importin-beta N-terminal domain Put_Phosphatase PF06888.12 CBY13921.1 - 0.1 11.9 0.5 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase TSP_1 PF00090.19 CBY13922.1 - 5e-05 23.4 4.9 5e-05 23.4 4.9 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain CHGN PF05679.16 CBY13923.1 - 2e-92 310.7 4.1 2.4e-92 310.4 4.1 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY13923.1 - 5.8e-17 62.0 0.1 1.1e-16 61.0 0.1 1.5 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 CBY13923.1 - 1.3e-09 37.6 0.4 3.7e-09 36.1 0.4 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY13923.1 - 2.7e-05 24.0 0.1 0.043 13.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CBY13923.1 - 8.6e-05 22.1 0.1 0.034 13.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CBY13923.1 - 0.00041 19.9 0.0 0.42 10.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 21 Galactosyl_T PF01762.21 CBY13923.1 - 0.0014 18.4 0.0 0.057 13.2 0.0 2.6 2 0 0 2 2 2 1 Galactosyltransferase MRP_L53 PF10780.9 CBY13923.1 - 0.013 15.6 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 DUF4618 PF15397.6 CBY13923.1 - 0.013 14.9 0.3 0.028 13.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) PorA PF11271.8 CBY13925.1 - 0.12 11.7 1.4 7.7 5.7 0.1 2.2 2 0 0 2 2 2 0 Porin PorA zf-C2H2 PF00096.26 CBY13927.1 - 1.4e-07 31.5 6.7 0.0056 17.1 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 CBY13927.1 - 0.014 15.7 0.7 0.031 14.6 0.7 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CBY13927.1 - 0.015 15.7 0.3 0.015 15.7 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBY13927.1 - 0.026 14.3 0.7 0.026 14.3 0.7 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.7 CBY13927.1 - 0.063 13.7 1.0 0.17 12.3 1.0 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY13927.1 - 0.11 13.4 6.4 1.1 10.3 0.9 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBY13927.1 - 0.2 11.4 1.1 0.49 10.1 1.1 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain RXT2_N PF08595.11 CBY13927.1 - 0.68 10.0 7.7 0.5 10.4 3.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal zf-C2H2_2 PF12756.7 CBY13927.1 - 1.9 8.8 5.6 0.62 10.4 1.7 2.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) RVT_1 PF00078.27 CBY13928.1 - 6.2e-26 91.3 0.0 1.5e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CBY13928.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TANGO2 PF05742.12 CBY13931.1 - 1.8e-42 146.2 0.0 2.2e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Acyl-CoA_dh_1 PF00441.24 CBY13932.1 - 4.8e-49 166.4 3.9 7.7e-49 165.7 3.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY13932.1 - 1.4e-33 115.9 0.1 4.2e-33 114.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY13932.1 - 1.1e-26 92.9 0.1 2.2e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY13932.1 - 7.6e-23 81.3 3.7 1.4e-22 80.4 3.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBY13932.1 - 0.00016 21.4 0.3 0.00057 19.6 0.0 2.0 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF743 PF05332.11 CBY13932.1 - 0.013 15.6 0.2 0.024 14.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF743) Aldedh PF00171.22 CBY13933.1 - 2.3e-191 636.3 0.0 2.1e-148 494.7 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 CBY13933.1 - 0.00019 21.0 0.0 0.006 16.1 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1487) Adipokin_hormo PF06377.11 CBY13933.1 - 0.07 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Adipokinetic hormone BMC PF00936.19 CBY13933.1 - 0.082 12.9 0.2 18 5.4 0.0 2.7 2 0 0 2 2 2 0 BMC domain SspH PF08141.12 CBY13934.1 - 0.015 15.4 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Small acid-soluble spore protein H family Mobilization_B PF17511.2 CBY13934.1 - 0.1 12.9 0.8 0.18 12.2 0.8 1.4 1 0 0 1 1 1 0 Mobilization protein B YabA PF06156.13 CBY13934.1 - 0.34 11.6 16.5 0.11 13.1 1.6 3.0 1 1 2 3 3 3 0 Initiation control protein YabA Ntox28 PF15605.6 CBY13934.1 - 0.37 11.1 6.1 0.37 11.1 2.4 2.6 1 1 0 2 2 2 0 Bacterial toxin 28 HIP1_clath_bdg PF16515.5 CBY13934.1 - 0.75 10.4 20.9 1.7 9.3 3.7 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 bZIP_1 PF00170.21 CBY13934.1 - 1.5 9.0 21.3 0.74 9.9 2.2 3.8 3 2 0 3 3 3 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 CBY13934.1 - 1.5 9.0 22.0 5.2e+03 -2.5 22.0 2.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 GAS PF13851.6 CBY13934.1 - 2.2 7.6 24.2 0.45 9.8 5.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.6 CBY13934.1 - 3.1 8.2 16.9 13 6.2 6.3 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 TPR_MLP1_2 PF07926.12 CBY13934.1 - 3.1 7.8 22.9 83 3.2 18.3 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 CBY13934.1 - 3.4 8.2 25.1 3 8.4 6.4 3.4 2 1 1 3 3 3 0 Cell division protein ZapB Rootletin PF15035.6 CBY13934.1 - 4.4 7.3 21.9 22 5.0 3.3 2.9 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion VPS11_C PF12451.8 CBY13934.1 - 6.3 7.1 9.4 8.6 6.7 0.3 3.6 3 1 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal ADIP PF11559.8 CBY13934.1 - 7.7 6.6 21.5 3.6 7.7 12.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LUC7 PF03194.15 CBY13935.1 - 2e-73 247.1 13.5 2e-73 247.1 13.5 1.5 1 1 0 1 1 1 1 LUC7 N_terminus FidL_like PF15941.5 CBY13935.1 - 0.044 14.2 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 FidL-like putative membrane protein DUF1664 PF07889.12 CBY13935.1 - 0.18 11.8 4.7 0.14 12.1 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 CBY13935.1 - 0.21 11.9 4.5 1.5 9.1 0.2 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF1043 PF06295.12 CBY13935.1 - 0.74 9.8 4.3 5.1 7.1 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF16 PF01519.16 CBY13935.1 - 1.2 9.7 7.4 0.26 11.8 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 YtxH PF12732.7 CBY13935.1 - 6.4 7.4 6.3 18 6.0 4.3 2.5 2 1 0 2 2 2 0 YtxH-like protein Goodbye PF17109.5 CBY13935.1 - 9.7 6.7 7.8 0.43 11.0 1.2 2.1 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Ribosomal_S21e PF01249.18 CBY13936.1 - 1.1e-37 128.0 0.0 1.2e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ras PF00071.22 CBY13937.1 - 2.2e-20 72.9 0.1 2.6e-20 72.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY13937.1 - 0.0016 18.6 0.1 0.0059 16.8 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CBY13937.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B RRM_1 PF00076.22 CBY13938.1 - 6.2e-30 102.8 0.4 5.3e-12 45.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY13938.1 - 0.011 15.5 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 CBY13938.1 - 0.026 14.5 0.2 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 CBY13938.1 - 0.044 13.4 0.0 0.82 9.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4921 PF16268.5 CBY13939.1 - 0.099 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) ARL6IP6 PF15062.6 CBY13939.1 - 0.16 12.1 0.2 0.25 11.5 0.2 1.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Plectin PF00681.20 CBY13941.1 - 1.2e-107 351.6 17.7 1.6e-14 53.5 0.0 14.2 14 1 1 15 15 15 12 Plectin repeat I-set PF07679.16 CBY13942.1 - 1.5e-85 281.3 4.2 1.3e-11 44.4 0.0 8.9 8 1 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY13942.1 - 3.3e-50 168.6 0.0 9.1e-08 32.6 0.0 8.6 8 0 0 8 8 8 6 Immunoglobulin domain Ig_2 PF13895.6 CBY13942.1 - 6.9e-28 96.8 0.1 3.9e-06 27.1 0.0 7.9 8 1 0 8 8 8 5 Immunoglobulin domain ig PF00047.25 CBY13942.1 - 1.8e-20 72.9 1.6 0.028 14.6 0.0 7.6 8 0 0 8 8 8 6 Immunoglobulin domain V-set PF07686.17 CBY13942.1 - 2.6e-09 37.2 1.2 15 5.8 0.0 8.6 8 2 2 10 10 10 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY13942.1 - 0.0013 18.7 0.1 18 5.4 0.0 4.6 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 CBY13942.1 - 0.082 13.1 8.1 13 6.0 0.0 6.1 9 0 0 9 9 9 0 Natural killer cell receptor 2B4 Eapp_C PF10238.9 CBY13943.1 - 1.9 8.6 5.5 2.3 8.3 1.9 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein AP3D1 PF06375.11 CBY13943.1 - 3.3 7.9 12.1 1.2 9.4 2.4 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Peptidase_M17 PF00883.21 CBY13945.1 - 5e-111 370.9 0.1 1e-110 369.9 0.0 1.5 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CBY13945.1 - 3.4e-09 36.6 0.1 6e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Hira PF07569.11 CBY13945.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split GHMP_kinases_N PF00288.26 CBY13945.1 - 3.2 8.0 5.0 18 5.7 0.1 3.0 3 0 0 3 3 3 0 GHMP kinases N terminal domain NDUFB10 PF10249.9 CBY13946.1 - 8.3e-25 87.7 2.0 1.2e-24 87.3 2.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 VWA_2 PF13519.6 CBY13947.1 - 0.035 14.7 0.0 0.038 14.6 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain NAPRTase_N PF17767.1 CBY13947.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RP853 PF17542.2 CBY13949.1 - 0.0022 17.2 0.0 0.0022 17.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized RP853 DSPc PF00782.20 CBY13950.1 - 1.8e-24 86.1 0.5 2.6e-24 85.5 0.1 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBY13950.1 - 0.0052 16.8 0.1 0.007 16.4 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBY13950.1 - 0.019 15.1 3.2 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate z-alpha PF02295.17 CBY13950.1 - 0.2 11.8 1.5 0.41 10.7 1.5 1.5 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain Consortin_C PF15281.6 CBY13950.1 - 2.2 8.3 4.8 0.92 9.5 0.6 2.5 3 1 0 3 3 3 0 Consortin C-terminus Cyt-b5 PF00173.28 CBY13951.1 - 3.6e-10 39.8 0.1 6.6e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1604 PF07713.13 CBY13952.1 - 7.1e-30 102.7 4.9 1.5e-29 101.6 4.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 CBY13952.1 - 1.1e-05 25.2 0.9 0.00011 22.0 1.0 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CBY13952.1 - 0.008 16.2 1.1 0.008 16.2 1.1 2.8 2 1 0 2 2 2 1 G-patch domain NIPSNAP PF07978.13 CBY13954.1 - 6.8e-10 39.1 0.2 1.1e-05 25.6 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP Spa1_C PF18218.1 CBY13954.1 - 0.0076 16.6 0.8 0.012 16.0 0.4 1.5 2 0 0 2 2 2 1 Lantibiotic immunity protein Spa1 C-terminal domain FAD_SOX PF18371.1 CBY13956.1 - 0.031 14.6 0.1 0.056 13.8 0.1 1.4 1 1 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase CoA_binding PF02629.19 CBY13957.1 - 1.3e-28 99.5 1.3 1.3e-28 99.5 1.3 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CBY13957.1 - 3.6e-26 91.8 0.0 5.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CBY13957.1 - 3.1e-10 40.0 0.0 4.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBY13957.1 - 1.1e-05 25.9 0.1 3.4e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 CBY13957.1 - 0.079 13.8 0.1 0.19 12.5 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TCR PF03638.15 CBY13958.1 - 9.9e-26 89.8 53.6 1.8e-13 50.5 20.4 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 CBY13958.1 - 1.7 8.8 43.8 0.1 12.8 16.5 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 ATP-synt_S1 PF05827.12 CBY13959.1 - 0.0031 17.4 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Orthopox_A36R PF05950.11 CBY13959.1 - 0.24 11.6 1.7 0.3 11.2 0.5 1.7 2 0 0 2 2 2 0 Orthopoxvirus A36R protein Herpes_BLLF1 PF05109.13 CBY13960.1 - 0.53 8.2 17.4 0.57 8.1 17.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) FAP PF07174.11 CBY13960.1 - 4.4 6.7 16.6 5.5 6.4 16.6 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Pro_isomerase PF00160.21 CBY13961.1 - 5e-43 147.1 0.1 8e-43 146.4 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CBY13961.1 - 3.8e-18 65.1 0.0 6.7e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY13961.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif eIF-6 PF01912.18 CBY13962.1 - 3.7e-82 274.5 1.4 4.3e-82 274.3 1.0 1.3 2 0 0 2 2 2 1 eIF-6 family HU-CCDC81_bac_1 PF18174.1 CBY13963.1 - 0.015 15.2 0.1 0.055 13.3 0.0 1.9 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 1 DUF1398 PF07166.11 CBY13963.1 - 0.095 12.8 2.2 0.19 11.8 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1398) DHDPS PF00701.22 CBY13967.1 - 9.5e-43 145.9 0.0 1.1e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Mistic PF11458.8 CBY13967.1 - 0.15 12.0 0.0 0.6 10.1 0.0 2.0 1 0 0 1 1 1 0 Membrane-integrating protein Mistic ATP-gua_Ptrans PF00217.19 CBY13968.1 - 8.7e-62 208.4 0.0 1.1e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY13968.1 - 2.6e-24 85.4 0.0 5e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF840 PF05801.11 CBY13968.1 - 0.026 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) SL4P PF17618.2 CBY13968.1 - 0.049 13.7 0.0 0.86 9.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF5373 PF17343.2 CBY13970.1 - 0.011 15.6 0.0 0.011 15.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5373) ETRAMP PF09716.10 CBY13970.1 - 0.02 15.0 0.1 0.03 14.4 0.1 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) OapA_N PF08525.11 CBY13970.1 - 0.18 11.8 1.6 0.27 11.2 1.6 1.2 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif ATP-gua_Ptrans PF00217.19 CBY13972.1 - 1.1e-64 217.8 0.0 1.5e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY13972.1 - 2.5e-24 85.5 0.0 4.8e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF840 PF05801.11 CBY13972.1 - 0.025 14.7 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) SL4P PF17618.2 CBY13972.1 - 0.046 13.8 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein Sema PF01403.19 CBY13973.1 - 1.1e-06 27.7 4.1 1.5e-06 27.3 4.1 1.1 1 0 0 1 1 1 1 Sema domain ATP-gua_Ptrans PF00217.19 CBY13974.1 - 8.3e-65 218.2 0.0 1.1e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY13974.1 - 9.1e-25 86.8 0.0 1.8e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF840 PF05801.11 CBY13974.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) SL4P PF17618.2 CBY13974.1 - 0.051 13.6 0.0 0.84 9.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein Sema PF01403.19 CBY13975.1 - 4.2e-10 39.0 5.4 3.1e-08 32.9 5.4 2.2 1 1 0 1 1 1 1 Sema domain ASC PF00858.24 CBY13978.1 - 5.9e-17 61.8 11.2 7.9e-17 61.3 11.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel VWA PF00092.28 CBY13979.1 - 1.8e-22 80.4 0.1 4.2e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY13979.1 - 2.3e-17 63.6 0.1 1.8e-15 57.5 0.0 2.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Serglycin PF04360.12 CBY13979.1 - 0.0021 18.0 0.1 0.0054 16.7 0.0 1.7 2 0 0 2 2 2 1 Serglycin SBF PF01758.16 CBY13980.1 - 2.7e-27 95.7 15.0 3.7e-27 95.3 15.0 1.1 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 CBY13980.1 - 1.6e-10 40.9 11.8 2.1e-10 40.4 11.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 CBY13980.1 - 0.27 9.6 12.6 0.13 10.6 9.6 1.7 1 1 1 2 2 2 0 Membrane transport protein CBP_BcsF PF11120.8 CBY13980.1 - 0.58 10.3 3.6 0.58 10.3 0.7 2.3 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF PHO4 PF01384.20 CBY13981.1 - 0.037 13.1 0.1 0.04 13.0 0.1 1.1 1 0 0 1 1 1 0 Phosphate transporter family DUF1275 PF06912.11 CBY13981.1 - 0.069 13.1 1.8 0.11 12.4 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Acyltransferase PF01553.21 CBY13982.1 - 1.3e-14 54.0 0.0 2.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF3452 PF11934.8 CBY13982.1 - 0.052 13.1 0.7 0.11 12.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) YchF-GTPase_C PF06071.13 CBY13983.1 - 0.081 13.1 0.4 0.15 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Pkinase PF00069.25 CBY13984.1 - 5.4e-39 134.1 0.1 9.5e-39 133.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY13984.1 - 5.7e-28 97.9 0.0 9.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY13984.1 - 5.8e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FAD_binding_8 PF08022.12 CBY13984.1 - 0.0075 16.3 0.0 0.039 14.1 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain DUF2645 PF10840.8 CBY13984.1 - 0.12 13.0 0.1 0.3 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) Dehydrin PF00257.19 CBY13985.1 - 0.0027 18.3 0.6 0.0047 17.5 0.6 1.4 1 0 0 1 1 1 1 Dehydrin TPPII_N PF12583.8 CBY13985.1 - 0.21 12.2 5.0 0.77 10.3 5.0 1.9 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Homeodomain PF00046.29 CBY13986.1 - 2.6e-18 65.6 1.9 4.2e-18 64.9 1.9 1.3 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 CBY13986.1 - 3.3e-11 43.2 14.6 6e-08 32.8 5.0 2.4 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.11 CBY13986.1 - 1.2e-05 25.1 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF2175 PF09943.9 CBY13986.1 - 0.0029 17.9 5.5 0.17 12.2 1.7 2.6 1 1 1 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2175) DUF2685 PF10886.8 CBY13986.1 - 0.006 16.7 1.4 0.038 14.2 0.6 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2685) MFS_1 PF07690.16 CBY13988.1 - 2.4e-20 72.8 49.3 1.1e-12 47.6 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 CBY13988.1 - 2.7 8.5 6.2 25 5.4 0.6 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Trypsin PF00089.26 CBY13989.1 - 4.8e-50 170.4 1.9 6.9e-50 169.9 1.9 1.2 1 0 0 1 1 1 1 Trypsin Zip PF02535.22 CBY13991.1 - 0.69 9.1 2.5 0.7 9.0 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter KH_1 PF00013.29 CBY13992.1 - 7.5e-27 92.9 1.7 2.5e-13 49.6 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBY13992.1 - 4.6e-09 36.0 5.4 6.4e-05 22.7 0.8 2.3 1 1 1 2 2 2 2 KH domain KH_4 PF13083.6 CBY13992.1 - 3.3e-08 33.3 0.5 0.0092 15.8 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CBY13992.1 - 0.00036 20.6 0.9 0.29 11.3 0.0 2.6 2 1 0 2 2 2 2 NusA-like KH domain Med13_C PF06333.12 CBY13992.1 - 2 7.6 5.9 0.14 11.4 0.2 1.8 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain DUF4562 PF15123.6 CBY13993.1 - 4e-11 42.9 0.0 4.6e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) Lectin_C PF00059.21 CBY13996.1 - 7.6e-06 26.6 2.5 1.3e-05 25.9 2.5 1.4 1 1 0 1 1 1 1 Lectin C-type domain SCP2 PF02036.17 CBY13997.1 - 0.14 12.7 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 SCP-2 sterol transfer family RhoGEF PF00621.20 CBY13999.1 - 3.8e-32 112.0 10.2 3.8e-32 112.0 10.2 2.0 2 0 0 2 2 2 1 RhoGEF domain SH2 PF00017.24 CBY13999.1 - 8.6e-10 38.6 0.1 2.7e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 SH2 domain Amidase_2 PF01510.25 CBY14000.1 - 3.4e-13 50.1 0.2 4.7e-13 49.7 0.2 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Homeodomain PF00046.29 CBY14001.1 - 1.3e-20 72.9 3.1 2.4e-20 72.1 3.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY14001.1 - 0.0063 16.4 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 CBY14001.1 - 0.11 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF5068 PF16781.5 CBY14001.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) Kri1 PF05178.12 CBY14002.1 - 0.026 15.1 4.2 0.041 14.4 4.2 1.3 1 0 0 1 1 1 0 KRI1-like family LPP20 PF02169.16 CBY14002.1 - 0.43 10.9 4.7 0.79 10.1 4.7 1.5 1 1 0 1 1 1 0 LPP20 lipoprotein MFS_1 PF07690.16 CBY14005.1 - 3.2e-15 55.9 1.1 3.2e-15 55.9 1.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily CpeS PF09367.10 CBY14006.1 - 0.0066 16.4 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 2 CpeS-like protein DUF1246 PF06849.12 CBY14006.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) SET PF00856.28 CBY14007.1 - 4.8e-08 33.6 0.4 1.4e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 CBY14007.1 - 0.0073 17.0 0.3 0.015 16.0 0.3 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding OB_RNB PF08206.11 CBY14007.1 - 0.11 12.2 0.3 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain TAN PF11640.8 CBY14007.1 - 0.22 11.7 2.4 2.5 8.2 0.3 2.2 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair Imm7 PF15585.6 CBY14007.1 - 0.45 10.8 2.4 0.69 10.2 0.5 2.2 2 1 0 3 3 3 0 Immunity protein 7 SPRY PF00622.28 CBY14008.1 - 1.2e-08 35.1 0.0 5.2e-08 33.0 0.0 2.1 2 1 0 2 2 2 1 SPRY domain SOCS_box PF07525.16 CBY14008.1 - 8e-07 29.3 0.9 2.1e-06 28.0 0.9 1.7 1 0 0 1 1 1 1 SOCS box OLF PF02191.16 CBY14009.1 - 8.6e-78 261.3 6.5 1.1e-77 260.9 6.5 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Mif2_N PF15624.6 CBY14010.1 - 0.027 15.2 3.8 0.041 14.6 3.8 1.3 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal RPEL PF02755.15 CBY14011.1 - 6.9e-15 54.2 1.1 1.2e-07 31.1 0.1 2.3 2 0 0 2 2 2 2 RPEL repeat ASC PF00858.24 CBY14013.1 - 3.9e-09 36.0 6.6 4.1e-09 35.9 6.6 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 CBY14014.1 - 5.6e-08 32.2 0.1 7.4e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel GCIP PF13324.6 CBY14014.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting SH3_1 PF00018.28 CBY14015.1 - 3.7e-18 64.8 0.0 8.5e-11 41.3 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CBY14015.1 - 3.3e-17 62.1 0.0 1.8e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CBY14015.1 - 8.4e-13 47.8 0.0 2.5e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain DUF1402 PF07182.11 CBY14015.1 - 0.013 14.6 0.9 0.068 12.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1402) HORMA PF02301.18 CBY14016.1 - 3.6e-11 43.1 1.4 4.5e-11 42.8 1.4 1.1 1 0 0 1 1 1 1 HORMA domain BsuBI_PstI_RE PF06616.11 CBY14016.1 - 0.055 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain bacHORMA_1 PF18138.1 CBY14016.1 - 0.077 12.9 0.2 0.31 10.9 0.0 1.9 1 1 1 2 2 2 0 Bacterial HORMA domain family 1 KH_10 PF17905.1 CBY14016.1 - 0.086 13.3 0.5 0.23 11.9 0.2 1.9 2 0 0 2 2 2 0 GLD-3 KH domain 5 DUF3435 PF11917.8 CBY14017.1 - 0.071 12.0 1.2 0.28 10.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) Ribosomal_L7Ae PF01248.26 CBY14019.1 - 6.9e-24 83.4 0.3 1.1e-23 82.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CBY14019.1 - 0.0096 16.0 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Slp PF03843.13 CBY14019.1 - 0.037 13.4 0.4 0.7 9.3 0.1 2.1 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family Metal_resist PF13801.6 CBY14019.1 - 0.87 9.8 9.5 0.044 14.0 3.5 1.9 2 1 0 2 2 2 0 Heavy-metal resistance Peptidase_S49_N PF08496.10 CBY14019.1 - 4.3 7.4 7.5 1.7 8.7 1.8 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_S17e PF00833.18 CBY14020.1 - 2.5e-58 195.3 1.1 2.8e-58 195.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 PIN PF01850.21 CBY14020.1 - 0.053 14.0 0.3 0.075 13.5 0.3 1.2 1 0 0 1 1 1 0 PIN domain Tfb4 PF03850.14 CBY14022.1 - 1.8e-55 188.4 0.8 3.7e-55 187.4 0.8 1.4 1 1 0 1 1 1 1 Transcription factor Tfb4 Xpo1 PF08389.12 CBY14023.1 - 1.6e-27 96.4 1.8 1.8e-26 93.0 0.0 3.4 4 0 0 4 4 4 1 Exportin 1-like protein SRP14 PF02290.15 CBY14023.1 - 0.052 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Microtub_bd PF16796.5 CBY14023.1 - 0.07 13.1 0.3 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 Microtubule binding Proteasome PF00227.26 CBY14025.1 - 1.2e-48 165.2 0.0 1.5e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBY14025.1 - 6.4e-13 48.1 0.0 1.1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_L30_N PF08079.12 CBY14026.1 - 4.6e-05 23.6 9.7 4.6e-05 23.6 9.7 1.9 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain YhdB PF14148.6 CBY14026.1 - 0.041 14.0 0.2 0.52 10.4 0.0 2.6 2 1 0 2 2 2 0 YhdB-like protein Ribosomal_L30 PF00327.20 CBY14026.1 - 0.047 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e DUF3510 PF12022.8 CBY14026.1 - 0.1 13.0 1.4 0.21 12.0 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Ribosomal_L32e PF01655.18 CBY14027.1 - 1.3e-44 151.1 2.1 1.6e-44 150.8 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L32e PF01655.18 CBY14029.1 - 1.1e-39 135.2 0.7 1.3e-39 134.9 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase PF00069.25 CBY14031.1 - 0.044 13.1 0.2 0.057 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein kinase domain Aldo_ket_red PF00248.21 CBY14032.1 - 9.4e-48 162.9 0.0 1.4e-47 162.3 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family LIM PF00412.22 CBY14034.1 - 8.9e-18 64.3 25.5 1.1e-09 38.4 5.7 2.8 3 0 0 3 3 3 2 LIM domain Homeodomain PF00046.29 CBY14034.1 - 3.8e-17 61.9 5.9 9.4e-17 60.6 5.9 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY14034.1 - 9.4e-05 22.2 0.1 0.00024 20.9 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Nup54 PF13874.6 CBY14034.1 - 0.0092 16.1 1.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 zf-PARP PF00645.18 CBY14034.1 - 0.011 16.6 3.0 0.04 14.8 2.9 2.1 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DZR PF12773.7 CBY14034.1 - 0.011 15.7 15.0 0.34 11.0 2.5 3.6 1 1 2 3 3 3 0 Double zinc ribbon DUF2175 PF09943.9 CBY14034.1 - 0.067 13.5 0.8 0.067 13.5 0.8 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Macoilin PF09726.9 CBY14034.1 - 0.81 8.2 11.5 1 7.8 11.5 1.1 1 0 0 1 1 1 0 Macoilin family zf-RING_2 PF13639.6 CBY14034.1 - 6.8 7.1 18.6 3.1 8.2 0.5 4.6 3 1 1 4 4 4 0 Ring finger domain IGFBP PF00219.18 CBY14034.1 - 9.9 6.9 13.4 0.38 11.4 3.6 2.9 1 1 1 2 2 2 0 Insulin-like growth factor binding protein TSP_1 PF00090.19 CBY14035.1 - 3.7e-154 500.9 417.3 1.7e-08 34.6 8.5 25.3 24 1 1 25 25 25 25 Thrombospondin type 1 domain TSP_1 PF00090.19 CBY14036.1 - 1e-18 67.2 53.9 1.5e-06 28.3 7.4 4.6 3 1 1 4 4 4 4 Thrombospondin type 1 domain VWA PF00092.28 CBY14036.1 - 5.9e-13 49.4 0.0 7.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 CBY14036.1 - 0.018 15.3 9.0 0.018 15.3 9.0 4.9 5 2 0 5 5 5 0 Coagulation Factor Xa inhibitory site TSP_1 PF00090.19 CBY14037.1 - 2e-95 312.9 244.8 1.9e-10 40.8 6.1 15.4 15 0 0 15 15 15 15 Thrombospondin type 1 domain VWA PF00092.28 CBY14037.1 - 2.3e-12 47.5 0.0 3.1e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-3CxxC_2 PF17180.4 CBY14040.1 - 2.8e-23 82.4 7.1 2.8e-23 82.4 7.1 3.9 3 2 1 4 4 4 1 Zinc-binding domain zf-DBF PF07535.12 CBY14040.1 - 0.087 13.0 1.3 0.087 13.0 1.3 2.7 2 0 0 2 2 2 0 DBF zinc finger Zn-ribbon_8 PF09723.10 CBY14040.1 - 2.7 8.2 36.8 0.99 9.6 2.0 5.0 5 0 0 5 5 5 0 Zinc ribbon domain Carn_acyltransf PF00755.20 CBY14041.1 - 1.3e-08 33.9 0.0 1.5e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Connexin PF00029.19 CBY14042.1 - 2.1e-65 220.7 6.0 2.5e-65 220.5 6.0 1.1 1 0 0 1 1 1 1 Connexin Na_H_antiporter PF03553.14 CBY14042.1 - 0.013 14.7 2.4 2.3 7.4 0.1 2.5 3 0 0 3 3 3 0 Na+/H+ antiporter family CLN3 PF02487.17 CBY14042.1 - 0.025 13.6 0.8 0.035 13.2 0.8 1.2 1 0 0 1 1 1 0 CLN3 protein DUF1980 PF09323.10 CBY14042.1 - 0.11 12.4 2.2 0.71 9.8 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) UPF0242 PF06785.11 CBY14042.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.7 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus UPF0239 PF06783.11 CBY14042.1 - 5.4 7.3 9.0 0.11 12.7 0.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) 60KD_IMP PF02096.20 CBY14042.1 - 6.7 6.6 14.4 20 5.1 10.9 2.5 2 1 0 2 2 2 0 60Kd inner membrane protein Ilar_coat PF01787.16 CBY14043.1 - 0.034 14.0 0.5 0.063 13.1 0.5 1.4 1 0 0 1 1 1 0 Ilarvirus coat protein Phospholip_A2_1 PF00068.19 CBY14044.1 - 2.1e-11 44.3 0.1 2.1e-11 44.3 0.1 1.9 2 0 0 2 2 2 1 Phospholipase A2 DUF5001 PF16392.5 CBY14045.1 - 0.0042 17.0 0.3 0.016 15.1 0.1 1.9 2 0 0 2 2 2 1 Ig-like domain CCDC142 PF14923.6 CBY14046.1 - 8.9e-13 47.8 0.7 1.1e-12 47.5 0.7 1.1 1 0 0 1 1 1 1 Coiled-coil protein 142 HAUS5 PF14817.6 CBY14046.1 - 0.00016 20.6 0.5 0.0002 20.3 0.5 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Virul_Fac PF10139.9 CBY14046.1 - 0.055 11.7 2.3 0.28 9.3 0.7 2.0 1 1 1 2 2 2 0 Putative bacterial virulence factor E3_UFM1_ligase PF09743.9 CBY14047.1 - 2.8e-74 250.2 3.4 6.3e-74 249.0 2.9 1.9 1 1 0 1 1 1 1 E3 UFM1-protein ligase 1 MRP-S27 PF10037.9 CBY14047.1 - 1.1e-15 57.5 0.0 1.1e-15 57.5 0.0 4.0 3 1 1 4 4 4 1 Mitochondrial 28S ribosomal protein S27 TrmB PF01978.19 CBY14047.1 - 0.0045 16.9 0.0 0.24 11.3 0.0 3.2 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB FliN_N PF16973.5 CBY14047.1 - 0.072 12.9 1.5 0.15 11.9 0.5 2.1 2 0 0 2 2 2 0 Flagellar motor switch protein FliN N-terminal eIF3_subunit PF08597.10 CBY14048.1 - 5.3e-30 105.1 22.0 6.1e-30 104.9 22.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Paz_1 PF18349.1 CBY14048.1 - 4.2 7.4 7.8 0.76 9.8 3.7 1.8 2 0 0 2 2 2 0 PAZ domain Usp PF00582.26 CBY14048.1 - 6.9 7.2 7.9 11 6.5 7.9 1.3 1 0 0 1 1 1 0 Universal stress protein family Presenilin PF01080.17 CBY14048.1 - 9.2 4.9 5.8 8.6 5.0 5.8 1.2 1 0 0 1 1 1 0 Presenilin Ran_BP1 PF00638.18 CBY14049.1 - 2.7e-12 47.0 0.0 9e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 RanBP1 domain MH1 PF03165.16 CBY14050.1 - 0.0025 18.0 0.1 0.0045 17.2 0.1 1.4 1 0 0 1 1 1 1 MH1 domain MH2 PF03166.14 CBY14051.1 - 1.3e-63 214.6 1.2 2e-63 214.0 1.2 1.3 1 0 0 1 1 1 1 MH2 domain MH2 PF03166.14 CBY14052.1 - 6.7e-33 114.5 0.1 1.3e-32 113.5 0.1 1.5 1 0 0 1 1 1 1 MH2 domain Arfaptin PF06456.13 CBY14053.1 - 1.8e-45 155.3 12.8 2.6e-45 154.8 12.8 1.1 1 0 0 1 1 1 1 Arfaptin-like domain PKHD_C PF18331.1 CBY14053.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain RRM_1 PF00076.22 CBY14054.1 - 4.6e-08 32.8 0.0 1.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MSP1b PF03429.13 CBY14055.1 - 0.021 12.9 0.0 0.025 12.7 0.0 1.0 1 0 0 1 1 1 0 Major surface protein 1B DUF1509 PF07420.11 CBY14055.1 - 1.7 7.5 15.2 2.2 7.2 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Pns11_12 PF17464.2 CBY14055.1 - 3.9 7.1 19.1 3.6 7.3 17.8 1.5 1 1 1 2 2 2 0 Non-structural protein 11 and 12 Gag_p12 PF01141.18 CBY14056.1 - 0.72 10.2 5.5 0.48 10.8 0.4 2.4 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Pkinase PF00069.25 CBY14057.1 - 3.9e-69 232.9 0.0 4.5e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14057.1 - 1.6e-31 109.5 0.0 2e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY14057.1 - 0.00075 18.9 0.0 0.0018 17.6 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CBY14057.1 - 0.0021 17.2 0.1 0.0035 16.5 0.1 1.3 1 1 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CBY14057.1 - 0.011 14.7 0.0 0.051 12.5 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBY14057.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CBY14057.1 - 0.16 11.3 0.1 0.54 9.6 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SLC12 PF03522.15 CBY14060.1 - 4.2e-11 42.5 0.0 4.6e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Solute carrier family 12 GMC_oxred_C PF05199.13 CBY14061.1 - 2.7e-15 57.2 0.6 3.4e-15 56.8 0.6 1.2 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.16 CBY14062.1 - 4e-31 108.2 30.0 3.1e-20 72.4 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CBY14062.1 - 4.2e-05 23.0 13.5 0.0046 16.3 0.9 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Gram_pos_anchor PF00746.21 CBY14062.1 - 0.74 9.8 3.5 1.1 9.3 0.1 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif GATA PF00320.27 CBY14063.1 - 0.032 13.9 1.1 0.07 12.7 1.1 1.5 1 0 0 1 1 1 0 GATA zinc finger YlqD PF11068.8 CBY14063.1 - 0.074 13.4 0.2 0.074 13.4 0.2 5.4 3 1 2 6 6 6 0 YlqD protein Siva PF05458.12 CBY14063.1 - 0.082 12.6 2.0 0.17 11.5 0.1 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Apo-CIII PF05778.12 CBY14064.1 - 0.0099 15.5 0.2 0.033 13.8 0.2 1.9 1 0 0 1 1 1 1 Apolipoprotein CIII (Apo-CIII) TFIIS_M PF07500.14 CBY14066.1 - 0.00044 20.7 0.4 0.00044 20.7 0.4 2.5 2 2 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain DAPDH_C PF16654.5 CBY14066.1 - 0.16 11.8 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain CUT PF02376.15 CBY14067.1 - 7.1e-32 109.4 0.1 1.2e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 CUT domain Myf5 PF12232.8 CBY14067.1 - 0.043 14.6 3.5 0.043 14.6 3.5 1.7 2 0 0 2 2 2 0 Myogenic determination factor 5 zf-LITAF-like PF10601.9 CBY14068.1 - 0.0056 16.9 3.6 0.006 16.8 3.6 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain bZIP_2 PF07716.15 CBY14070.1 - 0.064 13.3 1.5 0.24 11.5 1.5 1.9 1 0 0 1 1 1 0 Basic region leucine zipper Chlam_PMP PF02415.17 CBY14070.1 - 0.075 13.5 0.9 0.33 11.5 0.0 2.6 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TIL PF01826.17 CBY14071.1 - 6.8e-26 90.3 153.3 6.2e-10 39.2 15.5 8.4 6 2 1 7 7 7 5 Trypsin Inhibitor like cysteine rich domain TMEM208_SND2 PF05620.11 CBY14072.1 - 0.0074 16.1 1.8 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 SRP-independent targeting protein 2/TMEM208 DUF3624 PF12292.8 CBY14072.1 - 0.024 15.0 0.4 0.052 14.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) MBOAT PF03062.19 CBY14073.1 - 5.8e-12 45.6 12.6 1.1e-11 44.7 12.5 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Zip PF02535.22 CBY14074.1 - 9.3e-12 44.8 8.2 6.1e-11 42.1 8.1 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter HAS-barrel PF09378.10 CBY14074.1 - 0.044 13.9 0.3 0.1 12.8 0.3 1.5 1 0 0 1 1 1 0 HAS barrel domain Hid1 PF12722.7 CBY14074.1 - 1.1 7.3 3.8 1.4 7.0 3.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Astacin PF01400.24 CBY14075.1 - 2e-22 79.8 0.2 3.4e-21 75.7 0.2 2.5 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_3 PF12947.7 CBY14075.1 - 0.00046 20.3 16.2 0.00083 19.5 5.1 10.6 11 0 0 11 11 11 3 EGF domain EGF_CA PF07645.15 CBY14075.1 - 0.00078 19.6 5.3 0.00078 19.6 5.3 9.5 8 1 0 8 8 8 4 Calcium-binding EGF domain RasGEF PF00617.19 CBY14076.1 - 5.2e-43 147.3 0.3 7.4e-42 143.5 0.0 2.1 1 1 1 2 2 2 1 RasGEF domain PH PF00169.29 CBY14076.1 - 7.9e-05 23.1 0.2 0.00014 22.3 0.2 1.4 1 0 0 1 1 1 1 PH domain Cyclin_N PF00134.23 CBY14077.1 - 4.7e-16 58.7 2.7 3e-10 39.9 0.0 2.6 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY14077.1 - 8.6e-06 25.8 0.2 2.6e-05 24.3 0.2 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 CBY14077.1 - 0.0038 17.6 0.1 0.013 15.9 0.1 1.9 1 1 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 CBY14077.1 - 0.0093 16.0 0.1 3.1 7.9 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat PRP38_assoc PF12871.7 CBY14077.1 - 6 7.5 72.6 0.053 14.1 49.2 2.3 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RSRP PF17069.5 CBY14077.1 - 6.5 6.2 43.9 9 5.8 43.9 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 WD40 PF00400.32 CBY14078.1 - 3.8e-20 71.8 5.1 0.00014 22.6 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ATG16 PF08614.11 CBY14078.1 - 1.6e-17 64.4 23.6 2.5e-17 63.8 23.6 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ANAPC4_WD40 PF12894.7 CBY14078.1 - 3.8e-09 36.7 0.3 0.13 12.6 0.0 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain FlxA PF14282.6 CBY14078.1 - 0.00059 19.8 4.8 0.00059 19.8 4.8 2.2 2 0 0 2 2 2 1 FlxA-like protein Ge1_WD40 PF16529.5 CBY14078.1 - 0.002 17.2 0.3 0.12 11.3 0.0 3.7 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY14078.1 - 0.0049 15.6 3.8 0.42 9.2 0.5 2.9 2 2 0 3 3 3 2 Nucleoporin Nup120/160 EzrA PF06160.12 CBY14078.1 - 0.0094 14.2 18.2 0.017 13.3 18.2 1.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA WD40_like PF17005.5 CBY14078.1 - 0.042 13.2 0.0 0.43 9.9 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain APC_N_CC PF16689.5 CBY14078.1 - 0.047 13.8 0.5 0.047 13.8 0.5 3.3 4 0 0 4 4 3 0 Coiled-coil N-terminus of APC, dimerisation domain PD40 PF07676.12 CBY14078.1 - 0.084 12.8 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TFA2_Winged_2 PF18121.1 CBY14078.1 - 0.15 11.8 1.3 1 9.1 0.6 2.8 3 1 0 3 3 3 0 TFA2 Winged helix domain 2 Miga PF10265.9 CBY14078.1 - 1.9 7.3 11.1 2.8 6.8 11.1 1.2 1 0 0 1 1 1 0 Mitoguardin DUF1664 PF07889.12 CBY14078.1 - 2.5 8.1 6.6 9.2 6.3 0.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 CBY14078.1 - 2.7 7.2 13.6 1.2 8.4 5.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 CBY14078.1 - 3.4 7.7 22.8 0.17 11.9 14.4 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 CBY14078.1 - 5.4 7.2 16.9 0.81 9.8 1.9 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 CBY14078.1 - 6.1 6.6 13.8 26 4.6 13.0 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF724) WEMBL PF05701.11 CBY14079.1 - 0.002 16.9 4.6 0.003 16.4 4.6 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ABC_tran_CTD PF16326.5 CBY14079.1 - 0.0029 17.8 1.8 0.17 12.1 0.2 2.5 2 0 0 2 2 2 1 ABC transporter C-terminal domain Mce4_CUP1 PF11887.8 CBY14079.1 - 0.069 12.6 0.3 0.1 12.0 0.3 1.1 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative GAS PF13851.6 CBY14079.1 - 0.1 11.9 7.1 0.46 9.8 7.1 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 CBY14079.1 - 0.15 10.2 8.3 0.022 13.0 4.8 1.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Ureide_permease PF07168.11 CBY14079.1 - 0.21 10.3 2.2 0.26 10.0 0.1 1.8 1 1 1 2 2 2 0 Ureide permease Fez1 PF06818.15 CBY14079.1 - 0.3 11.5 5.6 0.54 10.7 5.6 1.4 1 0 0 1 1 1 0 Fez1 LMBR1 PF04791.16 CBY14079.1 - 0.37 9.7 1.4 0.4 9.5 1.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Prominin PF05478.11 CBY14079.1 - 0.56 8.1 6.1 0.73 7.7 6.1 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 CBY14079.1 - 1.1 9.3 7.2 0.39 10.8 1.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 CBY14079.1 - 1.1 9.8 8.8 0.29 11.7 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 CBY14079.1 - 1.1 8.8 6.2 2.2 7.8 1.0 2.3 1 1 1 2 2 2 0 fzo-like conserved region DUF948 PF06103.11 CBY14079.1 - 1.9 8.8 5.3 2.8 8.3 0.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.17 CBY14079.1 - 2.4 8.1 11.0 2.4 8.1 0.7 3.5 2 1 0 3 3 3 0 Prefoldin subunit FapA PF03961.13 CBY14079.1 - 4.6 5.7 9.1 35 2.8 9.0 2.1 1 1 0 1 1 1 0 Flagellar Assembly Protein A FliD_N PF02465.18 CBY14079.1 - 6 7.6 6.9 1e+02 3.7 6.9 2.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Golgin_A5 PF09787.9 CBY14080.1 - 2.5e-58 197.9 26.9 2.5e-58 197.9 26.9 2.4 1 1 1 2 2 2 1 Golgin subfamily A member 5 UreE_N PF02814.15 CBY14080.1 - 0.24 11.0 3.1 0.25 11.0 1.0 2.1 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain BSD PF03909.17 CBY14080.1 - 1.3 9.1 8.3 28 4.8 0.0 4.1 3 1 1 4 4 4 0 BSD domain ELO PF01151.18 CBY14081.1 - 2.9e-50 171.1 16.5 3.5e-50 170.9 16.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MerC PF03203.14 CBY14081.1 - 0.077 13.4 6.7 1.9 8.9 3.3 2.6 1 1 1 2 2 2 0 MerC mercury resistance protein CBM_14 PF01607.24 CBY14082.1 - 1e-29 102.4 17.2 2.6e-15 56.3 4.4 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Baculo_VP91_N PF08475.10 CBY14082.1 - 0.44 10.2 3.8 0.44 10.2 0.6 1.9 1 1 1 2 2 2 0 Viral capsid protein 91 N-terminal DUF5401 PF17380.2 CBY14082.1 - 1.1 7.3 5.5 3.4 5.6 1.5 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5401) PIH1 PF08190.12 CBY14083.1 - 2.8e-30 105.0 0.1 5.7e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CBY14083.1 - 9.5e-09 35.6 0.1 2.5e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain NTP_transferase PF00483.23 CBY14084.1 - 1.2e-20 74.1 0.0 4.1e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CBY14084.1 - 5.5e-11 43.1 0.0 6.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 CBY14084.1 - 9.3e-05 22.3 0.0 0.0012 18.6 0.0 2.2 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pkinase PF00069.25 CBY14085.1 - 2e-61 207.7 0.0 5.1e-60 203.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14085.1 - 6.6e-25 87.9 0.0 1.7e-23 83.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY14085.1 - 4.3e-07 29.5 0.0 2.7e-06 26.9 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CBY14085.1 - 0.00049 19.2 0.0 0.0083 15.1 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBY14085.1 - 0.0048 16.9 0.2 0.016 15.1 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY14085.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 CBY14085.1 - 0.0083 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBY14085.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBY14085.1 - 0.11 12.1 0.1 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SfsA PF03749.13 CBY14085.1 - 0.11 12.4 0.1 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Sugar fermentation stimulation protein RE domain CHGN PF05679.16 CBY14086.1 - 2.9e-142 475.1 0.0 3.5e-142 474.8 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase AhpC-TSA PF00578.21 CBY14087.1 - 1.3e-39 134.9 0.0 5e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CBY14087.1 - 6.5e-17 61.6 0.0 8.6e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBY14087.1 - 4.8e-13 48.7 0.1 8.2e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CBY14087.1 - 0.025 14.5 0.1 0.055 13.4 0.0 1.5 2 0 0 2 2 2 0 SCO1/SenC Ssl1 PF04056.14 CBY14088.1 - 1.8e-43 148.6 0.0 2.4e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CBY14088.1 - 4.9e-08 33.6 0.0 1.2e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 CBY14088.1 - 2.9e-05 24.2 13.0 0.00011 22.3 13.1 2.0 1 1 1 2 2 2 1 TFIIH C1-like domain IBR PF01485.21 CBY14088.1 - 0.071 13.3 2.8 0.17 12.1 2.8 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ADH_zinc_N PF00107.26 CBY14089.1 - 9.2e-22 77.4 0.1 1.8e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBY14089.1 - 6.4e-08 32.5 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 CBY14089.1 - 0.056 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_kinase PF01513.21 CBY14090.1 - 1.1e-64 218.4 0.0 1.4e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CBY14090.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Cauli_VI PF01693.16 CBY14091.1 - 2.3e-34 117.5 10.7 6.2e-18 64.8 0.7 3.3 3 0 0 3 3 3 2 Caulimovirus viroplasmin RNase_H PF00075.24 CBY14091.1 - 2.6e-27 95.8 0.1 5.5e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CBY14091.1 - 0.0047 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like Brix PF04427.18 CBY14092.1 - 1.3e-38 133.0 0.1 1.9e-38 132.5 0.1 1.2 1 0 0 1 1 1 1 Brix domain Cation_efflux PF01545.21 CBY14093.1 - 3.4e-28 98.7 8.2 4.2e-28 98.5 8.2 1.1 1 0 0 1 1 1 1 Cation efflux family 2OG-FeII_Oxy_2 PF13532.6 CBY14094.1 - 9.9e-20 71.6 0.0 1.6e-19 70.9 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4543 PF15076.6 CBY14094.1 - 0.052 13.7 0.1 0.099 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) DUF1864 PF08933.11 CBY14096.1 - 0.13 10.9 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Aldedh PF00171.22 CBY14098.1 - 2.2e-101 339.7 0.6 3.7e-70 236.7 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 CBY14098.1 - 0.0076 15.7 0.0 0.057 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Ammonium_transp PF00909.21 CBY14099.1 - 0.048 12.4 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family TP_methylase PF00590.20 CBY14100.1 - 5.2e-24 85.4 0.0 1.4e-23 84.0 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Q_salvage PF10343.9 CBY14100.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family SpoVAD PF07451.11 CBY14100.1 - 0.043 12.5 0.0 0.094 11.4 0.0 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Oxidored_molyb PF00174.19 CBY14101.1 - 2.9e-52 176.7 0.0 4.6e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CBY14101.1 - 2.8e-31 108.4 0.0 5.9e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 CBY14101.1 - 8.1e-20 70.8 0.1 1.4e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 CBY14101.1 - 0.11 12.5 0.5 0.53 10.5 0.5 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat mit_SMPDase PF14724.6 CBY14102.1 - 5.1e-41 140.5 2.5 9.5e-23 80.1 0.0 4.0 2 1 2 4 4 4 4 Mitochondrial-associated sphingomyelin phosphodiesterase Tektin PF03148.14 CBY14103.1 - 7.9e-21 74.2 25.2 2.6e-20 72.5 25.2 1.7 1 1 0 1 1 1 1 Tektin family Dynactin_p22 PF07426.11 CBY14103.1 - 0.043 13.7 3.0 0.13 12.1 0.2 2.8 3 0 0 3 3 3 0 Dynactin subunit p22 DASH_Dad2 PF08654.10 CBY14103.1 - 0.11 12.9 2.5 0.14 12.6 0.2 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad2 DUF4192 PF13830.6 CBY14103.1 - 4.2 7.3 9.7 0.11 12.5 1.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) YabA PF06156.13 CBY14103.1 - 4.9 7.8 12.6 1.2 9.8 0.2 3.6 4 1 0 4 4 4 0 Initiation control protein YabA WD40 PF00400.32 CBY14104.1 - 6.9e-21 74.2 20.2 0.0085 16.9 0.0 9.6 9 0 0 9 9 9 6 WD domain, G-beta repeat HELP PF03451.14 CBY14104.1 - 9.2e-17 60.7 0.0 2.4e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 CBY14104.1 - 4.8e-10 39.6 0.1 0.00017 21.8 0.0 6.2 4 1 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 CBY14104.1 - 0.0038 16.9 0.1 0.012 15.2 0.1 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Ge1_WD40 PF16529.5 CBY14104.1 - 0.012 14.6 0.0 0.24 10.3 0.0 2.5 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4596 PF15363.6 CBY14104.1 - 0.03 14.5 0.1 5.8 7.2 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Reg_prop PF07494.11 CBY14104.1 - 0.23 11.8 1.4 24 5.6 0.1 4.0 3 0 0 3 3 3 0 Two component regulator propeller AAA_18 PF13238.6 CBY14105.1 - 0.026 15.0 0.7 0.037 14.6 0.7 1.3 1 0 0 1 1 1 0 AAA domain IF-2B PF01008.17 CBY14105.1 - 0.17 11.1 3.7 0.2 10.8 3.7 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family bZIP_1 PF00170.21 CBY14105.1 - 0.27 11.3 7.9 0.12 12.5 5.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor VWA PF00092.28 CBY14106.1 - 3.8e-39 134.7 0.0 6.7e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY14106.1 - 2.6e-16 60.2 0.0 7.8e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY14106.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec23_trunk PF04811.15 CBY14106.1 - 0.051 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Tetraspanin PF00335.20 CBY14107.1 - 0.021 14.5 8.3 0.03 14.0 8.3 1.3 1 1 0 1 1 1 0 Tetraspanin family Vma12 PF11712.8 CBY14107.1 - 9.6 6.3 7.6 2.3 8.3 4.3 1.7 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ank_2 PF12796.7 CBY14108.1 - 1.2e-10 41.8 0.1 3.4e-10 40.4 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY14108.1 - 1.6e-09 37.8 1.1 9.7e-09 35.3 0.8 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RNase_T PF00929.24 CBY14108.1 - 1.7e-09 38.4 0.0 2.7e-08 34.5 0.0 2.6 1 1 0 1 1 1 1 Exonuclease Ank PF00023.30 CBY14108.1 - 6.1e-09 35.9 0.1 0.0031 17.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CBY14108.1 - 2.5e-08 34.3 0.1 1.5e-07 31.9 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY14108.1 - 3.5e-06 26.9 0.3 0.0012 19.1 0.1 3.2 2 1 0 2 2 2 1 Ankyrin repeat TUDOR PF00567.24 CBY14109.1 - 1.1e-18 67.4 0.2 4.4e-09 36.4 0.0 4.0 4 0 0 4 4 4 3 Tudor domain SCAB-Ig PF16709.5 CBY14109.1 - 0.18 11.9 0.0 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 Ig domain of plant-specific actin-binding protein CHGN PF05679.16 CBY14110.1 - 1.1e-59 202.6 6.6 4.4e-40 138.0 0.9 2.9 1 1 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY14110.1 - 1.3e-08 34.4 0.7 2.7e-08 33.3 0.7 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Cnn_1N PF07989.11 CBY14111.1 - 8.2e-13 48.3 6.7 8.2e-13 48.3 6.7 6.8 4 3 3 7 7 7 3 Centrosomin N-terminal motif 1 Golgin_A5 PF09787.9 CBY14111.1 - 1.4 8.3 43.1 0.0082 15.6 22.5 3.9 4 0 0 4 4 4 0 Golgin subfamily A member 5 DUF812 PF05667.11 CBY14111.1 - 2.4 7.0 40.6 0.21 10.4 27.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF812) ATG16 PF08614.11 CBY14111.1 - 6 7.0 58.0 0.87 9.8 31.3 4.9 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 CBY14111.1 - 7.5 6.9 38.4 7.7 6.9 0.0 6.2 4 2 2 6 6 6 0 Plant protein of unknown function (DUF641) HeLo PF14479.6 CBY14111.1 - 9.2 6.0 22.4 0.41 10.4 0.2 3.2 3 1 0 3 3 3 0 Prion-inhibition and propagation EGF_CA PF07645.15 CBY14115.1 - 3.4e-85 280.0 358.6 1.8e-10 40.8 12.5 24.5 25 2 1 26 26 26 14 Calcium-binding EGF domain cEGF PF12662.7 CBY14115.1 - 8.3e-33 111.9 218.0 1.8e-06 27.8 2.8 24.7 25 0 0 25 25 25 14 Complement Clr-like EGF-like TIL PF01826.17 CBY14115.1 - 8.2e-23 80.4 316.6 5.7e-06 26.5 16.6 22.7 16 7 6 22 22 22 12 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 CBY14115.1 - 1.4e-20 73.1 254.8 2e-05 24.7 6.9 21.9 22 2 0 22 22 22 14 EGF domain hEGF PF12661.7 CBY14115.1 - 4.4e-08 33.5 245.9 0.04 14.6 1.1 25.3 25 1 1 26 26 26 13 Human growth factor-like EGF EGF PF00008.27 CBY14115.1 - 7.9e-08 32.5 245.2 0.074 13.4 6.8 24.5 24 0 0 24 24 24 13 EGF-like domain EGF_MSP1_1 PF12946.7 CBY14115.1 - 8.4e-05 22.5 17.7 0.00012 22.0 6.1 21.4 21 1 1 22 22 22 9 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY14115.1 - 0.00096 19.4 19.6 0.0035 17.6 3.1 22.6 21 3 2 23 23 23 12 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY14115.1 - 0.0039 17.5 1.5 0.0039 17.5 1.5 20.4 22 1 0 22 22 22 9 Pvs28 EGF domain Cadherin_3 PF16184.5 CBY14116.1 - 2.2e-87 288.5 21.6 4.1e-28 97.6 0.0 9.6 9 0 0 9 9 9 8 Cadherin-like ASFV_J13L PF05568.11 CBY14116.1 - 0.0067 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein TMEM154 PF15102.6 CBY14116.1 - 0.036 14.0 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family ASH PF15780.5 CBY14117.1 - 1.3e-10 41.4 8.9 0.013 15.7 0.0 5.6 5 0 0 5 5 5 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CH PF00307.31 CBY14117.1 - 9.2e-08 32.2 0.1 3.4e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain Motile_Sperm PF00635.26 CBY14117.1 - 7.3e-07 29.0 2.6 0.9 9.4 0.0 6.0 5 2 1 6 6 6 3 MSP (Major sperm protein) domain CAMSAP_CH PF11971.8 CBY14117.1 - 0.0061 16.4 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 CAMSAP CH domain TMEM131_like PF12371.8 CBY14118.1 - 0.066 13.5 0.5 0.29 11.4 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 131-like Motile_Sperm PF00635.26 CBY14121.1 - 3.9e-07 29.9 5.5 6.6e-06 25.9 0.0 3.7 4 0 0 4 4 4 1 MSP (Major sperm protein) domain CH PF00307.31 CBY14121.1 - 2.2e-06 27.8 0.1 4.3e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain ASH PF15780.5 CBY14121.1 - 5e-06 26.6 1.0 1.1 9.5 0.1 4.4 4 0 0 4 4 4 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CBY14121.1 - 0.0039 17.4 3.3 2.9 8.2 0.0 3.8 4 0 0 4 4 4 2 Transmembrane protein 131-like CAMSAP_CH PF11971.8 CBY14121.1 - 0.0053 16.6 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 CAMSAP CH domain DUF4368 PF14287.6 CBY14121.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) CH_2 PF06294.11 CBY14121.1 - 0.15 12.2 0.0 0.45 10.7 0.0 1.9 1 0 0 1 1 1 0 CH-like domain in sperm protein TMEM131_like PF12371.8 CBY14122.1 - 0.066 13.5 0.5 0.29 11.4 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 131-like Gal-3-0_sulfotr PF06990.11 CBY14125.1 - 4.9e-54 183.8 0.3 6e-54 183.5 0.3 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_3 PF13469.6 CBY14125.1 - 0.003 18.0 0.0 0.0054 17.1 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family PatG_C PF18065.1 CBY14127.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 PatG C-terminal DUF3671 PF12420.8 CBY14127.1 - 0.18 11.9 2.3 2 8.5 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF981 PF06168.11 CBY14127.1 - 0.99 9.3 6.6 1.3 8.9 0.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF981) Lectin_C PF00059.21 CBY14128.1 - 0.0044 17.7 0.9 0.02 15.6 0.9 1.9 1 1 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 CBY14129.1 - 0.014 16.2 0.0 0.015 16.0 0.0 1.2 1 0 0 1 1 1 0 Lectin C-type domain COesterase PF00135.28 CBY14130.1 - 2.1e-60 205.0 0.0 6.7e-54 183.6 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY14130.1 - 0.0019 18.1 0.0 0.0066 16.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold IFR3_antag PF14754.6 CBY14130.1 - 0.034 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Papain-like auto-proteinase XFP_N PF09364.10 CBY14132.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain CotH PF08757.11 CBY14137.1 - 1.4e-45 156.2 0.0 1.2e-44 153.2 0.0 2.0 1 1 0 1 1 1 1 CotH kinase protein Fn3_assoc PF13287.6 CBY14137.1 - 5.1e-13 49.0 0.0 8.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Fn3 associated LTD PF00932.19 CBY14137.1 - 5.9e-13 49.1 0.0 1.6e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Lamin Tail Domain CHB_HEX_C_1 PF13290.6 CBY14137.1 - 7.5e-13 48.3 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF2760 PF10816.8 CBY14138.1 - 6.5e-47 158.4 0.0 8.1e-47 158.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2760) HSP70 PF00012.20 CBY14139.1 - 3.8e-17 61.7 0.0 5.3e-14 51.3 0.0 3.3 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBY14139.1 - 3e-06 26.3 0.0 1.3e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein MutL PF13941.6 CBY14139.1 - 0.054 12.1 0.1 0.36 9.4 0.0 2.1 2 0 0 2 2 2 0 MutL protein ROK PF00480.20 CBY14139.1 - 0.084 12.3 0.0 0.87 9.0 0.0 2.1 2 0 0 2 2 2 0 ROK family FtsA PF14450.6 CBY14139.1 - 0.16 12.4 0.0 0.92 10.0 0.0 2.1 2 0 0 2 2 2 0 Cell division protein FtsA DUF3731 PF12531.8 CBY14140.1 - 1.7e-41 142.7 0.2 2.7e-41 142.0 0.2 1.3 1 0 0 1 1 1 1 DNA-K related protein RuvA_N PF01330.21 CBY14141.1 - 4.1e-21 74.8 0.1 1.1e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 RuvA N terminal domain HHH_5 PF14520.6 CBY14141.1 - 6.7e-15 55.4 0.3 1.1e-13 51.6 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain RuvA_C PF07499.13 CBY14141.1 - 2.9e-11 43.6 0.9 2.9e-11 43.6 0.9 1.7 2 0 0 2 2 2 1 RuvA, C-terminal domain HHH PF00633.23 CBY14141.1 - 6.4e-05 22.6 2.2 0.0041 16.9 0.1 3.9 5 0 0 5 5 5 1 Helix-hairpin-helix motif Transposase_20 PF02371.16 CBY14141.1 - 0.003 17.8 2.0 0.95 9.8 0.0 3.1 4 0 0 4 4 4 2 Transposase IS116/IS110/IS902 family DNA_pol_lambd_f PF10391.9 CBY14141.1 - 0.0092 15.8 2.0 0.67 9.8 0.0 3.5 4 0 0 4 4 4 1 Fingers domain of DNA polymerase lambda HHH_3 PF12836.7 CBY14141.1 - 0.016 15.4 0.3 0.35 11.2 0.0 3.0 4 0 0 4 4 4 0 Helix-hairpin-helix motif HHH_8 PF14716.6 CBY14141.1 - 0.018 15.4 0.3 1.6 9.1 0.1 3.1 2 1 1 3 3 3 0 Helix-hairpin-helix domain HHH_2 PF12826.7 CBY14141.1 - 0.025 14.7 0.2 3 8.0 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 CBY14141.1 - 0.039 14.3 1.4 8.1 7.0 0.0 3.5 4 0 0 4 4 4 0 IMS family HHH motif CinA PF02464.17 CBY14141.1 - 0.087 12.4 1.6 0.11 12.0 1.6 1.1 1 0 0 1 1 1 0 Competence-damaged protein Alpha_L_fucos PF01120.17 CBY14144.1 - 4.9e-83 279.5 0.0 6.6e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 CBY14144.1 - 5.7e-13 49.1 0.0 9.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain GHL6 PF14871.6 CBY14144.1 - 0.0011 19.2 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 Fucosidase_C PF16757.5 CBY14144.1 - 0.15 12.6 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Alpha-L-fucosidase C-terminal domain PEP-CTERM PF07589.11 CBY14145.1 - 0.012 15.6 1.9 0.056 13.5 1.9 2.3 1 0 0 1 1 1 0 PEP-CTERM motif Dockerin_1 PF00404.18 CBY14145.1 - 0.04 14.1 1.1 0.079 13.2 1.1 1.5 1 0 0 1 1 1 0 Dockerin type I domain CSD PF00313.22 CBY14146.1 - 9.4e-10 38.2 0.2 1.5e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain S1-like PF14444.6 CBY14146.1 - 0.0023 17.8 0.1 0.0052 16.7 0.1 1.7 1 0 0 1 1 1 1 S1-like Helicase_C PF00271.31 CBY14147.1 - 1.3e-18 67.4 0.6 5.1e-18 65.4 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CBY14147.1 - 3.5e-11 42.8 0.2 9.2e-11 41.4 0.2 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SNF2_N PF00176.23 CBY14147.1 - 2.6e-09 36.3 0.1 4.7e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 CBY14147.1 - 0.018 14.3 0.4 0.24 10.6 0.1 2.3 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase CRISPR_Cas9_WED PF18061.1 CBY14147.1 - 0.021 14.9 0.9 0.098 12.7 0.7 2.2 2 1 0 2 2 2 0 CRISPR-Cas9 WED domain AhpC-TSA PF00578.21 CBY14148.1 - 0.039 13.9 0.0 0.07 13.0 0.0 1.6 2 0 0 2 2 2 0 AhpC/TSA family A_thal_3526 PF09713.10 CBY14149.1 - 0.062 13.6 0.7 0.11 12.8 0.7 1.4 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) EF-hand_1 PF00036.32 CBY14150.1 - 5.4e-07 28.7 0.1 0.11 12.0 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY14150.1 - 2.7e-05 23.8 0.1 0.16 11.9 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY14150.1 - 0.00085 18.7 1.0 0.065 12.8 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBY14150.1 - 0.0025 18.2 0.2 0.34 11.4 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY14150.1 - 0.038 13.8 1.0 13 5.8 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair PMP22_Claudin PF00822.20 CBY14152.1 - 2.4e-10 40.5 7.5 3.4e-10 40.1 7.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF4401 PF14351.6 CBY14152.1 - 0.00014 21.3 1.6 0.00089 18.7 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4401) Claudin_2 PF13903.6 CBY14152.1 - 0.00025 20.8 8.4 0.00057 19.7 8.4 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_5 PF13346.6 CBY14152.1 - 0.4 10.2 3.4 5.9 6.4 0.3 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein YccF PF03733.13 CBY14152.1 - 0.51 11.1 0.0 0.51 11.1 0.0 3.2 4 0 0 4 4 4 0 Inner membrane component domain Pox_A14 PF05767.12 CBY14152.1 - 8.7 6.6 7.9 10 6.3 0.6 3.2 2 1 2 4 4 4 0 Poxvirus virion envelope protein A14 DUF2723 PF11028.8 CBY14153.1 - 1.3e-21 77.3 5.4 1.3e-21 77.3 5.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) DUF2093 PF09866.9 CBY14153.1 - 0.13 11.8 0.3 0.26 10.8 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) TEX15 PF15326.6 CBY14157.1 - 0.85 9.3 0.0 0.85 9.3 0.0 2.4 2 1 1 3 3 3 0 Testis expressed sequence 15 SET PF00856.28 CBY14158.1 - 1e-12 48.8 0.1 2e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 SET domain Trypsin PF00089.26 CBY14159.1 - 1.1e-48 166.0 0.1 1.8e-48 165.3 0.1 1.3 1 0 0 1 1 1 1 Trypsin Tctex-1 PF03645.13 CBY14160.1 - 6.8e-11 42.3 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Tctex-1 family Bromo_TP PF07524.13 CBY14160.1 - 0.16 12.0 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Lipase PF00151.19 CBY14163.1 - 1.6e-22 80.3 0.0 2.2e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.25 CBY14163.1 - 0.0073 16.2 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Sigma_reg_N PF13800.6 CBY14163.1 - 0.026 14.8 1.4 0.047 14.0 1.4 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal AtpR PF12966.7 CBY14163.1 - 0.034 14.6 0.4 0.07 13.6 0.4 1.4 1 0 0 1 1 1 0 N-ATPase, AtpR subunit EGF_CA PF07645.15 CBY14164.1 - 7.8e-179 579.7 560.7 2.3e-09 37.3 10.4 34.3 32 2 2 34 34 34 29 Calcium-binding EGF domain cEGF PF12662.7 CBY14164.1 - 1.6e-91 299.7 326.3 5.5e-10 39.0 3.0 32.8 32 0 0 32 32 32 27 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY14164.1 - 7e-84 275.7 424.0 1.8e-08 34.4 9.2 33.1 27 4 4 31 31 30 26 EGF domain EGF PF00008.27 CBY14164.1 - 1.3e-45 153.3 395.4 7.4e-05 23.0 9.6 34.2 32 2 1 33 33 33 23 EGF-like domain FXa_inhibition PF14670.6 CBY14164.1 - 1.9e-36 124.0 416.1 7.4e-09 35.7 6.8 32.2 22 8 9 31 31 30 24 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY14164.1 - 1.3e-20 73.1 415.0 3.9e-05 23.6 7.4 32.2 31 0 0 31 31 31 20 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY14164.1 - 2.7e-19 69.2 404.9 0.011 16.0 5.9 31.9 30 1 1 31 31 31 21 Pvs28 EGF domain hEGF PF12661.7 CBY14164.1 - 2.8e-18 65.8 339.6 0.0037 17.8 2.7 34.5 34 0 0 34 34 33 20 Human growth factor-like EGF Sushi PF00084.20 CBY14164.1 - 9.5e-18 64.6 7.2 9.5e-07 29.3 0.1 13.4 17 0 0 17 17 13 4 Sushi repeat (SCR repeat) Ig_3 PF13927.6 CBY14164.1 - 8.8e-09 35.9 1.6 8.2e-08 32.7 0.0 3.6 3 0 0 3 3 2 1 Immunoglobulin domain I-set PF07679.16 CBY14164.1 - 1.1e-08 35.0 0.0 6.9e-08 32.5 0.0 2.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 CBY14164.1 - 1.1e-07 31.9 0.2 7.1e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 CBY14164.1 - 4.7e-06 26.7 0.3 0.00016 21.8 0.0 3.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 CBY14164.1 - 0.003 17.8 0.0 0.003 17.8 0.0 3.8 3 0 0 3 3 3 1 Immunoglobulin domain Glyco_hydro_31 PF01055.26 CBY14165.1 - 6.1e-35 121.3 3.2 1.1e-34 120.5 3.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4533 PF15047.6 CBY14166.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) TPR_2 PF07719.17 CBY14167.1 - 2.5e-05 24.1 1.3 0.088 13.0 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY14167.1 - 0.00079 19.1 3.6 0.036 13.9 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY14167.1 - 0.0037 17.4 3.3 1.9 8.9 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 CBY14167.1 - 0.0037 17.2 1.8 0.96 9.5 0.3 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY14167.1 - 0.0043 17.7 0.1 19 6.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY14167.1 - 0.0099 15.5 2.6 0.61 9.8 0.2 3.2 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 CBY14167.1 - 0.01 15.8 0.6 2.3 8.4 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY14167.1 - 0.025 14.9 0.2 5.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY14167.1 - 0.034 14.4 2.0 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY14167.1 - 0.061 13.5 0.3 12 6.2 0.1 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FMO-like PF00743.19 CBY14169.1 - 1.7e-24 86.2 1.2 1.2e-22 80.1 1.2 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CBY14169.1 - 1.3e-13 50.9 0.0 9.6e-11 41.5 0.0 2.9 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CBY14169.1 - 5.6e-12 45.5 0.0 4.6e-09 35.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CBY14169.1 - 1.4e-08 34.9 0.0 3.3e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBY14169.1 - 1.8e-07 30.7 0.0 0.00019 20.7 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBY14169.1 - 0.00017 21.3 0.0 0.024 14.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CBY14169.1 - 0.00024 21.2 0.0 0.46 10.6 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 CBY14169.1 - 0.0012 18.8 0.0 0.66 9.9 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 CBY14169.1 - 0.004 16.4 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CBY14169.1 - 0.0097 16.4 0.1 0.081 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CBY14169.1 - 0.048 14.1 0.1 0.83 10.1 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 CBY14169.1 - 0.096 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 CBY14169.1 - 0.11 11.9 0.1 0.96 8.8 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBY14169.1 - 0.16 11.5 0.2 4.8 6.7 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Metallophos PF00149.28 CBY14171.1 - 2e-40 139.5 0.1 2.7e-40 139.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBY14171.1 - 0.00029 21.2 0.2 0.00084 19.7 0.2 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 CBY14171.1 - 0.056 13.6 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 CBY14172.1 - 1.4e-12 47.3 0.1 4.7e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 CBY14172.1 - 0.00074 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 CBY14172.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Diphthamide_syn PF01866.17 CBY14173.1 - 1.1e-41 143.3 0.0 1.3e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DKCLD PF08068.12 CBY14174.1 - 9.9e-30 102.4 0.2 2.4e-29 101.2 0.2 1.7 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.18 CBY14174.1 - 6.3e-25 88.3 0.4 4.4e-22 79.1 0.4 3.6 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CBY14174.1 - 7.5e-19 67.6 0.7 1.8e-18 66.5 0.7 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CBY14174.1 - 1.1e-18 66.9 1.7 3.2e-18 65.5 1.7 1.8 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 CBY14174.1 - 0.016 15.4 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 UPF0113 PUA domain RNA_polI_A34 PF08208.11 CBY14174.1 - 0.59 10.2 28.4 1.1 9.3 28.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 CBY14174.1 - 4.9 6.9 14.0 6.5 6.5 14.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C3HC4_2 PF13923.6 CBY14175.1 - 5.3e-08 32.6 9.9 8.9e-08 31.9 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY14175.1 - 6.4e-07 29.1 9.7 1.1e-06 28.4 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY14175.1 - 1e-05 25.5 9.1 2.2e-05 24.4 9.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CBY14175.1 - 2.1e-05 24.6 11.4 4.1e-05 23.6 10.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBY14175.1 - 0.00015 22.1 9.5 0.00027 21.2 9.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 CBY14175.1 - 0.00041 20.2 4.8 0.00077 19.3 4.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CBY14175.1 - 0.0005 20.0 9.4 0.0011 18.8 9.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY14175.1 - 0.0031 17.3 6.9 0.0053 16.6 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY14175.1 - 0.016 15.4 8.0 0.024 14.7 8.0 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 CBY14175.1 - 0.019 15.3 5.2 0.019 15.3 5.2 1.7 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 CBY14175.1 - 0.045 13.6 4.1 0.082 12.7 4.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 CBY14175.1 - 0.05 13.5 4.9 0.11 12.5 4.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 CBY14175.1 - 0.22 11.5 6.0 0.55 10.3 6.0 1.7 1 1 0 1 1 1 0 zinc-ribbons Prok-RING_4 PF14447.6 CBY14175.1 - 0.29 11.0 8.5 0.66 9.9 8.5 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.11 CBY14175.1 - 0.81 9.8 8.1 2.5 8.3 8.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) SNARE_assoc PF09335.11 CBY14176.1 - 2.6e-08 34.4 0.0 2.6e-08 34.4 0.0 3.0 3 1 0 3 3 3 1 SNARE associated Golgi protein Sec7 PF01369.20 CBY14177.1 - 1.4e-60 204.1 0.0 2e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 CBY14177.1 - 1.8e-23 83.0 0.0 3.8e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CBY14177.1 - 1e-05 25.9 0.0 3e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CBY14177.1 - 0.0018 18.5 0.0 0.013 15.8 0.0 2.2 1 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 CBY14177.1 - 0.0034 17.5 0.1 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 CBY14177.1 - 0.058 13.7 0.0 18 5.6 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Ribosomal_L19 PF01245.20 CBY14178.1 - 2e-13 50.2 0.0 4.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 RRM_1 PF00076.22 CBY14179.1 - 5.5e-36 122.2 2.3 1.1e-13 50.8 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 CBY14179.1 - 3.1e-30 103.9 0.2 7.4e-30 102.7 0.2 1.7 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 CBY14179.1 - 1.6e-06 28.1 0.0 0.18 11.9 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 CBY14179.1 - 1.1e-05 25.1 0.1 2.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CBY14179.1 - 0.027 14.5 0.0 0.29 11.2 0.0 2.6 3 0 0 3 3 3 0 RNA binding domain Spo7_2_N PF15407.6 CBY14179.1 - 0.046 13.4 0.0 12 5.6 0.0 2.9 2 0 0 2 2 2 0 Sporulation protein family 7 DUF1707 PF08044.11 CBY14179.1 - 0.056 13.5 0.2 0.5 10.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) RRM_occluded PF16842.5 CBY14179.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF1866 PF08952.11 CBY14179.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Aa_trans PF01490.18 CBY14180.1 - 9.5e-12 44.3 35.0 6.3e-08 31.7 24.1 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF4231 PF14015.6 CBY14180.1 - 5.2 7.6 16.1 1.3 9.6 0.2 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) BBS2_N PF14781.6 CBY14181.1 - 0.039 13.8 0.0 5.5 7.0 0.0 3.2 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.32 CBY14181.1 - 0.18 12.7 4.8 16 6.6 0.0 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat CNOT11 PF10155.9 CBY14182.1 - 0.13 12.4 0.4 3.4 7.8 0.1 2.9 2 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 JmjC PF02373.22 CBY14183.1 - 1.9e-14 54.0 1.7 5.1e-11 43.0 1.7 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CBY14183.1 - 6.2e-14 52.3 1.9 5.2e-06 26.4 0.2 2.2 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 CBY14183.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Glyco_transf_5 PF08323.11 CBY14183.1 - 0.08 12.6 0.2 0.22 11.2 0.0 1.7 1 1 1 2 2 2 0 Starch synthase catalytic domain UBA_4 PF14555.6 CBY14184.1 - 0.008 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain GIT1_C PF12205.8 CBY14185.1 - 0.26 11.4 8.1 0.81 9.8 8.1 1.9 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Latarcin PF10279.9 CBY14185.1 - 0.58 10.6 2.5 0.88 10.0 0.9 2.1 2 0 0 2 2 2 0 Latarcin precursor DUF883 PF05957.13 CBY14185.1 - 0.71 10.5 2.8 2 9.1 2.8 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YkyA PF10368.9 CBY14185.1 - 9.9 5.8 17.7 0.076 12.7 8.3 2.2 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein Kelch_2 PF07646.15 CBY14186.1 - 0.023 14.7 0.4 0.37 10.8 0.0 3.0 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 CBY14186.1 - 0.14 12.2 0.0 32 4.6 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY14189.1 - 5.7e-06 26.1 1.0 1.3 9.1 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 CBY14189.1 - 0.00093 19.1 4.0 0.029 14.4 0.0 3.6 3 0 0 3 3 3 1 Kelch motif DUF868 PF05910.12 CBY14189.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) Kelch_6 PF13964.6 CBY14189.1 - 0.29 11.5 2.4 8.1 6.9 0.0 3.6 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 CBY14189.1 - 0.61 10.1 6.0 0.48 10.5 0.3 3.4 3 1 1 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY14190.1 - 0.0039 17.1 0.9 1.9 8.6 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY14190.1 - 0.0064 16.7 2.2 0.3 11.5 0.0 3.7 4 0 0 4 4 4 1 Kelch motif LLC1 PF14945.6 CBY14191.1 - 7.6e-31 107.2 0.6 1.2e-30 106.5 0.6 1.3 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Phage_term_sma PF07141.11 CBY14191.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit SIX1_SD PF16878.5 CBY14192.1 - 1.8e-42 144.3 6.1 6.1e-42 142.6 1.6 2.6 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CBY14192.1 - 2.9e-14 52.6 2.0 2.9e-14 52.6 2.0 2.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY14192.1 - 8e-09 35.3 0.4 2e-08 34.0 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF4813 PF16072.5 CBY14192.1 - 0.57 9.8 10.6 1.1 8.9 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Astacin PF01400.24 CBY14195.1 - 7.8e-35 120.2 0.0 9.4e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CBY14195.1 - 2.2e-05 24.2 0.1 2.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CBY14195.1 - 0.0012 19.4 0.5 0.0018 18.8 0.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CBY14195.1 - 0.013 15.4 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 CBY14195.1 - 0.025 14.7 0.2 0.034 14.3 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 CBY14195.1 - 0.037 13.3 0.4 0.054 12.7 0.4 1.2 1 0 0 1 1 1 0 Met-zincin DUF3152 PF11350.8 CBY14195.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin_2 PF13574.6 CBY14195.1 - 0.082 12.8 0.1 0.085 12.7 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M8 PF01457.16 CBY14195.1 - 0.14 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin PTR2 PF00854.21 CBY14196.1 - 3.4e-71 240.2 17.8 1.6e-30 106.3 1.4 3.1 2 1 1 3 3 3 3 POT family TMEM52 PF14979.6 CBY14197.1 - 1.2 9.1 7.4 1.6 8.7 7.4 1.2 1 0 0 1 1 1 0 Transmembrane 52 GAS PF13851.6 CBY14198.1 - 3e-06 26.8 12.8 3e-06 26.8 12.8 7.3 2 2 5 7 7 7 2 Growth-arrest specific micro-tubule binding HALZ PF02183.18 CBY14198.1 - 0.0076 16.5 0.3 0.0076 16.5 0.3 8.4 7 4 2 9 9 9 2 Homeobox associated leucine zipper APC_N_CC PF16689.5 CBY14198.1 - 0.68 10.0 20.2 0.13 12.3 1.4 6.0 5 0 0 5 5 5 0 Coiled-coil N-terminus of APC, dimerisation domain Pox_A_type_inc PF04508.12 CBY14198.1 - 0.92 9.5 0.0 0.92 9.5 0.0 4.6 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF3602 PF12223.8 CBY14198.1 - 1.4 9.6 6.0 0.31 11.7 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) DUF3138 PF11336.8 CBY14198.1 - 5.2 5.6 10.0 9.5 4.7 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) APS_kinase PF01583.20 CBY14199.1 - 4.5e-70 234.6 0.0 7.6e-70 233.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 CBY14199.1 - 6.1e-65 218.6 0.0 8.3e-65 218.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CBY14199.1 - 1.4e-46 158.0 0.0 2.4e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 CBY14199.1 - 4.2e-05 23.7 0.0 9.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CBY14199.1 - 0.0022 17.5 0.0 0.0055 16.2 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CBY14199.1 - 0.0046 17.5 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY14199.1 - 0.0071 16.7 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 CBY14199.1 - 0.025 13.5 0.0 0.055 12.4 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 CBY14199.1 - 0.03 14.0 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase RsgA_GTPase PF03193.16 CBY14199.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_17 PF13207.6 CBY14199.1 - 0.056 13.9 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CBY14199.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 CBY14199.1 - 0.087 12.7 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 NTPase CTP_transf_like PF01467.26 CBY14199.1 - 0.11 12.6 0.0 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Cytidylyltransferase-like SRP54 PF00448.22 CBY14199.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CBY14199.1 - 0.13 11.6 0.0 0.55 9.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 CBY14199.1 - 0.2 12.2 0.0 0.42 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter CLASP_N PF12348.8 CBY14200.1 - 5.2e-21 75.3 2.8 2.5e-08 33.8 0.0 5.5 5 1 1 6 6 6 3 CLASP N terminal Cnd1 PF12717.7 CBY14200.1 - 0.0083 16.2 0.5 0.28 11.2 0.5 3.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CBY14200.1 - 0.017 15.6 0.6 8.1 7.1 0.1 4.2 2 1 1 3 3 3 0 HEAT-like repeat SAPS PF04499.15 CBY14200.1 - 0.087 11.6 0.7 0.18 10.6 0.7 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TAN PF11640.8 CBY14200.1 - 0.18 11.9 6.2 3.5 7.8 0.1 3.8 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair TruD PF01142.18 CBY14201.1 - 1.7e-57 195.1 0.0 6.3e-57 193.3 0.0 1.7 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) zf-MYND PF01753.18 CBY14202.1 - 7.1e-06 26.0 17.6 1.4e-05 25.1 17.6 1.5 1 0 0 1 1 1 1 MYND finger PLC-beta_C PF08703.10 CBY14202.1 - 1.8e-05 24.8 9.1 2.5e-05 24.4 9.1 1.2 1 0 0 1 1 1 1 PLC-beta C terminal DUF1492 PF07374.11 CBY14202.1 - 0.027 14.6 4.8 0.037 14.2 4.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) Phage_GPO PF05929.11 CBY14202.1 - 0.13 11.9 4.8 0.15 11.6 4.8 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF883 PF05957.13 CBY14202.1 - 0.15 12.6 3.6 0.23 12.1 3.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RRP36 PF06102.12 CBY14202.1 - 0.23 11.4 8.6 0.34 10.9 8.6 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 ParB PF08775.10 CBY14202.1 - 0.26 11.7 7.8 0.48 10.9 7.8 1.4 1 1 0 1 1 1 0 ParB family RNase_J_C PF17770.1 CBY14202.1 - 0.43 11.7 6.1 0.16 13.0 2.4 2.0 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain LMBR1 PF04791.16 CBY14202.1 - 0.8 8.5 2.3 0.84 8.5 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CD225 PF04505.12 CBY14204.1 - 6.8e-06 26.1 1.7 0.00018 21.6 0.1 2.2 2 0 0 2 2 2 2 Interferon-induced transmembrane protein DUF2062 PF09835.9 CBY14204.1 - 0.0085 16.0 1.8 0.012 15.5 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF4190 PF13828.6 CBY14204.1 - 0.022 14.5 2.7 3.3 7.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) FAM176 PF14851.6 CBY14207.1 - 0.00035 20.3 0.0 0.00035 20.3 0.0 2.3 2 1 0 2 2 2 1 FAM176 family EphA2_TM PF14575.6 CBY14207.1 - 0.0055 17.6 0.0 0.016 16.1 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.11 CBY14207.1 - 0.025 15.0 2.6 0.025 15.0 2.6 4.0 1 1 3 4 4 4 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4064 PF13273.6 CBY14207.1 - 0.027 14.7 0.1 0.057 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Pilin_N PF07790.11 CBY14207.1 - 0.032 15.1 0.0 0.032 15.1 0.0 2.7 3 1 0 3 3 3 0 Archaeal Type IV pilin, N-terminal Peptidase_M56 PF05569.11 CBY14207.1 - 0.087 12.0 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 Nramp PF01566.18 CBY14207.1 - 0.15 11.0 0.5 0.25 10.2 0.1 1.5 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein Insulin_TMD PF17870.1 CBY14207.1 - 0.17 12.0 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4834 PF16118.5 CBY14207.1 - 0.26 12.3 0.0 0.26 12.3 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4834) RIFIN PF02009.16 CBY14207.1 - 1 9.2 10.1 0.59 10.0 6.9 1.9 1 1 1 2 2 2 0 Rifin TMEM154 PF15102.6 CBY14207.1 - 5.2 7.0 34.4 8.1 6.4 24.0 3.7 1 1 2 3 3 3 0 TMEM154 protein family Neur_chan_LBD PF02931.23 CBY14209.1 - 1.9e-56 190.9 0.5 2.9e-56 190.3 0.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY14209.1 - 1.2e-35 123.7 5.9 1.6e-27 97.1 4.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Trefoil PF00088.18 CBY14212.1 - 3.4e-21 74.8 25.9 2e-10 40.3 5.4 3.5 3 0 0 3 3 3 3 Trefoil (P-type) domain Xan_ur_permease PF00860.20 CBY14213.1 - 2e-86 290.1 20.3 3.2e-86 289.5 20.3 1.2 1 0 0 1 1 1 1 Permease family EGF_3 PF12947.7 CBY14214.1 - 3.9e-09 36.5 5.9 5.7e-09 36.0 5.9 1.3 1 0 0 1 1 1 1 EGF domain hEGF PF12661.7 CBY14214.1 - 6e-06 26.7 1.9 1.3e-05 25.7 1.9 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF EGF PF00008.27 CBY14214.1 - 8e-05 22.9 4.1 0.00013 22.2 4.1 1.4 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.15 CBY14214.1 - 0.00012 22.1 6.9 0.00024 21.3 6.9 1.3 1 0 0 1 1 1 1 Calcium-binding EGF domain cEGF PF12662.7 CBY14214.1 - 0.0064 16.4 2.1 0.0064 16.4 2.1 1.9 2 0 0 2 2 2 1 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CBY14214.1 - 0.017 15.5 1.8 0.03 14.6 1.8 1.4 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_2 PF07974.13 CBY14214.1 - 0.35 11.3 5.0 0.71 10.3 5.0 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_MSP1_1 PF12946.7 CBY14214.1 - 0.4 10.8 4.9 0.72 10.0 4.9 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY14214.1 - 1.6 9.1 6.7 2.6 8.4 6.7 1.3 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site MEA1 PF06910.11 CBY14215.1 - 5.1e-11 43.3 3.9 1.2e-10 42.1 3.9 1.6 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) PMSI1 PF15322.6 CBY14215.1 - 0.069 12.6 1.5 0.071 12.6 1.5 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative zf-C2H2 PF00096.26 CBY14216.1 - 8.5e-07 29.1 13.9 0.017 15.6 0.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY14216.1 - 0.00022 21.8 11.6 0.35 11.8 0.1 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CBY14216.1 - 0.028 14.7 8.3 1.8 8.9 4.6 3.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 CBY14216.1 - 0.051 13.2 7.6 0.1 12.2 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-P11 PF03854.14 CBY14216.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.3 3 0 0 3 3 3 0 P-11 zinc finger zf_C2H2_ZHX PF18387.1 CBY14216.1 - 0.42 10.3 3.9 1.2 8.8 0.2 2.6 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 CBY14216.1 - 0.67 10.4 5.5 31 5.2 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 CBY14216.1 - 2.3 8.1 6.8 13 5.7 0.1 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Actin_micro PF17003.5 CBY14216.1 - 4.6 6.3 9.7 3.4 6.7 1.2 2.8 1 1 2 3 3 3 0 Putative actin-like family TetR_C_23 PF17931.1 CBY14217.1 - 0.073 13.2 3.0 0.096 12.8 0.8 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LON_substr_bdg PF02190.16 CBY14217.1 - 0.51 10.2 2.2 1.1 9.1 2.2 1.6 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Claudin_2 PF13903.6 CBY14218.1 - 7.9e-05 22.5 11.1 0.0073 16.1 12.7 2.8 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.6 CBY14218.1 - 0.0056 16.6 2.1 0.0073 16.2 0.8 1.9 1 1 1 2 2 2 1 Voltage-dependent calcium channel gamma-like subunit protein family Nitrate_red_gam PF02665.14 CBY14218.1 - 0.042 13.4 0.6 0.065 12.8 0.5 1.3 1 1 0 1 1 1 0 Nitrate reductase gamma subunit DUF4999 PF16390.5 CBY14218.1 - 0.14 12.4 0.1 7.4 6.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function Glyco_transf_8 PF01501.20 CBY14218.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 DUF2613 PF11021.8 CBY14218.1 - 2.3 8.4 0.0 2.3 8.4 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2613) PsbY PF06298.11 CBY14218.1 - 3.6 7.6 7.7 0.6 10.1 0.5 2.4 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) O-FucT PF10250.9 CBY14220.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase YBD PF17725.1 CBY14221.1 - 3.8e-31 108.6 0.4 4.7e-31 108.3 0.4 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 CBY14221.1 - 5.5e-26 90.4 0.0 1.1e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain YBD PF17725.1 CBY14222.1 - 3.7e-31 108.6 0.4 4.6e-31 108.3 0.4 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 CBY14222.1 - 5.5e-26 90.4 0.0 1.1e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain zf-RING_4 PF14570.6 CBY14223.1 - 2.2e-16 59.4 9.8 3.8e-16 58.6 9.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CBY14223.1 - 2.1e-05 24.3 8.2 3.9e-05 23.4 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CBY14223.1 - 0.00074 19.3 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.6 CBY14223.1 - 0.0084 16.2 2.0 0.024 14.8 2.0 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger Nup35_RRM_2 PF14605.6 CBY14223.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.6 CBY14223.1 - 0.12 12.2 10.8 0.24 11.3 10.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 CBY14223.1 - 0.19 11.7 8.7 0.39 10.6 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY14223.1 - 0.89 9.7 5.1 2 8.6 5.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Asparaginase_2 PF01112.18 CBY14223.1 - 6.5 5.7 5.7 0.99 8.4 0.7 1.9 2 0 0 2 2 2 0 Asparaginase Torus PF16131.5 CBY14223.1 - 9.8 6.9 8.7 0.28 11.9 0.4 2.7 2 1 0 2 2 2 0 Torus domain zf-RING_4 PF14570.6 CBY14224.1 - 2.2e-16 59.4 9.8 3.9e-16 58.6 9.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CBY14224.1 - 2.2e-05 24.2 8.2 4e-05 23.4 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CBY14224.1 - 0.00073 19.3 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.6 CBY14224.1 - 0.0073 16.4 1.9 0.02 15.0 1.9 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger Nup35_RRM_2 PF14605.6 CBY14224.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.6 CBY14224.1 - 0.12 12.2 10.8 0.25 11.2 10.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 CBY14224.1 - 0.19 11.6 8.7 0.4 10.6 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY14224.1 - 0.38 10.9 4.6 0.85 9.8 4.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Asparaginase_2 PF01112.18 CBY14224.1 - 6.3 5.7 5.9 1 8.3 0.6 2.0 2 0 0 2 2 2 0 Asparaginase MARVEL PF01284.23 CBY14225.1 - 3.9e-06 27.0 6.6 5.1e-06 26.6 6.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF373 PF04123.13 CBY14225.1 - 0.31 10.4 1.8 0.46 9.9 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF2892 PF11127.8 CBY14225.1 - 8.3 6.5 8.0 1.4 9.0 1.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) Patched PF02460.18 CBY14228.1 - 4.3e-61 207.0 28.2 3.9e-44 151.0 4.8 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CBY14228.1 - 2.4e-42 144.4 4.9 2.4e-42 144.4 4.9 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CBY14228.1 - 0.00018 20.6 8.0 0.00018 20.6 8.0 2.3 2 0 0 2 2 2 1 MMPL family MSC PF09402.10 CBY14229.1 - 0.81 9.1 5.7 0.87 9.0 5.7 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain GET2 PF08690.10 CBY14229.1 - 0.81 9.3 6.4 0.92 9.1 6.4 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 Ribosomal_L6e PF01159.19 CBY14229.1 - 0.94 10.0 6.2 1.1 9.8 6.1 1.3 1 1 0 1 1 1 0 Ribosomal protein L6e PBP_sp32 PF07222.12 CBY14229.1 - 4.2 6.8 10.3 4.8 6.6 10.3 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.14 CBY14229.1 - 6.9 6.4 12.2 14 5.5 12.2 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein 7tm_1 PF00001.21 CBY14230.1 - 1.3e-14 54.2 19.8 2.7e-14 53.1 18.8 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CBY14230.1 - 0.00095 18.9 20.6 0.00095 18.9 20.6 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Sulfotransfer_2 PF03567.14 CBY14231.1 - 2.6e-19 70.1 1.3 3.4e-19 69.7 1.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family Inos-1-P_synth PF01658.17 CBY14231.1 - 0.022 15.0 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase PheRS_DBD3 PF18553.1 CBY14231.1 - 0.16 12.3 0.0 0.7 10.2 0.0 2.1 2 0 0 2 2 2 0 PheRS DNA binding domain 3 LSM PF01423.22 CBY14233.1 - 5.9e-16 57.9 1.9 7.3e-16 57.6 1.9 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CBY14233.1 - 0.0011 18.6 0.4 0.0016 18.1 0.4 1.4 1 0 0 1 1 1 1 Hfq protein Sec10 PF07393.11 CBY14234.1 - 1.1e-07 30.7 0.1 1.4e-07 30.4 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 RINT1_TIP1 PF04437.13 CBY14234.1 - 5.1e-07 29.0 0.1 6.7e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec6 PF06046.13 CBY14234.1 - 0.00026 19.5 0.2 0.0029 16.0 0.1 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec6 GlutR_dimer PF00745.20 CBY14234.1 - 0.045 14.2 0.5 1.5 9.3 0.0 2.6 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Skp1 PF01466.19 CBY14234.1 - 0.052 13.7 0.0 0.67 10.1 0.0 2.5 2 0 0 2 2 2 0 Skp1 family, dimerisation domain TraF_2 PF13729.6 CBY14234.1 - 0.14 11.5 0.2 0.44 9.9 0.2 1.4 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein Kelch_2 PF07646.15 CBY14235.1 - 8.5e-05 22.4 1.4 0.56 10.3 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY14235.1 - 0.0024 18.1 3.7 0.66 10.4 0.1 3.6 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY14235.1 - 0.0034 17.4 2.8 1.2 9.2 0.0 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY14235.1 - 0.34 10.9 0.0 0.34 10.9 0.0 4.0 5 0 0 5 5 5 0 Kelch motif Kelch_2 PF07646.15 CBY14236.1 - 8e-06 25.6 3.2 1.7 8.7 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 CBY14236.1 - 0.0026 18.0 11.8 2.7 8.4 0.1 5.6 5 1 1 6 6 6 2 Kelch motif RIFIN PF02009.16 CBY14236.1 - 0.17 11.8 16.5 0.32 10.9 16.5 1.3 1 0 0 1 1 1 0 Rifin Kelch_5 PF13854.6 CBY14236.1 - 2.4 8.2 0.0 2.4 8.2 0.0 5.1 6 0 0 6 6 6 0 Kelch motif Kelch_5 PF13854.6 CBY14238.1 - 0.00014 21.8 0.0 0.0099 15.8 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CBY14238.1 - 0.00059 19.7 3.5 0.79 9.8 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY14238.1 - 0.064 13.6 0.2 6.4 7.2 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Lectin_C PF00059.21 CBY14239.1 - 7.5e-21 74.9 7.9 1.1e-11 45.5 0.2 3.2 2 1 2 4 4 4 2 Lectin C-type domain Trefoil PF00088.18 CBY14239.1 - 0.016 15.0 5.0 0.043 13.7 5.0 1.7 1 0 0 1 1 1 0 Trefoil (P-type) domain AMMECR1 PF01871.17 CBY14241.1 - 1.2e-38 132.4 0.0 1.3e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 BTB PF00651.31 CBY14242.1 - 3.1e-12 46.7 0.2 4.6e-11 42.9 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain Synaptobrevin PF00957.21 CBY14243.1 - 1.4e-27 95.3 1.1 1.5e-27 95.2 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2951 PF11166.8 CBY14243.1 - 0.0062 16.7 0.1 0.0078 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2951) DUF5345 PF17280.2 CBY14243.1 - 0.02 14.8 0.4 0.027 14.5 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5345) DUF5129 PF17173.4 CBY14243.1 - 0.021 14.0 0.1 0.023 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) DUF2207 PF09972.9 CBY14243.1 - 0.051 12.3 0.0 0.051 12.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spore_III_AB PF09548.10 CBY14243.1 - 0.051 13.7 0.1 0.063 13.4 0.1 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF898 PF05987.13 CBY14243.1 - 0.051 12.6 0.0 0.058 12.4 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DotU PF09850.9 CBY14243.1 - 0.054 13.2 0.1 0.063 13.0 0.1 1.0 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF1514 PF07438.11 CBY14243.1 - 0.07 13.0 1.3 0.11 12.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) FeoB_associated PF12669.7 CBY14243.1 - 0.38 11.2 2.2 0.52 10.8 2.2 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein B9-C2 PF07162.11 CBY14245.1 - 9.2e-37 126.8 0.0 1e-36 126.7 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein BRE1 PF08647.11 CBY14246.1 - 7e-13 48.5 22.8 7e-13 48.5 22.8 10.7 3 3 6 10 10 10 2 BRE1 E3 ubiquitin ligase Filament PF00038.21 CBY14246.1 - 0.0032 17.1 8.0 0.0032 17.1 8.0 6.8 2 2 4 6 6 6 1 Intermediate filament protein AXIN1_TNKS_BD PF16646.5 CBY14246.1 - 0.96 10.4 4.0 0.84 10.6 0.2 3.1 2 1 0 2 2 2 0 Axin-1 tankyrase binding domain Rad1 PF02144.16 CBY14247.1 - 2.1e-22 79.5 0.4 2.4e-20 72.8 0.4 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Sas10_Utp3 PF04000.15 CBY14248.1 - 5.3e-11 43.0 0.0 1.4e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family FlaC_arch PF05377.11 CBY14248.1 - 0.03 14.7 1.9 0.04 14.3 0.4 2.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) MBOAT PF03062.19 CBY14249.1 - 1.4e-09 37.8 20.2 1.4e-09 37.8 20.2 2.3 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pep_deformylase PF01327.21 CBY14250.1 - 1.2e-20 73.8 0.1 4.6e-20 71.8 0.0 2.1 2 0 0 2 2 2 1 Polypeptide deformylase PH PF00169.29 CBY14250.1 - 4.1e-13 49.7 0.1 1.2e-12 48.2 0.1 1.9 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 CBY14250.1 - 4.6e-11 43.3 0.2 1.4e-10 41.8 0.2 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH_11 PF15413.6 CBY14250.1 - 0.057 13.8 0.3 0.29 11.6 0.3 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Anillin_N PF16018.5 CBY14250.1 - 0.41 11.3 2.6 4.3 8.0 0.6 3.1 2 0 0 2 2 2 0 Anillin N-terminus Pep_deformylase PF01327.21 CBY14251.1 - 5e-42 143.2 0.0 6.7e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase SET PF00856.28 CBY14252.1 - 2.7e-15 57.1 0.1 2.7e-15 57.1 0.1 4.4 3 2 0 3 3 3 1 SET domain FYRN PF05964.14 CBY14252.1 - 1.5e-11 44.0 0.0 3.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 CBY14252.1 - 2.8e-05 24.2 0.0 0.00015 21.9 0.0 2.3 1 0 0 1 1 1 1 F/Y rich C-terminus zf-HC5HC2H PF13771.6 CBY14252.1 - 0.00089 19.5 3.6 0.00089 19.5 3.6 4.3 2 1 2 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 CBY14252.1 - 0.11 12.4 53.4 0.0055 16.6 8.4 5.5 4 1 1 5 5 5 0 PHD-finger PHD_4 PF16866.5 CBY14252.1 - 0.36 11.0 17.2 0.18 11.9 7.8 3.6 1 1 1 2 2 2 0 PHD-finger Glycos_transf_2 PF00535.26 CBY14255.1 - 3.4e-11 43.3 0.0 4.7e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 RXLR_WY PF18634.1 CBY14255.1 - 0.03 14.3 0.0 0.68 9.9 0.0 2.7 3 1 0 3 3 3 0 RXLR phytopathogen effector protein WY-domain AARP2CN PF08142.12 CBY14256.1 - 0.00014 21.8 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AARP2CN PF08142.12 CBY14257.1 - 1.8e-22 79.2 0.0 1.3e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain ARHGEF5_35 PF15441.6 CBY14257.1 - 0.077 12.0 1.1 0.1 11.6 1.1 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 Sulfotransfer_4 PF17784.1 CBY14258.1 - 5.5e-46 157.1 0.1 7e-46 156.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY14258.1 - 0.0052 17.2 0.0 0.017 15.5 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family TSP_1 PF00090.19 CBY14259.1 - 9.2e-23 80.2 83.0 4.2e-08 33.3 9.2 5.6 6 1 0 6 6 6 4 Thrombospondin type 1 domain INTAP PF16617.5 CBY14259.1 - 0.28 11.5 5.9 0.16 12.3 0.3 3.0 2 1 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region Glyoxalase_4 PF13669.6 CBY14260.1 - 7.9e-06 26.1 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 CBY14260.1 - 0.018 15.2 0.2 0.055 13.7 0.1 1.9 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CUB PF00431.20 CBY14261.1 - 4.8e-08 33.3 1.9 1e-07 32.3 0.3 2.2 2 0 0 2 2 2 1 CUB domain Transket_pyr PF02779.24 CBY14263.1 - 1.4e-49 168.2 0.0 2.5e-49 167.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CBY14263.1 - 3.9e-43 146.8 0.0 6.5e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal PFOR_II PF17147.4 CBY14263.1 - 0.04 14.2 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II DUF1681 PF07933.14 CBY14264.1 - 3.9e-53 179.2 0.0 4.7e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Pkinase PF00069.25 CBY14265.1 - 2.7e-67 226.9 0.0 3.3e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14265.1 - 1.3e-33 116.4 0.0 2.2e-33 115.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY14265.1 - 1e-05 25.6 0.4 7.4e-05 22.8 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY14265.1 - 2.3e-05 23.5 0.1 2.3e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CBY14265.1 - 0.003 16.9 0.1 0.0049 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY14265.1 - 0.019 14.3 0.0 0.068 12.5 0.0 1.8 3 0 0 3 3 3 0 Kinase-like Apt1 PF10351.9 CBY14265.1 - 0.13 11.1 7.6 0.17 10.7 7.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase_fungal PF17667.1 CBY14265.1 - 0.59 8.8 2.7 0.73 8.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Glyco_hydro_63 PF03200.16 CBY14266.1 - 1.3e-181 604.7 0.8 1.4e-180 601.3 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CBY14266.1 - 3.3e-30 105.9 3.3 5.6e-30 105.1 3.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 CBY14266.1 - 0.0029 16.6 0.0 0.0053 15.8 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF2914 PF11141.8 CBY14266.1 - 0.14 11.9 0.6 0.41 10.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) TGF_beta PF00019.20 CBY14267.1 - 3.3e-31 108.3 1.3 3.3e-31 108.3 1.3 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain Homeodomain PF00046.29 CBY14270.1 - 1.1e-21 76.4 6.2 2.3e-21 75.4 6.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY14270.1 - 0.0031 17.4 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain Chordopox_A13L PF05961.11 CBY14270.1 - 1.4 9.2 3.8 1.1 9.5 1.8 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Trnau1ap PF17654.1 CBY14270.1 - 2.7 8.9 8.6 1.3 9.9 4.0 2.7 2 2 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins AlphaC_C PF17480.2 CBY14271.1 - 0.014 15.4 0.7 0.014 15.4 0.7 2.4 2 0 0 2 2 2 0 AlphaC C-terminal BRE1 PF08647.11 CBY14271.1 - 0.56 10.3 12.9 0.97 9.5 7.1 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 CBY14271.1 - 1.2 9.3 12.9 0.37 11.0 6.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SH3_1 PF00018.28 CBY14274.1 - 4.6e-14 51.8 1.7 1.2e-07 31.2 0.7 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CBY14274.1 - 1.3e-10 41.0 0.1 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CBY14274.1 - 4e-08 32.8 0.1 0.0001 21.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 CBY14274.1 - 0.0003 21.0 1.2 0.12 12.7 0.2 2.3 2 0 0 2 2 2 2 Bacterial SH3 domain NBP1 PF08537.10 CBY14274.1 - 0.00097 18.6 0.3 0.0017 17.8 0.3 1.3 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 SH3_16 PF18348.1 CBY14274.1 - 0.018 14.9 0.2 0.047 13.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain Imm61 PF15598.6 CBY14274.1 - 0.028 14.3 0.9 0.32 10.9 0.1 2.3 1 1 2 3 3 3 0 Immunity protein 61 DUF755 PF05501.11 CBY14276.1 - 0.17 12.1 5.2 0.29 11.4 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Kelch_2 PF07646.15 CBY14278.1 - 0.088 12.8 1.4 11 6.1 0.1 3.3 3 0 0 3 3 3 0 Kelch motif CCDC85 PF10226.9 CBY14278.1 - 0.2 11.3 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 CCDC85 family Kelch_5 PF13854.6 CBY14278.1 - 0.23 11.5 4.0 0.29 11.2 0.0 2.7 3 0 0 3 3 3 0 Kelch motif AWS PF17907.1 CBY14279.1 - 2.8 8.0 27.0 1 9.4 12.6 2.5 1 1 1 2 2 2 0 AWS domain Kelch_2 PF07646.15 CBY14280.1 - 4.2e-05 23.3 0.2 0.66 10.0 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY14280.1 - 0.0054 17.0 0.7 1.3 9.5 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CBY14280.1 - 0.23 11.5 4.2 4.8 7.3 0.0 3.2 3 0 0 3 3 3 0 Kelch motif DUF5122 PF17164.4 CBY14280.1 - 0.62 10.4 2.8 7.3 7.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Kelch_5 PF13854.6 CBY14281.1 - 0.004 17.1 2.0 0.0051 16.8 0.0 2.2 2 0 0 2 2 2 1 Kelch motif IL4 PF00727.18 CBY14281.1 - 0.086 13.1 0.7 0.14 12.4 0.7 1.2 1 0 0 1 1 1 0 Interleukin 4 Pkinase PF00069.25 CBY14284.1 - 5.2e-10 39.1 0.1 1e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14284.1 - 5.5e-06 25.9 0.1 9.7e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol_B_palm PF14792.6 CBY14285.1 - 0.12 12.6 0.3 0.25 11.5 0.3 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm SH3_9 PF14604.6 CBY14286.1 - 0.00017 21.3 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY14286.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 SH3 domain EamA PF00892.20 CBY14287.1 - 0.0029 17.8 46.1 0.0037 17.4 17.9 3.9 2 2 1 3 3 3 2 EamA-like transporter family DUF3938 PF13074.6 CBY14287.1 - 1.2 9.5 5.5 0.64 10.3 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) GNT-I PF03071.15 CBY14288.1 - 1.2e-88 297.7 2.4 1.4e-88 297.6 2.4 1.0 1 0 0 1 1 1 1 GNT-I family GNT-I PF03071.15 CBY14289.1 - 3.2e-09 36.1 0.0 3.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 GNT-I family Bap31 PF05529.12 CBY14290.1 - 1.6e-36 125.1 0.3 1.6e-36 125.1 0.3 1.8 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CBY14290.1 - 4.3e-11 42.6 25.0 3.7e-09 36.4 17.3 3.3 2 1 0 2 2 2 2 Bap31/Bap29 cytoplasmic coiled-coil domain Phage_holin_6_1 PF09682.10 CBY14290.1 - 0.019 15.4 4.0 0.038 14.4 3.6 1.7 1 1 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF4407 PF14362.6 CBY14290.1 - 0.023 14.0 12.2 0.035 13.5 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 CBY14290.1 - 0.029 12.6 7.4 0.035 12.3 7.4 1.0 1 0 0 1 1 1 0 Hsp70 protein Urate_ox_N PF06181.11 CBY14290.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Urate oxidase N-terminal HAUS6_N PF14661.6 CBY14290.1 - 0.091 12.3 9.6 0.12 12.0 9.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.15 CBY14290.1 - 0.1 12.1 5.6 0.12 11.9 5.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PIN_8 PF18476.1 CBY14290.1 - 0.22 11.3 8.7 0.35 10.7 8.7 1.3 1 0 0 1 1 1 0 PIN like domain OAD_gamma PF04277.13 CBY14290.1 - 0.5 11.0 10.3 0.74 10.4 1.2 3.3 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DASH_Ask1 PF08655.10 CBY14290.1 - 0.51 10.3 3.3 3.4 7.6 0.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Ask1 ADIP PF11559.8 CBY14290.1 - 0.66 10.0 18.3 1.1 9.4 18.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MRP-S26 PF14943.6 CBY14290.1 - 0.88 9.5 17.1 1.7 8.5 17.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 FapA PF03961.13 CBY14290.1 - 1.4 7.5 9.5 1.8 7.1 9.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Zip PF02535.22 CBY14290.1 - 1.4 8.0 3.6 2.5 7.2 3.6 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Jnk-SapK_ap_N PF09744.9 CBY14290.1 - 1.6 8.9 18.3 2.8 8.1 18.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Fzo_mitofusin PF04799.13 CBY14290.1 - 1.8 8.1 8.0 3 7.4 8.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region Sugarporin_N PF11471.8 CBY14290.1 - 2 8.5 19.5 2 8.4 2.7 3.5 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension PIEZO PF15917.5 CBY14290.1 - 4.8 6.6 13.0 8 5.9 13.0 1.6 1 1 0 1 1 1 0 Piezo BST2 PF16716.5 CBY14290.1 - 5.8 7.6 18.5 3.3 8.4 12.6 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Ly49 PF08391.10 CBY14290.1 - 5.9 7.3 6.8 53 4.2 6.2 2.5 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region UPF0242 PF06785.11 CBY14290.1 - 6.9 6.7 18.6 12 5.9 18.6 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HisKA_3 PF07730.13 CBY14290.1 - 7.9 7.1 10.1 67 4.1 8.4 2.8 1 1 1 2 2 2 0 Histidine kinase Spc7 PF08317.11 CBY14290.1 - 8.6 5.1 22.7 7.2 5.4 21.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein zf-C2H2 PF00096.26 CBY14291.1 - 1.3e-11 44.3 25.7 0.0018 18.6 0.5 6.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY14291.1 - 0.00044 20.8 34.4 0.0022 18.7 0.3 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBY14291.1 - 0.0039 16.8 0.2 0.0039 16.8 0.2 4.8 3 1 1 5 5 5 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 CBY14291.1 - 0.0097 16.3 15.5 2 9.0 0.2 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBY14291.1 - 0.025 14.3 21.4 0.7 9.7 1.4 5.4 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-met PF12874.7 CBY14291.1 - 0.064 13.7 0.3 0.064 13.7 0.3 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF1610 PF07754.11 CBY14291.1 - 0.3 11.1 1.9 0.58 10.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-C2H2 PF00096.26 CBY14292.1 - 0.00027 21.2 42.6 0.0028 18.0 0.9 6.9 7 1 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY14292.1 - 0.0015 19.2 0.7 0.0015 19.2 0.7 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.7 CBY14292.1 - 0.0022 18.3 4.6 0.0062 16.9 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 CBY14292.1 - 0.0022 17.6 0.2 0.0022 17.6 0.2 4.8 3 1 2 5 5 5 1 Zinc-fingers and homeoboxes C2H2 finger domain A2L_zn_ribbon PF08792.10 CBY14292.1 - 0.0044 16.7 0.1 0.0044 16.7 0.1 3.0 3 0 0 3 3 3 1 A2L zinc ribbon domain zf-C2H2_jaz PF12171.8 CBY14292.1 - 0.011 16.0 0.9 0.011 16.0 0.9 3.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding NID PF07292.13 CBY14292.1 - 0.025 15.2 0.4 1.8 9.2 0.0 3.0 2 1 0 3 3 3 0 Nmi/IFP 35 domain (NID) zf-C2H2_11 PF16622.5 CBY14292.1 - 0.032 14.0 0.2 0.032 14.0 0.2 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY14292.1 - 0.032 14.2 0.3 0.032 14.2 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CBY14292.1 - 1 9.4 0.1 1 9.4 0.1 3.6 3 1 0 3 3 3 0 zinc-finger of a C2HC-type SDF PF00375.18 CBY14294.1 - 2.3e-32 112.5 4.1 2.8e-32 112.2 4.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Toprim_Crpt PF13342.6 CBY14295.1 - 0.018 15.0 1.2 0.077 13.0 0.3 2.1 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase HSF_DNA-bind PF00447.17 CBY14296.1 - 8.8e-13 48.7 1.1 1.8e-12 47.7 1.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding DUF5344 PF17279.2 CBY14296.1 - 0.34 11.5 3.5 5 7.8 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Striatin PF08232.12 CBY14296.1 - 9.4 6.8 11.3 2.9 8.5 3.6 2.3 1 1 1 2 2 2 0 Striatin family POLO_box PF00659.18 CBY14300.1 - 0.046 13.9 1.5 2 8.6 0.0 2.6 1 1 1 2 2 2 0 POLO box duplicated region CKS PF01111.19 CBY14300.1 - 0.046 14.0 0.2 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit Prok-E2_E PF14462.6 CBY14300.1 - 0.11 12.3 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family E Lipase_3 PF01764.25 CBY14301.1 - 1.7e-19 70.1 0.0 3.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBY14301.1 - 1.9e-05 25.4 0.0 2.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 CBY14301.1 - 6e-05 22.7 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CBY14301.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.8 CBY14301.1 - 0.0024 17.5 0.0 0.0098 15.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 CBY14301.1 - 0.0027 17.5 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY14301.1 - 0.0047 17.1 0.0 0.011 15.9 0.0 1.6 1 1 1 2 2 2 1 Thioesterase domain Lipase_2 PF01674.18 CBY14301.1 - 0.0055 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Hydrolase_4 PF12146.8 CBY14301.1 - 0.014 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY14301.1 - 0.017 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CBY14301.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HNF-1_N PF04814.13 CBY14302.1 - 1.2e-60 205.4 2.7 1.6e-60 205.1 2.7 1.1 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus HTH_3 PF01381.22 CBY14302.1 - 0.033 14.3 0.8 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix TAL_effector PF03377.13 CBY14302.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 TAL effector repeat DUF2721 PF11026.8 CBY14302.1 - 0.14 12.1 0.4 0.25 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF730 PF05325.11 CBY14304.1 - 0.39 10.7 2.7 6.6 6.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF730) V_ATPase_I PF01496.19 CBY14306.1 - 0.0096 13.9 4.9 0.011 13.7 4.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CPSF100_C PF13299.6 CBY14306.1 - 0.93 9.7 8.4 2.1 8.5 8.4 1.6 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal zf_ZIC PF18366.1 CBY14306.1 - 8.4 6.6 6.1 2.6 8.2 0.2 2.9 4 0 0 4 4 4 0 Zic proteins zinc finger domain Presenilin PF01080.17 CBY14306.1 - 8.9 5.0 7.0 9.8 4.8 7.0 1.1 1 0 0 1 1 1 0 Presenilin Gal_Lectin PF02140.18 CBY14307.1 - 6.8e-20 71.3 11.3 3.3e-13 49.9 4.4 2.8 3 0 0 3 3 3 2 Galactose binding lectin domain Mito_carr PF00153.27 CBY14308.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein V_ATPase_I PF01496.19 CBY14310.1 - 0.0096 13.9 4.9 0.011 13.7 4.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CPSF100_C PF13299.6 CBY14310.1 - 0.93 9.7 8.4 2.1 8.5 8.4 1.6 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal zf_ZIC PF18366.1 CBY14310.1 - 8.4 6.6 6.1 2.6 8.2 0.2 2.9 4 0 0 4 4 4 0 Zic proteins zinc finger domain Presenilin PF01080.17 CBY14310.1 - 8.9 5.0 7.0 9.8 4.8 7.0 1.1 1 0 0 1 1 1 0 Presenilin Gal_Lectin PF02140.18 CBY14311.1 - 6.8e-20 71.3 11.3 3.3e-13 49.9 4.4 2.8 3 0 0 3 3 3 2 Galactose binding lectin domain DUF1993 PF09351.10 CBY14312.1 - 0.071 13.2 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Mito_carr PF00153.27 CBY14312.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein NADH_B2 PF14813.6 CBY14313.1 - 0.016 14.9 0.9 0.075 12.8 0.9 2.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 OSK PF17182.4 CBY14313.1 - 0.066 12.4 0.0 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 OSK domain CDV3 PF15359.6 CBY14313.1 - 0.17 12.4 0.8 0.39 11.2 0.8 1.6 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 zinc_ribbon_9 PF14369.6 CBY14313.1 - 5.2 7.4 7.3 10 6.5 0.6 2.6 2 0 0 2 2 2 0 zinc-ribbon PITH PF06201.13 CBY14314.1 - 5e-38 130.7 0.0 6.1e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sec23_trunk PF04811.15 CBY14315.1 - 4.7e-70 235.9 0.0 6.6e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CBY14315.1 - 1.4e-14 54.6 0.0 2.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CBY14315.1 - 1.5e-12 47.3 3.7 3.2e-12 46.3 3.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CBY14315.1 - 1.7e-05 24.6 0.0 4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Paz_1 PF18349.1 CBY14315.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 PAZ domain Peptidase_C78 PF07910.13 CBY14316.1 - 3.4e-47 160.7 0.1 5.7e-47 159.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CBY14316.1 - 0.0026 17.2 2.0 0.13 11.6 0.6 2.8 1 1 1 2 2 2 2 Peptidase family C54 Sterile PF03015.19 CBY14316.1 - 0.05 13.8 0.8 0.37 11.0 0.0 2.6 3 0 0 3 3 3 0 Male sterility protein DUF441 PF04284.13 CBY14317.1 - 0.0058 16.6 1.1 0.0092 16.0 0.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF441) BTB PF00651.31 CBY14318.1 - 1.8e-15 57.2 0.5 4.2e-15 55.9 0.5 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF5623 PF18536.1 CBY14318.1 - 0.093 13.0 0.2 5.7 7.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) Pkinase PF00069.25 CBY14319.1 - 9.6e-32 110.4 0.0 2.3e-30 105.8 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14319.1 - 3.1e-18 66.0 0.0 1e-17 64.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY14319.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4131 PF13567.6 CBY14320.1 - 0.62 9.7 2.8 0.62 9.7 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MGC-24 PF05283.11 CBY14320.1 - 1.7 9.1 12.2 1.9 8.9 8.6 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Tetraspanin PF00335.20 CBY14320.1 - 5.5 6.6 10.6 54 3.4 11.3 2.2 1 1 0 1 1 1 0 Tetraspanin family MBD_C PF14048.6 CBY14321.1 - 3.5e-20 72.5 0.2 5.1e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 DFP PF04127.15 CBY14322.1 - 3.7e-18 66.0 0.0 1.1e-14 54.7 0.0 2.1 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein adh_short PF00106.25 CBY14323.1 - 2.3e-15 56.6 0.1 5e-12 45.7 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 CBY14323.1 - 3.8e-07 30.2 0.0 7.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CBY14323.1 - 8.2e-05 22.3 0.0 0.0037 16.8 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 CBY14323.1 - 0.021 14.0 0.0 0.048 12.8 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 CBY14323.1 - 0.17 12.0 0.0 0.61 10.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Torus PF16131.5 CBY14324.1 - 3.1e-05 24.6 0.3 0.00014 22.6 0.3 2.1 1 0 0 1 1 1 1 Torus domain PDDEXK_5 PF11645.8 CBY14324.1 - 0.092 12.7 0.1 0.15 12.0 0.1 1.4 1 1 0 1 1 1 0 PD-(D/E)XK endonuclease Ly49 PF08391.10 CBY14324.1 - 0.16 12.3 1.7 0.3 11.5 0.1 2.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Dimer_Tnp_hAT PF05699.14 CBY14325.1 - 1.3e-05 24.9 0.2 2.3e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CRISPR_Cas2 PF09827.9 CBY14326.1 - 0.017 15.3 0.2 0.023 14.9 0.2 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Wbp11 PF09429.10 CBY14326.1 - 0.037 14.4 2.8 0.072 13.5 2.8 1.6 1 1 0 1 1 1 0 WW domain binding protein 11 TBCC_N PF16752.5 CBY14327.1 - 0.0092 16.4 6.3 1.7 9.1 0.1 2.5 2 0 0 2 2 2 2 Tubulin-specific chaperone C N-terminal domain DUF848 PF05852.11 CBY14327.1 - 9.4 6.3 9.9 7.5 6.7 5.5 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FerA PF08165.11 CBY14328.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 FerA (NUC095) domain Rad60-SLD PF11976.8 CBY14329.1 - 1.5e-09 37.6 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY14329.1 - 1.5e-05 24.6 0.6 5e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family ATG16 PF08614.11 CBY14329.1 - 0.00039 20.7 4.2 0.00039 20.7 4.2 1.8 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) CENP-H PF05837.12 CBY14329.1 - 0.024 15.0 7.3 0.05 14.0 7.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF1663 PF07909.11 CBY14329.1 - 0.16 10.7 2.1 0.23 10.1 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) Peptidase_C57 PF03290.13 CBY14329.1 - 1.2 7.8 4.6 0.28 9.9 1.5 1.4 2 0 0 2 2 2 0 Vaccinia virus I7 processing peptidase AAA PF00004.29 CBY14330.1 - 3.4e-40 137.5 0.0 8e-40 136.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CBY14330.1 - 1.3e-12 47.5 0.2 1.7e-11 44.0 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CBY14330.1 - 4.3e-09 36.0 0.1 5.6e-08 32.5 0.1 2.7 1 1 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CBY14330.1 - 3.5e-05 23.6 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBY14330.1 - 0.00019 21.6 0.0 0.00051 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CBY14330.1 - 0.00033 20.8 0.0 0.00098 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CBY14330.1 - 0.00074 18.8 0.0 0.0023 17.2 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 CBY14330.1 - 0.0022 18.0 0.1 0.019 14.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY14330.1 - 0.0022 18.4 0.0 0.0064 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY14330.1 - 0.0032 17.7 0.1 0.11 12.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 CBY14330.1 - 0.0034 17.4 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CBY14330.1 - 0.0056 16.1 0.3 0.017 14.5 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBY14330.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CBY14330.1 - 0.017 15.1 0.0 0.056 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 CBY14330.1 - 0.018 13.7 1.0 0.023 13.3 1.0 1.3 1 0 0 1 1 1 0 Macoilin family AAA_7 PF12775.7 CBY14330.1 - 0.025 14.1 0.2 0.11 12.0 0.1 2.0 1 1 1 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 CBY14330.1 - 0.028 15.0 0.6 0.17 12.4 0.4 2.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY14330.1 - 0.029 14.7 0.0 0.094 13.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 CBY14330.1 - 0.047 13.0 0.0 1.8 7.9 0.1 2.5 1 1 1 2 2 2 0 KaiC Ndc1_Nup PF09531.10 CBY14330.1 - 0.064 12.0 3.9 0.082 11.6 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PhoH PF02562.16 CBY14330.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CBY14330.1 - 0.1 12.3 0.0 0.53 10.0 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 CBY14330.1 - 0.13 12.2 0.1 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 CBY14330.1 - 0.14 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CBY14330.1 - 0.16 11.2 1.2 0.16 11.2 0.1 1.6 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) Cytochrom_B562 PF07361.11 CBY14330.1 - 0.43 11.3 3.0 0.54 10.9 0.1 2.6 3 0 0 3 3 2 0 Cytochrome b562 AAA_11 PF13086.6 CBY14330.1 - 0.74 9.6 8.7 0.13 12.0 0.7 2.5 2 1 0 2 2 2 0 AAA domain Lactamase_B_2 PF12706.7 CBY14331.1 - 2.4e-17 63.1 0.0 4.2e-07 29.7 0.0 3.0 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBY14331.1 - 1.7e-10 41.2 0.0 2.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 CBY14331.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease DOMON PF03351.17 CBY14332.1 - 1.3e-12 48.0 0.3 2e-12 47.4 0.3 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 CBY14332.1 - 2.9e-08 33.9 1.2 2.9e-08 33.9 1.2 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 CBY14332.1 - 0.0014 18.6 2.7 0.0014 18.6 2.7 2.5 1 1 1 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 CBY14332.1 - 0.009 15.9 0.1 0.009 15.9 0.1 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family ODV-E18 PF10717.9 CBY14332.1 - 0.1 12.5 0.8 0.31 11.0 0.1 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF4079 PF13301.6 CBY14332.1 - 0.26 11.4 6.5 0.039 14.1 2.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 CBY14332.1 - 0.36 10.4 12.4 3.1 7.4 12.1 2.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 CD20 PF04103.15 CBY14332.1 - 0.64 10.1 7.3 1.8 8.6 0.1 3.0 3 0 0 3 3 3 0 CD20-like family DUF2427 PF10348.9 CBY14332.1 - 9.9 6.0 16.1 19 5.1 6.5 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF2427) XK-related PF09815.9 CBY14333.1 - 3.2e-89 299.3 30.8 3.8e-89 299.1 30.8 1.1 1 0 0 1 1 1 1 XK-related protein Sarcoglycan_2 PF05510.13 CBY14333.1 - 0.0031 16.4 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Orf78 PF06024.12 CBY14333.1 - 0.022 15.1 0.7 0.15 12.4 0.3 2.6 2 0 0 2 2 2 0 Orf78 (ac78) DUF4131 PF13567.6 CBY14333.1 - 1.9 8.1 10.5 0.48 10.1 1.4 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) UBX PF00789.20 CBY14334.1 - 3.8e-09 36.6 0.0 1e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CBY14334.1 - 1.7e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CBY14334.1 - 0.038 13.6 0.1 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 TAP C-terminal domain AAA_23 PF13476.6 CBY14334.1 - 3.1 8.2 9.1 6.9 7.1 9.1 1.6 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 CBY14335.1 - 3.1e-06 26.8 0.0 0.00049 19.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY14335.1 - 0.012 15.2 0.0 0.42 10.1 0.0 2.0 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase HU-CCDC81_euk_1 PF14908.6 CBY14337.1 - 3e-13 49.7 0.3 2e-12 47.1 0.0 2.3 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 CBY14337.1 - 1.4e-06 28.4 0.2 4.2e-06 26.8 0.1 1.8 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 Bac_DNA_binding PF00216.21 CBY14337.1 - 0.0001 22.4 1.6 0.063 13.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial DNA-binding protein Sushi PF00084.20 CBY14339.1 - 0.12 12.9 1.2 0.19 12.3 0.1 2.0 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) DUF5316 PF17247.2 CBY14339.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5316) Galactosyl_T PF01762.21 CBY14340.1 - 4.5e-21 75.6 0.0 7.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase E1_dh PF00676.20 CBY14341.1 - 7.3e-72 241.8 0.0 1e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CBY14341.1 - 3.8e-53 179.8 0.0 8e-53 178.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CBY14341.1 - 5.1e-51 172.4 0.0 1e-50 171.4 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CBY14341.1 - 4e-18 64.7 0.4 1e-17 63.4 0.4 1.8 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus 2OG-FeII_Oxy_2 PF13532.6 CBY14342.1 - 3.8e-16 59.9 0.0 4.8e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Intein_splicing PF14890.6 CBY14342.1 - 0.083 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Intein splicing domain Ras PF00071.22 CBY14345.1 - 1.2e-58 197.3 0.5 1.4e-58 197.0 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY14345.1 - 3.2e-36 124.2 0.2 5.1e-36 123.5 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY14345.1 - 1.1e-15 57.5 0.3 1.4e-15 57.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY14345.1 - 5.1e-07 29.4 0.2 2.9e-06 27.0 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBY14345.1 - 2e-05 24.1 0.1 3.2e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CBY14345.1 - 2e-05 24.2 0.3 0.00044 19.8 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CBY14345.1 - 2.6e-05 24.3 0.1 3.9e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY14345.1 - 4e-05 23.6 0.1 0.025 14.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBY14345.1 - 0.00012 21.5 0.3 0.00015 21.2 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 CBY14345.1 - 0.0057 16.5 0.1 0.016 15.0 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TIR_2 PF13676.6 CBY14345.1 - 0.055 14.1 0.1 0.09 13.4 0.1 1.3 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 CBY14345.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 CBY14345.1 - 0.18 10.9 1.1 5.8 6.0 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Arm PF00514.23 CBY14346.1 - 4.5e-37 125.0 25.3 5.7e-10 38.9 0.0 9.6 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CBY14346.1 - 2.5e-14 53.6 2.9 0.019 15.0 0.1 5.1 2 1 3 5 5 5 5 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY14346.1 - 3.3e-14 53.0 10.7 0.001 19.4 0.7 5.9 1 1 6 7 7 7 6 HEAT repeats HEAT PF02985.22 CBY14346.1 - 4.8e-14 51.3 8.5 0.11 12.9 0.1 7.8 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 CBY14346.1 - 1e-09 38.7 22.2 0.00073 20.0 1.0 6.8 6 2 3 9 9 7 5 HEAT-like repeat Adaptin_N PF01602.20 CBY14346.1 - 2.7e-08 32.8 9.1 0.002 16.8 1.6 3.5 1 1 1 3 3 3 3 Adaptin N terminal region DNA_alkylation PF08713.11 CBY14346.1 - 3.2e-07 30.3 0.2 2.2 8.0 0.0 4.0 2 1 0 3 3 3 3 DNA alkylation repair enzyme CHASE6_C PF17150.4 CBY14346.1 - 6.3e-07 30.0 2.7 1.1 9.9 0.1 6.6 6 3 2 8 8 8 1 C-terminal domain of two-partite extracellular sensor domain RICTOR_V PF14668.6 CBY14346.1 - 3.3e-06 27.2 0.1 1.6 9.0 0.0 4.4 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_N PF14664.6 CBY14346.1 - 0.00015 20.9 3.3 0.0011 18.0 1.0 3.0 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Proteasom_PSMB PF10508.9 CBY14346.1 - 0.00016 20.3 6.1 0.0096 14.5 1.1 3.2 1 1 2 3 3 3 2 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 CBY14346.1 - 0.00044 20.3 1.8 0.86 9.7 0.0 4.1 4 0 0 4 4 4 1 V-ATPase subunit H Mo25 PF08569.11 CBY14346.1 - 0.00093 18.6 2.5 0.096 12.0 0.2 2.8 2 1 1 3 3 3 2 Mo25-like Arm_2 PF04826.13 CBY14346.1 - 0.0028 17.2 0.8 2.7 7.4 0.0 3.8 1 1 3 4 4 4 1 Armadillo-like HEAT_PBS PF03130.16 CBY14346.1 - 0.0032 18.0 6.5 4.7 8.2 0.3 5.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat API5 PF05918.11 CBY14346.1 - 0.0064 15.4 6.6 0.9 8.3 0.3 3.9 2 1 1 4 4 4 2 Apoptosis inhibitory protein 5 (API5) DUF3731 PF12531.8 CBY14346.1 - 0.028 14.2 4.5 17 5.1 0.1 3.4 3 1 0 3 3 3 0 DNA-K related protein COMMD1_N PF17221.3 CBY14346.1 - 0.094 13.0 0.6 7.6 6.9 0.0 3.2 3 0 0 3 3 3 0 COMMD1 N-terminal domain MMS19_C PF12460.8 CBY14346.1 - 0.21 10.7 9.4 0.57 9.2 0.4 3.7 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal MIP PF00230.20 CBY14347.1 - 8.8e-39 133.5 11.3 1.3e-38 133.0 11.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein CRT10 PF08728.10 CBY14347.1 - 0.0022 16.3 0.1 0.003 15.8 0.1 1.1 1 0 0 1 1 1 1 CRT10 DUF5637 PF18687.1 CBY14347.1 - 0.097 12.7 1.8 0.24 11.4 1.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5637) DUF2093 PF09866.9 CBY14347.1 - 1.6 8.2 4.8 11 5.5 0.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) bZIP_2 PF07716.15 CBY14348.1 - 1.8e-16 60.0 8.5 1.8e-16 60.0 8.5 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY14348.1 - 2.2e-07 30.9 7.1 4.6e-07 29.8 7.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor Herpes_LMP1 PF05297.11 CBY14350.1 - 0.1 11.8 0.9 0.16 11.1 0.9 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Macoilin PF09726.9 CBY14350.1 - 0.29 9.6 9.4 0.36 9.3 9.4 1.1 1 0 0 1 1 1 0 Macoilin family T4_deiodinase PF00837.17 CBY14354.1 - 9.3e-29 100.4 0.0 1e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Scramblase PF03803.15 CBY14357.1 - 1.4e-18 67.0 0.0 2.4e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Scramblase ILEI PF15711.5 CBY14358.1 - 6.5e-21 74.6 0.1 1.1e-20 73.8 0.1 1.4 1 0 0 1 1 1 1 Interleukin-like EMT inducer zf-RRN7 PF11781.8 CBY14359.1 - 0.02 14.6 0.9 0.04 13.6 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Auto_anti-p27 PF06677.12 CBY14359.1 - 0.2 11.9 1.2 0.38 10.9 1.2 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) COX6B PF02297.17 CBY14360.1 - 7.9e-11 42.0 1.1 1.4e-10 41.3 1.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pkinase_Tyr PF07714.17 CBY14361.1 - 2.2e-38 132.0 0.0 2.5e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY14361.1 - 6.3e-27 94.6 0.0 7.3e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY14361.1 - 7e-05 22.3 0.0 7.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like ITI_HC_C PF06668.12 CBY14362.1 - 6.6e-05 22.6 0.0 0.00041 20.1 0.0 2.4 2 0 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus zf-C2H2_2 PF12756.7 CBY14363.1 - 0.067 13.5 0.6 0.15 12.4 0.6 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CBY14363.1 - 0.33 11.5 2.2 0.49 10.9 1.0 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Med13_C PF06333.12 CBY14365.1 - 1.3e-47 162.7 0.6 2.4e-47 161.8 0.6 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 CBY14365.1 - 5.5e-15 55.8 0.8 1.3e-14 54.7 0.1 2.0 2 0 0 2 2 2 1 MID domain of medPIWI Med13_N PF11597.8 CBY14366.1 - 5.7e-12 45.7 0.0 1.4e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Zip PF02535.22 CBY14367.1 - 2e-19 70.0 16.2 1.1e-18 67.5 3.2 2.5 1 1 1 2 2 2 2 ZIP Zinc transporter HlyIII PF03006.20 CBY14367.1 - 0.067 12.9 3.8 0.1 12.3 0.9 2.3 2 0 0 2 2 2 0 Haemolysin-III related DUF4293 PF14126.6 CBY14367.1 - 0.096 12.9 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) MerC PF03203.14 CBY14367.1 - 0.74 10.3 9.0 0.04 14.4 2.0 2.4 2 1 1 3 3 3 0 MerC mercury resistance protein PDZ PF00595.24 CBY14368.1 - 2.2e-85 281.1 3.9 1.6e-13 50.8 0.0 8.9 9 0 0 9 9 9 8 PDZ domain PDZ_6 PF17820.1 CBY14368.1 - 4.3e-85 279.5 16.1 1.6e-12 47.1 0.0 8.3 8 0 0 8 8 8 8 PDZ domain PDZ_2 PF13180.6 CBY14368.1 - 2.1e-41 140.1 12.4 3.2e-07 30.6 0.0 8.4 8 0 0 8 8 8 7 PDZ domain Tetraspanin PF00335.20 CBY14368.1 - 6.4e-09 35.9 7.1 9.6e-09 35.3 7.1 1.2 1 0 0 1 1 1 1 Tetraspanin family Tricorn_PDZ PF14685.6 CBY14368.1 - 1.9e-06 27.7 10.8 0.39 10.7 0.0 6.8 7 0 0 7 7 7 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 CBY14368.1 - 0.00023 21.5 2.4 1.2 9.6 0.0 5.3 4 2 2 6 6 6 1 PDZ domain RPAP1_C PF08620.10 CBY14368.1 - 0.018 15.1 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 RPAP1-like, C-terminal Syndecan PF01034.20 CBY14370.1 - 3.7e-08 33.2 0.3 4.5e-08 32.9 0.3 1.1 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 CBY14370.1 - 0.0024 18.1 0.0 0.0028 17.9 0.0 1.1 1 0 0 1 1 1 1 Glycophorin A CbtA PF09490.10 CBY14370.1 - 0.065 13.0 0.4 0.084 12.6 0.4 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Podoplanin PF05808.11 CBY14370.1 - 0.11 12.6 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Podoplanin Protocadherin PF08374.11 CBY14370.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protocadherin COesterase PF00135.28 CBY14372.1 - 2e-72 244.8 0.0 3.9e-72 243.8 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY14372.1 - 1.9e-08 34.4 0.2 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY14372.1 - 0.0016 17.9 0.1 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family SPATA3 PF15662.5 CBY14373.1 - 2.3 8.8 6.2 2.8 8.5 6.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Ndc1_Nup PF09531.10 CBY14373.1 - 2.8 6.5 5.3 3 6.4 5.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lipocalin_2 PF08212.12 CBY14374.1 - 5.9e-12 45.7 1.2 8.3e-12 45.3 1.2 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY14374.1 - 1.6e-07 31.6 0.1 5.7e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family VDE PF07137.11 CBY14374.1 - 0.18 11.3 1.1 1 8.9 1.1 2.0 1 1 0 1 1 1 0 VDE lipocalin domain CUB PF00431.20 CBY14375.1 - 2.2e-11 44.1 0.0 4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 CUB domain zf-C3HC4_3 PF13920.6 CBY14376.1 - 1.6e-07 31.0 11.0 2.1e-07 30.7 11.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY14376.1 - 3.1e-07 30.3 13.1 3.9e-07 29.9 13.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY14376.1 - 4.8e-06 26.8 13.1 6.4e-06 26.4 13.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY14376.1 - 4.2e-05 23.3 12.3 7.5e-05 22.5 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY14376.1 - 8.3e-05 22.5 6.2 8.3e-05 22.5 6.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY14376.1 - 0.00012 21.8 12.2 0.00018 21.3 12.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY14376.1 - 0.0014 18.3 5.7 0.0014 18.3 5.7 1.9 1 1 1 2 2 2 1 RING-like zinc finger zf-RING_6 PF14835.6 CBY14376.1 - 0.0045 16.8 6.4 0.0057 16.5 6.4 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CBY14376.1 - 0.0071 16.5 7.4 0.0085 16.2 7.4 1.2 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CBY14376.1 - 0.048 13.5 13.9 0.15 12.0 13.9 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY14376.1 - 0.068 13.0 11.8 0.19 11.6 11.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CBY14376.1 - 0.25 11.6 13.8 8.4 6.8 13.8 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY14376.1 - 0.63 10.1 9.3 3.9 7.6 9.3 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sulfotransfer_1 PF00685.27 CBY14378.1 - 8e-10 38.6 0.8 3.9e-08 33.1 0.3 2.2 1 1 0 2 2 2 2 Sulfotransferase domain WSC PF01822.19 CBY14378.1 - 1.8e-06 28.0 1.6 3.7e-06 27.0 1.6 1.6 1 0 0 1 1 1 1 WSC domain Sulfotransfer_3 PF13469.6 CBY14378.1 - 0.0075 16.7 0.0 0.021 15.2 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family BET PF17035.5 CBY14378.1 - 0.31 11.3 1.3 9.5 6.5 0.2 2.3 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Phospholip_A2_1 PF00068.19 CBY14379.1 - 1.7e-12 47.8 6.4 1.7e-12 47.8 6.4 1.6 2 0 0 2 2 2 1 Phospholipase A2 UPF0184 PF03670.13 CBY14379.1 - 0.07 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF2089 PF09862.9 CBY14380.1 - 0.0055 16.7 2.4 0.0055 16.7 2.4 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2089) DIT1_PvcA PF05141.12 CBY14380.1 - 0.12 11.8 3.2 0.16 11.4 3.2 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF1690 PF07956.11 CBY14380.1 - 0.19 12.1 12.2 0.34 11.3 12.2 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF3826 PF12875.7 CBY14380.1 - 0.31 11.2 9.3 0.46 10.6 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) DUF4407 PF14362.6 CBY14380.1 - 0.46 9.8 11.6 1.3 8.3 12.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 CBY14380.1 - 3.1 7.3 11.3 3.3 7.2 3.4 2.4 2 1 1 3 3 3 0 fzo-like conserved region FAM76 PF16046.5 CBY14380.1 - 3.6 6.9 8.9 5.7 6.2 8.9 1.3 1 0 0 1 1 1 0 FAM76 protein Phlebovirus_NSM PF07246.11 CBY14380.1 - 4.1 6.7 11.4 6 6.2 11.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1192 PF06698.11 CBY14380.1 - 5.6 7.1 10.6 1.9 8.6 2.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ras PF00071.22 CBY14381.1 - 2.7e-53 179.9 0.0 3.2e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY14381.1 - 7.5e-23 81.0 0.0 1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY14381.1 - 6.1e-06 25.8 0.0 9.6e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CBY14381.1 - 0.047 13.4 0.1 0.89 9.3 0.1 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Nup35_RRM_2 PF14605.6 CBY14382.1 - 0.0022 18.0 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBY14382.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBY14382.1 - 0.033 14.0 0.1 0.071 12.9 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LPD15 PF18828.1 CBY14382.1 - 0.041 13.7 0.5 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 Ima1_N PF09779.9 CBY14382.1 - 1.5 9.7 4.9 0.58 11.0 0.6 2.2 1 1 1 2 2 2 0 Ima1 N-terminal domain FERM_M PF00373.18 CBY14383.1 - 2.8e-16 60.0 0.5 9.4e-16 58.3 0.1 1.9 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 CBY14383.1 - 4.7e-14 52.5 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CBY14383.1 - 1.2e-11 44.3 0.6 1.1e-10 41.3 0.3 2.3 2 0 0 2 2 2 1 FERM N-terminal domain EVI2A PF05399.11 CBY14384.1 - 2.2 7.8 9.9 1.4 8.4 5.4 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) FA_desaturase PF00487.24 CBY14385.1 - 6.2e-22 78.7 17.2 5.2e-11 42.9 4.8 2.4 2 1 1 3 3 3 2 Fatty acid desaturase Lipid_DES PF08557.10 CBY14385.1 - 3.6e-18 64.7 0.1 8.6e-18 63.5 0.1 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) HXXEE PF13787.6 CBY14385.1 - 0.47 11.3 4.1 0.48 11.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Dynein_C PF18199.1 CBY14386.1 - 7e-92 307.9 0.0 7.8e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Phospholip_A2_1 PF00068.19 CBY14388.1 - 1.7e-09 38.1 0.8 1.7e-09 38.1 0.8 2.2 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY14389.1 - 1.2e-14 54.7 5.6 1.2e-14 54.7 5.6 2.1 2 0 0 2 2 2 1 Phospholipase A2 Pox_LP_H2 PF03356.15 CBY14389.1 - 0.12 12.2 1.0 0.3 10.9 1.0 1.6 1 1 0 1 1 1 0 Viral late protein H2 KH_1 PF00013.29 CBY14390.1 - 1.2e-14 53.9 0.7 2e-14 53.1 0.2 1.7 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 CBY14390.1 - 0.001 18.8 3.7 0.0029 17.4 3.7 1.8 1 1 0 1 1 1 1 KH domain KH_4 PF13083.6 CBY14390.1 - 0.012 15.5 0.5 0.037 13.9 0.0 2.0 2 0 0 2 2 2 0 KH domain DUF3420 PF11900.8 CBY14390.1 - 0.038 14.1 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) GPW_gp25 PF04965.14 CBY14390.1 - 0.04 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Gene 25-like lysozyme SLS PF14611.6 CBY14390.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.29 CBY14391.1 - 5.5e-25 87.0 1.8 3.9e-14 52.2 0.2 2.2 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBY14391.1 - 1.8e-07 30.9 2.1 0.0024 17.7 0.5 2.5 1 1 1 2 2 2 2 KH domain KH_4 PF13083.6 CBY14391.1 - 0.072 13.0 0.6 1.7 8.6 0.1 2.7 2 1 1 3 3 3 0 KH domain Pyrophosphatase PF00719.19 CBY14392.1 - 3.1e-56 189.6 1.4 4.1e-56 189.2 1.4 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Utp21 PF04192.12 CBY14393.1 - 3.1e-24 85.8 0.0 5.6e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CBY14393.1 - 1.2e-18 67.2 2.1 0.00041 20.6 0.0 6.5 2 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY14393.1 - 2.5e-18 66.1 7.7 5.3e-08 33.4 0.9 7.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 CBY14393.1 - 5.4e-05 22.0 0.2 0.21 10.2 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CBY14393.1 - 9.1e-05 21.4 3.3 0.034 12.9 0.8 3.5 2 1 1 3 3 3 1 Nup133 N terminal like eIF2A PF08662.11 CBY14393.1 - 0.00077 19.4 1.5 0.79 9.6 0.1 3.3 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY14393.1 - 0.0011 18.4 0.8 0.01 15.2 0.3 2.7 3 1 0 3 3 3 1 WD40-like domain PHTB1_N PF14727.6 CBY14393.1 - 0.02 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 PTHB1 N-terminus PQQ PF01011.21 CBY14393.1 - 0.032 14.1 0.0 30 4.8 0.0 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat Ge1_WD40 PF16529.5 CBY14393.1 - 0.041 12.8 0.7 4 6.3 0.0 3.7 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4221 PF13970.6 CBY14393.1 - 0.099 12.2 0.1 0.56 9.7 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4221) EMP70 PF02990.16 CBY14394.1 - 8.9e-204 678.0 11.3 1.2e-203 677.5 11.3 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Clathrin PF00637.20 CBY14395.1 - 0.025 14.5 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Kinesin PF00225.23 CBY14396.1 - 3.1e-85 286.0 0.0 3.1e-85 286.0 0.0 2.6 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY14396.1 - 1.3e-21 77.1 0.0 4.8e-19 68.8 0.0 3.2 2 0 0 2 2 2 2 Microtubule binding CdvA PF18822.1 CBY14396.1 - 0.0054 16.6 5.6 0.0054 16.6 5.6 9.0 7 3 5 12 12 12 1 CdvA-like coiled-coil domain DUF3287 PF11690.8 CBY14396.1 - 0.57 9.9 3.6 3.9 7.2 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) PilJ PF13675.6 CBY14396.1 - 5.4 7.1 11.5 7 6.7 1.4 4.3 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term FCH PF00611.23 CBY14397.1 - 5.9e-08 32.9 0.0 2.7e-07 30.7 0.0 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CBY14397.1 - 2.8e-07 30.0 0.2 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CBY14397.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CBY14397.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain DUF725 PF05267.12 CBY14397.1 - 0.064 13.2 12.8 0.36 10.8 0.7 4.7 3 1 0 4 4 4 0 Protein of unknown function (DUF725) Exonuc_VII_L PF02601.15 CBY14397.1 - 2.1 7.9 15.6 3.9 6.9 3.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit EI24 PF07264.11 CBY14398.1 - 3.1e-19 69.9 11.1 4.3e-19 69.4 11.1 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Rad51 PF08423.11 CBY14399.1 - 2.6e-113 377.5 0.1 4.1e-113 376.9 0.1 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBY14399.1 - 3.9e-10 39.6 0.2 5.9e-10 39.1 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBY14399.1 - 4.3e-07 29.7 0.0 6.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBY14399.1 - 1.7e-05 24.3 0.8 7.8e-05 22.1 0.8 2.1 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 CBY14399.1 - 0.0035 17.9 0.0 0.0069 17.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 CBY14399.1 - 0.073 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF3173 PF11372.8 CBY14399.1 - 0.096 12.6 0.1 0.26 11.2 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3173) Pkinase PF00069.25 CBY14400.1 - 3.5e-76 256.0 0.0 4e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14400.1 - 1.6e-35 122.6 0.0 2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY14400.1 - 7.1e-06 25.2 0.0 6.9e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY14400.1 - 8.4e-06 25.3 0.0 3.1e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBY14400.1 - 0.0015 18.5 0.1 0.0057 16.6 0.1 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY14400.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 CBY14401.1 - 6.3e-30 104.4 0.0 1e-29 103.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14401.1 - 3.3e-25 88.9 0.0 6e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY14401.1 - 0.021 13.6 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CBY14403.1 - 6.4e-07 29.0 0.1 7.2e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14403.1 - 2.8e-05 23.5 0.0 3.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY14405.1 - 1.7e-05 24.3 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Mu-like_Pro PF10123.9 CBY14406.1 - 0.091 12.3 5.9 0.13 11.8 5.9 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein Macoilin PF09726.9 CBY14406.1 - 0.12 10.9 15.4 0.16 10.5 15.4 1.1 1 0 0 1 1 1 0 Macoilin family TPR_MLP1_2 PF07926.12 CBY14406.1 - 0.13 12.3 19.0 0.65 10.1 10.6 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 CBY14406.1 - 0.16 9.9 7.4 0.17 9.7 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Striatin PF08232.12 CBY14406.1 - 1.1 9.8 16.8 3.2 8.3 16.8 1.7 1 0 0 1 1 1 0 Striatin family RBD-FIP PF09457.10 CBY14406.1 - 1.1 9.2 5.4 0.28 11.2 0.5 2.4 2 0 0 2 2 2 0 FIP domain THOC7 PF05615.13 CBY14406.1 - 1.3 9.3 17.9 0.63 10.3 7.0 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 Exonuc_VII_L PF02601.15 CBY14406.1 - 2.7 7.5 10.4 3.5 7.1 10.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NYD-SP28_assoc PF14775.6 CBY14406.1 - 6.1 7.0 14.4 0.42 10.7 2.2 3.0 3 1 0 3 3 3 0 Sperm tail C-terminal domain Dfp1_Him1_M PF08630.10 CBY14406.1 - 7.1 6.9 8.8 2.7 8.2 6.0 1.7 1 1 1 2 2 2 0 Dfp1/Him1, central region DUF1664 PF07889.12 CBY14406.1 - 7.5 6.6 10.2 0.86 9.7 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 CBY14406.1 - 7.9 6.8 21.9 0.76 10.1 6.2 3.4 1 1 2 3 3 3 0 ABC transporter C-terminal domain YscO PF07321.12 CBY14409.1 - 1.1 9.2 12.0 0.083 12.8 6.9 1.7 2 0 0 2 2 2 0 Type III secretion protein YscO RbsD_FucU PF05025.13 CBY14409.1 - 2.5 8.5 4.8 0.88 10.0 1.4 1.9 2 0 0 2 2 2 0 RbsD / FucU transport protein family TPR_MLP1_2 PF07926.12 CBY14409.1 - 5.8 7.0 25.4 1.9 8.6 18.0 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CREPT PF16566.5 CBY14409.1 - 9.3 6.4 12.2 0.26 11.4 5.5 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Hema_stalk PF08720.10 CBY14410.1 - 0.018 14.7 0.3 0.031 14.0 0.3 1.4 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk Transglycosylas PF06737.14 CBY14410.1 - 0.093 13.4 0.5 0.16 12.6 0.5 1.4 1 0 0 1 1 1 0 Transglycosylase-like domain TSP_1 PF00090.19 CBY14412.1 - 7.7e-05 22.8 12.7 7.7e-05 22.8 12.7 4.4 5 1 0 5 5 5 1 Thrombospondin type 1 domain Pkinase PF00069.25 CBY14413.1 - 1.4e-10 41.0 1.8 2.7e-10 40.1 1.8 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14413.1 - 5e-05 22.7 0.1 7.8e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DHC_N1 PF08385.12 CBY14414.1 - 5.6e-140 467.6 0.5 5.6e-140 467.6 0.5 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CBY14414.1 - 8.2e-111 370.9 9.1 1.4e-73 248.3 1.2 3.3 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 DUF2312 PF10073.9 CBY14414.1 - 0.031 13.9 0.0 0.21 11.3 0.0 2.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) ERK-JNK_inhib PF15002.6 CBY14414.1 - 0.037 13.7 0.3 0.2 11.3 0.1 2.4 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor PTS-HPr PF00381.19 CBY14414.1 - 0.049 13.9 0.3 0.18 12.1 0.3 2.0 1 0 0 1 1 1 0 PTS HPr component phosphorylation site ADD_DNMT3 PF17980.1 CBY14414.1 - 0.095 12.7 0.0 0.37 10.8 0.0 2.1 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 zf-C3HC4_3 PF13920.6 CBY14418.1 - 3.7e-09 36.3 9.4 3.7e-09 36.3 9.4 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY14418.1 - 9e-07 28.8 11.7 9e-07 28.8 11.7 2.9 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY14418.1 - 3.1e-05 23.8 11.0 3.1e-05 23.8 11.0 3.0 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY14418.1 - 8.2e-05 22.4 11.9 8.2e-05 22.4 11.9 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY14418.1 - 0.00017 21.9 11.7 0.00017 21.9 11.7 2.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY14418.1 - 0.00069 19.4 12.1 0.00069 19.4 12.1 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY14418.1 - 0.0024 17.9 4.8 0.0024 17.9 4.8 3.5 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_4 PF14570.6 CBY14418.1 - 0.0042 16.9 8.7 0.0042 16.9 8.7 3.3 3 2 0 3 3 3 1 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 CBY14418.1 - 0.017 15.0 0.4 0.017 15.0 0.4 2.4 3 0 0 3 3 3 0 Rad50 zinc hook motif AvrB_AvrC PF05394.11 CBY14418.1 - 0.038 13.2 1.1 0.051 12.8 1.1 1.1 1 0 0 1 1 1 0 Avirulence protein Astacin PF01400.24 CBY14419.1 - 1.7e-34 119.1 0.2 2.3e-34 118.7 0.2 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY14419.1 - 0.0023 18.1 5.5 0.0052 17.0 5.5 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 CBY14421.1 - 1.9e-42 143.2 128.1 5.6e-11 42.5 5.9 9.3 9 1 0 9 9 9 8 Thrombospondin type 1 domain zf-CCCH PF00642.24 CBY14421.1 - 0.11 12.4 11.1 3 7.9 0.6 5.7 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4396 PF14342.6 CBY14422.1 - 0.045 14.1 0.4 0.045 14.1 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Kelch_6 PF13964.6 CBY14423.1 - 2.3e-08 34.0 8.2 0.037 14.3 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 CBY14423.1 - 1.9e-07 30.9 20.8 0.74 9.9 0.0 7.8 9 0 0 9 9 9 5 Kelch motif Kelch_2 PF07646.15 CBY14423.1 - 6e-06 26.0 14.3 0.2 11.7 0.0 7.4 8 0 0 8 8 8 2 Kelch motif Kelch_1 PF01344.25 CBY14423.1 - 8.6e-06 25.3 10.6 0.43 10.2 0.0 7.0 7 0 0 7 7 7 2 Kelch motif Kelch_4 PF13418.6 CBY14423.1 - 0.054 13.5 21.8 5.9 7.0 0.0 7.1 8 0 0 8 8 8 0 Galactose oxidase, central domain TSP_1 PF00090.19 CBY14425.1 - 2.3e-14 53.3 26.9 5.1e-08 33.0 8.0 2.2 2 0 0 2 2 2 2 Thrombospondin type 1 domain HMG_box PF00505.19 CBY14427.1 - 9.1e-09 35.6 28.3 1.4e-07 31.9 5.9 4.0 3 2 1 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY14427.1 - 0.012 16.2 5.6 0.012 16.2 5.6 4.1 3 2 2 5 5 5 0 HMG-box domain HMG_box PF00505.19 CBY14428.1 - 1.1e-08 35.4 4.1 2.1e-08 34.5 2.7 2.2 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY14428.1 - 4.1e-08 33.7 6.4 7.5e-08 32.9 3.6 2.3 2 0 0 2 2 2 1 HMG-box domain MAS20 PF02064.15 CBY14428.1 - 0.3 11.2 2.6 0.47 10.6 2.6 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor ArgoL2 PF16488.5 CBY14429.1 - 0.035 14.5 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 Argonaute linker 2 domain Zona_pellucida PF00100.23 CBY14430.1 - 2.7e-26 92.9 0.4 3.3e-26 92.6 0.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Insulin_TMD PF17870.1 CBY14430.1 - 0.065 13.3 3.4 0.12 12.5 3.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 CBY14430.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) PTEN_C2 PF10409.9 CBY14430.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein DUF4083 PF13314.6 CBY14430.1 - 0.28 11.2 2.8 0.51 10.3 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF4006 PF13179.6 CBY14430.1 - 0.32 10.9 1.4 0.61 10.0 1.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Rhodanese PF00581.20 CBY14432.1 - 3.5e-09 37.1 0.1 3.9e-09 37.0 0.1 1.0 1 0 0 1 1 1 1 Rhodanese-like domain Vps4_C PF09336.10 CBY14432.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Peptidase_M28 PF04389.17 CBY14433.1 - 4.6e-39 134.2 0.0 5.8e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 CLP_protease PF00574.23 CBY14435.1 - 6.3e-69 231.5 0.0 8.2e-69 231.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease zf-ANAPC11 PF12861.7 CBY14436.1 - 1.8e-26 92.0 9.9 2.3e-26 91.7 9.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CBY14436.1 - 9.9e-18 64.2 11.1 1.5e-17 63.6 11.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBY14436.1 - 9e-07 29.1 13.4 1.6e-05 25.1 13.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY14436.1 - 0.0026 17.6 11.8 0.012 15.4 11.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY14436.1 - 0.0043 17.0 11.5 0.028 14.4 11.7 2.0 1 1 1 2 2 2 1 zinc-RING finger domain Rad50_zn_hook PF04423.14 CBY14436.1 - 0.037 13.9 0.3 0.037 13.9 0.3 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif FANCL_C PF11793.8 CBY14436.1 - 0.055 13.6 10.6 0.16 12.2 10.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CBY14436.1 - 0.078 13.0 7.2 0.12 12.4 5.5 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.8 CBY14436.1 - 0.12 12.2 5.1 0.21 11.4 5.1 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 CBY14436.1 - 0.27 11.0 9.2 2.8 7.8 6.1 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 CBY14436.1 - 0.84 9.7 7.8 9.1 6.4 2.3 2.6 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_3 PF13920.6 CBY14436.1 - 0.87 9.5 12.3 30 4.6 0.2 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY14436.1 - 0.95 9.4 18.5 0.62 9.9 11.7 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 CBY14436.1 - 1.5 9.0 13.2 0.14 12.3 4.7 2.4 2 1 0 2 2 2 0 RING-variant domain Prok-RING_1 PF14446.6 CBY14436.1 - 3 7.9 13.9 49 4.0 0.1 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_11 PF17123.5 CBY14436.1 - 3.6 7.4 12.5 42 4.0 12.5 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBY14436.1 - 4.3 7.6 9.4 0.13 12.4 2.5 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.6 CBY14436.1 - 5.8 7.2 12.3 75 3.7 12.0 2.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain NAPRTase PF04095.16 CBY14437.1 - 2.1e-57 194.5 0.2 2.7e-57 194.2 0.2 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 CBY14437.1 - 3e-23 82.1 0.4 4.9e-20 71.8 0.4 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5598) L_lac_phage_MSP PF06488.11 CBY14437.1 - 0.021 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein SET PF00856.28 CBY14440.1 - 6.2e-09 36.5 0.0 7.8e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 SET domain TetR_C_30 PF17939.1 CBY14440.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-HIT PF04438.16 CBY14440.1 - 0.17 11.8 1.0 0.35 10.8 1.0 1.5 1 0 0 1 1 1 0 HIT zinc finger Pkinase PF00069.25 CBY14441.1 - 1.8e-05 24.2 0.0 4.8e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14441.1 - 5.9e-05 22.5 0.0 0.00013 21.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase zf-RanBP PF00641.18 CBY14445.1 - 7.5e-07 28.4 18.0 0.00064 19.0 5.0 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 CBY14445.1 - 2.7e-06 26.6 15.6 0.0073 15.7 5.2 3.5 2 1 1 3 3 3 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C3HC4_3 PF13920.6 CBY14445.1 - 5.1 7.1 9.4 9.9 6.1 1.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nucleoporin_FG PF13634.6 CBY14445.1 - 7.1 7.6 186.2 0.18 12.7 33.8 8.3 2 1 6 8 8 8 0 Nucleoporin FG repeat region Ly49 PF08391.10 CBY14446.1 - 8.8 6.7 7.6 2.9 8.3 0.6 2.1 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region PKcGMP_CC PF16808.5 CBY14447.1 - 0.00045 20.0 16.7 0.0029 17.4 1.4 3.5 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Sigma70_r4_2 PF08281.12 CBY14447.1 - 0.0036 17.0 0.9 0.61 9.8 0.0 3.9 4 0 0 4 4 4 1 Sigma-70, region 4 DUF1664 PF07889.12 CBY14447.1 - 1.5 8.9 16.3 10 6.1 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RGS PF00615.19 CBY14448.1 - 2e-12 47.4 1.5 4.3e-08 33.4 0.4 2.9 3 0 0 3 3 3 2 Regulator of G protein signaling domain ACAS_N PF16177.5 CBY14448.1 - 0.15 12.0 1.0 5.4 7.0 0.1 2.7 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus DUF2407 PF10302.9 CBY14449.1 - 0.19 12.3 1.0 0.2 12.2 1.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RcpB PF16971.5 CBY14450.1 - 0.002 18.0 0.7 0.0031 17.4 0.7 1.2 1 0 0 1 1 1 1 Rough colony protein B, tight adherence - tad - subunit GTP-bdg_M PF16360.5 CBY14450.1 - 0.092 13.4 2.3 0.21 12.2 2.3 1.6 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region TMPIT PF07851.13 CBY14450.1 - 0.92 8.7 4.6 1.2 8.3 4.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein HTH_Tnp_Tc5 PF03221.16 CBY14451.1 - 1.2e-10 41.3 15.2 0.00026 21.0 0.0 6.3 7 0 0 7 7 7 3 Tc5 transposase DNA-binding domain Creb_binding PF09030.10 CBY14451.1 - 0.038 14.7 0.1 0.12 13.1 0.1 1.8 1 0 0 1 1 1 0 Creb binding Nab2p_Zf1 PF18260.1 CBY14451.1 - 0.2 11.6 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 GST_N PF02798.20 CBY14452.1 - 7.2e-08 32.7 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBY14452.1 - 0.015 15.4 0.0 0.033 14.4 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBY14452.1 - 0.023 15.1 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 CBY14452.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein T-box PF00907.22 CBY14453.1 - 9.7e-83 276.9 0.6 1.2e-82 276.7 0.6 1.1 1 0 0 1 1 1 1 T-box TUDOR PF00567.24 CBY14454.1 - 2.9e-12 46.7 0.0 8.6e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Tudor domain OST-HTH PF12872.7 CBY14454.1 - 9.3e-06 25.4 0.2 0.00073 19.3 0.0 2.7 2 0 0 2 2 2 1 OST-HTH/LOTUS domain TcpS PF17456.2 CBY14454.1 - 0.025 14.6 1.4 0.76 9.8 0.1 2.6 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S DNA_pol_B_2 PF03175.13 CBY14455.1 - 8.5e-11 41.4 10.9 9.9e-07 28.0 5.1 2.5 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DUF1979 PF09322.10 CBY14456.1 - 0.19 11.6 0.4 0.39 10.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) ABC_tran PF00005.27 CBY14458.1 - 5.6e-26 91.7 0.0 8.2e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBY14458.1 - 3.6e-08 33.1 1.2 2.2e-06 27.3 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DEAD PF00270.29 CBY14458.1 - 0.00076 19.3 0.7 0.0028 17.4 0.7 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY14458.1 - 0.0013 19.0 0.3 0.0096 16.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 CBY14458.1 - 0.0018 18.4 1.0 0.0049 17.0 0.1 2.0 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 CBY14458.1 - 0.016 15.0 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CBY14458.1 - 0.022 14.5 0.1 0.039 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 CBY14458.1 - 0.029 13.8 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 CBY14458.1 - 0.041 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 CBY14458.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 CBY14458.1 - 0.084 11.8 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 CBY14458.1 - 0.11 12.6 0.2 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase WHEP-TRS PF00458.20 CBY14459.1 - 1.4e-18 66.8 27.6 2.5e-10 40.4 2.5 5.6 5 1 0 5 5 5 3 WHEP-TRS domain PPDFL PF15060.6 CBY14459.1 - 0.043 14.3 0.7 0.14 12.7 0.1 2.2 2 0 0 2 2 2 0 Differentiation and proliferation regulator DUF4682 PF15733.5 CBY14459.1 - 0.12 13.0 4.5 0.85 10.2 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4682) DUF16 PF01519.16 CBY14460.1 - 0.0043 17.5 5.5 0.0076 16.7 5.0 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF16 CHDCT2 PF08074.11 CBY14460.1 - 0.0047 17.1 1.7 0.0072 16.5 1.7 1.3 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain Troponin PF00992.20 CBY14460.1 - 0.0066 16.7 0.8 0.012 15.9 0.8 1.3 1 0 0 1 1 1 1 Troponin SNARE PF05739.19 CBY14460.1 - 0.0074 16.3 0.4 0.019 15.0 0.4 1.7 1 0 0 1 1 1 1 SNARE domain UPF0242 PF06785.11 CBY14460.1 - 0.07 13.2 5.8 0.092 12.8 5.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Citrus_P18 PF05520.11 CBY14460.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Cor1 PF04803.12 CBY14460.1 - 1.3 9.2 12.8 0.19 11.9 8.6 1.7 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region WD40 PF00400.32 CBY14461.1 - 9.4e-17 61.1 6.0 4.1e-10 40.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY14461.1 - 9.6e-14 51.5 1.1 2.1e-07 31.1 0.3 3.6 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY14461.1 - 0.098 12.0 0.0 0.93 8.8 0.0 2.1 2 1 0 2 2 2 0 WD40-like domain eIF2A PF08662.11 CBY14461.1 - 0.12 12.2 0.2 1.4 8.8 0.2 2.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A EF-hand_6 PF13405.6 CBY14462.1 - 0.042 13.8 1.6 1 9.4 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 CBY14462.1 - 0.051 14.0 0.4 0.27 11.7 0.3 1.9 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 CBY14462.1 - 0.12 12.0 3.2 0.42 10.3 0.0 2.7 3 1 0 3 3 3 0 EF hand RT_RNaseH_2 PF17919.1 CBY14463.1 - 1e-10 41.5 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY14463.1 - 2.1e-06 27.4 0.0 6.1e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CBY14463.1 - 7e-06 26.6 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 CBY14463.1 - 0.017 15.4 0.1 0.057 13.7 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF1758 PF05585.12 CBY14463.1 - 0.043 13.6 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_thumb PF06817.14 CBY14463.1 - 0.066 13.1 0.2 0.47 10.3 0.2 2.2 1 1 0 1 1 1 0 Reverse transcriptase thumb domain An_peroxidase PF03098.15 CBY14464.1 - 9.9e-47 159.7 0.0 1.4e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Ammonium_transp PF00909.21 CBY14465.1 - 7.1e-90 301.6 19.9 1.1e-88 297.7 19.9 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family ThrE PF06738.12 CBY14465.1 - 0.11 11.8 0.0 0.11 11.8 0.0 3.0 3 1 0 3 3 3 0 Putative threonine/serine exporter DUF2583 PF10762.9 CBY14465.1 - 0.61 10.5 6.1 2.7 8.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) Neurensin PF14927.6 CBY14465.1 - 1.5 8.5 5.4 3.5 7.3 0.2 3.1 1 1 1 2 2 2 0 Neurensin Trypsin PF00089.26 CBY14466.1 - 2e-45 155.3 0.8 2e-45 155.3 0.8 3.8 4 0 0 4 4 4 1 Trypsin cEGF PF12662.7 CBY14466.1 - 8.6e-08 32.0 0.4 3.6e-07 30.0 0.4 2.2 1 0 0 1 1 1 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY14466.1 - 0.00046 20.4 6.0 0.00046 20.4 6.0 3.4 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site LepB_GAP_N PF18172.1 CBY14466.1 - 0.032 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain EGF_3 PF12947.7 CBY14466.1 - 3.5 7.9 13.0 2 8.7 1.5 3.6 2 0 0 2 2 2 0 EGF domain ABC_tran PF00005.27 CBY14467.1 - 1.3e-13 51.7 0.5 1.8e-13 51.2 0.5 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CBY14467.1 - 2.9e-05 24.0 0.8 6e-05 23.0 0.8 1.7 1 1 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 CBY14467.1 - 0.00025 21.1 1.1 0.0006 19.9 1.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBY14467.1 - 0.00059 19.9 0.3 0.0034 17.5 0.3 2.2 1 1 0 1 1 1 1 Dynamin family AAA_22 PF13401.6 CBY14467.1 - 0.0006 20.1 0.4 0.0057 16.9 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY14467.1 - 0.0019 18.6 0.0 0.0024 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 CBY14467.1 - 0.0027 17.9 0.5 0.0049 17.0 0.5 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 CBY14467.1 - 0.003 17.3 0.3 0.0062 16.3 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 CBY14467.1 - 0.0067 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Septin PF00735.18 CBY14467.1 - 0.0099 15.2 0.5 0.015 14.6 0.5 1.5 1 1 0 1 1 1 1 Septin AAA_28 PF13521.6 CBY14467.1 - 0.012 15.8 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBY14467.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 CBY14467.1 - 0.02 14.6 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 CBY14467.1 - 0.02 13.8 0.4 0.028 13.4 0.3 1.3 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CBY14467.1 - 0.026 14.2 0.1 0.046 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 CBY14467.1 - 0.035 14.0 0.2 0.08 12.8 0.1 1.6 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 CBY14467.1 - 0.046 13.6 0.1 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 CBY14467.1 - 0.049 12.8 0.8 0.079 12.1 0.4 1.7 1 1 1 2 2 2 0 NB-ARC domain T2SSE PF00437.20 CBY14467.1 - 0.059 12.4 0.1 0.074 12.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 CBY14467.1 - 0.067 13.7 0.1 0.098 13.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain GBP PF02263.19 CBY14467.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain cobW PF02492.19 CBY14467.1 - 0.083 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CBY14467.1 - 0.091 12.5 1.6 0.092 12.5 0.5 1.7 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 CBY14467.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBY14467.1 - 0.4 11.2 0.3 0.4 11.2 0.3 2.3 2 1 1 3 3 3 0 AAA domain ABC2_membrane PF01061.24 CBY14468.1 - 4.1e-36 124.4 23.4 5.1e-36 124.1 23.4 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CBY14468.1 - 0.55 9.3 26.1 1.9 7.5 25.9 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3392 PF11872.8 CBY14468.1 - 0.84 9.9 4.5 0.76 10.1 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Kelch_6 PF13964.6 CBY14471.1 - 0.013 15.7 0.2 1.2 9.5 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY14471.1 - 0.022 14.8 0.3 7.2 6.7 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 CBY14471.1 - 0.071 13.1 1.2 0.87 9.7 0.0 3.1 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 CBY14471.1 - 0.076 13.0 0.7 3.4 7.8 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY14472.1 - 0.00015 21.6 0.5 0.92 9.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY14472.1 - 0.00037 20.7 0.2 0.75 10.2 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY14472.1 - 0.0064 16.5 0.3 0.63 10.1 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY14472.1 - 0.02 14.9 3.8 0.16 12.0 0.0 3.5 4 0 0 4 4 4 0 Kelch motif STPPase_N PF16891.5 CBY14473.1 - 2.5e-15 56.6 0.3 4.2e-15 55.9 0.3 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CBY14473.1 - 2.6e-08 34.6 0.0 3.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RTP801_C PF07809.11 CBY14475.1 - 0.078 12.9 0.5 0.12 12.3 0.5 1.3 1 1 0 1 1 1 0 RTP801 C-terminal region DsrC PF04358.13 CBY14476.1 - 0.036 14.6 0.6 0.5 10.9 0.1 2.4 2 0 0 2 2 2 0 DsrC like protein 7tm_2 PF00002.24 CBY14477.1 - 8.5e-22 77.6 0.3 1.1e-21 77.2 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) AltA1 PF16541.5 CBY14478.1 - 0.25 12.2 6.1 0.17 12.7 0.5 2.2 1 1 1 2 2 2 0 Alternaria alternata allergen 1 Pkinase PF00069.25 CBY14479.1 - 6.1e-50 170.0 0.0 1.6e-49 168.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14479.1 - 1.9e-22 79.8 0.0 3.1e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY14479.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBY14479.1 - 0.046 13.3 0.2 6.9 6.2 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBY14479.1 - 0.051 12.3 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBY14479.1 - 0.054 12.8 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Collagen PF01391.18 CBY14480.1 - 1e-32 111.7 121.2 1.8e-10 40.4 24.4 3.1 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) DUF2408 PF10303.9 CBY14481.1 - 0.037 14.6 2.1 0.058 14.0 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) ID PF18543.1 CBY14481.1 - 0.04 13.9 2.0 4.9 7.3 0.2 2.5 2 0 0 2 2 2 0 Intracellular delivery domain Lys PF00062.20 CBY14481.1 - 0.044 14.0 0.9 0.064 13.5 0.9 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family ABC2_membrane_3 PF12698.7 CBY14481.1 - 0.17 11.0 0.7 0.18 10.9 0.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3504 PF12012.8 CBY14482.1 - 3.1e-22 79.2 0.0 8.8e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) ARID PF01388.21 CBY14483.1 - 9.7e-21 74.3 0.0 2.5e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF5585 PF17823.1 CBY14483.1 - 0.17 10.8 17.2 0.36 9.8 17.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Atg8 PF02991.16 CBY14484.1 - 4.3e-34 116.8 0.5 6.9e-34 116.2 0.5 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBY14484.1 - 3.8e-05 24.0 0.0 5.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.12 CBY14484.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 KDZ PF18758.1 CBY14486.1 - 0.067 12.8 2.8 0.07 12.7 2.8 1.4 1 1 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Neur_chan_LBD PF02931.23 CBY14487.1 - 1e-40 139.5 0.1 1e-40 139.5 0.1 1.9 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY14487.1 - 4.4e-32 112.0 0.8 9.2e-32 111.0 0.8 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Importin_rep_6 PF18829.1 CBY14487.1 - 0.093 12.9 1.4 0.2 11.8 1.4 1.6 1 0 0 1 1 1 0 Importin repeat 6 DivIC PF04977.15 CBY14487.1 - 0.13 12.0 1.8 0.34 10.7 1.8 1.7 1 0 0 1 1 1 0 Septum formation initiator MgtE PF01769.16 CBY14487.1 - 0.5 10.8 5.0 0.53 10.7 1.3 2.5 3 0 0 3 3 3 0 Divalent cation transporter Orf78 PF06024.12 CBY14487.1 - 2.7 8.3 5.6 24 5.3 5.6 2.4 1 1 0 1 1 1 0 Orf78 (ac78) Peptidase_S49_N PF08496.10 CBY14487.1 - 4.2 7.4 6.6 2.6 8.1 1.0 2.2 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Pkinase PF00069.25 CBY14488.1 - 7e-32 110.8 0.0 8.7e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14488.1 - 2.7e-20 72.7 0.0 3.1e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY14488.1 - 4.4e-10 39.3 0.0 4.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY14488.1 - 0.00014 20.7 0.0 0.0002 20.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY14488.1 - 0.00056 19.9 0.0 0.00085 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C4 PF00105.18 CBY14489.1 - 6e-10 39.4 15.1 1.7e-09 37.9 15.1 1.8 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY14489.1 - 8.8e-06 25.4 0.2 2.1e-05 24.2 0.2 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TRAP_alpha PF03896.16 CBY14490.1 - 0.014 14.6 0.3 0.02 14.1 0.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sof1 PF04158.14 CBY14491.1 - 0.087 13.1 0.1 0.17 12.2 0.0 1.5 2 0 0 2 2 2 0 Sof1-like domain DUF5365 PF17326.2 CBY14492.1 - 0.082 13.3 0.0 0.18 12.2 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5365) Ammonium_transp PF00909.21 CBY14493.1 - 3e-17 62.4 9.2 3.6e-17 62.1 9.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Saf_2TM PF18303.1 CBY14493.1 - 0.036 13.6 0.1 0.48 10.0 0.0 2.5 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain DUF4795 PF16043.5 CBY14494.1 - 0.0082 15.8 6.0 0.013 15.2 6.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Ion_trans PF00520.31 CBY14494.1 - 0.017 14.4 0.2 0.024 13.9 0.2 1.2 1 0 0 1 1 1 0 Ion transport protein DUF4407 PF14362.6 CBY14494.1 - 0.066 12.5 3.8 0.09 12.1 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IGR PF09597.10 CBY14494.1 - 0.11 12.6 1.0 5.3 7.2 0.0 3.2 3 0 0 3 3 3 0 IGR protein motif OmpH PF03938.14 CBY14494.1 - 0.44 10.9 9.2 0.79 10.1 9.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 CBY14494.1 - 0.74 10.3 8.0 57 4.3 8.0 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 LMBR1 PF04791.16 CBY14494.1 - 1.4 7.7 3.2 1.7 7.4 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Troponin PF00992.20 CBY14494.1 - 1.6 9.0 10.6 0.085 13.2 3.0 2.1 2 0 0 2 2 2 0 Troponin DUF4164 PF13747.6 CBY14494.1 - 2.9 8.2 6.9 2.5 8.4 0.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF1690 PF07956.11 CBY14494.1 - 2.9 8.3 8.6 2.5 8.5 6.3 2.1 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) Arf PF00025.21 CBY14495.1 - 8.7e-64 214.2 0.1 1e-63 213.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBY14495.1 - 1.2e-15 57.5 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY14495.1 - 1.5e-15 57.4 0.1 2.2e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CBY14495.1 - 4.6e-14 52.3 1.9 1.8e-09 37.2 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY14495.1 - 9.7e-10 38.2 0.1 1.3e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBY14495.1 - 2.7e-09 36.7 0.0 3.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY14495.1 - 0.0008 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBY14495.1 - 0.0033 16.8 0.3 0.0061 15.9 0.1 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 CBY14495.1 - 0.033 14.4 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 PHD_like PF12910.7 CBY14495.1 - 0.039 14.0 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system AAA PF00004.29 CBY14496.1 - 1.5e-09 38.4 0.1 1.1e-07 32.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 CBY14496.1 - 0.00038 20.0 0.3 0.00082 19.0 0.3 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Rad17 PF03215.15 CBY14496.1 - 0.0098 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CBY14496.1 - 0.01 15.6 0.1 0.045 13.5 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBY14496.1 - 0.017 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY14496.1 - 0.047 14.1 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Collagen PF01391.18 CBY14496.1 - 2.6 7.9 26.2 0.019 14.7 10.7 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Band_7 PF01145.25 CBY14498.1 - 1.6e-14 54.3 0.0 1.7e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family CdiI_4 PF18624.1 CBY14498.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 CDI immunity protein Flot PF15975.5 CBY14499.1 - 1.2e-08 35.1 13.2 1.6e-08 34.8 5.5 2.8 2 1 1 3 3 3 2 Flotillin ATP_bind_2 PF03668.15 CBY14499.1 - 0.04 13.2 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family Band_7 PF01145.25 CBY14500.1 - 2.1e-16 60.4 0.0 6e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 SPFH domain / Band 7 family Flot PF15975.5 CBY14500.1 - 7.4e-11 42.3 8.0 4.6e-07 30.0 6.3 5.0 4 2 1 5 5 5 3 Flotillin DUF244 PF03112.14 CBY14500.1 - 0.22 11.4 1.1 0.36 10.7 1.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Band_7 PF01145.25 CBY14501.1 - 1.4e-14 54.5 0.0 1.6e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family CXCL17 PF15211.6 CBY14501.1 - 0.14 12.9 0.3 0.2 12.4 0.3 1.2 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 Band_7 PF01145.25 CBY14502.1 - 1.8e-24 86.7 0.3 5e-24 85.3 0.0 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 CBY14502.1 - 2.9e-05 24.2 9.1 2.9e-05 24.2 9.1 3.5 2 1 0 2 2 2 1 Flotillin Viral_P18 PF04521.13 CBY14502.1 - 0.00066 19.5 1.6 0.0013 18.5 0.1 2.2 2 0 0 2 2 2 1 ssRNA positive strand viral 18kD cysteine rich protein CSD2 PF17876.1 CBY14502.1 - 0.047 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Cold shock domain AAA PF00004.29 CBY14503.1 - 1.6e-42 145.0 0.0 6.3e-42 143.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY14503.1 - 2.6e-09 36.8 0.2 5e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CBY14503.1 - 3.8e-09 36.4 0.1 8.7e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CBY14503.1 - 5.2e-06 26.7 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBY14503.1 - 3.7e-05 24.0 0.9 0.0025 18.1 0.2 2.7 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 CBY14503.1 - 4.7e-05 22.7 0.0 8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CBY14503.1 - 7.2e-05 22.8 0.4 0.001 19.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBY14503.1 - 0.0002 21.2 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBY14503.1 - 0.00025 21.4 0.1 0.0029 18.0 0.0 2.3 2 1 1 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.17 CBY14503.1 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CBY14503.1 - 0.0039 17.4 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBY14503.1 - 0.0043 17.4 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 CBY14503.1 - 0.0052 17.3 0.0 0.014 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBY14503.1 - 0.0055 16.5 1.4 1 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 CBY14503.1 - 0.0058 16.2 0.1 0.017 14.8 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 CBY14503.1 - 0.0068 16.7 0.1 0.014 15.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 CBY14503.1 - 0.0088 15.3 0.1 0.5 9.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 CBY14503.1 - 0.012 15.6 0.1 0.083 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 CBY14503.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CBY14503.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3363 PF11843.8 CBY14503.1 - 0.019 13.9 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) AAA_24 PF13479.6 CBY14503.1 - 0.031 14.0 0.1 0.1 12.3 0.1 1.9 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 CBY14503.1 - 0.036 13.5 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 CBY14503.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBY14503.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CBY14503.1 - 0.059 12.7 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 CBY14503.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CBY14503.1 - 0.087 12.4 0.3 0.31 10.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 CBY14503.1 - 0.092 13.3 0.1 0.41 11.2 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 CBY14503.1 - 0.092 12.4 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CBY14503.1 - 0.098 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 CBY14503.1 - 0.11 12.3 1.9 1.8 8.5 0.0 2.9 2 2 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CBY14503.1 - 0.14 11.8 0.2 0.58 9.8 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain BORCS7 PF16088.5 CBY14504.1 - 0.00032 20.9 0.1 0.00038 20.7 0.1 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 tRNA_int_endo PF01974.17 CBY14506.1 - 1.3e-10 41.2 0.1 2.6e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ank_2 PF12796.7 CBY14507.1 - 2.1e-31 108.3 0.8 1.6e-12 47.8 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY14507.1 - 2.2e-30 104.6 4.8 1.5e-13 51.0 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY14507.1 - 1.2e-20 73.3 1.8 4.8e-05 23.6 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY14507.1 - 5e-20 69.5 1.8 0.0001 22.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CBY14507.1 - 1.1e-18 66.8 1.5 7.8e-05 22.9 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Connexin PF00029.19 CBY14509.1 - 2.8e-64 217.1 7.3 4e-64 216.6 7.3 1.2 1 0 0 1 1 1 1 Connexin JTB PF05439.12 CBY14509.1 - 0.023 14.7 4.4 0.18 11.9 0.8 2.6 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) Ac76 PF05814.11 CBY14509.1 - 0.025 14.6 0.1 0.025 14.6 0.1 2.7 4 0 0 4 4 4 0 Orf76 (Ac76) TspO_MBR PF03073.15 CBY14509.1 - 5.4 7.1 9.6 6.5 6.8 0.1 3.5 4 0 0 4 4 4 0 TspO/MBR family G-gamma PF00631.22 CBY14513.1 - 0.0002 21.3 0.0 0.00047 20.1 0.0 1.7 1 1 0 1 1 1 1 GGL domain Kelch_2 PF07646.15 CBY14514.1 - 0.0026 17.7 0.6 0.67 10.0 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY14514.1 - 0.16 12.0 5.0 1.9 8.6 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY14514.1 - 0.49 10.8 6.4 1.3 9.4 0.1 3.6 3 1 1 4 4 4 0 Kelch motif SapA PF02199.15 CBY14515.1 - 5e-11 42.7 5.6 5e-11 42.7 5.6 2.6 3 0 0 3 3 3 1 Saposin A-type domain SapB_2 PF03489.17 CBY14515.1 - 1.2e-07 31.7 0.3 3.4e-07 30.2 0.3 1.9 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.15 CBY14515.1 - 4.9e-06 26.5 1.3 4.9e-06 26.5 1.3 2.2 3 0 0 3 3 3 1 Saposin-like type B, region 1 TPR_MLP1_2 PF07926.12 CBY14516.1 - 1.1 9.3 49.3 0.55 10.3 8.3 4.4 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein Sugarporin_N PF11471.8 CBY14516.1 - 1.9 8.5 6.9 21 5.2 0.1 3.4 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension ubiquitin PF00240.23 CBY14517.1 - 0.00053 19.7 0.0 0.00084 19.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family RNA_polI_A34 PF08208.11 CBY14517.1 - 0.0042 17.2 0.6 0.0078 16.3 0.6 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Clat_adaptor_s PF01217.20 CBY14518.1 - 1.1e-24 87.0 4.1 1.3e-24 86.7 4.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M24 PF00557.24 CBY14518.1 - 0.052 13.2 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 SIR2 PF02146.17 CBY14519.1 - 2.6e-46 157.7 0.0 5.5e-46 156.7 0.0 1.5 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 CBY14519.1 - 0.00046 19.2 0.1 0.0067 15.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 CBY14519.1 - 0.00099 18.9 0.0 0.31 10.8 0.0 2.6 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain Lectin_C PF00059.21 CBY14520.1 - 2e-07 31.7 10.0 5.3e-07 30.3 10.0 1.7 1 1 0 1 1 1 1 Lectin C-type domain VioE PF18234.1 CBY14520.1 - 0.033 14.3 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE zf-C2H2 PF00096.26 CBY14521.1 - 1.1e-16 60.2 23.0 1.3e-05 25.3 3.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY14521.1 - 1.7e-14 53.5 24.6 4.7e-09 36.3 1.2 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY14521.1 - 3.7e-10 39.7 20.2 0.0022 18.7 1.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBY14521.1 - 4e-05 23.8 6.4 7.4e-05 23.0 5.8 1.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CBY14521.1 - 0.0044 17.0 15.8 0.21 11.6 0.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger Ogr_Delta PF04606.12 CBY14521.1 - 0.01 15.8 2.3 1.4 8.9 0.1 3.2 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger FOXP-CC PF16159.5 CBY14521.1 - 0.016 15.8 9.0 0.64 10.7 0.2 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 CBY14521.1 - 0.047 13.6 10.5 0.13 12.2 0.9 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF4119 PF13494.6 CBY14521.1 - 0.062 13.5 0.0 0.39 10.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) zf-met PF12874.7 CBY14521.1 - 0.2 12.1 5.0 4.2 7.9 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CBY14521.1 - 1.1 9.6 9.3 0.17 12.2 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CHORD PF04968.12 CBY14521.1 - 1.5 9.6 8.3 1.9 9.3 2.0 2.4 1 1 1 2 2 2 0 CHORD zf-C2H2_aberr PF17017.5 CBY14521.1 - 2 8.6 3.8 29 4.7 0.9 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger Sulfatase_C PF14707.6 CBY14522.1 - 0.1 13.4 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1731 PF08338.11 CBY14522.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Sulfatase PF00884.23 CBY14523.1 - 1.4e-35 123.2 0.1 1.8e-35 122.8 0.1 1.1 1 0 0 1 1 1 1 Sulfatase ABC_transp_aux PF09822.9 CBY14523.1 - 0.028 13.9 0.1 0.051 13.0 0.0 1.5 2 0 0 2 2 2 0 ABC-type uncharacterized transport system PsaM PF07465.13 CBY14523.1 - 0.028 14.1 0.2 0.054 13.2 0.2 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) SNF PF00209.18 CBY14525.1 - 2.1e-166 554.7 30.1 2.4e-166 554.5 30.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2956 PF11169.8 CBY14526.1 - 0.035 14.3 0.8 0.074 13.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) C12orf66_like PF09404.10 CBY14527.1 - 7.4e-12 44.8 4.2 1.4e-11 43.9 0.7 2.1 1 1 1 2 2 2 2 KICSTOR complex C12orf66 like CHCH PF06747.13 CBY14529.1 - 1.6e-05 24.9 6.1 2.9e-05 24.1 6.1 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CBY14529.1 - 0.13 12.7 3.9 0.21 12.1 3.9 1.4 1 1 0 1 1 1 0 GCK domain DUF676 PF05057.14 CBY14530.1 - 5.7e-06 26.0 0.2 0.00087 18.9 0.0 2.6 3 0 0 3 3 3 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CBY14530.1 - 6.9e-05 22.7 0.0 0.00018 21.3 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CBY14530.1 - 0.0024 18.5 0.0 0.0044 17.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CBY14530.1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF726 PF05277.12 CBY14530.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) LCAT PF02450.15 CBY14530.1 - 0.06 12.5 0.0 0.5 9.5 0.0 2.2 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.13 CBY14530.1 - 0.095 12.6 0.2 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Palm_thioest PF02089.15 CBY14530.1 - 0.2 11.5 0.0 0.54 10.1 0.0 1.8 2 0 0 2 2 2 0 Palmitoyl protein thioesterase CdvA PF18822.1 CBY14530.1 - 0.22 11.3 5.0 0.28 11.0 2.3 2.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain tRNA_U5-meth_tr PF05958.11 CBY14532.1 - 0.0008 18.5 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Cript PF10235.9 CBY14533.1 - 1.2e-26 93.0 7.2 1.2e-26 93.0 7.2 1.4 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT PLATZ PF04640.14 CBY14533.1 - 0.0062 17.1 3.3 0.0062 17.1 3.3 2.5 2 1 1 3 3 3 1 PLATZ transcription factor SelR PF01641.18 CBY14533.1 - 0.031 14.3 1.6 0.035 14.2 0.6 1.7 1 1 1 2 2 2 0 SelR domain DUF2616 PF11077.8 CBY14533.1 - 0.037 13.8 5.4 0.042 13.5 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) Endonuclease_7 PF02945.15 CBY14533.1 - 0.081 12.9 6.3 0.089 12.7 4.2 2.0 1 1 1 2 2 2 0 Recombination endonuclease VII DUF2039 PF10217.9 CBY14533.1 - 0.26 11.7 16.2 1.2 9.5 16.2 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Gin PF10764.9 CBY14533.1 - 0.79 9.7 10.0 3 7.9 5.0 2.7 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin C1_2 PF03107.16 CBY14533.1 - 0.89 9.9 12.5 0.78 10.1 8.0 2.7 2 1 1 3 3 3 0 C1 domain DZR PF12773.7 CBY14533.1 - 1 9.4 11.7 38 4.4 11.7 2.7 1 1 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.15 CBY14533.1 - 1.5 8.9 15.1 0.56 10.3 2.4 3.1 2 1 1 3 3 3 0 BED zinc finger zinc_ribbon_2 PF13240.6 CBY14533.1 - 3 7.7 11.5 1.4 8.8 2.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain PMP22_Claudin PF00822.20 CBY14534.1 - 1.8e-08 34.4 9.6 2.5e-08 34.0 9.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Phage_integrase PF00589.22 CBY14535.1 - 2.1e-08 34.1 0.0 6.9e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Phage integrase family API5 PF05918.11 CBY14536.1 - 0.00018 20.5 6.0 0.00018 20.5 6.0 1.8 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) DUF3012 PF11216.8 CBY14536.1 - 0.014 15.5 0.1 0.031 14.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) PHZA_PHZB PF03284.13 CBY14536.1 - 0.03 14.0 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B zf-C4 PF00105.18 CBY14538.1 - 1e-26 93.1 12.1 1.2e-26 92.9 12.1 1.1 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 CBY14538.1 - 0.34 11.2 13.7 0.17 12.2 6.0 2.6 1 1 1 2 2 2 0 C1 domain Hormone_recep PF00104.30 CBY14539.1 - 0.00069 19.2 0.1 0.00087 18.9 0.1 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SNN_linker PF09050.10 CBY14539.1 - 0.34 10.7 2.2 0.56 10.0 2.2 1.3 1 0 0 1 1 1 0 Stannin unstructured linker Macscav_rec PF03523.13 CBY14540.1 - 0.12 12.3 0.4 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Macrophage scavenger receptor STT3 PF02516.14 CBY14541.1 - 1.7e-135 452.7 38.0 7.7e-131 437.4 34.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit AF-4 PF05110.13 CBY14542.1 - 5.8e-06 24.8 18.7 6.7e-06 24.5 18.7 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein SMG1 PF15785.5 CBY14542.1 - 1.6 7.0 7.6 0.12 10.8 1.4 1.8 1 1 1 2 2 2 0 Serine/threonine-protein kinase smg-1 HeLo PF14479.6 CBY14542.1 - 8.4 6.2 8.4 3.9 7.3 4.8 1.9 1 1 1 2 2 2 0 Prion-inhibition and propagation TPR_MLP1_2 PF07926.12 CBY14543.1 - 2.2e-20 73.0 16.6 2.2e-20 73.0 16.6 16.0 5 4 9 15 15 15 5 TPR/MLP1/MLP2-like protein DUF2746 PF10874.8 CBY14543.1 - 0.13 12.7 8.0 0.51 10.8 0.3 4.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) PQ-loop PF04193.14 CBY14544.1 - 1.8e-39 133.3 13.2 1.1e-19 70.0 2.6 3.6 3 0 0 3 3 3 2 PQ loop repeat DnaJ PF00226.31 CBY14544.1 - 4e-17 62.1 0.1 7.6e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain ER_lumen_recept PF00810.18 CBY14544.1 - 0.0062 17.4 4.3 0.87 10.4 0.6 3.3 1 1 1 2 2 2 2 ER lumen protein retaining receptor PHF5 PF03660.14 CBY14545.1 - 1.6e-47 160.0 10.0 1.9e-47 159.8 10.0 1.1 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CBY14545.1 - 0.015 13.2 4.7 0.015 13.3 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2039 PF10217.9 CBY14545.1 - 0.49 10.8 9.5 2.2 8.7 0.8 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) C1_2 PF03107.16 CBY14545.1 - 2.7 8.4 16.0 0.72 10.2 2.8 2.5 1 1 1 2 2 2 0 C1 domain DZR PF12773.7 CBY14545.1 - 4.1 7.5 14.2 4.9 7.3 1.9 2.7 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_M16 PF00675.20 CBY14546.1 - 3.9e-07 30.1 0.1 1.1e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Ufm1 PF03671.14 CBY14547.1 - 2.7e-42 142.7 0.1 3.1e-42 142.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein TM2 PF05154.16 CBY14548.1 - 2.8e-17 62.8 4.4 5.5e-17 61.8 4.4 1.5 1 0 0 1 1 1 1 TM2 domain DUF3449 PF11931.8 CBY14549.1 - 1e-27 97.1 0.0 1.6e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) DnaJ PF00226.31 CBY14549.1 - 7.6e-19 67.6 0.9 3.2e-18 65.6 0.1 2.2 2 1 0 2 2 2 1 DnaJ domain RPT PF13446.6 CBY14549.1 - 0.048 13.6 0.0 0.41 10.6 0.0 2.3 1 1 1 2 2 2 0 A repeated domain in UCH-protein Sulfotransfer_4 PF17784.1 CBY14549.1 - 0.11 12.4 0.1 1.2 8.9 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase domain PHF5 PF03660.14 CBY14550.1 - 1.6e-47 160.0 10.0 1.9e-47 159.8 10.0 1.1 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CBY14550.1 - 0.015 13.2 4.7 0.015 13.3 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2039 PF10217.9 CBY14550.1 - 0.49 10.8 9.5 2.2 8.7 0.8 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) C1_2 PF03107.16 CBY14550.1 - 2.7 8.4 16.0 0.72 10.2 2.8 2.5 1 1 1 2 2 2 0 C1 domain DZR PF12773.7 CBY14550.1 - 4.1 7.5 14.2 4.9 7.3 1.9 2.7 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_M16 PF00675.20 CBY14551.1 - 4.2e-07 30.1 0.1 1.1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Ufm1 PF03671.14 CBY14552.1 - 2.7e-42 142.7 0.1 3.1e-42 142.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein TM2 PF05154.16 CBY14553.1 - 2.7e-17 62.8 4.4 5.5e-17 61.8 4.4 1.5 1 0 0 1 1 1 1 TM2 domain DUF3449 PF11931.8 CBY14554.1 - 2.5e-65 219.8 10.5 3e-65 219.5 5.3 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 CBY14554.1 - 3.1e-25 87.6 0.5 6.7e-25 86.5 0.5 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 CBY14554.1 - 3.1e-22 78.9 6.6 6.9e-22 77.8 6.6 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 CBY14554.1 - 8.3e-09 35.2 3.4 1.2e-08 34.7 0.1 2.3 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain CotJB PF12652.7 CBY14554.1 - 0.057 13.7 0.5 0.19 12.0 0.5 1.9 1 0 0 1 1 1 0 CotJB protein zf-C2H2_4 PF13894.6 CBY14554.1 - 0.07 14.0 0.2 0.2 12.6 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2420 PF10336.9 CBY14554.1 - 0.072 13.1 0.1 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) SH2 PF00017.24 CBY14555.1 - 6.7e-12 45.4 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 SH2 domain DUF2451 PF10474.9 CBY14556.1 - 7.6e-63 212.4 1.5 4.3e-62 210.0 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 CBY14556.1 - 7.6e-29 100.9 8.3 1.8e-28 99.7 8.3 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex CsgA PF17334.2 CBY14556.1 - 0.046 14.4 1.0 0.6 10.9 0.4 2.7 2 0 0 2 2 2 0 Minor curli fiber component A UCH_N PF16674.5 CBY14556.1 - 0.19 11.7 4.7 4.2 7.4 0.6 3.0 2 0 0 2 2 2 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 FGGY_N PF00370.21 CBY14557.1 - 3.4e-76 256.0 0.2 5e-76 255.5 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CBY14557.1 - 3.2e-62 209.8 0.4 5.7e-62 209.0 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CBY14558.1 - 7.9e-65 218.8 0.1 1.3e-64 218.1 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CBY14558.1 - 2.8e-62 210.0 0.4 4.9e-62 209.2 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Clat_adaptor_s PF01217.20 CBY14559.1 - 4.9e-19 68.7 1.3 6.1e-19 68.4 1.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Lactamase_B PF00753.27 CBY14560.1 - 1e-13 51.8 4.6 3.7e-11 43.4 4.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY14560.1 - 0.023 14.2 1.7 0.039 13.5 1.7 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain cNMP_binding PF00027.29 CBY14561.1 - 9.8e-41 137.7 0.2 2.1e-15 56.5 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CBY14561.1 - 1.7e-18 67.5 0.0 4.7e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase Kelch_2 PF07646.15 CBY14562.1 - 0.00019 21.3 0.1 2.1 8.5 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY14562.1 - 0.0067 16.4 1.9 0.035 14.1 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY14562.1 - 0.46 10.9 2.9 2.6 8.5 0.0 2.9 2 1 1 3 3 3 0 Kelch motif AAA PF00004.29 CBY14563.1 - 1.9e-33 115.7 0.0 5.9e-33 114.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBY14563.1 - 1.2e-05 25.1 0.0 5e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBY14563.1 - 4.5e-05 23.5 0.0 0.0017 18.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY14563.1 - 0.00015 22.1 0.0 0.021 15.1 0.0 2.8 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 CBY14563.1 - 0.00023 20.9 0.0 0.0005 19.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CBY14563.1 - 0.00041 20.8 0.1 0.0048 17.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 CBY14563.1 - 0.00045 19.5 0.0 0.0017 17.7 0.0 1.8 1 1 1 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBY14563.1 - 0.00048 19.6 0.1 0.0012 18.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CBY14563.1 - 0.0022 18.1 0.0 0.0064 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CBY14563.1 - 0.0038 17.2 0.2 0.034 14.1 0.0 2.5 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 CBY14563.1 - 0.0057 17.2 0.0 0.027 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CBY14563.1 - 0.0073 16.7 0.0 0.023 15.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 CBY14563.1 - 0.0077 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBY14563.1 - 0.0084 16.5 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 CBY14563.1 - 0.0086 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CBY14563.1 - 0.0095 15.9 0.1 0.027 14.4 0.1 1.8 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 CBY14563.1 - 0.015 14.7 0.2 2.2 7.6 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein ATPase_2 PF01637.18 CBY14563.1 - 0.03 14.3 0.8 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 CBY14563.1 - 0.042 13.7 0.0 0.43 10.4 0.0 2.2 1 1 0 1 1 1 0 Bacterial dnaA protein Viral_helicase1 PF01443.18 CBY14563.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 CBY14563.1 - 0.096 12.3 0.4 1.7 8.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CBY14563.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CBY14563.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 CBY14563.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 CBY14563.1 - 0.16 11.7 0.5 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.24 CBY14564.1 - 8e-85 285.3 15.5 1.2e-84 284.7 15.5 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TM231 PF10149.9 CBY14565.1 - 2.7e-15 56.5 3.3 1.7e-14 53.9 3.3 2.0 1 1 0 1 1 1 1 Transmembrane protein 231 VPS13_mid_rpt PF16910.5 CBY14565.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Repeating coiled region of VPS13 DHHC PF01529.20 CBY14566.1 - 1.2e-31 109.5 10.0 1.2e-31 109.5 10.0 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase UbiA PF01040.18 CBY14566.1 - 0.093 12.0 2.4 0.2 10.9 0.2 2.0 2 0 0 2 2 2 0 UbiA prenyltransferase family DHHC PF01529.20 CBY14567.1 - 8.8e-38 129.4 10.1 8.8e-38 129.4 10.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1211 PF06736.11 CBY14567.1 - 0.98 9.9 5.0 0.26 11.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) p25-alpha PF05517.12 CBY14568.1 - 5e-60 202.2 16.8 5.7e-60 202.0 16.8 1.0 1 0 0 1 1 1 1 p25-alpha zf-3CxxC PF13695.6 CBY14568.1 - 0.15 12.5 5.3 1.3 9.5 5.3 2.0 1 1 0 1 1 1 0 Zinc-binding domain Thyroglobulin_1 PF00086.18 CBY14569.1 - 2.1e-26 91.4 14.9 3.7e-12 45.7 0.2 4.7 4 1 0 4 4 4 4 Thyroglobulin type-1 repeat SH3_2 PF07653.17 CBY14571.1 - 1.1e-09 37.8 0.0 2.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CBY14571.1 - 4.6e-07 29.6 0.2 1.5e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY14571.1 - 0.00012 21.6 0.7 0.00083 18.9 0.3 2.6 2 1 0 2 2 2 1 SH3 domain Foamy_BEL PF03274.14 CBY14572.1 - 0.0048 16.3 1.5 0.0072 15.7 1.5 1.2 1 0 0 1 1 1 1 Foamy virus BEL 1/2 protein MNNL PF07657.13 CBY14573.1 - 1.4e-21 76.3 1.7 1.9e-21 75.9 1.7 1.1 1 0 0 1 1 1 1 N terminus of Notch ligand PRKCSH-like PF12999.7 CBY14573.1 - 0.054 13.3 3.6 0.069 12.9 3.6 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Kringle PF00051.18 CBY14574.1 - 1.5e-18 66.9 6.0 3.3e-18 65.8 6.0 1.7 1 0 0 1 1 1 1 Kringle domain Ldl_recept_b PF00058.17 CBY14574.1 - 2.6e-05 24.6 11.2 0.91 10.1 0.1 5.4 5 0 0 5 5 5 2 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 CBY14574.1 - 7.9e-05 22.9 3.1 7.9e-05 22.9 3.1 2.7 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site DUF2627 PF11118.8 CBY14574.1 - 0.1 13.2 0.5 3.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) DUF4366 PF14283.6 CBY14574.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) EGF PF00008.27 CBY14574.1 - 6.1 7.2 12.5 18 5.8 2.2 2.9 2 0 0 2 2 2 0 EGF-like domain Kelch_2 PF07646.15 CBY14575.1 - 1.2e-05 25.0 0.3 1.9 8.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY14575.1 - 0.00082 19.6 0.1 0.58 10.5 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CBY14575.1 - 0.02 14.9 1.3 0.81 9.7 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 CBY14575.1 - 0.036 14.1 0.3 20 5.3 0.0 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain RRM_1 PF00076.22 CBY14576.1 - 3.5e-19 68.4 0.0 7.8e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coilin_N PF15862.5 CBY14576.1 - 0.023 14.5 3.7 0.13 12.1 0.2 2.1 2 0 0 2 2 2 0 Coilin N-terminus GlcNAc-1_reg PF18440.1 CBY14576.1 - 0.17 12.1 0.3 23 5.3 0.0 2.2 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain PET117 PF15786.5 CBY14576.1 - 5.9 7.2 8.1 7.1 7.0 1.6 2.3 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Ank_2 PF12796.7 CBY14577.1 - 6.8e-99 324.6 44.0 4.3e-17 62.5 0.6 12.4 4 3 10 15 15 15 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY14577.1 - 2.9e-85 279.6 40.0 2e-11 44.1 0.6 18.2 11 6 9 20 20 20 17 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY14577.1 - 7.8e-82 268.3 40.3 6.8e-10 39.0 0.3 19.3 10 7 10 20 20 20 17 Ankyrin repeats (many copies) Ank PF00023.30 CBY14577.1 - 1.5e-71 233.9 38.0 7.6e-07 29.3 0.4 22.1 22 1 0 22 22 22 13 Ankyrin repeat Ank_3 PF13606.6 CBY14577.1 - 3e-65 208.4 30.8 8.8e-05 22.6 0.0 23.3 24 0 0 24 24 24 14 Ankyrin repeat IMPDH PF00478.25 CBY14578.1 - 0.019 14.0 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IMPDH PF00478.25 CBY14579.1 - 3.5e-120 401.1 3.2 4e-120 400.9 3.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CBY14579.1 - 8.5e-09 35.2 1.0 1.2e-06 28.2 1.0 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 CBY14579.1 - 9.4e-07 28.5 0.7 9.1e-06 25.3 0.7 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 CBY14579.1 - 2e-05 23.9 0.1 3.9e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 CBY14579.1 - 0.00018 20.6 3.6 0.00077 18.6 3.6 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 CBY14579.1 - 0.00068 19.0 0.5 0.0036 16.7 0.4 2.0 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG YpsA PF06908.11 CBY14579.1 - 0.0082 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 YspA SLOG family CBS PF00571.28 CBY14579.1 - 0.029 14.8 0.0 0.65 10.5 0.0 2.5 2 0 0 2 2 2 0 CBS domain DHO_dh PF01180.21 CBY14579.1 - 0.032 13.5 0.5 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 CBY14579.1 - 0.19 10.9 3.1 0.22 10.6 0.9 2.1 2 1 1 3 3 3 0 Conserved region in glutamate synthase SCAN PF02023.17 CBY14580.1 - 0.73 9.7 4.7 9.6 6.1 0.2 2.9 3 0 0 3 3 3 0 SCAN domain Maf PF02545.14 CBY14581.1 - 8.5e-41 139.6 0.0 1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein MTABC_N PF16185.5 CBY14582.1 - 0.0076 15.8 2.6 0.0099 15.4 2.6 1.2 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region Got1 PF04178.12 CBY14582.1 - 0.0079 16.6 0.6 0.0079 16.6 0.6 2.5 3 1 0 3 3 3 1 Got1/Sft2-like family DUF3623 PF12291.8 CBY14582.1 - 0.023 13.9 0.1 0.04 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) DUF1129 PF06570.11 CBY14582.1 - 0.047 13.2 4.5 0.11 12.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) ABC_membrane PF00664.23 CBY14583.1 - 1e-61 209.0 28.6 1.1e-32 113.7 14.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY14583.1 - 1.4e-50 171.3 0.1 8.5e-27 94.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBY14583.1 - 1e-11 44.7 1.4 1.4e-07 31.2 0.0 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBY14583.1 - 2.9e-06 26.9 1.6 0.05 13.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBY14583.1 - 2.4e-05 24.3 0.1 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CBY14583.1 - 3.3e-05 24.0 0.5 0.11 12.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY14583.1 - 0.00013 22.3 0.7 0.13 12.6 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain DUF87 PF01935.17 CBY14583.1 - 0.00019 21.6 2.0 0.028 14.5 0.2 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 CBY14583.1 - 0.00037 20.8 0.7 0.12 12.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 CBY14583.1 - 0.0018 18.1 0.1 1.3 8.8 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 CBY14583.1 - 0.0022 17.5 0.3 1.4 8.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region MeaB PF03308.16 CBY14583.1 - 0.0027 16.7 0.2 1 8.3 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 CBY14583.1 - 0.0028 16.8 0.1 0.54 9.3 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein cobW PF02492.19 CBY14583.1 - 0.003 17.2 0.1 0.27 10.8 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 CBY14583.1 - 0.009 15.8 0.2 0.049 13.4 0.1 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 CBY14583.1 - 0.012 14.9 0.8 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 CBY14583.1 - 0.014 15.6 0.5 6.7 6.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 CBY14583.1 - 0.022 15.2 3.9 3.5 8.1 0.1 2.9 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 CBY14583.1 - 0.024 15.1 0.7 14 6.1 0.1 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CBY14583.1 - 0.03 14.0 2.1 1.5 8.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain NTPase_1 PF03266.15 CBY14583.1 - 0.035 14.0 0.3 0.76 9.7 0.0 2.7 3 0 0 3 3 2 0 NTPase TrwB_AAD_bind PF10412.9 CBY14583.1 - 0.039 12.9 0.3 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain GTP_EFTU PF00009.27 CBY14583.1 - 0.044 13.3 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBY14583.1 - 0.052 13.6 3.9 0.89 9.6 0.6 3.0 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 CBY14583.1 - 0.057 12.7 0.2 0.39 10.0 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 CBY14583.1 - 0.061 12.8 0.3 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_21 PF13304.6 CBY14583.1 - 0.061 13.1 1.6 11 5.7 0.0 4.1 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CBY14583.1 - 0.069 13.7 0.2 12 6.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CBY14583.1 - 0.12 12.1 0.2 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 CBY14583.1 - 0.14 11.3 1.8 4 6.5 0.2 2.5 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 CBY14583.1 - 0.16 11.3 0.2 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Septin ATP-synt_ab PF00006.25 CBY14583.1 - 0.18 11.4 0.1 9.4 5.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.14 CBY14583.1 - 1 8.5 4.5 10 5.2 0.7 3.1 3 1 0 3 3 3 0 KAP family P-loop domain Sulfotransfer_4 PF17784.1 CBY14584.1 - 8.2e-57 192.5 0.0 1.1e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain DUF3463 PF11946.8 CBY14584.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) Sulfotransfer_3 PF13469.6 CBY14584.1 - 0.25 11.7 0.4 1.9 8.8 0.4 2.2 1 1 0 1 1 1 0 Sulfotransferase family PH PF00169.29 CBY14585.1 - 2.6e-05 24.7 0.2 7.4e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 PH domain p450 PF00067.22 CBY14586.1 - 3.6e-49 167.8 1.0 6.2e-49 167.0 0.5 1.5 2 0 0 2 2 2 1 Cytochrome P450 HTH_Tnp_4 PF13613.6 CBY14586.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Astacin PF01400.24 CBY14589.1 - 2.7e-28 98.9 0.0 4.8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY14589.1 - 8.2e-11 41.9 80.1 3.3e-05 24.0 12.7 6.9 6 0 0 6 6 6 3 Calcium-binding EGF domain EGF_3 PF12947.7 CBY14589.1 - 0.00098 19.3 8.4 0.00098 19.3 8.4 6.0 5 0 0 5 5 5 2 EGF domain cEGF PF12662.7 CBY14589.1 - 0.0016 18.4 34.6 0.008 16.1 1.3 6.1 5 0 0 5 5 5 3 Complement Clr-like EGF-like RRM_1 PF00076.22 CBY14592.1 - 0.0093 15.8 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pinin_SDK_memA PF04696.13 CBY14592.1 - 0.83 9.7 6.0 0.25 11.4 2.5 2.1 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region EF-hand_7 PF13499.6 CBY14598.1 - 8.5e-25 87.0 4.2 2.4e-15 56.8 0.5 3.3 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBY14598.1 - 1.3e-24 83.8 7.1 5.4e-07 28.7 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBY14598.1 - 4.2e-22 76.2 3.3 6.2e-06 25.7 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBY14598.1 - 3e-19 67.5 8.5 4.1e-06 26.0 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY14598.1 - 8.8e-14 51.1 8.2 3e-06 27.0 0.3 4.3 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY14598.1 - 0.00012 22.4 0.6 6.4 7.1 0.0 3.2 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY14598.1 - 0.00019 21.3 2.2 3.5 7.6 0.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CBY14598.1 - 0.0021 18.4 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 CBY14598.1 - 0.0091 15.9 1.2 16 5.4 0.0 3.3 2 1 1 4 4 4 0 Caleosin related protein Homeodomain PF00046.29 CBY14598.1 - 0.027 14.3 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain Homez PF11569.8 CBY14598.1 - 0.031 13.7 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Dockerin_1 PF00404.18 CBY14598.1 - 0.052 13.7 0.0 5.4 7.3 0.0 2.9 3 0 0 3 3 3 0 Dockerin type I domain S10_plectin PF03501.15 CBY14598.1 - 0.082 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain NADPH_Ox PF08414.10 CBY14598.1 - 0.17 12.2 1.1 4.7 7.6 0.0 2.7 1 1 0 2 2 2 0 Respiratory burst NADPH oxidase PMBR PF09373.10 CBY14598.1 - 0.19 11.9 0.0 68 3.9 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat ResIII PF04851.15 CBY14599.1 - 0.074 13.0 0.1 0.1 12.6 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Kelch_6 PF13964.6 CBY14601.1 - 2.9e-24 84.5 0.1 3.7e-07 30.2 0.0 4.6 1 1 3 4 4 4 4 Kelch motif Kelch_1 PF01344.25 CBY14601.1 - 6.3e-24 83.3 0.1 6.2e-08 32.1 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CBY14601.1 - 1.5e-15 56.9 0.0 1.2e-05 25.2 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY14601.1 - 5e-15 55.4 0.0 8.8e-05 22.7 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY14601.1 - 7.9e-13 48.1 0.0 0.00069 19.5 0.1 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CBY14601.1 - 8.3e-08 31.9 0.0 0.53 10.3 0.0 4.9 4 1 0 4 4 4 2 Kelch motif BACK PF07707.15 CBY14601.1 - 7.4e-06 26.0 0.1 1.5e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CBY14602.1 - 0.026 14.5 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY14602.1 - 0.032 14.2 0.1 0.092 12.8 0.0 1.8 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CBY14602.1 - 0.079 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 CBY14603.1 - 4.6e-06 26.5 0.3 0.0022 18.0 0.1 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY14603.1 - 7.9e-06 26.0 1.6 0.011 16.0 0.2 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CBY14603.1 - 0.14 11.7 5.5 0.12 12.0 1.4 3.0 3 1 0 3 3 3 0 Kelch motif CUB PF00431.20 CBY14604.1 - 6.5e-11 42.5 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 CUB domain DUF3887 PF13026.6 CBY14604.1 - 0.13 13.1 0.0 3.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) PA26 PF04636.13 CBY14605.1 - 1.1e-33 116.9 0.2 1.5e-33 116.4 0.2 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Acatn PF13000.7 CBY14606.1 - 5.1e-31 107.8 17.2 2e-25 89.3 10.1 2.9 1 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 Band_7 PF01145.25 CBY14607.1 - 1.4e-18 67.5 0.0 1.4e-18 67.5 0.0 1.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family zf-CRD PF17979.1 CBY14607.1 - 4.4 7.4 5.0 16 5.6 2.2 2.4 2 1 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Band_7 PF01145.25 CBY14608.1 - 5e-07 29.9 0.0 5.8e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7 PF01145.25 CBY14609.1 - 1.9e-12 47.6 0.0 2.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Mito_carr PF00153.27 CBY14610.1 - 9.2e-40 134.5 5.5 3.8e-15 55.6 0.3 3.0 2 1 0 3 3 3 3 Mitochondrial carrier protein PMM PF03332.13 CBY14611.1 - 5.4e-94 314.1 1.8 6.2e-94 313.9 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CBY14611.1 - 1.3e-09 38.2 0.1 7.8e-09 35.6 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBY14611.1 - 0.012 15.7 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY14611.1 - 0.11 12.8 0.0 0.41 10.9 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.32 CBY14612.1 - 4.9e-48 160.1 18.7 2.6e-08 34.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY14612.1 - 1.9e-11 44.1 0.4 0.0095 16.2 0.0 4.9 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY14612.1 - 8.1e-07 28.7 0.0 0.0068 15.8 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 CBY14612.1 - 0.00041 19.1 1.1 3.7 6.1 0.1 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBY14612.1 - 0.0011 18.0 0.1 3.1 6.7 0.0 3.6 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CBY14612.1 - 0.0029 16.2 0.0 0.69 8.4 0.1 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 CBY14612.1 - 0.68 9.9 3.2 63 3.7 0.1 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TIC20 PF16166.5 CBY14613.1 - 1.6 8.5 12.3 0.045 13.5 4.0 2.2 1 1 1 2 2 2 0 Chloroplast import apparatus Tic20-like UBA_4 PF14555.6 CBY14615.1 - 5.9e-05 22.8 0.1 0.00014 21.6 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain EGF_3 PF12947.7 CBY14616.1 - 2.8e-05 24.2 10.9 2.8e-05 24.2 10.9 3.0 3 0 0 3 3 3 2 EGF domain EGF PF00008.27 CBY14616.1 - 0.00062 20.0 6.7 0.00062 20.0 6.7 3.5 3 1 0 3 3 3 2 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY14616.1 - 3.6 8.0 14.0 2.2 8.6 6.5 2.9 2 0 0 2 2 2 0 Pvs28 EGF domain dsrm PF00035.26 CBY14617.1 - 2.5e-11 44.1 0.3 7.2e-07 29.8 0.0 3.6 3 0 0 3 3 3 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CBY14617.1 - 7e-06 26.1 0.1 3.1 8.0 0.0 3.6 3 0 0 3 3 3 3 Dicer dimerisation domain DZF PF07528.14 CBY14617.1 - 0.041 13.5 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 DZF domain Rrn6 PF10214.9 CBY14617.1 - 0.27 9.7 3.8 0.58 8.6 3.8 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Tropomyosin PF00261.20 CBY14618.1 - 7.6e-05 22.2 40.0 0.00028 20.3 40.0 1.8 1 1 0 1 1 1 1 Tropomyosin Ribosomal_L18p PF00861.22 CBY14618.1 - 0.015 15.7 0.4 0.015 15.7 0.4 1.9 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DUF3683 PF12447.8 CBY14618.1 - 5.3 7.2 10.9 10 6.3 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3683) CBM_14 PF01607.24 CBY14619.1 - 2.8e-13 49.8 6.1 4.4e-13 49.2 6.1 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF5401 PF17380.2 CBY14619.1 - 0.11 10.5 0.5 0.11 10.5 0.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Trypsin PF00089.26 CBY14620.1 - 4.4e-44 150.9 0.7 4.4e-44 150.9 0.7 2.2 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 CBY14620.1 - 6.7e-33 113.3 2.8 6.1e-16 58.7 0.2 3.3 3 0 0 3 3 3 2 CUB domain FXa_inhibition PF14670.6 CBY14620.1 - 0.02 15.2 15.3 0.13 12.6 15.3 2.6 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site DUF1986 PF09342.11 CBY14620.1 - 0.04 14.3 0.1 0.076 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) LTD PF00932.19 CBY14620.1 - 0.046 14.1 5.6 2.5 8.5 2.2 3.3 3 0 0 3 3 3 0 Lamin Tail Domain SprA-related PF12118.8 CBY14620.1 - 9.3 5.3 10.7 21 4.1 10.7 1.5 1 0 0 1 1 1 0 SprA-related family Prot_ATP_ID_OB PF16450.5 CBY14623.1 - 0.015 15.2 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Prot_ATP_OB_N PF17758.1 CBY14623.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Rhomboid PF01694.22 CBY14624.1 - 1.5e-29 103.0 13.7 1.5e-29 103.0 13.7 1.7 2 0 0 2 2 2 1 Rhomboid family Dimer_Tnp_hAT PF05699.14 CBY14624.1 - 1.8e-05 24.5 0.8 4.9e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region ECF_trnsprt PF12822.7 CBY14624.1 - 9.3 6.3 19.2 1.5e+03 -0.9 19.3 2.2 1 1 0 1 1 1 0 ECF transporter, substrate-specific component Phospholip_A2_1 PF00068.19 CBY14625.1 - 4.3e-17 62.6 4.4 4.3e-17 62.6 4.4 1.5 2 0 0 2 2 2 1 Phospholipase A2 Kelch_2 PF07646.15 CBY14626.1 - 0.00076 19.4 0.1 3.7 7.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY14626.1 - 0.00083 19.6 0.1 2.5 8.5 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY14626.1 - 0.069 13.2 0.6 4.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY14626.1 - 0.074 13.1 1.2 0.33 11.0 0.0 2.7 3 0 0 3 3 3 0 Kelch motif EF-hand_7 PF13499.6 CBY14627.1 - 7.6e-15 55.1 0.8 9e-06 26.1 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY14627.1 - 8.3e-13 46.9 8.9 2.8e-06 26.5 0.0 3.7 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY14627.1 - 7.1e-12 44.2 2.9 0.00027 20.6 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY14627.1 - 2.5e-10 39.4 6.7 0.00041 19.7 3.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY14627.1 - 1.3e-09 37.8 2.7 1.4e-05 24.8 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY14627.1 - 0.031 14.6 0.2 1.2 9.4 0.0 2.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY14627.1 - 0.23 11.4 0.1 0.23 11.4 0.1 3.1 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Guanylate_cyc PF00211.20 CBY14628.1 - 1e-38 132.8 0.3 1.4e-38 132.3 0.3 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Med25 PF11232.8 CBY14629.1 - 1.9e-38 131.8 0.8 1.9e-38 131.8 0.8 2.0 2 0 0 2 2 2 1 Mediator complex subunit 25 PTOV activation and synapsin 2 Med25_VWA PF11265.8 CBY14629.1 - 2.4e-28 99.4 0.0 4.1e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Ndc1_Nup PF09531.10 CBY14629.1 - 5.1 5.7 11.1 7.9 5.0 11.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 CBY14629.1 - 5.6 6.9 45.3 0.076 13.0 35.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NICE-3 PF07406.11 CBY14630.1 - 3.2e-16 59.8 0.2 4.5e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 NICE-3 protein DUF1298 PF06974.13 CBY14630.1 - 0.029 14.3 2.5 1.7 8.6 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1298) BORCS6 PF10157.9 CBY14630.1 - 0.063 13.5 0.1 0.13 12.4 0.0 1.5 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 ELO PF01151.18 CBY14632.1 - 9.3e-59 199.0 19.7 1.1e-58 198.7 19.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CENP-O PF09496.10 CBY14632.1 - 0.17 11.9 0.4 0.25 11.3 0.4 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component ATP_bind_3 PF01171.20 CBY14633.1 - 7.3e-15 55.2 0.0 2e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 PP-loop family DUF5531 PF17671.1 CBY14633.1 - 1.2 9.0 4.4 4.2 7.2 2.6 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5531) 7tm_1 PF00001.21 CBY14635.1 - 0.00028 20.3 5.7 0.00028 20.3 5.7 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Ig_3 PF13927.6 CBY14636.1 - 1.1e-36 125.3 24.6 9.7e-14 51.7 0.1 6.8 7 0 0 7 7 7 4 Immunoglobulin domain Ig_2 PF13895.6 CBY14636.1 - 1.1e-29 102.6 14.3 4.2e-10 39.8 0.0 6.0 6 0 0 6 6 6 4 Immunoglobulin domain I-set PF07679.16 CBY14636.1 - 3.2e-25 88.0 20.2 9.1e-09 35.3 0.0 7.9 7 2 0 7 7 7 3 Immunoglobulin I-set domain fn3 PF00041.21 CBY14636.1 - 1.9e-19 69.8 1.4 3.8e-14 52.8 0.2 3.2 3 0 0 3 3 2 2 Fibronectin type III domain ig PF00047.25 CBY14636.1 - 1.3e-17 63.7 20.7 2.6e-07 30.7 0.0 7.3 6 2 0 6 6 6 3 Immunoglobulin domain Ig_5 PF16681.5 CBY14636.1 - 4.5e-08 33.4 10.1 2.5e-06 27.8 0.0 5.7 5 1 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 CBY14636.1 - 2.6e-07 30.6 5.6 0.058 13.5 0.3 4.6 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 CBY14636.1 - 3.1e-07 30.6 5.1 0.0003 21.0 0.0 4.6 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 CBY14636.1 - 4e-06 27.0 16.2 0.77 10.0 0.0 8.0 7 3 1 8 8 8 2 Immunoglobulin V-set domain Interfer-bind PF09294.10 CBY14636.1 - 0.01 16.1 0.3 0.078 13.3 0.0 2.7 3 0 0 3 3 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.5 CBY14636.1 - 0.01 16.1 1.3 0.035 14.4 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4959) Pur_ac_phosph_N PF16656.5 CBY14636.1 - 0.013 16.1 19.2 0.015 15.9 1.4 4.6 3 2 1 4 4 4 0 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 CBY14636.1 - 0.077 13.2 0.5 0.97 9.6 0.1 2.8 2 1 0 2 2 2 0 Fibronectin type III domain PP2C PF00481.21 CBY14637.1 - 9.7e-39 133.5 0.1 6.1e-33 114.5 0.3 2.0 1 1 1 2 2 2 2 Protein phosphatase 2C Glyco_hydro_20 PF00728.22 CBY14639.1 - 4e-49 167.9 0.0 4.7e-40 138.1 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Sulfotransfer_3 PF13469.6 CBY14640.1 - 5.4e-44 151.2 0.0 1.1e-43 150.2 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY14640.1 - 3.8e-11 43.0 0.2 1.3e-10 41.2 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 CBY14640.1 - 0.008 16.0 1.0 0.032 14.1 1.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY14641.1 - 0.00081 19.8 0.1 0.0014 19.1 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY14641.1 - 0.0026 17.3 0.2 0.0049 16.4 0.2 1.5 1 0 0 1 1 1 1 Sulfotransferase domain DnaJ PF00226.31 CBY14642.1 - 1.1e-05 25.5 0.1 0.00055 20.0 0.1 2.2 1 1 0 1 1 1 1 DnaJ domain Pkinase_Tyr PF07714.17 CBY14644.1 - 2.7e-06 26.9 0.2 1.6e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PIP49_C PF12260.8 CBY14644.1 - 4.8e-05 23.1 0.1 7.6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase PF00069.25 CBY14644.1 - 0.0053 16.2 0.1 0.1 12.0 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain RICTOR_M PF14666.6 CBY14644.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain CbiC PF02570.15 CBY14644.1 - 0.2 11.3 0.0 0.97 9.1 0.0 1.8 2 0 0 2 2 2 0 Precorrin-8X methylmutase 7tm_1 PF00001.21 CBY14645.1 - 5.3e-13 48.9 14.7 7e-13 48.5 10.5 2.7 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) AMP-binding PF00501.28 CBY14646.1 - 5.1e-49 167.0 0.0 6.1e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Nebulin PF00880.18 CBY14647.1 - 4.3e-46 154.3 80.6 3.1e-08 33.4 0.1 17.8 20 0 0 20 20 20 12 Nebulin repeat SH3_9 PF14604.6 CBY14647.1 - 9.6e-12 44.6 0.1 2.1e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY14647.1 - 1.6e-10 40.4 0.0 4.3e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY14647.1 - 0.00012 21.7 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Phospholip_A2_1 PF00068.19 CBY14648.1 - 3e-21 76.0 7.8 3e-21 76.0 7.8 1.6 2 0 0 2 2 2 1 Phospholipase A2 Pkinase PF00069.25 CBY14649.1 - 3.3e-22 79.1 1.0 2.1e-21 76.4 0.0 2.5 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14649.1 - 1.4e-06 27.8 0.2 2e-05 24.0 0.0 2.8 2 2 0 2 2 2 1 Protein tyrosine kinase HMMR_N PF15905.5 CBY14649.1 - 0.28 10.6 34.3 0.6 9.5 34.3 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cast PF10174.9 CBY14649.1 - 0.47 8.6 38.2 2.8 6.0 38.2 1.8 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Prominin PF05478.11 CBY14649.1 - 2.4 6.0 15.1 3.3 5.6 15.1 1.1 1 0 0 1 1 1 0 Prominin Neur_chan_memb PF02932.16 CBY14649.1 - 4.6 7.2 7.8 7.7 6.5 7.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lectin_N PF03954.14 CBY14649.1 - 5.1 6.8 8.1 0.61 9.8 3.2 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Ground-like PF04155.18 CBY14650.1 - 0.1 13.2 0.2 0.12 13.0 0.2 1.1 1 0 0 1 1 1 0 Ground-like domain Dicty_REP PF05086.12 CBY14651.1 - 0.16 10.0 1.8 0.15 10.0 1.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2773 PF10971.8 CBY14651.1 - 0.19 11.8 0.1 0.37 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) DUF2141 PF09912.9 CBY14651.1 - 0.24 11.3 1.5 0.33 10.9 0.2 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) Collagen PF01391.18 CBY14652.1 - 5.2e-17 61.4 63.6 3.2e-10 39.6 30.7 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) EF-hand_1 PF00036.32 CBY14654.1 - 4.2e-20 69.7 25.3 0.00042 19.6 0.5 6.3 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 CBY14654.1 - 1e-17 62.5 21.4 4.6e-05 23.0 0.7 6.3 6 0 0 6 6 6 5 EF-hand domain EF-hand_7 PF13499.6 CBY14654.1 - 1.5e-17 63.8 21.0 3.8e-08 33.7 3.4 3.9 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 CBY14654.1 - 3.9e-12 45.8 20.3 0.00023 21.0 0.1 6.1 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 CBY14654.1 - 4.5e-10 38.6 19.7 0.0005 19.4 0.5 5.8 6 0 0 6 6 6 3 EF hand SPARC_Ca_bdg PF10591.9 CBY14654.1 - 4.9e-05 23.6 15.6 0.0019 18.5 0.4 4.0 1 1 3 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Spc7_N PF15402.6 CBY14654.1 - 0.062 11.6 0.4 0.083 11.1 0.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF1140 PF06600.11 CBY14654.1 - 0.078 13.4 0.4 0.078 13.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) EF-hand_10 PF14788.6 CBY14654.1 - 1.8 8.5 12.3 0.74 9.7 2.2 4.3 5 0 0 5 5 5 0 EF hand DAO PF01266.24 CBY14655.1 - 5.3e-39 134.8 0.0 6.5e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBY14655.1 - 1.8e-06 27.4 0.4 0.0029 16.9 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBY14655.1 - 0.00015 20.6 2.0 0.007 15.1 0.2 2.6 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 CBY14655.1 - 0.00034 19.8 0.3 0.019 14.1 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CBY14655.1 - 0.00049 20.3 0.7 0.00049 20.3 0.7 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBY14655.1 - 0.0011 18.2 0.4 0.0041 16.3 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 CBY14655.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBY14655.1 - 0.0013 18.0 0.2 0.0079 15.5 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY14655.1 - 0.0091 15.3 0.2 0.016 14.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CBY14655.1 - 0.034 14.7 4.8 0.04 14.5 0.3 3.4 4 1 1 5 5 5 0 Pyridine nucleotide-disulphide oxidoreductase DUF4895 PF16236.5 CBY14655.1 - 0.036 13.8 0.2 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4895) ApbA PF02558.16 CBY14655.1 - 0.058 13.0 0.2 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MULE PF10551.9 CBY14656.1 - 0.021 15.2 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 MULE transposase domain DUF4775 PF16001.5 CBY14656.1 - 0.3 10.4 3.8 0.43 9.9 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Pkinase PF00069.25 CBY14660.1 - 2.2e-07 30.5 0.0 4.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14660.1 - 0.0001 21.7 0.1 0.00026 20.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RVT_1 PF00078.27 CBY14663.1 - 2.3e-12 46.9 0.0 4e-07 29.8 0.0 2.8 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_1 PF01344.25 CBY14664.1 - 0.00014 21.4 0.4 1.2 8.8 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY14664.1 - 0.00025 20.9 0.1 0.59 10.2 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY14664.1 - 0.0086 16.0 2.7 0.21 11.6 0.0 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY14664.1 - 0.0098 16.2 3.0 1.1 9.6 0.0 3.5 2 1 1 3 3 3 2 Kelch motif zf-C2H2 PF00096.26 CBY14665.1 - 6.5e-06 26.3 12.6 0.017 15.5 2.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY14665.1 - 0.00077 19.8 2.2 0.00077 19.8 2.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY14665.1 - 0.032 15.1 1.9 0.032 15.1 1.9 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 CBY14665.1 - 1 9.7 4.3 0.37 11.1 0.3 2.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding RT_RNaseH PF17917.1 CBY14667.1 - 2.7e-30 104.7 0.2 5e-30 103.9 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY14667.1 - 1.5e-28 98.7 0.0 2.9e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY14667.1 - 1.7e-23 83.0 0.2 1.6e-22 79.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CBY14667.1 - 7.3e-17 61.6 0.2 8.5e-16 58.1 0.1 2.6 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY14667.1 - 3.4e-14 52.7 0.0 9.6e-14 51.2 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS240 PF13610.6 CBY14667.1 - 0.0074 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 CBY14667.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Kelch_2 PF07646.15 CBY14668.1 - 0.00077 19.4 0.8 1.2 9.3 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY14668.1 - 0.002 18.3 0.8 0.97 9.8 0.0 3.7 3 1 1 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CBY14668.1 - 0.0093 15.9 1.7 0.11 12.5 0.0 3.0 3 0 0 3 3 3 1 Kelch motif MH1 PF03165.16 CBY14669.1 - 4.5e-19 68.6 2.3 6.2e-19 68.1 0.9 1.9 2 0 0 2 2 2 1 MH1 domain Securin PF04856.13 CBY14670.1 - 0.035 14.1 1.8 0.063 13.2 1.8 1.4 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor Retrotrans_gag PF03732.17 CBY14670.1 - 0.052 13.8 1.4 0.071 13.4 0.2 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein Kelch_5 PF13854.6 CBY14671.1 - 3e-07 30.3 0.9 0.0013 18.6 0.3 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBY14671.1 - 0.0045 17.2 0.3 0.41 11.0 0.2 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CBY14671.1 - 0.026 14.5 1.1 0.16 12.0 0.5 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CBY14671.1 - 0.12 12.0 4.3 2.7 7.7 2.3 3.1 2 1 1 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY14671.1 - 0.12 12.3 3.7 0.67 10.0 2.0 2.4 2 1 0 2 2 2 0 Galactose oxidase, central domain Pan3_PK PF18101.1 CBY14673.1 - 2.1e-34 118.5 0.0 2.5e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Op_neuropeptide PF08035.11 CBY14673.1 - 0.14 12.0 0.2 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Opioids neuropeptide DUF2399 PF09664.10 CBY14674.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) MAP65_ASE1 PF03999.12 CBY14674.1 - 6.1 5.4 13.9 0.014 14.1 1.3 1.9 1 1 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) CCT_2 PF09425.10 CBY14675.1 - 0.15 12.0 0.8 1.9 8.5 0.1 2.1 2 0 0 2 2 2 0 Divergent CCT motif Kelch_2 PF07646.15 CBY14676.1 - 0.0035 17.3 0.7 3.5 7.8 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY14676.1 - 0.01 16.1 3.7 0.65 10.4 0.0 3.5 2 1 1 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY14676.1 - 0.7 9.9 2.7 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Lectin_C PF00059.21 CBY14677.1 - 3.8e-12 46.9 0.1 3.8e-12 46.9 0.1 2.5 3 0 0 3 3 3 2 Lectin C-type domain Trefoil PF00088.18 CBY14677.1 - 0.0052 16.6 4.9 0.015 15.1 4.9 1.8 1 0 0 1 1 1 1 Trefoil (P-type) domain Phage_integrase PF00589.22 CBY14678.1 - 0.012 15.4 0.3 0.022 14.5 0.1 1.5 2 0 0 2 2 2 0 Phage integrase family GPR15L PF15854.5 CBY14679.1 - 0.071 13.4 0.2 0.079 13.2 0.2 1.1 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Bax1-I PF01027.20 CBY14681.1 - 1.1e-29 103.8 15.8 1.4e-29 103.4 15.8 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2371 PF10177.9 CBY14681.1 - 0.11 12.6 1.0 19 5.4 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) RNA_pol_Rpb1_R PF05001.13 CBY14681.1 - 1.4 9.4 6.0 0.67 10.4 2.5 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat Bax1-I PF01027.20 CBY14682.1 - 7.2e-18 65.2 3.8 7.9e-18 65.0 3.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Peptidase_U4 PF03419.13 CBY14682.1 - 0.11 11.8 3.0 0.11 11.7 3.0 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA RNA_pol_Rpb1_R PF05001.13 CBY14682.1 - 0.13 12.7 2.5 0.23 11.9 2.5 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat DUF1412 PF07203.11 CBY14682.1 - 1.6 9.0 5.0 17 5.7 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1412) Kelch_4 PF13418.6 CBY14684.1 - 0.00055 19.9 2.4 0.26 11.3 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY14684.1 - 0.0031 17.5 7.9 0.016 15.2 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY14684.1 - 0.004 17.4 1.9 1.3 9.5 0.0 3.4 2 1 1 3 3 3 1 Kelch motif YabA PF06156.13 CBY14684.1 - 0.023 15.3 6.3 0.27 11.9 1.2 2.3 1 1 1 2 2 2 0 Initiation control protein YabA APC_N_CC PF16689.5 CBY14684.1 - 0.076 13.1 0.7 0.076 13.1 0.7 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Kelch_2 PF07646.15 CBY14684.1 - 0.11 12.5 0.4 0.96 9.5 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Herpes_BLRF2 PF05812.12 CBY14684.1 - 0.82 9.8 4.0 0.22 11.6 0.6 1.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein HALZ PF02183.18 CBY14684.1 - 3.5 7.9 6.0 2.7 8.3 0.3 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4407 PF14362.6 CBY14685.1 - 0.054 12.8 4.4 0.11 11.8 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spem1 PF15670.5 CBY14685.1 - 0.46 10.0 4.7 0.27 10.8 0.1 2.3 2 0 0 2 2 2 0 Spermatid maturation protein 1 FlxA PF14282.6 CBY14685.1 - 1.1 9.3 22.0 0.54 10.3 15.3 2.6 1 1 1 2 2 2 0 FlxA-like protein WBP-1 PF11669.8 CBY14685.1 - 1.9 9.1 0.0 1.9 9.1 0.0 2.9 3 1 1 4 4 4 0 WW domain-binding protein 1 Exonuc_VII_L PF02601.15 CBY14685.1 - 8.7 5.8 9.1 16 5.0 9.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 CBY14686.1 - 5.5e-07 29.9 2.1 9.2e-07 29.2 2.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Kelch_5 PF13854.6 CBY14686.1 - 0.00043 20.2 0.0 0.031 14.3 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Leu_zip PF15294.6 CBY14686.1 - 0.0047 16.5 2.5 0.0074 15.8 2.5 1.3 1 0 0 1 1 1 1 Leucine zipper Kelch_6 PF13964.6 CBY14686.1 - 0.018 15.3 0.2 1.8 9.0 0.0 3.4 3 1 1 4 4 4 0 Kelch motif PFU PF09070.11 CBY14686.1 - 0.046 14.0 0.3 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) YabA PF06156.13 CBY14686.1 - 0.11 13.1 8.9 1.1 10.0 2.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF2681 PF10883.8 CBY14686.1 - 0.14 12.6 2.7 0.4 11.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Kelch_4 PF13418.6 CBY14686.1 - 0.16 12.0 0.3 20 5.3 0.2 2.8 2 1 0 2 2 2 0 Galactose oxidase, central domain Ntox1 PF15500.6 CBY14686.1 - 0.23 11.8 0.5 0.48 10.8 0.5 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 SHE3 PF17078.5 CBY14686.1 - 0.23 11.2 9.8 0.46 10.2 9.5 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 ZapB PF06005.12 CBY14686.1 - 0.38 11.2 11.5 1.1 9.8 3.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB APC_N_CC PF16689.5 CBY14686.1 - 1.3 9.1 4.9 0.28 11.3 0.7 2.1 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Cep57_CLD_2 PF14197.6 CBY14686.1 - 1.5 8.9 16.3 1 9.5 8.3 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 SIKE PF05769.11 CBY14686.1 - 5.8 6.8 11.0 12 5.8 5.7 2.3 1 1 1 2 2 2 0 SIKE family Csm1_N PF18504.1 CBY14686.1 - 5.9 7.3 8.9 0.34 11.3 3.4 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain Kelch_5 PF13854.6 CBY14687.1 - 0.024 14.6 0.4 0.058 13.4 0.0 1.7 2 0 0 2 2 2 0 Kelch motif PFU PF09070.11 CBY14687.1 - 0.06 13.6 0.1 0.078 13.2 0.1 1.2 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) GH114_assoc PF14741.6 CBY14687.1 - 0.11 12.7 0.6 0.18 12.0 0.6 1.3 1 1 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Glyco_tranf_2_3 PF13641.6 CBY14688.1 - 3.8e-21 76.0 0.1 6.4e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_6 PF01341.17 CBY14688.1 - 1.9e-16 60.7 0.1 4.3e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Glyco_trans_2_3 PF13632.6 CBY14688.1 - 2.2e-15 57.1 2.8 2.2e-15 57.1 2.8 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CBY14688.1 - 4e-14 52.8 0.1 7e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 CBY14688.1 - 1.6e-07 30.2 12.5 5.2e-06 25.3 8.7 2.6 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 CBY14688.1 - 1.7e-07 30.9 0.0 3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 ZapB PF06005.12 CBY14690.1 - 0.02 15.3 2.4 0.036 14.5 2.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 CBY14690.1 - 0.028 14.5 2.2 0.054 13.6 1.5 1.8 1 1 1 2 2 2 0 bZIP transcription factor YabA PF06156.13 CBY14690.1 - 0.029 15.0 2.6 0.05 14.2 2.6 1.4 1 1 0 1 1 1 0 Initiation control protein YabA NRBF2 PF08961.10 CBY14690.1 - 0.03 13.9 2.2 0.042 13.5 2.0 1.4 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator PCRF PF03462.18 CBY14690.1 - 0.064 13.1 2.4 0.082 12.8 2.4 1.2 1 0 0 1 1 1 0 PCRF domain bZIP_2 PF07716.15 CBY14690.1 - 0.084 13.0 2.0 0.12 12.5 1.5 1.5 1 1 0 1 1 1 0 Basic region leucine zipper PCI PF01399.27 CBY14692.1 - 5.9e-13 49.2 3.4 6.2e-13 49.2 0.7 2.4 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 CBY14692.1 - 0.0042 16.8 0.4 0.014 15.1 0.4 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 CBY14692.1 - 0.07 13.6 0.1 0.69 10.5 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat CSN4_RPN5_eIF3a PF18420.1 CBY14692.1 - 0.13 12.5 2.0 0.21 11.8 0.4 2.2 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain FNIP_M PF14637.6 CBY14692.1 - 2.1 8.3 7.3 37 4.2 0.0 3.6 3 1 1 4 4 4 0 Folliculin-interacting protein middle domain JmjC PF02373.22 CBY14693.1 - 8.3e-39 132.5 0.6 1.9e-38 131.4 0.6 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.11 CBY14693.1 - 5.3e-22 78.4 14.4 3.9e-13 49.3 2.8 3.5 2 1 1 3 3 3 3 PLU-1-like protein JmjN PF02375.17 CBY14693.1 - 6.8e-16 57.9 2.5 7.3e-16 57.8 0.8 2.1 2 0 0 2 2 2 1 jmjN domain ARID PF01388.21 CBY14693.1 - 1.1e-15 58.1 0.0 2.4e-13 50.6 0.0 2.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 CBY14693.1 - 4.3e-09 36.1 35.9 2e-06 27.6 8.1 3.9 3 0 0 3 3 3 2 PHD-finger Remorin_C PF03763.13 CBY14693.1 - 0.0058 16.5 0.1 0.0058 16.5 0.1 2.8 3 0 0 3 3 3 1 Remorin, C-terminal region Laminin_I PF06008.14 CBY14693.1 - 3.9 7.1 7.4 77 2.9 7.4 2.7 1 1 0 1 1 1 0 Laminin Domain I Bac_RepA_C PF18008.1 CBY14693.1 - 8.1 6.9 8.7 6.5 7.2 0.4 3.4 3 0 0 3 3 3 0 Replication initiator protein A C-terminal domain Cation_ATPase_C PF00689.21 CBY14695.1 - 7.7e-41 139.8 5.1 1.4e-40 138.9 5.1 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CBY14695.1 - 4.9e-22 77.8 1.1 9.3e-22 76.9 0.5 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY14695.1 - 3.1e-21 76.6 0.8 4.4e-20 72.9 0.8 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CBY14695.1 - 3.8e-18 65.6 0.5 8.3e-18 64.5 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBY14695.1 - 2.6e-08 33.9 2.6 1.8e-07 31.2 1.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY14695.1 - 4.4e-05 24.0 0.0 0.00064 20.2 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Kelch_2 PF07646.15 CBY14696.1 - 0.0013 18.6 0.5 0.18 11.9 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY14696.1 - 0.0051 17.1 1.9 0.22 11.9 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY14696.1 - 0.046 13.7 6.0 0.67 10.0 0.1 3.3 4 0 0 4 4 4 0 Galactose oxidase, central domain ADH_zinc_N PF00107.26 CBY14697.1 - 6.9e-12 45.5 0.0 1.6e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBY14697.1 - 7.9e-09 35.4 0.5 5.5e-08 32.7 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CBY14697.1 - 1.9e-07 32.2 0.0 3.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zona_pellucida PF00100.23 CBY14698.1 - 4.9e-08 33.1 0.0 6.1e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain WH1 PF00568.23 CBY14700.1 - 0.059 13.3 0.1 0.089 12.7 0.1 1.2 1 0 0 1 1 1 0 WH1 domain Trypsin PF00089.26 CBY14701.1 - 3.3e-44 151.3 3.8 3.7e-44 151.2 3.8 1.0 1 0 0 1 1 1 1 Trypsin zf-RING_5 PF14634.6 CBY14702.1 - 5.7e-09 35.8 11.2 5.7e-09 35.8 11.2 3.5 3 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY14702.1 - 1.9e-07 30.8 22.0 5.8e-07 29.3 10.0 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY14702.1 - 5.5e-06 26.6 11.5 5.5e-06 26.6 11.5 2.9 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY14702.1 - 2.1e-05 24.5 16.2 0.0003 20.7 5.0 3.9 3 1 0 3 3 3 1 RING-type zinc-finger Rtf2 PF04641.12 CBY14702.1 - 2.1e-05 24.0 6.4 2.1e-05 24.0 6.4 2.7 1 1 1 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 CBY14702.1 - 0.00015 21.6 8.6 0.00015 21.6 8.6 3.6 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY14702.1 - 0.0012 18.6 9.4 0.0012 18.6 9.4 2.7 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY14702.1 - 0.0024 17.7 12.4 0.0024 17.7 12.4 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY14702.1 - 0.0025 17.5 12.0 0.0025 17.5 12.0 2.9 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 CBY14702.1 - 0.0086 16.0 6.0 0.0086 16.0 6.0 3.1 1 1 1 3 3 3 1 Baculovirus immediate-early protein (IE-0) C1_2 PF03107.16 CBY14702.1 - 0.026 14.8 21.6 0.037 14.4 2.0 4.0 4 0 0 4 4 4 0 C1 domain DUF2256 PF10013.9 CBY14702.1 - 0.076 13.1 0.3 0.076 13.1 0.3 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_11 PF17123.5 CBY14702.1 - 0.65 9.8 10.1 0.33 10.7 1.0 3.7 3 0 0 3 3 3 0 RING-like zinc finger Occludin_ELL PF07303.13 CBY14702.1 - 0.69 10.7 8.5 0.27 12.0 5.9 1.6 2 0 0 2 2 1 0 Occludin homology domain Evr1_Alr PF04777.13 CBY14702.1 - 2.5 8.6 14.0 0.051 14.0 4.2 2.7 1 1 0 2 2 2 0 Erv1 / Alr family Innexin PF00876.18 CBY14703.1 - 0.00072 19.0 0.1 0.00088 18.7 0.1 1.2 1 0 0 1 1 1 1 Innexin WW_like PF17890.1 CBY14703.1 - 0.12 12.5 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain Ion_trans PF00520.31 CBY14705.1 - 2.2e-21 76.2 23.0 2.9e-21 75.8 23.0 1.2 1 0 0 1 1 1 1 Ion transport protein ODV-E18 PF10717.9 CBY14705.1 - 0.28 11.1 5.2 0.87 9.5 0.0 3.1 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Lipocalin_2 PF08212.12 CBY14706.1 - 1.8e-14 53.9 0.2 2.1e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY14706.1 - 9.7e-10 38.8 0.1 1.1e-09 38.6 0.1 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family OPT PF03169.15 CBY14707.1 - 0.026 13.2 0.0 0.029 13.0 0.0 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein HEAT PF02985.22 CBY14708.1 - 0.0093 16.2 2.1 14 6.3 0.1 4.0 3 0 0 3 3 3 1 HEAT repeat MOR2-PAG1_N PF14222.6 CBY14708.1 - 0.025 13.6 0.7 0.096 11.6 0.7 1.8 1 1 0 1 1 1 0 Cell morphogenesis N-terminal AAA_16 PF13191.6 CBY14708.1 - 0.025 14.9 1.2 0.075 13.4 0.3 2.1 1 1 1 2 2 2 0 AAA ATPase domain V-ATPase_H_N PF03224.14 CBY14708.1 - 0.084 12.1 0.5 3.6 6.8 0.1 2.0 1 1 1 2 2 2 0 V-ATPase subunit H RVT_1 PF00078.27 CBY14710.1 - 5.3e-26 91.5 0.0 1.2e-25 90.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rib_recp_KP_reg PF05104.12 CBY14711.1 - 0.086 13.9 3.5 0.16 13.0 3.5 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region bZIP_2 PF07716.15 CBY14713.1 - 7.5e-15 54.8 10.9 1.5e-14 53.8 10.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY14713.1 - 8.9e-06 25.7 11.0 1.6e-05 24.9 11.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor Alpha-mann_mid PF09261.11 CBY14713.1 - 0.0059 16.7 0.9 0.01 16.0 0.5 1.7 1 1 0 1 1 1 1 Alpha mannosidase middle domain NAM-associated PF14303.6 CBY14713.1 - 0.0074 17.0 10.6 0.0074 17.0 10.6 1.7 1 1 1 2 2 2 1 No apical meristem-associated C-terminal domain FXR_C1 PF16096.5 CBY14713.1 - 0.017 15.3 0.3 0.017 15.3 0.3 2.5 2 1 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 EB1_binding PF05937.11 CBY14713.1 - 0.058 14.0 8.2 0.072 13.7 7.0 1.7 1 1 0 1 1 1 0 EB-1 Binding Domain bZIP_Maf PF03131.17 CBY14713.1 - 0.14 12.7 9.6 0.57 10.7 9.2 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor PIG-X PF08320.12 CBY14715.1 - 0.1 12.5 0.1 0.55 10.1 0.1 2.1 1 1 1 2 2 2 0 PIG-X / PBN1 COX14 PF14880.6 CBY14716.1 - 0.0071 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly TMEMspv1-c74-12 PF11044.8 CBY14716.1 - 0.044 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Pro-kuma_activ PF09286.11 CBY14717.1 - 1.6e-18 67.3 0.0 2.4e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF4064 PF13273.6 CBY14718.1 - 0.011 16.0 0.1 0.011 16.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) GH101_N PF17995.1 CBY14718.1 - 0.25 11.0 0.8 4.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Endo-alpha-N-acetylgalactosaminidase N-terminal Collagen PF01391.18 CBY14719.1 - 3.6e-69 228.4 272.5 1e-08 34.8 27.2 10.2 2 1 7 9 9 9 8 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY14719.1 - 1.1e-27 97.5 0.0 2.7e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY14719.1 - 0.00034 21.2 0.0 0.00059 20.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Collagen PF01391.18 CBY14721.1 - 7.3e-119 387.6 427.9 6.2e-09 35.5 26.0 17.5 5 3 11 16 16 16 15 Collagen triple helix repeat (20 copies) C4 PF01413.19 CBY14721.1 - 6.4e-36 123.1 7.2 4e-17 62.6 3.8 3.1 2 1 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen COX4 PF02936.14 CBY14722.1 - 1.4e-12 47.8 0.5 4.7e-12 46.1 0.5 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit IV HMG_box_2 PF09011.10 CBY14722.1 - 0.0062 17.1 0.2 0.1 13.2 0.0 2.2 2 0 0 2 2 2 1 HMG-box domain SQHop_cyclase_N PF13249.6 CBY14722.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain AAR2 PF05282.11 CBY14724.1 - 1.1e-41 143.4 0.9 1.3e-41 143.2 0.9 1.0 1 0 0 1 1 1 1 AAR2 protein AAR2 PF05282.11 CBY14725.1 - 2.1e-19 70.2 0.0 2.4e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein FAST_2 PF08368.12 CBY14726.1 - 0.033 15.0 0.2 0.099 13.4 0.2 1.9 1 1 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Sulfotransfer_1 PF00685.27 CBY14729.1 - 1.8e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY14729.1 - 0.0011 19.4 0.0 3.9 7.8 0.0 3.1 2 1 1 3 3 3 3 Sulfotransferase family DHODB_Fe-S_bind PF10418.9 CBY14732.1 - 0.007 16.1 5.2 1.2 9.0 0.1 4.2 4 0 0 4 4 4 3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Solute_trans_a PF03619.16 CBY14733.1 - 1.2e-21 77.5 20.4 1.6e-21 77.1 20.4 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SBF_like PF13593.6 CBY14734.1 - 3e-76 256.7 21.3 3.8e-76 256.4 21.3 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CBY14734.1 - 3.5e-16 59.5 12.3 3.5e-16 59.5 12.3 2.0 3 1 0 3 3 3 1 Sodium Bile acid symporter family NnrS PF05940.12 CBY14734.1 - 0.015 14.7 10.8 0.0078 15.6 8.2 1.8 1 1 0 1 1 1 0 NnrS protein DnaJ PF00226.31 CBY14735.1 - 7e-06 26.1 1.0 0.095 12.8 0.0 2.9 2 1 1 3 3 3 2 DnaJ domain Geminin PF07412.12 CBY14735.1 - 5.4e-05 23.0 4.3 5.4e-05 23.0 4.3 1.5 2 0 0 2 2 2 1 Geminin RPN7 PF10602.9 CBY14735.1 - 0.84 9.3 4.6 2.2 8.0 4.6 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Lectin_C PF00059.21 CBY14736.1 - 0.0028 18.3 0.8 0.0061 17.3 0.8 1.6 1 0 0 1 1 1 1 Lectin C-type domain zf-FLZ PF04570.14 CBY14736.1 - 0.13 11.7 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Thioredoxin PF00085.20 CBY14738.1 - 5.2e-63 209.5 0.1 1.5e-28 98.8 0.0 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 CBY14738.1 - 7.6e-42 143.3 0.1 8.7e-33 113.8 0.3 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY14738.1 - 1.8e-12 47.4 0.0 0.00024 21.4 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 CBY14738.1 - 2.8e-09 36.7 0.0 0.0097 15.3 0.0 3.1 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBY14738.1 - 4.8e-08 33.4 2.3 0.029 14.8 0.0 4.4 3 3 2 5 5 5 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY14738.1 - 6.6e-08 32.5 0.1 0.00043 20.2 0.0 3.3 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 CBY14738.1 - 3.9e-07 29.9 1.4 0.14 11.9 0.0 3.5 2 1 1 3 3 3 2 Redoxin Thioredoxin_7 PF13899.6 CBY14738.1 - 2.6e-06 27.5 0.1 0.13 12.4 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like ERp29_N PF07912.13 CBY14738.1 - 0.0003 20.9 0.2 3.6 7.7 0.0 4.0 3 1 1 4 4 4 1 ERp29, N-terminal domain TraF PF13728.6 CBY14738.1 - 0.032 14.0 0.0 4.1 7.2 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 CBY14738.1 - 0.43 10.8 2.0 9.4 6.5 0.0 3.5 4 0 0 4 4 4 0 Glutaredoxin Sulfotransfer_1 PF00685.27 CBY14739.1 - 7.7e-05 22.3 1.9 0.00083 18.9 1.9 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY14739.1 - 0.0067 16.8 0.1 0.02 15.3 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 CBY14740.1 - 2.3e-39 135.5 1.2 3.1e-39 135.0 1.2 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY14740.1 - 0.0068 16.8 0.1 0.014 15.8 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family MPLKIP PF15502.6 CBY14743.1 - 4.2e-08 33.3 0.0 4.2e-08 33.3 0.0 3.0 3 1 0 3 3 3 1 M-phase-specific PLK1-interacting protein MPLKIP PF15502.6 CBY14744.1 - 9.4e-16 57.8 0.2 9.4e-16 57.8 0.2 2.0 2 0 0 2 2 2 1 M-phase-specific PLK1-interacting protein NAM-associated PF14303.6 CBY14744.1 - 0.2 12.4 5.1 0.31 11.7 5.1 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RR_TM4-6 PF06459.12 CBY14744.1 - 1.3 8.8 5.1 1.7 8.4 5.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 CBY14744.1 - 2.7 7.3 12.9 3.4 7.0 12.9 1.1 1 0 0 1 1 1 0 SDA1 AAA_18 PF13238.6 CBY14745.1 - 3.7e-28 98.7 0.0 5.8e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBY14745.1 - 7.5e-07 29.4 0.1 0.0003 21.0 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CBY14745.1 - 6.3e-06 26.7 0.3 0.00031 21.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 CBY14745.1 - 3.3e-05 23.8 1.9 0.16 11.8 0.1 2.1 1 1 0 2 2 2 2 Deoxynucleoside kinase MeaB PF03308.16 CBY14745.1 - 0.00026 20.1 0.4 0.017 14.1 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CBY14745.1 - 0.00029 21.4 0.0 0.00034 21.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter KTI12 PF08433.10 CBY14745.1 - 0.0014 18.1 0.1 0.0049 16.3 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 CBY14745.1 - 0.0015 18.6 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY14745.1 - 0.0018 18.7 0.0 0.002 18.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 CBY14745.1 - 0.0019 18.1 0.1 0.0043 17.0 0.0 1.7 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.6 CBY14745.1 - 0.0024 18.1 0.0 0.0064 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBY14745.1 - 0.0025 18.1 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CBY14745.1 - 0.0026 18.2 0.3 0.0064 16.9 0.3 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 CBY14745.1 - 0.0034 16.8 0.1 0.0071 15.7 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CBY14745.1 - 0.0056 16.8 0.1 0.022 14.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ADK PF00406.22 CBY14745.1 - 0.0063 16.6 0.1 0.091 12.9 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase RNA_helicase PF00910.22 CBY14745.1 - 0.0095 16.3 0.1 0.035 14.5 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Hpr_kinase_C PF07475.12 CBY14745.1 - 0.01 15.3 0.1 0.017 14.7 0.1 1.3 1 1 0 1 1 1 0 HPr Serine kinase C-terminal domain Rad17 PF03215.15 CBY14745.1 - 0.014 15.3 0.1 0.056 13.4 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain SKI PF01202.22 CBY14745.1 - 0.016 15.3 1.9 8.6 6.5 0.3 2.9 2 1 1 3 3 3 0 Shikimate kinase RsgA_GTPase PF03193.16 CBY14745.1 - 0.017 15.1 0.3 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 CBY14745.1 - 0.024 14.1 0.1 0.051 13.1 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CBY14745.1 - 0.041 13.7 0.8 0.28 10.9 0.2 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 CBY14745.1 - 0.07 12.3 0.1 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.14 CBY14745.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 CBY14745.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CBY14745.1 - 0.093 12.5 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase AAA_29 PF13555.6 CBY14745.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CBY14745.1 - 0.14 11.6 0.1 0.38 10.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 CBY14745.1 - 0.15 12.4 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain RepB PF07506.11 CBY14745.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 RepB plasmid partitioning protein SNARE PF05739.19 CBY14746.1 - 8.8e-09 35.2 2.2 1.1e-08 34.9 0.2 2.2 2 0 0 2 2 2 1 SNARE domain DUF948 PF06103.11 CBY14746.1 - 0.0006 20.0 9.6 0.037 14.3 0.3 2.6 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 CBY14746.1 - 1.7 8.7 15.5 0.48 10.4 3.4 3.0 2 1 1 3 3 3 0 Laminin Domain II Nup54 PF13874.6 CBY14746.1 - 3 8.0 14.1 0.79 9.8 0.5 3.1 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 YabA PF06156.13 CBY14746.1 - 6.9 7.4 9.8 1.5 9.5 0.5 2.6 1 1 0 2 2 2 0 Initiation control protein YabA SHS2_Rpb7-N PF03876.17 CBY14747.1 - 3.7e-06 27.2 0.0 5.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MTP18 PF10558.9 CBY14748.1 - 4.2e-14 52.9 2.8 4.3e-08 33.3 0.3 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) DUF5082 PF16888.5 CBY14749.1 - 0.0076 16.5 7.0 0.17 12.2 2.4 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) SH3BP5 PF05276.14 CBY14749.1 - 0.0081 16.0 4.0 0.01 15.7 4.0 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Phage_TAC_7 PF10109.9 CBY14749.1 - 0.076 13.1 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 TMPIT PF07851.13 CBY14749.1 - 0.4 9.9 6.9 0.43 9.8 6.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 CBY14749.1 - 1.9 8.6 8.6 2.3 8.4 8.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Op_neuropeptide PF08035.11 CBY14750.1 - 0.12 12.3 4.6 0.36 10.7 0.9 2.4 2 0 0 2 2 2 0 Opioids neuropeptide Clathrin_lg_ch PF01086.17 CBY14751.1 - 4.4e-33 115.3 5.1 5e-33 115.1 5.1 1.0 1 0 0 1 1 1 1 Clathrin light chain Unstab_antitox PF09720.10 CBY14751.1 - 0.31 11.1 3.9 1.4 9.1 0.3 2.5 1 1 1 2 2 2 0 Putative addiction module component DUF4690 PF15756.5 CBY14752.1 - 0.019 15.5 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage FAM176 PF14851.6 CBY14752.1 - 0.043 13.5 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Clathrin_lg_ch PF01086.17 CBY14753.1 - 4.3e-43 148.0 7.3 5e-43 147.8 7.3 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF4690 PF15756.5 CBY14754.1 - 0.013 16.1 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage FAM176 PF14851.6 CBY14754.1 - 0.042 13.5 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 FAM176 family ABC_tran PF00005.27 CBY14755.1 - 5.4e-49 166.2 7.8 1.1e-27 97.2 0.0 3.5 4 0 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 CBY14755.1 - 3.8e-13 49.9 8.1 0.0015 18.4 0.1 4.8 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 CBY14755.1 - 4.7e-08 32.9 12.1 4.7e-08 32.9 12.1 3.6 3 0 0 3 3 2 1 ABC transporter AAA_29 PF13555.6 CBY14755.1 - 6.4e-06 25.8 0.1 0.029 14.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBY14755.1 - 1.1e-05 25.4 0.0 0.017 15.1 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CBY14755.1 - 2.8e-05 24.6 0.1 0.071 13.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBY14755.1 - 5.5e-05 23.5 0.0 0.35 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CBY14755.1 - 0.0001 22.3 0.1 0.042 13.9 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_14 PF13173.6 CBY14755.1 - 0.00013 22.0 0.3 0.62 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 CBY14755.1 - 0.00016 21.4 4.5 0.36 10.5 0.0 3.8 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 CBY14755.1 - 0.00019 21.4 0.0 0.78 9.6 0.0 2.4 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 CBY14755.1 - 0.00034 21.0 0.3 1.2 9.6 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.6 CBY14755.1 - 0.00036 20.7 1.0 0.74 10.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 CBY14755.1 - 0.00072 20.0 0.0 1.5 9.3 0.0 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBY14755.1 - 0.00076 20.0 1.1 0.34 11.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CBY14755.1 - 0.00098 19.4 1.7 0.3 11.3 0.0 3.4 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 CBY14755.1 - 0.0046 16.2 0.0 3.6 6.7 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain NTPase_1 PF03266.15 CBY14755.1 - 0.0058 16.6 0.1 5.6 6.8 0.0 2.9 2 0 0 2 2 2 2 NTPase Roc PF08477.13 CBY14755.1 - 0.0073 16.5 0.1 3.4 7.9 0.0 3.2 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CBY14755.1 - 0.013 15.1 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CBY14755.1 - 0.014 15.9 0.1 0.24 11.9 0.0 5.6 4 1 0 4 4 3 0 AAA domain AAA_30 PF13604.6 CBY14755.1 - 0.052 13.3 3.6 6.4 6.4 0.0 3.2 3 1 1 4 4 3 0 AAA domain CLP1_P PF16575.5 CBY14755.1 - 0.058 13.2 1.2 8.7 6.1 0.0 3.0 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 CBY14755.1 - 0.058 13.4 0.4 6.3 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY14755.1 - 0.078 12.5 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 CBY14755.1 - 0.17 11.9 0.0 0.17 11.9 0.0 4.3 5 1 0 5 5 4 0 Dynamin family SPESP1 PF15754.5 CBY14755.1 - 1.8 7.7 11.9 0.073 12.2 5.3 2.1 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 AAA PF00004.29 CBY14756.1 - 3.1e-40 137.6 0.0 8e-40 136.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CBY14756.1 - 6.6e-13 48.4 0.2 7.8e-12 45.0 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CBY14756.1 - 2.2e-09 36.9 0.1 2.7e-08 33.5 0.1 2.7 1 1 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CBY14756.1 - 3.5e-05 23.6 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBY14756.1 - 0.00018 21.7 0.0 0.00051 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CBY14756.1 - 0.00032 20.8 0.0 0.00096 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CBY14756.1 - 0.00073 18.8 0.0 0.0023 17.2 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 CBY14756.1 - 0.0022 18.0 0.1 0.019 14.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY14756.1 - 0.0023 18.4 0.0 0.0064 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY14756.1 - 0.0032 17.8 0.1 0.11 12.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 CBY14756.1 - 0.0034 17.4 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CBY14756.1 - 0.0055 16.1 0.3 0.017 14.5 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBY14756.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CBY14756.1 - 0.017 15.1 0.0 0.056 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 CBY14756.1 - 0.018 13.6 1.0 0.023 13.3 1.0 1.2 1 0 0 1 1 1 0 Macoilin family AAA_7 PF12775.7 CBY14756.1 - 0.025 14.1 0.2 0.11 12.0 0.1 2.0 1 1 1 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBY14756.1 - 0.029 14.7 0.0 0.094 13.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CBY14756.1 - 0.042 14.4 0.9 0.24 11.9 0.9 2.3 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CBY14756.1 - 0.045 13.1 0.0 1.8 7.9 0.1 2.6 1 1 1 2 2 2 0 KaiC Ndc1_Nup PF09531.10 CBY14756.1 - 0.064 11.9 3.9 0.082 11.6 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PhoH PF02562.16 CBY14756.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CBY14756.1 - 0.1 12.3 0.0 0.53 10.0 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 CBY14756.1 - 0.13 12.2 0.1 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 CBY14756.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CBY14756.1 - 0.16 11.2 1.2 0.16 11.2 0.1 1.6 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CBY14756.1 - 0.52 10.1 8.3 0.12 12.1 0.5 2.6 2 1 0 2 2 2 0 AAA domain Cytochrom_B562 PF07361.11 CBY14756.1 - 0.67 10.6 3.1 0.83 10.3 0.1 2.6 3 0 0 3 3 2 0 Cytochrome b562 Shugoshin_N PF07558.11 CBY14759.1 - 0.014 15.3 9.2 0.016 15.1 0.2 4.0 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region GIT_CC PF16559.5 CBY14759.1 - 0.036 13.9 1.0 0.036 13.9 1.0 5.9 6 1 1 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2423 PF10338.9 CBY14759.1 - 2 8.7 5.0 3.3 8.0 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2423) zf-RING_5 PF14634.6 CBY14761.1 - 5e-08 32.8 9.5 5e-08 32.8 9.5 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY14761.1 - 1.5e-07 31.3 2.7 4e-07 30.0 2.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY14761.1 - 4.9e-07 29.5 9.2 1.1e-06 28.4 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY14761.1 - 2.9e-06 27.5 10.5 5.8e-06 26.5 10.5 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBY14761.1 - 8.9e-06 25.5 8.3 8.9e-06 25.5 8.3 2.0 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY14761.1 - 1.3e-05 25.0 10.0 2.9e-05 23.8 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY14761.1 - 0.00011 22.0 7.5 0.00011 22.0 7.5 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CBY14761.1 - 0.00013 21.4 5.8 0.00021 20.8 5.8 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.6 CBY14761.1 - 0.00015 21.5 10.1 0.00032 20.4 10.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CBY14761.1 - 0.036 13.9 1.2 0.069 13.0 1.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 CBY14761.1 - 0.041 13.6 4.5 0.098 12.4 4.5 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBY14761.1 - 0.8 9.9 9.4 15 5.8 10.1 2.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-4CXXC_R1 PF10497.9 CBY14761.1 - 1.8 8.8 10.8 1.7 8.9 8.3 2.2 2 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF1272 PF06906.11 CBY14761.1 - 2.3 8.4 11.0 0.099 12.7 5.6 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) HypA PF01155.19 CBY14761.1 - 5.4 7.1 8.0 22 5.1 8.0 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3079 PF11278.8 CBY14762.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3079) Neur_chan_memb PF02932.16 CBY14764.1 - 2.1e-24 86.9 7.1 2.5e-24 86.7 7.1 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Utp21 PF04192.12 CBY14765.1 - 0.18 11.3 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Pox_int_trans PF05718.12 CBY14767.1 - 0.095 11.4 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor Kelch_6 PF13964.6 CBY14768.1 - 0.014 15.7 2.8 11 6.4 0.1 3.4 2 1 1 3 3 3 0 Kelch motif ABM PF03992.16 CBY14769.1 - 0.012 15.7 2.2 4.1 7.6 0.2 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase MYT1 PF08474.11 CBY14769.1 - 0.056 13.4 6.4 2.1 8.2 0.6 2.1 2 0 0 2 2 2 0 Myelin transcription factor 1 DUF2564 PF10819.8 CBY14769.1 - 0.13 12.7 0.6 24 5.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) SH3_9 PF14604.6 CBY14771.1 - 2.3e-15 56.2 1.1 3.5e-15 55.6 1.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY14771.1 - 8.1e-11 41.4 0.3 1.5e-10 40.5 0.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY14771.1 - 2.5e-08 33.5 0.0 3.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain tRNA_anti-codon PF01336.25 CBY14771.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Astacin PF01400.24 CBY14773.1 - 5.9e-46 156.5 0.1 1e-45 155.7 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) UPF0054 PF02130.17 CBY14773.1 - 0.067 13.0 0.7 0.13 12.1 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 DUF4304 PF14137.6 CBY14773.1 - 0.17 12.0 1.8 0.33 11.1 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4304) Ammonium_transp PF00909.21 CBY14774.1 - 8.1e-65 219.1 29.2 1.9e-64 217.9 29.2 1.6 1 1 0 1 1 1 1 Ammonium Transporter Family TssO PF17561.2 CBY14774.1 - 0.19 11.8 1.6 0.41 10.7 1.6 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO Lyase_1 PF00206.20 CBY14775.1 - 1.6e-55 188.7 0.0 1.1e-44 153.1 0.0 2.4 2 1 1 3 3 3 2 Lyase ASL_C2 PF14698.6 CBY14775.1 - 3e-09 37.5 0.0 6.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Ammonium_transp PF00909.21 CBY14776.1 - 2.2e-58 197.9 13.3 3.1e-58 197.4 13.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family PEMT PF04191.13 CBY14776.1 - 0.098 13.1 8.2 7.2 7.1 0.1 3.6 3 1 0 3 3 3 0 Phospholipid methyltransferase DUF1003 PF06210.11 CBY14776.1 - 0.12 12.5 0.4 0.12 12.5 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Cyclin_N PF00134.23 CBY14777.1 - 4.3e-18 65.3 0.1 2.6e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3456 PF11938.8 CBY14777.1 - 0.081 13.4 0.2 0.2 12.1 0.2 1.7 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Kelch_2 PF07646.15 CBY14778.1 - 0.0098 15.8 2.5 5.5 7.1 0.0 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.6 CBY14778.1 - 0.03 14.6 1.8 3.8 8.0 0.0 3.9 4 0 0 4 4 4 0 Kelch motif Nmad2 PF18753.1 CBY14778.1 - 0.06 12.8 0.0 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Nucleotide modification associated domain 2 PH_RBD PF12068.8 CBY14778.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Rab-binding domain (RBD) CCDC85 PF10226.9 CBY14778.1 - 0.11 12.1 0.4 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 CCDC85 family Kelch_5 PF13854.6 CBY14778.1 - 0.16 12.0 2.2 0.57 10.2 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 CBY14778.1 - 0.52 10.4 2.1 37 4.4 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF1043 PF06295.12 CBY14780.1 - 0.29 11.2 3.4 13 5.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Fumarate_red_D PF02313.17 CBY14782.1 - 0.79 9.9 5.9 0.95 9.6 2.5 2.1 1 1 1 2 2 2 0 Fumarate reductase subunit D HemY_N PF07219.13 CBY14782.1 - 9.7 6.4 6.0 1.5 9.1 0.5 2.0 1 1 1 2 2 2 0 HemY protein N-terminus Kelch_2 PF07646.15 CBY14786.1 - 0.00017 21.4 1.6 2.2 8.4 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY14786.1 - 0.1 12.6 4.8 0.33 11.0 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 CBY14786.1 - 0.39 11.1 2.6 6.8 7.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif MyTH4 PF00784.17 CBY14787.1 - 1.7e-18 67.1 0.5 4.8e-18 65.6 0.5 1.8 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 CBY14787.1 - 1.2e-09 38.6 0.1 1.5e-08 35.1 0.0 2.6 3 0 0 3 3 3 1 FERM central domain FERM_N PF09379.10 CBY14787.1 - 0.0014 18.5 0.0 0.0051 16.7 0.0 1.9 2 0 0 2 2 2 1 FERM N-terminal domain Kelch_2 PF07646.15 CBY14788.1 - 0.018 15.0 0.1 0.76 9.8 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.6 CBY14788.1 - 0.35 10.9 1.9 0.46 10.5 0.1 1.9 2 0 0 2 2 2 0 Kelch motif zf-C2H2 PF00096.26 CBY14794.1 - 2.5e-24 84.3 38.7 0.00013 22.2 0.1 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY14794.1 - 2.6e-19 68.7 47.2 8.2e-06 26.0 3.5 6.9 6 1 0 6 6 6 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY14794.1 - 2.7e-19 68.2 38.0 0.0033 18.1 0.1 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY14794.1 - 8.1e-11 41.6 35.8 0.0053 16.7 1.4 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY14794.1 - 1.2e-06 28.1 18.8 0.029 14.1 0.0 6.0 6 0 0 6 6 6 2 zinc-finger C2H2-type zf_UBZ PF18439.1 CBY14794.1 - 3.3e-06 26.6 19.9 0.86 9.3 0.2 6.6 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 CBY14794.1 - 1.5e-05 25.0 30.0 0.08 13.0 0.9 6.1 1 1 4 5 5 5 4 CpXC protein zf-C2H2_3rep PF18868.1 CBY14794.1 - 6.8e-05 23.5 22.7 0.037 14.7 7.4 4.6 2 1 3 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 CBY14794.1 - 0.00012 22.3 27.3 0.039 14.2 4.3 4.2 2 2 2 4 4 4 4 C2H2-type zinc ribbon ADK_lid PF05191.14 CBY14794.1 - 0.00017 21.5 18.4 0.4 10.7 2.1 4.7 4 1 0 4 4 4 3 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 CBY14794.1 - 0.0042 17.3 1.1 0.0042 17.3 1.1 6.8 7 0 0 7 7 6 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY14794.1 - 0.0065 16.8 1.3 0.0065 16.8 1.3 6.0 6 0 0 6 6 6 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CBY14794.1 - 0.03 14.4 31.8 2.5 8.3 0.6 6.3 6 0 0 6 6 6 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 CBY14794.1 - 0.04 13.8 0.5 0.04 13.8 0.5 6.6 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Sgf11 PF08209.11 CBY14794.1 - 0.25 10.9 17.7 0.62 9.7 0.1 5.7 6 0 0 6 6 6 0 Sgf11 (transcriptional regulation protein) HypA PF01155.19 CBY14794.1 - 0.3 11.1 25.7 2.3 8.3 1.2 4.6 2 2 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 CBY14794.1 - 0.77 10.0 38.3 5.1 7.3 1.1 6.4 6 0 0 6 6 6 0 AN1-like Zinc finger LIM PF00412.22 CBY14794.1 - 1.1 9.5 37.3 1.2 9.4 7.3 5.5 3 2 0 4 4 4 0 LIM domain Ta0938 PF11494.8 CBY14794.1 - 1.2 9.4 11.9 1.9 8.8 1.0 3.7 3 1 1 4 4 4 0 Ta0938 XPA_N PF01286.18 CBY14794.1 - 1.4 9.0 37.2 1.8 8.6 1.6 6.5 6 0 0 6 6 6 0 XPA protein N-terminal zf-3CxxC PF13695.6 CBY14794.1 - 2.8 8.5 33.4 0.48 10.9 3.0 5.0 4 2 1 5 5 5 0 Zinc-binding domain C1_4 PF07975.12 CBY14794.1 - 3.6 7.9 31.5 1.1 9.5 0.7 5.7 2 2 2 5 5 5 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 CBY14794.1 - 5.1 7.1 29.1 19 5.3 3.6 6.1 5 1 0 5 5 5 0 zinc-ribbon domain zf-H2C2_5 PF13909.6 CBY14794.1 - 5.9 6.7 19.1 7 6.5 0.0 4.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DUF4795 PF16043.5 CBY14795.1 - 4.7e-39 134.1 8.9 4.7e-39 134.1 8.9 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4795) SbsC_C PF18058.1 CBY14795.1 - 0.34 11.1 4.6 1 9.6 3.4 2.5 1 1 1 2 2 2 0 SbsC C-terminal domain LemA PF04011.12 CBY14795.1 - 0.54 10.1 6.1 9.7 6.0 0.4 3.6 3 0 0 3 3 3 0 LemA family DUF948 PF06103.11 CBY14795.1 - 1.8 8.9 12.0 10 6.5 0.2 5.2 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 CBY14795.1 - 6 4.7 11.9 0.55 8.1 5.7 2.0 2 0 0 2 2 2 0 Prominin DUF5383 PF17355.2 CBY14795.1 - 8.7 6.7 7.1 0.5 10.7 0.3 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5383) LRR_8 PF13855.6 CBY14797.1 - 1.2e-23 82.6 30.9 3.2e-10 39.6 3.2 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBY14797.1 - 2.3e-12 46.9 25.2 3.2e-05 24.2 3.4 5.0 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY14797.1 - 5.2e-11 42.6 4.8 5.1e-09 36.2 1.1 1.9 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 CBY14797.1 - 4.4e-06 26.3 12.8 0.19 11.8 0.1 5.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 CBY14797.1 - 2.1e-05 24.4 17.5 0.91 10.3 0.2 6.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 CBY14797.1 - 0.0046 16.5 6.4 0.0072 15.9 5.4 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBY14798.1 - 1e-16 60.4 0.9 5.6e-07 29.2 0.1 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBY14798.1 - 9.3e-12 45.0 0.9 8.9e-06 26.0 0.2 4.0 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY14798.1 - 5.8e-10 39.2 1.6 8.1e-10 38.7 1.6 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBY14798.1 - 0.0016 18.7 2.3 1.6 9.6 0.1 4.2 5 0 0 5 5 5 1 Leucine Rich Repeat YebF PF13995.6 CBY14798.1 - 0.087 12.8 0.0 7 6.7 0.0 2.5 2 0 0 2 2 2 0 YebF-like protein LRR_6 PF13516.6 CBY14798.1 - 0.11 12.6 0.5 8.6 6.7 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Branch PF02485.21 CBY14799.1 - 6.5e-42 143.7 0.0 8.2e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Phospholip_A2_1 PF00068.19 CBY14800.1 - 4.6e-14 52.8 10.8 5.8e-14 52.5 10.8 1.1 1 0 0 1 1 1 1 Phospholipase A2 zf-RING_5 PF14634.6 CBY14801.1 - 1.7e-06 27.9 11.7 1.7e-06 27.9 11.7 2.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY14801.1 - 1.2e-05 25.5 11.5 1.2e-05 25.5 11.5 2.4 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 CBY14801.1 - 6.1e-05 22.8 8.4 6.1e-05 22.8 8.4 3.0 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CBY14801.1 - 0.0012 18.7 8.8 0.0012 18.7 8.8 2.2 1 1 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 CBY14801.1 - 0.0021 17.9 9.0 0.0021 17.9 9.0 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBY14801.1 - 0.0078 16.2 5.6 0.0078 16.2 5.6 3.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY14801.1 - 0.012 15.4 10.7 0.012 15.4 10.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY14801.1 - 0.021 14.6 9.5 0.021 14.6 9.5 2.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain RPN6_N PF18055.1 CBY14801.1 - 0.027 14.8 2.5 0.05 14.0 2.5 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Rtf2 PF04641.12 CBY14801.1 - 0.15 11.4 14.3 0.099 12.0 11.2 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger Xpo1 PF08389.12 CBY14801.1 - 1.1 9.3 5.6 2.3 8.3 5.6 1.5 1 1 0 1 1 1 0 Exportin 1-like protein zf-C3HC4_4 PF15227.6 CBY14801.1 - 4.9 7.4 16.6 1.1e+02 3.1 14.8 3.9 2 1 2 4 4 4 0 zinc finger of C3HC4-type, RING Cas9_b_hairpin PF17893.1 CBY14802.1 - 0.1 12.4 0.0 7.5 6.4 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain Csm1_N PF18504.1 CBY14803.1 - 0.0044 17.3 0.1 0.0073 16.6 0.1 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain Ax_dynein_light PF10211.9 CBY14803.1 - 0.019 14.9 0.9 0.023 14.6 0.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4407 PF14362.6 CBY14803.1 - 0.033 13.5 0.2 0.033 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliD_C PF07195.12 CBY14803.1 - 0.038 13.4 0.1 0.05 13.0 0.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Med9 PF07544.13 CBY14803.1 - 0.091 12.9 0.5 0.16 12.1 0.5 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CCDC-167 PF15188.6 CBY14803.1 - 1.3 9.4 4.6 2.2 8.7 4.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 ATP-gua_Ptrans PF00217.19 CBY14804.1 - 1.6e-60 204.2 0.0 2.2e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY14804.1 - 8.6e-24 83.7 0.0 1.4e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Glyco_transf_7C PF02709.14 CBY14805.1 - 1.1e-24 85.9 0.0 1.3e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY14805.1 - 0.01 15.3 0.0 0.01 15.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pkinase PF00069.25 CBY14806.1 - 4.6e-45 154.0 0.3 4.6e-45 154.0 0.3 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14806.1 - 2.9e-29 102.2 0.1 5.5e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY14806.1 - 4.3e-05 22.5 0.5 0.00087 18.2 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBY14806.1 - 0.00054 19.5 0.1 0.00054 19.5 0.1 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kelch_2 PF07646.15 CBY14807.1 - 0.0073 16.2 0.4 4.4 7.4 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY14807.1 - 0.027 14.8 2.9 1.2 9.5 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 CBY14807.1 - 0.26 11.3 0.0 0.26 11.3 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Homeodomain PF00046.29 CBY14808.1 - 7.4e-22 77.0 1.7 7.4e-22 77.0 1.7 2.0 3 0 0 3 3 3 1 Homeodomain Homez PF11569.8 CBY14808.1 - 0.0029 17.1 0.2 0.0071 15.8 0.2 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 CBY14808.1 - 0.013 15.4 0.2 0.096 12.6 0.0 2.3 2 0 0 2 2 2 0 Homeobox KN domain RVT_1 PF00078.27 CBY14810.1 - 1.8e-16 60.4 0.2 4.1e-16 59.2 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY14810.1 - 1e-15 57.9 0.0 5.2e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 CBY14810.1 - 3.8e-08 33.6 0.0 2.8e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY14810.1 - 1.9e-06 27.9 0.0 5.5e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_A2B PF12384.8 CBY14810.1 - 0.00042 19.9 0.2 0.0012 18.4 0.2 1.7 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP PF00077.20 CBY14810.1 - 0.0024 18.1 0.0 0.0064 16.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CBY14810.1 - 0.0076 16.9 0.0 0.018 15.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY14810.1 - 0.036 14.6 0.0 0.088 13.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 CBY14810.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain MFS_1 PF07690.16 CBY14811.1 - 6.7e-13 48.3 3.3 7.3e-13 48.2 3.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CBY14811.1 - 0.00079 18.8 0.9 0.0011 18.3 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 CBY14811.1 - 0.0093 14.6 0.4 0.012 14.2 0.2 1.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like UL20 PF17582.2 CBY14811.1 - 0.033 13.5 0.1 0.05 12.9 0.1 1.3 1 1 0 1 1 1 0 Cytomegalovirus UL20 MscL PF01741.18 CBY14811.1 - 0.049 13.9 0.1 0.083 13.2 0.1 1.4 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL 7TMR-DISM_7TM PF07695.11 CBY14811.1 - 0.28 11.0 9.7 6 6.7 9.7 2.0 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF202 PF02656.15 CBY14811.1 - 0.98 9.9 5.0 5.1 7.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Methyltransf_31 PF13847.6 CBY14812.1 - 0.85 9.4 3.0 3.7 7.3 3.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Integrase_H2C2 PF17921.1 CBY14813.1 - 0.00094 19.2 0.1 0.00094 19.2 0.1 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain Co_AT_N PF12557.8 CBY14813.1 - 0.19 11.7 1.3 0.42 10.6 1.3 1.6 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal SpoIIIAH PF12685.7 CBY14814.1 - 5.6 6.7 9.5 1.4 8.7 5.8 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein Helicase_C PF00271.31 CBY14815.1 - 1.6e-12 47.8 0.0 8.6e-11 42.2 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY14815.1 - 4.6e-11 42.8 0.0 9.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CI-B14_5a PF07347.12 CBY14816.1 - 0.042 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) ISG65-75 PF11727.8 CBY14816.1 - 0.078 12.2 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF4263 PF14082.6 CBY14816.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Syntaxin-18_N PF10496.9 CBY14817.1 - 0.041 14.1 0.3 0.27 11.5 0.3 2.4 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF5601 PF18151.1 CBY14817.1 - 0.048 14.0 0.5 25 5.3 0.0 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF5601) HP0268 PF18618.1 CBY14817.1 - 0.1 13.0 1.6 0.22 12.0 0.4 2.1 3 0 0 3 3 3 0 HP0268 Med26 PF08711.11 CBY14818.1 - 9.1e-10 38.4 0.0 4.8e-09 36.1 0.0 2.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_M PF07500.14 CBY14818.1 - 5.7e-06 26.8 1.2 5.7e-06 26.8 1.2 2.4 1 1 1 2 2 2 1 Transcription factor S-II (TFIIS), central domain Lipase_GDSL_3 PF14606.6 CBY14818.1 - 0.036 14.2 0.3 0.1 12.7 0.0 1.8 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family AAA_assoc_C PF09821.9 CBY14818.1 - 0.062 13.8 0.4 0.062 13.8 0.4 2.8 2 1 0 2 2 2 0 C-terminal AAA-associated domain Latarcin PF10279.9 CBY14818.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.7 2 2 0 2 2 2 0 Latarcin precursor XH PF03469.14 CBY14818.1 - 3.1 7.7 7.9 0.76 9.7 3.4 2.2 2 1 0 2 2 2 0 XH domain zf-DNL PF05180.12 CBY14819.1 - 8.2e-30 102.5 2.4 1.2e-29 102.1 2.4 1.2 1 0 0 1 1 1 1 DNL zinc finger Polo_box_3 PF18544.1 CBY14819.1 - 0.046 14.4 0.0 0.066 13.9 0.0 1.3 1 0 0 1 1 1 0 Polo box domain PADR1 PF08063.12 CBY14819.1 - 0.08 12.7 1.0 0.88 9.4 0.0 2.4 2 1 0 2 2 2 0 PADR1 (NUC008) domain DUF4537 PF15057.6 CBY14819.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Myosin_head PF00063.21 CBY14820.1 - 3.6e-224 745.9 0.3 4.3e-224 745.7 0.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CBY14820.1 - 4.7e-17 62.3 0.3 1.3e-16 60.9 0.3 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding AAA_16 PF13191.6 CBY14820.1 - 0.038 14.4 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CBY14820.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 CBY14820.1 - 0.55 10.2 5.4 0.51 10.3 0.6 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Strabismus PF06638.11 CBY14823.1 - 2.4e-203 676.4 0.7 2.8e-203 676.2 0.7 1.0 1 0 0 1 1 1 1 Strabismus protein BNIP3 PF06553.12 CBY14823.1 - 1.2 8.7 5.9 2.6 7.7 5.9 1.4 1 0 0 1 1 1 0 BNIP3 PAP_central PF04928.17 CBY14824.1 - 5.4e-100 333.5 0.0 8.9e-100 332.8 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CBY14824.1 - 1.4e-19 70.4 0.2 1.3e-15 57.5 0.2 3.6 1 1 2 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CBY14824.1 - 7.4e-10 39.0 0.0 2.2e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 CBY14824.1 - 0.0011 18.8 0.1 0.0038 17.0 0.0 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain zf-C2H2 PF00096.26 CBY14826.1 - 4.4e-09 36.3 12.8 8.5e-05 22.8 1.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY14826.1 - 1.2e-06 28.7 0.4 1.2e-06 28.7 0.4 3.3 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY14826.1 - 1.3e-06 28.7 9.9 0.0061 17.3 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY14826.1 - 6.5e-06 26.0 5.5 0.00073 19.5 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY14826.1 - 0.00045 20.4 9.0 0.15 12.4 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY14826.1 - 0.0013 19.1 6.2 0.03 14.7 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_4 PF07975.12 CBY14826.1 - 0.02 15.1 5.1 0.046 13.9 0.4 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 CBY14826.1 - 0.039 14.1 3.2 0.14 12.3 3.2 2.0 1 1 0 1 1 1 0 Zinc ribbon domain PHD PF00628.29 CBY14826.1 - 0.071 13.0 3.4 0.71 9.8 0.6 2.6 2 1 0 2 2 2 0 PHD-finger zf-Di19 PF05605.12 CBY14826.1 - 0.074 13.4 2.9 0.16 12.3 2.9 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.12 CBY14826.1 - 0.11 12.5 3.9 3.4 7.7 3.1 2.3 1 1 1 2 2 2 0 zinc-ribbons Zf_RING PF16744.5 CBY14826.1 - 0.27 11.4 7.1 14 5.9 0.4 3.5 2 1 1 3 3 3 0 KIAA1045 RING finger Vps39_2 PF10367.9 CBY14826.1 - 0.63 10.5 10.5 7.8 7.0 5.3 3.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DOR PF14839.6 CBY14826.1 - 1.7 8.5 6.4 1.1 9.1 2.3 1.9 2 0 0 2 2 2 0 DOR family zf-MYST PF17772.1 CBY14826.1 - 2 8.1 9.0 1.7 8.3 1.7 2.9 2 1 1 3 3 3 0 MYST family zinc finger domain zf-CCHC_2 PF13696.6 CBY14826.1 - 2.3 8.2 6.9 9.2 6.2 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle ParcG PF10274.9 CBY14827.1 - 1.2e-82 276.5 0.0 1.4e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein Pkinase PF00069.25 CBY14828.1 - 2.4e-18 66.5 0.0 2.6e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14828.1 - 5.9e-09 35.6 0.0 6.3e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY14828.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF2152 PF10222.9 CBY14829.1 - 2.4e-83 280.5 1.8 3.5e-83 280.0 1.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65N PF03636.15 CBY14829.1 - 0.007 16.0 0.1 0.01 15.5 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pro_isomerase PF00160.21 CBY14830.1 - 2.1e-36 125.6 0.0 2.8e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2 PF00096.26 CBY14831.1 - 3.6e-13 49.2 40.4 4.4e-06 26.8 1.7 6.1 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY14831.1 - 2.4e-11 43.5 29.3 6.8e-06 26.3 0.6 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY14831.1 - 9e-08 32.3 35.3 0.0029 18.3 1.1 6.0 6 0 0 6 6 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY14831.1 - 2.3e-05 24.5 17.0 0.032 14.5 0.7 4.9 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CBY14831.1 - 0.00064 20.4 8.5 0.062 14.0 0.3 2.2 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CBY14831.1 - 0.0013 18.7 20.1 0.017 15.1 0.4 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.7 CBY14831.1 - 0.018 15.4 16.5 0.063 13.7 0.5 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type SMN PF06003.12 CBY14831.1 - 0.03 13.6 1.2 0.047 12.9 1.2 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-H2C2_5 PF13909.6 CBY14831.1 - 0.053 13.3 0.4 0.053 13.3 0.4 4.2 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zf_ZIC PF18366.1 CBY14831.1 - 0.064 13.4 8.9 1.1 9.4 0.1 3.8 3 0 0 3 3 3 0 Zic proteins zinc finger domain DUF3268 PF11672.8 CBY14831.1 - 0.11 12.9 2.1 0.15 12.3 0.7 1.8 1 1 1 2 2 2 0 zinc-finger-containing domain FYDLN_acid PF09538.10 CBY14831.1 - 1.6 9.4 7.4 0.4 11.4 1.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2HE PF16278.5 CBY14831.1 - 1.7 9.2 14.4 0.27 11.7 1.9 3.8 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Actin_micro PF17003.5 CBY14831.1 - 2.4 7.3 6.0 4 6.5 0.3 2.2 2 0 0 2 2 2 0 Putative actin-like family ASH PF15780.5 CBY14832.1 - 4.8e-06 26.7 0.3 1.4e-05 25.2 0.3 1.8 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SAM_Exu PF18609.1 CBY14832.1 - 2.9 8.1 5.9 0.63 10.2 2.0 1.9 2 0 0 2 2 2 0 Exuperantia SAM-like domain AAA_6 PF12774.7 CBY14833.1 - 1.1e-115 386.1 0.1 3e-115 384.7 0.1 1.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 CBY14833.1 - 1.1e-61 208.8 0.1 2.4e-61 207.6 0.1 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CBY14833.1 - 4.2e-32 111.2 1.9 5.4e-32 110.9 0.3 2.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain DHC_N2 PF08393.13 CBY14833.1 - 8e-21 74.6 0.1 8e-21 74.6 0.1 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CBY14833.1 - 5.3e-15 55.6 0.0 2.1e-08 34.2 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY14833.1 - 2.2e-11 43.6 0.4 0.0021 17.6 0.0 3.7 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_18 PF13238.6 CBY14833.1 - 1.5e-09 38.4 3.2 0.00027 21.5 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 CBY14833.1 - 5.5e-06 26.8 9.7 0.0013 19.2 0.0 4.0 5 0 0 5 5 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CBY14833.1 - 1.8e-05 24.9 0.1 0.3 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CBY14833.1 - 0.00014 21.7 0.1 0.32 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBY14833.1 - 0.00019 21.9 0.1 0.39 11.1 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 CBY14833.1 - 0.00026 21.3 0.1 1.4 9.3 0.0 3.0 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 CBY14833.1 - 0.00029 21.4 0.1 0.0013 19.2 0.1 2.1 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 CBY14833.1 - 0.0003 20.6 5.9 0.018 14.8 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CBY14833.1 - 0.00043 20.6 4.4 0.04 14.2 0.0 3.9 5 0 0 5 5 3 1 AAA domain AAA_28 PF13521.6 CBY14833.1 - 0.00062 20.0 0.1 1.7 8.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CBY14833.1 - 0.0016 18.4 0.5 0.95 9.5 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CBY14833.1 - 0.0054 16.1 0.2 0.05 13.0 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CBY14833.1 - 0.0067 16.4 0.1 0.29 11.0 0.1 2.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 CBY14833.1 - 0.023 15.0 0.6 2.6 8.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CBY14833.1 - 0.028 13.7 0.6 0.28 10.4 0.3 2.3 2 0 0 2 2 2 0 Septin DUF853 PF05872.12 CBY14833.1 - 0.032 12.8 0.4 1.4 7.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) T2SSE PF00437.20 CBY14833.1 - 0.036 13.1 0.1 3.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 CBY14833.1 - 0.049 12.9 0.1 9.3 5.5 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 CBY14833.1 - 0.054 13.2 0.3 0.16 11.8 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 CBY14833.1 - 0.059 13.3 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase PduV-EutP PF10662.9 CBY14833.1 - 0.071 12.9 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 CBY14833.1 - 0.085 12.6 1.0 0.79 9.4 0.1 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_11 PF13086.6 CBY14833.1 - 0.11 12.3 2.1 11 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 CBY14833.1 - 0.11 12.4 0.6 5.9 6.8 0.2 3.1 3 0 0 3 3 2 0 NACHT domain Cytidylate_kin PF02224.18 CBY14833.1 - 0.12 12.1 1.3 1.4 8.7 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase RsgA_GTPase PF03193.16 CBY14833.1 - 0.15 12.0 2.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase dNK PF01712.19 CBY14833.1 - 0.15 11.9 3.0 1.2 9.0 0.1 3.4 3 0 0 3 3 3 0 Deoxynucleoside kinase CbiA PF01656.23 CBY14833.1 - 1.2 9.2 4.5 17 5.5 0.7 3.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-CCHC PF00098.23 CBY14834.1 - 0.28 11.3 1.9 0.64 10.2 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Dimer_Tnp_hAT PF05699.14 CBY14835.1 - 0.0089 15.8 0.3 0.027 14.2 0.3 1.9 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region wnt PF00110.19 CBY14836.1 - 4.4e-24 85.6 1.6 5.4e-24 85.3 1.6 1.1 1 0 0 1 1 1 1 wnt family adh_short PF00106.25 CBY14839.1 - 1.2e-25 90.1 0.3 9e-21 74.2 0.1 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY14839.1 - 1.8e-16 60.4 0.1 2.3e-13 50.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY14839.1 - 1.5e-07 31.5 0.2 2.8e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 CBY14839.1 - 0.024 14.4 0.2 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 CBY14840.1 - 2.9e-26 92.2 0.0 3.7e-21 75.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY14840.1 - 3.2e-16 59.6 0.0 2.9e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY14840.1 - 2.7e-06 27.4 0.0 6.8e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 CBY14840.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RRM_1 PF00076.22 CBY14841.1 - 6e-18 64.4 0.7 9.3e-18 63.8 0.7 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTF2 PF02136.20 CBY14841.1 - 1.3e-17 64.5 0.1 2.6e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_7 PF16367.5 CBY14841.1 - 1.2e-07 31.7 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 CBY14841.1 - 0.0019 18.2 0.1 0.004 17.2 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif GRP PF07172.11 CBY14841.1 - 0.78 10.5 12.5 1.9 9.2 12.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family TDP43_N PF18694.1 CBY14842.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain Pkinase PF00069.25 CBY14843.1 - 5.1e-62 209.6 0.0 7e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 CBY14843.1 - 3.1e-50 171.3 0.0 4.8e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 CBY14843.1 - 3e-44 151.3 0.0 4.3e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY14843.1 - 4.7e-06 25.6 0.6 9.6e-06 24.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CBY14843.1 - 0.0026 17.2 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY14843.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY14843.1 - 0.045 13.1 0.7 0.085 12.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RT_RNaseH PF17917.1 CBY14844.1 - 1.1e-24 86.7 0.0 2.2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY14844.1 - 2.5e-22 78.8 0.0 5.4e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY14844.1 - 1.8e-20 73.3 0.0 5e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CBY14844.1 - 2.3e-18 66.6 0.0 5.3e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY14844.1 - 0.00024 21.2 0.0 0.00072 19.6 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 CBY14844.1 - 0.0047 17.5 0.0 0.013 16.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY14844.1 - 0.021 15.4 0.0 0.058 14.0 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 CBY14844.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 CBY14844.1 - 0.079 13.3 0.1 0.27 11.6 0.1 2.0 1 0 0 1 1 1 0 Retroviral aspartyl protease ATP13 PF12921.7 CBY14844.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase expression RVT_1 PF00078.27 CBY14845.1 - 5.5e-13 48.9 0.0 1.4e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SPX PF03105.19 CBY14846.1 - 0.013 15.4 20.1 0.12 12.3 7.2 2.2 1 1 1 2 2 2 0 SPX domain Csm1_N PF18504.1 CBY14846.1 - 0.1 12.9 0.6 0.1 12.9 0.6 3.8 3 1 0 3 3 3 0 Csm1 N-terminal domain ERM PF00769.19 CBY14846.1 - 0.49 10.2 28.8 1.2 8.9 28.8 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family bZIP_1 PF00170.21 CBY14846.1 - 0.53 10.4 13.2 2.2 8.4 1.3 3.5 2 1 0 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 CBY14846.1 - 0.64 8.8 20.3 0.41 9.5 17.3 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein Packaging_FI PF14000.6 CBY14846.1 - 0.81 10.2 10.6 0.46 10.9 2.2 2.7 2 1 0 3 3 3 0 DNA packaging protein FI CENP-H PF05837.12 CBY14846.1 - 1.9 8.9 19.5 1.1 9.7 3.5 2.7 1 1 0 2 2 2 0 Centromere protein H (CENP-H) MCPsignal PF00015.21 CBY14846.1 - 2 8.2 6.3 0.56 10.0 2.2 2.2 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Tropomyosin_1 PF12718.7 CBY14846.1 - 4.5 7.4 33.6 0.44 10.7 9.6 3.2 3 1 1 4 4 4 0 Tropomyosin like WD40_alt PF14077.6 CBY14846.1 - 5.3 7.0 7.4 3.5 7.6 1.9 2.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif CLZ PF16526.5 CBY14846.1 - 6.1 7.3 20.5 2.8 8.4 5.2 3.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 CBY14846.1 - 6.4 6.8 14.6 0.59 10.2 7.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 CBY14846.1 - 6.4 6.5 12.7 4.5 7.0 10.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Kelch_2 PF07646.15 CBY14848.1 - 0.00014 21.7 0.4 0.25 11.4 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY14848.1 - 0.0063 16.5 0.7 1.7 8.7 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBY14848.1 - 0.019 15.2 1.5 0.44 10.9 0.1 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY14848.1 - 0.031 14.3 0.1 0.57 10.2 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain HEPN_STY4199 PF18729.1 CBY14848.1 - 0.21 10.7 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 STY4199-like HEPN DAGK_cat PF00781.24 CBY14850.1 - 1.2e-25 89.5 0.1 2.4e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PAS_6 PF08348.11 CBY14850.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 YheO-like PAS domain Laminin_EGF PF00053.24 CBY14851.1 - 1.4e-100 329.3 285.3 1.6e-10 40.9 16.3 14.7 15 0 0 15 15 15 13 Laminin EGF domain Laminin_N PF00055.17 CBY14851.1 - 1.6e-66 224.2 0.0 9.6e-66 221.7 0.0 2.5 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) F5_F8_type_C PF00754.25 CBY14851.1 - 6e-05 23.2 0.3 0.00017 21.7 0.3 1.7 1 0 0 1 1 1 1 F5/8 type C domain Laminin_I PF06008.14 CBY14851.1 - 0.0055 16.4 4.8 0.0055 16.4 4.8 5.1 2 1 0 4 4 4 1 Laminin Domain I LOH1CR12 PF10158.9 CBY14851.1 - 0.14 12.2 3.4 0.74 9.8 0.3 2.9 2 0 0 2 2 2 0 Tumour suppressor protein T7SS_ESX_EspC PF10824.8 CBY14851.1 - 2.9 8.4 4.6 3.3 8.2 0.2 3.2 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DUF4259 PF14078.6 CBY14851.1 - 5.1 7.8 11.1 0.36 11.6 4.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) CUB PF00431.20 CBY14852.1 - 4.2e-17 62.5 0.0 7.3e-08 32.7 0.0 4.3 4 0 0 4 4 4 3 CUB domain Mucin2_WxxW PF13330.6 CBY14852.1 - 1.5e-10 41.7 0.2 1.5e-10 41.7 0.2 4.0 4 0 0 4 4 4 2 Mucin-2 protein WxxW repeating region Ldl_recept_a PF00057.18 CBY14852.1 - 2e-08 34.3 57.6 2e-07 31.1 2.4 7.2 8 0 0 8 8 8 4 Low-density lipoprotein receptor domain class A Fib_alpha PF08702.10 CBY14854.1 - 0.00032 20.9 0.3 0.00041 20.6 0.3 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family EGF_3 PF12947.7 CBY14856.1 - 2.2e-11 43.7 27.8 6.3e-10 39.1 12.1 2.3 2 0 0 2 2 2 2 EGF domain EGF PF00008.27 CBY14856.1 - 0.0002 21.6 20.6 0.046 14.0 4.7 2.7 2 1 0 2 2 2 2 EGF-like domain EGF_CA PF07645.15 CBY14856.1 - 0.0021 18.2 28.7 0.18 12.0 13.7 2.3 1 1 1 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 CBY14856.1 - 0.032 14.2 15.5 0.066 13.2 4.3 3.3 3 0 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.7 CBY14856.1 - 0.33 11.6 0.5 0.33 11.6 0.5 3.4 4 0 0 4 4 4 0 Human growth factor-like EGF Baculo_VP91_N PF08475.10 CBY14856.1 - 1.2 8.8 11.7 0.45 10.2 8.5 1.8 1 1 1 2 2 2 0 Viral capsid protein 91 N-terminal EGF_MSP1_1 PF12946.7 CBY14856.1 - 1.5 9.0 20.9 0.41 10.7 8.1 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY14856.1 - 4.8 7.6 22.3 1.3 9.4 5.4 2.3 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site DUF4834 PF16118.5 CBY14857.1 - 0.074 14.0 0.1 0.096 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) VWA PF00092.28 CBY14858.1 - 5.7e-17 62.5 0.7 1.3e-16 61.4 0.7 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY14858.1 - 1.1e-14 54.7 0.0 2.6e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY14858.1 - 6.9e-13 49.2 0.2 3.3e-12 47.0 0.1 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.10 CBY14858.1 - 1.3e-11 44.7 0.0 5.1e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.9 CBY14858.1 - 1.1e-06 28.9 0.1 3.2e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 CBY14858.1 - 0.0019 17.7 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2972 PF11186.8 CBY14858.1 - 0.0038 17.2 0.2 0.0095 15.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2972) CobT_C PF11775.8 CBY14858.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain RE_AlwI PF09491.10 CBY14859.1 - 0.0038 16.1 3.7 0.0045 15.9 3.7 1.0 1 0 0 1 1 1 1 AlwI restriction endonuclease Uso1_p115_C PF04871.13 CBY14859.1 - 0.12 12.8 10.5 0.16 12.3 10.5 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-C3HC4_3 PF13920.6 CBY14862.1 - 1.5e-10 40.8 12.7 2.3e-10 40.1 12.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY14862.1 - 0.0014 18.4 12.9 0.0026 17.6 12.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY14862.1 - 0.0065 16.8 15.4 0.013 15.8 15.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBY14862.1 - 0.41 10.6 15.6 0.84 9.6 15.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain EXS PF03124.14 CBY14863.1 - 4.7e-81 272.7 26.6 4.7e-81 272.7 26.6 1.8 2 0 0 2 2 2 1 EXS family SPX PF03105.19 CBY14863.1 - 5.4e-15 56.2 5.1 8.6e-15 55.5 5.1 1.3 1 0 0 1 1 1 1 SPX domain SPX PF03105.19 CBY14865.1 - 1.9e-25 90.7 14.3 2.5e-14 54.0 6.8 2.3 1 1 0 2 2 2 2 SPX domain Semialdhyde_dhC PF02774.18 CBY14865.1 - 0.025 14.6 0.2 0.028 14.5 0.2 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Itfg2 PF15907.5 CBY14866.1 - 6e-17 61.7 0.2 3.3e-16 59.2 0.0 2.2 2 1 0 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 TUDOR_5 PF18359.1 CBY14866.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Cofilin_ADF PF00241.20 CBY14867.1 - 9.8e-26 89.9 0.1 1.1e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SHIPPO-rpt PF07004.12 CBY14868.1 - 1.5e-16 60.4 31.8 0.00089 20.1 1.6 6.8 6 2 0 6 6 6 5 Sperm-tail PG-rich repeat Cornifin PF02389.15 CBY14868.1 - 1.1 9.4 5.5 0.22 11.7 1.0 2.1 2 1 0 2 2 2 0 Cornifin (SPRR) family DUF3094 PF11293.8 CBY14870.1 - 0.053 13.2 0.1 0.053 13.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) TFIID-31kDa PF02291.15 CBY14872.1 - 2.6e-41 140.5 0.0 3.2e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 CBY14872.1 - 4.9e-06 26.8 0.1 1.1e-05 25.7 0.0 1.6 2 0 0 2 2 2 1 CENP-S protein Histone PF00125.24 CBY14872.1 - 0.00012 22.4 0.1 0.00019 21.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CBY14872.1 - 0.00065 19.7 0.3 0.0017 18.3 0.0 1.8 3 0 0 3 3 3 1 Bromodomain associated CENP-T_C PF15511.6 CBY14872.1 - 0.0012 18.9 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TIP49_C PF17856.1 CBY14872.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 AAA-lid domain CBFD_NFYB_HMF PF00808.23 CBY14872.1 - 0.034 14.4 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ApbA_C PF08546.11 CBY14872.1 - 0.039 14.2 0.2 8.1 6.7 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal AAA_32 PF13654.6 CBY14872.1 - 0.091 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain DNA_methylase PF00145.17 CBY14873.1 - 5e-34 118.1 0.8 8e-34 117.5 0.8 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase MRPL52 PF18699.1 CBY14873.1 - 0.011 15.9 2.1 0.029 14.6 0.1 2.7 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Melibiase_C PF17801.1 CBY14874.1 - 0.037 14.1 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain adh_short PF00106.25 CBY14875.1 - 3.5e-15 56.0 0.7 4.2e-15 55.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY14875.1 - 2e-09 37.4 0.3 2.5e-09 37.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY14875.1 - 2e-08 34.4 0.2 2.5e-08 34.1 0.2 1.1 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 CBY14875.1 - 0.00079 18.7 0.0 0.00084 18.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBY14875.1 - 0.00081 19.9 0.1 0.0014 19.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBY14875.1 - 0.00092 18.6 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 CBY14875.1 - 0.0067 15.9 0.1 0.0078 15.6 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 CBY14875.1 - 0.038 13.3 0.3 0.045 13.0 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CBY14875.1 - 0.04 13.0 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A YjeF_N PF03853.15 CBY14875.1 - 0.055 13.4 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus mIF3 PF14877.6 CBY14875.1 - 0.1 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor adh_short PF00106.25 CBY14876.1 - 1.5e-16 60.5 0.9 2.7e-16 59.6 0.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY14876.1 - 7.1e-10 38.8 0.2 1.3e-09 37.9 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY14876.1 - 2.3e-05 24.4 0.1 3.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 CBY14876.1 - 0.0034 16.6 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_U57 PF05582.12 CBY14876.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 YabG peptidase U57 Pyr_redox_3 PF13738.6 CBY14876.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 CBY14876.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 CBY14876.1 - 0.074 13.6 0.2 0.14 12.8 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M1 PF01433.20 CBY14877.1 - 6.5e-46 156.6 0.0 1.1e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CBY14877.1 - 8e-36 122.6 0.0 1.5e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CBY14877.1 - 8.1e-23 81.6 0.0 1.4e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 CBY14877.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 Nucleos_tra2_C PF07662.13 CBY14878.1 - 2.9e-26 92.6 0.6 5.2e-26 91.8 0.6 1.4 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Gate PF07670.14 CBY14878.1 - 2.9 8.2 7.7 0.38 11.1 2.2 2.3 2 1 0 2 2 2 0 Nucleoside recognition Glyco_transf_64 PF09258.10 CBY14879.1 - 1.6e-55 188.1 0.3 2.1e-55 187.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Nucleos_tra2_C PF07662.13 CBY14879.1 - 1.4e-20 74.0 0.3 1.9e-20 73.6 0.3 1.2 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus REV PF00424.18 CBY14880.1 - 0.13 12.3 0.3 0.3 11.1 0.3 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) LLC1 PF14945.6 CBY14881.1 - 3.4e-31 108.3 0.6 4.1e-31 108.0 0.6 1.1 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Phage_term_sma PF07141.11 CBY14881.1 - 0.014 15.2 0.1 0.02 14.7 0.1 1.2 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit SAP PF02037.27 CBY14882.1 - 6.9e-15 54.4 0.5 1.5e-14 53.3 0.5 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 CBY14882.1 - 1.1e-07 31.6 21.3 1.1e-06 28.3 2.1 4.5 2 2 2 4 4 4 3 Tho1/MOS11 C-terminal domain Roughex PF06020.11 CBY14882.1 - 0.49 9.4 10.3 0.62 9.1 10.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Pkinase PF00069.25 CBY14883.1 - 6.7e-47 160.1 0.0 9.1e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 CBY14883.1 - 3e-38 130.1 0.1 6e-38 129.1 0.1 1.5 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 CBY14883.1 - 3.4e-23 82.2 0.0 4.9e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY14883.1 - 0.0038 16.1 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBY14883.1 - 0.0099 15.4 0.0 0.04 13.4 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL COX4 PF02936.14 CBY14884.1 - 0.036 14.1 0.1 0.24 11.4 0.0 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV HisKA_7TM PF16927.5 CBY14884.1 - 0.043 13.9 0.1 0.044 13.8 0.1 1.1 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase DUF2207 PF09972.9 CBY14884.1 - 0.069 11.9 0.2 0.11 11.2 0.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3278 PF11683.8 CBY14884.1 - 0.092 12.8 1.1 0.21 11.7 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) Reticulon PF02453.17 CBY14886.1 - 2.7e-05 24.2 5.0 0.00014 21.9 5.0 2.0 1 1 0 1 1 1 1 Reticulon RRM_1 PF00076.22 CBY14887.1 - 8.9e-17 60.7 0.0 2.1e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RUN PF02759.19 CBY14888.1 - 6e-12 45.7 0.0 7.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 RUN domain RabGAP-TBC PF00566.18 CBY14889.1 - 7.8e-38 130.3 0.1 1.2e-37 129.6 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.28 CBY14889.1 - 0.033 13.8 0.4 0.072 12.7 0.1 1.7 2 0 0 2 2 2 0 SH3 domain SH3_9 PF14604.6 CBY14889.1 - 0.16 11.8 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain LRR_6 PF13516.6 CBY14890.1 - 1.1e-09 37.5 11.2 0.0082 16.1 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_8 PF13855.6 CBY14890.1 - 0.0097 15.6 1.5 4.2 7.2 0.0 3.3 3 0 0 3 3 3 2 Leucine rich repeat C12orf66_like PF09404.10 CBY14890.1 - 0.012 14.5 0.4 0.022 13.6 0.4 1.5 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like HIP1_clath_bdg PF16515.5 CBY14890.1 - 0.023 15.3 14.1 0.023 15.3 14.1 5.2 1 1 4 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LRR_1 PF00560.33 CBY14890.1 - 0.036 14.6 3.5 64 4.7 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat TraB PF01963.17 CBY14891.1 - 2.6e-20 73.4 0.1 3.6e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 TraB family DUF2046 PF09755.9 CBY14894.1 - 0.00026 20.3 3.6 0.00032 20.1 3.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) GOLGA2L5 PF15070.6 CBY14894.1 - 0.0026 16.5 1.7 0.0028 16.4 1.7 1.0 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 GAS PF13851.6 CBY14894.1 - 0.012 15.0 1.6 0.013 14.9 1.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlxA PF14282.6 CBY14894.1 - 0.079 13.0 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 FlxA-like protein Snapin_Pallidin PF14712.6 CBY14894.1 - 0.094 13.1 0.7 0.094 13.1 0.7 1.6 2 0 0 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.12 CBY14894.1 - 0.12 12.4 1.7 0.17 11.9 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 CBY14894.1 - 0.16 11.1 3.9 0.2 10.7 3.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3461 PF11944.8 CBY14894.1 - 0.21 11.7 4.7 0.27 11.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) FlaC_arch PF05377.11 CBY14894.1 - 0.37 11.2 2.5 0.59 10.6 0.2 2.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 CBY14894.1 - 0.42 9.5 1.2 0.48 9.3 1.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Kri1 PF05178.12 CBY14894.1 - 0.69 10.5 3.7 1.7 9.3 3.6 1.8 1 1 0 1 1 1 0 KRI1-like family DUF4200 PF13863.6 CBY14894.1 - 1 9.7 8.3 2.5 8.5 8.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) PIH1_CS PF18201.1 CBY14895.1 - 2.9e-06 27.6 0.0 3.3e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 PIH1 CS-like domain RRM_1 PF00076.22 CBY14896.1 - 5.3e-06 26.2 0.0 8.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBY14897.1 - 3.9e-22 77.8 0.0 8.6e-08 31.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DREPP PF05558.12 CBY14897.1 - 0.017 15.0 0.0 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide HSP20 PF00011.21 CBY14898.1 - 1.8e-10 40.9 0.4 2.2e-10 40.6 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family TolA_bind_tri PF16331.5 CBY14901.1 - 0.0037 17.3 2.6 0.009 16.1 2.6 1.7 1 1 0 1 1 1 1 TolA binding protein trimerisation LXG PF04740.12 CBY14901.1 - 0.064 13.0 3.8 0.089 12.5 3.8 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Mt_ATP-synt_B PF05405.14 CBY14901.1 - 0.086 12.5 5.4 0.16 11.6 5.4 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Syntaxin_2 PF14523.6 CBY14901.1 - 0.1 13.0 4.2 0.12 12.7 2.6 1.9 1 1 1 2 2 2 0 Syntaxin-like protein DUF883 PF05957.13 CBY14901.1 - 0.25 12.0 2.7 0.46 11.1 2.7 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DctP PF03480.13 CBY14901.1 - 0.27 10.5 3.8 0.37 10.1 3.8 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 YtxH PF12732.7 CBY14901.1 - 2.8 8.6 8.0 20 5.8 1.2 2.5 1 1 1 2 2 2 0 YtxH-like protein Neur_chan_LBD PF02931.23 CBY14902.1 - 1e-42 146.0 0.9 4.6e-38 130.8 0.2 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY14902.1 - 2.4e-24 86.7 6.6 3.8e-24 86.1 6.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MARVEL PF01284.23 CBY14904.1 - 0.0096 16.0 11.7 0.68 9.9 12.9 2.3 2 1 0 2 2 2 1 Membrane-associating domain DUF3533 PF12051.8 CBY14904.1 - 1.9 7.3 7.6 0.81 8.6 4.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) DUF4131 PF13567.6 CBY14904.1 - 7.8 6.1 9.0 38 3.9 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) HEAT_2 PF13646.6 CBY14905.1 - 8e-07 29.4 1.3 4.6e-06 26.9 0.9 2.4 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 CBY14905.1 - 0.00013 21.9 0.7 1.7 9.1 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 CBY14905.1 - 0.0011 19.4 6.5 0.21 12.1 0.0 3.9 4 0 0 4 4 4 2 HEAT-like repeat Gal-3-0_sulfotr PF06990.11 CBY14907.1 - 7.1e-11 41.6 0.0 1.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY14907.1 - 0.049 13.5 0.2 0.14 12.0 0.2 1.7 1 1 0 1 1 1 0 Sulfotransferase family SNF PF00209.18 CBY14908.1 - 5.7e-193 642.3 29.4 6.7e-193 642.1 29.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Sulfotransfer_1 PF00685.27 CBY14909.1 - 7.4e-09 35.5 0.4 3.4e-08 33.3 0.1 2.2 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY14909.1 - 1.5e-05 25.5 1.1 0.00016 22.2 1.1 2.6 1 1 0 1 1 1 1 Sulfotransferase family Phospholamban PF04272.14 CBY14909.1 - 0.095 12.2 0.2 0.25 10.8 0.2 1.7 1 0 0 1 1 1 0 Phospholamban Ric8 PF10165.9 CBY14912.1 - 1.5e-07 30.9 0.0 1.7e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Fringe PF02434.16 CBY14913.1 - 2.7e-06 27.0 0.4 6.2e-06 25.8 0.4 1.6 1 1 0 1 1 1 1 Fringe-like Collagen PF01391.18 CBY14914.1 - 4.6e-57 189.6 226.8 6.6e-09 35.4 21.2 8.4 1 1 7 8 8 8 8 Collagen triple helix repeat (20 copies) Peptidase_C14 PF00656.22 CBY14915.1 - 5.8e-05 23.2 0.0 7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DDE_Tnp_1_assoc PF13808.6 CBY14916.1 - 0.12 12.5 0.0 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-associated DnaJ PF00226.31 CBY14917.1 - 1.6e-13 50.6 1.5 1.6e-13 50.6 1.5 2.2 2 0 0 2 2 2 1 DnaJ domain DUF4663 PF15668.5 CBY14919.1 - 0.67 9.0 6.7 0.81 8.7 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Serinc PF03348.15 CBY14922.1 - 1.3e-57 195.7 27.4 3e-32 112.1 19.3 2.2 2 0 0 2 2 2 2 Serine incorporator (Serinc) DUF2615 PF11027.8 CBY14922.1 - 6.5 6.9 7.3 2.4 8.4 0.1 3.9 5 1 1 6 6 6 0 Protein of unknown function (DUF2615) EGF_CA PF07645.15 CBY14923.1 - 1.8e-178 578.6 420.6 8.1e-11 41.9 9.0 28.6 27 2 1 28 28 28 25 Calcium-binding EGF domain EGF_3 PF12947.7 CBY14923.1 - 7.9e-124 403.5 439.3 6.7e-10 39.0 10.7 28.2 27 1 1 28 28 28 24 EGF domain cEGF PF12662.7 CBY14923.1 - 2.2e-94 308.8 224.8 1.8e-07 30.9 2.4 26.1 26 0 0 26 26 26 21 Complement Clr-like EGF-like EGF PF00008.27 CBY14923.1 - 1.8e-46 156.0 366.0 5.8e-06 26.5 8.8 28.3 27 1 0 27 27 27 22 EGF-like domain hEGF PF12661.7 CBY14923.1 - 1.1e-29 102.0 288.2 8.8e-05 23.0 1.7 28.9 28 1 0 28 28 28 19 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY14923.1 - 4.3e-23 81.1 329.7 0.00072 19.6 4.9 24.6 25 1 1 26 26 26 17 MSP1 EGF domain 1 VWA PF00092.28 CBY14923.1 - 2.2e-17 63.8 0.0 3.3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 CBY14923.1 - 1.1e-11 44.9 359.6 0.036 14.3 10.0 26.8 18 8 9 27 27 27 18 Coagulation Factor Xa inhibitory site fn3 PF00041.21 CBY14923.1 - 2e-07 31.3 0.0 0.00039 20.7 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Plasmod_Pvs28 PF06247.11 CBY14923.1 - 3.1e-07 30.6 316.2 0.0011 19.2 8.3 25.4 23 2 1 24 24 24 16 Pvs28 EGF domain Glyco_hydro_9 PF00759.19 CBY14924.1 - 9.4e-30 104.4 3.3 1e-29 104.2 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Kelch_6 PF13964.6 CBY14925.1 - 0.5 10.7 5.9 9.9 6.6 0.0 4.0 4 1 1 5 5 5 0 Kelch motif Tubulin PF00091.25 CBY14926.1 - 1.8e-68 230.6 0.0 2.5e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY14926.1 - 2.7e-52 176.2 0.0 4.2e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY14926.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MFS_1 PF07690.16 CBY14929.1 - 7.8e-09 34.9 11.0 1.3e-08 34.2 11.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily EF1G PF00647.19 CBY14929.1 - 0.017 15.1 0.4 0.049 13.7 0.2 1.8 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain B_solenoid_ydck PF18836.1 CBY14929.1 - 0.027 14.3 0.1 7.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Beta solenoid repeat from YDCK Rhomboid PF01694.22 CBY14931.1 - 0.00048 20.2 1.0 0.00048 20.2 1.0 1.9 1 1 1 2 2 2 1 Rhomboid family ECF_trnsprt PF12822.7 CBY14931.1 - 0.024 14.7 0.6 0.027 14.5 0.6 1.0 1 0 0 1 1 1 0 ECF transporter, substrate-specific component DUF3561 PF12084.8 CBY14931.1 - 0.053 13.5 0.2 0.081 12.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) DUF4064 PF13273.6 CBY14931.1 - 1 9.7 6.3 0.23 11.7 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Rhomboid PF01694.22 CBY14932.1 - 1.2e-14 54.6 1.9 2e-14 53.9 1.9 1.3 1 0 0 1 1 1 1 Rhomboid family RT_RNaseH_2 PF17919.1 CBY14935.1 - 6.8e-27 93.4 0.0 3.4e-26 91.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY14935.1 - 5.4e-22 78.1 0.0 1.2e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY14935.1 - 1.2e-18 67.4 0.0 3.4e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Autoind_bind PF03472.15 CBY14935.1 - 0.03 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain Mpv17_PMP22 PF04117.12 CBY14937.1 - 2.5e-21 75.7 2.6 2.5e-21 75.7 2.6 2.8 3 1 0 3 3 3 1 Mpv17 / PMP22 family SHP PF03579.13 CBY14937.1 - 0.061 13.3 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Small hydrophobic protein Linker_histone PF00538.19 CBY14937.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 linker histone H1 and H5 family Mpv17_PMP22 PF04117.12 CBY14938.1 - 1.4e-24 86.1 1.8 1.4e-24 86.1 1.8 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family ABC_tran PF00005.27 CBY14940.1 - 1.9e-49 167.7 0.0 2.8e-28 99.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBY14940.1 - 5.3e-38 131.2 33.9 5.2e-20 72.2 8.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CBY14940.1 - 2.8e-12 46.5 3.0 2.7e-07 30.2 0.5 4.1 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBY14940.1 - 1.8e-07 31.3 1.3 0.027 14.3 0.1 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBY14940.1 - 1.2e-06 29.0 0.2 0.0063 16.9 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CBY14940.1 - 3.9e-06 26.5 0.2 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBY14940.1 - 1e-05 25.5 1.1 0.024 14.7 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY14940.1 - 3.7e-05 23.7 0.3 0.03 14.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 CBY14940.1 - 0.00016 21.5 0.2 0.45 10.2 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_23 PF13476.6 CBY14940.1 - 0.00032 21.3 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CBY14940.1 - 0.00033 20.2 0.1 0.98 8.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DEAD PF00270.29 CBY14940.1 - 0.0024 17.7 0.0 5.4 6.8 0.0 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF815 PF05673.13 CBY14940.1 - 0.0031 16.7 0.3 1.6 7.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 CBY14940.1 - 0.0063 16.2 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 CBY14940.1 - 0.011 15.0 0.1 0.21 10.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 CBY14940.1 - 0.012 15.3 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBY14940.1 - 0.024 14.9 1.6 12 6.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA PF00004.29 CBY14940.1 - 0.026 14.9 2.0 14 6.1 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CBY14940.1 - 0.032 13.2 0.1 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CBY14940.1 - 0.037 14.6 0.1 3.2 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CBY14940.1 - 0.057 13.4 0.2 11 6.0 0.0 3.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CBY14940.1 - 0.07 12.3 1.4 1.2 8.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Sigma54_activat PF00158.26 CBY14940.1 - 0.074 12.7 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 CBY14940.1 - 0.082 12.5 0.1 8.5 5.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 CBY14940.1 - 0.11 12.6 2.5 5.1 7.1 0.2 2.5 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 CBY14940.1 - 0.14 12.5 0.1 10 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 CBY14940.1 - 0.36 10.9 1.6 0.92 9.6 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain RdRP PF05183.12 CBY14941.1 - 9.7e-88 295.3 0.0 1.6e-87 294.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Exo_endo_phos PF03372.23 CBY14943.1 - 5.5e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TF_AP-2 PF03299.14 CBY14943.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Transcription factor AP-2 Serine_protease PF18405.1 CBY14944.1 - 0.057 12.6 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 Gammaproteobacterial serine protease Spc24 PF08286.11 CBY14945.1 - 1.7 8.9 11.0 0.11 12.8 2.6 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 TMEM192 PF14802.6 CBY14945.1 - 3.6 6.6 6.3 0.96 8.5 0.2 2.5 3 0 0 3 3 3 0 TMEM192 family TPR_8 PF13181.6 CBY14946.1 - 1.1e-24 84.5 17.1 0.0028 17.7 0.2 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 CBY14946.1 - 4e-23 79.6 17.7 0.00034 20.5 0.3 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBY14946.1 - 1.5e-21 75.2 19.5 1.6e-06 27.7 0.3 7.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBY14946.1 - 3.6e-14 53.1 1.2 5.1e-07 30.2 0.0 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY14946.1 - 3.7e-14 52.2 7.5 0.091 13.6 0.0 8.6 5 2 4 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBY14946.1 - 1.3e-13 50.4 12.5 0.00013 21.6 1.1 5.5 3 1 2 5 5 5 4 TPR repeat TPR_17 PF13431.6 CBY14946.1 - 6.4e-12 45.0 18.3 6.5e-05 23.0 0.2 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY14946.1 - 8.4e-12 45.4 1.3 0.089 13.3 0.0 6.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY14946.1 - 3.5e-11 43.0 12.9 0.017 15.7 0.1 8.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY14946.1 - 4e-11 43.0 11.8 0.00083 19.6 0.9 6.4 5 1 3 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBY14946.1 - 1.4e-10 40.4 10.8 0.013 15.5 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.10 CBY14946.1 - 1.5e-05 24.2 0.2 0.012 14.6 0.1 2.4 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 CBY14946.1 - 9.4e-05 22.2 3.3 15 5.7 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY14946.1 - 0.0021 18.2 0.0 1.7 8.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBY14946.1 - 0.0043 16.3 2.6 0.0043 16.3 2.6 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CBY14946.1 - 0.0096 16.2 1.5 2.3 8.6 0.0 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat PAP2 PF01569.21 CBY14947.1 - 2.4e-14 53.2 5.4 6.1e-14 52.0 5.4 1.7 1 0 0 1 1 1 1 PAP2 superfamily EamA PF00892.20 CBY14947.1 - 0.009 16.2 3.6 0.009 16.2 3.6 2.8 3 0 0 3 3 3 1 EamA-like transporter family DUF4131 PF13567.6 CBY14947.1 - 0.94 9.1 7.4 7.8 6.1 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Glyco_hydro_1 PF00232.18 CBY14948.1 - 2e-132 441.8 4.1 2.8e-132 441.4 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Secretin_N PF03958.17 CBY14949.1 - 0.22 11.9 0.8 0.38 11.2 0.8 1.6 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain TSP_1 PF00090.19 CBY14949.1 - 2.4 8.5 13.1 0.8 10.0 8.1 2.4 2 0 0 2 2 2 0 Thrombospondin type 1 domain Shisa PF13908.6 CBY14951.1 - 9.1e-06 26.0 0.2 9.1e-06 26.0 0.2 2.6 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.6 CBY14951.1 - 0.0065 14.9 0.1 0.009 14.5 0.1 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Prominin PF05478.11 CBY14951.1 - 0.032 12.2 1.9 0.05 11.6 1.9 1.2 1 0 0 1 1 1 0 Prominin EphA2_TM PF14575.6 CBY14951.1 - 0.16 12.9 0.0 0.16 12.9 0.0 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Corona_S2 PF01601.16 CBY14951.1 - 0.75 8.2 3.7 1 7.7 3.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF4006 PF13179.6 CBY14951.1 - 1.1 9.2 5.6 2.9 7.9 5.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) ECSCR PF15820.5 CBY14951.1 - 1.2 9.0 10.0 0.38 10.6 3.6 2.4 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator RIFIN PF02009.16 CBY14951.1 - 1.6 8.6 8.0 4.1 7.2 2.7 2.2 2 0 0 2 2 2 0 Rifin Tetraspanin PF00335.20 CBY14952.1 - 3.5e-44 151.2 7.4 3.9e-44 151.1 7.4 1.0 1 0 0 1 1 1 1 Tetraspanin family AbrB-like PF14250.6 CBY14952.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AbrB-like transcriptional regulator Scm3 PF10384.9 CBY14952.1 - 0.99 9.2 4.0 0.79 9.5 1.5 2.0 2 0 0 2 2 2 0 Centromere protein Scm3 PRA1 PF03208.19 CBY14952.1 - 6.7 6.3 8.8 4.3 7.0 6.4 1.8 2 0 0 2 2 2 0 PRA1 family protein Sec39 PF08314.11 CBY14954.1 - 0.048 12.1 0.1 0.048 12.1 0.1 1.0 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Methyltransf_22 PF13383.6 CBY14955.1 - 6e-15 55.5 0.1 1.1e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Neur_chan_memb PF02932.16 CBY14956.1 - 8.4e-26 91.5 0.5 8.9e-26 91.4 0.5 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region UIM PF02809.20 CBY14958.1 - 0.0058 16.5 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif Calmodulin_bind PF07887.11 CBY14958.1 - 0.015 14.6 0.8 0.058 12.7 0.1 1.9 2 0 0 2 2 2 0 Calmodulin binding protein-like zf-C3HC4_3 PF13920.6 CBY14959.1 - 6.2e-10 38.8 7.8 9.5e-10 38.2 7.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY14959.1 - 2.1e-08 34.0 9.6 3.4e-08 33.3 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY14959.1 - 1.5e-07 31.6 9.4 2.4e-07 30.9 9.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY14959.1 - 3.7e-07 29.9 5.7 3.3e-06 26.9 6.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY14959.1 - 4.4e-06 26.6 8.6 5.7e-05 23.1 2.7 2.3 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_4 PF14570.6 CBY14959.1 - 1.9e-05 24.3 8.1 3.1e-05 23.7 8.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY14959.1 - 2.2e-05 24.2 6.6 5e-05 23.1 6.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY14959.1 - 4e-05 23.4 8.2 7.8e-05 22.4 8.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 CBY14959.1 - 0.00042 20.4 8.1 0.0042 17.2 8.1 2.2 1 1 0 1 1 1 1 FYVE zinc finger Baculo_IE-1 PF05290.11 CBY14959.1 - 0.0022 18.0 6.0 0.0028 17.6 6.0 1.4 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 CBY14959.1 - 0.0068 15.8 18.0 0.07 12.5 17.8 1.9 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_11 PF17123.5 CBY14959.1 - 0.0091 15.7 9.7 0.023 14.4 4.8 2.5 2 0 0 2 2 2 1 RING-like zinc finger DUF1635 PF07795.11 CBY14959.1 - 0.03 14.2 2.9 0.031 14.1 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF5402 PF17393.2 CBY14959.1 - 0.093 12.7 2.2 3.3 7.7 0.2 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5402) zf-C3HC4_4 PF15227.6 CBY14959.1 - 0.33 11.1 10.7 1.1e+02 3.0 12.1 3.1 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 CBY14959.1 - 2.2 8.3 10.7 9.1 6.3 0.1 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2_4 PF13894.6 CBY14959.1 - 5.3 8.1 8.8 4.7 8.3 0.1 3.0 2 1 1 3 3 3 0 C2H2-type zinc finger DUF2256 PF10013.9 CBY14959.1 - 7.8 6.7 9.9 0.49 10.6 1.4 2.7 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) SRCR PF00530.18 CBY14960.1 - 2.1e-25 89.1 1.0 2e-13 50.7 0.0 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 CBY14960.1 - 2.3e-05 24.9 6.4 0.0037 17.8 0.1 3.2 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 CBY14960.1 - 0.00019 21.9 0.0 0.28 11.7 0.0 2.5 2 0 0 2 2 2 2 Hepsin, SRCR domain Mucin PF01456.17 CBY14960.1 - 0.0056 16.7 48.9 0.01 15.8 48.9 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein MGC-24 PF05283.11 CBY14960.1 - 0.33 11.4 20.4 0.57 10.6 20.4 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Neur_chan_LBD PF02931.23 CBY14961.1 - 1.7e-22 80.0 0.2 2e-22 79.7 0.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY14962.1 - 2e-33 116.5 6.6 6.8e-28 98.3 4.8 2.0 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region ABC2_membrane_5 PF13346.6 CBY14962.1 - 0.13 11.8 6.9 0.21 11.1 6.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Orai-1 PF07856.12 CBY14962.1 - 2.5 7.7 7.1 12 5.5 0.3 2.2 2 0 0 2 2 2 0 Mediator of CRAC channel activity PalH PF08733.10 CBY14962.1 - 4.6 6.2 6.8 0.42 9.6 1.4 1.8 2 0 0 2 2 2 0 PalH/RIM21 Kelch_4 PF13418.6 CBY14963.1 - 2.1e-06 27.7 5.0 0.24 11.5 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY14963.1 - 2.2e-05 24.6 4.4 0.26 11.6 0.0 4.9 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 CBY14963.1 - 0.02 14.8 0.6 2.9 8.0 0.0 4.0 4 1 0 4 4 4 0 Kelch motif PFU PF09070.11 CBY14963.1 - 0.023 15.0 0.5 7.5 6.8 0.1 2.4 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) Kelch_1 PF01344.25 CBY14963.1 - 0.082 12.5 0.7 8.2 6.1 0.0 3.8 4 0 0 4 4 4 0 Kelch motif DivIC PF04977.15 CBY14964.1 - 0.011 15.5 1.7 1.3 8.8 1.0 2.7 2 0 0 2 2 2 0 Septum formation initiator Kelch_6 PF13964.6 CBY14964.1 - 0.012 15.9 1.9 1.1 9.7 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Fungal_TACC PF12709.7 CBY14964.1 - 0.025 15.0 2.1 0.057 13.9 1.2 2.0 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Kelch_2 PF07646.15 CBY14964.1 - 0.028 14.4 3.1 0.91 9.6 0.0 3.6 4 0 0 4 4 4 0 Kelch motif DUF4446 PF14584.6 CBY14964.1 - 0.036 14.0 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Nas2_N PF18265.1 CBY14964.1 - 0.085 12.8 0.6 0.17 11.8 0.6 1.5 1 0 0 1 1 1 0 Nas2 N_terminal domain SHE3 PF17078.5 CBY14964.1 - 0.098 12.4 1.0 0.17 11.6 1.0 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 RPW8 PF05659.11 CBY14964.1 - 0.15 11.7 0.2 0.31 10.7 0.2 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Erf4 PF10256.9 CBY14964.1 - 0.15 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family TMF_TATA_bd PF12325.8 CBY14964.1 - 0.2 11.9 4.0 0.41 10.9 4.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 CBY14964.1 - 0.26 11.4 4.9 0.47 10.5 4.9 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 CBY14964.1 - 0.27 11.5 7.7 5.7 7.3 0.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Kelch_4 PF13418.6 CBY14964.1 - 0.3 11.1 2.3 16 5.6 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain bZIP_1 PF00170.21 CBY14964.1 - 0.47 10.6 5.8 2.5 8.3 0.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor Kelch_5 PF13854.6 CBY14964.1 - 0.9 9.6 0.0 0.9 9.6 0.0 3.4 4 0 0 4 4 4 0 Kelch motif TMF_DNA_bd PF12329.8 CBY14964.1 - 1.1 9.3 8.1 0.35 10.9 2.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 CBY14964.1 - 1.2 9.4 5.4 0.64 10.3 1.4 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 CBY14964.1 - 1.3 9.7 5.1 32 5.2 4.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF4200 PF13863.6 CBY14964.1 - 1.3 9.4 8.1 2.3 8.6 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ZapB PF06005.12 CBY14964.1 - 2.1 8.9 7.3 6.4 7.3 7.3 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Pkinase PF00069.25 CBY14966.1 - 7.1e-22 78.0 0.0 1.6e-21 76.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY14966.1 - 1.2e-15 57.5 0.0 1.2e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY14966.1 - 0.0015 17.9 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY14966.1 - 0.0089 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY14966.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.27 CBY14967.1 - 4.4e-10 39.4 0.0 9.9e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 CBY14967.1 - 0.0049 16.5 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) Peptidase_A17 PF05380.13 CBY14967.1 - 0.055 13.5 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Pao retrotransposon peptidase DUF4364 PF14277.6 CBY14968.1 - 0.45 10.3 6.3 1.6 8.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) GTP_EFTU PF00009.27 CBY14969.1 - 3.6e-46 157.2 0.0 6e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBY14969.1 - 1.9e-15 56.7 0.0 4.8e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 CBY14969.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MOZ_SAS PF01853.18 CBY14970.1 - 1.1e-79 266.3 0.1 2.2e-79 265.3 0.1 1.6 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY14970.1 - 1e-22 79.5 6.1 1.4e-22 79.0 4.0 2.3 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 CBY14970.1 - 6.2e-13 48.4 0.7 1.3e-12 47.3 0.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CBY14970.1 - 0.001 19.4 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY14970.1 - 0.025 14.8 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Chromo PF00385.24 CBY14970.1 - 0.031 14.2 0.6 0.083 12.8 0.6 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Efg1 PF10153.9 CBY14970.1 - 0.45 10.9 5.1 0.79 10.1 0.8 2.2 1 1 1 2 2 2 0 rRNA-processing protein Efg1 BTB_2 PF02214.22 CBY14971.1 - 6.2e-19 68.1 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CBY14971.1 - 0.023 14.9 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain WD40 PF00400.32 CBY14972.1 - 1.2e-05 26.0 3.7 0.36 11.8 0.3 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat RRM_1 PF00076.22 CBY14973.1 - 6.9e-19 67.4 0.6 1.6e-08 34.2 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 CBY14973.1 - 0.00041 19.7 1.1 0.081 12.5 0.0 3.6 3 0 0 3 3 3 1 Lsm interaction motif Nup35_RRM_2 PF14605.6 CBY14973.1 - 0.014 15.4 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EspB PF05802.11 CBY14973.1 - 0.63 10.0 5.3 1.4 8.9 5.3 1.5 1 0 0 1 1 1 0 Enterobacterial EspB protein AP-5_subunit_s1 PF15001.6 CBY14973.1 - 3.7 7.5 8.0 3 7.8 4.2 2.4 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 RRM_1 PF00076.22 CBY14974.1 - 6.8e-15 54.6 0.0 1.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.20 CBY14975.1 - 7.1e-17 61.1 0.4 8.3e-17 60.9 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Sec7_N PF12783.7 CBY14975.1 - 0.0023 17.8 0.6 0.0032 17.4 0.5 1.4 1 1 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Cnd1 PF12717.7 CBY14975.1 - 0.021 14.9 0.1 0.036 14.1 0.0 1.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBY14975.1 - 0.086 13.1 0.2 3.4 8.2 0.0 2.6 3 0 0 3 3 3 0 HEAT repeat Adaptin_N PF01602.20 CBY14976.1 - 8.8e-13 47.6 0.0 1.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region RRM_1 PF00076.22 CBY14976.1 - 1.5e-05 24.8 0.1 9.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med8 PF10232.9 CBY14977.1 - 1.5e-35 122.9 0.0 1.8e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF4410 PF14366.6 CBY14977.1 - 0.18 11.7 0.7 0.67 9.9 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) ThrE PF06738.12 CBY14977.1 - 0.21 10.9 0.1 0.48 9.8 0.1 1.5 2 0 0 2 2 2 0 Putative threonine/serine exporter TSP_1 PF00090.19 CBY14982.1 - 7.4e-107 349.5 242.3 6.3e-10 39.1 9.1 14.5 14 0 0 14 14 14 14 Thrombospondin type 1 domain bZIP_Maf PF03131.17 CBY14982.1 - 0.47 11.0 1.7 1.3 9.6 1.7 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Rhomboid PF01694.22 CBY14983.1 - 5e-31 107.7 13.9 5e-31 107.7 13.9 1.8 2 0 0 2 2 2 1 Rhomboid family Cytochrom_B561 PF03188.16 CBY14983.1 - 9.1 6.4 11.0 1.4 9.1 1.3 2.3 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 UPF0242 PF06785.11 CBY14985.1 - 5.1e-06 26.7 2.9 9.2e-06 25.9 2.9 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Kelch_5 PF13854.6 CBY14985.1 - 3e-05 23.9 1.1 0.0031 17.5 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY14985.1 - 0.017 15.4 3.9 5.4 7.4 0.0 4.5 4 2 1 5 5 5 0 Kelch motif Leu_zip PF15294.6 CBY14985.1 - 0.033 13.7 4.1 0.053 13.0 4.1 1.3 1 0 0 1 1 1 0 Leucine zipper Kelch_4 PF13418.6 CBY14985.1 - 0.044 13.8 0.6 7.4 6.7 0.2 2.9 2 1 0 2 2 2 0 Galactose oxidase, central domain YabA PF06156.13 CBY14985.1 - 0.05 14.2 8.5 0.83 10.3 2.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF2681 PF10883.8 CBY14985.1 - 0.083 13.3 1.9 0.44 11.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) APC_N_CC PF16689.5 CBY14985.1 - 0.1 12.7 0.7 0.29 11.2 0.3 2.0 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Kelch_2 PF07646.15 CBY14985.1 - 0.14 12.2 0.3 9.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Cep57_CLD_2 PF14197.6 CBY14985.1 - 0.16 12.1 12.0 1.4 9.1 11.0 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 SHE3 PF17078.5 CBY14985.1 - 0.36 10.5 7.8 0.7 9.6 7.8 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Csm1_N PF18504.1 CBY14985.1 - 4.4 7.7 6.9 0.28 11.6 1.6 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain Jagunal PF07086.12 CBY14986.1 - 2.4e-32 112.5 3.5 3e-32 112.2 3.5 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis SAM_2 PF07647.17 CBY14987.1 - 1.2e-28 99.0 0.6 5.6e-14 52.0 0.1 2.2 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY14987.1 - 1.9e-21 76.3 0.1 3.7e-16 59.3 0.1 2.2 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Kelch_2 PF07646.15 CBY14988.1 - 0.003 17.5 0.5 1.4 9.0 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY14988.1 - 0.046 14.0 2.6 1.5 9.2 0.1 3.8 4 0 0 4 4 4 0 Kelch motif CCDC85 PF10226.9 CBY14988.1 - 0.14 11.8 0.6 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 CCDC85 family Kelch_5 PF13854.6 CBY14988.1 - 0.34 11.0 0.0 0.34 11.0 0.0 3.7 4 0 0 4 4 4 0 Kelch motif DUF5314 PF17241.2 CBY14991.1 - 0.0015 18.2 0.2 0.0018 18.0 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5314) HMMR_C PF15908.5 CBY14991.1 - 0.032 14.5 0.9 0.043 14.1 0.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal OPA3 PF07047.12 CBY14991.1 - 0.034 13.9 0.1 0.061 13.1 0.0 1.7 1 1 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Phyto_Pns9_10 PF05878.11 CBY14991.1 - 0.062 12.4 0.1 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Trypsin PF00089.26 CBY14992.1 - 9.1e-27 94.3 0.2 9.1e-27 94.3 0.2 2.0 2 1 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY14992.1 - 2.8e-05 25.1 1.1 0.00064 20.6 0.0 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain Tmemb_cc2 PF10267.9 CBY14992.1 - 6 5.9 12.4 11 5.1 12.4 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FPN1 PF06963.12 CBY14993.1 - 7.5e-79 265.3 18.4 8.9e-79 265.1 18.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MscL PF01741.18 CBY14993.1 - 0.21 11.9 6.7 37 4.6 6.7 2.6 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL AP3D1 PF06375.11 CBY14994.1 - 0.082 13.1 0.0 0.088 13.0 0.0 1.0 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Lectin_C PF00059.21 CBY14996.1 - 3.7e-21 75.9 14.5 6.5e-10 39.7 4.5 3.9 4 1 0 4 4 4 3 Lectin C-type domain Seryl_tRNA_N PF02403.22 CBY14996.1 - 0.078 13.2 5.9 0.14 12.4 5.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ExsD PF16806.5 CBY14996.1 - 0.088 12.7 1.5 0.17 11.7 1.5 1.4 1 0 0 1 1 1 0 Antiactivator protein ExsD DUF4446 PF14584.6 CBY14996.1 - 0.1 12.6 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF1664 PF07889.12 CBY14996.1 - 0.23 11.5 0.3 0.44 10.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 CBY14996.1 - 0.44 11.0 7.8 0.79 10.1 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) HIP1_clath_bdg PF16515.5 CBY14996.1 - 0.49 11.0 3.6 0.81 10.3 3.6 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fungal_TACC PF12709.7 CBY14996.1 - 0.66 10.5 4.8 1.4 9.4 4.3 1.8 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPR_MLP1_2 PF07926.12 CBY14996.1 - 1.9 8.5 8.1 3.3 7.8 8.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 CBY14996.1 - 5 7.4 11.1 1.6 9.0 3.5 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper ExsD PF16806.5 CBY14997.1 - 0.012 15.5 0.7 0.02 14.8 0.7 1.3 1 0 0 1 1 1 0 Antiactivator protein ExsD Seryl_tRNA_N PF02403.22 CBY14997.1 - 0.017 15.4 5.9 0.034 14.4 5.9 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4446 PF14584.6 CBY14997.1 - 0.028 14.4 0.3 0.044 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4407 PF14362.6 CBY14997.1 - 0.067 12.5 0.5 0.12 11.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CBY14997.1 - 0.073 13.1 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Kelch_2 PF07646.15 CBY14997.1 - 0.11 12.5 0.0 0.62 10.1 0.0 2.3 3 0 0 3 3 3 0 Kelch motif HIP1_clath_bdg PF16515.5 CBY14997.1 - 0.11 13.1 3.6 0.19 12.4 3.6 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4200 PF13863.6 CBY14997.1 - 0.12 12.8 8.0 0.19 12.1 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Lectin_N PF03954.14 CBY14997.1 - 0.22 11.3 1.3 0.34 10.6 1.3 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Fungal_TACC PF12709.7 CBY14997.1 - 0.24 11.8 6.0 0.5 10.8 4.4 2.1 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins RPW8 PF05659.11 CBY14997.1 - 0.27 10.9 2.0 0.41 10.3 1.2 1.6 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 HALZ PF02183.18 CBY14997.1 - 0.51 10.6 11.1 0.5 10.6 3.5 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 CBY14997.1 - 0.52 10.4 8.3 0.9 9.6 8.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 CBY14997.1 - 1.9 8.6 8.6 6 7.0 0.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 CBY14997.1 - 2 9.1 5.9 40 4.9 5.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Swi5 PF07061.11 CBY14997.1 - 2 8.5 6.3 0.38 10.9 2.0 2.0 2 0 0 2 2 2 0 Swi5 ZapB PF06005.12 CBY14997.1 - 2.9 8.4 12.1 12 6.4 12.1 2.0 1 1 0 1 1 1 0 Cell division protein ZapB IFP_35_N PF07334.13 CBY14997.1 - 6 7.0 7.8 1.2 9.3 2.2 2.5 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Kelch_2 PF07646.15 CBY14998.1 - 1.1e-08 34.7 3.6 0.87 9.7 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 CBY14998.1 - 0.0039 17.2 0.1 0.065 13.3 0.0 4.5 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 CBY14998.1 - 0.0044 17.3 8.3 4.8 7.6 0.0 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBY14999.1 - 0.00094 19.1 0.4 0.67 10.0 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY14999.1 - 0.011 16.0 0.7 1.3 9.4 0.1 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY14999.1 - 0.15 12.1 5.3 1.9 8.6 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY14999.1 - 0.16 12.0 0.7 1.2 9.1 0.0 2.9 4 0 0 4 4 4 0 Galactose oxidase, central domain Pkinase PF00069.25 CBY15000.1 - 5.8e-10 39.0 0.0 5.8e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15000.1 - 5e-06 26.0 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase rve PF00665.26 CBY15004.1 - 0.013 15.6 0.0 0.03 14.5 0.0 1.6 2 0 0 2 2 2 0 Integrase core domain UPF0242 PF06785.11 CBY15005.1 - 1.1e-05 25.6 0.8 1.9e-05 24.8 0.8 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 CBY15005.1 - 0.0054 16.3 1.3 0.008 15.7 1.3 1.2 1 0 0 1 1 1 1 Leucine zipper Kelch_5 PF13854.6 CBY15005.1 - 0.0092 15.9 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Csm1_N PF18504.1 CBY15005.1 - 0.041 14.2 1.1 0.1 12.9 1.1 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain YabA PF06156.13 CBY15005.1 - 0.047 14.3 6.9 0.94 10.2 1.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Thg1 PF04446.12 CBY15005.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 tRNAHis guanylyltransferase DUF2681 PF10883.8 CBY15005.1 - 0.067 13.6 0.7 0.29 11.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) PFU PF09070.11 CBY15005.1 - 0.23 11.7 0.6 0.69 10.2 0.1 1.9 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) SHE3 PF17078.5 CBY15005.1 - 0.39 10.4 7.4 0.78 9.4 7.4 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Cep57_CLD_2 PF14197.6 CBY15005.1 - 1.5 9.0 12.9 0.49 10.5 6.5 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 LapA_dom PF06305.11 CBY15005.1 - 1.5 8.7 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ATG16 PF08614.11 CBY15005.1 - 3 8.0 7.8 5.4 7.2 7.8 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 CBY15006.1 - 5.5e-07 29.9 2.1 9.2e-07 29.2 2.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Kelch_5 PF13854.6 CBY15006.1 - 0.00043 20.2 0.0 0.031 14.3 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Leu_zip PF15294.6 CBY15006.1 - 0.0047 16.5 2.5 0.0074 15.8 2.5 1.3 1 0 0 1 1 1 1 Leucine zipper Kelch_6 PF13964.6 CBY15006.1 - 0.018 15.3 0.2 1.8 9.0 0.0 3.4 3 1 1 4 4 4 0 Kelch motif PFU PF09070.11 CBY15006.1 - 0.046 14.0 0.3 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) YabA PF06156.13 CBY15006.1 - 0.11 13.1 8.9 1.1 10.0 2.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF2681 PF10883.8 CBY15006.1 - 0.14 12.6 2.7 0.4 11.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Kelch_4 PF13418.6 CBY15006.1 - 0.16 12.0 0.3 20 5.3 0.2 2.8 2 1 0 2 2 2 0 Galactose oxidase, central domain Ntox1 PF15500.6 CBY15006.1 - 0.23 11.8 0.5 0.48 10.8 0.5 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 SHE3 PF17078.5 CBY15006.1 - 0.23 11.2 9.8 0.46 10.2 9.5 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 ZapB PF06005.12 CBY15006.1 - 0.38 11.2 11.5 1.1 9.8 3.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB APC_N_CC PF16689.5 CBY15006.1 - 1.3 9.1 4.9 0.28 11.3 0.7 2.1 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Cep57_CLD_2 PF14197.6 CBY15006.1 - 1.5 8.9 16.3 1 9.5 8.3 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 SIKE PF05769.11 CBY15006.1 - 5.8 6.8 11.0 12 5.8 5.7 2.3 1 1 1 2 2 2 0 SIKE family Csm1_N PF18504.1 CBY15006.1 - 5.9 7.3 8.9 0.34 11.3 3.4 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain Cadherin PF00028.17 CBY15007.1 - 4.2e-34 116.8 0.2 1.2e-13 51.2 0.1 3.2 3 0 0 3 3 3 3 Cadherin domain Cadherin_2 PF08266.12 CBY15007.1 - 0.0044 16.8 2.0 2.3 8.1 0.6 3.8 3 1 0 3 3 3 1 Cadherin-like RET_CLD1 PF17756.1 CBY15007.1 - 0.013 15.7 0.0 4.5 7.6 0.0 2.6 2 0 0 2 2 2 0 RET Cadherin like domain 1 AAA_14 PF13173.6 CBY15007.1 - 0.099 12.7 2.1 0.19 11.8 0.9 2.1 3 0 0 3 3 3 0 AAA domain PknG_rubred PF16919.5 CBY15008.1 - 0.023 14.8 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain DUF1911 PF08929.10 CBY15011.1 - 0.17 12.7 0.7 0.55 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) Lys PF00062.20 CBY15013.1 - 0.071 13.4 0.3 2.2 8.6 0.1 2.4 2 0 0 2 2 2 0 C-type lysozyme/alpha-lactalbumin family RRP7 PF12923.7 CBY15014.1 - 1e-23 83.7 21.8 1e-23 83.7 21.8 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_7 PF16367.5 CBY15014.1 - 7.3e-05 22.8 0.2 0.00036 20.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif RRM_1 PF00076.22 CBY15014.1 - 0.00081 19.2 0.0 0.0037 17.0 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.6 CBY15014.1 - 0.014 15.8 2.6 0.81 10.2 2.6 2.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.14 CBY15014.1 - 0.056 13.3 12.6 0.098 12.5 12.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MMtag PF10159.9 CBY15014.1 - 0.78 10.1 0.0 0.78 10.1 0.0 3.0 2 1 0 2 2 2 0 Multiple myeloma tumor-associated FUN14 PF04930.15 CBY15015.1 - 2e-08 34.5 0.0 3.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 FUN14 family TMEM189_B_dmain PF10520.9 CBY15017.1 - 5.4e-65 218.7 3.8 6.9e-65 218.4 3.8 1.1 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain DUF3007 PF11460.8 CBY15017.1 - 0.021 15.1 0.2 0.038 14.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) FA_hydroxylase PF04116.13 CBY15017.1 - 0.027 14.8 9.5 0.082 13.3 7.8 2.1 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily SH3_9 PF14604.6 CBY15018.1 - 4.1e-11 42.6 0.1 2.2e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY15018.1 - 4.4e-10 39.0 0.0 1.1e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY15018.1 - 6.9e-05 22.5 0.3 0.00023 20.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain DNA_RNApol_7kD PF03604.13 CBY15019.1 - 7.5e-16 57.5 7.0 9.5e-16 57.2 7.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_13 PF09855.9 CBY15019.1 - 0.03 14.5 0.1 0.03 14.5 0.1 1.8 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) GFA PF04828.14 CBY15019.1 - 0.068 13.5 0.4 4.2 7.8 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme EABR PF12180.8 CBY15020.1 - 1e-05 25.0 1.3 2e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 FUSC PF04632.12 CBY15020.1 - 2.7 6.4 4.4 3.6 6.0 4.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SPT16 PF08644.11 CBY15020.1 - 2.9 8.1 12.3 25 5.0 12.3 2.4 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) FliD_N PF02465.18 CBY15020.1 - 5.1 7.8 12.1 0.82 10.4 5.9 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF148 PF02520.17 CBY15020.1 - 8.1 6.6 18.0 0.49 10.5 7.0 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 CPSF73-100_C PF11718.8 CBY15021.1 - 4.5e-44 150.6 1.5 7.4e-44 149.9 1.5 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CBY15021.1 - 1e-32 112.7 0.0 2.9e-32 111.2 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CBY15021.1 - 2.8e-21 75.2 0.2 5.9e-21 74.2 0.2 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CBY15021.1 - 5.3e-16 59.2 1.2 9.6e-16 58.4 1.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CBY15021.1 - 1.8e-15 56.9 0.0 7.5e-15 54.9 0.0 2.0 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CBY15021.1 - 2.3e-07 30.5 1.3 4.6e-07 29.6 0.2 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBY15021.1 - 0.0054 16.6 0.3 0.6 10.0 0.1 3.0 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Glyco_transf_28 PF03033.20 CBY15021.1 - 0.092 12.8 0.1 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 Glycosyltransferase family 28 N-terminal domain HSP70 PF00012.20 CBY15022.1 - 8.2e-124 414.0 9.1 6e-102 341.8 6.6 3.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CBY15022.1 - 8e-09 34.7 0.1 1.5e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Rhomboid PF01694.22 CBY15023.1 - 1.9e-10 40.9 19.2 6.3e-10 39.2 15.3 2.7 2 1 0 2 2 2 2 Rhomboid family TM231 PF10149.9 CBY15024.1 - 0.00012 21.5 2.0 0.0098 15.3 2.0 2.2 1 1 0 1 1 1 1 Transmembrane protein 231 NAD_binding_1 PF00175.21 CBY15025.1 - 1.1e-13 51.7 0.0 1.7e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CBY15025.1 - 1.7e-10 41.2 0.0 1.1e-07 32.1 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ribosomal_S21e PF01249.18 CBY15026.1 - 7.5e-38 128.5 0.0 8.2e-38 128.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SARAF PF06682.12 CBY15030.1 - 6.3e-58 197.0 0.0 1.5e-57 195.8 0.0 1.5 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis Sortilin-Vps10 PF15902.5 CBY15031.1 - 1.7e-107 360.0 5.3 3e-107 359.2 5.3 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CBY15031.1 - 9.5e-36 123.7 10.2 2e-35 122.6 10.2 1.6 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CBY15031.1 - 1.9e-05 24.0 24.3 9.7 6.7 0.1 9.5 9 0 0 9 9 9 2 BNR/Asp-box repeat BNR_2 PF13088.6 CBY15031.1 - 0.0015 17.9 4.3 0.061 12.6 0.1 4.3 2 1 4 6 6 6 3 BNR repeat-like domain BNR_6 PF15899.5 CBY15031.1 - 2.2 8.6 13.0 50 4.4 0.0 6.1 6 0 0 6 6 6 0 BNR-Asp box repeat HA2 PF04408.23 CBY15032.1 - 1.3e-14 54.4 0.0 1.3e-14 54.4 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY15032.1 - 2.5e-14 53.6 0.0 9.4e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBY15032.1 - 7e-11 42.3 0.0 2e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBY15032.1 - 5e-09 36.2 0.1 1.9e-08 34.2 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY15032.1 - 6e-05 23.3 1.0 0.00063 20.0 1.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY15032.1 - 0.015 15.6 0.2 0.047 14.0 0.2 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CBY15032.1 - 0.057 12.5 0.0 0.42 9.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 CBY15032.1 - 0.076 13.0 5.2 0.056 13.5 0.5 2.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Shisa PF13908.6 CBY15033.1 - 0.0069 16.7 4.4 0.011 16.0 4.4 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator WD40_3 PF15911.5 CBY15033.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 WD domain, G-beta repeat ATP-synt_8 PF00895.20 CBY15033.1 - 0.18 12.3 1.4 0.26 11.8 0.2 1.8 2 0 0 2 2 2 0 ATP synthase protein 8 Lig_chan PF00060.26 CBY15035.1 - 0.042 13.7 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel MRAP PF15183.6 CBY15035.1 - 0.064 13.2 0.2 0.077 13.0 0.2 1.2 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family ATP-synt_8 PF00895.20 CBY15035.1 - 0.073 13.5 0.9 0.11 13.0 0.6 1.4 1 1 0 1 1 1 0 ATP synthase protein 8 PDR_CDR PF06422.12 CBY15035.1 - 0.32 10.9 1.7 0.31 11.0 1.0 1.4 1 1 0 1 1 1 0 CDR ABC transporter RE_SinI PF09570.10 CBY15036.1 - 0.027 13.7 2.3 0.059 12.6 0.4 2.3 1 1 1 2 2 2 0 SinI restriction endonuclease Baculo_PEP_C PF04513.12 CBY15036.1 - 0.3 11.1 5.5 0.5 10.4 4.5 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 CBY15036.1 - 4.2 7.5 19.3 1.1 9.4 6.5 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Patatin PF01734.22 CBY15038.1 - 1e-15 58.5 4.8 1.8e-14 54.4 4.8 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase KH_1 PF00013.29 CBY15039.1 - 8.9e-22 76.7 6.7 1e-16 60.5 0.2 4.3 4 0 0 4 4 4 3 KH domain SAM_1 PF00536.30 CBY15039.1 - 1.1e-12 48.2 0.1 2.4e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY15039.1 - 3.8e-10 39.7 0.0 8.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KH_10 PF17905.1 CBY15039.1 - 4.6e-06 27.0 0.1 0.22 12.0 0.0 3.1 3 1 0 3 3 3 2 GLD-3 KH domain 5 2H-phosphodiest PF08975.10 CBY15039.1 - 0.31 11.0 1.6 3.4 7.7 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1868) betaPIX_CC PF16523.5 CBY15040.1 - 0.0003 20.6 1.5 0.38 10.6 0.6 2.3 2 0 0 2 2 2 2 betaPIX coiled coil SYCE1 PF15233.6 CBY15040.1 - 0.00073 19.6 3.1 0.0013 18.8 3.1 1.3 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 Macoilin PF09726.9 CBY15040.1 - 0.0018 16.9 13.1 0.0022 16.6 13.1 1.0 1 0 0 1 1 1 1 Macoilin family TSC22 PF01166.18 CBY15040.1 - 0.17 12.2 0.4 0.17 12.2 0.4 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 CBY15040.1 - 2 8.2 7.4 0.37 10.6 2.3 2.0 2 0 0 2 2 2 0 Septum formation initiator Kelch_2 PF07646.15 CBY15041.1 - 0.00028 20.7 2.0 2.6 8.1 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CBY15041.1 - 0.014 15.6 0.0 0.061 13.6 0.0 2.2 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY15041.1 - 0.018 15.0 4.7 0.07 13.1 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY15041.1 - 0.41 11.0 6.1 13 6.2 0.1 3.7 2 1 1 3 3 3 0 Kelch motif Connexin PF00029.19 CBY15042.1 - 1.8e-59 201.3 0.6 2.1e-59 201.1 0.6 1.0 1 0 0 1 1 1 1 Connexin ssDNA_DBD PF18333.1 CBY15043.1 - 0.036 14.2 0.3 0.081 13.0 0.3 1.6 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain zf-C2H2 PF00096.26 CBY15046.1 - 3e-13 49.4 21.8 1.2e-05 25.4 1.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY15046.1 - 3.4e-10 39.9 22.1 6.2e-07 29.6 1.7 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY15046.1 - 7.5e-09 35.7 17.9 0.0034 18.1 1.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY15046.1 - 0.0008 19.1 13.7 0.001 18.8 1.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CBY15046.1 - 0.00091 19.2 13.2 0.066 13.2 1.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY15046.1 - 0.017 15.4 0.8 0.017 15.4 0.8 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY15046.1 - 0.028 14.8 0.4 0.028 14.8 0.4 3.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CBY15046.1 - 0.45 10.7 3.9 0.59 10.3 0.9 2.5 2 0 0 2 2 2 0 Zinc ribbon domain RHINO PF15319.6 CBY15046.1 - 1.4 8.9 8.6 0.079 13.0 1.9 2.1 2 0 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein zf-C2HC_2 PF13913.6 CBY15046.1 - 1.9 8.4 7.2 0.27 11.2 2.2 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 CBY15046.1 - 3.2 8.2 12.1 30 5.0 2.1 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ammonium_transp PF00909.21 CBY15047.1 - 2.3e-92 309.8 26.4 2.6e-92 309.6 26.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MASE2 PF05230.11 CBY15047.1 - 0.16 12.1 3.0 1.8 8.7 0.5 3.0 2 0 0 2 2 2 0 MASE2 domain IGFBP PF00219.18 CBY15048.1 - 0.0042 17.7 1.9 0.0042 17.7 1.9 1.8 2 0 0 2 2 2 1 Insulin-like growth factor binding protein hEGF PF12661.7 CBY15049.1 - 1.3 9.8 12.6 5.9 7.7 0.6 4.6 4 0 0 4 4 4 0 Human growth factor-like EGF Pkinase PF00069.25 CBY15050.1 - 5.1e-56 190.0 0.0 6.9e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15050.1 - 1.1e-44 152.7 0.0 1.5e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CBY15050.1 - 6.7e-11 42.3 0.1 1.7e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 CBY15050.1 - 0.00026 19.9 0.0 0.00053 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY15050.1 - 0.029 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4447 PF14590.6 CBY15050.1 - 0.16 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) Trypsin PF00089.26 CBY15051.1 - 1.6e-166 551.3 8.8 5.4e-55 186.6 0.3 3.2 3 0 0 3 3 3 3 Trypsin Trypsin_2 PF13365.6 CBY15051.1 - 2.7e-12 47.8 6.1 0.021 15.8 0.1 5.3 3 3 0 3 3 3 3 Trypsin-like peptidase domain Acyl_transf_2 PF02273.15 CBY15051.1 - 5.1e-06 25.9 0.0 0.42 9.8 0.0 3.6 4 0 0 4 4 4 2 Acyl transferase DUF1986 PF09342.11 CBY15051.1 - 0.0035 17.7 4.8 7.8 6.9 0.1 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF1986) MAR_sialic_bdg PF10564.9 CBY15051.1 - 0.0086 16.1 2.4 0.013 15.5 0.4 2.3 2 0 0 2 2 2 1 Sialic-acid binding micronemal adhesive repeat MetallophosN PF16371.5 CBY15051.1 - 0.026 14.8 0.2 68 3.8 0.0 3.4 3 0 0 3 3 3 0 N terminal of Calcineurin-like phosphoesterase SPARC_Ca_bdg PF10591.9 CBY15051.1 - 0.095 13.0 0.0 1.7e+02 2.6 0.0 3.8 4 0 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region LRR_8 PF13855.6 CBY15052.1 - 3.7e-45 151.5 44.9 1.8e-12 46.8 3.8 7.7 4 2 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 CBY15052.1 - 2.7e-17 62.6 47.3 7.6e-06 26.2 0.2 9.3 7 3 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY15052.1 - 4.5e-11 42.5 27.2 0.0078 15.7 0.6 5.3 2 2 3 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 CBY15052.1 - 3.2e-06 26.9 29.8 2.3 9.1 0.3 11.2 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY15052.1 - 0.00045 20.0 27.4 11 6.3 0.1 9.0 9 0 0 9 9 9 3 Leucine Rich repeat AJAP1_PANP_C PF15298.6 CBY15052.1 - 0.3 11.3 15.0 0.55 10.4 15.0 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mucin PF01456.17 CBY15052.1 - 0.83 9.6 30.8 1.3 9.0 30.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.6 CBY15052.1 - 2.8 7.9 7.2 5 7.0 7.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family FSA_C PF10479.9 CBY15052.1 - 8.6 4.4 12.7 13 3.8 12.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Profilin PF00235.19 CBY15054.1 - 2.1e-24 86.2 0.2 2.3e-24 86.1 0.2 1.0 1 0 0 1 1 1 1 Profilin DUF2079 PF09852.9 CBY15055.1 - 9.4e-05 21.4 1.0 0.00011 21.2 1.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) DUF3144 PF11342.8 CBY15055.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) CBM_14 PF01607.24 CBY15056.1 - 3.3e-05 23.9 7.9 0.00015 21.9 7.9 2.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Sulfotransfer_1 PF00685.27 CBY15057.1 - 2.8e-12 46.7 0.1 4.5e-12 46.0 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY15057.1 - 8.2e-10 39.4 0.0 7.7e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase family CLIP_SPH_mas PF18398.1 CBY15057.1 - 0.31 11.5 1.9 2 8.9 1.9 2.1 1 1 0 1 1 1 0 Clip-domain serine protease homolog masquerade Fibrinogen_C PF00147.18 CBY15058.1 - 5.3e-56 189.9 3.0 8.4e-56 189.2 3.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain RRN3 PF05327.11 CBY15058.1 - 0.1 11.1 15.2 0.18 10.3 15.2 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nif11 PF07862.11 CBY15058.1 - 3.9 7.9 6.6 13 6.2 0.6 2.9 2 0 0 2 2 2 0 Nif11 domain DUF1090 PF06476.12 CBY15058.1 - 8.8 6.5 11.5 1.1 9.4 6.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) IreB PF06135.12 CBY15059.1 - 0.17 12.1 1.5 1.1 9.5 0.2 2.5 2 1 1 3 3 3 0 IreB regulatory phosphoprotein Pkinase PF00069.25 CBY15060.1 - 8.3e-11 41.7 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15060.1 - 4e-07 29.6 0.0 8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SAA PF00277.18 CBY15061.1 - 0.02 15.4 0.1 0.48 10.9 0.0 2.0 1 1 1 2 2 2 0 Serum amyloid A protein PI3K_P85_iSH2 PF16454.5 CBY15061.1 - 0.099 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PolyA_pol PF01743.20 CBY15063.1 - 1.1e-31 109.9 0.9 1.5e-31 109.5 0.9 1.2 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CBY15063.1 - 2.9e-08 33.3 0.5 1.4e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 Probable RNA and SrmB- binding site of polymerase A HCO3_cotransp PF00955.21 CBY15064.1 - 2.1e-160 534.9 5.6 1e-88 298.4 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.13 CBY15064.1 - 3.8e-72 243.3 0.1 1.1e-71 241.8 0.1 1.7 1 1 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 CBY15064.1 - 4.3e-05 23.5 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 UQ_con PF00179.26 CBY15065.1 - 2.3e-41 140.7 0.1 3.7e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY15065.1 - 0.0026 17.5 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBY15065.1 - 0.037 14.3 1.5 0.073 13.4 0.1 2.1 1 1 0 2 2 2 0 RWD domain PHTB1_N PF14727.6 CBY15066.1 - 1.8e-17 63.9 0.3 2.5e-17 63.3 0.3 1.3 1 0 0 1 1 1 1 PTHB1 N-terminus CLTH PF10607.9 CBY15066.1 - 0.072 13.0 2.0 0.14 12.0 2.0 1.5 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain F-actin_cap_A PF01267.17 CBY15067.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 F-actin capping protein alpha subunit G-alpha PF00503.20 CBY15068.1 - 6.5e-102 341.3 6.5 8.3e-102 341.0 6.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY15068.1 - 4.6e-14 52.3 1.2 5e-10 39.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY15068.1 - 9.5e-05 21.9 3.6 0.0023 17.3 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region ATP-synt PF00231.19 CBY15068.1 - 0.0015 18.3 0.3 0.0077 16.0 0.1 2.0 2 0 0 2 2 2 1 ATP synthase Roc PF08477.13 CBY15068.1 - 0.0023 18.1 0.4 0.66 10.2 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CBY15068.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CBY15068.1 - 0.06 12.7 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CBY15068.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nop14 PF04147.12 CBY15069.1 - 2.4 6.3 23.2 2.6 6.1 23.2 1.0 1 0 0 1 1 1 0 Nop14-like family Cluap1 PF10234.9 CBY15070.1 - 1.8e-69 234.1 5.7 2.2e-69 233.9 5.7 1.0 1 0 0 1 1 1 1 Clusterin-associated protein-1 HsbA PF12296.8 CBY15070.1 - 0.011 16.1 0.6 0.016 15.6 0.6 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Serine_rich PF08824.10 CBY15070.1 - 0.014 15.4 2.8 0.025 14.6 2.8 1.4 1 0 0 1 1 1 0 Serine rich protein interaction domain TFR_dimer PF04253.15 CBY15070.1 - 0.022 14.9 0.4 0.049 13.7 0.4 1.6 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain IFT57 PF10498.9 CBY15070.1 - 0.023 13.7 4.6 0.025 13.6 3.5 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF3450 PF11932.8 CBY15070.1 - 0.06 12.7 6.6 0.1 11.9 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NleF_casp_inhib PF16809.5 CBY15070.1 - 0.066 13.1 3.0 1.1 9.2 1.8 2.7 1 1 0 2 2 2 0 NleF caspase inhibitor mCpol PF18182.1 CBY15070.1 - 0.091 13.1 1.2 4.8 7.5 0.0 2.3 1 1 0 2 2 2 0 minimal CRISPR polymerase domain DUF4407 PF14362.6 CBY15070.1 - 0.19 11.0 5.8 0.28 10.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CBY15070.1 - 0.32 9.8 7.7 0.51 9.2 7.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 CBY15070.1 - 0.33 11.9 7.9 0.46 11.4 6.9 1.8 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Spc24 PF08286.11 CBY15070.1 - 0.56 10.5 5.8 0.27 11.5 0.7 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PIN_8 PF18476.1 CBY15070.1 - 2.4 7.9 7.1 2.1 8.1 5.3 1.8 1 1 1 2 2 2 0 PIN like domain CENP-H PF05837.12 CBY15070.1 - 3 8.3 9.3 2.2 8.7 6.0 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 CBY15070.1 - 3.2 8.3 8.3 6.3 7.3 2.6 2.5 2 1 0 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 CBY15070.1 - 3.8 7.6 10.0 25 5.0 0.1 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CorA PF01544.18 CBY15071.1 - 0.081 12.2 0.1 0.093 12.0 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1828 PF08861.10 CBY15071.1 - 0.14 12.4 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF1828 STAT_bind PF02864.15 CBY15072.1 - 0.093 13.3 0.3 0.39 11.3 0.3 1.9 2 0 0 2 2 2 0 STAT protein, DNA binding domain CorA PF01544.18 CBY15072.1 - 0.12 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RVT_1 PF00078.27 CBY15073.1 - 6.5e-12 45.4 0.5 2.1e-11 43.8 0.2 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CBY15073.1 - 1.2e-09 38.1 0.0 4.6e-09 36.2 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY15073.1 - 4.2e-07 30.2 0.1 3.1e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY15073.1 - 3.1e-05 24.0 0.2 3.1e-05 24.0 0.2 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 CBY15073.1 - 0.0019 18.8 0.1 0.0046 17.6 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Rhomboid PF01694.22 CBY15075.1 - 1.1e-11 45.0 4.2 1.5e-11 44.6 4.2 1.1 1 0 0 1 1 1 1 Rhomboid family Pkinase PF00069.25 CBY15076.1 - 1e-05 25.1 0.1 1.1e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Ferlin_C PF16165.5 CBY15077.1 - 0.58 10.1 5.5 8.6 6.3 5.6 2.3 1 1 0 1 1 1 0 Ferlin C-terminus RNA_pol PF00940.19 CBY15079.1 - 3.3e-92 309.5 0.0 3.8e-92 309.3 0.0 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase zf-H2C2_2 PF13465.6 CBY15080.1 - 0.00022 21.5 4.6 0.00022 21.5 4.6 5.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY15080.1 - 0.00036 20.8 37.1 0.2 12.2 1.9 6.2 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CBY15080.1 - 0.0072 16.1 1.1 0.0072 16.1 1.1 5.3 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBY15080.1 - 0.009 16.8 35.6 1.1 10.2 1.9 5.8 5 0 0 5 5 5 3 C2H2-type zinc finger RRM_1 PF00076.22 CBY15081.1 - 2.5e-15 56.0 0.0 5.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY15081.1 - 8.4e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF5314 PF17241.2 CBY15087.1 - 0.0015 18.2 0.2 0.0018 18.0 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5314) HMMR_C PF15908.5 CBY15087.1 - 0.032 14.5 0.9 0.043 14.1 0.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal OPA3 PF07047.12 CBY15087.1 - 0.034 13.9 0.1 0.061 13.1 0.0 1.7 1 1 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Phyto_Pns9_10 PF05878.11 CBY15087.1 - 0.062 12.4 0.1 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 SGL PF08450.12 CBY15088.1 - 5e-35 121.3 0.3 6.2e-35 121.0 0.3 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 CBY15088.1 - 7.8e-05 22.7 0.0 0.02 15.0 0.0 3.4 2 1 0 2 2 2 1 Strictosidine synthase NHL PF01436.21 CBY15088.1 - 0.00038 20.3 3.6 2.4 8.3 0.0 4.6 5 0 0 5 5 5 2 NHL repeat Kelch_6 PF13964.6 CBY15088.1 - 0.039 14.2 0.6 21 5.6 0.1 3.9 3 0 0 3 3 3 0 Kelch motif SBBP PF06739.11 CBY15088.1 - 0.046 13.7 0.7 2.5 8.2 0.5 2.6 2 0 0 2 2 2 0 Beta-propeller repeat Reg_prop PF07494.11 CBY15088.1 - 0.074 13.3 0.2 8.5 7.0 0.0 3.6 2 1 1 3 3 3 0 Two component regulator propeller SMG1_N PF17229.2 CBY15088.1 - 0.17 12.6 0.0 0.32 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine/threonine-protein kinase SMG1 N-terminal FG-GAP PF01839.23 CBY15091.1 - 1.9e-12 47.1 3.3 2e-07 31.0 0.0 3.1 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.6 CBY15091.1 - 2.4e-06 28.0 5.6 9.3e-05 22.9 2.8 2.5 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EGF_3 PF12947.7 CBY15092.1 - 2.6e-09 37.1 24.2 5.4e-06 26.5 7.8 2.2 2 0 0 2 2 2 2 EGF domain EGF_2 PF07974.13 CBY15092.1 - 9.5e-05 22.7 18.7 0.003 17.9 8.3 2.9 1 1 2 3 3 3 2 EGF-like domain EGF PF00008.27 CBY15092.1 - 0.00083 19.6 18.0 0.0081 16.4 7.2 2.8 2 1 0 2 2 2 2 EGF-like domain EGF_CA PF07645.15 CBY15092.1 - 0.025 14.8 21.1 0.027 14.7 5.8 2.5 1 1 2 3 3 3 0 Calcium-binding EGF domain cEGF PF12662.7 CBY15092.1 - 0.052 13.5 8.1 0.98 9.4 2.9 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY15092.1 - 0.056 13.5 5.8 0.056 13.5 5.8 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY15092.1 - 0.41 11.0 15.2 0.18 12.1 2.4 2.3 2 0 0 2 2 2 0 Pvs28 EGF domain Antimicrobial25 PF16839.5 CBY15092.1 - 2.9 8.0 13.8 0.11 12.5 4.6 2.3 1 1 1 2 2 2 0 Nematode antimicrobial peptide GDPD PF03009.17 CBY15093.1 - 2.3e-08 34.1 0.1 9.6e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family PAP1 PF08601.10 CBY15093.1 - 1 9.0 12.7 1.4 8.6 12.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 CytochromB561_N PF09786.9 CBY15093.1 - 1.1 8.2 11.0 1.6 7.7 11.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Cwf_Cwc_15 PF04889.12 CBY15095.1 - 0.027 14.2 0.3 0.037 13.8 0.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PgaD PF13994.6 CBY15095.1 - 0.069 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein zf-RING_5 PF14634.6 CBY15097.1 - 2.2e-05 24.3 11.5 2.2e-05 24.3 11.5 2.5 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY15097.1 - 2.9e-05 24.3 10.5 2.9e-05 24.3 10.5 2.6 2 1 0 2 2 1 1 Ring finger domain ZapB PF06005.12 CBY15097.1 - 0.0034 17.8 6.0 0.0034 17.8 6.0 2.3 2 0 0 2 2 2 1 Cell division protein ZapB bZIP_1 PF00170.21 CBY15097.1 - 0.0092 16.1 6.8 0.0092 16.1 6.8 2.2 3 0 0 3 3 2 1 bZIP transcription factor DUF3584 PF12128.8 CBY15097.1 - 0.0097 13.5 6.4 0.012 13.1 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) zf-C3HC4 PF00097.25 CBY15097.1 - 0.023 14.6 11.6 0.023 14.6 11.6 2.8 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY15097.1 - 0.033 14.0 10.8 0.033 14.0 10.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Exonuc_VII_L PF02601.15 CBY15097.1 - 0.034 13.7 2.3 0.046 13.3 2.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MLD PF11647.8 CBY15097.1 - 0.036 14.4 0.5 0.24 11.7 0.8 2.1 2 0 0 2 2 2 0 Membrane Localization Domain KASH_CCD PF14662.6 CBY15097.1 - 0.078 12.8 15.8 0.14 12.0 14.8 1.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 CBY15097.1 - 0.1 13.2 12.0 0.04 14.6 8.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 CBY15097.1 - 1 9.2 8.0 0.11 12.2 2.8 2.1 2 0 0 2 2 2 0 Septum formation initiator DHR10 PF18595.1 CBY15097.1 - 1.1 9.3 13.8 2.6 8.1 12.3 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain zf-RING_6 PF14835.6 CBY15097.1 - 4 7.4 11.0 0.3 11.0 4.2 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FlaC_arch PF05377.11 CBY15097.1 - 4.1 7.9 13.6 0.2 12.1 5.6 2.6 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Synaptobrevin PF00957.21 CBY15097.1 - 8 6.3 10.0 5.5 6.9 6.4 2.4 2 1 1 3 3 3 0 Synaptobrevin Kelch_6 PF13964.6 CBY15098.1 - 0.079 13.3 6.9 0.49 10.8 0.0 4.0 3 1 1 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CBY15098.1 - 0.51 10.4 4.6 15 5.7 0.0 3.7 4 1 0 4 4 4 0 Kelch motif Pkinase PF00069.25 CBY15100.1 - 1.7e-09 37.5 0.2 1.7e-09 37.5 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15100.1 - 1.1e-05 24.9 0.0 2.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Homeodomain PF00046.29 CBY15102.1 - 4.9e-19 67.9 2.9 8.1e-19 67.2 2.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY15102.1 - 0.0012 18.7 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain DUF3481 PF11980.8 CBY15102.1 - 0.045 13.4 0.0 0.085 12.6 0.0 1.5 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein G-alpha PF00503.20 CBY15103.1 - 2.5e-121 405.2 5.9 2.9e-121 405.0 5.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY15103.1 - 1.9e-16 60.0 0.1 1.4e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY15103.1 - 6.6e-05 22.4 0.9 0.18 11.2 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CBY15103.1 - 0.0002 21.6 0.6 0.51 10.6 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CBY15103.1 - 0.006 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein MMR_HSR1 PF01926.23 CBY15103.1 - 0.0078 16.3 0.0 0.33 11.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 CBY15103.1 - 0.033 13.8 0.7 2.4 7.7 0.3 2.4 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 CBY15103.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBY15103.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IF-2B PF01008.17 CBY15104.1 - 1.2e-45 155.9 1.3 2.3e-45 155.0 1.3 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family PNK3P PF08645.11 CBY15105.1 - 9.7e-45 152.2 0.1 2.8e-44 150.6 0.0 1.8 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CBY15105.1 - 4.6e-10 39.8 0.0 0.0004 20.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain tRNA_lig_kinase PF08303.11 CBY15105.1 - 1.9e-05 24.8 0.3 5.6e-05 23.3 0.0 1.9 3 0 0 3 3 1 1 tRNA ligase kinase domain KTI12 PF08433.10 CBY15105.1 - 8.7e-05 22.1 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CBY15105.1 - 0.00032 21.2 0.1 0.004 17.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBY15105.1 - 0.00069 19.9 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Hydrolase PF00702.26 CBY15105.1 - 0.0013 19.1 0.0 0.0047 17.3 0.0 1.9 2 0 0 2 2 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY15105.1 - 0.0018 18.3 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Rad17 PF03215.15 CBY15105.1 - 0.0029 17.5 0.2 0.017 15.1 0.1 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CBY15105.1 - 0.0039 17.6 0.0 0.009 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CBY15105.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBY15105.1 - 0.0078 16.3 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 CBY15105.1 - 0.021 14.6 0.1 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase HAD_2 PF13419.6 CBY15105.1 - 0.024 14.7 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RNA_helicase PF00910.22 CBY15105.1 - 0.025 15.0 0.0 0.084 13.3 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Hydrolase_6 PF13344.6 CBY15105.1 - 0.03 14.4 0.0 3.9 7.7 0.0 3.0 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase AAA PF00004.29 CBY15105.1 - 0.058 13.8 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CBY15105.1 - 0.062 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 CBY15105.1 - 0.071 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 CBY15105.1 - 0.078 12.2 0.0 0.35 10.1 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_24 PF13479.6 CBY15105.1 - 0.084 12.6 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CBY15105.1 - 0.09 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 CBY15105.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 CBY15105.1 - 0.16 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CBY15105.1 - 0.18 12.1 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY15105.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY15105.1 - 0.18 11.6 0.2 6.2 6.6 0.0 2.9 2 1 1 3 3 3 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CBY15105.1 - 0.2 11.0 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UPF0139 PF03669.13 CBY15106.1 - 2.3e-42 142.8 2.8 2.5e-42 142.7 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) NT5C PF06941.12 CBY15106.1 - 0.11 12.3 0.0 0.4 10.5 0.0 1.7 1 1 1 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NDK PF00334.19 CBY15108.1 - 1.3e-51 174.2 0.0 1.5e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase EF-hand_6 PF13405.6 CBY15109.1 - 1.9e-12 46.1 0.8 1.4e-06 27.7 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBY15109.1 - 3.4e-11 41.9 0.3 4.3e-05 22.8 0.0 3.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY15109.1 - 1.3e-08 35.2 0.5 0.001 19.5 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY15109.1 - 0.00025 20.4 3.5 0.00062 19.1 0.1 3.0 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 CBY15109.1 - 0.045 14.1 0.0 0.34 11.2 0.0 2.3 2 1 1 3 3 3 0 EF-hand domain ANAPC5 PF12862.7 CBY15109.1 - 0.05 13.7 0.1 0.09 12.9 0.0 1.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 EF-hand_8 PF13833.6 CBY15109.1 - 0.086 12.7 0.9 1.9 8.4 0.0 2.8 3 1 1 4 4 4 0 EF-hand domain pair HORMA PF02301.18 CBY15110.1 - 1.5e-13 50.9 0.2 2e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 CBY15110.1 - 0.00095 19.0 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial HORMA domain 2 Lectin_C PF00059.21 CBY15114.1 - 6.3e-06 26.9 2.3 1.2e-05 25.9 1.0 2.0 2 1 0 2 2 2 1 Lectin C-type domain 5_3_exonuc_N PF02739.16 CBY15114.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain SSF PF00474.17 CBY15115.1 - 1.3e-11 44.0 8.5 2.2e-11 43.2 8.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF5056 PF16479.5 CBY15115.1 - 0.29 11.4 1.8 0.54 10.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) CitMHS PF03600.16 CBY15116.1 - 0.65 9.1 24.4 11 5.1 24.3 2.1 1 1 0 1 1 1 0 Citrate transporter DUF5056 PF16479.5 CBY15117.1 - 0.14 12.4 2.0 0.19 12.0 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5056) CitMHS PF03600.16 CBY15118.1 - 0.65 9.1 24.4 11 5.1 24.3 2.1 1 1 0 1 1 1 0 Citrate transporter HHH_4 PF14490.6 CBY15119.1 - 0.045 13.7 0.1 0.098 12.7 0.0 1.6 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain Fer2_BFD PF04324.15 CBY15119.1 - 0.13 12.7 0.1 74 3.8 0.0 3.3 3 0 0 3 3 3 0 BFD-like [2Fe-2S] binding domain EGF PF00008.27 CBY15121.1 - 1.2e-21 76.7 56.9 3.5e-07 30.4 5.9 6.0 6 0 0 6 6 6 4 EGF-like domain hEGF PF12661.7 CBY15121.1 - 4.1e-10 39.9 46.3 0.00021 21.8 2.7 5.6 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_3 PF12947.7 CBY15121.1 - 5.3e-08 32.9 39.7 0.00053 20.1 5.3 5.4 4 1 1 5 5 5 3 EGF domain cEGF PF12662.7 CBY15121.1 - 0.00094 19.1 30.0 0.12 12.3 5.2 4.1 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_2 PF07974.13 CBY15121.1 - 0.1 13.0 59.9 0.14 12.5 10.4 5.4 5 0 0 5 5 5 0 EGF-like domain FXa_inhibition PF14670.6 CBY15121.1 - 0.91 9.9 49.3 1.9 8.8 9.2 5.6 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site SOG2 PF10428.9 CBY15121.1 - 2.1 7.5 34.9 3.2 6.9 34.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Kelch_2 PF07646.15 CBY15122.1 - 3.9e-05 23.4 4.3 0.18 11.8 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY15122.1 - 0.023 15.0 4.6 1.4 9.3 0.0 4.0 4 0 0 4 4 4 0 Kelch motif DUF3326 PF11805.8 CBY15122.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Kelch_4 PF13418.6 CBY15122.1 - 0.13 12.3 2.9 11 6.1 0.1 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY15122.1 - 0.19 11.8 0.1 0.19 11.8 0.1 3.4 3 0 0 3 3 3 0 Kelch motif PSS PF03034.15 CBY15123.1 - 8.4e-101 337.3 20.5 1.2e-100 336.8 20.5 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase LapA_dom PF06305.11 CBY15123.1 - 0.23 11.3 4.2 0.79 9.6 0.2 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1129 PF06570.11 CBY15123.1 - 0.35 10.3 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Hydrolase_6 PF13344.6 CBY15124.1 - 1.2e-16 60.6 0.0 5.7e-14 52.1 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY15124.1 - 0.0016 18.8 0.1 0.0042 17.4 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.26 CBY15126.1 - 8.8e-10 38.5 18.8 0.00013 22.2 0.3 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CBY15126.1 - 1.2e-09 37.8 11.7 1.6e-08 34.2 0.2 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 CBY15126.1 - 4.2e-09 36.5 17.8 0.00085 20.0 0.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY15126.1 - 3.4e-08 33.3 17.7 0.00016 21.6 0.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CBY15126.1 - 4.9e-08 33.1 14.6 8.6e-06 26.0 1.8 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY15126.1 - 4e-05 23.8 2.5 4e-05 23.8 2.5 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding C1_2 PF03107.16 CBY15126.1 - 0.00014 22.1 2.7 1.6 9.1 0.0 3.3 3 0 0 3 3 3 2 C1 domain zf-C2H2_2 PF12756.7 CBY15126.1 - 0.0011 19.3 14.3 0.029 14.7 7.0 2.7 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 CBY15126.1 - 0.011 15.4 9.7 1.2 8.7 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 CBY15126.1 - 0.011 15.8 5.2 1.9 8.6 0.1 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 CBY15126.1 - 0.013 15.6 8.5 1.2 9.3 5.2 2.8 2 1 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 CBY15126.1 - 0.013 16.2 2.6 0.57 11.0 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon family zf-H2C2_2 PF13465.6 CBY15126.1 - 0.021 15.3 0.0 0.021 15.3 0.0 4.5 4 1 0 4 4 4 0 Zinc-finger double domain YhfH PF14149.6 CBY15126.1 - 0.038 14.0 0.0 0.038 14.0 0.0 2.4 3 0 0 3 3 3 0 YhfH-like protein Fer4_9 PF13187.6 CBY15126.1 - 0.044 14.0 1.9 0.45 10.7 1.1 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf_C2H2_ZHX PF18387.1 CBY15126.1 - 0.079 12.6 8.9 2.5 7.8 0.1 3.1 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DNA_RNApol_7kD PF03604.13 CBY15126.1 - 0.084 12.6 3.5 15 5.3 0.2 3.4 4 0 0 4 4 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_SprT PF17283.2 CBY15126.1 - 0.14 12.1 3.0 7.4 6.6 0.2 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain TFIIS_C PF01096.18 CBY15126.1 - 0.17 11.8 5.5 11 6.0 0.1 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-CHY PF05495.12 CBY15126.1 - 0.17 12.4 14.3 1.1 9.8 1.4 2.4 1 1 0 2 2 2 0 CHY zinc finger Actin_micro PF17003.5 CBY15126.1 - 0.19 10.8 16.1 4.5 6.3 1.2 3.0 1 1 1 2 2 2 0 Putative actin-like family zinc-ribbons_6 PF07191.12 CBY15126.1 - 0.26 11.3 7.5 4.5 7.3 0.1 2.4 2 1 0 2 2 2 0 zinc-ribbons Cobl PF09469.10 CBY15126.1 - 0.31 11.3 2.7 1.3 9.4 0.1 2.3 1 1 0 2 2 2 0 Cordon-bleu ubiquitin-like domain zf-C2HC_2 PF13913.6 CBY15126.1 - 0.48 10.4 7.8 6.6 6.8 0.0 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type HalOD2 PF18547.1 CBY15126.1 - 0.57 10.1 3.1 6 6.9 0.1 2.8 3 0 0 3 3 3 0 Halobacterial output domain 2 DZR PF12773.7 CBY15126.1 - 1 9.5 8.5 23 5.1 8.9 2.5 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 CBY15126.1 - 1.5 8.8 9.4 9.9 6.2 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 CBY15126.1 - 2.7 7.9 6.0 12 5.9 0.1 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) PSCyt3 PF07627.11 CBY15126.1 - 3.9 7.8 6.8 5.3 7.4 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) XPA_N PF01286.18 CBY15126.1 - 4 7.6 9.0 5.9 7.0 0.3 3.0 3 0 0 3 3 3 0 XPA protein N-terminal zf-3CxxC PF13695.6 CBY15126.1 - 5 7.6 9.0 3.5 8.1 0.3 2.7 2 1 0 2 2 2 0 Zinc-binding domain zf-LYAR PF08790.11 CBY15126.1 - 5.7 6.9 9.4 4.5 7.3 0.6 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Rubredoxin_2 PF18073.1 CBY15126.1 - 9.6 6.0 12.0 8.3 6.2 0.7 3.2 3 0 0 3 3 3 0 Rubredoxin metal binding domain SDA1 PF05285.12 CBY15129.1 - 0.0048 16.4 0.9 0.0048 16.4 0.9 1.6 2 0 0 2 2 2 1 SDA1 DUF3810 PF12725.7 CBY15129.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF818 PF05677.12 CBY15129.1 - 0.067 12.1 0.4 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) EphA2_TM PF14575.6 CBY15129.1 - 0.32 11.9 1.7 2.4 9.1 0.0 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain I-set PF07679.16 CBY15131.1 - 4e-13 49.2 0.0 5.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY15131.1 - 7.8e-13 48.8 0.3 1.1e-12 48.3 0.3 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY15131.1 - 7.3e-07 29.4 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY15131.1 - 9e-07 29.0 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CBY15131.1 - 0.0023 18.1 0.1 0.19 11.9 0.1 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain NDUF_C2 PF06374.11 CBY15131.1 - 0.0091 16.1 0.0 0.025 14.7 0.0 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Baculo_11_kDa PF06143.11 CBY15131.1 - 0.041 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Izumo-Ig PF16706.5 CBY15131.1 - 0.07 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain AARP2CN PF08142.12 CBY15132.1 - 2.3e-08 34.0 0.5 7.6e-07 29.1 0.1 2.5 2 0 0 2 2 2 1 AARP2CN (NUC121) domain DNA_pol_phi PF04931.13 CBY15132.1 - 6.1 4.8 22.1 7.6 4.5 22.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi VWD PF00094.25 CBY15138.1 - 6.2e-29 101.3 11.0 2.8e-17 63.4 2.2 3.9 3 0 0 3 3 3 3 von Willebrand factor type D domain Lectin_C PF00059.21 CBY15138.1 - 1.3e-07 32.3 0.1 1.3e-07 32.3 0.1 2.3 2 0 0 2 2 2 1 Lectin C-type domain TIL PF01826.17 CBY15138.1 - 2.1e-07 31.1 30.5 3.2e-06 27.3 13.6 8.4 8 0 0 8 8 8 3 Trypsin Inhibitor like cysteine rich domain C8 PF08742.11 CBY15138.1 - 7e-07 29.6 11.3 4.1e-05 23.9 1.7 6.8 5 2 2 7 7 7 2 C8 domain ShK PF01549.24 CBY15138.1 - 0.00079 19.9 11.0 0.00079 19.9 11.0 6.6 5 1 1 6 6 6 3 ShK domain-like Ephrin_rec_like PF07699.13 CBY15139.1 - 1.8e-06 27.6 25.3 0.00019 21.1 1.4 46.7 35 12 12 47 47 47 25 Putative ephrin-receptor like EGF_3 PF12947.7 CBY15141.1 - 0.00031 20.9 9.2 0.0006 20.0 9.2 1.5 1 0 0 1 1 1 1 EGF domain EGF_MSP1_1 PF12946.7 CBY15141.1 - 0.014 15.4 6.2 0.026 14.6 6.2 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 CRAL_TRIO PF00650.20 CBY15145.1 - 9.5e-12 44.9 0.0 1.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBY15145.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CBY15146.1 - 0.00011 22.3 0.1 0.00031 20.9 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain LRR_8 PF13855.6 CBY15147.1 - 1.2e-31 108.3 20.0 8.2e-12 44.7 0.3 4.5 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY15147.1 - 6.8e-15 54.9 20.5 8.8e-06 26.0 0.1 6.1 3 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY15147.1 - 8e-09 35.5 1.7 0.00016 21.7 1.1 2.6 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY15147.1 - 9.6e-06 25.2 4.0 0.0018 17.8 1.3 2.6 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 CBY15147.1 - 2.4e-05 24.2 15.3 0.8 10.5 0.0 7.9 8 1 0 8 8 8 2 Leucine Rich Repeat VAR1 PF05316.12 CBY15147.1 - 0.0023 17.0 0.1 0.0039 16.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein (VAR1) LRR_6 PF13516.6 CBY15147.1 - 0.19 11.8 19.1 4 7.7 0.1 6.4 6 1 1 7 7 7 0 Leucine Rich repeat DUF1993 PF09351.10 CBY15148.1 - 0.15 12.2 1.7 0.3 11.2 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) MctB PF11382.8 CBY15148.1 - 0.24 11.0 3.1 0.4 10.3 3.1 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB AAA_21 PF13304.6 CBY15148.1 - 0.26 11.0 10.8 0.31 10.8 10.8 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Tho2 PF11262.8 CBY15148.1 - 6.4 5.9 7.9 0.26 10.5 2.4 1.4 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Nop25 PF09805.9 CBY15148.1 - 7.7 7.0 31.2 2.1 8.8 12.6 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) CRAL_TRIO PF00650.20 CBY15149.1 - 3.2e-17 62.7 0.1 5.1e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBY15149.1 - 0.064 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain PHD PF00628.29 CBY15150.1 - 1.2 9.1 18.7 0.034 14.0 11.4 2.3 2 0 0 2 2 2 0 PHD-finger FXMRP1_C_core PF12235.8 CBY15150.1 - 6.9 7.3 21.9 0.27 11.9 8.0 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal C2 PF00168.30 CBY15151.1 - 2.9e-12 46.8 0.0 5.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_Tyr PF07714.17 CBY15152.1 - 2.4e-41 141.7 0.0 3.6e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY15152.1 - 4.8e-40 137.6 0.0 8.3e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CBY15152.1 - 0.0011 18.3 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY15152.1 - 0.005 15.8 0.1 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBY15152.1 - 0.0055 16.7 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY15152.1 - 0.0073 15.1 0.7 0.016 14.0 0.7 1.4 1 1 0 1 1 1 1 Fungal protein kinase LINES_C PF14695.6 CBY15152.1 - 1.3 8.6 6.1 0.28 10.7 0.2 3.0 3 0 0 3 3 3 0 Lines C-terminus CLTH PF10607.9 CBY15153.1 - 3.2e-10 40.1 1.9 4.6e-10 39.6 1.9 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CBY15153.1 - 0.00014 21.8 0.2 0.00037 20.5 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_7 PF02591.15 CBY15153.1 - 0.045 14.0 0.8 2.6 8.3 0.1 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain PyrI_C PF02748.15 CBY15153.1 - 0.079 12.9 0.8 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CSTF1_dimer PF16699.5 CBY15153.1 - 0.081 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain CTU2 PF10288.9 CBY15153.1 - 0.33 11.2 2.3 0.51 10.6 0.1 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-RING_2 PF13639.6 CBY15153.1 - 0.36 11.2 2.3 0.49 10.8 0.4 2.2 2 0 0 2 2 2 0 Ring finger domain zf-H2C2_2 PF13465.6 CBY15153.1 - 0.87 10.1 3.1 0.84 10.2 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger double domain G-patch PF01585.23 CBY15154.1 - 6.5e-13 48.3 0.8 1.7e-12 47.0 0.8 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CBY15155.1 - 0.00019 21.2 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_11 PF08241.12 CBY15156.1 - 2.5e-16 60.1 0.0 3.4e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY15156.1 - 1.7e-09 38.3 0.0 3e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY15156.1 - 3.6e-09 36.7 0.0 4e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY15156.1 - 2.7e-08 33.8 0.0 8.1e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY15156.1 - 2.5e-07 31.4 0.0 4.6e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY15156.1 - 4.9e-06 26.0 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CBY15156.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.12 CBY15156.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 CBY15156.1 - 0.019 13.6 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF924 PF06041.11 CBY15156.1 - 0.18 11.9 0.0 0.23 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Vps55 PF04133.14 CBY15157.1 - 6.8e-34 116.3 6.2 7.8e-34 116.1 6.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 LSM PF01423.22 CBY15159.1 - 1.1e-13 50.6 0.1 1.3e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain PDEase_I PF00233.19 CBY15160.1 - 1.5e-41 142.7 5.5 2.1e-41 142.2 5.5 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Macscav_rec PF03523.13 CBY15160.1 - 0.041 13.8 2.9 0.047 13.6 0.4 2.2 2 0 0 2 2 2 0 Macrophage scavenger receptor UPF0242 PF06785.11 CBY15163.1 - 9.8e-05 22.5 0.8 0.00016 21.8 0.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Kelch_5 PF13854.6 CBY15163.1 - 0.0023 17.9 0.8 0.12 12.4 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Cep57_CLD_2 PF14197.6 CBY15163.1 - 0.0037 17.3 7.9 0.015 15.3 5.1 2.2 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 Leu_zip PF15294.6 CBY15163.1 - 0.009 15.6 0.6 0.014 14.9 0.6 1.2 1 0 0 1 1 1 1 Leucine zipper Kelch_6 PF13964.6 CBY15163.1 - 0.023 15.0 0.4 1.7 9.1 0.0 3.7 4 1 0 4 4 4 0 Kelch motif SHE3 PF17078.5 CBY15163.1 - 0.033 13.9 1.1 0.053 13.2 1.1 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Geminin PF07412.12 CBY15163.1 - 4.3 7.0 7.5 8 6.1 7.5 1.3 1 0 0 1 1 1 0 Geminin Astacin PF01400.24 CBY15164.1 - 7.4e-27 94.2 2.4 8.4e-27 94.0 0.4 2.2 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) zf-RING_UBOX PF13445.6 CBY15164.1 - 1e-05 25.4 3.2 1e-05 25.4 3.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY15164.1 - 4.1e-05 23.8 11.9 0.00011 22.5 7.2 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CBY15164.1 - 0.00011 22.1 9.8 0.00066 19.6 6.0 2.7 2 0 0 2 2 2 1 zinc-RING finger domain Macoilin PF09726.9 CBY15164.1 - 0.00053 18.7 8.1 0.00083 18.1 8.1 1.2 1 0 0 1 1 1 1 Macoilin family zf-C3HC4_2 PF13923.6 CBY15164.1 - 0.0016 18.2 14.4 0.0084 15.9 10.1 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY15164.1 - 0.0025 17.7 9.1 0.0025 17.7 9.1 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY15164.1 - 0.0076 16.1 15.9 0.019 14.8 10.2 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 CBY15164.1 - 0.0085 16.0 5.4 0.0085 16.0 5.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY15164.1 - 0.014 15.2 9.7 0.5 10.2 6.3 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Mucin PF01456.17 CBY15164.1 - 0.036 14.1 49.3 0.065 13.2 49.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Rad50_zn_hook PF04423.14 CBY15164.1 - 0.043 13.7 3.2 0.098 12.5 0.1 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 CBY15164.1 - 0.046 13.6 16.2 6.9 6.6 0.1 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 IBR PF01485.21 CBY15164.1 - 0.088 13.0 11.6 0.18 12.1 6.5 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-rbx1 PF12678.7 CBY15164.1 - 0.73 10.2 10.5 0.74 10.1 3.2 2.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_Tnp_IS91 PF14319.6 CBY15164.1 - 0.74 9.9 8.5 1.2 9.3 3.6 2.8 2 0 0 2 2 2 0 Transposase zinc-binding domain Golgin_A5 PF09787.9 CBY15164.1 - 0.99 8.8 14.8 2.6 7.4 14.8 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 FliT PF05400.13 CBY15164.1 - 1.9 9.3 10.8 2.5 9.0 4.6 2.7 2 0 0 2 2 2 0 Flagellar protein FliT FSA_C PF10479.9 CBY15164.1 - 2.5 6.1 19.0 3.6 5.6 19.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FYVE PF01363.21 CBY15164.1 - 2.5 8.3 10.4 5.8 7.1 5.2 2.5 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 CBY15164.1 - 3.1 8.0 8.9 4.4 7.6 6.1 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING CENP-H PF05837.12 CBY15164.1 - 3.3 8.2 14.4 0.3 11.5 8.2 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) zf-RING_11 PF17123.5 CBY15164.1 - 3.3 7.5 10.9 8.8 6.2 10.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-C2H2_jaz PF12171.8 CBY15164.1 - 3.5 8.0 6.0 4.3 7.7 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF1664 PF07889.12 CBY15164.1 - 3.7 7.6 8.3 9.7 6.3 7.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AJAP1_PANP_C PF15298.6 CBY15164.1 - 4.3 7.5 25.7 2.1 8.5 23.2 1.7 2 0 0 2 2 1 0 AJAP1/PANP C-terminus Zn-C2H2_12 PF18112.1 CBY15164.1 - 9.9 6.7 8.6 30 5.2 0.5 3.0 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain KH_1 PF00013.29 CBY15165.1 - 6.1e-35 118.9 7.9 3.6e-13 49.1 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CBY15165.1 - 2.9e-10 39.8 5.7 0.0022 17.8 0.4 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CBY15165.1 - 2.8e-08 33.5 1.7 0.08 12.8 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CBY15165.1 - 0.0017 18.4 4.7 1.7 8.8 0.1 3.6 4 0 0 4 4 4 2 NusA-like KH domain PEGA PF08308.11 CBY15165.1 - 0.075 12.9 0.1 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 PEGA domain zf-C2H2 PF00096.26 CBY15167.1 - 0.00027 21.2 42.6 0.0028 18.0 0.9 6.9 7 1 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY15167.1 - 0.0015 19.2 0.7 0.0015 19.2 0.7 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.7 CBY15167.1 - 0.0022 18.3 4.6 0.0062 16.9 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 CBY15167.1 - 0.0022 17.6 0.2 0.0022 17.6 0.2 4.8 3 1 2 5 5 5 1 Zinc-fingers and homeoboxes C2H2 finger domain A2L_zn_ribbon PF08792.10 CBY15167.1 - 0.0044 16.7 0.1 0.0044 16.7 0.1 3.0 3 0 0 3 3 3 1 A2L zinc ribbon domain zf-C2H2_jaz PF12171.8 CBY15167.1 - 0.011 16.0 0.9 0.011 16.0 0.9 3.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding NID PF07292.13 CBY15167.1 - 0.025 15.2 0.4 1.8 9.2 0.0 3.0 2 1 0 3 3 3 0 Nmi/IFP 35 domain (NID) zf-C2H2_11 PF16622.5 CBY15167.1 - 0.032 14.0 0.2 0.032 14.0 0.2 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY15167.1 - 0.032 14.2 0.3 0.032 14.2 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CBY15167.1 - 1 9.4 0.1 1 9.4 0.1 3.6 3 1 0 3 3 3 0 zinc-finger of a C2HC-type FH2 PF02181.23 CBY15168.1 - 4.5e-36 124.8 0.2 5.1e-36 124.6 0.2 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain SH3_9 PF14604.6 CBY15169.1 - 8.3e-37 124.8 0.1 6.2e-14 51.6 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 CBY15169.1 - 2.7e-33 113.3 0.4 2e-11 43.3 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBY15169.1 - 8.2e-31 105.5 0.6 3.1e-13 49.2 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain Peroxin-3 PF04882.12 CBY15170.1 - 0.1 11.6 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Peroxin-3 Sulfotransfer_2 PF03567.14 CBY15171.1 - 4.5e-13 49.7 0.0 6.1e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family zf-C3HC4_3 PF13920.6 CBY15173.1 - 1.6e-09 37.5 8.2 2.4e-09 36.9 8.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY15173.1 - 8.2e-09 35.3 10.3 1.3e-08 34.6 10.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY15173.1 - 1e-07 32.2 10.2 1.6e-07 31.5 10.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY15173.1 - 4.8e-07 29.5 7.1 3.8e-06 26.7 7.0 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY15173.1 - 2.8e-06 27.2 9.1 6.1e-05 23.0 2.9 2.3 2 0 0 2 2 2 2 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY15173.1 - 1.6e-05 24.7 7.6 3.9e-05 23.4 7.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY15173.1 - 3.4e-05 23.6 8.6 6.5e-05 22.7 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY15173.1 - 6.4e-05 22.7 7.8 0.0001 22.0 7.8 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.21 CBY15173.1 - 0.00024 21.2 10.4 0.00048 20.2 5.2 2.4 1 1 1 2 2 2 1 FYVE zinc finger Baculo_IE-1 PF05290.11 CBY15173.1 - 0.0022 18.0 6.4 0.0028 17.6 6.4 1.4 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_11 PF17123.5 CBY15173.1 - 0.0028 17.4 10.8 0.023 14.4 5.4 2.5 2 0 0 2 2 2 1 RING-like zinc finger DUF1635 PF07795.11 CBY15173.1 - 0.033 14.1 3.5 0.034 14.0 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Rtf2 PF04641.12 CBY15173.1 - 0.06 12.7 18.7 0.62 9.4 18.5 1.9 1 1 0 1 1 1 0 Rtf2 RING-finger DUF2256 PF10013.9 CBY15173.1 - 0.078 13.1 1.8 0.078 13.1 1.8 2.7 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_6 PF13912.6 CBY15173.1 - 0.1 12.6 7.6 2.3 8.3 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Prok-RING_1 PF14446.6 CBY15173.1 - 0.19 11.6 11.2 0.93 9.5 0.2 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 CBY15173.1 - 0.3 11.3 11.1 1.4e+02 2.8 12.5 3.1 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 CBY15173.1 - 0.57 10.1 0.0 0.57 10.1 0.0 4.5 3 1 2 5 5 5 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 CBY15173.1 - 0.89 10.6 9.7 1.9 9.6 0.1 3.0 2 1 1 3 3 2 0 C2H2-type zinc finger TALPID3 PF15324.6 CBY15173.1 - 2 6.0 6.1 2.2 5.9 6.1 1.0 1 0 0 1 1 1 0 Hedgehog signalling target UBZ_FAAP20 PF15750.5 CBY15173.1 - 3.1 7.8 5.3 8.5 6.4 1.4 2.9 2 1 0 2 2 2 0 Ubiquitin-binding zinc-finger OmpH PF03938.14 CBY15173.1 - 3.9 7.8 12.5 4.8 7.5 12.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 CBY15174.1 - 1.4 7.4 8.3 2.3 6.6 8.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family IRK PF01007.20 CBY15178.1 - 6.6e-49 165.4 2.3 8.3e-49 165.0 2.3 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 CBY15178.1 - 1.7e-13 50.6 0.1 2.5e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 CBY15178.1 - 0.11 12.5 12.7 0.49 10.4 12.7 1.9 1 1 0 1 1 1 0 Ion channel Kelch_5 PF13854.6 CBY15179.1 - 0.011 15.7 0.1 0.28 11.2 0.0 2.7 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 CBY15179.1 - 0.017 15.4 4.3 0.18 12.2 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CBY15179.1 - 0.048 13.7 0.5 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif DUF962 PF06127.11 CBY15181.1 - 0.46 10.6 7.4 1.8 8.7 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Exo_endo_phos_2 PF14529.6 CBY15182.1 - 0.0039 17.0 5.9 0.0072 16.2 0.1 3.7 3 1 1 4 4 4 1 Endonuclease-reverse transcriptase DUF1773 PF08593.10 CBY15182.1 - 0.086 13.9 0.1 0.84 10.7 0.1 2.9 1 0 0 1 1 1 0 Domain of unknown function DUF2526 PF10735.9 CBY15182.1 - 0.09 12.9 0.6 0.42 10.8 0.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) SlyX PF04102.12 CBY15182.1 - 0.99 10.1 4.8 8.4 7.1 4.8 2.7 1 0 0 1 1 1 0 SlyX Carboxyl_trans PF01039.22 CBY15185.1 - 2e-36 125.7 0.0 2.2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain UDPGT PF00201.18 CBY15187.1 - 2.4e-120 402.7 0.6 2.7e-120 402.5 0.6 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CBY15187.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain HECT PF00632.25 CBY15188.1 - 1.4e-95 320.3 0.0 1.8e-95 319.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CBY15188.1 - 6.1e-07 29.4 0.1 1.4e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 WW domain Rieske PF00355.26 CBY15189.1 - 5.1e-12 45.6 0.1 8.2e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.14 CBY15189.1 - 2.4e-09 36.9 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY15189.1 - 2e-05 23.9 0.6 2.7e-05 23.5 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CBY15189.1 - 6.9e-05 22.2 0.2 9.7e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CBY15189.1 - 0.00025 19.9 2.0 0.0004 19.2 2.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 CBY15189.1 - 0.00037 20.7 0.8 0.00074 19.7 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBY15189.1 - 0.00056 19.1 0.2 0.00073 18.7 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CBY15189.1 - 0.00065 19.1 0.0 0.00088 18.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBY15189.1 - 0.00091 19.7 0.1 0.0022 18.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CBY15189.1 - 0.0014 19.0 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 CBY15189.1 - 0.003 16.9 0.1 0.0042 16.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CBY15189.1 - 0.003 17.2 1.1 0.0048 16.5 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CBY15189.1 - 0.0078 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 CBY15189.1 - 0.0097 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 CBY15189.1 - 0.015 14.4 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein IlvN PF07991.12 CBY15189.1 - 0.036 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 CBY15189.1 - 0.086 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_tran_WecB PF03808.13 CBY15189.1 - 0.1 12.5 0.0 1.3 9.0 0.0 2.1 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Shikimate_DH PF01488.20 CBY15189.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 CBY15189.1 - 0.14 12.1 0.1 0.89 9.5 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 CBY15189.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 CBY15189.1 - 0.32 9.8 2.1 0.45 9.3 2.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 CBY15189.1 - 0.33 10.2 6.9 0.47 9.7 6.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Helicase_C PF00271.31 CBY15192.1 - 1.9e-17 63.6 0.0 3.1e-13 50.0 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 CBY15192.1 - 4.8e-16 59.0 0.0 8.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CBY15192.1 - 3e-08 34.3 7.9 8.4e-08 32.8 7.9 1.8 1 0 0 1 1 1 1 RecQ zinc-binding AAA_34 PF13872.6 CBY15192.1 - 0.00038 19.4 0.0 0.00077 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Apc15p PF05841.11 CBY15192.1 - 0.25 12.1 2.0 0.2 12.5 0.3 1.7 2 0 0 2 2 2 0 Apc15p protein Arg_decarbox_C PF17944.1 CBY15192.1 - 0.34 11.5 1.2 2.6 8.7 0.1 2.7 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension SRI PF08236.11 CBY15193.1 - 0.0004 20.5 1.9 0.0004 20.5 1.9 2.6 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WD40 PF00400.32 CBY15194.1 - 1.5e-17 63.6 0.0 4.4e-05 24.2 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY15194.1 - 4.4e-06 26.9 0.0 0.24 11.7 0.0 4.0 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY15194.1 - 0.001 18.1 0.1 0.41 9.5 0.0 2.9 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBY15194.1 - 0.0052 16.1 0.0 2.9 7.1 0.0 2.3 2 1 0 2 2 2 2 WD40-like domain DUF3686 PF12458.8 CBY15194.1 - 0.078 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 ATPase involved in DNA repair DDA1 PF10172.9 CBY15196.1 - 1.4e-20 73.3 0.9 2.1e-20 72.7 0.9 1.3 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase UvsY PF11056.8 CBY15196.1 - 0.022 15.1 0.8 0.037 14.4 0.8 1.4 1 1 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY AD PF09793.9 CBY15198.1 - 3.9e-15 55.8 0.4 5.6e-15 55.3 0.4 1.2 1 0 0 1 1 1 1 Anticodon-binding domain UPF0240 PF06784.11 CBY15199.1 - 1.3e-06 28.6 0.0 1.5e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) ELM2 PF01448.24 CBY15201.1 - 1.1e-08 35.6 0.2 2.7e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 CBY15201.1 - 4.5e-08 32.9 5.2 3.8e-05 23.5 0.2 2.7 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-binding PF00249.31 CBY15201.1 - 7.8e-06 26.0 0.1 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY15201.1 - 0.0032 17.7 0.4 0.023 15.0 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain End3 PF12761.7 CBY15201.1 - 0.027 14.6 0.3 0.051 13.7 0.3 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Snapin_Pallidin PF14712.6 CBY15201.1 - 0.035 14.5 0.5 0.089 13.2 0.5 1.7 1 0 0 1 1 1 0 Snapin/Pallidin Peptidase_M75 PF09375.10 CBY15201.1 - 0.13 11.7 0.3 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Imelysin XhlA PF10779.9 CBY15201.1 - 0.28 11.4 3.6 0.61 10.3 3.6 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Bap31_Bap29_C PF18035.1 CBY15201.1 - 0.37 10.8 2.7 1.1 9.3 2.7 1.9 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Longin PF13774.6 CBY15202.1 - 2e-25 88.6 0.9 3.6e-25 87.8 0.9 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CBY15202.1 - 8.2e-15 54.4 0.6 8.2e-15 54.4 0.6 1.6 2 0 0 2 2 2 1 Synaptobrevin Sec20 PF03908.13 CBY15202.1 - 0.29 11.1 4.6 0.15 12.0 1.9 2.0 2 1 0 2 2 2 0 Sec20 Ribosomal_S8e PF01201.22 CBY15203.1 - 3.9e-47 159.9 15.9 4.1e-46 156.5 15.9 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e Pannexin_like PF12534.8 CBY15203.1 - 7.6 5.5 7.3 11 5.0 7.3 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pkinase PF00069.25 CBY15204.1 - 1.6e-71 240.8 0.0 2e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15204.1 - 6.2e-31 107.6 0.1 8e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY15204.1 - 1.7e-08 34.1 0.1 3.2e-08 33.2 0.1 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CBY15204.1 - 7.1e-07 29.1 0.7 0.013 15.1 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBY15204.1 - 3.6e-06 26.0 0.1 8.5e-06 24.8 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY15204.1 - 7.5e-05 21.8 3.0 0.00021 20.4 3.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY15204.1 - 0.0018 18.2 0.1 0.016 15.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY15204.1 - 0.0019 17.6 0.9 0.0053 16.1 0.3 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rep_Org_C PF06926.11 CBY15204.1 - 0.035 14.4 0.1 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus Aa_trans PF01490.18 CBY15205.1 - 1.1e-21 77.0 36.1 2.2e-21 76.0 36.1 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein CopD PF05425.13 CBY15205.1 - 0.004 17.5 0.3 0.004 17.5 0.3 2.6 2 1 0 2 2 2 1 Copper resistance protein D DUF4267 PF14087.6 CBY15205.1 - 0.013 15.6 4.5 0.095 12.8 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4267) CDO_I PF05995.12 CBY15206.1 - 0.092 12.1 0.2 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Cysteine dioxygenase type I AAA_6 PF12774.7 CBY15208.1 - 6.6e-143 475.6 0.0 1.3e-141 471.3 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 CBY15208.1 - 9.3e-93 310.8 0.2 2.2e-92 309.6 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBY15208.1 - 1.9e-89 299.5 0.0 4.1e-89 298.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBY15208.1 - 9.7e-84 279.9 1.2 9.7e-84 279.9 1.2 3.4 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBY15208.1 - 4.4e-66 221.9 8.3 1.1e-62 210.7 0.5 4.3 4 1 1 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBY15208.1 - 7.8e-55 185.1 0.0 2e-54 183.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBY15208.1 - 9.7e-44 148.3 0.0 2.5e-42 143.7 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBY15208.1 - 2.9e-40 138.4 6.4 4.9e-40 137.6 6.4 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBY15208.1 - 1.4e-25 89.9 0.1 4.4e-08 33.2 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CBY15208.1 - 7.7e-19 67.8 0.0 4.9e-18 65.2 0.0 2.4 2 0 0 2 2 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CBY15208.1 - 2.9e-18 66.2 0.6 1.8e-17 63.6 0.3 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CBY15208.1 - 1.2e-08 35.4 0.6 0.27 11.7 0.0 4.6 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY15208.1 - 3.4e-05 24.1 0.5 3.3 8.0 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 CBY15208.1 - 8e-05 23.1 0.4 1.8 8.9 0.0 4.8 4 0 0 4 4 4 1 AAA ATPase domain BRE1 PF08647.11 CBY15208.1 - 0.001 19.1 0.7 0.001 19.1 0.7 3.2 3 0 0 3 3 1 1 BRE1 E3 ubiquitin ligase AAA_18 PF13238.6 CBY15208.1 - 0.0032 18.0 1.0 19 5.8 0.0 4.5 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 CBY15208.1 - 0.016 15.1 0.4 0.76 9.7 0.0 3.5 3 1 0 3 3 3 0 Rad17 P-loop domain Sigma54_activat PF00158.26 CBY15208.1 - 0.033 13.9 0.1 26 4.5 0.0 3.6 3 0 0 3 3 3 0 Sigma-54 interaction domain Roc PF08477.13 CBY15208.1 - 0.033 14.4 1.4 7.8 6.7 0.1 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 CBY15208.1 - 0.04 14.3 0.4 3.1 8.2 0.0 3.5 3 0 0 3 3 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 CBY15208.1 - 0.055 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 CBY15208.1 - 0.059 13.7 5.3 5 7.4 0.1 3.9 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CBY15208.1 - 0.065 13.0 1.9 2.7 7.8 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CBY15208.1 - 0.07 13.6 0.7 2.4 8.7 0.0 3.5 3 0 0 3 3 3 0 ABC transporter AAA_33 PF13671.6 CBY15208.1 - 0.077 13.2 2.1 1.3 9.1 0.0 3.7 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.6 CBY15208.1 - 0.085 12.6 0.5 8.7 6.0 0.1 2.9 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CBY15208.1 - 0.31 9.9 1.7 0.84 8.5 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1_C PF08438.10 CBY15208.1 - 0.4 11.3 1.9 1.9 9.1 1.9 2.2 1 0 0 1 1 1 0 GTPase of unknown function C-terminal TsaE PF02367.17 CBY15208.1 - 0.87 9.6 9.4 9.6 6.2 0.0 4.1 5 0 0 5 5 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 CBY15208.1 - 1.6 8.4 7.6 3.3 7.4 0.2 4.1 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.8 CBY15208.1 - 6.1 4.2 13.6 0.7 7.3 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) EGF_CA PF07645.15 CBY15209.1 - 2.8e-56 187.5 95.2 3.8e-11 43.0 7.5 7.6 7 0 0 7 7 7 6 Calcium-binding EGF domain cEGF PF12662.7 CBY15209.1 - 3.2e-11 42.9 53.2 0.00048 20.0 4.6 7.3 7 0 0 7 7 7 5 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY15209.1 - 8.9e-11 41.8 84.3 0.0009 19.4 10.4 7.1 6 0 0 6 6 6 6 EGF domain FXa_inhibition PF14670.6 CBY15209.1 - 4.5e-05 23.6 78.9 0.096 13.0 9.0 7.0 6 1 1 7 7 7 5 Coagulation Factor Xa inhibitory site Nucleos_tra2_N PF01773.20 CBY15210.1 - 6.8e-20 71.5 4.6 6.8e-20 71.5 4.6 3.9 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CBY15210.1 - 0.00018 21.8 6.8 0.00018 21.8 6.8 2.4 3 1 0 3 3 3 1 Nucleoside recognition Nucleos_tra2_C PF07662.13 CBY15210.1 - 0.00035 20.5 0.3 0.00035 20.5 0.3 2.2 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus PsbN PF02468.15 CBY15210.1 - 5.7 6.9 8.1 1.4 8.9 0.8 3.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) O-FucT PF10250.9 CBY15212.1 - 0.0081 15.9 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF4158 PF13700.6 CBY15213.1 - 0.053 13.4 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Sulfotransfer_2 PF03567.14 CBY15214.1 - 2.5e-12 47.3 0.1 3.4e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family EGF_CA PF07645.15 CBY15215.1 - 4.4e-119 388.5 323.3 1.6e-10 41.0 8.0 24.7 21 3 3 24 24 24 20 Calcium-binding EGF domain EGF_3 PF12947.7 CBY15215.1 - 9.2e-75 246.5 277.2 2e-08 34.3 6.7 24.2 21 3 3 24 24 24 21 EGF domain cEGF PF12662.7 CBY15215.1 - 3.6e-45 151.5 215.7 4.5e-06 26.5 3.9 22.9 22 0 0 22 22 22 17 Complement Clr-like EGF-like EGF PF00008.27 CBY15215.1 - 1.1e-31 108.8 272.9 0.0001 22.5 4.5 24.0 23 0 0 23 23 23 19 EGF-like domain FXa_inhibition PF14670.6 CBY15215.1 - 9.3e-17 61.0 283.3 0.0019 18.4 5.0 23.5 18 4 5 23 23 23 15 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY15215.1 - 2.4e-10 40.7 240.6 0.00021 21.8 2.0 23.5 22 0 0 22 22 22 14 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY15215.1 - 0.00059 19.8 2.4 0.00059 19.8 2.4 21.5 21 0 0 21 21 21 10 MSP1 EGF domain 1 p450 PF00067.22 CBY15217.1 - 9.2e-61 206.0 0.0 1.2e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BBS2_C PF14782.6 CBY15218.1 - 7.3e-27 94.2 3.0 9.4e-27 93.8 3.0 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal KH_8 PF17903.1 CBY15218.1 - 1.3e-07 31.6 0.9 2.7e-07 30.6 0.1 1.9 2 1 0 2 2 2 1 Krr1 KH1 domain DUF4363 PF14276.6 CBY15218.1 - 0.0013 18.8 2.9 0.056 13.6 0.9 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4363) ATP-gua_PtransN PF02807.15 CBY15219.1 - 4.4e-10 39.8 0.1 7.3e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF4329 PF14220.6 CBY15219.1 - 0.0022 18.0 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) ATP-gua_Ptrans PF00217.19 CBY15220.1 - 1.4e-36 126.0 0.0 7.4e-26 90.9 0.0 2.0 1 1 1 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain MGAT2 PF05060.14 CBY15221.1 - 5.9e-25 88.1 0.4 8.5e-25 87.5 0.4 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) MGAT2 PF05060.14 CBY15222.1 - 2.4e-12 46.6 0.0 2.5e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) ARID PF01388.21 CBY15223.1 - 0.079 13.6 0.0 0.15 12.8 0.0 1.6 1 1 0 1 1 1 0 ARID/BRIGHT DNA binding domain DUF4994 PF16385.5 CBY15227.1 - 0.088 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Ank_2 PF12796.7 CBY15228.1 - 4.6e-47 158.5 5.5 1.2e-16 61.1 0.1 5.7 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY15228.1 - 6.5e-34 112.1 2.1 1.1e-06 28.5 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 CBY15228.1 - 1.8e-33 114.1 4.2 3e-07 30.6 0.0 6.2 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY15228.1 - 2.7e-33 113.9 3.1 3e-11 43.6 0.1 7.4 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 CBY15228.1 - 1.2e-31 107.7 0.9 2.2e-06 27.9 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat SAM_2 PF07647.17 CBY15228.1 - 7.5e-12 45.2 1.1 1.3e-10 41.2 0.2 3.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY15228.1 - 6.6e-10 39.3 0.6 1.7e-09 38.0 0.3 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Tau95_N PF17682.1 CBY15228.1 - 0.0091 16.2 1.1 0.034 14.3 1.1 2.1 1 1 0 1 1 1 1 Tau95 Triple barrel domain Amidinotransf PF02274.17 CBY15229.1 - 2.9e-10 39.8 0.1 2e-08 33.7 0.1 2.1 1 1 0 1 1 1 1 Amidinotransferase Homeobox_KN PF05920.11 CBY15230.1 - 6.7e-15 54.7 0.1 1.3e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY15230.1 - 2.6e-06 27.2 0.2 4.4e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Exo_endo_phos PF03372.23 CBY15231.1 - 1.6e-09 37.7 0.1 2.6e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phytase-like PF13449.6 CBY15231.1 - 0.038 13.9 0.2 8.1 6.3 0.2 2.9 2 1 1 3 3 3 0 Esterase-like activity of phytase Exo_endo_phos_2 PF14529.6 CBY15231.1 - 0.14 12.0 1.3 0.4 10.5 0.1 2.5 4 0 0 4 4 4 0 Endonuclease-reverse transcriptase Mt_ATP_synt PF15704.5 CBY15232.1 - 0.2 11.5 5.8 0.29 11.0 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit Aldolase_II PF00596.21 CBY15233.1 - 1.3e-44 152.4 0.0 1.5e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sulfotransfer_1 PF00685.27 CBY15234.1 - 2.7e-18 66.4 0.0 5e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain EGF_3 PF12947.7 CBY15234.1 - 2e-07 31.1 24.2 6.3e-05 23.1 7.8 2.7 2 0 0 2 2 2 2 EGF domain Sulfotransfer_3 PF13469.6 CBY15234.1 - 1.7e-06 28.6 0.0 0.62 10.4 0.0 3.4 2 1 1 3 3 3 3 Sulfotransferase family EGF_2 PF07974.13 CBY15234.1 - 0.0005 20.4 14.2 0.0065 16.8 5.9 2.8 1 1 1 2 2 2 2 EGF-like domain EGF PF00008.27 CBY15234.1 - 0.45 10.9 20.4 0.49 10.8 9.6 2.9 2 0 0 2 2 2 0 EGF-like domain EGF_CA PF07645.15 CBY15234.1 - 1.6 9.0 20.4 0.29 11.4 5.6 2.7 1 1 0 2 2 2 0 Calcium-binding EGF domain cEGF PF12662.7 CBY15234.1 - 3 7.9 8.0 8.1 6.5 2.8 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like BON PF04972.17 CBY15235.1 - 0.03 14.6 0.1 0.05 13.9 0.1 1.3 1 0 0 1 1 1 0 BON domain Phospholip_A2_1 PF00068.19 CBY15236.1 - 4.3e-10 40.0 3.4 4.3e-10 40.0 3.4 1.6 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY15238.1 - 1.4e-13 51.3 3.1 1.4e-13 51.3 3.1 2.3 2 0 0 2 2 2 1 Phospholipase A2 EGF_CA PF07645.15 CBY15239.1 - 2.1e-05 24.6 9.4 2.1e-05 24.6 9.4 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain Holin_BhlA PF10960.8 CBY15241.1 - 0.0073 16.2 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 BhlA holin family UPF0542 PF15086.6 CBY15241.1 - 0.055 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 7TMR-DISM_7TM PF07695.11 CBY15241.1 - 0.18 11.7 9.5 0.21 11.4 9.5 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF2207 PF09972.9 CBY15241.1 - 0.38 9.5 3.2 0.51 9.0 3.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1053 PF06327.14 CBY15242.1 - 0.074 13.6 1.4 0.26 11.8 0.3 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) RhoGAP PF00620.27 CBY15244.1 - 2.2e-38 131.5 0.0 4.6e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain START PF01852.19 CBY15244.1 - 5.2e-19 68.5 0.2 9e-19 67.7 0.2 1.3 1 0 0 1 1 1 1 START domain Rx_N PF18052.1 CBY15244.1 - 0.17 12.2 2.1 2.3 8.5 0.4 2.6 2 0 0 2 2 2 0 Rx N-terminal domain Cytochrome_CBB3 PF13442.6 CBY15245.1 - 0.31 11.4 1.5 31 5.0 1.1 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Dicty_REP PF05086.12 CBY15245.1 - 2.4 6.0 9.8 2.8 5.8 9.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cytochrom_CIII PF02085.16 CBY15245.1 - 2.9 8.3 10.5 2 8.8 3.6 2.4 2 1 0 2 2 2 0 Class III cytochrome C family FSA_C PF10479.9 CBY15245.1 - 7.7 4.5 10.8 10 4.1 10.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FOXP-CC PF16159.5 CBY15246.1 - 0.0035 17.9 0.1 0.0075 16.9 0.1 1.5 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 CBY15246.1 - 0.047 14.1 0.2 0.11 13.1 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY15246.1 - 0.063 14.1 0.2 0.15 13.0 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Zip PF02535.22 CBY15247.1 - 0.0093 15.2 0.8 0.011 15.0 0.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Presenilin PF01080.17 CBY15247.1 - 0.014 14.2 7.7 0.016 14.0 7.7 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CBY15247.1 - 0.017 15.2 0.8 0.019 15.0 0.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endomucin PF07010.12 CBY15247.1 - 0.053 13.5 21.8 0.059 13.3 21.8 1.1 1 0 0 1 1 1 0 Endomucin Raftlin PF15250.6 CBY15247.1 - 0.094 11.5 7.1 0.11 11.3 7.1 1.0 1 0 0 1 1 1 0 Raftlin ABC2_membrane_3 PF12698.7 CBY15247.1 - 0.13 11.3 8.4 0.17 11.0 8.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MDFI PF15316.6 CBY15247.1 - 0.15 12.2 6.8 0.19 11.8 6.8 1.1 1 0 0 1 1 1 0 MyoD family inhibitor MCLC PF05934.11 CBY15247.1 - 0.39 9.4 13.0 0.48 9.1 13.0 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) RIFIN PF02009.16 CBY15247.1 - 0.6 9.9 9.5 0.67 9.8 9.5 1.2 1 0 0 1 1 1 0 Rifin Suf PF05843.14 CBY15247.1 - 0.61 10.0 10.2 0.67 9.9 10.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CBY15247.1 - 0.79 9.7 17.0 0.93 9.4 17.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pannexin_like PF12534.8 CBY15247.1 - 1.4 7.9 10.9 1.8 7.6 10.9 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Ndc1_Nup PF09531.10 CBY15247.1 - 1.4 7.5 12.4 1.7 7.2 12.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.13 CBY15247.1 - 1.5 7.8 13.3 1.9 7.4 13.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4400 PF14348.6 CBY15247.1 - 2.9 7.4 6.5 4 6.9 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Plasmodium_Vir PF05795.11 CBY15247.1 - 3.3 7.0 7.4 4.5 6.6 7.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF572 PF04502.13 CBY15247.1 - 3.6 7.1 14.0 4.3 6.9 14.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.9 CBY15247.1 - 7.4 5.7 20.6 8.5 5.5 20.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.17 CBY15247.1 - 7.6 6.5 40.1 1.6e+02 2.2 40.1 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein Zip PF02535.22 CBY15248.1 - 0.0077 15.5 0.3 0.0085 15.4 0.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MDFI PF15316.6 CBY15248.1 - 0.011 15.8 3.8 0.014 15.5 3.8 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Raftlin PF15250.6 CBY15248.1 - 0.026 13.3 5.0 0.029 13.1 5.0 1.0 1 0 0 1 1 1 0 Raftlin Suf PF05843.14 CBY15248.1 - 0.051 13.6 6.5 0.056 13.4 6.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ABC2_membrane_3 PF12698.7 CBY15248.1 - 0.054 12.6 6.9 0.068 12.3 6.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MCLC PF05934.11 CBY15248.1 - 0.6 8.8 13.0 0.75 8.4 13.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) TFIIA PF03153.13 CBY15248.1 - 0.73 9.8 16.3 0.87 9.5 16.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CBY15248.1 - 0.87 8.6 11.9 1.1 8.2 11.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pannexin_like PF12534.8 CBY15248.1 - 1.7 7.7 10.7 2.5 7.1 10.7 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF4400 PF14348.6 CBY15248.1 - 1.8 8.0 5.2 2.5 7.6 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) RIFIN PF02009.16 CBY15248.1 - 2.1 8.2 10.1 2.5 7.9 10.1 1.1 1 0 0 1 1 1 0 Rifin DUF5521 PF17659.1 CBY15248.1 - 2.7 5.8 10.7 2.9 5.6 10.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) GET2 PF08690.10 CBY15248.1 - 3 7.4 11.9 3.9 7.1 11.9 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 FAM60A PF15396.6 CBY15248.1 - 6.4 6.7 6.8 8.8 6.3 6.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF572 PF04502.13 CBY15248.1 - 7.5 6.1 14.4 9.4 5.7 14.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 CBY15248.1 - 8.1 3.4 13.6 9.4 3.2 13.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Phospholip_A2_1 PF00068.19 CBY15250.1 - 0.00013 22.4 0.0 0.00033 21.1 0.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 Galactosyl_T PF01762.21 CBY15251.1 - 4.3e-17 62.6 0.1 1.4e-16 60.9 0.1 1.7 1 1 0 1 1 1 1 Galactosyltransferase DUF4603 PF15376.6 CBY15252.1 - 0.046 11.1 16.2 0.052 11.0 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FAM60A PF15396.6 CBY15252.1 - 0.34 10.9 19.9 0.52 10.3 19.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A NPAT_C PF15712.5 CBY15252.1 - 1.5 7.4 25.8 1.8 7.1 25.8 1.1 1 0 0 1 1 1 0 NPAT C terminus CRT10 PF08728.10 CBY15252.1 - 2.2 6.3 14.2 2.6 6.1 14.2 1.1 1 0 0 1 1 1 0 CRT10 RR_TM4-6 PF06459.12 CBY15252.1 - 2.6 7.8 27.5 4.2 7.1 27.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dsh_C PF12316.8 CBY15252.1 - 3.2 8.1 8.9 4.7 7.6 8.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal GREB1 PF15782.5 CBY15252.1 - 4.2 4.3 13.0 4.5 4.3 13.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MMU163 PF17119.5 CBY15252.1 - 4.7 6.3 12.1 7.2 5.7 12.1 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis SLC12 PF03522.15 CBY15252.1 - 5.2 6.0 21.0 6.8 5.6 21.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2370 PF10176.9 CBY15252.1 - 5.4 6.6 6.5 8.1 6.0 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Presenilin PF01080.17 CBY15252.1 - 6.5 5.4 22.9 8.7 5.0 22.9 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CBY15252.1 - 7.1 4.6 21.1 9.3 4.2 21.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CBY15252.1 - 7.1 5.3 22.6 11 4.7 22.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ALMT PF11744.8 CBY15252.1 - 8.2 5.1 16.1 10 4.8 16.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 CBY15252.1 - 8.7 5.1 11.9 11 4.8 11.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PA26 PF04636.13 CBY15252.1 - 8.8 5.1 14.7 12 4.7 14.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Lactamase_B_6 PF16661.5 CBY15253.1 - 0.0094 15.4 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain ARID PF01388.21 CBY15254.1 - 1.9e-17 63.7 0.0 3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CybS PF05328.12 CBY15254.1 - 0.089 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit Uteroglobin PF01099.17 CBY15254.1 - 0.13 12.6 0.2 0.65 10.4 0.0 2.0 2 0 0 2 2 2 0 Uteroglobin family eRF1_1 PF03463.15 CBY15254.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 eRF1 domain 1 Pkinase PF00069.25 CBY15255.1 - 4.4e-16 59.0 0.3 1.4e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15255.1 - 2.6e-08 33.5 0.0 6.9e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase MIF4G PF02854.19 CBY15255.1 - 0.00018 21.2 1.1 0.00018 21.2 1.1 3.0 3 1 0 3 3 3 1 MIF4G domain DUF241 PF03087.14 CBY15255.1 - 0.046 13.6 8.4 0.11 12.3 8.4 1.7 1 0 0 1 1 1 0 Arabidopsis protein of unknown function PHM7_cyt PF14703.6 CBY15255.1 - 0.046 14.0 2.6 0.13 12.5 2.6 1.8 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Viral_P18 PF04521.13 CBY15255.1 - 0.13 12.0 0.8 18 5.1 0.4 2.7 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein CpxA_peri PF16527.5 CBY15255.1 - 4.5 7.7 8.6 13 6.2 0.1 2.9 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain Zip PF02535.22 CBY15256.1 - 3.6e-17 62.6 10.1 1.3e-16 60.8 10.1 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Capsid_VP7 PF17071.5 CBY15256.1 - 0.008 15.5 0.2 0.013 14.9 0.2 1.2 1 0 0 1 1 1 1 Outer capsid protein VP7 DUF2530 PF10745.9 CBY15256.1 - 8.5 6.7 8.0 15 5.9 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Phospholip_A2_1 PF00068.19 CBY15257.1 - 2.4e-17 63.4 9.6 2.4e-17 63.4 9.6 1.7 2 0 0 2 2 2 1 Phospholipase A2 TINF2_N PF14973.6 CBY15259.1 - 0.3 11.4 9.4 0.37 11.1 2.4 2.6 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF3450 PF11932.8 CBY15259.1 - 1.3 8.3 25.9 0.063 12.6 3.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 CBY15259.1 - 5.9 7.4 6.7 15 6.1 1.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MARVEL PF01284.23 CBY15260.1 - 0.0097 15.9 5.6 0.015 15.3 5.3 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF5337 PF17272.2 CBY15260.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5337) Ribosomal_L10 PF00466.20 CBY15263.1 - 2.2e-22 79.1 2.0 6.7e-22 77.5 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 CBY15263.1 - 7.8e-17 61.0 0.2 3.3e-16 59.1 0.1 2.1 3 0 0 3 3 3 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CBY15263.1 - 1.5e-14 54.4 13.0 2.9e-14 53.4 11.0 2.4 3 0 0 3 3 3 1 60s Acidic ribosomal protein Ribonuc_L-PSP PF01042.21 CBY15263.1 - 0.015 15.3 0.2 0.033 14.2 0.2 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP p450 PF00067.22 CBY15264.1 - 6.8e-82 275.7 1.7 9.5e-82 275.2 1.7 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sigma70_r1_2 PF00140.20 CBY15264.1 - 0.077 13.0 0.0 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 PhoU PF01895.19 CBY15264.1 - 2.3 8.8 5.4 47 4.5 0.1 3.3 3 0 0 3 3 3 0 PhoU domain Far-17a_AIG1 PF04750.14 CBY15265.1 - 2.4e-15 56.4 11.1 3.2e-15 56.0 11.1 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pkinase PF00069.25 CBY15266.1 - 2.7e-10 40.1 0.5 5.1e-10 39.1 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15266.1 - 3.5e-09 36.3 0.0 6.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2070 PF09843.9 CBY15268.1 - 0.15 10.4 0.0 0.23 9.7 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RCS1 PF07326.11 CBY15269.1 - 0.0084 16.1 3.0 0.0084 16.1 3.0 1.9 2 0 0 2 2 2 1 Regulator of chromosome segregation 1 GMP_synt_C PF00958.22 CBY15270.1 - 2.5e-11 43.5 0.0 6.1e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 GMP synthase C terminal domain Lipid_DES PF08557.10 CBY15270.1 - 0.08 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Kelch_2 PF07646.15 CBY15271.1 - 0.00046 20.1 0.6 0.17 11.9 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY15271.1 - 0.00099 19.3 2.1 0.44 10.9 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CBY15271.1 - 0.01 15.8 6.1 0.014 15.4 0.0 3.4 3 0 0 3 3 3 0 Kelch motif zf-C3HC4_3 PF13920.6 CBY15273.1 - 1.1e-06 28.4 4.1 1.1e-06 28.4 4.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY15273.1 - 5.8e-05 23.0 7.5 5.8e-05 23.0 7.5 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY15273.1 - 6.3e-05 23.2 8.8 0.00017 21.9 7.4 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBY15273.1 - 0.00013 21.7 5.4 0.00013 21.7 5.4 2.0 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY15273.1 - 0.0025 17.6 7.2 0.003 17.4 5.0 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY15273.1 - 0.0046 16.7 8.2 0.0097 15.7 6.8 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF745 PF05335.13 CBY15273.1 - 0.0078 16.0 6.8 0.01 15.6 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) zf-RING_11 PF17123.5 CBY15273.1 - 0.024 14.4 1.6 0.024 14.4 1.6 2.3 3 0 0 3 3 3 0 RING-like zinc finger DUF2256 PF10013.9 CBY15273.1 - 0.024 14.7 0.1 0.024 14.7 0.1 3.4 4 0 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2256) YscO-like PF16789.5 CBY15273.1 - 0.05 13.6 12.9 0.059 13.4 12.9 1.2 1 0 0 1 1 1 0 YscO-like protein Rad50_zn_hook PF04423.14 CBY15273.1 - 0.054 13.3 0.1 0.054 13.3 0.1 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif FAM25 PF15825.5 CBY15273.1 - 0.063 13.6 3.0 0.12 12.7 3.0 1.5 1 0 0 1 1 1 0 FAM25 family zf-C3HC4_2 PF13923.6 CBY15273.1 - 0.077 12.9 10.4 0.32 10.9 9.6 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) QIL1 PF15884.5 CBY15273.1 - 0.11 13.1 0.2 4 8.1 0.1 2.3 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 zf-RING_UBOX PF13445.6 CBY15273.1 - 0.15 12.1 8.1 0.13 12.3 2.1 2.9 3 0 0 3 3 3 0 RING-type zinc-finger ADIP PF11559.8 CBY15273.1 - 0.19 11.8 8.7 0.25 11.4 8.1 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 CBY15273.1 - 0.6 8.6 5.7 0.72 8.4 5.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A ETRAMP PF09716.10 CBY15273.1 - 0.64 10.1 3.0 0.92 9.6 3.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Spc7 PF08317.11 CBY15273.1 - 1.4 7.7 13.2 1.7 7.4 13.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TRAP_alpha PF03896.16 CBY15273.1 - 1.7 7.8 6.8 1.9 7.6 6.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.10 CBY15273.1 - 2 8.5 8.0 2.2 8.3 8.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Prok-RING_1 PF14446.6 CBY15273.1 - 3.8 7.5 10.7 5.1 7.1 0.1 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 Rtf2 PF04641.12 CBY15273.1 - 5.7 6.2 20.1 0.65 9.3 2.8 2.2 1 1 1 2 2 2 0 Rtf2 RING-finger GMC_oxred_C PF05199.13 CBY15274.1 - 1.5e-39 135.8 0.1 2.2e-39 135.3 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase zf-CCCH PF00642.24 CBY15278.1 - 0.00081 19.2 2.3 0.0018 18.1 2.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY15278.1 - 0.00082 19.3 2.0 0.00082 19.3 2.0 2.4 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 CBY15278.1 - 0.0014 19.3 0.2 0.013 16.2 0.1 2.5 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 CBY15278.1 - 0.058 13.2 2.0 0.12 12.2 2.0 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger Vps52 PF04129.12 CBY15279.1 - 0.052 12.3 0.9 0.065 12.0 0.9 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family PfkB PF00294.24 CBY15280.1 - 4.5e-24 85.3 0.0 6.2e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Nop14 PF04147.12 CBY15281.1 - 0.0087 14.3 3.4 0.0082 14.4 3.4 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4637 PF15470.6 CBY15281.1 - 0.018 14.7 4.6 0.026 14.2 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Fucose_iso_N2 PF07882.12 CBY15281.1 - 0.12 11.9 2.3 0.14 11.7 2.3 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Bombesin PF02044.17 CBY15281.1 - 0.17 12.0 1.1 0.36 11.0 1.1 1.5 1 0 0 1 1 1 0 Bombesin-like peptide CENP-B_dimeris PF09026.10 CBY15281.1 - 0.48 10.8 11.5 0.8 10.1 11.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 CBY15281.1 - 0.51 10.7 4.1 1.2 9.6 4.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 CBY15281.1 - 0.61 9.7 7.0 1.1 8.9 7.0 1.3 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 CBY15281.1 - 1.2 7.2 13.7 1.5 6.8 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4820 PF16091.5 CBY15281.1 - 1.3 8.3 4.5 2 7.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDC45 PF02724.14 CBY15281.1 - 2.4 6.3 7.0 3 6.0 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 CBY15281.1 - 5.5 6.0 15.3 7.4 5.6 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AsnA PF03590.15 CBY15284.1 - 0.00053 19.8 0.5 0.00072 19.4 0.5 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase MFS_1 PF07690.16 CBY15284.1 - 0.00055 19.0 0.0 0.00076 18.5 0.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CBY15284.1 - 0.1 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein VWA PF00092.28 CBY15285.1 - 4.9e-13 49.7 0.0 1e-12 48.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 CBY15285.1 - 8.9e-10 38.6 26.7 1.7e-06 28.1 7.4 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain FXa_inhibition PF14670.6 CBY15285.1 - 0.011 16.0 9.1 0.011 16.0 9.1 3.1 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site DPPIV_N PF00930.21 CBY15286.1 - 3.5e-29 101.7 1.0 4e-29 101.5 0.3 1.4 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 CBY15286.1 - 0.0024 17.8 0.1 0.0024 17.8 0.1 3.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat PHtD_u1 PF16645.5 CBY15286.1 - 0.28 11.6 2.3 1.2 9.7 2.3 2.0 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein ArsR PF09824.9 CBY15287.1 - 0.035 13.7 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 ArsR transcriptional regulator Pput2613-deam PF14427.6 CBY15287.1 - 0.043 13.7 0.1 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Pput_2613-like deaminase Glyco_transf_7C PF02709.14 CBY15288.1 - 1.7e-24 85.3 0.7 2.9e-24 84.5 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CBY15288.1 - 3.3e-22 78.6 0.5 6.3e-22 77.7 0.5 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 OAD_gamma PF04277.13 CBY15288.1 - 0.093 13.3 0.5 0.17 12.5 0.5 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Trypsin PF00089.26 CBY15289.1 - 1.8e-49 168.6 0.4 3e-49 167.8 0.4 1.4 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 CBY15289.1 - 1.5e-31 108.9 0.1 9.3e-14 51.7 0.0 3.7 3 0 0 3 3 3 3 CUB domain Lectin_C PF00059.21 CBY15289.1 - 1.1e-11 45.4 0.9 3.3e-11 43.9 0.1 2.4 2 0 0 2 2 2 1 Lectin C-type domain CUB_2 PF02408.20 CBY15289.1 - 6.8e-07 29.1 0.9 0.043 13.6 0.0 3.5 3 1 0 3 3 3 2 CUB-like domain Trypsin_2 PF13365.6 CBY15289.1 - 1.5e-05 26.0 0.0 4.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kelch_5 PF13854.6 CBY15290.1 - 0.023 14.7 0.0 0.023 14.7 0.0 2.5 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY15290.1 - 0.38 10.8 2.1 0.52 10.4 0.1 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain Lectin_C PF00059.21 CBY15291.1 - 8.9e-16 58.6 15.5 2.5e-10 41.0 0.2 2.7 3 0 0 3 3 3 2 Lectin C-type domain Trefoil PF00088.18 CBY15291.1 - 0.014 15.2 5.0 0.071 13.0 5.0 2.3 1 0 0 1 1 1 0 Trefoil (P-type) domain Glyco_hydro_77 PF02446.17 CBY15291.1 - 0.032 13.1 0.1 0.04 12.8 0.1 1.2 1 0 0 1 1 1 0 4-alpha-glucanotransferase RIIa PF02197.17 CBY15292.1 - 0.075 12.7 1.8 0.096 12.4 0.3 2.0 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit DUF359 PF04019.12 CBY15292.1 - 0.67 9.6 2.5 0.93 9.1 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF359) Kelch_2 PF07646.15 CBY15293.1 - 7e-05 22.6 2.2 0.74 9.9 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY15293.1 - 0.0049 17.1 0.7 0.96 9.8 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CBY15293.1 - 0.009 16.0 0.1 0.009 16.0 0.1 3.4 4 0 0 4 4 4 1 Kelch motif COX6B PF02297.17 CBY15295.1 - 7.9e-11 42.0 1.1 1.4e-10 41.3 1.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pkinase_Tyr PF07714.17 CBY15296.1 - 6.4e-15 55.1 0.0 7.6e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY15296.1 - 1.6e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain COG2 PF06148.11 CBY15298.1 - 4.1e-32 111.0 1.5 4.1e-32 111.0 1.5 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 CBY15298.1 - 1.2e-28 100.1 0.4 1.2e-28 100.1 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 CBY15298.1 - 0.005 16.9 6.8 0.055 13.5 0.1 4.2 4 0 0 4 4 4 1 Vps51/Vps67 RNase_J_C PF17770.1 CBY15298.1 - 0.044 14.8 2.3 0.66 11.1 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain DUF3258 PF11646.8 CBY15298.1 - 0.057 13.5 0.5 17 5.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF3258 DUF2120 PF09893.9 CBY15298.1 - 0.063 13.4 0.6 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Phage_Arf PF17585.2 CBY15298.1 - 0.074 13.0 0.7 0.19 11.7 0.7 1.7 1 0 0 1 1 1 0 Accessory recombination function protein PEX11 PF05648.14 CBY15298.1 - 0.11 12.0 1.0 0.61 9.5 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) MMR_HSR1 PF01926.23 CBY15299.1 - 5.8e-17 61.8 4.3 7.6e-15 55.0 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY15299.1 - 1.5e-11 44.0 0.0 2.9e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GN3L_Grn1 PF08701.11 CBY15299.1 - 2.4e-11 43.6 19.9 2.4e-11 43.6 19.9 3.0 3 0 0 3 3 3 1 GNL3L/Grn1 putative GTPase RsgA_GTPase PF03193.16 CBY15299.1 - 4.3e-06 26.7 0.3 0.011 15.6 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY15299.1 - 6.6e-05 22.5 0.0 0.00043 19.9 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBY15299.1 - 0.00072 19.6 6.9 0.4 10.7 0.2 4.6 2 2 1 3 3 3 1 Dynamin family Roc PF08477.13 CBY15299.1 - 0.03 14.5 0.4 1.6 8.9 0.0 2.9 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CBY15299.1 - 0.51 10.7 2.8 0.4 11.1 0.1 2.2 2 2 0 2 2 2 0 AAA ATPase domain DUF2939 PF11159.8 CBY15300.1 - 0.42 11.1 1.7 9.9 6.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) zf-C2H2 PF00096.26 CBY15302.1 - 1.8e-21 75.3 65.4 8.2e-06 26.0 3.6 8.8 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY15302.1 - 2.1e-18 65.4 56.7 0.00014 22.4 1.3 8.9 9 0 0 9 9 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY15302.1 - 2.9e-12 46.4 63.9 0.00037 20.8 0.3 9.3 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY15302.1 - 7e-11 41.9 36.5 2.3e-06 27.4 0.8 7.5 7 1 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 CBY15302.1 - 9.6e-10 38.5 20.5 0.015 15.7 1.0 6.1 6 1 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CBY15302.1 - 1.1e-05 25.0 4.7 0.00022 20.9 0.6 4.9 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CBY15302.1 - 0.00052 20.2 39.6 0.00065 19.9 2.1 7.4 7 1 1 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY15302.1 - 0.028 14.8 44.0 0.5 10.7 6.1 7.0 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 CBY15302.1 - 0.44 11.3 20.4 0.49 11.2 2.3 4.1 3 1 1 4 4 4 0 zinc-ribbon family BolA PF01722.18 CBY15302.1 - 0.6 10.4 6.7 24 5.3 0.5 3.7 3 1 1 4 4 4 0 BolA-like protein zf-FPG_IleRS PF06827.14 CBY15302.1 - 1.7 8.6 6.4 32 4.5 0.0 4.1 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS DUF5025 PF16428.5 CBY15303.1 - 0.067 13.4 0.0 0.1 12.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5025) Hydrolase_4 PF12146.8 CBY15304.1 - 1.1e-12 47.7 0.0 4.9e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY15304.1 - 6e-11 42.5 0.0 0.00015 21.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY15304.1 - 1.9e-06 28.6 0.0 3.1e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 CBY15304.1 - 6.1e-05 22.8 0.0 7.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 CBY15304.1 - 7.8e-05 22.7 0.0 0.0075 16.2 0.0 2.1 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 CBY15304.1 - 0.001 18.1 0.0 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 CBY15304.1 - 0.0017 17.9 0.0 0.0066 15.9 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CBY15304.1 - 0.0046 16.6 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 CBY15304.1 - 0.031 13.8 0.0 0.15 11.6 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 CBY15304.1 - 0.19 11.5 0.0 1.9 8.3 0.0 2.0 1 1 0 2 2 2 0 Alpha/beta hydrolase family DUF1057 PF06342.12 CBY15304.1 - 0.22 10.5 0.0 1.3 8.0 0.0 1.8 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Solute_trans_a PF03619.16 CBY15305.1 - 2.5e-40 138.7 7.3 3.4e-40 138.2 7.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.16 CBY15306.1 - 2e-10 40.7 0.1 2.5e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Integrase_H2C2 PF17921.1 CBY15309.1 - 0.00015 21.8 0.1 0.00052 20.1 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain CENP-K PF11802.8 CBY15309.1 - 0.002 17.8 1.3 0.004 16.8 1.3 1.4 1 0 0 1 1 1 1 Centromere-associated protein K YicC_N PF03755.13 CBY15309.1 - 0.049 14.1 0.1 0.14 12.6 0.1 1.8 2 0 0 2 2 2 0 YicC-like family, N-terminal region 7tm_1 PF00001.21 CBY15310.1 - 0.21 10.9 6.3 0.066 12.5 2.7 1.8 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Zona_pellucida PF00100.23 CBY15311.1 - 1.5e-17 64.3 3.2 1.8e-17 64.0 3.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain fn3_6 PF17766.1 CBY15311.1 - 0.13 12.5 0.6 0.23 11.6 0.6 1.5 1 0 0 1 1 1 0 Fibronectin type-III domain AdoHcyase PF05221.17 CBY15312.1 - 5.4e-119 396.8 0.0 5.2e-65 219.5 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CBY15312.1 - 1.3e-77 259.4 3.1 2.3e-77 258.6 3.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CBY15312.1 - 1.8e-09 37.2 0.2 3.5e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBY15312.1 - 1.2e-06 28.2 0.1 2e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 CBY15312.1 - 0.00015 21.1 2.8 0.00055 19.3 2.8 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.21 CBY15312.1 - 0.00048 19.5 2.3 0.0015 17.9 2.3 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CBY15312.1 - 0.0016 18.8 0.6 0.011 16.2 0.3 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.18 CBY15312.1 - 0.028 14.7 0.7 0.11 12.7 0.7 2.1 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 CBY15312.1 - 0.032 14.3 0.1 0.076 13.1 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 CBY15312.1 - 0.069 12.9 1.3 0.96 9.1 1.4 2.1 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MDH PF02315.16 CBY15313.1 - 0.08 13.0 0.7 0.15 12.1 0.7 1.5 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit IF4E PF01652.18 CBY15314.1 - 6.8e-41 139.7 0.5 1e-40 139.2 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E A1_Propeptide PF07966.12 CBY15314.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 A1 Propeptide MFS_Mycoplasma PF07672.13 CBY15315.1 - 0.012 15.0 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter Chromo PF00385.24 CBY15318.1 - 9.7e-13 47.8 5.3 9.7e-13 47.8 5.3 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Herpes_DNAp_acc PF04929.12 CBY15318.1 - 0.029 13.4 1.6 0.037 13.0 1.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DSS1_SEM1 PF05160.13 CBY15318.1 - 0.059 13.4 4.7 0.18 11.9 4.7 1.8 1 0 0 1 1 1 0 DSS1/SEM1 family CDC45 PF02724.14 CBY15318.1 - 1 7.6 5.7 1.1 7.4 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein TBCA PF02970.16 CBY15319.1 - 1.6e-17 63.6 4.6 2e-17 63.3 4.6 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF469 PF04320.14 CBY15319.1 - 0.043 14.7 1.1 0.058 14.3 1.1 1.2 1 0 0 1 1 1 0 Protein with unknown function (DUF469) DUF2175 PF09943.9 CBY15319.1 - 0.74 10.1 5.2 1.2 9.4 1.6 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) BTB PF00651.31 CBY15320.1 - 1.7e-08 34.7 0.0 3.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CTD_bind PF04818.13 CBY15320.1 - 4.5e-06 27.4 0.1 1.3e-05 26.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. KH_6 PF15985.5 CBY15325.1 - 0.21 12.0 0.7 7.8 6.9 0.0 2.7 3 0 0 3 3 3 0 KH domain Kelch_2 PF07646.15 CBY15327.1 - 0.00014 21.7 3.0 1.1 9.4 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY15327.1 - 0.00066 19.6 6.2 0.0012 18.8 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY15327.1 - 0.04 14.2 2.5 6.9 7.1 0.0 3.7 3 0 0 3 3 3 0 Kelch motif DUF3504 PF12012.8 CBY15328.1 - 6e-11 42.5 0.0 6e-11 42.5 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3504) Uteroglobin PF01099.17 CBY15328.1 - 0.012 15.9 1.2 0.024 14.9 0.6 1.8 2 0 0 2 2 2 0 Uteroglobin family Tetraspanin PF00335.20 CBY15329.1 - 0.043 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF4160 PF13711.6 CBY15330.1 - 0.056 13.8 0.9 0.21 12.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Glyco_hydro_38N PF01074.22 CBY15331.1 - 1.1e-79 267.8 1.5 1.6e-79 267.3 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CBY15331.1 - 3e-22 79.7 0.0 9.1e-21 74.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CBY15331.1 - 1.2e-19 70.3 0.0 3.8e-19 68.6 0.0 2.0 1 0 0 1 1 1 1 Alpha mannosidase middle domain GPS2_interact PF15784.5 CBY15331.1 - 0.14 12.6 0.3 0.5 10.8 0.3 1.8 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain RIBIOP_C PF04950.12 CBY15332.1 - 1.1e-83 281.1 0.5 1.1e-83 281.1 0.5 2.2 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Cyclin_N PF00134.23 CBY15332.1 - 3.8e-35 120.4 1.2 1.5e-34 118.5 0.4 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain AARP2CN PF08142.12 CBY15332.1 - 3e-31 107.4 0.0 2.4e-30 104.4 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain Cyclin_C PF02984.19 CBY15332.1 - 2.8e-22 79.0 3.3 3.1e-22 78.9 0.5 2.6 3 0 0 3 3 3 1 Cyclin, C-terminal domain GTP_EFTU PF00009.27 CBY15332.1 - 3.1e-05 23.6 0.1 0.011 15.3 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY15332.1 - 0.0017 18.4 0.1 0.013 15.5 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY15332.1 - 0.004 17.6 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY15332.1 - 0.021 15.1 0.0 0.068 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBY15332.1 - 0.025 14.6 0.0 0.12 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY15332.1 - 0.027 14.8 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 CBY15332.1 - 0.049 14.1 0.6 0.38 11.3 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 CBY15332.1 - 0.11 12.7 0.0 0.78 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CBY15332.1 - 0.4 10.9 0.0 0.4 10.9 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Pneumo_phosprot PF02478.16 CBY15335.1 - 0.046 13.3 0.8 0.082 12.4 0.8 1.4 1 1 0 1 1 1 0 Pneumovirus phosphoprotein GTP_EFTU PF00009.27 CBY15337.1 - 5.5e-35 120.7 0.0 2.6e-34 118.5 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CBY15337.1 - 1.3e-16 60.6 0.0 3.6e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 CBY15337.1 - 3.9e-16 58.7 0.2 2.1e-15 56.4 0.3 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 CBY15337.1 - 1.6e-06 28.2 0.1 1.4e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CBY15337.1 - 2e-05 24.9 1.0 0.22 11.9 0.0 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Integrin_beta PF00362.18 CBY15338.1 - 6.8e-94 314.2 0.1 1.2e-93 313.3 0.1 1.4 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 CBY15338.1 - 4.3e-15 55.1 0.1 7.7e-15 54.3 0.1 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain PSI_integrin PF17205.3 CBY15338.1 - 2.4e-09 36.8 6.3 2.4e-09 36.8 6.3 3.7 3 0 0 3 3 3 1 Integrin plexin domain EGF_2 PF07974.13 CBY15338.1 - 0.012 16.0 17.3 0.012 16.0 17.3 7.1 5 2 1 6 6 6 0 EGF-like domain I-EGF_1 PF18372.1 CBY15338.1 - 0.018 15.1 10.8 0.018 15.1 10.8 6.3 5 1 0 5 5 5 0 Integrin beta epidermal growth factor like domain 1 VWA PF00092.28 CBY15338.1 - 0.13 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain MIR PF02815.19 CBY15339.1 - 1.1e-12 48.1 0.4 5.9e-12 45.8 0.4 1.8 1 1 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.11 CBY15339.1 - 0.0015 17.8 0.0 0.018 14.2 0.0 2.2 2 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor HIT PF01230.23 CBY15340.1 - 2.1e-25 89.3 0.0 2.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBY15340.1 - 1.2e-08 35.4 0.0 1.7e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CBY15340.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Arf PF00025.21 CBY15341.1 - 7.8e-79 263.2 0.1 8.9e-79 263.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBY15341.1 - 8.3e-15 54.7 0.0 9.2e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CBY15341.1 - 2.6e-14 53.5 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY15341.1 - 1.8e-12 47.2 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY15341.1 - 7.8e-12 45.0 1.2 8.1e-08 31.8 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY15341.1 - 1.6e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY15341.1 - 1.5e-05 25.0 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBY15341.1 - 0.0022 17.3 0.2 0.017 14.4 0.1 1.9 2 0 0 2 2 2 1 6-phosphofructo-2-kinase MoaC PF01967.21 CBY15342.1 - 9.1e-50 168.3 0.4 1e-49 168.1 0.4 1.0 1 0 0 1 1 1 1 MoaC family Ribosomal_L4 PF00573.22 CBY15342.1 - 0.072 12.8 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Pkinase PF00069.25 CBY15343.1 - 2.3e-09 37.0 0.0 3.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15343.1 - 1.5e-06 27.7 0.0 1.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCCH PF00642.24 CBY15343.1 - 0.79 9.7 3.7 0.49 10.4 1.2 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cupin_8 PF13621.6 CBY15345.1 - 5e-32 111.6 0.0 7.3e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY15345.1 - 9.4e-06 25.3 0.0 3.5e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 CBY15345.1 - 0.0095 15.6 0.0 0.034 13.8 0.0 1.8 2 0 0 2 2 2 1 Cupin JmjC PF02373.22 CBY15345.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase PS_Dcarbxylase PF02666.15 CBY15346.1 - 7.3e-65 218.3 0.0 8.6e-65 218.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.22 CBY15346.1 - 0.036 14.3 0.0 5.4 7.3 0.0 3.0 2 1 1 3 3 3 0 Peptidase family M23 Suppressor_APC PF11414.8 CBY15347.1 - 0.073 13.1 0.8 0.2 11.7 0.8 1.7 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Terminase_6C PF17289.2 CBY15347.1 - 0.39 10.8 2.6 0.78 9.8 1.3 1.9 1 1 0 2 2 2 0 Terminase RNaseH-like domain OLF PF02191.16 CBY15348.1 - 2.4e-79 266.4 7.2 3.8e-79 265.8 7.2 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain DUF5074 PF16819.5 CBY15348.1 - 0.2 11.7 5.5 0.92 9.6 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) APC_N_CC PF16689.5 CBY15348.1 - 1.6 8.8 4.5 26 5.0 0.1 2.9 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain zf-DNL PF05180.12 CBY15349.1 - 0.046 13.7 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 DNL zinc finger Macoilin PF09726.9 CBY15350.1 - 0.36 9.4 9.0 0.45 9.0 9.0 1.2 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CBY15350.1 - 2.3 5.2 10.5 2.8 4.9 10.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 CBY15352.1 - 8.7e-78 261.3 0.0 9.9e-78 261.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15352.1 - 3.5e-38 131.4 0.0 4e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY15352.1 - 2.6e-08 33.5 0.0 3.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY15352.1 - 3.8e-05 23.2 0.0 8.2e-05 22.1 0.0 1.5 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY15352.1 - 0.00054 18.8 0.0 0.00084 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBY15352.1 - 0.0039 16.8 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY15352.1 - 0.024 14.5 0.0 0.2 11.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kelch_4 PF13418.6 CBY15355.1 - 7.9e-06 25.8 0.8 0.0031 17.5 0.1 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY15355.1 - 2.7e-05 24.3 2.9 0.016 15.5 0.2 2.7 2 1 1 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CBY15355.1 - 0.51 10.0 7.5 0.17 11.5 1.4 3.2 4 1 0 4 4 4 0 Kelch motif CUB PF00431.20 CBY15356.1 - 6.5e-11 42.5 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 CUB domain DUF3887 PF13026.6 CBY15356.1 - 0.13 13.1 0.0 3.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) Serpin PF00079.20 CBY15357.1 - 1.5e-36 126.6 4.3 1.8e-36 126.3 4.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) NAD_binding_10 PF13460.6 CBY15357.1 - 0.083 12.8 0.1 0.43 10.4 0.0 1.9 1 1 1 2 2 2 0 NAD(P)H-binding DUF3810 PF12725.7 CBY15358.1 - 0.058 12.7 0.1 0.073 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ATG27 PF09451.10 CBY15358.1 - 0.1 12.5 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Serpin PF00079.20 CBY15359.1 - 1.7e-74 251.4 5.6 1.9e-74 251.2 5.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Zona_pellucida PF00100.23 CBY15361.1 - 2.5e-27 96.3 0.3 3.3e-27 95.9 0.3 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain ECSCR PF15820.5 CBY15361.1 - 0.075 12.9 0.7 0.13 12.1 0.7 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Glyoxalase_2 PF12681.7 CBY15362.1 - 0.042 13.8 0.4 0.054 13.4 0.4 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain V-set PF07686.17 CBY15363.1 - 0.0027 17.8 0.0 0.0031 17.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Kelch_2 PF07646.15 CBY15365.1 - 6.3e-07 29.1 1.9 1.5 8.9 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 CBY15365.1 - 4.7e-05 23.5 9.2 0.22 11.9 0.0 5.9 7 1 1 8 8 8 2 Kelch motif Kelch_4 PF13418.6 CBY15365.1 - 0.00015 21.7 0.1 14 5.8 0.0 4.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY15365.1 - 0.053 13.1 0.3 34 4.1 0.0 3.8 4 0 0 4 4 4 0 Kelch motif DUF5122 PF17164.4 CBY15365.1 - 0.059 13.7 0.7 51 4.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller DUF1905 PF08922.11 CBY15365.1 - 0.082 13.0 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) RHH_4 PF13467.6 CBY15365.1 - 0.098 12.6 0.3 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain DUF3439 PF11921.8 CBY15366.1 - 0.017 15.1 1.1 0.035 14.1 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RIIa PF02197.17 CBY15367.1 - 0.1 12.3 1.8 0.12 12.1 0.3 2.0 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Kelch_6 PF13964.6 CBY15368.1 - 0.0044 17.3 0.7 3 8.3 0.0 3.8 3 1 1 4 4 4 1 Kelch motif Kelch_2 PF07646.15 CBY15368.1 - 0.014 15.4 0.6 12 6.0 0.1 3.6 3 0 0 3 3 3 0 Kelch motif Phage_integrase PF00589.22 CBY15369.1 - 1.2e-09 38.2 0.0 2.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family SRP-alpha_N PF04086.13 CBY15369.1 - 0.95 9.3 15.3 1.8 8.4 15.3 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal IBN_N PF03810.19 CBY15370.1 - 0.012 15.5 0.8 0.89 9.5 0.0 2.9 2 1 0 2 2 2 0 Importin-beta N-terminal domain PRANC PF09372.10 CBY15370.1 - 0.019 15.3 0.2 0.072 13.4 0.1 2.0 1 1 1 2 2 2 0 PRANC domain Put_Phosphatase PF06888.12 CBY15370.1 - 0.082 12.3 0.4 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase PS_Dcarbxylase PF02666.15 CBY15371.1 - 2e-31 109.1 0.0 2.4e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PIF PF05092.12 CBY15371.1 - 0.21 10.3 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Per os infectivity Kelch_2 PF07646.15 CBY15372.1 - 0.00023 21.0 1.1 0.73 9.9 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY15372.1 - 0.023 14.7 0.0 0.023 14.7 0.0 3.2 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 CBY15372.1 - 0.05 13.9 5.1 13 6.2 0.0 3.7 3 1 1 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CBY15373.1 - 0.017 15.1 2.2 2.5 8.2 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY15373.1 - 0.051 13.9 0.2 24 5.4 0.0 3.5 3 0 0 3 3 3 0 Kelch motif GMC_oxred_N PF00732.19 CBY15374.1 - 3.5e-62 210.5 0.4 2.2e-38 132.3 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CBY15374.1 - 1.1e-39 136.3 0.1 1.9e-39 135.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CBY15374.1 - 8.4e-05 21.8 0.0 0.00016 20.9 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 CBY15374.1 - 0.00032 20.4 0.5 0.00079 19.1 0.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBY15374.1 - 0.00042 20.5 0.1 0.0012 19.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBY15374.1 - 0.001 18.3 0.1 0.011 14.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CBY15374.1 - 0.0024 17.2 0.0 0.015 14.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBY15374.1 - 0.062 12.0 0.1 0.2 10.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 CBY15374.1 - 0.078 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 CBY15374.1 - 0.11 12.1 0.4 0.8 9.3 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 CBY15374.1 - 0.14 12.4 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain FmdE PF02663.14 CBY15376.1 - 0.13 12.3 4.3 0.2 11.7 3.8 1.7 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon CPL PF08144.11 CBY15377.1 - 1e-20 74.5 0.3 1e-20 74.5 0.3 4.2 4 2 0 4 4 4 1 CPL (NUC119) domain DUF4874 PF16173.5 CBY15377.1 - 0.12 12.0 2.4 1.5 8.5 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4874) HsdM_N PF12161.8 CBY15377.1 - 6 7.5 15.0 48 4.6 11.4 3.0 2 1 0 2 2 2 0 HsdM N-terminal domain WD40 PF00400.32 CBY15378.1 - 9.4e-36 121.2 12.0 8.8e-10 39.0 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY15378.1 - 6.7e-16 58.4 0.3 3.8e-05 23.9 0.1 5.4 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 CBY15378.1 - 4.5e-14 51.7 0.2 1e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 CBY15378.1 - 6.9e-06 25.3 0.5 0.94 8.4 0.0 4.8 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY15378.1 - 0.0012 17.6 0.3 2.7 6.5 0.0 3.9 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 CBY15378.1 - 0.031 13.6 0.1 0.48 9.7 0.0 2.7 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal LEA_4 PF02987.16 CBY15378.1 - 0.11 12.5 1.2 0.23 11.6 1.2 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein Thioredoxin PF00085.20 CBY15379.1 - 1.5e-56 188.8 0.6 1e-30 105.7 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CBY15379.1 - 1.2e-08 35.3 2.0 0.0004 20.8 0.2 3.7 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY15379.1 - 4.8e-08 33.1 0.1 0.0032 17.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CBY15379.1 - 6.2e-08 32.9 0.1 0.03 14.6 0.0 3.7 3 1 1 4 4 4 3 Thioredoxin-like AhpC-TSA PF00578.21 CBY15379.1 - 3.1e-07 30.3 0.2 0.032 14.2 0.0 2.5 2 1 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 CBY15379.1 - 8.3e-06 25.4 0.0 0.0087 15.4 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 CBY15379.1 - 0.001 19.2 0.6 0.16 12.1 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 CBY15379.1 - 0.0016 18.1 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 Redoxin Thioredoxin_3 PF13192.6 CBY15379.1 - 0.005 16.9 0.3 0.57 10.3 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin domain Calsequestrin PF01216.17 CBY15379.1 - 0.0078 15.3 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 Calsequestrin TraF PF13728.6 CBY15379.1 - 0.067 13.0 0.0 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Sulfotransfer_1 PF00685.27 CBY15380.1 - 1.6e-12 47.5 0.1 2.8e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY15380.1 - 0.0018 18.7 0.1 0.3 11.4 0.0 2.7 1 1 1 3 3 3 1 Sulfotransferase family DUF5545 PF17699.1 CBY15384.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5545) LIM_bind PF01803.16 CBY15386.1 - 1.5e-39 136.0 2.1 2.7e-29 102.4 0.3 2.3 1 1 1 2 2 2 2 LIM-domain binding protein LID PF17916.1 CBY15386.1 - 1.7e-05 24.4 1.2 3.6e-05 23.3 1.2 1.6 1 0 0 1 1 1 1 LIM interaction domain (LID) ATP-gua_Ptrans PF00217.19 CBY15386.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain Gal-3-0_sulfotr PF06990.11 CBY15387.1 - 4.2e-12 45.7 0.0 4.2e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase FAM209 PF15206.6 CBY15387.1 - 0.011 15.5 0.2 0.013 15.2 0.2 1.2 1 0 0 1 1 1 0 FAM209 family LptF_LptG PF03739.14 CBY15387.1 - 0.033 13.1 0.1 0.04 12.8 0.1 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG EF-hand_7 PF13499.6 CBY15388.1 - 8.6e-25 87.0 4.2 2.4e-15 56.8 0.5 3.3 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBY15388.1 - 1.3e-24 83.8 7.1 5.4e-07 28.7 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBY15388.1 - 4.1e-22 76.2 3.3 6.2e-06 25.7 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBY15388.1 - 3.1e-19 67.5 8.5 4.1e-06 26.0 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY15388.1 - 8.8e-14 51.1 8.2 3e-06 27.0 0.3 4.3 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY15388.1 - 0.00012 22.4 0.6 6.4 7.1 0.0 3.2 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY15388.1 - 0.00019 21.4 2.2 3.5 7.6 0.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CBY15388.1 - 0.002 18.4 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 CBY15388.1 - 0.0085 16.0 1.1 15 5.4 0.0 3.3 2 1 2 4 4 4 0 Caleosin related protein Homeodomain PF00046.29 CBY15388.1 - 0.027 14.3 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain Homez PF11569.8 CBY15388.1 - 0.031 13.7 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Dockerin_1 PF00404.18 CBY15388.1 - 0.052 13.8 0.0 5.4 7.3 0.0 2.9 3 0 0 3 3 3 0 Dockerin type I domain S10_plectin PF03501.15 CBY15388.1 - 0.082 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain PMBR PF09373.10 CBY15388.1 - 0.19 11.9 0.0 68 3.9 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat Dynamin_M PF01031.20 CBY15389.1 - 5.4e-96 321.2 3.1 5.4e-96 321.2 3.1 2.4 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 CBY15389.1 - 1.4e-55 187.9 0.1 8.8e-55 185.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CBY15389.1 - 1.7e-22 79.4 3.9 1.7e-22 79.4 3.9 2.8 3 0 0 3 3 3 1 Dynamin GTPase effector domain PH PF00169.29 CBY15389.1 - 8.2e-09 35.9 0.2 1.7e-08 34.9 0.2 1.5 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 CBY15389.1 - 0.00013 22.0 0.0 0.00044 20.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase DASH_Duo1 PF08651.10 CBY15389.1 - 0.016 14.9 0.7 3.5 7.5 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF3206 PF11472.8 CBY15389.1 - 0.03 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) AAA_28 PF13521.6 CBY15389.1 - 0.075 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain LIM PF00412.22 CBY15390.1 - 1.9e-36 124.1 39.0 3.3e-14 52.8 8.4 3.5 4 0 0 4 4 4 3 LIM domain PDZ PF00595.24 CBY15390.1 - 3.3e-11 43.4 0.0 6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY15390.1 - 0.00081 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY15390.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain SPC25 PF06703.11 CBY15392.1 - 1.4e-34 119.3 0.9 1.6e-34 119.0 0.9 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2157 PF09925.9 CBY15393.1 - 9.2 6.0 8.0 1.9 8.3 2.2 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) PfkB PF00294.24 CBY15394.1 - 7.1e-37 127.3 0.2 8.5e-37 127.1 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Telomere_reg-2 PF10193.9 CBY15395.1 - 2.3e-08 34.5 0.3 4.5e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 Telomere length regulation protein SecA_DEAD PF07517.14 CBY15395.1 - 0.072 12.4 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain PLAT PF01477.23 CBY15396.1 - 0.025 15.1 0.0 0.028 15.0 0.0 1.1 1 0 0 1 1 1 0 PLAT/LH2 domain PfkB PF00294.24 CBY15397.1 - 3.1e-40 138.4 0.0 3.6e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_L7Ae PF01248.26 CBY15397.1 - 0.085 12.6 0.3 0.26 11.0 0.0 2.0 2 1 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Telomere_reg-2 PF10193.9 CBY15398.1 - 2e-08 34.6 0.3 3.7e-08 33.8 0.3 1.4 1 0 0 1 1 1 1 Telomere length regulation protein SecA_DEAD PF07517.14 CBY15398.1 - 0.061 12.6 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Sulfotransfer_2 PF03567.14 CBY15399.1 - 0.034 14.1 0.2 0.047 13.6 0.2 1.3 1 0 0 1 1 1 0 Sulfotransferase family EzrA PF06160.12 CBY15400.1 - 0.00012 20.4 11.0 0.0028 15.9 0.7 2.1 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 CBY15400.1 - 0.00022 21.2 16.5 0.0011 19.1 4.9 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 CBY15400.1 - 0.00032 19.7 15.4 0.00081 18.4 8.1 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein BLOC1_2 PF10046.9 CBY15400.1 - 0.00043 20.5 10.2 0.42 11.0 0.1 3.9 1 1 3 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 CBY15400.1 - 0.00057 20.2 4.3 0.00057 20.2 4.3 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 CBY15400.1 - 0.0014 18.8 14.0 0.12 12.6 0.5 3.2 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding GIT_CC PF16559.5 CBY15400.1 - 0.002 17.9 5.0 0.38 10.6 0.3 3.8 3 1 1 4 4 3 2 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 CBY15400.1 - 0.0036 17.5 13.0 0.12 12.5 3.6 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus HAUS5 PF14817.6 CBY15400.1 - 0.0039 16.0 5.6 0.0059 15.4 1.6 2.0 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 5 bZIP_Maf PF03131.17 CBY15400.1 - 0.0052 17.3 6.9 0.41 11.2 0.3 3.2 2 1 1 3 3 3 1 bZIP Maf transcription factor Cast PF10174.9 CBY15400.1 - 0.006 14.9 9.3 0.0073 14.6 9.3 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Occludin_ELL PF07303.13 CBY15400.1 - 0.0073 17.0 5.5 0.45 11.3 0.1 2.5 1 1 0 2 2 2 1 Occludin homology domain JIP_LZII PF16471.5 CBY15400.1 - 0.0095 16.1 17.6 0.72 10.1 1.1 4.2 1 1 2 3 3 3 1 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 CBY15400.1 - 0.01 15.9 3.8 0.17 11.9 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CBY15400.1 - 0.011 16.3 11.1 0.011 16.3 11.1 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 CBY15400.1 - 0.011 16.2 22.3 0.048 14.1 2.6 3.4 1 1 1 3 3 3 0 Cell division protein ZapB KASH_CCD PF14662.6 CBY15400.1 - 0.012 15.5 16.2 0.17 11.7 8.3 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HIP1_clath_bdg PF16515.5 CBY15400.1 - 0.012 16.2 9.2 0.53 10.9 3.5 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 CBY15400.1 - 0.016 15.7 1.1 0.24 11.9 0.1 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 CBY15400.1 - 0.017 15.3 1.9 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 CBY15400.1 - 0.02 15.5 13.3 0.15 12.7 1.0 3.2 1 1 2 3 3 3 0 Initiation control protein YabA Golgin_A5 PF09787.9 CBY15400.1 - 0.023 14.2 11.0 0.048 13.1 9.7 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 CLZ PF16526.5 CBY15400.1 - 0.024 15.0 2.3 0.024 15.0 2.3 2.4 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2205 PF10224.9 CBY15400.1 - 0.03 14.3 9.1 0.25 11.4 0.4 3.0 1 1 2 3 3 3 0 Short coiled-coil protein GrpE PF01025.19 CBY15400.1 - 0.036 13.7 14.0 0.046 13.4 1.6 2.8 1 1 1 2 2 2 0 GrpE DUF4201 PF13870.6 CBY15400.1 - 0.045 13.5 9.0 0.2 11.4 3.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4472 PF14739.6 CBY15400.1 - 0.046 14.5 11.0 0.66 10.7 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Syntaxin_2 PF14523.6 CBY15400.1 - 0.047 14.1 6.2 2.6 8.4 1.6 3.0 2 1 1 3 3 3 0 Syntaxin-like protein HemX PF04375.14 CBY15400.1 - 0.049 12.9 3.1 0.047 13.0 0.8 1.8 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Laminin_II PF06009.12 CBY15400.1 - 0.05 13.6 2.4 2.1 8.3 0.1 2.8 1 1 1 3 3 3 0 Laminin Domain II Cnn_1N PF07989.11 CBY15400.1 - 0.054 13.7 13.3 0.27 11.4 1.5 3.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Sec34 PF04136.15 CBY15400.1 - 0.061 13.2 6.5 0.96 9.3 0.8 2.8 1 1 2 3 3 3 0 Sec34-like family Sec8_exocyst PF04048.14 CBY15400.1 - 0.063 13.2 4.6 7.4 6.5 0.4 3.1 1 1 1 3 3 3 0 Sec8 exocyst complex component specific domain AAA_13 PF13166.6 CBY15400.1 - 0.064 11.9 7.2 0.099 11.3 7.2 1.3 1 1 0 1 1 1 0 AAA domain MAD PF05557.13 CBY15400.1 - 0.069 11.5 11.6 0.13 10.6 11.6 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein GARP PF16731.5 CBY15400.1 - 0.074 12.7 5.5 0.085 12.5 4.6 1.6 1 1 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF2730 PF10805.8 CBY15400.1 - 0.075 13.1 2.2 0.29 11.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TolA_bind_tri PF16331.5 CBY15400.1 - 0.076 13.1 10.0 0.94 9.6 4.1 3.4 2 1 1 3 3 2 0 TolA binding protein trimerisation Nup54 PF13874.6 CBY15400.1 - 0.082 13.0 5.5 0.25 11.4 0.7 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Spectrin PF00435.21 CBY15400.1 - 0.095 13.2 10.5 1.8 9.1 2.2 3.1 1 1 2 3 3 3 0 Spectrin repeat Seryl_tRNA_N PF02403.22 CBY15400.1 - 0.1 12.8 11.3 1 9.6 1.7 2.8 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CALCOCO1 PF07888.11 CBY15400.1 - 0.1 11.4 12.4 0.25 10.1 12.4 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 CBY15400.1 - 0.11 12.7 19.7 1.8 8.7 0.5 4.1 2 1 2 4 4 4 0 bZIP transcription factor NPA PF16469.5 CBY15400.1 - 0.12 12.9 8.3 0.052 14.1 4.2 2.3 1 1 1 2 2 2 0 Nematode polyprotein allergen ABA-1 DUF3450 PF11932.8 CBY15400.1 - 0.12 11.6 8.9 0.33 10.2 4.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 CBY15400.1 - 0.14 11.8 9.8 0.084 12.6 4.4 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 COG2 PF06148.11 CBY15400.1 - 0.16 12.1 6.7 1.3 9.1 0.9 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Hormone_1 PF00103.20 CBY15400.1 - 0.17 11.6 1.3 0.63 9.7 0.0 2.3 1 1 1 2 2 2 0 Somatotropin hormone family ADIP PF11559.8 CBY15400.1 - 0.18 11.9 8.6 0.42 10.7 2.3 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 CBY15400.1 - 0.19 11.4 10.2 0.083 12.5 5.7 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 CBY15400.1 - 0.19 12.1 11.9 0.052 14.0 5.8 2.2 1 1 1 2 2 2 0 Fez1 Prefoldin_2 PF01920.20 CBY15400.1 - 0.21 11.5 18.8 0.4 10.7 0.6 3.7 1 1 3 4 4 4 0 Prefoldin subunit Med9 PF07544.13 CBY15400.1 - 0.24 11.5 7.4 2.8 8.1 0.1 3.3 2 1 2 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.19 CBY15400.1 - 0.24 9.3 5.2 0.4 8.5 4.6 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.6 CBY15400.1 - 0.26 11.7 7.0 1.2 9.6 1.8 2.7 1 1 0 2 2 2 0 Snapin/Pallidin DUF2203 PF09969.9 CBY15400.1 - 0.26 12.0 6.8 2.3 9.0 0.4 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4795 PF16043.5 CBY15400.1 - 0.3 10.6 12.6 1.1e+02 2.4 12.5 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) RmuC PF02646.16 CBY15400.1 - 0.31 10.1 7.7 0.27 10.3 0.6 2.7 1 1 1 3 3 3 0 RmuC family THOC7 PF05615.13 CBY15400.1 - 0.33 11.2 14.7 0.7 10.2 0.7 2.8 1 1 1 2 2 2 0 Tho complex subunit 7 OmpH PF03938.14 CBY15400.1 - 0.33 11.3 13.6 98 3.3 13.5 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 CBY15400.1 - 0.38 11.3 5.5 21 5.8 3.6 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc24 PF08286.11 CBY15400.1 - 0.39 11.0 11.3 2.6 8.3 1.9 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HrpB7 PF09486.10 CBY15400.1 - 0.43 10.9 6.7 1.5 9.2 1.5 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) LMBR1 PF04791.16 CBY15400.1 - 0.47 9.3 4.5 0.98 8.3 4.4 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein AATF-Che1 PF13339.6 CBY15400.1 - 0.49 11.1 4.7 1.2 9.8 0.7 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Prominin PF05478.11 CBY15400.1 - 0.57 8.1 2.5 0.72 7.7 1.1 1.6 1 1 0 1 1 1 0 Prominin Herpes_BLRF2 PF05812.12 CBY15400.1 - 0.6 10.3 5.7 7.5 6.7 0.3 3.0 2 1 1 3 3 2 0 Herpesvirus BLRF2 protein Jnk-SapK_ap_N PF09744.9 CBY15400.1 - 0.62 10.3 17.7 0.39 10.9 6.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF5082 PF16888.5 CBY15400.1 - 0.63 10.3 10.4 4.1 7.7 1.8 3.5 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF4559 PF15112.6 CBY15400.1 - 0.64 9.7 5.1 0.84 9.3 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) K-box PF01486.17 CBY15400.1 - 0.65 10.2 9.7 1.9 8.7 0.2 3.7 2 1 1 3 3 3 0 K-box region Ax_dynein_light PF10211.9 CBY15400.1 - 0.69 9.8 15.2 0.92 9.4 1.2 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain UPF0449 PF15136.6 CBY15400.1 - 0.69 10.4 13.1 4.6 7.8 0.7 3.7 1 1 1 3 3 3 0 Uncharacterised protein family UPF0449 GAS PF13851.6 CBY15400.1 - 0.72 9.2 12.4 27 4.0 0.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 CBY15400.1 - 0.74 10.3 7.2 6.8 7.2 7.2 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF724 PF05266.14 CBY15400.1 - 0.85 9.4 10.1 2 8.2 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Sipho_Gp157 PF05565.11 CBY15400.1 - 0.87 9.6 13.4 0.51 10.3 7.0 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 PI3K_P85_iSH2 PF16454.5 CBY15400.1 - 0.92 9.1 12.5 34 4.0 12.5 2.3 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4200 PF13863.6 CBY15400.1 - 1 9.8 17.2 13 6.2 8.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ERM PF00769.19 CBY15400.1 - 1.1 9.0 16.5 1.8 8.3 5.9 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4349 PF14257.6 CBY15400.1 - 1.1 8.6 4.6 0.5 9.8 0.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) TSC22 PF01166.18 CBY15400.1 - 1.2 9.5 15.2 5.7 7.3 1.4 4.4 3 2 1 4 4 4 0 TSC-22/dip/bun family FlaC_arch PF05377.11 CBY15400.1 - 1.2 9.6 7.7 2.1 8.8 0.9 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CBY15400.1 - 1.4 8.8 13.3 5.2 6.9 0.3 3.6 2 1 3 5 5 5 0 Septum formation initiator Lipoprotein_20 PF13942.6 CBY15400.1 - 1.4 8.8 4.8 8.1 6.3 1.4 2.3 1 1 1 2 2 2 0 YfhG lipoprotein TMPIT PF07851.13 CBY15400.1 - 1.5 8.0 6.2 0.76 9.0 0.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein Atg14 PF10186.9 CBY15400.1 - 1.5 7.8 8.6 0.41 9.7 3.2 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ead_Ea22 PF13935.6 CBY15400.1 - 1.6 9.4 8.7 22 5.7 8.7 2.2 1 1 0 1 1 1 0 Ead/Ea22-like protein HAUS-augmin3 PF14932.6 CBY15400.1 - 2.1 7.9 12.5 1.2 8.7 6.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Rx_N PF18052.1 CBY15400.1 - 2.1 8.6 5.5 23 5.3 5.5 2.6 1 1 0 1 1 1 0 Rx N-terminal domain CC2-LZ PF16516.5 CBY15400.1 - 2.5 8.5 12.3 5 7.5 5.7 3.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DegS PF05384.11 CBY15400.1 - 3 7.3 12.2 0.54 9.7 1.6 2.9 1 1 1 3 3 3 0 Sensor protein DegS DUF4047 PF13256.6 CBY15400.1 - 3 8.0 6.8 17 5.6 0.8 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) CENP-Q PF13094.6 CBY15400.1 - 3.8 7.7 15.8 0.08 13.1 1.3 2.7 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TLE_N PF03920.15 CBY15400.1 - 4 7.5 7.9 16 5.5 0.7 2.9 1 1 2 3 3 3 0 Groucho/TLE N-terminal Q-rich domain BRE1 PF08647.11 CBY15400.1 - 5 7.3 9.4 0.38 10.9 0.7 2.9 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase CENP-H PF05837.12 CBY15400.1 - 5.2 7.5 9.2 6.7 7.2 2.7 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2381 PF09544.10 CBY15400.1 - 7.6 6.0 6.1 5.6 6.4 0.1 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2381) Swi5 PF07061.11 CBY15400.1 - 9.3 6.4 10.2 11 6.2 0.6 3.4 1 1 1 2 2 2 0 Swi5 AMPKBI PF04739.15 CBY15401.1 - 2.2e-21 75.9 0.9 6e-21 74.5 0.9 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CBY15401.1 - 1.7e-20 73.0 0.0 2.7e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 CBY15401.1 - 0.02 15.4 0.0 0.04 14.5 0.0 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Tcp10_C PF07202.13 CBY15402.1 - 1.1e-62 211.1 7.2 1.1e-62 211.1 7.2 1.8 2 0 0 2 2 2 1 T-complex protein 10 C-terminus ZapB PF06005.12 CBY15402.1 - 0.95 10.0 8.8 2 8.9 8.8 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Polo_box_3 PF18544.1 CBY15402.1 - 1.1 9.9 6.4 2.2 9.0 0.0 3.8 3 1 1 4 4 4 0 Polo box domain OmpH PF03938.14 CBY15402.1 - 2.4 8.5 13.2 5.1 7.4 6.0 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) LMBR1 PF04791.16 CBY15402.1 - 4.3 6.1 8.8 5.8 5.7 8.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Jnk-SapK_ap_N PF09744.9 CBY15402.1 - 9.1 6.5 14.2 17 5.6 14.2 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Mod_r PF07200.13 CBY15404.1 - 2.7e-33 115.1 10.8 3.5e-33 114.8 10.8 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 CBY15404.1 - 0.56 9.0 11.0 0.55 9.0 10.3 1.2 1 1 0 1 1 1 0 Spc7 kinetochore protein RMI2 PF16100.5 CBY15406.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 DUF333 PF03891.15 CBY15406.1 - 0.018 15.3 0.3 0.069 13.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF333) Rho_RNA_bind PF07497.12 CBY15406.1 - 0.097 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain NYN PF01936.18 CBY15407.1 - 0.057 13.9 0.0 0.075 13.5 0.0 1.2 1 0 0 1 1 1 0 NYN domain Filament PF00038.21 CBY15408.1 - 2.2e-89 300.1 46.9 3e-89 299.7 46.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 CBY15408.1 - 2.2e-08 34.2 44.5 0.0021 18.1 16.0 4.8 3 1 0 3 3 3 3 TPR/MLP1/MLP2-like protein Filament_head PF04732.14 CBY15408.1 - 0.0023 18.8 8.3 0.0023 18.8 8.3 3.1 3 1 1 4 4 3 1 Intermediate filament head (DNA binding) region GAS PF13851.6 CBY15408.1 - 0.0027 17.1 44.9 0.36 10.1 2.7 3.3 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CBY15408.1 - 0.0079 15.1 40.0 0.078 11.9 10.5 2.6 1 1 1 2 2 2 2 Spc7 kinetochore protein RNR_N PF08343.10 CBY15408.1 - 0.028 14.4 8.8 0.9 9.6 0.4 2.8 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal DUF1664 PF07889.12 CBY15408.1 - 0.042 13.9 20.6 1.9 8.5 3.1 4.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) FAM184 PF15665.5 CBY15408.1 - 0.043 13.6 41.0 2.6 7.8 14.9 3.5 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B NPV_P10 PF05531.12 CBY15408.1 - 0.096 13.2 8.0 0.77 10.3 0.1 4.4 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 CBY15408.1 - 0.16 11.4 42.6 0.98 8.8 11.8 2.8 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF3698 PF12479.8 CBY15408.1 - 0.29 11.7 5.5 0.34 11.5 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3698) CCDC92 PF14916.6 CBY15408.1 - 0.46 10.3 13.8 0.74 9.6 0.0 4.8 5 0 0 5 5 4 0 Coiled-coil domain of unknown function Baculo_PEP_C PF04513.12 CBY15408.1 - 0.96 9.5 9.3 2.1 8.4 2.7 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4515 PF14988.6 CBY15408.1 - 1.3 8.9 40.6 0.21 11.4 2.8 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) PSI_PsaF PF02507.15 CBY15408.1 - 1.4 8.8 5.6 20 5.0 0.0 3.8 3 1 3 6 6 6 0 Photosystem I reaction centre subunit III Taxilin PF09728.9 CBY15408.1 - 1.5 7.9 43.4 0.74 8.9 12.6 2.3 1 1 1 2 2 2 0 Myosin-like coiled-coil protein BLOC1_2 PF10046.9 CBY15408.1 - 1.9 8.9 35.6 0.12 12.7 3.9 5.4 3 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KASH_CCD PF14662.6 CBY15408.1 - 2.9 7.7 44.0 0.049 13.5 13.3 4.1 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 CBY15408.1 - 4 7.5 43.5 0.45 10.5 2.3 4.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 CBY15408.1 - 4.7 7.0 13.3 0.2 11.4 2.8 2.8 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin_2 PF14523.6 CBY15408.1 - 6 7.3 21.6 0.054 13.9 3.6 4.1 1 1 1 2 2 1 0 Syntaxin-like protein V_ATPase_I PF01496.19 CBY15408.1 - 6.4 4.5 32.0 3.1 5.6 13.7 2.7 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.11 CBY15408.1 - 6.5 6.2 16.3 0.72 9.3 1.8 3.2 1 1 4 5 5 5 0 Allexivirus 40kDa protein ADIP PF11559.8 CBY15408.1 - 6.9 6.7 39.1 1.3 9.1 6.3 4.7 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 CBY15408.1 - 6.9 6.8 43.1 0.72 9.9 7.5 5.2 3 2 2 5 5 5 0 Designed helical repeat protein 10 domain Mt_ATP-synt_D PF05873.12 CBY15408.1 - 7.5 6.4 23.6 0.7 9.7 2.9 3.6 1 1 3 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) Collectrin PF16959.5 CBY15409.1 - 1e-05 25.4 0.1 1.6e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 Renal amino acid transporter COX7a PF02238.15 CBY15409.1 - 0.0046 17.3 0.2 0.0088 16.4 0.2 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII NusA_N PF08529.11 CBY15409.1 - 0.03 14.7 0.5 0.088 13.2 0.1 1.8 2 0 0 2 2 2 0 NusA N-terminal domain BtpA PF03437.15 CBY15410.1 - 6.3e-57 192.9 0.1 7.1e-57 192.7 0.1 1.0 1 0 0 1 1 1 1 BtpA family Chromo_shadow PF01393.19 CBY15411.1 - 6.9e-24 83.7 3.9 6.6e-23 80.6 0.0 2.8 3 0 0 3 3 3 1 Chromo shadow domain Chromo PF00385.24 CBY15411.1 - 5.2e-18 64.7 0.9 3e-14 52.7 0.9 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CBY15411.1 - 0.0031 17.6 0.3 0.057 13.6 0.1 2.3 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 DUF3013 PF11217.8 CBY15411.1 - 0.029 14.2 0.0 0.071 13.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3013) Tudor-knot PF11717.8 CBY15411.1 - 0.035 14.0 0.7 0.26 11.2 0.2 2.2 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Peptidase_A22B PF04258.13 CBY15412.1 - 2.5e-51 174.9 6.0 3.4e-51 174.5 6.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CBY15412.1 - 1.6e-05 24.5 8.2 1.8e-05 24.3 7.2 1.6 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease MFS_1 PF07690.16 CBY15413.1 - 1.8e-13 50.2 1.5 2.1e-13 49.9 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CBY15413.1 - 0.00084 18.7 0.9 0.0012 18.2 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 CBY15413.1 - 0.0092 14.7 0.3 0.013 14.2 0.2 1.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like UL20 PF17582.2 CBY15413.1 - 0.033 13.5 0.1 0.053 12.8 0.1 1.3 1 1 0 1 1 1 0 Cytomegalovirus UL20 MscL PF01741.18 CBY15413.1 - 0.052 13.8 0.1 0.09 13.1 0.1 1.4 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL 7TMR-DISM_7TM PF07695.11 CBY15413.1 - 0.25 11.2 9.4 5.2 6.9 9.4 2.0 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF202 PF02656.15 CBY15413.1 - 1.1 9.8 5.0 5.3 7.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Phage_integrase PF00589.22 CBY15415.1 - 3.7e-08 33.4 0.0 6.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family SpoVG PF04026.12 CBY15415.1 - 1.6e-05 25.0 0.1 3.5e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 SpoVG Bclt PF15318.6 CBY15415.1 - 0.1 12.4 0.9 0.22 11.3 0.9 1.5 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis DNA_pol_B_2 PF03175.13 CBY15417.1 - 1.1e-13 50.9 2.6 2.1e-06 26.9 0.1 2.7 3 0 0 3 3 3 2 DNA polymerase type B, organellar and viral DNA_topoisoIV PF00521.20 CBY15418.1 - 0.00043 19.3 1.2 0.0005 19.1 1.2 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A CaMKII_AD PF08332.10 CBY15422.1 - 7.7e-20 71.3 0.0 1.1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain zf-C2H2 PF00096.26 CBY15423.1 - 0.019 15.4 19.8 0.036 14.5 5.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY15423.1 - 0.11 13.4 4.7 0.11 13.4 4.7 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger LLGL PF08366.13 CBY15424.1 - 7.2e-12 45.6 0.0 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 LLGL2 Lgl_C PF08596.10 CBY15424.1 - 1.8e-06 26.9 0.0 1.2e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CBY15424.1 - 0.00018 21.8 0.1 0.007 16.6 0.1 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY15424.1 - 0.00023 21.9 8.2 0.0047 17.7 0.1 4.5 4 1 0 4 4 4 1 WD domain, G-beta repeat TSC22 PF01166.18 CBY15425.1 - 7.1e-05 23.0 4.0 0.0011 19.3 0.4 2.3 1 1 1 2 2 2 1 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 CBY15425.1 - 0.016 15.3 9.6 0.059 13.4 10.1 1.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Y_phosphatase3 PF13350.6 CBY15425.1 - 0.05 13.6 0.2 0.06 13.3 0.2 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family ING PF12998.7 CBY15425.1 - 0.23 12.1 5.4 0.36 11.5 4.9 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding YabA PF06156.13 CBY15425.1 - 0.27 11.9 6.9 7 7.3 7.0 2.2 1 1 0 1 1 1 0 Initiation control protein YabA DUF5320 PF17253.2 CBY15425.1 - 0.28 12.3 0.5 0.28 12.3 0.5 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) bZIP_1 PF00170.21 CBY15425.1 - 0.32 11.1 6.7 2.3 8.4 0.3 2.5 1 1 2 3 3 3 0 bZIP transcription factor GIT_CC PF16559.5 CBY15425.1 - 0.34 10.8 8.1 1.6 8.7 1.8 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_TATA_bd PF12325.8 CBY15425.1 - 0.79 10.0 11.9 0.089 13.0 6.3 1.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 CBY15425.1 - 2 8.9 13.0 7.8 7.0 3.3 2.2 1 1 1 2 2 2 0 Cell division protein ZapB FlxA PF14282.6 CBY15425.1 - 3.4 7.7 13.1 9.7 6.2 12.7 1.8 1 1 0 1 1 1 0 FlxA-like protein zf-RING_UBOX PF13445.6 CBY15427.1 - 0.023 14.7 1.7 0.049 13.7 1.7 1.7 1 1 0 1 1 1 0 RING-type zinc-finger Sulfatase PF00884.23 CBY15429.1 - 7.4e-47 160.2 0.0 1.4e-46 159.3 0.0 1.4 1 1 0 1 1 1 1 Sulfatase Zip PF02535.22 CBY15430.1 - 4.7e-34 118.1 12.7 1.8e-31 109.6 12.7 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter EF-hand_7 PF13499.6 CBY15431.1 - 0.00027 21.3 6.4 0.12 12.8 2.2 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY15431.1 - 0.0088 15.5 1.9 0.31 10.7 0.1 3.1 3 0 0 3 3 3 1 EF hand DUF4718 PF15842.5 CBY15431.1 - 0.076 12.8 0.3 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) EF-hand_6 PF13405.6 CBY15431.1 - 0.11 12.4 2.3 19 5.5 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain Transglut_prok PF09017.10 CBY15431.1 - 0.17 11.2 0.1 0.23 10.7 0.1 1.1 1 0 0 1 1 1 0 Microbial transglutaminase DnaJ PF00226.31 CBY15434.1 - 4.3e-06 26.8 4.9 2e-05 24.6 0.2 2.9 3 1 0 3 3 3 1 DnaJ domain RPT PF13446.6 CBY15434.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein IFP_35_N PF07334.13 CBY15434.1 - 0.035 14.2 3.6 0.036 14.1 2.0 1.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus UIM PF02809.20 CBY15434.1 - 0.096 12.6 2.3 1.1 9.3 0.8 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF3683 PF12447.8 CBY15434.1 - 0.12 12.5 1.2 0.15 12.2 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) DUF1943 PF09172.11 CBY15434.1 - 0.13 11.5 5.0 0.14 11.3 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF3080 PF11279.8 CBY15434.1 - 0.15 11.3 3.8 0.21 10.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) FlxA PF14282.6 CBY15434.1 - 0.46 10.5 8.7 0.54 10.3 8.1 1.5 1 1 0 1 1 1 0 FlxA-like protein AAA_23 PF13476.6 CBY15434.1 - 3.2 8.2 14.2 5.6 7.4 14.2 1.3 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 CBY15434.1 - 6.9 5.8 6.0 9 5.4 6.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Kelch_6 PF13964.6 CBY15436.1 - 4.8e-09 36.2 0.4 0.045 14.1 0.0 3.5 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CBY15436.1 - 7.4e-07 28.9 4.2 0.38 10.8 0.1 4.1 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CBY15436.1 - 1.7e-05 24.3 0.1 0.18 11.4 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY15436.1 - 0.00018 21.4 0.8 1.9 8.5 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY15436.1 - 0.0027 17.7 0.5 1.8 8.6 0.0 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY15436.1 - 0.11 12.8 1.0 49 4.4 0.0 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Activin_recp PF01064.23 CBY15437.1 - 2.5 9.2 22.0 0.049 14.7 7.1 2.6 1 1 0 2 2 2 0 Activin types I and II receptor domain LPMO_10 PF03067.15 CBY15439.1 - 4.8e-32 112.2 0.5 6e-32 111.9 0.5 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY15439.1 - 4.1e-10 39.7 1.5 4.1e-10 39.7 1.5 2.1 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Galactosyl_T PF01762.21 CBY15442.1 - 0.0064 16.3 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 Galactosyltransferase Aa_trans PF01490.18 CBY15444.1 - 8.6e-40 136.7 15.9 1.1e-39 136.3 15.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TatC PF00902.18 CBY15444.1 - 0.061 13.1 13.9 0.13 12.1 13.9 1.6 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Cdc13_OB2 PF18691.1 CBY15444.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Cell division control protein 13, OB2 domain Connexin PF00029.19 CBY15445.1 - 2.4e-36 125.7 6.2 3.2e-36 125.3 6.2 1.1 1 0 0 1 1 1 1 Connexin Halogen_Hydrol PF10112.9 CBY15445.1 - 0.11 12.5 0.1 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RabGAP-TBC PF00566.18 CBY15447.1 - 2.6e-29 102.4 3.4 2.5e-28 99.2 3.4 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain IL17R_fnIII_D2 PF16578.5 CBY15448.1 - 0.085 13.4 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 Interleukin 17 receptor D TPR_20 PF14561.6 CBY15449.1 - 0.026 14.9 0.2 0.026 14.9 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3987 PF13148.6 CBY15449.1 - 0.096 11.7 0.4 0.13 11.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) H2TH PF06831.14 CBY15451.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain PDZ PF00595.24 CBY15452.1 - 6.9e-11 42.4 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY15452.1 - 3e-05 23.8 0.0 6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY15452.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 PDZ domain YEATS PF03366.16 CBY15453.1 - 7.2e-22 77.2 0.1 9.4e-22 76.8 0.1 1.1 1 0 0 1 1 1 1 YEATS family MGAT2 PF05060.14 CBY15454.1 - 3.7e-80 269.6 1.5 5.4e-80 269.1 1.5 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) SSF PF00474.17 CBY15455.1 - 3.6e-12 45.9 7.7 3.6e-12 45.9 7.7 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2417 PF10329.9 CBY15455.1 - 0.015 14.7 0.9 0.015 14.7 0.9 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) UPF0547 PF10571.9 CBY15455.1 - 0.12 12.5 0.4 0.21 11.7 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF417 PF04224.12 CBY15455.1 - 3.1 7.3 8.1 0.24 11.0 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF417 NAD_binding_2 PF03446.15 CBY15456.1 - 3.9e-43 147.4 1.4 5.5e-43 146.9 1.4 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBY15456.1 - 4.9e-31 107.5 0.0 1.1e-30 106.3 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CBY15456.1 - 0.00034 21.1 0.0 0.00092 19.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CBY15456.1 - 0.00056 19.3 0.3 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4031 PF13223.6 CBY15456.1 - 0.15 12.3 0.1 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) DUF5442 PF17514.2 CBY15457.1 - 0.00051 20.2 1.7 0.83 9.9 0.9 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF5442) Bcl-2 PF00452.19 CBY15457.1 - 0.00069 20.2 0.2 0.004 17.8 0.1 2.2 1 1 1 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family DUF3320 PF11784.8 CBY15457.1 - 0.034 14.1 0.0 0.095 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Ku_PK_bind PF08785.11 CBY15457.1 - 0.04 14.1 0.8 2.1 8.5 0.3 2.4 2 0 0 2 2 2 0 Ku C terminal domain like DUF1090 PF06476.12 CBY15457.1 - 0.14 12.3 0.6 0.5 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) ORF6N PF10543.9 CBY15457.1 - 0.37 11.0 2.9 7 6.9 0.4 3.2 2 1 2 4 4 4 0 ORF6N domain RNase_J_C PF17770.1 CBY15457.1 - 0.63 11.1 2.3 9.4 7.4 0.2 3.1 2 1 0 3 3 3 0 Ribonuclease J C-terminal domain NAD_binding_2 PF03446.15 CBY15458.1 - 3.6e-25 89.0 0.0 4.3e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CBY15458.1 - 0.00026 21.5 0.0 0.00034 21.1 0.0 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CBY15458.1 - 0.0004 19.8 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CBY15458.1 - 0.071 13.0 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 CBY15458.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF4031 PF13223.6 CBY15458.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) DUF5442 PF17514.2 CBY15459.1 - 0.00042 20.5 1.6 0.75 10.0 0.9 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF5442) Bcl-2 PF00452.19 CBY15459.1 - 0.00061 20.4 0.2 0.0035 18.0 0.1 2.2 1 1 1 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family DUF3320 PF11784.8 CBY15459.1 - 0.032 14.2 0.0 0.09 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Ku_PK_bind PF08785.11 CBY15459.1 - 0.035 14.3 0.8 2 8.6 0.3 2.4 2 0 0 2 2 2 0 Ku C terminal domain like DUF1090 PF06476.12 CBY15459.1 - 0.12 12.5 0.6 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) ORF6N PF10543.9 CBY15459.1 - 0.28 11.4 2.8 6.6 7.0 0.4 3.2 2 1 2 4 4 4 0 ORF6N domain RNase_J_C PF17770.1 CBY15459.1 - 0.65 11.1 2.4 8.9 7.4 0.2 3.1 2 1 0 3 3 3 0 Ribonuclease J C-terminal domain SPT6_acidic PF14632.6 CBY15460.1 - 8.5e-10 39.1 21.4 8.5e-10 39.1 21.4 7.5 1 1 4 5 5 5 1 Acidic N-terminal SPT6 Glycos_transf_2 PF00535.26 CBY15461.1 - 2e-16 60.2 0.0 4.3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Osmo_CC PF08946.10 CBY15461.1 - 0.19 12.0 1.7 0.41 10.9 1.7 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Forkhead PF00250.18 CBY15462.1 - 2.8e-12 46.7 0.1 7.8e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain Pellino PF04710.14 CBY15463.1 - 6.7e-147 489.5 0.1 8.1e-147 489.2 0.1 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 CBY15463.1 - 0.0035 17.2 6.2 0.44 10.4 1.1 3.3 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY15463.1 - 0.096 13.0 6.4 1.2 9.5 1.0 3.0 2 0 0 2 2 2 0 Ring finger domain ORC2 PF04084.14 CBY15463.1 - 0.14 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 zf-C3HC4_3 PF13920.6 CBY15463.1 - 0.57 10.1 11.8 8.7 6.3 4.0 4.0 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 CBY15463.1 - 2.4 8.5 9.1 2.8 8.3 0.5 3.5 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding RRM_1 PF00076.22 CBY15464.1 - 1.9e-12 46.8 0.1 2.6e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY15464.1 - 0.027 14.3 0.0 0.064 13.1 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_8 PF11835.8 CBY15464.1 - 0.047 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain RRM_5 PF13893.6 CBY15464.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1_POZ PF03931.15 CBY15465.1 - 4e-21 75.0 0.7 5.9e-21 74.4 0.7 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 CBY15465.1 - 2e-08 34.2 0.0 4.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain RRM_1 PF00076.22 CBY15469.1 - 6.4e-41 138.0 0.5 2.1e-17 62.7 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY15469.1 - 0.0095 16.0 0.1 0.22 11.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif zf-C4 PF00105.18 CBY15470.1 - 1.3e-31 108.9 18.3 2.3e-31 108.0 18.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY15470.1 - 1.8e-13 50.6 0.6 7.6e-13 48.5 0.1 2.2 2 1 1 3 3 3 1 Ligand-binding domain of nuclear hormone receptor Ammonium_transp PF00909.21 CBY15471.1 - 1.8e-80 270.6 17.7 2.3e-80 270.3 17.7 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family WD40 PF00400.32 CBY15472.1 - 0.0033 18.2 0.0 0.075 13.9 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY15472.1 - 0.093 13.0 0.0 8.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Corona_6B_7B PF03262.13 CBY15472.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein KIX_2 PF16987.5 CBY15473.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 KIX domain Hepatitis_core PF00906.20 CBY15474.1 - 0.0056 16.3 0.3 0.011 15.4 0.1 1.5 2 0 0 2 2 2 1 Hepatitis core antigen Ectoine_synth PF06339.12 CBY15475.1 - 0.11 12.8 0.5 0.26 11.5 0.4 1.6 1 1 0 1 1 1 0 Ectoine synthase DUF4407 PF14362.6 CBY15475.1 - 4.2 6.7 7.8 1.5 8.1 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Tmem26 PF09772.9 CBY15476.1 - 3.1e-19 69.4 0.2 4.1e-19 69.0 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 26 Pkinase_Tyr PF07714.17 CBY15477.1 - 5.9e-57 192.9 0.0 1.1e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY15477.1 - 5.3e-34 117.8 0.0 1.1e-33 116.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CBY15477.1 - 0.0047 15.9 0.3 0.0047 15.9 0.3 2.6 2 1 2 4 4 4 1 Haspin like kinase domain wnt PF00110.19 CBY15479.1 - 1.8e-43 149.3 12.2 4.2e-30 105.4 11.5 2.1 1 1 1 2 2 2 2 wnt family ThiF PF00899.21 CBY15481.1 - 1.1e-61 208.3 0.2 1.6e-61 207.8 0.2 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CBY15481.1 - 4.7e-09 36.7 0.0 1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain ApbA PF02558.16 CBY15481.1 - 0.055 13.1 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Tubulin_2 PF13809.6 CBY15481.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Sacchrp_dh_NADP PF03435.18 CBY15481.1 - 0.89 9.8 2.6 10 6.4 2.6 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LIN52 PF10044.9 CBY15482.1 - 8.1e-20 71.3 0.2 1e-19 71.0 0.2 1.1 1 0 0 1 1 1 1 Retinal tissue protein PS_Dcarbxylase PF02666.15 CBY15483.1 - 2e-07 30.7 0.0 2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DNA_pol3_finger PF17657.1 CBY15483.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain Calsequestrin PF01216.17 CBY15484.1 - 2.6e-11 43.2 0.0 2.7e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Calsequestrin ATP-grasp_6 PF18419.1 CBY15484.1 - 0.18 11.5 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp-like domain Armet PF10208.9 CBY15485.1 - 1.7e-17 63.7 1.6 1.9e-17 63.5 1.6 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding DUF1394 PF07159.12 CBY15485.1 - 0.061 12.6 0.0 0.066 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) Globin PF00042.22 CBY15485.1 - 0.11 13.1 0.0 0.12 13.0 0.0 1.1 1 0 0 1 1 1 0 Globin BTB PF00651.31 CBY15486.1 - 2.5e-06 27.7 0.0 4.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CTD_bind PF04818.13 CBY15486.1 - 8.1e-06 26.6 0.1 1.6e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DnaG_DnaB_bind PF08278.11 CBY15489.1 - 0.13 12.9 0.6 0.3 11.7 0.6 1.7 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding RVT_1 PF00078.27 CBY15491.1 - 5.5e-10 39.1 0.0 1.4e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Baculo_F PF12259.8 CBY15496.1 - 0.00048 18.8 1.5 0.0006 18.5 1.5 1.0 1 0 0 1 1 1 1 Baculovirus F protein Methyltransf_22 PF13383.6 CBY15496.1 - 0.0064 16.1 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NB PF04159.13 CBY15496.1 - 0.044 13.8 0.4 0.073 13.1 0.4 1.3 1 0 0 1 1 1 0 NB glycoprotein DUF4519 PF15012.6 CBY15496.1 - 0.39 10.9 2.1 0.71 10.1 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) G-patch_2 PF12656.7 CBY15497.1 - 2.1e-21 75.7 0.4 7e-21 74.1 0.4 2.0 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 CBY15497.1 - 7.1e-05 22.6 1.6 0.0025 17.7 0.5 2.8 2 0 0 2 2 2 1 KOW motif G-patch PF01585.23 CBY15497.1 - 0.00033 20.5 4.6 0.00083 19.2 4.6 1.7 1 0 0 1 1 1 1 G-patch domain DUF3885 PF13021.6 CBY15497.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) EF-hand_7 PF13499.6 CBY15498.1 - 6.1e-08 33.0 1.9 2.6e-07 31.0 1.8 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY15498.1 - 2.1e-05 24.1 1.2 0.00029 20.5 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain RST PF12174.8 CBY15498.1 - 4.8e-05 23.2 1.6 9.6e-05 22.2 0.8 1.9 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_1 PF00036.32 CBY15498.1 - 6.3e-05 22.2 1.5 0.00041 19.7 0.1 2.9 3 0 0 3 3 3 1 EF hand Dockerin_1 PF00404.18 CBY15498.1 - 0.0041 17.3 0.0 0.0091 16.2 0.0 1.6 1 0 0 1 1 1 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 CBY15498.1 - 0.0044 17.3 0.4 0.3 11.4 0.1 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 CBY15498.1 - 0.0098 15.4 0.1 0.023 14.2 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CBY15498.1 - 0.021 14.6 0.8 4.7 7.1 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_4 PF12763.7 CBY15498.1 - 0.054 13.5 0.3 0.13 12.2 0.1 1.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CBY15498.1 - 0.091 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Spt5-NGN PF03439.13 CBY15499.1 - 9.5e-23 79.9 0.1 1.7e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CBY15499.1 - 4.3e-22 77.3 23.7 6.1e-07 29.2 5.2 7.6 7 0 0 7 7 7 5 KOW motif CTD PF12815.7 CBY15499.1 - 0.00015 22.3 27.0 0.00015 22.3 27.0 3.9 2 1 1 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 CBY15499.1 - 0.00021 21.5 2.8 0.012 15.9 0.1 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF3912) Myosin_N PF02736.19 CBY15499.1 - 0.01 15.7 0.9 0.23 11.3 0.0 3.1 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DLH PF01738.18 CBY15499.1 - 0.07 12.7 0.4 0.11 12.0 0.4 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family zf-RING-like PF08746.11 CBY15499.1 - 0.15 12.4 0.2 0.33 11.3 0.2 1.4 1 0 0 1 1 1 0 RING-like domain Thioredoxin PF00085.20 CBY15500.1 - 3.5e-11 43.0 0.0 6.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CBY15500.1 - 0.0062 16.4 0.1 0.033 14.1 0.1 1.9 1 1 1 2 2 2 1 AhpC/TSA family TraF PF13728.6 CBY15500.1 - 0.075 12.8 0.5 0.78 9.5 0.2 2.2 1 1 1 2 2 2 0 F plasmid transfer operon protein DUF768 PF05589.11 CBY15501.1 - 0.013 15.5 0.6 0.067 13.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF768) IBN_N PF03810.19 CBY15505.1 - 0.27 11.2 4.2 9.7 6.2 0.0 3.2 3 1 1 4 4 4 0 Importin-beta N-terminal domain PSCyt3 PF07627.11 CBY15506.1 - 0.98 9.7 6.2 5.1 7.4 0.0 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1588) ABC_tran PF00005.27 CBY15508.1 - 3.6e-12 47.0 0.2 4.2e-12 46.7 0.2 1.0 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY15508.1 - 0.0016 18.3 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CBY15508.1 - 0.0039 17.7 0.1 0.0051 17.4 0.1 1.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CBY15508.1 - 0.014 15.1 0.1 0.023 14.4 0.1 1.3 1 1 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.6 CBY15508.1 - 0.027 14.2 0.3 0.05 13.3 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY15508.1 - 0.027 15.0 3.1 0.22 12.0 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 CBY15508.1 - 0.05 13.9 0.1 0.089 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY15508.1 - 0.058 13.8 0.0 0.064 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 CBY15508.1 - 0.071 13.5 0.1 0.11 12.9 0.1 1.4 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 CBY15508.1 - 0.073 13.3 0.2 0.22 11.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CBY15508.1 - 0.1 12.5 0.2 0.18 11.7 0.2 1.5 1 1 0 1 1 1 0 RsgA GTPase RRM_1 PF00076.22 CBY15509.1 - 2.6e-09 36.8 0.0 4.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med9 PF07544.13 CBY15509.1 - 0.58 10.3 0.0 0.58 10.3 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 COPI_C PF06957.11 CBY15510.1 - 4.7e-165 549.2 0.0 5.5e-165 549.0 0.0 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 CBY15510.1 - 3.6e-09 36.2 0.0 5.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region zf-B_box PF00643.24 CBY15512.1 - 1.6e-08 34.5 7.0 2.9e-08 33.7 7.0 1.4 1 0 0 1 1 1 1 B-box zinc finger FYVE PF01363.21 CBY15512.1 - 0.0012 19.0 0.1 0.0022 18.1 0.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger ALIX_LYPXL_bnd PF13949.6 CBY15512.1 - 0.0051 16.1 5.0 0.0067 15.8 5.0 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Fez1 PF06818.15 CBY15512.1 - 0.069 13.6 5.1 0.097 13.1 5.1 1.3 1 0 0 1 1 1 0 Fez1 UPF0184 PF03670.13 CBY15512.1 - 0.16 12.4 8.0 0.051 14.0 4.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) DUF5320 PF17253.2 CBY15512.1 - 0.37 11.9 1.2 0.78 10.8 1.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF3232 PF11554.8 CBY15512.1 - 0.41 11.0 4.6 0.89 9.9 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3232) DUF1043 PF06295.12 CBY15512.1 - 0.59 10.1 3.2 0.44 10.6 0.7 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) CCDC-167 PF15188.6 CBY15512.1 - 0.88 10.0 7.4 2.1 8.7 7.4 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 MFS_1 PF07690.16 CBY15514.1 - 3e-13 49.4 11.5 4.1e-13 49.0 11.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PspB PF06667.12 CBY15514.1 - 0.34 11.0 0.1 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 Phage shock protein B KRTAP PF11759.8 CBY15514.1 - 8.9 6.9 7.3 7.6 7.2 0.7 2.3 2 0 0 2 2 2 0 Keratin-associated matrix MFS_4 PF06779.14 CBY15515.1 - 0.00028 20.3 0.7 0.00035 20.0 0.7 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ThiJ_like PF17124.5 CBY15517.1 - 0.084 12.5 0.8 1.2 8.8 0.0 2.1 1 1 1 2 2 2 0 ThiJ/PfpI family-like Homeodomain PF00046.29 CBY15518.1 - 2e-10 40.4 0.9 2.9e-10 39.8 0.9 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY15518.1 - 0.035 14.0 0.4 0.057 13.3 0.4 1.3 1 0 0 1 1 1 0 Homeobox KN domain Trypan_PARP PF05887.11 CBY15520.1 - 3.9 7.5 5.5 10 6.1 5.5 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trypsin PF00089.26 CBY15521.1 - 3e-51 174.3 0.1 6.8e-51 173.2 0.1 1.5 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 CBY15521.1 - 1.4e-30 105.4 20.6 1.4e-18 67.0 8.2 2.5 2 0 0 2 2 2 2 Kringle domain Trypsin_2 PF13365.6 CBY15521.1 - 0.0084 17.0 0.0 0.017 16.0 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Toxin_5 PF05294.13 CBY15521.1 - 0.73 10.3 4.7 26 5.3 0.4 3.4 2 0 0 2 2 2 0 Scorpion short toxin fn3 PF00041.21 CBY15522.1 - 0.00017 21.8 0.4 0.0025 18.1 0.1 2.9 3 0 0 3 3 3 1 Fibronectin type III domain Stealth_CR2 PF11380.8 CBY15522.1 - 0.0072 16.5 0.0 0.024 14.8 0.0 1.9 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 ABC2_membrane_2 PF12679.7 CBY15522.1 - 0.12 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein HECT PF00632.25 CBY15525.1 - 4e-85 286.0 0.4 7.2e-85 285.1 0.4 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2201_N PF13203.6 CBY15525.1 - 0.044 13.4 1.5 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain Meth_synt_2 PF01717.18 CBY15525.1 - 0.066 12.5 0.0 0.31 10.2 0.0 1.9 2 0 0 2 2 2 0 Cobalamin-independent synthase, Catalytic domain SGS PF05002.15 CBY15525.1 - 0.13 12.4 2.0 7.5 6.7 0.1 3.1 2 0 0 2 2 2 0 SGS domain RasGEF_N_2 PF14663.6 CBY15526.1 - 3.4e-08 33.9 3.5 1e-07 32.3 0.2 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 CBY15526.1 - 3.6e-07 30.3 0.2 1.4e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 Sigma70_ner PF04546.13 CBY15526.1 - 0.031 14.1 0.7 0.55 10.1 0.2 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region RICTOR_N PF14664.6 CBY15527.1 - 7e-29 101.0 3.0 8.8e-29 100.6 3.0 1.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term DUF3896 PF13035.6 CBY15528.1 - 0.04 14.1 0.7 8.8 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) Kelch_2 PF07646.15 CBY15529.1 - 0.00047 20.0 0.8 3.1 7.9 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 CBY15529.1 - 0.018 15.0 0.8 2.5 8.2 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY15529.1 - 0.033 14.5 0.4 2.2 8.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif DUF1905 PF08922.11 CBY15529.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) Kelch_5 PF13854.6 CBY15529.1 - 0.45 10.6 3.2 3.7 7.6 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Dicty_REP PF05086.12 CBY15529.1 - 0.46 8.4 3.2 0.57 8.1 3.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein KCT2 PF17818.1 CBY15529.1 - 1.3 9.1 3.8 2.1 8.4 3.8 1.3 1 0 0 1 1 1 0 Keratinocyte-associated gene product Pkinase PF00069.25 CBY15530.1 - 1.3e-09 37.9 1.2 1.9e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15530.1 - 4.1e-05 23.0 0.0 9e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HisK_sensor PF18698.1 CBY15530.1 - 0.31 11.4 1.8 0.32 11.4 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase sensor domain DUF4200 PF13863.6 CBY15532.1 - 3e-16 59.9 4.6 3e-16 59.9 4.6 4.1 5 0 0 5 5 5 2 Domain of unknown function (DUF4200) TBCA PF02970.16 CBY15532.1 - 0.00082 19.7 1.7 0.00082 19.7 1.7 3.9 3 2 1 4 4 4 1 Tubulin binding cofactor A Syntaxin-6_N PF09177.11 CBY15532.1 - 0.022 15.3 0.3 0.022 15.3 0.3 3.9 3 1 0 4 4 4 0 Syntaxin 6, N-terminal APG6_N PF17675.1 CBY15532.1 - 0.089 13.3 0.3 0.089 13.3 0.3 4.0 3 1 0 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 CBY15532.1 - 0.16 12.0 5.8 5.2 7.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1043 PF06295.12 CBY15532.1 - 4.4 7.3 9.2 0.54 10.3 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) YvrJ PF12841.7 CBY15532.1 - 7.5 6.2 6.1 30 4.3 0.2 3.3 3 1 0 3 3 3 0 YvrJ protein family zf-MYND PF01753.18 CBY15533.1 - 0.0014 18.7 16.3 0.0034 17.4 16.3 1.7 1 0 0 1 1 1 1 MYND finger Ferrochelatase PF00762.19 CBY15534.1 - 1.9e-104 349.2 0.0 2.2e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase FERM_N PF09379.10 CBY15536.1 - 3.4e-05 23.7 0.0 6.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain Tubulin PF00091.25 CBY15537.1 - 1.1e-67 228.1 0.0 1.8e-67 227.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY15537.1 - 2.5e-42 144.0 0.1 4.1e-42 143.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY15537.1 - 9.8e-06 25.9 0.0 2.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBY15537.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBY15537.1 - 0.034 13.3 0.0 0.089 12.0 0.0 1.6 2 0 0 2 2 2 0 Tubulin like TrmK PF04816.12 CBY15537.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Spc7 PF08317.11 CBY15538.1 - 0.0011 17.9 1.5 0.0011 17.9 1.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF684 PF05075.14 CBY15538.1 - 0.0029 16.7 0.4 0.0034 16.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF684) Fmp27_WPPW PF10359.9 CBY15538.1 - 0.0076 15.2 1.4 0.0083 15.0 1.4 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF16 PF01519.16 CBY15538.1 - 0.0088 16.5 1.2 0.011 16.2 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF16 Paralemmin PF03285.15 CBY15538.1 - 0.0099 15.5 0.9 0.011 15.4 0.9 1.0 1 0 0 1 1 1 1 Paralemmin DUF3474 PF11960.8 CBY15538.1 - 0.023 14.9 0.1 0.026 14.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Muted PF14942.6 CBY15538.1 - 0.033 14.5 6.2 0.041 14.2 6.2 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF4140 PF13600.6 CBY15538.1 - 0.046 14.2 1.8 0.046 14.2 1.8 1.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TcpS PF17456.2 CBY15538.1 - 0.059 13.4 2.1 0.077 13.0 2.1 1.2 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S FlaC_arch PF05377.11 CBY15538.1 - 0.087 13.2 2.3 0.19 12.2 0.8 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF3847 PF12958.7 CBY15538.1 - 0.1 12.7 5.0 0.17 12.0 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) XhlA PF10779.9 CBY15538.1 - 0.1 12.8 2.0 0.16 12.2 2.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Rotamase_2 PF13145.6 CBY15538.1 - 0.13 13.1 4.9 0.16 12.8 4.9 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain VPS38 PF17649.1 CBY15538.1 - 0.17 10.8 2.9 0.19 10.6 2.9 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 OmpH PF03938.14 CBY15538.1 - 0.25 11.7 7.8 0.31 11.4 7.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3482 PF11981.8 CBY15538.1 - 0.26 10.7 2.0 0.29 10.5 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Nup88 PF10168.9 CBY15538.1 - 0.29 8.9 2.9 0.27 9.0 2.9 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF1910 PF08928.10 CBY15538.1 - 0.37 10.8 5.1 0.55 10.2 5.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) DivIC PF04977.15 CBY15538.1 - 0.7 9.7 8.8 1.7 8.5 8.8 1.7 1 1 0 1 1 1 0 Septum formation initiator CLP1_P PF16575.5 CBY15539.1 - 2.2e-25 89.6 0.0 3.6e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop HA2 PF04408.23 CBY15540.1 - 2.3e-23 82.5 0.1 4.4e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBY15540.1 - 3.5e-19 68.9 0.0 7.8e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBY15540.1 - 6.2e-05 22.8 0.1 0.00012 21.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY15540.1 - 0.0087 16.3 0.1 0.031 14.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY15540.1 - 0.08 13.3 0.1 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 CBY15540.1 - 0.098 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 CBY15540.1 - 0.098 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CBY15540.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain BRCT PF00533.26 CBY15541.1 - 7e-17 61.6 0.0 2.8e-16 59.6 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CBY15541.1 - 9.2e-06 25.5 0.2 3.2e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain AAA PF00004.29 CBY15541.1 - 3.8e-05 24.1 0.7 7.9e-05 23.1 0.2 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT_2 PF16589.5 CBY15541.1 - 0.00049 20.5 0.1 0.0015 18.9 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RuvB_N PF05496.12 CBY15541.1 - 0.00083 19.1 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CBY15541.1 - 0.0022 17.9 0.6 0.098 12.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CBY15541.1 - 0.0045 17.4 0.1 0.01 16.2 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 CBY15541.1 - 0.072 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 CBY15541.1 - 0.085 13.0 0.5 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CBY15541.1 - 0.091 12.8 0.1 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY15541.1 - 0.1 12.9 0.2 0.37 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 CBY15542.1 - 0.25 9.9 21.4 0.27 9.8 21.4 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CBY15542.1 - 1.6 5.7 31.8 2.1 5.3 31.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Galactosyl_T PF01762.21 CBY15544.1 - 1e-15 58.1 0.2 1.3e-15 57.8 0.2 1.1 1 0 0 1 1 1 1 Galactosyltransferase VWA PF00092.28 CBY15545.1 - 1.4e-20 74.2 0.1 2.5e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY15545.1 - 1.2e-09 38.7 0.0 2.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 CBY15545.1 - 0.00029 21.1 6.1 0.00051 20.3 6.1 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site VWA_3 PF13768.6 CBY15545.1 - 0.0023 17.9 0.1 0.0084 16.1 0.1 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain TIL PF01826.17 CBY15545.1 - 0.023 14.9 4.7 0.045 14.0 4.7 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain VWA_CoxE PF05762.14 CBY15545.1 - 0.13 11.6 0.1 0.81 9.0 0.1 2.0 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Osmo_CC PF08946.10 CBY15545.1 - 0.81 10.0 3.6 5.6 7.3 0.2 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil AMPK1_CBM PF16561.5 CBY15546.1 - 1.3e-20 73.4 0.0 2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 CBY15546.1 - 0.015 15.9 0.0 0.031 14.9 0.0 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) RT_RNaseH PF17917.1 CBY15548.1 - 2.8e-27 95.0 0.1 5.3e-27 94.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY15548.1 - 7.2e-22 77.3 0.0 1.8e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY15548.1 - 4.6e-17 62.3 0.0 1.3e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CBY15548.1 - 5.9e-14 52.1 0.0 1.5e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY15548.1 - 5.3e-08 32.9 0.0 1.4e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS240 PF13610.6 CBY15548.1 - 0.00049 20.3 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 DDE domain RabGAP-TBC PF00566.18 CBY15549.1 - 3.4e-48 164.2 0.3 3.4e-48 164.2 0.3 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain PID PF00640.23 CBY15549.1 - 0.022 14.8 2.5 6.2 6.9 0.0 3.0 2 1 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) SIN1_PH PF16979.5 CBY15549.1 - 0.059 13.7 0.4 17 5.7 0.1 2.9 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology WBP-1 PF11669.8 CBY15552.1 - 9.4e-20 71.2 3.1 1.5e-19 70.6 3.1 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 UQ_con PF00179.26 CBY15553.1 - 1.6e-48 163.9 0.0 1.8e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY15553.1 - 0.15 12.4 0.3 0.21 11.9 0.3 1.3 1 1 0 1 1 1 0 RWD domain Trypsin PF00089.26 CBY15554.1 - 1.9e-105 351.6 8.2 2.3e-52 178.0 0.1 2.2 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CBY15554.1 - 1.4e-09 39.0 0.5 0.0012 19.8 0.0 2.8 3 0 0 3 3 3 2 Trypsin-like peptidase domain EF-hand_7 PF13499.6 CBY15555.1 - 8.9e-07 29.3 0.1 1.8e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY15555.1 - 1.1e-06 28.4 0.2 1.9e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY15555.1 - 2.6e-06 26.6 1.4 1.5e-05 24.2 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY15555.1 - 5.9e-06 25.8 0.3 3.1e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBY15555.1 - 0.00056 19.3 0.8 0.0015 17.9 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 CBY15555.1 - 0.019 14.8 0.2 0.15 12.0 0.2 2.1 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 CBY15555.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DBD_Tnp_Mut PF03108.15 CBY15556.1 - 0.0091 16.0 0.6 0.0091 16.0 0.6 2.3 3 0 0 3 3 3 1 MuDR family transposase Zona_pellucida PF00100.23 CBY15557.1 - 4.5e-37 128.3 1.3 8.8e-37 127.3 1.3 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain wnt PF00110.19 CBY15558.1 - 1.3e-40 139.9 15.0 3.9e-29 102.2 10.1 2.0 1 1 1 2 2 2 2 wnt family Histone_H2A_C PF16211.5 CBY15559.1 - 3.4e-17 61.9 2.1 7.8e-17 60.7 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY15559.1 - 1.6e-16 60.9 0.0 2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY15559.1 - 7.2e-06 26.2 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY15560.1 - 5.4e-18 65.6 0.1 6.6e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY15560.1 - 0.00013 22.1 0.1 0.0003 21.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY15560.1 - 0.0034 17.8 0.4 0.0099 16.4 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY15560.1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 YscO-like protein Trypsin PF00089.26 CBY15561.1 - 8.3e-54 182.7 1.1 1.1e-53 182.3 1.1 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY15561.1 - 0.019 15.4 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Ig_3 PF13927.6 CBY15562.1 - 3.8e-17 62.6 0.5 4e-11 43.3 0.0 2.7 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CBY15562.1 - 7.4e-11 42.0 0.6 7.4e-06 25.9 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 CBY15562.1 - 2.4e-07 30.9 0.5 0.001 19.2 0.0 3.2 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 CBY15562.1 - 4.1e-07 30.2 0.3 0.00016 21.9 0.0 2.8 2 2 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CBY15562.1 - 0.00041 20.5 1.0 0.11 12.7 0.0 3.5 2 2 1 3 3 3 1 Immunoglobulin domain PspB PF06667.12 CBY15563.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 1 0 1 1 1 0 Phage shock protein B FXa_inhibition PF14670.6 CBY15564.1 - 0.00012 22.3 3.2 0.00018 21.7 3.2 1.2 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 CBY15564.1 - 0.0015 19.0 0.0 1.8 9.1 0.1 2.3 2 0 0 2 2 2 2 Low-density lipoprotein receptor repeat class B DUF4366 PF14283.6 CBY15565.1 - 0.057 13.5 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Zona_pellucida PF00100.23 CBY15566.1 - 5.1e-13 49.4 0.0 6.3e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3785 PF12653.7 CBY15567.1 - 0.0025 18.0 0.3 0.0027 17.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3785) M20_dimer PF07687.14 CBY15569.1 - 0.064 13.2 0.1 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Peptidase dimerisation domain Na_H_Exchanger PF00999.21 CBY15570.1 - 8.9e-68 228.8 37.4 1.1e-67 228.4 37.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-RRN7 PF11781.8 CBY15572.1 - 0.027 14.2 1.7 0.04 13.6 0.9 1.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Auto_anti-p27 PF06677.12 CBY15572.1 - 0.2 11.8 1.2 0.38 10.9 1.2 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MFS_1 PF07690.16 CBY15575.1 - 0.0002 20.4 3.2 0.00045 19.3 2.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY15575.1 - 0.00032 19.7 0.2 0.00067 18.6 0.2 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 CBY15575.1 - 0.017 14.2 0.1 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 Nucleoside H+ symporter Sugar_tr PF00083.24 CBY15577.1 - 4.5e-18 65.4 6.5 4.9e-18 65.2 6.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY15577.1 - 0.0053 15.7 25.6 0.02 13.8 25.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_VLTF3 PF04947.14 CBY15577.1 - 0.087 12.5 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Carn_acyltransf PF00755.20 CBY15579.1 - 1.4e-78 265.0 0.0 1.6e-78 264.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sulfotransfer_4 PF17784.1 CBY15580.1 - 4.7e-45 154.1 0.7 6e-45 153.7 0.7 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY15580.1 - 0.0028 18.1 0.0 0.0063 16.9 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family zf-MYND PF01753.18 CBY15581.1 - 0.0044 17.1 19.0 0.0081 16.2 19.0 1.4 1 0 0 1 1 1 1 MYND finger Sulfatase PF00884.23 CBY15582.1 - 1.4e-54 185.6 0.0 1.9e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase EF-hand_1 PF00036.32 CBY15583.1 - 1.4e-06 27.4 0.0 0.015 14.8 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY15583.1 - 0.00016 21.3 0.0 0.55 10.3 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY15583.1 - 0.00018 20.9 0.1 3 7.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY15583.1 - 0.0083 16.0 0.0 0.031 14.1 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair Astro_capsid_p2 PF16580.5 CBY15583.1 - 0.056 12.9 1.5 0.29 10.5 0.1 2.1 1 1 1 2 2 2 0 C-terminal tail of astrovirus capsid projection or spike EF-hand_4 PF12763.7 CBY15583.1 - 0.072 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CBY15583.1 - 0.17 12.3 0.0 1.4 9.5 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain pair Pkinase PF00069.25 CBY15587.1 - 4e-26 92.0 0.0 4.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15587.1 - 1.2e-11 44.4 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY15587.1 - 2e-06 26.9 0.1 2.2e-06 26.7 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY15587.1 - 0.014 14.4 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBY15587.1 - 0.041 13.8 0.0 0.077 12.9 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY15587.1 - 0.065 12.5 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CBY15587.1 - 0.19 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_59 PF02057.15 CBY15588.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 DUF588 PF04535.12 CBY15589.1 - 0.0051 16.6 1.3 0.0082 15.9 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF588) Tetraspanin PF00335.20 CBY15589.1 - 1.5 8.5 6.6 0.48 10.1 4.3 1.4 1 1 0 1 1 1 0 Tetraspanin family Lectin_C PF00059.21 CBY15590.1 - 2.5e-17 63.5 0.2 6e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 Lectin C-type domain Phospholip_A2_1 PF00068.19 CBY15591.1 - 1.3e-15 57.8 4.4 3e-15 56.7 4.4 1.5 1 0 0 1 1 1 1 Phospholipase A2 EB PF01683.18 CBY15591.1 - 0.35 11.2 5.9 0.52 10.6 0.7 2.6 2 0 0 2 2 2 0 EB module Synaptobrevin PF00957.21 CBY15592.1 - 0.0016 18.2 4.2 0.004 16.9 4.2 1.7 1 0 0 1 1 1 1 Synaptobrevin Tmemb_9 PF05434.11 CBY15592.1 - 0.002 18.0 2.8 0.11 12.4 0.6 2.5 3 0 0 3 3 3 2 TMEM9 DUF3976 PF13121.6 CBY15592.1 - 0.032 14.4 3.3 0.05 13.7 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) Aa_trans PF01490.18 CBY15593.1 - 1.9e-75 254.1 22.8 2.2e-75 253.9 22.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MARVEL PF01284.23 CBY15593.1 - 0.01 15.9 1.6 0.01 15.9 1.6 3.5 2 2 2 4 4 4 0 Membrane-associating domain Phospholamban PF04272.14 CBY15593.1 - 0.74 9.3 7.0 0.37 10.3 0.2 3.3 3 0 0 3 3 3 0 Phospholamban hEGF PF12661.7 CBY15594.1 - 3.5e-12 46.5 16.2 7.1e-07 29.6 4.1 2.8 2 0 0 2 2 2 2 Human growth factor-like EGF EGF PF00008.27 CBY15594.1 - 6.8e-12 45.5 17.3 6.8e-08 32.7 4.1 2.5 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 CBY15594.1 - 5.9e-05 23.3 23.8 0.0007 19.9 8.3 2.3 2 0 0 2 2 2 2 EGF-like domain EB PF01683.18 CBY15594.1 - 0.0093 16.2 21.5 0.06 13.6 9.4 2.6 1 1 1 2 2 2 1 EB module cEGF PF12662.7 CBY15594.1 - 0.046 13.7 0.2 0.046 13.7 0.2 4.4 3 2 0 3 3 3 0 Complement Clr-like EGF-like Laminin_EGF PF00053.24 CBY15594.1 - 2.5 8.3 21.1 2 8.6 5.8 2.3 1 1 1 2 2 2 0 Laminin EGF domain bZIP_1 PF00170.21 CBY15595.1 - 0.052 13.6 0.4 0.052 13.6 0.4 3.2 1 1 1 2 2 2 0 bZIP transcription factor BRCT_2 PF16589.5 CBY15596.1 - 8.8e-12 45.3 0.0 1.5e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CBY15596.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Chlam_PMP PF02415.17 CBY15598.1 - 0.038 14.5 0.0 0.19 12.3 0.0 2.3 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Gal_Lectin PF02140.18 CBY15599.1 - 4.3e-16 59.1 1.3 4.4e-16 59.1 0.1 1.6 2 0 0 2 2 2 1 Galactose binding lectin domain Kelch_2 PF07646.15 CBY15601.1 - 0.0021 17.9 0.3 0.55 10.3 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY15601.1 - 0.1 12.9 1.4 1.1 9.6 0.1 2.9 3 0 0 3 3 3 0 Kelch motif T4_deiodinase PF00837.17 CBY15603.1 - 2.8e-29 102.1 0.0 3.1e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Cation_ATPase_C PF00689.21 CBY15605.1 - 2e-40 138.5 4.6 2.3e-40 138.3 4.6 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus EGF_2 PF07974.13 CBY15607.1 - 4e-18 65.5 171.1 7.6e-05 23.0 11.6 11.0 10 1 0 10 10 10 9 EGF-like domain EGF PF00008.27 CBY15607.1 - 2.2e-14 53.4 135.7 0.00057 20.1 12.4 11.4 10 1 0 10 10 10 7 EGF-like domain EGF_CA PF07645.15 CBY15607.1 - 8.6e-06 25.9 30.2 0.00017 21.7 4.9 11.5 7 2 4 11 11 11 3 Calcium-binding EGF domain hEGF PF12661.7 CBY15607.1 - 1.2e-05 25.7 130.6 0.0003 21.3 3.5 13.5 12 3 2 14 14 14 9 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 CBY15607.1 - 0.0054 17.0 13.2 0.012 16.0 2.7 10.6 8 1 0 8 8 8 3 Pvs28 EGF domain Collectrin PF16959.5 CBY15607.1 - 0.027 14.2 0.1 0.041 13.7 0.1 1.2 1 0 0 1 1 1 0 Renal amino acid transporter SNF2_N PF00176.23 CBY15608.1 - 6.1e-40 137.0 0.4 6.1e-40 137.0 0.4 2.3 2 1 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 CBY15608.1 - 9.2e-10 38.8 0.0 9.2e-10 38.8 0.0 4.2 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit 6PF2K PF01591.18 CBY15608.1 - 0.0011 18.3 0.2 0.0042 16.4 0.0 2.1 2 0 0 2 2 2 1 6-phosphofructo-2-kinase APS_kinase PF01583.20 CBY15608.1 - 0.0078 16.1 0.0 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 CBY15608.1 - 0.056 14.0 0.0 0.056 14.0 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.6 CBY15608.1 - 0.074 13.1 0.2 0.58 10.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 CBY15608.1 - 0.11 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Torsin KAP_NTPase PF07693.14 CBY15608.1 - 0.82 8.9 0.0 0.82 8.9 0.0 3.1 3 0 0 3 3 3 0 KAP family P-loop domain Acyl_transf_1 PF00698.21 CBY15609.1 - 0.11 12.0 0.3 1 8.8 0.1 2.0 1 1 1 2 2 2 0 Acyl transferase domain Pterin_4a PF01329.19 CBY15609.1 - 0.15 12.3 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase Vps53_N PF04100.12 CBY15610.1 - 1.6e-101 340.0 12.5 2.8e-101 339.2 12.5 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 CBY15610.1 - 7.3e-05 22.2 4.8 0.0003 20.2 4.5 2.2 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF4855 PF16147.5 CBY15610.1 - 0.13 11.4 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) DUF1366 PF07104.11 CBY15610.1 - 0.14 11.9 1.5 0.46 10.2 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) FUSC PF04632.12 CBY15610.1 - 0.32 9.5 0.6 0.52 8.8 0.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family MnmE_helical PF12631.7 CBY15610.1 - 0.35 11.0 11.1 0.21 11.8 7.6 2.4 2 1 0 2 2 2 0 MnmE helical domain Sec8_exocyst PF04048.14 CBY15610.1 - 0.5 10.2 6.3 0.21 11.5 2.0 2.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain MCPsignal PF00015.21 CBY15610.1 - 0.59 9.9 6.3 0.31 10.8 3.4 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ABC_tran_CTD PF16326.5 CBY15610.1 - 1.1 9.5 7.6 25 5.2 0.0 4.0 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF489 PF04356.12 CBY15610.1 - 1.9 8.5 7.7 14 5.6 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF489) Miff PF05644.11 CBY15611.1 - 4.5e-06 26.5 0.9 0.0095 15.6 0.4 2.4 1 1 0 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff Methyltransf_4 PF02390.17 CBY15611.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase HNF-1_N PF04814.13 CBY15613.1 - 1.7e-10 41.9 0.1 2.2e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1_N PF04814.13 CBY15614.1 - 1.9e-09 38.5 0.1 2.5e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Skp1 PF01466.19 CBY15618.1 - 0.0078 16.3 1.7 0.037 14.1 1.7 2.2 1 0 0 1 1 1 1 Skp1 family, dimerisation domain DUF961 PF06125.11 CBY15618.1 - 0.15 12.4 1.0 2.6 8.4 0.1 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF961) Glyco_transf_7N PF13733.6 CBY15620.1 - 1.1e-52 177.3 0.5 1.8e-52 176.5 0.5 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY15620.1 - 5.6e-20 70.8 0.0 1.3e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RL11D PF11088.8 CBY15620.1 - 0.017 15.4 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 AF-4 PF05110.13 CBY15622.1 - 0.062 11.4 24.0 0.062 11.4 24.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein BAF1_ABF1 PF04684.13 CBY15622.1 - 0.065 12.3 16.9 0.074 12.1 16.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Rgp1 PF08737.10 CBY15622.1 - 0.49 9.5 10.9 0.76 8.9 10.9 1.4 1 0 0 1 1 1 0 Rgp1 Peptidase_S46 PF10459.9 CBY15622.1 - 7.4 5.1 23.4 8.7 4.8 23.4 1.2 1 0 0 1 1 1 0 Peptidase S46 SHNi-TPR PF10516.9 CBY15623.1 - 0.045 13.2 2.3 5.1 6.6 0.1 3.5 3 0 0 3 3 3 0 SHNi-TPR HPIP PF15226.6 CBY15623.1 - 0.2 12.1 1.5 6.2 7.2 0.1 2.6 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family PsiA PF06952.11 CBY15623.1 - 3.5 6.8 9.4 0.16 11.2 0.5 2.6 2 0 0 2 2 2 0 PsiA protein MCC-bdg_PDZ PF10506.9 CBY15623.1 - 8.8 6.4 14.4 0.24 11.5 1.4 4.0 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Baculo_PEP_C PF04513.12 CBY15624.1 - 0.052 13.6 2.7 0.081 13.0 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Duo1 PF08651.10 CBY15624.1 - 0.27 11.1 9.2 0.41 10.4 1.4 2.8 2 1 1 3 3 3 0 DASH complex subunit Duo1 Rootletin PF15035.6 CBY15624.1 - 1.4 8.9 22.4 0.92 9.5 18.0 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 CBY15624.1 - 4.6 7.5 9.7 3 8.1 0.1 3.7 3 1 1 4 4 4 0 Homeobox associated leucine zipper Cupin_8 PF13621.6 CBY15625.1 - 2.3e-26 93.0 0.0 8.9e-18 64.9 0.0 2.1 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 CBY15625.1 - 5.6e-07 29.3 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 CBY15625.1 - 0.036 14.5 0.0 0.074 13.5 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_1 PF00190.22 CBY15625.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin LRR_8 PF13855.6 CBY15626.1 - 0.06 13.1 0.3 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Leucine rich repeat CHGN PF05679.16 CBY15627.1 - 1e-14 54.3 0.2 1e-14 54.3 0.2 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY15627.1 - 6.6e-09 35.3 0.6 8.5e-09 35.0 0.6 1.2 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Phage_base_V PF04717.12 CBY15629.1 - 0.077 12.9 0.3 0.54 10.2 0.1 2.1 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector Plectin PF00681.20 CBY15631.1 - 1.4e-22 79.3 0.0 1.9e-07 30.8 0.0 4.4 3 1 1 4 4 4 4 Plectin repeat Ion_trans PF00520.31 CBY15632.1 - 1.4e-19 70.3 14.1 3.4e-16 59.2 3.5 2.2 2 0 0 2 2 2 2 Ion transport protein bZIP_1 PF00170.21 CBY15634.1 - 2.6e-09 37.0 8.0 4.9e-09 36.1 8.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY15634.1 - 4.4e-07 29.9 10.6 4.4e-07 29.9 10.6 2.7 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY15634.1 - 1.7e-05 25.3 5.6 3.8e-05 24.1 5.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF5082 PF16888.5 CBY15634.1 - 0.017 15.4 0.8 0.017 15.4 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) EMP24_GP25L PF01105.24 CBY15634.1 - 0.1 12.6 1.4 0.22 11.4 1.4 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.15 CBY15634.1 - 8.1 6.3 8.9 0.26 11.1 1.3 2.2 2 1 1 3 3 3 0 Septum formation initiator DnaJ_CXXCXGXG PF00684.19 CBY15635.1 - 4.5e-05 23.7 18.3 0.00031 21.1 19.0 2.1 1 1 1 2 2 2 2 DnaJ central domain Coiled PF05710.12 CBY15635.1 - 0.14 13.0 4.5 2.6 8.9 0.2 2.2 1 1 1 2 2 2 0 Coiled coil I-EGF_1 PF18372.1 CBY15635.1 - 0.26 11.4 19.9 1.8 8.7 5.0 2.4 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 DUF1356 PF07092.12 CBY15635.1 - 0.31 10.3 6.6 2 7.6 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) PRR20 PF15708.5 CBY15635.1 - 2.1 8.2 4.1 2 8.3 3.5 1.3 1 1 0 1 1 1 0 Proline-rich protein family 20 Anti-TRAP PF15777.5 CBY15635.1 - 3.9 7.5 16.5 1.1 9.3 2.5 3.5 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Vps23_core PF09454.10 CBY15636.1 - 0.032 14.2 0.2 0.063 13.2 0.2 1.4 1 0 0 1 1 1 0 Vps23 core domain Nop14 PF04147.12 CBY15636.1 - 3.2 5.9 19.2 3.4 5.7 19.2 1.1 1 0 0 1 1 1 0 Nop14-like family fn3_4 PF16794.5 CBY15637.1 - 9.9e-28 96.1 0.0 1.8e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Fibronectin-III type domain ATG16 PF08614.11 CBY15637.1 - 0.0055 17.0 8.5 0.0055 17.0 8.5 2.4 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF4047 PF13256.6 CBY15637.1 - 0.26 11.5 9.2 0.028 14.6 4.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF1043 PF06295.12 CBY15637.1 - 0.32 11.0 7.0 1.1 9.3 7.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) UPF0242 PF06785.11 CBY15637.1 - 0.52 10.4 14.1 0.069 13.2 9.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 CBY15637.1 - 3.3 8.3 19.6 0.17 12.4 2.9 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region ING PF12998.7 CBY15637.1 - 5.4 7.7 9.9 2.9 8.5 6.4 2.4 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding LTXXQ PF07813.12 CBY15637.1 - 8.8 7.1 8.1 1.3 9.8 3.6 2.1 2 0 0 2 2 2 0 LTXXQ motif family protein Lyase_1 PF00206.20 CBY15638.1 - 2e-12 47.1 0.1 2e-09 37.3 0.0 2.7 2 1 1 3 3 3 2 Lyase ASL_C2 PF14698.6 CBY15638.1 - 1e-09 39.0 0.0 2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal BCS1_N PF08740.11 CBY15639.1 - 1.1e-08 35.3 0.0 1.5e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 BCS1 N terminal DUF4082 PF13313.6 CBY15639.1 - 0.056 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) La PF05383.17 CBY15640.1 - 2.8e-19 68.9 0.2 7.7e-19 67.5 0.1 1.8 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 CBY15640.1 - 3.5e-12 46.0 0.2 8e-12 44.8 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY15640.1 - 2e-10 40.6 3.9 6.3e-08 32.6 0.2 2.5 2 0 0 2 2 2 2 RNA binding motif PHM7_cyt PF14703.6 CBY15640.1 - 0.078 13.2 1.6 0.2 11.9 1.6 1.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Methyltransf_25 PF13649.6 CBY15641.1 - 2.8e-11 44.0 0.0 7.4e-11 42.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY15641.1 - 3.8e-11 43.0 0.0 7.6e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY15641.1 - 2.2e-09 37.8 0.0 6.5e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CBY15641.1 - 3.4e-09 36.5 0.1 5.6e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CBY15641.1 - 1.3e-07 31.6 0.0 8.3e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBY15641.1 - 1.5e-05 24.1 0.0 2.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 CBY15641.1 - 2.3e-05 24.0 0.1 3.6e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CBY15641.1 - 3.1e-05 23.4 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5_C PF17286.2 CBY15641.1 - 3.9e-05 23.6 0.0 5.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_12 PF08242.12 CBY15641.1 - 0.00015 22.4 0.0 0.00029 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CBY15641.1 - 0.00022 21.1 0.1 0.00035 20.4 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 CBY15641.1 - 0.00028 20.9 0.2 0.00058 19.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CBY15641.1 - 0.00058 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_2 PF00891.18 CBY15641.1 - 0.0014 18.0 0.4 0.0038 16.5 0.1 1.9 3 0 0 3 3 3 1 O-methyltransferase domain Methyltransf_24 PF13578.6 CBY15641.1 - 0.0018 19.3 0.0 0.0043 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CBY15641.1 - 0.0022 17.4 1.2 0.0081 15.6 1.2 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.19 CBY15641.1 - 0.0025 18.0 0.1 0.0069 16.5 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 CBY15641.1 - 0.0085 15.8 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DOT1 PF08123.13 CBY15641.1 - 0.017 14.6 0.2 0.09 12.3 0.0 2.0 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 CBY15641.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 CBY15641.1 - 0.048 13.5 0.2 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_4 PF02390.17 CBY15641.1 - 0.053 13.0 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase CHDCT2 PF08074.11 CBY15642.1 - 6.4e-76 254.3 1.3 2.2e-75 252.6 1.3 2.0 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain SNF2_N PF00176.23 CBY15642.1 - 9.2e-58 195.6 0.4 2.5e-57 194.2 0.2 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain DUF1086 PF06461.11 CBY15642.1 - 3.8e-37 127.2 0.1 1.6e-36 125.2 0.0 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) Helicase_C PF00271.31 CBY15642.1 - 1e-21 77.3 0.0 2.5e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1087 PF06465.13 CBY15642.1 - 5.3e-14 52.0 4.5 2.6e-13 49.8 4.5 2.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) Chromo PF00385.24 CBY15642.1 - 9.2e-14 51.1 8.5 5e-11 42.3 1.0 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CBY15642.1 - 1.2e-12 48.1 0.1 3.9e-11 43.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PHD PF00628.29 CBY15642.1 - 2.7e-11 43.2 5.5 2.7e-11 43.2 5.5 2.1 2 0 0 2 2 2 1 PHD-finger HDA2-3 PF11496.8 CBY15642.1 - 9e-06 25.1 0.3 9e-06 25.1 0.3 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CBY15642.1 - 0.0044 16.8 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-HC5HC2H PF13771.6 CBY15642.1 - 0.0047 17.1 0.8 0.017 15.4 0.5 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain Zf_RING PF16744.5 CBY15642.1 - 0.0091 16.1 2.5 0.014 15.5 0.8 2.2 2 0 0 2 2 2 1 KIAA1045 RING finger zf-HC5HC2H_2 PF13832.6 CBY15642.1 - 0.0094 16.1 0.1 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain AAA_22 PF13401.6 CBY15642.1 - 0.16 12.3 0.1 0.94 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain C1_1 PF00130.22 CBY15642.1 - 0.2 11.6 1.0 0.52 10.2 1.0 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CHDNT PF08073.12 CBY15642.1 - 0.36 10.8 1.7 2.4 8.2 0.0 3.3 4 0 0 4 4 4 0 CHDNT (NUC034) domain ADK_lid PF05191.14 CBY15642.1 - 2 8.5 7.4 0.86 9.6 3.1 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid PHD_4 PF16866.5 CBY15642.1 - 3.4 7.8 5.9 11 6.2 5.9 1.9 1 0 0 1 1 1 0 PHD-finger DEAD PF00270.29 CBY15643.1 - 1.7e-44 151.7 0.9 1.7e-44 151.7 0.9 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY15643.1 - 3.7e-27 94.9 0.1 8.2e-26 90.5 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBY15643.1 - 2.3e-15 56.6 0.0 4.7e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBY15643.1 - 7.1e-08 32.6 0.0 7.1e-08 32.6 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Cullin PF00888.22 CBY15644.1 - 3e-122 409.3 8.0 3.5e-122 409.1 8.0 1.0 1 0 0 1 1 1 1 Cullin family EGF PF00008.27 CBY15645.1 - 3.7e-11 43.1 25.7 5e-07 29.9 3.7 3.3 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 CBY15645.1 - 1.9e-06 28.3 15.6 0.00013 22.5 2.7 3.9 3 1 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.13 CBY15645.1 - 0.001 19.4 30.1 0.015 15.6 8.2 3.2 3 0 0 3 3 3 2 EGF-like domain cEGF PF12662.7 CBY15645.1 - 0.0034 17.3 19.6 0.0072 16.2 4.1 3.6 3 0 0 3 3 3 2 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CBY15645.1 - 0.005 17.1 24.0 0.014 15.7 6.2 3.3 2 1 1 3 3 3 2 Pvs28 EGF domain FXa_inhibition PF14670.6 CBY15645.1 - 0.013 15.8 20.5 0.13 12.6 7.0 3.4 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site KDZ PF18758.1 CBY15645.1 - 0.018 14.7 0.8 0.021 14.4 0.8 1.2 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase EGF_CA PF07645.15 CBY15645.1 - 0.067 13.4 28.7 0.17 12.2 8.5 3.3 2 1 1 3 3 3 0 Calcium-binding EGF domain Laminin_EGF PF00053.24 CBY15645.1 - 0.27 11.4 24.4 0.088 13.0 5.6 3.2 2 1 1 3 3 3 0 Laminin EGF domain DUF2997 PF11211.8 CBY15645.1 - 0.4 10.5 3.4 3.4 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) EGF_3 PF12947.7 CBY15645.1 - 0.44 10.8 24.9 0.17 12.1 4.1 3.6 3 1 0 3 3 3 0 EGF domain Pkinase PF00069.25 CBY15646.1 - 2.2e-18 66.6 0.0 2.8e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15646.1 - 6.2e-13 48.6 0.0 7.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY15646.1 - 0.00053 18.9 0.0 0.0024 16.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBY15646.1 - 0.0021 18.0 0.0 0.0023 17.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY15646.1 - 0.0058 16.0 0.0 0.0071 15.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like GST_C_3 PF14497.6 CBY15649.1 - 1.1e-08 35.2 0.3 1.8e-08 34.5 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY15649.1 - 5.2e-05 23.5 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY15649.1 - 0.00076 19.7 0.0 0.0015 18.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY15649.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FTCD_C PF04961.12 CBY15649.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase WD40 PF00400.32 CBY15650.1 - 3.6e-10 40.3 2.6 0.063 14.2 0.0 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY15650.1 - 1.5e-08 34.8 0.0 0.051 13.9 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain FANCI_S2 PF14676.6 CBY15650.1 - 0.043 14.1 0.2 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 FANCI solenoid 2 AAA PF00004.29 CBY15651.1 - 5.9e-32 110.9 0.0 1.2e-31 109.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY15651.1 - 5.7e-07 29.9 0.1 3.2e-06 27.4 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CBY15651.1 - 4.2e-05 24.0 0.0 0.00019 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CBY15651.1 - 9.7e-05 22.5 0.0 0.00039 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBY15651.1 - 0.0002 21.4 0.0 0.00061 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY15651.1 - 0.00038 20.0 0.0 0.00073 19.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 CBY15651.1 - 0.00045 20.2 0.1 0.0013 18.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CBY15651.1 - 0.0018 18.5 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBY15651.1 - 0.0018 18.0 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.6 CBY15651.1 - 0.0025 17.6 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY15651.1 - 0.0029 18.2 0.0 0.0079 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 CBY15651.1 - 0.0033 16.7 0.0 0.0057 15.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase_2 PF01637.18 CBY15651.1 - 0.0033 17.4 0.3 0.34 10.8 0.2 2.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 CBY15651.1 - 0.0042 16.4 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CBY15651.1 - 0.0051 17.2 0.1 0.013 15.8 0.1 1.9 1 1 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 CBY15651.1 - 0.0056 16.4 0.1 0.021 14.6 0.0 1.8 1 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 CBY15651.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase PhoH PF02562.16 CBY15651.1 - 0.0062 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein TsaE PF02367.17 CBY15651.1 - 0.0064 16.5 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CBY15651.1 - 0.0068 16.2 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBY15651.1 - 0.0069 15.8 0.0 0.051 12.9 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CBY15651.1 - 0.0081 15.5 0.7 0.19 11.1 0.0 2.5 1 1 1 2 2 2 1 KaiC AAA_30 PF13604.6 CBY15651.1 - 0.013 15.3 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CBY15651.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 CBY15651.1 - 0.015 14.9 0.0 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBY15651.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 CBY15651.1 - 0.024 14.9 0.0 0.079 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF5101 PF17031.5 CBY15651.1 - 0.03 14.4 0.1 0.11 12.6 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) DnaB_C PF03796.15 CBY15651.1 - 0.032 13.5 0.1 1.2 8.5 0.0 2.1 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain ResIII PF04851.15 CBY15651.1 - 0.039 14.0 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 CBY15651.1 - 0.056 12.5 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ArsA_ATPase PF02374.15 CBY15651.1 - 0.058 12.6 0.1 1.2 8.3 0.0 2.5 2 1 0 2 2 2 0 Anion-transporting ATPase PduV-EutP PF10662.9 CBY15651.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CBY15651.1 - 0.097 12.1 0.8 1.9 7.9 0.0 2.8 3 1 0 3 3 3 0 Bacterial TniB protein AAA_19 PF13245.6 CBY15651.1 - 0.11 12.8 0.4 0.6 10.4 0.4 2.1 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 CBY15651.1 - 0.12 12.5 0.1 0.98 9.5 0.0 2.3 2 1 0 2 2 2 0 Torsin AAA_23 PF13476.6 CBY15651.1 - 0.13 12.7 4.3 0.27 11.7 0.5 2.9 2 1 0 2 2 2 0 AAA domain Zot PF05707.12 CBY15651.1 - 0.15 11.7 0.0 0.75 9.4 0.0 2.0 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Sigma54_activat PF00158.26 CBY15651.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain ODR4-like PF14778.6 CBY15652.1 - 5.7e-16 58.4 0.3 6e-15 55.1 0.3 2.1 1 1 0 1 1 1 1 Olfactory receptor 4-like AKAP95 PF04988.12 CBY15652.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Pro_isomerase PF00160.21 CBY15653.1 - 1.9e-17 64.0 0.1 2.2e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BORG_CEP PF14957.6 CBY15654.1 - 0.00088 20.4 0.3 0.0014 19.8 0.3 1.4 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.28 CBY15654.1 - 0.0027 18.0 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain zf-FLZ PF04570.14 CBY15657.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 zf-AN1 PF01428.16 CBY15659.1 - 3.4e-19 68.7 27.0 1.4e-10 41.1 9.5 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger Amidase PF01425.21 CBY15659.1 - 6.1e-15 55.1 0.7 2.3e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Amidase Transp_Tc5_C PF04236.15 CBY15659.1 - 0.0026 18.1 22.0 0.024 15.0 4.2 3.1 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain C5HCH PF17982.1 CBY15659.1 - 7.7 6.8 15.7 9.8 6.4 2.1 3.0 2 1 0 2 2 2 0 NSD Cys-His rich domain Lectin_C PF00059.21 CBY15660.1 - 4.2e-11 43.5 0.2 1e-10 42.3 0.2 1.6 1 0 0 1 1 1 1 Lectin C-type domain Trypsin PF00089.26 CBY15661.1 - 6.5e-05 22.8 0.1 0.00011 22.1 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CBY15662.1 - 1.6e-18 67.4 0.1 2.5e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Trypsin Y_phosphatase PF00102.27 CBY15663.1 - 2e-18 66.8 0.1 3.4e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UAA PF08449.11 CBY15664.1 - 3.9e-51 174.1 12.8 4.6e-51 173.8 12.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBY15664.1 - 5.9e-15 55.6 14.8 1.5e-07 31.6 6.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CBY15664.1 - 8e-11 41.8 11.0 9.5e-10 38.3 11.1 1.9 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 CBY15664.1 - 0.00078 18.7 3.2 0.37 9.9 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter TMEM234 PF10639.9 CBY15664.1 - 0.029 14.4 3.3 2.6 8.1 0.2 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 7tm_1 PF00001.21 CBY15664.1 - 2.7 7.2 9.7 0.36 10.1 3.9 2.0 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) zf-C3HC4_3 PF13920.6 CBY15665.1 - 3.7e-09 36.3 11.7 5.3e-09 35.8 11.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY15665.1 - 3.2e-06 27.4 15.2 4.9e-06 26.8 15.2 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBY15665.1 - 5.7e-06 26.1 12.5 1e-05 25.3 12.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY15665.1 - 3.7e-05 23.5 14.9 6.6e-05 22.7 14.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY15665.1 - 0.00046 20.1 15.8 0.0011 18.9 15.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY15665.1 - 0.00065 19.5 15.3 0.001 18.8 15.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY15665.1 - 0.0035 17.3 12.0 0.007 16.4 12.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger DUF3584 PF12128.8 CBY15665.1 - 0.12 9.9 13.7 0.13 9.7 13.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-P11 PF03854.14 CBY15665.1 - 0.14 11.8 6.1 0.25 11.0 6.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger DUF489 PF04356.12 CBY15665.1 - 0.23 11.4 2.0 0.53 10.3 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF489) DUF4407 PF14362.6 CBY15665.1 - 0.27 10.6 12.0 0.32 10.3 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CBY15665.1 - 0.33 9.8 17.0 0.41 9.5 17.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_10 PF16685.5 CBY15665.1 - 0.77 9.9 9.6 2.1 8.5 9.6 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 ApoO PF09769.9 CBY15665.1 - 1 9.3 2.8 3.1 7.8 2.8 1.7 1 1 0 1 1 1 0 Apolipoprotein O Endonuc_Holl PF10107.9 CBY15665.1 - 1.5 8.6 15.0 0.9 9.4 11.9 1.8 1 1 1 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF4094 PF13334.6 CBY15665.1 - 2 8.9 5.5 3.2 8.2 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) DUF1664 PF07889.12 CBY15665.1 - 2.5 8.2 8.0 3.6 7.6 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Membralin PF09746.9 CBY15665.1 - 3.3 6.7 9.4 3.9 6.4 9.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein ALMT PF11744.8 CBY15665.1 - 6.5 5.5 11.0 7.4 5.3 11.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter FeoB_Cyto PF17910.1 CBY15665.1 - 7.2 7.2 10.9 15 6.2 10.9 1.6 1 1 0 1 1 1 0 FeoB cytosolic helical domain DUF4337 PF14235.6 CBY15665.1 - 8.1 6.5 11.9 9.5 6.3 11.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Glyco_transf_43 PF03360.16 CBY15666.1 - 9e-52 175.9 0.0 1e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 RFX_DNA_binding PF02257.15 CBY15668.1 - 2.6e-32 111.3 0.1 6.1e-32 110.1 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain STI1 PF17830.1 CBY15668.1 - 0.028 14.3 1.2 0.067 13.1 0.6 1.9 2 0 0 2 2 2 0 STI1 domain DUF4032 PF13224.6 CBY15668.1 - 0.059 13.3 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) zf-RING_UBOX PF13445.6 CBY15669.1 - 1.6e-07 31.2 7.6 1.6e-07 31.2 7.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY15669.1 - 3e-07 30.3 10.4 7.3e-07 29.1 10.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY15669.1 - 8.6e-07 29.2 10.1 1.8e-06 28.1 10.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY15669.1 - 9.4e-07 28.6 11.1 2.3e-06 27.4 11.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY15669.1 - 0.00066 19.4 6.8 0.0017 18.1 6.8 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CBY15669.1 - 0.00078 19.6 2.1 0.00078 19.6 2.1 2.4 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBY15669.1 - 0.0024 17.7 10.6 0.0051 16.6 9.9 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY15669.1 - 0.025 14.4 15.1 0.43 10.5 15.1 2.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY15669.1 - 0.033 14.5 11.5 0.045 14.0 9.8 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger domain PspA_IM30 PF04012.12 CBY15669.1 - 0.07 12.7 5.9 1.9 8.0 0.3 2.1 2 0 0 2 2 2 0 PspA/IM30 family TMF_TATA_bd PF12325.8 CBY15669.1 - 0.11 12.8 11.7 7.7 6.8 12.5 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF5591 PF17884.1 CBY15669.1 - 0.12 12.3 0.0 0.54 10.1 0.0 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5591) zf-RING_11 PF17123.5 CBY15669.1 - 0.25 11.1 10.0 0.062 13.1 6.4 2.0 2 0 0 2 2 2 0 RING-like zinc finger Wbp11 PF09429.10 CBY15669.1 - 0.44 11.0 8.2 0.11 12.9 2.3 2.3 1 1 1 2 2 2 0 WW domain binding protein 11 DUF641 PF04859.12 CBY15669.1 - 1.1 9.6 9.8 0.88 9.9 3.8 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3134 PF11332.8 CBY15669.1 - 1.3 9.4 4.2 1.4 9.3 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3134) LXG PF04740.12 CBY15669.1 - 1.7 8.3 9.1 0.24 11.1 1.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Med4 PF10018.9 CBY15669.1 - 2.9 7.5 9.6 0.73 9.5 3.5 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 FYVE PF01363.21 CBY15669.1 - 3.6 7.8 12.2 23 5.2 12.0 2.4 1 1 0 1 1 1 0 FYVE zinc finger Tombus_P19 PF03220.13 CBY15670.1 - 0.047 13.4 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Tombusvirus P19 core protein Chlam_PMP PF02415.17 CBY15670.1 - 0.061 13.8 0.0 0.33 11.5 0.0 2.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat APG6_N PF17675.1 CBY15673.1 - 0.0014 19.2 13.5 0.0017 18.9 13.5 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF4094 PF13334.6 CBY15673.1 - 0.25 11.8 5.2 0.3 11.5 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Ribosomal_L27e PF01777.18 CBY15674.1 - 3.5e-22 78.5 1.2 1.2e-21 76.8 1.9 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 CBY15674.1 - 7.5e-05 22.5 0.1 0.00016 21.5 0.1 1.5 1 0 0 1 1 1 1 KOW motif FGGY_C PF02782.16 CBY15675.1 - 5.5e-29 101.3 0.0 1.7e-27 96.4 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CBY15675.1 - 2.2e-05 24.1 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIS13 PF08202.11 CBY15676.1 - 1.8e-05 24.2 2.9 2.5e-05 23.7 2.9 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family FPP PF05911.11 CBY15676.1 - 0.012 13.9 6.9 0.015 13.6 6.2 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil CENP-Q PF13094.6 CBY15676.1 - 0.017 15.4 8.0 0.037 14.2 8.0 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin_1 PF12718.7 CBY15676.1 - 0.024 14.8 6.2 0.11 12.7 1.5 2.8 2 1 1 3 3 3 0 Tropomyosin like Sec34 PF04136.15 CBY15676.1 - 0.029 14.2 6.8 0.43 10.4 2.2 2.2 1 1 1 2 2 2 0 Sec34-like family HIP1_clath_bdg PF16515.5 CBY15676.1 - 0.03 14.9 13.0 1.1 9.9 6.1 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 CBY15676.1 - 0.053 13.6 3.6 0.075 13.1 1.5 2.2 2 1 0 2 2 2 0 TolA binding protein trimerisation Med4 PF10018.9 CBY15676.1 - 0.066 12.9 5.6 0.19 11.4 1.2 2.3 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4404 PF14357.6 CBY15676.1 - 0.15 12.8 4.8 0.21 12.3 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Fzo_mitofusin PF04799.13 CBY15676.1 - 0.17 11.5 3.4 7.7 6.0 0.0 2.4 2 1 0 2 2 2 0 fzo-like conserved region GAS PF13851.6 CBY15676.1 - 0.17 11.2 8.4 0.32 10.3 4.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FAA_hydro_N_2 PF18288.1 CBY15676.1 - 0.22 12.0 2.3 0.33 11.4 0.7 2.1 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DUF2203 PF09969.9 CBY15676.1 - 0.25 12.1 5.0 0.82 10.4 1.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SesA PF17107.5 CBY15676.1 - 0.41 10.9 3.6 3.4 7.9 0.1 2.7 1 1 2 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FliD_N PF02465.18 CBY15676.1 - 0.52 11.0 5.4 6.9 7.4 2.1 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus YabA PF06156.13 CBY15676.1 - 0.58 10.8 3.4 13 6.5 0.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF5082 PF16888.5 CBY15676.1 - 0.83 9.9 7.0 1.2 9.5 2.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Spc24 PF08286.11 CBY15676.1 - 0.88 9.8 8.3 15 5.9 8.3 2.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 CBY15676.1 - 1 9.9 16.0 0.35 11.4 9.7 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 CBY15676.1 - 1.5 8.6 11.9 0.34 10.7 7.2 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FapA PF03961.13 CBY15676.1 - 1.5 7.3 3.4 6.7 5.2 3.4 1.9 1 1 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 CBY15676.1 - 1.5 9.0 9.9 8.9 6.6 0.1 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3552 PF12072.8 CBY15676.1 - 1.9 7.8 8.9 3.1 7.2 4.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DivIC PF04977.15 CBY15676.1 - 2.4 8.0 5.9 1.9 8.3 1.7 2.6 3 0 0 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 CBY15676.1 - 2.4 8.3 7.0 15 5.8 1.3 2.9 3 0 0 3 3 3 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 CBY15676.1 - 2.8 8.0 14.6 1.3 9.1 7.7 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Herpes_UL6 PF01763.16 CBY15676.1 - 4.6 5.6 6.8 4.4 5.7 4.2 2.1 2 1 0 2 2 2 0 Herpesvirus UL6 like RabGAP-TBC PF00566.18 CBY15677.1 - 5.2e-29 101.4 0.3 5.2e-29 101.4 0.3 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Phage_rep_org_N PF09681.10 CBY15678.1 - 0.074 13.0 0.7 0.11 12.4 0.5 1.4 1 1 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Phage_Arf PF17585.2 CBY15678.1 - 0.54 10.2 2.7 0.33 10.9 0.8 1.7 1 1 1 2 2 2 0 Accessory recombination function protein Aa_trans PF01490.18 CBY15679.1 - 5e-11 41.9 5.4 5.7e-11 41.8 5.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBY15679.1 - 0.00016 20.8 2.5 0.0002 20.5 2.5 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF226 PF02890.14 CBY15680.1 - 0.0069 16.4 1.5 0.008 16.2 1.5 1.2 1 0 0 1 1 1 1 Borrelia family of unknown function DUF226 P66_CC PF16563.5 CBY15682.1 - 1.6e-06 27.6 1.3 1.6e-06 27.6 1.3 2.7 3 0 0 3 3 3 1 Coiled-coil and interaction region of P66A and P66B with MBD2 Synaphin PF05835.12 CBY15682.1 - 0.022 15.0 7.5 0.022 15.0 7.5 3.4 4 0 0 4 4 4 0 Synaphin protein GATA PF00320.27 CBY15682.1 - 0.024 14.2 1.4 0.051 13.2 1.4 1.5 1 0 0 1 1 1 0 GATA zinc finger LXG PF04740.12 CBY15682.1 - 0.03 14.0 0.2 0.03 14.0 0.2 3.5 4 0 0 4 4 4 0 LXG domain of WXG superfamily YlqD PF11068.8 CBY15682.1 - 0.046 14.1 0.2 0.046 14.1 0.2 3.5 3 1 0 3 3 3 0 YlqD protein Siva PF05458.12 CBY15682.1 - 0.21 11.2 2.1 0.37 10.5 0.2 2.2 1 1 1 2 2 2 0 Cd27 binding protein (Siva) AXE1 PF05448.12 CBY15682.1 - 0.28 9.8 1.8 0.59 8.8 1.8 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Helicase_C_4 PF13871.6 CBY15683.1 - 5.2e-84 282.1 0.0 6.3e-84 281.9 0.0 1.1 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue Helicase_C PF00271.31 CBY15683.1 - 0.063 13.6 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Helicase conserved C-terminal domain AAA_34 PF13872.6 CBY15684.1 - 5e-60 202.9 0.0 6.9e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Cortex-I_coil PF09304.10 CBY15687.1 - 0.28 11.4 7.8 0.11 12.7 1.8 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil ADIP PF11559.8 CBY15687.1 - 1 9.5 12.4 0.83 9.7 7.1 2.1 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 CBY15687.1 - 1.3 8.4 6.6 1.7 8.0 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 CBY15687.1 - 2.4 8.2 6.1 1.9 8.5 3.6 2.0 1 1 1 2 2 2 0 FlxA-like protein MIP PF00230.20 CBY15688.1 - 9.8e-45 153.0 7.0 1.2e-44 152.8 7.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 CBY15690.1 - 4.2e-12 46.0 0.4 1.4e-11 44.3 0.2 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15690.1 - 5.9e-09 35.6 0.0 2.6e-08 33.5 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kelch_6 PF13964.6 CBY15693.1 - 0.00084 19.5 1.6 1.1 9.6 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY15693.1 - 0.0024 17.8 0.2 7.4 6.7 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY15693.1 - 0.06 13.4 2.0 2.1 8.5 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY15693.1 - 0.063 13.3 0.0 0.063 13.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Sushi PF00084.20 CBY15694.1 - 6.8e-29 100.3 24.0 5.8e-08 33.2 3.4 4.8 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) VWA PF00092.28 CBY15694.1 - 5.2e-16 59.4 0.0 9.8e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY15694.1 - 1.9e-07 31.7 0.0 4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.21 CBY15694.1 - 0.0027 18.0 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Sushi PF00084.20 CBY15695.1 - 1.7e-42 143.8 56.1 6.1e-10 39.6 3.6 6.5 7 0 0 7 7 7 5 Sushi repeat (SCR repeat) HRM PF02793.22 CBY15695.1 - 6.6 7.1 36.8 3.2 8.1 2.4 5.5 4 1 1 5 5 5 0 Hormone receptor domain Sushi PF00084.20 CBY15696.1 - 6.3e-56 186.8 82.4 8.9e-11 42.2 7.0 8.4 8 0 0 8 8 8 8 Sushi repeat (SCR repeat) VWA PF00092.28 CBY15696.1 - 1.1e-25 90.8 0.0 1.5e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY15696.1 - 5.9e-14 52.6 0.0 8.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain HRM PF02793.22 CBY15696.1 - 0.0083 16.4 73.8 0.95 9.8 1.0 8.4 5 2 2 7 7 7 5 Hormone receptor domain zf-C2HC PF01530.18 CBY15697.1 - 1.1e-24 86.3 32.3 9e-13 48.2 8.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2HC type IBR PF01485.21 CBY15697.1 - 0.034 14.4 3.9 0.9 9.8 0.2 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Chitin_synth_2 PF03142.15 CBY15698.1 - 4.7e-12 45.3 5.4 7.4e-08 31.5 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 CBY15698.1 - 0.017 15.0 0.0 0.26 11.2 0.0 2.5 3 0 0 3 3 3 0 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY15698.1 - 0.27 11.1 13.8 0.016 15.1 6.7 2.6 2 1 0 2 2 2 0 Glycosyl transferase family group 2 Pkinase PF00069.25 CBY15699.1 - 1.5e-10 40.9 1.3 1.9e-10 40.5 1.3 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15699.1 - 6.4e-05 22.4 0.2 7.2e-05 22.2 0.2 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY15699.1 - 0.0017 18.4 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY15699.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DEC-1_N PF04625.13 CBY15701.1 - 0.18 10.8 0.9 0.4 9.6 0.1 1.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Aminotran_5 PF00266.19 CBY15703.1 - 3.5e-22 78.9 0.0 4.2e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V LysM PF01476.20 CBY15704.1 - 2e-06 27.7 0.0 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 LysM domain DUF3782 PF12644.7 CBY15704.1 - 0.13 12.4 0.0 3.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) HTH_Crp_2 PF13545.6 CBY15704.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DEAD_2 PF06733.15 CBY15705.1 - 8e-51 172.1 3.5 1.4e-50 171.4 3.5 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CBY15705.1 - 2.6e-45 154.7 0.0 4.6e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 CBY15705.1 - 2.8e-27 95.6 0.0 1.7e-22 80.0 0.0 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 CBY15705.1 - 5.2e-07 29.8 0.1 1e-05 25.6 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CBY15705.1 - 0.0059 15.4 0.3 0.74 8.5 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain AAA_11 PF13086.6 CBY15705.1 - 0.0067 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY15705.1 - 0.013 15.8 0.0 0.045 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CBY15705.1 - 0.043 13.3 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein EF-hand_1 PF00036.32 CBY15706.1 - 2e-16 58.2 8.5 4.4e-07 29.0 0.9 3.9 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY15706.1 - 2e-14 53.7 3.3 1.4e-06 28.7 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY15706.1 - 3.8e-14 51.3 3.8 1.4e-07 30.8 0.6 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBY15706.1 - 4.4e-10 39.3 4.9 0.016 15.0 0.1 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY15706.1 - 5.3e-08 32.0 7.8 0.00022 20.6 0.8 3.7 4 0 0 4 4 4 2 EF hand UPF0154 PF03672.13 CBY15706.1 - 0.00023 21.1 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 CBY15706.1 - 0.00088 20.1 0.1 0.0031 18.3 0.0 1.8 1 1 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY15706.1 - 0.036 14.4 0.6 0.67 10.3 0.1 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TYW3 PF02676.14 CBY15710.1 - 0.073 12.4 2.5 0.1 11.9 2.5 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 FCP1_C PF09309.10 CBY15710.1 - 1.7 8.4 16.2 2.1 8.2 16.2 1.0 1 0 0 1 1 1 0 FCP1, C-terminal zf-C3HC4_2 PF13923.6 CBY15711.1 - 3.7e-13 49.1 6.3 6.8e-13 48.2 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY15711.1 - 4.8e-13 49.2 6.7 8.2e-13 48.5 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY15711.1 - 2e-10 40.3 5.6 2e-10 40.3 5.6 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY15711.1 - 3.8e-10 39.9 7.8 1.1e-09 38.5 7.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBY15711.1 - 3.7e-08 33.3 4.7 4.7e-08 32.9 3.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY15711.1 - 4.6e-08 32.8 4.0 6.6e-08 32.3 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY15711.1 - 6.5e-07 29.0 3.4 1.7e-06 27.7 3.4 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBY15711.1 - 2.1e-06 27.8 5.9 3.6e-06 27.0 5.0 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CBY15711.1 - 2.7e-06 27.2 5.1 6.3e-06 26.1 5.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBY15711.1 - 7.6e-05 22.7 3.7 0.0003 20.8 4.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBY15711.1 - 8.7e-05 22.3 5.7 0.00015 21.6 5.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBY15711.1 - 0.00023 20.7 4.4 0.00037 20.1 4.4 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 CBY15711.1 - 0.0022 17.8 1.9 0.0035 17.2 1.9 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein RINGv PF12906.7 CBY15711.1 - 0.02 15.0 8.7 0.1 12.7 7.6 2.1 1 1 1 2 2 2 0 RING-variant domain zf-Nse PF11789.8 CBY15711.1 - 0.021 14.6 2.8 0.036 13.9 2.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Endonuclease_7 PF02945.15 CBY15711.1 - 0.049 13.5 3.3 0.14 12.1 3.3 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII zf-HC5HC2H_2 PF13832.6 CBY15711.1 - 0.053 13.7 3.1 0.13 12.5 3.1 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zinc_ribbon_16 PF17034.5 CBY15711.1 - 0.097 12.9 3.1 0.3 11.3 3.2 1.7 1 1 0 1 1 1 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 CBY15711.1 - 0.21 11.7 7.7 0.62 10.1 7.8 1.8 1 1 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 CBY15711.1 - 0.43 10.9 7.0 1.3 9.4 6.6 1.9 1 1 1 2 2 2 0 RING-like domain FANCL_C PF11793.8 CBY15711.1 - 1.5 9.0 8.8 19 5.5 8.8 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Phospholip_A2_1 PF00068.19 CBY15713.1 - 7.4e-08 32.9 0.3 7.4e-08 32.9 0.3 3.4 3 1 0 3 3 3 1 Phospholipase A2 zf-GRF PF06839.12 CBY15713.1 - 0.076 13.1 1.4 0.47 10.6 0.1 2.5 2 0 0 2 2 2 0 GRF zinc finger TFIIA PF03153.13 CBY15713.1 - 2.2 8.2 23.8 3.4 7.6 23.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CBY15713.1 - 4.7 5.6 24.2 6 5.3 24.2 1.2 1 0 0 1 1 1 0 Macoilin family Galactosyl_T PF01762.21 CBY15716.1 - 1.2e-16 61.1 0.1 1.7e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase LCCL PF03815.19 CBY15719.1 - 7.8e-11 42.0 0.0 1.6e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.25 CBY15719.1 - 9.3e-09 35.5 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF4919 PF16266.5 CBY15719.1 - 0.089 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) fn3 PF00041.21 CBY15720.1 - 3.5e-49 165.1 11.4 6.8e-15 55.2 0.0 6.4 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.16 CBY15720.1 - 8.5e-18 64.2 1.8 4.4e-07 29.9 0.1 4.8 5 0 0 5 5 5 3 Immunoglobulin I-set domain Bravo_FIGEY PF13882.6 CBY15720.1 - 3.5e-13 50.7 1.7 1.4e-12 48.8 1.7 2.2 1 0 0 1 1 1 1 Bravo-like intracellular region Ig_3 PF13927.6 CBY15720.1 - 6.6e-11 42.7 6.4 0.014 16.0 0.1 4.8 5 0 0 5 5 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY15720.1 - 1.1e-09 38.7 7.6 0.026 15.1 0.2 5.1 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 CBY15720.1 - 3.2e-07 30.6 0.3 0.3 11.4 0.1 3.7 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 CBY15720.1 - 1.3e-06 28.4 0.0 0.97 9.7 0.0 3.9 3 0 0 3 3 3 2 Immunoglobulin domain Interfer-bind PF09294.10 CBY15720.1 - 9.4e-06 25.9 0.9 2.8 8.3 0.0 5.3 6 0 0 6 6 6 1 Interferon-alpha/beta receptor, fibronectin type III Y_Y_Y PF07495.13 CBY15720.1 - 0.0027 17.6 0.9 8.4 6.4 0.0 5.0 5 0 0 5 5 5 1 Y_Y_Y domain V-set PF07686.17 CBY15720.1 - 0.0044 17.2 3.5 11 6.3 0.0 4.9 3 2 2 5 5 5 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 CBY15720.1 - 0.13 12.5 2.1 7.8 6.8 0.0 3.8 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 Sulfotransfer_1 PF00685.27 CBY15721.1 - 1.1e-15 57.8 0.0 3e-15 56.4 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY15721.1 - 6.4e-07 30.0 0.8 0.68 10.3 0.0 3.8 3 1 1 4 4 4 3 Sulfotransferase family Ion_trans_2 PF07885.16 CBY15722.1 - 9.9e-28 95.9 17.7 3.8e-14 52.4 1.1 3.5 3 1 1 4 4 4 3 Ion channel OATP PF03137.20 CBY15723.1 - 4.5e-28 97.9 10.1 4.9e-28 97.7 10.1 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Dynein_light PF01221.18 CBY15725.1 - 2.4e-13 50.2 0.0 3.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Kelch_2 PF07646.15 CBY15726.1 - 0.0018 18.2 1.6 0.42 10.7 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CBY15726.1 - 0.014 15.4 1.6 0.96 9.5 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY15726.1 - 0.041 14.2 3.1 0.66 10.3 0.1 3.7 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 CBY15726.1 - 0.071 13.1 0.6 6.8 6.8 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain LPD5 PF18799.1 CBY15730.1 - 0.0054 17.2 1.0 0.0064 16.9 1.0 1.3 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 5 DUF4412 PF14371.6 CBY15730.1 - 0.018 14.9 0.2 0.022 14.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) DHHC PF01529.20 CBY15732.1 - 0.43 10.7 5.0 1.8 8.6 1.6 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2207 PF09972.9 CBY15732.1 - 1.2 7.8 6.5 0.84 8.3 0.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Ydr279_N PF17745.1 CBY15733.1 - 0.018 15.3 0.0 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 Ydr279p protein triple barrel domain HSF_DNA-bind PF00447.17 CBY15733.1 - 0.16 12.6 4.1 1.6 9.4 3.5 2.6 2 1 0 2 2 2 0 HSF-type DNA-binding Rnk_N PF14760.6 CBY15734.1 - 0.17 12.4 0.7 0.34 11.4 0.7 1.5 1 0 0 1 1 1 0 Rnk N-terminus PFU PF09070.11 CBY15735.1 - 0.046 14.0 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Kelch_5 PF13854.6 CBY15735.1 - 0.07 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Kelch motif GH114_assoc PF14741.6 CBY15735.1 - 0.14 12.3 0.2 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Astacin PF01400.24 CBY15736.1 - 2.2e-27 95.9 0.4 2.2e-27 95.9 0.4 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Mucin PF01456.17 CBY15736.1 - 1.5e-06 28.3 36.4 2.1e-06 27.8 36.4 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein FSA_C PF10479.9 CBY15736.1 - 0.87 7.6 18.7 1.2 7.2 18.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AJAP1_PANP_C PF15298.6 CBY15736.1 - 4.2 7.5 25.9 7.3 6.8 25.9 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus MGC-24 PF05283.11 CBY15736.1 - 9.9 6.6 23.1 18 5.8 23.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-RING_UBOX PF13445.6 CBY15737.1 - 2.4e-06 27.5 3.1 2.4e-06 27.5 3.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY15737.1 - 4.5e-06 26.9 10.5 2.9e-05 24.3 7.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CBY15737.1 - 0.00018 21.4 13.2 0.0026 17.7 9.8 2.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY15737.1 - 0.0003 20.6 13.6 0.0019 18.1 10.5 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY15737.1 - 0.00051 19.9 15.7 0.0065 16.3 10.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY15737.1 - 0.00068 19.4 15.4 0.0045 16.8 11.0 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY15737.1 - 0.00098 18.9 9.0 0.14 12.0 6.3 2.5 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 CBY15737.1 - 0.0023 17.8 5.4 0.0023 17.8 5.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY15737.1 - 0.0034 17.2 16.6 0.039 13.8 4.6 3.2 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 IBR PF01485.21 CBY15737.1 - 0.0079 16.4 9.3 0.038 14.2 6.2 2.4 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain CENP-F_leu_zip PF10473.9 CBY15737.1 - 0.022 14.8 10.8 0.052 13.6 10.8 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SUKH-3 PF14433.6 CBY15737.1 - 0.039 14.4 0.1 0.074 13.5 0.1 1.5 1 1 0 1 1 1 0 SUKH-3 immunity protein FYVE PF01363.21 CBY15737.1 - 0.14 12.3 8.5 0.55 10.4 4.1 2.3 2 0 0 2 2 2 0 FYVE zinc finger DUF1272 PF06906.11 CBY15737.1 - 0.34 11.0 11.5 22 5.2 7.4 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1272) DUF1664 PF07889.12 CBY15737.1 - 0.36 10.9 4.5 0.69 10.0 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 CBY15737.1 - 0.38 11.2 12.0 0.099 13.1 8.3 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) VPS38 PF17649.1 CBY15737.1 - 0.38 9.6 7.5 0.5 9.2 7.5 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Vps39_2 PF10367.9 CBY15737.1 - 0.47 10.9 0.0 0.47 10.9 0.0 3.4 3 1 0 3 3 2 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_jaz PF12171.8 CBY15737.1 - 0.52 10.7 6.0 1.4 9.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rtf2 PF04641.12 CBY15737.1 - 0.55 9.6 14.9 0.015 14.7 3.3 2.6 1 1 1 2 2 2 0 Rtf2 RING-finger TolA_bind_tri PF16331.5 CBY15737.1 - 0.71 10.0 9.8 0.18 11.9 3.3 2.9 2 2 1 3 3 3 0 TolA binding protein trimerisation DUF16 PF01519.16 CBY15737.1 - 0.76 10.3 8.1 1.4 9.4 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 zf-C3HC4_4 PF15227.6 CBY15737.1 - 0.78 9.9 10.1 2.2 8.5 6.9 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBY15737.1 - 1.2 9.5 11.8 5.2 7.4 7.6 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain TMPIT PF07851.13 CBY15737.1 - 1.5 8.0 5.6 2 7.6 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 CBY15737.1 - 1.8 6.4 4.4 1.8 6.4 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DLP_helical PF18709.1 CBY15737.1 - 2.3 7.3 9.6 13 4.9 6.0 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain KxDL PF10241.9 CBY15737.1 - 3.4 8.0 8.2 2.1 8.7 5.6 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF724 PF05266.14 CBY15737.1 - 3.4 7.4 11.3 5.8 6.7 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 CBY15737.1 - 3.6 7.9 18.0 6.9 6.9 9.2 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2703 PF10865.8 CBY15737.1 - 4.2 7.6 10.1 0.58 10.4 5.6 1.9 2 1 0 2 2 1 0 Domain of unknown function (DUF2703) Zn_Tnp_IS91 PF14319.6 CBY15737.1 - 4.2 7.5 14.0 31 4.7 10.2 2.6 2 1 0 2 2 2 0 Transposase zinc-binding domain Spc7 PF08317.11 CBY15737.1 - 6.2 5.6 17.6 0.39 9.5 12.5 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1043 PF06295.12 CBY15737.1 - 7 6.7 7.9 16 5.5 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Macoilin PF09726.9 CBY15737.1 - 7.1 5.1 12.9 0.16 10.5 6.7 1.3 2 0 0 2 2 2 0 Macoilin family COG4 PF08318.12 CBY15738.1 - 5.9e-62 209.7 4.6 4.2e-61 206.9 4.6 1.9 1 1 0 1 1 1 1 COG4 transport protein Pro_isomerase PF00160.21 CBY15739.1 - 1e-10 42.1 0.1 3.5e-10 40.4 0.1 2.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF667 PF05018.13 CBY15740.1 - 6.4e-95 316.2 0.9 7.1e-95 316.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.25 CBY15741.1 - 4.2e-15 55.8 0.6 6.8e-15 55.1 0.4 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY15741.1 - 1.4e-05 24.1 0.2 7.3e-05 21.7 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CBY15741.1 - 0.00021 20.7 0.1 0.00033 20.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY15741.1 - 0.01 15.8 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 CBY15742.1 - 8.8e-21 73.2 37.6 0.00015 22.0 3.3 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY15742.1 - 2e-18 65.5 34.0 0.0008 20.1 1.0 6.0 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY15742.1 - 4.7e-09 36.3 33.6 0.0053 17.1 0.8 5.6 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY15742.1 - 0.00027 20.9 32.9 0.027 14.5 3.3 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 CBY15742.1 - 0.00056 20.1 11.2 0.034 14.4 0.1 4.4 4 0 0 4 4 4 2 zinc-ribbon IBR PF01485.21 CBY15742.1 - 0.0085 16.3 3.9 0.0085 16.3 3.9 3.5 1 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-C2H2_11 PF16622.5 CBY15742.1 - 0.014 15.1 0.6 0.014 15.1 0.6 4.8 5 0 0 5 5 4 0 zinc-finger C2H2-type PyrI_C PF02748.15 CBY15742.1 - 0.041 13.8 3.6 0.055 13.4 1.8 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_aberr PF17017.5 CBY15742.1 - 0.047 13.8 6.9 0.75 9.9 6.3 2.4 2 0 0 2 2 2 0 Aberrant zinc-finger TerY_C PF15616.6 CBY15742.1 - 0.074 13.2 2.8 0.34 11.0 0.6 2.5 1 1 1 2 2 2 0 TerY-C metal binding domain zf-3CxxC_2 PF17180.4 CBY15742.1 - 0.17 12.6 0.0 0.17 12.6 0.0 4.3 4 1 0 4 4 2 0 Zinc-binding domain zf-ribbon_3 PF13248.6 CBY15742.1 - 0.18 11.3 13.6 4.7 6.8 0.5 4.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-Di19 PF05605.12 CBY15742.1 - 0.2 12.0 21.1 0.75 10.1 1.5 3.9 1 1 4 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 CBY15742.1 - 0.2 11.7 12.1 8.5 6.4 0.1 3.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YhfH PF14149.6 CBY15742.1 - 0.34 10.9 8.9 6 6.9 0.4 3.9 4 0 0 4 4 4 0 YhfH-like protein zf-met PF12874.7 CBY15742.1 - 0.45 11.0 0.1 0.45 11.0 0.1 5.4 6 0 0 6 6 4 0 Zinc-finger of C2H2 type Trm112p PF03966.16 CBY15742.1 - 0.53 10.9 3.0 4.1 8.1 0.6 3.3 2 2 1 3 3 3 0 Trm112p-like protein CpXC PF14353.6 CBY15742.1 - 0.68 10.0 17.8 11 6.1 0.3 4.5 1 1 3 4 4 4 0 CpXC protein Elf1 PF05129.13 CBY15742.1 - 0.79 9.8 11.5 14 5.9 5.7 3.6 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Terminase_GpA PF05876.12 CBY15742.1 - 1.1 7.7 8.9 0.11 11.0 1.0 2.2 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-C2H2_8 PF15909.5 CBY15742.1 - 1.2 9.5 20.1 2 8.8 3.1 4.0 3 1 2 5 5 4 0 C2H2-type zinc ribbon zf-RING_7 PF02591.15 CBY15742.1 - 1.2 9.3 10.6 25 5.2 0.1 5.2 5 0 0 5 5 5 0 C4-type zinc ribbon domain Mu-like_Com PF10122.9 CBY15742.1 - 4.4 6.8 9.5 7.8 6.0 5.8 3.1 2 1 0 2 2 2 0 Mu-like prophage protein Com DUF572 PF04502.13 CBY15743.1 - 2.9 7.4 14.9 3.7 7.1 14.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cupredoxin_1 PF13473.6 CBY15744.1 - 0.045 13.9 0.1 0.63 10.2 0.0 2.3 2 0 0 2 2 2 0 Cupredoxin-like domain DIOX_N PF14226.6 CBY15744.1 - 0.071 13.9 0.1 0.16 12.7 0.1 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal ODV-E18 PF10717.9 CBY15747.1 - 0.01 15.7 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2681 PF10883.8 CBY15747.1 - 0.073 13.5 0.2 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DAG1 PF05454.11 CBY15747.1 - 0.13 11.7 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) zf-TAZ PF02135.16 CBY15749.1 - 8.2e-18 64.6 21.0 1.2e-17 64.1 21.0 1.3 1 0 0 1 1 1 1 TAZ zinc finger HAT_KAT11 PF08214.11 CBY15750.1 - 1.3e-14 54.3 1.9 1.3e-14 54.3 1.9 3.4 2 2 1 3 3 3 1 Histone acetylation protein ZZ PF00569.17 CBY15750.1 - 3.8e-10 39.4 9.9 3.8e-10 39.4 9.9 3.4 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-TAZ PF02135.16 CBY15750.1 - 5.6e-10 39.5 29.1 5.6e-10 39.5 29.1 3.4 3 0 0 3 3 3 1 TAZ zinc finger PDZ PF00595.24 CBY15753.1 - 1.9e-42 143.5 8.8 2.7e-10 40.4 0.0 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 CBY15753.1 - 2.8e-30 103.9 1.0 4e-07 29.8 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 CBY15753.1 - 2.5e-21 75.8 6.1 1.3e-06 28.7 0.3 4.5 4 0 0 4 4 4 4 PDZ domain zf-RING_2 PF13639.6 CBY15753.1 - 2.3e-07 31.0 17.4 2.3e-07 31.0 17.4 2.8 4 0 0 4 4 3 1 Ring finger domain Tricorn_PDZ PF14685.6 CBY15753.1 - 8.3e-07 28.9 0.2 1.2 9.1 0.0 4.2 4 0 0 4 4 4 3 Tricorn protease PDZ domain zf-C3HC4 PF00097.25 CBY15753.1 - 1.7e-06 27.8 14.3 1.7e-06 27.8 14.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY15753.1 - 4.4e-06 26.4 19.0 4.4e-06 26.4 19.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY15753.1 - 6.4e-06 26.1 15.6 1.5e-05 24.9 15.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY15753.1 - 4.9e-05 23.1 13.4 4.9e-05 23.1 13.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY15753.1 - 0.002 18.0 15.5 0.002 18.0 15.5 2.4 3 0 0 3 3 2 1 zinc-RING finger domain zf-Nse PF11789.8 CBY15753.1 - 0.0028 17.4 10.8 0.0079 16.0 10.8 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CBY15753.1 - 0.0036 17.4 17.0 0.0036 17.4 17.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 CBY15753.1 - 0.097 12.9 0.8 0.75 10.0 0.1 2.4 2 0 0 2 2 2 0 U-box domain DUF1823 PF08853.11 CBY15753.1 - 0.15 12.2 0.4 0.34 11.1 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) Vac_ImportDeg PF09783.9 CBY15754.1 - 1.3e-54 184.4 1.6 1.5e-54 184.2 1.6 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein eRF1_1 PF03463.15 CBY15754.1 - 0.052 13.5 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 eRF1 domain 1 DEAD PF00270.29 CBY15755.1 - 3.2e-37 128.0 0.6 3.2e-37 128.0 0.6 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY15755.1 - 8.6e-18 64.7 0.1 1e-16 61.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY15755.1 - 0.00031 20.8 0.1 0.00031 20.8 0.1 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CBY15755.1 - 0.045 13.3 0.1 0.045 13.3 0.1 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 CBY15755.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.6 CBY15755.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MoaC PF01967.21 CBY15756.1 - 2.9e-41 140.8 0.1 3.1e-41 140.6 0.1 1.0 1 0 0 1 1 1 1 MoaC family MH1 PF03165.16 CBY15757.1 - 3e-11 43.4 0.3 5.2e-11 42.7 0.3 1.4 1 0 0 1 1 1 1 MH1 domain CTF_NFI PF00859.18 CBY15757.1 - 0.011 15.7 2.7 0.021 14.7 2.5 1.5 1 1 0 1 1 1 0 CTF/NF-I family transcription modulation region Use1 PF09753.9 CBY15760.1 - 0.63 9.7 3.0 0.8 9.4 3.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Cwf_Cwc_15 PF04889.12 CBY15760.1 - 0.66 9.7 5.7 0.79 9.4 5.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.9 CBY15760.1 - 4.4 5.7 13.7 4.8 5.6 13.7 1.1 1 0 0 1 1 1 0 Macoilin family VWD PF00094.25 CBY15762.1 - 2.8e-94 313.6 5.8 2.4e-30 105.9 0.1 4.9 4 0 0 4 4 4 4 von Willebrand factor type D domain C8 PF08742.11 CBY15762.1 - 1.9e-39 133.9 44.2 4.8e-19 68.5 13.4 9.9 9 2 2 11 11 11 3 C8 domain TIL PF01826.17 CBY15762.1 - 3.4e-26 91.2 82.4 3.2e-11 43.3 14.6 18.0 17 4 0 17 17 17 5 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.13 CBY15762.1 - 2.9e-07 30.1 42.3 2.6e-05 23.8 7.2 11.5 10 0 0 10 10 10 6 Pacifastin inhibitor (LCMII) VWC PF00093.18 CBY15762.1 - 0.0001 22.6 55.5 0.0008 19.7 9.1 17.9 11 6 5 16 16 16 5 von Willebrand factor type C domain Tubulin PF00091.25 CBY15763.1 - 4e-68 229.5 0.0 5.2e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY15763.1 - 1.8e-47 160.6 0.0 3e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY15763.1 - 0.0016 18.2 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain An_peroxidase PF03098.15 CBY15764.1 - 3.7e-26 91.8 0.0 4.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Trypsin PF00089.26 CBY15765.1 - 8.3e-47 159.8 1.3 1.3e-46 159.2 1.3 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY15765.1 - 5.4e-10 40.4 0.0 9.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain cEGF PF12662.7 CBY15765.1 - 8.2e-08 32.0 0.4 8.2e-08 32.0 0.4 2.9 3 0 0 3 3 3 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY15765.1 - 0.0001 22.5 6.0 0.0001 22.5 6.0 3.4 4 0 0 4 4 4 1 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY15765.1 - 0.0034 17.7 9.3 0.075 13.4 1.9 3.1 2 0 0 2 2 2 2 EGF-like domain Phage_holin_2_1 PF04971.12 CBY15765.1 - 0.15 12.1 1.3 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage P21 holin S EGF_3 PF12947.7 CBY15765.1 - 0.31 11.3 13.3 0.51 10.6 1.7 3.3 2 0 0 2 2 2 0 EGF domain EGF_CA PF07645.15 CBY15765.1 - 3.2 8.0 28.7 0.041 14.1 9.1 4.0 3 1 0 3 3 3 0 Calcium-binding EGF domain Ifi-6-16 PF06140.13 CBY15767.1 - 3e-10 39.9 23.5 5.2e-10 39.1 23.5 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family ParA PF10609.9 CBY15768.1 - 2.5e-90 302.3 0.2 2.8e-90 302.1 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBY15768.1 - 1.1e-10 41.6 0.1 1.9e-09 37.6 0.1 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 CBY15768.1 - 3.6e-07 29.7 0.0 5.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 CBY15768.1 - 8e-07 29.1 0.4 1.6e-05 24.9 0.4 2.6 2 1 0 2 2 2 1 AAA domain AAA_26 PF13500.6 CBY15768.1 - 3.5e-06 27.0 0.3 3.7e-05 23.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 CBY15768.1 - 0.0001 21.6 3.8 0.0017 17.6 0.6 2.6 1 1 2 3 3 3 1 Anion-transporting ATPase APS_kinase PF01583.20 CBY15768.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 CBY15768.1 - 0.12 12.2 0.1 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 CBY15768.1 - 0.13 11.8 0.6 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain LSM PF01423.22 CBY15769.1 - 4.7e-20 71.0 0.2 6.2e-20 70.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CBY15769.1 - 0.007 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 RimP C-terminal SH3 domain Sulfotransfer_2 PF03567.14 CBY15770.1 - 1.1e-26 94.3 0.0 1.8e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Med24_N PF11277.8 CBY15771.1 - 6.8e-40 137.0 13.2 3.3e-31 108.2 5.5 2.5 3 0 0 3 3 3 2 Mediator complex subunit 24 N-terminal Glyco_hydro_15 PF00723.21 CBY15772.1 - 2.3e-44 151.9 0.0 2.9e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 AMP-binding PF00501.28 CBY15773.1 - 1.2e-39 136.1 0.1 1.4e-39 135.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY15773.1 - 2.6e-16 60.4 0.1 5.2e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_Tnp_Tc5 PF03221.16 CBY15773.1 - 0.18 11.8 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Gal-3-0_sulfotr PF06990.11 CBY15774.1 - 2.7e-21 75.9 0.1 3.3e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Gal-3-0_sulfotr PF06990.11 CBY15775.1 - 1.6e-08 33.9 0.2 1.8e-08 33.7 0.2 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Mob1_phocein PF03637.17 CBY15776.1 - 1.5e-12 47.9 0.0 1.7e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family O-FucT PF10250.9 CBY15777.1 - 9.4e-14 51.8 0.1 1.2e-13 51.5 0.1 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HMG_box PF00505.19 CBY15780.1 - 3.1e-25 88.4 5.1 5.4e-25 87.6 5.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY15780.1 - 9.7e-12 45.3 3.1 2e-11 44.3 3.1 1.6 1 0 0 1 1 1 1 HMG-box domain RIB43A PF05914.12 CBY15780.1 - 0.0045 15.8 0.4 0.0045 15.8 0.4 1.4 2 0 0 2 2 2 1 RIB43A MlaC PF05494.12 CBY15780.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 MlaC protein SET PF00856.28 CBY15785.1 - 2.8e-17 63.6 0.2 1.9e-16 60.9 0.1 2.3 2 1 0 2 2 2 1 SET domain FYRC PF05965.14 CBY15785.1 - 3.3e-06 27.2 0.0 1e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus Glycos_transf_2 PF00535.26 CBY15786.1 - 1.5e-16 60.7 0.0 2.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBY15786.1 - 0.028 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Telomere_Sde2_2 PF13297.6 CBY15788.1 - 3.7e-22 77.7 0.4 3.7e-22 77.7 0.4 2.0 2 0 0 2 2 2 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 CBY15788.1 - 2.6e-11 43.6 1.3 2.6e-11 43.6 1.3 1.9 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Med22 PF06179.12 CBY15790.1 - 3.9e-23 81.7 3.6 4.8e-23 81.4 3.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Maf1 PF09174.10 CBY15790.1 - 0.014 15.6 1.3 0.017 15.3 1.3 1.1 1 0 0 1 1 1 0 Maf1 regulator Med11 PF10280.9 CBY15790.1 - 0.038 14.5 1.9 6.1 7.3 0.6 2.1 1 1 1 2 2 2 0 Mediator complex protein DZF PF07528.14 CBY15790.1 - 0.041 13.5 1.0 0.1 12.2 0.3 1.7 1 1 1 2 2 2 0 DZF domain CdvA PF18822.1 CBY15790.1 - 0.049 13.5 5.7 0.28 11.0 0.3 2.4 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Mod_r PF07200.13 CBY15790.1 - 0.082 13.0 4.3 0.11 12.5 4.3 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TBCC_N PF16752.5 CBY15790.1 - 0.13 12.7 5.9 0.2 12.1 5.9 1.4 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain YtxH PF12732.7 CBY15790.1 - 0.34 11.5 4.1 1.6 9.3 0.3 2.5 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.13 CBY15790.1 - 0.52 11.0 4.0 3.7 8.2 2.5 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FapA PF03961.13 CBY15790.1 - 0.62 8.6 6.5 2 7.0 1.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 CBY15790.1 - 0.72 9.8 6.8 0.84 9.6 1.6 2.5 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 CBY15790.1 - 1 9.5 6.1 3 8.0 6.1 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 CBY15790.1 - 2.9 7.7 6.7 14 5.5 0.9 2.5 2 1 0 2 2 2 0 Septum formation initiator Collagen PF01391.18 CBY15793.1 - 3.9e-08 32.9 14.6 6.5e-08 32.2 14.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PsbW PF07123.12 CBY15793.1 - 0.39 10.7 1.3 28 4.7 1.0 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) Glyco_hydro_67N PF03648.14 CBY15793.1 - 1.4 9.2 6.5 0.23 11.7 1.5 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus SNF PF00209.18 CBY15794.1 - 2.3e-107 359.9 16.3 1.7e-69 234.9 2.4 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family MWFE PF15879.5 CBY15794.1 - 1.2 9.3 3.0 11 6.3 0.1 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit DEAD PF00270.29 CBY15795.1 - 1.5e-44 151.8 0.0 1e-43 149.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY15795.1 - 5.3e-32 110.5 0.1 1e-31 109.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY15795.1 - 0.00018 21.5 0.0 0.00062 19.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY15795.1 - 0.00056 19.2 0.2 0.00085 18.6 0.2 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA PF00004.29 CBY15796.1 - 1.2e-24 87.2 0.0 9.6e-24 84.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3523 PF12037.8 CBY15796.1 - 8.1e-16 58.2 28.5 1.2e-15 57.6 28.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) RuvB_N PF05496.12 CBY15796.1 - 2.2e-07 30.7 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBY15796.1 - 0.0002 21.8 0.0 0.0002 21.8 0.0 3.3 2 2 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY15796.1 - 0.00025 21.3 3.2 0.055 13.7 0.0 2.9 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 CBY15796.1 - 0.00031 20.5 0.5 0.00091 19.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 CBY15796.1 - 0.00082 19.4 0.3 0.012 15.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBY15796.1 - 0.00087 18.7 0.0 0.0045 16.4 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBY15796.1 - 0.00088 19.6 0.0 0.0025 18.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Zot PF05707.12 CBY15796.1 - 0.00097 18.8 1.0 0.078 12.6 0.0 3.1 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_7 PF12775.7 CBY15796.1 - 0.0016 18.0 0.0 0.0038 16.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 CBY15796.1 - 0.0032 17.5 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 CBY15796.1 - 0.0043 17.2 0.0 0.016 15.3 0.0 2.1 1 0 0 1 1 1 1 Sigma-54 interaction domain Rad17 PF03215.15 CBY15796.1 - 0.0068 16.3 0.0 0.0068 16.3 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 CBY15796.1 - 0.01 15.6 0.3 0.031 14.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CBY15796.1 - 0.017 14.7 2.1 0.34 10.4 0.0 2.7 2 1 1 3 3 3 0 AAA domain TsaE PF02367.17 CBY15796.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CBY15796.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.9 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.6 CBY15796.1 - 0.23 12.0 0.0 0.23 12.0 0.0 2.7 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CBY15796.1 - 0.26 11.0 0.0 0.26 11.0 0.0 3.3 2 1 0 2 2 1 0 AAA domain DNA_pol3_delta2 PF13177.6 CBY15796.1 - 1.9 8.3 9.6 3.5 7.4 0.3 2.9 3 0 0 3 3 3 0 DNA polymerase III, delta subunit AAA_lid_3 PF17862.1 CBY15797.1 - 3.2e-05 23.7 0.2 4.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 AAA+ lid domain TRAM_LAG1_CLN8 PF03798.16 CBY15798.1 - 4.5e-33 114.7 20.4 6.9e-33 114.1 20.4 1.3 1 0 0 1 1 1 1 TLC domain TctB PF07331.11 CBY15798.1 - 0.091 13.0 7.0 0.075 13.3 1.3 2.8 2 2 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Phospholip_A2_1 PF00068.19 CBY15799.1 - 1.8e-14 54.1 5.2 1.8e-14 54.1 5.2 2.3 3 0 0 3 3 3 1 Phospholipase A2 Ras PF00071.22 CBY15800.1 - 7.8e-28 97.1 0.0 1e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY15800.1 - 2.5e-24 85.8 0.0 3.3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY15800.1 - 7e-05 22.3 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY15800.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane PF01061.24 CBY15801.1 - 1.7e-40 138.7 24.7 2.5e-40 138.2 24.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBY15801.1 - 3.6e-22 79.3 0.1 5.6e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CBY15801.1 - 7.6e-06 25.3 21.2 3.9e-05 22.9 19.2 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CBY15801.1 - 0.00016 21.6 1.0 0.00027 20.9 0.5 1.6 2 0 0 2 2 1 1 RsgA GTPase Dynamin_N PF00350.23 CBY15801.1 - 0.00055 20.0 0.5 0.0032 17.6 0.5 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBY15801.1 - 0.00075 19.6 1.0 0.0027 17.8 0.3 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CBY15801.1 - 0.00095 19.1 0.5 0.11 12.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CBY15801.1 - 0.00099 19.4 0.2 0.0049 17.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 CBY15801.1 - 0.0064 16.2 2.2 0.031 14.0 2.2 2.1 1 1 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 CBY15801.1 - 0.011 15.9 0.3 0.023 14.8 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 CBY15801.1 - 0.013 14.9 0.7 0.073 12.5 0.3 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY15801.1 - 0.014 15.8 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PDR_CDR PF06422.12 CBY15801.1 - 0.022 14.6 0.0 0.022 14.6 0.0 2.6 3 0 0 3 3 2 0 CDR ABC transporter MeaB PF03308.16 CBY15801.1 - 0.037 13.0 0.1 0.079 11.9 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IIGP PF05049.13 CBY15801.1 - 0.043 12.9 0.1 0.073 12.1 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_30 PF13604.6 CBY15801.1 - 0.053 13.2 0.0 0.13 12.0 0.1 1.7 2 0 0 2 2 1 0 AAA domain DUF3392 PF11872.8 CBY15801.1 - 0.056 13.7 0.4 0.056 13.7 0.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3392) AAA_24 PF13479.6 CBY15801.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CBY15801.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin PRK PF00485.18 CBY15801.1 - 0.076 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CBY15801.1 - 0.089 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CBY15801.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2368 PF10166.9 CBY15802.1 - 4e-33 113.9 0.8 4.2e-33 113.8 0.8 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) IMPa_helical PF18642.1 CBY15803.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease helical domain RhoGEF67_u1 PF16615.5 CBY15804.1 - 0.023 15.2 4.9 0.029 14.9 4.9 1.1 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 RabGAP-TBC PF00566.18 CBY15805.1 - 8.5e-48 162.8 0.4 1.8e-47 161.8 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain LRR_6 PF13516.6 CBY15806.1 - 6.6e-07 28.9 6.1 0.072 13.2 0.1 4.0 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 CBY15806.1 - 1e-06 29.0 7.9 0.0035 17.7 1.0 3.8 2 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY15806.1 - 0.033 13.9 7.5 0.039 13.7 2.5 3.0 1 1 2 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 CBY15806.1 - 0.14 12.8 4.8 24 6.0 0.2 4.9 3 2 0 3 3 3 0 Leucine Rich Repeat tRNA-synt_2 PF00152.20 CBY15807.1 - 1.8e-80 270.4 0.0 2.7e-80 269.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBY15807.1 - 1.2e-13 50.8 0.0 2.8e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBY15807.1 - 1.1e-08 34.9 0.0 0.00028 20.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Presenilin PF01080.17 CBY15807.1 - 8.5 5.0 7.2 12 4.6 7.2 1.2 1 0 0 1 1 1 0 Presenilin VWA_2 PF13519.6 CBY15808.1 - 7.3e-14 52.3 0.0 3.4e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CBY15808.1 - 0.0033 17.7 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4834 PF16118.5 CBY15809.1 - 0.02 15.8 1.7 1 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RNA_pol_Rpc4 PF05132.14 CBY15809.1 - 0.037 14.5 3.8 0.2 12.1 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Membralin PF09746.9 CBY15809.1 - 0.042 12.9 1.1 0.11 11.6 1.0 1.7 1 1 1 2 2 2 0 Tumour-associated protein YqfQ PF14181.6 CBY15809.1 - 1.4 9.1 12.7 1.3 9.2 4.9 2.2 2 0 0 2 2 2 0 YqfQ-like protein CPSF100_C PF13299.6 CBY15809.1 - 5.5 7.1 7.7 4.6 7.4 2.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2560 PF10834.8 CBY15811.1 - 0.021 15.0 0.1 0.033 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) ATG19_autophagy PF12744.7 CBY15812.1 - 0.0066 15.7 1.1 0.0066 15.7 1.1 1.9 2 0 0 2 2 2 1 Autophagy protein Atg19, Atg8-binding MukB PF04310.12 CBY15812.1 - 0.041 13.7 2.3 0.053 13.3 2.3 1.2 1 0 0 1 1 1 0 MukB N-terminal DUF5052 PF16475.5 CBY15812.1 - 0.21 11.2 3.6 0.092 12.4 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5052) DIT1_PvcA PF05141.12 CBY15812.1 - 0.26 10.7 6.1 0.32 10.4 6.1 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein BLI1 PF17324.2 CBY15812.1 - 0.3 11.8 15.6 0.59 10.8 4.5 2.6 1 1 1 2 2 2 0 BLOC-1 interactor 1 APG6_N PF17675.1 CBY15812.1 - 3.6 8.1 22.4 30 5.1 22.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region MerR-DNA-bind PF09278.11 CBY15812.1 - 3.7 8.1 7.3 0.42 11.2 0.3 2.7 3 1 0 3 3 3 0 MerR, DNA binding HIP1_clath_bdg PF16515.5 CBY15812.1 - 5.8 7.6 17.0 11 6.7 8.5 2.9 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1564 PF07600.11 CBY15812.1 - 6.3 6.5 10.2 4.1 7.1 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1564) Peptidase_C97 PF05903.14 CBY15813.1 - 3.6e-05 23.6 0.2 4.9e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain ComGF PF15980.5 CBY15813.1 - 0.0031 17.8 0.1 0.0051 17.1 0.1 1.3 1 0 0 1 1 1 1 Putative Competence protein ComGF PX PF00787.24 CBY15814.1 - 7.4e-14 51.7 2.3 7.4e-14 51.7 2.3 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CBY15814.1 - 0.045 13.3 24.4 0.22 11.1 18.5 3.2 2 1 0 2 2 2 0 Vps5 C terminal like CHGN PF05679.16 CBY15815.1 - 4e-24 85.3 1.2 4.2e-24 85.2 1.2 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY15815.1 - 1.2e-08 34.4 2.1 1.3e-08 34.4 1.3 1.4 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Pkinase PF00069.25 CBY15817.1 - 8.5e-44 149.9 0.0 9.7e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15817.1 - 3.8e-18 65.7 0.0 5.7e-18 65.1 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY15817.1 - 4.5e-06 25.7 0.0 5.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY15817.1 - 7.7e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY15817.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RUN PF02759.19 CBY15818.1 - 9.8e-11 41.8 1.7 2e-10 40.7 1.7 1.6 1 0 0 1 1 1 1 RUN domain HMG_box PF00505.19 CBY15818.1 - 0.024 15.0 0.1 0.08 13.4 0.1 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box Collagen PF01391.18 CBY15819.1 - 3e-19 68.5 60.0 5.7e-09 35.6 28.5 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY15819.1 - 7.4e-12 45.9 0.1 1.3e-11 45.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY15819.1 - 1.4e-05 25.7 0.0 3.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_11 PF13086.6 CBY15820.1 - 0.093 12.5 7.0 0.12 12.2 7.0 1.3 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 CBY15820.1 - 1.8 8.0 11.6 2.2 7.8 11.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 CBY15820.1 - 2.6 7.0 12.1 3 6.8 12.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Borrelia_P83 PF05262.11 CBY15820.1 - 4.9 5.5 22.1 5.9 5.3 22.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.16 CBY15820.1 - 5.3 7.0 6.9 6 6.9 6.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Trypsin PF00089.26 CBY15821.1 - 4.9e-24 85.4 0.5 5.6e-24 85.2 0.5 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY15821.1 - 0.031 15.2 0.0 0.08 13.8 0.0 1.7 1 1 0 1 1 1 0 Trypsin-like peptidase domain Amidase PF01425.21 CBY15822.1 - 2e-17 63.3 0.0 1e-16 60.9 0.0 1.8 1 1 0 1 1 1 1 Amidase MnmE_helical PF12631.7 CBY15824.1 - 0.039 14.1 1.0 0.051 13.7 1.0 1.2 1 0 0 1 1 1 0 MnmE helical domain SlyX PF04102.12 CBY15824.1 - 0.19 12.4 2.1 0.28 11.8 2.1 1.4 1 0 0 1 1 1 0 SlyX Lge1 PF11488.8 CBY15824.1 - 0.24 11.6 7.3 0.34 11.1 4.9 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF4110 PF13422.6 CBY15824.1 - 0.47 10.6 5.9 0.53 10.4 5.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) Caskin1-CID PF16600.5 CBY15825.1 - 2.8 8.6 6.6 1.4 9.5 1.7 2.0 1 1 1 2 2 2 0 Caskin1 CASK-interaction domain Kelch_2 PF07646.15 CBY15826.1 - 1.9e-05 24.4 0.3 0.94 9.6 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY15826.1 - 0.00093 19.1 1.4 0.13 12.3 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY15826.1 - 0.018 15.3 0.8 2.8 8.4 0.0 3.6 3 1 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY15826.1 - 0.063 13.3 0.5 17 5.5 0.0 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain HrpB1_HrpK PF09613.10 CBY15829.1 - 0.016 14.8 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Cluap1 PF10234.9 CBY15829.1 - 0.022 14.2 5.6 0.027 13.8 5.6 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Fib_alpha PF08702.10 CBY15829.1 - 0.066 13.4 3.7 0.85 9.8 4.1 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Trypsin PF00089.26 CBY15830.1 - 8.6e-12 45.3 0.1 1.4e-11 44.7 0.1 1.3 1 0 0 1 1 1 1 Trypsin Phage_holin_2_2 PF10746.9 CBY15831.1 - 0.095 12.4 0.1 0.91 9.2 0.0 2.0 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II FAD_binding_4 PF01565.23 CBY15835.1 - 6e-13 48.7 0.0 9.7e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain RINGv PF12906.7 CBY15837.1 - 7.8 6.7 8.6 3 8.0 1.6 2.6 2 0 0 2 2 2 0 RING-variant domain Pkinase PF00069.25 CBY15838.1 - 1e-23 84.1 0.0 2.9e-23 82.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15838.1 - 5.4e-09 35.7 0.0 8.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB1 PF18190.1 CBY15838.1 - 6.4e-09 36.0 0.1 1.1e-07 32.0 0.1 2.3 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 1 Plk4_PB2 PF18409.1 CBY15838.1 - 0.00041 21.0 0.0 0.0019 18.9 0.0 2.1 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 2 Polo_box_3 PF18544.1 CBY15838.1 - 0.016 15.8 0.0 0.039 14.6 0.0 1.6 1 0 0 1 1 1 0 Polo box domain ECH_1 PF00378.20 CBY15840.1 - 5.5e-30 104.5 0.1 1e-29 103.6 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY15840.1 - 1.4e-17 64.2 0.0 1.6e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase IMD PF08397.11 CBY15841.1 - 2.2 7.6 12.7 2.3 7.6 12.7 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain Multi_Drug_Res PF00893.19 CBY15842.1 - 0.085 13.5 1.7 0.13 13.0 1.7 1.4 1 0 0 1 1 1 0 Small Multidrug Resistance protein DUF5372 PF17342.2 CBY15842.1 - 0.16 12.4 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5372) AAA_6 PF12774.7 CBY15843.1 - 7.5e-117 390.0 0.9 8.7e-116 386.5 0.0 3.1 4 0 0 4 4 3 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CBY15843.1 - 9.2e-62 208.7 0.3 2e-60 204.3 0.0 3.2 3 1 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBY15843.1 - 2.3e-54 183.9 0.0 2.3e-54 183.9 0.0 4.7 5 1 1 6 6 5 1 ATP-binding dynein motor region Dynein_C PF18199.1 CBY15843.1 - 6.2e-44 150.5 0.7 2.2e-43 148.7 0.7 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CBY15843.1 - 1.3e-43 148.7 0.0 5.7e-36 123.7 0.0 5.3 5 0 0 5 5 5 2 P-loop containing dynein motor region MT PF12777.7 CBY15843.1 - 6.5e-42 143.8 9.0 1.1e-41 143.1 9.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBY15843.1 - 3.7e-36 124.2 0.0 8.2e-15 55.0 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 CBY15843.1 - 1.9e-33 115.6 0.0 4.7e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBY15843.1 - 2.2e-32 111.7 0.0 1.6e-31 108.9 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CBY15843.1 - 6.6e-15 55.6 1.0 0.017 15.4 0.0 7.0 7 0 0 7 7 7 3 AAA domain AAA PF00004.29 CBY15843.1 - 3.7e-14 53.3 0.0 0.011 16.1 0.0 5.8 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBY15843.1 - 4.4e-12 46.7 0.9 0.0096 16.5 0.0 5.8 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.6 CBY15843.1 - 1.8e-11 44.3 0.0 0.0042 17.2 0.0 4.9 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 CBY15843.1 - 2.3e-10 41.1 0.0 1 9.8 0.0 6.4 5 0 0 5 5 5 2 AAA ATPase domain T2SSE PF00437.20 CBY15843.1 - 3.2e-07 29.7 0.0 0.1 11.6 0.0 3.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_lid_1 PF17857.1 CBY15843.1 - 8.3e-07 29.2 0.2 0.00035 20.7 0.0 3.9 3 0 0 3 3 3 1 AAA+ lid domain AAA_29 PF13555.6 CBY15843.1 - 1.1e-06 28.3 0.0 0.13 12.0 0.0 3.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CBY15843.1 - 1.3e-06 27.9 0.0 0.058 12.7 0.0 3.2 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_28 PF13521.6 CBY15843.1 - 2.2e-06 28.0 0.0 0.69 10.1 0.0 4.7 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 CBY15843.1 - 2.8e-06 26.9 3.7 0.86 8.9 0.0 4.9 6 0 0 6 6 5 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CBY15843.1 - 1.8e-05 25.1 0.5 0.21 11.9 0.0 4.9 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.22 CBY15843.1 - 2e-05 24.9 0.0 5 7.6 0.0 4.9 4 0 0 4 4 4 0 RNA helicase AAA_24 PF13479.6 CBY15843.1 - 3.2e-05 23.8 2.4 5.1 6.8 0.0 5.0 5 0 0 5 5 4 0 AAA domain IstB_IS21 PF01695.17 CBY15843.1 - 3.9e-05 23.5 0.5 0.093 12.5 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_30 PF13604.6 CBY15843.1 - 4.4e-05 23.3 0.4 13 5.4 0.1 4.5 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 CBY15843.1 - 0.00036 20.2 0.2 0.22 11.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 CBY15843.1 - 0.00086 18.3 0.4 5.5 5.8 0.0 4.1 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 CBY15843.1 - 0.0015 19.0 5.4 2.9 8.4 0.0 4.6 5 0 0 5 5 3 1 ABC transporter BRE1 PF08647.11 CBY15843.1 - 0.0064 16.5 4.5 0.0064 16.5 4.5 4.7 4 1 0 4 4 3 1 BRE1 E3 ubiquitin ligase NACHT PF05729.12 CBY15843.1 - 0.0084 16.0 3.7 28 4.6 0.1 4.9 5 0 0 5 5 4 0 NACHT domain TsaE PF02367.17 CBY15843.1 - 0.0087 16.1 1.7 6.6 6.8 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CBY15843.1 - 0.013 15.6 0.0 8.7 6.3 0.0 3.9 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 CBY15843.1 - 0.039 13.7 0.7 1.4 8.6 0.0 3.6 4 0 0 4 4 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_21 PF13304.6 CBY15843.1 - 0.042 13.7 0.1 8.8 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBY15843.1 - 0.063 13.8 18.9 9.3 6.7 0.0 6.6 6 0 0 6 6 6 0 AAA domain PduV-EutP PF10662.9 CBY15843.1 - 0.078 12.7 0.2 3.8 7.3 0.1 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation E2R135 PF11570.8 CBY15843.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.2 3 1 0 3 3 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Nairo_nucleo PF02477.15 CBY15843.1 - 1.5 7.5 7.9 0.16 10.8 0.1 2.2 2 0 0 2 2 2 0 Nucleocapsid N protein Pkinase PF00069.25 CBY15845.1 - 2.7e-70 236.7 0.0 4.2e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15845.1 - 5.9e-34 117.5 0.0 2.2e-33 115.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY15845.1 - 0.00052 19.4 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY15845.1 - 0.0018 17.7 0.2 0.0018 17.7 0.2 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY15845.1 - 0.0059 16.5 0.9 2.6 7.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY15845.1 - 0.044 12.7 0.3 0.13 11.2 0.1 2.0 2 1 0 2 2 2 0 Haspin like kinase domain MCPVI PF02993.14 CBY15845.1 - 0.083 12.7 3.0 0.13 12.0 3.0 1.2 1 0 0 1 1 1 0 Minor capsid protein VI TERB2 PF15101.6 CBY15845.1 - 0.086 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CTNNB1_binding PF08347.11 CBY15845.1 - 0.36 11.0 3.4 0.66 10.1 3.4 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding NAGidase PF07555.13 CBY15847.1 - 8e-79 265.0 0.0 1.7e-78 263.9 0.0 1.5 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase PDCD9 PF07147.12 CBY15848.1 - 3.5e-30 105.6 0.2 2.5e-21 76.4 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S30 (PDCD9) EF-1_beta_acid PF10587.9 CBY15849.1 - 3e-14 53.2 5.8 3e-14 53.2 5.8 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region EF1_GNE PF00736.19 CBY15849.1 - 3e-11 43.3 0.5 5e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain Cwf_Cwc_15 PF04889.12 CBY15849.1 - 0.0047 16.7 3.0 0.0058 16.4 3.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 CBY15850.1 - 0.0086 16.9 0.0 0.41 11.6 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY15850.1 - 0.075 13.3 0.0 13 6.1 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Itfg2 PF15907.5 CBY15850.1 - 0.081 12.0 0.1 0.24 10.4 0.0 1.7 1 1 1 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Cadherin_C PF01049.17 CBY15851.1 - 2.9e-12 47.1 0.4 3.9e-12 46.7 0.4 1.2 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin PF00028.17 CBY15852.1 - 2e-08 34.6 0.0 6.3e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Cadherin domain Adeno_E3_CR2 PF02439.15 CBY15852.1 - 0.042 13.6 0.4 0.085 12.6 0.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LapA_dom PF06305.11 CBY15852.1 - 0.09 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4448 PF14610.6 CBY15852.1 - 0.14 11.9 0.5 0.43 10.3 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF898 PF05987.13 CBY15852.1 - 0.16 11.0 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Myotub-related PF06602.14 CBY15853.1 - 6.5e-47 160.2 1.0 8.3e-47 159.8 1.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FDX-ACB PF03147.14 CBY15854.1 - 0.029 14.8 0.1 0.17 12.3 0.0 2.4 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain RVT_1 PF00078.27 CBY15855.1 - 7.4e-24 84.5 0.0 1.5e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C48 PF02902.19 CBY15857.1 - 7.8e-11 42.2 4.9 7.4e-05 22.7 1.7 2.6 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain IRK_C PF17655.1 CBY15863.1 - 1.5e-67 226.5 0.0 2.1e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain CUB PF00431.20 CBY15864.1 - 6.6e-08 32.9 0.2 1e-07 32.3 0.2 1.3 1 0 0 1 1 1 1 CUB domain RicinB_lectin_2 PF14200.6 CBY15865.1 - 3.9e-05 24.3 4.5 5.7e-05 23.8 2.9 2.1 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like PG_binding_1 PF01471.18 CBY15867.1 - 2.3e-05 24.5 0.1 1.6 9.0 0.0 3.9 4 0 0 4 4 4 2 Putative peptidoglycan binding domain Ribosomal_S18 PF01084.20 CBY15867.1 - 0.0018 18.5 0.0 0.15 12.3 0.0 3.1 2 0 0 2 2 2 1 Ribosomal protein S18 PG_binding_2 PF08823.11 CBY15867.1 - 0.0066 16.7 0.0 43 4.5 0.0 4.2 3 1 1 4 4 4 1 Putative peptidoglycan binding domain RNA_pol_Rpb1_1 PF04997.12 CBY15868.1 - 2.7e-96 322.6 0.0 4e-96 322.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CBY15868.1 - 8.6e-75 250.5 0.1 1.5e-74 249.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CBY15868.1 - 1.6e-09 37.9 0.1 3.3e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 DUF5480 PF17576.2 CBY15870.1 - 0.013 15.5 2.2 0.013 15.5 2.2 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5480) CLZ PF16526.5 CBY15871.1 - 0.14 12.5 1.2 0.38 11.1 0.4 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels tRNA-synt_2b PF00587.25 CBY15872.1 - 1.7e-22 80.2 0.0 4.1e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 CBY15872.1 - 1.2e-10 41.3 0.0 2.7e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3958 PF13125.6 CBY15873.1 - 0.011 16.0 0.8 0.015 15.5 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) SPT16 PF08644.11 CBY15873.1 - 0.057 13.6 2.2 0.076 13.2 2.2 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) SPT2 PF08243.11 CBY15873.1 - 0.76 10.3 6.4 27 5.3 6.4 2.0 1 1 0 1 1 1 0 SPT2 chromatin protein dCMP_cyt_deam_1 PF00383.23 CBY15877.1 - 4e-14 52.3 0.1 7e-14 51.5 0.0 1.4 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBY15877.1 - 7.5e-07 29.4 0.1 1e-06 29.0 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glycos_transf_2 PF00535.26 CBY15878.1 - 2.8e-05 24.0 0.0 7.2e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 COPIIcoated_ERV PF07970.12 CBY15879.1 - 7.2e-37 127.4 1.0 1e-36 126.8 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBY15879.1 - 4.9e-27 94.1 0.5 1.6e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 CBY15881.1 - 1.4e-07 31.1 0.0 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15881.1 - 0.0045 16.3 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Gal-3-0_sulfotr PF06990.11 CBY15882.1 - 8.8e-32 110.5 0.1 9.7e-32 110.3 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_3 PF13469.6 CBY15882.1 - 0.00047 20.6 0.0 0.00061 20.2 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase family DUF3450 PF11932.8 CBY15883.1 - 2.9e-05 23.5 6.3 3.6e-05 23.2 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) SCP-1 PF05483.12 CBY15883.1 - 0.00012 20.2 5.5 0.00014 20.1 5.5 1.0 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) HTH_Tnp_IS630 PF01710.16 CBY15883.1 - 0.00042 20.4 2.4 0.00058 19.9 2.4 1.2 1 0 0 1 1 1 1 Transposase Mit_ribos_Mrp51 PF11709.8 CBY15883.1 - 0.00073 19.2 2.0 0.0008 19.1 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Wtap PF17098.5 CBY15883.1 - 0.012 15.5 3.3 0.015 15.3 3.3 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family NYD-SP28_assoc PF14775.6 CBY15883.1 - 0.018 15.2 8.0 0.36 11.0 1.3 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain ERM PF00769.19 CBY15883.1 - 0.025 14.4 7.7 0.031 14.1 7.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family JAKMIP_CC3 PF16034.5 CBY15883.1 - 0.04 13.9 10.6 0.07 13.1 10.6 1.6 1 1 0 1 1 1 0 JAKMIP CC3 domain TSC22 PF01166.18 CBY15883.1 - 0.063 13.6 2.0 0.063 13.6 2.0 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family HEPN_SAV2148 PF18725.1 CBY15883.1 - 0.086 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 SAV2148-like HEPN YabA PF06156.13 CBY15883.1 - 0.12 13.1 11.1 1.7 9.3 6.5 2.1 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 CBY15883.1 - 0.18 12.2 15.4 1.1 9.7 8.4 2.3 1 1 1 2 2 2 0 Cell division protein ZapB CENP-F_N PF10481.9 CBY15883.1 - 0.21 11.2 8.6 0.29 10.7 8.6 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain Ax_dynein_light PF10211.9 CBY15883.1 - 0.35 10.8 10.0 0.44 10.5 9.4 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain Cep57_MT_bd PF06657.13 CBY15883.1 - 0.46 11.0 5.7 2.1 8.9 0.4 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 CBY15883.1 - 0.77 9.6 12.2 0.38 10.5 4.6 2.3 1 1 2 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 CBY15883.1 - 1.4 9.1 12.6 0.89 9.7 1.8 2.4 1 1 1 2 2 2 0 bZIP transcription factor Herpes_BLRF2 PF05812.12 CBY15883.1 - 2.2 8.4 7.6 1.4 9.1 0.7 2.6 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein APG6_N PF17675.1 CBY15883.1 - 2.5 8.7 10.8 9.4 6.8 10.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 CBY15883.1 - 4.8 7.3 9.7 1.1 9.4 3.9 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation FlaC_arch PF05377.11 CBY15883.1 - 4.8 7.7 13.0 2.2 8.7 4.1 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4537 PF15057.6 CBY15884.1 - 5.1e-31 107.2 0.0 6.3e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 CBY15884.1 - 0.00029 20.6 0.2 0.11 12.4 0.0 2.1 2 0 0 2 2 2 2 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 CBY15884.1 - 0.0013 18.4 0.1 0.0028 17.3 0.0 1.5 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain Hyccin PF09790.9 CBY15886.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Hyccin FA_hydroxylase PF04116.13 CBY15887.1 - 4.7e-13 49.6 1.2 8e-13 48.9 1.2 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Glyco_transf_10 PF00852.19 CBY15889.1 - 6.7e-12 45.5 0.1 1.5e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY15889.1 - 8.4e-12 45.5 0.0 1.7e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal CIMR PF00878.18 CBY15890.1 - 0.0002 21.5 0.1 0.00026 21.1 0.1 1.2 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 CBY15890.1 - 0.0077 16.1 0.6 0.0098 15.8 0.6 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 14-3-3 PF00244.20 CBY15891.1 - 4.2e-107 356.7 2.6 4.8e-107 356.5 2.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Kelch_1 PF01344.25 CBY15892.1 - 0.039 13.6 0.6 1 9.0 0.0 2.7 2 1 0 2 2 2 0 Kelch motif TPD52 PF04201.15 CBY15894.1 - 5.7e-20 71.6 0.2 6.7e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 Tumour protein D52 family DUF4617 PF15395.6 CBY15895.1 - 0.2 9.9 0.0 0.21 9.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) fn3_4 PF16794.5 CBY15896.1 - 9.6e-28 96.1 0.0 1.8e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin-III type domain ATG16 PF08614.11 CBY15896.1 - 0.0056 16.9 8.9 0.0056 16.9 8.9 2.4 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) LTXXQ PF07813.12 CBY15896.1 - 0.1 13.4 2.6 0.16 12.7 1.3 2.1 1 1 1 2 2 2 0 LTXXQ motif family protein DUF1043 PF06295.12 CBY15896.1 - 0.27 11.2 7.5 0.91 9.5 7.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) UPF0242 PF06785.11 CBY15896.1 - 0.45 10.6 14.7 0.039 14.1 9.4 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4047 PF13256.6 CBY15896.1 - 0.65 10.2 9.3 0.095 12.9 4.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) APG6_N PF17675.1 CBY15896.1 - 3.9 8.0 20.2 0.23 12.0 3.8 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 CBY15896.1 - 9.3 5.5 10.8 0.61 9.4 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Ammonium_transp PF00909.21 CBY15897.1 - 3.9e-66 223.4 25.3 5.5e-66 222.9 25.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family ApbA_C PF08546.11 CBY15897.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Lyase_1 PF00206.20 CBY15898.1 - 1.2e-56 192.4 0.0 4.8e-45 154.3 0.0 2.1 1 1 1 2 2 2 2 Lyase ssDBP_DBD PF18361.1 CBY15899.1 - 0.019 15.1 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Cep57_CLD PF14073.6 CBY15899.1 - 0.03 14.4 5.5 0.03 14.4 5.5 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DUF4085 PF13315.6 CBY15899.1 - 0.049 13.3 7.4 1.6 8.3 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4085) CemA PF03040.14 CBY15899.1 - 0.12 12.3 2.5 0.16 11.9 2.5 1.2 1 0 0 1 1 1 0 CemA family Mis12 PF05859.12 CBY15899.1 - 0.22 11.6 3.5 3.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Mis12 protein TMCO5 PF14992.6 CBY15899.1 - 0.27 10.8 11.8 0.38 10.3 11.8 1.3 1 0 0 1 1 1 0 TMCO5 family Lzipper-MIP1 PF14389.6 CBY15899.1 - 0.3 11.4 10.1 2.7 8.3 2.5 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MADF_DNA_bdg PF10545.9 CBY15899.1 - 0.54 10.6 8.1 0.067 13.5 1.9 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3899 PF13038.6 CBY15899.1 - 0.54 10.8 2.3 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Myb_DNA-bind_4 PF13837.6 CBY15899.1 - 0.56 10.6 11.8 0.094 13.1 4.5 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain CREPT PF16566.5 CBY15899.1 - 0.91 9.7 12.0 1.7 8.8 11.5 1.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FAM184 PF15665.5 CBY15899.1 - 1 9.1 13.6 2 8.1 13.6 1.3 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF16 PF01519.16 CBY15899.1 - 6 7.4 9.9 0.86 10.1 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Homeodomain PF00046.29 CBY15900.1 - 8.9e-24 83.1 9.2 4.3e-10 39.3 2.5 3.3 3 0 0 3 3 3 3 Homeodomain YdaS_antitoxin PF15943.5 CBY15900.1 - 0.00023 21.0 0.7 0.13 12.1 0.0 3.4 4 0 0 4 4 4 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Thioredoxin_11 PF18078.1 CBY15900.1 - 0.047 13.8 0.2 0.047 13.8 0.2 2.3 1 1 1 2 2 2 0 Thioredoxin-like SNTX domain DUP PF00674.18 CBY15900.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 DUP family Homeobox_KN PF05920.11 CBY15900.1 - 0.43 10.5 2.6 10 6.1 0.5 3.1 3 0 0 3 3 3 0 Homeobox KN domain Phage_holin_2_4 PF16082.5 CBY15900.1 - 6.2 6.6 8.0 4.5 7.1 0.8 3.0 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like V-set PF07686.17 CBY15902.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain Ig_2 PF13895.6 CBY15902.1 - 0.011 16.1 0.1 0.018 15.3 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 CBY15902.1 - 0.12 12.9 0.1 0.22 12.1 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin domain adh_short_C2 PF13561.6 CBY15903.1 - 4.1e-56 190.2 1.1 4.7e-56 190.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY15903.1 - 3.3e-51 173.5 0.6 4.3e-51 173.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY15903.1 - 5.5e-16 59.0 0.7 2.8e-15 56.7 0.2 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 CBY15903.1 - 3.1e-05 23.5 0.2 6.7e-05 22.5 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBY15903.1 - 0.00071 18.8 0.0 0.00093 18.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 CBY15903.1 - 0.0046 16.9 1.4 0.016 15.1 0.1 2.3 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CBY15903.1 - 0.0047 17.1 0.1 3.6 7.8 0.0 2.4 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CBY15903.1 - 0.012 15.6 0.3 0.027 14.5 0.3 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 CBY15903.1 - 0.055 13.0 0.3 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family Glyco_hydro38C2 PF17677.1 CBY15904.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF902 PF06001.13 CBY15905.1 - 2.3e-17 63.2 7.3 6e-17 61.8 7.3 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.25 CBY15905.1 - 2.1e-10 40.5 0.1 5.9e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 CBY15905.1 - 0.029 14.3 4.6 0.029 14.3 4.6 2.8 2 1 0 2 2 2 0 PHD-finger TRM PF02005.16 CBY15905.1 - 0.061 12.5 0.3 0.087 12.0 0.3 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Gla PF00594.20 CBY15907.1 - 1e-10 41.6 4.7 1e-10 41.6 4.7 1.7 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain HflK_N PF12221.8 CBY15907.1 - 0.071 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial membrane protein N terminal RVT_1 PF00078.27 CBY15909.1 - 2.6e-27 95.8 0.0 4.4e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3216 PF11505.8 CBY15910.1 - 0.0088 16.2 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3216) DUF1489 PF07370.11 CBY15910.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) AROS PF15684.5 CBY15910.1 - 0.27 11.8 1.4 0.66 10.6 1.4 1.6 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 DUF5106 PF17127.4 CBY15911.1 - 0.094 13.0 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Homeobox_KN PF05920.11 CBY15912.1 - 1.4e-07 31.3 0.6 2e-07 30.8 0.6 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY15912.1 - 0.0044 16.8 0.4 0.0059 16.4 0.4 1.2 1 0 0 1 1 1 1 Homeodomain MIP PF00230.20 CBY15913.1 - 1.5e-05 24.8 1.4 2.1e-05 24.4 1.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein DuoxA PF10204.9 CBY15913.1 - 0.13 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor Kelch_1 PF01344.25 CBY15914.1 - 0.0092 15.5 0.2 0.63 9.7 0.0 2.9 2 1 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CBY15914.1 - 0.057 13.7 0.1 8.5 6.8 0.1 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain HSP20 PF00011.21 CBY15915.1 - 1.5e-09 37.9 0.5 2.1e-09 37.4 0.5 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family UNC-93 PF05978.16 CBY15916.1 - 2e-09 37.4 11.4 2e-09 37.4 11.4 3.4 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CBY15916.1 - 2e-06 27.0 13.5 2e-06 27.0 13.5 3.0 2 2 0 3 3 3 2 Major Facilitator Superfamily YtpI PF14007.6 CBY15916.1 - 1.8 8.7 13.3 0.33 11.1 0.2 4.3 4 0 0 4 4 4 0 YtpI-like protein DUF1158 PF06643.11 CBY15916.1 - 2.5 8.7 8.8 2.9 8.5 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1158) Nudix_hydro PF18290.1 CBY15917.1 - 3.4e-23 81.4 0.2 7.1e-23 80.4 0.2 1.6 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 CBY15917.1 - 2.5e-20 72.8 0.0 5.2e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Trypsin PF00089.26 CBY15920.1 - 2.1e-36 125.8 0.1 1.7e-29 103.3 0.1 2.1 1 1 1 2 2 2 2 Trypsin DUF316 PF03761.15 CBY15920.1 - 0.0027 17.3 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 Trypsin_2 PF13365.6 CBY15920.1 - 0.081 13.8 0.0 0.11 13.4 0.0 1.3 1 0 0 1 1 1 0 Trypsin-like peptidase domain bZIP_1 PF00170.21 CBY15921.1 - 5.7e-09 35.9 14.8 1.1e-08 35.0 14.4 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CBY15921.1 - 4e-06 27.2 10.7 8.4e-06 26.2 10.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CBY15921.1 - 1.2e-05 25.3 12.8 6.4e-05 23.0 12.3 2.3 1 1 1 2 2 2 1 Basic region leucine zipper Cas_Csn2 PF09711.10 CBY15921.1 - 0.025 14.3 3.7 0.53 9.9 0.9 2.3 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csn2) PDZ PF00595.24 CBY15923.1 - 4.1e-106 347.5 4.5 5.5e-14 52.3 0.0 9.4 9 0 0 9 9 9 9 PDZ domain PDZ_6 PF17820.1 CBY15923.1 - 1.1e-100 329.3 18.8 1.8e-15 56.5 0.1 9.5 9 0 0 9 9 9 9 PDZ domain PDZ_2 PF13180.6 CBY15923.1 - 1.9e-55 185.1 7.0 8.3e-07 29.3 0.0 9.5 9 0 0 9 9 9 9 PDZ domain Urocanase_N PF17391.2 CBY15923.1 - 2.1e-51 172.9 0.3 4.4e-51 171.9 0.3 1.6 1 0 0 1 1 1 1 Urocanase N-terminal domain Urocanase PF01175.18 CBY15923.1 - 4e-34 118.1 0.1 9.6e-34 116.9 0.1 1.6 1 0 0 1 1 1 1 Urocanase Rossmann-like domain DUF3394 PF11874.8 CBY15923.1 - 1.8e-09 37.6 0.0 3.3 7.4 0.0 7.2 6 2 0 7 7 7 3 Domain of unknown function (DUF3394) Tetraspanin PF00335.20 CBY15923.1 - 5.7e-06 26.2 1.7 5.7e-06 26.2 1.7 1.8 2 0 0 2 2 2 1 Tetraspanin family CDC45 PF02724.14 CBY15923.1 - 7.1 4.8 16.8 11 4.1 16.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Guanylate_kin PF00625.21 CBY15924.1 - 1.9e-42 145.0 0.6 1.9e-42 145.0 0.6 1.6 2 0 0 2 2 2 1 Guanylate kinase SH3_2 PF07653.17 CBY15924.1 - 2.6e-05 23.8 0.0 6.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY15924.1 - 0.0026 17.4 0.0 0.0083 15.7 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SUFU_C PF12470.8 CBY15924.1 - 0.058 13.4 0.1 0.093 12.8 0.1 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Peptidase_S49_N PF08496.10 CBY15924.1 - 6.4 6.8 7.8 14 5.7 7.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.25 CBY15926.1 - 7.5e-09 35.3 0.0 2.5e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15926.1 - 0.011 15.1 0.0 0.047 13.0 0.0 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase Peptidase_C1_2 PF03051.15 CBY15926.1 - 0.053 12.3 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C1-like family Sof1 PF04158.14 CBY15927.1 - 9.2e-30 102.8 6.7 1e-29 102.6 6.7 1.0 1 0 0 1 1 1 1 Sof1-like domain MAP65_ASE1 PF03999.12 CBY15929.1 - 0.1 11.3 14.3 0.11 11.2 14.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Gaa1 PF04114.14 CBY15929.1 - 0.18 10.8 2.2 0.23 10.4 2.2 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component NUDE_C PF04880.13 CBY15929.1 - 0.55 10.7 15.6 0.85 10.1 15.6 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Otopetrin PF03189.13 CBY15929.1 - 1.1 8.0 4.8 1.3 7.8 4.8 1.2 1 0 0 1 1 1 0 Otopetrin Mucin PF01456.17 CBY15929.1 - 1.1 9.2 64.5 3.3 7.7 64.2 1.9 1 1 0 1 1 1 0 Mucin-like glycoprotein TFIIA PF03153.13 CBY15929.1 - 2 8.3 9.5 2.3 8.1 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CBY15929.1 - 3.3 8.3 15.9 5.3 7.7 15.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.13 CBY15929.1 - 4.7 5.4 7.6 6.1 5.1 7.6 1.2 1 0 0 1 1 1 0 Menin DUF4551 PF15087.6 CBY15929.1 - 6.7 5.4 8.4 7.5 5.3 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DnaJ PF00226.31 CBY15930.1 - 5.6e-16 58.4 0.0 1.7e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain RB_A PF01858.17 CBY15930.1 - 0.026 14.4 2.2 0.051 13.4 2.2 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain WXG100 PF06013.12 CBY15933.1 - 0.015 15.5 5.3 0.1 12.9 0.9 3.3 1 1 0 2 2 2 0 Proteins of 100 residues with WXG COMMD1_N PF17221.3 CBY15933.1 - 0.86 9.9 8.7 0.59 10.5 3.2 2.6 1 1 2 3 3 3 0 COMMD1 N-terminal domain DUF4201 PF13870.6 CBY15933.1 - 1.1 9.0 35.7 0.035 13.8 22.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ERM PF00769.19 CBY15933.1 - 1.7 8.4 41.5 6.6 6.5 7.8 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Fez1 PF06818.15 CBY15933.1 - 4 7.9 40.0 0.12 12.8 15.5 2.8 1 1 1 2 2 2 0 Fez1 DUF745 PF05335.13 CBY15933.1 - 5.2 6.8 18.5 0.46 10.2 6.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF1192 PF06698.11 CBY15933.1 - 7.1 6.8 11.0 1.7 8.7 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) HrpB7 PF09486.10 CBY15933.1 - 9.3 6.6 15.3 0.18 12.2 2.5 3.1 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) KRTDAP PF15200.6 CBY15934.1 - 0.013 15.2 0.1 0.057 13.2 0.1 2.1 1 1 0 1 1 1 0 Keratinocyte differentiation-associated DUF4201 PF13870.6 CBY15934.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) RabGAP-TBC PF00566.18 CBY15935.1 - 1.1e-11 44.8 0.2 2.5e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Inositol_P PF00459.25 CBY15936.1 - 4.7e-70 236.2 0.0 5.3e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RNB PF00773.19 CBY15937.1 - 2.1e-95 319.8 0.0 3.5e-95 319.1 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.11 CBY15937.1 - 0.00025 20.6 0.1 0.00059 19.5 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain CSD2 PF17876.1 CBY15937.1 - 0.0011 19.1 0.1 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 Cold shock domain Dis3l2_C_term PF17877.1 CBY15937.1 - 0.0049 17.2 0.4 0.085 13.2 0.1 2.6 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 CBY15937.1 - 0.027 14.5 0.1 0.26 11.3 0.0 2.6 2 0 0 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) Gemini_AC4_5 PF04807.12 CBY15937.1 - 0.085 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Elong_Iki1 PF10483.9 CBY15938.1 - 0.03 13.8 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF4830 PF16112.5 CBY15938.1 - 0.046 14.2 0.1 0.067 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4830) CoaE PF01121.20 CBY15939.1 - 3.1e-35 121.4 0.0 4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 CBY15939.1 - 3e-06 27.5 0.0 4.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY15939.1 - 8.3e-05 23.1 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBY15939.1 - 0.0083 15.4 0.4 1.7 7.9 0.0 2.8 2 1 0 2 2 2 2 Zeta toxin PRK PF00485.18 CBY15939.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family dNK PF01712.19 CBY15939.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.6 1 1 1 2 2 2 0 Deoxynucleoside kinase Kelch_2 PF07646.15 CBY15940.1 - 5.8e-05 22.9 0.1 1.9 8.6 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY15940.1 - 0.0066 16.4 2.2 0.054 13.5 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY15940.1 - 0.16 12.3 2.1 2.8 8.4 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Collagen PF01391.18 CBY15941.1 - 1.5e-07 31.1 19.6 2.4e-07 30.4 19.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ubiquitin PF00240.23 CBY15942.1 - 0.0014 18.3 0.0 0.0041 16.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family VWA PF00092.28 CBY15943.1 - 1e-12 48.7 0.1 1.5e-07 31.8 0.0 3.7 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 CBY15943.1 - 2.5e-07 31.3 1.8 0.05 14.3 0.0 4.0 4 1 0 4 4 4 2 von Willebrand factor type A domain IPK PF03770.16 CBY15947.1 - 0.021 14.7 2.2 0.021 14.7 2.2 2.0 2 1 0 2 2 2 0 Inositol polyphosphate kinase ssDBP_DBD PF18361.1 CBY15947.1 - 0.091 12.9 0.3 0.091 12.9 0.3 1.6 2 0 0 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain DUF4228 PF14009.6 CBY15947.1 - 0.4 11.1 7.0 1.1 9.7 6.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) Ras PF00071.22 CBY15948.1 - 1.5e-06 27.9 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY15948.1 - 3.2e-05 24.1 0.2 5.1e-05 23.5 0.2 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase UCH_N PF16674.5 CBY15948.1 - 0.01 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 Pkinase PF00069.25 CBY15949.1 - 8.6e-10 38.4 0.0 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15949.1 - 7e-07 28.8 0.0 8.4e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L4 PF00573.22 CBY15952.1 - 7e-24 84.6 2.4 9e-24 84.2 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family SSXT PF05030.12 CBY15953.1 - 1.1e-23 82.6 0.1 2.1e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) zf-LITAF-like PF10601.9 CBY15954.1 - 8.9e-19 67.5 13.4 1.3e-18 67.0 13.4 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain TMEM52 PF14979.6 CBY15954.1 - 0.55 10.1 11.9 8.6 6.3 0.1 2.2 2 0 0 2 2 2 0 Transmembrane 52 Med9 PF07544.13 CBY15955.1 - 2.3e-07 30.8 2.1 3.4e-07 30.2 2.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 HTH_25 PF13413.6 CBY15955.1 - 0.0069 16.2 1.4 0.013 15.3 1.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain 3HCDH_N PF02737.18 CBY15955.1 - 0.014 15.2 0.1 0.018 14.9 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IL32 PF15225.6 CBY15955.1 - 0.12 12.7 1.3 0.17 12.3 0.6 1.5 1 1 1 2 2 2 0 Interleukin 32 DUF1929 PF09118.11 CBY15956.1 - 0.081 13.2 0.1 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) DUF1192 PF06698.11 CBY15957.1 - 0.00011 22.2 2.3 0.00011 22.2 2.3 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1192) Vps51 PF08700.11 CBY15957.1 - 0.028 14.5 2.4 0.028 14.5 2.4 3.5 2 2 1 3 3 3 0 Vps51/Vps67 Emaravirus_P4 PF16505.5 CBY15957.1 - 0.47 9.4 10.4 0.089 11.8 3.1 2.1 2 0 0 2 2 2 0 P4 movement protein of Emaravirus, and the 30K superfamily HAP1_N PF04849.13 CBY15957.1 - 0.58 9.3 31.0 0.09 12.0 10.9 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Arg_decarbox_C PF17944.1 CBY15957.1 - 1.2 9.7 4.3 3.4 8.3 0.5 3.3 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Peptidase_M3_N PF08439.10 CBY15957.1 - 2.9 8.2 11.6 0.43 10.9 2.2 3.3 3 0 0 3 3 3 0 Oligopeptidase F DUF883 PF05957.13 CBY15957.1 - 7.3 7.3 22.2 0.43 11.2 6.1 3.4 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Lipase PF00151.19 CBY15958.1 - 1.4e-40 139.7 0.4 2.1e-40 139.0 0.4 1.2 1 1 0 1 1 1 1 Lipase Abhydrolase_1 PF00561.20 CBY15958.1 - 0.00041 20.1 0.0 0.00084 19.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY15958.1 - 0.00049 20.8 0.1 0.00057 20.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CBY15958.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 CBY15958.1 - 0.035 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.21 CBY15958.1 - 0.072 12.5 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 CBY15958.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 CBY15958.1 - 0.18 11.0 0.1 0.26 10.5 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 T4_deiodinase PF00837.17 CBY15960.1 - 1.6e-29 102.8 0.0 1.8e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Pkinase PF00069.25 CBY15961.1 - 1.6e-09 37.5 0.1 1.6e-09 37.5 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15961.1 - 2.1e-07 30.5 0.0 4.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 CBY15962.1 - 2.9e-37 126.0 13.7 3.1e-08 34.1 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY15962.1 - 1.9e-20 72.9 0.0 0.00089 19.5 0.0 5.5 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CBY15962.1 - 1.5e-10 40.6 0.7 2.7e-10 39.8 0.7 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 CBY15962.1 - 2e-06 27.8 0.1 0.00029 20.8 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY15962.1 - 0.015 14.6 0.0 0.11 11.8 0.0 2.3 3 0 0 3 3 3 0 WD40-like domain Nup160 PF11715.8 CBY15962.1 - 0.039 12.6 0.3 0.83 8.2 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ribosomal_L27e PF01777.18 CBY15963.1 - 5.2e-38 129.3 5.6 1.9e-37 127.5 6.4 1.4 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 CBY15963.1 - 4.5e-05 23.2 0.1 0.00011 22.0 0.1 1.6 1 0 0 1 1 1 1 KOW motif FGGY_C PF02782.16 CBY15964.1 - 9.7e-34 116.8 0.0 2e-33 115.8 0.0 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CBY15964.1 - 2.2e-32 112.6 0.0 1.1e-30 107.0 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_transf_34 PF05637.12 CBY15964.1 - 0.054 13.2 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family BcrAD_BadFG PF01869.20 CBY15964.1 - 0.11 12.0 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 CBY15964.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Cell division protein FtsA SRCR PF00530.18 CBY15965.1 - 6.5e-18 65.1 1.5 6.5e-18 65.1 1.5 2.1 3 0 0 3 3 3 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 CBY15965.1 - 0.00021 21.8 0.1 0.00092 19.7 0.0 2.2 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 CBY15965.1 - 0.0057 17.2 0.2 0.011 16.3 0.2 1.6 1 1 0 1 1 1 1 Hepsin, SRCR domain SNF2_N PF00176.23 CBY15966.1 - 1.3e-19 70.2 0.0 3.3e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY15966.1 - 1.8e-14 54.0 0.0 6.1e-14 52.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBY15966.1 - 1.4e-07 31.0 1.4 2e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Mito_carr PF00153.27 CBY15968.1 - 5.1e-60 199.4 2.8 1e-19 70.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 CBY15968.1 - 0.14 12.2 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) zf-RING_UBOX PF13445.6 CBY15969.1 - 2.4e-06 27.5 3.2 2.8e-06 27.2 3.2 1.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY15969.1 - 8.6e-06 25.5 1.2 9.8e-06 25.3 1.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY15969.1 - 2.4e-05 24.1 0.7 2.9e-05 23.8 0.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY15969.1 - 0.00061 19.5 1.1 0.00088 19.0 1.1 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBY15969.1 - 0.00098 19.2 2.0 0.0012 19.0 2.0 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBY15969.1 - 0.0012 19.1 0.9 0.0014 18.9 0.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY15969.1 - 0.0029 17.4 0.6 0.0033 17.3 0.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CBY15969.1 - 0.0039 17.0 0.2 0.0043 16.9 0.2 1.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CBY15969.1 - 0.0069 16.3 0.2 0.0083 16.1 0.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 CBY15969.1 - 0.0094 15.8 0.4 0.01 15.7 0.4 1.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-H2C2_2 PF13465.6 CBY15969.1 - 0.097 13.1 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger double domain Pkinase_Tyr PF07714.17 CBY15970.1 - 0.0057 16.0 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY15970.1 - 0.0057 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CBY15971.1 - 8.4e-13 48.3 0.0 1.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY15971.1 - 1.9e-08 33.9 0.0 0.00079 18.8 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_99 PF16317.5 CBY15972.1 - 2.1e-82 277.0 8.1 5.8e-82 275.6 8.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 CBY15972.1 - 2.5e-06 27.2 1.0 3.9e-05 23.3 0.3 2.2 1 1 0 2 2 2 1 Glycosyltransferase WbsX Glyco_hydro_71 PF03659.14 CBY15972.1 - 3.6e-06 26.0 2.0 7e-06 25.1 2.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 CBF PF03914.17 CBY15973.1 - 4.3e-30 105.0 0.6 1.1e-29 103.7 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.20 CBY15973.1 - 0.022 13.3 0.4 0.19 10.2 0.1 2.0 1 1 0 2 2 2 0 Adaptin N terminal region Kelch_2 PF07646.15 CBY15974.1 - 0.0002 21.2 0.9 0.2 11.7 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY15974.1 - 0.0021 18.0 2.0 0.29 11.2 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY15974.1 - 0.012 15.9 4.6 0.18 12.1 0.1 3.3 3 1 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY15974.1 - 0.087 12.9 0.2 3.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain CCDC85 PF10226.9 CBY15974.1 - 0.15 11.7 0.1 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 CCDC85 family Isochorismatase PF00857.20 CBY15975.1 - 1.7e-11 44.7 0.0 2.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family HSNSD PF12062.8 CBY15977.1 - 2.1e-77 260.9 3.5 3.4e-77 260.3 3.5 1.3 1 1 0 1 1 1 1 heparan sulfate-N-deacetylase DnaJ PF00226.31 CBY15978.1 - 5.5e-19 68.1 0.6 9.6e-19 67.3 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CBY15978.1 - 0.0086 16.1 2.2 0.013 15.5 2.2 1.3 1 0 0 1 1 1 1 Pam16 zf-TAZ PF02135.16 CBY15979.1 - 4.9e-09 36.5 13.4 7.6e-09 35.9 13.4 1.2 1 0 0 1 1 1 1 TAZ zinc finger DM PF00751.18 CBY15979.1 - 1.2 9.1 10.4 8.9 6.3 0.2 2.4 2 0 0 2 2 2 0 DM DNA binding domain Kelch_6 PF13964.6 CBY15980.1 - 0.0006 20.0 2.2 0.33 11.3 0.0 3.6 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CBY15980.1 - 0.05 13.2 1.6 0.86 9.2 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 CBY15980.1 - 0.2 11.7 1.1 25 5.1 0.0 2.8 3 0 0 3 3 3 0 Kelch motif rRNA_processing PF08524.11 CBY15981.1 - 2.3e-08 34.2 22.4 2.9e-08 33.9 22.4 1.1 1 0 0 1 1 1 1 rRNA processing FAM176 PF14851.6 CBY15981.1 - 0.14 11.8 6.5 0.17 11.6 6.5 1.1 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.12 CBY15981.1 - 8.2 6.2 12.8 8.5 6.1 12.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 CBY15981.1 - 9.5 4.6 15.7 10 4.5 15.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Matrilin_ccoil PF10393.9 CBY15983.1 - 0.02 14.8 1.6 0.064 13.1 1.6 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin cNMPbd_u2 PF16643.5 CBY15983.1 - 0.045 14.2 0.0 0.045 14.2 0.0 3.5 3 1 1 4 4 4 0 Unstructured region on cNMP-binding protein SlyX PF04102.12 CBY15983.1 - 0.36 11.5 5.5 0.1 13.3 0.7 2.6 2 0 0 2 2 2 0 SlyX NuDC PF16273.5 CBY15983.1 - 0.73 10.4 4.1 10 6.8 3.6 2.7 2 0 0 2 2 2 0 Nuclear distribution C domain DUF4485 PF14846.6 CBY15984.1 - 0.1 12.7 0.3 0.12 12.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) OAD_gamma PF04277.13 CBY15984.1 - 0.63 10.7 2.1 3.6 8.2 2.1 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ParcG PF10274.9 CBY15987.1 - 9.6e-54 182.3 0.0 1e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 CBY15987.1 - 0.09 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 VWA_2 PF13519.6 CBY15988.1 - 7.4e-05 23.3 1.7 0.00015 22.4 0.3 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY15988.1 - 0.067 12.6 0.3 0.16 11.3 0.3 1.6 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein PMP22_Claudin PF00822.20 CBY15989.1 - 4.1e-06 26.8 8.3 6.8e-06 26.0 8.3 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY15989.1 - 0.00087 19.5 6.2 0.0028 17.9 5.3 2.1 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 CBY15989.1 - 0.017 14.6 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 0 Clc-like TMEM37 PF15108.6 CBY15989.1 - 0.046 13.6 0.2 0.046 13.6 0.2 1.5 2 0 0 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family DnaJ PF00226.31 CBY15992.1 - 6.2e-07 29.5 1.9 0.0045 17.1 0.0 2.9 2 1 1 3 3 3 2 DnaJ domain RPT PF13446.6 CBY15992.1 - 0.04 13.8 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein HAUS6_N PF14661.6 CBY15992.1 - 0.18 11.3 5.5 0.39 10.3 5.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1943 PF09172.11 CBY15992.1 - 0.19 11.0 1.4 0.25 10.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF724 PF05266.14 CBY15992.1 - 4.9 6.9 13.3 0.34 10.7 8.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3010 PF11215.8 CBY15993.1 - 0.023 15.0 0.8 0.047 14.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3010) Not1 PF04054.15 CBY15994.1 - 0.037 13.0 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 ABC_membrane PF00664.23 CBY15995.1 - 1.3e-67 228.3 12.8 1.9e-67 227.8 12.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBY15995.1 - 1.4e-17 64.4 0.0 5.4e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CBY15995.1 - 6.4e-05 22.5 0.0 6.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CBY15995.1 - 0.024 13.4 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 CBY15995.1 - 0.024 14.8 1.9 0.22 11.7 0.5 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Chlam_PMP PF02415.17 CBY15996.1 - 0.027 14.9 0.0 0.32 11.6 0.0 2.9 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SH2_2 PF14633.6 CBY15997.1 - 3.8e-70 235.7 1.6 8.9e-70 234.4 1.6 1.6 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 CBY15997.1 - 4.1e-13 49.4 0.0 8.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CBY15997.1 - 7.9e-09 35.8 1.8 7.5e-08 32.7 0.0 3.1 4 0 0 4 4 4 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 CBY15997.1 - 0.00048 20.6 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_9 PF17674.1 CBY15997.1 - 0.00055 20.8 0.0 0.0053 17.6 0.0 2.7 2 1 0 2 2 2 1 HHH domain Tex_N PF09371.10 CBY15997.1 - 0.00092 18.9 0.4 0.0027 17.4 0.0 2.0 2 0 0 2 2 2 1 Tex-like protein N-terminal domain HTH_44 PF14641.6 CBY15997.1 - 0.0052 17.2 0.9 0.015 15.7 0.9 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_3 PF12836.7 CBY15997.1 - 0.024 14.9 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif FbpA PF05833.11 CBY15998.1 - 5.5e-40 137.5 12.7 8.2e-40 136.9 12.7 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CBY15998.1 - 3e-32 111.5 0.1 6.7e-32 110.4 0.1 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF5590 PF17881.1 CBY15998.1 - 0.019 15.0 0.0 0.067 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) RNA_pol_Rpb6 PF01192.22 CBY15998.1 - 0.083 12.8 1.5 0.18 11.7 0.1 2.4 2 1 1 3 3 3 0 RNA polymerase Rpb6 UPF0016 PF01169.19 CBY15999.1 - 1.6e-40 137.3 24.5 2.7e-20 72.5 5.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Sdh5 PF03937.16 CBY15999.1 - 0.12 12.4 2.9 0.55 10.2 0.2 2.8 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase Fib_alpha PF08702.10 CBY16000.1 - 0.00047 20.3 0.2 0.00062 20.0 0.2 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Glyco_hydro_1 PF00232.18 CBY16001.1 - 2.1e-144 481.4 2.2 2.4e-144 481.2 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 IL1 PF00340.19 CBY16005.1 - 0.021 14.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Interleukin-1 / 18 zf-C2H2_4 PF13894.6 CBY16006.1 - 3.4e-06 27.4 20.9 0.013 16.3 1.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY16006.1 - 3.3e-05 24.1 18.7 0.00038 20.8 1.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY16006.1 - 0.0014 18.9 0.7 0.0014 18.9 0.7 3.9 3 1 0 3 3 3 1 Zinc-finger double domain zinc_ribbon_15 PF17032.5 CBY16006.1 - 0.024 15.4 5.8 0.067 14.0 1.1 2.6 2 0 0 2 2 2 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 CBY16006.1 - 0.12 13.1 10.4 2.9 8.6 0.9 3.4 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF4359 PF14271.6 CBY16006.1 - 0.71 10.7 3.4 0.33 11.7 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) Ribosomal_L44 PF00935.19 CBY16006.1 - 3 8.4 7.7 3.4 8.2 2.7 2.9 1 1 1 2 2 2 0 Ribosomal protein L44 zf-C2H2_2 PF12756.7 CBY16006.1 - 6.6 7.1 17.1 43 4.5 0.1 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 CBY16006.1 - 6.8 6.4 11.3 1.4 8.6 3.0 2.9 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF842 PF05811.13 CBY16007.1 - 3.4e-13 49.4 10.4 4.5e-13 49.0 10.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF725 PF05267.12 CBY16007.1 - 0.0073 16.3 1.9 0.01 15.8 0.8 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF725) DUF5112 PF17139.4 CBY16007.1 - 0.011 15.2 0.6 0.013 15.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) Spore_III_AB PF09548.10 CBY16007.1 - 0.017 15.2 1.2 0.021 14.9 1.2 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ERp29 PF07749.12 CBY16007.1 - 0.087 13.7 1.6 0.23 12.4 0.3 2.0 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain NPV_P10 PF05531.12 CBY16007.1 - 0.11 13.0 1.5 4.7 7.7 0.5 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4456 PF14644.6 CBY16007.1 - 0.12 12.1 4.5 3.3 7.3 2.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4456) Mod_r PF07200.13 CBY16007.1 - 0.13 12.3 2.0 0.17 12.0 2.0 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.14 CBY16007.1 - 4 7.8 9.2 27 5.1 9.2 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Snf7 PF03357.21 CBY16008.1 - 5.7e-46 156.3 18.7 7.8e-46 155.8 18.7 1.2 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.12 CBY16008.1 - 0.011 16.1 5.8 0.016 15.6 5.8 1.2 1 0 0 1 1 1 0 SYF2 splicing factor DUF1869 PF08956.10 CBY16008.1 - 0.036 14.0 0.9 0.088 12.7 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) DUF5401 PF17380.2 CBY16008.1 - 0.049 11.7 2.9 0.054 11.6 2.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) STATa_Ig PF18214.1 CBY16008.1 - 3.1 7.8 7.5 0.51 10.4 3.4 1.8 2 1 0 2 2 2 0 STATa Immunoglobulin-like domain Tristanin_u2 PF16638.5 CBY16008.1 - 8.2 7.3 10.9 56 4.6 10.9 2.1 1 1 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Snf7 PF03357.21 CBY16009.1 - 3.5e-28 98.3 13.3 4.1e-28 98.1 13.3 1.0 1 0 0 1 1 1 1 Snf7 DUF4595 PF15283.6 CBY16009.1 - 0.01 15.9 0.4 0.012 15.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold Phage_TAC_12 PF12363.8 CBY16009.1 - 0.02 15.3 2.2 0.034 14.6 2.2 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC MerR-DNA-bind PF09278.11 CBY16009.1 - 0.4 11.2 3.9 36 5.0 0.0 3.5 2 1 1 3 3 3 0 MerR, DNA binding FeoB_Cyto PF17910.1 CBY16009.1 - 0.44 11.1 9.8 4.4 7.9 9.8 2.0 1 1 0 1 1 1 0 FeoB cytosolic helical domain PspA_IM30 PF04012.12 CBY16009.1 - 1.5 8.4 9.0 0.25 10.9 4.6 1.9 1 1 1 2 2 2 0 PspA/IM30 family Na_sulph_symp PF00939.19 CBY16010.1 - 4.8e-48 164.4 2.9 4e-34 118.5 0.0 2.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY16010.1 - 7.6e-15 54.9 10.4 3.3e-11 42.9 0.4 2.6 1 1 1 2 2 2 2 Citrate transporter Ribosomal_S17_N PF16205.5 CBY16011.1 - 5.1e-30 103.7 1.6 6.1e-30 103.4 1.6 1.1 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal FAD_binding_3 PF01494.19 CBY16013.1 - 5.4e-13 48.9 0.0 5.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 CBY16013.1 - 0.08 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase SIT PF15330.6 CBY16014.1 - 0.097 13.1 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT PAG PF15347.6 CBY16014.1 - 0.19 10.7 0.1 0.29 10.1 0.1 1.3 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched UPF0239 PF06783.11 CBY16015.1 - 0.068 13.4 0.5 0.068 13.4 0.5 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0239) CitG PF01874.16 CBY16015.1 - 0.12 12.0 5.5 0.28 10.8 5.5 1.6 1 1 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase TSP_1 PF00090.19 CBY16016.1 - 1.1e-08 35.1 23.6 1.1e-05 25.6 10.9 2.4 2 0 0 2 2 2 2 Thrombospondin type 1 domain 7tm_2 PF00002.24 CBY16017.1 - 6.4e-14 51.8 6.1 1.1e-13 51.0 6.1 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 CBY16017.1 - 0.011 16.0 0.3 0.021 15.1 0.3 1.5 1 0 0 1 1 1 0 Hormone receptor domain DUF1878 PF08963.10 CBY16017.1 - 0.11 13.1 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) Macoilin PF09726.9 CBY16020.1 - 7.7 4.9 18.7 9.1 4.7 18.7 1.0 1 0 0 1 1 1 0 Macoilin family Carn_acyltransf PF00755.20 CBY16021.1 - 1.1e-88 298.4 0.0 1.4e-88 298.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.20 CBY16022.1 - 4.7e-51 174.1 1.0 5.5e-51 173.9 1.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Kinesin PF00225.23 CBY16023.1 - 8.8e-99 330.6 0.1 8.8e-99 330.6 0.1 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY16023.1 - 2e-24 86.2 0.0 2e-24 86.2 0.0 3.1 4 0 0 4 4 4 1 Microtubule binding UPF0176_N PF17773.1 CBY16023.1 - 0.043 14.2 1.0 1.7 9.1 0.0 4.1 3 0 0 3 3 3 0 UPF0176 acylphosphatase like domain PTR PF12789.7 CBY16023.1 - 8.8 6.5 11.6 3.9 7.6 0.0 4.4 5 0 0 5 5 5 0 Phage tail repeat like UTP15_C PF09384.10 CBY16024.1 - 6.3e-29 100.5 1.2 1.1e-28 99.8 1.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CBY16024.1 - 8.3e-18 64.4 7.0 8.9e-05 23.2 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY16024.1 - 7e-09 35.9 0.3 0.11 12.9 0.0 5.8 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY16024.1 - 0.033 13.2 0.3 0.9 8.4 0.1 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CBY16024.1 - 0.078 11.5 0.1 6.4 5.2 0.0 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 CBY16024.1 - 0.82 10.2 3.4 52 4.5 0.0 3.9 4 1 0 4 4 4 0 PQQ-like domain DUF1977 PF09320.11 CBY16025.1 - 0.023 15.0 0.3 0.03 14.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) FXa_inhibition PF14670.6 CBY16026.1 - 0.0084 16.4 2.1 0.0084 16.4 2.1 17.1 12 4 3 16 16 16 2 Coagulation Factor Xa inhibitory site Ion_trans PF00520.31 CBY16027.1 - 1.8e-31 109.2 1.4 2.4e-31 108.9 1.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY16027.1 - 2.2e-14 53.1 3.3 3.6e-14 52.5 3.3 1.3 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.12 CBY16027.1 - 0.00014 20.7 1.1 0.00018 20.3 1.1 1.1 1 0 0 1 1 1 1 Polycystin cation channel EMC3_TMCO1 PF01956.16 CBY16027.1 - 0.21 11.3 1.0 1.7 8.3 0.5 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like BTB_2 PF02214.22 CBY16028.1 - 4.9e-24 84.5 0.0 9.1e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 CBY16028.1 - 3.4e-06 26.5 1.4 5e-06 25.9 1.4 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_3 PF16017.5 CBY16028.1 - 0.0036 17.4 0.1 0.0092 16.1 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Suf PF05843.14 CBY16032.1 - 2.7e-05 24.3 5.6 0.046 13.7 0.7 2.5 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CBY16032.1 - 6e-05 23.5 0.8 4.1 8.5 0.0 4.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY16032.1 - 0.0052 17.3 0.0 1.2 9.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY16032.1 - 0.0076 16.3 0.5 11 6.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4292 PF14125.6 CBY16032.1 - 0.018 14.7 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) PPR PF01535.20 CBY16032.1 - 0.073 13.3 0.7 24 5.5 0.1 3.5 3 0 0 3 3 3 0 PPR repeat U3_assoc_6 PF08640.11 CBY16032.1 - 0.14 12.2 4.5 2.9 8.0 0.4 2.8 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 CBY16032.1 - 0.21 10.7 10.9 0.044 12.9 1.4 3.5 1 1 2 3 3 3 0 NRDE-2, necessary for RNA interference Suf PF05843.14 CBY16033.1 - 1.1e-53 183.2 0.7 1.4e-53 182.8 0.7 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 CBY16033.1 - 0.0048 16.1 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference RIO1 PF01163.22 CBY16033.1 - 0.07 12.7 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 RIO1 family DUF4478 PF14793.6 CBY16033.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 1 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Ras_bdg_2 PF14847.6 CBY16033.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 DnaJ PF00226.31 CBY16034.1 - 2.3e-07 30.8 0.2 0.014 15.5 0.0 2.7 1 1 1 2 2 2 2 DnaJ domain F-box-like PF12937.7 CBY16034.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY16034.1 - 0.0018 18.1 1.0 0.025 14.5 0.0 2.6 3 0 0 3 3 3 1 F-box domain RPT PF13446.6 CBY16034.1 - 0.0022 17.9 0.6 0.012 15.5 0.1 2.4 3 0 0 3 3 3 1 A repeated domain in UCH-protein DUF3683 PF12447.8 CBY16034.1 - 0.054 13.6 0.9 0.17 12.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3683) DnaJ PF00226.31 CBY16035.1 - 4.5e-13 49.1 1.5 4.5e-13 49.1 1.5 3.8 3 1 1 4 4 4 1 DnaJ domain Ead_Ea22 PF13935.6 CBY16037.1 - 0.025 15.2 3.3 0.046 14.4 3.3 1.5 1 0 0 1 1 1 0 Ead/Ea22-like protein TPR_MLP1_2 PF07926.12 CBY16037.1 - 0.32 11.1 19.9 0.022 14.8 12.5 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 CBY16037.1 - 0.5 9.9 6.3 0.78 9.2 6.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4140 PF13600.6 CBY16037.1 - 0.92 10.0 3.6 2.3 8.7 3.6 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 CBY16037.1 - 0.99 9.4 7.2 0.24 11.5 3.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 CBY16037.1 - 2.8 8.0 25.5 0.027 14.6 16.9 2.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 CBY16037.1 - 5.5 7.6 11.6 0.68 10.5 6.9 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal LRS4 PF10422.9 CBY16037.1 - 8 6.0 15.7 17 4.9 15.7 1.5 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Lectin_C PF00059.21 CBY16038.1 - 1.5e-06 28.9 1.1 2.3e-06 28.3 1.1 1.2 1 0 0 1 1 1 1 Lectin C-type domain TrmO PF01980.16 CBY16039.1 - 4.3e-36 123.7 0.0 1.2e-35 122.3 0.0 1.8 1 1 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 CBY16039.1 - 0.0062 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 TrmO C-terminal domain Glyco_hydro_42C PF08533.10 CBY16039.1 - 0.014 15.1 0.1 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Lipase_GDSL_2 PF13472.6 CBY16040.1 - 5.9e-05 23.5 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BAF PF02961.14 CBY16041.1 - 4.2e-20 72.0 0.8 9.4e-20 70.9 0.2 1.8 2 0 0 2 2 2 1 Barrier to autointegration factor IMS_HHH PF11798.8 CBY16041.1 - 0.021 15.1 0.0 0.072 13.4 0.0 2.0 1 0 0 1 1 1 0 IMS family HHH motif VAPB_antitox PF02697.14 CBY16041.1 - 0.14 13.0 4.8 0.13 13.1 1.1 2.5 2 1 1 3 3 3 0 Putative antitoxin DUF4550 PF15084.6 CBY16042.1 - 8.4e-26 90.2 0.9 3.3e-25 88.3 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4550) Crinivirus_P26 PF07416.11 CBY16042.1 - 0.034 13.9 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Crinivirus P26 protein NusA_N PF08529.11 CBY16044.1 - 0.0066 16.8 1.0 0.0084 16.5 1.0 1.2 1 0 0 1 1 1 1 NusA N-terminal domain Homeodomain PF00046.29 CBY16046.1 - 5.6e-21 74.2 3.1 8.8e-21 73.5 3.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY16046.1 - 0.0031 17.4 0.2 0.0057 16.5 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 CBY16046.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Kri1 PF05178.12 CBY16047.1 - 0.031 14.8 4.6 0.05 14.2 4.6 1.3 1 0 0 1 1 1 0 KRI1-like family LPP20 PF02169.16 CBY16047.1 - 0.89 9.9 5.0 1.6 9.2 5.0 1.5 1 1 0 1 1 1 0 LPP20 lipoprotein Prefoldin PF02996.17 CBY16049.1 - 0.0046 16.9 2.0 0.009 15.9 0.8 1.8 2 0 0 2 2 2 1 Prefoldin subunit DUF4635 PF15466.6 CBY16049.1 - 0.02 14.4 0.2 0.025 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Fzo_mitofusin PF04799.13 CBY16049.1 - 0.13 11.8 1.1 0.17 11.5 0.8 1.4 1 1 1 2 2 2 0 fzo-like conserved region XhlA PF10779.9 CBY16049.1 - 0.44 10.8 2.9 1.1 9.5 1.4 1.9 2 0 0 2 2 2 0 Haemolysin XhlA Forkhead PF00250.18 CBY16051.1 - 1.3e-39 134.4 0.1 1.3e-39 134.4 0.1 2.0 2 0 0 2 2 2 1 Forkhead domain OmdA PF13376.6 CBY16051.1 - 0.019 15.0 0.8 0.046 13.7 0.8 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated GOLGA2L5 PF15070.6 CBY16051.1 - 0.045 12.4 1.5 0.064 11.9 1.5 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF4519 PF15012.6 CBY16051.1 - 0.48 10.6 7.6 0.74 10.0 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) p450 PF00067.22 CBY16052.1 - 1.9e-48 165.4 0.8 2.6e-48 164.9 0.8 1.1 1 0 0 1 1 1 1 Cytochrome P450 ELYS-bb PF16687.5 CBY16053.1 - 7.5e-15 54.5 0.1 1.2e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 beta-propeller of ELYS nucleoporin ANAPC4_WD40 PF12894.7 CBY16053.1 - 0.0091 16.3 0.0 3.3 8.1 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain UPF0565 PF10561.9 CBY16053.1 - 0.072 12.3 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 CUB PF00431.20 CBY16054.1 - 6.5e-11 42.6 0.1 2e-09 37.7 0.1 2.6 1 1 0 1 1 1 1 CUB domain FXa_inhibition PF14670.6 CBY16054.1 - 0.0013 19.0 11.3 0.0056 16.9 11.3 2.2 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site Homeodomain PF00046.29 CBY16056.1 - 2.8e-21 75.1 2.8 4.9e-21 74.3 2.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY16056.1 - 0.095 12.6 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF3584 PF12128.8 CBY16057.1 - 6.8e-06 23.9 20.4 8.3e-06 23.6 20.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Lectin_N PF03954.14 CBY16057.1 - 0.00029 20.6 9.3 0.00067 19.4 2.2 2.3 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Tup_N PF08581.10 CBY16057.1 - 0.00044 20.5 17.4 0.002 18.4 2.1 3.4 2 1 1 3 3 3 1 Tup N-terminal Apolipoprotein PF01442.18 CBY16057.1 - 0.0017 18.2 13.6 0.0026 17.6 3.2 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 CBY16057.1 - 0.0047 17.0 15.0 0.018 15.1 4.6 2.8 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus CASP_C PF08172.12 CBY16057.1 - 0.0047 16.3 1.2 0.0047 16.3 1.2 2.6 2 1 0 2 2 2 1 CASP C terminal CdvA PF18822.1 CBY16057.1 - 0.0057 16.5 2.6 0.0057 16.5 2.6 3.8 1 1 3 4 4 4 2 CdvA-like coiled-coil domain Golgin_A5 PF09787.9 CBY16057.1 - 0.006 16.1 11.4 0.006 16.1 11.4 2.0 1 1 1 2 2 2 1 Golgin subfamily A member 5 OmpH PF03938.14 CBY16057.1 - 0.0068 16.8 21.8 0.0099 16.2 4.9 2.1 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Filament PF00038.21 CBY16057.1 - 0.016 14.8 17.9 0.04 13.5 17.9 1.6 1 1 0 1 1 1 0 Intermediate filament protein Tweety PF04906.13 CBY16057.1 - 0.02 13.6 5.8 0.26 9.9 0.8 2.1 2 0 0 2 2 2 0 Tweety TPR_MLP1_2 PF07926.12 CBY16057.1 - 0.022 14.8 19.1 0.035 14.2 10.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ABC_tran_Xtn PF12848.7 CBY16057.1 - 0.023 14.7 3.1 0.023 14.7 3.1 2.5 2 2 0 2 2 2 0 ABC transporter Spc42p PF11544.8 CBY16057.1 - 0.029 14.4 10.8 0.21 11.6 3.0 3.0 2 2 0 2 2 2 0 Spindle pole body component Spc42p DUF641 PF04859.12 CBY16057.1 - 0.042 14.2 8.8 0.049 14.0 0.5 2.5 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Fez1 PF06818.15 CBY16057.1 - 0.05 14.1 15.0 0.088 13.3 14.9 1.5 1 1 0 1 1 1 0 Fez1 MbeB_N PF04837.12 CBY16057.1 - 0.055 13.8 1.6 0.055 13.8 1.6 3.5 2 1 1 3 3 3 0 MbeB-like, N-term conserved region KfrA_N PF11740.8 CBY16057.1 - 0.063 14.0 5.1 2.1 9.0 0.2 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term ArsR PF09824.9 CBY16057.1 - 0.074 12.7 3.1 0.093 12.3 0.4 2.3 1 1 0 2 2 2 0 ArsR transcriptional regulator Prominin PF05478.11 CBY16057.1 - 0.088 10.8 14.0 0.11 10.4 14.0 1.0 1 0 0 1 1 1 0 Prominin AIP3 PF03915.13 CBY16057.1 - 0.1 11.7 18.8 0.17 11.0 18.3 1.5 1 1 1 2 2 2 0 Actin interacting protein 3 GAS PF13851.6 CBY16057.1 - 0.1 11.9 20.7 0.36 10.2 20.7 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PmrD PF11183.8 CBY16057.1 - 0.13 12.4 3.0 1.3 9.1 0.5 2.4 1 1 1 2 2 2 0 Polymyxin resistance protein PmrD Cluap1 PF10234.9 CBY16057.1 - 0.13 11.7 18.6 0.027 13.9 6.5 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF948 PF06103.11 CBY16057.1 - 0.15 12.3 10.5 0.31 11.3 0.7 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 CBY16057.1 - 0.17 12.3 14.3 1.4 9.4 0.4 4.3 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 CBY16057.1 - 0.2 11.7 23.9 0.26 11.4 10.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HisKA_3 PF07730.13 CBY16057.1 - 0.22 12.0 2.9 5.4 7.6 0.2 3.0 3 1 0 3 3 3 0 Histidine kinase AAA_27 PF13514.6 CBY16057.1 - 0.24 10.9 5.2 0.25 10.9 0.4 2.1 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 CBY16057.1 - 0.3 10.1 18.5 1.4 8.0 18.4 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 CBY16057.1 - 0.31 11.2 20.3 1.4 9.1 6.7 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 CBY16057.1 - 0.31 11.0 18.2 1.1 9.2 6.6 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF2205 PF10224.9 CBY16057.1 - 0.33 11.0 16.3 0.39 10.7 4.2 3.4 1 1 3 4 4 4 0 Short coiled-coil protein DUF1515 PF07439.11 CBY16057.1 - 0.34 11.0 6.6 0.27 11.3 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Nup88 PF10168.9 CBY16057.1 - 0.37 8.5 14.4 0.49 8.2 14.4 1.0 1 0 0 1 1 1 0 Nuclear pore component Syntaxin-6_N PF09177.11 CBY16057.1 - 0.4 11.3 13.2 2e+03 -0.6 13.2 3.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF883 PF05957.13 CBY16057.1 - 0.52 10.9 11.1 1.7 9.3 1.9 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.15 CBY16057.1 - 0.53 9.8 13.5 2.1 7.8 13.6 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1525 PF07511.11 CBY16057.1 - 0.58 10.3 7.4 0.2 11.8 1.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1525) SHE3 PF17078.5 CBY16057.1 - 0.59 9.8 20.3 4.1 7.0 8.7 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 CBY16057.1 - 0.64 10.1 18.9 0.14 12.2 8.0 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding PRKG1_interact PF15898.5 CBY16057.1 - 0.82 10.6 15.4 1.3 10.0 3.1 3.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 CBY16057.1 - 0.88 8.9 16.8 3.6 6.8 16.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 CBY16057.1 - 0.91 9.8 22.0 1 9.6 3.0 4.0 3 1 1 4 4 4 0 Haemolysin XhlA TolA_bind_tri PF16331.5 CBY16057.1 - 1 9.5 16.5 1 9.5 6.7 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF5446 PF17522.2 CBY16057.1 - 1.1 9.5 8.7 3.8 7.7 0.3 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5446) TEX13 PF15186.6 CBY16057.1 - 1.1 9.0 10.4 2.9 7.5 0.5 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF1664 PF07889.12 CBY16057.1 - 1.1 9.3 17.4 2.7 8.0 5.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 CBY16057.1 - 1.1 9.7 14.4 7.1e+03 -2.5 13.9 3.6 1 1 0 1 1 0 0 Cell division protein ZapB ApoO PF09769.9 CBY16057.1 - 1.2 9.1 3.3 45 4.0 2.9 2.9 1 1 1 2 2 2 0 Apolipoprotein O Muted PF14942.6 CBY16057.1 - 1.3 9.3 20.2 1.5 9.1 10.0 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TSC22 PF01166.18 CBY16057.1 - 1.5 9.2 7.5 11 6.5 0.2 3.5 2 1 1 3 3 3 0 TSC-22/dip/bun family HsbA PF12296.8 CBY16057.1 - 1.5 9.3 9.3 0.75 10.2 1.4 3.2 1 1 1 3 3 2 0 Hydrophobic surface binding protein A Spc7 PF08317.11 CBY16057.1 - 1.5 7.6 23.1 1.8 7.4 7.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FAP206 PF12018.8 CBY16057.1 - 1.7 8.1 11.0 0.54 9.7 6.1 2.1 1 1 1 2 2 2 0 Domain of unknown function Spectrin PF00435.21 CBY16057.1 - 1.8 9.1 17.6 2.5 8.6 6.1 2.7 1 1 2 3 3 3 0 Spectrin repeat HAUS-augmin3 PF14932.6 CBY16057.1 - 1.8 8.1 16.0 1.2 8.6 9.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DivIC PF04977.15 CBY16057.1 - 2.1 8.2 15.7 4.4 7.2 7.2 3.2 2 1 1 3 3 3 0 Septum formation initiator HIP1_clath_bdg PF16515.5 CBY16057.1 - 2.2 8.9 18.3 4.5 8.0 1.5 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5082 PF16888.5 CBY16057.1 - 2.6 8.3 22.1 1.5 9.1 4.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) CHASE6_C PF17150.4 CBY16057.1 - 2.8 8.7 6.0 15 6.3 0.1 2.7 2 1 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain Csm1_N PF18504.1 CBY16057.1 - 2.9 8.3 17.7 0.12 12.8 2.5 3.7 1 1 2 3 3 3 0 Csm1 N-terminal domain FAM76 PF16046.5 CBY16057.1 - 3 7.1 18.2 2.6 7.3 2.6 2.1 1 1 1 2 2 2 0 FAM76 protein COG2 PF06148.11 CBY16057.1 - 3 7.9 12.8 1.2 9.2 3.1 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 BST2 PF16716.5 CBY16057.1 - 3 8.5 19.0 6.5 7.4 2.6 3.1 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 PI_PP_I PF18363.1 CBY16057.1 - 3.3 8.0 8.1 0.68 10.1 0.6 2.8 1 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain Fzo_mitofusin PF04799.13 CBY16057.1 - 3.3 7.2 15.7 11 5.5 7.2 2.9 1 1 0 2 2 2 0 fzo-like conserved region TMPIT PF07851.13 CBY16057.1 - 3.6 6.7 17.9 1.1 8.5 4.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein LPP PF04728.13 CBY16057.1 - 4.1 7.9 20.3 24 5.4 0.5 5.0 2 2 2 5 5 5 0 Lipoprotein leucine-zipper DUF4254 PF14063.6 CBY16057.1 - 4.6 7.1 13.7 0.78 9.6 4.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF4254) YabA PF06156.13 CBY16057.1 - 4.6 7.9 14.2 58 4.4 6.5 3.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF2203 PF09969.9 CBY16057.1 - 5 7.9 13.3 8.6e+03 -2.6 13.3 2.8 1 1 0 1 1 0 0 Uncharacterized conserved protein (DUF2203) DUF5595 PF18077.1 CBY16057.1 - 5 7.3 9.1 1.9 8.6 0.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) Mod_r PF07200.13 CBY16057.1 - 5.1 7.2 22.1 1.2 9.2 11.6 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Pinin_SDK_memA PF04696.13 CBY16057.1 - 5.3 7.1 14.7 3.3 7.8 7.3 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region NRBF2 PF08961.10 CBY16057.1 - 7 6.2 15.2 0.067 12.8 3.7 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator V_ATPase_I PF01496.19 CBY16057.1 - 7.8 4.3 14.6 0.53 8.1 6.7 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CorA PF01544.18 CBY16057.1 - 8.7 5.6 12.9 10 5.3 10.8 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Rx_N PF18052.1 CBY16057.1 - 9.5 6.6 14.1 1.7 9.0 0.8 3.0 2 2 0 2 2 2 0 Rx N-terminal domain DUF948 PF06103.11 CBY16058.1 - 0.067 13.4 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Pkinase_Tyr PF07714.17 CBY16060.1 - 1.3e-28 100.0 0.0 1.2e-27 96.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY16060.1 - 4.1e-20 72.3 0.0 1.1e-19 70.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Guanylate_cyc PF00211.20 CBY16062.1 - 4.4e-49 166.6 0.0 7e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 CBY16063.1 - 1.6e-31 109.7 0.0 1.8e-31 109.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY16063.1 - 6.2e-18 65.0 0.0 9.2e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.9 CBY16063.1 - 0.022 15.3 5.1 0.044 14.4 5.1 1.7 1 1 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Cdh1_DBD_1 PF18196.1 CBY16063.1 - 1.2 9.5 6.9 0.77 10.1 4.9 1.6 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 PI-PLC-X PF00388.19 CBY16066.1 - 1.3e-57 193.5 0.0 1e-56 190.6 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY16066.1 - 2.7e-39 134.0 1.6 3.2e-39 133.8 0.3 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF1720 PF08226.11 CBY16068.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) Astacin PF01400.24 CBY16069.1 - 1.5e-11 44.2 0.0 1.5e-11 44.2 0.0 2.8 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY16069.1 - 0.0061 16.7 5.7 0.0061 16.7 5.7 3.3 3 0 0 3 3 3 2 Calcium-binding EGF domain Ldl_recept_a PF00057.18 CBY16069.1 - 0.046 13.9 0.7 0.046 13.9 0.7 4.0 4 0 0 4 4 4 0 Low-density lipoprotein receptor domain class A MID_MedPIWI PF18296.1 CBY16069.1 - 0.11 12.3 3.5 0.19 11.5 3.5 1.3 1 0 0 1 1 1 0 MID domain of medPIWI SOG2 PF10428.9 CBY16069.1 - 0.38 9.9 12.2 0.6 9.2 12.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF908 PF06012.12 CBY16069.1 - 1.2 8.4 9.6 1.8 7.9 9.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) 7tm_2 PF00002.24 CBY16070.1 - 1.2e-07 31.2 4.7 1.6e-07 30.8 4.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1084 PF06454.11 CBY16070.1 - 0.026 13.9 1.3 0.039 13.3 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) Bax1-I PF01027.20 CBY16070.1 - 0.047 13.5 7.4 0.083 12.7 7.1 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DBR1 PF05011.13 CBY16071.1 - 0.029 14.8 0.5 0.036 14.5 0.5 1.2 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain DUF2605 PF10792.9 CBY16071.1 - 0.081 12.9 0.9 0.13 12.2 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) Thioredoxin_8 PF13905.6 CBY16071.1 - 0.18 12.1 1.0 0.23 11.8 1.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like DUF749 PF05370.11 CBY16072.1 - 0.0091 16.1 0.4 0.011 15.8 0.4 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF749) LCM PF04072.14 CBY16074.1 - 6.4e-11 42.5 0.1 1.1e-10 41.8 0.1 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Phospholip_A2_1 PF00068.19 CBY16075.1 - 1.4e-20 73.8 6.8 2.1e-20 73.2 6.8 1.2 1 0 0 1 1 1 1 Phospholipase A2 SNARE PF05739.19 CBY16078.1 - 7.9e-14 51.4 0.2 1.4e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 SNARE domain DUF16 PF01519.16 CBY16078.1 - 0.00038 20.9 1.6 0.00045 20.7 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF16 Syntaxin PF00804.25 CBY16078.1 - 0.00039 20.2 0.8 0.00065 19.4 0.8 1.4 1 0 0 1 1 1 1 Syntaxin Use1 PF09753.9 CBY16078.1 - 0.074 12.8 5.8 0.1 12.3 5.8 1.2 1 1 0 1 1 1 0 Membrane fusion protein Use1 UPF0242 PF06785.11 CBY16078.1 - 0.27 11.3 4.4 0.39 10.8 4.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-5_N PF11416.8 CBY16079.1 - 0.00012 21.2 0.0 0.00034 19.7 0.0 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Cytochrom_B562 PF07361.11 CBY16079.1 - 0.019 15.6 2.4 0.04 14.6 2.4 1.5 1 0 0 1 1 1 0 Cytochrome b562 ECH_1 PF00378.20 CBY16081.1 - 1.9e-42 145.3 0.4 3.4e-42 144.5 0.4 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY16081.1 - 9.4e-23 81.2 0.1 3.7e-21 76.0 0.0 1.8 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBY16082.1 - 3.7e-08 33.0 0.2 4.9e-07 29.3 0.0 2.2 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase BPS PF08947.10 CBY16082.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 BPS (Between PH and SH2) IFT20 PF14931.6 CBY16084.1 - 0.0084 16.3 0.6 0.016 15.4 0.6 1.4 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 IBN_N PF03810.19 CBY16084.1 - 0.056 13.4 3.2 1 9.3 0.1 3.1 3 0 0 3 3 3 0 Importin-beta N-terminal domain zf-TAZ PF02135.16 CBY16085.1 - 1.6e-09 38.0 14.1 2.5e-09 37.5 14.1 1.2 1 0 0 1 1 1 1 TAZ zinc finger DM PF00751.18 CBY16085.1 - 0.55 10.2 11.6 5.9 6.9 6.1 2.4 2 0 0 2 2 2 0 DM DNA binding domain Pkinase PF00069.25 CBY16086.1 - 1.5e-48 165.5 0.0 2.9e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY16086.1 - 1.2e-28 100.2 0.0 2.2e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY16086.1 - 1.4e-05 24.6 0.1 5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Gag_p24 PF00607.20 CBY16086.1 - 0.0099 15.8 0.5 2.5 7.9 0.1 2.6 1 1 1 2 2 2 2 gag gene protein p24 (core nucleocapsid protein) Kdo PF06293.14 CBY16086.1 - 0.018 14.4 0.1 0.048 13.0 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4805 PF16063.5 CBY16087.1 - 0.057 12.8 0.1 0.057 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) zf-C2H2_4 PF13894.6 CBY16089.1 - 5.7e-05 23.6 20.8 0.013 16.3 0.1 5.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY16089.1 - 0.0058 17.0 0.1 0.0058 17.0 0.1 5.4 5 1 0 5 5 5 1 Zinc-finger double domain DUF1610 PF07754.11 CBY16089.1 - 0.088 12.8 1.0 0.088 12.8 1.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf_UBZ PF18439.1 CBY16089.1 - 0.21 11.2 0.1 0.21 11.2 0.1 3.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 CBY16089.1 - 0.46 10.7 5.2 13 6.0 0.2 2.9 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 CBY16089.1 - 2.1 9.0 28.4 4.5 7.9 1.7 5.8 5 1 0 5 5 5 0 Zinc finger, C2H2 type Kazal_2 PF07648.15 CBY16090.1 - 5.1e-05 23.3 0.2 6.7e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CBY16090.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.4 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain AdoHcyase_NAD PF00670.21 CBY16091.1 - 5.1e-38 130.7 0.3 6.5e-38 130.4 0.3 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 CBY16091.1 - 2.6e-16 59.6 0.0 2.9e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase Rota_NS35 PF02509.14 CBY16091.1 - 0.081 11.9 0.1 0.097 11.7 0.1 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 WD40 PF00400.32 CBY16092.1 - 1.4e-07 32.1 0.6 0.0015 19.3 0.1 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY16092.1 - 0.00011 22.4 0.0 0.0041 17.4 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 CBY16092.1 - 0.045 12.4 0.0 5.9 5.4 0.0 2.5 2 1 1 3 3 3 0 beta-propeller of ELYS nucleoporin WD40_like PF17005.5 CBY16092.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.6 1 1 0 1 1 1 0 WD40-like domain DUF4492 PF14899.6 CBY16093.1 - 0.015 15.2 6.7 2.2 8.3 3.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Hanta_G2 PF01561.16 CBY16093.1 - 0.019 13.7 2.7 0.03 13.0 2.7 1.3 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 DUF2427 PF10348.9 CBY16093.1 - 0.03 14.1 1.9 0.03 14.1 1.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) DUF2615 PF11027.8 CBY16093.1 - 0.51 10.5 0.1 0.51 10.5 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) DUF2070 PF09843.9 CBY16093.1 - 4.8 5.4 24.1 5.6 5.1 11.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Hormone_recep PF00104.30 CBY16094.1 - 2.3e-13 50.2 0.1 1.7e-12 47.4 0.1 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Peptidase_M50 PF02163.22 CBY16095.1 - 9e-13 48.1 0.1 2e-12 46.9 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M50 Peptidase_M50B PF13398.6 CBY16095.1 - 0.0017 18.1 1.9 0.0017 18.1 1.9 1.9 2 0 0 2 2 2 1 Peptidase M50B-like PDZ PF00595.24 CBY16095.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain GGN PF15685.5 CBY16096.1 - 0.3 10.1 0.0 0.33 10.0 0.0 1.0 1 0 0 1 1 1 0 Gametogenetin Ion_trans PF00520.31 CBY16098.1 - 2.3e-07 30.3 0.1 3.8e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CBY16098.1 - 0.081 11.6 2.3 0.12 11.0 2.3 1.2 1 0 0 1 1 1 0 Polycystin cation channel COX4 PF02936.14 CBY16098.1 - 0.091 12.8 0.0 4.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Voltage_CLC PF00654.20 CBY16098.1 - 0.11 11.8 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Herpes_US9 PF06072.11 CBY16098.1 - 1 9.3 3.8 0.96 9.4 2.5 1.6 1 1 0 1 1 1 0 Alphaherpesvirus tegument protein US9 TMPIT PF07851.13 CBY16099.1 - 2.9e-74 250.2 14.3 5.3e-74 249.4 14.3 1.4 1 0 0 1 1 1 1 TMPIT-like protein HAS-barrel PF09378.10 CBY16102.1 - 0.07 13.3 0.0 0.081 13.1 0.0 1.1 1 0 0 1 1 1 0 HAS barrel domain Tfb2_C PF18307.1 CBY16102.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain Pkinase PF00069.25 CBY16104.1 - 2.4e-10 40.3 2.3 3.2e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY16104.1 - 7.9e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HLH PF00010.26 CBY16106.1 - 5.8e-15 55.0 0.8 5.8e-15 55.0 0.8 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain LpxI_C PF06230.11 CBY16106.1 - 0.078 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 LpxI C-terminal domain Ribosomal_60s PF00428.19 CBY16106.1 - 0.34 11.5 8.6 1.1 9.9 2.3 2.6 1 1 1 2 2 2 0 60s Acidic ribosomal protein FAM153 PF15722.5 CBY16106.1 - 0.62 10.4 4.2 0.38 11.1 1.2 2.1 2 0 0 2 2 2 0 FAM153 family Cytochrom_C_asm PF01578.20 CBY16107.1 - 0.089 12.6 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein DUF3284 PF11687.8 CBY16107.1 - 0.45 10.4 3.1 0.47 10.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3284) GDP_Man_Dehyd PF16363.5 CBY16108.1 - 4.1e-36 125.0 0.0 5.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY16108.1 - 5.9e-33 114.3 0.0 7.1e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBY16108.1 - 3.5e-14 52.5 0.0 6.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CBY16108.1 - 5e-08 33.0 0.0 7.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CBY16108.1 - 2.5e-07 30.1 0.0 4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CBY16108.1 - 2e-05 23.9 0.0 3.3e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 CBY16108.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Sporozoite_P67 PF05642.11 CBY16109.1 - 0.00037 18.8 4.3 0.0005 18.3 4.3 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Homeodomain PF00046.29 CBY16109.1 - 0.00051 19.8 0.9 0.001 18.9 0.9 1.5 1 0 0 1 1 1 1 Homeodomain TLP-20 PF06088.11 CBY16109.1 - 0.023 14.6 0.2 0.037 13.9 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 CBY16109.1 - 0.037 13.7 0.2 0.059 13.0 0.2 1.3 1 0 0 1 1 1 0 FAM176 family Granulin PF00396.18 CBY16110.1 - 3.6 8.0 12.6 2.4 8.6 4.1 3.1 3 0 0 3 3 3 0 Granulin FKBP_C PF00254.28 CBY16111.1 - 4e-20 71.9 0.0 6e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 CBY16111.1 - 2.7e-09 37.4 0.5 5.6e-09 36.3 0.5 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY16111.1 - 5.2e-08 31.9 1.7 0.0017 17.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY16111.1 - 1.1e-07 31.0 1.9 0.0039 16.6 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY16111.1 - 1.3e-07 30.9 1.0 0.00057 19.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CBY16111.1 - 0.0032 17.3 0.8 0.37 10.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair RepB-RCR_reg PF10723.9 CBY16111.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Replication regulatory protein RepB Evr1_Alr PF04777.13 CBY16112.1 - 2.1e-18 66.7 0.2 4.6e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Erv1 / Alr family DnaJ PF00226.31 CBY16114.1 - 1.6e-24 85.8 2.8 2.4e-24 85.2 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain Prominin PF05478.11 CBY16114.1 - 0.036 12.1 8.7 0.045 11.7 8.7 1.1 1 0 0 1 1 1 0 Prominin CFTR_R PF14396.6 CBY16114.1 - 0.07 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Renin_r PF07850.14 CBY16115.1 - 0.0067 17.0 0.0 0.019 15.6 0.0 1.7 1 1 0 2 2 2 1 Renin receptor-like protein OppC_N PF12911.7 CBY16115.1 - 2.8 8.0 5.9 12 6.0 3.4 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DFRP_C PF16543.5 CBY16117.1 - 2.7 8.5 18.4 0.098 13.2 5.0 2.9 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 RasGAP PF00616.19 CBY16118.1 - 0.06 13.0 5.2 0.08 12.6 5.2 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Nop25 PF09805.9 CBY16118.1 - 0.094 13.2 11.1 0.15 12.6 11.1 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) FAM60A PF15396.6 CBY16118.1 - 0.44 10.5 6.6 0.46 10.5 6.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Aha1_N PF09229.11 CBY16119.1 - 9e-25 87.5 2.2 9e-25 87.5 2.2 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CBY16119.1 - 3.8e-19 69.2 1.1 1e-18 67.8 1.1 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Pkinase PF00069.25 CBY16120.1 - 1.7e-48 165.3 0.0 2e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY16120.1 - 1e-24 87.3 0.0 1.3e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY16120.1 - 1.3e-06 27.9 0.0 2.8e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBY16120.1 - 0.0059 16.2 0.0 0.022 14.4 0.0 1.8 1 1 1 2 2 2 1 RIO1 family FTA2 PF13095.6 CBY16120.1 - 0.024 14.2 0.3 4.7 6.8 0.4 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBY16120.1 - 0.028 13.2 0.0 0.037 12.8 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CBY16120.1 - 0.037 13.9 0.0 0.4 10.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CBY16120.1 - 0.052 12.9 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.6 CBY16121.1 - 1e-25 89.4 0.1 6e-08 32.8 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY16121.1 - 3.7e-23 81.9 0.0 4.8e-11 43.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DHHC PF01529.20 CBY16121.1 - 5.6e-23 81.5 7.9 5.6e-23 81.5 7.9 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_3 PF13606.6 CBY16121.1 - 2.4e-21 73.5 0.0 0.0035 17.7 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 CBY16121.1 - 5.3e-21 74.7 0.1 2.5e-07 31.1 0.1 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY16121.1 - 9.8e-21 73.2 0.4 7.7e-05 23.0 0.0 6.6 6 1 1 7 7 7 4 Ankyrin repeat GWT1 PF06423.12 CBY16121.1 - 4.5 7.4 8.3 11 6.2 7.8 2.1 1 1 0 1 1 1 0 GWT1 Peptidase_M1 PF01433.20 CBY16123.1 - 2.9e-48 164.3 0.0 4.1e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY16123.1 - 7.1e-29 101.3 0.0 1.1e-28 100.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Ank_2 PF12796.7 CBY16124.1 - 0.049 14.2 0.0 0.073 13.7 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY16124.1 - 0.07 13.7 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY16124.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY16125.1 - 0.1 13.2 0.0 0.19 12.3 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Kelch_6 PF13964.6 CBY16126.1 - 5.7e-06 26.4 0.0 0.29 11.5 0.0 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY16126.1 - 0.0054 16.7 0.4 2.3 8.3 0.2 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY16126.1 - 0.15 12.1 0.1 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 CBY16127.1 - 1e-35 120.8 13.4 1.2e-07 31.8 0.0 6.3 5 2 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CBY16127.1 - 2.6e-34 116.7 3.1 2.8e-07 30.4 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CBY16127.1 - 3.2e-33 113.5 14.7 1e-08 35.0 0.3 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY16127.1 - 3.5e-31 106.5 6.6 1.1e-06 28.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CBY16127.1 - 6.8e-26 89.2 10.9 0.00026 20.8 0.2 6.9 6 2 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CBY16127.1 - 7.4e-25 86.7 13.2 1.2e-06 28.6 0.0 6.7 7 1 0 7 7 7 5 Galactose oxidase, central domain SDF PF00375.18 CBY16128.1 - 2.6e-43 148.5 1.6 2.9e-43 148.4 1.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family zf-RING_2 PF13639.6 CBY16131.1 - 2e-09 37.6 7.6 2.6e-09 37.3 7.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY16131.1 - 3.9e-08 33.2 2.7 3.9e-08 33.2 2.7 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY16131.1 - 1.5e-07 31.1 7.2 2e-07 30.8 7.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY16131.1 - 3.1e-07 30.1 5.6 5.4e-07 29.4 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY16131.1 - 4.7e-07 29.6 6.4 3.1e-05 23.7 1.6 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY16131.1 - 5.4e-07 29.3 6.7 7.4e-07 28.9 6.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CBY16131.1 - 1.5e-06 28.0 6.5 2.5e-06 27.3 6.5 1.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBY16131.1 - 1.9e-06 27.9 5.3 6.9e-06 26.1 5.3 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 CBY16131.1 - 6.2e-05 22.5 0.2 7.2e-05 22.3 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Rad50_zn_hook PF04423.14 CBY16131.1 - 0.00093 19.0 0.7 0.3 11.0 0.1 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C3HC4_2 PF13923.6 CBY16131.1 - 0.0042 16.9 9.1 0.04 13.8 9.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 CBY16131.1 - 0.017 15.6 3.9 2.7 8.5 1.0 2.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 CBY16131.1 - 0.018 14.9 1.4 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C3HC4_5 PF17121.5 CBY16131.1 - 0.034 14.1 3.9 0.16 11.8 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 CBY16131.1 - 0.036 14.3 5.6 0.57 10.5 0.5 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FANCL_C PF11793.8 CBY16131.1 - 0.05 13.8 7.1 0.15 12.3 7.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_IE-1 PF05290.11 CBY16131.1 - 0.072 13.0 2.6 0.083 12.8 2.6 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DZR PF12773.7 CBY16131.1 - 0.17 12.0 3.8 0.8 9.8 3.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 CBY16131.1 - 0.18 11.9 3.3 0.39 10.8 3.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-H2C2_2 PF13465.6 CBY16131.1 - 0.19 12.2 0.9 0.19 12.2 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger double domain YacG PF03884.14 CBY16131.1 - 0.21 11.3 3.3 4.1 7.2 0.1 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Prok-RING_1 PF14446.6 CBY16131.1 - 0.23 11.4 5.7 2.3 8.2 0.0 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.21 CBY16131.1 - 0.26 11.5 8.3 3.8 7.7 8.0 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_11 PF17123.5 CBY16131.1 - 0.31 10.8 5.3 0.15 11.8 2.5 2.0 2 1 0 2 2 2 0 RING-like zinc finger UBZ_FAAP20 PF15750.5 CBY16131.1 - 0.44 10.5 7.9 0.61 10.1 0.3 2.5 3 0 0 3 3 2 0 Ubiquitin-binding zinc-finger DUF2225 PF09986.9 CBY16131.1 - 0.96 9.1 4.1 12 5.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-rbx1 PF12678.7 CBY16131.1 - 1 9.7 8.0 5.1 7.5 8.0 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C2H2_4 PF13894.6 CBY16131.1 - 2.4 9.2 9.1 3 8.9 0.3 2.8 3 0 0 3 3 2 0 C2H2-type zinc finger zf-MIZ PF02891.20 CBY16131.1 - 4.5 7.1 8.8 37 4.2 8.8 2.2 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zinc_ribbon_9 PF14369.6 CBY16131.1 - 5.4 7.4 10.0 3.5 8.0 2.2 3.1 2 1 1 3 3 3 0 zinc-ribbon RhoGEF PF00621.20 CBY16133.1 - 1.2e-32 113.6 0.2 2.5e-32 112.6 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain Inhibitor_I36 PF03995.13 CBY16133.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor family I36 Pkinase PF00069.25 CBY16134.1 - 1e-35 123.4 0.1 1.6e-35 122.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY16134.1 - 1e-29 103.7 0.0 1.5e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.21 CBY16134.1 - 9.3e-06 25.9 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain DUF4597 PF15366.6 CBY16134.1 - 0.0078 15.9 0.3 0.023 14.4 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4597) zf-C4 PF00105.18 CBY16135.1 - 7e-12 45.6 3.4 1.5e-11 44.6 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY16135.1 - 4.4e-10 39.5 2.7 1e-09 38.3 2.7 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor AgrB PF04647.15 CBY16135.1 - 0.071 12.4 0.4 0.12 11.6 0.4 1.3 1 0 0 1 1 1 0 Accessory gene regulator B SET PF00856.28 CBY16137.1 - 8.2e-20 71.9 0.1 1.2e-18 68.1 0.1 2.0 1 1 0 1 1 1 1 SET domain Y2_Tnp PF04986.13 CBY16137.1 - 0.045 13.8 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Putative transposase LisH PF08513.11 CBY16138.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 LisH KH_1 PF00013.29 CBY16140.1 - 0.0038 17.0 1.3 0.0069 16.2 1.3 1.4 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 CBY16140.1 - 0.11 12.6 0.1 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Krr1 KH1 domain TctA PF01970.16 CBY16140.1 - 0.25 10.0 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Dus PF01207.17 CBY16141.1 - 4.5e-55 186.9 0.2 8.6e-55 186.0 0.2 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CBY16141.1 - 0.0073 15.8 0.1 0.015 14.8 0.1 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein PA28_alpha PF02251.18 CBY16141.1 - 0.013 15.5 0.1 0.053 13.6 0.0 1.9 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit DHDPS PF00701.22 CBY16141.1 - 0.063 12.0 0.3 4.9 5.8 0.0 2.8 3 0 0 3 3 3 0 Dihydrodipicolinate synthetase family UCH PF00443.29 CBY16142.1 - 1.9e-09 37.4 0.1 1.9e-09 37.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 CBY16142.1 - 4.3e-08 32.5 10.1 0.00011 21.8 1.7 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif UCH_1 PF13423.6 CBY16142.1 - 0.00036 20.2 1.2 0.0048 16.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RAP80_UIM PF18282.1 CBY16142.1 - 1.7 8.5 9.1 0.4 10.5 5.0 2.0 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif CDI PF02234.19 CBY16144.1 - 0.064 13.5 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Band_7 PF01145.25 CBY16145.1 - 2.3e-18 66.8 0.0 2.3e-18 66.8 0.0 3.1 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 CBY16145.1 - 6.7e-11 42.4 9.6 6.7e-11 42.4 9.6 4.3 2 1 2 4 4 4 2 Flotillin RFC1 PF08519.12 CBY16147.1 - 7e-47 159.5 0.1 2.5e-46 157.7 0.0 1.9 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain PH PF00169.29 CBY16148.1 - 1.8e-08 34.8 0.1 7.6e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 CBY16148.1 - 0.001 19.4 0.2 0.072 13.5 0.0 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain IMS_C PF11799.8 CBY16149.1 - 9.5e-15 55.3 0.0 2.6e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain GAPT PF11770.8 CBY16149.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.1 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) UQ_con PF00179.26 CBY16150.1 - 8.5e-24 83.8 0.0 9.3e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RIIa PF02197.17 CBY16151.1 - 2.2e-05 24.0 0.0 4.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 CBY16151.1 - 6.8e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif PASTA PF03793.19 CBY16151.1 - 0.015 15.1 0.1 0.042 13.7 0.0 1.8 2 0 0 2 2 2 0 PASTA domain Glyco_hydro_47 PF01532.20 CBY16152.1 - 8.6e-70 235.9 0.0 9.4e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Galactosyl_T PF01762.21 CBY16153.1 - 5.5e-05 23.1 0.0 6.2e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase RasGAP PF00616.19 CBY16154.1 - 0.097 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Pkinase PF00069.25 CBY16156.1 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY16156.1 - 3.6e-05 23.2 0.0 0.0002 20.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase dCMP_cyt_deam_1 PF00383.23 CBY16157.1 - 1.3e-27 95.6 0.0 1.8e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBY16157.1 - 7.8e-14 51.6 0.0 9.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CBY16157.1 - 0.011 15.7 0.1 0.046 13.8 0.0 1.8 1 1 1 2 2 2 0 Bd3614-like deaminase His_Me_b4a2 PF18275.1 CBY16157.1 - 0.07 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain APOBEC3 PF18771.1 CBY16157.1 - 0.097 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 ATP-synt_C PF00137.21 CBY16158.1 - 8.6e-26 90.1 40.1 4.9e-15 55.6 13.4 2.7 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 CBY16158.1 - 2 8.9 3.2 1.6 9.2 0.2 2.3 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF3083 PF11281.8 CBY16160.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) CytochromB561_N PF09786.9 CBY16162.1 - 0.15 11.0 1.6 0.15 11.1 1.6 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Dimer_Tnp_hAT PF05699.14 CBY16163.1 - 1.6e-07 31.0 0.2 2.9e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Thioredoxin PF00085.20 CBY16164.1 - 4.7e-07 29.8 0.1 6.1e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBY16164.1 - 0.0017 17.8 0.1 0.0021 17.5 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 CBY16164.1 - 0.029 14.1 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 CBY16164.1 - 0.047 13.6 0.0 0.055 13.4 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Serpin PF00079.20 CBY16165.1 - 1.7e-56 192.1 0.4 2.3e-56 191.7 0.4 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sulfotransfer_4 PF17784.1 CBY16166.1 - 0.0024 17.8 0.0 0.0038 17.1 0.0 1.4 2 0 0 2 2 2 1 Sulfotransferase domain PDZ PF00595.24 CBY16168.1 - 2.2e-11 43.9 2.9 4.2e-11 43.0 2.9 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY16168.1 - 1e-06 28.5 0.7 1.9e-06 27.6 0.7 1.5 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 CBY16168.1 - 1.2e-06 28.1 0.0 3.7e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY16168.1 - 0.0015 18.1 0.2 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 SH3 domain PDZ_2 PF13180.6 CBY16168.1 - 0.0021 18.3 2.3 0.0032 17.8 1.0 2.1 2 1 0 2 2 2 1 PDZ domain Ydc2-catalyt PF09159.10 CBY16168.1 - 1.7 8.3 8.0 6 6.5 2.5 3.0 2 1 0 3 3 3 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Na_Ca_ex PF01699.24 CBY16169.1 - 4.4e-48 163.1 38.2 5.5e-27 94.6 14.7 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein VSP PF03302.13 CBY16169.1 - 0.36 9.6 1.4 0.59 8.9 1.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein PAZ PF02170.22 CBY16170.1 - 7e-14 51.8 0.0 1.6e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CBY16170.1 - 1.5e-07 30.9 0.0 3.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain Piwi PF02171.17 CBY16170.1 - 1.3e-06 27.9 0.0 2.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Piwi domain PRODH PF18327.1 CBY16170.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain Piwi PF02171.17 CBY16171.1 - 6.7e-61 206.2 0.0 7.8e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Piwi domain STAG PF08514.11 CBY16171.1 - 0.026 14.4 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 STAG domain Kelch_2 PF07646.15 CBY16172.1 - 0.043 13.8 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Kelch motif DUF3010 PF11215.8 CBY16173.1 - 0.067 13.5 0.1 0.086 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) Sema PF01403.19 CBY16174.1 - 5.8e-12 45.2 0.6 7.7e-12 44.7 0.6 1.1 1 0 0 1 1 1 1 Sema domain Pkinase PF00069.25 CBY16176.1 - 0.00019 20.9 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain BCD PF15461.6 CBY16176.1 - 0.00089 18.8 0.5 0.0013 18.3 0.5 1.5 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase PIG-Y PF15159.6 CBY16176.1 - 1.3 10.0 6.3 5 8.1 6.3 2.0 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y IHHNV_capsid PF16530.5 CBY16182.1 - 0.044 12.9 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid WD40 PF00400.32 CBY16185.1 - 2.2e-17 63.1 4.0 0.00022 22.0 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY16185.1 - 2e-11 44.0 0.4 0.0056 16.9 0.1 5.0 3 3 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY16185.1 - 1.6e-07 31.0 0.0 0.00054 19.4 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CBY16185.1 - 6.1e-05 21.9 0.2 1.2 7.7 0.0 4.1 5 0 0 5 5 5 2 Nucleoporin Nup120/160 IKI3 PF04762.12 CBY16185.1 - 0.0017 16.5 0.0 0.0022 16.1 0.0 1.3 1 0 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.5 CBY16185.1 - 0.048 12.6 0.0 20 4.0 0.0 3.8 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Utp8 PF10395.9 CBY16185.1 - 0.27 9.7 0.1 1.3 7.4 0.0 1.8 1 1 0 2 2 2 0 Utp8 family NFACT-C PF11923.8 CBY16187.1 - 2.1e-25 88.7 0.0 2.1e-25 88.7 0.0 3.2 2 1 1 3 3 3 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 CBY16187.1 - 5.7e-12 46.3 0.1 1.1e-11 45.3 0.1 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain PDZ_6 PF17820.1 CBY16188.1 - 1.7e-08 34.2 0.0 4.6e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY16188.1 - 2.2e-07 31.1 0.0 1.2e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CBY16188.1 - 3.2e-05 24.2 0.0 0.00054 20.2 0.0 2.5 2 0 0 2 2 2 1 PDZ domain DnaJ PF00226.31 CBY16188.1 - 0.26 11.4 4.6 8.9 6.5 0.0 3.3 3 0 0 3 3 3 0 DnaJ domain RINT1_TIP1 PF04437.13 CBY16191.1 - 4.6e-23 81.9 15.8 7.4e-22 77.9 15.8 2.5 1 1 0 1 1 1 1 RINT-1 / TIP-1 family DnaJ PF00226.31 CBY16192.1 - 8.2e-14 51.5 0.1 1.3e-13 50.8 0.1 1.4 1 1 0 1 1 1 1 DnaJ domain Cytochrome_C7 PF14522.6 CBY16192.1 - 0.17 11.9 3.5 0.49 10.4 3.5 1.8 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Yippee-Mis18 PF03226.14 CBY16196.1 - 2e-12 47.3 0.3 2.6e-12 46.9 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 CBY16196.1 - 0.0051 16.9 0.6 0.0082 16.2 0.6 1.3 1 0 0 1 1 1 1 SelR domain HNH_5 PF14279.6 CBY16196.1 - 0.038 13.8 0.4 0.94 9.4 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease RIG-I_C-RD PF11648.8 CBY16196.1 - 0.042 14.1 2.3 0.05 13.8 1.1 1.7 2 1 0 2 2 2 0 C-terminal domain of RIG-I HECT_2 PF09814.9 CBY16196.1 - 0.051 12.4 0.5 0.17 10.7 0.5 1.8 1 1 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.7 CBY16196.1 - 0.15 12.1 1.9 4.8 7.3 2.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF4606 PF15379.6 CBY16196.1 - 0.19 12.0 1.3 0.38 11.0 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) DUF1619 PF07773.11 CBY16197.1 - 4.4e-22 79.4 29.3 2e-20 73.9 23.1 3.4 2 2 0 2 2 2 2 Protein of unknown function (DUF1619) O-FucT PF10250.9 CBY16198.1 - 6.4e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Smg4_UPF3 PF03467.15 CBY16199.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family Ribosomal_S13_N PF08069.12 CBY16201.1 - 3.2e-29 100.8 0.3 5e-29 100.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CBY16201.1 - 1.4e-13 50.8 0.1 2.4e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_L5_C PF00673.21 CBY16202.1 - 7.1e-20 71.0 0.0 1.3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CBY16202.1 - 1.7e-19 69.9 0.1 5.2e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L26 PF16906.5 CBY16203.1 - 1.1e-39 134.7 2.8 1.5e-39 134.3 2.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CBY16203.1 - 2.3e-07 30.5 1.7 4.4e-07 29.6 1.7 1.5 1 0 0 1 1 1 1 KOW motif Ribosomal_S10 PF00338.22 CBY16204.1 - 5.8e-25 87.4 0.4 6.9e-25 87.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e UB2H PF14814.6 CBY16204.1 - 0.04 13.9 0.4 3.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain Sulfotransfer_4 PF17784.1 CBY16205.1 - 6.8e-24 84.9 0.1 9.6e-24 84.4 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain PapD_C PF02753.17 CBY16206.1 - 0.22 11.9 1.5 0.41 11.0 0.1 2.0 2 1 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain Mtp PF03821.16 CBY16207.1 - 3.7e-05 23.4 2.3 6.8e-05 22.6 2.3 1.4 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter Shisa PF13908.6 CBY16207.1 - 0.011 16.0 0.2 0.011 16.0 0.2 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tmemb_9 PF05434.11 CBY16207.1 - 0.036 14.0 0.4 0.036 14.0 0.4 1.8 2 0 0 2 2 2 0 TMEM9 DUF2207 PF09972.9 CBY16207.1 - 0.037 12.8 0.0 0.037 12.8 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) OAD_gamma PF04277.13 CBY16207.1 - 0.047 14.3 0.2 0.047 14.3 0.2 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF1418 PF07214.12 CBY16207.1 - 0.068 13.0 5.7 0.13 12.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Patched PF02460.18 CBY16207.1 - 0.074 11.1 8.2 0.14 10.2 8.2 1.4 1 0 0 1 1 1 0 Patched family SHP PF03579.13 CBY16207.1 - 0.14 12.1 5.0 2.8 8.0 0.1 3.5 3 0 0 3 3 3 0 Small hydrophobic protein DUF2569 PF10754.9 CBY16207.1 - 0.2 12.1 0.2 0.2 12.1 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) Pex24p PF06398.11 CBY16207.1 - 0.23 10.4 5.3 0.31 10.0 4.5 1.7 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Phage_holin_2_4 PF16082.5 CBY16207.1 - 0.27 11.0 0.8 0.78 9.5 0.8 1.7 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like HemY_N PF07219.13 CBY16207.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.5 3 1 0 4 4 4 0 HemY protein N-terminus DUF2631 PF10939.8 CBY16207.1 - 2.6 8.0 6.6 3.2 7.7 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) Acyltransferase PF01553.21 CBY16209.1 - 5.2e-17 61.7 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CBY16209.1 - 1.9e-07 31.1 0.1 4.6e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF4299 PF14132.6 CBY16209.1 - 0.033 13.6 0.1 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4299) DUF2207 PF09972.9 CBY16209.1 - 0.04 12.7 0.2 0.05 12.4 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PHD PF00628.29 CBY16210.1 - 6.9e-12 45.1 4.9 2e-11 43.6 4.9 1.9 1 0 0 1 1 1 1 PHD-finger zf-RanBP PF00641.18 CBY16210.1 - 0.00012 21.3 8.8 0.0032 16.7 1.8 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others PHD_2 PF13831.6 CBY16210.1 - 0.006 16.1 1.9 0.006 16.1 1.9 2.3 2 0 0 2 2 2 1 PHD-finger Rubredoxin PF00301.20 CBY16210.1 - 0.023 14.7 5.9 0.82 9.7 0.3 2.6 2 0 0 2 2 2 0 Rubredoxin ATG11 PF10377.9 CBY16210.1 - 0.085 12.9 0.3 0.085 12.9 0.3 3.2 3 1 0 3 3 3 0 Autophagy-related protein 11 zf-RING_2 PF13639.6 CBY16210.1 - 1.9 8.9 4.9 2.7 8.4 4.0 1.8 2 0 0 2 2 2 0 Ring finger domain zinc_ribbon_10 PF10058.9 CBY16210.1 - 2 8.2 5.4 14 5.5 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD_4 PF16866.5 CBY16210.1 - 8.3 6.6 8.3 27 4.9 0.1 3.3 2 1 0 2 2 2 0 PHD-finger ASC PF00858.24 CBY16211.1 - 1.1e-29 103.7 19.3 1.9e-29 102.9 19.3 1.3 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel IL7 PF01415.16 CBY16211.1 - 1.9 8.5 6.6 5.9 6.9 2.2 2.3 2 0 0 2 2 2 0 Interleukin 7/9 family Endomucin PF07010.12 CBY16214.1 - 0.017 15.1 0.1 0.019 15.0 0.1 1.1 1 0 0 1 1 1 0 Endomucin STE3 PF02076.15 CBY16214.1 - 0.049 12.8 0.1 0.061 12.5 0.1 1.1 1 0 0 1 1 1 0 Pheromone A receptor DSBA PF01323.20 CBY16215.1 - 3.2e-38 131.5 0.0 3.6e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Las1 PF04031.13 CBY16217.1 - 1.3e-13 51.4 0.4 3.7e-13 49.9 0.4 1.8 1 0 0 1 1 1 1 Las1-like DUF2315 PF10231.9 CBY16217.1 - 0.00088 19.4 0.1 0.00088 19.4 0.1 2.1 2 0 0 2 2 2 1 Apoptogenic protein 1 Patched PF02460.18 CBY16217.1 - 0.49 8.4 4.8 0.86 7.6 0.2 2.1 2 0 0 2 2 2 0 Patched family Roc PF08477.13 CBY16218.1 - 6e-05 23.2 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY16218.1 - 0.00026 20.5 0.0 0.0024 17.3 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBY16218.1 - 0.0033 16.6 0.9 0.0058 15.8 0.9 1.4 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 CBY16218.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Apt1 PF10351.9 CBY16219.1 - 0.054 12.4 8.7 0.075 11.9 8.7 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 CBY16219.1 - 5.4 6.9 17.7 8.2 6.3 17.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Kelch_5 PF13854.6 CBY16220.1 - 0.056 13.5 0.7 0.23 11.5 0.1 2.4 2 0 0 2 2 2 0 Kelch motif BTB_2 PF02214.22 CBY16221.1 - 2.9e-24 85.3 0.0 4.9e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CBY16221.1 - 0.0021 18.2 0.0 0.005 16.9 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain NusA_N PF08529.11 CBY16223.1 - 0.0055 17.0 0.6 0.0068 16.8 0.6 1.2 1 0 0 1 1 1 1 NusA N-terminal domain DUF4579 PF15158.6 CBY16225.1 - 3.4e-72 242.1 3.1 4.2e-72 241.8 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4579) TMEM251 PF15190.6 CBY16225.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 251 Galactosyl_T PF01762.21 CBY16226.1 - 9e-14 51.7 0.0 1.2e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase MFS_1 PF07690.16 CBY16228.1 - 1.7e-30 106.2 11.0 2.1e-30 105.9 11.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 CBY16228.1 - 0.0012 18.2 4.6 0.0023 17.3 4.6 1.4 1 0 0 1 1 1 1 Sporulation factor SpoIIGA YhhN PF07947.14 CBY16228.1 - 0.021 14.4 5.1 0.02 14.5 3.1 2.0 1 1 1 2 2 2 0 YhhN family Baculo_E25 PF05274.11 CBY16228.1 - 0.026 14.4 0.1 0.042 13.7 0.1 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 FXa_inhibition PF14670.6 CBY16229.1 - 0.001 19.3 13.5 0.0037 17.5 9.0 2.5 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site VWA PF00092.28 CBY16229.1 - 0.0064 16.8 0.0 0.0081 16.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain SLR1-BP PF07333.12 CBY16229.1 - 0.025 15.0 7.8 0.025 15.0 7.8 1.7 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) AAA PF00004.29 CBY16230.1 - 2.5e-18 66.8 0.0 4.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY16230.1 - 0.00034 21.1 0.4 0.0084 16.5 0.4 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CBY16230.1 - 0.0057 15.8 0.0 0.0085 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CBY16230.1 - 0.0084 16.7 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBY16230.1 - 0.025 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBY16230.1 - 0.032 14.7 0.0 0.066 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY16230.1 - 0.033 13.9 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CBY16230.1 - 0.041 14.4 0.0 0.12 12.9 0.0 1.6 1 1 0 2 2 2 0 ABC transporter RuvB_N PF05496.12 CBY16230.1 - 0.053 13.3 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBY16230.1 - 0.079 13.2 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 CBY16230.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 CBY16230.1 - 0.095 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY16230.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CBY16230.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 CBY16230.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBY16230.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.7 2 0 0 2 2 1 0 RNA helicase RsgA_GTPase PF03193.16 CBY16230.1 - 0.14 12.0 0.4 2.1 8.2 0.0 2.5 1 1 2 3 3 3 0 RsgA GTPase DUF4615 PF15393.6 CBY16231.1 - 3.2e-29 102.3 5.5 3.7e-29 102.1 5.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4615) Rhomboid PF01694.22 CBY16232.1 - 1.3e-27 96.7 4.5 1.3e-27 96.7 4.5 2.6 3 0 0 3 3 3 2 Rhomboid family VanZ PF04892.12 CBY16232.1 - 1.4 9.6 7.2 0.11 13.1 0.9 2.4 1 1 1 2 2 2 0 VanZ like family La PF05383.17 CBY16233.1 - 5.3e-20 71.2 0.1 8.3e-20 70.6 0.1 1.3 1 0 0 1 1 1 1 La domain Abhydrolase_6 PF12697.7 CBY16236.1 - 9.8e-11 42.7 0.0 1.3e-10 42.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBY16236.1 - 1.1e-09 38.3 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBY16236.1 - 4.6e-08 32.6 0.0 1.2e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CBY16236.1 - 3e-05 24.3 0.0 0.00013 22.2 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.7 CBY16236.1 - 8.3e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CBY16236.1 - 0.038 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 CBY16236.1 - 0.05 13.2 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 CBY16236.1 - 0.08 12.8 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Chlorophyllase2 PF12740.7 CBY16236.1 - 0.14 11.1 0.0 0.28 10.1 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Acetyltransf_1 PF00583.25 CBY16237.1 - 0.0002 21.6 0.0 0.00028 21.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY16237.1 - 0.00074 19.5 0.0 0.00092 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY16237.1 - 0.0014 19.1 0.1 0.0027 18.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY16237.1 - 0.0033 17.5 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 CBY16237.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 CBY16237.1 - 0.028 14.4 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Kinesin PF00225.23 CBY16238.1 - 9.4e-40 136.5 0.0 1e-39 136.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY16238.1 - 1.3e-22 80.3 0.0 1.5e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding Peptidase_M1 PF01433.20 CBY16239.1 - 9.3e-45 152.9 3.2 1.6e-44 152.1 3.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY16239.1 - 6.2e-27 95.0 0.0 1e-26 94.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Galactosyl_T PF01762.21 CBY16240.1 - 2.9e-32 112.1 0.1 4e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase RAB3GAP2_C PF14656.6 CBY16241.1 - 2.4e-06 26.1 0.2 3e-06 25.8 0.2 1.0 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus AMP-binding PF00501.28 CBY16243.1 - 9.2e-25 87.1 0.6 1.1e-24 86.8 0.6 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY16243.1 - 1.6e-16 61.0 0.1 2.7e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3586 PF12131.8 CBY16244.1 - 0.013 15.7 9.5 0.5 10.6 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3586) Sushi PF00084.20 CBY16244.1 - 5.8 7.6 16.1 0.12 13.0 5.1 3.3 2 1 1 3 3 3 0 Sushi repeat (SCR repeat) ETRAMP PF09716.10 CBY16246.1 - 0.055 13.5 0.4 0.095 12.8 0.0 1.8 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Cation_ATPase_C PF00689.21 CBY16246.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus RhoGAP PF00620.27 CBY16248.1 - 4.8e-25 88.2 0.0 7.2e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain UQ_con PF00179.26 CBY16249.1 - 2.5e-47 160.0 0.0 2.8e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rootletin PF15035.6 CBY16250.1 - 0.028 14.4 3.4 0.042 13.9 3.4 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PP2C_C PF07830.13 CBY16250.1 - 0.27 11.7 1.8 0.66 10.5 1.8 1.7 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Haspin_kinase PF12330.8 CBY16251.1 - 4.5e-42 144.3 0.0 5.7e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 CBY16251.1 - 0.00019 20.9 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CBY16251.1 - 0.00022 21.2 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY16251.1 - 0.00044 19.9 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CBY16251.1 - 0.0017 17.8 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CBY16251.1 - 0.004 16.5 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 CBY16254.1 - 2.7e-08 33.6 0.2 3.4e-08 33.2 0.2 1.2 1 0 0 1 1 1 1 Ras family IF3_N PF05198.16 CBY16254.1 - 0.049 13.9 0.1 0.049 13.9 0.1 1.7 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain Elf1 PF05129.13 CBY16255.1 - 2.7e-30 104.2 2.2 3e-30 104.1 2.2 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 CBY16255.1 - 0.029 14.3 2.2 0.053 13.5 2.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Cys_rich_CPXG PF14255.6 CBY16255.1 - 0.033 14.1 4.8 0.74 9.8 0.6 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG Rubredoxin PF00301.20 CBY16255.1 - 0.039 14.0 1.5 0.039 14.0 1.5 2.1 2 0 0 2 2 2 0 Rubredoxin Lar_restr_allev PF14354.6 CBY16255.1 - 0.043 14.2 3.4 0.055 13.9 3.4 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-Di19 PF05605.12 CBY16255.1 - 3.6 8.0 8.6 28 5.1 8.6 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Prefoldin_2 PF01920.20 CBY16256.1 - 2.1e-16 59.8 5.9 2.6e-16 59.5 5.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit LOH1CR12 PF10158.9 CBY16256.1 - 0.023 14.7 1.5 4.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Tumour suppressor protein Prefoldin PF02996.17 CBY16256.1 - 0.21 11.5 5.0 0.16 11.9 2.0 2.2 2 1 0 2 2 2 0 Prefoldin subunit Spc24 PF08286.11 CBY16256.1 - 1.2 9.4 7.2 0.54 10.5 0.7 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 SH3_9 PF14604.6 CBY16257.1 - 2e-06 27.5 0.0 3.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY16257.1 - 2.2e-05 24.0 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain TSP_C PF05735.12 CBY16260.1 - 1.4e-89 299.3 0.4 2e-89 298.8 0.4 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 CBY16260.1 - 4.2e-30 103.1 104.3 5.3e-15 54.8 13.1 7.9 7 1 1 8 8 8 7 Thrombospondin type 3 repeat EGF_3 PF12947.7 CBY16260.1 - 0.00015 21.8 20.2 0.0031 17.7 9.0 3.0 2 0 0 2 2 2 2 EGF domain EGF_CA PF07645.15 CBY16260.1 - 0.0016 18.6 5.8 0.0016 18.6 5.8 3.7 2 1 1 3 3 3 1 Calcium-binding EGF domain DUF5531 PF17671.1 CBY16260.1 - 0.2 11.5 0.2 0.38 10.6 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5531) Holin_9 PF16936.5 CBY16263.1 - 0.04 14.1 0.4 0.056 13.6 0.4 1.3 1 0 0 1 1 1 0 Putative holin Tex_YqgF PF16921.5 CBY16265.1 - 1.1e-34 119.6 0.0 3.6e-34 117.9 0.0 1.9 2 0 0 2 2 2 1 Tex protein YqgF-like domain Tex_N PF09371.10 CBY16265.1 - 1.8e-21 76.6 5.6 3.7e-21 75.6 5.6 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.7 CBY16265.1 - 9.5e-20 70.6 2.0 1.7e-19 69.8 0.2 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_9 PF17674.1 CBY16265.1 - 2.5e-11 44.3 1.7 6.6e-11 43.0 0.1 2.6 2 0 0 2 2 2 1 HHH domain YqgF PF14639.6 CBY16265.1 - 3.4e-10 39.9 0.5 1.2e-09 38.1 0.0 2.2 2 1 1 3 3 3 1 Holliday-junction resolvase-like of SPT6 S1 PF00575.23 CBY16265.1 - 2e-08 34.5 0.1 5.2e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HHH_6 PF14579.6 CBY16265.1 - 0.004 17.4 0.2 0.035 14.4 0.1 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_7 PF14635.6 CBY16265.1 - 0.015 15.6 0.0 0.065 13.6 0.0 2.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 CBY16265.1 - 0.091 13.4 0.9 1.9 9.2 0.4 3.4 3 1 0 3 3 2 0 Helix-hairpin-helix domain TMPIT PF07851.13 CBY16265.1 - 0.65 9.2 2.6 1.2 8.3 2.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Com_YlbF PF06133.11 CBY16265.1 - 4.1 8.1 10.9 0.67 10.6 3.9 2.9 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA MAM33 PF02330.16 CBY16266.1 - 2e-12 47.5 1.0 6.7e-12 45.8 1.0 1.8 1 1 0 1 1 1 1 Mitochondrial glycoprotein Lysine_decarbox PF03641.14 CBY16266.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Possible lysine decarboxylase fn3_PAP PF17808.1 CBY16268.1 - 0.027 14.6 0.1 0.029 14.5 0.1 1.2 1 1 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Amino_oxidase PF01593.24 CBY16269.1 - 3.9e-14 52.8 0.0 4.5e-10 39.4 0.0 2.3 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CBY16269.1 - 9e-12 45.1 0.1 1.6e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Prenylcys_lyase PF07156.14 CBY16269.1 - 0.0059 15.7 0.1 0.0092 15.1 0.1 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase DAO PF01266.24 CBY16269.1 - 0.0097 15.5 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CBY16269.1 - 0.05 13.6 0.1 6.2 6.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Terminase_3 PF04466.13 CBY16269.1 - 0.064 12.8 0.4 0.17 11.4 0.2 1.7 1 1 1 2 2 2 0 Phage terminase large subunit Pyr_redox_2 PF07992.14 CBY16269.1 - 0.11 11.8 0.4 0.25 10.5 0.4 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY16269.1 - 0.11 11.8 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 CBY16269.1 - 0.12 12.9 0.6 1.2 9.7 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Nsp3_PL2pro PF12124.8 CBY16269.1 - 0.13 12.1 0.1 41 4.1 0.0 3.1 3 0 0 3 3 3 0 Coronavirus polyprotein cleavage domain FAD_binding_2 PF00890.24 CBY16269.1 - 0.17 10.9 0.1 0.28 10.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain S1 PF00575.23 CBY16271.1 - 5.1e-10 39.6 0.2 8.3e-10 38.9 0.2 1.3 1 1 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 CBY16271.1 - 0.0097 16.0 0.0 0.018 15.1 0.0 1.5 1 1 1 2 2 2 1 S1 domain Methyltrn_RNA_3 PF02598.17 CBY16271.1 - 0.049 13.1 0.0 0.055 13.0 0.0 1.0 1 0 0 1 1 1 0 Putative RNA methyltransferase Ig_3 PF13927.6 CBY16272.1 - 4.1e-24 85.0 1.1 6.5e-12 45.9 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 CBY16272.1 - 4.8e-22 77.8 0.0 9.3e-11 41.7 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY16272.1 - 5.5e-13 49.1 2.9 2.5e-07 30.9 0.0 4.7 5 1 0 5 5 5 3 Immunoglobulin domain ig PF00047.25 CBY16272.1 - 1.5e-12 47.5 0.1 1.8e-06 28.0 0.0 3.9 5 0 0 5 5 5 2 Immunoglobulin domain V-set PF07686.17 CBY16272.1 - 2.7e-08 33.9 0.6 0.015 15.5 0.0 4.8 4 1 0 4 4 4 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CBY16272.1 - 9.9e-07 28.7 0.1 0.061 13.4 0.0 3.2 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 CBY16272.1 - 0.0029 17.6 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 CBY16272.1 - 0.017 15.4 0.5 9.5 6.6 0.0 3.0 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Tfb2_C PF18307.1 CBY16273.1 - 0.0099 16.3 0.1 0.027 14.9 0.0 1.8 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain GalKase_gal_bdg PF10509.9 CBY16277.1 - 4.3e-23 80.6 0.0 8.5e-23 79.7 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CBY16277.1 - 4.6e-12 46.1 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CBY16277.1 - 9.6e-09 35.4 0.2 2.5e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Myotub-related PF06602.14 CBY16278.1 - 3.1e-51 174.4 1.5 3.1e-51 174.4 1.5 1.4 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 CBY16278.1 - 0.024 14.2 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-BED PF02892.15 CBY16278.1 - 0.025 14.6 0.3 0.056 13.5 0.3 1.6 1 0 0 1 1 1 0 BED zinc finger DSPc PF00782.20 CBY16278.1 - 0.025 14.4 1.2 0.039 13.8 0.1 1.9 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain PrlF_antitoxin PF15937.5 CBY16278.1 - 0.066 13.7 0.0 0.19 12.2 0.0 1.7 2 0 0 2 2 2 0 prlF antitoxin for toxin YhaV_toxin Shugoshin_N PF07558.11 CBY16278.1 - 0.11 12.4 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region SlyX PF04102.12 CBY16278.1 - 0.12 13.0 0.4 0.22 12.2 0.4 1.3 1 0 0 1 1 1 0 SlyX Herpes_UL14 PF03580.14 CBY16278.1 - 0.13 12.5 0.2 0.21 11.8 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Carb_anhydrase PF00194.21 CBY16279.1 - 9.2e-72 241.6 0.0 1.1e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Macoilin PF09726.9 CBY16280.1 - 0.44 9.0 16.3 0.46 9.0 16.3 1.0 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 CBY16280.1 - 0.96 8.0 24.2 1.2 7.7 24.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TMEM237 PF15383.6 CBY16280.1 - 2.2 7.3 8.7 2.7 7.0 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 Nop53 PF07767.11 CBY16281.1 - 4.1e-39 135.1 20.8 4.1e-39 135.1 20.8 2.0 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) FSA_C PF10479.9 CBY16282.1 - 0.024 12.8 10.4 0.03 12.5 10.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 CBY16282.1 - 0.057 13.4 42.0 0.11 12.5 42.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein NUC194 PF08163.12 CBY16282.1 - 0.3 10.0 4.7 0.44 9.4 4.7 1.1 1 0 0 1 1 1 0 NUC194 domain DUF572 PF04502.13 CBY16282.1 - 1.2 8.7 18.6 1.7 8.2 18.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) UPAR_LY6 PF00021.21 CBY16282.1 - 3.1 8.6 13.1 0.12 13.1 5.9 2.2 2 0 0 2 2 2 0 u-PAR/Ly-6 domain Peptidase_S64 PF08192.11 CBY16282.1 - 7.2 5.0 11.6 9.3 4.6 11.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 MRP-S31 PF15433.6 CBY16282.1 - 9.1 5.8 11.5 9.8 5.7 11.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Sulfotransfer_4 PF17784.1 CBY16284.1 - 2.6e-48 164.7 0.1 3.3e-48 164.4 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY16284.1 - 0.0038 17.6 0.1 0.068 13.5 0.0 2.4 1 1 0 2 2 2 1 Sulfotransferase family PatG_C PF18065.1 CBY16284.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 PatG C-terminal Mito_carr PF00153.27 CBY16285.1 - 1.1e-53 179.1 2.8 1.6e-18 66.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein EutK_C PF16365.5 CBY16285.1 - 0.013 15.5 0.1 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus zf-C3HC4_3 PF13920.6 CBY16286.1 - 3.9e-05 23.4 6.4 3.9e-05 23.4 6.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY16286.1 - 0.0013 18.7 8.2 0.0013 18.7 8.2 3.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY16286.1 - 0.0023 18.2 9.2 0.0023 18.2 9.2 2.5 2 0 0 2 2 2 1 Ring finger domain DZR PF12773.7 CBY16286.1 - 0.012 15.6 7.0 0.012 15.6 7.0 3.3 3 1 1 4 4 4 0 Double zinc ribbon V_ATPase_I PF01496.19 CBY16286.1 - 0.013 13.4 8.0 0.016 13.2 8.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C3HC4 PF00097.25 CBY16286.1 - 0.038 13.9 9.1 0.038 13.9 9.1 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2256 PF10013.9 CBY16286.1 - 0.049 13.7 0.2 0.049 13.7 0.2 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_UBOX PF13445.6 CBY16286.1 - 0.069 13.2 10.5 3 8.0 4.3 3.4 2 1 0 2 2 2 0 RING-type zinc-finger DUF2381 PF09544.10 CBY16286.1 - 0.17 11.4 4.5 0.22 11.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Prok-RING_4 PF14447.6 CBY16286.1 - 0.29 11.0 13.6 1.2 9.0 9.0 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY16286.1 - 1.9 8.4 16.1 0.28 11.1 9.4 2.8 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF384 PF04064.13 CBY16287.1 - 0.00079 19.2 1.3 0.00086 19.1 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF384) FAM153 PF15722.5 CBY16287.1 - 0.0099 16.2 0.6 0.011 16.0 0.6 1.1 1 0 0 1 1 1 1 FAM153 family YqzL PF14006.6 CBY16287.1 - 0.37 11.2 2.7 0.98 9.8 2.7 1.7 1 1 0 1 1 1 0 YqzL-like protein FAM76 PF16046.5 CBY16288.1 - 7.1e-75 252.1 30.4 7.9e-75 252.0 30.4 1.0 1 0 0 1 1 1 1 FAM76 protein DUF4834 PF16118.5 CBY16288.1 - 5.2 8.1 5.9 1.2 10.2 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TSP_1 PF00090.19 CBY16292.1 - 1e-41 140.9 132.3 5.2e-10 39.4 9.8 8.8 8 1 0 8 8 8 7 Thrombospondin type 1 domain Forkhead_N PF08430.12 CBY16292.1 - 0.019 15.6 16.3 0.019 15.6 16.3 2.5 2 0 0 2 2 2 0 Forkhead N-terminal region RasGAP PF00616.19 CBY16294.1 - 3.6e-35 121.6 0.0 1.6e-34 119.5 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CBY16295.1 - 1.3e-17 64.2 6.7 1.8e-17 63.7 6.7 1.2 1 0 0 1 1 1 1 RasGAP C-terminus Zona_pellucida PF00100.23 CBY16296.1 - 9.3e-16 58.4 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Yippee-Mis18 PF03226.14 CBY16297.1 - 3.4e-12 46.5 0.3 4.4e-12 46.1 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 CBY16297.1 - 0.0037 17.3 0.5 0.006 16.7 0.5 1.3 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 CBY16297.1 - 0.069 13.4 2.1 0.086 13.1 1.0 1.8 2 1 0 2 2 2 0 C-terminal domain of RIG-I HECT_2 PF09814.9 CBY16297.1 - 0.084 11.7 0.5 0.3 9.9 0.0 1.8 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.7 CBY16297.1 - 0.18 11.9 1.6 1.6 8.8 1.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF4606 PF15379.6 CBY16297.1 - 0.21 11.8 1.0 0.52 10.6 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) zf-CCCH PF00642.24 CBY16298.1 - 0.00056 19.7 2.3 0.0013 18.6 2.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY16298.1 - 0.00059 19.8 2.0 0.00059 19.8 2.0 2.5 4 0 0 4 4 4 1 Zinc finger domain Torus PF16131.5 CBY16298.1 - 0.0023 18.6 0.1 0.0081 16.8 0.1 1.9 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 CBY16298.1 - 0.04 13.7 2.0 0.087 12.6 2.0 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger HEAT PF02985.22 CBY16299.1 - 2.4e-05 24.2 0.4 0.0031 17.6 0.0 2.9 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 CBY16299.1 - 0.0012 19.2 0.1 0.036 14.5 0.2 2.2 1 1 1 2 2 2 2 HEAT repeats CST-I PF06002.12 CBY16299.1 - 0.062 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) Vac14_Fab1_bd PF12755.7 CBY16299.1 - 0.09 13.4 0.1 1.6 9.4 0.1 2.4 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region 7tm_1 PF00001.21 CBY16300.1 - 1.5e-29 103.2 3.1 5.1e-29 101.4 3.1 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CBY16300.1 - 0.26 10.5 9.6 0.54 9.5 9.5 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw MARVEL PF01284.23 CBY16300.1 - 4.5 7.3 9.6 3.8 7.5 2.1 3.1 3 0 0 3 3 3 0 Membrane-associating domain RRM_1 PF00076.22 CBY16301.1 - 0.1 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Presenilin PF01080.17 CBY16302.1 - 6.3 5.4 5.0 8.4 5.0 5.0 1.2 1 0 0 1 1 1 0 Presenilin HLH PF00010.26 CBY16303.1 - 8.8e-15 54.4 0.6 2.4e-14 53.0 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UBA2_C PF16195.5 CBY16304.1 - 0.43 11.3 3.7 2.3 9.0 0.0 3.0 2 1 1 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus AAA_6 PF12774.7 CBY16305.1 - 4.3e-17 62.1 0.0 4.5e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region SNARE PF05739.19 CBY16306.1 - 0.13 12.3 1.0 6.6 6.8 0.4 2.1 2 0 0 2 2 2 0 SNARE domain FAM76 PF16046.5 CBY16309.1 - 0.014 14.7 0.4 0.025 13.9 0.4 1.3 1 0 0 1 1 1 0 FAM76 protein HPPK PF01288.20 CBY16309.1 - 0.087 13.3 0.0 0.36 11.4 0.0 2.1 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Fez1 PF06818.15 CBY16309.1 - 0.24 11.8 3.3 0.5 10.8 3.3 1.5 1 0 0 1 1 1 0 Fez1 DUF4200 PF13863.6 CBY16309.1 - 4.2 7.8 8.3 1.6 9.2 5.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Sulfatase PF00884.23 CBY16310.1 - 1.1e-34 120.2 0.1 1.4e-34 119.9 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Utp14 PF04615.13 CBY16313.1 - 2.6 6.5 15.2 3.1 6.3 15.2 1.0 1 0 0 1 1 1 0 Utp14 protein PA26 PF04636.13 CBY16313.1 - 9.3 5.0 11.0 11 4.8 11.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Pkinase_Tyr PF07714.17 CBY16314.1 - 4.9e-53 180.1 0.0 8.4e-53 179.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY16314.1 - 2.4e-27 96.0 0.0 2.8e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY16314.1 - 0.0013 17.6 0.2 0.0022 16.9 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY16314.1 - 0.0098 15.2 0.2 0.029 13.7 0.3 1.9 1 1 0 1 1 1 1 Kinase-like SH2 PF00017.24 CBY16315.1 - 1.5e-14 53.8 0.0 2.8e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Pkinase_Tyr PF07714.17 CBY16315.1 - 1.8e-09 37.3 0.1 2.7e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY16315.1 - 1.3e-06 28.0 0.1 2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain MIG-14_Wnt-bd PF06664.12 CBY16320.1 - 1.1e-09 37.9 0.2 2.1e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Fas_alpha_ACP PF18325.1 CBY16322.1 - 0.17 12.2 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain C2 PF00168.30 CBY16324.1 - 0.0022 18.3 0.0 0.0023 18.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 CBY16325.1 - 0.0067 16.5 5.5 0.0075 16.3 5.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4366 PF14283.6 CBY16325.1 - 0.036 14.1 0.0 0.12 12.5 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CBY16325.1 - 0.091 11.5 1.4 0.11 11.2 1.4 1.1 1 0 0 1 1 1 0 Presenilin DUF4770 PF15994.5 CBY16325.1 - 0.23 11.7 7.4 0.35 11.1 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF3464 PF11947.8 CBY16325.1 - 0.33 10.7 2.9 11 5.7 4.2 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 TT_ORF2 PF02957.15 CBY16325.1 - 4.2 8.3 6.7 3.6 8.5 3.9 1.9 1 1 1 2 2 2 0 TT viral ORF2 Mrpl_C PF18502.1 CBY16326.1 - 0.068 13.5 0.2 0.07 13.4 0.2 1.1 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain Acetyltransf_13 PF13880.6 CBY16327.1 - 0.0088 16.0 0.2 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase DC_STAMP PF07782.13 CBY16329.1 - 1.7e-12 47.6 0.1 3.6e-12 46.5 0.1 1.5 2 0 0 2 2 2 1 DC-STAMP-like protein Rad17 PF03215.15 CBY16330.1 - 2e-10 40.9 0.1 5e-10 39.6 0.1 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 CBY16330.1 - 0.0099 16.3 0.0 0.048 14.1 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 CBY16330.1 - 0.037 14.4 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_14 PF13173.6 CBY16330.1 - 0.06 13.4 0.0 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBY16330.1 - 0.094 13.2 0.0 0.43 11.1 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 CBY16330.1 - 0.16 12.2 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain YL1 PF05764.13 CBY16330.1 - 2.4 8.2 8.2 0.96 9.5 2.8 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 CBY16330.1 - 5.1 6.7 10.8 0.06 13.1 1.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Methyltransf_25 PF13649.6 CBY16332.1 - 9.7e-12 45.4 0.1 7.3e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY16332.1 - 5.1e-11 42.7 0.0 8.7e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain SNF5 PF04855.12 CBY16332.1 - 1.5e-10 41.3 0.1 3.5e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Methyltransf_12 PF08242.12 CBY16332.1 - 2.6e-10 40.9 0.1 6.9e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY16332.1 - 8.8e-08 32.1 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY16332.1 - 1.9e-07 31.7 0.1 7.1e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CBY16332.1 - 0.0013 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CBY16332.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain ubiquitin PF00240.23 CBY16334.1 - 8.9e-29 99.1 0.2 1e-28 98.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY16334.1 - 5.4e-12 45.4 0.3 6.4e-12 45.1 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBY16334.1 - 4.2e-06 27.1 0.1 1.9e-05 25.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBY16334.1 - 0.0013 18.6 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBY16334.1 - 0.003 17.9 0.1 0.003 17.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBY16334.1 - 0.0042 17.2 0.0 0.0093 16.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBY16334.1 - 0.047 14.3 0.0 0.055 14.0 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 CBY16336.1 - 0.0043 16.8 0.1 0.0048 16.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family ubiquitin PF00240.23 CBY16337.1 - 0.0061 16.3 0.1 0.0071 16.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family ubiquitin PF00240.23 CBY16338.1 - 1.6e-10 40.6 0.1 1.7e-10 40.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY16338.1 - 0.0059 16.4 0.1 0.0059 16.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY16339.1 - 4.6e-79 260.2 11.9 6.7e-34 115.5 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 CBY16339.1 - 9.6e-36 121.5 11.8 6.6e-16 57.9 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBY16339.1 - 6.5e-13 48.9 4.4 0.00014 22.3 0.1 4.1 3 2 0 3 3 3 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CBY16339.1 - 3.1e-08 33.9 0.7 0.01 16.2 0.1 2.4 1 1 1 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CBY16339.1 - 7.6e-08 32.2 0.3 0.015 15.2 0.1 2.4 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Big_7 PF17957.1 CBY16339.1 - 2.3e-07 31.5 0.4 1.4 9.7 0.0 3.2 3 0 0 3 3 3 3 Bacterial Ig domain Rad60-SLD_2 PF13881.6 CBY16339.1 - 2.9e-07 30.6 1.9 0.044 13.9 0.1 3.4 3 2 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBY16339.1 - 2.1e-06 28.2 0.3 0.057 14.0 0.1 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CBY16339.1 - 3.1e-05 23.9 14.8 8.1 6.6 0.2 5.0 5 0 0 5 5 5 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 CBY16339.1 - 5.1e-05 23.2 0.2 0.68 9.7 0.0 2.9 1 1 2 3 3 3 2 Silencing defective 2 N-terminal ubiquitin domain UDP-g_GGTase PF06427.11 CBY16339.1 - 0.00044 20.3 1.8 1.9 8.7 0.0 2.9 3 0 0 3 3 3 2 UDP-glucose:Glycoprotein Glucosyltransferase Big_3_3 PF13750.6 CBY16339.1 - 0.00081 19.1 0.0 11 5.6 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Methyltrans_RNA PF04452.14 CBY16339.1 - 0.001 18.4 1.7 0.32 10.3 0.0 2.4 3 0 0 3 3 3 2 RNA methyltransferase ACT_5 PF13710.6 CBY16339.1 - 0.0037 17.1 1.4 23 4.9 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF3861 PF12977.7 CBY16339.1 - 0.0041 17.3 1.2 5.3 7.3 0.0 3.1 2 1 1 3 3 3 2 Domain of Unknown Function with PDB structure (DUF3861) PDGLE PF13190.6 CBY16339.1 - 0.01 15.7 4.6 7.6 6.5 0.1 3.6 1 1 0 3 3 3 0 PDGLE domain DUF2870 PF11069.8 CBY16339.1 - 0.02 15.2 0.0 15 6.0 0.0 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2870) DUF969 PF06149.12 CBY16339.1 - 0.037 13.5 0.0 7 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 CBY16339.1 - 0.041 14.5 0.4 73 4.1 0.0 3.2 3 0 0 3 3 3 0 ACT domain ORF11CD3 PF10549.9 CBY16339.1 - 0.13 12.4 0.0 46 4.2 0.0 3.2 5 0 0 5 5 2 0 ORF11CD3 domain ProRS-C_2 PF09181.10 CBY16339.1 - 0.42 10.8 3.4 40 4.4 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 CBY16339.1 - 0.6 10.0 4.7 42 4.1 0.1 3.2 3 0 0 3 3 3 0 FlgD Ig-like domain PI3K_p85B PF02192.16 CBY16339.1 - 2.1 8.1 4.3 94 2.8 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain Tash_PEST PF07708.11 CBY16339.1 - 9.4 6.5 6.2 1.4e+02 2.8 0.1 3.3 3 0 0 3 3 3 0 Tash protein PEST motif PKD_channel PF08016.12 CBY16341.1 - 0.00016 20.5 18.6 0.0002 20.2 17.8 1.6 1 1 1 2 2 2 1 Polycystin cation channel Suf PF05843.14 CBY16342.1 - 0.0045 17.0 0.1 0.0045 17.0 0.1 2.4 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) Sec61_beta PF03911.16 CBY16343.1 - 2.1e-20 72.5 0.1 2.6e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Sec61beta family Acatn PF13000.7 CBY16348.1 - 3.6e-26 91.8 21.3 1.8e-24 86.2 19.6 3.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Mucin PF01456.17 CBY16349.1 - 0.00026 21.0 25.9 0.00041 20.4 25.9 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Med3 PF11593.8 CBY16349.1 - 0.065 12.4 21.0 0.085 12.0 21.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ndc1_Nup PF09531.10 CBY16349.1 - 1.4 7.5 3.8 1.6 7.3 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SSP160 PF06933.11 CBY16349.1 - 4.4 5.4 18.6 5.8 5.0 18.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 YL1 PF05764.13 CBY16349.1 - 6.8 6.7 9.8 9.1 6.3 9.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Carn_acyltransf PF00755.20 CBY16350.1 - 3.2e-160 534.6 0.3 3.6e-160 534.4 0.3 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase EOS1 PF12326.8 CBY16350.1 - 7.9 6.4 8.0 8.4 6.3 4.7 2.2 2 0 0 2 2 2 0 N-glycosylation protein SSF PF00474.17 CBY16351.1 - 9.6e-05 21.4 4.8 0.025 13.4 4.7 2.1 1 1 1 2 2 2 2 Sodium:solute symporter family RNA_pol_Rpb1_R PF05001.13 CBY16352.1 - 0.00016 21.9 81.0 0.026 14.9 15.4 6.4 4 1 1 5 5 5 3 RNA polymerase Rpb1 C-terminal repeat YabA PF06156.13 CBY16352.1 - 0.12 13.0 0.8 0.46 11.1 0.5 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF2205 PF10224.9 CBY16352.1 - 0.2 11.7 9.3 0.52 10.3 0.9 3.1 2 1 1 3 3 3 0 Short coiled-coil protein SKA2 PF16740.5 CBY16352.1 - 1.2 9.0 6.6 0.98 9.2 0.1 2.7 2 2 2 4 4 4 0 Spindle and kinetochore-associated protein 2 PhoPQ_related PF10142.9 CBY16356.1 - 9.4e-26 90.3 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Plk4_PB1 PF18190.1 CBY16357.1 - 0.027 14.6 0.1 0.028 14.6 0.1 1.1 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 2OG-FeII_Oxy PF03171.20 CBY16358.1 - 1.1e-15 57.9 0.0 1.9e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBY16358.1 - 4.1e-11 43.7 0.0 7.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2-Hacid_dh_C PF02826.19 CBY16359.1 - 1.6e-49 167.7 0.0 2.3e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CBY16359.1 - 3e-23 82.0 0.0 3.5e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CBY16359.1 - 0.0005 20.3 0.0 0.00091 19.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RVT_1 PF00078.27 CBY16360.1 - 0.00013 21.6 0.0 0.00036 20.1 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 CBY16360.1 - 0.00036 20.1 0.0 0.0015 18.2 0.0 2.0 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RT_RNaseH PF17917.1 CBY16360.1 - 0.027 14.8 0.1 0.75 10.1 0.0 3.0 2 1 0 2 2 2 0 RNase H-like domain found in reverse transcriptase AAA_6 PF12774.7 CBY16361.1 - 1.2e-130 435.3 0.0 1.8e-130 434.7 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CBY16361.1 - 1.8e-21 76.6 2.5 1.7e-15 57.2 0.0 4.1 5 1 0 5 5 3 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY16361.1 - 1.3e-06 28.0 0.1 0.065 12.7 0.0 3.3 3 0 0 3 3 3 2 P-loop containing dynein motor region DHC_N2 PF08393.13 CBY16361.1 - 4.1e-06 26.2 0.0 1.1e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_33 PF13671.6 CBY16361.1 - 1.1e-05 25.6 0.0 0.00099 19.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY16361.1 - 0.00017 22.1 0.0 0.7 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBY16361.1 - 0.00017 21.9 0.0 1.2 9.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CBY16361.1 - 0.00082 19.8 0.0 0.069 13.6 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBY16361.1 - 0.0015 19.1 0.0 2.3 8.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 CBY16361.1 - 0.0028 18.0 0.0 1.3 9.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Dynein_AAA_lid PF17852.1 CBY16361.1 - 0.0062 16.6 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain FtsK_SpoIIIE PF01580.18 CBY16361.1 - 0.0067 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.7 CBY16361.1 - 0.0085 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_30 PF13604.6 CBY16361.1 - 0.014 15.1 0.7 3.9 7.1 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBY16361.1 - 0.019 14.7 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBY16361.1 - 0.031 13.7 0.2 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CBY16361.1 - 0.048 13.4 0.1 0.32 10.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain E2R135 PF11570.8 CBY16361.1 - 0.088 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 AAA_28 PF13521.6 CBY16361.1 - 0.11 12.7 0.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBY16361.1 - 0.12 11.8 0.1 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 CBY16361.1 - 0.21 12.1 0.6 1.6 9.2 0.0 2.7 3 0 0 3 3 3 0 ABC transporter Rtf2 PF04641.12 CBY16362.1 - 1.8e-06 27.5 0.6 1.8e-06 27.5 0.6 2.0 1 1 1 2 2 2 1 Rtf2 RING-finger Laps PF10169.9 CBY16363.1 - 0.0051 17.4 0.2 0.0068 17.0 0.2 1.1 1 0 0 1 1 1 1 Learning-associated protein ENT PF03735.14 CBY16363.1 - 0.021 14.9 0.7 0.034 14.2 0.1 1.7 2 0 0 2 2 2 0 ENT domain ERK-JNK_inhib PF15002.6 CBY16363.1 - 0.16 11.6 2.2 1.1 8.9 0.2 2.0 1 1 1 2 2 2 0 ERK and JNK pathways, inhibitor Zona_pellucida PF00100.23 CBY16364.1 - 4e-12 46.5 0.0 5e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain BRCT_3 PF18428.1 CBY16364.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain SAP PF02037.27 CBY16365.1 - 0.045 13.5 0.8 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 SAP domain PNP_UDP_1 PF01048.20 CBY16366.1 - 6.2e-24 84.5 0.0 7.1e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 CBY16367.1 - 2.4e-26 92.4 0.0 2.8e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Acyl_transf_3 PF01757.22 CBY16368.1 - 0.018 14.1 13.2 0.25 10.4 4.3 2.7 2 1 1 3 3 3 0 Acyltransferase family EF-hand_1 PF00036.32 CBY16369.1 - 1.5e-27 93.0 8.5 2.2e-06 26.8 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY16369.1 - 4.4e-24 82.3 3.7 2.5e-06 26.9 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBY16369.1 - 4.9e-23 81.4 3.9 2.6e-11 43.8 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY16369.1 - 3.2e-20 70.7 7.5 1.3e-05 24.5 0.2 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CBY16369.1 - 8.7e-16 57.5 13.9 0.00017 21.3 1.2 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CBY16369.1 - 2.1e-06 27.6 7.5 0.67 9.9 0.1 4.0 1 1 3 4 4 4 4 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY16369.1 - 1.7e-05 25.1 0.6 0.004 17.4 0.1 2.9 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CBY16369.1 - 0.0036 17.5 7.9 4 7.7 0.2 4.0 2 1 2 4 4 4 3 Dockerin type I domain Lectin_C PF00059.21 CBY16370.1 - 0.0029 18.3 5.5 0.005 17.6 5.5 1.3 1 0 0 1 1 1 1 Lectin C-type domain Oxidored-like PF09791.9 CBY16370.1 - 0.097 12.4 3.3 0.17 11.6 3.3 1.5 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal LPG_synthase_TM PF03706.13 CBY16371.1 - 0.003 17.1 0.1 0.0033 17.0 0.1 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Ctr PF04145.15 CBY16371.1 - 0.028 15.1 0.1 0.033 14.8 0.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Amnionless PF14828.6 CBY16371.1 - 0.052 12.4 0.0 0.058 12.2 0.0 1.0 1 0 0 1 1 1 0 Amnionless TRAP-gamma PF07074.12 CBY16371.1 - 0.29 10.7 3.9 5.3 6.6 2.6 2.0 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) bZIP_Maf PF03131.17 CBY16373.1 - 8.9e-06 26.1 15.3 8.9e-06 26.1 15.3 2.2 2 1 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CBY16373.1 - 0.00015 21.8 14.4 0.00015 21.8 14.4 2.8 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY16373.1 - 0.00023 21.2 17.0 0.0011 19.0 15.1 2.6 2 0 0 2 2 2 1 bZIP transcription factor SIKE PF05769.11 CBY16373.1 - 0.06 13.3 11.0 0.1 12.5 0.3 2.8 2 1 1 3 3 3 0 SIKE family Coat_F PF07875.12 CBY16373.1 - 0.12 12.6 1.8 0.34 11.2 1.8 1.7 1 0 0 1 1 1 0 Coat F domain PRKG1_interact PF15898.5 CBY16373.1 - 1.2 10.1 13.0 0.12 13.3 5.3 2.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FapA PF03961.13 CBY16373.1 - 2.7 6.5 8.4 0.22 10.1 2.6 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Macoilin PF09726.9 CBY16373.1 - 6.1 5.3 11.1 7.8 4.9 11.1 1.4 1 1 0 1 1 1 0 Macoilin family Ank_2 PF12796.7 CBY16375.1 - 2.7e-09 37.5 0.0 1.5e-05 25.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY16375.1 - 7.6e-09 36.0 0.0 0.00035 21.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY16375.1 - 2.8e-08 33.9 0.1 0.0087 16.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CBY16375.1 - 1.1e-07 32.0 0.0 0.00041 20.6 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY16375.1 - 0.00014 22.0 0.1 0.97 10.2 0.0 4.3 4 2 0 4 4 4 1 Ankyrin repeat TcpF PF06340.11 CBY16375.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F GTP_EFTU_D3 PF03143.17 CBY16376.1 - 1.5e-41 141.2 0.0 2.8e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBY16376.1 - 3.2e-14 53.1 0.4 1e-13 51.5 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CBY16376.1 - 0.013 15.4 0.6 0.027 14.4 0.2 1.7 2 0 0 2 2 2 0 Elongation factor Tu domain 4 NIF3 PF01784.18 CBY16376.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) RMI2 PF16100.5 CBY16377.1 - 0.0079 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Rho_RNA_bind PF07497.12 CBY16377.1 - 0.012 15.4 0.2 0.026 14.4 0.2 1.5 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain MFS_1 PF07690.16 CBY16378.1 - 3.6e-06 26.1 10.4 5.6e-05 22.2 1.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NARP1 PF12569.8 CBY16379.1 - 0.0016 17.5 4.6 0.0017 17.4 4.6 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Rotamase_2 PF13145.6 CBY16379.1 - 0.0024 18.7 1.6 0.0029 18.4 1.6 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain SURF2 PF05477.11 CBY16379.1 - 0.0065 16.2 5.1 0.0071 16.1 5.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) AP3D1 PF06375.11 CBY16379.1 - 0.0087 16.3 9.1 0.011 15.9 9.1 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 CAAP1 PF15335.6 CBY16379.1 - 0.0091 16.5 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 DUF755 PF05501.11 CBY16379.1 - 0.015 15.6 11.9 0.019 15.2 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) HGTP_anticodon2 PF12745.7 CBY16379.1 - 0.022 14.3 2.3 0.03 13.8 2.3 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Peptidase_S49_N PF08496.10 CBY16379.1 - 0.027 14.5 2.4 0.035 14.2 2.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CSRNP_N PF16019.5 CBY16379.1 - 0.041 13.8 2.3 0.046 13.6 2.3 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4718 PF15842.5 CBY16379.1 - 0.063 13.1 1.3 0.086 12.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) PPL5 PF18168.1 CBY16379.1 - 0.077 12.3 3.6 0.087 12.1 3.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SspB PF04386.13 CBY16379.1 - 0.082 12.8 1.9 0.12 12.3 1.9 1.2 1 0 0 1 1 1 0 Stringent starvation protein B DUF2397 PF09660.10 CBY16379.1 - 0.19 10.6 2.5 0.24 10.3 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Afi1 PF07792.12 CBY16379.1 - 0.25 11.8 4.0 0.31 11.5 4.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking OAD_gamma PF04277.13 CBY16379.1 - 0.68 10.6 3.4 1.1 9.9 3.4 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RRP14 PF15459.6 CBY16379.1 - 1.7 9.3 14.0 3.6 8.3 12.5 2.0 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 STAG PF08514.11 CBY16379.1 - 1.8 8.5 5.1 3.1 7.7 5.1 1.3 1 0 0 1 1 1 0 STAG domain IRF PF00605.17 CBY16380.1 - 2e-34 118.0 0.0 3.5e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor DUF2744 PF10910.8 CBY16382.1 - 0.042 13.8 0.0 0.061 13.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2744) DUF4551 PF15087.6 CBY16382.1 - 0.49 9.2 6.8 0.53 9.0 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CECR6_TMEM121 PF14997.6 CBY16384.1 - 0.0043 16.9 1.2 0.62 9.9 0.3 2.2 2 0 0 2 2 2 2 CECR6/TMEM121 family CECR6_TMEM121 PF14997.6 CBY16385.1 - 4e-15 56.2 4.5 5.1e-15 55.8 4.5 1.1 1 0 0 1 1 1 1 CECR6/TMEM121 family GreA_GreB PF01272.19 CBY16387.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term TTC5_OB PF16669.5 CBY16388.1 - 8.7e-26 89.9 0.0 1.2e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_11 PF13414.6 CBY16388.1 - 0.00012 21.7 0.5 0.21 11.3 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 CBY16388.1 - 0.00015 21.9 1.4 1.1 9.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY16388.1 - 0.0031 17.2 1.7 0.82 9.6 0.7 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY16388.1 - 0.026 14.6 1.7 11 6.4 0.8 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCHC PF00098.23 CBY16389.1 - 4.1e-07 29.8 11.1 0.0015 18.5 2.6 2.4 2 0 0 2 2 2 2 Zinc knuckle CLZ PF16526.5 CBY16389.1 - 0.0025 18.1 0.1 0.0051 17.2 0.1 1.6 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sipho_Gp157 PF05565.11 CBY16389.1 - 0.0055 16.7 0.1 0.0078 16.2 0.1 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 PHD PF00628.29 CBY16389.1 - 0.058 13.3 5.6 0.16 11.9 5.6 1.8 1 0 0 1 1 1 0 PHD-finger zf-CCHC_4 PF14392.6 CBY16389.1 - 0.16 11.7 12.6 0.67 9.7 3.1 2.3 1 1 1 2 2 2 0 Zinc knuckle DUF2205 PF10224.9 CBY16389.1 - 0.5 10.4 2.9 0.69 9.9 0.1 2.3 2 1 1 3 3 3 0 Short coiled-coil protein PRKCSH-like PF12999.7 CBY16391.1 - 4e-39 134.2 7.1 4e-39 134.2 7.1 3.3 2 2 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CBY16391.1 - 8.4e-31 106.8 0.1 8.4e-31 106.8 0.1 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CBY16391.1 - 4.6e-05 24.3 2.2 0.00025 22.0 2.2 2.3 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Fzo_mitofusin PF04799.13 CBY16391.1 - 0.048 13.2 3.9 0.13 11.9 3.9 1.7 1 0 0 1 1 1 0 fzo-like conserved region Ldl_recept_a PF00057.18 CBY16391.1 - 0.069 13.4 15.8 0.36 11.1 4.3 3.0 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A DUF948 PF06103.11 CBY16391.1 - 0.68 10.2 6.4 1.1 9.5 0.8 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PRKG1_interact PF15898.5 CBY16391.1 - 9.9 7.1 21.4 0.97 10.4 7.6 3.1 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain EGF_2 PF07974.13 CBY16396.1 - 5.8e-15 55.4 87.3 2.9e-05 24.3 14.7 6.6 6 0 0 6 6 6 5 EGF-like domain DUF3333 PF11812.8 CBY16396.1 - 0.0035 17.5 0.1 0.0062 16.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3333) EGF PF00008.27 CBY16396.1 - 0.055 13.8 72.0 0.097 13.0 5.5 7.1 7 0 0 7 7 7 0 EGF-like domain DEAD PF00270.29 CBY16397.1 - 3.3e-15 56.3 0.0 8e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 CBY16397.1 - 2.2e-07 31.1 0.2 3.2e-07 30.6 0.2 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CBY16397.1 - 2.7e-07 30.9 0.0 1.4e-06 28.6 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY16397.1 - 4.4e-05 23.5 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 CBY16397.1 - 0.034 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein SHQ1 PF04925.15 CBY16399.1 - 1.3e-35 122.5 0.1 1.9e-35 122.0 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein AAA PF00004.29 CBY16400.1 - 4.3e-30 104.8 0.0 7.5e-30 104.1 0.0 1.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBY16400.1 - 0.00086 19.1 0.0 0.0047 16.7 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBY16400.1 - 0.0014 18.9 0.0 0.25 11.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBY16400.1 - 0.003 17.6 0.0 0.16 12.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CBY16400.1 - 0.037 14.1 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CBY16400.1 - 0.039 13.2 0.1 0.25 10.5 0.0 2.1 2 1 1 3 3 3 0 TIP49 P-loop domain AAA_18 PF13238.6 CBY16400.1 - 0.061 13.9 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBY16400.1 - 0.089 13.2 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain LEH PF07858.12 CBY16400.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Viral_helicase1 PF01443.18 CBY16400.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CBY16400.1 - 0.12 12.8 0.0 1.6 9.1 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 CBY16400.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Trypsin PF00089.26 CBY16401.1 - 3.5e-47 161.1 0.0 4.7e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY16401.1 - 1.3e-05 26.2 0.0 2.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY16401.1 - 0.2 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Imm25 PF15564.6 CBY16403.1 - 0.059 13.3 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 25 Pkinase PF00069.25 CBY16403.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Mito_carr PF00153.27 CBY16404.1 - 1.3e-29 102.0 0.1 1.6e-09 37.5 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CBY16404.1 - 0.066 12.4 0.1 0.39 9.8 0.1 2.3 1 1 0 1 1 1 0 Gammaproteobacterial serine protease bZIP_2 PF07716.15 CBY16405.1 - 2.1e-11 43.7 12.7 2.1e-11 43.7 12.7 2.1 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY16405.1 - 1.6e-05 24.9 8.7 2.6e-05 24.2 8.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 CBY16405.1 - 0.0068 16.1 6.2 0.0068 16.1 6.2 1.3 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 ZapB PF06005.12 CBY16405.1 - 0.049 14.1 2.1 0.049 14.1 2.1 2.0 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_Maf PF03131.17 CBY16405.1 - 0.28 11.7 10.2 0.07 13.7 7.0 1.5 1 1 1 2 2 2 0 bZIP Maf transcription factor CCDC71L PF15374.6 CBY16405.1 - 0.35 10.1 6.8 0.41 9.9 6.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L AAA_22 PF13401.6 CBY16406.1 - 1.1e-14 54.8 0.0 5e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY16406.1 - 8.7e-13 49.0 0.2 1.7e-10 41.5 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CBY16406.1 - 1.2e-12 48.4 0.0 3.2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CBY16406.1 - 4.1e-05 23.9 0.6 0.00024 21.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBY16406.1 - 4.9e-05 22.9 0.1 9.7e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 CBY16406.1 - 0.00023 20.9 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBY16406.1 - 0.00034 20.6 0.0 0.00087 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBY16406.1 - 0.0011 18.3 0.0 0.0029 16.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin DUF2075 PF09848.9 CBY16406.1 - 0.002 17.4 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 CBY16406.1 - 0.002 17.9 0.5 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 CBY16406.1 - 0.003 17.6 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA lid domain Rad17 PF03215.15 CBY16406.1 - 0.0031 17.5 0.1 0.0076 16.2 0.1 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain TIP49 PF06068.13 CBY16406.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Cdc6_C PF09079.11 CBY16406.1 - 0.013 15.5 0.0 0.043 13.8 0.1 1.9 2 0 0 2 2 1 0 CDC6, C terminal winged helix domain PIF1 PF05970.14 CBY16406.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Viral_helicase1 PF01443.18 CBY16406.1 - 0.015 15.1 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CBY16406.1 - 0.015 15.7 0.1 0.062 13.7 0.1 2.2 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 CBY16406.1 - 0.016 15.1 0.3 0.05 13.5 0.3 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Helicase_RecD PF05127.14 CBY16406.1 - 0.02 14.7 0.0 0.085 12.7 0.0 2.0 2 0 0 2 2 2 0 Helicase AAA_11 PF13086.6 CBY16406.1 - 0.022 14.6 0.1 0.057 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CBY16406.1 - 0.031 14.3 1.1 0.099 12.6 0.1 2.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_17 PF13207.6 CBY16406.1 - 0.035 14.5 0.3 0.21 12.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain GvpD PF07088.11 CBY16406.1 - 0.044 12.4 0.0 0.071 11.7 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein DUF815 PF05673.13 CBY16406.1 - 0.06 12.5 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AIG1 PF04548.16 CBY16406.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_5 PF07728.14 CBY16406.1 - 0.073 13.1 0.1 1 9.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 CBY16406.1 - 0.082 13.3 0.1 0.26 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA C-terminal domain DEAD PF00270.29 CBY16406.1 - 0.087 12.6 0.9 1.4 8.7 0.1 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase TatD_DNase PF01026.21 CBY16408.1 - 1.2e-24 87.1 0.0 1.4e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Acatn PF13000.7 CBY16411.1 - 1.8e-13 49.9 1.5 2e-13 49.7 0.9 1.3 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 ELO PF01151.18 CBY16412.1 - 2.6e-55 187.7 20.0 2.9e-55 187.5 20.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CENP-O PF09496.10 CBY16412.1 - 0.13 12.2 0.4 0.2 11.6 0.4 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component fn3 PF00041.21 CBY16413.1 - 7.6e-30 103.1 0.2 8.8e-16 58.0 0.0 3.1 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY16413.1 - 0.00013 22.4 0.1 0.3 11.7 0.0 3.1 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CBY16413.1 - 0.051 13.9 0.0 0.42 11.0 0.0 2.3 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Pkinase_Tyr PF07714.17 CBY16414.1 - 4.3e-56 190.1 0.2 5.3e-56 189.8 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY16414.1 - 3.1e-23 82.5 0.0 4.2e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CBY16414.1 - 0.006 15.6 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY16414.1 - 0.19 11.0 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Symplekin_C PF12295.8 CBY16416.1 - 2.6e-56 190.7 5.3 2.6e-56 190.7 5.3 2.8 2 1 0 3 3 3 1 Symplekin tight junction protein C terminal Chordopox_L2 PF05803.12 CBY16416.1 - 0.011 15.5 3.8 3.4 7.6 0.4 3.2 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Metallophos PF00149.28 CBY16417.1 - 2.1e-40 139.4 0.1 2.7e-40 139.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBY16417.1 - 0.00032 21.1 0.1 0.00089 19.7 0.1 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 CBY16417.1 - 0.057 13.6 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF1394 PF07159.12 CBY16419.1 - 3.4e-25 88.9 1.5 3.7e-16 59.3 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1394) GCP_C_terminal PF04130.13 CBY16419.1 - 0.00031 20.3 1.1 0.00038 20.0 1.1 1.3 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Ribosomal_L11 PF00298.19 CBY16421.1 - 1.3e-05 25.6 0.6 2.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Pox_H7 PF04787.12 CBY16421.1 - 0.37 11.3 3.4 0.77 10.3 3.4 1.4 1 1 1 2 2 2 0 Late protein H7 PID PF00640.23 CBY16422.1 - 4.1e-06 26.9 0.0 7.4e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Asp-B-Hydro_N PF05279.11 CBY16424.1 - 2.5 8.1 15.2 4 7.4 15.2 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SAPS PF04499.15 CBY16424.1 - 4.1 6.1 14.6 4.2 6.0 14.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LAP1C PF05609.12 CBY16424.1 - 5.1 6.1 22.8 5.7 5.9 22.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 CBY16424.1 - 9.1 4.7 27.7 12 4.3 27.7 1.3 1 0 0 1 1 1 0 Macoilin family LNS2 PF08235.13 CBY16426.1 - 3.8e-17 62.5 0.0 4.2e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) EMP24_GP25L PF01105.24 CBY16427.1 - 1.4e-06 28.4 0.3 1.5e-06 28.3 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5640 PF18692.1 CBY16427.1 - 0.055 13.5 0.2 0.065 13.3 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5640) Phospholip_A2_1 PF00068.19 CBY16429.1 - 3.5e-05 24.2 0.2 6.2e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Phospholipase A2 AAA_6 PF12774.7 CBY16431.1 - 2.6e-35 121.9 0.1 2.4e-27 95.8 0.0 2.2 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CBY16431.1 - 4.2e-10 39.8 0.0 1.5e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF853 PF05872.12 CBY16431.1 - 0.0049 15.5 0.1 0.0098 14.5 0.0 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_7 PF12775.7 CBY16431.1 - 0.023 14.2 0.0 0.055 13.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 CBY16431.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 CBY16431.1 - 0.28 10.1 1.7 0.19 10.6 0.1 1.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DLEU7 PF15760.5 CBY16432.1 - 0.05 13.1 0.1 0.15 11.6 0.1 1.7 1 1 0 1 1 1 0 Leukemia-associated protein 7 Sulfotransfer_4 PF17784.1 CBY16433.1 - 5.3e-14 52.6 0.0 6.1e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain LURAP PF14854.6 CBY16433.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Leucine rich adaptor protein GAF_2 PF13185.6 CBY16434.1 - 5.3e-06 26.8 0.0 6.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CBY16434.1 - 0.02 15.5 0.0 0.023 15.3 0.0 1.3 1 0 0 1 1 1 0 GAF domain RPN13_C PF16550.5 CBY16436.1 - 9.8e-31 106.2 0.4 1.9e-30 105.3 0.4 1.5 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 CBY16436.1 - 4.2e-29 100.9 0.1 8.1e-29 100.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ivy PF08816.11 CBY16438.1 - 0.68 10.1 6.3 3.3 7.9 0.6 2.5 1 1 1 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) AhpC-TSA PF00578.21 CBY16439.1 - 3e-39 133.8 0.0 4e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY16439.1 - 2.9e-18 66.0 0.0 3.8e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBY16439.1 - 1.9e-13 50.0 0.0 4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CBY16439.1 - 0.0093 15.9 0.2 0.024 14.6 0.0 1.7 2 0 0 2 2 2 1 SCO1/SenC LAP1C PF05609.12 CBY16440.1 - 0.011 14.8 0.3 0.014 14.5 0.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TMEM251 PF15190.6 CBY16440.1 - 0.041 13.8 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 251 UPF0181 PF03701.14 CBY16440.1 - 0.048 13.3 0.1 0.072 12.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Epiglycanin_C PF14654.6 CBY16440.1 - 0.21 11.6 1.9 0.42 10.7 1.9 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Corona_S2 PF01601.16 CBY16440.1 - 0.51 8.8 2.7 0.7 8.3 2.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TP53IP5 PF15331.6 CBY16440.1 - 1.7 8.7 4.1 1.1 9.4 2.5 1.4 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF1387 PF07139.11 CBY16440.1 - 2.5 7.8 10.4 3.1 7.5 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Sulfotransfer_4 PF17784.1 CBY16441.1 - 1.4e-42 146.0 0.0 1.7e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Headcase PF16002.5 CBY16441.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Headcase protein FAM176 PF14851.6 CBY16442.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.3 1 1 1 2 2 2 0 FAM176 family NOA36 PF06524.12 CBY16442.1 - 2.2 7.5 30.8 2.9 7.1 30.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 CBY16442.1 - 7.5 4.6 30.3 8.1 4.5 30.3 1.0 1 0 0 1 1 1 0 Nop14-like family CysG_dimeriser PF10414.9 CBY16443.1 - 0.0043 16.8 0.5 0.011 15.5 0.5 1.7 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region Ank_4 PF13637.6 CBY16444.1 - 1.5e-12 47.7 1.2 5.9e-07 29.9 0.2 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY16444.1 - 1.4e-09 38.4 0.1 3.5e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY16444.1 - 5.9e-07 29.6 0.1 1.9e-06 28.0 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY16444.1 - 9.2e-06 25.6 0.1 0.0014 18.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CBY16444.1 - 0.00017 21.9 0.0 0.0016 18.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat SAM_1 PF00536.30 CBY16444.1 - 0.0042 17.5 0.1 0.012 16.1 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PUF PF00806.19 CBY16444.1 - 0.13 12.0 0.2 34 4.4 0.1 3.0 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat DEAD PF00270.29 CBY16445.1 - 5.1e-28 98.0 0.5 1.4e-17 64.0 0.0 2.7 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY16445.1 - 4.5e-27 94.6 0.0 1.8e-26 92.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 CBY16445.1 - 2.3e-16 59.8 0.5 8.1e-16 58.1 0.2 2.2 2 0 0 2 2 2 1 GUCT (NUC152) domain ResIII PF04851.15 CBY16445.1 - 0.00027 21.0 1.5 0.00065 19.7 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY16445.1 - 0.00052 19.3 0.0 0.00052 19.3 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CBY16445.1 - 0.011 15.1 0.1 0.011 15.1 0.1 3.6 3 1 1 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Med19 PF10278.9 CBY16445.1 - 2.7 7.9 17.1 6.6 6.6 17.1 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MT PF12777.7 CBY16446.1 - 1e-11 44.5 1.1 2.3e-11 43.3 1.1 1.5 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CBY16447.1 - 1e-23 83.7 0.4 2e-23 82.7 0.4 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 CBY16447.1 - 1.1e-08 34.5 0.0 1.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor KLRAQ PF10205.9 CBY16447.1 - 0.04 14.1 0.3 0.061 13.6 0.3 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein VIT1 PF01988.19 CBY16449.1 - 0.0037 17.2 1.3 0.0037 17.2 1.3 1.0 1 0 0 1 1 1 1 VIT family DUF4131 PF13567.6 CBY16449.1 - 0.7 9.5 5.4 0.69 9.6 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Topoisom_I PF01028.20 CBY16450.1 - 5.4e-97 323.6 13.2 8.2e-97 323.0 13.2 1.3 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 CBY16450.1 - 1.5e-30 104.9 0.5 1.5e-30 104.9 0.5 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain DUF3090 PF11290.8 CBY16450.1 - 0.069 13.0 1.2 0.15 11.8 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Oleosin PF01277.17 CBY16450.1 - 0.21 11.4 0.8 0.4 10.4 0.6 1.5 1 1 0 1 1 1 0 Oleosin OmpH PF03938.14 CBY16450.1 - 0.31 11.4 21.3 0.14 12.5 12.1 2.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CBY16450.1 - 0.47 9.8 7.6 0.76 9.1 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Herpes_UL14 PF03580.14 CBY16450.1 - 0.9 9.8 9.2 0.23 11.7 3.4 2.7 2 1 1 3 3 3 0 Herpesvirus UL14-like protein Tetraspanin PF00335.20 CBY16452.1 - 1.1e-21 77.6 3.0 1.3e-21 77.4 3.0 1.0 1 0 0 1 1 1 1 Tetraspanin family COX15-CtaA PF02628.15 CBY16452.1 - 0.013 14.6 1.8 0.016 14.3 1.8 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein DUF5367 PF17329.2 CBY16452.1 - 0.018 15.2 1.5 0.018 15.2 1.5 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5367) EFTUD2 PF16004.5 CBY16453.1 - 0.038 14.6 2.9 0.07 13.7 2.9 1.4 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF2158 PF09926.9 CBY16453.1 - 0.15 11.9 0.2 0.37 10.6 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) SAPS PF04499.15 CBY16453.1 - 1.7 7.3 3.4 2.5 6.8 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein F-box-like PF12937.7 CBY16454.1 - 0.0016 18.3 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like Forkhead PF00250.18 CBY16458.1 - 2.2e-32 111.2 0.5 2.9e-32 110.8 0.5 1.1 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 CBY16458.1 - 0.06 13.7 0.0 0.084 13.2 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family Calici_PP_N PF08405.11 CBY16458.1 - 0.11 11.3 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 Viral polyprotein N-terminal Baculo_PEP_C PF04513.12 CBY16460.1 - 0.0061 16.6 0.1 0.0079 16.2 0.1 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 CBY16460.1 - 0.0062 16.4 0.6 0.007 16.3 0.6 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 CBY16460.1 - 0.022 14.9 3.0 0.037 14.1 3.0 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.11 CBY16460.1 - 0.023 14.9 2.3 0.049 13.9 2.3 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MreB_Mbl PF06723.13 CBY16460.1 - 0.036 12.9 0.5 0.042 12.7 0.5 1.1 1 0 0 1 1 1 0 MreB/Mbl protein DUF883 PF05957.13 CBY16460.1 - 0.043 14.4 0.2 0.065 13.9 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF2321 PF10083.9 CBY16460.1 - 0.064 12.9 0.3 0.075 12.7 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) GMP_PDE_delta PF05351.11 CBY16461.1 - 1.1e-33 116.5 0.1 1.7e-33 115.9 0.1 1.3 1 0 0 1 1 1 1 GMP-PDE, delta subunit PNP_UDP_1 PF01048.20 CBY16462.1 - 6.1e-05 22.4 0.2 6.5e-05 22.3 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily RSF PF14876.6 CBY16464.1 - 0.00095 18.2 0.1 0.0014 17.7 0.1 1.1 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator MAT1 PF06391.13 CBY16466.1 - 3.8e-29 102.0 20.4 6.4e-29 101.3 20.4 1.3 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CBY16466.1 - 4.1e-10 39.4 6.7 7.2e-10 38.6 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY16466.1 - 0.00018 21.4 6.2 0.00045 20.2 6.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Atg14 PF10186.9 CBY16466.1 - 0.0061 15.7 7.9 0.0071 15.5 7.9 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RING_5 PF14634.6 CBY16466.1 - 0.0085 16.0 8.4 0.023 14.7 8.4 1.7 1 1 1 2 2 2 1 zinc-RING finger domain Alpha_Helical PF18489.1 CBY16466.1 - 0.013 15.7 0.1 0.013 15.7 0.1 1.9 2 0 0 2 2 2 0 Alpha helical domain zf-C3HC4 PF00097.25 CBY16466.1 - 0.02 14.8 8.1 0.057 13.3 8.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY16466.1 - 0.12 12.7 5.7 0.23 11.8 5.7 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 CBY16466.1 - 0.17 11.8 9.5 0.68 9.8 9.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pyr_redox_2 PF07992.14 CBY16466.1 - 0.18 11.0 0.3 0.81 8.9 0.0 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase VP_N-CPKC PF11475.8 CBY16466.1 - 0.84 9.6 5.3 14 5.7 0.6 2.7 2 0 0 2 2 2 0 Virion protein N terminal domain zf-C3HC4_2 PF13923.6 CBY16466.1 - 1.7 8.5 8.7 8.5 6.3 8.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY16466.1 - 2.2 8.5 8.3 6.8 6.9 8.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING ATP-gua_Ptrans PF00217.19 CBY16467.1 - 6.1e-56 189.3 0.0 7.4e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain MSP1_C PF07462.11 CBY16468.1 - 1.7 7.2 4.1 1.8 7.1 4.1 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus S4 PF01479.25 CBY16469.1 - 2.2e-10 40.1 2.6 3.4e-10 39.5 2.6 1.3 1 0 0 1 1 1 1 S4 domain Folate_carrier PF01770.18 CBY16471.1 - 2 7.1 5.8 1.3 7.7 1.8 1.9 2 0 0 2 2 2 0 Reduced folate carrier Ig_3 PF13927.6 CBY17739.1 - 1.6e-13 51.1 4.8 3.4e-05 24.3 0.3 4.2 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CBY17739.1 - 2.7e-12 46.6 2.5 6.6e-07 29.3 0.1 4.3 3 1 0 3 3 3 3 Immunoglobulin I-set domain C2-set_2 PF08205.12 CBY17739.1 - 3.9e-12 46.1 3.1 1.9e-07 31.0 0.0 2.9 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 CBY17739.1 - 4.2e-12 46.1 10.1 1.8e-07 31.2 1.3 4.5 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CBY17739.1 - 1.2e-09 38.3 4.8 1.5e-06 28.4 0.4 4.0 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 CBY17739.1 - 1.1e-06 28.8 3.6 0.0008 19.6 0.2 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain SYF2 PF08231.12 CBY17739.1 - 0.0086 16.5 0.3 0.021 15.2 0.3 1.7 1 0 0 1 1 1 1 SYF2 splicing factor DUF1564 PF07600.11 CBY17739.1 - 0.072 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Ig_2 PF13895.6 CBY17740.1 - 7e-09 35.9 0.0 3.7e-05 24.0 0.0 3.1 1 1 2 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.6 CBY17740.1 - 2.1e-07 31.4 0.1 0.038 14.6 0.0 3.4 2 1 1 3 3 3 2 Immunoglobulin domain Insulin_TMD PF17870.1 CBY17740.1 - 4.6e-05 23.4 0.7 0.00012 22.0 0.7 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF4448 PF14610.6 CBY17740.1 - 0.014 15.1 0.2 0.033 14.0 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) I-set PF07679.16 CBY17740.1 - 0.045 13.8 0.0 5.9 7.0 0.0 3.3 2 1 1 3 3 3 0 Immunoglobulin I-set domain TMEM154 PF15102.6 CBY17740.1 - 0.081 12.8 0.2 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family DUF5385 PF17359.2 CBY17740.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) CAP PF00188.26 CBY17741.1 - 8.3e-17 62.2 0.4 7.6e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 Cysteine-rich secretory protein family TSP_1 PF00090.19 CBY17741.1 - 2.6e-07 30.8 10.3 2.6e-07 30.8 10.3 2.5 2 0 0 2 2 2 1 Thrombospondin type 1 domain Pox_A28 PF04584.14 CBY17741.1 - 0.29 11.3 2.4 3 8.0 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A28 family ADK PF00406.22 CBY17743.1 - 1.1e-40 139.1 0.0 1.5e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBY17743.1 - 1.1e-34 119.7 0.0 1.8e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY17743.1 - 2.2e-09 38.0 0.1 4.2e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBY17743.1 - 1.2e-06 28.8 0.0 5.5e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CBY17743.1 - 0.00022 21.0 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.19 CBY17743.1 - 0.00044 20.2 0.2 0.003 17.4 0.0 2.0 2 0 0 2 2 2 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 CBY17743.1 - 0.00067 19.0 0.1 0.0031 16.8 0.1 2.1 1 1 0 1 1 1 1 Zeta toxin Ploopntkinase1 PF18748.1 CBY17743.1 - 0.015 14.8 0.0 0.059 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 TetR_C_24 PF17932.1 CBY17743.1 - 0.064 13.5 0.3 12 6.2 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glycos_trans_3N PF02885.17 CBY17743.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain zf-C3HC4_2 PF13923.6 CBY17744.1 - 2.9e-08 33.4 8.6 7.2e-08 32.2 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY17744.1 - 3e-07 30.7 7.5 8.2e-07 29.3 7.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBY17744.1 - 5.1e-06 26.7 5.9 1.1e-05 25.6 5.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY17744.1 - 0.00014 21.9 4.2 0.00027 20.9 4.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CBY17744.1 - 0.00098 19.0 7.8 0.0019 18.1 7.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY17744.1 - 0.0023 17.7 6.8 0.005 16.7 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY17744.1 - 0.0028 17.5 4.5 0.0052 16.6 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 CBY17744.1 - 0.0038 17.2 10.4 0.0071 16.4 10.4 1.5 1 0 0 1 1 1 1 Zinc-finger Nucleoporin_FG PF13634.6 CBY17744.1 - 0.014 16.2 4.8 0.1 13.5 2.7 2.4 1 1 1 2 2 2 0 Nucleoporin FG repeat region zf-Nse PF11789.8 CBY17744.1 - 0.061 13.2 3.0 0.19 11.6 3.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit WSK PF03832.13 CBY17744.1 - 0.09 12.5 0.1 0.29 10.9 0.1 1.9 1 0 0 1 1 1 0 WSK motif zf-RING_UBOX PF13445.6 CBY17744.1 - 0.15 12.1 8.6 0.19 11.8 4.4 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 CBY17744.1 - 0.33 11.3 7.3 0.75 10.2 7.3 1.6 1 0 0 1 1 1 0 RING-like domain FYVE_2 PF02318.16 CBY17744.1 - 0.63 10.3 7.9 0.15 12.3 4.3 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger Peptidase_A22B PF04258.13 CBY17745.1 - 0.00039 20.0 0.1 0.00055 19.6 0.1 1.2 1 0 0 1 1 1 1 Signal peptide peptidase DUF515 PF04415.12 CBY17746.1 - 2.1 6.7 3.7 2.6 6.3 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RT_RNaseH_2 PF17919.1 CBY17748.1 - 2.1e-26 91.9 0.0 3.6e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY17748.1 - 2.2e-25 89.0 0.0 4e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY17748.1 - 2.9e-15 56.4 0.3 6.8e-15 55.2 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 CBY17748.1 - 0.0017 18.2 0.0 0.37 10.7 0.0 3.3 3 0 0 3 3 3 1 Reverse transcriptase thumb domain Baculo_LEF5 PF04838.12 CBY17748.1 - 0.076 13.1 0.2 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 RVT_1 PF00078.27 CBY17749.1 - 1e-15 57.9 0.3 3e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 CBY17749.1 - 0.045 14.1 0.1 0.21 11.9 0.1 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease CCDC53 PF10152.9 CBY17749.1 - 7 7.1 9.1 0.55 10.6 3.9 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Pkinase PF00069.25 CBY17750.1 - 1.3e-12 47.7 0.0 2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY17750.1 - 2.7e-09 36.7 0.0 3.8e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY17750.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family NPIP PF06409.11 CBY17752.1 - 0.09 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Cofilin_ADF PF00241.20 CBY17753.1 - 6.7e-14 51.7 0.0 7.6e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3234 PF11572.8 CBY17754.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) Forkhead PF00250.18 CBY17756.1 - 3.9e-31 107.2 0.1 5.7e-31 106.6 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain Trypsin PF00089.26 CBY17757.1 - 3.2e-43 148.1 1.3 4.9e-43 147.5 1.3 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY17757.1 - 0.00015 22.7 0.0 0.00033 21.6 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY17757.1 - 0.0023 18.3 0.4 0.0044 17.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) P4Ha_N PF08336.11 CBY17758.1 - 3.3e-20 72.5 0.2 5.6e-20 71.7 0.2 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CBY17758.1 - 8.8e-13 49.0 0.0 1.9e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CBY17758.1 - 0.00026 21.4 0.0 0.00055 20.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Not3 PF04065.15 CBY17758.1 - 0.041 13.3 4.6 0.072 12.5 4.6 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Asp5 PF17000.5 CBY17758.1 - 0.087 13.0 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 Ion_trans PF00520.31 CBY17759.1 - 0.015 14.5 4.9 0.022 14.0 4.9 1.2 1 0 0 1 1 1 0 Ion transport protein CDK2AP PF09806.9 CBY17759.1 - 0.029 14.4 2.7 0.048 13.7 2.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3413 PF11893.8 CBY17759.1 - 0.074 12.2 6.7 0.06 12.5 4.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) LicD PF04991.13 CBY17759.1 - 0.59 10.2 7.0 0.83 9.8 7.0 1.2 1 0 0 1 1 1 0 LicD family Lung_7-TM_R PF06814.13 CBY17759.1 - 0.82 8.9 7.0 2.7 7.2 7.0 1.6 1 1 0 1 1 1 0 Lung seven transmembrane receptor p450 PF00067.22 CBY17759.1 - 1.6 7.4 7.5 3.9 6.1 0.6 2.0 1 1 1 2 2 2 0 Cytochrome P450 Ninjurin PF04923.12 CBY17759.1 - 2.8 7.9 8.5 0.64 10.0 3.8 2.2 1 1 0 2 2 2 0 Ninjurin VASt PF16016.5 CBY17760.1 - 9.2e-19 68.4 0.2 1.3e-18 67.9 0.2 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF3641 PF12345.8 CBY17760.1 - 0.063 13.3 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3641) DUF5402 PF17393.2 CBY17761.1 - 0.06 13.3 0.2 0.096 12.6 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5402) zf-RING_5 PF14634.6 CBY17762.1 - 4e-08 33.1 11.4 6.1e-08 32.5 11.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY17762.1 - 4.6e-08 32.8 8.8 6.9e-08 32.2 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY17762.1 - 2.6e-07 30.8 10.6 4e-07 30.3 10.6 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBY17762.1 - 1.1e-06 28.4 9.4 2.7e-06 27.1 9.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY17762.1 - 4.8e-06 26.3 10.5 9.2e-06 25.4 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY17762.1 - 1.4e-05 25.0 3.3 3.5e-05 23.8 3.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 CBY17762.1 - 0.00031 20.4 9.6 0.00056 19.7 9.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CBY17762.1 - 0.00067 19.4 11.7 0.0018 18.0 11.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vpu PF00558.19 CBY17762.1 - 0.0091 15.7 1.1 0.13 12.0 0.5 2.4 2 1 0 2 2 2 1 Vpu protein TrbM PF07424.11 CBY17762.1 - 0.014 15.4 2.2 0.018 15.0 2.2 1.2 1 0 0 1 1 1 0 TrbM zf-RING_6 PF14835.6 CBY17762.1 - 0.021 14.7 1.8 0.039 13.8 1.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1494 PF07379.11 CBY17762.1 - 0.033 14.0 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) NEXCaM_BD PF16644.5 CBY17762.1 - 0.044 14.0 0.6 0.06 13.6 0.6 1.3 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin zf-UDP PF14569.6 CBY17762.1 - 0.066 13.3 5.7 0.13 12.4 5.7 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF1272 PF06906.11 CBY17762.1 - 0.091 12.9 8.6 0.14 12.3 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 CBY17762.1 - 0.13 12.6 9.7 0.33 11.3 9.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain Rtf2 PF04641.12 CBY17762.1 - 0.62 9.4 11.7 0.62 9.4 10.3 1.7 1 1 1 2 2 2 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 CBY17762.1 - 0.63 10.2 14.2 8.4 6.6 14.4 2.5 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING FPP PF05911.11 CBY17763.1 - 0.0082 14.4 49.4 0.0078 14.5 25.5 2.2 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil DUF3584 PF12128.8 CBY17763.1 - 0.018 12.6 46.8 0.018 12.6 45.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) N6_N4_Mtase PF01555.18 CBY17763.1 - 0.099 12.3 3.6 0.5 10.0 3.6 2.1 1 1 0 1 1 1 0 DNA methylase FUSC PF04632.12 CBY17763.1 - 1.2 7.5 13.6 0.28 9.7 1.9 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 CBY17763.1 - 1.2 9.4 36.0 0.16 12.3 4.5 5.4 3 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 CBY17763.1 - 2.1 8.4 57.5 0.059 13.5 19.8 3.5 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Sec20 PF03908.13 CBY17763.1 - 7.2 6.6 12.6 6.2 6.8 2.2 3.3 2 2 0 2 2 2 0 Sec20 CUB PF00431.20 CBY17764.1 - 1.2e-24 86.7 0.1 1.7e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 CUB domain RAP1 PF07218.11 CBY17764.1 - 0.25 9.6 17.7 0.32 9.2 17.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Secretin_N_2 PF07655.13 CBY17764.1 - 0.4 11.3 15.5 0.75 10.4 15.5 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain SPX PF03105.19 CBY17764.1 - 1.1 9.1 8.1 1.4 8.7 8.1 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CBY17764.1 - 1.5 7.6 7.8 2 7.2 7.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2076 PF09849.9 CBY17764.1 - 2.6 8.0 6.6 3.7 7.5 6.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) BUD22 PF09073.10 CBY17764.1 - 7.1 5.9 12.9 8.9 5.5 12.9 1.0 1 0 0 1 1 1 0 BUD22 Kelch_4 PF13418.6 CBY17765.1 - 0.029 14.4 0.1 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain PCYCGC PF13798.6 CBY17766.1 - 0.082 12.8 2.1 0.11 12.4 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif SQS_PSY PF00494.19 CBY17766.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Squalene/phytoene synthase Radical_SAM PF04055.21 CBY17766.1 - 2.4 8.5 5.8 5.5 7.3 5.8 1.8 1 1 0 1 1 1 0 Radical SAM superfamily Tctex-1 PF03645.13 CBY17770.1 - 1.8e-11 44.2 0.1 2.7e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M14 PF00246.24 CBY17771.1 - 1.6e-50 172.5 0.0 2.1e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2990 PF11693.8 CBY17771.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) Peptidase_M14 PF00246.24 CBY17772.1 - 4.1e-09 36.7 0.1 6e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Jnk-SapK_ap_N PF09744.9 CBY17774.1 - 2.1e-33 115.8 13.6 2.1e-33 115.8 13.6 4.1 2 1 0 3 3 3 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 CBY17774.1 - 3.1e-17 62.5 6.4 3.1e-17 62.5 6.4 4.3 4 1 1 5 5 5 1 JNK-interacting protein leucine zipper II Reg_prop PF07494.11 CBY17774.1 - 0.09 13.0 0.1 16 6.1 0.0 3.4 2 0 0 2 2 2 0 Two component regulator propeller DUF773 PF05600.12 CBY17775.1 - 1.5e-38 132.8 3.9 1.9e-38 132.5 3.9 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DUF3388 PF11868.8 CBY17775.1 - 0.17 11.2 1.0 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) DUF2096 PF09869.9 CBY17775.1 - 9.2 6.3 9.3 2.1 8.4 0.1 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) Mucin PF01456.17 CBY17778.1 - 0.0094 15.9 31.0 0.016 15.2 31.0 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Med3 PF11593.8 CBY17778.1 - 0.4 9.8 21.4 0.57 9.3 21.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ndc1_Nup PF09531.10 CBY17778.1 - 1.4 7.5 4.2 1.8 7.2 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SSP160 PF06933.11 CBY17778.1 - 7.3 4.7 19.0 10 4.2 19.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PP_M1 PF03012.14 CBY17778.1 - 8.4 5.8 5.7 8.2 5.9 4.6 1.5 1 1 0 1 1 1 0 Phosphoprotein DUF1304 PF06993.12 CBY17779.1 - 1.2e-40 137.9 6.7 1.4e-40 137.7 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) PNP_phzG_C PF10590.9 CBY17780.1 - 2e-20 72.6 1.3 4.3e-20 71.5 1.3 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CBY17780.1 - 6.5e-18 64.7 0.0 9.5e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 CBY17780.1 - 0.0026 18.4 0.0 0.0043 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 CBY17780.1 - 0.032 13.8 0.1 0.092 12.3 0.1 1.9 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like LpxK PF02606.14 CBY17781.1 - 6.8e-64 216.0 0.0 7.8e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Sulfatase PF00884.23 CBY17782.1 - 3.2e-16 59.6 0.0 4.5e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY17782.1 - 0.00085 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SWC7 PF17330.2 CBY17782.1 - 0.027 14.5 0.5 0.31 11.1 0.5 2.3 1 1 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 DUF1501 PF07394.12 CBY17782.1 - 0.15 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Kelch_2 PF07646.15 CBY17783.1 - 0.00043 20.1 0.9 1.8 8.7 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY17783.1 - 0.00053 20.2 0.2 5.5 7.4 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CBY17783.1 - 0.0017 18.3 5.4 0.0019 18.1 0.0 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 CBY17783.1 - 0.13 11.9 0.1 9 6.0 0.0 3.2 3 0 0 3 3 3 0 Kelch motif HEAT PF02985.22 CBY17784.1 - 0.001 19.1 0.3 0.034 14.4 0.0 2.8 3 0 0 3 3 3 1 HEAT repeat RRM_1 PF00076.22 CBY17785.1 - 2e-24 85.2 0.0 6.8e-14 51.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY17785.1 - 5.5e-09 36.0 0.9 0.00075 19.5 0.2 2.6 2 1 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 CBY17785.1 - 2.3e-05 24.4 1.5 0.0085 16.1 0.1 2.5 2 0 0 2 2 2 2 Limkain b1 DbpA PF03880.15 CBY17785.1 - 0.00028 20.8 0.1 0.01 15.8 0.0 2.6 3 0 0 3 3 3 1 DbpA RNA binding domain RRM_occluded PF16842.5 CBY17785.1 - 0.0042 16.9 0.0 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBY17785.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 CBY17785.1 - 0.044 13.6 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) BNR_4 PF15892.5 CBY17785.1 - 0.045 13.1 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-containing family member SET_assoc PF11767.8 CBY17785.1 - 0.094 12.4 0.2 2.3 7.9 0.1 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_5 PF13893.6 CBY17785.1 - 0.21 11.2 0.0 0.58 9.8 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chromo PF00385.24 CBY17786.1 - 0.04 13.8 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain OB_Dis3 PF17849.1 CBY17786.1 - 0.058 13.4 0.1 0.096 12.7 0.1 1.4 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) zf-RING_2 PF13639.6 CBY17788.1 - 9.1e-07 29.1 16.1 1.4e-06 28.5 16.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY17788.1 - 3.5e-06 26.8 14.5 6.3e-06 25.9 14.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY17788.1 - 6.4e-05 22.7 15.5 0.00014 21.6 15.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY17788.1 - 7.6e-05 22.6 16.7 0.00012 22.0 16.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY17788.1 - 0.00028 20.7 12.9 0.0055 16.5 12.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY17788.1 - 0.00065 19.5 17.2 0.0014 18.4 17.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY17788.1 - 0.0031 17.5 13.5 0.0062 16.5 8.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 CBY17788.1 - 0.011 15.5 15.0 0.02 14.7 15.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2256 PF10013.9 CBY17788.1 - 0.016 15.3 0.7 0.016 15.3 0.7 3.1 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_11 PF17123.5 CBY17788.1 - 0.024 14.4 11.9 0.034 13.9 7.1 2.5 1 1 2 3 3 3 0 RING-like zinc finger Baculo_IE-1 PF05290.11 CBY17788.1 - 0.13 12.2 11.5 0.19 11.6 11.5 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) UBZ_FAAP20 PF15750.5 CBY17788.1 - 0.19 11.7 6.5 1.2 9.1 3.8 2.6 2 1 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-C3HC4_4 PF15227.6 CBY17788.1 - 0.53 10.5 13.7 25 5.1 14.6 2.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PolC_DP2 PF03833.13 CBY17788.1 - 1.2 6.9 5.3 1.3 6.8 5.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Rtf2 PF04641.12 CBY17788.1 - 2 7.7 9.3 4.9 6.4 9.3 1.6 1 1 0 1 1 1 0 Rtf2 RING-finger Prok-RING_1 PF14446.6 CBY17788.1 - 5 7.1 16.0 0.81 9.7 0.4 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 CBY17788.1 - 9.5 6.6 16.9 2.5e+02 2.1 16.9 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain Ofd1_CTDD PF10637.9 CBY17789.1 - 0.055 12.8 1.2 0.069 12.5 1.2 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term RNA_pol_Rpb1_7 PF04990.12 CBY17789.1 - 1.4 8.9 6.5 2.4 8.1 6.2 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 7 DUF5339 PF17274.2 CBY17790.1 - 0.086 13.7 5.6 1.4 9.9 0.2 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5339) Methyltrn_RNA_3 PF02598.17 CBY17791.1 - 1.9e-104 349.2 0.0 2.6e-104 348.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 CBY17791.1 - 0.016 15.4 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 SpoU rRNA Methylase family Exonuc_VII_L PF02601.15 CBY17791.1 - 0.11 12.1 5.5 0.15 11.6 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4180 PF13788.6 CBY17791.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) Fmp27_WPPW PF10359.9 CBY17791.1 - 4.7 6.0 9.6 6.5 5.5 9.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMPIT PF07851.13 CBY17791.1 - 8.2 5.6 10.1 11 5.1 10.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 CBY17791.1 - 8.8 4.1 7.4 12 3.7 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RPA_C PF08784.11 CBY17792.1 - 3.9e-06 27.5 0.1 3.9e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Replication protein A C terminal EF-hand_1 PF00036.32 CBY17793.1 - 6.2e-39 128.7 13.6 7.5e-09 34.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY17793.1 - 3.5e-33 113.9 7.1 3.9e-16 59.2 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY17793.1 - 2e-31 105.2 8.8 1.1e-08 34.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBY17793.1 - 1.1e-27 94.2 19.4 6.5e-09 34.9 0.1 4.4 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CBY17793.1 - 7.8e-27 92.9 11.2 9.6e-11 41.4 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CBY17793.1 - 7.8e-19 67.8 0.4 4.2e-09 36.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBY17793.1 - 4.2e-13 49.2 4.4 9e-07 28.8 0.5 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY17793.1 - 1.8e-07 31.4 0.7 0.00015 22.0 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBY17793.1 - 1.1e-05 26.2 0.0 0.00046 21.0 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CBY17793.1 - 5.6e-05 23.3 1.8 0.1 12.8 0.1 3.2 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 CBY17793.1 - 6.1e-05 21.8 0.0 7.4e-05 21.5 0.0 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF5580) VCBS PF13517.6 CBY17793.1 - 0.00014 22.4 0.0 0.053 14.1 0.0 2.3 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SurA_N_2 PF13623.6 CBY17793.1 - 0.0021 18.0 1.0 0.0032 17.3 0.9 1.3 1 1 0 1 1 1 1 SurA N-terminal domain EF-hand_14 PF17959.1 CBY17793.1 - 0.0023 18.3 0.6 0.45 10.9 0.1 2.5 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 CBY17793.1 - 0.0048 16.9 1.0 0.41 10.6 0.1 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB UPF0154 PF03672.13 CBY17793.1 - 0.0082 16.2 0.0 1.5 8.9 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Phage_CP76 PF06892.11 CBY17793.1 - 0.01 15.3 0.2 0.015 14.9 0.2 1.1 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) DUF2666 PF10869.8 CBY17793.1 - 0.024 14.9 0.3 4.3 7.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) VbhA PF18495.1 CBY17793.1 - 0.038 13.9 2.0 22 5.0 0.1 3.6 4 0 0 4 4 3 0 Antitoxin VbhA Caleosin PF05042.13 CBY17793.1 - 0.053 13.5 0.9 5.7 6.8 0.0 3.1 2 2 1 3 3 3 0 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CBY17793.1 - 0.055 13.8 2.0 0.8 10.0 0.2 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 Adenine_glyco PF03352.13 CBY17793.1 - 0.073 12.8 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyladenine glycosylase PDZ_1 PF12812.7 CBY17793.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 PDZ-like domain PMBR PF09373.10 CBY17793.1 - 0.11 12.7 0.1 1.2e+02 3.1 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat TcdB_toxin_midN PF12256.8 CBY17793.1 - 0.19 11.0 0.8 1.1 8.6 0.0 2.4 1 1 2 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region NIR_SIR_ferr PF03460.17 CBY17793.1 - 0.22 11.4 0.9 13 5.7 0.0 3.2 3 1 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain UBA_6 PF18039.1 CBY17793.1 - 0.33 10.9 1.9 24 5.0 0.2 2.6 2 1 0 2 2 2 0 UBA-like domain EF-hand_10 PF14788.6 CBY17793.1 - 0.4 10.6 3.8 3 7.8 0.2 3.1 3 0 0 3 3 3 0 EF hand DUF533 PF04391.12 CBY17793.1 - 4.9 6.7 7.8 17 4.9 5.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF533) CHGN PF05679.16 CBY17795.1 - 1.2e-22 80.5 0.8 1.6e-22 80.1 0.8 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY17795.1 - 4.8e-17 62.2 0.1 4.8e-17 62.2 0.1 2.0 2 1 0 2 2 2 1 Fringe-like DUF4618 PF15397.6 CBY17795.1 - 0.0081 15.6 0.3 0.016 14.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Galactosyl_T PF01762.21 CBY17795.1 - 0.011 15.6 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Galactosyltransferase Glycos_transf_2 PF00535.26 CBY17795.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 ORC2 PF04084.14 CBY17798.1 - 0.009 15.0 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 PhoQ_Sensor PF08918.10 CBY17798.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoQ Sensor MIG-14_Wnt-bd PF06664.12 CBY17800.1 - 9e-35 120.3 10.7 1e-34 120.1 10.7 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion PgpA PF04608.13 CBY17800.1 - 0.058 13.4 4.5 0.1 12.6 3.9 1.8 1 1 0 1 1 1 0 Phosphatidylglycerophosphatase A PDR_CDR PF06422.12 CBY17800.1 - 0.52 10.2 4.6 13 5.8 2.6 2.9 2 1 0 2 2 2 0 CDR ABC transporter Phospholamban PF04272.14 CBY17800.1 - 0.81 9.2 5.4 0.26 10.8 0.3 2.3 2 0 0 2 2 2 0 Phospholamban bZIP_1 PF00170.21 CBY17801.1 - 4.2e-10 39.6 16.8 5.2e-10 39.3 16.8 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY17801.1 - 5e-06 26.5 19.4 7.4e-06 26.0 19.4 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY17801.1 - 7.9e-06 26.3 9.8 1e-05 26.0 9.8 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor FlaC_arch PF05377.11 CBY17801.1 - 0.0089 16.4 0.4 0.014 15.8 0.4 1.2 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Zein-binding PF04576.15 CBY17801.1 - 0.011 16.0 5.3 0.015 15.6 5.3 1.1 1 0 0 1 1 1 0 Zein-binding TSC22 PF01166.18 CBY17801.1 - 0.039 14.3 1.5 0.073 13.4 1.5 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family NPV_P10 PF05531.12 CBY17801.1 - 0.096 13.2 0.1 0.14 12.6 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Pox_G5 PF04599.12 CBY17801.1 - 2 7.3 9.3 2.4 7.1 9.3 1.0 1 0 0 1 1 1 0 Poxvirus G5 protein ZapB PF06005.12 CBY17801.1 - 3.2 8.3 10.7 0.27 11.7 4.1 2.0 1 1 1 2 2 2 0 Cell division protein ZapB Homeodomain PF00046.29 CBY17802.1 - 4.2e-20 71.4 0.4 5.5e-20 71.0 0.4 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY17802.1 - 1.7e-16 59.8 0.0 2.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 CBY17802.1 - 0.00047 20.0 0.0 0.00075 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 CBY17802.1 - 0.0036 17.3 0.1 0.0082 16.2 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix CENP-B_N PF04218.13 CBY17802.1 - 0.023 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_26 PF13443.6 CBY17802.1 - 0.045 14.2 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 CBY17802.1 - 0.051 13.4 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Homez PF11569.8 CBY17802.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Acetyltransf_1 PF00583.25 CBY17803.1 - 0.00014 22.1 0.0 0.00017 21.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 CBY17803.1 - 0.00041 20.0 0.0 0.00047 19.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY17803.1 - 0.015 15.8 0.0 0.018 15.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY17803.1 - 0.016 15.2 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 FR47-like protein PEP_mutase PF13714.6 CBY17804.1 - 0.05 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase zf-ZPR1 PF03367.13 CBY17804.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Oxysterol_BP PF01237.18 CBY17805.1 - 4.5e-134 447.0 1.8 5.2e-134 446.8 1.8 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein POTRA_3 PF17287.2 CBY17805.1 - 0.35 10.3 1.0 0.61 9.6 0.0 1.8 2 0 0 2 2 2 0 POTRA domain TTL PF03133.15 CBY17806.1 - 4e-87 292.1 0.0 4e-87 292.1 0.0 2.0 2 1 1 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY17806.1 - 2e-06 27.2 0.0 0.0025 17.1 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY17806.1 - 0.0099 15.2 0.0 0.32 10.2 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp AMP-binding PF00501.28 CBY17807.1 - 1.4e-06 27.2 0.0 1.4e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme OrfB_Zn_ribbon PF07282.11 CBY17807.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Herpes_TAF50 PF03326.13 CBY17808.1 - 0.61 8.7 3.1 0.86 8.2 3.1 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) P_C PF06640.11 CBY17808.1 - 4.3 7.4 6.4 5.8 7.0 6.4 1.2 1 0 0 1 1 1 0 P protein C-terminus KBP_C PF12309.8 CBY17809.1 - 1.4e-26 93.9 0.0 1.5e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 KIF-1 binding protein C terminal KBP_C PF12309.8 CBY17810.1 - 2e-28 100.0 0.0 2.3e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 KIF-1 binding protein C terminal DNA_pol_B_palm PF14792.6 CBY17810.1 - 0.083 13.1 0.1 0.1 12.8 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase beta palm PKD_channel PF08016.12 CBY17812.1 - 7.4e-10 38.1 14.9 1e-09 37.6 14.9 1.1 1 0 0 1 1 1 1 Polycystin cation channel PH PF00169.29 CBY17813.1 - 0.052 14.1 0.0 0.062 13.8 0.0 1.2 1 0 0 1 1 1 0 PH domain Kelch_6 PF13964.6 CBY17818.1 - 0.13 12.6 3.0 16 6.0 0.6 3.2 2 2 1 3 3 3 0 Kelch motif Kelch_1 PF01344.25 CBY17818.1 - 2 8.1 5.3 0.72 9.5 0.5 2.7 4 0 0 4 4 4 0 Kelch motif CDC37_M PF08565.11 CBY17819.1 - 2.7e-20 72.5 1.0 7.3e-20 71.1 1.0 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 CBY17819.1 - 2.4e-12 47.9 17.9 6.3e-12 46.5 17.8 1.9 1 1 0 1 1 1 1 Cdc37 N terminal kinase binding CPSase_L_D3 PF02787.19 CBY17819.1 - 0.003 17.9 3.8 0.003 17.9 3.8 1.6 1 1 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Ribonuc_red_2_N PF08471.10 CBY17819.1 - 0.0088 16.2 0.7 0.0088 16.2 0.7 2.3 1 1 1 2 2 2 1 Class II vitamin B12-dependent ribonucleotide reductase Baculo_VP39 PF04501.12 CBY17820.1 - 0.011 15.3 0.1 0.011 15.3 0.1 1.0 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 CH PF00307.31 CBY17821.1 - 1.9e-22 79.5 0.0 2.8e-17 62.9 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain Methyltransf_12 PF08242.12 CBY17821.1 - 0.061 14.1 0.3 0.44 11.3 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Ly49 PF08391.10 CBY17821.1 - 8.8 6.7 6.0 2.2 8.7 0.5 2.5 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region Trypsin PF00089.26 CBY17822.1 - 4.3e-13 49.6 0.1 5e-13 49.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin Glyco_hydro_35 PF01301.19 CBY17823.1 - 8e-31 107.8 2.2 1.3e-30 107.2 0.1 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 CBY17823.1 - 0.054 14.1 0.2 0.14 12.8 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain RhoGAP PF00620.27 CBY17825.1 - 1.5e-28 99.5 0.0 2.2e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 CBY17825.1 - 1.6e-05 24.7 7.7 2.8e-05 23.9 7.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CBY17825.1 - 2.7 8.2 8.4 40 4.4 8.4 2.5 1 1 0 1 1 1 0 PHD-finger MFS_1 PF07690.16 CBY17828.1 - 3.4e-16 59.1 2.9 4e-16 58.9 2.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY17828.1 - 0.00027 19.9 0.2 0.00027 19.9 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Gly-zipper_Omp PF13488.6 CBY17830.1 - 6.4e-06 26.1 9.9 9.1e-06 25.6 9.9 1.2 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 CBY17830.1 - 0.0004 20.1 11.7 0.00055 19.6 11.7 1.2 1 0 0 1 1 1 1 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 CBY17830.1 - 0.0015 18.6 10.0 0.0025 17.9 10.0 1.3 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide DUF1269 PF06897.12 CBY17830.1 - 0.0061 16.8 1.5 0.0099 16.1 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 CBY17830.1 - 0.059 13.3 15.3 0.099 12.5 15.3 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 CBY17830.1 - 0.21 11.4 19.2 0.3 10.9 19.2 1.1 1 0 0 1 1 1 0 Glycine-zipper domain DUF4551 PF15087.6 CBY17830.1 - 0.54 9.0 4.0 0.52 9.1 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.7 CBY17830.1 - 1.2 7.2 4.6 1.2 7.2 4.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 CBY17830.1 - 8 5.6 13.4 9.1 5.4 12.9 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Peptidase_M1 PF01433.20 CBY17831.1 - 2.1e-52 177.9 0.1 2.9e-52 177.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain WLM PF08325.10 CBY17831.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 WLM domain PEHE PF15275.6 CBY17833.1 - 2.1e-08 34.8 4.0 2.1e-08 34.8 4.0 2.8 2 2 0 2 2 2 1 PEHE domain TSC22 PF01166.18 CBY17833.1 - 0.027 14.8 0.7 0.027 14.8 0.7 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family FtsX_ECD PF18075.1 CBY17833.1 - 0.066 13.8 1.4 0.066 13.8 1.4 3.4 3 1 0 4 4 4 0 FtsX extracellular domain Paramyxo_ncap PF00973.19 CBY17833.1 - 3.3 6.5 7.3 0.075 11.9 0.5 1.6 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein PKcGMP_CC PF16808.5 CBY17833.1 - 5.9 6.8 18.1 0.11 12.4 5.4 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sulfotransfer_1 PF00685.27 CBY17834.1 - 1.5e-08 34.5 0.0 1.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain FliL PF03748.14 CBY17835.1 - 0.012 16.1 2.1 0.022 15.3 0.4 2.2 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL Clathrin PF00637.20 CBY17835.1 - 0.024 14.5 1.8 0.055 13.3 1.8 1.8 1 1 0 1 1 1 0 Region in Clathrin and VPS HHH_9 PF17674.1 CBY17835.1 - 0.032 15.1 1.7 4.2 8.4 0.2 2.3 2 0 0 2 2 2 0 HHH domain AAA_6 PF12774.7 CBY17838.1 - 1.8e-156 520.2 0.0 1.6e-155 517.1 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBY17838.1 - 3.9e-139 464.2 6.7 3.9e-139 464.2 6.7 5.2 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBY17838.1 - 2.9e-118 394.6 0.2 5.2e-117 390.5 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBY17838.1 - 2.4e-104 348.3 0.0 4.8e-103 344.0 0.0 2.9 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBY17838.1 - 1.1e-94 315.7 1.6 1.1e-94 315.7 1.6 3.4 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBY17838.1 - 9.7e-81 269.6 0.2 6.5e-79 263.7 0.1 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBY17838.1 - 1.4e-58 197.3 0.0 5.7e-58 195.4 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBY17838.1 - 8.8e-46 154.9 0.0 8.6e-44 148.5 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBY17838.1 - 9.1e-43 146.6 11.2 9.1e-43 146.6 11.2 2.1 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CBY17838.1 - 3.7e-26 91.7 0.2 3e-25 88.8 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBY17838.1 - 1.5e-19 70.3 0.0 0.00016 21.7 0.0 6.4 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CBY17838.1 - 7.7e-17 61.3 0.2 7e-16 58.3 0.1 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 CBY17838.1 - 1.8e-05 25.2 0.2 3 8.3 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY17838.1 - 0.00049 20.4 0.6 0.98 9.7 0.0 4.8 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.22 CBY17838.1 - 0.00099 19.5 0.3 8.1 6.9 0.0 4.4 4 0 0 4 4 4 0 RNA helicase AAA_30 PF13604.6 CBY17838.1 - 0.0058 16.4 0.2 3.6 7.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CBY17838.1 - 0.0061 17.1 2.0 0.34 11.4 0.0 4.4 5 0 0 5 5 2 1 AAA domain AAA_24 PF13479.6 CBY17838.1 - 0.015 15.0 0.2 7.6 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 CBY17838.1 - 0.028 14.8 0.0 20 5.5 0.0 3.8 3 0 0 3 3 3 0 AAA ATPase domain EF-hand_6 PF13405.6 CBY17838.1 - 0.034 14.1 0.4 0.17 11.9 0.4 2.3 1 0 0 1 1 1 0 EF-hand domain TniB PF05621.11 CBY17838.1 - 0.1 12.0 0.1 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein T2SSE PF00437.20 CBY17838.1 - 0.11 11.5 0.3 0.64 9.0 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein ATPase_2 PF01637.18 CBY17838.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.6 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea Spc7 PF08317.11 CBY17838.1 - 0.17 10.7 29.5 0.055 12.3 4.2 4.4 4 0 0 4 4 4 0 Spc7 kinetochore protein ATG16 PF08614.11 CBY17838.1 - 0.34 11.1 16.1 1.1 9.4 1.7 4.2 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Phage_int_SAM_1 PF02899.17 CBY17838.1 - 0.85 10.0 2.3 18 5.7 0.6 3.6 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain BTB PF00651.31 CBY17839.1 - 4.5e-15 55.8 0.1 7.3e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 CBY17839.1 - 2.1e-06 27.8 13.0 0.00079 19.7 0.9 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY17839.1 - 0.00033 21.2 10.8 0.011 16.5 1.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY17839.1 - 0.0028 17.4 1.0 0.0028 17.4 1.0 2.2 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CBY17839.1 - 0.006 16.8 0.2 0.006 16.8 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY17839.1 - 0.016 15.5 4.0 0.091 13.2 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_12 PF18658.1 CBY17839.1 - 0.035 13.7 1.7 0.035 13.7 1.7 1.9 1 1 1 2 2 2 0 Zinc-finger C2H2-type DUF3342 PF11822.8 CBY17839.1 - 0.052 13.7 0.1 0.083 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) ADK_lid PF05191.14 CBY17839.1 - 0.055 13.5 0.6 0.12 12.4 0.6 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-H2C2_2 PF13465.6 CBY17839.1 - 0.077 13.5 1.5 0.077 13.5 1.5 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 CBY17839.1 - 0.085 13.2 6.1 1.9 8.9 1.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CBY17839.1 - 0.092 13.4 4.8 0.81 10.4 0.4 2.7 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 CBY17839.1 - 0.81 8.1 6.5 2.9 6.3 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Aminotran_4 PF01063.19 CBY17840.1 - 1.3e-29 103.7 0.0 1.6e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV N2227 PF07942.12 CBY17840.1 - 0.08 12.1 0.0 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 N2227-like protein DUF4224 PF13986.6 CBY17841.1 - 0.47 10.4 1.6 2 8.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4224) MRP-S24 PF14955.6 CBY17842.1 - 2.3e-21 76.2 0.3 7.5e-17 61.6 0.1 2.5 2 1 0 2 2 2 2 Mitochondrial ribosome subunit S24 Rtf2 PF04641.12 CBY17843.1 - 1.5e-60 204.8 6.4 2.4e-60 204.1 6.4 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger SET PF00856.28 CBY17844.1 - 9.3e-19 68.4 1.7 4.2e-18 66.3 0.3 2.5 2 1 0 2 2 2 1 SET domain N-SET PF11764.8 CBY17844.1 - 2.1e-05 24.7 1.4 0.00011 22.3 1.4 2.1 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 CBY17845.1 - 1.3e-17 64.7 0.2 1.3e-17 64.7 0.2 3.6 2 1 1 3 3 3 1 SET domain RRM_1 PF00076.22 CBY17845.1 - 0.045 13.6 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Syntaxin-6_N PF09177.11 CBY17846.1 - 2.3e-27 95.5 2.2 1.3e-26 93.0 0.2 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 CBY17846.1 - 1.9e-09 37.4 0.5 4.4e-09 36.2 0.5 1.7 1 0 0 1 1 1 1 SNARE domain T3SSipB PF16535.5 CBY17846.1 - 0.0069 16.9 0.9 0.26 11.8 0.7 2.1 2 0 0 2 2 2 1 Type III cell invasion protein SipB Sec20 PF03908.13 CBY17846.1 - 0.029 14.3 0.7 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Sec20 DUF745 PF05335.13 CBY17846.1 - 0.065 13.0 0.7 0.31 10.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) NPV_P10 PF05531.12 CBY17846.1 - 0.07 13.6 3.6 3.9 8.0 1.6 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 CBY17846.1 - 0.097 13.0 1.0 0.99 9.7 0.4 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCU PF04678.13 CBY17846.1 - 0.2 11.7 0.2 0.3 11.2 0.2 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter WD40 PF00400.32 CBY17847.1 - 1.2e-09 38.6 3.6 0.012 16.4 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Utp8 PF10395.9 CBY17847.1 - 0.0045 15.6 0.0 0.0079 14.8 0.0 1.3 1 0 0 1 1 1 1 Utp8 family BBS2_Mid PF14783.6 CBY17847.1 - 0.011 15.8 0.0 2.8 8.0 0.1 2.6 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 CBY17847.1 - 0.014 14.2 0.0 1.7 7.3 0.0 3.2 2 2 2 4 4 4 0 Nup133 N terminal like Nup160 PF11715.8 CBY17847.1 - 0.031 12.9 0.0 0.77 8.3 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DHH PF01368.20 CBY17848.1 - 4.4e-11 42.9 0.8 9.9e-11 41.8 0.1 1.7 2 0 0 2 2 2 1 DHH family DHHA2 PF02833.14 CBY17848.1 - 9.7e-08 32.3 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain Vps54 PF07928.12 CBY17849.1 - 4.3e-40 137.2 0.1 1.9e-39 135.2 0.1 2.1 1 0 0 1 1 1 1 Vps54-like protein ASL_C PF08328.11 CBY17849.1 - 0.0035 17.4 2.6 0.0051 16.9 0.4 2.5 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal DUF356 PF04009.12 CBY17849.1 - 0.037 14.3 0.6 0.11 12.7 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF356) CLU_N PF15044.6 CBY17849.1 - 0.12 12.8 1.6 0.68 10.3 0.2 2.9 2 1 0 2 2 2 0 Mitochondrial function, CLU-N-term Baculo_PEP_C PF04513.12 CBY17849.1 - 0.38 10.8 15.2 1.9 8.5 2.5 4.5 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.9 CBY17849.1 - 0.51 10.5 15.6 0.54 10.4 1.6 4.3 3 2 1 4 4 4 0 Golgi transport complex subunit 5 5_3_exonuc PF01367.20 CBY17849.1 - 0.59 10.8 4.6 1.2 9.8 0.0 3.4 3 1 1 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold Sulfotransfer_3 PF13469.6 CBY17850.1 - 0.022 15.1 0.0 0.075 13.4 0.0 1.8 2 1 0 2 2 2 0 Sulfotransferase family DUF3328 PF11807.8 CBY17850.1 - 0.064 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) TRAM_LAG1_CLN8 PF03798.16 CBY17851.1 - 7.5e-11 42.1 6.2 9.7e-11 41.8 6.2 1.1 1 0 0 1 1 1 1 TLC domain NAC PF01849.18 CBY17852.1 - 1e-13 51.0 0.0 3.1e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 NAC domain Ribosomal_L30 PF00327.20 CBY17852.1 - 0.029 14.3 0.4 0.051 13.5 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e AAA PF00004.29 CBY17853.1 - 2.9e-37 128.0 0.0 5.3e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY17853.1 - 1.3e-10 40.9 0.0 3.2e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBY17853.1 - 7.8e-09 35.4 0.2 3.6e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CBY17853.1 - 8.3e-07 28.9 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBY17853.1 - 0.00025 21.3 0.6 0.023 15.0 0.6 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CBY17853.1 - 0.00035 20.6 0.0 0.47 10.5 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CBY17853.1 - 0.0012 18.9 0.0 0.0061 16.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CBY17853.1 - 0.0012 18.1 0.1 0.002 17.4 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 CBY17853.1 - 0.0022 18.4 3.0 0.088 13.2 3.0 3.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CBY17853.1 - 0.017 14.7 0.1 0.59 9.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 CBY17853.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CBY17853.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBY17853.1 - 0.061 12.7 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CBY17853.1 - 0.075 12.5 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 CBY17853.1 - 0.088 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain ATPase PF06745.13 CBY17853.1 - 0.65 9.3 2.5 2.4 7.4 0.9 2.5 1 1 1 2 2 2 0 KaiC HNF-1A_C PF04813.12 CBY17854.1 - 0.035 14.9 0.7 0.046 14.5 0.6 1.4 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HSP90 PF00183.18 CBY17855.1 - 3.3e-09 36.2 0.0 3.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HSP90 PF00183.18 CBY17856.1 - 5.3e-79 266.5 2.7 6.3e-79 266.2 2.7 1.0 1 0 0 1 1 1 1 Hsp90 protein HBS1_N PF08938.10 CBY17856.1 - 0.16 12.3 0.2 0.16 12.3 0.2 2.9 3 0 0 3 3 3 0 HBS1 N-terminus HSP70 PF00012.20 CBY17857.1 - 2.7e-259 861.4 11.2 3.1e-259 861.2 11.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBY17857.1 - 1.6e-18 66.7 2.1 1.2e-17 63.7 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 CBY17857.1 - 0.00024 21.5 1.1 2.7 8.5 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 CBY17857.1 - 0.0029 17.1 0.1 0.57 9.6 0.0 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 CBY17857.1 - 0.023 14.4 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain WD40 PF00400.32 CBY17858.1 - 5e-12 46.1 14.2 0.0051 17.6 0.0 10.1 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY17858.1 - 9.2e-06 25.9 0.0 19 5.6 0.0 5.4 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Trypsin PF00089.26 CBY17861.1 - 3.2e-55 187.4 0.5 4.4e-55 186.9 0.5 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY17861.1 - 6.3e-07 30.4 0.1 1.2e-06 29.5 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Pkinase PF00069.25 CBY17862.1 - 2e-78 263.4 0.1 2.5e-78 263.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY17862.1 - 4.1e-38 131.2 0.2 2.4e-37 128.6 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY17862.1 - 1.2e-08 34.3 0.4 2.2e-08 33.5 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY17862.1 - 0.00049 20.1 0.0 0.0089 16.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY17862.1 - 0.0025 16.9 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.20 CBY17862.1 - 0.038 13.6 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CBY17862.1 - 0.05 13.0 0.2 0.099 12.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_15 PF00723.21 CBY17864.1 - 1.9e-66 224.7 0.1 9.3e-57 192.8 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 Prefoldin_2 PF01920.20 CBY17865.1 - 2.2e-06 27.6 2.3 3.1e-06 27.1 2.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit PP1c_bdg PF10488.9 CBY17865.1 - 0.0045 16.5 0.3 0.0049 16.4 0.3 1.2 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region RmuC PF02646.16 CBY17865.1 - 0.019 14.1 5.0 0.15 11.1 0.8 2.0 2 0 0 2 2 2 0 RmuC family Prefoldin PF02996.17 CBY17865.1 - 0.032 14.1 8.1 0.19 11.6 8.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 CBY17865.1 - 0.23 11.5 9.8 0.79 9.8 2.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.25 CBY17865.1 - 0.27 10.9 6.6 3.8 7.1 0.8 2.1 2 0 0 2 2 2 0 Syntaxin DUF1664 PF07889.12 CBY17865.1 - 0.31 11.1 3.8 2.7 8.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 CBY17865.1 - 0.39 11.2 5.9 7.6 7.0 1.5 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Osmo_CC PF08946.10 CBY17865.1 - 0.42 10.9 3.3 7.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF2443 PF10398.9 CBY17865.1 - 0.52 10.4 3.5 0.81 9.8 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) DivIC PF04977.15 CBY17865.1 - 1.1 9.0 6.3 4.2 7.2 3.7 2.1 2 0 0 2 2 2 0 Septum formation initiator LPP PF04728.13 CBY17865.1 - 1.3 9.5 8.4 0.99 9.8 1.2 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper WD40 PF00400.32 CBY17866.1 - 7.5e-19 67.7 14.9 6.4e-05 23.6 0.0 9.4 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY17866.1 - 6.6e-15 55.2 0.4 0.0016 18.7 0.0 6.1 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY17866.1 - 3.2e-07 30.0 0.1 0.14 11.5 0.0 3.5 3 0 0 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 CBY17866.1 - 0.037 13.0 0.1 0.33 9.9 0.1 2.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RPAP1_C PF08620.10 CBY17867.1 - 3.5e-19 68.7 0.0 7.9e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CBY17867.1 - 1.9e-14 53.2 3.0 4.7e-14 51.9 3.0 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal RTBV_P46 PF06216.11 CBY17870.1 - 0.022 13.7 1.3 0.032 13.1 1.3 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein FlaC_arch PF05377.11 CBY17870.1 - 0.049 14.0 0.7 0.049 14.0 0.7 3.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 CBY17870.1 - 0.094 12.6 8.7 0.98 9.3 1.3 3.5 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Phlebovirus_NSM PF07246.11 CBY17870.1 - 0.79 9.0 11.3 1.9 7.8 11.3 1.6 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1664 PF07889.12 CBY17870.1 - 3.1 7.8 9.7 0.19 11.8 3.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 CBY17870.1 - 3.3 7.9 26.3 0.022 14.9 15.8 2.3 2 1 1 3 3 3 0 Tropomyosin like ZapB PF06005.12 CBY17870.1 - 4.5 7.8 20.5 0.21 12.0 5.6 3.5 3 1 1 4 4 4 0 Cell division protein ZapB ERM PF00769.19 CBY17870.1 - 4.9 6.9 27.5 98 2.6 27.7 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4140 PF13600.6 CBY17870.1 - 6.6 7.2 15.5 4.6 7.8 2.7 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Phage_GPO PF05929.11 CBY17870.1 - 8.8 5.9 16.2 3.1 7.3 12.9 1.9 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Exo70 PF03081.15 CBY17871.1 - 3.1e-55 187.7 7.8 7.6e-55 186.5 7.8 1.6 1 0 0 1 1 1 1 Exo70 exocyst complex subunit TFIIB_C_1 PF18542.1 CBY17871.1 - 0.059 13.4 0.1 0.23 11.5 0.1 2.0 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 DASH_Dam1 PF08653.10 CBY17871.1 - 0.2 11.5 0.9 8.5 6.3 0.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 Laminin_II PF06009.12 CBY17871.1 - 0.84 9.6 15.9 8.5 6.4 1.3 4.4 3 1 1 4 4 4 0 Laminin Domain II DEAD PF00270.29 CBY17872.1 - 8.6e-37 126.6 0.2 1.7e-36 125.6 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY17872.1 - 1.2e-27 96.4 0.1 3.7e-27 94.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY17872.1 - 2.1e-05 24.6 0.1 0.00012 22.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBY17872.1 - 0.00065 19.1 1.8 0.015 14.6 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit PGM_PMM_I PF02878.16 CBY17873.1 - 1e-17 64.1 0.2 6.1e-08 32.5 0.0 3.1 2 1 1 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CBY17873.1 - 2.4e-10 40.4 0.4 8.2e-10 38.7 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CBY17873.1 - 3.7e-10 40.0 0.3 7.6e-10 39.0 0.3 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III MAGI_u1 PF16663.5 CBY17874.1 - 0.01 15.9 5.0 0.83 9.8 0.2 3.1 3 0 0 3 3 3 2 Unstructured region on MAGI Castor1_N PF18700.1 CBY17874.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Tweety PF04906.13 CBY17874.1 - 0.26 9.9 1.0 0.42 9.2 0.1 1.6 2 0 0 2 2 2 0 Tweety DUF5548 PF17702.1 CBY17875.1 - 0.042 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5548) mIF3 PF14877.6 CBY17876.1 - 0.047 13.3 0.5 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial translation initiation factor GDPD PF03009.17 CBY17879.1 - 1e-33 117.2 0.2 1.3e-33 116.9 0.2 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2326 PF10088.9 CBY17879.1 - 0.018 14.8 0.6 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) ASC PF00858.24 CBY17880.1 - 4.1e-53 180.9 14.3 5.9e-53 180.4 14.3 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DNA_primase_S PF01896.19 CBY17881.1 - 8.1e-45 153.0 0.7 1.4e-44 152.3 0.7 1.4 1 0 0 1 1 1 1 DNA primase small subunit Carbpep_Y_N PF05388.11 CBY17881.1 - 0.068 13.7 0.2 0.16 12.5 0.2 1.6 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Peptidase_M24 PF00557.24 CBY17882.1 - 4.5e-23 82.1 1.1 6.1e-23 81.6 0.8 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S25 PF03297.15 CBY17882.1 - 0.34 11.1 7.0 0.81 9.9 0.1 3.0 3 0 0 3 3 3 0 S25 ribosomal protein 7tm_1 PF00001.21 CBY17883.1 - 0.00047 19.6 0.1 0.00055 19.3 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF962 PF06127.11 CBY17883.1 - 0.056 13.5 0.2 0.084 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF962) DUF3671 PF12420.8 CBY17883.1 - 0.13 12.4 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function 7tm_1 PF00001.21 CBY17884.1 - 5.4e-06 25.9 2.5 6.7e-06 25.6 2.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SIS PF01380.22 CBY17885.1 - 3.6e-65 217.7 0.0 2.6e-36 124.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CBY17885.1 - 6.1e-15 55.6 0.0 1.3e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CBY17885.1 - 1e-09 38.3 0.0 2.8e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.6 CBY17885.1 - 0.00068 19.7 0.0 0.0069 16.4 0.0 2.4 2 0 0 2 2 2 1 SIS domain GATase_4 PF13230.6 CBY17885.1 - 0.0014 17.6 0.1 0.0035 16.3 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Not1 PF04054.15 CBY17886.1 - 7.2e-61 206.1 2.4 1.3e-60 205.3 0.4 2.3 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CBY17886.1 - 5.1e-56 189.6 1.8 1.5e-55 188.0 0.9 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 CBY17886.1 - 9.1e-31 106.8 3.0 2.8e-30 105.2 3.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CBY17886.1 - 1.7e-16 60.6 1.0 6.6e-16 58.7 1.0 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 CBY17886.1 - 1.1e-14 54.1 0.0 3.4e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3387 PF11867.8 CBY17886.1 - 0.0012 18.3 0.7 0.092 12.1 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3387) Vps5 PF09325.10 CBY17888.1 - 1e-72 244.5 8.4 1e-72 244.5 8.4 1.8 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 CBY17888.1 - 8.9e-17 61.1 0.0 3.2e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 CBY17888.1 - 0.0029 17.1 0.3 0.0078 15.7 0.3 1.8 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF3967 PF13152.6 CBY17889.1 - 0.19 11.5 0.2 0.37 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) ArfGap PF01412.18 CBY17890.1 - 1e-31 109.4 3.2 2.7e-31 108.0 3.2 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TUDOR PF00567.24 CBY17891.1 - 3e-10 40.2 0.0 1.2e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Tudor domain DUF3836 PF12930.7 CBY17891.1 - 0.028 14.2 0.2 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF3836) IF4E PF01652.18 CBY17892.1 - 1.1e-27 96.8 0.1 1.3e-27 96.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 CBY17893.1 - 2.1e-09 37.2 0.0 4e-09 36.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain IF4E PF01652.18 CBY17893.1 - 0.0095 15.7 0.1 0.062 13.1 0.1 2.0 1 1 0 2 2 2 1 Eukaryotic initiation factor 4E Pkinase_Tyr PF07714.17 CBY17893.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 CBY17893.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_6 PF08030.12 CBY17894.1 - 7.7e-25 87.8 0.0 2.5e-24 86.2 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CBY17894.1 - 1.5e-22 79.7 0.0 3.3e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CBY17894.1 - 2e-19 69.9 8.2 2e-19 69.9 8.2 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 CBY17894.1 - 0.12 13.1 0.0 0.37 11.5 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain YGGT PF02325.17 CBY17894.1 - 0.64 10.5 4.2 0.56 10.7 0.6 2.6 2 0 0 2 2 2 0 YGGT family Proteasome PF00227.26 CBY17895.1 - 1.4e-59 200.8 0.1 1.8e-59 200.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBY17895.1 - 1.3e-14 53.5 0.2 2.5e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ferric_reduct PF01794.19 CBY17896.1 - 5.5e-23 81.4 11.9 1.1e-22 80.5 11.9 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CBY17896.1 - 1.7e-21 76.4 0.0 3.5e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CBY17896.1 - 3.8e-21 75.8 0.0 5.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CBY17896.1 - 0.02 15.5 0.0 0.08 13.6 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBY17896.1 - 0.034 14.5 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Reticulon PF02453.17 CBY17897.1 - 0.0018 18.3 3.0 0.0029 17.6 3.0 1.2 1 0 0 1 1 1 1 Reticulon GCP_C_terminal PF04130.13 CBY17897.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal UPF0203 PF05254.12 CBY17898.1 - 1e-13 51.3 3.5 1.3e-13 50.9 3.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 CBY17898.1 - 0.017 15.5 0.9 0.08 13.3 0.9 1.9 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 CBY17898.1 - 0.021 14.9 8.1 0.13 12.3 0.3 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CBY17898.1 - 0.28 11.0 4.3 10 5.9 0.2 2.2 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Mannosyl_trans PF05007.13 CBY17899.1 - 3.9e-58 197.4 22.0 5.4e-58 196.9 22.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CBY17899.1 - 2.3e-13 50.0 32.1 9e-13 48.0 32.1 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U SAM_1 PF00536.30 CBY17900.1 - 1.8e-18 66.7 0.6 3.2e-18 65.9 0.1 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY17900.1 - 1.9e-15 56.7 0.2 3.9e-15 55.7 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 CBY17900.1 - 5.3e-11 42.2 0.2 1.8e-10 40.5 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY17900.1 - 2.7e-09 37.2 0.0 6.8e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SAM_3 PF18016.1 CBY17900.1 - 1.1e-06 28.3 0.2 2.2e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CBY17900.1 - 1.7e-06 27.9 0.2 3.2e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PDZ_2 PF13180.6 CBY17900.1 - 1.8e-05 25.0 0.1 0.00041 20.6 0.0 2.5 2 0 0 2 2 2 1 PDZ domain SAM_4 PF18017.1 CBY17900.1 - 0.0086 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 CBY17900.1 - 0.017 15.3 0.2 0.033 14.4 0.2 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DUF1143 PF06608.11 CBY17901.1 - 1.2e-05 25.4 0.3 2.4e-05 24.4 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) Glyco_hydro_9 PF00759.19 CBY17902.1 - 1e-204 680.6 19.1 1.2e-115 387.3 7.7 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 Homeodomain PF00046.29 CBY17904.1 - 1.2e-21 76.3 4.6 2.2e-21 75.4 4.6 1.4 1 0 0 1 1 1 1 Homeodomain DUF1589 PF07628.11 CBY17904.1 - 0.0086 16.2 1.3 0.12 12.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1589) Squash PF00299.18 CBY17905.1 - 0.065 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Squash family serine protease inhibitor Linker_histone PF00538.19 CBY17906.1 - 3.3e-26 91.5 0.8 3.3e-26 91.5 0.8 2.3 2 1 1 3 3 3 1 linker histone H1 and H5 family FANCD2OS PF15124.6 CBY17906.1 - 0.048 13.9 2.2 0.074 13.3 2.2 1.3 1 0 0 1 1 1 0 FANCD2 opposite strand protein HC2 PF07382.11 CBY17906.1 - 0.81 9.7 68.0 2 8.4 68.0 1.6 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Mucin PF01456.17 CBY17906.1 - 0.91 9.5 10.1 0.25 11.3 5.1 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein PHP PF02811.19 CBY17907.1 - 0.053 13.8 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 PHP domain Pkinase PF00069.25 CBY17908.1 - 3.3e-27 95.5 0.0 6.4e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY17908.1 - 3.1e-21 75.8 0.0 5.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY17908.1 - 0.00024 20.5 0.0 0.00054 19.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Presenilin PF01080.17 CBY17908.1 - 0.0013 17.5 7.3 0.0017 17.2 7.3 1.1 1 0 0 1 1 1 1 Presenilin Kdo PF06293.14 CBY17908.1 - 0.04 13.3 0.2 0.098 12.0 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SOG2 PF10428.9 CBY17908.1 - 3.4 6.7 18.1 4.9 6.2 18.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SLC12 PF03522.15 CBY17908.1 - 9.9 5.1 12.9 15 4.5 12.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 zinc_ribbon_16 PF17034.5 CBY17909.1 - 5.1e-08 33.2 15.3 9.9e-08 32.2 15.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family DUF3565 PF12088.8 CBY17909.1 - 0.089 12.8 2.9 0.13 12.2 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) zf-rbx1 PF12678.7 CBY17909.1 - 6.6 7.1 16.1 0.32 11.3 8.5 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain CENP-T_C PF15511.6 CBY17910.1 - 4.1e-08 33.3 0.1 5.5e-08 32.9 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY17910.1 - 6.6e-05 23.0 0.2 0.00012 22.1 0.1 1.6 1 1 1 2 2 2 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY17910.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY17910.1 - 0.00079 19.7 1.0 0.0029 17.9 0.1 2.0 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY17910.1 - 0.0013 19.1 0.5 0.0027 18.1 0.5 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY17910.1 - 0.036 14.2 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CBY17911.1 - 1.9e-08 34.8 0.1 2.4e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 CBY17911.1 - 0.037 14.5 0.1 0.055 14.0 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone_H2A_C PF16211.5 CBY17912.1 - 3.4e-17 61.9 2.1 7.8e-17 60.7 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY17912.1 - 2.4e-16 60.3 0.0 3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY17912.1 - 2.4e-05 24.5 0.0 3.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Shugoshin_N PF07558.11 CBY17913.1 - 0.018 14.9 2.7 0.09 12.7 0.6 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region GMP_PDE_delta PF05351.11 CBY17913.1 - 0.041 14.0 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 GMP-PDE, delta subunit Peptidase_S66 PF02016.15 CBY17913.1 - 0.044 13.9 0.2 0.13 12.4 0.1 1.8 2 1 0 2 2 2 0 LD-carboxypeptidase N-terminal domain Trimer_CC PF08954.11 CBY17913.1 - 0.51 9.9 3.6 0.21 11.2 0.7 1.8 2 0 0 2 2 2 0 Trimerisation motif ZapB PF06005.12 CBY17913.1 - 1.3 9.5 8.1 0.12 12.9 2.0 2.3 2 1 1 3 3 3 0 Cell division protein ZapB Trypsin PF00089.26 CBY17914.1 - 7.3e-37 127.3 0.4 7.7e-27 94.5 0.1 4.4 2 2 0 2 2 2 2 Trypsin PV-1 PF06637.11 CBY17915.1 - 0.0028 16.6 3.7 0.0045 15.9 3.7 1.2 1 0 0 1 1 1 1 PV-1 protein (PLVAP) RRM_1 PF00076.22 CBY17916.1 - 7.5e-10 38.5 0.3 0.0033 17.2 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAR_2 PF10455.9 CBY17916.1 - 0.018 14.2 4.8 0.035 13.3 4.8 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4283 PF14111.6 CBY17916.1 - 0.086 12.4 0.0 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) BRAP2 PF07576.12 CBY17916.1 - 0.12 12.6 0.5 0.44 10.8 0.5 2.0 1 1 0 1 1 1 0 BRCA1-associated protein 2 Remorin_C PF03763.13 CBY17917.1 - 0.013 15.3 3.5 0.047 13.6 3.2 2.1 1 1 0 1 1 1 0 Remorin, C-terminal region Nmad5 PF18757.1 CBY17917.1 - 0.16 12.1 6.0 0.085 13.1 3.7 1.8 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 TPR_2 PF07719.17 CBY17918.1 - 1.2e-14 53.2 6.3 0.00096 19.1 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY17918.1 - 4e-10 39.8 10.9 0.11 12.8 0.1 6.8 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY17918.1 - 1.3e-09 38.5 8.0 0.006 17.1 0.0 5.8 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY17918.1 - 1.1e-08 34.5 10.3 0.022 14.6 0.0 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY17918.1 - 4.5e-07 30.2 2.0 0.37 11.7 0.0 5.8 6 1 1 7 7 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY17918.1 - 2.1e-06 27.9 10.5 0.54 10.5 0.2 6.1 6 2 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBY17918.1 - 4.1e-05 23.3 2.9 11 6.4 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY17918.1 - 7.7e-05 23.3 0.0 2.4 8.9 0.0 4.8 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY17918.1 - 0.00036 21.0 6.0 6.3 7.7 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY17918.1 - 0.00055 19.4 0.6 0.66 9.3 0.0 3.9 4 0 0 4 4 4 1 MalT-like TPR region TPR_21 PF09976.9 CBY17918.1 - 0.0033 17.1 8.4 0.022 14.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CBY17918.1 - 0.0091 15.8 1.1 11 6.0 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY17918.1 - 0.037 14.2 12.5 4.5 7.7 0.2 6.5 8 0 0 8 8 5 0 Tetratricopeptide repeat GP46 PF07409.12 CBY17918.1 - 0.18 11.6 1.1 8.6 6.1 0.1 2.4 2 0 0 2 2 2 0 Phage protein GP46 DUF627 PF04781.12 CBY17918.1 - 0.23 11.5 3.6 13 5.8 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF627) MIT PF04212.18 CBY17918.1 - 5 7.3 6.3 2.6 8.2 0.1 3.4 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Sortilin-Vps10 PF15902.5 CBY17919.1 - 9.4e-59 199.4 7.8 2.2e-58 198.1 7.8 1.6 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CBY17919.1 - 4.1e-13 50.0 5.9 1e-12 48.7 5.9 1.6 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CBY17919.1 - 4.9e-06 25.8 18.3 1.6 9.1 0.0 6.3 5 0 0 5 5 5 3 BNR/Asp-box repeat BNR_2 PF13088.6 CBY17919.1 - 4.8e-05 22.8 0.2 0.036 13.4 0.0 3.3 3 0 0 3 3 3 1 BNR repeat-like domain PSII_BNR PF14870.6 CBY17919.1 - 0.05 12.8 0.9 0.75 9.0 0.0 3.1 5 0 0 5 5 5 0 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 CBY17919.1 - 0.28 11.4 10.2 27 5.2 0.0 6.3 7 0 0 7 7 7 0 BNR-Asp box repeat DUF4185 PF13810.6 CBY17919.1 - 1.9 7.6 9.0 0.69 9.1 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4185) CIAPIN1 PF05093.13 CBY17920.1 - 2.8e-21 75.9 17.0 4.7e-16 59.1 4.4 2.5 2 1 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis PilS PF08805.11 CBY17920.1 - 0.066 13.0 2.5 0.21 11.4 0.3 2.1 2 0 0 2 2 2 0 PilS N terminal DUF5556 PF17711.1 CBY17920.1 - 0.23 11.3 2.1 0.63 9.9 1.9 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5556) FMN_bind PF04205.14 CBY17920.1 - 0.24 12.0 1.5 15 6.2 0.0 2.4 2 0 0 2 2 2 0 FMN-binding domain PV-1 PF06637.11 CBY17922.1 - 0.002 17.0 6.2 0.0024 16.8 6.2 1.0 1 0 0 1 1 1 1 PV-1 protein (PLVAP) YbfN PF13982.6 CBY17922.1 - 0.0029 17.8 0.4 0.038 14.3 0.0 2.1 1 1 1 2 2 2 1 YbfN-like lipoprotein CorA PF01544.18 CBY17922.1 - 0.0031 16.9 3.0 0.0036 16.7 3.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.22 CBY17922.1 - 0.012 15.9 4.2 0.012 15.9 4.2 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 CBY17922.1 - 0.06 12.2 8.9 0.07 12.0 8.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 CBY17922.1 - 0.073 13.6 7.9 0.14 12.6 7.9 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region KxDL PF10241.9 CBY17922.1 - 0.13 12.6 4.6 0.09 13.1 2.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein JIP_LZII PF16471.5 CBY17922.1 - 0.55 10.4 8.6 0.21 11.8 4.7 2.0 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 CBY17922.1 - 0.7 9.9 5.7 2.5 8.2 4.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.6 CBY17922.1 - 0.75 9.3 8.3 0.2 11.2 2.4 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus SNF2_N PF00176.23 CBY17923.1 - 6.1e-59 199.5 1.7 1e-58 198.7 1.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY17923.1 - 3.2e-18 66.1 0.0 1.6e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBY17923.1 - 5.7e-05 22.4 0.2 0.00016 21.0 0.2 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CUE PF02845.16 CBY17923.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 CUE domain VEFS-Box PF09733.9 CBY17923.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.5 4 0 0 4 4 4 0 VEFS-Box of polycomb protein BAG PF02179.16 CBY17924.1 - 1.6e-11 44.5 1.0 2e-11 44.1 1.0 1.2 1 0 0 1 1 1 1 BAG domain RNR_N PF08343.10 CBY17924.1 - 0.018 15.0 0.7 1.3 9.1 0.1 2.5 1 1 1 2 2 2 0 Ribonucleotide reductase N-terminal Lentivirus_VIF PF05851.11 CBY17924.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.2 1 1 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Bystin PF05291.11 CBY17925.1 - 1.1e-117 392.5 1.4 1.5e-117 392.1 1.4 1.1 1 0 0 1 1 1 1 Bystin HEAT_2 PF13646.6 CBY17926.1 - 2.9e-06 27.6 0.1 0.0086 16.4 0.0 2.9 2 0 0 2 2 2 2 HEAT repeats Peptidase_M1_N PF17900.1 CBY17926.1 - 5.5e-06 26.7 0.1 0.0041 17.3 0.0 2.9 2 1 0 2 2 2 2 Peptidase M1 N-terminal domain HEAT PF02985.22 CBY17926.1 - 0.0044 17.2 1.8 3.7 8.0 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat eIF-3c_N PF05470.12 CBY17926.1 - 5.8 5.1 9.8 0.03 12.7 0.3 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mpp10 PF04006.12 CBY17927.1 - 4.2e-18 65.1 8.5 5.2e-18 64.8 8.5 1.2 1 0 0 1 1 1 1 Mpp10 protein Semialdhyde_dh PF01118.24 CBY17927.1 - 0.13 12.7 0.2 0.7 10.3 0.2 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Homeodomain PF00046.29 CBY17928.1 - 7.3e-19 67.4 4.4 1.5e-18 66.4 4.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY17928.1 - 0.023 14.6 0.3 0.061 13.2 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain Prenyltrans PF00432.21 CBY17929.1 - 2.2e-49 164.8 0.2 8.9e-11 41.3 0.3 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CBY17929.1 - 0.02 14.0 0.0 0.046 12.8 0.0 1.7 1 1 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CBY17929.1 - 0.14 11.2 0.0 1.1 8.3 0.0 2.3 1 1 2 3 3 3 0 Squalene-hopene cyclase N-terminal domain WWE PF02825.20 CBY17930.1 - 1e-13 51.6 4.3 1.5e-13 51.1 4.3 1.3 1 0 0 1 1 1 1 WWE domain zf-C3HC4_3 PF13920.6 CBY17930.1 - 1.7e-06 27.8 8.8 2.4e-06 27.3 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY17930.1 - 0.00095 19.0 13.0 0.0017 18.2 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY17930.1 - 0.0021 18.0 12.6 0.0025 17.8 7.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY17930.1 - 0.0027 18.0 12.5 0.0059 16.9 12.5 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CBY17930.1 - 0.0052 16.9 12.1 0.0093 16.1 12.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBY17930.1 - 0.006 16.4 12.8 0.012 15.4 12.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY17930.1 - 0.012 15.5 11.8 0.055 13.3 11.8 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY17930.1 - 0.042 13.8 15.6 0.2 11.6 15.7 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 CBY17930.1 - 4.9 7.0 9.9 16 5.4 0.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PALP PF00291.25 CBY17931.1 - 2.8e-71 240.4 0.5 3.3e-71 240.1 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WWE PF02825.20 CBY17931.1 - 7.7e-13 48.8 4.1 1.4e-12 48.0 4.1 1.4 1 0 0 1 1 1 1 WWE domain zf-C3HC4 PF00097.25 CBY17931.1 - 0.02 14.8 2.8 0.056 13.3 2.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY17931.1 - 0.045 13.6 3.3 0.092 12.6 3.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 CBY17931.1 - 0.071 13.4 0.7 0.2 11.9 0.7 1.7 1 0 0 1 1 1 0 zinc-ribbon Prok-RING_4 PF14447.6 CBY17931.1 - 0.14 12.1 4.1 0.28 11.1 4.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY17931.1 - 0.15 11.9 4.9 0.33 10.8 4.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY17931.1 - 0.26 11.6 4.1 0.86 10.0 4.1 2.0 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 CBY17931.1 - 0.79 9.9 3.5 1.8 8.8 3.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Nrap_D4 PF17405.2 CBY17932.1 - 4.3e-28 98.1 0.1 8.1e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 CBY17932.1 - 6.6e-19 68.5 0.1 1.5e-18 67.3 0.1 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D5 PF17406.2 CBY17932.1 - 6.6e-18 65.0 0.0 3.8e-17 62.5 0.0 2.2 3 0 0 3 3 3 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 CBY17932.1 - 2e-15 57.2 0.0 4.7e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 CBY17932.1 - 4e-06 26.7 0.2 0.00026 20.8 0.1 2.8 2 1 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 CBY17932.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Nrap protein domain 6 DUF3652 PF12372.8 CBY17933.1 - 4.2e-08 33.0 0.0 1.2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Huntingtin protein region HEAT PF02985.22 CBY17933.1 - 0.021 15.0 0.3 7.8 7.1 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat SK_channel PF03530.14 CBY17933.1 - 0.11 12.5 0.2 0.32 11.0 0.2 1.7 1 0 0 1 1 1 0 Calcium-activated SK potassium channel V-ATPase_H_C PF11698.8 CBY17933.1 - 0.14 12.2 5.5 0.84 9.8 0.1 4.8 5 1 2 7 7 7 0 V-ATPase subunit H DUF2781 PF10914.8 CBY17934.1 - 0.0052 17.2 0.1 0.0062 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Sigma_reg_N PF13800.6 CBY17934.1 - 0.024 14.9 1.7 0.05 13.9 0.1 2.0 1 1 1 2 2 2 0 Sigma factor regulator N-terminal DHHC PF01529.20 CBY17934.1 - 0.071 13.2 1.2 0.098 12.8 1.2 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase TMEM238 PF15125.6 CBY17934.1 - 1.4 9.2 12.0 3.8 7.8 12.0 1.7 1 1 0 1 1 1 0 TMEM238 protein family EzrA PF06160.12 CBY17935.1 - 0.00095 17.5 0.4 0.0012 17.2 0.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF5082 PF16888.5 CBY17935.1 - 0.0022 18.3 0.4 0.0029 17.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) TMF_TATA_bd PF12325.8 CBY17935.1 - 0.0023 18.1 2.6 0.0046 17.2 2.5 1.7 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding GAS PF13851.6 CBY17935.1 - 0.007 15.7 1.9 0.037 13.4 0.8 1.9 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding PspA_IM30 PF04012.12 CBY17935.1 - 0.0086 15.7 2.5 0.016 14.8 2.5 1.4 1 1 0 1 1 1 1 PspA/IM30 family Med9 PF07544.13 CBY17935.1 - 0.0086 16.2 1.0 2.4 8.3 0.0 2.3 2 1 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 CREPT PF16566.5 CBY17935.1 - 0.011 16.0 0.3 0.63 10.2 0.1 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PRKG1_interact PF15898.5 CBY17935.1 - 0.011 16.6 0.7 0.014 16.2 0.7 1.1 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ADIP PF11559.8 CBY17935.1 - 0.019 15.1 1.6 0.036 14.2 1.6 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 CBY17935.1 - 0.03 14.7 1.7 0.042 14.3 1.7 1.3 1 1 0 1 1 1 0 Centromere protein H (CENP-H) NPV_P10 PF05531.12 CBY17935.1 - 0.046 14.2 0.5 0.13 12.7 0.4 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SKA2 PF16740.5 CBY17935.1 - 0.11 12.3 2.6 1.6 8.5 1.5 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 CBY17935.1 - 0.11 13.0 2.8 0.21 12.1 2.8 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 CBY17935.1 - 0.13 12.8 1.4 13 6.5 0.0 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DivIC PF04977.15 CBY17935.1 - 0.21 11.4 5.6 0.21 11.4 1.3 2.0 1 1 1 2 2 2 0 Septum formation initiator Lectin_C PF00059.21 CBY17939.1 - 1.3e-45 154.5 15.2 3.3e-18 66.4 0.9 4.8 4 2 0 4 4 4 4 Lectin C-type domain Trefoil PF00088.18 CBY17939.1 - 2.2e-06 27.4 5.9 9.7e-06 25.4 5.9 2.2 1 0 0 1 1 1 1 Trefoil (P-type) domain UL45 PF05473.12 CBY17939.1 - 0.0059 16.3 7.7 0.12 12.0 0.0 4.3 4 1 0 4 4 4 2 UL45 protein, carbohydrate-binding C-type lectin-like A_deaminase PF00962.22 CBY17940.1 - 2.1e-97 326.4 0.0 6.1e-97 324.9 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Archease PF01951.16 CBY17940.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) RRM_1 PF00076.22 CBY17941.1 - 1.2e-47 159.5 0.0 4.9e-17 61.5 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY17941.1 - 1.8e-08 34.2 0.0 0.06 13.2 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBY17941.1 - 2.9e-08 33.7 0.4 2.7e-05 24.2 0.0 3.4 3 0 0 3 3 3 1 Limkain b1 RRM_3 PF08777.11 CBY17941.1 - 7e-07 29.2 0.2 0.057 13.5 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif RrnaAD PF00398.20 CBY17942.1 - 2.2e-61 207.2 0.1 3.1e-61 206.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CBY17942.1 - 1e-08 35.7 0.0 2.6e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY17942.1 - 1e-05 26.1 0.0 2.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY17942.1 - 0.00012 22.7 0.0 0.00025 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY17942.1 - 0.00097 18.7 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CBY17942.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CBY17942.1 - 0.0035 16.8 0.1 0.008 15.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.11 CBY17942.1 - 0.004 16.8 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 CBY17942.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 CBY17942.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.19 CBY17942.1 - 0.013 15.2 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CBY17942.1 - 0.021 14.6 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CBY17942.1 - 0.038 13.8 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 CBY17942.1 - 0.05 13.1 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 DREV PF05219.12 CBY17942.1 - 0.052 12.6 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Cons_hypoth95 PF03602.15 CBY17942.1 - 0.055 13.1 0.1 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 CBY17942.1 - 0.055 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 CBY17943.1 - 4.6e-32 111.1 0.0 5.9e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CBY17943.1 - 5.9e-09 36.5 0.0 9.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY17943.1 - 6.5e-06 26.7 0.0 1.1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY17943.1 - 5.9e-05 23.7 0.0 9.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY17943.1 - 0.00048 19.5 0.0 0.00059 19.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CBY17943.1 - 0.00095 18.7 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 CBY17943.1 - 0.0018 17.9 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 CBY17943.1 - 0.0022 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.18 CBY17943.1 - 0.0051 16.5 0.0 0.015 15.0 0.0 1.6 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 CMAS PF02353.20 CBY17943.1 - 0.0052 16.1 0.0 0.0067 15.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 CBY17943.1 - 0.0063 16.3 0.0 0.0085 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CBY17943.1 - 0.015 15.2 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CBY17943.1 - 0.019 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CBY17943.1 - 0.026 14.2 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DOT1 PF08123.13 CBY17943.1 - 0.026 14.1 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DREV PF05219.12 CBY17943.1 - 0.026 13.6 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.7 CBY17943.1 - 0.027 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CBY17943.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FAM195 PF14799.6 CBY17944.1 - 0.0057 17.0 0.0 0.0069 16.7 0.0 1.1 1 0 0 1 1 1 1 FAM195 family DUF4110 PF13422.6 CBY17944.1 - 0.017 15.2 0.2 0.027 14.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) MFS_1 PF07690.16 CBY17945.1 - 6e-23 81.3 21.3 3.6e-12 45.9 14.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 CBY17945.1 - 0.014 15.4 4.5 0.049 13.6 0.9 3.2 3 0 0 3 3 3 0 Bacteriophage P21 holin S MerC PF03203.14 CBY17945.1 - 0.034 14.6 0.1 0.034 14.6 0.1 4.3 2 2 2 4 4 4 0 MerC mercury resistance protein FtsL PF04999.13 CBY17945.1 - 0.39 10.7 2.1 2.2 8.3 0.3 2.5 2 0 0 2 2 2 0 Cell division protein FtsL CUB PF00431.20 CBY17948.1 - 3.4e-08 33.8 0.3 5.5e-08 33.1 0.3 1.3 1 0 0 1 1 1 1 CUB domain DUF4930 PF16284.5 CBY17948.1 - 0.026 14.5 0.1 0.048 13.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4930) Cupin_6 PF12852.7 CBY17949.1 - 0.56 9.9 2.6 26 4.5 0.0 2.9 3 0 0 3 3 3 0 Cupin Anoct_dimer PF16178.5 CBY17950.1 - 0.059 13.1 0.1 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin LRR_6 PF13516.6 CBY17951.1 - 1e-21 75.1 16.5 0.057 13.5 0.1 9.8 10 0 0 10 10 10 6 Leucine Rich repeat EF-hand_7 PF13499.6 CBY17951.1 - 4.2e-07 30.3 0.4 1.3e-06 28.8 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY17951.1 - 2.7e-06 26.9 0.5 0.00053 19.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBY17951.1 - 3.8e-06 26.7 0.4 1.5e-05 24.7 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY17951.1 - 8.3e-06 25.0 2.4 0.0046 16.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY17951.1 - 0.0005 19.4 2.1 0.032 13.7 0.2 2.6 2 0 0 2 2 2 1 EF hand LRR_1 PF00560.33 CBY17951.1 - 0.008 16.6 7.6 4.1 8.3 0.2 5.6 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 CBY17951.1 - 0.029 14.2 10.6 3 7.7 4.4 4.7 3 1 2 5 5 5 0 Leucine rich repeat LRR_2 PF07723.13 CBY17951.1 - 0.042 14.5 0.3 3.6 8.4 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 CBY17951.1 - 1.4 9.5 20.9 0.13 12.7 1.1 4.4 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Cullin_binding PF03556.15 CBY17952.1 - 1.4e-35 122.3 3.6 1.4e-35 122.3 3.6 1.6 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 CBY17952.1 - 9e-13 47.8 0.0 1.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CBY17952.1 - 0.05 13.2 0.2 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 TAP C-terminal domain DUF2748 PF10871.8 CBY17952.1 - 0.11 11.1 0.5 0.15 10.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) Bromodomain PF00439.25 CBY17953.1 - 1e-17 63.9 0.0 2.4e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain DUF3512 PF12024.8 CBY17953.1 - 1.5e-14 54.1 9.5 1.1e-11 44.6 0.1 4.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3512) TraF PF13728.6 CBY17953.1 - 0.036 13.9 4.3 0.084 12.7 4.3 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein AP3D1 PF06375.11 CBY17953.1 - 0.91 9.7 22.3 0.23 11.7 14.0 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Med19 PF10278.9 CBY17953.1 - 5 7.0 21.3 13 5.7 21.3 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TIP120 PF08623.10 CBY17954.1 - 1.1e-52 178.2 2.7 1.1e-52 178.2 2.7 4.2 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 CBY17954.1 - 8.1e-13 47.4 19.5 0.028 14.7 0.0 11.4 11 0 0 11 11 10 4 HEAT repeat HEAT_2 PF13646.6 CBY17954.1 - 1.7e-12 47.6 16.8 0.022 15.1 0.4 9.5 7 2 2 10 10 10 2 HEAT repeats HEAT_EZ PF13513.6 CBY17954.1 - 2.1e-09 37.6 10.0 0.71 10.4 0.0 8.5 9 0 0 9 9 8 2 HEAT-like repeat Adaptin_N PF01602.20 CBY17954.1 - 4e-08 32.3 34.1 0.00011 20.9 13.8 5.0 2 1 1 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.7 CBY17954.1 - 0.0014 18.7 38.1 0.95 9.5 0.3 8.4 3 3 4 8 8 8 2 non-SMC mitotic condensation complex subunit 1 FAD_SOX PF18371.1 CBY17954.1 - 0.0049 17.2 2.1 0.045 14.1 0.0 3.6 3 0 0 3 3 3 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase RNase_J_C PF17770.1 CBY17954.1 - 0.025 15.6 2.5 0.27 12.3 0.1 3.9 3 0 0 3 3 2 0 Ribonuclease J C-terminal domain RTP1_C1 PF10363.9 CBY17954.1 - 0.028 14.6 12.4 6.4 7.0 0.1 6.8 6 2 0 6 6 5 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_UF PF18817.1 CBY17954.1 - 0.029 14.7 0.0 0.28 11.5 0.0 2.8 1 0 0 1 1 1 0 Repeat of uncharacterized protein PH0542 FAM176 PF14851.6 CBY17954.1 - 0.061 13.0 0.7 0.16 11.6 0.7 1.7 1 0 0 1 1 1 0 FAM176 family HisK_sensor PF18698.1 CBY17954.1 - 0.067 13.6 4.9 0.12 12.8 2.0 2.7 2 0 0 2 2 2 0 Histidine kinase sensor domain TetR_C_36 PF18598.1 CBY17954.1 - 0.12 12.4 3.8 6.6 6.7 0.0 4.3 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF2457 PF10446.9 CBY17954.1 - 0.13 11.4 5.6 0.2 10.8 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 CBY17954.1 - 0.2 11.9 4.9 0.44 10.8 4.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.6 CBY17954.1 - 1 9.8 6.8 4.1 7.8 6.8 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal V-ATPase_H_C PF11698.8 CBY17954.1 - 1.6 8.8 19.6 2.1 8.5 0.0 6.6 5 2 3 8 8 7 0 V-ATPase subunit H NOA36 PF06524.12 CBY17954.1 - 4.1 6.7 9.0 8 5.7 9.0 1.4 1 0 0 1 1 1 0 NOA36 protein Symplekin_C PF12295.8 CBY17954.1 - 6.1 6.9 11.7 0.091 12.8 0.4 3.7 4 1 0 4 4 4 0 Symplekin tight junction protein C terminal CENP-B_dimeris PF09026.10 CBY17954.1 - 6.3 7.2 13.1 17 5.9 13.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NDUFV3 PF15880.5 CBY17955.1 - 0.00031 20.7 1.0 0.00047 20.1 1.0 1.3 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial PWI PF01480.17 CBY17956.1 - 2.4e-12 47.0 0.4 5.5e-12 45.8 0.4 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 CBY17956.1 - 1e-10 41.2 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) malic PF00390.19 CBY17957.1 - 1.8e-27 96.3 0.0 1.8e-21 76.7 0.1 2.4 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain Malic_M PF03949.15 CBY17957.1 - 2.9e-24 85.8 0.7 1.1e-23 83.9 0.7 1.9 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 CBY17957.1 - 7e-08 32.0 0.2 1.3e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.20 CBY17957.1 - 0.022 14.9 0.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus IGPS PF00218.21 CBY17957.1 - 0.04 13.1 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase DUF3825 PF12873.7 CBY17958.1 - 0.12 11.8 1.8 0.33 10.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3825) DUF1501 PF07394.12 CBY17959.1 - 0.069 12.2 7.2 0.082 12.0 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) KH_1 PF00013.29 CBY17960.1 - 1.5e-25 88.8 0.0 7.1e-13 48.2 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBY17960.1 - 2.4e-07 30.5 0.2 0.015 15.1 0.1 2.4 2 1 0 2 2 2 2 KH domain KH_4 PF13083.6 CBY17960.1 - 1.1e-05 25.2 2.2 0.11 12.4 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CBY17960.1 - 0.0032 17.5 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 2 NusA-like KH domain IFT57 PF10498.9 CBY17961.1 - 1.5e-45 155.8 5.7 1.6e-45 155.7 5.7 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 CBY17961.1 - 1.1e-05 25.5 9.9 1.1e-05 25.5 9.9 2.4 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CBY17961.1 - 7.9e-05 21.7 11.8 0.00014 20.8 11.5 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 CBY17961.1 - 0.00026 21.0 10.0 0.025 14.6 0.9 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) EzrA PF06160.12 CBY17961.1 - 0.00078 17.7 8.1 0.0021 16.3 7.9 1.8 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA DUF948 PF06103.11 CBY17961.1 - 0.005 17.1 4.7 0.78 10.0 1.7 2.5 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 CBY17961.1 - 0.006 16.1 12.2 0.023 14.1 10.8 1.9 1 1 1 2 2 2 1 Golgin subfamily A member 5 Fib_alpha PF08702.10 CBY17961.1 - 0.0087 16.3 8.4 1.2 9.3 1.6 2.3 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 CBY17961.1 - 0.019 15.2 8.7 0.92 9.8 2.7 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 CBY17961.1 - 0.022 15.1 7.4 9.3 6.7 0.0 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 CBY17961.1 - 0.025 14.6 13.8 0.41 10.8 1.1 3.6 2 1 1 3 3 2 0 TolA binding protein trimerisation KxDL PF10241.9 CBY17961.1 - 0.028 14.7 6.5 0.13 12.6 3.7 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1043 PF06295.12 CBY17961.1 - 0.033 14.2 2.7 0.059 13.4 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Exonuc_VII_L PF02601.15 CBY17961.1 - 0.04 13.5 5.8 0.056 13.0 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4404 PF14357.6 CBY17961.1 - 0.044 14.4 1.2 0.044 14.4 1.2 2.7 2 1 0 3 3 2 0 Domain of unknown function (DUF4404) IMD PF08397.11 CBY17961.1 - 0.049 13.0 4.1 0.084 12.2 3.8 1.5 1 1 0 1 1 1 0 IRSp53/MIM homology domain Nsp1_C PF05064.13 CBY17961.1 - 0.06 13.2 4.9 0.034 13.9 2.3 1.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region Nup88 PF10168.9 CBY17961.1 - 0.068 11.0 6.3 0.086 10.6 6.3 1.1 1 0 0 1 1 1 0 Nuclear pore component Bacillus_HBL PF05791.11 CBY17961.1 - 0.071 12.9 7.0 1 9.2 0.2 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PhaP_Bmeg PF09602.10 CBY17961.1 - 0.08 12.9 6.4 0.25 11.3 4.4 2.0 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) mit_SMPDase PF14724.6 CBY17961.1 - 0.1 10.6 0.3 0.13 10.3 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase DUF724 PF05266.14 CBY17961.1 - 0.11 12.3 10.4 0.12 12.2 5.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF724) UPF0184 PF03670.13 CBY17961.1 - 0.12 12.8 5.3 0.081 13.3 1.0 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) FadA PF09403.10 CBY17961.1 - 0.15 12.6 10.4 0.16 12.5 6.5 2.3 1 1 1 2 2 2 0 Adhesion protein FadA GreA_GreB_N PF03449.15 CBY17961.1 - 0.17 12.0 8.3 0.3 11.3 2.9 3.0 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal CorA PF01544.18 CBY17961.1 - 0.2 10.9 7.3 0.096 12.0 4.7 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Prominin PF05478.11 CBY17961.1 - 0.21 9.5 3.6 0.22 9.4 3.6 1.1 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 CBY17961.1 - 0.23 11.6 7.0 0.35 10.9 7.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sec34 PF04136.15 CBY17961.1 - 0.26 11.1 5.5 0.26 11.2 3.3 2.1 2 1 1 3 3 2 0 Sec34-like family CdvA PF18822.1 CBY17961.1 - 0.34 10.7 9.5 0.27 11.1 2.1 3.3 1 1 2 3 3 3 0 CdvA-like coiled-coil domain Seryl_tRNA_N PF02403.22 CBY17961.1 - 0.35 11.1 11.7 2.4 8.4 1.0 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CC2-LZ PF16516.5 CBY17961.1 - 0.37 11.2 10.8 17 5.9 1.3 3.4 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4200 PF13863.6 CBY17961.1 - 0.39 11.1 12.5 0.99 9.8 5.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 CBY17961.1 - 0.45 11.0 8.3 2.5 8.6 2.3 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 CBY17961.1 - 0.47 11.2 5.0 0.75 10.6 2.8 2.1 1 1 1 2 2 2 0 Occludin homology domain LUC7 PF03194.15 CBY17961.1 - 0.5 10.0 7.8 0.45 10.1 4.9 1.9 1 1 1 2 2 2 0 LUC7 N_terminus TMPIT PF07851.13 CBY17961.1 - 0.51 9.5 7.0 0.73 9.0 5.8 1.7 1 1 0 1 1 1 0 TMPIT-like protein FliD_N PF02465.18 CBY17961.1 - 0.59 10.9 5.9 0.28 11.9 2.6 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus GCN5L1 PF06320.13 CBY17961.1 - 0.72 10.0 8.9 3.1 8.0 6.0 2.6 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) Phage_GPO PF05929.11 CBY17961.1 - 0.72 9.4 7.8 1 8.9 1.6 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase YlqD PF11068.8 CBY17961.1 - 0.81 10.1 10.3 0.44 10.9 5.1 2.3 1 1 1 2 2 2 0 YlqD protein V_ATPase_I PF01496.19 CBY17961.1 - 0.84 7.5 4.7 1 7.2 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rx_N PF18052.1 CBY17961.1 - 1 9.7 6.3 3.4 8.0 0.3 2.6 1 1 0 2 2 2 0 Rx N-terminal domain WXG100 PF06013.12 CBY17961.1 - 1.3 9.3 6.3 16 5.8 2.0 3.4 2 1 1 3 3 2 0 Proteins of 100 residues with WXG Atg14 PF10186.9 CBY17961.1 - 1.6 7.8 12.4 9.6 5.2 12.1 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DegS PF05384.11 CBY17961.1 - 1.9 8.0 11.2 4.7 6.7 7.1 3.0 1 1 1 2 2 2 0 Sensor protein DegS CCDC-167 PF15188.6 CBY17961.1 - 1.9 8.9 10.3 9.6 6.6 6.3 3.0 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 FAM76 PF16046.5 CBY17961.1 - 2.1 7.6 7.2 3.1 7.1 7.2 1.3 1 0 0 1 1 1 0 FAM76 protein MCU PF04678.13 CBY17961.1 - 2.5 8.2 5.7 5 7.2 5.7 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DivIC PF04977.15 CBY17961.1 - 3.9 7.3 12.2 0.81 9.5 1.4 3.3 1 1 1 3 3 3 0 Septum formation initiator Cep57_MT_bd PF06657.13 CBY17961.1 - 4.2 7.9 9.0 1.4 9.4 1.2 3.1 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF16 PF01519.16 CBY17961.1 - 4.8 7.7 7.7 11 6.6 5.9 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 APG6_N PF17675.1 CBY17961.1 - 5.3 7.6 13.1 19 5.8 9.5 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Latarcin PF10279.9 CBY17961.1 - 6.8 7.2 7.3 26 5.3 7.3 2.3 1 1 0 1 1 1 0 Latarcin precursor HIP1_clath_bdg PF16515.5 CBY17961.1 - 6.8 7.4 12.6 4.5 8.0 4.2 2.9 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 IFT57 PF10498.9 CBY17962.1 - 1.2e-37 129.8 0.1 1.4e-37 129.6 0.1 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 EMP70 PF02990.16 CBY17963.1 - 2.6e-157 524.7 15.6 3.3e-157 524.3 15.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Ank_5 PF13857.6 CBY17965.1 - 2.1e-12 47.0 0.1 7.3e-08 32.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY17965.1 - 4.6e-12 46.4 0.2 2.8e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY17965.1 - 1.6e-10 40.3 0.1 0.00055 20.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CBY17965.1 - 8e-10 38.7 0.0 2.7e-06 27.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CBY17965.1 - 5.5e-08 33.2 0.0 0.00027 21.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 CBY17965.1 - 3.6e-07 30.2 10.5 7e-07 29.2 10.5 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 CBY17965.1 - 1.2 9.0 9.1 3.7 7.5 9.1 1.9 1 0 0 1 1 1 0 HIT zinc finger Ribonuc_2-5A PF06479.12 CBY17966.1 - 2.1e-09 37.6 0.7 2.1e-09 37.6 0.7 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A tRNA-synt_1e PF01406.19 CBY17967.1 - 1.2e-126 422.2 0.8 2.1e-126 421.4 0.8 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CBY17967.1 - 2.3e-05 23.4 8.5 0.002 17.0 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 CBY17967.1 - 0.0065 15.4 4.0 0.0082 15.1 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Dna2 PF08696.11 CBY17967.1 - 0.11 12.3 0.8 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 DNA replication factor Dna2 DALR_2 PF09190.11 CBY17967.1 - 0.43 11.1 0.0 0.43 11.1 0.0 2.4 2 0 0 2 2 2 0 DALR domain ALMT PF11744.8 CBY17967.1 - 3 6.6 4.5 4.6 6.0 4.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Meiosis_expr PF15163.6 CBY17968.1 - 1.5e-32 112.0 4.0 1.9e-32 111.8 4.0 1.1 1 0 0 1 1 1 1 Meiosis-expressed Mpv17_PMP22 PF04117.12 CBY17969.1 - 0.0073 16.5 0.8 0.019 15.2 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family WD40 PF00400.32 CBY17970.1 - 4.4e-19 68.5 5.3 4.8e-08 33.5 0.1 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY17970.1 - 1.3e-11 44.6 0.2 0.11 12.8 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY17970.1 - 0.0011 18.4 0.4 0.45 9.8 0.2 3.2 2 1 0 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 CBY17970.1 - 0.0016 18.4 0.1 3.7 7.6 0.1 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region EF-hand_7 PF13499.6 CBY17971.1 - 4.4e-22 78.3 3.3 3.5e-13 49.8 0.5 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBY17971.1 - 2.7e-21 73.4 10.1 1.9e-07 30.1 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBY17971.1 - 4.4e-19 66.7 3.7 3.4e-05 23.4 0.2 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CBY17971.1 - 4.8e-15 55.1 11.7 5.3e-07 29.4 0.3 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY17971.1 - 3.8e-13 48.3 11.4 4.3e-06 26.0 0.3 4.1 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 CBY17971.1 - 1.3e-05 25.1 5.7 0.32 11.0 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CBY17971.1 - 0.00038 20.7 0.2 0.012 16.0 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain PMBR PF09373.10 CBY17971.1 - 0.0018 18.3 0.1 3.7 7.9 0.0 4.2 5 0 0 5 5 5 1 Pseudomurein-binding repeat SPARC_Ca_bdg PF10591.9 CBY17971.1 - 0.0036 17.6 1.4 0.38 11.1 0.3 3.1 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region PET PF06297.14 CBY17972.1 - 7.5e-27 93.5 0.2 1.7e-26 92.4 0.2 1.6 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 CBY17972.1 - 3e-25 88.2 49.3 2.4e-10 40.5 7.9 4.5 4 1 0 4 4 4 3 LIM domain Dehydratase_SU PF02287.15 CBY17973.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Dehydratase small subunit Neur_chan_memb PF02932.16 CBY17976.1 - 1.8e-34 119.8 10.7 3.7e-30 105.7 6.8 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY17976.1 - 3.8e-26 91.9 0.6 5.9e-26 91.3 0.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain TSP_1 PF00090.19 CBY17977.1 - 4.4e-29 100.5 58.0 1.1e-07 32.0 4.4 5.9 4 1 1 5 5 5 5 Thrombospondin type 1 domain Kelch_1 PF01344.25 CBY17977.1 - 4.5e-09 35.7 6.4 0.03 13.9 0.2 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CBY17977.1 - 1e-08 34.8 8.0 0.13 12.2 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 CBY17977.1 - 1.2e-08 34.8 5.7 0.45 10.6 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CBY17977.1 - 2.2e-07 30.9 11.5 0.073 13.4 0.1 5.8 5 1 1 6 6 5 3 Kelch motif ATG16 PF08614.11 CBY17977.1 - 0.00066 20.0 2.4 0.00066 20.0 2.4 3.9 1 1 4 5 5 5 1 Autophagy protein 16 (ATG16) Kelch_4 PF13418.6 CBY17977.1 - 0.0014 18.5 2.7 30 4.7 0.0 4.5 4 0 0 4 4 4 0 Galactose oxidase, central domain BRE1 PF08647.11 CBY17977.1 - 0.0016 18.5 5.4 0.0016 18.5 5.4 5.3 3 1 2 6 6 5 1 BRE1 E3 ubiquitin ligase Kelch_3 PF13415.6 CBY17977.1 - 0.013 15.8 4.5 1.4 9.3 0.0 5.4 6 0 0 6 6 6 0 Galactose oxidase, central domain DUF641 PF04859.12 CBY17977.1 - 0.44 10.9 16.2 0.054 13.8 2.8 3.6 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) RPW8 PF05659.11 CBY17977.1 - 0.91 9.2 17.8 0.26 11.0 1.0 4.4 2 1 2 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2730 PF10805.8 CBY17977.1 - 1.5 9.0 15.9 21 5.3 0.4 5.5 5 1 2 7 7 7 0 Protein of unknown function (DUF2730) Ribosomal_S15 PF00312.22 CBY17977.1 - 2.9 8.2 7.3 9.1 6.6 0.0 3.5 3 0 0 3 3 3 0 Ribosomal protein S15 DUF4094 PF13334.6 CBY17977.1 - 3.2 8.2 10.3 0.29 11.6 0.7 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) LPP PF04728.13 CBY17977.1 - 3.7 8.0 22.8 2.7 8.4 0.0 6.6 6 1 1 7 7 7 0 Lipoprotein leucine-zipper Tropomyosin PF00261.20 CBY17977.1 - 4.6 6.5 17.9 0.23 10.8 0.5 3.4 2 1 0 2 2 2 0 Tropomyosin Laminin_II PF06009.12 CBY17977.1 - 6.5 6.8 26.5 1.5 8.9 2.3 4.1 4 0 0 4 4 4 0 Laminin Domain II DUF2207 PF09972.9 CBY17978.1 - 7.8 5.1 7.4 13 4.4 7.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ndc1_Nup PF09531.10 CBY17979.1 - 2.5 6.7 7.4 3.3 6.3 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-rbx1 PF12678.7 CBY17980.1 - 1.4e-25 89.4 16.0 1.8e-25 89.0 16.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY17980.1 - 4.3e-18 65.2 11.8 5.4e-18 64.8 11.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBY17980.1 - 3.1e-07 30.6 18.2 1.4e-05 25.3 18.2 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY17980.1 - 0.00015 21.6 15.1 0.0029 17.4 15.1 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY17980.1 - 0.00042 20.1 18.1 0.00077 19.2 12.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY17980.1 - 0.0015 18.3 14.5 0.007 16.2 8.3 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY17980.1 - 0.36 10.8 15.2 2.3 8.2 15.2 2.4 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 CBY17980.1 - 0.53 10.1 17.1 66 3.4 17.1 2.6 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 CBY17980.1 - 0.67 10.2 13.6 0.9 9.8 10.6 2.4 1 1 2 3 3 3 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CBY17980.1 - 1.2 8.8 18.6 0.12 12.0 6.2 2.6 1 1 2 3 3 3 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CBY17980.1 - 1.3 9.1 10.5 2.2 8.4 8.8 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.11 CBY17980.1 - 1.8 9.0 14.9 18 5.8 14.9 2.3 1 1 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 CBY17980.1 - 5.8 7.0 11.3 0.24 11.5 4.8 2.2 2 1 0 2 2 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 CBY17980.1 - 6.5 7.0 12.9 0.21 11.8 2.8 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Ribosomal_L23 PF00276.20 CBY17981.1 - 0.0085 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 DUF1016_N PF17761.1 CBY17981.1 - 0.013 15.6 0.3 0.026 14.7 0.3 1.4 1 0 0 1 1 1 0 DUF1016 N-terminal domain RCC1 PF00415.18 CBY17982.1 - 9.5e-16 58.2 0.2 3.6e-07 30.7 0.0 3.1 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.20 CBY17982.1 - 2.3e-13 49.2 39.0 9.3e-06 25.2 0.5 7.2 8 0 0 8 8 8 5 MORN repeat VPS9 PF02204.18 CBY17982.1 - 3e-09 37.0 0.1 2.5e-08 34.0 0.0 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain RCC1_2 PF13540.6 CBY17982.1 - 1.9e-05 24.3 7.7 1.5 8.8 0.1 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Cmc1 PF08583.10 CBY17983.1 - 0.018 15.1 5.3 0.25 11.4 2.2 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 CBY17983.1 - 0.26 11.3 3.8 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Hydrolase_3 PF08282.12 CBY17983.1 - 1.3 8.7 3.9 0.52 10.0 1.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Methyltransf_31 PF13847.6 CBY17984.1 - 1.2e-12 47.8 0.2 2.5e-12 46.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBY17984.1 - 2.8e-12 46.9 4.2 1.9e-10 41.0 4.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY17984.1 - 1.8e-07 30.9 0.2 3.1e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TRM13 PF05206.14 CBY17984.1 - 1.5e-05 24.7 6.4 0.0023 17.5 1.8 3.5 2 1 1 3 3 3 2 Methyltransferase TRM13 Methyltransf_25 PF13649.6 CBY17984.1 - 2.6e-05 24.9 0.2 5.3e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CBY17984.1 - 0.00075 19.0 0.0 0.0024 17.4 0.0 1.9 1 0 0 1 1 1 1 Putative methyltransferase Met_10 PF02475.16 CBY17984.1 - 0.0028 17.4 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.18 CBY17984.1 - 0.0078 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 CBY17984.1 - 0.099 12.6 0.2 0.23 11.4 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase domain GST_C PF00043.25 CBY17984.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M60_C PF18630.1 CBY17985.1 - 0.044 13.9 0.0 18 5.6 0.0 2.7 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain Homeodomain PF00046.29 CBY17986.1 - 2.7e-23 81.6 5.6 6.8e-23 80.3 5.6 1.7 1 0 0 1 1 1 1 Homeodomain Phospholip_A2_1 PF00068.19 CBY17987.1 - 0.0006 20.3 0.1 0.00091 19.7 0.1 1.3 1 0 0 1 1 1 1 Phospholipase A2 DUF2738 PF10927.8 CBY17987.1 - 0.025 13.7 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) zf-RING_2 PF13639.6 CBY17988.1 - 2.5e-11 43.7 7.3 2.5e-11 43.7 7.3 1.9 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 CBY17988.1 - 1.1e-10 41.7 7.0 1.1e-10 41.7 7.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBY17988.1 - 9e-10 38.2 8.1 9e-10 38.2 8.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY17988.1 - 2.2e-07 30.6 3.9 2.2e-07 30.6 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY17988.1 - 6e-07 29.2 6.7 6e-07 29.2 6.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY17988.1 - 1.3e-06 28.2 5.7 1.3e-06 28.2 5.7 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 CBY17988.1 - 5.5e-06 26.0 4.9 1.3e-05 24.9 4.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBY17988.1 - 1.6e-05 24.9 3.4 4.1e-05 23.5 3.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CBY17988.1 - 8.7e-05 22.1 5.1 0.00021 20.9 5.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CBY17988.1 - 0.00012 22.1 4.4 0.00025 21.1 4.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBY17988.1 - 0.00058 19.7 5.6 0.0015 18.4 5.6 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 CBY17988.1 - 0.00093 19.3 6.9 0.00093 19.3 6.9 1.9 2 0 0 2 2 1 1 RING-variant domain zf-HC5HC2H_2 PF13832.6 CBY17988.1 - 0.054 13.7 2.6 0.081 13.1 1.6 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-Nse PF11789.8 CBY17988.1 - 0.087 12.7 1.5 0.23 11.3 1.5 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 CBY17988.1 - 0.23 11.5 10.2 1.1 9.4 0.5 2.7 2 1 0 2 2 2 0 Double zinc ribbon FANCL_C PF11793.8 CBY17988.1 - 0.36 11.1 7.4 1.5 9.0 7.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Mucin-like PF16058.5 CBY17988.1 - 0.4 10.8 5.0 0.95 9.6 5.0 1.6 1 0 0 1 1 1 0 Mucin-like zf-RING_10 PF16685.5 CBY17988.1 - 5.7 7.2 10.1 0.38 10.9 3.7 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zn-ribbon_8 PF09723.10 CBY17988.1 - 5.7 7.1 10.2 8.8 6.5 2.3 2.9 2 1 0 2 2 2 0 Zinc ribbon domain PHD PF00628.29 CBY17988.1 - 8.4 6.4 17.2 1.2 9.0 6.7 2.4 2 0 0 2 2 2 0 PHD-finger UPAR_LY6_2 PF16975.5 CBY17989.1 - 0.00014 22.0 28.0 0.29 11.4 6.0 3.2 1 1 2 3 3 3 3 Ly6/PLAUR domain-containing protein 6, Lypd6 VP4_2 PF08935.10 CBY17989.1 - 0.37 11.4 3.7 21 5.8 0.1 2.9 1 1 2 3 3 3 0 Viral protein VP4 subunit PDZ PF00595.24 CBY17992.1 - 8.2e-13 48.5 0.0 1.7e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 CBY17992.1 - 3.7e-12 47.2 2.2 3.7e-12 47.2 2.2 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 CBY17992.1 - 1.8e-07 30.9 0.1 4e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY17992.1 - 2.4e-05 24.6 0.0 4.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain eIF3_subunit PF08597.10 CBY17992.1 - 3.9 7.3 13.9 24 4.7 13.9 2.0 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Pkinase_Tyr PF07714.17 CBY17993.1 - 2e-88 296.0 0.0 3.2e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY17993.1 - 5.5e-45 153.8 0.0 8.7e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.19 CBY17993.1 - 2.7e-36 125.3 5.9 4.4e-36 124.6 5.9 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain fn3 PF00041.21 CBY17993.1 - 1.5e-18 66.9 0.8 7.8e-11 42.2 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain Haspin_kinase PF12330.8 CBY17993.1 - 8.8e-05 21.6 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain cEGF PF12662.7 CBY17993.1 - 0.0035 17.2 6.3 0.11 12.4 0.8 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like Pkinase_fungal PF17667.1 CBY17993.1 - 0.0074 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Ephrin_rec_like PF07699.13 CBY17993.1 - 0.02 14.6 1.5 0.057 13.2 1.5 1.8 1 0 0 1 1 1 0 Putative ephrin-receptor like FAM176 PF14851.6 CBY17993.1 - 0.036 13.7 0.1 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 FAM176 family Kinase-like PF14531.6 CBY17993.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CBY17993.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM154 PF15102.6 CBY17993.1 - 0.09 12.7 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family EB PF01683.18 CBY17993.1 - 1.1 9.6 11.5 0.29 11.5 1.6 2.8 2 0 0 2 2 2 0 EB module EPL1 PF10513.9 CBY17994.1 - 0.0033 17.8 0.2 0.0033 17.8 0.2 1.9 1 1 0 2 2 2 1 Enhancer of polycomb-like SirA PF10747.9 CBY17994.1 - 0.13 12.6 4.6 0.15 12.4 2.1 2.4 1 1 1 2 2 2 0 Sporulation inhibitor of replication protein SirA FAD_binding_7 PF03441.14 CBY17995.1 - 1.3e-60 204.4 1.1 2e-60 203.7 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CBY17995.1 - 7.1e-38 130.2 0.0 1.1e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DnaJ_C PF01556.18 CBY17996.1 - 3.6e-32 111.5 0.1 4.8e-32 111.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain Thioredoxin PF00085.20 CBY17996.1 - 2.3e-22 78.9 0.0 3.8e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBY17996.1 - 7.7e-07 29.5 0.3 1.3e-05 25.6 0.3 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY17996.1 - 0.0012 19.2 0.1 0.035 14.4 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like Redoxin PF08534.10 CBY17996.1 - 0.0067 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 CBY17996.1 - 0.0097 15.3 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CBY17996.1 - 0.092 12.9 0.1 0.22 11.7 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like WD40 PF00400.32 CBY17997.1 - 2.2e-32 110.5 8.5 7.9e-06 26.5 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY17997.1 - 1e-06 28.9 0.2 1.8 9.0 0.0 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY17997.1 - 0.0004 20.3 0.7 0.041 13.8 0.1 2.8 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBY17997.1 - 0.051 12.5 0.1 11 4.9 0.0 3.4 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein KIAA1430 PF13879.6 CBY17998.1 - 0.022 15.5 4.4 0.024 15.4 4.4 1.1 1 0 0 1 1 1 0 KIAA1430 homologue ATP-synt_E PF05680.12 CBY17998.1 - 0.1 12.9 1.3 0.12 12.7 1.3 1.1 1 0 0 1 1 1 0 ATP synthase E chain Arf PF00025.21 CBY17999.1 - 2.8e-31 108.3 0.2 6.5e-24 84.3 0.1 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 CBY17999.1 - 0.0014 18.1 0.0 0.0044 16.5 0.1 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit 6PF2K PF01591.18 CBY17999.1 - 0.0063 15.8 0.1 0.0092 15.3 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase G-alpha PF00503.20 CBY17999.1 - 0.029 13.5 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Roc PF08477.13 CBY17999.1 - 0.034 14.4 0.1 0.052 13.8 0.1 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY17999.1 - 0.19 11.3 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 Ras family BIV_Env PF05858.12 CBY18001.1 - 0.027 12.7 0.2 0.076 11.2 0.8 1.5 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) Transcrip_reg PF01709.20 CBY18003.1 - 1e-12 48.0 7.7 1.1e-11 44.7 7.7 2.0 1 1 0 1 1 1 1 Transcriptional regulator DUF1818 PF08848.11 CBY18003.1 - 0.12 12.4 0.2 1.3 9.1 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1818) TFIIF_beta_N PF17683.1 CBY18003.1 - 0.14 12.8 0.5 0.75 10.5 0.0 2.0 2 0 0 2 2 2 0 TFIIF, beta subunit N-terminus Glutaredoxin PF00462.24 CBY18004.1 - 0.0038 17.4 3.2 0.0056 16.9 0.0 3.0 2 1 0 2 2 2 1 Glutaredoxin DnaJ_CXXCXGXG PF00684.19 CBY18004.1 - 0.048 14.0 4.5 0.048 14.0 4.5 2.2 1 1 1 2 2 2 0 DnaJ central domain Ntox1 PF15500.6 CBY18004.1 - 0.14 12.6 0.8 0.32 11.4 0.8 1.6 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 TackOD1 PF18551.1 CBY18004.1 - 1.4 8.6 8.8 0.36 10.5 4.2 2.2 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Zn_Tnp_IS1595 PF12760.7 CBY18004.1 - 2.5 8.1 9.2 24 5.0 9.5 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 CBY18004.1 - 2.9 7.5 7.9 0.67 9.5 2.6 2.6 1 1 1 2 2 2 0 TFIIB zinc-binding RRM_1 PF00076.22 CBY18005.1 - 9.9e-16 57.3 0.0 1.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec62 PF03839.16 CBY18005.1 - 0.012 15.1 3.0 0.017 14.6 3.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RAP1 PF07218.11 CBY18005.1 - 0.058 11.7 0.3 0.075 11.3 0.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ThrE_2 PF12821.7 CBY18005.1 - 0.061 13.5 1.8 0.091 12.9 1.8 1.3 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE V_ATPase_I PF01496.19 CBY18005.1 - 0.89 7.4 3.5 1.1 7.1 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3959 PF13105.6 CBY18005.1 - 5.7 6.4 5.9 9.8 5.6 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF417 PF04224.12 CBY18006.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF417 PWI PF01480.17 CBY18006.1 - 0.015 15.6 0.4 0.015 15.6 0.4 2.5 2 0 0 2 2 2 0 PWI domain Sugar_tr PF00083.24 CBY18007.1 - 4.6e-32 111.5 19.7 7.1e-32 110.8 19.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY18007.1 - 1.4e-22 80.1 22.9 1.4e-22 80.1 22.9 1.8 3 0 0 3 3 3 1 Major Facilitator Superfamily PC_rep PF01851.22 CBY18008.1 - 7e-06 26.2 0.9 0.37 11.3 0.0 5.2 5 0 0 5 5 5 2 Proteasome/cyclosome repeat Gam PF06064.11 CBY18009.1 - 0.0012 19.1 0.0 0.003 17.7 0.0 1.7 2 0 0 2 2 2 1 Host-nuclease inhibitor protein Gam Astacin PF01400.24 CBY18010.1 - 7.1e-23 81.2 5.4 6.9e-18 65.0 1.3 4.1 2 2 1 3 3 3 2 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY18010.1 - 0.017 15.3 2.3 0.053 13.7 2.3 1.8 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Ribosomal_S8e PF01201.22 CBY18011.1 - 7.5e-51 171.9 1.0 9e-51 171.6 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Acetyltransf_16 PF05301.11 CBY18012.1 - 1.6e-59 200.6 0.0 2.1e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_10 PF13673.7 CBY18012.1 - 0.00065 19.6 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY18012.1 - 0.0016 18.8 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY18012.1 - 0.0026 18.0 0.0 0.0045 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF676 PF05057.14 CBY18013.1 - 1.1e-33 116.6 0.0 1.9e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CBY18013.1 - 1.9e-08 34.4 0.0 3.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 CBY18013.1 - 0.028 15.0 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioredoxin PF00085.20 CBY18014.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBY18014.1 - 0.048 14.1 0.1 0.78 10.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain TraF PF13728.6 CBY18014.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Peptidase_M20 PF01546.28 CBY18015.1 - 4.3e-34 118.0 0.0 5.6e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBY18015.1 - 6.2e-15 55.0 0.0 1.6e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBY18015.1 - 0.00038 20.2 0.0 0.00083 19.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Myotub-related PF06602.14 CBY18016.1 - 3.3e-56 190.7 0.1 6.2e-56 189.8 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 CBY18016.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Sulfatase PF00884.23 CBY18017.1 - 5.8e-68 229.6 0.1 9.8e-68 228.8 0.1 1.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY18017.1 - 0.081 12.5 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase EF-hand_7 PF13499.6 CBY18018.1 - 7.6e-11 42.3 8.5 2.7e-08 34.1 2.6 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY18018.1 - 3.2e-09 35.7 5.4 0.00014 21.2 0.2 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY18018.1 - 6.8e-09 35.0 5.1 1.6e-05 24.4 0.6 4.2 4 1 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY18018.1 - 8.5e-05 21.9 4.8 0.00025 20.4 0.1 3.7 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 CBY18018.1 - 0.0042 16.9 13.6 0.013 15.3 2.5 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CBY18018.1 - 0.012 15.9 0.2 0.65 10.4 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain U3_assoc_6 PF08640.11 CBY18018.1 - 0.018 15.1 1.7 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 PTS_2-RNA PF01885.16 CBY18018.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Caleosin PF05042.13 CBY18018.1 - 0.063 13.2 1.0 0.8 9.6 0.0 2.6 2 1 1 3 3 3 0 Caleosin related protein RRM_1 PF00076.22 CBY18019.1 - 1.5e-36 124.0 0.0 4.7e-18 64.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY18019.1 - 0.00017 21.2 0.0 0.028 14.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY18019.1 - 0.019 15.1 0.0 8.7 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif RNA_bind PF08675.11 CBY18019.1 - 0.021 14.9 0.0 2 8.5 0.0 2.8 2 1 0 2 2 2 0 RNA binding domain Astacin PF01400.24 CBY18020.1 - 2.8e-09 36.8 0.0 2.8e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY18020.1 - 1.3e-05 25.3 6.0 1.3e-05 25.3 6.0 3.0 3 0 0 3 3 3 1 Calcium-binding EGF domain UPF0054 PF02130.17 CBY18020.1 - 0.21 11.4 0.5 7 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 CO_dh PF02552.16 CBY18021.1 - 0.13 12.0 0.7 0.18 11.5 0.7 1.2 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Mlf1IP PF10248.9 CBY18021.1 - 0.21 11.6 1.2 1.4 8.8 0.6 2.0 1 1 1 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein CIDR1_gamma PF18562.1 CBY18021.1 - 1.2 9.3 6.1 1.6 8.9 5.0 1.9 2 1 0 2 2 2 0 Cysteine-Rich Interdomain Region 1 gamma Peptidase_M10 PF00413.24 CBY18022.1 - 4.7e-49 166.3 0.0 6.2e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.8 CBY18022.1 - 0.00072 18.3 0.1 0.00096 17.9 0.1 1.1 1 0 0 1 1 1 1 Putative peptidase family Astacin PF01400.24 CBY18022.1 - 0.0013 18.4 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4953 PF16313.5 CBY18022.1 - 0.017 14.3 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 CBY18022.1 - 0.019 13.9 0.1 0.034 13.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.6 CBY18022.1 - 0.023 14.3 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CBY18022.1 - 0.062 13.4 0.1 0.096 12.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY18022.1 - 0.068 13.7 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 CBY18022.1 - 0.15 12.1 0.0 0.5 10.5 0.0 1.7 1 1 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M54 PF07998.11 CBY18022.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Ldl_recept_a PF00057.18 CBY18023.1 - 0.00015 21.9 9.9 0.00015 21.9 9.9 4.0 3 1 0 3 3 3 1 Low-density lipoprotein receptor domain class A Trypsin PF00089.26 CBY18025.1 - 1.6e-42 145.9 0.6 1.8e-42 145.6 0.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CBY18026.1 - 1.2e-60 205.1 0.1 3.7e-58 196.9 0.0 2.4 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CBY18026.1 - 1.1e-05 26.4 0.0 2.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain p47_phox_C PF08944.11 CBY18027.1 - 0.15 11.5 1.5 0.32 10.4 1.5 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Cnn_1N PF07989.11 CBY18028.1 - 0.007 16.5 1.9 0.0078 16.3 1.9 1.2 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 SRP_TPR_like PF17004.5 CBY18028.1 - 0.012 15.6 0.2 0.012 15.6 0.2 1.1 1 0 0 1 1 1 0 Putative TPR-like repeat NYD-SP28_assoc PF14775.6 CBY18028.1 - 0.025 14.7 0.9 0.038 14.1 0.1 1.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Myc-LZ PF02344.15 CBY18028.1 - 0.14 12.2 1.7 0.22 11.6 1.7 1.3 1 0 0 1 1 1 0 Myc leucine zipper domain CytochromB561_N PF09786.9 CBY18030.1 - 0.15 11.0 1.6 0.15 11.1 1.6 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Sulfotransfer_2 PF03567.14 CBY18031.1 - 5.9e-05 23.1 1.0 0.00061 19.8 0.0 2.5 2 1 0 2 2 2 1 Sulfotransferase family DUF16 PF01519.16 CBY18031.1 - 0.081 13.4 2.2 0.55 10.7 0.3 2.9 2 2 1 3 3 3 0 Protein of unknown function DUF16 Lectin_N PF03954.14 CBY18031.1 - 0.097 12.4 0.6 0.19 11.5 0.6 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Spectrin_like PF18373.1 CBY18031.1 - 8.6 6.5 6.4 1.9 8.6 0.8 2.6 3 0 0 3 3 3 0 Spectrin like domain CUB PF00431.20 CBY18032.1 - 3.6e-07 30.5 0.3 6.7e-05 23.2 0.1 2.3 1 1 1 2 2 2 2 CUB domain Sulfotransfer_2 PF03567.14 CBY18033.1 - 1.7e-36 126.5 0.6 2.2e-36 126.1 0.6 1.2 1 0 0 1 1 1 1 Sulfotransferase family CBS PF00571.28 CBY18034.1 - 3.5e-29 101.0 0.1 1.9e-07 31.4 0.1 4.4 4 0 0 4 4 4 4 CBS domain GARS_N PF02844.15 CBY18034.1 - 0.11 13.3 0.0 0.59 11.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Exo_endo_phos PF03372.23 CBY18036.1 - 1.4e-16 60.7 0.0 4.1e-16 59.2 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 CBY18036.1 - 5.5e-09 35.7 16.9 4e-08 32.9 13.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY18036.1 - 2.3e-07 31.0 12.8 7.8e-05 23.0 5.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY18036.1 - 1.9 9.3 15.3 5.8 7.9 1.0 4.8 3 1 0 3 3 3 0 Leucine Rich Repeat Ham1p_like PF01725.16 CBY18037.1 - 1.2e-47 162.3 0.0 1.3e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family KH_1 PF00013.29 CBY18038.1 - 2.2e-54 181.1 9.4 9.8e-17 60.5 0.1 4.2 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 CBY18038.1 - 2.9e-17 62.3 4.6 0.00012 21.8 0.1 4.3 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 CBY18038.1 - 1.2e-12 47.5 1.8 0.01 15.7 0.0 4.4 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 CBY18038.1 - 4.9e-10 38.7 26.6 6.1e-07 28.8 5.9 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_5 PF13184.6 CBY18038.1 - 0.01 15.9 9.7 1.7 8.8 0.1 4.3 4 0 0 4 4 4 0 NusA-like KH domain STAT_alpha PF01017.20 CBY18039.1 - 3.3e-37 128.0 15.2 3.3e-37 128.0 15.2 2.4 2 1 0 2 2 2 1 STAT protein, all-alpha domain STAT_bind PF02864.15 CBY18039.1 - 3.5e-37 127.9 0.9 8.5e-37 126.7 0.0 2.1 2 1 1 3 3 3 1 STAT protein, DNA binding domain STAT_int PF02865.17 CBY18039.1 - 1.2e-30 106.5 3.0 1.2e-30 106.5 3.0 2.3 2 1 1 3 3 3 1 STAT protein, protein interaction domain SH2 PF00017.24 CBY18039.1 - 1.5e-08 34.6 0.0 5e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 SH2 domain DUF2014 PF09427.10 CBY18039.1 - 0.02 14.3 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Pro_isomerase PF00160.21 CBY18040.1 - 3.1e-39 134.8 1.6 4e-39 134.4 0.2 1.9 1 1 1 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2326 PF10088.9 CBY18040.1 - 0.0077 16.0 0.7 0.029 14.1 0.8 1.9 2 0 0 2 2 2 1 Uncharacterised protein conserved in bacteria (DUF2326) zf-C2H2_4 PF13894.6 CBY18041.1 - 2e-10 40.6 19.0 0.025 15.4 0.9 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY18041.1 - 1.3e-07 31.7 21.5 0.1 13.1 0.1 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY18041.1 - 8.1e-05 22.9 21.2 0.045 14.2 0.8 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY18041.1 - 0.047 14.0 17.3 1.1 9.6 0.1 4.8 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY18041.1 - 0.048 13.7 24.9 0.055 13.5 0.3 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 CBY18041.1 - 0.12 11.9 3.4 1.4 8.5 0.3 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding zf-met PF12874.7 CBY18041.1 - 0.47 10.9 13.3 6.9 7.2 0.1 4.8 4 1 1 5 5 5 0 Zinc-finger of C2H2 type UPF0515 PF15135.6 CBY18041.1 - 0.61 9.4 9.7 0.044 13.1 4.4 1.8 1 1 1 2 2 2 0 Uncharacterised protein UPF0515 C1_4 PF07975.12 CBY18041.1 - 1.1 9.5 12.5 0.21 11.9 1.3 2.9 1 1 1 3 3 3 0 TFIIH C1-like domain Elf1 PF05129.13 CBY18041.1 - 1.2 9.3 12.3 7.2 6.7 4.9 3.5 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf_UBZ PF18439.1 CBY18041.1 - 1.8 8.2 13.5 7.9 6.2 0.7 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger PyrI_C PF02748.15 CBY18041.1 - 2.9 7.9 7.4 13 5.7 0.4 3.3 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_10 PF10058.9 CBY18041.1 - 3.1 7.6 7.1 7.7 6.3 0.2 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2_2 PF12756.7 CBY18041.1 - 4 7.8 10.0 0.22 11.9 2.5 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Evr1_Alr PF04777.13 CBY18041.1 - 4.5 7.8 10.7 2.1 8.8 2.0 3.2 1 1 2 3 3 3 0 Erv1 / Alr family zf-CHY PF05495.12 CBY18041.1 - 5.3 7.6 16.4 19 5.8 7.8 2.8 1 1 1 2 2 2 0 CHY zinc finger HypA PF01155.19 CBY18041.1 - 6 6.9 10.1 3.2 7.8 0.5 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ECH_1 PF00378.20 CBY18042.1 - 4.8e-32 111.2 0.0 6.5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY18042.1 - 2.5e-12 46.9 0.0 3.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MA3 PF02847.17 CBY18043.1 - 1e-21 77.0 1.3 2.6e-21 75.7 1.3 1.7 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CBY18043.1 - 1.7e-14 53.9 1.5 4.1e-14 52.7 1.5 1.7 1 0 0 1 1 1 1 MIF4G domain Cnd1 PF12717.7 CBY18043.1 - 0.0092 16.0 0.1 0.018 15.1 0.1 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 PK PF00224.21 CBY18044.1 - 1.7e-158 527.1 7.3 2.1e-158 526.7 7.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CBY18044.1 - 1.8e-31 108.8 0.0 5.2e-31 107.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 CBY18044.1 - 0.00075 18.6 0.1 0.00075 18.6 0.1 2.4 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain HpcH_HpaI PF03328.14 CBY18044.1 - 0.075 12.2 2.1 0.14 11.3 0.2 2.3 3 0 0 3 3 3 0 HpcH/HpaI aldolase/citrate lyase family eIF2A PF08662.11 CBY18045.1 - 6.5e-62 208.9 0.1 4.4e-61 206.2 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 CBY18045.1 - 0.08 10.9 0.0 1.2 7.0 0.0 2.3 2 1 1 3 3 3 0 IKI3 family PRELI PF04707.14 CBY18047.1 - 5.3e-31 107.6 0.3 9.1e-31 106.8 0.3 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 CBY18047.1 - 1.1e-19 70.7 0.0 2.1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBY18047.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain TSP_3 PF02412.18 CBY18047.1 - 0.16 11.7 1.3 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Thrombospondin type 3 repeat PX PF00787.24 CBY18048.1 - 9.2e-17 61.1 0.0 1.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 PX domain PDZ PF00595.24 CBY18048.1 - 2.1e-13 50.4 1.1 3.9e-13 49.5 1.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY18048.1 - 8.1e-13 48.0 0.6 1.8e-12 46.9 0.6 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY18048.1 - 1.6e-05 25.2 0.0 0.0005 20.3 0.0 2.7 3 0 0 3 3 3 1 PDZ domain Ank_4 PF13637.6 CBY18049.1 - 0.014 16.0 0.0 1 10.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PTPLA PF04387.14 CBY18050.1 - 1.2e-35 122.7 1.2 1.9e-35 122.0 1.2 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Connexin PF00029.19 CBY18050.1 - 0.036 13.8 2.9 1.9 8.2 0.5 2.2 2 0 0 2 2 2 0 Connexin HOOK PF05622.12 CBY18051.1 - 4e-196 653.3 76.2 7.5e-196 652.4 76.2 1.4 1 1 0 1 1 1 1 HOOK protein BLM10_mid PF16507.5 CBY18052.1 - 1.9e-59 201.7 1.9 1.5e-31 109.6 0.3 2.5 1 1 1 2 2 2 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 CBY18052.1 - 4.9e-28 96.9 0.3 4.2e-27 93.9 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Sec23_helical PF04815.15 CBY18052.1 - 0.023 14.5 0.4 0.29 11.0 0.0 3.0 2 0 0 2 2 2 0 Sec23/Sec24 helical domain HEAT PF02985.22 CBY18052.1 - 0.023 14.9 0.0 1.2 9.6 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 CBY18052.1 - 0.046 14.1 0.6 1 9.8 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats Codanin-1_C PF15296.6 CBY18053.1 - 1.4e-22 80.0 0.2 1.4e-22 80.0 0.2 3.2 3 0 0 3 3 3 1 Codanin-1 C-terminus FAM216B PF15107.6 CBY18053.1 - 2.3e-05 24.2 0.2 0.41 10.5 0.0 2.7 2 0 0 2 2 2 2 FAM216B protein family DUF4488 PF14869.6 CBY18053.1 - 0.00049 20.0 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4488) UPF1_Zn_bind PF09416.10 CBY18053.1 - 0.0048 16.9 0.2 5.1 7.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase (UPF2 interacting domain) EMA PF02488.15 CBY18053.1 - 0.012 15.3 0.9 4.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Merozoite Antigen DUF3310 PF11753.8 CBY18053.1 - 0.049 13.8 0.0 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) MAM1 PF10434.9 CBY18053.1 - 1.6 8.3 7.5 12 5.4 0.9 2.7 2 0 0 2 2 2 0 Monopolin complex protein MAM1 HEPN_Cthe2314 PF18730.1 CBY18053.1 - 5.7 7.0 8.8 19 5.2 1.2 2.6 2 0 0 2 2 2 0 Cthe_2314-like HEPN O-FucT PF10250.9 CBY18054.1 - 1.6e-39 136.6 0.0 3.1e-39 135.6 0.0 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase FGF-BP1 PF06473.12 CBY18054.1 - 0.22 11.3 0.0 0.34 10.7 0.0 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) LSM PF01423.22 CBY18055.1 - 5.2e-14 51.7 0.0 6.5e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain Tail_tube PF10618.9 CBY18055.1 - 0.035 14.0 0.2 4.3 7.2 0.1 2.2 1 1 1 2 2 2 0 Phage tail tube protein Rib_5-P_isom_A PF06026.14 CBY18056.1 - 1.6e-63 213.4 0.0 1.9e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CBY18056.1 - 0.0062 16.5 0.1 0.39 10.6 0.0 2.3 1 1 1 2 2 2 2 DeoR C terminal sensor domain Hint PF01079.20 CBY18058.1 - 2.2e-08 33.9 0.0 5.3e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Hint module Intein_splicing PF14890.6 CBY18058.1 - 1.3e-06 28.4 0.4 2.2e-06 27.6 0.3 1.6 1 1 0 1 1 1 1 Intein splicing domain PT-HINT PF07591.11 CBY18058.1 - 0.0001 22.5 0.1 0.00025 21.3 0.1 1.6 1 0 0 1 1 1 1 Pretoxin HINT domain EF-hand_7 PF13499.6 CBY18058.1 - 0.044 14.2 2.4 0.044 14.2 2.4 2.0 2 0 0 2 2 2 0 EF-hand domain pair Endotoxin_C PF03944.14 CBY18058.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 delta endotoxin Kinesin PF00225.23 CBY18060.1 - 1.9e-103 345.9 3.5 2.5e-103 345.5 3.5 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY18060.1 - 2.1e-38 131.6 2.7 2.5e-38 131.4 1.1 1.9 2 0 0 2 2 2 1 Microtubule binding YafQ_toxin PF15738.5 CBY18060.1 - 0.37 11.2 1.9 9.6 6.6 0.3 2.4 2 0 0 2 2 2 0 Bacterial toxin of type II toxin-antitoxin system, YafQ SlyX PF04102.12 CBY18061.1 - 0.01 16.5 4.0 0.01 16.5 4.0 8.4 6 2 3 9 9 9 2 SlyX ApoO PF09769.9 CBY18061.1 - 0.99 9.4 11.0 3.1 7.8 0.0 4.1 2 2 3 5 5 5 0 Apolipoprotein O Flagellin_C PF00700.21 CBY18061.1 - 9.5 6.7 18.0 1.4 9.3 0.2 5.5 5 2 0 5 5 5 0 Bacterial flagellin C-terminal helical region DUF4791 PF16039.5 CBY18062.1 - 0.0017 17.9 1.3 0.14 11.7 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4791) DUF5453 PF17534.2 CBY18062.1 - 0.049 13.6 2.8 0.057 13.4 0.6 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5453) DUF5527 PF17665.1 CBY18062.1 - 1.1 8.8 3.1 0.37 10.3 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5527) zf-RING_5 PF14634.6 CBY18064.1 - 2e-07 30.9 12.8 2e-07 30.9 12.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY18064.1 - 3.9e-07 30.3 13.2 3.9e-07 30.3 13.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY18064.1 - 7.7e-07 28.9 11.4 7.7e-07 28.9 11.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY18064.1 - 3.2e-05 23.7 11.2 3.2e-05 23.7 11.2 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY18064.1 - 9.5e-05 22.2 10.1 0.00024 20.9 10.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY18064.1 - 0.00055 19.7 13.0 0.00055 19.7 13.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY18064.1 - 0.00065 19.5 11.3 0.0011 18.7 11.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CBY18064.1 - 0.0007 19.6 15.3 0.0048 16.9 6.2 2.7 3 0 0 3 3 3 2 RING-type zinc-finger DUF2256 PF10013.9 CBY18064.1 - 0.012 15.7 0.2 0.012 15.7 0.2 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Rad50_zn_hook PF04423.14 CBY18064.1 - 0.013 15.4 4.5 0.015 15.1 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif PspA_IM30 PF04012.12 CBY18064.1 - 0.04 13.5 3.4 0.085 12.4 3.5 1.5 1 1 0 1 1 1 0 PspA/IM30 family Rtf2 PF04641.12 CBY18064.1 - 0.079 12.3 8.7 0.042 13.2 6.6 1.6 1 1 0 1 1 1 0 Rtf2 RING-finger Exonuc_VII_S PF02609.16 CBY18064.1 - 0.08 13.0 1.2 0.16 12.0 1.2 1.5 1 0 0 1 1 1 0 Exonuclease VII small subunit INPP5B_PH PF16776.5 CBY18064.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain DUF3695 PF12494.8 CBY18064.1 - 0.19 11.6 1.1 17 5.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3695) cNMP_binding PF00027.29 CBY18065.1 - 8.7e-12 45.0 0.0 3.7e-07 30.1 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CBY18065.1 - 0.048 13.4 0.3 0.29 10.9 0.0 2.4 3 0 0 3 3 3 0 Cupin domain G-alpha PF00503.20 CBY18066.1 - 7e-116 387.2 5.9 8.2e-116 387.0 5.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY18066.1 - 7.7e-18 64.5 1.4 2.2e-11 43.5 0.3 3.3 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CBY18066.1 - 9.9e-05 22.5 0.9 0.55 10.5 0.1 3.4 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CBY18066.1 - 0.035 13.5 0.1 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 CBY18066.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CBY18066.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pep3_Vps18 PF05131.14 CBY18067.1 - 1.5e-30 106.0 0.0 4e-30 104.6 0.0 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CBY18067.1 - 1.3e-05 25.1 4.6 0.034 14.0 0.0 3.6 4 1 1 5 5 5 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CBY18067.1 - 2e-05 25.0 0.8 0.00012 22.5 0.8 2.4 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 CBY18067.1 - 0.0044 16.6 4.3 0.0048 16.5 2.3 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Tup_N PF08581.10 CBY18067.1 - 0.051 13.9 0.9 0.44 10.9 0.3 2.5 2 0 0 2 2 2 0 Tup N-terminal PspA_IM30 PF04012.12 CBY18067.1 - 0.092 12.3 4.5 1.4 8.5 0.7 2.5 2 0 0 2 2 2 0 PspA/IM30 family UPF0184 PF03670.13 CBY18067.1 - 0.1 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DivIC PF04977.15 CBY18067.1 - 0.14 12.0 0.4 0.34 10.7 0.4 1.6 1 0 0 1 1 1 0 Septum formation initiator CDT1_C PF16679.5 CBY18067.1 - 0.21 12.1 2.3 2 8.9 0.0 3.0 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain THOC7 PF05615.13 CBY18067.1 - 0.33 11.2 2.2 0.57 10.5 0.0 2.4 3 0 0 3 3 3 0 Tho complex subunit 7 zf-RING_5 PF14634.6 CBY18067.1 - 10 6.2 9.8 68 3.5 9.8 2.4 1 1 0 1 1 1 0 zinc-RING finger domain Chromo PF00385.24 CBY18069.1 - 1.8e-17 62.9 2.7 4.7e-17 61.6 2.7 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-C2H2 PF00096.26 CBY18069.1 - 0.0011 19.2 31.9 0.12 12.9 0.1 5.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 CBY18069.1 - 0.0037 17.1 1.7 2.6 8.0 0.2 3.0 2 0 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 CBY18069.1 - 0.0082 16.9 36.3 0.098 13.5 0.1 5.8 6 0 0 6 6 5 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY18069.1 - 0.036 13.8 0.5 0.036 13.8 0.5 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Tudor-knot PF11717.8 CBY18069.1 - 0.048 13.5 0.1 0.17 11.8 0.1 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Ndr PF03096.14 CBY18069.1 - 0.057 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Ndr family zf-met PF12874.7 CBY18069.1 - 0.083 13.3 3.1 2.5 8.6 0.4 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Regnase_1_C PF18561.1 CBY18069.1 - 0.11 12.3 0.1 25 4.7 0.0 2.7 2 0 0 2 2 2 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Peptidase_U57 PF05582.12 CBY18069.1 - 0.13 11.5 2.0 0.33 10.2 2.0 1.6 1 0 0 1 1 1 0 YabG peptidase U57 zf-C2H2_jaz PF12171.8 CBY18069.1 - 0.17 12.2 12.4 1.2 9.6 1.5 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY18069.1 - 0.17 11.9 12.7 2.4 8.3 1.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBY18069.1 - 6.9 6.4 12.2 2.4 7.8 0.7 3.6 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_15 PF17032.5 CBY18069.1 - 9.4 7.1 10.1 10 7.0 0.2 2.9 1 1 1 2 2 2 0 zinc-ribbon family Pkinase PF00069.25 CBY18070.1 - 1.8e-73 247.2 0.0 2.5e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18070.1 - 1.1e-48 165.9 0.0 1.5e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CBY18070.1 - 5.2e-17 61.9 0.6 2.1e-16 60.0 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CBY18070.1 - 1.2e-05 24.3 0.0 2.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY18070.1 - 2.4e-05 23.8 0.0 0.00037 19.9 0.0 2.4 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 CBY18070.1 - 0.1 12.5 0.0 1.7 8.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY18070.1 - 0.21 10.5 0.5 0.54 9.2 0.5 1.7 1 1 0 1 1 1 0 Haspin like kinase domain DBR1 PF05011.13 CBY18071.1 - 0.037 14.4 0.6 0.058 13.8 0.6 1.3 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Tetraspanin PF00335.20 CBY18071.1 - 0.05 13.3 0.2 0.068 12.9 0.2 1.2 1 0 0 1 1 1 0 Tetraspanin family ABC_membrane_3 PF13748.6 CBY18071.1 - 0.051 12.8 0.3 0.071 12.3 0.3 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region LPP20 PF02169.16 CBY18071.1 - 1.3 9.4 4.1 4.2 7.8 2.2 2.4 3 0 0 3 3 3 0 LPP20 lipoprotein TMEMspv1-c74-12 PF11044.8 CBY18071.1 - 7.6 6.6 7.5 1.4 9.0 1.1 2.4 2 1 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DnaJ_C PF01556.18 CBY18072.1 - 2e-34 118.8 1.9 2.6e-34 118.4 1.9 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBY18072.1 - 3.4e-26 91.2 1.7 5e-26 90.6 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain DUF2151 PF10221.9 CBY18073.1 - 1.2e-80 272.0 1.3 1.2e-78 265.5 1.3 2.2 1 1 0 1 1 1 1 Cell cycle and development regulator DUF1542 PF07564.11 CBY18073.1 - 0.15 12.2 6.1 2 8.6 0.2 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) Aminotran_1_2 PF00155.21 CBY18074.1 - 1.4e-56 192.2 0.0 1.7e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBY18074.1 - 1.8e-05 24.1 0.1 2.9e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 CBY18074.1 - 0.015 14.1 0.1 0.036 12.8 0.1 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 CBY18074.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CHASE3 PF05227.13 CBY18074.1 - 0.16 11.9 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 CHASE3 domain Mito_carr PF00153.27 CBY18075.1 - 1.5e-44 149.9 0.8 1.2e-16 60.4 0.0 3.2 1 1 2 3 3 3 3 Mitochondrial carrier protein Tail_VII PF17091.5 CBY18075.1 - 0.058 13.3 2.5 6.2 6.8 0.1 2.6 2 0 0 2 2 2 0 Inovirus G7P protein Exo_endo_phos PF03372.23 CBY18077.1 - 1.3e-06 28.1 0.0 5e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pox_A22 PF04848.13 CBY18077.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A22 protein DrrA_P4M PF14860.6 CBY18077.1 - 0.13 12.1 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain LIM PF00412.22 CBY18078.1 - 1.8e-22 79.3 29.0 9.5e-13 48.2 11.0 2.1 2 0 0 2 2 2 2 LIM domain DUF4428 PF14471.6 CBY18078.1 - 0.026 14.4 13.9 0.36 10.8 3.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Gelsolin PF00626.22 CBY18079.1 - 8.7e-06 25.6 5.8 0.61 10.0 0.0 5.5 6 1 1 7 7 7 3 Gelsolin repeat Fic_N PF13784.6 CBY18080.1 - 0.064 13.3 5.1 0.23 11.5 0.3 3.2 2 0 0 2 2 2 0 Fic/DOC family N-terminal RICTOR_phospho PF14665.6 CBY18081.1 - 0.044 14.1 2.2 0.074 13.4 2.2 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Rhodanese PF00581.20 CBY18082.1 - 3.1e-07 30.9 0.0 5.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain HORMA PF02301.18 CBY18085.1 - 2.1e-20 73.2 0.0 2.8e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 HORMA domain IPTL-CTERM PF18203.1 CBY18086.1 - 0.021 14.7 0.5 0.057 13.3 0.5 1.7 1 0 0 1 1 1 0 IPTL-CTERM motif fn3 PF00041.21 CBY18087.1 - 9.2e-78 256.7 41.6 2.1e-10 40.8 0.1 17.1 18 0 0 18 18 18 13 Fibronectin type III domain fn2 PF00040.19 CBY18087.1 - 2e-14 53.5 8.6 2e-14 53.5 8.6 4.5 4 0 0 4 4 4 2 Fibronectin type II domain Ig_3 PF13927.6 CBY18087.1 - 0.004 17.7 2.0 0.23 12.1 0.0 5.0 5 0 0 5 5 5 1 Immunoglobulin domain GH115_C PF17829.1 CBY18087.1 - 0.25 11.2 1.8 0.91 9.3 0.2 2.6 3 0 0 3 3 3 0 Gylcosyl hydrolase family 115 C-terminal domain fn1 PF00039.18 CBY18087.1 - 0.53 10.5 34.8 0.025 14.7 2.2 4.5 5 0 0 5 5 5 0 Fibronectin type I domain I-set PF07679.16 CBY18087.1 - 0.56 10.3 8.1 0.44 10.6 0.1 4.7 6 0 0 6 6 6 0 Immunoglobulin I-set domain ASH PF15780.5 CBY18087.1 - 2.1 8.6 4.3 23 5.3 0.0 4.4 5 0 0 5 5 5 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SIX1_SD PF16878.5 CBY18089.1 - 2.8e-43 147.0 0.1 1.3e-42 144.8 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CBY18089.1 - 2.5e-13 49.6 1.4 5.4e-13 48.6 1.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY18089.1 - 4.9e-11 42.3 1.4 1.3e-10 40.9 1.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain Phage_mat-A PF03863.13 CBY18089.1 - 0.0077 15.2 0.1 0.011 14.7 0.1 1.1 1 0 0 1 1 1 1 Phage maturation protein Homez PF11569.8 CBY18089.1 - 0.074 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 CBY18089.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix LRR_3 PF07725.12 CBY18089.1 - 0.22 11.4 1.2 0.71 9.8 0.2 2.1 2 0 0 2 2 2 0 Leucine Rich Repeat GCS PF03074.16 CBY18090.1 - 1.4e-162 541.2 0.0 1.8e-162 540.9 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 CBY18090.1 - 0.086 12.2 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) RRM_1 PF00076.22 CBY18091.1 - 1.4e-42 143.4 0.1 1.3e-19 69.8 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY18091.1 - 3.7e-05 23.8 0.4 0.12 12.5 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 CBY18091.1 - 0.014 15.4 0.0 8.4 6.5 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 DUF4570 PF15134.6 CBY18091.1 - 0.054 13.5 1.7 0.16 12.0 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Cu2_monoox_C PF03712.15 CBY18092.1 - 1.6e-20 73.2 0.0 3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain NHL PF01436.21 CBY18092.1 - 6.7e-20 70.0 1.7 2.2e-08 33.7 0.1 4.2 3 0 0 3 3 3 3 NHL repeat Cu2_monooxygen PF01082.20 CBY18092.1 - 4.4e-07 30.2 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DUF5128 PF17170.4 CBY18092.1 - 0.0037 16.5 0.3 0.0037 16.5 0.3 2.4 3 0 0 3 3 3 1 6-bladed beta-propeller Arylesterase PF01731.20 CBY18092.1 - 0.056 13.7 0.0 15 5.9 0.0 2.7 2 0 0 2 2 2 0 Arylesterase Trypsin PF00089.26 CBY18096.1 - 4.6e-08 33.1 0.2 5.2e-08 33.0 0.2 1.0 1 0 0 1 1 1 1 Trypsin Defensin_2 PF01097.18 CBY18096.1 - 0.061 13.3 0.5 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 Arthropod defensin Trypsin PF00089.26 CBY18097.1 - 3.7e-43 147.9 0.8 4.1e-43 147.7 0.8 1.0 1 0 0 1 1 1 1 Trypsin G8 PF10162.9 CBY18098.1 - 2.4e-54 182.6 0.0 1e-30 106.3 0.0 3.3 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 CBY18098.1 - 3.3e-41 139.3 40.3 1.4e-10 41.1 0.3 8.3 8 0 0 8 8 8 6 IPT/TIG domain Cupredoxin_1 PF13473.6 CBY18098.1 - 0.062 13.4 0.0 15 5.8 0.0 2.8 2 0 0 2 2 2 0 Cupredoxin-like domain DUF1732 PF08340.11 CBY18099.1 - 0.03 14.3 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Macoilin PF09726.9 CBY18099.1 - 0.043 12.4 5.3 0.054 12.1 5.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF4679 PF15728.5 CBY18099.1 - 0.048 12.7 9.6 0.054 12.5 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) JAB PF01398.21 CBY18100.1 - 6.3e-07 29.4 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Formin_GBD_N PF18382.1 CBY18100.1 - 0.066 13.7 0.0 7.2 7.1 0.0 2.9 2 0 0 2 2 2 0 Formin N-terminal GTPase-binding domain Hrs_helical PF12210.8 CBY18102.1 - 8e-35 119.3 4.5 8e-35 119.3 4.5 2.9 3 0 0 3 3 3 1 Hepatocyte growth factor-regulated tyrosine kinase substrate VHS PF00790.19 CBY18102.1 - 1.5e-30 105.9 0.0 1.5e-30 105.9 0.0 1.7 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 CBY18102.1 - 4.9e-19 68.2 8.5 1.1e-18 67.2 8.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger DUF1885 PF08968.10 CBY18102.1 - 0.08 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) DZR PF12773.7 CBY18102.1 - 1.8 8.7 9.3 2.3e+02 1.9 9.8 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_5 PF14634.6 CBY18102.1 - 2.9 7.9 13.1 8.2 6.5 13.3 1.7 1 1 0 1 1 1 0 zinc-RING finger domain EF-hand_7 PF13499.6 CBY18103.1 - 2e-17 63.4 27.7 5.7e-07 29.9 3.8 4.9 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 CBY18103.1 - 2.1e-17 61.3 32.5 0.00028 20.2 0.2 7.3 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 CBY18103.1 - 6.7e-13 47.4 22.5 0.0011 18.8 0.2 7.1 7 0 0 7 7 7 6 EF-hand domain EF-hand_5 PF13202.6 CBY18103.1 - 1.8e-11 43.0 30.2 0.00089 18.7 0.2 7.0 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.6 CBY18103.1 - 1e-06 28.4 29.1 0.039 13.8 0.3 6.4 5 2 2 7 7 7 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY18103.1 - 2.1e-05 24.8 12.9 0.092 13.1 4.4 3.5 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region CCDC32 PF14989.6 CBY18103.1 - 0.0076 16.3 0.5 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 Coiled-coil domain containing 32 EF-hand_4 PF12763.7 CBY18103.1 - 0.89 9.5 12.7 1.6 8.7 0.2 4.8 2 1 3 5 5 5 0 Cytoskeletal-regulatory complex EF hand CDP-OH_P_transf PF01066.21 CBY18104.1 - 5.2e-14 52.8 0.0 5.2e-14 52.8 0.0 3.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CYYR1 PF10873.8 CBY18104.1 - 4.8 7.6 9.7 6.1 7.3 0.4 2.4 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Epiglycanin_C PF14654.6 CBY18104.1 - 5.8 7.0 6.0 8.9 6.4 4.0 2.2 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Sec1 PF00995.23 CBY18105.1 - 2.1e-112 377.2 3.5 2.5e-112 377.0 3.5 1.1 1 0 0 1 1 1 1 Sec1 family hDGE_amylase PF14701.6 CBY18106.1 - 1.6e-115 386.8 0.0 3.3e-115 385.7 0.0 1.5 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CBY18106.1 - 6.2e-98 328.2 0.0 9.7e-98 327.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CBY18106.1 - 2.9e-44 151.6 0.1 4.9e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme Alpha-amylase PF00128.24 CBY18106.1 - 1.8e-05 24.5 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Pkinase PF00069.25 CBY18108.1 - 9.4e-57 192.4 0.0 1.7e-56 191.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18108.1 - 2.1e-27 96.0 0.0 2.9e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY18108.1 - 0.00015 21.2 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY18108.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBY18108.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATG7_N PF16420.5 CBY18110.1 - 1.5e-51 175.9 4.5 2.1e-51 175.4 4.5 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CBY18110.1 - 3.2e-44 151.1 0.0 5.5e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 CBY18110.1 - 0.0056 16.0 0.0 0.033 13.6 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CBY18110.1 - 0.008 16.2 0.9 0.053 13.6 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Sigma70_ner PF04546.13 CBY18112.1 - 0.025 14.5 0.1 0.042 13.7 0.1 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region RNA_pol_Rpc82 PF05645.13 CBY18112.1 - 0.042 13.6 1.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Radial_spoke PF04712.12 CBY18114.1 - 5.6e-187 622.6 5.5 6.7e-187 622.3 5.5 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein Rhabdo_ncap PF00945.18 CBY18114.1 - 1.4 7.8 3.4 2.5 6.9 3.4 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein FH2 PF02181.23 CBY18115.1 - 8.6e-74 248.9 1.3 1.9e-73 247.8 1.3 1.6 1 0 0 1 1 1 1 Formin Homology 2 Domain Formin_GBD_N PF18382.1 CBY18115.1 - 8.9e-39 131.9 1.5 2.3e-38 130.6 0.0 2.6 2 0 0 2 2 2 1 Formin N-terminal GTPase-binding domain Mesd PF10185.9 CBY18116.1 - 6.2e-27 94.4 0.0 8.3e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor Use1 PF09753.9 CBY18117.1 - 3.9e-17 62.8 6.2 7e-17 62.0 6.2 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Proteasome PF00227.26 CBY18118.1 - 2.8e-40 137.9 0.0 3.1e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf_Hakai PF18408.1 CBY18119.1 - 1.7e-18 66.0 4.2 1.7e-18 66.0 4.2 1.9 2 0 0 2 2 2 1 C2H2 Hakai zinc finger domain zf-C3HC4 PF00097.25 CBY18119.1 - 0.00074 19.3 9.8 0.00074 19.3 9.8 1.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY18119.1 - 0.022 14.6 12.4 0.022 14.6 12.4 2.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY18119.1 - 0.54 10.2 17.2 0.062 13.1 11.6 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY18119.1 - 1.4 9.3 16.4 0.59 10.5 13.8 1.8 1 1 1 2 2 2 0 Ring finger domain zinc-ribbons_6 PF07191.12 CBY18119.1 - 2.1 8.4 12.9 3.6 7.7 12.9 1.4 1 0 0 1 1 1 0 zinc-ribbons SNF2_N PF00176.23 CBY18120.1 - 3e-74 249.9 2.0 9e-74 248.3 2.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CBY18120.1 - 6.8e-38 129.2 2.1 4.7e-37 126.5 2.1 2.6 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 CBY18120.1 - 9.7e-26 90.7 5.8 9.7e-26 90.7 5.8 3.8 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 CBY18120.1 - 3.7e-20 72.3 0.2 1.5e-18 67.2 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY18120.1 - 6.4e-11 42.5 0.3 6.9e-10 39.2 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBY18120.1 - 1.1e-07 31.8 0.2 3.8e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 CBY18120.1 - 0.012 15.8 0.0 2.2 8.6 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain RhoGAP PF00620.27 CBY18121.1 - 2.4e-16 59.9 0.0 3.1e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF349 PF03993.12 CBY18122.1 - 0.054 13.8 5.1 0.4 11.0 0.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) RPE65 PF03055.15 CBY18123.1 - 3e-84 283.8 0.0 3.7e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Ion_trans_2 PF07885.16 CBY18124.1 - 2.9e-09 36.8 6.5 2.9e-09 36.8 6.5 2.2 2 1 0 2 2 2 1 Ion channel SK_channel PF03530.14 CBY18124.1 - 0.00081 19.4 2.5 0.00081 19.4 2.5 2.2 2 1 0 2 2 2 1 Calcium-activated SK potassium channel DUF2985 PF11204.8 CBY18124.1 - 0.084 13.0 2.6 0.11 12.6 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) DUF1951 PF09188.10 CBY18124.1 - 7.3 6.6 7.2 0.97 9.4 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1951) 7tm_1 PF00001.21 CBY18125.1 - 2.9e-47 161.2 18.9 4.7e-47 160.5 18.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Kringle PF00051.18 CBY18125.1 - 4.4e-22 78.2 1.1 1.2e-21 76.7 1.1 1.9 1 0 0 1 1 1 1 Kringle domain 7TM_GPCR_Srx PF10328.9 CBY18125.1 - 3.8e-12 46.4 5.3 3.8e-12 46.4 5.3 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CBY18125.1 - 4.5e-10 39.4 18.5 9.1e-09 35.1 18.5 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CBY18125.1 - 1.3e-06 28.4 12.5 3.1e-06 27.2 12.5 1.5 1 1 0 1 1 1 1 Olfactory receptor DUF1146 PF06612.11 CBY18125.1 - 0.12 12.5 0.5 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) 7TM_GPCR_Srd PF10317.9 CBY18125.1 - 0.7 9.0 23.6 2.8 7.1 3.2 3.4 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF4134 PF13572.6 CBY18125.1 - 2 8.8 6.5 0.45 10.8 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) Git3 PF11710.8 CBY18125.1 - 3.3 7.4 9.9 0.15 11.9 4.1 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Mucin PF01456.17 CBY18126.1 - 0.16 12.0 27.8 0.27 11.2 27.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PRCC PF10253.9 CBY18126.1 - 0.9 10.3 6.8 0.31 11.8 4.2 1.5 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting NUC153 PF08159.12 CBY18127.1 - 1.4e-10 40.8 0.3 2.6e-10 39.9 0.3 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 CBY18127.1 - 5.7e-07 30.1 0.0 0.029 15.2 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Acetyltransf_1 PF00583.25 CBY18128.1 - 6.2e-17 61.9 0.0 8.7e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY18128.1 - 3.4e-10 39.9 0.0 4.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY18128.1 - 1.1e-08 35.3 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY18128.1 - 1.5e-06 28.0 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CBY18128.1 - 0.00013 22.0 0.1 0.00023 21.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CBY18128.1 - 0.00082 20.1 0.1 0.0031 18.2 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 CBY18128.1 - 0.019 14.9 0.1 0.035 14.1 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 CBY18128.1 - 0.053 13.0 0.1 0.083 12.4 0.1 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase 3HCDH_N PF02737.18 CBY18129.1 - 1e-58 198.2 0.6 2.5e-58 196.9 0.9 1.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CBY18129.1 - 1.5e-33 115.3 0.0 9.4e-33 112.7 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CBY18129.1 - 1.4e-05 24.7 0.8 3.3e-05 23.6 0.6 1.7 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CBY18129.1 - 0.00084 18.7 1.4 0.0014 17.9 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 CBY18129.1 - 0.00086 19.5 2.8 0.0022 18.2 2.8 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 CBY18129.1 - 0.0046 17.0 1.4 0.014 15.4 1.3 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short_C2 PF13561.6 CBY18129.1 - 0.0064 16.1 0.5 0.011 15.3 0.5 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_2 PF07992.14 CBY18129.1 - 0.0091 15.3 0.2 0.015 14.5 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY18129.1 - 0.014 14.5 0.9 0.016 14.3 0.9 1.1 1 0 0 1 1 1 0 FAD binding domain DUF1188 PF06690.11 CBY18129.1 - 0.026 14.1 0.1 0.051 13.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1188) F420_oxidored PF03807.17 CBY18129.1 - 0.044 14.4 2.8 0.15 12.6 2.7 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DXP_synthase_N PF13292.6 CBY18129.1 - 0.11 11.7 0.9 0.21 10.8 0.9 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase NAD_binding_8 PF13450.6 CBY18129.1 - 0.23 11.7 0.7 0.45 10.8 0.7 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TFIIS_C PF01096.18 CBY18130.1 - 4.3e-09 36.1 2.9 5.5e-09 35.7 2.9 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) zf-Dof PF02701.15 CBY18130.1 - 0.0019 18.3 6.3 0.0029 17.7 6.3 1.3 1 0 0 1 1 1 1 Dof domain, zinc finger Zn_Tnp_IS1 PF03811.13 CBY18130.1 - 0.0099 15.6 1.3 0.025 14.3 1.3 1.7 1 1 0 1 1 1 1 InsA N-terminal domain PhnA_Zn_Ribbon PF08274.12 CBY18130.1 - 0.042 13.8 0.6 0.097 12.6 0.6 1.6 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 CBY18130.1 - 0.05 13.6 2.8 0.081 12.9 2.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Terminase_GpA PF05876.12 CBY18130.1 - 0.17 10.4 2.4 0.2 10.2 2.4 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) RRM_5 PF13893.6 CBY18131.1 - 2.9e-40 136.7 0.2 6.1e-34 116.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBY18131.1 - 1.2e-13 50.7 0.1 0.0004 20.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CBY18131.1 - 1.7e-07 31.4 0.0 3.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 CBY18131.1 - 2.3e-07 30.6 0.2 0.045 13.6 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif RL PF17797.1 CBY18131.1 - 0.009 15.9 0.0 3.9 7.5 0.0 2.8 3 0 0 3 3 3 2 RL domain RTC PF01137.21 CBY18132.1 - 3.1e-50 170.4 0.0 3.6e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CBY18132.1 - 8.7e-32 109.7 0.1 1.4e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Sec16_C PF12931.7 CBY18133.1 - 3.7e-08 33.4 0.2 8.9e-07 28.8 0.2 2.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 CBY18133.1 - 1.8e-05 24.9 0.1 0.15 12.3 0.0 3.6 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY18133.1 - 0.00032 21.4 0.0 4.8 8.2 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat SRA1 PF07304.11 CBY18133.1 - 0.00064 19.5 0.0 0.0027 17.5 0.0 2.1 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) EMC3_TMCO1 PF01956.16 CBY18134.1 - 2.4e-30 105.5 2.0 3.1e-30 105.2 2.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF4199 PF13858.6 CBY18134.1 - 1.7e-05 25.3 1.3 1.7e-05 25.3 1.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) PHM7_cyt PF14703.6 CBY18134.1 - 0.009 16.3 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Occludin_ELL PF07303.13 CBY18134.1 - 0.041 14.6 1.8 0.061 14.1 1.8 1.2 1 0 0 1 1 1 0 Occludin homology domain DUF3847 PF12958.7 CBY18134.1 - 0.047 13.8 1.5 0.07 13.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) BLOC1_2 PF10046.9 CBY18134.1 - 0.15 12.4 3.3 0.23 11.8 3.3 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pro_isomerase PF00160.21 CBY18135.1 - 1.2e-47 162.2 0.0 1.4e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_5 PF13857.6 CBY18136.1 - 5.2e-17 61.7 0.0 3.7e-06 27.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY18136.1 - 5.3e-16 59.0 0.1 2.1e-09 37.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY18136.1 - 5.1e-14 52.4 0.0 4.8e-06 27.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY18136.1 - 4.9e-12 45.7 0.1 0.004 17.6 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CBY18136.1 - 1.3e-11 43.7 0.0 0.062 13.9 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat BRCT_3 PF18428.1 CBY18136.1 - 0.0081 16.2 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NFACT-C PF11923.8 CBY18136.1 - 0.046 13.6 0.8 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 NFACT protein C-terminal domain DEAD PF00270.29 CBY18137.1 - 1.9e-51 174.3 0.1 3.2e-51 173.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY18137.1 - 8.1e-30 103.4 0.2 7.7e-29 100.3 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CBY18137.1 - 0.0053 17.1 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain Helicase_C_2 PF13307.6 CBY18137.1 - 0.077 13.2 0.0 0.37 10.9 0.0 2.1 1 1 1 2 2 2 0 Helicase C-terminal domain RFX_DNA_binding PF02257.15 CBY18139.1 - 0.027 15.1 0.0 0.087 13.5 0.0 2.0 1 0 0 1 1 1 0 RFX DNA-binding domain Astacin PF01400.24 CBY18140.1 - 2.4e-56 190.4 0.0 3.8e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 CBY18140.1 - 7.8e-07 29.1 0.4 2.9e-06 27.3 0.1 2.2 2 1 0 2 2 2 1 MAM domain, meprin/A5/mu Pkinase PF00069.25 CBY18142.1 - 5.4e-69 232.5 0.0 6.2e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18142.1 - 7.1e-34 117.2 0.0 8.9e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY18142.1 - 0.0043 16.4 0.1 0.014 14.8 0.1 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CBY18142.1 - 0.021 14.7 0.0 0.13 12.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ints3 PF10189.9 CBY18143.1 - 5.3e-80 267.9 1.8 5.3e-80 267.9 1.8 1.8 2 0 0 2 2 2 1 Integrator complex subunit 3 Kelch_1 PF01344.25 CBY18144.1 - 2e-48 161.7 13.3 4.4e-13 48.6 0.0 6.9 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBY18144.1 - 1.6e-34 117.0 0.7 7.4e-06 26.1 0.0 6.5 3 1 3 6 6 6 5 Kelch motif BTB PF00651.31 CBY18144.1 - 1e-29 103.0 1.4 3.3e-29 101.4 1.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 CBY18144.1 - 2.1e-26 92.0 0.6 6.3e-26 90.5 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CBY18144.1 - 1.1e-21 75.9 7.5 2.1e-05 24.3 0.0 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 CBY18144.1 - 9.2e-21 73.6 4.6 0.00047 20.4 0.1 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY18144.1 - 7.5e-17 61.1 4.8 0.0088 16.0 0.0 5.4 3 2 2 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY18144.1 - 2.6e-15 56.0 9.5 0.0058 16.6 0.0 6.3 6 0 0 6 6 6 5 Kelch motif PQQ_3 PF13570.6 CBY18144.1 - 0.00013 22.4 1.0 0.23 12.0 0.0 3.8 5 0 0 5 5 5 1 PQQ-like domain DUF3342 PF11822.8 CBY18144.1 - 0.02 15.1 0.2 0.081 13.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) HU-CCDC81_euk_1 PF14908.6 CBY18144.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 Peptidase_M17 PF00883.21 CBY18145.1 - 8.6e-92 307.7 0.2 1.2e-91 307.2 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain zf-C3HC4_2 PF13923.6 CBY18145.1 - 4.9e-09 35.9 6.3 1.5e-08 34.4 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY18145.1 - 1.5e-08 34.3 5.9 4.5e-08 32.8 5.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Pdase_M17_N2 PF18295.1 CBY18145.1 - 1.7e-06 28.3 0.5 1.9e-05 24.9 0.0 2.6 2 1 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 zf-RING_2 PF13639.6 CBY18145.1 - 5.8e-06 26.5 6.5 5.8e-06 26.5 6.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY18145.1 - 1.3e-05 25.0 5.5 1.3e-05 25.0 5.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY18145.1 - 4.2e-05 23.6 6.9 0.00014 22.0 6.9 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TerY_C PF15616.6 CBY18145.1 - 0.0012 19.0 0.7 0.0025 17.9 0.7 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_UBOX PF13445.6 CBY18145.1 - 0.005 16.8 9.0 0.016 15.2 9.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY18145.1 - 0.0065 16.4 9.6 0.028 14.4 9.7 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 CBY18145.1 - 0.0076 16.1 1.5 0.0076 16.1 1.5 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 CBY18145.1 - 0.033 14.1 6.0 0.023 14.5 3.8 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CBY18145.1 - 0.058 13.5 5.5 0.14 12.3 5.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 CBY18145.1 - 0.17 12.2 11.1 0.76 10.1 11.1 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CBY18145.1 - 0.31 10.9 16.1 0.098 12.5 10.7 2.7 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY18145.1 - 3.9 7.3 6.0 9.8 6.1 6.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CK_II_beta PF01214.18 CBY18146.1 - 1.9e-84 282.0 0.1 2.2e-84 281.8 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 CBY18146.1 - 0.026 14.6 0.2 0.045 13.8 0.2 1.5 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases CK_II_beta PF01214.18 CBY18147.1 - 2.9e-35 121.7 0.0 3.8e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Thioredoxin PF00085.20 CBY18148.1 - 1.5e-20 73.0 0.0 2.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.20 CBY18148.1 - 4.1e-11 42.9 0.0 6.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 CBY18148.1 - 4.2e-05 24.0 0.0 0.00026 21.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBY18148.1 - 0.0074 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBY18148.1 - 0.017 15.4 0.0 0.058 13.7 0.0 1.8 2 1 1 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.21 CBY18148.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 CBY18148.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Phosducin PF02114.16 CBY18148.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosducin Redoxin PF08534.10 CBY18148.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Redoxin Pkinase_Tyr PF07714.17 CBY18150.1 - 3.2e-05 23.4 0.0 3.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY18151.1 - 3.8e-60 203.5 0.4 5.1e-60 203.1 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18151.1 - 3.5e-39 134.6 0.1 4.7e-39 134.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBY18151.1 - 7.8e-05 22.4 0.4 0.26 10.9 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CBY18151.1 - 7.9e-05 22.3 0.3 0.00012 21.7 0.3 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 CBY18151.1 - 0.00019 20.5 0.3 0.00035 19.6 0.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY18151.1 - 0.0012 17.7 0.0 0.0049 15.7 0.0 1.5 1 1 1 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CBY18151.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY18151.1 - 0.015 14.9 0.1 0.048 13.2 0.0 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 CBY18151.1 - 0.2 11.5 0.1 0.39 10.6 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family TBP PF00352.21 CBY18152.1 - 1.6e-35 120.9 0.0 3e-20 72.0 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CBY18152.1 - 0.036 14.2 0.1 0.093 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) E2F_TDP PF02319.20 CBY18153.1 - 9.4e-28 96.1 2.2 3.6e-15 55.8 0.0 3.1 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain DZR PF12773.7 CBY18153.1 - 0.089 12.8 0.7 0.24 11.5 0.7 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CBY18153.1 - 0.13 12.1 1.8 0.25 11.2 1.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TrmB PF01978.19 CBY18153.1 - 0.17 11.8 0.1 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB zf-RING_4 PF14570.6 CBY18153.1 - 1.3 8.9 2.9 2.5 8.0 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 CBY18154.1 - 3.7e-61 206.8 0.0 3.7e-61 206.8 0.0 2.6 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18154.1 - 6e-41 140.4 0.0 6e-41 140.4 0.0 2.7 3 1 0 3 3 3 1 Protein tyrosine kinase Suppressor_P21 PF11479.8 CBY18154.1 - 0.02 15.1 0.2 0.46 10.7 0.0 2.6 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain APH PF01636.23 CBY18154.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.6 4 0 0 4 4 4 0 Phosphotransferase enzyme family HRG PF16954.5 CBY18155.1 - 0.039 14.3 0.1 0.039 14.3 0.1 3.2 4 0 0 4 4 4 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene TauE PF01925.19 CBY18155.1 - 0.56 9.8 8.0 1.4 8.5 8.0 1.7 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE TMEM43 PF07787.12 CBY18155.1 - 4.2 6.7 5.3 6.7 6.0 5.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 DUF659 PF04937.15 CBY18156.1 - 0.017 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) ORC4_C PF14629.6 CBY18158.1 - 3.6e-15 55.9 0.6 5.3e-15 55.4 0.6 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 CBY18158.1 - 7.3e-05 23.2 0.1 0.00014 22.2 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY18158.1 - 0.00041 20.8 0.1 0.00093 19.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 CBY18158.1 - 0.00052 19.2 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CBY18158.1 - 0.0021 18.1 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY18158.1 - 0.0021 18.4 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_8 PF12780.7 CBY18158.1 - 0.0024 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_22 PF13401.6 CBY18158.1 - 0.0027 18.0 0.0 0.0067 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CBY18158.1 - 0.0043 16.6 1.0 0.16 11.4 0.1 2.7 1 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 CBY18158.1 - 0.0052 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 CBY18158.1 - 0.013 16.0 0.2 0.044 14.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 CBY18158.1 - 0.021 14.6 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 CBY18158.1 - 0.025 13.7 0.1 0.042 12.9 0.1 1.4 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 CBY18158.1 - 0.031 13.7 0.0 0.089 12.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 CBY18158.1 - 0.032 13.4 0.1 0.046 12.9 0.1 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 CBY18158.1 - 0.05 13.6 0.1 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CBY18158.1 - 0.053 12.8 0.6 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin TniB PF05621.11 CBY18158.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Viral_helicase1 PF01443.18 CBY18158.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CBY18158.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 CBY18158.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 CBY18158.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.17 CBY18158.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CBY18158.1 - 0.16 11.9 0.1 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase FtsJ PF01728.19 CBY18160.1 - 2.8e-20 73.1 0.0 4.3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3231 PF11553.8 CBY18161.1 - 0.02 14.5 0.8 0.039 13.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) YAF2_RYBP PF17219.3 CBY18161.1 - 0.035 13.7 0.3 0.071 12.7 0.3 1.5 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 CBY18162.1 - 9.8e-08 31.2 2.3 1.4e-07 30.7 2.3 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-HIT PF04438.16 CBY18162.1 - 0.032 14.1 2.4 0.052 13.4 2.4 1.2 1 0 0 1 1 1 0 HIT zinc finger HEM4 PF02602.15 CBY18162.1 - 0.054 12.8 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD DUF5607 PF18355.1 CBY18162.1 - 0.12 12.9 0.4 0.19 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) Vps36-NZF-N PF16988.5 CBY18162.1 - 0.13 11.7 4.3 0.3 10.5 4.3 1.6 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 CBY18162.1 - 0.77 9.9 4.7 0.26 11.4 0.7 2.0 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger C1_2 PF03107.16 CBY18162.1 - 4.6 7.6 8.4 0.12 12.7 2.2 1.6 2 0 0 2 2 2 0 C1 domain RPN7 PF10602.9 CBY18163.1 - 1.9e-37 128.6 1.3 1.9e-37 128.6 1.3 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CBY18163.1 - 8.6e-10 39.1 0.4 2.3e-09 37.7 0.4 1.8 1 0 0 1 1 1 1 PCI domain TPR_12 PF13424.6 CBY18163.1 - 0.22 11.8 2.2 0.53 10.6 0.1 2.5 2 1 0 3 3 3 0 Tetratricopeptide repeat LEA_4 PF02987.16 CBY18163.1 - 0.98 9.6 6.2 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein TPR_2 PF07719.17 CBY18163.1 - 2.3 8.5 4.8 4 7.8 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PUF PF00806.19 CBY18164.1 - 3.9e-67 218.3 22.9 5.1e-10 38.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Acyl-CoA_dh_N PF02771.16 CBY18164.1 - 0.059 14.0 0.0 6.6 7.4 0.0 2.7 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain LOB PF03195.14 CBY18164.1 - 0.07 13.7 2.1 25 5.5 0.1 3.9 2 2 1 3 3 3 0 Lateral organ boundaries (LOB) domain PPK2 PF03976.14 CBY18164.1 - 0.09 12.3 0.2 0.31 10.5 0.1 2.0 1 1 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) sCache_2 PF17200.4 CBY18164.1 - 0.18 11.6 1.2 52 3.7 0.0 3.6 4 0 0 4 4 4 0 Single Cache domain 2 RNA_pol_Rpb1_7 PF04990.12 CBY18164.1 - 2.2 8.3 4.9 0.55 10.2 1.2 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 Motile_Sperm PF00635.26 CBY18165.1 - 0.043 13.7 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Kelch_1 PF01344.25 CBY18167.1 - 9.9e-14 50.7 2.2 0.0066 16.0 0.0 5.7 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 CBY18167.1 - 1.3e-13 50.9 4.5 2e-05 24.8 0.3 6.4 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY18167.1 - 2e-13 50.0 2.4 0.0057 16.6 0.0 5.1 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CBY18167.1 - 2.9e-12 46.4 2.8 0.00028 20.8 0.0 6.9 7 1 0 7 7 7 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY18167.1 - 1.4e-10 41.0 8.7 0.017 15.4 0.5 7.2 6 2 1 7 7 7 3 Kelch motif Kelch_2 PF07646.15 CBY18167.1 - 1.7e-06 27.7 8.0 6.1 7.0 0.0 7.3 7 1 0 7 7 7 2 Kelch motif Copine PF07002.16 CBY18168.1 - 2.3e-77 259.3 0.0 3e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 CBY18168.1 - 8.8e-15 54.9 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.9 CBY18168.1 - 8.2e-05 22.8 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus EB1 PF03271.17 CBY18169.1 - 1e-15 57.6 0.5 3.2e-15 56.1 0.5 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 CBY18169.1 - 3.4e-13 49.7 0.4 6.3e-13 48.9 0.4 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain ASFV_J13L PF05568.11 CBY18169.1 - 0.0061 16.3 1.2 0.0085 15.9 1.2 1.2 1 0 0 1 1 1 1 African swine fever virus J13L protein CAMSAP_CH PF11971.8 CBY18169.1 - 0.01 15.6 0.9 0.042 13.7 0.1 2.1 2 0 0 2 2 2 0 CAMSAP CH domain CH_2 PF06294.11 CBY18169.1 - 0.016 15.3 0.3 0.036 14.2 0.2 1.6 1 1 0 1 1 1 0 CH-like domain in sperm protein TMF_TATA_bd PF12325.8 CBY18169.1 - 0.027 14.7 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.6 CBY18169.1 - 0.029 14.5 0.7 0.057 13.5 0.7 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 LMP PF04778.12 CBY18169.1 - 0.096 12.6 0.5 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 LMP repeated region JIP_LZII PF16471.5 CBY18169.1 - 0.14 12.3 0.6 0.31 11.3 0.6 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DASH_Dad2 PF08654.10 CBY18169.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 U1snRNP70_N PF12220.8 CBY18170.1 - 1.5e-23 83.2 5.7 1.5e-23 83.2 5.7 3.4 3 1 1 4 4 4 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CBY18170.1 - 6.7e-19 67.5 0.4 1.4e-18 66.4 0.4 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2 PF00181.23 CBY18170.1 - 1.3 9.1 0.0 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 Ribosomal Proteins L2, RNA binding domain G-patch PF01585.23 CBY18171.1 - 2.9e-13 49.5 1.4 6.2e-13 48.4 1.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBY18171.1 - 1.6 8.9 7.5 0.18 11.9 1.2 2.6 2 1 0 2 2 2 0 G-patch domain PNP_UDP_1 PF01048.20 CBY18173.1 - 2.8e-23 82.4 0.0 3.6e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Gal-3-0_sulfotr PF06990.11 CBY18174.1 - 3.7e-74 250.0 0.1 4.3e-74 249.8 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY18174.1 - 0.00018 21.5 1.1 0.0019 18.1 1.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family TPR_12 PF13424.6 CBY18175.1 - 4.8e-29 100.5 28.2 1.3e-10 41.4 1.2 5.6 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 CBY18175.1 - 3.8e-23 79.8 19.7 0.00066 19.5 0.2 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBY18175.1 - 2e-21 74.9 32.5 9.7e-05 22.0 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 CBY18175.1 - 4.2e-14 51.4 32.5 0.042 14.0 0.0 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBY18175.1 - 1.8e-10 40.2 24.9 0.056 13.7 0.1 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat GoLoco PF02188.17 CBY18175.1 - 2e-08 33.6 16.0 0.00086 18.8 5.3 4.1 3 0 0 3 3 3 2 GoLoco motif TPR_10 PF13374.6 CBY18175.1 - 4.9e-07 29.4 25.5 0.92 9.5 0.1 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat Rapsyn_N PF10579.9 CBY18175.1 - 1.5e-05 25.0 1.6 0.12 12.5 0.0 4.5 3 2 2 5 5 5 1 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.6 CBY18175.1 - 3.2e-05 24.4 6.6 4.7 8.3 0.1 6.7 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY18175.1 - 5.3e-05 23.8 10.4 0.28 11.9 0.1 5.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY18175.1 - 0.00039 19.9 7.1 0.046 13.1 0.1 2.8 1 1 2 3 3 3 3 MalT-like TPR region TPR_11 PF13414.6 CBY18175.1 - 0.0015 18.1 24.3 3.5 7.4 0.0 7.5 8 1 0 8 8 8 2 TPR repeat CEP209_CC5 PF16574.5 CBY18175.1 - 0.015 15.5 7.0 0.015 15.5 7.0 2.3 2 1 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 ANAPC5 PF12862.7 CBY18175.1 - 0.082 13.0 10.2 0.3 11.2 0.5 4.0 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 PPR PF01535.20 CBY18175.1 - 0.46 10.9 1.8 63 4.1 0.0 4.2 5 0 0 5 5 5 0 PPR repeat Ac76 PF05814.11 CBY18175.1 - 0.46 10.5 7.3 3 7.9 1.9 2.6 2 0 0 2 2 2 0 Orf76 (Ac76) TPR_6 PF13174.6 CBY18175.1 - 0.83 10.4 7.7 1.4e+02 3.5 0.1 5.9 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY18175.1 - 9.7 6.8 13.3 85 3.9 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat p450 PF00067.22 CBY18176.1 - 3e-59 201.0 0.2 1.8e-58 198.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 UNC-93 PF05978.16 CBY18177.1 - 1.2e-23 83.6 8.2 1.2e-23 83.6 8.2 3.5 4 1 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CBY18177.1 - 5.6e-17 61.7 25.0 5.6e-17 61.7 25.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3989 PF13150.6 CBY18177.1 - 0.71 9.6 4.3 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) DUF2701 PF10857.8 CBY18177.1 - 1.7 8.7 7.6 38 4.4 1.4 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2701) WW PF00397.26 CBY18178.1 - 0.012 15.7 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 WW domain Phosphodiest PF01663.22 CBY18179.1 - 1.2e-61 209.3 0.0 1.8e-61 208.7 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 CBY18179.1 - 4.9e-07 30.1 16.0 1.2e-06 28.8 16.0 1.7 1 0 0 1 1 1 1 Somatomedin B domain Sulfotransfer_1 PF00685.27 CBY18180.1 - 1.3e-09 37.9 0.0 1.9e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY18180.1 - 1.7e-05 25.3 0.0 2.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY18181.1 - 9e-09 35.2 0.6 1.7e-08 34.3 0.2 1.6 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY18181.1 - 2.1e-06 28.3 0.0 3.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family UCH_1 PF13423.6 CBY18183.1 - 0.024 14.2 0.8 0.041 13.5 0.2 1.7 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF1279 PF06916.13 CBY18184.1 - 0.0068 16.9 0.8 0.011 16.2 0.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) GLEYA PF10528.9 CBY18185.1 - 0.026 14.9 0.5 1e+02 3.4 0.0 4.8 6 1 0 6 6 6 0 GLEYA domain DUF642 PF04862.12 CBY18185.1 - 0.24 11.2 2.2 1.2 8.9 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF642) TACC_C PF05010.14 CBY18186.1 - 4.6e-13 49.4 21.9 7.1e-13 48.8 21.9 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Glutaredoxin2_C PF04399.13 CBY18186.1 - 0.3 10.9 3.2 0.28 11.0 0.8 2.3 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Peptidase_S8 PF00082.22 CBY18187.1 - 5.6e-47 160.4 3.6 7.2e-47 160.1 3.6 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY18187.1 - 1.6e-20 72.9 0.0 3.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Pkinase_Tyr PF07714.17 CBY18189.1 - 2.5e-77 259.6 0.0 4.4e-77 258.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY18189.1 - 4.7e-37 127.8 0.0 8.9e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GTPase_binding PF09027.10 CBY18189.1 - 1e-07 31.8 0.0 2.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 GTPase binding Kinase-like PF14531.6 CBY18189.1 - 0.0037 16.6 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SAM_2 PF07647.17 CBY18189.1 - 0.0076 16.3 0.0 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) P4Ha_N PF08336.11 CBY18191.1 - 1.4e-30 106.1 0.5 3.1e-30 105.0 0.5 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CBY18191.1 - 9.1e-14 52.1 0.1 1.9e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Gemini_AL2 PF01440.16 CBY18191.1 - 0.0034 17.8 0.0 0.0066 16.9 0.0 1.4 1 0 0 1 1 1 1 Geminivirus AL2 protein CCDC50_N PF15295.6 CBY18191.1 - 0.05 13.8 0.1 0.097 12.8 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus TPR_2 PF07719.17 CBY18191.1 - 0.06 13.5 0.0 27 5.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 CBY18192.1 - 3.1e-17 62.2 0.1 4.6e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HORMA PF02301.18 CBY18193.1 - 0.019 14.6 0.4 0.027 14.1 0.4 1.2 1 0 0 1 1 1 0 HORMA domain TaqI_C PF12950.7 CBY18194.1 - 0.033 14.2 0.7 0.05 13.7 0.7 1.5 1 1 0 1 1 1 0 TaqI-like C-terminal specificity domain Alveol-reg_P311 PF11092.8 CBY18194.1 - 0.061 13.5 0.3 0.33 11.1 0.1 2.2 3 0 0 3 3 3 0 Neuronal protein 3.1 (p311) FAM195 PF14799.6 CBY18195.1 - 5.3e-06 26.7 0.3 6.9e-06 26.4 0.3 1.1 1 0 0 1 1 1 1 FAM195 family Toxin_15 PF07906.13 CBY18195.1 - 0.097 12.2 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region UPRTase PF14681.6 CBY18196.1 - 1.1e-62 211.2 0.0 1.5e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 CBY18196.1 - 1.2e-48 165.4 0.0 2.3e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CBY18196.1 - 0.0065 17.0 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CBY18196.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 CBY18196.1 - 0.017 15.5 0.4 0.68 10.4 0.4 2.7 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CBY18196.1 - 0.019 14.7 0.1 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 CBY18196.1 - 0.022 14.5 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBY18196.1 - 0.063 13.4 0.0 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 CBY18196.1 - 0.075 12.7 0.7 0.57 9.8 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase PRTase_2 PF15609.6 CBY18196.1 - 0.092 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase RNA_pol_L_2 PF13656.6 CBY18197.1 - 3.3e-28 97.3 0.1 4.2e-28 96.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CBY18197.1 - 1.5e-10 40.3 0.0 2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pacs-1 PF10254.9 CBY18198.1 - 3.7e-11 42.6 1.6 3.7e-11 42.6 1.6 3.5 2 1 1 3 3 3 1 PACS-1 cytosolic sorting protein F420_oxidored PF03807.17 CBY18198.1 - 0.22 12.1 0.4 0.59 10.8 0.4 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RRM_1 PF00076.22 CBY18199.1 - 1.6e-20 72.7 2.9 1.2e-09 37.8 0.3 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY18199.1 - 2.1e-08 33.8 0.2 4.8e-06 26.2 0.1 3.0 2 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CBY18199.1 - 2.7e-08 33.7 0.8 0.23 11.5 0.1 3.5 3 0 0 3 3 3 3 DbpA RNA binding domain RRM_3 PF08777.11 CBY18199.1 - 6e-05 23.0 2.8 0.0039 17.2 0.1 2.8 3 0 0 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 CBY18199.1 - 0.00072 19.4 0.0 0.64 9.9 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBY18199.1 - 0.0029 17.6 0.2 1.5 8.9 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 RNA_bind PF08675.11 CBY18199.1 - 0.16 12.0 0.1 1.1 9.4 0.0 2.2 3 0 0 3 3 3 0 RNA binding domain IMD PF08397.11 CBY18201.1 - 1.1e-15 57.6 0.1 1.8e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 IRSp53/MIM homology domain GTP_EFTU PF00009.27 CBY18202.1 - 1.8e-50 171.2 0.3 3.1e-50 170.4 0.3 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CBY18202.1 - 1.9e-13 50.2 0.0 4.9e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus LepA_C PF06421.12 CBY18202.1 - 7.1e-10 39.0 3.8 1.3e-08 34.9 3.8 2.5 1 1 0 1 1 1 1 GTP-binding protein LepA C-terminus MMR_HSR1 PF01926.23 CBY18202.1 - 6.4e-06 26.2 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CBY18202.1 - 1.7e-05 24.5 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 CBY18202.1 - 0.00095 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 CBY18202.1 - 0.012 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_II PF14492.6 CBY18202.1 - 0.022 14.8 0.0 0.061 13.4 0.0 1.8 1 1 0 1 1 1 0 Elongation Factor G, domain II FeoB_N PF02421.18 CBY18202.1 - 0.079 12.5 0.2 0.18 11.3 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B JmjC PF02373.22 CBY18203.1 - 1.7e-10 41.4 0.0 4.4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CBY18203.1 - 3.1e-09 36.9 0.1 3.1e-09 36.9 0.1 2.0 2 0 0 2 2 2 1 Cupin-like domain JHD PF17811.1 CBY18203.1 - 3.6e-07 30.6 0.2 1e-06 29.2 0.2 1.8 1 0 0 1 1 1 1 Jumonji helical domain PHD PF00628.29 CBY18203.1 - 0.00022 21.0 5.2 0.00071 19.4 5.2 1.9 1 0 0 1 1 1 1 PHD-finger YEATS PF03366.16 CBY18204.1 - 2.7e-33 113.8 1.5 4.7e-33 113.0 1.5 1.4 1 0 0 1 1 1 1 YEATS family Mod_r PF07200.13 CBY18204.1 - 0.019 15.1 0.2 0.031 14.4 0.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF3585 PF12130.8 CBY18205.1 - 7e-18 65.1 18.3 7e-18 65.1 18.3 4.4 3 1 1 5 5 5 1 Bivalent Mical/EHBP Rab binding domain DUF3659 PF12396.8 CBY18205.1 - 0.077 12.9 1.1 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) E1-E2_ATPase PF00122.20 CBY18205.1 - 0.098 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 E1-E2 ATPase BOP1NT PF08145.12 CBY18207.1 - 9e-95 317.5 13.5 9e-95 317.5 13.5 1.6 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 CBY18207.1 - 1.3e-23 82.8 2.0 5.3e-07 30.2 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY18207.1 - 9.1e-08 32.3 0.0 0.0023 18.2 0.0 3.8 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY18207.1 - 0.0007 19.5 0.0 0.018 15.0 0.1 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A zf-met PF12874.7 CBY18208.1 - 0.00017 21.9 4.2 1.7 9.1 0.1 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY18208.1 - 0.00035 20.8 7.3 0.34 11.2 0.5 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 CBY18208.1 - 0.012 15.3 0.0 0.043 13.5 0.0 2.0 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 CBY18208.1 - 0.016 16.0 16.3 0.098 13.5 0.4 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY18208.1 - 0.036 14.5 15.6 0.47 11.0 0.3 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CBY18208.1 - 0.056 13.2 0.4 0.056 13.2 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Zn-C2H2_12 PF18112.1 CBY18208.1 - 0.17 12.4 0.9 0.17 12.4 0.9 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 CBY18208.1 - 0.24 11.7 8.2 4.2 7.7 0.1 3.2 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Actin PF00022.19 CBY18209.1 - 2.4e-125 418.3 0.0 1e-124 416.3 0.0 1.7 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 CBY18209.1 - 0.00074 18.8 0.1 0.00097 18.4 0.1 1.2 1 0 0 1 1 1 1 Putative actin-like family MreB_Mbl PF06723.13 CBY18209.1 - 0.022 13.6 0.1 0.53 9.1 0.1 2.4 1 1 0 1 1 1 0 MreB/Mbl protein DUF4823 PF16105.5 CBY18209.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) WD40 PF00400.32 CBY18210.1 - 3.5e-33 113.1 23.1 1.5e-06 28.8 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY18210.1 - 1.3e-21 76.7 3.6 0.00027 21.2 0.5 6.3 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY18210.1 - 8.3e-09 35.6 0.5 0.00017 21.6 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBY18210.1 - 5e-08 32.3 0.5 0.21 10.5 0.0 4.2 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 CBY18210.1 - 0.0092 14.0 3.6 0.35 8.8 0.4 2.6 1 1 2 3 3 3 2 IKI3 family VID27 PF08553.10 CBY18210.1 - 0.018 14.1 0.0 0.9 8.5 0.0 2.2 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 CBY18210.1 - 0.045 13.7 0.0 8.7 6.4 0.0 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Reg_prop PF07494.11 CBY18210.1 - 0.049 13.9 0.5 1 9.8 0.1 3.2 3 0 0 3 3 3 0 Two component regulator propeller PH PF00169.29 CBY18212.1 - 1e-08 35.6 0.1 5.5e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 PH domain Anillin PF08174.11 CBY18212.1 - 0.00019 21.9 0.0 0.0007 20.0 0.0 2.1 1 0 0 1 1 1 1 Cell division protein anillin DUF4136 PF13590.6 CBY18213.1 - 0.14 12.7 0.0 0.17 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) UME PF08064.13 CBY18213.1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 UME (NUC010) domain CHGN PF05679.16 CBY18215.1 - 2.3e-95 320.4 0.3 5.6e-95 319.1 0.3 1.6 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY18215.1 - 1.3e-15 57.6 0.0 3.2e-15 56.3 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 CBY18215.1 - 5.1e-08 32.5 0.2 1.7e-07 30.8 0.2 1.9 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY18215.1 - 7.5e-06 25.9 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CBY18215.1 - 0.00019 21.0 0.5 0.25 10.8 0.0 2.6 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CBY18215.1 - 0.0041 16.6 0.0 2.2 7.7 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 21 Galactosyl_T PF01762.21 CBY18215.1 - 0.0083 16.0 0.0 0.86 9.4 0.0 3.3 3 1 0 3 3 3 1 Galactosyltransferase TSC22 PF01166.18 CBY18215.1 - 0.072 13.4 0.7 0.43 10.9 0.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family 7tm_1 PF00001.21 CBY18216.1 - 0.0013 18.1 4.3 0.002 17.5 4.3 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CBY18216.1 - 0.043 13.5 2.3 0.15 11.7 2.3 1.8 1 1 0 1 1 1 0 Olfactory receptor DIL PF01843.19 CBY18216.1 - 0.097 13.0 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 DIL domain DUF3099 PF11298.8 CBY18216.1 - 0.25 11.5 1.8 0.41 10.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) DUF3671 PF12420.8 CBY18217.1 - 0.044 13.9 0.2 0.044 13.9 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function SelP_N PF04592.14 CBY18217.1 - 0.46 9.9 8.1 1.1 8.6 8.1 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ferlin_C PF16165.5 CBY18217.1 - 2.2 8.2 6.3 29 4.6 0.0 2.4 2 0 0 2 2 2 0 Ferlin C-terminus Peptidase_S49_N PF08496.10 CBY18217.1 - 9.1 6.3 14.0 4.1 7.4 10.6 2.2 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Trypsin PF00089.26 CBY18218.1 - 5.5e-07 29.6 0.0 6.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin Amidase_2 PF01510.25 CBY18219.1 - 4e-15 56.4 0.3 7.8e-15 55.5 0.3 1.5 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase SIL1 PF16782.5 CBY18219.1 - 0.0043 16.3 0.2 0.0081 15.4 0.2 1.3 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Pkinase PF00069.25 CBY18220.1 - 3.6e-60 203.5 0.0 9e-60 202.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CBY18220.1 - 2.6e-34 117.1 0.1 1e-15 57.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY18220.1 - 2.1e-26 92.8 0.0 5.7e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY18220.1 - 0.0012 18.3 0.1 0.053 12.8 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Golgin_A5 PF09787.9 CBY18220.1 - 0.0052 16.3 11.0 0.011 15.2 11.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF745 PF05335.13 CBY18220.1 - 0.009 15.8 0.7 0.009 15.8 0.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF745) Seadorna_VP7 PF07387.11 CBY18220.1 - 0.02 14.0 0.0 0.054 12.5 0.0 1.7 1 0 0 1 1 1 0 Seadornavirus VP7 T4SS PF07996.11 CBY18220.1 - 0.025 15.0 1.6 0.056 13.9 1.6 1.6 1 0 0 1 1 1 0 Type IV secretion system proteins DUF4407 PF14362.6 CBY18220.1 - 0.027 13.8 7.6 0.049 13.0 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 CBY18220.1 - 0.042 13.9 14.8 0.18 11.9 14.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APH PF01636.23 CBY18220.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CHASE7 PF17151.4 CBY18220.1 - 0.064 12.9 0.9 0.13 11.9 0.9 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain Filament PF00038.21 CBY18220.1 - 0.072 12.7 11.0 0.12 11.9 11.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein Tho2 PF11262.8 CBY18220.1 - 0.078 12.2 2.9 0.14 11.3 2.9 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FliJ PF02050.16 CBY18220.1 - 0.098 12.9 8.9 0.65 10.2 2.0 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 CBY18220.1 - 0.29 10.6 5.6 0.56 9.7 5.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 CBY18220.1 - 0.33 11.0 19.2 0.11 12.6 8.0 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding LPP PF04728.13 CBY18220.1 - 0.51 10.8 4.5 3.7 8.0 0.4 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.11 CBY18220.1 - 0.59 10.4 7.1 1.6 9.1 0.7 2.7 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 CBY18220.1 - 2.1 8.4 14.9 0.033 14.3 4.2 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CCDC-167 PF15188.6 CBY18220.1 - 2.6 8.4 6.6 7.8 6.9 6.6 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 THOC7 PF05615.13 CBY18220.1 - 3.6 7.9 13.3 63 3.9 13.4 2.4 1 1 0 1 1 1 0 Tho complex subunit 7 SlyX PF04102.12 CBY18220.1 - 4 8.1 8.2 20 5.9 1.3 2.9 2 0 0 2 2 2 0 SlyX TBCA PF02970.16 CBY18220.1 - 6.8 7.1 14.9 0.83 10.0 9.8 2.2 2 0 0 2 2 1 0 Tubulin binding cofactor A Fib_alpha PF08702.10 CBY18220.1 - 7.9 6.7 8.8 22 5.2 8.8 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 CBY18220.1 - 7.9 5.6 8.6 22 4.1 8.5 1.7 1 1 0 1 1 1 0 TMPIT-like protein TMF_TATA_bd PF12325.8 CBY18220.1 - 8.1 6.7 15.3 1.3 9.2 10.5 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FAM76 PF16046.5 CBY18220.1 - 9.6 5.5 13.6 44 3.3 13.6 1.9 1 1 0 1 1 1 0 FAM76 protein Na_Ca_ex PF01699.24 CBY18221.1 - 1.3e-16 60.9 15.1 2.3e-16 60.1 15.1 1.4 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DPM3 PF08285.11 CBY18221.1 - 0.097 12.9 1.7 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) VWA PF00092.28 CBY18222.1 - 2.5e-31 109.2 3.0 2.2e-10 41.0 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 CBY18222.1 - 1.2e-16 61.3 0.1 1.9e-06 28.5 0.0 4.1 5 0 0 5 5 5 3 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY18222.1 - 0.00058 19.3 2.9 0.097 12.1 0.1 2.6 3 0 0 3 3 3 2 VWA domain containing CoxE-like protein DUF1515 PF07439.11 CBY18223.1 - 0.14 12.2 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) KH_1 PF00013.29 CBY18224.1 - 2.4e-27 94.6 0.4 1.1e-14 54.0 0.7 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBY18224.1 - 4.2e-08 32.9 1.3 7.8e-05 22.4 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CBY18224.1 - 6.6e-06 25.9 0.5 0.025 14.5 0.1 2.7 2 1 0 2 2 2 2 KH domain DUF4537 PF15057.6 CBY18224.1 - 0.031 14.3 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) KH_5 PF13184.6 CBY18224.1 - 0.043 13.9 0.4 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 NusA-like KH domain Rox3 PF08633.10 CBY18224.1 - 0.062 13.6 1.4 0.1 12.9 1.4 1.3 1 0 0 1 1 1 0 Rox3 mediator complex subunit RNR_inhib PF08591.10 CBY18224.1 - 0.08 14.2 0.8 0.18 13.1 0.8 1.6 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor HAUS6_N PF14661.6 CBY18224.1 - 0.14 11.7 3.9 0.21 11.2 3.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DWNN PF08783.11 CBY18225.1 - 2.2e-25 88.8 0.2 7.2e-25 87.1 0.2 2.0 1 0 0 1 1 1 1 DWNN domain U-box PF04564.15 CBY18225.1 - 2.3e-05 24.5 0.1 0.0001 22.4 0.1 2.2 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 CBY18225.1 - 0.0051 16.6 14.9 0.0083 15.9 14.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY18225.1 - 0.0079 16.0 12.4 0.012 15.4 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY18225.1 - 0.037 14.0 8.2 0.089 12.8 7.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY18225.1 - 0.35 10.8 13.0 0.63 10.0 13.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY18225.1 - 0.5 10.6 12.5 0.89 9.8 12.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CBY18225.1 - 0.76 9.6 11.1 1.4 8.8 11.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 CBY18225.1 - 0.98 8.9 12.2 0.22 11.0 2.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DUF498 PF04430.14 CBY18226.1 - 5.6e-14 52.1 0.0 9.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Methyltransf_4 PF02390.17 CBY18227.1 - 4.5e-54 182.5 0.0 6e-54 182.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CBY18227.1 - 1.4e-06 28.9 0.0 1e-05 26.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CBY18227.1 - 0.00029 20.4 0.0 0.00085 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CBY18227.1 - 0.0008 19.3 0.0 0.0015 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY18227.1 - 0.00089 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY18227.1 - 0.00097 19.8 0.0 0.0025 18.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBY18227.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CBY18227.1 - 0.0026 18.4 0.0 0.017 15.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBY18227.1 - 0.0073 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 CBY18227.1 - 0.027 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 CBY18227.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 UDPGP PF01704.18 CBY18230.1 - 6.9e-56 189.7 0.0 9.1e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CBY18230.1 - 0.00033 21.0 0.0 0.00062 20.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DDA1 PF10172.9 CBY18231.1 - 7e-20 71.1 0.9 1.2e-19 70.3 0.9 1.4 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase PIP5K PF01504.18 CBY18232.1 - 5.1e-35 121.0 2.8 7.2e-35 120.5 2.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MtN3_slv PF03083.16 CBY18233.1 - 4.8e-38 129.1 14.4 2.3e-21 75.6 0.8 2.3 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange UPF0139 PF03669.13 CBY18233.1 - 0.11 12.4 0.2 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) SR-25 PF10500.9 CBY18234.1 - 0.0025 17.5 23.3 0.0025 17.5 23.3 3.2 1 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein AT_hook PF02178.19 CBY18234.1 - 0.074 13.0 4.9 0.31 11.1 4.9 2.2 1 0 0 1 1 1 0 AT hook motif Herpes_pp85 PF04637.12 CBY18234.1 - 3.6 5.9 9.0 5.9 5.2 9.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ribosomal_L23 PF00276.20 CBY18235.1 - 2.9e-17 62.8 4.3 2.6e-16 59.8 4.3 2.0 1 1 0 1 1 1 1 Ribosomal protein L23 YihI PF04220.12 CBY18235.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Ribosomal_S7e PF01251.18 CBY18236.1 - 7.3e-81 270.3 6.0 8.2e-81 270.2 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ribosomal_S13 PF00416.22 CBY18237.1 - 4.2e-50 169.4 5.0 4.8e-50 169.2 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FliG_C PF01706.16 CBY18237.1 - 0.011 15.9 0.1 6.5 7.0 0.0 2.2 2 0 0 2 2 2 0 FliG C-terminal domain HHH_6 PF14579.6 CBY18237.1 - 0.086 13.1 0.1 0.21 11.9 0.1 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix motif DnaJ PF00226.31 CBY18239.1 - 2.2e-16 59.7 4.7 5.9e-16 58.3 4.7 1.8 1 0 0 1 1 1 1 DnaJ domain Aquarius_N PF16399.5 CBY18240.1 - 5.2e-291 967.4 6.4 8e-291 966.8 6.4 1.3 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 CBY18240.1 - 9e-29 101.0 0.5 2.5e-27 96.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.6 CBY18240.1 - 9.5e-28 97.2 0.0 3.7e-27 95.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY18240.1 - 5e-08 33.4 0.0 2.2e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBY18240.1 - 4.4e-07 29.8 0.0 0.00055 19.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 CBY18240.1 - 4.7e-06 26.7 0.0 1.6e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaB_C PF03796.15 CBY18240.1 - 0.002 17.5 0.0 0.0049 16.2 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DUF2075 PF09848.9 CBY18240.1 - 0.0027 17.0 1.1 0.0077 15.5 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 CBY18240.1 - 0.0041 16.9 0.1 0.0086 15.9 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 CBY18240.1 - 0.0063 16.9 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 CBY18240.1 - 0.0094 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Parvo_NS1 PF01057.17 CBY18240.1 - 0.036 13.2 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 CBY18240.1 - 0.044 13.2 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 CBY18240.1 - 0.055 13.7 0.1 0.64 10.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain LktC PF06261.11 CBY18240.1 - 0.056 13.4 0.1 3.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC AAA_16 PF13191.6 CBY18240.1 - 0.056 13.8 0.1 0.59 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain RecA PF00154.21 CBY18240.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Adeno_IVa2 PF02456.15 CBY18240.1 - 0.06 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Viral_helicase1 PF01443.18 CBY18240.1 - 0.12 12.1 0.0 5.6 6.6 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 CBY18240.1 - 0.15 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 KaiC ADH_zinc_N PF00107.26 CBY18241.1 - 9.4e-21 74.1 0.1 1.7e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBY18241.1 - 2.9e-16 60.7 0.0 7.8e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBY18241.1 - 4.6e-12 45.8 0.0 7.6e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 CBY18241.1 - 0.01 15.1 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain EF-hand_8 PF13833.6 CBY18242.1 - 1.7e-09 37.4 7.7 0.00029 20.6 0.1 4.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 CBY18242.1 - 2.9e-09 37.2 12.3 0.00028 21.3 0.6 4.6 3 3 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY18242.1 - 1.3e-08 33.8 22.7 0.00014 21.2 0.2 5.8 7 0 0 7 7 7 2 EF hand EF-hand_6 PF13405.6 CBY18242.1 - 7e-07 28.7 17.2 0.0018 18.1 0.1 4.9 6 0 0 6 6 6 2 EF-hand domain EF-hand_5 PF13202.6 CBY18242.1 - 0.00029 20.2 7.7 0.44 10.1 0.1 4.3 4 0 0 4 4 4 2 EF hand IFT43 PF15305.6 CBY18244.1 - 8.1e-05 22.8 0.9 0.0001 22.5 0.3 1.4 2 0 0 2 2 2 1 Intraflagellar transport protein 43 Peptidase_C1 PF00112.23 CBY18245.1 - 1.3e-60 205.2 4.6 1.7e-60 204.8 4.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 CBY18245.1 - 9.1e-10 38.3 0.4 9.1e-10 38.3 0.4 1.7 2 0 0 2 2 2 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 CBY18245.1 - 0.27 10.0 2.6 0.45 9.2 0.2 1.9 2 0 0 2 2 2 0 Peptidase C1-like family zf-C4 PF00105.18 CBY18246.1 - 1.4e-21 76.7 15.2 2.3e-21 76.0 15.2 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY18246.1 - 0.0016 18.1 2.5 0.0027 17.3 0.2 2.2 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 CBY18246.1 - 0.93 9.6 8.6 2.4 8.3 8.6 1.7 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type S1 PF00575.23 CBY18247.1 - 8.2e-05 22.9 0.0 0.8 10.1 0.0 2.5 2 0 0 2 2 2 2 S1 RNA binding domain Glyco_tranf_2_4 PF13704.6 CBY18247.1 - 0.0022 18.5 0.8 3.3 8.3 0.1 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 2 HU-CCDC81_bac_2 PF18175.1 CBY18247.1 - 0.0038 17.0 13.0 10 6.1 0.1 5.4 5 0 0 5 5 5 2 CCDC81-like prokaryotic HU domain 2 EABR PF12180.8 CBY18247.1 - 0.0045 16.6 1.4 3.2 7.4 0.1 3.0 2 0 0 2 2 2 2 TSG101 and ALIX binding domain of CEP55 DUF503 PF04456.12 CBY18247.1 - 0.019 14.8 3.9 4 7.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF503) CsrA PF02599.16 CBY18247.1 - 0.098 12.6 0.1 27 4.8 0.0 2.6 2 0 0 2 2 2 0 Global regulator protein family DUF3755 PF12579.8 CBY18247.1 - 0.54 9.9 5.8 7.6 6.3 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) MINDY_DUB PF04424.13 CBY18247.1 - 0.56 10.2 5.6 13 5.9 0.1 3.1 3 0 0 3 3 3 0 MINDY deubiquitinase Bac_DNA_binding PF00216.21 CBY18247.1 - 0.69 10.2 4.6 24 5.2 0.2 3.2 3 0 0 3 3 3 0 Bacterial DNA-binding protein DUF1648 PF07853.11 CBY18247.1 - 0.73 9.5 1.4 62 3.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1648) DUF4672 PF15716.5 CBY18247.1 - 1.1 8.9 5.4 13 5.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4672) HHA PF05321.11 CBY18247.1 - 1.5 9.2 9.8 30 5.0 0.1 5.0 5 0 0 5 5 5 0 Haemolysin expression modulating protein RasGAP PF00616.19 CBY18248.1 - 3.1e-19 69.5 0.2 1.2e-08 35.0 0.0 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CBY18248.1 - 8.1e-06 26.1 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain PP2C PF00481.21 CBY18249.1 - 1.9e-28 99.8 0.0 2.2e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Hairy_orange PF07527.13 CBY18249.1 - 0.16 12.2 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 Hairy Orange RRM_1 PF00076.22 CBY18251.1 - 6e-15 54.8 0.1 9.1e-15 54.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY18251.1 - 9.7e-05 22.3 0.1 0.00017 21.5 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CBY18251.1 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBY18251.1 - 0.024 14.7 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Limkain b1 Lyase_aromatic PF00221.19 CBY18252.1 - 1.6e-169 564.5 1.1 1.9e-169 564.3 1.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase RUN PF02759.19 CBY18255.1 - 0.053 13.5 0.1 0.075 13.0 0.1 1.2 1 0 0 1 1 1 0 RUN domain MAM33 PF02330.16 CBY18256.1 - 0.0015 18.5 0.1 0.002 18.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF5638 PF18688.1 CBY18256.1 - 0.075 13.4 0.3 1.9 8.8 0.1 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5638) C1q PF00386.21 CBY18257.1 - 3.9e-14 53.0 0.4 7.7e-14 52.0 0.4 1.5 1 0 0 1 1 1 1 C1q domain Matrilin_ccoil PF10393.9 CBY18257.1 - 0.00024 20.9 1.5 0.97 9.3 0.0 3.4 3 0 0 3 3 3 2 Trimeric coiled-coil oligomerisation domain of matrilin SlyX PF04102.12 CBY18257.1 - 0.012 16.3 2.8 3.3 8.4 0.3 2.8 1 1 1 2 2 2 0 SlyX MscS_porin PF12795.7 CBY18257.1 - 0.018 14.6 2.4 0.027 14.0 2.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Med4 PF10018.9 CBY18257.1 - 0.065 12.9 1.7 0.1 12.2 1.7 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.12 CBY18257.1 - 0.21 12.1 8.1 4 8.0 1.4 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 CBY18257.1 - 0.39 11.2 6.3 19 5.8 0.1 4.0 2 1 2 4 4 4 0 Lipoprotein leucine-zipper PSD2 PF07624.11 CBY18258.1 - 0.027 14.2 1.4 0.86 9.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Phage_holin_3_6 PF07332.11 CBY18258.1 - 0.55 10.3 9.2 0.79 9.8 2.2 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Metal_resist PF13801.6 CBY18258.1 - 0.65 10.2 2.6 0.43 10.8 0.6 1.6 2 0 0 2 2 2 0 Heavy-metal resistance LRR_8 PF13855.6 CBY18259.1 - 1.2e-11 44.2 0.4 9.1e-06 25.3 0.0 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBY18259.1 - 0.0023 18.3 0.9 0.28 11.7 0.1 2.8 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) zf-C2H2_4 PF13894.6 CBY18261.1 - 1.4e-09 38.0 36.3 0.00046 20.8 1.0 6.8 6 0 0 6 6 6 4 C2H2-type zinc finger zf-Di19 PF05605.12 CBY18261.1 - 6.4e-09 36.0 22.4 0.15 12.3 0.0 6.3 6 0 0 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CBY18261.1 - 2.3e-06 27.8 43.3 0.00029 21.1 1.1 6.6 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY18261.1 - 1.9e-05 24.9 17.8 0.37 11.3 0.0 5.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY18261.1 - 4.5e-05 23.7 21.0 1.2 9.6 0.1 5.7 3 1 2 5 5 5 2 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.14 CBY18261.1 - 0.00016 21.4 13.1 0.35 10.7 0.2 5.5 5 0 0 5 5 5 2 Rad50 zinc hook motif GAGA PF09237.11 CBY18261.1 - 0.00054 19.7 11.2 2.5 8.0 0.1 5.4 5 0 0 5 5 5 2 GAGA factor BIR PF00653.21 CBY18261.1 - 0.009 16.6 8.3 3.5 8.4 0.0 5.1 5 0 0 5 5 5 1 Inhibitor of Apoptosis domain Zn-ribbon_8 PF09723.10 CBY18261.1 - 0.015 15.4 12.9 5.5 7.2 0.3 6.4 6 0 0 6 6 6 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CBY18261.1 - 0.086 13.3 28.1 1.9 9.0 0.5 8.3 7 4 0 7 7 6 0 Zinc-finger double domain OrsD PF12013.8 CBY18261.1 - 0.17 12.4 15.5 8.4 6.9 0.4 5.5 4 1 2 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D Zf_RING PF16744.5 CBY18261.1 - 0.35 11.0 5.7 6.8 6.9 0.1 3.9 4 0 0 4 4 4 0 KIAA1045 RING finger DUF2225 PF09986.9 CBY18261.1 - 0.57 9.9 5.8 60 3.3 0.4 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_9 PF16293.5 CBY18261.1 - 0.58 10.0 18.6 6 6.8 0.2 5.8 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 CBY18261.1 - 1.1 9.6 16.6 2.2 8.7 0.0 4.8 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding Prok-RING_4 PF14447.6 CBY18261.1 - 3.5 7.6 16.1 4.3 7.3 0.2 4.9 5 0 0 5 5 5 0 Prokaryotic RING finger family 4 DUF2180 PF09947.9 CBY18261.1 - 4.4 7.4 5.6 0.97 9.4 0.4 2.6 3 0 0 3 3 2 0 Uncharacterized protein conserved in archaea (DUF2180) FYVE PF01363.21 CBY18261.1 - 7.9 6.7 17.7 5.9 7.1 0.2 5.2 5 2 1 6 6 5 0 FYVE zinc finger DOMON PF03351.17 CBY18262.1 - 2.1e-07 31.2 0.0 3.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 DOMON domain NOA36 PF06524.12 CBY18262.1 - 2.5 7.3 6.1 3.3 6.9 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1349 PF07081.11 CBY18263.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) DUF3105 PF11303.8 CBY18263.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) Ion_trans PF00520.31 CBY18264.1 - 4.1e-06 26.2 12.7 0.0024 17.2 0.1 2.2 2 0 0 2 2 2 2 Ion transport protein DUF262 PF03235.14 CBY18264.1 - 0.35 11.0 5.5 0.14 12.3 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF262 Ion_trans PF00520.31 CBY18265.1 - 1.5e-05 24.3 0.2 3.5e-05 23.2 0.2 1.6 2 0 0 2 2 2 1 Ion transport protein FliD_N PF02465.18 CBY18265.1 - 0.017 15.8 2.0 0.028 15.1 2.0 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus RNA_pol_3_Rpc31 PF11705.8 CBY18265.1 - 0.022 15.0 1.2 0.034 14.4 1.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sushi PF00084.20 CBY18267.1 - 1.2e-63 211.6 127.7 5.4e-08 33.3 3.9 14.5 14 0 0 14 14 14 14 Sushi repeat (SCR repeat) SAM_1 PF00536.30 CBY18268.1 - 3.4e-13 49.8 0.0 9.6e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY18268.1 - 6.3e-11 42.2 0.1 1.9e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Endonuc_Holl PF10107.9 CBY18268.1 - 5.6 6.8 9.7 10 5.9 0.6 3.2 3 1 0 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase Ank_4 PF13637.6 CBY18269.1 - 5.2e-19 68.4 0.4 8.2e-09 35.8 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY18269.1 - 5.9e-15 55.6 0.2 2e-11 44.3 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY18269.1 - 6.4e-12 45.3 3.0 6.3e-06 26.4 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 CBY18269.1 - 9.1e-11 41.8 0.1 2.2e-09 37.4 0.0 2.8 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY18269.1 - 3.7e-10 39.2 2.6 0.00018 21.7 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat GARS_A PF01071.19 CBY18270.1 - 0.068 12.9 0.1 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain BBS2_C PF14782.6 CBY18271.1 - 1.5e-105 353.4 1.2 1.5e-105 353.4 1.2 1.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 CBY18271.1 - 7.3e-34 116.1 0.1 2.5e-32 111.1 0.1 2.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 CBY18271.1 - 2.4e-25 88.4 0.1 1.9e-23 82.4 0.0 3.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal ANAPC4_WD40 PF12894.7 CBY18271.1 - 0.0034 17.6 0.1 0.36 11.1 0.0 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 CBY18271.1 - 0.0083 15.8 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 CNH domain KH_8 PF17903.1 CBY18272.1 - 1.9e-30 104.8 0.1 1.9e-30 104.8 0.1 3.0 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 CBY18272.1 - 0.00045 20.0 0.1 0.0013 18.5 0.1 1.8 1 0 0 1 1 1 1 KH domain PXPV PF12778.7 CBY18273.1 - 1 9.3 5.7 1.8 8.5 5.7 1.3 1 0 0 1 1 1 0 PXPV repeat (3 copies) DRMBL PF07522.14 CBY18274.1 - 0.048 13.8 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase AhpC-TSA PF00578.21 CBY18275.1 - 1.5e-26 92.8 0.0 2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CBY18275.1 - 2.8e-13 49.5 0.0 5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CBY18275.1 - 3.3e-07 30.1 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin zf-C2H2_4 PF13894.6 CBY18276.1 - 2.7e-08 34.0 39.5 0.0069 17.1 0.4 7.8 7 1 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY18276.1 - 6.1e-06 26.4 38.0 0.013 15.9 1.0 7.7 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 CBY18276.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.0 3 1 0 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CBY18276.1 - 0.66 10.3 31.5 0.29 11.5 7.1 5.9 3 3 3 6 6 6 0 C2H2 type zinc-finger (2 copies) BRCT_2 PF16589.5 CBY18277.1 - 8.8e-05 22.8 0.4 0.57 10.6 0.1 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY18277.1 - 0.014 15.6 0.3 0.92 9.8 0.1 3.0 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 CBY18277.1 - 0.089 12.9 0.0 5.2 7.2 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Nup192 PF11894.8 CBY18278.1 - 3.7e-192 641.0 31.9 1.5e-97 327.4 14.3 4.3 3 1 1 4 4 4 3 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF4295 PF14128.6 CBY18278.1 - 0.0033 17.2 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4295) GcnA_N PF18229.1 CBY18278.1 - 0.08 13.0 0.3 0.27 11.3 0.3 1.9 1 0 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain Chordopox_L2 PF05803.12 CBY18278.1 - 0.64 9.9 2.8 36 4.3 0.2 3.1 2 0 0 2 2 2 0 Chordopoxvirus L2 protein TPR_1 PF00515.28 CBY18281.1 - 1.1e-20 72.5 11.8 1.5e-09 37.3 2.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY18281.1 - 4e-16 57.8 7.6 3.7e-06 26.6 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBY18281.1 - 2.1e-14 52.9 7.4 1.9e-06 27.5 0.3 3.5 1 1 2 3 3 3 3 TPR repeat SGTA_dimer PF16546.5 CBY18281.1 - 8.9e-13 47.8 0.3 4.2e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_8 PF13181.6 CBY18281.1 - 2.1e-12 46.2 11.3 2.5e-06 27.3 0.9 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY18281.1 - 1.7e-08 33.9 2.3 0.00086 19.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY18281.1 - 2e-08 34.4 3.2 1.5e-06 28.4 2.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY18281.1 - 1e-06 28.7 5.0 0.047 14.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBY18281.1 - 3.3e-06 26.8 4.9 0.023 14.5 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY18281.1 - 3.9e-06 27.2 0.3 0.13 13.1 0.0 4.3 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY18281.1 - 2.5e-05 24.7 1.2 0.0011 19.4 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY18281.1 - 4.2e-05 22.9 0.2 0.0036 16.6 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY18281.1 - 0.00014 21.9 6.8 0.093 12.8 0.9 3.1 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CBY18281.1 - 0.0014 19.3 0.0 0.23 12.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Egg_lysin PF01303.17 CBY18281.1 - 0.007 16.6 0.2 0.007 16.6 0.2 2.3 1 1 0 2 2 2 1 Egg lysin (Sperm-lysin) SHNi-TPR PF10516.9 CBY18281.1 - 0.016 14.6 0.7 2.2 7.8 0.1 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_9 PF13371.6 CBY18281.1 - 0.028 14.5 0.3 1.2 9.3 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat PSD4 PF07631.11 CBY18281.1 - 0.037 14.6 4.1 5 7.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) TOM20_plant PF06552.12 CBY18281.1 - 0.24 11.2 5.0 0.8 9.4 0.4 3.1 1 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF3856 PF12968.7 CBY18281.1 - 0.61 10.1 7.3 1.3 9.1 2.3 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 CBY18281.1 - 1 9.5 11.6 2.6 8.2 0.1 3.5 1 1 2 3 3 3 0 MIT (microtubule interacting and transport) domain INCENP_ARK-bind PF03941.15 CBY18282.1 - 4.4e-09 36.1 0.1 1.2e-08 34.7 0.1 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SAP PF02037.27 CBY18282.1 - 3e-05 23.6 0.7 5.3e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 SAP domain IBB PF01749.20 CBY18282.1 - 0.01 16.2 11.0 0.045 14.2 11.0 2.2 1 0 0 1 1 1 0 Importin beta binding domain LRR_8 PF13855.6 CBY18283.1 - 1.1e-09 37.8 7.5 0.00046 19.9 0.8 3.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBY18283.1 - 6.1e-08 32.8 11.3 0.00024 21.4 1.5 3.7 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBY18283.1 - 3.3e-05 23.6 5.7 2 8.7 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 CBY18283.1 - 0.0046 17.3 3.7 20 6.2 0.1 5.1 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 CBY18283.1 - 0.025 14.1 2.0 0.054 13.0 1.4 1.7 1 1 0 1 1 1 0 Leucine-rich repeat DPBB_1 PF03330.18 CBY18283.1 - 0.075 13.3 0.0 0.76 10.1 0.0 2.2 2 0 0 2 2 2 0 Lytic transglycolase DUF739 PF05339.11 CBY18283.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF739) LRR_8 PF13855.6 CBY18284.1 - 3.8e-12 45.8 3.7 4.5e-12 45.5 3.7 1.1 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 CBY18284.1 - 0.00027 21.2 1.2 0.00027 21.2 1.2 1.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY18284.1 - 0.0072 16.7 2.5 0.075 13.6 1.1 2.8 2 1 0 2 2 2 1 Leucine Rich Repeat LRR_6 PF13516.6 CBY18284.1 - 0.019 15.0 3.8 0.18 11.9 1.0 2.5 2 0 0 2 2 2 0 Leucine Rich repeat Arm PF00514.23 CBY18285.1 - 4.7e-53 175.7 29.0 0.00037 20.4 0.0 13.4 13 0 0 13 13 13 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CBY18285.1 - 3.7e-16 59.3 14.0 1.9e-06 28.1 0.1 7.4 2 2 8 10 10 10 5 HEAT repeats Adaptin_N PF01602.20 CBY18285.1 - 3.1e-11 42.6 5.3 2.2e-07 29.8 0.0 3.7 1 1 0 3 3 3 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 CBY18285.1 - 3.1e-09 37.0 8.2 3.6 7.7 0.1 7.0 4 2 2 7 7 7 3 V-ATPase subunit H HEAT PF02985.22 CBY18285.1 - 6.1e-09 35.4 11.9 0.21 12.0 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 CBY18285.1 - 1.1e-07 32.2 12.6 0.0048 17.4 0.2 7.7 8 1 0 8 8 8 1 HEAT-like repeat Proteasom_PSMB PF10508.9 CBY18285.1 - 2.1e-06 26.5 3.2 6.4e-06 24.9 0.3 2.5 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit Arm_2 PF04826.13 CBY18285.1 - 2.1e-06 27.4 10.4 0.048 13.1 0.1 5.7 3 2 2 6 6 6 1 Armadillo-like KAP PF05804.12 CBY18285.1 - 2.4e-06 26.0 0.6 1.2 7.2 0.0 3.9 1 1 1 4 4 4 4 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 CBY18285.1 - 1.9e-05 24.1 0.3 0.78 9.0 0.0 4.4 1 1 3 4 4 4 2 V-ATPase subunit H Cnd1 PF12717.7 CBY18285.1 - 0.00036 20.6 4.2 1.9 8.5 0.1 4.4 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CTNNBL PF08216.11 CBY18285.1 - 0.0011 19.1 0.1 21 5.4 0.0 5.0 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear E3_UbLigase_R4 PF13764.6 CBY18285.1 - 0.014 13.6 3.4 0.06 11.5 0.0 2.9 2 1 1 3 3 3 0 E3 ubiquitin-protein ligase UBR4 UPF0147 PF03685.13 CBY18285.1 - 0.059 13.4 0.8 7.8 6.6 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0147) Pes-10 PF07149.11 CBY18285.1 - 7.8 5.4 7.2 0.92 8.5 1.1 2.5 3 1 0 3 3 3 0 Pes-10 ANAPC4_WD40 PF12894.7 CBY18286.1 - 1.1e-05 25.6 0.1 0.81 10.0 0.1 4.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 CBY18286.1 - 0.00032 19.6 0.7 1.6 7.4 0.0 4.3 2 2 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.32 CBY18286.1 - 0.0065 17.3 0.3 76 4.4 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 CBY18286.1 - 0.02 14.8 1.1 2.9 7.9 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 CBY18286.1 - 0.02 14.0 1.8 2.4 7.1 0.0 2.9 2 1 1 3 3 3 0 Coatomer WD associated region DUF4904 PF16247.5 CBY18286.1 - 0.022 14.6 0.2 1.2 8.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4904) Thiolase_C PF02803.18 CBY18286.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiolase, C-terminal domain PHD PF00628.29 CBY18287.1 - 3.9e-09 36.3 12.7 9.5e-09 35.0 12.7 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CBY18287.1 - 0.0028 17.9 3.7 0.0066 16.7 3.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBY18287.1 - 0.057 13.6 4.8 0.095 12.9 4.8 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD_2 PF13831.6 CBY18287.1 - 5.1 6.7 14.3 0.43 10.2 8.6 2.1 2 1 0 2 2 2 0 PHD-finger FHA PF00498.26 CBY18288.1 - 2.1e-06 28.0 0.0 0.00013 22.2 0.0 2.6 2 0 0 2 2 2 1 FHA domain PHD PF00628.29 CBY18288.1 - 7.3e-05 22.6 0.8 0.00024 20.9 0.8 1.9 1 0 0 1 1 1 1 PHD-finger ADH_N_2 PF16884.5 CBY18289.1 - 2.6e-25 88.4 0.0 2e-24 85.6 0.0 2.2 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CBY18289.1 - 1.9e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBY18289.1 - 8.1e-09 36.6 0.0 1.3e-08 35.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PIG-L PF02585.17 CBY18290.1 - 5.5e-24 85.3 0.0 7.5e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase WD40 PF00400.32 CBY18291.1 - 1.7e-32 110.9 9.3 5.9e-09 36.4 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY18291.1 - 9.8e-16 57.8 0.3 0.0049 17.1 0.0 5.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 CBY18291.1 - 3.5e-15 55.4 0.5 6.5e-15 54.5 0.5 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 CBY18291.1 - 3.3e-09 36.1 1.2 0.0086 15.1 0.0 3.9 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY18291.1 - 1.4e-08 33.8 0.0 0.013 14.2 0.0 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CBY18291.1 - 1.5e-05 25.0 1.4 0.017 15.0 0.2 3.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY18291.1 - 0.012 14.9 2.3 0.17 11.1 1.1 2.7 2 1 0 2 2 2 0 WD40-like domain PD40 PF07676.12 CBY18291.1 - 0.015 15.2 0.0 28 4.8 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF4221 PF13970.6 CBY18291.1 - 0.046 13.3 0.6 0.18 11.3 0.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4221) LTD PF00932.19 CBY18291.1 - 0.081 13.3 0.1 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Lamin Tail Domain Hira PF07569.11 CBY18291.1 - 0.089 12.5 0.2 16 5.1 0.0 3.6 4 0 0 4 4 4 0 TUP1-like enhancer of split Proteasome_A_N PF10584.9 CBY18291.1 - 0.12 12.1 0.3 1.1e+02 2.6 0.1 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF2462 PF09495.10 CBY18292.1 - 1.2e-11 45.1 17.6 1.4e-11 44.9 17.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) PRCC PF10253.9 CBY18293.1 - 4.7e-28 99.4 0.2 4.7e-28 99.4 0.2 3.4 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.25 CBY18295.1 - 9e-67 225.2 0.2 1.1e-66 225.0 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18295.1 - 4.2e-20 72.1 0.0 5.6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY18295.1 - 7.6e-09 35.8 0.1 1.4e-06 28.4 0.1 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY18295.1 - 0.00027 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY18295.1 - 0.00049 19.7 1.1 0.0043 16.7 0.1 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CBY18295.1 - 0.0034 16.2 0.0 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CBY18295.1 - 0.048 13.0 0.1 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Dynein_light PF01221.18 CBY18296.1 - 3.3e-44 149.1 1.1 3.7e-44 149.0 1.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4677 PF15726.5 CBY18298.1 - 4.3 7.5 8.5 0.46 10.6 2.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4677) NUFIP1 PF10453.9 CBY18299.1 - 0.2 11.5 0.2 7.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) ATP-gua_Ptrans PF00217.19 CBY18300.1 - 2.8e-62 209.9 0.0 4e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY18300.1 - 2e-21 76.1 0.0 3.8e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Peptidase_M1 PF01433.20 CBY18303.1 - 1.5e-40 139.1 1.2 4e-40 137.7 1.2 1.7 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY18303.1 - 1e-18 68.2 1.6 3.4e-18 66.5 0.1 2.4 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain Galactosyl_T PF01762.21 CBY18304.1 - 5e-09 36.3 0.0 7.9e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase Chitin_bind_1 PF00187.19 CBY18304.1 - 0.13 12.7 23.8 0.12 12.9 20.1 2.7 2 1 1 3 3 3 0 Chitin recognition protein PARP PF00644.20 CBY18306.1 - 2e-72 242.9 0.0 4.5e-72 241.7 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CBY18306.1 - 2.4e-38 131.3 4.5 4.5e-38 130.4 4.5 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 CBY18306.1 - 4.2e-38 130.1 8.2 5e-19 68.9 1.3 3.4 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.15 CBY18306.1 - 2e-18 66.2 1.8 1.1e-17 63.8 0.7 2.7 2 0 0 2 2 2 1 WGR domain PADR1 PF08063.12 CBY18306.1 - 3.6e-17 61.9 0.3 9.3e-17 60.6 0.3 1.8 1 0 0 1 1 1 1 PADR1 (NUC008) domain BRCT PF00533.26 CBY18306.1 - 6.2e-05 23.3 0.2 0.0002 21.6 0.2 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBY18306.1 - 0.0072 16.7 0.2 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Filament PF00038.21 CBY18307.1 - 3.3e-14 53.2 72.2 2.3e-11 43.9 72.2 2.3 1 1 0 1 1 1 1 Intermediate filament protein DUF4472 PF14739.6 CBY18307.1 - 0.024 15.4 10.7 0.024 15.4 10.7 5.5 1 1 4 6 6 6 0 Domain of unknown function (DUF4472) Pkinase PF00069.25 CBY18308.1 - 1.1e-71 241.3 0.0 2.7e-71 240.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18308.1 - 4.5e-44 150.7 0.0 7.4e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBY18308.1 - 3.5e-10 40.3 0.3 1.2e-08 35.4 0.0 2.6 2 1 0 2 2 2 1 PH domain Kinase-like PF14531.6 CBY18308.1 - 1.2e-05 24.7 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CBY18308.1 - 0.0048 17.6 2.3 0.0099 16.6 2.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CBY18308.1 - 0.04 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Hid1 PF12722.7 CBY18309.1 - 0.011 13.9 10.6 0.013 13.6 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 CBY18309.1 - 5.6 7.5 11.2 7.2 7.1 11.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CCDC84 PF14968.6 CBY18309.1 - 9.3 5.8 10.7 13 5.3 10.7 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 Pkinase PF00069.25 CBY18310.1 - 3.1e-39 134.9 0.0 7.1e-39 133.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18310.1 - 1.3e-22 80.4 0.0 5.4e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase SRP72 PF08492.12 CBY18310.1 - 2e-09 37.7 12.6 4.9e-09 36.5 12.6 1.7 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_19 PF14559.6 CBY18310.1 - 9.1e-09 35.7 8.6 0.0025 18.3 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY18310.1 - 2.1e-05 25.0 5.0 0.14 13.1 0.1 5.5 7 1 0 7 7 6 1 Tetratricopeptide repeat Kinase-like PF14531.6 CBY18310.1 - 0.00072 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CBY18310.1 - 0.0036 18.0 2.3 0.013 16.2 2.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain TPR_12 PF13424.6 CBY18310.1 - 0.0056 16.9 7.6 0.011 16.0 0.1 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY18310.1 - 0.023 14.8 4.3 47 4.4 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat APH PF01636.23 CBY18310.1 - 0.1 12.5 0.1 0.6 10.0 0.1 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family HK_sensor PF16750.5 CBY18310.1 - 0.13 12.6 0.3 0.48 10.7 0.2 2.1 1 1 0 1 1 1 0 Sensor domain of 2-component histidine kinase TPR_8 PF13181.6 CBY18310.1 - 0.96 9.8 7.7 19 5.8 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Macoilin PF09726.9 CBY18311.1 - 1.2 7.7 11.4 1.5 7.3 11.4 1.3 1 0 0 1 1 1 0 Macoilin family SOBP PF15279.6 CBY18311.1 - 2.6 8.6 11.0 3.2 8.3 11.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RAP1 PF07218.11 CBY18311.1 - 2.7 6.2 11.2 3 6.0 11.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SRP_TPR_like PF17004.5 CBY18312.1 - 5.7e-20 71.5 3.0 5.7e-20 71.5 3.0 3.7 4 0 0 4 4 4 1 Putative TPR-like repeat TPR_19 PF14559.6 CBY18312.1 - 6.7e-11 42.6 18.3 0.0025 18.3 0.2 7.3 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY18312.1 - 1.4e-10 41.1 11.5 0.086 13.7 0.2 8.0 8 2 1 9 9 8 2 Tetratricopeptide repeat SRP72 PF08492.12 CBY18312.1 - 2.2e-09 37.6 10.9 2.2e-09 37.6 10.9 2.7 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_2 PF07719.17 CBY18312.1 - 8.2e-08 31.8 20.0 0.03 14.4 0.4 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY18312.1 - 1.6e-07 31.5 18.6 0.011 16.0 0.1 6.5 7 1 1 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY18312.1 - 1.7e-06 28.2 4.0 1.7e-06 28.2 4.0 5.4 6 2 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CBY18312.1 - 6.9e-05 22.9 1.9 3.8 7.7 0.0 5.7 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY18312.1 - 0.00013 22.3 12.8 0.44 11.3 0.0 6.8 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY18312.1 - 0.001 19.7 4.0 5.1 7.8 0.1 6.1 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY18312.1 - 0.0016 18.2 15.1 0.48 10.3 0.2 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat ChaB PF06150.12 CBY18312.1 - 0.0022 18.5 0.3 2.4 8.8 0.1 3.2 2 0 0 2 2 2 1 ChaB TPR_11 PF13414.6 CBY18312.1 - 0.0025 17.5 6.0 8.3 6.2 0.0 5.8 5 0 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 CBY18312.1 - 0.011 15.7 7.0 0.13 12.4 0.1 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat PPR PF01535.20 CBY18312.1 - 0.012 15.8 0.3 21 5.7 0.0 4.8 5 0 0 5 5 5 0 PPR repeat HK_sensor PF16750.5 CBY18312.1 - 0.1 12.9 0.3 0.46 10.8 0.2 2.2 1 1 0 1 1 1 0 Sensor domain of 2-component histidine kinase Alkyl_sulf_dimr PF14863.6 CBY18312.1 - 0.29 11.6 4.5 4.5 7.7 0.4 3.4 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_8 PF13181.6 CBY18312.1 - 0.37 11.1 22.3 7.2 7.1 0.1 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY18312.1 - 0.42 10.5 11.2 1.2 9.1 0.7 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 CBY18313.1 - 6e-10 39.1 20.0 4.3e-05 23.8 1.1 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY18313.1 - 3.8e-08 33.5 19.3 0.0025 18.5 1.3 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY18313.1 - 1.2e-05 25.4 22.1 0.0019 18.5 1.3 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY18313.1 - 0.027 14.8 17.8 0.087 13.1 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CBY18313.1 - 0.043 14.5 14.0 0.45 11.2 1.6 4.0 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_6 PF18450.1 CBY18313.1 - 0.047 13.4 0.4 0.047 13.4 0.4 2.6 2 0 0 2 2 2 0 Zinc Finger domain zf-met PF12874.7 CBY18313.1 - 0.16 12.4 9.2 0.16 12.4 0.9 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 CBY18313.1 - 4.2 7.3 17.1 3.4 7.6 0.6 4.0 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_4 PF07975.12 CBY18313.1 - 8.8 6.7 10.6 27 5.1 2.9 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain GST_C_3 PF14497.6 CBY18314.1 - 3e-16 59.4 0.0 6.3e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY18314.1 - 2.3e-10 40.7 0.0 4.7e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY18314.1 - 3.6e-08 33.5 0.0 6.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY18314.1 - 0.00061 19.8 0.1 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CBY18314.1 - 0.047 14.4 0.0 0.27 12.0 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain DUF3361 PF11841.8 CBY18315.1 - 0.043 13.7 1.8 0.25 11.3 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) FAST_1 PF06743.15 CBY18315.1 - 0.31 11.0 2.7 7.2 6.6 0.2 3.0 2 1 1 3 3 3 0 FAST kinase-like protein, subdomain 1 GPCR_chapero_1 PF11904.8 CBY18316.1 - 1.9e-70 237.8 0.2 2.7e-70 237.3 0.2 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_4 PF13637.6 CBY18316.1 - 1.1e-11 45.0 0.0 3.2e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY18316.1 - 1.4e-11 44.8 0.0 6.7e-09 36.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY18316.1 - 1.4e-10 41.2 0.0 9.5e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CBY18316.1 - 7.9e-10 38.8 0.1 9e-09 35.4 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY18316.1 - 1.6e-09 37.2 0.0 3.4e-05 23.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Phenol_hyd_sub PF06099.11 CBY18316.1 - 0.081 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Phenol hydroxylase subunit FYVE PF01363.21 CBY18318.1 - 6.2e-18 64.7 10.4 1.2e-17 63.8 10.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.19 CBY18318.1 - 2.2e-17 63.3 0.5 5.1e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 RUN domain FYVE_2 PF02318.16 CBY18318.1 - 0.01 16.0 7.1 0.01 16.0 7.1 4.1 2 1 3 6 6 6 0 FYVE-type zinc finger ADK_lid PF05191.14 CBY18318.1 - 0.039 13.9 0.8 0.039 13.9 0.8 1.9 1 1 1 2 2 2 0 Adenylate kinase, active site lid DUF4688 PF15752.5 CBY18318.1 - 0.07 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) DASH_Hsk3 PF08227.11 CBY18318.1 - 0.33 11.3 8.5 1.2 9.6 0.3 4.0 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like zf-RING_5 PF14634.6 CBY18318.1 - 2.2 8.3 12.0 3.7 7.6 12.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain CDC73_N PF16050.5 CBY18319.1 - 3.6e-88 295.7 3.1 5.9e-88 295.0 3.1 1.3 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 CBY18319.1 - 2.3e-44 150.8 3.8 7.1e-44 149.3 2.1 2.5 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal DS PF01916.17 CBY18320.1 - 1.4e-122 408.5 0.0 1.6e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase PTE PF02126.18 CBY18322.1 - 2.1e-56 191.5 0.0 2.6e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family DUF4434 PF14488.6 CBY18322.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) Aida_N PF08910.10 CBY18323.1 - 0.29 11.6 9.2 5.7 7.4 0.2 3.6 3 1 0 3 3 3 0 Aida N-terminus DUF883 PF05957.13 CBY18323.1 - 8.9 7.0 10.5 2.9 8.5 0.3 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ThiF PF00899.21 CBY18324.1 - 2.2e-16 60.0 0.0 2.6e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CBY18325.1 - 7e-90 301.3 0.6 1.7e-89 300.1 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 CBY18325.1 - 2.5e-79 266.1 0.0 1.2e-76 257.3 0.0 2.1 2 0 0 2 2 2 2 ThiF family E1_UFD PF09358.10 CBY18325.1 - 2.5e-30 105.0 0.2 1.3e-29 102.7 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin fold domain E1_4HB PF16191.5 CBY18325.1 - 1.3e-15 57.3 1.0 5.1e-15 55.4 0.2 2.6 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle Pyr_redox PF00070.27 CBY18325.1 - 0.12 12.9 0.0 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.28 CBY18326.1 - 9.9e-91 305.1 0.0 1.3e-90 304.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY18326.1 - 9e-14 51.8 0.0 1.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY18326.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CBY18326.1 - 0.022 13.6 0.1 0.055 12.3 0.0 1.7 2 1 0 2 2 2 0 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 CBY18326.1 - 0.051 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ras PF00071.22 CBY18327.1 - 1.5e-28 99.4 0.2 2e-28 99.0 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY18327.1 - 2.8e-21 76.0 0.1 4.2e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY18327.1 - 2.5e-13 49.9 0.0 4.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DnaJ PF00226.31 CBY18327.1 - 1.7e-10 40.8 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain GTP_EFTU PF00009.27 CBY18327.1 - 4.5e-05 23.1 0.1 0.00045 19.8 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY18327.1 - 9e-05 22.4 0.1 0.043 13.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBY18327.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MnmE_helical PF12631.7 CBY18327.1 - 0.0083 16.3 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 MnmE helical domain FeoB_N PF02421.18 CBY18327.1 - 0.072 12.6 0.0 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DnaJ PF00226.31 CBY18328.1 - 0.0019 18.3 0.3 0.023 14.8 0.1 2.5 2 0 0 2 2 2 1 DnaJ domain Erythro_esteras PF05139.14 CBY18328.1 - 0.007 16.2 0.3 0.0085 15.9 0.3 1.1 1 0 0 1 1 1 1 Erythromycin esterase SpecificRecomb PF10136.9 CBY18328.1 - 0.1 10.9 1.5 0.12 10.6 1.5 1.0 1 0 0 1 1 1 0 Site-specific recombinase DUF1664 PF07889.12 CBY18328.1 - 1.1 9.4 4.0 1.3 9.1 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_23 PF13476.6 CBY18328.1 - 2.4 8.6 10.0 3.1 8.3 10.0 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 CBY18328.1 - 3.3 7.9 7.8 5.3 7.2 7.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IP_trans PF02121.18 CBY18329.1 - 5.5e-96 320.9 4.1 1e-95 320.0 4.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DDHD PF02862.17 CBY18329.1 - 8.8e-12 45.7 0.0 2.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 DDHD domain LNS2 PF08235.13 CBY18329.1 - 6.5e-05 22.5 0.0 0.00094 18.7 0.0 2.2 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Ig_mannosidase PF17753.1 CBY18329.1 - 0.021 14.5 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Ig-fold domain MFS_2 PF13347.6 CBY18330.1 - 0.0057 15.3 0.0 0.0087 14.7 0.0 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein DUF1345 PF07077.11 CBY18330.1 - 0.011 15.5 0.1 0.016 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF2207 PF09972.9 CBY18330.1 - 0.075 11.8 0.1 0.085 11.6 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.8 CBY18330.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) FUSC PF04632.12 CBY18330.1 - 0.17 10.4 2.8 0.25 9.9 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fer4_5 PF12801.7 CBY18330.1 - 0.23 11.4 0.3 0.23 11.4 0.3 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Orf78 PF06024.12 CBY18330.1 - 0.83 10.0 3.4 0.44 10.9 0.5 2.1 2 0 0 2 2 2 0 Orf78 (ac78) IFRD PF05004.13 CBY18331.1 - 1.2e-30 106.7 2.3 1.7e-30 106.2 2.3 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 CBY18331.1 - 0.001 19.6 1.9 0.0032 18.0 1.9 1.9 1 0 0 1 1 1 1 Interferon-related protein conserved region KH_1 PF00013.29 CBY18332.1 - 3.2e-38 129.4 15.3 7.2e-14 51.4 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CBY18332.1 - 8e-11 41.6 10.2 0.0015 18.3 0.6 3.4 3 1 0 3 3 3 3 KH domain KH_5 PF13184.6 CBY18332.1 - 4.5e-07 29.8 7.0 0.027 14.5 0.3 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.6 CBY18332.1 - 8.8e-06 25.5 12.2 0.011 15.5 0.1 4.2 3 1 1 4 4 4 2 KH domain MOEP19 PF16005.5 CBY18332.1 - 0.12 12.3 0.3 2.8 8.0 0.0 2.7 3 0 0 3 3 3 0 KH-like RNA-binding domain Tubulin PF00091.25 CBY18333.1 - 4.1e-68 229.5 0.0 5.4e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY18333.1 - 1.9e-47 160.6 0.0 3.1e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY18333.1 - 0.0017 18.1 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Aminotran_5 PF00266.19 CBY18335.1 - 4.6e-51 173.9 0.0 5.4e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CBY18335.1 - 1.1e-05 24.1 0.0 1.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CBY18335.1 - 0.0047 16.1 0.0 0.074 12.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II CoA_binding_2 PF13380.6 CBY18335.1 - 0.085 13.4 0.0 0.29 11.7 0.1 1.7 2 0 0 2 2 2 0 CoA binding domain Glycogen_syn PF05693.13 CBY18336.1 - 2e-154 515.6 0.0 2.3e-154 515.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CBY18336.1 - 4.9e-09 36.0 0.0 0.00033 20.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBY18336.1 - 1.5e-06 28.7 0.0 0.0086 16.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Imm68 PF15583.6 CBY18336.1 - 0.043 14.0 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 68 ArnB_C PF18677.1 CBY18336.1 - 0.21 11.7 1.6 5.2 7.2 0.0 2.7 3 0 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain RVT_1 PF00078.27 CBY18337.1 - 2.9e-06 27.0 0.4 0.015 14.8 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 CBY18337.1 - 0.01 15.5 0.2 0.024 14.3 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Paf67 PF10255.9 CBY18339.1 - 1.1e-135 452.7 8.6 1.8e-135 452.1 8.6 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_12 PF13424.6 CBY18339.1 - 0.013 15.8 0.4 0.033 14.5 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CBY18339.1 - 0.015 15.3 2.7 0.08 13.0 0.4 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 CBY18339.1 - 0.018 15.1 1.0 0.44 10.8 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2428 PF10350.9 CBY18339.1 - 0.023 13.9 0.2 1.5 8.0 0.1 2.3 1 1 1 2 2 2 0 Putative death-receptor fusion protein (DUF2428) TPR_6 PF13174.6 CBY18339.1 - 0.032 14.9 0.8 2.6 8.9 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Ca_bind_SSO6904 PF18249.1 CBY18339.1 - 0.051 13.9 0.4 1.7 9.1 0.0 2.9 2 0 0 2 2 2 0 Calcium binding protein SSO6904 WIYLD PF10440.9 CBY18339.1 - 0.12 12.2 3.1 0.12 12.2 0.4 2.4 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain TPR_1 PF00515.28 CBY18339.1 - 0.33 10.9 1.9 4.1 7.4 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Na_Pi_cotrans PF02690.15 CBY18340.1 - 2e-31 108.9 25.0 1.5e-18 67.2 6.3 2.9 2 1 0 2 2 2 2 Na+/Pi-cotransporter AOX PF01786.17 CBY18340.1 - 0.17 11.4 0.5 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Alternative oxidase Sigma_reg_N PF13800.6 CBY18340.1 - 0.41 11.0 0.1 0.41 11.0 0.1 4.4 5 0 0 5 5 5 0 Sigma factor regulator N-terminal ECH_1 PF00378.20 CBY18342.1 - 1.1e-37 129.7 0.0 1.4e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY18342.1 - 9.8e-15 54.9 0.0 1.2e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DJ-1_PfpI PF01965.24 CBY18342.1 - 0.048 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family TFIID_20kDa PF03847.13 CBY18342.1 - 0.16 12.5 0.1 20 5.8 0.0 2.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A DUF4456 PF14644.6 CBY18343.1 - 9.6e-24 84.2 0.5 9.6e-24 84.2 0.5 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4456) TetR_C_24 PF17932.1 CBY18343.1 - 0.04 14.2 1.8 2.5 8.4 0.1 3.9 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF2564 PF10819.8 CBY18343.1 - 1.3 9.5 7.9 18 5.8 0.6 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) Phospholip_A2_1 PF00068.19 CBY18344.1 - 2.5e-08 34.4 8.0 5.6e-08 33.2 8.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 ANF_receptor PF01094.28 CBY18345.1 - 3.6e-13 49.4 0.3 1.2e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region DUF1281_C PF18406.1 CBY18345.1 - 0.073 12.8 0.2 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Ferredoxin-like domain in Api92-like protein PTR2 PF00854.21 CBY18345.1 - 0.14 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 POT family GAGA_bind PF06217.12 CBY18346.1 - 2.1 8.6 7.9 4.5 7.5 7.9 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Golgin_A5 PF09787.9 CBY18347.1 - 8.9 5.7 60.8 0.25 10.8 3.4 4.3 1 1 3 4 4 4 0 Golgin subfamily A member 5 Gal-3-0_sulfotr PF06990.11 CBY18348.1 - 6.3e-35 120.8 0.3 7e-34 117.4 0.3 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY18348.1 - 1.9e-05 24.7 3.6 5.3e-05 23.3 0.5 3.1 2 1 0 2 2 2 1 Sulfotransferase family Pet100 PF09803.9 CBY18348.1 - 0.46 11.0 3.1 0.56 10.8 0.3 2.6 2 0 0 2 2 2 0 Pet100 Sugar_tr PF00083.24 CBY18349.1 - 6.6e-113 377.9 21.3 7.5e-113 377.8 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY18349.1 - 6.8e-31 107.5 40.9 1.4e-24 86.7 9.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CDV3 PF15359.6 CBY18350.1 - 6 7.4 11.4 0.75 10.3 6.5 2.0 2 1 0 2 2 2 0 Carnitine deficiency-associated protein 3 CBFB_NFYA PF02045.15 CBY18352.1 - 1.4e-27 96.1 3.8 4.4e-27 94.5 3.8 2.0 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B YlzJ PF14035.6 CBY18352.1 - 0.21 11.8 3.1 1.9 8.8 0.2 3.3 3 0 0 3 3 3 0 YlzJ-like protein DUF846 PF05832.12 CBY18353.1 - 8.8e-46 155.4 1.7 1.1e-45 155.1 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) 2-oxoacid_dh PF00198.23 CBY18354.1 - 6.2e-77 258.2 0.4 8.1e-77 257.8 0.4 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DEAD PF00270.29 CBY18354.1 - 1.6e-43 148.5 0.1 2.2e-43 148.0 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Biotin_lipoyl PF00364.22 CBY18354.1 - 1e-21 76.5 5.6 3.6e-11 42.7 0.3 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 CBY18354.1 - 1.4e-10 41.3 0.3 1.4e-10 41.3 0.3 1.8 2 0 0 2 2 2 1 e3 binding domain ResIII PF04851.15 CBY18354.1 - 2e-08 34.4 0.0 3.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBY18354.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase cNMP_binding PF00027.29 CBY18355.1 - 2.3e-37 126.9 0.2 1.1e-18 67.1 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CBY18355.1 - 2.8e-09 36.5 0.1 7.2e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 CBY18355.1 - 0.00057 19.5 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Cupin_2 PF07883.11 CBY18355.1 - 0.14 11.9 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Cupin domain MitoNEET_N PF10660.9 CBY18355.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus CMS1 PF14617.6 CBY18356.1 - 1.2e-26 93.5 11.9 7.1e-26 91.1 0.7 2.0 1 1 1 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit XkdW PF09636.10 CBY18356.1 - 0.064 13.3 6.1 0.12 12.4 2.0 2.3 2 0 0 2 2 2 0 XkdW protein PolyA_pol_arg_C PF12626.7 CBY18356.1 - 0.58 10.2 5.9 1.2 9.2 5.9 1.5 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus TMEM208_SND2 PF05620.11 CBY18356.1 - 2.4 7.9 4.3 3.7 7.3 4.3 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 CENP-B_N PF04218.13 CBY18358.1 - 1.2e-07 31.3 8.4 0.0015 18.1 0.4 3.3 3 0 0 3 3 3 2 CENP-B N-terminal DNA-binding domain HTH_24 PF13412.6 CBY18358.1 - 0.0025 17.3 0.0 5.3 6.7 0.0 3.7 3 1 0 3 3 3 2 Winged helix-turn-helix DNA-binding PET PF06297.14 CBY18358.1 - 0.054 13.8 1.5 0.11 12.8 1.5 1.5 1 0 0 1 1 1 0 PET Domain CENP-B_N PF04218.13 CBY18359.1 - 6e-08 32.2 5.0 0.0019 17.8 0.4 3.3 3 0 0 3 3 3 2 CENP-B N-terminal DNA-binding domain Trypan_PARP PF05887.11 CBY18359.1 - 0.031 14.3 2.1 0.031 14.3 2.1 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) AAA_assoc_2 PF16193.5 CBY18361.1 - 4.7 7.6 7.7 2.4 8.6 0.5 3.8 2 1 1 3 3 3 0 AAA C-terminal domain Arm-DNA-bind_1 PF09003.10 CBY18361.1 - 6.1 7.1 11.2 0.57 10.4 0.4 4.0 4 0 0 4 4 4 0 Bacteriophage lambda integrase, Arm DNA-binding domain START PF01852.19 CBY18362.1 - 0.0003 20.3 0.3 0.00046 19.7 0.3 1.2 1 0 0 1 1 1 1 START domain Mt_ATP-synt_D PF05873.12 CBY18362.1 - 0.066 13.1 0.3 0.7 9.7 0.2 2.2 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF2282 PF10048.9 CBY18362.1 - 0.07 13.1 0.4 0.22 11.5 0.4 1.8 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) CheF-arch PF04283.12 CBY18362.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Chemotaxis signal transduction system protein F from archaea Aldedh PF00171.22 CBY18363.1 - 9.2e-169 561.8 0.6 2.3e-168 560.5 0.0 1.9 2 0 0 2 2 2 1 Aldehyde dehydrogenase family START PF01852.19 CBY18364.1 - 0.00026 20.5 0.2 0.00039 19.9 0.2 1.2 1 0 0 1 1 1 1 START domain DUF2282 PF10048.9 CBY18364.1 - 0.0042 17.0 0.4 0.013 15.5 0.4 1.8 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2282) Mt_ATP-synt_D PF05873.12 CBY18364.1 - 0.066 13.1 0.3 0.7 9.7 0.2 2.2 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) CheF-arch PF04283.12 CBY18364.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Chemotaxis signal transduction system protein F from archaea Aldedh PF00171.22 CBY18365.1 - 8.2e-179 594.9 0.0 9.2e-179 594.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CCDC53 PF10152.9 CBY18366.1 - 9.9e-05 22.8 0.1 0.00014 22.3 0.1 1.3 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Dynactin_p22 PF07426.11 CBY18366.1 - 0.029 14.2 0.4 0.49 10.2 0.0 2.0 1 1 1 2 2 2 0 Dynactin subunit p22 FlxA PF14282.6 CBY18366.1 - 0.047 13.7 0.0 0.082 12.9 0.0 1.4 1 1 0 1 1 1 0 FlxA-like protein XhlA PF10779.9 CBY18366.1 - 0.063 13.5 0.3 0.69 10.2 0.0 2.1 2 1 0 2 2 2 0 Haemolysin XhlA MtrG PF04210.13 CBY18366.1 - 0.16 11.8 0.1 0.38 10.6 0.0 1.6 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4533 PF15047.6 CBY18367.1 - 0.018 14.6 0.8 0.22 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) MAGE PF01454.19 CBY18367.1 - 0.059 13.1 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 MAGE family MIP PF00230.20 CBY18368.1 - 2.6e-19 69.8 3.1 4.2e-19 69.2 3.1 1.3 1 1 0 1 1 1 1 Major intrinsic protein EzrA PF06160.12 CBY18371.1 - 0.0017 16.6 8.2 0.0024 16.2 8.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA CLZ PF16526.5 CBY18371.1 - 0.018 15.4 3.6 0.05 14.0 3.6 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlxA PF14282.6 CBY18371.1 - 0.026 14.5 6.2 0.036 14.0 5.5 1.6 1 1 0 1 1 1 0 FlxA-like protein DUF2381 PF09544.10 CBY18371.1 - 0.076 12.5 1.0 0.12 11.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DUF4239 PF14023.6 CBY18371.1 - 0.1 12.3 1.6 0.14 11.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) HIP1_clath_bdg PF16515.5 CBY18371.1 - 0.15 12.6 7.0 0.3 11.7 7.0 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1840 PF08895.11 CBY18371.1 - 0.16 12.3 1.1 0.31 11.4 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF4349 PF14257.6 CBY18371.1 - 0.29 10.6 6.5 0.6 9.5 6.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) bZIP_1 PF00170.21 CBY18371.1 - 0.38 10.9 6.7 1.4 9.1 1.3 2.6 1 1 0 2 2 2 0 bZIP transcription factor VSG_B PF13206.6 CBY18371.1 - 0.44 9.8 4.8 0.55 9.4 4.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DivIC PF04977.15 CBY18371.1 - 0.98 9.2 5.9 1 9.2 0.6 2.6 2 0 0 2 2 2 0 Septum formation initiator AAA_30 PF13604.6 CBY18372.1 - 0.029 14.1 0.1 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain adh_short PF00106.25 CBY18374.1 - 1e-27 96.9 0.0 1.2e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY18374.1 - 1.9e-13 50.5 0.0 2.4e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY18374.1 - 0.00034 20.6 0.0 0.00045 20.2 0.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CBY18374.1 - 0.0022 17.9 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 CBY18374.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.21 CBY18374.1 - 0.13 11.6 2.2 6 6.2 0.0 2.2 2 0 0 2 2 2 0 ThiF family 7tm_1 PF00001.21 CBY18375.1 - 0.00018 20.9 0.1 0.0003 20.2 0.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Alfin PF12165.8 CBY18375.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Alfin DUF2781 PF10914.8 CBY18375.1 - 0.036 14.5 0.0 0.041 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) LMBR1 PF04791.16 CBY18375.1 - 0.041 12.8 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Connexin PF00029.19 CBY18376.1 - 2.5e-19 70.0 1.7 3.7e-19 69.4 1.7 1.2 1 0 0 1 1 1 1 Connexin Connexin PF00029.19 CBY18377.1 - 3.2e-23 82.7 0.2 3.6e-23 82.5 0.2 1.0 1 0 0 1 1 1 1 Connexin DUF2070 PF09843.9 CBY18378.1 - 0.38 9.0 6.7 0.45 8.7 6.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) bZIP_1 PF00170.21 CBY18379.1 - 9.8e-10 38.4 11.4 4.3e-09 36.3 11.4 2.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY18379.1 - 4.7e-07 29.8 11.5 4.7e-07 29.8 11.5 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY18379.1 - 0.019 15.5 3.2 0.019 15.5 3.2 3.3 3 0 0 3 3 3 0 bZIP Maf transcription factor zf-C2H2_jaz PF12171.8 CBY18380.1 - 2.2e-06 27.8 0.6 4.9e-06 26.7 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY18380.1 - 0.00086 19.6 0.3 0.0017 18.7 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CBY18380.1 - 0.0018 18.0 3.8 0.0058 16.4 3.8 1.9 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.7 CBY18380.1 - 0.0058 16.9 1.3 0.012 16.0 1.3 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) MRNIP PF15749.5 CBY18380.1 - 0.015 16.0 5.6 0.015 16.0 5.6 2.9 2 1 0 2 2 2 0 MRN-interacting protein Phe_ZIP PF08916.11 CBY18380.1 - 0.097 13.4 0.4 0.31 11.8 0.2 2.1 2 0 0 2 2 2 0 Phenylalanine zipper RNase_T PF00929.24 CBY18381.1 - 0.015 15.8 0.0 0.022 15.3 0.0 1.3 1 1 0 1 1 1 0 Exonuclease TPR_2 PF07719.17 CBY18382.1 - 6e-19 66.6 27.2 7.3e-07 28.8 0.5 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBY18382.1 - 2.2e-13 49.4 32.5 0.00011 21.9 0.2 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBY18382.1 - 6.6e-11 42.7 14.1 0.00033 21.2 1.8 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY18382.1 - 1.8e-09 37.7 15.4 2.1e-06 27.9 1.1 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY18382.1 - 4.7e-09 35.8 20.9 0.00032 20.3 1.7 6.0 4 2 2 6 6 6 4 TPR repeat TPR_14 PF13428.6 CBY18382.1 - 4.5e-08 33.3 9.3 0.02 15.7 0.0 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY18382.1 - 2.9e-06 27.7 13.9 0.055 14.0 2.6 5.6 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY18382.1 - 1.7e-05 24.7 21.0 0.0023 18.0 0.3 6.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY18382.1 - 1.8e-05 24.8 1.0 0.19 11.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY18382.1 - 3.5e-05 23.5 6.9 0.51 10.5 0.6 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY18382.1 - 0.00051 20.2 11.1 0.68 10.4 1.3 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY18382.1 - 0.13 12.9 10.5 1.3 9.8 0.1 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY18382.1 - 0.15 12.3 16.7 1.3 9.3 0.1 4.3 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 CBY18382.1 - 0.17 12.3 4.4 0.22 12.0 1.5 2.5 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation ArfGap PF01412.18 CBY18383.1 - 9.2e-32 109.6 0.8 2.2e-31 108.3 0.8 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.13 CBY18383.1 - 0.039 14.1 1.5 0.077 13.2 1.5 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger Ribosomal_L37ae PF01780.19 CBY18383.1 - 0.19 11.8 2.9 0.15 12.2 1.1 1.7 2 0 0 2 2 2 0 Ribosomal L37ae protein family eIF-1a PF01176.19 CBY18384.1 - 3.9e-19 68.2 0.0 5.5e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RabGAP-TBC PF00566.18 CBY18385.1 - 6.1e-36 124.1 0.6 9.5e-36 123.5 0.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 CBY18385.1 - 1.2e-10 41.9 0.0 2.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 CBY18385.1 - 0.00062 19.2 0.0 0.0049 16.3 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18385.1 - 0.054 12.8 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Rhodanese PF00581.20 CBY18386.1 - 3e-11 43.8 0.0 5.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain RabGAP-TBC PF00566.18 CBY18386.1 - 3.2e-09 36.8 0.9 4.8e-09 36.2 0.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase_Tyr PF07714.17 CBY18387.1 - 3.1e-88 295.4 0.0 4.6e-88 294.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY18387.1 - 5.5e-43 147.2 0.0 8.6e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gla PF00594.20 CBY18387.1 - 5.6e-17 61.7 6.6 1.1e-16 60.8 5.7 2.0 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain TMEM100 PF16311.5 CBY18387.1 - 0.0001 21.9 0.2 0.0002 20.9 0.2 1.4 1 0 0 1 1 1 1 Transmembrane protein 100 Haspin_kinase PF12330.8 CBY18387.1 - 0.011 14.8 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain LapA_dom PF06305.11 CBY18387.1 - 0.059 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Caskin-Pro-rich PF16907.5 CBY18387.1 - 0.064 13.8 1.6 0.16 12.5 1.6 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins BatD PF13584.6 CBY18387.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.6 CBY18387.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF5385 PF17359.2 CBY18387.1 - 0.11 12.0 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) EphA2_TM PF14575.6 CBY18387.1 - 0.11 13.3 0.1 0.11 13.3 0.1 2.3 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain IPK PF03770.16 CBY18388.1 - 3.8e-48 164.0 0.0 6e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase LCE PF14672.6 CBY18388.1 - 0.2 12.3 3.1 0.13 12.8 1.1 1.7 2 0 0 2 2 2 0 Late cornified envelope MitMem_reg PF13012.6 CBY18389.1 - 9.3e-06 26.0 0.3 1.2e-05 25.6 0.3 1.4 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CBY18389.1 - 0.00027 20.9 0.1 0.00062 19.7 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Sec3_C PF09763.9 CBY18390.1 - 1e-131 440.7 12.6 1.3e-131 440.3 12.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CBY18390.1 - 5.5e-22 77.7 0.5 1.4e-21 76.4 0.5 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Ribosomal_L22e PF01776.17 CBY18390.1 - 0.023 15.1 0.3 0.16 12.4 0.1 2.7 2 0 0 2 2 2 0 Ribosomal L22e protein family Baculo_PEP_C PF04513.12 CBY18390.1 - 0.039 14.0 1.6 0.19 11.7 1.6 2.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4349 PF14257.6 CBY18390.1 - 0.049 13.1 0.8 0.14 11.6 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HEAT PF02985.22 CBY18391.1 - 1.4e-19 68.5 8.7 0.0051 17.0 0.0 7.2 7 0 0 7 7 7 6 HEAT repeat HEAT_2 PF13646.6 CBY18391.1 - 4.6e-11 43.0 0.2 0.00014 22.2 0.0 5.4 3 2 2 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CBY18391.1 - 5.1e-05 23.8 1.5 0.13 12.8 0.1 4.8 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CBY18391.1 - 0.00071 19.7 3.9 0.049 13.7 2.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CBY18391.1 - 0.0022 18.4 1.1 0.92 10.1 0.0 4.6 6 0 0 6 6 6 1 HEAT-like repeat PHA_synth_III_E PF09712.10 CBY18394.1 - 0.013 14.6 0.2 0.025 13.7 0.2 1.4 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) UBN_AB PF14075.6 CBY18394.1 - 0.051 13.3 0.3 0.051 13.3 0.3 1.8 2 0 0 2 2 2 0 Ubinuclein conserved middle domain POX PF07526.11 CBY18394.1 - 0.092 13.3 0.3 0.23 12.0 0.3 1.7 1 0 0 1 1 1 0 Associated with HOX UBX PF00789.20 CBY18395.1 - 1.1e-14 54.4 0.0 2.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.25 CBY18396.1 - 5.1e-44 150.6 0.9 1.6e-43 149.0 0.9 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18396.1 - 1.7e-20 73.4 0.2 6.4e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBY18396.1 - 0.0004 19.5 0.8 0.0014 17.6 0.1 2.0 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CBY18396.1 - 0.58 9.7 0.0 0.58 9.7 0.0 3.8 3 1 1 4 4 4 0 RIO1 family GST_N PF02798.20 CBY18397.1 - 2.4e-15 56.7 0.0 5e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY18397.1 - 1.4e-13 51.0 0.0 2.6e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY18397.1 - 4.7e-08 33.2 0.0 1.2e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CBY18397.1 - 1e-07 32.1 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBY18397.1 - 0.00029 21.0 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-NOSIP PF15906.5 CBY18397.1 - 0.041 14.0 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Ion_trans PF00520.31 CBY18398.1 - 4.7e-19 68.6 7.7 6.7e-19 68.1 7.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY18398.1 - 8.3e-10 38.5 2.4 8.3e-10 38.5 2.4 2.0 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 CBY18398.1 - 9.8e-09 35.2 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EF_assoc_1 PF08355.12 CBY18398.1 - 0.2 11.3 0.1 6.7 6.4 0.1 2.4 2 0 0 2 2 2 0 EF hand associated zf-C2H2 PF00096.26 CBY18400.1 - 5e-16 58.2 34.8 3.4e-06 27.2 0.5 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY18400.1 - 7.6e-15 54.6 30.7 1e-06 28.9 2.8 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY18400.1 - 3.4e-11 43.0 36.7 0.00038 21.1 0.3 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 CBY18400.1 - 1.1e-07 31.9 30.4 0.11 13.0 1.5 5.7 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY18400.1 - 9.5e-07 29.0 24.8 0.00045 20.4 0.4 5.6 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CBY18400.1 - 2.7e-06 27.0 22.6 0.0029 17.3 0.1 5.0 4 0 0 4 4 4 2 C2H2-type zinc-finger domain GAGA PF09237.11 CBY18400.1 - 0.0025 17.6 1.0 0.018 14.8 0.0 2.6 1 1 1 2 2 2 1 GAGA factor zf-C2H2_11 PF16622.5 CBY18400.1 - 0.023 14.4 0.9 0.023 14.4 0.9 4.0 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY18400.1 - 0.036 14.1 2.1 0.036 14.1 2.1 4.9 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_7 PF15269.6 CBY18400.1 - 0.09 12.9 6.3 21 5.3 0.1 3.8 1 1 2 3 3 3 0 Zinc-finger zf-BED PF02892.15 CBY18400.1 - 2.2 8.4 13.4 1.2 9.2 0.6 3.2 1 1 2 3 3 3 0 BED zinc finger Presenilin PF01080.17 CBY18400.1 - 3.2 6.4 6.2 4.3 6.0 6.2 1.1 1 0 0 1 1 1 0 Presenilin Na_H_Exchanger PF00999.21 CBY18401.1 - 3.4e-56 190.7 31.2 4.1e-56 190.4 31.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MRP-S28 PF10213.9 CBY18401.1 - 0.1 13.0 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Trypsin PF00089.26 CBY18403.1 - 1.6e-55 188.3 0.3 1.6e-55 188.3 0.3 2.0 3 0 0 3 3 3 1 Trypsin Trypsin_2 PF13365.6 CBY18403.1 - 0.0094 16.9 0.0 0.026 15.4 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain UPF0242 PF06785.11 CBY18404.1 - 0.00095 19.3 6.5 0.00095 19.3 6.5 3.3 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Endotoxin_N PF03945.14 CBY18404.1 - 0.0032 17.2 0.8 0.0074 16.0 0.8 1.6 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Profilin PF00235.19 CBY18406.1 - 3e-10 40.5 0.0 3.3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Profilin DUF525 PF04379.14 CBY18407.1 - 8.6e-24 83.6 0.0 1.4e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 ApaG domain SMI1_KNR4 PF09346.10 CBY18407.1 - 0.00061 20.2 0.0 0.00099 19.5 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) CTP_transf_like PF01467.26 CBY18408.1 - 2.8e-19 69.7 0.0 3e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like CTP_transf_like PF01467.26 CBY18409.1 - 2.5e-05 24.5 0.0 3.6e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase-like O-FucT PF10250.9 CBY18410.1 - 9.7e-08 32.1 0.0 2.3e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Presenilin PF01080.17 CBY18411.1 - 0.008 15.0 6.1 0.0086 14.9 6.1 1.1 1 0 0 1 1 1 1 Presenilin PARM PF17061.5 CBY18411.1 - 0.0081 16.3 21.0 0.009 16.2 21.0 1.1 1 0 0 1 1 1 1 PARM Zip PF02535.22 CBY18411.1 - 0.017 14.3 0.6 0.019 14.2 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Endomucin PF07010.12 CBY18411.1 - 0.019 14.9 19.5 0.023 14.7 19.5 1.1 1 0 0 1 1 1 0 Endomucin MDFI PF15316.6 CBY18411.1 - 0.064 13.3 6.1 0.081 13.0 6.1 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Raftlin PF15250.6 CBY18411.1 - 0.07 11.9 5.8 0.076 11.8 5.8 1.0 1 0 0 1 1 1 0 Raftlin ABC2_membrane_3 PF12698.7 CBY18411.1 - 0.14 11.2 8.1 0.19 10.8 8.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Ndc1_Nup PF09531.10 CBY18411.1 - 0.41 9.3 11.3 0.48 9.0 11.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.13 CBY18411.1 - 0.56 9.2 12.4 0.7 8.9 12.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.14 CBY18411.1 - 0.72 9.8 8.8 0.79 9.6 8.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RIFIN PF02009.16 CBY18411.1 - 0.81 9.5 8.6 0.86 9.4 8.6 1.1 1 0 0 1 1 1 0 Rifin TFIIA PF03153.13 CBY18411.1 - 1.2 9.1 15.6 1.4 8.8 15.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pannexin_like PF12534.8 CBY18411.1 - 1.3 8.0 10.0 1.7 7.7 10.0 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Plasmodium_Vir PF05795.11 CBY18411.1 - 2.6 7.3 7.7 3.1 7.1 7.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4400 PF14348.6 CBY18411.1 - 3.3 7.1 5.9 4.6 6.7 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) DUF3801 PF12687.7 CBY18411.1 - 3.4 7.7 12.7 4.2 7.4 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) MCLC PF05934.11 CBY18411.1 - 5.6 5.6 13.0 6.5 5.4 13.0 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF1387 PF07139.11 CBY18411.1 - 7.6 6.2 14.4 9.2 5.9 14.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TPH PF13868.6 CBY18413.1 - 1.3e-20 73.2 23.8 1.3e-20 73.2 23.8 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RITA PF17066.5 CBY18413.1 - 0.025 14.2 1.0 0.048 13.2 0.1 1.9 2 1 1 3 3 3 0 RBPJ-interacting and tubulin associated protein TPH PF13868.6 CBY18414.1 - 1.4e-27 96.1 57.0 1.6e-27 96.0 57.0 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Peptidase_S46 PF10459.9 CBY18414.1 - 0.36 9.4 21.1 0.45 9.1 21.1 1.1 1 0 0 1 1 1 0 Peptidase S46 LptF_LptG PF03739.14 CBY18414.1 - 3.8 6.3 8.3 4.2 6.1 8.3 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RE_Bpu10I PF09549.10 CBY18414.1 - 4.6 6.8 12.7 0.15 11.7 2.3 2.2 2 0 0 2 2 2 0 Bpu10I restriction endonuclease Endostatin PF06482.11 CBY18415.1 - 2.1e-93 313.3 0.5 2.6e-93 313.0 0.5 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Collagen PF01391.18 CBY18415.1 - 2.8e-50 167.9 187.2 1.8e-09 37.2 30.4 7.5 4 2 2 6 6 6 6 Collagen triple helix repeat (20 copies) Dicty_REP PF05086.12 CBY18415.1 - 0.019 13.0 6.5 0.025 12.6 6.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Chlam_PMP PF02415.17 CBY18416.1 - 0.059 13.9 0.0 0.33 11.5 0.0 2.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat bZIP_2 PF07716.15 CBY18416.1 - 0.062 13.4 1.5 0.24 11.5 1.5 2.0 1 0 0 1 1 1 0 Basic region leucine zipper Zona_pellucida PF00100.23 CBY18417.1 - 5.5e-24 85.4 7.7 6.2e-24 85.2 7.7 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Chlam_PMP PF02415.17 CBY18418.1 - 0.057 13.9 0.0 0.33 11.5 0.0 2.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SBF PF01758.16 CBY18419.1 - 2.3e-20 73.1 11.7 4.3e-20 72.2 11.7 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 CBY18419.1 - 0.0012 18.3 6.1 0.0016 17.9 6.1 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) UvrD-helicase PF00580.21 CBY18419.1 - 0.058 12.9 1.5 0.14 11.6 1.5 1.7 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Halogen_Hydrol PF10112.9 CBY18419.1 - 0.11 12.5 1.4 14 5.6 0.0 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LRR_8 PF13855.6 CBY18420.1 - 7.1e-23 80.1 19.6 3.6e-12 45.9 2.1 3.6 3 1 1 4 4 4 3 Leucine rich repeat zf-C2H2_4 PF13894.6 CBY18420.1 - 1.9e-13 50.0 52.7 0.0011 19.6 3.2 8.2 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY18420.1 - 8.8e-13 47.9 56.4 0.0026 18.1 3.3 8.0 9 0 0 9 9 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY18420.1 - 1.3e-05 25.4 2.3 1.3e-05 25.4 2.3 10.0 9 1 1 10 10 10 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 CBY18420.1 - 8.9e-05 22.8 23.0 0.22 11.9 0.2 5.7 5 1 0 5 5 5 2 C2H2 type zinc-finger (2 copies) LRR_4 PF12799.7 CBY18420.1 - 0.00039 20.7 9.1 0.0031 17.9 0.6 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY18420.1 - 0.0015 18.5 0.0 0.005 16.8 0.0 1.8 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) zf-C2H2_3rep PF18868.1 CBY18420.1 - 0.0041 17.8 24.2 0.0047 17.6 0.2 6.0 4 2 3 7 7 7 2 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 CBY18420.1 - 0.005 17.3 20.7 0.47 10.9 0.7 6.1 5 1 0 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 CBY18420.1 - 0.022 14.7 1.2 0.022 14.7 1.2 6.2 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 CBY18420.1 - 0.069 13.5 24.7 0.43 10.9 0.3 6.3 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding LRR_9 PF14580.6 CBY18420.1 - 0.088 12.3 1.6 1.1 8.8 1.0 2.5 2 1 0 2 2 2 0 Leucine-rich repeat zf-C2H2_11 PF16622.5 CBY18420.1 - 0.13 12.1 29.8 0.28 11.0 0.0 5.6 6 0 0 6 6 5 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY18420.1 - 0.14 12.2 44.0 0.31 11.1 2.8 6.9 7 0 0 7 7 6 0 C2H2-type zinc finger DUF1178 PF06676.11 CBY18420.1 - 0.23 11.8 9.4 0.21 11.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) zf-met PF12874.7 CBY18420.1 - 0.56 10.7 24.9 0.16 12.4 0.3 6.8 6 1 1 7 7 7 0 Zinc-finger of C2H2 type DZR PF12773.7 CBY18420.1 - 0.9 9.6 22.8 15 5.7 0.2 5.0 4 1 0 4 4 4 0 Double zinc ribbon DUF629 PF04780.12 CBY18420.1 - 0.97 7.9 15.7 0.14 10.7 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF629) PyrI_C PF02748.15 CBY18420.1 - 1.1 9.2 19.5 7.4 6.6 0.1 6.0 5 1 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 CBY18420.1 - 2.1 8.7 29.7 0.83 10.0 1.0 5.0 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 CBY18420.1 - 5.9 7.3 9.1 10 6.5 0.6 3.3 3 0 0 3 3 3 0 zinc-finger-containing domain BSD PF03909.17 CBY18421.1 - 5.1e-12 45.6 1.3 1.7e-11 44.0 1.3 1.9 1 0 0 1 1 1 1 BSD domain GPP34 PF05719.11 CBY18422.1 - 3.6e-57 193.7 1.9 5.2e-57 193.2 1.9 1.3 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Troponin PF00992.20 CBY18423.1 - 7.2e-19 68.4 33.2 2.3e-13 50.6 28.5 2.0 1 1 1 2 2 2 2 Troponin DUF4366 PF14283.6 CBY18423.1 - 0.028 14.5 4.5 0.047 13.7 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) VIT1 PF01988.19 CBY18423.1 - 0.5 10.2 3.1 0.84 9.5 3.1 1.3 1 0 0 1 1 1 0 VIT family ANAPC_CDC26 PF10471.9 CBY18423.1 - 3.7 8.4 14.6 1.9 9.4 1.4 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 RR_TM4-6 PF06459.12 CBY18423.1 - 6.5 6.5 15.9 9 6.0 15.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sugar_tr PF00083.24 CBY18424.1 - 6.5e-33 114.3 15.0 1.7e-23 83.2 0.4 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBY18424.1 - 2.4e-20 72.8 21.5 2.2e-12 46.6 10.2 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1440 PF07274.12 CBY18424.1 - 0.011 16.0 1.1 0.063 13.6 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1440) YidC_periplas PF14849.6 CBY18424.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 YidC periplasmic domain Ribonuc_2-5A PF06479.12 CBY18425.1 - 2e-11 44.2 0.3 2e-11 44.2 0.3 2.2 2 0 0 2 2 2 1 Ribonuclease 2-5A Peptidase_C1 PF00112.23 CBY18426.1 - 3.9e-84 282.1 1.9 5.7e-84 281.6 1.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY18426.1 - 5.4e-15 55.6 3.3 1e-14 54.7 3.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY18426.1 - 0.0011 17.9 0.3 1.1 8.0 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Meiosis_expr PF15163.6 CBY18426.1 - 0.059 14.0 5.2 0.27 11.9 0.0 3.2 3 0 0 3 3 3 0 Meiosis-expressed GDA1_CD39 PF01150.17 CBY18429.1 - 2.9e-63 214.0 0.0 3.7e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_C1 PF00112.23 CBY18430.1 - 2.4e-72 243.5 5.3 3.7e-72 243.0 5.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY18430.1 - 2.9e-12 46.8 4.3 5.5e-12 45.9 4.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY18430.1 - 9.1e-06 24.7 1.8 0.0025 16.6 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 CBY18430.1 - 0.00013 21.8 0.3 0.00033 20.5 0.3 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Sulfotransfer_2 PF03567.14 CBY18431.1 - 1.4e-15 57.9 0.1 2e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Adhesin_P1 PF03257.13 CBY18432.1 - 0.042 14.4 0.9 0.28 11.7 0.9 2.5 1 0 0 1 1 1 0 Mycoplasma adhesin P1 GKAP PF03359.13 CBY18434.1 - 6.1 6.3 11.7 10 5.6 11.7 1.3 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Endosulfine PF04667.17 CBY18435.1 - 7.2e-11 42.1 0.2 1.1e-10 41.5 0.2 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Myb_DNA-bind_4 PF13837.6 CBY18435.1 - 0.095 13.1 0.9 0.13 12.6 0.9 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DEAD PF00270.29 CBY18436.1 - 2e-43 148.2 0.0 1.3e-42 145.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY18436.1 - 5.4e-29 100.8 0.5 1.2e-28 99.6 0.5 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY18436.1 - 9.4e-07 29.0 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SUKH_5 PF14567.6 CBY18436.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall TRIC PF05197.13 CBY18436.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 TRIC channel Geminin PF07412.12 CBY18437.1 - 8.2e-05 22.4 15.9 0.00011 22.0 15.9 1.2 1 0 0 1 1 1 1 Geminin PA28_alpha PF02251.18 CBY18437.1 - 0.16 12.1 4.3 0.36 10.9 0.3 2.8 2 2 0 2 2 2 0 Proteasome activator pa28 alpha subunit LUC7 PF03194.15 CBY18437.1 - 0.24 11.0 12.5 0.28 10.8 12.5 1.1 1 0 0 1 1 1 0 LUC7 N_terminus UCH PF00443.29 CBY18438.1 - 3.4e-44 151.3 0.1 5.1e-44 150.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CBY18438.1 - 3.6e-21 74.7 0.0 9.3e-10 38.2 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 CBY18438.1 - 1.7e-18 66.2 1.6 2.3e-17 62.5 1.3 2.4 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 CBY18438.1 - 1.9e-17 63.3 1.4 2.5e-16 59.8 0.2 2.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CBY18438.1 - 9.8e-10 38.5 1.1 1.2e-07 31.6 0.1 3.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 CBY18438.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Pkinase PF00069.25 CBY18439.1 - 1.6e-68 231.0 0.0 1.9e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18439.1 - 9.7e-32 110.3 0.0 1.7e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY18439.1 - 0.0011 19.0 0.1 0.04 13.8 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY18439.1 - 0.011 14.7 0.0 0.038 12.9 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 CBY18441.1 - 1.8e-68 230.8 0.0 2.1e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18441.1 - 9.9e-32 110.2 0.0 1.7e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY18441.1 - 0.0011 19.0 0.1 0.04 13.8 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY18441.1 - 0.011 14.7 0.0 0.038 12.9 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain COX15-CtaA PF02628.15 CBY18442.1 - 1.1e-95 320.5 3.0 1.2e-95 320.3 3.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NADH-u_ox-rdase PF10785.9 CBY18442.1 - 0.17 12.6 1.8 1.4 9.7 0.0 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PX PF00787.24 CBY18443.1 - 8.9e-26 90.1 0.8 4.3e-25 87.9 0.1 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CBY18443.1 - 0.00013 21.6 17.8 0.00019 21.1 15.2 2.2 2 1 0 2 2 2 1 Vps5 C terminal like RhoGEF PF00621.20 CBY18443.1 - 0.021 15.1 3.7 1 9.6 0.3 2.8 2 0 0 2 2 2 0 RhoGEF domain DUF1878 PF08963.10 CBY18443.1 - 0.04 14.4 0.3 0.14 12.6 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) DUF3452 PF11934.8 CBY18443.1 - 0.064 12.8 1.0 0.59 9.7 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) DUF1192 PF06698.11 CBY18443.1 - 0.22 11.6 2.3 14 5.9 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) NEXCaM_BD PF16644.5 CBY18443.1 - 0.48 10.7 3.4 5.4 7.3 0.0 3.5 4 0 0 4 4 4 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Muted PF14942.6 CBY18443.1 - 0.63 10.4 12.1 0.081 13.3 4.0 2.8 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein DUF4407 PF14362.6 CBY18443.1 - 0.92 8.8 9.4 0.46 9.8 6.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CBY18443.1 - 1.9 9.0 16.8 80 3.8 13.9 3.4 2 1 0 2 2 2 0 Apg6 coiled-coil region TBCA PF02970.16 CBY18443.1 - 7.4 7.0 10.6 1.9 8.9 4.5 3.0 2 1 1 3 3 3 0 Tubulin binding cofactor A RIC3 PF15361.6 CBY18444.1 - 1.8e-07 31.6 0.3 1.8e-07 31.6 0.3 2.6 2 2 0 2 2 1 1 Resistance to inhibitors of cholinesterase homologue 3 Syndecan PF01034.20 CBY18444.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain GatB_Yqey PF02637.18 CBY18444.1 - 0.03 14.2 3.2 0.03 14.2 3.2 2.0 2 0 0 2 2 2 0 GatB domain PIN_8 PF18476.1 CBY18444.1 - 0.17 11.8 13.5 0.094 12.6 11.6 1.4 1 1 0 1 1 1 0 PIN like domain ABC2_membrane_3 PF12698.7 CBY18444.1 - 0.42 9.7 5.7 0.54 9.3 5.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein CorA PF01544.18 CBY18444.1 - 0.47 9.7 3.8 1.6 8.0 3.8 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SieB PF14163.6 CBY18444.1 - 0.76 9.3 2.3 13 5.3 0.1 2.3 1 1 1 2 2 2 0 Super-infection exclusion protein B LMBR1 PF04791.16 CBY18444.1 - 0.93 8.3 5.5 1.3 7.8 5.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Cwf_Cwc_15 PF04889.12 CBY18444.1 - 3.1 7.5 27.0 4.6 6.9 27.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HrpB7 PF09486.10 CBY18444.1 - 3.3 8.1 10.5 0.89 9.9 2.1 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lipoprotein_2 PF00921.17 CBY18444.1 - 7.5 6.0 19.0 0.24 10.9 9.6 2.0 2 0 0 2 2 2 0 Borrelia lipoprotein His_Phos_2 PF00328.22 CBY18445.1 - 3.4e-10 39.8 0.4 3.2e-07 30.1 0.1 3.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Guanylate_cyc_2 PF09778.9 CBY18445.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase His_Phos_2 PF00328.22 CBY18446.1 - 5.4e-10 39.2 5.0 4.4e-08 32.9 4.2 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) YARHG PF13308.6 CBY18446.1 - 0.00051 19.9 3.0 0.58 10.1 0.3 2.7 2 0 0 2 2 2 2 YARHG domain Aminotran_1_2 PF00155.21 CBY18447.1 - 5.3e-37 127.8 0.0 6.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CBY18447.1 - 0.12 10.8 0.0 0.36 9.3 0.0 1.7 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme PX PF00787.24 CBY18448.1 - 2.3e-13 50.1 0.1 4.5e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 PX domain LRR_4 PF12799.7 CBY18448.1 - 1.6e-08 34.7 16.4 3.5e-06 27.2 4.7 4.4 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY18448.1 - 2.6e-05 23.9 15.1 0.027 14.2 7.0 3.6 1 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CBY18448.1 - 0.00013 21.5 3.3 0.00013 21.5 3.3 2.4 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CBY18448.1 - 0.00046 20.0 5.0 0.19 11.8 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat SoDot-IcmSS PF16848.5 CBY18448.1 - 0.0042 17.1 1.4 0.0059 16.6 0.3 1.8 2 0 0 2 2 2 1 Substrate of the Dot/Icm secretion system, putative LRR_1 PF00560.33 CBY18448.1 - 0.022 15.2 8.7 25 6.0 1.8 5.4 4 1 0 4 4 4 0 Leucine Rich Repeat CENP-F_leu_zip PF10473.9 CBY18449.1 - 0.00041 20.4 7.5 0.0012 18.9 7.2 2.0 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 CBY18449.1 - 0.015 15.7 1.2 0.042 14.2 1.2 1.8 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Filament PF00038.21 CBY18449.1 - 0.042 13.4 12.3 0.027 14.1 5.7 2.2 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 CBY18449.1 - 0.19 11.9 8.7 0.29 11.3 7.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 CBY18449.1 - 0.2 12.1 2.2 1.1 9.7 0.7 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 CBY18449.1 - 0.2 11.7 9.4 0.41 10.7 9.4 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CEP209_CC5 PF16574.5 CBY18449.1 - 0.21 11.8 11.2 0.3 11.3 6.2 2.4 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 TMF_DNA_bd PF12329.8 CBY18449.1 - 0.24 11.4 9.6 0.031 14.3 4.4 2.3 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding MCC-bdg_PDZ PF10506.9 CBY18449.1 - 0.27 11.3 4.1 0.42 10.7 2.2 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1664 PF07889.12 CBY18449.1 - 0.37 10.8 6.2 0.37 10.8 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CdvA PF18822.1 CBY18449.1 - 0.48 10.3 10.8 0.83 9.5 2.2 3.4 3 0 0 3 3 3 0 CdvA-like coiled-coil domain DUF3450 PF11932.8 CBY18449.1 - 0.59 9.4 10.2 0.22 10.8 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 CBY18449.1 - 0.96 10.0 11.6 0.76 10.3 8.9 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DHR10 PF18595.1 CBY18449.1 - 1.4 9.0 9.0 3.2 7.8 8.7 1.9 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain PKcGMP_CC PF16808.5 CBY18449.1 - 1.8 8.5 4.3 12 5.9 4.3 2.4 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lebercilin PF15619.6 CBY18449.1 - 2 8.0 14.9 0.15 11.7 8.6 2.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 CBY18449.1 - 2.7 8.5 6.2 0.5 10.8 1.3 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB betaPIX_CC PF16523.5 CBY18449.1 - 3.7 7.4 6.1 0.75 9.7 0.2 2.3 1 1 0 2 2 2 0 betaPIX coiled coil SKA1 PF07160.12 CBY18450.1 - 2.2e-15 57.2 7.0 3e-15 56.7 7.0 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Ca_bind_SSO6904 PF18249.1 CBY18450.1 - 0.0012 19.1 3.1 0.0016 18.7 0.3 2.5 3 0 0 3 3 3 1 Calcium binding protein SSO6904 Spc110_C PF18520.1 CBY18450.1 - 0.22 11.2 1.8 0.27 10.9 0.2 2.0 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain LRR_8 PF13855.6 CBY18451.1 - 2.5e-21 75.2 6.2 1.1e-09 37.9 0.1 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBY18451.1 - 3.2e-11 43.3 5.0 0.00066 20.0 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY18451.1 - 2e-05 24.5 5.8 1.8 9.4 0.1 5.7 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 CBY18451.1 - 4.3e-05 23.2 3.4 0.57 10.4 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeat Mic1 PF07035.12 CBY18452.1 - 1.9e-19 69.9 0.2 2.9e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like RB_A PF01858.17 CBY18452.1 - 0.04 13.7 0.1 0.26 11.1 0.1 2.1 1 1 0 1 1 1 0 Retinoblastoma-associated protein A domain SelB-wing_2 PF09106.11 CBY18452.1 - 0.073 13.3 0.1 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Mic1 PF07035.12 CBY18454.1 - 5e-20 71.8 0.2 7.5e-20 71.2 0.2 1.2 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like RB_A PF01858.17 CBY18454.1 - 0.035 13.9 0.1 0.27 11.1 0.1 2.2 1 1 0 1 1 1 0 Retinoblastoma-associated protein A domain zf-C2H2_2 PF12756.7 CBY18456.1 - 9.8e-25 86.8 21.7 1.3e-18 67.2 4.8 4.3 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBY18456.1 - 0.00087 19.9 30.9 0.086 13.7 2.5 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-BED PF02892.15 CBY18456.1 - 0.002 18.1 21.0 0.54 10.3 0.2 4.9 5 0 0 5 5 5 3 BED zinc finger zf-C2H2_6 PF13912.6 CBY18456.1 - 0.019 15.0 1.9 0.019 15.0 1.9 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY18456.1 - 0.022 15.2 5.0 0.022 15.2 5.0 4.7 5 1 0 5 5 5 0 Zinc finger, C2H2 type SRP_TPR_like PF17004.5 CBY18456.1 - 0.029 14.4 0.9 0.15 12.1 0.1 2.6 3 0 0 3 3 3 0 Putative TPR-like repeat FOXP-CC PF16159.5 CBY18456.1 - 0.1 13.2 11.4 0.12 13.0 0.1 4.6 4 0 0 4 4 4 0 FOXP coiled-coil domain zf-Di19 PF05605.12 CBY18456.1 - 7.2 7.0 20.0 1.7 9.0 1.6 4.4 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding NPL4 PF05021.15 CBY18457.1 - 8.2e-77 258.6 0.0 1.1e-76 258.1 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CBY18457.1 - 1.3e-21 77.2 0.1 4.4e-21 75.6 0.1 1.8 1 1 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CBY18457.1 - 1.1e-16 61.0 0.1 3.7e-16 59.4 0.1 1.9 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 AAA_12 PF13087.6 CBY18458.1 - 6.2e-45 153.3 0.5 1.3e-44 152.2 0.4 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBY18458.1 - 3.9e-35 121.9 0.1 2.2e-16 60.5 0.1 2.5 1 1 1 2 2 2 2 AAA domain Dna2 PF08696.11 CBY18458.1 - 4.2e-34 118.2 0.0 4.5e-33 114.8 0.0 2.6 3 0 0 3 3 3 1 DNA replication factor Dna2 AAA_30 PF13604.6 CBY18458.1 - 1.7e-12 47.5 0.0 4.7e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBY18458.1 - 6.6e-10 39.5 0.1 3.5e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CBY18458.1 - 1e-08 35.2 0.0 0.0079 16.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PDDEXK_1 PF12705.7 CBY18458.1 - 3.6e-06 27.1 0.0 6.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Helicase_RecD PF05127.14 CBY18458.1 - 0.00035 20.5 0.0 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 CBY18458.1 - 0.00085 18.9 0.6 0.0022 17.6 0.4 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Thioredoxin_16 PF18569.1 CBY18458.1 - 0.022 14.9 0.2 0.086 13.0 0.1 2.1 2 0 0 2 2 1 0 Thioredoxin-like domain ResIII PF04851.15 CBY18458.1 - 0.029 14.4 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 CBY18458.1 - 0.043 13.2 0.1 0.15 11.5 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 CBY18458.1 - 0.055 13.4 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UvrD_C_2 PF13538.6 CBY18458.1 - 0.075 12.9 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 CBY18458.1 - 0.1 11.9 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mucin PF01456.17 CBY18459.1 - 0.14 12.2 26.3 0.24 11.4 26.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein XRCC4 PF06632.12 CBY18459.1 - 0.4 9.5 16.8 0.012 14.5 9.3 1.9 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Wbp11 PF09429.10 CBY18459.1 - 1 9.8 15.3 6.7 7.2 5.9 2.8 2 0 0 2 2 2 0 WW domain binding protein 11 LapA_dom PF06305.11 CBY18459.1 - 8.2 6.3 7.0 4.5 7.2 0.2 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ion_trans PF00520.31 CBY18461.1 - 3.9e-33 114.7 18.6 5e-33 114.4 18.6 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CBY18461.1 - 2.6e-11 42.8 13.1 4.6e-11 42.0 13.1 1.3 1 0 0 1 1 1 1 Polycystin cation channel Glutaredoxin2_C PF04399.13 CBY18461.1 - 0.26 11.1 3.3 6.5 6.6 0.1 2.6 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain Spore_III_AF PF09581.10 CBY18461.1 - 0.27 11.2 6.1 11 6.0 0.1 3.2 3 0 0 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) DUF1664 PF07889.12 CBY18462.1 - 1.2e-05 25.3 10.7 0.013 15.5 1.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) CALCOCO1 PF07888.11 CBY18462.1 - 0.031 13.2 10.7 0.039 12.8 10.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.12 CBY18462.1 - 0.032 14.9 7.5 0.12 13.0 0.8 2.8 2 1 1 3 3 3 0 SlyX Flagellin_C PF00700.21 CBY18462.1 - 0.032 14.6 2.1 0.032 14.6 2.1 2.3 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region AAA_13 PF13166.6 CBY18462.1 - 0.036 12.7 13.4 0.041 12.5 13.4 1.0 1 0 0 1 1 1 0 AAA domain CCDC32 PF14989.6 CBY18462.1 - 0.059 13.4 4.4 0.088 12.8 4.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing 32 DUF16 PF01519.16 CBY18462.1 - 0.094 13.2 13.7 0.47 11.0 9.5 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Bcr-Abl_Oligo PF09036.10 CBY18462.1 - 0.1 12.6 0.2 0.1 12.6 0.2 2.3 2 2 2 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain Fib_alpha PF08702.10 CBY18462.1 - 0.16 12.2 9.4 0.25 11.5 9.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF155 PF02582.14 CBY18462.1 - 0.18 11.9 4.1 0.23 11.6 3.9 1.3 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 DUF3450 PF11932.8 CBY18462.1 - 0.28 10.4 9.5 1.5 8.0 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 CBY18462.1 - 0.3 10.4 5.9 0.41 9.9 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 CBY18462.1 - 0.69 10.2 5.0 0.45 10.8 2.3 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 CBY18462.1 - 0.99 8.2 4.7 1.2 7.9 4.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein THOC7 PF05615.13 CBY18462.1 - 1.1 9.6 10.5 1 9.7 8.0 1.9 1 1 1 2 2 2 0 Tho complex subunit 7 Spc7 PF08317.11 CBY18462.1 - 1.9 7.3 14.8 1.1 8.1 11.7 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein FliD_N PF02465.18 CBY18462.1 - 2.6 8.8 8.7 12 6.7 1.0 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TMPIT PF07851.13 CBY18462.1 - 2.8 7.1 8.2 2.4 7.3 6.5 1.5 1 1 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 CBY18462.1 - 3.1 8.1 19.5 6.9e+02 0.5 19.5 2.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MnmE_helical PF12631.7 CBY18462.1 - 4.4 7.4 14.1 9.6 6.3 14.1 1.6 1 1 0 1 1 1 0 MnmE helical domain Occludin_ELL PF07303.13 CBY18462.1 - 6.3 7.6 9.9 1.1 10.0 2.9 2.3 1 1 1 2 2 2 0 Occludin homology domain MCM PF00493.23 CBY18463.1 - 1.7e-96 321.7 0.2 2.4e-96 321.1 0.2 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY18463.1 - 5.1e-31 107.1 2.0 1e-30 106.2 2.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBY18463.1 - 4e-25 88.1 0.2 9.8e-25 86.8 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 CBY18463.1 - 6e-21 74.7 0.0 1.4e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 CBY18463.1 - 1.2e-14 54.8 2.7 5.4e-14 52.6 0.5 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY18463.1 - 1.1e-07 31.5 0.1 1.5e-05 24.5 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY18463.1 - 6.6e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY18463.1 - 0.0001 22.1 0.0 0.00058 19.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY18463.1 - 0.00035 20.3 0.0 0.0011 18.6 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain Ank_2 PF12796.7 CBY18464.1 - 1.7e-45 153.5 3.1 1.4e-14 54.4 0.0 5.2 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY18464.1 - 1.2e-38 126.7 0.7 8.6e-05 22.7 0.0 9.3 8 1 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 CBY18464.1 - 5.5e-36 122.5 5.0 2.4e-09 37.5 0.1 7.2 3 3 6 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 CBY18464.1 - 9.2e-30 101.8 1.7 0.00014 22.2 0.4 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 CBY18464.1 - 2.4e-28 97.8 1.4 1.9e-06 28.0 0.3 7.3 4 3 4 8 8 8 7 Ankyrin repeats (many copies) DUF2072 PF09845.9 CBY18464.1 - 0.14 12.4 1.7 0.65 10.3 0.0 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein RE_TaqI PF09573.10 CBY18464.1 - 0.28 10.9 2.6 1.2 8.9 0.3 2.3 2 0 0 2 2 2 0 TaqI restriction endonuclease Orn_Arg_deC_N PF02784.16 CBY18465.1 - 6.8e-42 143.5 0.0 8.5e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CBY18465.1 - 2.3e-11 43.8 0.0 4.3e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Laminin_N PF00055.17 CBY18469.1 - 2.5e-16 60.0 0.0 7e-16 58.5 0.0 1.6 1 1 0 1 1 1 1 Laminin N-terminal (Domain VI) 7tm_2 PF00002.24 CBY18470.1 - 1.1e-42 146.0 17.9 1.4e-42 145.6 17.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) PAP_central PF04928.17 CBY18470.1 - 0.18 10.7 0.6 0.26 10.2 0.6 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain UAA PF08449.11 CBY18471.1 - 2.5e-23 82.7 22.4 3e-23 82.5 22.4 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBY18471.1 - 9.7e-10 38.3 16.0 1.3e-09 37.9 16.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY18471.1 - 0.00013 22.2 28.8 0.00044 20.4 6.8 2.6 3 0 0 3 3 3 2 EamA-like transporter family DUF1129 PF06570.11 CBY18471.1 - 0.52 9.8 6.8 0.061 12.8 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DnaJ PF00226.31 CBY18472.1 - 1.3e-26 92.5 1.9 2.8e-26 91.4 1.9 1.6 1 0 0 1 1 1 1 DnaJ domain NYD-SP28 PF14772.6 CBY18474.1 - 2.4e-21 75.7 16.9 2.4e-21 75.7 16.9 5.4 2 2 2 5 5 5 2 Sperm tail NYD-SP28_assoc PF14775.6 CBY18474.1 - 4.7e-07 29.8 2.1 4.7e-07 29.8 2.1 3.8 3 0 0 3 3 3 1 Sperm tail C-terminal domain Lectin_N PF03954.14 CBY18474.1 - 2.9 7.7 27.6 2.5 7.9 5.2 4.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Radial_spoke PF04712.12 CBY18475.1 - 1.2e-08 34.4 0.1 4.5e-06 25.9 0.1 2.2 2 1 0 2 2 2 2 Radial spokehead-like protein XendoU PF09412.10 CBY18476.1 - 6.1e-83 278.1 0.0 6.9e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 CBY18476.1 - 0.0022 18.3 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial EndoU nuclease Pkinase PF00069.25 CBY18477.1 - 7.9e-41 140.2 0.0 1.1e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18477.1 - 2e-16 60.1 0.0 2.7e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY18477.1 - 1.1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY18477.1 - 0.00011 22.2 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY18477.1 - 0.00028 19.8 0.0 0.00039 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY18477.1 - 0.00089 18.3 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CBY18477.1 - 0.025 14.1 0.1 0.059 12.9 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 CBY18477.1 - 0.062 12.6 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 CBY18477.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Zona_pellucida PF00100.23 CBY18478.1 - 1.2e-40 140.0 2.8 2e-40 139.2 2.8 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain EGF_CA PF07645.15 CBY18478.1 - 4.3e-05 23.6 9.5 4.3e-05 23.6 9.5 6.6 5 2 0 5 5 5 3 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 CBY18478.1 - 1.4 9.3 33.8 1.2 9.6 3.6 5.8 5 0 0 5 5 5 0 Pvs28 EGF domain ATP-gua_Ptrans PF00217.19 CBY18479.1 - 3.1e-78 262.1 0.0 4.1e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY18479.1 - 1.3e-29 102.3 0.0 2.4e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain AdoMet_MTase PF07757.13 CBY18480.1 - 1.2e-40 138.3 0.0 2.6e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 CBY18480.1 - 0.0019 17.8 0.2 0.038 13.6 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 CBY18480.1 - 0.0036 17.1 0.7 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY18480.1 - 0.0082 16.0 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBY18480.1 - 0.039 14.0 0.5 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CBY18480.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 CBY18480.1 - 0.12 13.0 0.0 0.32 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_114 PF03537.13 CBY18480.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Methyltransf_25 PF13649.6 CBY18480.1 - 0.18 12.5 0.0 0.6 10.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain MAM1 PF10434.9 CBY18482.1 - 0.24 11.0 0.1 0.24 11.0 0.1 4.0 4 1 1 5 5 5 0 Monopolin complex protein MAM1 ECH_1 PF00378.20 CBY18483.1 - 6.1e-38 130.6 0.0 7.5e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY18483.1 - 2.4e-11 43.7 0.0 3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CBY18483.1 - 0.0046 16.9 0.1 0.93 9.4 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 GDP_Man_Dehyd PF16363.5 CBY18484.1 - 1.3e-153 511.3 0.0 1.5e-153 511.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY18484.1 - 2.2e-70 236.9 0.1 2.7e-70 236.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CBY18484.1 - 0.00013 21.2 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CBY18484.1 - 0.0002 20.6 0.0 0.00044 19.4 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 CBY18484.1 - 0.035 13.6 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Amdo_NSP PF12475.8 CBY18484.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Amdovirus non-structural protein SH3_9 PF14604.6 CBY18485.1 - 2.3e-13 49.8 0.0 6.7e-06 25.9 0.0 3.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CBY18485.1 - 2.3e-07 30.4 0.0 8.3e-05 22.2 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 CBY18485.1 - 7.3e-06 25.5 1.3 0.024 14.2 0.0 3.2 3 1 0 3 3 3 2 SH3 domain bZIP_1 PF00170.21 CBY18485.1 - 7.3 6.8 7.8 1.3 9.2 1.8 2.9 3 0 0 3 3 3 0 bZIP transcription factor zf-C4 PF00105.18 CBY18486.1 - 3.3e-16 59.5 10.1 6.6e-16 58.5 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 CBY18486.1 - 0.041 14.0 1.5 0.099 12.8 1.5 1.7 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Hormone_recep PF00104.30 CBY18486.1 - 0.071 12.7 0.0 0.21 11.2 0.0 1.8 2 1 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor Ldl_recept_a PF00057.18 CBY18488.1 - 1.6e-09 37.8 12.1 6.9e-08 32.6 4.9 2.7 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.7 CBY18488.1 - 0.0036 17.1 5.9 0.0057 16.5 5.9 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Cas_Csy4 PF09618.10 CBY18488.1 - 0.071 13.2 0.6 0.1 12.7 0.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) MRP-S35 PF10246.9 CBY18489.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 PseudoU_synth_1 PF01416.20 CBY18490.1 - 2.2e-34 118.1 0.0 6.9e-28 97.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase UPF0240 PF06784.11 CBY18490.1 - 0.004 17.2 0.8 0.0069 16.5 0.8 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) YabA PF06156.13 CBY18490.1 - 0.78 10.4 4.4 1.7 9.3 4.4 1.6 1 0 0 1 1 1 0 Initiation control protein YabA GPS2_interact PF15784.5 CBY18490.1 - 3.2 8.3 11.3 6.6 7.2 11.3 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain GTP_EFTU PF00009.27 CBY18491.1 - 1.2e-61 207.6 0.0 1.9e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBY18491.1 - 4.2e-26 90.8 0.0 9.3e-26 89.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CBY18491.1 - 1.9e-24 85.8 0.0 4.3e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CBY18491.1 - 2.4e-18 65.9 0.0 5.8e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CBY18491.1 - 2.7e-11 43.7 0.0 5.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CBY18491.1 - 0.00059 19.7 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CBY18491.1 - 0.0011 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY18491.1 - 0.0073 15.8 0.0 0.026 14.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 CBY18491.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 CBY18491.1 - 0.018 15.0 0.1 0.2 11.5 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase Amidohydro_1 PF01979.20 CBY18491.1 - 0.025 13.9 0.1 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family SRPRB PF09439.10 CBY18491.1 - 0.11 11.9 0.0 0.61 9.5 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Endosulfine PF04667.17 CBY18492.1 - 2.6e-10 40.3 0.9 4.4e-10 39.6 0.9 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Asp_Arg_Hydrox PF05118.15 CBY18493.1 - 1.4e-53 180.9 0.7 2.3e-53 180.2 0.7 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_2 PF07719.17 CBY18493.1 - 1.5e-09 37.2 0.0 0.057 13.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY18493.1 - 2e-06 27.4 0.0 0.049 13.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY18493.1 - 0.00027 21.5 0.3 0.78 10.7 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY18493.1 - 0.0024 18.1 0.2 7.7 6.9 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY18493.1 - 0.0047 17.5 0.4 7 7.4 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY18493.1 - 0.0074 16.4 0.0 7.7 7.0 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY18493.1 - 0.0089 16.6 0.2 56 4.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY18493.1 - 0.014 15.8 0.0 0.053 13.9 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat UPF0253 PF06786.12 CBY18493.1 - 0.021 15.1 1.6 0.043 14.1 1.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) TPR_19 PF14559.6 CBY18493.1 - 0.025 15.1 0.4 16 6.1 0.3 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY18493.1 - 0.22 11.5 10.3 9.2 6.3 0.1 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat ATG16 PF08614.11 CBY18495.1 - 0.0023 18.2 3.4 0.0058 16.9 3.4 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Cnn_1N PF07989.11 CBY18495.1 - 0.015 15.4 0.8 0.56 10.4 0.0 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 CBY18495.1 - 0.017 14.5 1.3 0.017 14.5 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 CBY18495.1 - 0.026 13.9 0.4 0.031 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 CBY18495.1 - 0.026 14.6 2.2 0.098 12.7 0.1 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation E2F_CC-MB PF16421.5 CBY18495.1 - 0.056 13.8 1.2 0.67 10.3 0.1 2.5 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain Atg14 PF10186.9 CBY18495.1 - 0.084 11.9 4.6 0.11 11.5 4.4 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 CBY18495.1 - 0.085 13.4 4.6 1.3 9.6 0.2 2.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Ax_dynein_light PF10211.9 CBY18495.1 - 0.18 11.7 6.7 0.46 10.4 0.9 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain Rho_Binding PF08912.11 CBY18495.1 - 0.33 11.8 4.8 0.22 12.4 0.8 2.4 2 0 0 2 2 2 0 Rho Binding GIT_CC PF16559.5 CBY18495.1 - 0.37 10.7 4.9 0.48 10.3 1.4 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 CBY18495.1 - 0.38 10.1 8.0 2.3 7.5 8.1 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 CBY18495.1 - 0.43 10.6 0.1 0.43 10.6 0.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit PRKG1_interact PF15898.5 CBY18495.1 - 0.67 10.9 10.1 0.071 14.0 5.0 2.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 CBY18495.1 - 0.68 10.5 5.9 0.53 10.8 0.2 2.7 2 1 1 3 3 3 0 Apg6 coiled-coil region KLRAQ PF10205.9 CBY18495.1 - 0.85 9.9 6.3 1.5 9.1 3.6 2.5 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Sec2p PF06428.11 CBY18495.1 - 1.6 8.8 7.0 0.18 11.8 0.8 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p bZIP_Maf PF03131.17 CBY18495.1 - 1.7 9.3 9.7 12 6.4 1.2 3.1 2 1 1 3 3 3 0 bZIP Maf transcription factor DivIC PF04977.15 CBY18495.1 - 2.5 7.9 8.4 0.33 10.8 1.3 2.8 1 1 1 2 2 2 0 Septum formation initiator Uds1 PF15456.6 CBY18495.1 - 3.1 8.0 9.0 3.5 7.8 5.6 2.4 1 1 1 2 2 2 0 Up-regulated During Septation FPL PF09758.9 CBY18497.1 - 2e-60 203.1 7.3 2e-60 203.1 7.3 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein Herpes_heli_pri PF05774.11 CBY18497.1 - 0.039 14.2 0.2 0.13 12.5 0.2 1.8 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component zf-C2H2 PF00096.26 CBY18499.1 - 0.00031 21.0 10.5 0.00072 19.9 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY18499.1 - 0.0051 17.5 1.2 0.0051 17.5 1.2 3.2 2 1 0 2 2 2 1 C2H2-type zinc finger PMC2NT PF08066.12 CBY18499.1 - 0.73 10.6 3.5 3.2 8.5 0.0 2.7 3 0 0 3 3 3 0 PMC2NT (NUC016) domain zf-H2C2_2 PF13465.6 CBY18499.1 - 1.2 9.7 15.1 8.9 6.9 0.9 3.7 3 0 0 3 3 3 0 Zinc-finger double domain HAT PF02184.16 CBY18500.1 - 1.1e-31 108.5 64.0 1.6e-15 56.8 0.6 13.4 13 3 0 13 13 12 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CBY18500.1 - 3.6e-19 67.8 29.4 0.072 13.9 0.1 12.7 5 4 9 14 14 14 7 Tetratricopeptide repeat Suf PF05843.14 CBY18500.1 - 2.8e-17 63.6 20.4 2.3e-05 24.6 2.5 6.4 1 1 5 6 6 6 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CBY18500.1 - 7.2e-13 48.8 0.0 0.17 12.4 0.1 7.5 4 2 5 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY18500.1 - 1.8e-08 34.2 5.1 0.0096 16.2 0.0 7.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY18500.1 - 1.9e-08 34.8 4.0 5.5 7.7 0.1 7.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY18500.1 - 1.1e-05 25.8 16.8 17 6.3 0.1 10.0 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY18500.1 - 1.8e-05 24.5 29.2 2.3 8.5 0.7 10.9 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY18500.1 - 9.1e-05 22.4 5.1 2.6 8.5 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY18500.1 - 0.00081 19.5 7.7 1.4 9.2 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBY18500.1 - 0.001 19.1 25.9 0.0096 15.9 0.7 6.6 4 2 1 5 5 5 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 CBY18500.1 - 0.0013 19.0 12.6 3.5 8.0 0.0 7.3 7 2 2 9 9 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY18500.1 - 0.0031 17.5 7.2 0.94 9.6 0.1 5.4 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.11 CBY18500.1 - 0.01 15.9 27.2 0.03 14.4 2.5 7.7 6 4 3 9 9 9 0 U3 small nucleolar RNA-associated protein 6 MIT PF04212.18 CBY18500.1 - 0.05 13.7 7.1 4 7.6 0.1 4.1 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 CBY18500.1 - 0.085 12.2 5.2 0.42 9.9 1.0 3.2 3 0 0 3 3 3 0 MalT-like TPR region ZNRF_3_ecto PF18212.1 CBY18500.1 - 0.12 12.4 0.0 1.7 8.7 0.0 3.0 4 0 0 4 4 4 0 ZNRF-3 Ectodomain ANAPC3 PF12895.7 CBY18500.1 - 0.22 11.7 9.3 8.2 6.7 0.1 5.4 5 1 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Pecanex_C PF05041.15 CBY18501.1 - 9.4e-62 208.6 3.6 6.1e-60 202.6 3.6 2.4 1 1 0 1 1 1 1 Pecanex protein (C-terminus) IL6Ra-bind PF09240.10 CBY18503.1 - 0.017 15.5 0.1 0.037 14.5 0.1 1.5 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding Rad52_Rad22 PF04098.15 CBY18503.1 - 0.063 13.2 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein Ldl_recept_a PF00057.18 CBY18504.1 - 4.7e-60 199.5 222.9 8.7e-10 38.7 6.3 16.6 15 3 2 17 17 17 13 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 CBY18504.1 - 1.8e-07 31.5 2.7 1.8e-06 28.4 0.2 3.6 4 0 0 4 4 4 1 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.7 CBY18505.1 - 9.9e-10 38.4 7.3 2e-09 37.5 7.3 1.6 1 0 0 1 1 1 1 EGF domain EGF_CA PF07645.15 CBY18505.1 - 2.5e-07 30.8 4.3 2.5e-07 30.8 4.3 1.7 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 CBY18505.1 - 0.0004 20.6 5.8 0.00078 19.7 5.8 1.5 1 0 0 1 1 1 1 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY18505.1 - 0.0018 18.5 5.0 0.0052 17.1 5.0 1.8 1 0 0 1 1 1 1 Pvs28 EGF domain hEGF PF12661.7 CBY18505.1 - 0.023 15.4 3.5 0.064 13.9 3.5 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF cEGF PF12662.7 CBY18505.1 - 0.046 13.6 0.1 0.046 13.6 0.1 1.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY18505.1 - 0.061 13.4 2.2 0.14 12.2 2.2 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY18505.1 - 0.096 13.0 4.0 0.22 11.8 4.0 1.6 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site EF-hand_1 PF00036.32 CBY18506.1 - 1.5e-09 36.7 1.1 0.0058 16.1 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY18506.1 - 1.2e-08 34.2 0.1 0.0054 16.6 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBY18506.1 - 2.2e-07 31.2 0.5 0.011 16.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY18506.1 - 8.1e-07 28.8 3.3 0.011 15.6 0.1 3.2 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY18506.1 - 0.00045 19.6 0.3 0.00045 19.6 0.3 2.5 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 CBY18506.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 CBY18509.1 - 2.6e-41 141.8 0.0 3.5e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18509.1 - 2.4e-15 56.5 0.0 3.4e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY18509.1 - 5.3e-10 39.0 0.0 8.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY18509.1 - 5e-05 22.3 0.0 6.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY18509.1 - 8.1e-05 21.7 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY18509.1 - 0.0014 18.6 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY18509.1 - 0.005 16.5 0.2 0.013 15.1 0.2 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CBY18509.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like GST_N PF02798.20 CBY18510.1 - 9.8e-07 29.0 0.0 1.1e-06 28.9 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY18510.1 - 4.9e-05 23.7 0.0 6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY18510.1 - 0.00033 20.9 0.0 0.00047 20.4 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DHR10 PF18595.1 CBY18511.1 - 0.0081 16.2 7.2 0.016 15.2 7.2 1.5 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Membralin PF09746.9 CBY18511.1 - 0.029 13.4 1.8 0.03 13.4 1.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF16 PF01519.16 CBY18512.1 - 0.00076 19.9 1.5 0.0018 18.8 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF16 SKA2 PF16740.5 CBY18512.1 - 0.35 10.7 3.8 0.25 11.1 0.8 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Gp_dh_N PF00044.24 CBY18513.1 - 1.8e-25 89.2 0.2 2.3e-25 88.8 0.2 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBY18513.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Anoctamin PF04547.12 CBY18514.1 - 8.2e-73 245.8 13.5 9.8e-73 245.5 13.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3021 PF11457.8 CBY18514.1 - 0.011 16.1 1.1 0.011 16.1 1.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3021) Ribosomal_L3 PF00297.22 CBY18514.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L3 ECF_trnsprt PF12822.7 CBY18514.1 - 3.5 7.7 10.5 0.23 11.5 3.2 2.5 1 1 2 3 3 3 0 ECF transporter, substrate-specific component Pkinase PF00069.25 CBY18516.1 - 1.7e-55 188.3 0.2 7e-55 186.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18516.1 - 6.9e-43 146.8 0.0 6.9e-43 146.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase OSR1_C PF12202.8 CBY18516.1 - 4.6e-06 26.8 0.1 1.7e-05 25.0 0.1 2.1 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Kdo PF06293.14 CBY18516.1 - 0.004 16.5 0.0 0.013 14.8 0.0 1.9 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY18516.1 - 0.62 9.9 0.0 0.62 9.9 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Spt5_N PF11942.8 CBY18517.1 - 0.014 16.3 4.0 0.016 16.1 4.0 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal UQ_con PF00179.26 CBY18518.1 - 1.7e-09 37.5 0.0 3.9e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CIA30 PF08547.12 CBY18519.1 - 3.3e-26 92.2 0.0 4.1e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 CBY18519.1 - 0.0011 18.9 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) SGBP_B_XBD PF18329.1 CBY18519.1 - 0.0021 18.1 0.0 0.0071 16.3 0.0 1.7 1 1 1 2 2 2 1 Surface glycan-binding protein B xyloglucan binding domain Cnd1 PF12717.7 CBY18520.1 - 0.021 14.9 0.6 0.037 14.1 0.6 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF4306 PF14154.6 CBY18520.1 - 0.049 13.8 1.0 0.14 12.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) DHHC PF01529.20 CBY18522.1 - 5.8e-32 110.6 0.9 5.8e-32 110.6 0.9 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase PHO4 PF01384.20 CBY18522.1 - 0.13 11.2 2.1 1.8 7.5 0.2 2.1 2 0 0 2 2 2 0 Phosphate transporter family DUF1272 PF06906.11 CBY18522.1 - 0.71 10.0 7.6 0.074 13.2 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) HXXEE PF13787.6 CBY18522.1 - 2.2 9.1 7.7 2.3 9.1 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Topoisom_bac PF01131.20 CBY18523.1 - 1.9e-112 376.3 0.0 2.4e-112 376.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CBY18523.1 - 1.7e-17 63.5 0.0 3.4e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Toprim domain TFIIA PF03153.13 CBY18524.1 - 1.3 8.9 14.6 1.6 8.7 14.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ion_trans_2 PF07885.16 CBY18525.1 - 0.0051 16.8 0.8 0.0067 16.4 0.8 1.2 1 0 0 1 1 1 1 Ion channel zf-C2H2 PF00096.26 CBY18526.1 - 7.4e-06 26.1 12.6 0.017 15.5 2.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY18526.1 - 0.00078 19.8 2.2 0.00078 19.8 2.2 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY18526.1 - 0.032 15.1 1.9 0.032 15.1 1.9 3.4 2 1 0 2 2 2 0 C2H2-type zinc finger BTB_2 PF02214.22 CBY18527.1 - 4.3e-17 62.2 0.0 1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Laminin_EGF PF00053.24 CBY18528.1 - 5.8e-129 420.1 434.4 8.7e-11 41.8 15.8 23.6 18 4 5 23 23 23 20 Laminin EGF domain Laminin_N PF00055.17 CBY18528.1 - 6.9e-71 238.5 0.0 6.9e-71 238.5 0.0 3.7 3 1 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_G_2 PF02210.24 CBY18528.1 - 2.7e-26 92.6 0.6 8.7e-07 29.6 0.0 5.7 6 0 0 6 6 6 4 Laminin G domain Laminin_B PF00052.18 CBY18528.1 - 9.9e-20 70.8 0.0 5.8e-19 68.3 0.0 2.2 2 0 0 2 2 2 1 Laminin B (Domain IV) Laminin_G_1 PF00054.23 CBY18528.1 - 1.2e-12 48.2 0.1 0.00094 19.4 0.0 5.7 5 1 0 5 5 5 2 Laminin G domain F5_F8_type_C PF00754.25 CBY18528.1 - 0.00046 20.3 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain SKA2 PF16740.5 CBY18528.1 - 0.55 10.0 4.3 0.36 10.6 1.3 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Ribosomal_L34e PF01199.18 CBY18528.1 - 3.9 7.8 6.4 1 9.7 0.4 3.3 2 0 0 2 2 2 0 Ribosomal protein L34e PMC2NT PF08066.12 CBY18528.1 - 4 8.2 8.1 4.7 8.0 1.3 2.7 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Glycophorin_A PF01102.18 CBY18529.1 - 0.0015 18.7 0.0 0.0067 16.6 0.0 2.1 1 0 0 1 1 1 1 Glycophorin A NPR3 PF03666.13 CBY18529.1 - 0.0068 15.2 0.1 0.0068 15.2 0.1 1.9 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 B12D PF06522.11 CBY18529.1 - 0.095 12.5 2.0 0.2 11.5 0.0 2.5 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Syndecan PF01034.20 CBY18529.1 - 0.23 11.4 0.6 0.55 10.2 0.6 1.7 1 0 0 1 1 1 0 Syndecan domain EELM2 PF15863.5 CBY18530.1 - 0.32 11.1 4.8 9.4 6.3 0.3 3.0 3 0 0 3 3 3 0 Extended EGL-27 and MTA1 homology domain FapA PF03961.13 CBY18530.1 - 2.9 6.4 17.2 2.9 6.4 3.9 2.8 2 1 1 3 3 3 0 Flagellar Assembly Protein A ABC_tran_CTD PF16326.5 CBY18530.1 - 3.6 7.9 18.5 4 7.8 2.2 4.4 3 1 1 4 4 4 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 CBY18530.1 - 3.9 7.5 31.1 3.3 7.7 1.7 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3439 PF11921.8 CBY18531.1 - 0.19 11.7 4.7 0.37 10.8 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.11 CBY18531.1 - 0.34 9.0 2.1 0.45 8.5 2.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 CBY18532.1 - 2.9e-30 105.5 0.1 6.9e-14 51.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain TSP_1 PF00090.19 CBY18532.1 - 4e-17 62.2 65.0 2.6e-10 40.3 9.3 5.5 5 0 0 5 5 5 3 Thrombospondin type 1 domain CAP PF00188.26 CBY18532.1 - 9.3e-14 52.3 0.1 3.6e-13 50.5 0.1 2.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase_Tyr PF07714.17 CBY18532.1 - 4.2e-11 42.6 0.1 3.1e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Nucleocap_ssRNA PF11128.8 CBY18532.1 - 0.031 14.0 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid 7TM_GPCR_Srw PF10324.9 CBY18532.1 - 0.2 10.9 0.3 0.46 9.7 0.3 1.6 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw PhoPQ_related PF10142.9 CBY18533.1 - 8.6e-73 245.1 0.2 1.3e-72 244.5 0.2 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Chitin_synth_2 PF03142.15 CBY18534.1 - 9.2e-28 97.1 3.7 9e-25 87.3 0.0 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 CBY18534.1 - 1.6e-08 34.8 0.0 3.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY18534.1 - 8.5e-07 29.1 10.3 3.2e-06 27.2 9.2 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 TetM_leader PF08076.11 CBY18534.1 - 0.014 15.1 0.6 0.035 13.9 0.6 1.7 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide DHR10 PF18595.1 CBY18535.1 - 0.0036 17.4 34.7 0.032 14.3 3.6 3.5 3 1 0 3 3 3 2 Designed helical repeat protein 10 domain DUF4201 PF13870.6 CBY18535.1 - 0.0061 16.3 15.8 0.0061 16.3 15.8 3.2 2 2 0 2 2 2 1 Domain of unknown function (DUF4201) DUF2935 PF11155.8 CBY18535.1 - 0.046 14.1 7.9 0.064 13.6 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) YkyA PF10368.9 CBY18535.1 - 0.069 12.8 28.7 0.8 9.3 12.7 2.7 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein PHM7_cyt PF14703.6 CBY18535.1 - 0.14 12.3 20.2 3 8.1 10.8 3.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Serine_rich PF08824.10 CBY18535.1 - 0.28 11.2 16.4 0.076 13.0 1.9 3.2 2 1 2 4 4 4 0 Serine rich protein interaction domain DUF5398 PF17376.2 CBY18535.1 - 0.36 11.5 5.7 0.3 11.7 3.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5398) DUF745 PF05335.13 CBY18535.1 - 0.64 9.7 13.4 0.38 10.5 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF745) COG2 PF06148.11 CBY18535.1 - 1.1 9.3 21.8 1.2 9.2 4.9 3.6 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 CBY18535.1 - 1.6 9.0 7.0 3 8.2 0.3 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HOOK PF05622.12 CBY18535.1 - 1.7 6.7 38.7 0.56 8.3 20.4 2.2 1 1 1 2 2 2 0 HOOK protein CENP-F_leu_zip PF10473.9 CBY18535.1 - 4 7.5 42.3 2.1 8.4 6.7 3.7 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 CBY18535.1 - 4.4 7.8 15.8 9.3 6.8 1.2 4.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein PriC PF07445.12 CBY18535.1 - 5.1 7.0 20.3 0.086 12.8 4.8 2.8 2 1 0 2 2 2 0 Primosomal replication protein priC ADIP PF11559.8 CBY18535.1 - 6 6.9 31.1 0.16 12.1 3.0 3.7 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.9 CBY18535.1 - 7.5 7.3 21.0 6.5 7.5 1.6 3.5 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 CBY18535.1 - 7.9 6.5 19.9 4.3 7.4 1.8 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) SseC PF04888.12 CBY18535.1 - 8.8 5.8 12.9 7 6.2 0.3 3.3 2 2 2 4 4 4 0 Secretion system effector C (SseC) like family TMF_TATA_bd PF12325.8 CBY18536.1 - 0.0012 19.0 4.8 0.0012 19.0 4.8 22.8 8 5 10 20 20 20 6 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 CBY18536.1 - 0.0039 17.3 0.9 0.0039 17.3 0.9 21.8 8 6 10 21 21 21 5 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 CBY18537.1 - 0.0014 18.9 4.8 0.0014 18.9 4.8 21.0 8 4 12 22 22 22 6 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 CBY18537.1 - 0.0042 17.2 0.9 0.0042 17.2 0.9 19.9 8 4 14 24 24 24 3 Afadin- and alpha -actinin-Binding Pkinase PF00069.25 CBY18538.1 - 7.9e-61 205.7 0.0 1.3e-60 205.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18538.1 - 7.6e-24 84.4 0.5 2.2e-23 82.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY18538.1 - 1.2e-09 37.9 0.4 2.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY18538.1 - 1.7e-07 30.8 0.0 3.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY18538.1 - 0.0052 16.7 0.3 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY18538.1 - 0.026 13.5 0.4 0.61 9.0 0.0 2.3 2 1 0 2 2 2 0 Haspin like kinase domain Reprolysin_3 PF13582.6 CBY18538.1 - 0.05 14.1 0.5 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Choline_kinase PF01633.20 CBY18538.1 - 0.1 12.2 1.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Macoilin PF09726.9 CBY18538.1 - 0.11 11.1 1.4 0.13 10.8 1.4 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase_fungal PF17667.1 CBY18538.1 - 0.15 10.8 5.3 0.63 8.7 5.3 1.9 1 1 0 1 1 1 0 Fungal protein kinase Mito_fiss_reg PF05308.11 CBY18538.1 - 0.95 9.5 11.7 1.4 8.9 11.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Na_Pi_cotrans PF02690.15 CBY18539.1 - 1.9e-14 54.0 1.7 2.9e-14 53.3 1.7 1.3 1 0 0 1 1 1 1 Na+/Pi-cotransporter OspD PF03207.13 CBY18539.1 - 0.039 13.3 0.4 0.083 12.2 0.4 1.4 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) Mucin PF01456.17 CBY18539.1 - 0.097 12.7 4.4 0.22 11.5 4.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SR-25 PF10500.9 CBY18539.1 - 0.29 10.7 13.8 0.2 11.3 6.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2207 PF09972.9 CBY18540.1 - 0.0013 17.5 0.9 0.0025 16.7 0.9 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Plexin_cytopl PF08337.12 CBY18542.1 - 2.8e-54 184.7 0.5 3.4e-54 184.5 0.5 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Phage_int_SAM_1 PF02899.17 CBY18542.1 - 0.084 13.2 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Plexin_cytopl PF08337.12 CBY18543.1 - 3.1e-58 197.8 0.0 5.7e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 CBY18543.1 - 3.8e-14 52.5 3.8 3.9e-09 36.5 0.0 3.5 4 0 0 4 4 4 2 IPT/TIG domain PSI PF01437.25 CBY18543.1 - 9.2e-08 32.5 42.9 6.4e-07 29.8 13.8 3.6 3 0 0 3 3 3 2 Plexin repeat Chordopox_A13L PF05961.11 CBY18543.1 - 0.0064 16.7 0.6 0.019 15.2 0.6 1.8 1 0 0 1 1 1 1 Chordopoxvirus A13L protein 60KD_IMP PF02096.20 CBY18543.1 - 0.035 14.0 0.8 0.062 13.2 0.8 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein ERGIC_N PF13850.6 CBY18543.1 - 0.1 13.0 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sigma_reg_N PF13800.6 CBY18543.1 - 0.23 11.8 1.3 0.61 10.4 1.3 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Thioredoxin_6 PF13848.6 CBY18544.1 - 1.1e-35 123.2 12.4 6.9e-35 120.6 1.7 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 CBY18544.1 - 3.4e-21 75.2 0.2 1.3e-20 73.3 0.1 2.1 2 0 0 2 2 1 1 Thioredoxin Calsequestrin PF01216.17 CBY18544.1 - 3e-10 39.7 0.9 3e-10 39.7 0.9 2.5 2 1 0 2 2 2 1 Calsequestrin DUF812 PF05667.11 CBY18544.1 - 0.00072 18.6 13.8 0.0012 17.9 13.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) OST3_OST6 PF04756.13 CBY18544.1 - 0.00098 18.6 0.4 0.002 17.6 0.1 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family HOOK PF05622.12 CBY18544.1 - 0.0019 16.5 23.5 0.0028 15.9 23.5 1.1 1 0 0 1 1 1 1 HOOK protein MRP-S27 PF10037.9 CBY18544.1 - 0.0021 17.0 10.2 0.0031 16.5 10.2 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 LMBR1 PF04791.16 CBY18544.1 - 0.0098 14.8 4.6 0.014 14.4 4.6 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein ERM PF00769.19 CBY18544.1 - 0.011 15.6 29.7 0.021 14.6 29.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Thioredoxin_8 PF13905.6 CBY18544.1 - 0.014 15.7 1.9 0.027 14.8 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 CBY18544.1 - 0.02 15.1 0.2 1.1 9.4 0.1 2.9 2 0 0 2 2 2 0 Thioredoxin-like Borrelia_P83 PF05262.11 CBY18544.1 - 0.035 12.6 15.4 0.048 12.2 15.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MCPsignal PF00015.21 CBY18544.1 - 0.045 13.5 5.9 0.09 12.6 5.9 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Thioredoxin_2 PF13098.6 CBY18544.1 - 0.1 13.1 0.1 0.1 13.1 0.1 3.6 3 2 0 3 3 2 0 Thioredoxin-like domain KxDL PF10241.9 CBY18544.1 - 0.12 12.7 10.1 0.51 10.6 2.5 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF3584 PF12128.8 CBY18544.1 - 0.14 9.7 22.5 0.19 9.2 22.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Questin_oxidase PF14027.6 CBY18544.1 - 0.16 11.4 7.9 0.35 10.4 7.9 1.6 1 1 0 1 1 1 0 Questin oxidase-like COG7 PF10191.9 CBY18544.1 - 0.19 10.0 11.0 0.28 9.4 11.0 1.2 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Laminin_II PF06009.12 CBY18544.1 - 0.23 11.4 17.5 0.52 10.3 14.6 2.6 2 1 1 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 CBY18544.1 - 0.25 10.9 8.9 0.43 10.1 8.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SKA2 PF16740.5 CBY18544.1 - 0.26 11.1 16.8 0.063 13.1 6.0 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 AATF-Che1 PF13339.6 CBY18544.1 - 0.27 11.9 13.8 1.4 9.6 13.7 2.2 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Flagellin_C PF00700.21 CBY18544.1 - 0.3 11.5 1.0 0.7 10.3 1.0 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Atg14 PF10186.9 CBY18544.1 - 0.36 9.9 11.0 0.78 8.8 11.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4175 PF13779.6 CBY18544.1 - 0.58 8.0 14.7 0.75 7.6 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RmuC PF02646.16 CBY18544.1 - 0.61 9.2 15.0 0.15 11.2 6.2 2.2 1 1 1 2 2 2 0 RmuC family DASH_Duo1 PF08651.10 CBY18544.1 - 1.1 9.0 6.4 0.44 10.4 2.5 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 YkyA PF10368.9 CBY18544.1 - 2.9 7.5 37.7 3.5 7.3 20.7 2.5 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Prominin PF05478.11 CBY18544.1 - 3.4 5.5 8.9 0.19 9.6 2.4 1.7 1 1 0 1 1 1 0 Prominin Syntaxin_2 PF14523.6 CBY18544.1 - 4.9 7.6 9.5 3.2 8.2 6.0 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Csm1_B PF18211.1 CBY18544.1 - 5.3 7.0 6.3 1.8 8.4 0.0 3.0 3 0 0 3 3 3 0 Csm1 subunit domain B CTD_bind PF04818.13 CBY18545.1 - 3.4e-14 53.4 0.0 8e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 CBY18545.1 - 0.012 15.8 0.8 0.037 14.2 0.8 1.8 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour CTK3 PF12243.8 CBY18545.1 - 0.077 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 GIDA_assoc PF13932.6 CBY18545.1 - 0.83 9.8 3.6 8.2 6.6 0.0 2.1 2 0 0 2 2 2 0 GidA associated domain DUF3841 PF12952.7 CBY18546.1 - 0.0013 18.6 1.3 0.0017 18.2 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3841) Ribosomal_L37 PF08561.10 CBY18546.1 - 0.0023 18.5 4.1 0.0033 17.9 4.1 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Coq4 PF05019.13 CBY18547.1 - 3.5e-71 239.1 0.0 4.4e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Ribosomal_L27 PF01016.19 CBY18548.1 - 0.013 15.5 0.0 0.085 12.9 0.0 2.1 1 1 0 1 1 1 0 Ribosomal L27 protein Collagen PF01391.18 CBY18550.1 - 4.5e-23 80.8 69.9 57 3.6 69.9 3.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) CwfJ_C_2 PF04676.14 CBY18551.1 - 2.6e-18 66.7 0.0 3.4e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 bVLRF1 PF18826.1 CBY18552.1 - 3.6e-33 114.5 0.1 8.1e-33 113.4 0.1 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 CBY18552.1 - 7.3e-11 41.8 1.8 1.8e-10 40.5 1.8 1.7 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_5 PF13857.6 CBY18552.1 - 1.4e-05 25.2 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY18552.1 - 0.00062 20.3 0.0 0.0021 18.6 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY18552.1 - 0.00099 19.4 0.0 0.005 17.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CBY18552.1 - 0.0015 18.9 0.1 0.0046 17.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 CBY18552.1 - 0.0016 19.0 0.0 0.018 15.6 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) TSP_1 PF00090.19 CBY18553.1 - 6.1e-07 29.6 33.8 0.00061 19.9 1.0 9.6 12 1 0 12 12 12 5 Thrombospondin type 1 domain BAF PF02961.14 CBY18554.1 - 1.4e-20 73.5 0.2 3.2e-20 72.3 0.1 1.6 2 0 0 2 2 2 1 Barrier to autointegration factor IMS_HHH PF11798.8 CBY18554.1 - 0.011 16.0 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif VAPB_antitox PF02697.14 CBY18554.1 - 0.19 12.5 4.7 0.15 12.9 1.5 2.4 2 1 0 2 2 2 0 Putative antitoxin V-ATPase_G PF03179.15 CBY18554.1 - 0.32 11.5 4.5 1.9 9.0 0.5 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit HAUS4 PF14735.6 CBY18554.1 - 1.4 8.6 7.7 0.41 10.3 2.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 4 Tub PF01167.18 CBY18555.1 - 6.7e-90 301.0 0.1 9.1e-90 300.6 0.1 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 CBY18555.1 - 0.017 14.7 0.0 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) PAT1 PF09770.9 CBY18555.1 - 0.036 12.4 3.3 0.057 11.7 3.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 COesterase PF00135.28 CBY18556.1 - 1.3e-86 291.5 0.4 1.8e-86 291.1 0.4 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY18556.1 - 1.3e-09 38.2 0.6 5e-09 36.3 0.6 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY18556.1 - 0.00013 21.5 0.3 0.00025 20.6 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Phospholip_A2_1 PF00068.19 CBY18557.1 - 1.8e-14 54.2 11.0 3.3e-14 53.3 11.0 1.4 1 0 0 1 1 1 1 Phospholipase A2 RBP_receptor PF14752.6 CBY18559.1 - 4.5e-51 174.2 25.5 1.8e-31 109.4 15.8 4.0 2 1 1 3 3 3 3 Retinol binding protein receptor Pox_Ag35 PF03286.14 CBY18560.1 - 0.013 15.3 5.9 0.017 14.9 5.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF5615 PF18480.1 CBY18560.1 - 0.086 12.6 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Ran_BP1 PF00638.18 CBY18561.1 - 2.3e-147 483.1 19.0 8.6e-42 142.3 0.2 6.6 5 1 0 5 5 5 5 RanBP1 domain WH1 PF00568.23 CBY18561.1 - 1e-06 28.7 0.1 0.27 11.2 0.0 3.8 3 0 0 3 3 3 2 WH1 domain TPR_1 PF00515.28 CBY18561.1 - 3.3e-06 26.7 7.8 0.00041 20.0 0.5 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY18561.1 - 2.2e-05 24.2 6.1 0.0011 19.0 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY18561.1 - 0.00012 22.1 4.5 0.19 12.0 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY18561.1 - 0.00028 21.1 0.7 0.023 15.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY18561.1 - 0.00049 19.9 0.2 0.44 10.7 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY18561.1 - 0.00067 20.1 0.7 0.02 15.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY18561.1 - 0.0017 18.5 0.1 0.0077 16.4 0.1 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CBY18561.1 - 0.021 15.5 0.6 0.61 10.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fib_alpha PF08702.10 CBY18561.1 - 0.039 14.1 5.6 0.22 11.7 5.1 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TPR_11 PF13414.6 CBY18561.1 - 0.1 12.3 1.7 1.2 8.9 0.0 2.7 2 1 0 2 2 2 0 TPR repeat TPR_9 PF13371.6 CBY18561.1 - 0.16 12.1 0.5 2 8.6 0.1 2.8 2 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CBY18561.1 - 0.23 11.6 1.8 12 6.1 0.1 3.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SlyX PF04102.12 CBY18561.1 - 0.53 10.9 3.4 0.96 10.1 0.4 3.0 3 0 0 3 3 2 0 SlyX Peptidase_S8 PF00082.22 CBY18562.1 - 3.6e-49 167.7 2.2 5.4e-49 167.1 2.2 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY18562.1 - 3.7e-20 71.8 0.0 8e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CBY18562.1 - 6.8e-12 46.0 0.6 1.6e-11 44.8 0.6 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain HgmA PF04209.13 CBY18563.1 - 7.4e-199 660.8 0.4 8.4e-199 660.6 0.4 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ntox44 PF15607.6 CBY18564.1 - 0.098 13.0 0.1 0.23 11.8 0.1 1.7 1 1 0 1 1 1 0 Bacterial toxin 44 DUF3040 PF11239.8 CBY18565.1 - 0.031 14.6 2.6 1.5 9.2 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) EGF_CA PF07645.15 CBY18567.1 - 6.5e-98 320.7 496.3 1.4e-08 34.8 5.1 41.2 30 10 10 40 40 40 29 Calcium-binding EGF domain cEGF PF12662.7 CBY18567.1 - 2.1e-33 113.9 216.4 1e-06 28.5 5.2 27.3 26 1 0 26 26 26 17 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY18567.1 - 3.2e-29 100.8 398.0 1.1e-08 35.1 11.2 38.8 36 5 4 40 40 40 20 EGF domain EGF PF00008.27 CBY18567.1 - 1.3e-05 25.4 21.6 0.00024 21.3 6.1 39.4 41 1 0 41 41 41 17 EGF-like domain EGF_MSP1_1 PF12946.7 CBY18567.1 - 0.004 17.2 7.9 0.004 17.2 7.9 23.3 25 0 0 25 25 25 8 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY18567.1 - 0.025 14.8 0.3 0.025 14.8 0.3 37.5 35 5 4 39 39 39 0 Coagulation Factor Xa inhibitory site Sulfotransfer_2 PF03567.14 CBY18568.1 - 1.5e-25 90.6 5.9 1.7e-25 90.4 2.8 2.1 2 0 0 2 2 2 1 Sulfotransferase family TRAM_LAG1_CLN8 PF03798.16 CBY18570.1 - 8e-21 74.7 17.4 1.3e-20 74.0 17.4 1.3 1 0 0 1 1 1 1 TLC domain RTA1 PF04479.13 CBY18570.1 - 0.047 13.3 0.7 4.6 6.8 0.0 2.4 2 1 0 2 2 2 0 RTA1 like protein DUF4207 PF13904.6 CBY18572.1 - 2e-09 37.6 69.4 3.1e-09 36.9 69.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) TP53IP5 PF15331.6 CBY18572.1 - 0.3 11.2 29.0 0.45 10.6 29.0 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Asp-B-Hydro_N PF05279.11 CBY18572.1 - 4.7 7.2 39.0 5.9 6.9 39.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1295 PF06966.12 CBY18574.1 - 1.4e-32 113.1 1.9 1.4e-32 113.1 1.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CBY18574.1 - 1.6e-05 25.0 0.1 3.4e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 CBY18574.1 - 0.026 14.9 0.0 0.07 13.6 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CBY18574.1 - 0.08 13.3 2.8 0.1 13.0 0.3 2.5 2 0 0 2 2 2 0 Phospholipid methyltransferase UPF0060 PF02694.15 CBY18574.1 - 0.75 10.1 5.8 2.2 8.6 4.4 2.4 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Thioredoxin PF00085.20 CBY18575.1 - 2.1e-09 37.3 0.0 4.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 CBY18575.1 - 4.1e-07 29.2 0.5 5.2e-07 28.9 0.5 1.1 1 0 0 1 1 1 1 Phosducin DUF3037 PF11236.8 CBY18575.1 - 0.025 15.0 0.1 0.046 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) FAM72 PF14976.6 CBY18576.1 - 0.028 14.5 0.4 0.041 14.0 0.4 1.3 1 0 0 1 1 1 0 FAM72 protein PIN_4 PF13638.6 CBY18577.1 - 9.2e-17 61.6 0.0 1.9e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 PIN domain WW PF00397.26 CBY18577.1 - 9.7e-08 32.0 0.6 9.7e-08 32.0 0.6 2.0 2 0 0 2 2 2 1 WW domain PIN_9 PF18477.1 CBY18577.1 - 0.033 14.5 0.0 0.57 10.5 0.0 2.3 2 0 0 2 2 2 0 PIN like domain Sld5 PF05916.11 CBY18578.1 - 0.077 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 GINS complex protein FKBP_C PF00254.28 CBY18579.1 - 1.8e-15 57.0 0.0 1.9e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N_2 PF18023.1 CBY18579.1 - 0.18 11.9 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 BDBT FKBP like N-terminal BTHB PF18410.1 CBY18580.1 - 4.7e-24 84.0 0.2 7.3e-24 83.4 0.2 1.3 1 0 0 1 1 1 1 Basic tilted helix bundle domain Ras PF00071.22 CBY18581.1 - 7.5e-57 191.4 0.2 8.7e-57 191.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY18581.1 - 7.4e-31 106.9 0.1 1.1e-30 106.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY18581.1 - 6.2e-12 45.3 0.1 7.1e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY18581.1 - 2.7e-07 30.3 0.1 3.4e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY18581.1 - 5.5e-06 26.4 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBY18581.1 - 4.2e-05 23.6 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 CBY18581.1 - 9.7e-05 21.8 0.0 0.00013 21.3 0.0 1.1 1 0 0 1 1 1 1 Septin Gtr1_RagA PF04670.12 CBY18581.1 - 0.00085 18.7 0.1 0.00097 18.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBY18581.1 - 0.0018 17.8 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CBY18581.1 - 0.006 16.9 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY18581.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY18581.1 - 0.026 14.9 0.0 0.027 14.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CBY18581.1 - 0.028 14.4 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.17 CBY18581.1 - 0.033 14.0 0.0 8.4 6.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 CBY18581.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CBY18581.1 - 0.058 12.8 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Lebercilin PF15619.6 CBY18582.1 - 1.6e-42 145.4 44.2 2.6e-42 144.7 44.2 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Macoilin PF09726.9 CBY18582.1 - 0.014 14.0 31.2 0.025 13.1 31.2 1.4 1 0 0 1 1 1 0 Macoilin family Aminotran_1_2 PF00155.21 CBY18582.1 - 0.22 10.7 2.9 0.093 11.9 0.4 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II GAS PF13851.6 CBY18582.1 - 0.24 10.8 37.0 0.05 12.9 31.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA PF00004.29 CBY18583.1 - 3.2e-15 56.7 0.2 9.5e-15 55.2 0.0 1.8 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CBY18583.1 - 7e-15 55.2 0.5 2.2e-14 53.6 0.2 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBY18583.1 - 5.7e-13 49.0 0.2 6.6e-11 42.3 0.0 2.8 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 CBY18583.1 - 5.4e-06 26.3 1.0 3.5e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 CBY18583.1 - 1.2e-05 25.1 0.5 0.00019 21.2 0.0 2.8 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CBY18583.1 - 1.7e-05 25.0 0.1 4.9e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 CBY18583.1 - 4.1e-05 23.5 0.2 0.00024 21.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 CBY18583.1 - 5.4e-05 23.2 0.0 0.00026 21.0 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CBY18583.1 - 6.6e-05 23.4 0.0 0.00026 21.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CBY18583.1 - 0.00017 21.4 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY18583.1 - 0.00044 20.5 1.3 0.082 13.2 0.1 3.0 2 2 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CBY18583.1 - 0.00054 19.4 0.0 0.026 13.9 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CBY18583.1 - 0.0011 19.4 0.3 0.0068 16.7 0.1 2.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 CBY18583.1 - 0.0065 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.16 CBY18583.1 - 0.014 14.9 0.1 0.74 9.2 0.0 2.4 1 1 1 2 2 2 0 PhoH-like protein DEAD PF00270.29 CBY18583.1 - 0.016 15.0 1.4 0.27 11.0 0.0 2.9 3 1 1 4 4 3 0 DEAD/DEAH box helicase DUF2075 PF09848.9 CBY18583.1 - 0.019 14.2 0.8 0.08 12.2 0.2 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CBY18583.1 - 0.023 14.5 0.1 0.21 11.3 0.0 2.6 2 1 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 CBY18583.1 - 0.025 14.0 0.2 1.9 7.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial TniB protein AAA_5 PF07728.14 CBY18583.1 - 0.025 14.6 0.1 0.14 12.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CBY18583.1 - 0.027 14.7 0.1 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CBY18583.1 - 0.029 14.0 0.0 0.32 10.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CBY18583.1 - 0.034 14.1 0.0 0.6 10.1 0.0 2.5 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CBY18583.1 - 0.035 14.5 0.1 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase PIF1 PF05970.14 CBY18583.1 - 0.036 13.2 0.1 0.12 11.5 0.1 2.0 1 1 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 CBY18583.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CBY18583.1 - 0.16 12.4 0.4 4.4 7.8 0.4 2.6 1 1 0 1 1 1 0 ABC transporter SH3_1 PF00018.28 CBY18584.1 - 1.1e-54 181.8 6.7 2.7e-14 52.5 0.1 4.6 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 CBY18584.1 - 1.6e-51 172.0 2.4 6.7e-14 51.5 0.1 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 CBY18584.1 - 8.4e-43 143.9 0.3 3e-13 49.2 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain RhoGEF PF00621.20 CBY18584.1 - 6.5e-22 78.6 0.3 9.7e-22 78.1 0.3 1.2 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 CBY18584.1 - 2.6e-05 24.1 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CBY18584.1 - 0.00046 20.7 0.0 0.00094 19.7 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_16 PF18348.1 CBY18584.1 - 0.00063 19.5 0.9 0.17 11.7 0.0 3.8 4 0 0 4 4 4 1 Bacterial dipeptidyl-peptidase Sh3 domain SH3_3 PF08239.11 CBY18584.1 - 0.00073 19.8 4.2 0.37 11.1 0.0 4.0 4 0 0 4 4 4 1 Bacterial SH3 domain DUF5348 PF17295.2 CBY18584.1 - 0.0021 17.9 0.0 5 7.1 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF5348) DUF4648 PF15505.6 CBY18584.1 - 0.0049 17.7 0.0 0.35 11.8 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4648) hSH3 PF14603.6 CBY18584.1 - 0.17 12.4 0.0 62 4.1 0.0 3.4 2 1 0 3 3 3 0 Helically-extended SH3 domain NDUF_B12 PF08122.12 CBY18586.1 - 1.3 9.1 3.9 11 6.1 0.0 3.9 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family SurA_N_3 PF13624.6 CBY18589.1 - 0.98 9.2 3.6 0.56 10.0 0.7 2.0 2 0 0 2 2 2 0 SurA N-terminal domain Macoilin PF09726.9 CBY18589.1 - 2.9 6.3 17.5 2.8 6.4 17.5 1.2 1 0 0 1 1 1 0 Macoilin family BTB_2 PF02214.22 CBY18590.1 - 5.4e-18 65.1 0.0 8.9e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CBY18590.1 - 0.0039 17.4 0.0 0.0069 16.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CBY18590.1 - 0.076 13.1 0.0 9.2 6.4 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain SERTA PF06031.13 CBY18591.1 - 0.023 14.3 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 SERTA motif SNAD2 PF18745.1 CBY18593.1 - 0.055 13.2 0.1 0.06 13.1 0.1 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 zf-CCHC PF00098.23 CBY18594.1 - 0.17 12.0 0.4 0.31 11.2 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Cir_N PF10197.9 CBY18595.1 - 1.4e-10 41.2 6.4 1.4e-10 41.2 6.4 6.5 6 1 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 CBY18595.1 - 2.8e-06 27.1 1.1 9.6e-06 25.3 1.1 1.9 1 0 0 1 1 1 1 Zinc knuckle DIM1 PF02966.16 CBY18596.1 - 9.6e-66 219.6 0.1 1.1e-65 219.4 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CBY18596.1 - 0.00092 19.2 0.4 0.0012 18.8 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin Cir_N PF10197.9 CBY18597.1 - 1.5e-08 34.6 5.4 1.5e-08 34.6 5.4 3.4 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 CBY18597.1 - 0.00032 20.5 0.2 0.0011 18.8 0.2 1.9 1 0 0 1 1 1 1 Zinc knuckle Ras PF00071.22 CBY18598.1 - 1.4e-56 190.6 0.0 1.5e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY18598.1 - 2.7e-24 85.7 0.0 3.6e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY18598.1 - 1.6e-10 40.7 0.0 2.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY18598.1 - 0.00016 21.3 0.2 0.00026 20.6 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBY18598.1 - 0.0029 17.1 0.0 0.004 16.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY18598.1 - 0.022 14.1 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CBY18598.1 - 0.038 13.7 0.0 7.1 6.4 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FAM219A PF15260.6 CBY18599.1 - 4.3e-10 40.0 0.6 4.6e-10 39.9 0.6 1.1 1 0 0 1 1 1 1 Protein family FAM219A TRAM_LAG1_CLN8 PF03798.16 CBY18600.1 - 4.1e-16 59.3 15.0 4.1e-16 59.3 15.0 1.9 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CBY18600.1 - 2.5e-15 55.9 0.0 2.5e-15 55.9 0.0 2.4 3 0 0 3 3 3 1 TRAM1-like protein Pinin_SDK_memA PF04696.13 CBY18601.1 - 6.8e-26 90.8 21.1 6.8e-26 90.8 21.1 4.2 2 1 2 4 4 4 1 pinin/SDK/memA/ protein conserved region DUF1664 PF07889.12 CBY18601.1 - 8.8 6.4 12.7 0.17 11.9 0.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) LEM PF03020.15 CBY18603.1 - 2.4e-18 65.4 0.1 2.4e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 LEM domain SPT6_acidic PF14632.6 CBY18603.1 - 0.038 14.6 1.8 0.038 14.6 1.8 1.9 1 1 1 2 2 2 0 Acidic N-terminal SPT6 AcrZ PF10766.9 CBY18603.1 - 0.16 11.6 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ GAS PF13851.6 CBY18604.1 - 0.0028 17.1 7.7 0.0028 17.1 7.7 3.5 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 CBY18604.1 - 0.0047 16.4 15.8 0.0047 16.4 15.8 3.0 1 1 2 3 3 3 1 Golgin subfamily A member 5 YceD PF02620.17 CBY18604.1 - 3.7 7.7 8.8 0.91 9.7 4.8 2.3 2 1 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD Atg8 PF02991.16 CBY18605.1 - 3.9e-35 120.2 0.0 4.5e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBY18605.1 - 6.1e-06 26.5 0.0 7.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 E1_DerP2_DerF2 PF02221.15 CBY18606.1 - 1.8e-05 25.2 0.1 0.00012 22.6 0.1 1.9 1 1 0 1 1 1 1 ML domain Pkinase PF00069.25 CBY18607.1 - 1.7e-47 162.0 0.0 2.9e-47 161.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18607.1 - 1.4e-29 103.2 0.0 6.2e-21 74.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY18607.1 - 6.1e-05 22.0 0.0 9.1e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY18607.1 - 0.043 13.2 0.2 0.092 12.1 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CBY18607.1 - 0.078 12.5 0.5 0.18 11.3 0.1 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 CBY18607.1 - 0.16 11.2 0.0 0.35 10.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Zona_pellucida PF00100.23 CBY18609.1 - 6.8e-07 29.3 0.0 7.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Myosin_head PF00063.21 CBY18610.1 - 3.1e-236 785.8 2.7 3.1e-236 785.8 2.7 2.8 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY18610.1 - 4.9e-132 441.9 270.0 6.2e-132 441.6 270.0 1.0 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.9 CBY18610.1 - 0.0013 18.8 31.3 0.0013 18.8 31.3 11.6 1 1 10 11 11 11 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.6 CBY18610.1 - 0.071 13.4 0.0 0.071 13.4 0.0 6.0 5 4 2 7 7 7 0 AAA domain T4bSS_IcmS PF12608.8 CBY18610.1 - 1.1 9.7 6.1 2.2 8.6 1.2 4.0 1 1 1 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment Myosin_head PF00063.21 CBY18611.1 - 2.3e-06 26.1 0.8 2.8e-06 25.9 0.8 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CBY18611.1 - 0.0054 16.5 0.7 0.0079 16.0 0.7 1.3 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain BUD22 PF09073.10 CBY18612.1 - 3.5e-07 29.9 20.8 3.5e-07 29.9 20.8 3.7 1 1 1 2 2 2 1 BUD22 Forkhead PF00250.18 CBY18613.1 - 2.9e-19 69.1 0.2 7.1e-19 67.9 0.2 1.6 1 0 0 1 1 1 1 Forkhead domain DUF1181 PF06680.11 CBY18613.1 - 0.031 14.1 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) Homeodomain PF00046.29 CBY18615.1 - 5.4e-21 74.2 1.0 1.1e-20 73.2 1.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY18615.1 - 0.017 15.0 0.1 0.067 13.1 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain DUF3402 PF11882.8 CBY18615.1 - 0.042 13.0 0.3 0.042 13.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Dna2 PF08696.11 CBY18615.1 - 0.21 11.4 3.0 0.13 12.1 1.3 1.4 2 0 0 2 2 2 0 DNA replication factor Dna2 EVI2A PF05399.11 CBY18615.1 - 0.45 10.1 7.1 0.13 11.9 0.4 2.1 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) An_peroxidase PF03098.15 CBY18616.1 - 1.6e-82 277.8 0.0 2.1e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Band_7 PF01145.25 CBY18618.1 - 3.9e-27 95.4 1.0 5.3e-27 95.0 1.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 CBY18618.1 - 0.0083 16.3 0.4 0.016 15.4 0.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 HA2 PF04408.23 CBY18619.1 - 2.8e-25 88.7 6.2 8.3e-25 87.2 0.0 3.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBY18619.1 - 3e-23 82.0 0.0 6.3e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBY18619.1 - 2e-13 50.7 0.0 1e-12 48.4 0.0 2.3 2 0 0 2 2 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CBY18619.1 - 9e-10 38.8 0.1 1.9e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 CBY18619.1 - 2.9e-06 27.6 0.3 1.3e-05 25.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 CBY18619.1 - 1.1e-05 25.3 1.2 3.1e-05 23.8 1.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBY18619.1 - 0.002 18.5 0.2 0.0058 17.0 0.2 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBY18619.1 - 0.004 16.3 0.1 0.01 14.9 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CBY18619.1 - 0.0043 16.8 0.1 0.0095 15.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF5427 PF10310.9 CBY18619.1 - 0.036 13.0 9.3 0.069 12.1 9.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) AAA_14 PF13173.6 CBY18619.1 - 0.039 14.0 0.4 0.31 11.1 0.4 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CBY18619.1 - 0.082 12.3 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 CBY18619.1 - 0.12 12.9 0.4 2.1 8.9 0.2 2.8 1 1 0 2 2 2 0 ABC transporter SRP54 PF00448.22 CBY18619.1 - 0.13 11.8 0.3 0.32 10.6 0.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4551 PF15087.6 CBY18619.1 - 0.19 10.6 7.7 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 CBY18619.1 - 0.91 7.7 13.0 2.1 6.5 13.0 1.5 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CBY18619.1 - 1.3 7.8 5.0 2.6 6.7 5.0 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EF-hand_6 PF13405.6 CBY18620.1 - 0.0039 17.0 0.1 0.21 11.6 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CBY18620.1 - 0.0071 15.8 0.0 1.5 8.6 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CBY18620.1 - 0.013 15.9 0.1 0.8 10.2 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_4 PF12763.7 CBY18620.1 - 0.12 12.3 0.1 1.5 8.8 0.0 2.4 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand MFS_1 PF07690.16 CBY18621.1 - 7.9e-45 153.3 6.4 1.1e-44 152.8 6.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY18621.1 - 8.8e-07 28.1 0.3 1.7e-06 27.2 0.3 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 CBY18621.1 - 0.00038 19.1 2.2 0.014 14.0 0.2 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 CBY18621.1 - 0.00074 18.9 1.9 0.0013 18.1 1.9 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 CBY18621.1 - 0.0017 17.3 4.9 0.0028 16.6 4.9 1.3 1 0 0 1 1 1 1 MFS_1 like family Mucin PF01456.17 CBY18622.1 - 0.011 15.8 18.5 0.012 15.6 18.5 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein ABC2_membrane_3 PF12698.7 CBY18622.1 - 0.027 13.6 0.6 0.04 13.0 0.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ATF7IP_BD PF16788.5 CBY18622.1 - 4.7 7.2 9.8 6.3 6.8 9.8 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain FSA_C PF10479.9 CBY18622.1 - 6.3 4.8 11.2 7.5 4.6 11.2 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-C3HC4_3 PF13920.6 CBY18623.1 - 1.1e-07 31.6 8.3 1.1e-07 31.6 8.3 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY18623.1 - 1.8e-06 28.1 11.7 1.8e-06 28.1 11.7 3.3 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CBY18623.1 - 9.7e-06 25.5 10.2 9.7e-06 25.5 10.2 3.4 4 0 0 4 4 4 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY18623.1 - 2.2e-05 24.2 8.6 2.2e-05 24.2 8.6 3.3 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY18623.1 - 4.5e-05 23.2 8.0 4.5e-05 23.2 8.0 3.2 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 CBY18623.1 - 0.00011 22.0 12.2 0.00011 22.0 12.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY18623.1 - 0.00082 19.2 12.3 0.00082 19.2 12.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY18623.1 - 0.0032 17.4 8.1 0.0032 17.4 8.1 3.2 2 2 1 3 3 3 1 RING-type zinc-finger DUF1272 PF06906.11 CBY18623.1 - 0.033 14.3 6.6 0.033 14.3 6.6 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1272) Elf1 PF05129.13 CBY18623.1 - 2 8.5 20.4 1.4 9.1 2.7 4.3 3 2 1 4 4 4 0 Transcription elongation factor Elf1 like FA_hydroxylase PF04116.13 CBY18624.1 - 2.7e-27 95.7 13.5 2.7e-27 95.7 13.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AbrB PF05145.12 CBY18624.1 - 0.12 11.3 0.0 0.27 10.1 0.0 1.5 1 0 0 1 1 1 0 Transition state regulatory protein AbrB Cullin PF00888.22 CBY18625.1 - 6e-205 682.5 29.1 8.1e-205 682.1 29.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBY18625.1 - 2.6e-29 101.0 0.9 1e-28 99.1 0.9 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain HisK_sensor PF18698.1 CBY18625.1 - 3.6 8.0 10.6 0.17 12.2 2.3 3.3 3 0 0 3 3 3 0 Histidine kinase sensor domain WAC_Acf1_DNA_bd PF10537.9 CBY18625.1 - 3.8 8.1 7.6 0.82 10.2 0.1 3.5 3 1 1 4 4 4 0 ATP-utilising chromatin assembly and remodelling N-terminal Glyco_hydro_4C PF11975.8 CBY18625.1 - 9.4 6.2 9.3 5.6 7.0 1.7 3.2 3 1 0 3 3 3 0 Family 4 glycosyl hydrolase C-terminal domain EF-hand_6 PF13405.6 CBY18626.1 - 1.8e-14 52.3 15.0 1.6e-05 24.5 0.1 4.4 4 1 1 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 CBY18626.1 - 3.2e-14 51.3 11.5 1.9e-05 23.9 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY18626.1 - 1.7e-13 50.8 5.5 5.6e-07 29.9 1.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY18626.1 - 5.7e-07 28.8 7.1 0.0093 15.4 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY18626.1 - 5.2e-05 23.0 11.8 0.00021 21.0 1.4 3.9 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 CBY18626.1 - 0.00012 22.3 0.2 1.8 9.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain Ras PF00071.22 CBY18627.1 - 1.1e-46 158.4 0.6 1.4e-46 158.0 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY18627.1 - 5.2e-11 42.8 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY18627.1 - 1.6e-05 24.5 0.1 1.9e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY18627.1 - 0.0006 19.8 0.1 0.00087 19.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CBY18627.1 - 0.00076 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 CBY18627.1 - 0.039 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Big_3_2 PF12245.8 CBY18627.1 - 0.052 13.8 0.0 0.31 11.3 0.0 2.0 1 1 1 2 2 2 0 Bacterial Ig-like domain AlkA_N PF06029.11 CBY18627.1 - 0.084 13.1 0.0 0.23 11.7 0.0 1.8 1 1 0 1 1 1 0 AlkA N-terminal domain LysM PF01476.20 CBY18628.1 - 6.9e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 LysM domain SET PF00856.28 CBY18629.1 - 0.081 13.3 0.0 0.086 13.2 0.0 1.2 1 0 0 1 1 1 0 SET domain Pre-SET PF05033.16 CBY18630.1 - 1.4e-16 61.1 13.4 1.4e-16 61.1 13.4 2.6 3 0 0 3 3 3 1 Pre-SET motif SET PF00856.28 CBY18630.1 - 1.7e-10 41.5 0.3 5.9e-10 39.8 0.3 1.9 1 1 0 1 1 1 1 SET domain Ank_2 PF12796.7 CBY18630.1 - 0.0091 16.6 0.1 0.26 11.9 0.0 2.8 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Amino_oxidase PF01593.24 CBY18631.1 - 2.2e-76 258.0 0.0 9.7e-76 255.9 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 CBY18631.1 - 1.7e-13 50.7 2.0 4e-13 49.5 0.1 2.6 3 0 0 3 3 3 1 SWIRM domain NAD_binding_8 PF13450.6 CBY18631.1 - 1.8e-09 37.7 0.1 3.7e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CBY18631.1 - 1.7e-05 24.4 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBY18631.1 - 3.2e-05 23.3 1.1 4.5e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBY18631.1 - 3.5e-05 23.6 0.3 6.1e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CBY18631.1 - 0.00018 20.3 0.2 0.00018 20.3 0.2 2.4 2 1 1 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 CBY18631.1 - 0.00019 20.7 0.2 0.00029 20.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CBY18631.1 - 0.0046 16.1 0.2 0.012 14.7 0.2 1.7 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CBY18631.1 - 0.0061 17.1 0.3 0.0061 17.1 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CBY18631.1 - 0.028 13.7 0.1 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CBY18631.1 - 0.061 12.5 0.3 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 CBY18631.1 - 0.12 11.6 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tudor_3 PF18115.1 CBY18631.1 - 0.17 11.8 0.1 0.45 10.4 0.1 1.7 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Exonuc_VII_L PF02601.15 CBY18631.1 - 4.7 6.7 6.7 7.8 6.0 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 CBY18631.1 - 9.6 5.0 5.5 14 4.4 5.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cullin PF00888.22 CBY18632.1 - 5.7e-55 187.1 18.0 6.8e-55 186.8 18.0 1.0 1 0 0 1 1 1 1 Cullin family Xpo1 PF08389.12 CBY18632.1 - 0.22 11.6 2.7 0.24 11.4 0.5 2.2 2 1 1 3 3 3 0 Exportin 1-like protein OSCP PF00213.18 CBY18632.1 - 0.31 11.1 3.8 0.9 9.6 0.1 2.8 2 2 2 4 4 4 0 ATP synthase delta (OSCP) subunit AbiH PF14253.6 CBY18632.1 - 3.1 7.6 16.9 5.7 6.7 4.7 2.7 2 1 0 2 2 2 0 Bacteriophage abortive infection AbiH Cullin PF00888.22 CBY18633.1 - 1e-49 169.8 2.1 1e-49 169.8 2.1 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CBY18633.1 - 2.4e-15 56.3 0.1 6.2e-14 51.8 0.0 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Lipocalin_8 PF16585.5 CBY18633.1 - 1.9 9.0 5.0 1 9.8 0.9 2.3 2 1 1 3 3 3 0 Lipocalin-like domain AA_permease_2 PF13520.6 CBY18634.1 - 3.9e-56 190.7 47.0 4.5e-56 190.5 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY18634.1 - 4.2e-22 78.4 36.8 5.7e-22 78.0 36.8 1.2 1 0 0 1 1 1 1 Amino acid permease Nuc_sug_transp PF04142.15 CBY18635.1 - 5.9e-05 22.4 20.2 0.0056 15.9 11.9 2.0 1 1 1 2 2 2 2 Nucleotide-sugar transporter Gal-3-0_sulfotr PF06990.11 CBY18636.1 - 4e-71 240.0 0.0 5.2e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY18636.1 - 0.00054 20.0 0.0 0.038 13.9 0.0 2.6 2 1 0 2 2 2 2 Sulfotransferase family Ribonuc_2-5A PF06479.12 CBY18637.1 - 3.9e-08 33.5 0.5 1.3e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A pEK499_p136 PF18736.1 CBY18637.1 - 0.00033 20.3 0.1 0.0008 19.1 0.1 1.7 1 0 0 1 1 1 1 HEPN pEK499 p136 C2 PF00168.30 CBY18638.1 - 0.00014 22.1 0.0 0.003 17.8 0.0 2.6 3 0 0 3 3 3 1 C2 domain Pex24p PF06398.11 CBY18638.1 - 0.00071 18.7 0.8 0.0012 17.9 0.8 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.10 CBY18638.1 - 0.0084 15.9 0.1 0.56 10.0 0.0 2.3 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Lyase_8_N PF08124.11 CBY18638.1 - 0.078 11.9 0.0 0.31 9.9 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Enkurin PF13864.6 CBY18639.1 - 8.3e-19 67.8 0.2 8.9e-19 67.7 0.2 1.0 1 0 0 1 1 1 1 Calmodulin-binding DUF5320 PF17253.2 CBY18639.1 - 0.19 12.8 0.0 0.21 12.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Ank_4 PF13637.6 CBY18640.1 - 4.8e-06 27.0 0.0 0.045 14.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY18640.1 - 6.6e-06 26.6 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY18640.1 - 0.00021 21.5 0.0 0.22 11.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Get5_C PF18514.1 CBY18640.1 - 0.038 13.7 0.3 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Get5 C-terminal domain TAF PF02969.17 CBY18640.1 - 0.15 12.3 0.0 37 4.6 0.0 2.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Ank_3 PF13606.6 CBY18640.1 - 0.15 12.7 0.0 5.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat zf-RING_5 PF14634.6 CBY18641.1 - 2.3e-09 37.1 15.8 4e-09 36.3 15.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY18641.1 - 7.9e-08 32.0 11.8 1.3e-07 31.4 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY18641.1 - 8.9e-05 22.7 15.3 0.00016 22.0 15.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY18641.1 - 0.0001 22.3 15.1 0.0054 16.7 8.5 2.4 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY18641.1 - 0.00011 22.0 12.0 0.00058 19.7 12.4 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY18641.1 - 0.00015 21.5 12.6 0.00025 20.8 12.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY18641.1 - 0.00071 19.4 11.2 0.0017 18.2 11.2 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY18641.1 - 0.0013 18.5 16.0 0.0024 17.6 16.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CBY18641.1 - 0.0045 16.4 4.7 0.0045 16.4 4.7 2.4 1 1 1 2 2 2 1 Rtf2 RING-finger FYVE PF01363.21 CBY18641.1 - 0.0067 16.5 12.4 0.019 15.1 8.1 2.5 1 1 1 2 2 2 1 FYVE zinc finger DUF2616 PF11077.8 CBY18641.1 - 0.02 14.6 2.7 0.02 14.6 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) HLH PF00010.26 CBY18641.1 - 0.023 14.6 0.4 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain zf-C3HC4_4 PF15227.6 CBY18641.1 - 0.094 12.9 10.1 0.17 12.1 4.6 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING SpoIIE PF07228.12 CBY18641.1 - 0.18 11.7 0.3 11 5.9 0.1 2.1 1 1 1 2 2 2 0 Stage II sporulation protein E (SpoIIE) zf-RING_6 PF14835.6 CBY18641.1 - 0.19 11.6 4.9 0.34 10.8 4.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ATP-synt_E PF05680.12 CBY18641.1 - 0.95 9.8 8.9 0.26 11.6 4.9 1.9 2 0 0 2 2 2 0 ATP synthase E chain Seryl_tRNA_N PF02403.22 CBY18641.1 - 0.97 9.7 12.3 2.1 8.6 12.3 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF87 PF01935.17 CBY18641.1 - 1.5 8.9 7.9 3.5 7.7 7.1 1.8 1 1 1 2 2 2 0 Helicase HerA, central domain DUF2256 PF10013.9 CBY18641.1 - 2.5 8.3 7.0 0.18 11.9 1.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) V_ATPase_I PF01496.19 CBY18641.1 - 3.9 5.3 9.1 4.5 5.1 9.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NOB1_Zn_bind PF08772.11 CBY18641.1 - 6.1 7.1 15.0 0.37 11.0 7.3 2.4 2 1 1 3 3 2 0 Nin one binding (NOB1) Zn-ribbon like Gtr1_RagA PF04670.12 CBY18642.1 - 0.029 13.7 0.2 0.051 12.9 0.2 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region QIL1 PF15884.5 CBY18642.1 - 0.14 12.8 0.0 35 5.1 0.0 3.2 4 0 0 4 4 4 0 MICOS complex subunit MIC13, QIL1 Kelch_1 PF01344.25 CBY18644.1 - 3.3e-06 26.6 0.9 0.1 12.2 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY18644.1 - 0.00049 20.3 0.5 0.024 14.9 0.0 3.2 1 1 2 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CBY18644.1 - 0.00061 19.7 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CBY18644.1 - 0.068 13.5 0.0 9.2 6.7 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY18644.1 - 0.09 12.8 1.2 0.51 10.4 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY18644.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 CBY18645.1 - 5.1e-05 23.2 0.1 0.047 13.7 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY18645.1 - 0.00069 19.8 0.1 0.075 13.3 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CBY18645.1 - 0.0012 19.1 1.2 0.58 10.5 0.1 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY18645.1 - 0.0014 18.6 0.6 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CBY18645.1 - 0.0034 16.9 1.5 0.085 12.5 0.1 2.6 2 1 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CBY18645.1 - 0.035 14.1 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Kelch motif SNF PF00209.18 CBY18648.1 - 2.2e-138 462.2 28.2 2.6e-138 462.0 28.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 7tm_1 PF00001.21 CBY18650.1 - 1.1e-09 38.1 1.1 1.2e-09 37.9 1.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CBY18650.1 - 0.0021 17.5 2.1 0.0024 17.3 2.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 CBY18651.1 - 2.2e-15 56.7 1.2 2.9e-15 56.3 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 CBY18651.1 - 0.019 14.1 6.1 0.012 14.8 3.6 1.7 1 1 1 2 2 2 0 Taste receptor protein (TAS2R) DUF1129 PF06570.11 CBY18651.1 - 0.077 12.5 0.5 0.11 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) YesK PF14150.6 CBY18651.1 - 0.42 10.8 5.1 0.15 12.3 1.3 2.2 2 1 1 3 3 3 0 YesK-like protein DUF5316 PF17247.2 CBY18651.1 - 2.4 8.2 6.3 2.1 8.4 0.3 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5316) TPT PF03151.16 CBY18652.1 - 0.00051 19.5 12.7 0.00062 19.2 12.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Trep_Strep PF09605.10 CBY18652.1 - 0.35 10.8 14.1 0.21 11.5 5.9 2.4 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Homeodomain PF00046.29 CBY18653.1 - 1.3e-20 72.9 1.6 1.3e-20 72.9 1.6 2.2 2 0 0 2 2 2 1 Homeodomain MTBP_N PF14918.6 CBY18654.1 - 0.013 15.0 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 MDM2-binding T2SSM PF04612.12 CBY18654.1 - 0.14 12.2 0.1 0.36 10.9 0.2 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Nucleoporin_FG PF13634.6 CBY18655.1 - 8.5e-11 42.6 59.1 3.6e-07 30.9 30.8 2.8 1 1 1 2 2 2 2 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 CBY18656.1 - 2.7e-54 184.8 30.6 3.8e-54 184.2 30.6 1.2 1 0 0 1 1 1 1 Nucleoporin FG repeated region Spc7 PF08317.11 CBY18656.1 - 0.0017 17.3 3.9 0.0033 16.4 3.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein KxDL PF10241.9 CBY18656.1 - 3.8 7.8 6.4 2.3 8.6 2.4 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein START PF01852.19 CBY18657.1 - 9.1e-21 74.2 0.9 3.7e-20 72.2 0.8 2.1 2 1 0 2 2 2 1 START domain PH PF00169.29 CBY18657.1 - 2.1e-12 47.5 0.2 7.3e-12 45.7 0.2 2.0 1 0 0 1 1 1 1 PH domain DUF5082 PF16888.5 CBY18657.1 - 0.0022 18.2 3.2 0.0022 18.2 3.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) PH_8 PF15409.6 CBY18657.1 - 0.0043 17.3 0.0 0.033 14.5 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 CBY18657.1 - 0.018 15.4 4.7 0.19 12.2 0.3 3.0 2 1 0 3 3 3 0 Pleckstrin homology domain PH_9 PF15410.6 CBY18657.1 - 0.037 14.4 0.0 1.3 9.4 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain VPS53_C PF16854.5 CBY18657.1 - 0.038 13.9 0.2 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus DivIC PF04977.15 CBY18657.1 - 0.05 13.4 3.7 0.32 10.8 0.0 3.0 3 0 0 3 3 3 0 Septum formation initiator AKNA PF12443.8 CBY18657.1 - 0.056 14.1 4.4 0.41 11.3 0.2 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor FAD_binding_6 PF00970.24 CBY18658.1 - 1.6e-27 95.7 0.0 2.7e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBY18658.1 - 5.5e-25 88.1 0.0 8.1e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CBY18658.1 - 8.3e-05 22.8 0.0 0.00016 21.8 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Sds3 PF08598.11 CBY18659.1 - 1.2e-05 25.4 12.4 1.5e-05 25.2 11.7 1.5 1 1 1 2 2 2 1 Sds3-like Exonuc_VII_L PF02601.15 CBY18659.1 - 1.2 8.6 9.3 1.6 8.2 9.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Aldedh PF00171.22 CBY18660.1 - 4.6e-122 407.8 0.1 2e-120 402.5 0.1 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family PseudoU_synth_2 PF00849.22 CBY18660.1 - 0.18 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA pseudouridylate synthase NDUF_B8 PF05821.11 CBY18661.1 - 2.2e-17 63.5 1.7 3.1e-17 63.0 1.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) HK_sensor PF16750.5 CBY18661.1 - 0.47 10.8 1.3 0.95 9.8 1.3 1.4 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase HORMA PF02301.18 CBY18662.1 - 0.00032 20.3 0.1 0.00044 19.9 0.1 1.2 1 0 0 1 1 1 1 HORMA domain ASF1_hist_chap PF04729.13 CBY18663.1 - 2.4e-67 225.7 0.2 3.1e-67 225.3 0.2 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Astacin PF01400.24 CBY18665.1 - 2.3e-17 63.2 0.1 4e-15 55.9 0.1 2.1 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CBY18665.1 - 0.021 14.7 0.7 0.045 13.6 0.7 1.8 1 1 0 1 1 1 0 Matrixin ANAPC4_WD40 PF12894.7 CBY18668.1 - 4e-08 33.4 0.0 7.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain YcxB PF14317.6 CBY18668.1 - 0.13 12.0 0.0 0.43 10.3 0.0 1.8 1 0 0 1 1 1 0 YcxB-like protein Flavi_NS2B PF01002.19 CBY18668.1 - 0.19 11.6 1.4 2.2 8.1 0.7 2.2 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B Peptidase_S39 PF02122.15 CBY18672.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase S39 hEGF PF12661.7 CBY18672.1 - 0.61 10.8 0.2 0.61 10.8 0.2 4.1 3 1 2 5 5 5 0 Human growth factor-like EGF Lectin_C PF00059.21 CBY18673.1 - 4.9e-08 33.7 0.6 1.8e-07 31.8 0.4 2.0 2 0 0 2 2 2 1 Lectin C-type domain Cys_Knot_tox PF17486.2 CBY18673.1 - 0.054 13.7 0.3 0.12 12.7 0.3 1.6 1 0 0 1 1 1 0 Cystine knot toxins Sugar_tr PF00083.24 CBY18675.1 - 5e-30 104.8 4.5 7.1e-30 104.3 4.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY18675.1 - 2.5e-22 79.3 27.1 1.8e-15 56.7 5.2 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.25 CBY18676.1 - 5.2e-60 203.0 0.0 1.1e-59 202.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CBY18676.1 - 2.4e-34 117.3 0.3 3.3e-16 59.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY18676.1 - 1.6e-27 96.5 0.0 3.3e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY18676.1 - 0.00018 21.0 0.0 0.0004 19.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY18676.1 - 0.0025 17.8 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family GlcNAc_2-epim PF07221.11 CBY18677.1 - 5.7e-30 104.7 0.1 9.2e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Phospholip_A2_1 PF00068.19 CBY18678.1 - 4.6e-17 62.5 6.6 4.6e-17 62.5 6.6 2.2 2 0 0 2 2 2 1 Phospholipase A2 PBP_N PF17093.5 CBY18679.1 - 0.13 12.5 4.4 0.25 11.6 4.4 1.5 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Trypan_PARP PF05887.11 CBY18679.1 - 0.4 10.7 9.6 0.76 9.7 9.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) VWD PF00094.25 CBY18680.1 - 3.9e-93 309.9 16.1 9.9e-27 94.1 0.5 13.9 11 2 1 14 14 14 5 von Willebrand factor type D domain C8 PF08742.11 CBY18680.1 - 9.7e-50 166.9 126.1 6.8e-18 64.9 10.5 10.3 9 1 0 9 9 9 5 C8 domain Mucin2_WxxW PF13330.6 CBY18680.1 - 3e-26 92.1 12.8 1.3e-16 61.2 1.7 9.5 8 1 1 9 9 9 2 Mucin-2 protein WxxW repeating region TIL PF01826.17 CBY18680.1 - 1.6e-25 89.1 128.8 5e-10 39.5 17.5 21.4 20 5 3 23 23 23 6 Trypsin Inhibitor like cysteine rich domain zf-C3HC4_3 PF13920.6 CBY18681.1 - 7.3e-07 29.0 6.6 7.3e-07 29.0 6.6 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY18681.1 - 1.6e-06 27.9 9.9 1.6e-06 27.9 9.9 3.2 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY18681.1 - 8e-05 22.4 9.7 8e-05 22.4 9.7 3.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY18681.1 - 0.00014 21.6 8.5 0.00014 21.6 8.5 3.0 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CBY18681.1 - 0.00023 21.4 8.5 0.00023 21.4 8.5 3.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY18681.1 - 0.0016 18.4 11.5 0.002 18.1 4.2 3.6 2 2 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY18681.1 - 0.0024 17.7 12.6 0.0027 17.5 9.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY18681.1 - 0.026 14.4 11.6 0.026 14.4 11.6 3.5 2 2 0 2 2 2 0 Prokaryotic RING finger family 4 DUF3410 PF11890.8 CBY18681.1 - 0.16 11.8 0.4 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Got1 PF04178.12 CBY18683.1 - 1.3e-34 119.0 13.8 1.8e-34 118.5 13.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 CBY18683.1 - 1.4 7.1 9.5 1.7 6.8 9.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) EMP70 PF02990.16 CBY18684.1 - 1.6e-204 680.4 9.6 2.2e-204 680.0 9.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 AAL_decarboxy PF03306.13 CBY18684.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase PA PF02225.22 CBY18685.1 - 7.6e-09 35.5 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 PA domain Arf PF00025.21 CBY18686.1 - 1.6e-77 258.9 0.1 1.8e-77 258.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY18686.1 - 4e-15 56.1 0.1 5.5e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY18686.1 - 5.1e-15 55.4 0.0 6e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CBY18686.1 - 2.8e-11 43.2 0.0 3.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBY18686.1 - 1.1e-10 41.3 1.1 6.2e-07 28.9 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY18686.1 - 9.7e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY18686.1 - 4.5e-06 26.7 0.0 8.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY18686.1 - 0.00022 20.8 0.2 0.0016 18.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CBY18686.1 - 0.0047 16.0 0.4 0.11 11.4 0.1 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CBY18686.1 - 0.0094 16.5 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBY18686.1 - 0.015 15.3 0.2 2.5 8.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CBY18686.1 - 0.019 14.7 0.2 5.4 6.7 0.1 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CBY18686.1 - 0.022 15.3 0.5 0.13 12.8 0.5 1.9 1 1 0 1 1 1 0 ABC transporter cobW PF02492.19 CBY18686.1 - 0.047 13.3 0.3 8.9 5.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CBY18686.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF5595 PF18077.1 CBY18688.1 - 0.0012 18.9 3.4 0.028 14.5 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5595) ATG16 PF08614.11 CBY18688.1 - 0.0066 16.7 3.2 0.0066 16.7 3.2 2.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Miff PF05644.11 CBY18688.1 - 0.011 15.4 0.6 0.011 15.4 0.6 1.8 2 1 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff Cnn_1N PF07989.11 CBY18688.1 - 0.015 15.4 5.4 0.015 15.4 5.4 2.8 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF4763 PF15960.5 CBY18688.1 - 0.024 13.9 8.7 0.69 9.2 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Fez1 PF06818.15 CBY18688.1 - 0.11 12.9 4.7 0.18 12.2 4.7 1.3 1 0 0 1 1 1 0 Fez1 KLRAQ PF10205.9 CBY18688.1 - 0.14 12.4 9.0 0.062 13.5 2.9 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein FapA PF03961.13 CBY18688.1 - 0.15 10.6 3.5 0.28 9.7 3.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A GIT_CC PF16559.5 CBY18688.1 - 0.17 11.8 6.7 0.063 13.1 2.1 2.4 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 CBY18688.1 - 0.67 9.2 5.7 1 8.7 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CBY18688.1 - 1.3 9.1 11.4 0.051 13.7 2.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Lipoprotein_20 PF13942.6 CBY18688.1 - 1.6 8.6 10.0 3.6 7.5 5.3 2.4 1 1 1 2 2 2 0 YfhG lipoprotein FAM76 PF16046.5 CBY18688.1 - 2.9 7.2 11.4 0.14 11.5 5.4 1.9 2 0 0 2 2 2 0 FAM76 protein SlyX PF04102.12 CBY18688.1 - 5.7 7.6 7.1 5.6 7.6 2.4 2.6 1 1 1 2 2 2 0 SlyX Trypsin PF00089.26 CBY18690.1 - 3e-49 167.8 0.6 3e-49 167.8 0.6 1.5 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY18690.1 - 9.5e-05 23.3 0.0 0.00017 22.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY18690.1 - 0.02 15.3 0.1 0.055 13.9 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Hormone_1 PF00103.20 CBY18690.1 - 0.15 11.8 3.1 0.25 11.0 3.1 1.3 1 0 0 1 1 1 0 Somatotropin hormone family Sugar_tr PF00083.24 CBY18691.1 - 1.5e-102 343.8 19.1 1.9e-102 343.5 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY18691.1 - 3.6e-19 68.9 27.3 4.3e-18 65.4 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 CBY18692.1 - 3.1e-34 116.6 0.0 2e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY18692.1 - 3.4e-08 33.1 0.0 1.3e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4497 PF14924.6 CBY18693.1 - 0.056 13.9 0.1 0.081 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) Pentapeptide_3 PF13576.6 CBY18694.1 - 0.0031 17.6 1.4 0.66 10.2 0.4 3.3 3 0 0 3 3 3 2 Pentapeptide repeats (9 copies) Sec62 PF03839.16 CBY18696.1 - 1.9e-29 102.8 4.5 3.3e-29 102.0 4.5 1.6 1 1 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.21 CBY18696.1 - 0.00023 21.2 0.9 0.0006 19.8 0.9 1.7 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_1 PF00036.32 CBY18698.1 - 1.6e-07 30.4 1.3 0.00023 20.5 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY18698.1 - 9.8e-07 28.0 2.9 2.7e-05 23.5 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY18698.1 - 2.3e-06 27.1 2.4 0.0047 16.8 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY18698.1 - 0.00091 19.6 2.6 0.023 15.2 2.6 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY18698.1 - 0.0068 16.2 1.5 0.29 11.0 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair UnbV_ASPIC PF07593.12 CBY18698.1 - 0.073 13.0 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 ASPIC and UnbV UBA PF00627.31 CBY18699.1 - 0.00064 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.10 CBY18699.1 - 0.0086 15.9 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain MS_channel PF00924.18 CBY18699.1 - 0.32 10.5 1.7 0.38 10.3 0.9 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel LRR_8 PF13855.6 CBY18701.1 - 0.055 13.2 1.7 2.5 7.9 0.0 3.0 1 1 2 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 CBY18701.1 - 0.066 13.7 7.2 0.2 12.1 0.2 3.6 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) SYCP2_SLD PF18584.1 CBY18702.1 - 0.046 13.9 1.1 0.23 11.7 0.5 2.4 1 1 1 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain EF-hand_5 PF13202.6 CBY18703.1 - 0.0025 17.2 2.1 0.085 12.4 0.1 3.0 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 CBY18703.1 - 0.016 14.7 4.3 0.15 11.7 0.0 3.2 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 CBY18703.1 - 0.027 14.4 2.5 4.5 7.5 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 CBY18703.1 - 0.27 11.7 4.3 0.67 10.5 0.8 2.8 2 1 1 3 3 3 0 EF-hand domain pair RNA_GG_bind PF10258.9 CBY18704.1 - 5.8e-20 71.1 0.4 1.3e-19 70.0 0.1 1.8 2 0 0 2 2 2 1 PHAX RNA-binding domain DUF4707 PF15806.5 CBY18704.1 - 0.093 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) DUF3287 PF11690.8 CBY18704.1 - 0.16 11.7 1.7 0.19 11.4 0.4 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) DASH_Dad3 PF08656.10 CBY18704.1 - 0.51 10.5 3.9 8.6 6.5 0.0 3.0 3 1 0 3 3 3 0 DASH complex subunit Dad3 DUF3987 PF13148.6 CBY18704.1 - 3.6 6.5 8.0 0.85 8.6 4.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Glycos_transf_2 PF00535.26 CBY18707.1 - 1.5e-25 89.9 0.0 2.4e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CBY18707.1 - 6.2e-06 25.9 0.2 0.016 14.7 0.0 2.9 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 CBY18707.1 - 4.8e-05 23.4 0.0 7.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CBY18707.1 - 0.0002 20.9 0.1 0.00051 19.6 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY18708.1 - 2.3e-25 89.4 0.0 3.9e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY18708.1 - 8.2e-19 68.1 4.6 1.3e-18 67.4 4.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 CBY18708.1 - 1.3e-05 24.8 0.2 0.00032 20.2 0.2 2.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 CBY18708.1 - 7.5e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CBY18708.1 - 0.00023 20.8 3.0 0.00071 19.2 0.1 2.5 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 CBY18708.1 - 0.15 12.8 6.1 2.2 9.1 0.1 3.0 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Pam16 PF03656.13 CBY18709.1 - 5.5e-05 23.2 8.0 6.2e-05 23.0 7.3 1.5 1 1 0 1 1 1 1 Pam16 Indigoidine_A PF04227.12 CBY18709.1 - 0.034 13.5 3.5 0.067 12.5 3.5 1.6 1 1 0 1 1 1 0 Indigoidine synthase A like protein ProSAAS PF07259.12 CBY18709.1 - 4.3 7.3 7.2 1.5 8.7 1.4 2.0 2 0 0 2 2 2 0 ProSAAS precursor MFS_2 PF13347.6 CBY18710.1 - 1.4e-14 53.6 26.3 7.9e-13 47.8 26.3 2.6 1 1 0 1 1 1 1 MFS/sugar transport protein APOBEC3 PF18771.1 CBY18710.1 - 0.12 12.5 0.1 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 APOBEC3 SH3_1 PF00018.28 CBY18711.1 - 2.9e-14 52.4 0.5 2.9e-14 52.4 0.5 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CBY18711.1 - 5.5e-12 45.3 0.1 1.3e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY18711.1 - 8.5e-12 44.6 0.2 2.7e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain RhoGEF PF00621.20 CBY18711.1 - 0.00019 21.7 3.0 0.00021 21.6 0.2 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF5348 PF17295.2 CBY18711.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) FAM76 PF16046.5 CBY18711.1 - 0.05 12.9 0.7 0.11 11.9 0.7 1.6 1 0 0 1 1 1 0 FAM76 protein Cdh1_DBD_1 PF18196.1 CBY18711.1 - 0.18 12.2 4.2 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Rab5-bind PF09311.11 CBY18711.1 - 0.55 9.6 9.4 0.21 10.9 4.3 2.1 2 0 0 2 2 2 0 Rabaptin-like protein Syntaxin-6_N PF09177.11 CBY18711.1 - 0.59 10.7 7.2 1 10.0 2.0 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 CBY18711.1 - 1.7 8.7 9.4 0.088 12.9 2.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Macoilin PF09726.9 CBY18711.1 - 2.9 6.4 11.9 0.64 8.5 7.6 1.8 2 0 0 2 2 2 0 Macoilin family CH PF00307.31 CBY18713.1 - 6.2e-15 55.3 0.1 6.2e-15 55.3 0.1 2.3 2 1 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBY18713.1 - 0.0002 21.2 0.0 0.00065 19.5 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain AvrPto PF11592.8 CBY18713.1 - 0.074 13.1 0.4 0.28 11.2 0.1 2.1 2 0 0 2 2 2 0 Central core of the bacterial effector protein AvrPto DUF5357 PF17310.2 CBY18713.1 - 2.4 6.6 4.4 4.5 5.7 4.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Pkinase PF00069.25 CBY18714.1 - 5e-39 134.2 0.0 8.8e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18714.1 - 3e-28 98.8 0.0 4.8e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY18714.1 - 0.0014 18.0 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY18714.1 - 0.0044 16.4 0.0 0.0095 15.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY18714.1 - 0.0098 14.9 0.1 0.0098 14.9 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBY18714.1 - 0.067 13.1 0.0 0.85 9.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY18714.1 - 0.66 8.7 4.7 0.13 11.0 0.2 2.1 2 1 0 2 2 2 0 Fungal protein kinase Lipase PF00151.19 CBY18715.1 - 3.4e-53 181.1 0.1 4.7e-53 180.6 0.1 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 CBY18715.1 - 0.0015 19.2 0.2 0.002 18.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CBY18715.1 - 0.22 11.4 0.5 0.76 9.6 0.3 2.0 2 1 0 2 2 2 0 Lipase (class 3) CAF1A PF12253.8 CBY18716.1 - 1e-19 70.5 12.5 1e-19 70.5 12.5 8.8 7 2 2 9 9 9 1 Chromatin assembly factor 1 subunit A TPR_12 PF13424.6 CBY18717.1 - 3.8e-17 62.4 44.9 0.0021 18.3 0.4 10.2 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 CBY18717.1 - 3.2e-13 48.9 9.2 0.012 15.4 0.1 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat CHAT PF12770.7 CBY18717.1 - 5.5e-12 45.7 2.6 3e-06 26.9 0.0 3.4 3 1 0 4 4 4 2 CHAT domain TPR_2 PF07719.17 CBY18717.1 - 1.6e-11 43.4 27.0 0.012 15.6 0.2 11.3 13 0 0 13 13 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY18717.1 - 2e-11 43.1 14.7 0.0089 16.2 0.1 10.4 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY18717.1 - 1.6e-10 40.3 16.7 0.0013 18.7 0.2 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_4 PF07721.14 CBY18717.1 - 4.5e-07 29.9 22.4 0.35 11.6 0.4 9.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY18717.1 - 1.1e-05 26.0 33.9 0.0017 19.0 4.3 8.4 8 1 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY18717.1 - 6.4e-05 23.4 38.0 0.19 12.6 0.1 11.7 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY18717.1 - 7.1e-05 22.3 26.2 0.017 14.5 0.1 4.3 1 1 2 3 3 3 2 MalT-like TPR region PhageMin_Tail PF10145.9 CBY18717.1 - 0.00039 20.3 0.4 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 Phage-related minor tail protein SRP_TPR_like PF17004.5 CBY18717.1 - 0.00055 19.9 1.8 0.0044 17.0 0.1 3.2 3 1 0 3 3 3 1 Putative TPR-like repeat ANAPC3 PF12895.7 CBY18717.1 - 0.0018 18.4 32.2 0.0074 16.5 2.2 7.6 7 1 2 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY18717.1 - 0.0074 16.8 0.5 0.0074 16.8 0.5 9.5 8 3 2 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY18717.1 - 0.037 14.4 2.0 0.83 10.2 0.0 4.1 4 0 0 4 4 2 0 Tetratricopeptide repeat Clathrin PF00637.20 CBY18717.1 - 0.046 13.6 9.2 0.87 9.5 2.1 4.0 4 2 1 5 5 4 0 Region in Clathrin and VPS GDH_N PF12466.8 CBY18717.1 - 0.064 13.5 0.1 0.21 11.8 0.1 1.9 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Rapsyn_N PF10579.9 CBY18717.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.6 CBY18717.1 - 0.17 12.6 21.6 0.65 10.8 0.0 8.5 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY18717.1 - 0.61 10.0 33.8 1.2 9.1 0.2 9.9 11 0 0 11 11 10 0 Tetratricopeptide repeat HEAT_2 PF13646.6 CBY18717.1 - 3.1 8.3 18.7 1.8 9.0 0.1 6.3 5 2 3 8 8 7 0 HEAT repeats Ras PF00071.22 CBY18718.1 - 2.7e-67 225.4 1.0 3.3e-67 225.1 1.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY18718.1 - 6.5e-38 129.6 0.1 1.1e-37 128.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY18718.1 - 2.1e-17 63.2 0.2 2.4e-17 62.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY18718.1 - 2.9e-06 26.9 1.7 4.3e-06 26.4 0.3 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY18718.1 - 7.8e-06 25.9 1.5 0.055 13.4 0.2 2.4 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBY18718.1 - 8e-06 25.4 0.1 9.7e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY18718.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBY18718.1 - 2.5e-05 23.8 0.1 3.7e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CBY18718.1 - 0.01 15.3 0.1 0.066 12.7 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 CBY18718.1 - 0.011 15.5 0.1 0.55 10.0 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CBY18718.1 - 0.036 13.6 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 CBY18718.1 - 0.04 14.3 0.0 0.76 10.2 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) LANC_like PF05147.13 CBY18718.1 - 0.041 12.4 0.1 0.09 11.3 0.0 1.5 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein AAA_16 PF13191.6 CBY18718.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CBY18718.1 - 0.058 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 CBY18718.1 - 0.061 12.6 0.1 0.17 11.2 0.0 1.7 1 1 0 1 1 1 0 Septin AAA_5 PF07728.14 CBY18718.1 - 0.094 12.7 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY18718.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 CBY18718.1 - 0.16 11.3 0.0 0.37 10.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein EGF_CA PF07645.15 CBY18720.1 - 7.5e-13 48.5 68.2 7.6e-07 29.2 9.1 5.7 5 0 0 5 5 5 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY18720.1 - 4.1e-05 23.8 52.3 0.19 12.0 8.4 6.1 3 2 1 4 4 4 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CBY18720.1 - 6.8e-05 23.0 54.6 0.00056 20.0 8.1 5.8 5 1 0 5 5 5 3 EGF domain EGF PF00008.27 CBY18720.1 - 0.00025 21.3 47.1 0.0011 19.2 4.9 5.7 4 0 0 4 4 4 4 EGF-like domain cEGF PF12662.7 CBY18720.1 - 0.033 14.1 51.3 0.054 13.4 5.5 7.0 6 0 0 6 6 6 0 Complement Clr-like EGF-like MBG_2 PF18676.1 CBY18720.1 - 0.41 11.3 2.5 1.6 9.4 0.1 3.0 3 0 0 3 3 3 0 MBG domain (YGX type) TRP_2 PF08344.11 CBY18721.1 - 3e-22 78.6 1.5 6.2e-22 77.6 1.5 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 CBY18721.1 - 1.5e-09 38.3 0.2 8.8e-05 23.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY18721.1 - 6.8e-07 29.1 1.7 2 9.2 0.1 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 CBY18721.1 - 0.00048 20.6 0.0 0.045 14.4 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY18721.1 - 0.0065 16.9 0.1 0.42 11.1 0.1 3.1 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CBY18721.1 - 0.014 15.7 0.0 21 5.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Sulfotransfer_1 PF00685.27 CBY18722.1 - 1.1e-07 31.6 0.0 6.9e-07 29.0 0.0 2.3 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY18722.1 - 2.3e-07 31.4 0.0 4.2e-06 27.3 0.0 2.5 1 1 0 1 1 1 1 Sulfotransferase family EGF PF00008.27 CBY18723.1 - 0.00033 20.9 48.6 0.047 14.0 6.1 5.0 4 0 0 4 4 4 3 EGF-like domain EGF_3 PF12947.7 CBY18723.1 - 0.007 16.5 34.6 0.2 11.9 2.5 4.8 4 1 0 4 4 4 3 EGF domain EGF_CA PF07645.15 CBY18723.1 - 0.0083 16.3 11.4 0.0083 16.3 11.4 5.1 3 2 2 5 5 5 1 Calcium-binding EGF domain hEGF PF12661.7 CBY18723.1 - 0.021 15.5 4.4 0.021 15.5 4.4 6.5 6 2 0 6 6 6 0 Human growth factor-like EGF YtxH PF12732.7 CBY18724.1 - 0.033 14.7 0.1 0.044 14.3 0.1 1.4 1 1 0 1 1 1 0 YtxH-like protein Chromo PF00385.24 CBY18725.1 - 2.7e-07 30.4 4.0 3.3e-07 30.1 0.5 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MR_MLE_C PF13378.6 CBY18727.1 - 1.2e-38 132.9 0.0 2.1e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CBY18727.1 - 6.5e-07 29.6 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Spo7 PF03907.13 CBY18729.1 - 0.078 12.4 0.1 0.083 12.4 0.1 1.1 1 0 0 1 1 1 0 Spo7-like protein SNARE PF05739.19 CBY18729.1 - 0.13 12.2 0.2 0.22 11.5 0.2 1.3 1 0 0 1 1 1 0 SNARE domain DUF3328 PF11807.8 CBY18729.1 - 0.15 11.8 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) ASH PF15780.5 CBY18730.1 - 2.5e-53 178.3 41.1 0.0041 17.3 0.0 29.0 31 2 1 32 32 32 11 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CBY18730.1 - 3e-20 72.1 23.3 0.016 15.0 0.0 15.0 17 0 0 17 17 17 6 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBY18730.1 - 6e-19 67.9 21.6 0.65 10.1 0.0 22.0 25 1 0 25 25 25 4 Protein of unknown function (DUF1573) PapD-like PF14874.6 CBY18730.1 - 4.1e-18 65.4 0.5 1.5 9.0 0.0 10.6 11 1 0 11 11 10 4 Flagellar-associated PapD-like MYCBPAP PF14646.6 CBY18730.1 - 5.2e-17 61.9 24.3 0.024 13.6 0.0 13.3 15 0 0 15 15 15 6 MYCBP-associated protein family TMEM131_like PF12371.8 CBY18730.1 - 9e-14 51.5 30.0 1.2 9.5 0.0 16.9 19 0 0 19 19 19 4 Transmembrane protein 131-like Hydin_ADK PF17213.3 CBY18730.1 - 2.3e-07 31.3 26.9 2.6e-07 31.1 0.0 4.3 4 1 1 5 5 5 2 Hydin Adenylate kinase-like domain ADK PF00406.22 CBY18730.1 - 0.0019 18.4 0.6 0.84 9.7 0.8 3.3 2 1 0 2 2 2 1 Adenylate kinase FixG_C PF11614.8 CBY18730.1 - 0.0034 17.6 2.0 17 5.6 0.0 6.7 7 0 0 7 7 7 0 IG-like fold at C-terminal of FixG, putative oxidoreductase SKI PF01202.22 CBY18730.1 - 0.016 15.3 0.0 0.043 13.9 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase AAA_17 PF13207.6 CBY18730.1 - 0.43 11.0 0.0 0.43 11.0 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_18 PF13238.6 CBY18730.1 - 0.85 10.2 3.7 1.3 9.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain MID_MedPIWI PF18296.1 CBY18730.1 - 2.6 7.8 11.4 0.62 9.8 1.5 2.5 2 0 0 2 2 2 0 MID domain of medPIWI C4 PF01413.19 CBY18731.1 - 3.8e-06 27.2 0.0 6.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 CBY18732.1 - 2.6e-114 373.0 463.3 2.1e-09 37.0 27.0 17.3 4 4 10 14 14 14 13 Collagen triple helix repeat (20 copies) C4 PF01413.19 CBY18732.1 - 1.6e-31 109.0 0.5 3e-20 72.6 0.1 2.3 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen PLAC PF08686.11 CBY18733.1 - 1.5e-07 32.0 6.1 1.5e-07 32.0 6.1 3.2 3 0 0 3 3 3 1 PLAC (protease and lacunin) domain TSP_1 PF00090.19 CBY18733.1 - 8e-07 29.2 7.1 8e-07 29.2 7.1 6.1 6 1 0 6 6 6 4 Thrombospondin type 1 domain zf-C2H2 PF00096.26 CBY18734.1 - 5.1e-17 61.3 19.2 7.1e-07 29.3 1.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY18734.1 - 7.8e-11 41.9 17.4 0.003 18.3 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY18734.1 - 9.7e-11 41.6 20.3 1.2e-07 31.8 1.4 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBY18734.1 - 1.4e-05 24.8 5.6 1.4e-05 24.8 5.6 4.3 5 1 0 5 5 4 1 C2H2-type zinc-finger domain DUF3268 PF11672.8 CBY18734.1 - 0.021 15.1 5.3 0.032 14.6 4.3 1.8 1 1 1 2 2 2 0 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 CBY18734.1 - 0.027 14.8 14.3 0.21 11.9 0.1 3.9 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY18734.1 - 0.054 13.5 0.3 0.054 13.5 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_7 PF15269.6 CBY18734.1 - 0.52 10.4 5.7 0.2 11.8 1.2 2.3 1 1 1 2 2 2 0 Zinc-finger SKA1 PF07160.12 CBY18734.1 - 0.61 9.9 0.0 0.61 9.9 0.0 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 zf-C2H2_2 PF12756.7 CBY18734.1 - 0.61 10.5 15.0 73 3.8 0.3 3.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 CBY18734.1 - 1.2 9.3 4.3 4 7.6 1.0 2.6 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 CBY18734.1 - 1.9 8.3 8.9 1.4 8.7 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type DZR PF12773.7 CBY18734.1 - 3.2 7.8 7.6 30 4.7 8.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 CBY18734.1 - 4.6 7.6 13.9 15 6.0 9.9 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Desulfoferrod_N PF06397.12 CBY18734.1 - 9.9 5.9 6.6 60 3.4 0.0 3.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain FYVE PF01363.21 CBY18734.1 - 10 6.4 11.1 23 5.2 0.4 2.5 1 1 1 2 2 2 0 FYVE zinc finger F-box-like PF12937.7 CBY18735.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like Sulfotransfer_2 PF03567.14 CBY18736.1 - 7.4e-10 39.2 4.5 7.4e-10 39.2 4.5 1.8 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY18736.1 - 0.01 15.3 0.3 0.043 13.3 0.3 2.0 1 1 0 1 1 1 0 Sulfotransferase domain DUF2334 PF10096.9 CBY18736.1 - 0.01 15.5 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) PLAC8 PF04749.17 CBY18737.1 - 1e-21 77.8 13.7 1.1e-21 77.6 13.7 1.0 1 0 0 1 1 1 1 PLAC8 family PspB PF06667.12 CBY18738.1 - 0.00019 21.4 1.3 0.00019 21.4 1.3 1.7 2 0 0 2 2 2 1 Phage shock protein B bZIP_1 PF00170.21 CBY18738.1 - 0.0024 17.9 5.4 0.049 13.7 1.0 2.5 2 0 0 2 2 2 1 bZIP transcription factor DUF632 PF04782.12 CBY18738.1 - 0.041 13.2 2.1 5.4 6.2 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF632) Sec2p PF06428.11 CBY18738.1 - 0.052 13.5 4.7 0.087 12.8 1.2 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p TMPIT PF07851.13 CBY18738.1 - 0.057 12.7 2.3 0.068 12.4 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein ADIP PF11559.8 CBY18738.1 - 0.07 13.2 9.5 0.41 10.7 5.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 CBY18738.1 - 0.093 12.3 4.1 0.1 12.1 4.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_2 PF07716.15 CBY18738.1 - 0.12 12.5 11.3 0.096 12.8 3.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Fib_alpha PF08702.10 CBY18738.1 - 0.12 12.6 7.5 0.05 13.8 3.6 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 CBY18738.1 - 0.12 11.7 4.2 0.13 11.6 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 CBY18738.1 - 0.14 12.6 5.7 0.45 11.0 1.4 2.8 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) Wtap PF17098.5 CBY18738.1 - 0.18 11.7 5.1 4.4 7.2 0.2 2.2 1 1 0 2 2 2 0 WTAP/Mum2p family SIR4_SID PF16991.5 CBY18738.1 - 0.19 11.8 2.5 0.23 11.5 2.5 1.2 1 0 0 1 1 1 0 Sir4 SID domain YabA PF06156.13 CBY18738.1 - 0.28 11.8 6.6 6.2 7.5 0.3 2.3 1 1 0 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 CBY18738.1 - 0.39 9.8 5.6 0.42 9.6 5.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 CBY18738.1 - 0.44 10.6 11.4 0.23 11.5 4.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 CBY18738.1 - 0.45 10.7 10.9 1.3 9.3 10.4 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DsrD PF08679.11 CBY18738.1 - 0.51 10.6 3.9 1.2 9.5 0.4 2.3 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Csm1_N PF18504.1 CBY18738.1 - 0.52 10.7 10.2 0.21 11.9 3.0 2.3 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF1664 PF07889.12 CBY18738.1 - 1.3 9.1 4.5 22 5.1 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CBY18738.1 - 3.4 7.5 12.5 8.1 6.3 0.3 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF349 PF03993.12 CBY18738.1 - 3.5 8.0 9.2 0.59 10.5 5.1 1.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF16 PF01519.16 CBY18738.1 - 3.5 8.2 9.8 2.9 8.4 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 CBY18738.1 - 5.8 7.6 8.4 6.6 7.4 0.7 2.9 1 1 1 2 2 2 0 SlyX Cauli_AT PF03233.13 CBY18738.1 - 7.1 6.5 10.6 1.4 8.8 4.0 2.1 1 1 1 2 2 2 0 Aphid transmission protein SSF PF00474.17 CBY18739.1 - 2.5e-06 26.6 5.3 2.5e-06 26.6 5.3 1.6 2 1 0 2 2 2 1 Sodium:solute symporter family Ank_2 PF12796.7 CBY18740.1 - 3.3e-26 91.7 0.0 7.9e-12 45.6 0.0 2.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY18740.1 - 2.8e-24 85.2 0.1 1.8e-07 31.6 0.1 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY18740.1 - 7e-20 70.5 0.1 2.9e-06 27.5 0.0 4.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CBY18740.1 - 4.7e-19 66.5 0.0 1.3e-05 25.2 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBY18740.1 - 5.2e-15 55.3 0.1 1.6e-08 34.6 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF2389 PF09493.10 CBY18740.1 - 0.007 17.0 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Tryptophan-rich protein (DUF2389) Asparaginase PF00710.20 CBY18741.1 - 0.00025 20.7 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal DUF1668 PF07893.13 CBY18741.1 - 0.064 12.6 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) AA_permease_2 PF13520.6 CBY18742.1 - 5e-35 121.2 43.2 6e-35 120.9 43.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY18742.1 - 1.2e-14 53.8 37.6 1.5e-14 53.5 37.6 1.1 1 0 0 1 1 1 1 Amino acid permease Ig_2 PF13895.6 CBY18743.1 - 1.5e-07 31.7 0.0 0.00015 22.1 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 CBY18743.1 - 2e-05 25.1 0.0 0.015 15.9 0.0 3.7 1 1 2 3 3 3 1 Immunoglobulin domain I-set PF07679.16 CBY18743.1 - 0.00047 20.2 0.0 0.16 12.0 0.0 3.0 2 2 0 2 2 2 2 Immunoglobulin I-set domain zf-C3HC4_3 PF13920.6 CBY18744.1 - 0.002 18.0 10.8 0.002 18.0 10.8 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY18744.1 - 0.0056 16.8 11.3 0.0056 16.8 11.3 3.3 4 0 0 4 4 4 1 zinc RING finger of MSL2 DUF1664 PF07889.12 CBY18744.1 - 0.01 15.9 5.0 0.01 15.9 5.0 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) zf-C3HC4_2 PF13923.6 CBY18744.1 - 0.13 12.1 16.2 0.56 10.1 16.2 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CBY18744.1 - 1 9.3 7.6 2.4 8.1 7.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1192 PF06698.11 CBY18744.1 - 1.2 9.2 16.8 1.8 8.6 0.1 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1192) zf-C3HC4 PF00097.25 CBY18744.1 - 4.8 7.1 20.1 1.7 8.6 15.0 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Phospholip_A2_1 PF00068.19 CBY18745.1 - 3.1e-18 66.3 8.0 4.6e-18 65.7 8.0 1.2 1 0 0 1 1 1 1 Phospholipase A2 Baculo_PEP_C PF04513.12 CBY18746.1 - 0.039 14.0 3.7 0.82 9.7 2.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 CBY18746.1 - 0.11 12.8 4.5 0.057 13.7 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Myb_DNA-bind_3 PF12776.7 CBY18746.1 - 0.16 13.0 7.6 2.7 9.0 0.2 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain SlyX PF04102.12 CBY18746.1 - 1.5 9.5 7.3 11 6.8 0.5 2.6 2 1 0 2 2 2 0 SlyX FAM167 PF11652.8 CBY18746.1 - 5.4 7.6 7.5 5.4 7.6 1.7 3.0 1 1 2 3 3 3 0 FAM167 DUF919 PF06034.11 CBY18746.1 - 10 6.1 10.5 1.4 8.8 0.5 3.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Cys_Met_Meta_PP PF01053.20 CBY18747.1 - 2.4e-141 470.7 0.0 2.7e-141 470.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CBY18747.1 - 3.7e-09 36.0 1.0 2.6e-07 29.9 0.3 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Met_gamma_lyase PF06838.11 CBY18747.1 - 1.7e-07 30.1 0.1 4.2e-07 28.8 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 CBY18747.1 - 0.00012 21.3 0.1 0.0002 20.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CBY18747.1 - 0.038 13.3 0.1 0.08 12.2 0.1 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cnd1 PF12717.7 CBY18748.1 - 5.3e-32 111.1 17.6 1.7e-29 103.0 0.1 5.8 5 2 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBY18748.1 - 8.4e-10 37.8 11.9 0.0016 17.1 0.1 5.8 3 3 1 5 5 5 5 Adaptin N terminal region Cnd3 PF12719.7 CBY18748.1 - 0.027 13.7 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain PqqD PF05402.12 CBY18748.1 - 0.24 11.7 3.9 0.79 10.1 0.0 3.6 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) GHL10 PF02638.15 CBY18749.1 - 5.7e-63 212.9 2.5 7.9e-63 212.4 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GHL6 PF14871.6 CBY18749.1 - 0.048 13.8 0.0 8.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Cas9_a PF18470.1 CBY18749.1 - 0.14 11.7 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Cas9 alpha-helical lobe domain SLY PF12485.8 CBY18750.1 - 0.064 14.0 0.0 0.073 13.8 0.0 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Gal_Lectin PF02140.18 CBY18752.1 - 4.9e-13 49.3 1.7 1.9e-12 47.4 0.9 2.3 2 0 0 2 2 2 1 Galactose binding lectin domain Phospholip_A2_1 PF00068.19 CBY18753.1 - 5.1e-12 46.2 10.5 5.1e-12 46.2 10.5 2.1 2 1 0 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.12 CBY18753.1 - 2.9 8.5 6.0 6.5 7.4 6.0 1.5 1 0 0 1 1 1 0 Poxvirus A21 Protein Raffinose_syn PF05691.12 CBY18754.1 - 5.6e-05 21.2 0.0 7.1e-05 20.8 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Bac_rhamnosid_C PF17390.2 CBY18754.1 - 0.051 13.4 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain Ifi-6-16 PF06140.13 CBY18755.1 - 2.6e-11 43.3 30.9 3.8e-11 42.7 30.9 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ribosomal_60s PF00428.19 CBY18756.1 - 5.5e-20 71.8 8.7 6.4e-20 71.5 8.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_transf_22 PF03901.17 CBY18757.1 - 5.7e-34 118.1 14.2 7e-34 117.8 14.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PHO4 PF01384.20 CBY18757.1 - 0.95 8.4 2.7 2.3 7.2 2.4 1.4 1 1 0 1 1 1 0 Phosphate transporter family MA3 PF02847.17 CBY18758.1 - 0.0075 16.2 0.7 0.017 15.1 0.7 1.5 1 0 0 1 1 1 1 MA3 domain DUF1542 PF07564.11 CBY18758.1 - 0.014 15.4 2.8 0.052 13.7 2.8 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Cryptochrome_C PF12546.8 CBY18758.1 - 0.11 13.1 0.6 0.11 13.1 0.6 2.6 2 1 0 3 3 3 0 Blue/Ultraviolet sensing protein C terminal Tox-ODYAM1 PF15642.6 CBY18758.1 - 0.19 10.7 4.8 0.25 10.3 4.8 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus RNR_Alpha PF17975.1 CBY18758.1 - 0.26 11.8 2.8 0.67 10.5 1.3 2.2 1 1 1 2 2 2 0 Ribonucleotide reductase alpha domain DUF3492 PF11997.8 CBY18758.1 - 0.83 9.3 5.0 1.4 8.6 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) BCAS2 PF05700.11 CBY18759.1 - 4.8e-69 232.2 8.2 5.7e-69 231.9 8.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) SbcD_C PF12320.8 CBY18759.1 - 0.0025 18.1 5.2 0.045 14.1 2.8 2.3 1 1 1 2 2 2 1 Type 5 capsule protein repressor C-terminal domain Rab5-bind PF09311.11 CBY18759.1 - 0.009 15.4 7.1 0.018 14.5 7.1 1.5 1 0 0 1 1 1 1 Rabaptin-like protein DUF3271 PF11675.8 CBY18759.1 - 0.025 13.8 3.1 0.36 10.0 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3271) CENP-F_leu_zip PF10473.9 CBY18759.1 - 0.048 13.7 8.7 2.7 8.0 7.0 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Helo_like_N PF17111.5 CBY18759.1 - 0.055 12.8 3.4 0.084 12.2 2.1 1.8 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins HR1 PF02185.16 CBY18759.1 - 0.075 13.2 5.9 0.31 11.2 5.9 2.2 1 1 0 1 1 1 0 Hr1 repeat Rootletin PF15035.6 CBY18759.1 - 0.11 12.5 12.2 0.05 13.6 9.3 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1515 PF07439.11 CBY18759.1 - 0.15 12.1 1.1 0.28 11.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Exonuc_VII_L PF02601.15 CBY18759.1 - 0.25 10.9 4.6 0.29 10.6 4.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med9 PF07544.13 CBY18759.1 - 0.34 11.0 6.8 4 7.6 0.0 3.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4810 PF16068.5 CBY18759.1 - 0.47 11.0 3.4 18 6.0 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4810) ZapB PF06005.12 CBY18759.1 - 0.71 10.4 14.1 6.9 7.2 3.1 3.4 2 2 1 3 3 3 0 Cell division protein ZapB LMBR1 PF04791.16 CBY18759.1 - 1.1 8.1 4.0 1.2 7.9 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Csm1_N PF18504.1 CBY18759.1 - 1.1 9.6 10.7 0.066 13.6 3.8 2.5 2 1 1 3 3 3 0 Csm1 N-terminal domain KxDL PF10241.9 CBY18759.1 - 2.7 8.3 8.0 11 6.3 0.5 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein SlyX PF04102.12 CBY18759.1 - 4.2 8.1 8.9 3.6 8.3 6.5 2.2 1 1 1 2 2 2 0 SlyX CCDC-167 PF15188.6 CBY18759.1 - 7.6 7.0 8.3 1.9 8.9 1.3 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 PRKG1_interact PF15898.5 CBY18759.1 - 7.6 7.5 10.5 1.6 9.7 5.7 2.1 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain GIT_CC PF16559.5 CBY18759.1 - 8.8 6.3 10.5 21 5.1 6.6 2.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Indigoidine_A PF04227.12 CBY18760.1 - 1.6e-109 365.7 0.1 1.9e-109 365.6 0.1 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein RRM_1 PF00076.22 CBY18761.1 - 1.4e-15 56.8 0.9 3.1e-08 33.3 0.1 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY18761.1 - 6.5e-06 25.9 0.3 0.16 11.9 0.0 3.5 2 2 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CBY18761.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif NPR3 PF03666.13 CBY18761.1 - 4.5 6.0 17.2 0.49 9.1 10.1 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 LRR_8 PF13855.6 CBY18763.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeat Staphostatin_A PF09022.10 CBY18763.1 - 0.18 11.7 0.1 2.4 8.1 0.0 2.6 3 0 0 3 3 3 0 Staphostatin A Nfu_N PF08712.11 CBY18764.1 - 6.3e-28 96.7 0.0 8.6e-28 96.2 0.0 1.2 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CBY18765.1 - 4.2e-25 87.7 0.0 6.4e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Pkinase PF00069.25 CBY18766.1 - 4.2e-47 160.7 0.0 6.3e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18766.1 - 9.9e-30 103.7 0.0 1.9e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY18766.1 - 4.3e-05 23.0 0.0 0.00027 20.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like SPOB_a PF14689.6 CBY18767.1 - 8.5 6.2 7.9 2.8 7.7 0.1 3.4 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain ACBP PF00887.19 CBY18768.1 - 1.7e-29 101.9 0.5 1.8e-29 101.7 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.32 CBY18769.1 - 3.4e-45 151.1 33.1 3.5e-07 30.8 0.3 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 CBY18769.1 - 1.3e-13 50.6 0.9 2.3e-13 49.8 0.9 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CBY18769.1 - 1.6e-11 44.4 7.0 0.1 12.9 0.0 6.5 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CBY18769.1 - 3e-11 42.9 0.3 6.9e-11 41.7 0.3 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 CBY18769.1 - 2.6e-07 29.7 17.5 0.018 13.7 0.6 6.0 3 2 3 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CBY18769.1 - 1.6e-05 24.6 7.4 0.0044 16.6 2.3 3.4 2 2 0 2 2 2 2 PQQ-like domain FAM83 PF07894.12 CBY18769.1 - 0.011 15.3 0.0 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 FAM83 A-H DUF5046 PF16465.5 CBY18769.1 - 0.081 12.4 0.4 9.5 5.6 0.1 3.2 1 1 2 4 4 4 0 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 CBY18769.1 - 0.12 12.9 4.7 11 6.6 0.0 5.2 6 2 1 7 7 7 0 PQQ-like domain NADHdh PF00146.21 CBY18770.1 - 0.0033 16.8 0.6 0.0033 16.8 0.6 1.1 1 0 0 1 1 1 1 NADH dehydrogenase Amidase PF01425.21 CBY18771.1 - 0.16 10.9 0.6 0.24 10.3 0.6 1.2 1 0 0 1 1 1 0 Amidase EMC3_TMCO1 PF01956.16 CBY18771.1 - 0.19 11.4 3.2 0.38 10.5 3.2 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SOBP PF15279.6 CBY18771.1 - 0.26 11.8 8.8 0.39 11.3 8.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Sec62 PF03839.16 CBY18771.1 - 1.7 8.1 8.6 3.1 7.3 8.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Sulfotransfer_4 PF17784.1 CBY18772.1 - 4.9e-61 206.3 0.0 6.1e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY18772.1 - 0.024 15.0 0.1 0.18 12.2 0.0 2.4 2 2 1 3 3 3 0 Sulfotransferase family DPBB_1 PF03330.18 CBY18773.1 - 0.00032 20.9 1.7 0.00046 20.4 0.3 2.0 2 0 0 2 2 2 1 Lytic transglycolase Zn-ribbon_8 PF09723.10 CBY18775.1 - 0.89 9.7 3.2 2 8.6 3.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain eRF1_2 PF03464.15 CBY18776.1 - 1e-43 148.8 0.3 2.8e-43 147.4 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 CBY18776.1 - 2.8e-33 114.8 0.0 6.3e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CBY18776.1 - 2.6e-20 72.7 0.0 4.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 CBY18776.1 - 1.5e-07 31.8 0.0 2.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 CBY18776.1 - 2.7e-07 31.0 0.0 4.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ssl1 PF04056.14 CBY18776.1 - 0.01 15.7 0.0 0.043 13.6 0.0 2.1 1 1 1 2 2 2 0 Ssl1-like VWA_2 PF13519.6 CBY18776.1 - 0.1 13.2 0.0 18 6.0 0.0 2.8 1 1 1 2 2 2 0 von Willebrand factor type A domain DUF2053 PF09767.9 CBY18777.1 - 4.1e-49 166.8 4.7 6.6e-49 166.1 4.7 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) SpvB PF03534.13 CBY18778.1 - 0.062 12.5 0.1 0.075 12.2 0.1 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein WD40 PF00400.32 CBY18780.1 - 0.091 13.7 7.1 4.2 8.4 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat mRNA_cap_enzyme PF01331.19 CBY18781.1 - 5.8e-62 209.0 0.0 1e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CBY18781.1 - 1.2e-20 74.1 0.0 2.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 CBY18781.1 - 1.8e-10 40.7 0.0 4.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 CBY18781.1 - 0.0073 16.0 0.0 0.26 10.9 0.0 2.5 1 1 1 2 2 2 1 ATP dependent DNA ligase domain FAD-oxidase_C PF02913.19 CBY18782.1 - 1.2e-44 152.9 0.0 1.6e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBY18782.1 - 5.8e-20 71.5 0.1 1.7e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain AMP-binding PF00501.28 CBY18783.1 - 2e-12 46.4 0.0 3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CBY18784.1 - 2.3e-28 98.9 0.0 2.9e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TSP_1 PF00090.19 CBY18785.1 - 3.1e-88 289.8 245.3 7.2e-09 35.7 8.7 13.7 14 0 0 14 14 14 13 Thrombospondin type 1 domain zf-ZPR1 PF03367.13 CBY18786.1 - 0.0011 18.9 0.5 0.0022 17.8 0.5 1.5 1 0 0 1 1 1 1 ZPR1 zinc-finger domain Lectin_C PF00059.21 CBY18786.1 - 0.007 17.1 0.9 3.2 8.5 0.9 2.7 1 1 0 1 1 1 1 Lectin C-type domain DNA_topoisoIV PF00521.20 CBY18786.1 - 0.05 12.5 5.2 0.37 9.6 5.3 2.1 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF2433 PF10360.9 CBY18786.1 - 0.31 11.2 1.7 1.4 9.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) PARM PF17061.5 CBY18787.1 - 0.13 12.4 6.3 0.25 11.4 6.3 1.4 1 0 0 1 1 1 0 PARM p47_phox_C PF08944.11 CBY18787.1 - 6.2 6.3 6.9 0.21 11.0 0.8 1.7 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain RVT_1 PF00078.27 CBY18788.1 - 6.5e-26 91.2 0.0 1.5e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CBY18788.1 - 0.00016 21.5 0.8 0.0005 19.9 0.1 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_E_G PF10150.9 CBY18788.1 - 0.025 14.0 8.7 0.014 14.8 3.3 2.9 2 0 0 2 2 2 0 Ribonuclease E/G family Exo_endo_phos PF03372.23 CBY18788.1 - 0.031 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FAIM1 PF06905.13 CBY18790.1 - 0.0099 15.6 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) DUF4701 PF15773.5 CBY18791.1 - 0.28 10.1 7.9 0.33 9.9 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) Herpes_capsid PF06112.11 CBY18791.1 - 0.32 11.1 11.2 0.4 10.7 11.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sporozoite_P67 PF05642.11 CBY18791.1 - 0.34 9.0 7.4 0.35 8.9 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 CBY18791.1 - 0.46 10.5 22.5 0.56 10.2 22.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FAM199X PF15814.5 CBY18791.1 - 0.62 9.1 6.1 0.69 8.9 6.1 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF2057 PF09829.9 CBY18791.1 - 0.63 10.2 8.3 0.77 9.9 8.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) FSA_C PF10479.9 CBY18791.1 - 1.1 7.2 15.4 1.3 7.1 15.4 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 CBY18791.1 - 1.6 6.9 19.7 1.9 6.6 19.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glycoprotein PF03409.15 CBY18791.1 - 2.4 6.9 10.9 2.6 6.8 10.9 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein PepSY_like PF11396.8 CBY18792.1 - 0.58 10.8 3.3 5.5 7.6 0.1 2.5 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like Pkinase PF00069.25 CBY18793.1 - 7.1e-49 166.5 0.0 1.5e-48 165.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18793.1 - 9.4e-32 110.3 0.0 1.8e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY18793.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APG6_N PF17675.1 CBY18793.1 - 0.0077 16.8 5.7 0.0077 16.8 5.7 2.6 3 0 0 3 3 3 1 Apg6 coiled-coil region DUF3050 PF11251.8 CBY18793.1 - 0.096 12.3 3.0 0.24 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3050) Sulfate_transp PF00916.20 CBY18794.1 - 6.4e-93 311.5 18.1 2e-91 306.6 18.1 2.1 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CBY18794.1 - 4.2e-09 36.1 0.0 2.1e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 CBY18794.1 - 0.0089 16.4 3.9 0.0089 16.4 3.9 3.0 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily RNA_replicase_B PF03431.13 CBY18795.1 - 0.0053 15.3 0.8 0.01 14.3 0.4 1.6 1 1 0 1 1 1 1 RNA replicase, beta-chain Tox-REase-5 PF15648.6 CBY18795.1 - 0.077 13.5 2.1 0.83 10.2 0.3 2.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 HALZ PF02183.18 CBY18795.1 - 0.079 13.2 0.6 0.079 13.2 0.6 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper EF1G PF00647.19 CBY18795.1 - 0.08 13.0 2.8 0.35 10.9 0.5 2.4 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain DASH_Dam1 PF08653.10 CBY18795.1 - 0.25 11.2 2.9 14 5.6 0.2 3.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 Cep57_CLD_2 PF14197.6 CBY18795.1 - 4.8 7.4 25.4 9 6.5 1.5 4.2 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 UPF0047 PF01894.17 CBY18797.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 LSM_int_assoc PF16605.5 CBY18797.1 - 4.4 7.5 10.0 0.073 13.2 0.7 2.9 3 0 0 3 3 3 0 LSM-interacting associated unstructured Kin17_mid PF10357.9 CBY18799.1 - 4.7e-41 139.6 2.6 4.7e-41 139.6 2.6 2.2 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CBY18799.1 - 1.6e-06 28.1 2.9 1.9e-05 24.7 0.5 2.6 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 CBY18799.1 - 0.027 14.9 5.2 0.027 14.9 5.2 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY18799.1 - 6.9 7.1 14.0 0.058 13.7 5.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EMC1_C PF07774.13 CBY18800.1 - 4.2e-56 190.0 0.0 8.4e-56 189.0 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CBY18800.1 - 0.0036 16.9 0.1 0.57 9.7 0.0 3.2 4 0 0 4 4 4 2 PQQ-like domain PLAC8 PF04749.17 CBY18801.1 - 1.2e-16 61.5 9.2 1.6e-16 61.1 9.2 1.2 1 0 0 1 1 1 1 PLAC8 family Mob1_phocein PF03637.17 CBY18802.1 - 1.8e-58 197.3 0.3 2.2e-58 197.0 0.3 1.1 1 0 0 1 1 1 1 Mob1/phocein family PHD PF00628.29 CBY18803.1 - 2e-08 34.0 4.1 4.4e-08 32.9 4.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY18803.1 - 7.3e-05 22.2 4.3 0.00014 21.3 4.3 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 CBY18803.1 - 0.051 13.5 1.0 0.14 12.0 1.0 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_10 PF10058.9 CBY18803.1 - 0.14 11.9 1.5 0.39 10.5 1.5 1.8 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-CSL PF05207.13 CBY18803.1 - 0.58 9.9 2.6 2.5 7.9 2.6 2.1 1 1 0 1 1 1 0 CSL zinc finger TPD PF14811.6 CBY18804.1 - 2.8 7.8 6.3 29 4.5 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function TPD sequence-motif WD40 PF00400.32 CBY18805.1 - 1.7e-23 82.4 17.3 0.00031 21.5 0.5 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PNPase_C PF12111.8 CBY18805.1 - 0.013 14.9 0.6 0.031 13.7 0.6 1.7 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal Coatomer_WDAD PF04053.14 CBY18805.1 - 0.029 13.4 0.3 0.16 11.0 0.3 2.0 1 1 0 1 1 1 0 Coatomer WD associated region Fib_alpha PF08702.10 CBY18805.1 - 0.055 13.7 0.7 0.11 12.6 0.7 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 CBY18805.1 - 0.27 11.9 1.8 0.91 10.2 1.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Kelch_1 PF01344.25 CBY18806.1 - 9.5e-60 198.0 9.1 1.4e-13 50.1 0.0 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBY18806.1 - 1.6e-33 113.9 0.5 1.2e-05 25.5 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BTB PF00651.31 CBY18806.1 - 8.6e-23 80.7 0.1 1.6e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 CBY18806.1 - 2.6e-20 71.6 0.5 8.2e-05 22.4 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 CBY18806.1 - 4.2e-20 71.5 0.3 0.0052 16.8 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY18806.1 - 1.3e-19 70.0 0.3 8.3e-05 22.8 0.0 6.9 6 1 0 6 6 6 4 Galactose oxidase, central domain BACK PF07707.15 CBY18806.1 - 4.5e-17 62.0 4.4 1.4e-16 60.5 2.7 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CBY18806.1 - 1.3e-10 41.0 3.8 0.0017 18.3 0.0 5.2 5 0 0 5 5 5 3 Kelch motif ATP_bind_1 PF03029.17 CBY18807.1 - 6.8e-84 281.4 0.2 7.9e-84 281.2 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CBY18807.1 - 0.004 17.0 0.0 0.035 13.9 0.0 2.4 2 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 CBY18807.1 - 0.0094 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.6 CBY18807.1 - 0.012 15.9 0.0 0.039 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBY18807.1 - 0.014 15.2 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY18807.1 - 0.021 15.4 0.3 0.089 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBY18807.1 - 0.047 13.9 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY18807.1 - 0.064 13.7 0.0 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 CBY18807.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 CBY18807.1 - 0.098 12.6 0.0 17 5.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBY18807.1 - 0.11 11.7 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 CBY18807.1 - 0.12 12.4 0.1 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 CBY18807.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CBY18807.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Abhydrolase_6 PF12697.7 CBY18809.1 - 2.5e-26 93.6 0.0 3.3e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBY18809.1 - 3.5e-12 46.1 0.0 7.4e-12 45.0 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY18809.1 - 6.6e-10 39.1 0.1 7.9e-09 35.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CBY18809.1 - 5.4e-06 26.7 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 CBY18809.1 - 0.0076 16.0 0.6 0.016 14.9 0.1 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.16 CBY18809.1 - 0.011 15.6 0.2 0.45 10.3 0.0 2.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CBY18809.1 - 0.021 14.7 0.2 0.078 12.8 0.2 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 CBY18809.1 - 0.024 14.2 0.0 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.25 CBY18809.1 - 0.077 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 CBY18809.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF4663 PF15668.5 CBY18810.1 - 7.2e-17 61.5 0.0 8e-11 41.6 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4663) Tubulin PF00091.25 CBY18811.1 - 5.5e-69 232.3 0.0 7.6e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY18811.1 - 7e-52 174.9 0.0 1.1e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY18811.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Comm PF15957.5 CBY18812.1 - 0.081 13.3 1.0 0.095 13.1 1.0 1.1 1 0 0 1 1 1 0 Commissureless DUF2681 PF10883.8 CBY18812.1 - 0.14 12.6 0.4 0.2 12.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Tetraspanin PF00335.20 CBY18813.1 - 3.9e-09 36.6 1.5 4.6e-09 36.3 1.5 1.1 1 0 0 1 1 1 1 Tetraspanin family ATP-synt_C PF00137.21 CBY18814.1 - 2e-10 40.8 12.9 3.7e-10 40.0 12.9 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Ets PF00178.22 CBY18815.1 - 1.9e-31 108.3 0.2 1.9e-31 108.3 0.2 1.9 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 CBY18815.1 - 3.7e-14 52.5 0.1 6.7e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain AKNA PF12443.8 CBY18816.1 - 0.012 16.2 0.4 0.018 15.7 0.4 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor KIP1 PF07765.12 CBY18816.1 - 0.059 13.5 2.4 5.4 7.2 0.2 2.3 2 0 0 2 2 2 0 KIP1-like protein FBP_C PF16571.5 CBY18816.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger NAM PF02365.15 CBY18817.1 - 0.0055 17.6 0.5 0.0071 17.3 0.5 1.2 1 0 0 1 1 1 1 No apical meristem (NAM) protein MadM PF03818.13 CBY18818.1 - 0.57 10.1 4.3 1.3 8.9 0.1 2.7 3 1 0 3 3 3 0 Malonate/sodium symporter MadM subunit CutC PF03932.14 CBY18819.1 - 9.5e-45 152.6 0.1 1.2e-44 152.2 0.1 1.1 1 0 0 1 1 1 1 CutC family TMP-TENI PF02581.17 CBY18819.1 - 2.2e-05 23.8 0.2 0.00014 21.3 0.0 2.2 3 0 0 3 3 3 1 Thiamine monophosphate synthase His_biosynth PF00977.21 CBY18819.1 - 0.00025 20.6 0.0 0.051 13.0 0.0 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 CBY18819.1 - 0.0014 18.0 0.1 0.019 14.4 0.0 2.3 2 0 0 2 2 2 1 Ribulose-phosphate 3 epimerase family AP_endonuc_2 PF01261.24 CBY18819.1 - 0.016 14.7 0.0 0.14 11.6 0.0 2.2 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel QRPTase_C PF01729.19 CBY18819.1 - 0.017 14.9 0.1 0.32 10.8 0.0 2.4 2 1 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF745 PF05335.13 CBY18820.1 - 0.0092 15.7 1.5 0.0092 15.7 1.5 5.5 3 1 2 6 6 6 1 Protein of unknown function (DUF745) ThrE PF06738.12 CBY18820.1 - 1.2 8.4 9.6 0.066 12.6 0.8 3.0 3 0 0 3 3 3 0 Putative threonine/serine exporter SAM_2 PF07647.17 CBY18821.1 - 0.0021 18.1 0.1 0.0042 17.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ATP-synt_D PF01813.17 CBY18822.1 - 1.8e-71 240.0 0.9 1.8e-71 240.0 0.9 1.6 2 0 0 2 2 2 1 ATP synthase subunit D HECT PF00632.25 CBY18823.1 - 5.2e-61 206.8 0.0 8.4e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.8 CBY18823.1 - 4.1e-14 52.0 0.1 9.8e-14 50.8 0.1 1.6 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD PABP PF00658.18 CBY18823.1 - 3e-08 33.7 0.2 9.5e-08 32.1 0.2 1.9 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain zf-UBR PF02207.20 CBY18823.1 - 5.8e-05 23.2 23.0 5.8e-05 23.2 23.0 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Ank_2 PF12796.7 CBY18823.1 - 0.087 13.4 0.0 0.39 11.3 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) ATG13 PF10033.9 CBY18824.1 - 1.3e-08 34.9 1.5 1.4e-05 24.9 0.7 2.8 1 1 1 2 2 2 2 Autophagy-related protein 13 Thiolase_N PF00108.23 CBY18825.1 - 7.7e-38 130.3 0.4 1.8e-36 125.9 0.1 2.0 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY18825.1 - 4.6e-37 126.4 0.4 1e-36 125.3 0.3 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain Latrotoxin_C PF15658.6 CBY18825.1 - 0.051 13.3 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Latrotoxin C-terminal domain DSL PF01414.19 CBY18826.1 - 4.5e-10 39.7 1.5 4.5e-10 39.7 1.5 4.0 3 1 1 4 4 4 1 Delta serrate ligand EGF_2 PF07974.13 CBY18826.1 - 0.01 16.2 11.5 0.01 16.2 11.5 4.3 5 0 0 5 5 5 0 EGF-like domain cEGF PF12662.7 CBY18826.1 - 0.22 11.5 5.2 6.7 6.8 1.8 3.5 2 0 0 2 2 2 0 Complement Clr-like EGF-like hEGF PF12661.7 CBY18826.1 - 3.9 8.3 23.3 0.16 12.7 7.3 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF Vps36-NZF-N PF16988.5 CBY18827.1 - 0.55 9.7 7.0 0.11 12.0 2.7 2.0 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Elf1 PF05129.13 CBY18827.1 - 0.79 9.8 5.5 0.18 11.9 1.2 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like EF-hand_1 PF00036.32 CBY18829.1 - 2.4e-11 42.3 8.2 2e-05 23.8 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 CBY18829.1 - 2.5e-10 40.6 11.4 8.4e-08 32.6 1.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY18829.1 - 1e-09 37.5 6.3 0.00099 18.9 0.0 4.6 4 1 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY18829.1 - 1.1e-09 37.3 4.5 0.00012 21.4 0.1 3.7 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 CBY18829.1 - 2.9e-05 24.4 10.2 0.01 16.1 3.9 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.11 CBY18829.1 - 0.0008 19.8 0.5 1 9.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand Dockerin_1 PF00404.18 CBY18829.1 - 0.0063 16.7 0.4 0.36 11.1 0.1 3.0 2 1 1 3 3 3 2 Dockerin type I domain EF-hand_8 PF13833.6 CBY18829.1 - 0.0065 16.3 6.6 3.2 7.7 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair MTCP1 PF08991.10 CBY18830.1 - 0.0008 19.6 2.3 0.0018 18.5 2.3 1.6 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 CBY18830.1 - 0.00095 19.2 3.4 0.0016 18.6 3.4 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CBY18830.1 - 0.031 14.3 1.5 0.057 13.4 1.5 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 CBY18830.1 - 0.58 9.9 3.9 0.2 11.4 1.1 1.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) HGTP_anticodon PF03129.20 CBY18832.1 - 7.8e-14 51.6 0.0 2.6e-13 49.9 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBY18832.1 - 1.1e-12 48.2 0.8 5.5e-12 46.0 0.8 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 CBY18832.1 - 0.18 12.0 3.7 0.47 10.6 3.7 1.7 1 0 0 1 1 1 0 WHEP-TRS domain WD40 PF00400.32 CBY18833.1 - 1e-13 51.5 8.3 0.00017 22.3 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY18833.1 - 6.2e-10 39.3 4.8 0.00059 20.1 0.4 4.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY18833.1 - 1.9e-05 24.7 0.4 0.15 11.9 0.0 3.3 1 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A INTS5_N PF14837.6 CBY18834.1 - 2.6e-36 125.2 0.6 2.6e-36 125.2 0.6 2.8 3 0 0 3 3 3 1 Integrator complex subunit 5 N-terminus INTS5_C PF14838.6 CBY18834.1 - 1.7e-27 96.5 15.0 1.7e-27 96.4 4.7 2.3 1 1 1 2 2 2 2 Integrator complex subunit 5 C-terminus N2227 PF07942.12 CBY18834.1 - 0.084 12.1 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 N2227-like protein GGA_N-GAT PF18308.1 CBY18834.1 - 0.2 11.3 5.0 0.13 11.9 0.3 3.0 3 0 0 3 3 3 0 GGA N-GAT domain MRP-S32 PF10210.9 CBY18835.1 - 7.6e-05 23.2 0.3 0.00017 22.1 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S32 DUF4078 PF13300.6 CBY18836.1 - 3.1e-14 53.1 4.4 3.1e-14 53.1 4.4 5.0 3 3 1 4 4 4 1 Domain of unknown function (DUF4078) B9-C2 PF07162.11 CBY18838.1 - 6.5e-27 94.8 0.0 1e-26 94.2 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4106 PF13388.6 CBY18839.1 - 0.62 9.2 10.6 0.98 8.6 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TFIIA PF03153.13 CBY18839.1 - 1.7 8.6 10.8 2.3 8.1 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arf PF00025.21 CBY18840.1 - 1.1e-66 223.6 0.1 1.2e-66 223.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBY18840.1 - 1.7e-15 57.0 0.0 2e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY18840.1 - 3.9e-15 55.9 0.4 2.2e-09 37.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CBY18840.1 - 1.3e-14 54.5 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBY18840.1 - 2.8e-14 53.0 0.0 3.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBY18840.1 - 8.7e-14 51.3 0.0 1.8e-13 50.3 0.0 1.4 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY18840.1 - 7.5e-08 32.4 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY18840.1 - 8.6e-05 22.2 0.0 0.00031 20.3 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CBY18840.1 - 0.00048 19.6 0.0 0.0027 17.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein MeaB PF03308.16 CBY18840.1 - 0.0042 16.1 0.1 0.85 8.5 0.1 2.4 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1_Xtn PF16897.5 CBY18840.1 - 0.0089 16.0 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain CdhD PF03599.16 CBY18840.1 - 0.012 14.3 0.0 0.045 12.5 0.0 1.7 1 1 1 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit PduV-EutP PF10662.9 CBY18840.1 - 0.077 12.7 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 CBY18840.1 - 0.1 13.1 0.1 0.16 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY18840.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 CBY18840.1 - 0.11 12.0 0.7 0.67 9.5 0.7 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B DCX PF03607.17 CBY18841.1 - 1.6e-16 60.1 0.1 1.6e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Doublecortin Connexin43 PF03508.13 CBY18841.1 - 0.21 11.2 0.9 0.69 9.5 0.9 1.9 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) DUF1481 PF07356.12 CBY18844.1 - 0.022 14.6 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) Corona_NS2A PF05213.12 CBY18846.1 - 0.034 13.5 0.0 0.047 13.0 0.0 1.4 1 1 0 1 1 1 0 Coronavirus NS2A protein His_Phos_1 PF00300.22 CBY18847.1 - 1.1e-27 97.0 0.0 3e-27 95.6 0.0 1.6 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) Ion_trans_2 PF07885.16 CBY18848.1 - 1.4e-29 101.9 21.5 2.5e-16 59.4 4.2 3.3 3 0 0 3 3 3 3 Ion channel IRK PF01007.20 CBY18848.1 - 0.00043 20.1 1.0 0.49 10.2 0.4 2.5 2 0 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain Death PF00531.22 CBY18848.1 - 0.19 11.9 0.1 0.43 10.8 0.1 1.5 1 0 0 1 1 1 0 Death domain TSP_1 PF00090.19 CBY18849.1 - 4.5e-08 33.2 6.1 4.5e-08 33.2 6.1 2.1 3 0 0 3 3 3 1 Thrombospondin type 1 domain HMMR_C PF15908.5 CBY18851.1 - 0.016 15.5 0.8 0.023 14.9 0.8 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Sulfotransfer_2 PF03567.14 CBY18852.1 - 2.4e-05 24.4 0.1 4.7e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY18852.1 - 0.027 14.0 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Connexin PF00029.19 CBY18853.1 - 3.9e-48 164.2 4.3 5e-48 163.9 4.3 1.1 1 0 0 1 1 1 1 Connexin wnt PF00110.19 CBY18854.1 - 1.6e-87 294.0 30.9 1.8e-87 293.8 30.9 1.0 1 0 0 1 1 1 1 wnt family Pkinase PF00069.25 CBY18855.1 - 7.9e-45 153.3 0.0 9.9e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY18855.1 - 2e-21 76.5 0.0 2.5e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY18855.1 - 1.3e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY18855.1 - 1.9e-05 23.8 0.5 2.9e-05 23.2 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY18855.1 - 4e-05 23.7 0.2 0.00073 19.5 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBY18855.1 - 5.9e-05 22.7 1.7 9.2e-05 22.1 1.7 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CBY18855.1 - 9.8e-05 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY18855.1 - 0.0015 17.9 1.0 0.0026 17.2 1.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5492 PF17596.2 CBY18855.1 - 0.039 14.3 1.3 0.11 12.9 1.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5492) Kinase-PolyVal PF18762.1 CBY18855.1 - 0.12 12.3 0.4 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins FTA2 PF13095.6 CBY18855.1 - 0.15 11.6 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SPATA48 PF15073.6 CBY18857.1 - 1.5e-06 28.5 0.9 3.5e-06 27.4 0.9 1.6 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 EF-hand_8 PF13833.6 CBY18859.1 - 0.15 12.0 0.0 9.9 6.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair AA_permease_2 PF13520.6 CBY18860.1 - 2e-44 152.1 21.2 2e-44 152.1 21.2 1.9 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 CBY18860.1 - 2.5e-31 108.8 26.3 2.5e-31 108.8 26.3 1.8 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 CBY18860.1 - 1.3e-20 73.2 9.0 1.3e-20 73.2 9.0 3.1 3 0 0 3 3 3 1 C-terminus of AA_permease Vesiculo_matrix PF06326.12 CBY18860.1 - 0.032 14.0 0.1 0.049 13.4 0.1 1.2 1 0 0 1 1 1 0 Vesiculovirus matrix protein DUF4708 PF15813.5 CBY18861.1 - 0.029 13.6 0.1 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4708) EF-hand_1 PF00036.32 CBY18862.1 - 6.6e-15 53.5 3.3 3.9e-07 29.1 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY18862.1 - 9.4e-15 53.2 2.3 6.6e-06 25.6 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY18862.1 - 7.4e-13 47.4 2.1 3.2e-06 26.4 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY18862.1 - 1.3e-07 32.0 1.6 0.0074 16.7 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY18862.1 - 0.0004 20.2 3.5 0.25 11.2 0.1 3.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CBY18862.1 - 0.12 12.7 0.2 32 4.9 0.0 3.0 3 1 0 3 3 3 0 EF-hand domain Excalibur PF05901.11 CBY18862.1 - 0.17 12.6 1.7 5.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Excalibur calcium-binding domain EMC3_TMCO1 PF01956.16 CBY18862.1 - 0.4 10.4 1.7 1.7 8.3 0.1 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Caleosin PF05042.13 CBY18862.1 - 0.41 10.6 2.5 12 5.8 0.1 2.9 2 1 0 3 3 3 0 Caleosin related protein NPC1_N PF16414.5 CBY18863.1 - 2.1e-74 250.2 12.0 3.6e-74 249.4 12.0 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 CBY18863.1 - 7.1e-71 239.4 33.0 9.1e-46 156.4 8.3 2.5 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CBY18863.1 - 8.2e-55 184.8 7.5 8.2e-55 184.8 7.5 2.8 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CBY18863.1 - 2.6e-05 23.3 4.2 2.6e-05 23.3 4.2 2.8 2 0 0 2 2 2 1 MMPL family Zip PF02535.22 CBY18864.1 - 8.3e-43 146.9 11.0 1.1e-29 103.7 4.5 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter UPF0370 PF13980.6 CBY18864.1 - 0.1 12.7 0.4 0.2 11.7 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) UMPH-1 PF05822.12 CBY18867.1 - 1.4e-63 214.7 0.3 1.7e-63 214.4 0.3 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Erp_C PF06780.11 CBY18867.1 - 0.061 13.3 0.2 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Erp protein C-terminus G-alpha PF00503.20 CBY18868.1 - 0.055 12.6 2.9 2.3 7.3 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Kelch_1 PF01344.25 CBY18870.1 - 3.3e-11 42.6 0.2 0.015 14.9 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CBY18870.1 - 4.5e-11 42.3 5.3 0.013 15.4 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CBY18870.1 - 2.5e-06 27.6 1.5 0.0067 16.7 0.0 3.7 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY18870.1 - 3.1e-06 27.0 0.1 0.052 13.6 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 CBY18870.1 - 5.9e-06 26.2 2.9 0.21 11.6 0.0 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain PRiA4_ORF3 PF07929.11 CBY18871.1 - 0.0023 17.7 1.1 0.0034 17.1 1.1 1.3 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Spt20 PF12090.8 CBY18871.1 - 0.062 12.9 1.0 0.065 12.8 0.4 1.4 1 1 0 1 1 1 0 Spt20 family KMP11 PF03037.16 CBY18871.1 - 0.069 13.9 0.8 0.069 13.9 0.8 1.5 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 NPR3 PF03666.13 CBY18871.1 - 0.14 11.0 1.3 0.17 10.7 1.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.10 CBY18871.1 - 1.4 8.2 10.4 1.4 8.2 10.4 1.1 1 0 0 1 1 1 0 BUD22 Aldo_ket_red PF00248.21 CBY18872.1 - 4.3e-50 170.6 0.0 5.3e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Varsurf_PPLC PF03490.13 CBY18873.1 - 0.0057 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C VWA PF00092.28 CBY18875.1 - 2.7e-29 102.7 0.1 4.1e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY18875.1 - 2.3e-11 44.3 0.0 5.3e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY18875.1 - 0.031 14.2 0.0 2 8.4 0.0 2.7 2 0 0 2 2 2 0 von Willebrand factor type A domain AAA_23 PF13476.6 CBY18875.1 - 0.069 13.6 6.1 0.1 13.1 6.1 1.3 1 0 0 1 1 1 0 AAA domain Nsp1_C PF05064.13 CBY18875.1 - 0.15 11.9 3.8 0.31 10.9 3.8 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region G-gamma PF00631.22 CBY18876.1 - 2.9e-13 49.6 0.0 3.1e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 GGL domain DUF5103 PF17116.5 CBY18876.1 - 0.021 14.1 0.2 0.021 14.1 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) CarboxypepD_reg PF13620.6 CBY18878.1 - 6.9e-38 128.8 0.2 3e-07 30.6 0.2 8.6 9 0 0 9 9 9 6 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 CBY18878.1 - 2.2e-24 85.8 1.4 2.4e-05 24.5 0.1 7.4 7 1 1 8 8 8 4 SdrD B-like domain DUF2012 PF09430.10 CBY18878.1 - 2.9e-18 66.2 6.3 0.0013 18.9 0.0 8.7 5 3 2 8 8 8 4 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 CBY18878.1 - 2.2e-13 50.0 9.5 0.0028 17.6 0.0 7.0 8 0 0 8 8 8 4 CarboxypepD_reg-like domain SpaA PF17802.1 CBY18878.1 - 3.5e-11 43.3 0.9 0.011 16.0 0.0 6.3 5 1 1 6 6 6 2 Prealbumin-like fold domain TTR-52 PF01060.23 CBY18878.1 - 4.3e-05 24.1 0.0 11 6.8 0.0 5.3 5 0 0 5 5 5 1 Transthyretin-like family DUF1416 PF07210.12 CBY18878.1 - 8.3e-05 22.4 0.9 0.0013 18.6 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1416) DUF2846 PF11008.8 CBY18878.1 - 0.00015 21.7 1.6 0.22 11.6 0.0 5.5 7 0 0 7 7 7 1 Protein of unknown function (DUF2846) Big_1 PF02369.16 CBY18878.1 - 0.00054 19.9 10.0 0.52 10.4 0.5 6.9 8 0 0 8 8 8 1 Bacterial Ig-like domain (group 1) Y_Y_Y PF07495.13 CBY18878.1 - 0.0013 18.7 0.1 0.5 10.4 0.0 4.3 3 0 0 3 3 3 1 Y_Y_Y domain EMP24_GP25L PF01105.24 CBY18878.1 - 0.0081 16.1 1.2 0.71 9.8 0.1 3.8 3 1 1 4 4 4 1 emp24/gp25L/p24 family/GOLD MetallophosN PF16371.5 CBY18878.1 - 0.0086 16.3 1.6 0.88 9.9 0.1 3.9 3 0 0 3 3 3 1 N terminal of Calcineurin-like phosphoesterase MORN PF02493.20 CBY18879.1 - 7e-07 28.8 17.4 0.0015 18.3 1.0 5.0 5 1 0 5 5 5 3 MORN repeat Mak10 PF04112.13 CBY18880.1 - 1.9e-19 69.8 0.0 2.5e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mak10 PF04112.13 CBY18881.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Sugar_tr PF00083.24 CBY18882.1 - 5e-31 108.1 19.3 8e-31 107.4 19.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY18882.1 - 6.7e-19 68.0 51.6 1.9e-15 56.7 31.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Lectin_C PF00059.21 CBY18883.1 - 3.2e-06 27.8 0.5 4.5e-06 27.4 0.5 1.3 1 0 0 1 1 1 1 Lectin C-type domain Sulfotransfer_1 PF00685.27 CBY18884.1 - 5.8e-09 35.8 0.0 2.2e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY18884.1 - 6.1e-06 26.8 0.1 3.2e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family Somatomedin_B PF01033.17 CBY18884.1 - 1e-05 25.8 13.6 1e-05 25.8 13.6 2.3 2 0 0 2 2 2 1 Somatomedin B domain DS PF01916.17 CBY18885.1 - 0.024 13.9 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase EnY2 PF10163.9 CBY18885.1 - 0.08 13.3 0.9 0.14 12.5 0.9 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 Forkhead PF00250.18 CBY18886.1 - 2.3e-37 127.1 0.3 6.1e-37 125.8 0.3 1.8 1 0 0 1 1 1 1 Forkhead domain Apt1 PF10351.9 CBY18887.1 - 0.0077 15.1 0.2 0.0086 15.0 0.2 1.2 1 1 0 1 1 1 1 Golgi-body localisation protein domain zf-MYND PF01753.18 CBY18889.1 - 9.2e-11 41.7 14.1 9.2e-11 41.7 14.1 2.8 3 0 0 3 3 3 1 MYND finger zf-HIT PF04438.16 CBY18889.1 - 0.00092 19.0 10.9 0.00092 19.0 10.9 2.2 2 0 0 2 2 2 1 HIT zinc finger RRM_1 PF00076.22 CBY18890.1 - 1.3e-32 111.4 0.3 6.4e-15 54.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY18890.1 - 2.2e-05 24.1 0.1 0.042 13.4 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 CBY18890.1 - 0.0098 15.7 0.0 0.37 10.6 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1866) RBM39linker PF15519.6 CBY18890.1 - 0.027 15.6 0.3 0.14 13.3 0.3 2.2 1 1 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Sod_Cu PF00080.20 CBY18890.1 - 0.032 14.4 0.2 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Copper/zinc superoxide dismutase (SODC) PKD_channel PF08016.12 CBY18891.1 - 1.1e-76 258.2 5.8 1.5e-76 257.8 5.8 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CBY18891.1 - 5.3e-17 61.9 27.4 5.3e-17 61.9 27.4 1.6 2 0 0 2 2 2 1 Ion transport protein EF-hand_6 PF13405.6 CBY18891.1 - 0.29 11.2 1.9 1.1 9.3 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 CBY18891.1 - 0.56 10.7 3.6 0.99 9.9 0.2 2.5 2 1 1 3 3 3 0 EF-hand domain pair ADH_zinc_N_2 PF13602.6 CBY18892.1 - 3.9e-08 34.4 0.0 1.2e-07 32.9 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 CBY18892.1 - 0.0038 17.6 0.0 0.0076 16.7 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 CBY18892.1 - 0.014 14.9 0.1 0.028 13.9 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 CBY18892.1 - 0.11 11.8 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CbiD PF01888.17 CBY18892.1 - 0.11 11.8 2.0 1 8.6 2.4 2.2 1 1 1 2 2 2 0 CbiD NAD_binding_7 PF13241.6 CBY18892.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 CBY18892.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TAF PF02969.17 CBY18893.1 - 8.4e-05 22.7 0.1 0.00016 21.8 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) YIF1 PF03878.15 CBY18894.1 - 2.3e-75 253.2 0.8 3.1e-75 252.8 0.8 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 CBY18894.1 - 1e-10 41.6 1.1 1.6e-10 40.9 1.1 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2269 PF10027.9 CBY18894.1 - 0.035 14.2 1.2 0.073 13.1 0.1 2.0 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF1282 PF06930.12 CBY18894.1 - 0.045 13.5 4.4 0.078 12.8 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF4233 PF14017.6 CBY18894.1 - 1.2 9.5 7.8 2.7 8.4 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Scs3p PF10261.9 CBY18895.1 - 3.5e-17 62.7 15.6 4e-13 49.4 4.4 2.5 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM ArfGap PF01412.18 CBY18896.1 - 3.9e-31 107.5 0.1 1e-30 106.2 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NOG1_N PF17835.1 CBY18896.1 - 0.0021 18.0 0.9 0.0056 16.7 0.3 2.0 1 1 1 2 2 2 1 NOG1 N-terminal helical domain Prok-TraM PF09228.10 CBY18896.1 - 0.048 14.0 0.7 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM HTH_OrfB_IS605 PF12323.8 CBY18897.1 - 0.097 12.2 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Lectin_leg-like PF03388.13 CBY18899.1 - 4.6e-70 235.5 0.4 6.4e-70 235.1 0.4 1.2 1 0 0 1 1 1 1 Legume-like lectin family DUF1664 PF07889.12 CBY18899.1 - 1.6 8.8 9.9 5.3 7.1 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Histone PF00125.24 CBY18901.1 - 1.4e-21 77.2 0.6 1.7e-21 76.9 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY18901.1 - 5.4e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY18901.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY18901.1 - 0.00041 20.4 0.3 0.00044 20.3 0.3 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY18901.1 - 0.033 14.4 0.7 0.087 13.1 0.7 1.7 1 1 0 1 1 1 0 CENP-W protein Histone_H2A_C PF16211.5 CBY18902.1 - 2e-20 72.2 1.3 4.1e-20 71.2 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY18902.1 - 5.8e-16 59.0 0.0 7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY18902.1 - 3.8e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Linker_histone PF00538.19 CBY18903.1 - 1.4e-29 102.2 1.1 1.4e-29 102.2 1.1 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 CBY18903.1 - 0.0002 21.5 67.8 0.00023 21.3 38.0 2.3 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 CENP-T_C PF15511.6 CBY18904.1 - 3.3e-08 33.6 0.1 4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY18904.1 - 4.7e-05 23.5 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY18904.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY18904.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY18904.1 - 0.00033 21.0 0.2 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY18904.1 - 0.012 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY18904.1 - 0.046 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY18904.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CBY18905.1 - 2.1e-19 70.2 6.2 8e-17 61.8 0.1 2.2 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CBY18905.1 - 0.029 14.9 2.5 0.038 14.6 2.5 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY18905.1 - 0.069 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein BUD22 PF09073.10 CBY18906.1 - 8.7 5.6 9.3 10 5.4 9.3 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 CBY18906.1 - 8.9 5.3 18.4 10 5.1 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kelch_1 PF01344.25 CBY18907.1 - 1.4e-15 56.5 1.8 6.2e-07 28.9 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CBY18907.1 - 5.8e-14 51.8 0.8 0.0018 18.2 0.0 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY18907.1 - 5.9e-13 48.6 4.1 0.00016 21.9 0.0 5.3 3 1 3 6 6 6 2 Kelch motif BACK PF07707.15 CBY18907.1 - 9.3e-12 45.0 0.5 2e-11 43.9 0.5 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CBY18907.1 - 2.2e-09 36.9 1.0 0.0018 18.2 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY18907.1 - 3.5e-06 26.9 1.5 1.8 8.6 0.0 4.4 5 0 0 5 5 5 3 Kelch motif BTB PF00651.31 CBY18907.1 - 0.0003 21.0 0.0 0.00066 19.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PDE4_UCR PF18100.1 CBY18907.1 - 0.049 14.3 0.2 0.1 13.2 0.2 1.5 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) Smr PF01713.21 CBY18908.1 - 1.3e-09 38.3 0.1 3.3e-09 37.0 0.1 1.7 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.10 CBY18908.1 - 2.5e-06 27.7 10.1 5.6e-06 26.6 10.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 CBY18908.1 - 0.001 18.7 0.2 0.27 11.0 0.0 3.1 3 0 0 3 3 3 2 CUE domain AAA_33 PF13671.6 CBY18909.1 - 7.8e-11 42.3 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CUE PF02845.16 CBY18909.1 - 3.5e-06 26.6 0.1 0.0024 17.5 0.0 2.4 2 0 0 2 2 2 2 CUE domain KTI12 PF08433.10 CBY18909.1 - 1.9e-05 24.2 0.0 4.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF1296 PF06972.11 CBY18909.1 - 0.0084 16.2 0.1 0.22 11.7 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1296) SRP54 PF00448.22 CBY18909.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 CBY18909.1 - 0.018 15.4 0.5 0.05 14.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CBY18909.1 - 0.024 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_32 PF13654.6 CBY18909.1 - 0.034 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY18909.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY18909.1 - 0.048 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CBY18909.1 - 0.059 13.9 1.1 0.19 12.2 0.0 2.5 3 1 0 3 3 3 0 ABC transporter ATPase_2 PF01637.18 CBY18909.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CBY18909.1 - 0.063 12.5 0.1 0.27 10.5 0.1 2.1 2 1 0 2 2 2 0 Zeta toxin UIM PF02809.20 CBY18909.1 - 0.075 13.0 0.3 0.22 11.5 0.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Complex1_LYR_2 PF13233.6 CBY18910.1 - 2.2e-11 44.3 0.1 2.8e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CBY18910.1 - 0.00022 21.2 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ACBP PF00887.19 CBY18910.1 - 0.057 13.6 0.3 0.95 9.7 0.2 2.1 1 1 1 2 2 2 0 Acyl CoA binding protein MFS_1 PF07690.16 CBY18911.1 - 8.5e-14 51.2 19.1 8.5e-14 51.2 19.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.20 CBY18912.1 - 4.1e-47 160.7 24.5 4.7e-47 160.5 24.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Endomucin PF07010.12 CBY18912.1 - 0.26 11.2 0.3 0.41 10.6 0.3 1.2 1 0 0 1 1 1 0 Endomucin HA2 PF04408.23 CBY18913.1 - 1.6e-16 60.5 0.0 4.2e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY18913.1 - 1.4e-15 57.6 0.1 8.4e-15 55.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain dsrm PF00035.26 CBY18913.1 - 1.9e-09 38.1 3.8 7.7e-06 26.5 0.1 3.7 2 1 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 CBY18913.1 - 2.3e-09 37.2 0.0 4.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CBY18913.1 - 2.6e-06 27.7 0.1 4.9e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Dicer_dimer PF03368.14 CBY18913.1 - 0.00011 22.3 0.1 0.14 12.3 0.0 3.0 2 1 0 2 2 2 2 Dicer dimerisation domain ResIII PF04851.15 CBY18913.1 - 0.0033 17.4 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase PF06745.13 CBY18913.1 - 0.005 16.2 0.1 0.091 12.1 0.0 2.3 2 0 0 2 2 2 1 KaiC T2SSE PF00437.20 CBY18913.1 - 0.0077 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CBY18913.1 - 0.011 16.1 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY18913.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.15 CBY18913.1 - 0.17 9.9 0.0 0.26 9.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein His_Phos_1 PF00300.22 CBY18914.1 - 4.6e-20 72.1 0.8 5.6e-19 68.6 0.8 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF383 PF04063.14 CBY18915.1 - 4.3e-50 170.0 0.8 6.1e-49 166.3 0.1 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CBY18915.1 - 6.7e-10 38.7 0.6 5.2e-09 35.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Importin_rep_3 PF18806.1 CBY18915.1 - 0.13 12.3 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Importin 13 repeat FAM76 PF16046.5 CBY18916.1 - 1.8e-78 264.0 37.6 1.8e-78 264.0 37.6 2.5 2 1 0 2 2 2 1 FAM76 protein RIIa PF02197.17 CBY18917.1 - 0.00033 20.2 0.0 0.00074 19.1 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Homeodomain PF00046.29 CBY18919.1 - 1.9e-18 66.1 5.4 3e-18 65.4 5.4 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY18919.1 - 0.011 15.6 0.7 0.031 14.2 0.2 1.9 2 0 0 2 2 2 0 Homeobox KN domain GHMP_kinases_N PF00288.26 CBY18920.1 - 8.1e-07 29.2 0.0 2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBY18920.1 - 1.1e-05 25.7 0.1 2.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal NTP_transferase PF00483.23 CBY18920.1 - 0.00045 19.9 0.0 0.0011 18.6 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Peptidase_C15 PF01470.17 CBY18921.1 - 0.0091 16.2 0.1 0.028 14.6 0.1 1.8 1 1 0 1 1 1 1 Pyroglutamyl peptidase GP3 PF03076.14 CBY18921.1 - 0.052 13.6 0.2 0.065 13.3 0.2 1.1 1 0 0 1 1 1 0 Equine arteritis virus GP3 cNMP_binding PF00027.29 CBY18922.1 - 1.5e-36 124.4 0.2 2.8e-18 65.8 0.0 2.5 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain fragilysinNterm PF16376.5 CBY18922.1 - 0.021 14.6 1.0 2.1 8.1 0.2 2.4 1 1 1 2 2 2 0 N-terminal domain of fragilysin KIND PF16474.5 CBY18922.1 - 0.053 13.4 2.3 0.11 12.4 2.3 1.5 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Phage_integrase PF00589.22 CBY18927.1 - 4.7e-09 36.3 0.0 8.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family GCM PF03615.15 CBY18927.1 - 0.042 13.7 0.1 0.076 12.9 0.1 1.4 1 0 0 1 1 1 0 GCM motif protein ACAS_N PF16177.5 CBY18927.1 - 0.15 12.0 1.8 19 5.3 1.1 2.8 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus RIIa PF02197.17 CBY18928.1 - 5.6e-11 41.9 0.0 7.3e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Thg1 PF04446.12 CBY18929.1 - 3.3e-42 143.4 0.0 6.8e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 CBY18929.1 - 9e-41 138.9 3.3 1.5e-40 138.2 1.8 1.9 2 0 0 2 2 2 1 Thg1 C terminal domain MCU PF04678.13 CBY18930.1 - 3e-51 174.0 0.5 4.5e-51 173.4 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Hpt PF01627.23 CBY18930.1 - 0.054 13.8 1.4 0.094 13.0 0.1 2.1 2 0 0 2 2 2 0 Hpt domain Mod_r PF07200.13 CBY18930.1 - 0.66 10.1 6.8 0.15 12.2 2.4 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Phospholip_A2_1 PF00068.19 CBY18931.1 - 2.5e-18 66.6 8.0 2.5e-18 66.6 8.0 2.3 3 0 0 3 3 3 1 Phospholipase A2 LPD37 PF18853.1 CBY18932.1 - 0.0076 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Large polyvalent protein associated domain 37 DUF4230 PF14014.6 CBY18932.1 - 0.16 12.2 1.3 0.23 11.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) SET PF00856.28 CBY18934.1 - 5.3e-10 39.9 0.0 2.4e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 SET domain ASC PF00858.24 CBY18936.1 - 5.9e-93 312.2 2.7 9e-93 311.6 2.7 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel bZIP_1 PF00170.21 CBY18937.1 - 0.00021 21.4 16.8 0.00036 20.6 16.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY18937.1 - 0.0026 17.8 17.5 0.0092 16.0 17.5 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY18937.1 - 0.0076 16.7 13.4 0.0085 16.6 12.0 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor BUD22 PF09073.10 CBY18937.1 - 0.012 15.0 6.5 0.016 14.6 6.5 1.1 1 0 0 1 1 1 0 BUD22 PP2C_C PF07830.13 CBY18937.1 - 0.015 15.7 1.0 0.075 13.5 0.2 2.2 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain V_ATPase_I PF01496.19 CBY18937.1 - 0.023 12.6 4.7 0.03 12.3 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cortex-I_coil PF09304.10 CBY18937.1 - 0.028 14.6 7.7 0.043 14.0 7.7 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil SHE3 PF17078.5 CBY18937.1 - 0.029 14.1 6.9 0.043 13.5 6.9 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 FlaC_arch PF05377.11 CBY18937.1 - 0.032 14.6 3.4 0.057 13.8 2.9 1.7 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Phage_lysozyme2 PF18013.1 CBY18937.1 - 0.062 13.3 1.6 0.094 12.7 1.6 1.2 1 0 0 1 1 1 0 Phage tail lysozyme PWWP PF00855.17 CBY18938.1 - 6e-13 49.0 2.5 9.5e-13 48.4 0.7 2.1 1 1 1 2 2 2 1 PWWP domain FF PF01846.19 CBY18939.1 - 4.1e-37 126.1 48.1 1.2e-11 44.6 5.3 6.5 6 0 0 6 6 6 5 FF domain WW PF00397.26 CBY18939.1 - 9.2e-14 51.2 1.6 2.2e-06 27.6 0.3 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 CBY18939.1 - 4.2e-06 27.3 14.6 0.00032 21.3 1.7 4.4 2 1 1 3 3 3 2 p190-A and -B Rho GAPs FF domain XRN_N PF03159.18 CBY18940.1 - 2.6e-96 321.7 1.8 8.5e-96 320.0 0.0 2.3 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBY18940.1 - 4.8e-83 279.6 8.9 4.8e-83 279.6 8.9 2.8 2 1 0 2 2 2 1 Xrn1 helical domain SH3_12 PF18129.1 CBY18940.1 - 4e-20 71.7 0.0 8e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 CBY18940.1 - 6.1e-20 71.8 0.0 1.6e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 CBY18940.1 - 0.00037 20.6 0.5 0.00083 19.5 0.0 2.0 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain DUF2730 PF10805.8 CBY18941.1 - 1.7e-05 24.8 0.6 1.7e-05 24.8 0.6 4.1 2 2 2 4 4 4 1 Protein of unknown function (DUF2730) TMPIT PF07851.13 CBY18941.1 - 0.007 15.6 28.6 0.025 13.8 1.6 3.3 2 1 1 3 3 3 2 TMPIT-like protein EcsC PF12787.7 CBY18941.1 - 0.059 13.0 0.5 0.059 13.0 0.5 2.9 2 1 0 2 2 2 0 EcsC protein family BLOC1_2 PF10046.9 CBY18941.1 - 0.096 13.0 34.0 0.54 10.6 3.0 4.9 3 3 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MSV199 PF10553.9 CBY18941.1 - 1.5 9.1 9.9 0.055 13.7 2.0 2.6 2 1 1 3 3 3 0 MSV199 domain GIT_CC PF16559.5 CBY18941.1 - 3 7.8 18.9 1.2 9.0 0.9 4.9 3 2 2 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2721 PF11026.8 CBY18941.1 - 3.1 7.7 4.9 2.8 7.8 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1664 PF07889.12 CBY18941.1 - 3.4 7.7 29.8 0.23 11.5 1.6 4.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) PSI_PsaF PF02507.15 CBY18941.1 - 4.8 7.0 6.4 4 7.2 0.6 3.0 2 1 1 3 3 3 0 Photosystem I reaction centre subunit III DUF812 PF05667.11 CBY18941.1 - 4.9 5.9 42.5 5.5 5.7 37.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) M PF02370.16 CBY18941.1 - 5 8.0 14.0 88 4.2 0.2 5.3 3 1 0 3 3 3 0 M protein repeat Spc7 PF08317.11 CBY18941.1 - 7.8 5.3 41.9 2 7.2 15.3 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein ECM11 PF15463.6 CBY18941.1 - 7.8 7.1 19.5 0.099 13.2 5.9 3.4 2 2 1 3 3 3 0 Extracellular mutant protein 11 RNase_PH PF01138.21 CBY18942.1 - 3e-19 69.8 0.0 6.1e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBY18942.1 - 1e-07 31.9 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Duffy_binding PF05424.11 CBY18942.1 - 0.035 14.1 0.3 0.062 13.3 0.3 1.4 1 0 0 1 1 1 0 Duffy binding domain PEN-2 PF10251.9 CBY18943.1 - 5e-38 129.4 3.5 5.6e-38 129.2 3.5 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase COX14 PF14880.6 CBY18943.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Pro_isomerase PF00160.21 CBY18944.1 - 7.1e-47 159.6 0.3 8.5e-47 159.4 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 CBY18945.1 - 1.3e-41 142.5 0.6 1.7e-41 142.1 0.6 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF739 PF05339.11 CBY18945.1 - 0.034 14.3 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF739) IBR PF01485.21 CBY18946.1 - 8.8e-10 38.7 27.3 2.4e-07 30.9 4.0 5.2 4 2 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_14 PF17978.1 CBY18946.1 - 3.5e-06 27.3 1.9 3.5e-06 27.3 1.9 2.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF3330 PF11809.8 CBY18946.1 - 0.0061 16.6 1.5 0.0061 16.6 1.5 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3330) Glyco_transf_8 PF01501.20 CBY18947.1 - 0.017 14.7 0.5 1.5 8.3 0.0 2.3 2 1 0 2 2 2 0 Glycosyl transferase family 8 Pkinase PF00069.25 CBY18948.1 - 9.8e-33 113.6 0.0 1.5e-32 113.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CBY18948.1 - 5.3e-08 32.5 0.0 8.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CBY18948.1 - 6.7e-07 28.8 0.0 8.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY18948.1 - 7.7e-05 22.7 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY18948.1 - 0.002 17.8 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CBY18948.1 - 0.0022 17.3 0.0 0.0062 15.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBY18948.1 - 0.0063 15.3 0.0 0.017 13.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY18948.1 - 0.02 13.8 0.1 0.64 8.9 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 CBY18948.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 1 1 2 2 2 0 RIO1 family Nuc_recep-AF1 PF11825.8 CBY18949.1 - 1.4 9.0 11.2 0.39 10.8 7.5 1.9 2 0 0 2 2 2 0 Nuclear/hormone receptor activator site AF-1 Na_H_Exchanger PF00999.21 CBY18951.1 - 5.6e-17 61.6 25.3 5.6e-17 61.6 25.3 2.2 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family Ion_trans PF00520.31 CBY18951.1 - 5.5e-13 48.7 6.3 5.5e-13 48.7 6.3 4.3 4 1 0 4 4 4 2 Ion transport protein cNMP_binding PF00027.29 CBY18951.1 - 2.2e-09 37.3 0.0 6.2e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain fn3 PF00041.21 CBY18952.1 - 0 1975.2 85.9 5.6e-14 52.3 0.1 54.3 52 2 1 53 53 53 51 Fibronectin type III domain I-set PF07679.16 CBY18952.1 - 0 1337.5 39.5 9.8e-19 67.2 0.0 39.9 39 1 0 39 39 38 33 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY18952.1 - 8.3e-252 814.6 23.2 1.3e-10 41.8 0.0 37.0 36 0 0 36 36 36 33 Immunoglobulin domain Ig_2 PF13895.6 CBY18952.1 - 1.1e-96 317.2 19.4 8.7e-09 35.6 0.0 30.1 32 0 0 32 32 31 15 Immunoglobulin domain ig PF00047.25 CBY18952.1 - 1.6e-87 287.8 26.3 1.4e-07 31.6 0.0 28.7 31 0 0 31 31 31 14 Immunoglobulin domain Pkinase PF00069.25 CBY18952.1 - 5.3e-57 193.2 0.0 8.8e-57 192.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pur_ac_phosph_N PF16656.5 CBY18952.1 - 2.5e-43 146.6 90.9 0.32 11.6 0.0 42.8 45 4 0 45 45 43 7 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 CBY18952.1 - 2.8e-31 107.5 0.0 0.12 12.6 0.0 25.5 32 0 0 32 32 26 2 Fibronectin type III domain V-set PF07686.17 CBY18952.1 - 2.5e-30 104.9 48.7 0.082 13.1 0.1 29.0 32 4 1 33 33 29 9 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 CBY18952.1 - 6.3e-26 91.2 0.0 1.1e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.12 CBY18952.1 - 6.3e-25 87.1 31.1 0.67 10.1 0.0 24.5 29 0 0 29 29 28 4 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 CBY18952.1 - 1.1e-19 70.6 9.8 0.66 10.2 0.0 19.1 21 0 0 21 21 19 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 CBY18952.1 - 8.9e-07 28.9 2.7 4.7 7.4 0.0 8.8 9 0 0 9 9 7 1 Izumo-like Immunoglobulin domain DUF756 PF05506.12 CBY18952.1 - 0.00019 22.3 19.6 78 4.3 0.0 16.7 20 3 0 20 20 11 0 Domain of unknown function (DUF756) Interfer-bind PF09294.10 CBY18952.1 - 0.00082 19.7 7.4 13 6.1 0.2 9.3 7 0 0 7 7 7 0 Interferon-alpha/beta receptor, fibronectin type III Methyltransf_9 PF08003.11 CBY18952.1 - 0.0019 17.2 0.1 1.6 7.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) Kinase-like PF14531.6 CBY18952.1 - 0.0036 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Big_7 PF17957.1 CBY18952.1 - 0.036 14.8 14.2 0.34 11.7 0.1 7.2 7 0 0 7 7 4 0 Bacterial Ig domain TraK PF06586.11 CBY18952.1 - 0.046 13.4 0.3 68 3.0 0.0 4.7 5 0 0 5 5 5 0 TraK protein bMG3 PF11974.8 CBY18952.1 - 0.054 13.5 0.1 49 4.0 0.0 4.1 4 0 0 4 4 2 0 Bacterial alpha-2-macroglobulin MG3 domain Cu-oxidase PF00394.22 CBY18952.1 - 0.11 12.6 0.6 5.9 7.0 0.0 4.2 4 0 0 4 4 3 0 Multicopper oxidase 2OG-FeII_Oxy_2 PF13532.6 CBY18952.1 - 0.16 12.1 0.0 0.5 10.5 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1655 PF07868.11 CBY18952.1 - 0.25 11.4 1.1 1.6e+02 2.4 0.0 3.9 4 0 0 4 4 3 0 Protein of unknown function (DUF1655) Tropomyosin PF00261.20 CBY18953.1 - 1.6e-27 96.4 53.1 1.8e-27 96.2 53.1 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 CBY18953.1 - 1.4e-11 44.8 51.8 2.2e-06 27.9 20.1 3.3 1 1 2 3 3 3 3 Tropomyosin like DHR10 PF18595.1 CBY18953.1 - 3.1e-05 24.0 50.7 0.0038 17.3 11.6 3.7 1 1 2 3 3 3 2 Designed helical repeat protein 10 domain GAS PF13851.6 CBY18953.1 - 5.9e-05 22.5 40.7 0.04 13.3 10.7 3.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 CBY18953.1 - 0.00013 22.1 39.6 0.055 13.7 6.1 4.0 1 1 3 4 4 4 2 TATA element modulatory factor 1 TATA binding ERM PF00769.19 CBY18953.1 - 0.00089 19.1 43.4 0.0014 18.5 43.3 1.4 1 1 0 1 1 1 1 Ezrin/radixin/moesin family Fez1 PF06818.15 CBY18953.1 - 0.00099 19.6 40.0 0.012 16.0 17.4 2.6 1 1 1 2 2 2 1 Fez1 CLZ PF16526.5 CBY18953.1 - 0.001 19.4 34.4 0.023 15.0 7.8 4.1 3 3 1 4 4 4 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-Q PF13094.6 CBY18953.1 - 0.0013 19.0 7.5 0.0013 19.0 7.5 4.0 1 1 2 3 3 2 1 CENP-Q, a CENPA-CAD centromere complex subunit MCC-bdg_PDZ PF10506.9 CBY18953.1 - 0.0021 18.0 17.9 0.013 15.5 1.6 4.3 3 2 1 4 4 4 1 PDZ domain of MCC-2 bdg protein for Usher syndrome PKcGMP_CC PF16808.5 CBY18953.1 - 0.0053 16.6 2.2 0.0053 16.6 2.2 4.8 5 2 1 6 6 4 1 Coiled-coil N-terminus of cGMP-dependent protein kinase CENP-F_leu_zip PF10473.9 CBY18953.1 - 0.0064 16.5 45.8 1 9.4 7.7 3.4 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 CBY18953.1 - 0.01 15.9 4.2 0.01 15.9 4.2 5.7 1 1 6 7 7 7 1 Centrosome localisation domain of PPC89 Prefoldin PF02996.17 CBY18953.1 - 0.033 14.1 30.6 0.21 11.5 3.6 4.6 2 2 0 4 4 4 0 Prefoldin subunit DUF3450 PF11932.8 CBY18953.1 - 0.049 12.9 38.8 0.13 11.6 8.7 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) BRE1 PF08647.11 CBY18953.1 - 0.066 13.3 36.2 0.12 12.4 3.3 4.1 1 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 CBY18953.1 - 0.081 13.5 54.2 0.14 12.6 15.6 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Leu_zip PF15294.6 CBY18953.1 - 0.084 12.4 35.8 0.021 14.4 26.1 2.1 1 1 1 2 2 2 0 Leucine zipper AAA_13 PF13166.6 CBY18953.1 - 0.084 11.5 32.7 0.25 10.0 19.6 2.1 1 1 1 2 2 2 0 AAA domain XhlA PF10779.9 CBY18953.1 - 0.12 12.5 35.0 0.19 11.9 3.2 4.9 3 2 1 5 5 5 0 Haemolysin XhlA PspA_IM30 PF04012.12 CBY18953.1 - 0.18 11.4 37.5 0.43 10.1 8.1 3.0 1 1 2 3 3 3 0 PspA/IM30 family ATG16 PF08614.11 CBY18953.1 - 0.19 11.9 47.2 0.6 10.3 27.6 3.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Nsp1_C PF05064.13 CBY18953.1 - 0.22 11.3 23.2 0.1 12.4 3.1 3.5 2 1 2 4 4 4 0 Nsp1-like C-terminal region T3SSipB PF16535.5 CBY18953.1 - 0.25 11.8 27.7 0.064 13.7 7.2 3.6 1 1 2 3 3 3 0 Type III cell invasion protein SipB TPR_MLP1_2 PF07926.12 CBY18953.1 - 0.31 11.1 48.8 0.055 13.5 20.1 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 CBY18953.1 - 0.33 10.6 42.7 1 9.0 14.6 3.6 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease BST2 PF16716.5 CBY18953.1 - 0.51 11.0 35.4 0.24 12.0 7.9 4.8 1 1 2 4 4 4 0 Bone marrow stromal antigen 2 ADIP PF11559.8 CBY18953.1 - 0.72 9.9 42.1 1.5 8.9 6.7 3.9 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CBY18953.1 - 0.73 8.7 45.7 0.12 11.3 20.2 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein HrpB7 PF09486.10 CBY18953.1 - 0.78 10.1 38.1 2.6 8.4 18.8 2.5 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Striatin PF08232.12 CBY18953.1 - 0.8 10.3 29.7 0.26 11.9 15.9 2.4 1 1 1 2 2 2 0 Striatin family EzrA PF06160.12 CBY18953.1 - 0.85 7.7 37.2 0.0093 14.2 16.8 2.5 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DASH_Hsk3 PF08227.11 CBY18953.1 - 0.91 9.9 8.1 11 6.4 0.1 4.6 5 1 1 6 6 3 0 DASH complex subunit Hsk3 like DUF1664 PF07889.12 CBY18953.1 - 1.3 9.1 23.7 0.87 9.6 2.6 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 CBY18953.1 - 1.4 9.0 21.4 0.44 10.7 0.9 5.4 2 2 4 6 6 6 0 bZIP transcription factor HMMR_N PF15905.5 CBY18953.1 - 1.8 8.0 42.4 1.5 8.2 13.2 2.9 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal TMF_DNA_bd PF12329.8 CBY18953.1 - 1.8 8.6 49.1 0.24 11.4 8.2 4.7 1 1 3 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 CBY18953.1 - 1.9 8.9 45.2 0.83 10.1 13.4 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) HIP1_clath_bdg PF16515.5 CBY18953.1 - 2.1 9.0 41.3 8.6 7.0 8.0 4.1 1 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 THOC7 PF05615.13 CBY18953.1 - 2.4 8.4 40.9 0.14 12.5 11.1 3.3 1 1 2 3 3 3 0 Tho complex subunit 7 DUF4201 PF13870.6 CBY18953.1 - 2.5 7.8 35.1 9.8 5.9 19.5 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) KASH_CCD PF14662.6 CBY18953.1 - 2.8 7.7 39.2 1.1 9.0 26.5 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 CBY18953.1 - 3.9 8.4 39.9 2.8 8.9 10.2 4.1 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain FPP PF05911.11 CBY18953.1 - 4.4 5.4 39.0 0.93 7.6 24.9 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF724 PF05266.14 CBY18953.1 - 4.6 7.0 35.3 3.2 7.5 7.1 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) HOOK PF05622.12 CBY18953.1 - 5 5.1 42.8 5.3 5.1 13.7 2.3 1 1 1 2 2 2 0 HOOK protein OmpH PF03938.14 CBY18953.1 - 5 7.4 37.9 2.5 8.4 7.1 3.3 2 2 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 CBY18953.1 - 5.4 4.4 42.8 2 5.8 15.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CALCOCO1 PF07888.11 CBY18953.1 - 5.5 5.7 42.9 0.44 9.4 26.5 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3037 PF11236.8 CBY18953.1 - 5.7 7.4 13.1 1.5 9.3 1.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) TMPIT PF07851.13 CBY18953.1 - 6.3 5.9 26.4 0.85 8.8 6.9 2.9 1 1 3 4 4 4 0 TMPIT-like protein Fib_alpha PF08702.10 CBY18953.1 - 6.9 6.9 23.7 2.2 8.4 8.3 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ABC_tran PF00005.27 CBY18957.1 - 1.1e-50 171.7 0.2 1.1e-24 87.5 0.4 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CBY18957.1 - 1.3e-43 149.5 50.8 4.9e-23 81.8 27.3 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBY18957.1 - 9.6e-20 71.6 14.9 2.8e-08 33.9 0.0 5.3 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY18957.1 - 2.7e-08 33.5 1.2 0.26 10.7 0.0 4.4 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 CBY18957.1 - 2.1e-06 28.3 2.2 0.035 14.8 0.1 3.2 3 0 0 3 3 2 2 Domain of unknown function (DUF4162) AAA_23 PF13476.6 CBY18957.1 - 1.3e-05 25.8 6.2 0.057 13.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CBY18957.1 - 1.6e-05 24.5 0.4 0.21 11.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBY18957.1 - 0.00015 21.7 0.8 0.021 14.7 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 CBY18957.1 - 0.00019 21.2 0.0 9 6.0 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_30 PF13604.6 CBY18957.1 - 0.00049 19.9 1.6 0.061 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBY18957.1 - 0.001 18.9 1.3 0.11 12.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 CBY18957.1 - 0.0012 18.7 3.8 0.055 13.2 0.0 3.6 5 0 0 5 5 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 CBY18957.1 - 0.0012 18.9 0.6 0.67 10.1 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_27 PF13514.6 CBY18957.1 - 0.0023 17.6 0.1 0.32 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MukB PF04310.12 CBY18957.1 - 0.0036 17.1 1.2 0.23 11.2 0.2 2.5 2 0 0 2 2 2 1 MukB N-terminal AAA_16 PF13191.6 CBY18957.1 - 0.0053 17.2 0.1 2.2 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBY18957.1 - 0.026 14.8 2.9 6.4 7.1 0.3 3.1 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 CBY18957.1 - 0.066 12.8 3.2 3.8 7.1 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 CBY18957.1 - 0.12 12.4 0.7 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CBY18957.1 - 0.12 11.6 0.4 16 4.7 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 CBY18957.1 - 0.14 12.2 0.1 18 5.3 0.0 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 CBY18957.1 - 0.18 12.2 0.4 2.4 8.6 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CBY18957.1 - 0.19 12.1 0.3 9.9 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 CBY18957.1 - 5.9 7.1 5.4 37 4.5 0.7 2.4 2 0 0 2 2 2 0 AAA domain Period_C PF12114.8 CBY18958.1 - 0.012 15.2 0.7 0.012 15.2 0.7 1.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region HeH PF12949.7 CBY18959.1 - 3.4e-06 26.7 0.3 6.8e-06 25.7 0.3 1.6 1 0 0 1 1 1 1 HeH/LEM domain DUF525 PF04379.14 CBY18960.1 - 0.011 15.9 0.2 6.1 7.2 0.0 2.8 3 0 0 3 3 3 0 ApaG domain TSNAXIP1_N PF15739.5 CBY18961.1 - 0.031 14.6 6.0 0.027 14.9 3.9 2.0 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus AlkA_N PF06029.11 CBY18961.1 - 0.12 12.7 0.2 1.8 8.8 0.1 2.2 2 0 0 2 2 2 0 AlkA N-terminal domain PikAIV_N PF18605.1 CBY18961.1 - 1.3 8.7 3.9 0.76 9.4 0.9 2.2 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Kelch_1 PF01344.25 CBY18962.1 - 3.6e-11 42.4 6.7 0.00084 18.9 0.0 6.0 7 1 0 7 7 7 3 Kelch motif Kelch_4 PF13418.6 CBY18962.1 - 3.9e-11 42.8 1.9 0.56 10.3 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY18962.1 - 4.3e-09 36.4 0.0 0.13 12.6 0.1 5.8 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY18962.1 - 1.1e-06 28.4 2.1 0.86 9.7 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 CBY18962.1 - 3.3e-06 27.2 6.2 0.15 12.4 0.0 5.9 4 2 2 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBY18962.1 - 1.2e-05 25.1 0.2 0.25 11.4 0.0 3.9 3 0 0 3 3 3 2 Kelch motif PKD_channel PF08016.12 CBY18963.1 - 7.4e-136 453.2 7.7 1.1e-135 452.7 7.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CBY18963.1 - 6e-24 84.6 22.0 6e-24 84.6 22.0 1.5 2 0 0 2 2 2 1 Ion transport protein Fer4_24 PF18109.1 CBY18963.1 - 1.6e-06 28.3 0.0 3.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_1 PF00036.32 CBY18963.1 - 0.00082 18.8 1.5 0.036 13.6 0.3 3.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY18963.1 - 0.035 14.1 3.0 0.25 11.4 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain Abhydrolase_9_N PF15420.6 CBY18963.1 - 0.15 12.0 0.0 0.77 9.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus wnt PF00110.19 CBY18964.1 - 4.8e-33 115.1 21.3 7.2e-32 111.2 21.3 2.0 1 1 0 1 1 1 1 wnt family PTR2 PF00854.21 CBY18965.1 - 4.4e-93 312.2 18.3 5.6e-78 262.5 12.7 2.2 2 0 0 2 2 2 2 POT family Oxidored_q2 PF00420.24 CBY18965.1 - 0.3 10.8 0.1 0.3 10.8 0.1 3.0 4 0 0 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Calx-beta PF03160.14 CBY18966.1 - 6.9e-57 189.8 4.8 1.2e-28 99.2 0.2 2.7 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 CBY18966.1 - 1.9e-49 167.5 31.6 4.6e-26 91.6 11.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 CBY18966.1 - 2e-23 83.2 1.7 9.5e-22 77.8 1.7 2.6 1 1 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain PT-VENN PF04829.13 CBY18966.1 - 1.3 9.1 3.9 4.5 7.4 3.9 1.9 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif COesterase PF00135.28 CBY18967.1 - 5.3e-11 42.1 0.0 7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF2653 PF10850.8 CBY18967.1 - 0.11 12.7 0.0 9 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2653) COesterase PF00135.28 CBY18968.1 - 1.6e-58 198.9 0.0 2e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY18968.1 - 9e-11 42.0 0.2 9.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY18968.1 - 0.005 16.3 0.2 0.0088 15.5 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CBY18968.1 - 0.012 14.8 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 CBY18968.1 - 0.018 13.9 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Esterase PF00756.20 CBY18968.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Lectin_C PF00059.21 CBY18969.1 - 7.9e-15 55.5 16.5 2.1e-07 31.6 0.4 3.9 4 0 0 4 4 4 3 Lectin C-type domain DUF2704 PF10866.8 CBY18969.1 - 0.033 14.1 0.2 0.073 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) DUF5609 PF18429.1 CBY18969.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5609) Mucin PF01456.17 CBY18969.1 - 0.24 11.4 19.5 0.45 10.5 19.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Cys_Knot_tox PF17486.2 CBY18969.1 - 2 8.7 7.6 7.6 6.8 0.4 3.2 2 1 1 3 3 3 0 Cystine knot toxins DUF3439 PF11921.8 CBY18969.1 - 2.2 8.3 10.1 5.2 7.0 10.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Homeobox_KN PF05920.11 CBY18970.1 - 9.7e-20 70.2 1.4 1.9e-19 69.2 1.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY18970.1 - 4.6e-09 36.0 0.8 8e-09 35.2 0.8 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CBY18970.1 - 0.034 13.6 0.0 0.094 12.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez 4PPT_N PF17837.1 CBY18970.1 - 0.27 11.4 0.8 0.85 9.8 0.8 1.9 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Meis_PKNOX_N PF16493.5 CBY18971.1 - 9.3e-36 122.0 0.3 1.3e-35 121.6 0.3 1.2 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Peptidase_M13 PF01431.21 CBY18972.1 - 1.5e-66 223.9 0.1 2.5e-66 223.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CBY18972.1 - 4.4e-46 158.3 0.9 6e-46 157.8 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M13 VWA PF00092.28 CBY18974.1 - 3.9e-16 59.8 4.9 6.7e-16 59.0 4.9 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.27 CBY18974.1 - 1.4e-10 41.3 28.7 1.6e-06 28.3 9.9 3.2 3 0 0 3 3 3 2 EGF-like domain VWA_2 PF13519.6 CBY18974.1 - 1.8e-09 38.2 0.8 4.2e-09 37.0 0.8 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain hEGF PF12661.7 CBY18974.1 - 6.1e-05 23.5 17.4 0.00094 19.7 7.7 3.8 2 1 0 2 2 2 2 Human growth factor-like EGF VWA_CoxE PF05762.14 CBY18974.1 - 0.022 14.1 0.3 0.049 13.0 0.3 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Oxidored_nitro PF00148.19 CBY18974.1 - 0.13 11.0 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase PRCC PF10253.9 CBY18974.1 - 0.34 11.7 1.6 0.52 11.1 1.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting EGF_2 PF07974.13 CBY18974.1 - 5.4 7.5 36.7 0.39 11.1 10.4 3.9 4 0 0 4 4 4 0 EGF-like domain Zona_pellucida PF00100.23 CBY18975.1 - 8e-40 137.3 0.1 9.7e-40 137.0 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain P53 PF00870.18 CBY18975.1 - 0.17 11.6 0.9 0.43 10.3 0.9 1.6 1 1 0 1 1 1 0 P53 DNA-binding domain Vpu PF00558.19 CBY18976.1 - 0.013 15.3 0.1 0.013 15.3 0.1 1.0 1 0 0 1 1 1 0 Vpu protein MFS_1 PF07690.16 CBY18977.1 - 5e-05 22.4 36.4 0.00014 20.9 36.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_C50 PF03568.17 CBY18978.1 - 1.5e-11 44.1 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 CBY18978.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 CHAT domain Pan3_PK PF18101.1 CBY18978.1 - 0.093 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Peptidase_C50 PF03568.17 CBY18979.1 - 2.4e-09 36.8 0.0 4.3e-07 29.4 0.0 2.0 2 0 0 2 2 2 2 Peptidase family C50 Ax_dynein_light PF10211.9 CBY18980.1 - 6e-58 195.9 15.0 7e-58 195.7 15.0 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain DUF4763 PF15960.5 CBY18980.1 - 0.00083 18.7 10.7 0.0027 17.0 10.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) TSNAXIP1_N PF15739.5 CBY18980.1 - 0.0026 18.1 13.0 0.08 13.3 1.7 2.3 1 1 1 2 2 2 2 Translin-associated factor X-interacting N-terminus bZIP_2 PF07716.15 CBY18980.1 - 0.13 12.3 12.5 0.35 11.0 2.1 2.7 2 0 0 2 2 2 0 Basic region leucine zipper PI3K_P85_iSH2 PF16454.5 CBY18980.1 - 0.14 11.8 12.6 0.58 9.7 8.4 2.7 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FlaC_arch PF05377.11 CBY18980.1 - 0.16 12.4 7.2 7.3 7.1 0.3 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TEX13 PF15186.6 CBY18980.1 - 0.19 11.4 8.7 0.46 10.2 8.7 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DivIC PF04977.15 CBY18980.1 - 0.4 10.5 14.3 2.7 7.8 5.7 2.7 1 1 1 2 2 2 0 Septum formation initiator Occludin_ELL PF07303.13 CBY18980.1 - 0.65 10.8 8.3 0.23 12.2 4.3 2.1 2 1 1 3 3 3 0 Occludin homology domain DUF4200 PF13863.6 CBY18980.1 - 1.1 9.7 19.3 1.1 9.7 2.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) CLZ PF16526.5 CBY18980.1 - 1.4 9.3 15.3 2.5 8.5 0.2 3.6 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Allexi_40kDa PF05549.11 CBY18980.1 - 1.4 8.3 4.6 3.5 7.1 4.0 1.9 1 1 0 1 1 1 0 Allexivirus 40kDa protein LPP PF04728.13 CBY18980.1 - 1.8 9.1 6.2 3.3 8.2 0.6 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF724 PF05266.14 CBY18980.1 - 2.6 7.8 12.5 0.46 10.3 8.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF5320 PF17253.2 CBY18980.1 - 4.4 8.4 11.6 1.5 9.9 0.4 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5320) GrpE PF01025.19 CBY18980.1 - 4.4 6.9 13.8 0.45 10.2 7.1 2.5 2 2 1 3 3 3 0 GrpE DUF2203 PF09969.9 CBY18980.1 - 9.4 7.0 9.3 0.49 11.1 0.5 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) zf-C3Hc3H PF13891.6 CBY18981.1 - 6e-10 39.4 11.6 1.2e-08 35.2 1.3 2.7 3 0 0 3 3 3 2 Potential DNA-binding domain WRC PF08879.10 CBY18981.1 - 1.8 8.4 9.3 0.58 9.9 0.2 3.6 4 0 0 4 4 4 0 WRC Thioredoxin PF00085.20 CBY18982.1 - 3.9e-19 68.5 0.2 9.7e-19 67.3 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 CBY18982.1 - 6.7e-17 61.8 0.0 1.9e-16 60.3 0.0 1.9 1 0 0 1 1 1 1 Erv1 / Alr family FAD_SOX PF18371.1 CBY18982.1 - 3.9e-10 40.0 0.1 1.2e-09 38.4 0.1 2.0 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Thioredoxin_8 PF13905.6 CBY18982.1 - 0.00099 19.4 0.0 0.0035 17.6 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CBY18982.1 - 0.0042 16.9 0.1 0.0098 15.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 CBY18982.1 - 0.062 12.9 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 CBY18982.1 - 0.11 13.0 0.1 0.72 10.3 0.1 2.5 1 1 0 1 1 1 0 Thioredoxin-like domain zf-C2H2_jaz PF12171.8 CBY18982.1 - 0.16 12.3 0.6 0.43 10.9 0.6 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ANAPC10 PF03256.16 CBY18983.1 - 7.7e-54 182.1 0.1 9e-54 181.9 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CBY18983.1 - 2.7e-05 24.3 0.4 3.4e-05 24.0 0.4 1.1 1 0 0 1 1 1 1 F5/8 type C domain DUF1735 PF08522.10 CBY18983.1 - 0.063 13.9 0.0 0.096 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) FAIM1 PF06905.13 CBY18984.1 - 9.9e-60 201.2 0.3 1.2e-59 201.0 0.3 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Adenyl_transf PF04439.12 CBY18984.1 - 0.08 12.1 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Herpes_IR6 PF06307.12 CBY18984.1 - 0.15 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus IR6 protein SET PF00856.28 CBY18985.1 - 2.7e-09 37.6 0.0 6.2e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 SET domain AIG1 PF04548.16 CBY18985.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Vps39_1 PF10366.9 CBY18986.1 - 4.6e-19 68.7 0.4 4.6e-19 68.7 0.4 3.3 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CBY18986.1 - 2.6e-17 63.3 0.5 2.3e-16 60.2 0.0 2.9 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 CBY18986.1 - 1.8e-09 37.7 0.4 4.3e-09 36.4 0.4 1.7 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 CBY18986.1 - 3.4e-08 33.5 7.1 0.0025 17.7 0.1 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS LuxC PF05893.14 CBY18986.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) FlgI PF02119.16 CBY18986.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Flagellar P-ring protein Ras PF00071.22 CBY18987.1 - 6.5e-42 142.9 0.2 1.2e-27 96.5 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 CBY18987.1 - 1.1e-10 41.8 0.0 2.1e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY18987.1 - 0.00052 19.5 0.1 0.16 11.4 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY18987.1 - 0.0015 18.4 0.7 1.1 9.1 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CBY18987.1 - 0.051 13.4 0.0 2.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF1515 PF07439.11 CBY18987.1 - 0.073 13.1 0.1 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) RNA_helicase PF00910.22 CBY18987.1 - 0.085 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase G-alpha PF00503.20 CBY18987.1 - 0.15 11.2 0.0 9.8 5.2 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Bac_surface_Ag PF01103.23 CBY18989.1 - 4.1e-19 69.3 4.2 6e-19 68.7 4.2 1.2 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 CBY18989.1 - 0.019 14.4 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB zf-C2H2_4 PF13894.6 CBY18990.1 - 9.4e-06 26.0 22.5 0.014 16.1 1.6 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY18990.1 - 4.5e-05 23.7 18.7 0.00042 20.6 1.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY18990.1 - 0.0016 18.8 0.7 0.0016 18.8 0.7 4.0 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CBY18990.1 - 0.068 13.8 9.4 3.6 8.3 0.9 3.6 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 CBY18990.1 - 0.076 13.8 1.1 0.076 13.8 1.1 2.7 3 0 0 3 3 3 0 zinc-ribbon family zf-C2H2_2 PF12756.7 CBY18990.1 - 10 6.6 17.2 50 4.3 0.2 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) NT-C2 PF10358.9 CBY18991.1 - 1.2e-15 57.5 0.4 1.8e-15 56.9 0.4 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.30 CBY18991.1 - 7e-05 23.1 0.2 0.00022 21.5 0.0 1.8 2 0 0 2 2 2 1 C2 domain CEP209_CC5 PF16574.5 CBY18992.1 - 8.8e-34 116.4 14.7 8.8e-34 116.4 14.7 12.5 7 5 5 13 13 13 2 Coiled-coil region of centrosome protein CE290 TPR_MLP1_2 PF07926.12 CBY18992.1 - 0.002 18.2 10.3 0.002 18.2 10.3 15.1 5 4 9 15 15 15 3 TPR/MLP1/MLP2-like protein T3SSipB PF16535.5 CBY18992.1 - 0.0034 17.9 2.8 0.0034 17.9 2.8 9.3 5 4 3 8 8 8 1 Type III cell invasion protein SipB DUF3800 PF12686.7 CBY18992.1 - 2.4 8.8 16.4 3.4e+02 1.9 2.6 7.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) GalKase_gal_bdg PF10509.9 CBY18993.1 - 2.4e-19 68.6 0.2 5.4e-19 67.5 0.0 1.7 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CBY18993.1 - 4e-17 62.3 0.0 8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CBY18993.1 - 7.3e-12 45.3 0.1 1.6e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Zip PF02535.22 CBY18994.1 - 2.7e-70 237.2 12.6 2.7e-70 237.2 12.6 2.3 2 0 0 2 2 2 1 ZIP Zinc transporter DUF4602 PF15375.6 CBY18994.1 - 0.0031 17.8 0.2 0.0084 16.4 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) SARAF PF06682.12 CBY18994.1 - 0.023 14.4 2.0 0.045 13.4 0.0 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Orf78 PF06024.12 CBY18994.1 - 0.18 12.1 3.1 2.9 8.2 0.0 3.1 4 0 0 4 4 4 0 Orf78 (ac78) Serinc PF03348.15 CBY18994.1 - 0.19 10.6 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4834 PF16118.5 CBY18994.1 - 0.77 10.8 0.0 0.77 10.8 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) Pro-rich PF15240.6 CBY18994.1 - 1.9 8.8 6.3 0.2 11.9 0.5 2.0 2 0 0 2 2 2 0 Proline-rich FUSC_2 PF13515.6 CBY18994.1 - 5.3 7.2 11.2 1 9.5 5.0 3.0 4 0 0 4 4 4 0 Fusaric acid resistance protein-like TPR_MLP1_2 PF07926.12 CBY18996.1 - 0.0037 17.3 3.2 0.0069 16.4 3.2 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 CBY18996.1 - 0.016 15.2 0.7 0.026 14.6 0.7 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 CBY18996.1 - 0.025 15.0 3.0 0.048 14.1 3.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 CBY18996.1 - 0.12 12.1 1.9 0.23 11.3 1.9 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4094 PF13334.6 CBY18996.1 - 0.18 12.2 2.4 0.16 12.4 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) TSC22 PF01166.18 CBY18996.1 - 0.24 11.7 3.6 0.87 9.9 3.4 2.0 1 1 1 2 2 2 0 TSC-22/dip/bun family Dmrt1 PF12374.8 CBY18996.1 - 3.7 8.1 8.6 0.77 10.2 0.3 2.7 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 NYD-SP28_assoc PF14775.6 CBY18996.1 - 4.2 7.6 6.9 1.7 8.8 2.2 2.2 1 1 1 2 2 2 0 Sperm tail C-terminal domain RhoGAP PF00620.27 CBY18998.1 - 4.1e-05 23.4 1.0 0.0024 17.7 0.1 2.6 2 0 0 2 2 2 1 RhoGAP domain Cortex-I_coil PF09304.10 CBY18998.1 - 0.0032 17.7 5.2 0.011 15.9 1.5 2.7 1 1 1 2 2 2 1 Cortexillin I, coiled coil THP2 PF09432.10 CBY18998.1 - 0.017 15.2 2.4 0.017 15.2 2.4 2.3 2 1 0 2 2 2 0 Tho complex subunit THP2 TFIIE_alpha PF02002.17 CBY18998.1 - 0.037 13.9 0.5 0.46 10.4 0.1 2.6 2 0 0 2 2 2 0 TFIIE alpha subunit Plk4_PB2 PF18409.1 CBY18998.1 - 7.2 7.3 8.3 7.9 7.2 2.9 3.1 2 2 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 Arf PF00025.21 CBY18999.1 - 6e-78 260.3 0.4 6.8e-78 260.1 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY18999.1 - 2.1e-15 57.0 0.1 3e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBY18999.1 - 7.6e-14 51.5 0.0 9.3e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBY18999.1 - 1.6e-13 50.6 0.0 1.9e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY18999.1 - 2.6e-13 49.9 1.2 2.6e-09 36.7 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY18999.1 - 2.9e-10 39.9 0.0 3.4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY18999.1 - 2.5e-06 27.6 0.0 4.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBY18999.1 - 0.0052 16.1 0.2 0.0066 15.8 0.2 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CbiA PF01656.23 CBY18999.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArfGap PF01412.18 CBY19000.1 - 1.1e-07 31.9 0.6 0.001 19.2 0.0 2.9 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf TPT PF03151.16 CBY19001.1 - 1.5e-20 73.7 16.3 1.7e-20 73.5 16.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY19001.1 - 9.6e-07 29.1 22.5 4.4e-05 23.7 6.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family Diphthamide_syn PF01866.17 CBY19002.1 - 6.2e-55 186.8 0.0 2.6e-54 184.7 0.0 1.8 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Cornichon PF03311.14 CBY19003.1 - 3.8e-38 130.5 5.1 4.4e-38 130.4 5.1 1.0 1 0 0 1 1 1 1 Cornichon protein Abhydrolase_2 PF02230.16 CBY19004.1 - 1.2e-60 205.0 0.0 1.4e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CBY19004.1 - 8.1e-12 44.9 0.0 0.00015 21.1 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 CBY19004.1 - 1.1e-08 35.0 0.0 5.3e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CBY19004.1 - 1.5e-08 34.5 0.0 6.7e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CBY19004.1 - 1.1e-07 31.5 0.1 0.028 13.9 0.0 3.0 2 1 1 3 3 3 2 Prolyl oligopeptidase family Esterase PF00756.20 CBY19004.1 - 2.6e-06 27.3 0.0 4.4e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Putative esterase Abhydrolase_1 PF00561.20 CBY19004.1 - 1.5e-05 24.8 0.4 0.01 15.5 0.2 2.8 1 1 1 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 CBY19004.1 - 0.00015 20.4 0.0 0.00028 19.5 0.0 1.4 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 CBY19004.1 - 0.00035 20.5 0.0 0.093 12.6 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY19004.1 - 0.00082 20.0 0.0 0.0015 19.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CBY19004.1 - 0.0024 17.7 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.9 CBY19004.1 - 0.0039 16.7 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase BAAT_C PF08840.11 CBY19004.1 - 0.0069 16.3 0.0 9.2 6.1 0.1 3.0 2 1 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 CBY19004.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.12 CBY19004.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Palm_thioest PF02089.15 CBY19004.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Cutinase PF01083.22 CBY19004.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_4 PF08386.10 CBY19004.1 - 0.2 11.8 0.0 0.46 10.6 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein NUDIX PF00293.28 CBY19006.1 - 1.3e-07 31.7 0.0 2.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_CG PF14542.6 CBY19006.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase SNF2_N PF00176.23 CBY19007.1 - 1.6e-48 165.2 0.8 2.6e-48 164.5 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY19007.1 - 7.7e-19 68.1 0.0 1.8e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 CBY19007.1 - 1.7e-07 31.5 0.7 2.1e-06 28.1 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 CBY19007.1 - 5.8e-05 23.2 0.5 0.0021 18.1 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CBY19007.1 - 0.00098 19.3 0.4 0.0037 17.4 0.4 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 CBY19007.1 - 0.062 13.3 0.0 0.062 13.3 0.0 2.9 4 0 0 4 4 4 0 SLIDE RuvB_N PF05496.12 CBY19007.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Chromo PF00385.24 CBY19008.1 - 4e-23 81.1 7.1 1.2e-11 44.3 0.1 3.0 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain FliW PF02623.15 CBY19008.1 - 0.089 12.7 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 FliW protein TTL PF03133.15 CBY19009.1 - 6.9e-38 130.4 0.8 1.3e-37 129.6 0.8 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Glyco_tran_28_C PF04101.16 CBY19010.1 - 2.3e-23 83.0 0.0 2.8e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Clathrin PF00637.20 CBY19011.1 - 6.5e-196 642.1 37.2 1e-33 116.2 1.6 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CBY19011.1 - 4.4e-41 137.2 4.0 2.9e-07 30.5 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 CBY19011.1 - 8.2e-29 99.3 4.4 1.2e-28 98.8 0.8 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 CBY19011.1 - 3.4e-10 39.1 0.0 1e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 CBY19011.1 - 0.00025 20.2 2.9 0.24 10.4 0.0 3.7 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 CBY19011.1 - 0.02 14.9 9.0 3.9 7.7 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RtcR PF06956.11 CBY19011.1 - 0.031 13.7 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Regulator of RNA terminal phosphate cyclase TPR_12 PF13424.6 CBY19011.1 - 0.051 13.9 2.7 41 4.5 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY19011.1 - 0.14 12.4 9.9 0.46 10.8 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY19011.1 - 0.22 11.8 5.3 26 5.2 0.0 5.1 4 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CBY19011.1 - 5.4 7.8 6.4 1.6e+02 3.0 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat UMP1 PF05348.11 CBY19013.1 - 3.1e-05 24.2 0.0 3.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 CLASP_N PF12348.8 CBY19014.1 - 1e-29 103.8 2.6 6.8e-27 94.5 3.0 2.9 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 CBY19014.1 - 7.5e-06 25.8 16.4 2.7 8.5 0.0 9.2 10 0 0 10 10 10 2 HEAT repeat Cnd1 PF12717.7 CBY19014.1 - 6.4e-05 23.0 4.2 0.034 14.2 0.6 4.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBY19014.1 - 8.2e-05 21.4 11.5 0.49 8.9 2.1 5.7 4 2 0 6 6 6 3 Adaptin N terminal region HEAT_2 PF13646.6 CBY19014.1 - 0.021 15.2 10.6 3.2 8.2 0.0 6.4 6 1 2 8 8 8 0 HEAT repeats IBN_N PF03810.19 CBY19014.1 - 0.037 13.9 0.3 1.9 8.5 0.0 3.0 2 0 0 2 2 2 0 Importin-beta N-terminal domain HYLS1_C PF15311.6 CBY19015.1 - 9.8e-26 90.3 1.1 9.8e-26 90.3 1.1 1.8 2 0 0 2 2 2 1 Hydrolethalus syndrome protein 1 C-terminus DUF2510 PF10708.9 CBY19015.1 - 0.048 13.4 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) IPP-2 PF04979.14 CBY19017.1 - 7.6e-23 81.7 10.2 1.4e-22 80.8 10.2 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) MRP-S23 PF10484.9 CBY19017.1 - 0.062 13.6 1.4 0.34 11.2 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 NARP1 PF12569.8 CBY19018.1 - 0.065 12.1 20.8 0.12 11.2 20.8 1.6 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pkinase PF00069.25 CBY19019.1 - 4.8e-72 242.5 0.0 7e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19019.1 - 2.3e-35 122.1 0.0 3.8e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY19019.1 - 2.1e-05 23.6 0.1 4.1e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY19019.1 - 0.0011 17.8 0.0 0.01 14.6 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CBY19019.1 - 0.0049 16.2 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBY19019.1 - 0.026 14.4 0.0 0.083 12.8 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family 2OG-FeII_Oxy_2 PF13532.6 CBY19020.1 - 1.2e-28 100.7 0.0 1.4e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.9 CBY19020.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase 2OG-FeII_Oxy_2 PF13532.6 CBY19021.1 - 8.3e-12 45.7 0.0 9.2e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NMT_C PF02799.15 CBY19022.1 - 9.2e-77 257.3 0.0 1.5e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CBY19022.1 - 1.1e-73 246.4 0.0 1.8e-73 245.6 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 CBY19022.1 - 0.00091 19.5 0.0 0.0026 18.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 CBY19022.1 - 0.068 13.2 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY19022.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pox_F16 PF04708.12 CBY19022.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus F16 protein NMT_C PF02799.15 CBY19023.1 - 2.4e-76 255.9 0.3 5.4e-76 254.8 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain RasGEF PF00617.19 CBY19023.1 - 6.9e-23 81.7 1.9 2.1e-22 80.2 0.9 2.2 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CBY19023.1 - 1.7e-06 28.2 0.2 4.6e-06 26.8 0.2 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Aida_N PF08910.10 CBY19023.1 - 0.2 12.1 0.7 0.8 10.1 0.0 2.4 2 0 0 2 2 2 0 Aida N-terminus RasGEF PF00617.19 CBY19024.1 - 3.3e-36 125.1 1.3 1.3e-35 123.2 0.2 2.5 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CBY19024.1 - 1.6e-06 28.3 0.1 6e-06 26.4 0.1 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif Aida_N PF08910.10 CBY19024.1 - 0.69 10.3 0.0 0.69 10.3 0.0 2.5 3 0 0 3 3 3 0 Aida N-terminus DEAD PF00270.29 CBY19026.1 - 6.9e-47 159.5 0.3 1.8e-46 158.1 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY19026.1 - 5.7e-24 84.6 0.1 1.2e-22 80.3 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBY19026.1 - 1e-18 67.3 0.0 2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBY19026.1 - 3.2e-08 33.8 0.1 6.9e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA-synt_1 PF00133.22 CBY19027.1 - 1.1e-41 142.8 0.1 4.5e-41 140.8 0.1 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CBY19027.1 - 2.2e-18 66.2 0.1 1.8e-11 43.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CBY19027.1 - 2.1e-11 44.0 0.0 5.1e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CBY19027.1 - 2.2e-08 33.8 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF563 PF04577.14 CBY19027.1 - 0.0064 16.6 0.0 4.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF563) tRNA-synt_1f PF01921.18 CBY19027.1 - 0.0078 15.2 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (K) Rad51 PF08423.11 CBY19028.1 - 5.5e-102 340.4 0.0 8.6e-102 339.8 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBY19028.1 - 1.3e-11 44.5 0.1 1.9e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CBY19028.1 - 8e-08 31.9 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.6 CBY19028.1 - 5.9e-06 26.8 2.2 1.3e-05 25.7 1.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.6 CBY19028.1 - 0.0001 21.9 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY19028.1 - 0.0016 18.2 0.2 0.0063 16.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CBY19028.1 - 0.0032 17.9 0.0 0.0084 16.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NRD1_2 PF01995.16 CBY19028.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 2 0 0 2 2 2 0 NrpR regulatory domains NRD1 and 2 Ketoacyl-synt_C PF02801.22 CBY19028.1 - 0.06 13.4 0.1 9.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain HA70_C PF17993.1 CBY19029.1 - 0.031 14.3 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain MafB19-deam PF14437.6 CBY19030.1 - 5.6e-05 22.9 0.0 6.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 CBY19030.1 - 0.00017 21.4 0.0 0.00017 21.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Pkinase PF00069.25 CBY19031.1 - 1e-60 205.3 0.0 9.1e-60 202.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19031.1 - 8.2e-29 100.7 0.3 1.8e-22 79.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY19031.1 - 8.2e-06 25.3 0.6 0.00084 18.7 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 CBY19031.1 - 0.00033 19.7 0.2 0.0007 18.6 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 CBY19031.1 - 0.00087 20.0 0.3 0.0019 18.8 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 CBY19031.1 - 0.00099 19.1 0.2 0.04 13.9 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY19031.1 - 0.0082 15.5 0.1 0.021 14.2 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CBY19031.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Phosducin PF02114.16 CBY19032.1 - 3.3e-13 49.2 0.1 7.6e-13 48.0 0.0 1.4 1 1 0 1 1 1 1 Phosducin DUF4751 PF15942.5 CBY19032.1 - 0.13 12.2 0.4 0.59 10.1 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4751) NPV_P10 PF05531.12 CBY19033.1 - 0.016 15.7 5.2 0.11 12.9 0.3 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IL31 PF15209.6 CBY19033.1 - 0.045 13.5 1.3 0.14 12.0 1.3 1.9 1 0 0 1 1 1 0 Interleukin 31 DUF3105 PF11303.8 CBY19033.1 - 0.085 13.0 1.0 0.2 11.8 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) DUF4806 PF16064.5 CBY19033.1 - 0.14 12.5 4.5 11 6.4 0.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4806) Folliculin PF11704.8 CBY19033.1 - 1.3 8.9 5.5 3.3 7.5 5.5 1.9 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport IQ PF00612.27 CBY19034.1 - 2.8e-05 23.5 0.5 5.3e-05 22.7 0.5 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dpy-30 PF05186.13 CBY19034.1 - 0.019 14.7 0.2 0.13 12.0 0.2 2.2 2 0 0 2 2 2 0 Dpy-30 motif CRM1_C PF08767.11 CBY19035.1 - 0.00024 20.4 0.1 0.00085 18.6 0.1 1.9 1 0 0 1 1 1 1 CRM1 C terminal IBN_N PF03810.19 CBY19035.1 - 0.0005 19.9 0.1 0.0026 17.6 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF1275 PF06912.11 CBY19035.1 - 0.0013 18.7 0.1 0.18 11.7 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1275) Dynein_light PF01221.18 CBY19036.1 - 1e-41 141.1 0.4 1.2e-41 140.9 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Tubulin PF00091.25 CBY19037.1 - 1.2e-48 166.0 1.6 1.2e-48 165.9 0.3 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 CBY19037.1 - 0.00021 21.0 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBY19037.1 - 0.001 18.3 0.3 0.0022 17.2 0.0 1.7 2 0 0 2 2 2 1 Tubulin like MBF1 PF08523.10 CBY19038.1 - 8.5e-21 74.2 2.7 1.8e-20 73.1 2.7 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CBY19038.1 - 6.4e-13 48.5 0.3 1.1e-12 47.8 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 CBY19038.1 - 0.00024 21.1 0.9 0.00041 20.3 0.9 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 CBY19038.1 - 0.009 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Cyclin_N PF00134.23 CBY19039.1 - 1.6e-22 79.6 1.2 1.8e-22 79.4 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY19039.1 - 8.4e-05 22.6 0.1 0.00023 21.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain zf-HC5HC2H PF13771.6 CBY19040.1 - 4e-11 43.0 9.6 4e-11 43.0 9.6 5.1 4 2 0 4 4 4 1 PHD-like zinc-binding domain zf-RING_2 PF13639.6 CBY19040.1 - 0.44 10.9 44.1 0.076 13.4 6.2 4.9 5 1 0 5 5 5 0 Ring finger domain JmjC PF02373.22 CBY19043.1 - 6.9e-24 84.5 0.5 1.9e-23 83.1 0.0 2.0 3 0 0 3 3 3 1 JmjC domain, hydroxylase AraC_binding PF02311.19 CBY19043.1 - 0.041 13.8 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_2 PF07883.11 CBY19043.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Lipase PF00151.19 CBY19045.1 - 8.3e-47 160.1 0.1 1.6e-46 159.2 0.1 1.3 1 1 0 1 1 1 1 Lipase DUF900 PF05990.12 CBY19045.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) C2 PF00168.30 CBY19046.1 - 3.9e-47 158.8 0.1 2.8e-24 85.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CBY19046.1 - 0.0011 18.6 0.0 0.16 11.5 0.0 2.3 1 1 1 2 2 2 2 CEP76 C2 domain MFS_1 PF07690.16 CBY19046.1 - 0.0027 16.7 14.1 0.036 13.0 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.6 CBY19047.1 - 8.9e-14 51.6 6.9 1.5e-13 50.9 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY19047.1 - 5.3e-10 39.0 6.6 8.4e-10 38.3 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY19047.1 - 4.9e-08 33.1 3.5 1.1e-07 32.0 3.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBY19047.1 - 7.1e-08 32.2 7.2 1.2e-07 31.5 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY19047.1 - 1.2e-07 31.6 1.9 1.2e-07 31.6 1.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY19047.1 - 2e-07 30.9 4.6 3.2e-07 30.2 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY19047.1 - 5.2e-07 29.4 3.2 8.2e-07 28.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY19047.1 - 6e-07 29.1 1.2 6e-07 29.1 1.2 2.4 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 CBY19047.1 - 6.5e-05 22.7 7.2 0.0015 18.3 8.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBY19047.1 - 0.0003 20.3 2.6 0.00059 19.4 2.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CBY19047.1 - 0.034 14.2 2.7 0.1 12.6 2.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CBY19047.1 - 0.044 13.9 4.4 0.1 12.7 4.4 1.6 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 CBY19047.1 - 0.33 10.8 2.6 0.72 9.7 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 CBY19047.1 - 1.7 8.7 4.0 12 5.9 0.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 CBY19047.1 - 1.8 8.4 4.9 3.8 7.4 4.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 CBY19047.1 - 2.3 8.6 5.9 6.2 7.2 5.9 1.7 1 1 0 1 1 1 0 RING-like domain Trypsin PF00089.26 CBY19048.1 - 5.5e-47 160.4 0.1 8e-47 159.9 0.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY19048.1 - 0.00013 22.9 0.2 0.0014 19.6 0.2 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain IRF PF00605.17 CBY19049.1 - 6.2e-40 135.7 0.1 1.2e-39 134.8 0.1 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 CBY19049.1 - 3.1e-09 36.9 0.0 5.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DSS1_SEM1 PF05160.13 CBY19050.1 - 8.6e-21 73.8 21.3 1.1e-20 73.4 21.3 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family UPF0220 PF05255.11 CBY19051.1 - 6.9e-36 123.3 1.2 9.6e-36 122.8 1.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) PigN PF04987.14 CBY19052.1 - 6.8e-61 206.5 54.2 1.1e-60 205.8 54.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CBY19052.1 - 1.2e-10 41.6 0.1 4.5e-07 29.8 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CBY19052.1 - 4.1e-06 26.4 0.1 5.6e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CBY19052.1 - 0.00066 19.1 0.2 0.0012 18.3 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 CBY19052.1 - 0.04 12.9 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Fes1 PF08609.10 CBY19053.1 - 1e-05 26.3 7.0 1.6e-05 25.7 4.8 2.4 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 Ribosomal_S2 PF00318.20 CBY19054.1 - 6.4e-29 100.7 0.2 7.3e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S2 TPR_12 PF13424.6 CBY19055.1 - 6.4e-24 84.1 11.8 5.9e-10 39.3 0.6 5.7 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 CBY19055.1 - 2e-17 62.5 1.0 8.8e-06 25.4 0.0 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBY19055.1 - 8.5e-07 28.5 6.1 0.03 14.2 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBY19055.1 - 1.6e-05 24.6 1.5 0.076 13.1 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY19055.1 - 2.6e-05 24.0 12.8 2.5 8.4 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY19055.1 - 2.6e-05 23.8 5.7 0.09 12.1 0.1 3.5 2 2 1 4 4 4 2 MalT-like TPR region TPR_19 PF14559.6 CBY19055.1 - 0.00036 21.0 5.6 0.0058 17.1 0.0 4.8 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY19055.1 - 0.0019 18.3 9.4 1.2 9.5 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 CBY19055.1 - 0.024 14.6 8.8 3.9 7.6 1.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5596 PF18082.1 CBY19055.1 - 0.17 11.8 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) PPR PF01535.20 CBY19055.1 - 0.22 11.8 1.0 7.8 7.0 0.0 4.1 5 0 0 5 5 5 0 PPR repeat RNaseH_pPIWI_RE PF13032.6 CBY19056.1 - 0.096 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE Exo_endo_phos_2 PF14529.6 CBY19057.1 - 0.00011 22.0 0.7 0.00079 19.3 0.5 2.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CBY19057.1 - 0.00024 20.7 0.1 0.00083 18.9 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CH PF00307.31 CBY19058.1 - 0.041 14.1 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 Calponin homology (CH) domain Nif11 PF07862.11 CBY19058.1 - 0.045 14.1 0.1 0.097 13.0 0.0 1.6 2 0 0 2 2 2 0 Nif11 domain Abhydrolase_5 PF12695.7 CBY19058.1 - 0.065 13.0 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family fn3 PF00041.21 CBY19059.1 - 4.6e-22 78.2 9.8 6.9e-08 32.7 0.0 7.4 7 2 0 7 7 7 5 Fibronectin type III domain Gly_rich PF12810.7 CBY19059.1 - 0.3 11.0 56.8 22 4.9 56.8 2.5 1 1 0 1 1 1 0 Glycine rich protein cNMP_binding PF00027.29 CBY19061.1 - 6.5e-42 141.5 0.0 1.5e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 CBY19061.1 - 0.21 10.9 2.6 3.7 6.8 0.2 2.5 2 1 0 2 2 2 0 Protein kinase domain DUF3783 PF12646.7 CBY19061.1 - 0.21 11.5 1.0 2.1 8.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) 7TMR-HDED PF07697.11 CBY19061.1 - 8.5 6.4 11.4 0.42 10.7 0.8 2.8 2 1 1 3 3 3 0 7TM-HD extracellular Slx4 PF09494.10 CBY19065.1 - 0.08 12.9 0.4 0.59 10.1 0.1 2.4 2 0 0 2 2 2 0 Slx4 endonuclease LptF_LptG PF03739.14 CBY19065.1 - 0.18 10.6 1.1 0.26 10.1 1.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Sulfotransfer_1 PF00685.27 CBY19066.1 - 5.5e-13 49.0 0.0 8.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY19066.1 - 0.00051 20.5 0.0 0.085 13.2 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY19067.1 - 1e-09 38.3 0.0 1.1e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Galactosyl_T PF01762.21 CBY19068.1 - 2e-34 119.1 0.0 2.9e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF3939 PF13075.6 CBY19068.1 - 0.02 14.9 0.0 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) Fringe PF02434.16 CBY19068.1 - 0.067 12.6 0.4 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 Fringe-like BPS PF08947.10 CBY19068.1 - 0.12 12.2 0.1 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 BPS (Between PH and SH2) HMMR_N PF15905.5 CBY19069.1 - 0.00023 20.7 14.9 0.00023 20.7 14.9 5.9 2 1 4 6 6 6 4 Hyaluronan mediated motility receptor N-terminal Trypan_PARP PF05887.11 CBY19069.1 - 0.0073 16.3 11.9 0.03 14.3 11.9 2.0 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) APG6_N PF17675.1 CBY19069.1 - 0.012 16.1 18.0 0.012 16.1 18.0 7.5 1 1 4 5 5 5 0 Apg6 coiled-coil region Rad10 PF03834.14 CBY19070.1 - 3e-31 107.8 0.1 7.3e-31 106.5 0.1 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CBY19070.1 - 0.00011 22.7 0.4 0.00028 21.4 0.4 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 CBY19070.1 - 0.0043 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 CBY19070.1 - 0.013 16.1 0.3 0.91 10.2 0.0 3.3 2 1 2 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 CBY19070.1 - 0.09 12.7 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4515 PF14988.6 CBY19071.1 - 5.1e-55 186.5 39.8 5.1e-55 186.5 39.8 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4515) Sec34 PF04136.15 CBY19071.1 - 0.36 10.7 25.7 0.098 12.5 3.7 3.3 2 2 1 3 3 3 0 Sec34-like family DUF948 PF06103.11 CBY19071.1 - 6.8 7.0 11.0 0.16 12.2 1.3 2.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Pkinase_Tyr PF07714.17 CBY19072.1 - 1.5e-73 247.3 0.0 1.8e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY19072.1 - 9.5e-39 133.3 0.0 1.2e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY19072.1 - 0.00032 20.1 0.0 0.0018 17.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY19072.1 - 0.076 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Fer2 PF00111.27 CBY19073.1 - 3.3e-09 36.6 0.5 4.3e-09 36.2 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4749 PF15936.5 CBY19074.1 - 0.27 12.4 0.2 0.27 12.4 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4749) UDPGP PF01704.18 CBY19075.1 - 2.9e-191 635.5 0.7 3.6e-191 635.2 0.7 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 CBY19075.1 - 0.033 13.0 0.2 2.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Sulfotransfer_2 PF03567.14 CBY19076.1 - 8.8e-44 150.3 4.6 1e-43 150.1 4.6 1.0 1 0 0 1 1 1 1 Sulfotransferase family zf-H2C2_2 PF13465.6 CBY19077.1 - 2.9e-19 68.6 19.3 2.4e-08 34.0 1.2 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY19077.1 - 6.5e-16 57.8 17.5 1.5e-05 25.2 1.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY19077.1 - 4.1e-10 39.6 17.4 0.00068 20.3 1.5 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY19077.1 - 5.1e-07 29.5 15.8 0.0065 16.4 2.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY19077.1 - 6e-06 26.5 8.3 4e-05 23.8 0.9 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-MYST PF17772.1 CBY19077.1 - 0.0036 16.9 3.2 0.21 11.2 0.1 2.8 2 1 1 3 3 3 1 MYST family zinc finger domain C1_4 PF07975.12 CBY19077.1 - 0.0059 16.8 3.3 3.9 7.8 2.3 2.5 2 0 0 2 2 2 2 TFIIH C1-like domain OSTMP1 PF09777.9 CBY19077.1 - 0.031 13.7 1.4 0.051 13.0 1.4 1.3 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2H2_8 PF15909.5 CBY19077.1 - 0.11 12.9 8.5 1.6 9.1 6.5 2.5 1 1 2 3 3 3 0 C2H2-type zinc ribbon Scramblase PF03803.15 CBY19077.1 - 0.14 11.5 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Scramblase Zn-ribbon_8 PF09723.10 CBY19077.1 - 0.15 12.2 4.5 5 7.3 1.4 2.8 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 CBY19077.1 - 0.25 11.7 0.1 0.25 11.7 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY19077.1 - 0.27 11.6 10.5 0.25 11.7 0.5 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2757 PF10955.8 CBY19077.1 - 2.1 8.7 4.4 3.6 7.9 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) zf-C2H2_11 PF16622.5 CBY19077.1 - 2.3 8.0 12.4 0.73 9.7 0.3 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf_UBZ PF18439.1 CBY19077.1 - 2.5 7.7 7.2 5.4 6.7 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PHD PF00628.29 CBY19077.1 - 2.6 8.0 8.9 9.3 6.2 2.5 2.4 1 1 1 2 2 2 0 PHD-finger zf-C2HE PF16278.5 CBY19077.1 - 3.1 8.3 17.3 1.6 9.2 2.8 3.4 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 CBY19077.1 - 3.7 7.3 6.3 1.4 8.6 2.1 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 CBY19077.1 - 4.7 7.3 10.5 0.083 12.9 1.3 2.6 1 1 2 3 3 3 0 BED zinc finger Ferritin PF00210.24 CBY19078.1 - 3.2e-18 66.0 0.8 2.6e-17 63.1 0.7 1.9 1 1 0 2 2 2 1 Ferritin-like domain Rubrerythrin PF02915.17 CBY19078.1 - 1e-05 26.0 0.9 1.7e-05 25.2 0.9 1.4 1 0 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.10 CBY19078.1 - 0.074 13.4 0.2 4 7.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) FCH PF00611.23 CBY19078.1 - 0.17 12.2 0.6 0.83 10.0 0.2 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Isochorismatase PF00857.20 CBY19079.1 - 4e-23 82.5 0.2 5.7e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 Isochorismatase family MAF_flag10 PF01973.18 CBY19079.1 - 0.048 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 zf-C3HC4_3 PF13920.6 CBY19080.1 - 1.3e-07 31.4 8.1 2.4e-07 30.5 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY19080.1 - 1.2e-06 28.3 10.1 2.4e-06 27.3 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY19080.1 - 9.8e-06 25.3 10.7 2.1e-05 24.2 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY19080.1 - 2.9e-05 24.3 10.2 6.1e-05 23.3 10.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBY19080.1 - 0.0022 17.9 9.6 0.0061 16.5 9.4 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBY19080.1 - 0.053 13.8 8.7 0.21 11.9 8.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CBY19080.1 - 0.11 12.7 9.5 0.42 10.8 9.5 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CBY19080.1 - 0.33 11.0 9.0 0.43 10.6 6.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBY19080.1 - 0.8 9.8 4.8 1.5 9.0 4.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBY19080.1 - 1.1 9.2 9.7 4.5 7.2 9.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 YdjO PF14169.6 CBY19080.1 - 1.6 8.6 3.9 1.1 9.0 0.3 2.3 1 1 1 2 2 2 0 Cold-inducible protein YdjO zf-Nse PF11789.8 CBY19080.1 - 2 8.3 6.5 5.1 7.0 6.5 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Sec15 PF04091.12 CBY19081.1 - 3e-46 158.3 3.5 4.4e-46 157.8 0.1 2.5 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 CBY19081.1 - 0.0069 16.6 1.1 0.0069 16.6 1.1 3.0 2 1 0 2 2 2 1 Golgi transport complex subunit 5 DUF592 PF04574.13 CBY19081.1 - 0.033 14.0 0.3 0.033 14.0 0.3 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF592) TnpV PF14198.6 CBY19081.1 - 0.35 10.9 9.6 0.21 11.6 0.4 3.6 3 1 0 3 3 3 0 Transposon-encoded protein TnpV Sec8_exocyst PF04048.14 CBY19081.1 - 0.67 9.8 9.9 0.34 10.8 1.2 3.9 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain WD40 PF00400.32 CBY19082.1 - 3.3e-12 46.7 8.7 7.3e-05 23.5 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY19082.1 - 1.5e-07 31.6 1.1 6.8e-06 26.3 0.2 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY19082.1 - 4.4e-05 22.3 1.3 0.00046 19.0 0.9 2.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 CBY19082.1 - 0.00055 19.9 0.5 0.082 12.8 0.1 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY19082.1 - 0.001 18.5 1.3 0.0057 16.0 0.1 2.4 2 1 1 3 3 3 1 WD40-like domain Utp8 PF10395.9 CBY19082.1 - 0.0099 14.4 0.1 0.11 10.9 0.1 2.0 1 1 0 1 1 1 1 Utp8 family Vps16_N PF04841.13 CBY19082.1 - 0.013 14.3 0.2 0.019 13.8 0.2 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region Nucleoporin_N PF08801.11 CBY19082.1 - 0.08 11.7 0.1 4.1 6.0 0.0 2.4 1 1 1 2 2 2 0 Nup133 N terminal like Hira PF07569.11 CBY19082.1 - 0.15 11.7 4.7 2 8.1 3.2 2.6 1 1 1 2 2 2 0 TUP1-like enhancer of split Mito_carr PF00153.27 CBY19083.1 - 6.9e-11 41.9 0.5 2.1e-10 40.4 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial carrier protein Mito_carr PF00153.27 CBY19084.1 - 2e-18 66.1 1.1 5.8e-12 45.4 0.0 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein AMP-binding PF00501.28 CBY19085.1 - 1.4e-26 93.1 0.0 4e-14 52.1 0.0 3.7 3 1 0 3 3 3 3 AMP-binding enzyme PP2C PF00481.21 CBY19087.1 - 3.4e-56 190.7 0.0 5e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY19087.1 - 6.6e-07 29.2 0.0 3e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C CARD_2 PF16739.5 CBY19087.1 - 0.17 11.9 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain Aa_trans PF01490.18 CBY19088.1 - 1.3e-28 99.8 16.1 1.6e-28 99.6 16.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ndc1_Nup PF09531.10 CBY19088.1 - 1.6 7.3 6.3 2 7.0 6.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EGF_CA PF07645.15 CBY19089.1 - 3.3e-08 33.6 8.2 3.3e-08 33.6 8.2 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 CBY19089.1 - 0.0046 16.9 0.6 0.0046 16.9 0.6 2.1 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY19089.1 - 0.006 16.7 7.0 0.006 16.7 7.0 2.3 2 0 0 2 2 2 1 EGF domain DHC_N1 PF08385.12 CBY19090.1 - 6.1e-144 480.7 13.1 6.1e-144 480.7 13.1 3.4 3 1 0 3 3 3 3 Dynein heavy chain, N-terminal region 1 KMP11 PF03037.16 CBY19090.1 - 6.1 7.7 9.4 26 5.7 0.1 4.1 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 DHC_N2 PF08393.13 CBY19091.1 - 4.1e-84 283.0 9.9 2.4e-80 270.6 0.2 2.4 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 Sugarporin_N PF11471.8 CBY19091.1 - 0.11 12.4 0.5 0.23 11.4 0.5 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension AAA_6 PF12774.7 CBY19092.1 - 8.7e-109 363.4 0.0 1.2e-108 363.0 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 CBY19092.1 - 1.6e-12 47.6 2.7 1.1e-07 32.0 0.1 2.9 2 1 1 3 3 3 2 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBY19092.1 - 1.3e-06 28.4 0.0 0.00046 20.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY19092.1 - 1.8e-06 27.6 0.7 0.0014 18.2 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 CBY19092.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 CBY19092.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBY19092.1 - 0.095 13.2 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CBY19092.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.9 CBY19092.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF853 PF05872.12 CBY19092.1 - 0.15 10.6 0.2 0.22 10.1 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_8 PF12780.7 CBY19093.1 - 6.2e-109 363.3 0.0 1.6e-108 361.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBY19093.1 - 1.4e-63 214.0 0.5 1.4e-63 214.0 0.5 3.0 4 0 0 4 4 4 1 ATP-binding dynein motor region MT PF12777.7 CBY19093.1 - 4.6e-56 190.3 12.2 4.6e-56 190.3 12.2 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CBY19093.1 - 1e-47 161.1 0.0 2.8e-42 143.6 0.0 2.8 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CBY19093.1 - 6e-29 101.0 3.6 1.2e-20 73.9 0.6 2.8 2 1 1 3 3 3 2 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 CBY19093.1 - 1.6e-25 89.7 0.1 4.5e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_1 PF17857.1 CBY19093.1 - 4.9e-23 81.2 0.4 2e-22 79.3 0.4 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBY19093.1 - 0.0026 17.7 0.0 2.1 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Exonuc_VII_L PF02601.15 CBY19093.1 - 0.27 10.8 12.0 2.4 7.7 0.4 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Cas6 PF09559.10 CBY19093.1 - 0.43 10.5 6.6 1.6 8.7 0.3 2.4 2 0 0 2 2 2 0 Cas6 Crispr Atg14 PF10186.9 CBY19093.1 - 3.8 6.5 11.8 0.22 10.6 3.9 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 CBY19093.1 - 6.8 7.0 6.6 1.2 9.4 0.2 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-RING_2 PF13639.6 CBY19094.1 - 1.1e-10 41.6 11.9 1.6e-09 37.9 7.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CBY19094.1 - 2.2e-07 31.1 4.3 2.2e-07 31.1 4.3 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY19094.1 - 3.8e-07 30.0 7.7 3.8e-07 30.0 7.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBY19094.1 - 5.9e-07 29.5 4.4 2.7e-06 27.4 1.8 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CBY19094.1 - 1.5e-06 27.8 10.6 2.1e-05 24.1 5.0 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBY19094.1 - 2.1e-06 27.5 8.8 2.1e-06 27.5 8.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY19094.1 - 3.5e-06 26.9 7.5 5.2e-06 26.4 2.0 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY19094.1 - 2.7e-05 23.9 6.3 2.7e-05 23.9 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY19094.1 - 0.00013 21.8 9.2 0.00013 21.8 9.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBY19094.1 - 0.00022 20.8 5.3 0.00022 20.8 5.3 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 CBY19094.1 - 0.0016 18.3 5.2 0.0016 18.3 5.2 1.7 2 0 0 2 2 1 1 PHD-finger Prok-RING_4 PF14447.6 CBY19094.1 - 0.003 17.4 6.2 0.003 17.4 6.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 IQ PF00612.27 CBY19094.1 - 0.0041 16.8 0.7 0.011 15.5 0.7 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-HC5HC2H_2 PF13832.6 CBY19094.1 - 0.0055 16.8 2.0 0.0055 16.8 2.0 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-RING-like PF08746.11 CBY19094.1 - 0.038 14.3 2.1 0.038 14.3 2.1 2.1 2 0 0 2 2 2 0 RING-like domain Zf_RING PF16744.5 CBY19094.1 - 1.7 8.8 9.7 0.096 12.8 3.3 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger zf-Nse PF11789.8 CBY19094.1 - 2.1 8.2 9.8 0.082 12.7 3.7 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CBY19094.1 - 5 7.4 11.3 19 5.5 7.8 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CBY19094.1 - 9.6 6.1 12.8 0.089 12.6 3.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Tim10_DDP PF02953.15 CBY19095.1 - 8.4e-11 41.4 2.2 1.2e-10 40.9 2.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ATP-synt_ab_C PF00306.27 CBY19095.1 - 0.022 15.1 0.1 0.03 14.6 0.1 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain FlgT_M PF16539.5 CBY19095.1 - 0.057 13.6 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain CRIM PF16978.5 CBY19096.1 - 0.00013 22.1 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain TOH_N PF12549.8 CBY19096.1 - 0.043 13.7 0.6 0.11 12.4 0.6 1.6 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal TatD_DNase PF01026.21 CBY19097.1 - 2.1e-50 171.5 0.0 2.6e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CBY19097.1 - 0.012 15.4 0.4 0.068 12.9 0.0 2.1 2 1 0 2 2 2 0 Amidohydrolase Amidohydro_1 PF01979.20 CBY19097.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase family Pro_isomerase PF00160.21 CBY19098.1 - 5.1e-45 153.6 0.0 5.8e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HA2 PF04408.23 CBY19099.1 - 8.5e-21 74.3 0.2 1.7e-20 73.3 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBY19099.1 - 1.1e-20 73.7 0.1 5.9e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBY19099.1 - 5.7e-12 46.0 0.0 1.2e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY19099.1 - 1.2e-06 28.4 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBY19099.1 - 8.5e-05 22.9 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CBY19099.1 - 0.0017 18.9 0.2 0.22 12.0 0.2 2.5 1 1 0 1 1 1 1 ABC transporter SRP54 PF00448.22 CBY19099.1 - 0.0021 17.7 0.1 0.01 15.4 0.1 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CBY19099.1 - 0.0023 18.2 1.1 0.0089 16.3 0.3 2.4 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 CBY19099.1 - 0.0051 16.8 0.0 3.9 7.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CBY19099.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY19099.1 - 0.029 14.1 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY19099.1 - 0.054 13.0 0.0 0.18 11.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 CBY19099.1 - 0.071 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SSE PF00437.20 CBY19099.1 - 0.077 12.0 0.0 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 CBY19099.1 - 0.098 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 CBY19099.1 - 0.17 11.6 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 CBY19099.1 - 0.17 11.9 0.0 0.49 10.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 CBY19099.1 - 0.24 11.9 0.0 0.56 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M14 PF00246.24 CBY19100.1 - 4e-06 26.8 0.2 9e-05 22.4 0.2 2.7 2 1 0 2 2 2 1 Zinc carboxypeptidase DUF3361 PF11841.8 CBY19101.1 - 0.0051 16.8 1.4 0.63 10.0 0.4 3.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3361) SUI1 PF01253.22 CBY19102.1 - 1.3e-25 89.7 0.7 1.7e-25 89.3 0.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 PRKCSH-like PF12999.7 CBY19103.1 - 1.8e-38 132.1 6.0 1.8e-38 132.1 6.0 3.3 2 2 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CBY19103.1 - 3.4e-31 108.0 0.1 3.4e-31 108.0 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CBY19103.1 - 4e-05 24.5 2.0 0.00021 22.2 1.8 2.3 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 CBY19103.1 - 0.15 12.3 16.4 0.6 10.4 4.7 2.9 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A DUF948 PF06103.11 CBY19103.1 - 0.61 10.4 6.9 1.1 9.5 0.8 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 CBY19103.1 - 0.72 9.4 8.4 0.073 12.6 3.7 1.7 2 0 0 2 2 2 0 fzo-like conserved region P53 PF00870.18 CBY19104.1 - 7.1e-06 25.9 0.1 1.3e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 P53 DNA-binding domain CEP1-DNA_bind PF09287.10 CBY19104.1 - 0.0049 16.5 0.1 0.0074 16.0 0.1 1.3 1 0 0 1 1 1 1 CEP-1, DNA binding RAI1 PF08652.11 CBY19105.1 - 2.5e-21 75.6 0.2 9.6e-21 73.8 0.1 2.1 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease EMP24_GP25L PF01105.24 CBY19106.1 - 4.7 7.1 8.2 2.3 8.2 0.0 3.7 4 0 0 4 4 4 0 emp24/gp25L/p24 family/GOLD zf-C2H2 PF00096.26 CBY19108.1 - 4.9e-13 48.7 49.7 0.0067 16.8 2.4 8.9 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY19108.1 - 5.2e-10 39.3 6.2 5.8e-06 26.5 0.7 7.4 9 0 0 9 9 9 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY19108.1 - 6.4e-06 26.6 51.1 0.09 13.7 0.4 8.6 8 1 0 8 8 8 6 C2H2-type zinc finger zf-met PF12874.7 CBY19108.1 - 0.0054 17.1 23.3 0.22 12.0 0.2 6.8 6 0 0 6 6 6 2 Zinc-finger of C2H2 type DNA_RNApol_7kD PF03604.13 CBY19108.1 - 0.88 9.3 4.9 15 5.4 0.1 3.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit FOXP-CC PF16159.5 CBY19108.1 - 3.2 8.4 19.3 16 6.3 0.1 5.7 4 3 2 6 6 6 0 FOXP coiled-coil domain Mito_carr PF00153.27 CBY19109.1 - 1e-36 124.7 3.0 8.6e-16 57.7 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MccV PF17508.2 CBY19109.1 - 3.3 8.3 5.9 1.5 9.4 0.4 2.9 2 1 1 3 3 3 0 Microcin V bacteriocin UAA PF08449.11 CBY19110.1 - 2.1e-39 135.5 24.3 2.5e-39 135.3 24.3 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBY19110.1 - 2.5e-12 46.8 21.7 5e-12 45.8 21.7 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY19110.1 - 6.8e-11 42.5 35.5 8e-06 26.1 14.4 2.7 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 CBY19110.1 - 5.7e-07 29.1 23.3 8.5e-07 28.5 23.3 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 CBY19110.1 - 1.5e-06 27.7 14.5 1.5e-06 27.7 14.5 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter CRT-like PF08627.10 CBY19110.1 - 0.00047 19.2 28.0 0.00074 18.6 7.3 2.1 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like DUF3479 PF11965.8 CBY19110.1 - 0.031 14.4 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) RIH_assoc PF08454.11 CBY19110.1 - 0.13 12.2 2.0 0.36 10.7 2.0 1.8 1 1 0 1 1 1 0 RyR and IP3R Homology associated GAPES4 PF17157.4 CBY19110.1 - 0.19 12.2 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain TMEM234 PF10639.9 CBY19110.1 - 8.4 6.5 18.4 4.2 7.4 4.5 3.1 2 2 1 3 3 3 0 Putative transmembrane family 234 Mito_carr PF00153.27 CBY19112.1 - 4e-20 71.6 2.5 9.2e-16 57.6 0.3 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein PMM PF03332.13 CBY19113.1 - 5.4e-94 314.1 1.8 6.2e-94 313.9 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CBY19113.1 - 1.3e-09 38.2 0.1 7.8e-09 35.6 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBY19113.1 - 0.012 15.7 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY19113.1 - 0.11 12.8 0.0 0.41 10.9 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RVT_1 PF00078.27 CBY19114.1 - 1.7e-11 44.1 0.0 8e-09 35.3 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) LAP1C PF05609.12 CBY19116.1 - 3.6 6.6 26.0 4.1 6.4 26.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Phospholip_A2_1 PF00068.19 CBY19117.1 - 0.0011 19.4 7.3 0.0011 19.4 7.3 2.4 2 2 0 2 2 2 1 Phospholipase A2 TPR_2 PF07719.17 CBY19118.1 - 2.1e-18 64.9 10.8 0.00031 20.6 0.1 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY19118.1 - 1.1e-15 56.6 8.7 0.00072 19.3 0.0 5.9 7 1 1 8 8 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBY19118.1 - 1.1e-13 51.4 2.0 1.3e-06 28.8 2.4 4.4 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBY19118.1 - 7.8e-12 44.4 6.7 0.0033 17.5 0.4 5.7 7 0 0 7 7 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY19118.1 - 2.1e-11 43.9 2.4 1.2e-05 25.5 0.0 4.1 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CBY19118.1 - 3.4e-11 43.1 0.2 0.016 15.3 0.0 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY19118.1 - 8.3e-11 41.8 2.4 0.014 16.2 0.1 6.0 2 1 5 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBY19118.1 - 8.8e-10 39.1 5.1 0.00082 20.0 0.8 4.4 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY19118.1 - 6.4e-09 36.0 5.2 0.00011 22.4 0.0 4.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBY19118.1 - 1.3e-07 31.2 7.5 0.00042 19.9 0.3 4.2 2 2 2 4 4 4 2 TPR repeat TPR_17 PF13431.6 CBY19118.1 - 4.5e-07 29.8 5.0 0.22 12.0 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 CBY19118.1 - 1.7e-06 27.9 0.3 0.031 14.0 0.7 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain NARP1 PF12569.8 CBY19118.1 - 4.8e-06 25.8 0.0 0.0018 17.2 0.0 2.4 1 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CBY19118.1 - 0.00012 22.5 4.5 3.3 8.5 0.1 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY19118.1 - 0.00019 21.2 1.4 5.8 7.2 0.2 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBY19118.1 - 0.0014 17.9 0.6 0.0073 15.6 0.7 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY19118.1 - 0.0023 17.8 0.0 20 5.2 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBY19118.1 - 0.0057 16.1 1.3 0.81 9.2 0.1 2.8 2 0 0 2 2 2 1 SHNi-TPR TPR_4 PF07721.14 CBY19118.1 - 0.016 15.7 0.0 11 7.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY19118.1 - 0.025 14.0 0.8 0.08 12.3 0.5 1.9 1 1 1 2 2 2 0 MalT-like TPR region Coatomer_E PF04733.14 CBY19118.1 - 0.033 13.6 0.2 2 7.8 0.0 3.1 3 0 0 3 3 3 0 Coatomer epsilon subunit RPN7 PF10602.9 CBY19118.1 - 0.07 12.8 0.1 2.2 8.0 0.0 2.9 2 1 0 2 2 2 0 26S proteasome subunit RPN7 YccV-like PF08755.11 CBY19119.1 - 3.9e-21 75.4 0.2 1.6e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like RPA43_OB PF17875.1 CBY19119.1 - 0.054 14.1 0.5 0.09 13.4 0.5 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Chromo PF00385.24 CBY19120.1 - 8.7e-16 57.6 0.1 1.3e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DnaJ PF00226.31 CBY19121.1 - 0.0015 18.6 0.1 0.0043 17.2 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain TFIID_20kDa PF03847.13 CBY19122.1 - 4.8e-21 75.0 0.2 7.3e-21 74.4 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 CBY19122.1 - 0.00043 20.6 0.0 0.00081 19.8 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY19122.1 - 0.002 18.4 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBY19122.1 - 0.0028 17.7 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CBY19122.1 - 0.0062 16.6 0.1 0.016 15.3 0.0 1.7 2 1 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit PUF PF00806.19 CBY19123.1 - 1.4e-66 216.5 12.7 5.5e-09 35.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CBY19123.1 - 0.023 15.0 0.3 7.5 6.9 0.1 3.9 2 1 1 4 4 4 0 CPL (NUC119) domain Importin_rep_3 PF18806.1 CBY19123.1 - 0.07 13.2 0.1 0.57 10.3 0.0 2.5 1 1 1 2 2 2 0 Importin 13 repeat Ku_PK_bind PF08785.11 CBY19123.1 - 0.17 12.0 1.2 10 6.3 0.0 3.4 3 0 0 3 3 3 0 Ku C terminal domain like TBPIP PF07106.13 CBY19123.1 - 5.7 7.0 6.5 7.8 6.5 0.2 4.2 4 2 1 5 5 5 0 TBPIP/Hop2 winged helix domain UPF0160 PF03690.13 CBY19124.1 - 5.3e-133 443.5 0.0 5.9e-133 443.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ras PF00071.22 CBY19125.1 - 1e-63 213.7 0.3 1.3e-63 213.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY19125.1 - 2.1e-35 121.6 0.1 3.2e-35 121.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY19125.1 - 1.1e-19 70.6 0.1 1.4e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY19125.1 - 3.9e-06 26.4 0.0 5.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY19125.1 - 5.4e-06 26.1 0.1 1.6e-05 24.6 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBY19125.1 - 3e-05 23.5 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY19125.1 - 0.00021 21.4 0.1 0.00032 20.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY19125.1 - 0.0012 18.8 0.2 0.75 9.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 CBY19125.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 CBY19125.1 - 0.019 15.4 0.0 0.035 14.5 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 CBY19125.1 - 0.026 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 CBY19125.1 - 0.052 13.8 0.1 0.27 11.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain MCM PF00493.23 CBY19125.1 - 0.054 12.6 0.0 2.2 7.3 0.0 2.5 1 1 1 3 3 3 0 MCM P-loop domain AAA_24 PF13479.6 CBY19125.1 - 0.058 13.1 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CBY19125.1 - 0.071 13.1 0.1 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY19125.1 - 0.079 13.3 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CBY19125.1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain Porin_3 PF01459.22 CBY19126.1 - 2.9e-10 40.1 3.2 6.5e-10 38.9 3.2 1.5 1 1 0 1 1 1 1 Eukaryotic porin Adaptin_N PF01602.20 CBY19128.1 - 3e-115 385.8 1.2 4e-115 385.4 1.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBY19128.1 - 8.5e-21 74.7 1.3 6.4e-15 55.6 0.1 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY19128.1 - 1.6e-08 34.8 3.4 0.015 15.7 0.1 4.8 2 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 CBY19128.1 - 0.0011 19.1 0.2 0.89 10.0 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat Asp-B-Hydro_N PF05279.11 CBY19128.1 - 0.16 12.0 7.4 0.28 11.2 7.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pns11_12 PF17464.2 CBY19128.1 - 3.2 7.4 12.8 6.3 6.5 12.8 1.4 1 0 0 1 1 1 0 Non-structural protein 11 and 12 PDZ PF00595.24 CBY19129.1 - 1e-98 323.8 15.6 3.2e-13 49.8 0.1 9.3 9 0 0 9 9 9 9 PDZ domain PDZ_6 PF17820.1 CBY19129.1 - 8.9e-87 284.8 12.7 4.8e-12 45.5 0.0 9.4 9 0 0 9 9 9 9 PDZ domain PDZ_2 PF13180.6 CBY19129.1 - 1.4e-63 211.1 10.7 1.3e-07 31.8 0.0 9.4 8 1 1 9 9 9 9 PDZ domain DUF3394 PF11874.8 CBY19129.1 - 4.2e-10 39.6 0.4 0.099 12.3 0.1 6.8 5 2 2 7 7 7 3 Domain of unknown function (DUF3394) Tetraspanin PF00335.20 CBY19129.1 - 4.5e-07 29.8 0.3 8.4e-07 28.9 0.3 1.4 1 0 0 1 1 1 1 Tetraspanin family PDZ_4 PF17816.1 CBY19129.1 - 1.6e-05 25.3 11.6 0.74 10.2 0.0 7.1 8 0 0 8 8 8 2 PDZ domain EMP24_GP25L PF01105.24 CBY19131.1 - 7.5e-50 169.4 0.5 8.6e-50 169.2 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TRPM_tetra PF16519.5 CBY19131.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Zn-C2H2_12 PF18112.1 CBY19132.1 - 4.7e-12 46.1 5.2 1.3e-11 44.7 5.2 1.8 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 CBY19132.1 - 0.15 12.4 0.8 0.31 11.3 0.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding EVI2A PF05399.11 CBY19132.1 - 4.1 6.9 8.8 1.1 8.7 5.5 1.7 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) zf-C2H2_4 PF13894.6 CBY19133.1 - 2.8e-08 33.9 37.1 0.075 13.9 1.3 6.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY19133.1 - 7e-05 23.1 32.5 0.083 13.4 0.5 6.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type fn3 PF00041.21 CBY19133.1 - 0.002 18.4 0.0 0.0057 17.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain zf-C2H2_8 PF15909.5 CBY19133.1 - 0.07 13.4 14.0 0.58 10.5 5.3 3.7 2 1 0 3 3 3 0 C2H2-type zinc ribbon Evr1_Alr PF04777.13 CBY19133.1 - 4.9 7.7 6.8 71 4.0 0.4 4.1 3 0 0 3 3 3 0 Erv1 / Alr family PAS_6 PF08348.11 CBY19135.1 - 0.075 12.9 0.7 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 YheO-like PAS domain Adaptin_binding PF10199.9 CBY19135.1 - 1.8 9.2 5.2 10 6.8 3.7 2.6 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 PDEase_I PF00233.19 CBY19136.1 - 9.2e-14 51.7 0.0 1.6e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TPR_2 PF07719.17 CBY19137.1 - 2.6e-07 30.2 0.0 0.089 13.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY19137.1 - 5.5e-06 26.4 0.3 0.0015 18.6 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY19137.1 - 5.8e-06 26.5 0.5 0.0002 21.6 0.5 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY19137.1 - 0.0041 16.9 0.6 0.077 12.8 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY19137.1 - 0.014 15.4 0.1 4 7.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY19137.1 - 0.027 14.7 0.2 2 8.8 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat FKBP_C PF00254.28 CBY19137.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase MIT PF04212.18 CBY19137.1 - 0.084 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 CBY19137.1 - 0.18 12.5 0.1 7.1 7.4 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Casc1_N PF15927.5 CBY19138.1 - 1.4e-32 113.0 16.2 1.4e-32 113.0 16.2 2.6 3 0 0 3 3 3 1 Cancer susceptibility candidate 1 N-terminus PrmA PF06325.13 CBY19138.1 - 0.0073 15.7 0.4 0.019 14.4 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CC2D2AN-C2 PF15625.6 CBY19140.1 - 8.7e-15 54.9 0.2 1.7e-14 53.9 0.1 1.6 1 1 1 2 2 2 1 CC2D2A N-terminal C2 domain AAA_22 PF13401.6 CBY19141.1 - 1.1e-14 54.8 0.0 5e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY19141.1 - 8.7e-13 49.0 0.2 1.7e-10 41.5 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CBY19141.1 - 1.2e-12 48.4 0.0 3.2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CBY19141.1 - 4.1e-05 23.9 0.6 0.00024 21.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBY19141.1 - 4.9e-05 22.9 0.1 9.7e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 CBY19141.1 - 0.00023 20.9 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBY19141.1 - 0.00034 20.6 0.0 0.00087 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBY19141.1 - 0.0011 18.3 0.0 0.0029 16.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin DUF2075 PF09848.9 CBY19141.1 - 0.002 17.4 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 CBY19141.1 - 0.002 17.9 0.5 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 CBY19141.1 - 0.003 17.6 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA lid domain Rad17 PF03215.15 CBY19141.1 - 0.0031 17.5 0.1 0.0076 16.2 0.1 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain TIP49 PF06068.13 CBY19141.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Cdc6_C PF09079.11 CBY19141.1 - 0.013 15.5 0.0 0.043 13.8 0.1 1.9 2 0 0 2 2 1 0 CDC6, C terminal winged helix domain PIF1 PF05970.14 CBY19141.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Viral_helicase1 PF01443.18 CBY19141.1 - 0.015 15.1 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CBY19141.1 - 0.015 15.7 0.1 0.062 13.7 0.1 2.2 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 CBY19141.1 - 0.016 15.1 0.3 0.05 13.5 0.3 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Helicase_RecD PF05127.14 CBY19141.1 - 0.02 14.7 0.0 0.085 12.7 0.0 2.0 2 0 0 2 2 2 0 Helicase AAA_11 PF13086.6 CBY19141.1 - 0.022 14.6 0.1 0.057 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CBY19141.1 - 0.031 14.3 1.1 0.099 12.6 0.1 2.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_17 PF13207.6 CBY19141.1 - 0.035 14.5 0.3 0.21 12.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain GvpD PF07088.11 CBY19141.1 - 0.044 12.4 0.0 0.071 11.7 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein DUF815 PF05673.13 CBY19141.1 - 0.06 12.5 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AIG1 PF04548.16 CBY19141.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_5 PF07728.14 CBY19141.1 - 0.073 13.1 0.1 1 9.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 CBY19141.1 - 0.082 13.3 0.1 0.26 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA C-terminal domain DEAD PF00270.29 CBY19141.1 - 0.087 12.6 0.9 1.4 8.7 0.1 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase C2 PF00168.30 CBY19142.1 - 1.9e-05 24.9 0.0 4.3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 C2 domain Transmemb_17 PF09799.9 CBY19143.1 - 5.9e-24 84.7 7.1 6.8e-24 84.5 7.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein Babuvirus_MP PF07234.11 CBY19143.1 - 0.41 10.8 7.9 0.56 10.4 0.4 2.1 2 0 0 2 2 2 0 Movement and RNA silencing protein Transmemb_17 PF09799.9 CBY19144.1 - 1.3e-16 61.1 10.9 1.6e-16 60.8 10.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein HEAT_2 PF13646.6 CBY19145.1 - 0.00029 21.2 1.0 0.086 13.2 0.1 3.7 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 CBY19145.1 - 0.0016 18.5 7.0 3.2 8.3 0.1 5.0 5 0 0 5 5 5 2 HEAT repeat RTTN_N PF14726.6 CBY19145.1 - 0.0025 18.6 4.3 0.83 10.5 0.4 4.3 4 1 0 4 4 4 1 Rotatin, an armadillo repeat protein, centriole functioning 7TMR-HDED PF07697.11 CBY19145.1 - 0.02 15.0 1.2 1.3 9.1 0.0 3.0 2 1 0 2 2 2 0 7TM-HD extracellular CtsR_C PF17727.1 CBY19145.1 - 0.058 13.5 0.6 0.28 11.4 0.2 2.5 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain Sec7_N PF12783.7 CBY19145.1 - 3.3 7.6 14.9 0.25 11.2 0.1 4.8 3 2 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal BPL_LplA_LipB PF03099.19 CBY19146.1 - 1.4e-07 31.5 0.0 3.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CtsR_C PF17727.1 CBY19146.1 - 0.032 14.3 0.2 0.076 13.2 0.2 1.6 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain BPL_LplA_LipB PF03099.19 CBY19147.1 - 1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family EMP24_GP25L PF01105.24 CBY19148.1 - 2.5e-38 131.8 0.2 2.9e-38 131.6 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UDPG_MGDP_dh_N PF03721.14 CBY19148.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DNA_photolyase PF00875.18 CBY19149.1 - 2.8e-25 89.2 0.0 3.3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 CBY19150.1 - 1.9e-63 213.6 0.7 2.4e-63 213.3 0.7 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Palm_thioest PF02089.15 CBY19151.1 - 8.9e-84 281.1 0.1 1e-83 280.9 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CBY19151.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CBY19151.1 - 0.21 11.3 3.9 12 5.6 0.1 3.0 1 1 2 3 3 3 0 Phospholipase/Carboxylesterase muHD PF10291.9 CBY19152.1 - 1.1e-06 28.3 0.1 3.2e-06 26.8 0.1 1.7 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CBY19152.1 - 1.8e-05 25.0 0.1 6.1e-05 23.2 0.1 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DegS PF05384.11 CBY19152.1 - 0.056 12.9 3.3 0.082 12.4 0.4 2.3 1 1 0 2 2 2 0 Sensor protein DegS RRM_1 PF00076.22 CBY19153.1 - 2e-19 69.2 0.0 2.9e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY19153.1 - 0.0091 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nab6_mRNP_bdg PF10567.9 CBY19153.1 - 0.027 14.0 4.4 0.072 12.6 0.0 2.3 2 1 0 2 2 2 0 RNA-recognition motif DTW PF03942.15 CBY19154.1 - 2.2e-27 96.0 0.0 3.3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 DTW domain RE_EcoO109I PF14511.6 CBY19154.1 - 0.11 12.1 0.0 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 Type II restriction endonuclease EcoO109I YfzA PF14118.6 CBY19155.1 - 0.053 13.9 0.2 0.091 13.2 0.2 1.4 1 0 0 1 1 1 0 YfzA-like protein DnaT PF17948.1 CBY19155.1 - 0.072 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 DnaT DNA-binding domain Pkinase PF00069.25 CBY19156.1 - 8.4e-09 35.2 0.1 0.00065 19.1 0.1 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19156.1 - 7.1e-06 25.5 1.9 0.0036 16.6 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Syntaxin PF00804.25 CBY19158.1 - 3.8 7.1 13.4 1.5 8.5 9.3 2.1 1 1 0 2 2 2 0 Syntaxin UQ_con PF00179.26 CBY19159.1 - 1.9e-47 160.4 0.0 2.1e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY19159.1 - 2.5e-06 27.2 0.0 3.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B DEAD PF00270.29 CBY19160.1 - 2.1e-42 144.9 0.0 3.2e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY19160.1 - 2.1e-28 98.9 0.4 1.4e-27 96.2 0.5 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY19160.1 - 0.00025 21.1 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBY19160.1 - 0.02 14.2 0.2 0.039 13.3 0.2 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 CBY19160.1 - 0.031 13.5 0.1 0.046 12.9 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Sulfotransfer_1 PF00685.27 CBY19161.1 - 2.3e-17 63.3 0.0 3.4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY19161.1 - 7.6e-14 52.6 0.0 2.3e-06 28.2 0.0 3.1 1 1 2 3 3 3 3 Sulfotransferase family WD40 PF00400.32 CBY19162.1 - 1.4e-11 44.7 1.8 0.07 14.0 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY19162.1 - 5.7e-10 39.4 0.0 0.0031 17.8 0.0 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CBY19162.1 - 0.086 13.4 0.0 0.59 10.7 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain Frtz PF11768.8 CBY19162.1 - 0.14 10.4 0.0 1.2 7.3 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 CBY19162.1 - 0.18 11.8 1.1 47 4.2 0.1 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat Cytochrom_B561 PF03188.16 CBY19164.1 - 0.029 14.5 0.6 0.029 14.5 0.6 2.1 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 G_glu_transpept PF01019.21 CBY19165.1 - 5.4e-130 434.6 0.0 6.8e-130 434.2 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SGL PF08450.12 CBY19165.1 - 3.5e-32 111.9 0.1 6.1e-32 111.1 0.1 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 CBY19165.1 - 0.0038 17.2 1.0 7.8 6.7 0.0 4.1 3 0 0 3 3 3 1 NHL repeat Str_synth PF03088.16 CBY19165.1 - 0.0039 17.3 0.0 0.16 12.1 0.0 2.9 2 1 0 2 2 2 1 Strictosidine synthase Oxidored_q2 PF00420.24 CBY19166.1 - 0.036 13.7 0.1 0.05 13.2 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L EST1_DNA_bind PF10373.9 CBY19168.1 - 6.6e-30 104.6 3.8 6.6e-30 104.6 3.8 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CBY19168.1 - 1.9e-14 54.5 0.5 6.5e-14 52.7 0.5 2.0 1 0 0 1 1 1 1 Telomerase activating protein Est1 YscK PF06578.12 CBY19168.1 - 0.0055 16.2 0.2 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 YOP proteins translocation protein K (YscK) zf-RING_2 PF13639.6 CBY19169.1 - 1.7e-05 25.1 13.1 1.7e-05 25.1 13.1 2.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY19169.1 - 8.4e-05 22.4 10.6 8.4e-05 22.4 10.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY19169.1 - 0.00088 19.1 13.2 0.00088 19.1 13.2 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) HERV-K_env_2 PF13804.6 CBY19169.1 - 0.025 14.4 0.5 0.04 13.7 0.5 1.4 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein DUF3231 PF11553.8 CBY19169.1 - 0.048 13.3 1.8 0.074 12.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) UPF0242 PF06785.11 CBY19169.1 - 0.16 12.1 6.3 0.25 11.4 6.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 CBY19169.1 - 0.34 10.1 7.1 0.55 9.4 7.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein EcsC PF12787.7 CBY19169.1 - 0.85 9.2 3.3 0.46 10.1 0.5 1.8 1 1 1 2 2 2 0 EcsC protein family zf-C3HC4 PF00097.25 CBY19169.1 - 1.4 8.8 16.3 1.2 9.0 12.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LMBR1 PF04791.16 CBY19169.1 - 2.8 6.8 5.1 4 6.2 5.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein WAPL PF07814.13 CBY19170.1 - 0.0014 17.5 0.1 0.0024 16.7 0.1 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin LRR_8 PF13855.6 CBY19171.1 - 3.9e-31 106.6 34.1 6e-12 45.2 0.3 6.3 2 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 CBY19171.1 - 2.8e-25 88.0 26.6 0.00013 22.3 3.9 6.2 3 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRRNT PF01462.18 CBY19171.1 - 4e-09 35.9 1.5 4.9e-08 32.4 1.2 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 CBY19171.1 - 1.2e-05 25.0 8.4 0.0016 18.0 0.4 3.6 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 CBY19171.1 - 7.4e-05 22.8 30.3 2.5 9.0 0.2 8.6 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.6 CBY19171.1 - 0.00018 21.3 21.8 2.8 8.2 1.2 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_2 PF07723.13 CBY19171.1 - 0.0018 18.9 7.5 0.22 12.3 0.1 5.7 5 2 0 5 5 5 1 Leucine Rich Repeat LRR_5 PF13306.6 CBY19171.1 - 0.0079 16.1 0.0 1.8 8.5 0.0 2.8 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 CBY19171.1 - 1.6 9.0 7.2 0.44 10.8 0.4 3.4 4 0 0 4 4 4 0 FNIP Repeat Mur_ligase_M PF08245.12 CBY19172.1 - 4e-08 33.5 0.0 7.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Mur ligase middle domain ATP13 PF12921.7 CBY19172.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase expression zf-LSD1 PF06943.12 CBY19172.1 - 1 9.3 5.7 0.5 10.3 2.2 2.2 2 0 0 2 2 2 0 LSD1 zinc finger META PF03724.16 CBY19173.1 - 0.39 10.7 1.8 2.4 8.1 0.0 2.6 3 0 0 3 3 3 0 META domain EGF_CA PF07645.15 CBY19176.1 - 1.9e-07 31.2 20.1 3.4e-07 30.3 9.4 3.0 2 1 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.7 CBY19176.1 - 0.00043 20.4 4.8 0.00043 20.4 4.8 2.2 2 0 0 2 2 2 1 EGF domain CBM_2 PF00553.19 CBY19176.1 - 0.00094 19.4 8.8 0.0092 16.3 0.1 3.2 2 1 1 3 3 3 2 Cellulose binding domain cEGF PF12662.7 CBY19176.1 - 0.0027 17.6 11.1 0.01 15.8 3.4 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like Bromo_TP PF07524.13 CBY19177.1 - 1.1e-05 25.3 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Lactamase_B PF00753.27 CBY19178.1 - 2.9e-06 27.4 5.5 3e-05 24.1 5.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 CBY19178.1 - 4.2e-06 27.2 0.1 7.5e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 CBY19178.1 - 0.059 12.9 1.8 0.067 12.7 0.7 1.8 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Mur_ligase_M PF08245.12 CBY19181.1 - 3.1e-17 63.2 0.0 1.8e-07 31.4 0.0 2.8 2 1 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 CBY19181.1 - 0.0024 18.1 0.0 0.19 12.0 0.0 2.9 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain S4 PF01479.25 CBY19181.1 - 0.082 12.6 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 S4 domain DUF1125 PF06563.11 CBY19181.1 - 0.099 12.6 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1125) UBA_6 PF18039.1 CBY19181.1 - 0.11 12.5 0.0 21 5.1 0.0 2.6 2 0 0 2 2 2 0 UBA-like domain DUF3630 PF12305.8 CBY19181.1 - 0.12 12.4 0.0 24 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3630) PSI_PsaE PF02427.17 CBY19181.1 - 0.17 11.6 0.0 14 5.4 0.0 2.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE Rbsn PF11464.8 CBY19181.1 - 0.18 11.5 4.6 3.8 7.3 0.5 2.8 2 0 0 2 2 2 0 Rabenosyn Rab binding domain zf-LSD1 PF06943.12 CBY19181.1 - 0.27 11.1 16.2 0.99 9.3 2.2 3.2 3 0 0 3 3 3 0 LSD1 zinc finger SMG1 PF15785.5 CBY19182.1 - 2e-75 254.5 0.1 6.3e-75 252.8 0.1 1.8 1 0 0 1 1 1 1 Serine/threonine-protein kinase smg-1 PI3_PI4_kinase PF00454.27 CBY19182.1 - 6.5e-47 160.5 0.6 2.7e-46 158.4 0.0 2.5 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CBY19182.1 - 1.1e-07 31.6 0.0 3.7e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CBY19182.1 - 0.087 13.1 0.0 0.66 10.4 0.0 2.6 1 0 0 1 1 1 0 HEAT repeat HTH_40 PF14493.6 CBY19182.1 - 0.22 12.0 1.1 38 4.8 0.0 3.3 2 0 0 2 2 2 0 Helix-turn-helix domain FRB_dom PF08771.11 CBY19182.1 - 3.1 8.3 11.8 0.091 13.2 0.4 4.2 3 1 1 4 4 4 0 FKBP12-rapamycin binding domain Ins_P5_2-kin PF06090.12 CBY19183.1 - 9.1e-43 146.9 0.1 1.1e-42 146.7 0.1 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase PLDc PF00614.22 CBY19184.1 - 1.1e-15 57.1 0.1 1.9e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CBY19184.1 - 1.2e-13 51.1 0.4 1.5e-07 31.4 0.2 2.9 2 1 0 2 2 2 2 PLD-like domain PH PF00169.29 CBY19184.1 - 1.7e-06 28.5 2.2 5.7e-05 23.6 2.2 3.0 1 1 0 1 1 1 1 PH domain Glyco_hydro_6 PF01341.17 CBY19184.1 - 0.014 15.2 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 PH_11 PF15413.6 CBY19184.1 - 0.027 14.9 0.4 0.027 14.9 0.4 4.0 4 1 1 5 5 5 0 Pleckstrin homology domain DUF4823 PF16105.5 CBY19184.1 - 0.11 12.4 1.5 1.4 8.8 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4823) Band_7 PF01145.25 CBY19185.1 - 1.3e-28 100.3 1.7 1.6e-28 99.9 1.7 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY19185.1 - 0.052 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family LRR_8 PF13855.6 CBY19186.1 - 6.7e-10 38.6 8.9 5.8e-06 26.0 0.9 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY19186.1 - 5.3e-08 33.0 11.9 2.7e-05 24.4 1.3 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY19186.1 - 0.11 13.1 10.8 19 6.3 0.1 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat GOLD_2 PF13897.6 CBY19186.1 - 2.1 8.9 3.6 7.5 7.1 1.1 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking EGF_CA PF07645.15 CBY19188.1 - 9.6e-85 278.6 327.2 4.3e-10 39.6 10.6 19.1 18 1 1 19 19 19 18 Calcium-binding EGF domain EGF_3 PF12947.7 CBY19188.1 - 1.8e-41 140.0 312.9 7.7e-09 35.6 10.1 19.3 18 0 0 18 18 18 18 EGF domain cEGF PF12662.7 CBY19188.1 - 6.7e-35 118.6 195.7 3.9e-05 23.5 3.0 20.3 19 0 0 19 19 19 15 Complement Clr-like EGF-like EGF PF00008.27 CBY19188.1 - 1.5e-09 37.9 264.6 0.00057 20.1 6.2 20.0 18 1 0 18 18 18 11 EGF-like domain hEGF PF12661.7 CBY19188.1 - 2.5e-06 27.9 211.8 0.015 15.9 1.0 22.1 20 1 0 20 20 20 13 Human growth factor-like EGF SNF PF00209.18 CBY19189.1 - 7.1e-188 625.5 30.0 8.1e-188 625.3 30.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Phospholip_A2_1 PF00068.19 CBY19190.1 - 3.6e-12 46.7 5.0 5.2e-12 46.2 5.0 1.2 1 0 0 1 1 1 1 Phospholipase A2 Fcf1 PF04900.12 CBY19190.1 - 0.056 13.8 0.1 0.098 13.1 0.1 1.3 1 0 0 1 1 1 0 Fcf1 Trypsin PF00089.26 CBY19191.1 - 3.3e-37 128.4 0.6 7.1e-28 97.9 0.0 2.0 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CBY19191.1 - 2.9e-05 25.0 0.0 4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S24 PF00717.23 CBY19191.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase S24-like zf-3CxxC_2 PF17180.4 CBY19192.1 - 5.6e-23 81.4 13.8 5.6e-23 81.4 13.8 3.6 2 2 1 3 3 3 1 Zinc-binding domain 7tm_2 PF00002.24 CBY19193.1 - 2.7e-16 59.6 10.6 1e-15 57.7 10.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) TMEM138 PF14935.6 CBY19193.1 - 0.09 13.4 4.6 0.65 10.7 0.5 2.8 3 0 0 3 3 3 0 Transmembrane protein 138 DUF4516 PF14990.6 CBY19193.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) DUF2207 PF09972.9 CBY19193.1 - 9.9 4.8 10.2 1.5 7.5 1.1 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Homeodomain PF00046.29 CBY19194.1 - 1.8e-19 69.3 1.1 1.8e-19 69.3 1.1 1.6 2 0 0 2 2 2 1 Homeodomain LIM PF00412.22 CBY19194.1 - 9.5e-09 35.4 29.7 2e-05 24.7 17.2 2.4 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.11 CBY19194.1 - 1.1e-05 25.3 0.1 9e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain DUF3123 PF11321.8 CBY19194.1 - 0.0084 16.8 0.0 0.025 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3123) HLH PF00010.26 CBY19195.1 - 1e-06 28.6 2.2 1.5e-06 28.1 2.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Connexin PF00029.19 CBY19196.1 - 1.3e-23 84.0 2.0 1.3e-23 84.0 2.0 1.9 2 0 0 2 2 2 1 Connexin DUF4611 PF15387.6 CBY19196.1 - 0.0062 16.7 2.1 0.011 15.9 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Ank_2 PF12796.7 CBY19197.1 - 0.00029 21.4 0.0 0.0014 19.2 0.0 1.9 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY19197.1 - 0.015 15.7 0.0 3 8.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 CBY19197.1 - 0.14 12.8 0.0 42 5.2 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat TTL PF03133.15 CBY19198.1 - 2.1e-86 289.7 0.0 2.1e-86 289.7 0.0 2.9 4 0 0 4 4 4 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY19198.1 - 5.4e-06 25.8 0.0 0.0045 16.3 0.0 2.8 2 0 0 2 2 2 2 YheC/D like ATP-grasp DUF3246 PF11596.8 CBY19198.1 - 0.0017 17.8 0.7 0.0037 16.8 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) ATPgrasp_ST PF14397.6 CBY19198.1 - 0.029 13.6 0.0 0.56 9.4 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Kelch_5 PF13854.6 CBY19199.1 - 2e-20 72.3 0.7 0.00046 20.1 0.0 6.6 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 CBY19199.1 - 4.4e-18 65.1 0.0 4.9e-05 23.5 0.0 5.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY19199.1 - 1.4e-16 60.2 0.5 0.00022 21.1 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY19199.1 - 7.7e-11 41.9 0.1 0.12 12.7 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 CBY19199.1 - 2.5e-09 36.6 3.7 0.0012 18.4 0.0 5.6 6 1 0 6 6 6 2 Kelch motif fn3 PF00041.21 CBY19199.1 - 3.7e-09 36.8 0.9 0.0083 16.4 0.0 4.1 4 0 0 4 4 4 2 Fibronectin type III domain Kelch_2 PF07646.15 CBY19199.1 - 7.3e-09 35.3 3.5 1.1 9.3 0.0 6.2 6 0 0 6 6 6 3 Kelch motif DUF3203 PF11462.8 CBY19199.1 - 0.14 12.4 0.1 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3203) Pur_ac_phosph_N PF16656.5 CBY19199.1 - 0.16 12.5 3.1 3.4 8.3 3.1 2.9 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain ALG11_N PF15924.5 CBY19200.1 - 3e-87 292.1 0.4 5.1e-87 291.3 0.2 1.5 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CBY19200.1 - 1.4e-25 89.8 0.0 2.3e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBY19200.1 - 5.5e-11 43.0 0.0 5.7e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY19200.1 - 0.095 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 HEAT_EZ PF13513.6 CBY19201.1 - 7.9e-19 67.8 3.7 3.3e-08 33.8 0.0 8.7 9 0 0 9 9 9 3 HEAT-like repeat HEAT PF02985.22 CBY19201.1 - 5e-13 48.1 1.4 0.00033 20.7 0.0 8.7 9 0 0 9 9 9 2 HEAT repeat IBN_N PF03810.19 CBY19201.1 - 2.8e-09 36.8 6.7 1.3e-08 34.6 1.6 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain UME PF08064.13 CBY19201.1 - 7e-08 32.3 1.0 0.016 15.1 0.0 5.7 5 1 1 6 6 6 1 UME (NUC010) domain HEAT_2 PF13646.6 CBY19201.1 - 6.4e-06 26.5 4.1 0.017 15.5 0.0 5.7 5 2 0 5 5 5 1 HEAT repeats Arm PF00514.23 CBY19201.1 - 1.2e-05 25.2 4.7 7.1 6.8 0.0 7.2 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CBY19201.1 - 2.6e-05 24.7 4.1 1.7 9.3 0.7 5.7 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CBY19201.1 - 3e-05 24.1 3.3 0.00018 21.6 0.0 3.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CBY19201.1 - 0.00038 20.1 0.7 0.71 9.4 0.0 4.7 3 1 3 6 6 6 2 CLASP N terminal MMS19_C PF12460.8 CBY19201.1 - 0.005 16.0 2.8 15 4.6 0.0 3.5 2 1 0 3 3 3 2 RNAPII transcription regulator C-terminal DUF1349 PF07081.11 CBY19201.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) Phospholip_A2_1 PF00068.19 CBY19202.1 - 5.7e-12 46.1 4.1 5.7e-12 46.1 4.1 1.5 2 0 0 2 2 2 1 Phospholipase A2 HTH_19 PF12844.7 CBY19203.1 - 0.12 12.4 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Kinesin PF00225.23 CBY19204.1 - 2e-75 253.8 0.0 2e-75 253.8 0.0 2.8 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY19204.1 - 1.5e-21 76.9 0.1 6e-19 68.4 0.0 3.2 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 CBY19204.1 - 0.0089 14.9 109.9 0.013 14.4 25.5 5.9 2 2 3 5 5 5 3 Spc7 kinetochore protein ATG16 PF08614.11 CBY19204.1 - 0.0095 16.2 18.0 0.0095 16.2 18.0 6.9 1 1 4 6 6 6 1 Autophagy protein 16 (ATG16) T3SSipB PF16535.5 CBY19204.1 - 0.014 15.9 8.8 0.014 15.9 8.8 6.2 1 1 3 6 6 6 0 Type III cell invasion protein SipB BST2 PF16716.5 CBY19204.1 - 0.018 15.6 3.1 0.018 15.6 3.1 10.0 3 3 6 11 11 11 0 Bone marrow stromal antigen 2 DUF4407 PF14362.6 CBY19204.1 - 0.34 10.2 73.6 2.6 7.3 13.9 5.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) V-SNARE_C PF12352.8 CBY19204.1 - 1.8 8.9 12.7 0.71 10.2 0.6 4.0 4 0 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus DUF3287 PF11690.8 CBY19204.1 - 1.9 8.2 8.7 1.5 8.6 0.7 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3287) TPR_MLP1_2 PF07926.12 CBY19204.1 - 2.1 8.4 111.9 0.13 12.3 2.9 9.2 3 1 5 8 8 7 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 CBY19204.1 - 4.1 7.5 105.3 0.092 12.8 7.5 8.6 2 2 5 9 9 9 0 Afadin- and alpha -actinin-Binding Ion_trans PF00520.31 CBY19205.1 - 7.5e-25 87.6 12.9 1.1e-24 87.0 12.9 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 CBY19205.1 - 1.2e-24 86.2 2.0 2.5e-24 85.2 2.0 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 CBY19205.1 - 5.1e-09 36.6 0.3 0.0047 17.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY19205.1 - 2.6e-06 27.9 0.1 0.035 14.7 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 CBY19205.1 - 5e-06 25.4 9.1 9e-06 24.6 9.1 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ank_3 PF13606.6 CBY19205.1 - 7.2e-06 26.0 0.3 0.68 10.7 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY19205.1 - 0.00044 20.5 0.0 1.1 9.6 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY19205.1 - 0.011 16.2 0.3 1 9.9 0.0 3.4 3 1 0 3 3 3 0 Ankyrin repeat HLH PF00010.26 CBY19206.1 - 2.4e-14 53.0 0.0 3.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VCX_VCY PF15231.6 CBY19206.1 - 0.0025 18.5 1.6 0.0055 17.4 1.6 1.5 1 0 0 1 1 1 1 Variable charge X/Y family Gal-3-0_sulfotr PF06990.11 CBY19207.1 - 7.2e-37 127.2 3.8 9.7e-27 93.9 1.1 3.0 2 1 0 2 2 2 2 Galactose-3-O-sulfotransferase Ist1 PF03398.14 CBY19209.1 - 1.8e-52 177.5 5.9 2.2e-52 177.3 5.9 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ninjurin PF04923.12 CBY19211.1 - 4.7e-05 23.3 7.8 6.2e-05 22.9 7.8 1.2 1 0 0 1 1 1 1 Ninjurin Serinc PF03348.15 CBY19211.1 - 0.22 10.4 6.3 0.27 10.1 6.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2207 PF09972.9 CBY19211.1 - 0.45 9.2 1.0 0.5 9.1 1.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKA2 PF16740.5 CBY19212.1 - 0.018 14.8 1.5 0.036 13.8 1.5 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 HALZ PF02183.18 CBY19212.1 - 0.12 12.7 0.8 0.27 11.5 0.8 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3450 PF11932.8 CBY19212.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MRP-S26 PF14943.6 CBY19213.1 - 2.6e-14 53.5 6.5 2.6e-14 53.5 6.5 2.9 3 0 0 3 3 3 2 Mitochondrial ribosome subunit S26 Prok-TraM PF09228.10 CBY19213.1 - 0.021 15.2 1.4 0.078 13.3 1.4 2.0 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM DUF2654 PF10849.8 CBY19213.1 - 0.047 13.9 3.0 0.063 13.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) bZIP_1 PF00170.21 CBY19214.1 - 8.5e-14 51.4 16.0 1.3e-13 50.8 16.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY19214.1 - 2e-07 31.0 16.8 2.9e-07 30.5 14.6 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY19214.1 - 2.7e-05 24.6 11.1 4.1e-05 24.0 11.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 CBY19214.1 - 0.0057 17.1 8.7 0.0057 17.1 8.7 1.8 1 1 1 2 2 2 1 Cell division protein ZapB BLOC1_2 PF10046.9 CBY19214.1 - 0.0074 16.6 2.3 0.013 15.8 2.3 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CBY19214.1 - 0.017 14.0 6.9 0.021 13.7 6.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RF-1 PF00472.20 CBY19214.1 - 0.039 13.9 5.0 0.066 13.1 5.1 1.4 1 1 0 1 1 1 0 RF-1 domain HAUS6_N PF14661.6 CBY19214.1 - 0.039 13.5 3.2 0.04 13.5 3.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.9 CBY19214.1 - 0.052 12.6 5.7 0.063 12.3 5.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pox_G5 PF04599.12 CBY19214.1 - 0.065 12.2 1.5 0.062 12.3 1.5 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein PspA_IM30 PF04012.12 CBY19214.1 - 0.065 12.8 9.3 0.18 11.3 9.3 1.7 1 1 0 1 1 1 0 PspA/IM30 family Spc24 PF08286.11 CBY19214.1 - 0.098 12.9 5.7 0.081 13.2 4.3 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Prominin PF05478.11 CBY19214.1 - 0.12 10.3 2.1 0.14 10.1 2.1 1.0 1 0 0 1 1 1 0 Prominin DUF3552 PF12072.8 CBY19214.1 - 0.16 11.4 11.1 0.21 11.0 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) YabA PF06156.13 CBY19214.1 - 0.37 11.4 6.5 0.36 11.5 5.4 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 CBY19214.1 - 0.59 9.9 10.3 0.12 12.2 4.0 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF737 PF05300.11 CBY19214.1 - 1.9 8.8 10.6 3.5 7.9 10.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF737) XhlA PF10779.9 CBY19214.1 - 3 8.1 5.2 1.4 9.2 2.6 1.7 1 1 1 2 2 2 0 Haemolysin XhlA Fe-ADH PF00465.19 CBY19215.1 - 3e-96 322.4 0.0 3.5e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBY19215.1 - 8.6e-12 45.3 0.0 6e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Syndecan PF01034.20 CBY19216.1 - 1e-07 31.8 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain MGAT2 PF05060.14 CBY19217.1 - 4.3e-15 55.6 0.0 4.9e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) MGAT2 PF05060.14 CBY19218.1 - 2.4e-14 53.2 0.1 3e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Methyltransf_10 PF05971.12 CBY19219.1 - 1.3e-08 34.5 0.0 1.6e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase Med23 PF11573.8 CBY19220.1 - 1.3e-193 646.0 36.1 2.9e-192 641.5 36.1 2.0 1 1 0 1 1 1 1 Mediator complex subunit 23 DUF3689 PF12463.8 CBY19221.1 - 6.6e-118 393.5 0.6 6.6e-118 393.5 0.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3689) Tmemb_18A PF09771.9 CBY19221.1 - 0.11 12.9 0.2 0.41 11.0 0.2 2.0 1 0 0 1 1 1 0 Transmembrane protein 188 WD40 PF00400.32 CBY19222.1 - 1.9e-28 98.1 11.1 3.8e-07 30.7 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CBY19222.1 - 1.4e-27 95.7 0.8 9.2e-27 93.1 0.3 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 CBY19222.1 - 0.00012 22.0 2.2 0.0012 18.8 0.1 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CBY19222.1 - 0.00071 19.8 2.8 0.11 12.9 0.1 3.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DBP10CT PF08147.12 CBY19222.1 - 0.15 12.3 0.6 1.9 8.8 0.1 2.8 3 0 0 3 3 3 0 DBP10CT (NUC160) domain HEAT PF02985.22 CBY19223.1 - 2.8e-31 104.9 18.7 0.0013 18.8 0.2 13.2 13 0 0 13 13 13 7 HEAT repeat HEAT_2 PF13646.6 CBY19223.1 - 5.5e-28 97.2 12.6 1.5e-07 31.7 0.3 6.8 3 2 4 7 7 7 7 HEAT repeats Cnd1 PF12717.7 CBY19223.1 - 4e-10 40.0 13.1 0.017 15.2 0.4 6.0 2 2 4 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CBY19223.1 - 7.6e-10 39.1 8.7 0.087 13.4 0.0 7.4 7 4 2 9 9 9 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CBY19223.1 - 1.4e-08 35.2 0.5 0.82 10.3 0.0 6.4 4 1 4 8 8 8 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CBY19223.1 - 4.3e-08 32.2 11.3 0.00055 18.6 2.1 3.2 3 0 0 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.8 CBY19223.1 - 6e-06 26.0 2.8 0.061 12.9 0.0 4.8 2 1 2 5 5 5 1 CLASP N terminal IFRD PF05004.13 CBY19223.1 - 7.2e-06 25.3 4.5 7e-05 22.1 0.0 3.6 3 2 1 4 4 4 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 CBY19223.1 - 0.0057 16.8 5.2 0.077 13.2 0.1 4.9 5 2 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 CBY19223.1 - 0.13 13.0 0.5 32 5.6 0.0 4.4 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat M11L PF11099.8 CBY19223.1 - 0.15 12.4 2.7 1.1 9.5 0.0 3.3 3 1 0 3 3 3 0 Apoptosis regulator M11L like MH2 PF03166.14 CBY19224.1 - 2.1e-24 86.8 0.0 2.7e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.9 CBY19224.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 Arm PF00514.23 CBY19227.1 - 3.4e-21 74.5 2.0 6.4e-06 26.0 0.0 6.3 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CBY19227.1 - 1.8e-07 31.1 3.1 0.0068 16.4 0.0 4.6 3 3 2 5 5 5 3 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 CBY19227.1 - 0.015 14.8 3.1 3.4 7.0 0.1 3.1 2 1 1 3 3 3 0 Armadillo-like Lactamase_B_6 PF16661.5 CBY19228.1 - 2.5e-47 160.8 0.0 7.1e-47 159.3 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CBY19228.1 - 1.4e-26 93.6 7.3 4.1e-26 92.2 0.0 3.6 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CBY19228.1 - 2e-18 66.7 0.1 5.1e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CBY19228.1 - 2e-11 43.6 0.0 4.5e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CBY19228.1 - 1.4e-06 28.4 0.1 7.3e-06 26.1 0.1 2.2 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Alpha_L_fucos PF01120.17 CBY19228.1 - 0.024 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-fucosidase Lactamase_B_2 PF12706.7 CBY19228.1 - 0.073 12.6 0.1 0.18 11.3 0.1 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Zip PF02535.22 CBY19229.1 - 5.3e-16 58.8 2.0 6e-16 58.6 2.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF21 PF01595.20 CBY19229.1 - 0.031 14.0 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Zip PF02535.22 CBY19230.1 - 1.6e-05 24.3 2.1 2e-05 24.0 2.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter TssN PF17555.2 CBY19230.1 - 0.0021 17.5 1.4 0.0025 17.3 1.4 1.1 1 0 0 1 1 1 1 Type VI secretion system, TssN EGF_CA PF07645.15 CBY19233.1 - 2.1e-153 498.3 402.0 4e-10 39.7 12.5 24.2 23 4 1 24 24 24 21 Calcium-binding EGF domain EGF_3 PF12947.7 CBY19233.1 - 9.6e-109 355.3 344.2 1.1e-08 35.1 7.7 22.7 22 0 0 22 22 22 21 EGF domain cEGF PF12662.7 CBY19233.1 - 1.4e-79 261.5 239.1 8.2e-08 32.0 4.7 23.3 22 0 0 22 22 22 19 Complement Clr-like EGF-like EGF PF00008.27 CBY19233.1 - 1.1e-31 108.7 303.7 0.00024 21.3 8.4 23.7 24 1 0 24 24 24 18 EGF-like domain hEGF PF12661.7 CBY19233.1 - 1.5e-18 66.7 273.7 0.00097 19.7 2.5 25.8 25 1 0 25 25 25 17 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY19233.1 - 3.5e-16 59.0 282.5 0.00039 20.4 4.7 21.8 22 0 0 22 22 22 16 MSP1 EGF domain 1 DUF4274 PF14096.6 CBY19233.1 - 0.047 13.7 0.7 12 6.0 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4274) FXa_inhibition PF14670.6 CBY19233.1 - 0.29 11.5 323.5 0.52 10.6 4.8 23.0 20 3 3 23 23 23 0 Coagulation Factor Xa inhibitory site Cadherin PF00028.17 CBY19234.1 - 4.8e-16 59.0 1.1 3.6e-05 24.1 0.1 5.5 6 0 0 6 6 6 3 Cadherin domain Ig_mannosidase PF17753.1 CBY19234.1 - 0.06 13.1 3.4 0.15 11.8 0.1 3.0 3 0 0 3 3 3 0 Ig-fold domain PhyH PF05721.13 CBY19235.1 - 6.6e-68 229.1 0.2 7.8e-68 228.9 0.2 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Asp_Arg_Hydrox PF05118.15 CBY19235.1 - 0.01 15.7 1.6 0.15 11.8 0.0 2.6 3 1 0 3 3 3 0 Aspartyl/Asparaginyl beta-hydroxylase SAM_2 PF07647.17 CBY19236.1 - 0.015 15.4 0.1 0.05 13.7 0.1 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Med26_C PF15693.5 CBY19237.1 - 1.2e-06 28.8 1.6 6.7e-06 26.4 1.6 2.3 1 1 0 1 1 1 1 Mediator complex subunit 26 C-terminal CytochromB561_N PF09786.9 CBY19237.1 - 0.11 11.5 11.6 0.12 11.3 11.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal zf-C2H2_2 PF12756.7 CBY19238.1 - 9.1e-25 86.9 0.2 2.1e-24 85.8 0.0 1.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Kelch_1 PF01344.25 CBY19239.1 - 6.1e-70 230.6 3.5 1.7e-15 56.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CBY19239.1 - 9.4e-40 133.6 1.6 3.7e-08 33.4 0.1 6.3 5 1 1 6 6 6 6 Kelch motif BTB PF00651.31 CBY19239.1 - 3.1e-30 104.6 1.2 6e-30 103.7 1.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY19239.1 - 2.7e-26 91.6 1.3 3.4e-26 91.3 0.3 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CBY19239.1 - 6.6e-21 73.4 3.9 3.5e-06 26.8 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 CBY19239.1 - 1.1e-19 70.2 5.0 1.3e-05 25.1 0.0 6.2 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY19239.1 - 2.2e-15 56.5 2.0 0.0015 18.7 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY19239.1 - 2.2e-08 33.9 0.9 3.1 7.9 0.0 6.1 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 CBY19239.1 - 0.0019 18.3 1.1 0.0059 16.8 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Glyoxal_oxid_N PF07250.11 CBY19239.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus PQQ_3 PF13570.6 CBY19239.1 - 0.71 10.4 3.4 65 4.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain TLD PF07534.16 CBY19240.1 - 9e-12 45.4 0.3 1.4e-11 44.8 0.3 1.3 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 CBY19240.1 - 0.0059 16.3 0.5 0.017 14.8 0.5 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MFS_1 PF07690.16 CBY19241.1 - 4.7e-22 78.4 57.9 1.9e-20 73.1 46.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily G-alpha PF00503.20 CBY19242.1 - 3.8e-87 292.7 10.9 4.7e-87 292.4 10.9 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY19242.1 - 4.2e-13 49.1 2.3 1.1e-08 34.7 0.5 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_24 PF13479.6 CBY19242.1 - 0.0024 17.6 0.1 0.0036 17.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 CBY19242.1 - 0.0031 17.7 1.0 1.9 8.7 0.3 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBY19242.1 - 0.015 15.4 1.4 2.1 8.4 0.0 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase DUF4309 PF14172.6 CBY19242.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) FtsK_SpoIIIE PF01580.18 CBY19242.1 - 0.066 12.6 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.23 CBY19242.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain LRR_4 PF12799.7 CBY19243.1 - 1.6e-12 47.4 8.4 2.2e-06 27.9 0.6 2.2 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY19243.1 - 1.1e-10 41.1 9.7 3.4e-05 23.5 0.6 2.2 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CBY19243.1 - 0.17 12.0 11.6 3.7 7.8 1.8 3.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.6 CBY19243.1 - 0.33 10.4 2.1 0.57 9.7 2.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 CBY19243.1 - 0.7 10.7 6.5 27 5.8 0.4 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat zf-C2H2 PF00096.26 CBY19244.1 - 1.3e-08 34.8 33.8 0.0013 19.0 0.4 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY19244.1 - 2.6e-06 27.8 35.7 0.0021 18.7 0.2 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY19244.1 - 0.0021 18.4 0.0 0.0021 18.4 0.0 5.4 6 0 0 6 6 5 2 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 CBY19244.1 - 0.018 14.7 24.5 0.065 12.9 0.1 5.7 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HC_2 PF13913.6 CBY19244.1 - 0.047 13.6 0.0 0.047 13.6 0.0 4.0 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-met PF12874.7 CBY19244.1 - 0.078 13.4 3.1 4.4 7.8 0.2 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type A2L_zn_ribbon PF08792.10 CBY19244.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2_6 PF13912.6 CBY19244.1 - 0.41 10.7 0.1 0.41 10.7 0.1 5.1 6 0 0 6 6 6 0 C2H2-type zinc finger OrsD PF12013.8 CBY19244.1 - 0.52 10.8 17.6 7 7.1 0.1 4.8 3 2 2 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D Ribosomal_L37e PF01907.19 CBY19244.1 - 0.72 10.1 5.6 1.8 8.7 0.2 3.6 4 0 0 4 4 4 0 Ribosomal protein L37e zf-C2H2_2 PF12756.7 CBY19244.1 - 1.2 9.5 14.4 2.3 8.6 3.9 4.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY19244.1 - 4.1 7.8 12.8 4.3 7.7 0.3 5.1 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CAP_GLY PF01302.25 CBY19245.1 - 3.3e-47 158.4 4.1 2.7e-23 81.8 0.2 2.4 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 CBY19245.1 - 2.8e-07 30.2 6.6 5.7e-07 29.3 6.6 1.5 1 0 0 1 1 1 1 CLIP1 zinc knuckle SlyX PF04102.12 CBY19245.1 - 0.29 11.8 0.0 0.29 11.8 0.0 13.4 7 5 7 16 16 16 0 SlyX FSH1 PF03959.13 CBY19246.1 - 1.9e-52 178.0 0.1 1e-51 175.6 0.1 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) FYVE PF01363.21 CBY19247.1 - 2.9e-14 53.0 7.7 6.1e-14 51.9 7.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.32 CBY19247.1 - 6e-14 52.2 9.3 1.4e-06 28.9 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY19247.1 - 1.3e-06 28.6 0.2 0.057 13.7 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CBY19247.1 - 0.0066 15.2 0.5 0.069 11.9 0.0 2.7 3 0 0 3 3 3 1 Nup133 N terminal like DUF326 PF03860.16 CBY19247.1 - 1.1 9.3 9.3 12 6.0 9.1 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF326) PSP94 PF05825.11 CBY19248.1 - 0.0003 21.3 7.8 0.00054 20.5 7.8 1.4 1 1 0 1 1 1 1 Beta-microseminoprotein (PSP-94) DUF4802 PF16060.5 CBY19248.1 - 0.042 14.0 3.4 0.089 13.0 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) MoCF_biosynth PF00994.24 CBY19250.1 - 2.9e-29 101.6 0.0 8e-29 100.2 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 CBY19250.1 - 9.1e-24 84.4 0.1 1.1e-21 77.7 0.1 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF1609 PF07753.11 CBY19250.1 - 0.0035 16.9 0.3 0.0053 16.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1609) DUF3164 PF11363.8 CBY19250.1 - 0.004 16.8 0.3 0.24 11.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3164) MH2 PF03166.14 CBY19251.1 - 7.9e-72 241.4 0.9 1.2e-71 240.8 0.9 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CBY19251.1 - 4.1e-36 123.3 2.3 8.9e-36 122.2 2.3 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 CBY19251.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-regulatory factor 3 DZF PF07528.14 CBY19252.1 - 3.8e-42 144.6 0.0 5.7e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 DZF domain dsrm PF00035.26 CBY19252.1 - 4.2e-07 30.6 1.7 2.4e-06 28.2 0.2 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CBY19252.1 - 0.035 14.3 4.2 1 9.6 0.2 3.4 3 0 0 3 3 3 0 Dicer dimerisation domain SIKE PF05769.11 CBY19252.1 - 0.044 13.7 0.4 2.9 7.8 0.1 2.4 2 0 0 2 2 2 0 SIKE family Iso_dh PF00180.20 CBY19253.1 - 2.8e-105 352.3 0.0 3.2e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sulfatase PF00884.23 CBY19254.1 - 2.3e-59 201.3 0.2 2.9e-59 201.0 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CBY19254.1 - 0.0035 18.1 0.0 0.0078 16.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 CBY19254.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function PurA PF04845.13 CBY19255.1 - 1.4e-78 263.2 0.1 1.6e-78 263.0 0.1 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 CBY19255.1 - 0.0013 18.9 0.1 2 8.5 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3276) Fip1 PF05182.13 CBY19256.1 - 5.2e-21 73.9 0.6 8.7e-21 73.2 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif SMAP PF15477.6 CBY19257.1 - 0.057 14.4 0.1 0.057 14.4 0.1 2.9 3 0 0 3 3 3 0 Small acidic protein family TEX19 PF15553.6 CBY19257.1 - 1.1 9.2 10.8 0.66 9.9 6.8 2.5 1 1 1 2 2 2 0 Testis-expressed protein 19 Apolipoprotein PF01442.18 CBY19258.1 - 0.0031 17.4 4.3 0.0031 17.4 4.3 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain An_peroxidase PF03098.15 CBY19258.1 - 0.024 13.2 0.3 0.042 12.4 0.3 1.3 1 0 0 1 1 1 0 Animal haem peroxidase Med19 PF10278.9 CBY19259.1 - 4.2e-22 78.9 4.7 4.2e-22 78.9 4.7 2.0 1 1 1 2 2 2 1 Mediator of RNA pol II transcription subunit 19 DAG_kinase_N PF14513.6 CBY19259.1 - 0.00052 20.3 4.0 0.0016 18.7 4.0 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase N-terminus SR-25 PF10500.9 CBY19259.1 - 0.13 11.8 13.1 0.17 11.5 13.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CBY19259.1 - 0.48 11.1 13.4 0.73 10.5 13.4 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Far-17a_AIG1 PF04750.14 CBY19260.1 - 1.4e-26 93.1 13.1 1.7e-26 92.8 13.1 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Far-17a_AIG1 PF04750.14 CBY19262.1 - 1.9e-18 66.5 7.7 1.9e-18 66.5 7.7 1.4 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein His_Phos_2 PF00328.22 CBY19263.1 - 2.3e-29 102.9 1.9 1.7e-25 90.2 1.3 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) CDH1_2_SANT_HL1 PF18375.1 CBY19263.1 - 0.046 14.4 0.2 0.11 13.2 0.0 1.7 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Complex1_LYR PF05347.15 CBY19264.1 - 4.2e-08 33.1 0.5 1.3e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBY19264.1 - 0.0076 17.0 1.3 0.011 16.5 1.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like TruD PF01142.18 CBY19265.1 - 3.4e-40 138.2 3.2 3.6e-35 121.6 0.3 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) HATPase_c_3 PF13589.6 CBY19266.1 - 6.9e-17 61.6 0.2 2.2e-16 59.9 0.1 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Morc6_S5 PF17942.1 CBY19266.1 - 1.3e-10 41.5 3.2 0.00043 20.3 0.0 3.3 3 0 0 3 3 3 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 CBY19266.1 - 0.00023 21.1 2.4 0.00051 20.0 2.4 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger CBM64 PF18666.1 CBY19266.1 - 0.092 12.8 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 64 Seryl_tRNA_N PF02403.22 CBY19266.1 - 1.7 8.9 24.1 1.8 8.8 7.7 4.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CREPT PF16566.5 CBY19266.1 - 9 6.5 13.6 0.31 11.2 0.8 3.7 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour RhoGAP PF00620.27 CBY19267.1 - 3.6e-34 117.8 0.4 8.2e-34 116.6 0.4 1.6 1 0 0 1 1 1 1 RhoGAP domain PH_9 PF15410.6 CBY19267.1 - 5.8e-11 42.8 0.0 1.9e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CBY19267.1 - 5.3e-07 30.1 3.1 6.2e-07 29.9 0.0 2.6 3 0 0 3 3 3 1 PH domain Serglycin PF04360.12 CBY19267.1 - 0.017 15.0 0.4 0.051 13.5 0.4 1.8 1 0 0 1 1 1 0 Serglycin Chlam_OMP3 PF03503.13 CBY19267.1 - 0.037 14.3 0.2 0.09 13.1 0.2 1.6 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 MAM PF00629.23 CBY19269.1 - 6.6e-11 42.4 0.0 1.3e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Sushi PF00084.20 CBY19269.1 - 0.00014 22.3 6.3 0.044 14.4 0.2 2.8 2 1 0 2 2 2 2 Sushi repeat (SCR repeat) Dicty_REP PF05086.12 CBY19269.1 - 0.29 9.1 9.4 0.4 8.6 9.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein 7tm_1 PF00001.21 CBY19270.1 - 1e-08 34.8 3.8 1e-08 34.8 3.8 2.8 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CBY19270.1 - 0.015 14.7 16.4 0.02 14.3 11.2 2.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx YwiC PF14256.6 CBY19270.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.0 3 2 1 4 4 4 0 YwiC-like protein zf-Tim10_DDP PF02953.15 CBY19271.1 - 2.1e-10 40.1 1.9 3.9e-10 39.2 1.9 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Abhydrolase_6 PF12697.7 CBY19272.1 - 0.019 15.6 0.0 0.019 15.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family TetR_C_23 PF17931.1 CBY19273.1 - 0.012 15.8 0.1 0.02 15.0 0.1 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Nop52 PF05997.12 CBY19273.1 - 0.087 12.6 0.8 5 6.8 0.1 2.2 2 0 0 2 2 2 0 Nucleolar protein,Nop52 Nup84_Nup100 PF04121.13 CBY19274.1 - 1.5e-18 66.3 7.1 1.6e-16 59.6 7.2 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 THUMP PF02926.17 CBY19274.1 - 0.014 15.5 0.0 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 THUMP domain ANAPC4_WD40 PF12894.7 CBY19275.1 - 9.7e-14 51.4 0.0 1.3e-10 41.5 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBY19275.1 - 6.4e-07 28.8 0.2 0.00016 20.9 0.1 3.5 3 0 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 CBY19275.1 - 2.3e-05 25.1 0.0 42 5.2 0.0 6.1 5 0 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 CBY19275.1 - 0.00067 19.5 0.0 0.28 11.2 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat TPR_7 PF13176.6 CBY19275.1 - 0.0083 16.1 1.8 8.7 6.6 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF758 PF05527.11 CBY19276.1 - 2.2e-52 177.7 3.1 2.7e-52 177.4 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) CorA PF01544.18 CBY19276.1 - 0.076 12.3 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RNA_pol_Rpb4 PF03874.16 CBY19277.1 - 4.8e-25 88.3 0.5 6.8e-25 87.8 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DivIC PF04977.15 CBY19278.1 - 0.00018 21.2 9.9 0.013 15.2 2.4 4.4 3 1 1 4 4 4 1 Septum formation initiator DUF4201 PF13870.6 CBY19278.1 - 0.0011 18.7 16.7 0.0031 17.3 16.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Leu_zip PF15294.6 CBY19278.1 - 0.0025 17.4 14.5 0.0031 17.1 13.5 1.6 2 0 0 2 2 2 1 Leucine zipper bZIP_1 PF00170.21 CBY19278.1 - 0.018 15.1 16.1 1.4 9.1 0.8 4.0 3 1 0 3 3 3 0 bZIP transcription factor DUF1192 PF06698.11 CBY19278.1 - 0.031 14.3 1.3 1.1 9.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) YabA PF06156.13 CBY19278.1 - 0.049 14.3 11.6 0.54 10.9 1.7 2.7 1 1 1 2 2 2 0 Initiation control protein YabA DUF848 PF05852.11 CBY19278.1 - 0.066 13.3 6.5 0.18 11.9 6.5 1.8 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) IFP_35_N PF07334.13 CBY19278.1 - 0.071 13.2 0.7 0.071 13.2 0.7 3.1 1 1 2 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Csm1_N PF18504.1 CBY19278.1 - 0.13 12.6 16.0 0.75 10.2 6.7 3.3 1 1 1 2 2 2 0 Csm1 N-terminal domain ZapB PF06005.12 CBY19278.1 - 0.32 11.5 17.8 2.8 8.5 3.6 3.4 2 1 0 2 2 2 0 Cell division protein ZapB Peptidase_M2 PF01401.18 CBY19278.1 - 0.32 9.5 6.7 0.46 9.0 6.7 1.2 1 0 0 1 1 1 0 Angiotensin-converting enzyme DUF5082 PF16888.5 CBY19278.1 - 1.1 9.5 16.4 2.8 8.3 6.8 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 CBY19278.1 - 1.9 9.0 19.1 2.1 8.9 16.1 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Fzo_mitofusin PF04799.13 CBY19278.1 - 3.5 7.1 11.3 4.7 6.7 10.0 1.9 1 1 1 2 2 2 0 fzo-like conserved region DUF4140 PF13600.6 CBY19278.1 - 5.7 7.5 10.7 49 4.5 4.7 3.7 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) GrpE PF01025.19 CBY19278.1 - 6.6 6.4 16.9 0.27 10.9 3.6 2.8 1 1 1 2 2 2 0 GrpE DUF4407 PF14362.6 CBY19278.1 - 6.9 5.9 15.9 0.77 9.1 11.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 CBY19278.1 - 8.7 6.4 22.7 7.9 6.6 14.5 3.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 CBY19278.1 - 9.9 6.3 15.2 4.8 7.4 10.0 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MCM PF00493.23 CBY19279.1 - 1.8e-93 311.8 0.1 3.2e-93 311.0 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY19279.1 - 8e-31 106.5 0.3 1.4e-30 105.7 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBY19279.1 - 7.5e-23 80.8 1.8 2e-22 79.4 1.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBY19279.1 - 2.4e-11 44.1 0.2 8.9e-11 42.3 0.2 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY19279.1 - 1.6e-07 30.9 0.0 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBY19279.1 - 0.0035 17.2 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBY19279.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CBY19279.1 - 0.067 12.9 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2052 PF09747.9 CBY19279.1 - 0.14 12.3 15.1 0.052 13.7 9.5 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CNOT11 PF10155.9 CBY19280.1 - 1.7e-42 144.5 1.3 3.5e-42 143.5 1.3 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 YihI PF04220.12 CBY19280.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF1400 PF07176.11 CBY19280.1 - 0.33 11.3 1.9 1.7 9.0 0.1 2.7 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) EGF_CA PF07645.15 CBY19281.1 - 2.7e-71 235.5 150.3 1.2e-10 41.4 10.7 9.5 10 0 0 10 10 10 8 Calcium-binding EGF domain cEGF PF12662.7 CBY19281.1 - 8.3e-39 131.1 59.2 1.9e-06 27.7 4.4 9.2 8 0 0 8 8 8 8 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY19281.1 - 3.3e-17 62.4 135.9 0.00086 19.5 11.0 10.0 9 1 2 11 11 11 8 EGF domain FXa_inhibition PF14670.6 CBY19281.1 - 8.7e-11 41.9 122.6 0.01 16.1 11.4 9.3 8 1 1 9 9 9 7 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY19281.1 - 5e-08 33.3 95.7 0.0085 16.7 1.5 12.4 13 0 0 13 13 13 7 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY19281.1 - 5.3e-05 23.2 86.4 0.0068 16.4 7.0 9.5 9 0 0 9 9 9 6 MSP1 EGF domain 1 RTBV_P12 PF06361.11 CBY19281.1 - 0.11 13.0 0.1 1.1 9.6 0.0 2.7 2 1 0 3 3 3 0 Rice tungro bacilliform virus P12 protein EGF PF00008.27 CBY19281.1 - 0.15 12.4 105.7 0.068 13.5 3.9 11.3 5 4 5 11 11 11 0 EGF-like domain rve PF00665.26 CBY19282.1 - 1.9e-11 44.2 0.0 4.5e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Zeta_toxin PF06414.12 CBY19282.1 - 0.0094 15.3 0.1 0.032 13.5 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin DUF935 PF06074.12 CBY19282.1 - 0.055 12.2 1.8 0.1 11.3 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DDE_Tnp_IS240 PF13610.6 CBY19282.1 - 0.056 13.7 0.4 0.056 13.7 0.4 2.0 2 0 0 2 2 2 0 DDE domain PhoH PF02562.16 CBY19282.1 - 0.06 12.8 0.0 0.6 9.5 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein Sigma54_activat PF00158.26 CBY19282.1 - 0.11 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IFT43 PF15305.6 CBY19282.1 - 0.32 11.1 2.0 1 9.6 2.0 1.8 1 0 0 1 1 1 0 Intraflagellar transport protein 43 ResB PF05140.14 CBY19285.1 - 0.11 11.2 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 ResB-like family DTHCT PF08070.11 CBY19286.1 - 1.4 9.6 14.3 0.083 13.6 4.9 2.4 1 1 0 2 2 2 0 DTHCT (NUC029) region Zona_pellucida PF00100.23 CBY19289.1 - 4.1e-24 85.8 2.1 5e-24 85.5 2.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.6 CBY19289.1 - 0.0023 18.1 7.5 0.0078 16.5 7.5 2.0 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site G8 PF10162.9 CBY19291.1 - 7e-29 100.4 0.0 1.5e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 G8 domain TIG PF01833.24 CBY19291.1 - 3.8e-09 36.5 0.9 1.5e-08 34.6 0.9 2.1 1 0 0 1 1 1 1 IPT/TIG domain Beta_helix PF13229.6 CBY19291.1 - 6.9e-06 26.0 16.1 0.011 15.6 3.3 4.5 3 2 0 3 3 3 2 Right handed beta helix region Herpes_PAP PF03325.13 CBY19291.1 - 0.11 12.1 0.1 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein EGF_CA PF07645.15 CBY19292.1 - 5.7e-13 48.9 66.3 0.00024 21.2 4.7 7.0 6 1 1 7 7 7 4 Calcium-binding EGF domain EGF_3 PF12947.7 CBY19292.1 - 3e-09 36.9 19.6 6e-09 36.0 10.0 5.4 5 0 0 5 5 5 3 EGF domain cEGF PF12662.7 CBY19292.1 - 7.1e-07 29.0 5.8 4.7e-05 23.2 2.0 5.2 4 1 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY19292.1 - 6.1e-05 23.2 5.1 6.1e-05 23.2 5.1 5.5 4 1 1 5 5 5 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY19292.1 - 0.0023 18.2 57.6 0.016 15.5 2.9 6.7 5 1 1 6 6 6 3 EGF-like domain hEGF PF12661.7 CBY19292.1 - 0.0039 17.8 6.5 0.0039 17.8 6.5 7.1 7 0 0 7 7 7 3 Human growth factor-like EGF Pkinase PF00069.25 CBY19293.1 - 1.1e-08 34.7 0.1 2.3e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19293.1 - 1.4e-06 27.8 0.0 2.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY19294.1 - 2.1e-08 33.8 0.1 2.1e-08 33.8 0.1 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19294.1 - 1.5e-05 24.4 0.0 3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M16 PF00675.20 CBY19295.1 - 3.7e-35 121.1 1.4 9.5e-35 119.8 0.2 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CBY19295.1 - 2.4e-20 73.0 0.0 4.6e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CBY19295.1 - 1.5e-10 41.4 0.0 3.6e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain FCH PF00611.23 CBY19296.1 - 0.0018 18.5 0.1 0.0032 17.7 0.1 1.4 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5624 PF18538.1 CBY19296.1 - 0.3 11.2 1.2 3.9 7.6 1.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5624) 7tm_2 PF00002.24 CBY19297.1 - 1.5e-22 80.1 13.0 2.7e-22 79.3 13.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 CBY19297.1 - 9e-07 29.1 0.2 2.5e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.12 CBY19297.1 - 0.00028 20.6 0.6 0.00028 20.6 0.6 2.2 2 0 0 2 2 2 1 SUR7/PalI family DUF3328 PF11807.8 CBY19297.1 - 1.2 8.8 5.6 0.24 11.2 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) DUF1774 PF08611.10 CBY19297.1 - 2.6 8.4 6.8 0.38 11.1 2.0 2.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Choline_kinase PF01633.20 CBY19298.1 - 1.3e-18 67.4 0.1 3e-17 62.9 0.2 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 CBY19298.1 - 4.6e-09 36.0 0.1 6.6e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CBY19298.1 - 1.2e-08 35.2 0.0 2.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY19298.1 - 0.085 12.2 0.0 6.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CBY19298.1 - 0.17 11.2 0.2 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Sulfotransfer_4 PF17784.1 CBY19300.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain zf-C2H2 PF00096.26 CBY19301.1 - 1.8e-09 37.5 17.8 0.0018 18.6 3.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY19301.1 - 1.6e-07 31.4 2.2 1.6e-07 31.4 2.2 4.1 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY19301.1 - 2e-06 28.2 18.9 0.0054 17.5 0.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY19301.1 - 2.8e-06 27.5 6.5 0.057 13.8 0.5 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY19301.1 - 0.0035 17.6 11.5 0.21 11.9 0.4 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY19301.1 - 1.1 9.6 10.4 4.8 7.6 0.9 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CBY19301.1 - 9.4 6.4 12.5 5.1 7.2 1.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger MARVEL PF01284.23 CBY19302.1 - 7.8e-07 29.2 10.5 1.6e-06 28.2 10.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain DctQ PF04290.12 CBY19302.1 - 0.0063 16.4 0.5 0.0063 16.4 0.5 2.0 1 1 1 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component Ferric_reduct PF01794.19 CBY19302.1 - 0.019 15.1 4.2 1.6 8.8 4.2 2.4 1 1 0 1 1 1 0 Ferric reductase like transmembrane component TspO_MBR PF03073.15 CBY19302.1 - 0.09 12.8 4.3 0.046 13.8 1.6 1.8 1 1 1 2 2 2 0 TspO/MBR family LIM PF00412.22 CBY19303.1 - 2.3e-43 146.2 52.5 1.9e-11 44.0 1.1 4.3 4 0 0 4 4 4 4 LIM domain DUF5566 PF17721.1 CBY19303.1 - 0.00085 19.7 0.1 0.0025 18.1 0.0 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5566) Pup PF05639.11 CBY19303.1 - 0.069 14.1 1.3 0.069 14.1 1.3 2.7 3 1 0 3 3 3 0 Pup-like protein Osmo_CC PF08946.10 CBY19303.1 - 0.11 12.7 0.1 0.4 11.0 0.1 1.9 1 0 0 1 1 1 0 Osmosensory transporter coiled coil GET2 PF08690.10 CBY19303.1 - 1.3 8.7 5.9 2 8.0 1.7 2.0 1 1 1 2 2 2 0 GET complex subunit GET2 FAD_binding_1 PF00667.20 CBY19304.1 - 5.5e-49 166.7 0.0 9.6e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CBY19304.1 - 1.2e-15 58.1 0.0 2.1e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ribonuc_2-5A PF06479.12 CBY19304.1 - 0.049 13.8 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease 2-5A TrmB PF01978.19 CBY19304.1 - 0.13 12.1 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Ras PF00071.22 CBY19305.1 - 2.7e-56 189.7 0.5 3.5e-56 189.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY19305.1 - 3.2e-35 121.0 0.2 5.9e-35 120.1 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY19305.1 - 3.3e-16 59.2 0.1 4.3e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY19305.1 - 8.5e-08 32.0 0.2 8.4e-07 28.7 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBY19305.1 - 1.2e-07 31.3 0.2 2.8e-07 30.1 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY19305.1 - 6.6e-06 26.2 0.1 1.1e-05 25.5 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY19305.1 - 0.00013 21.9 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CBY19305.1 - 0.00051 19.6 0.3 0.01 15.4 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CBY19305.1 - 0.0013 18.1 0.2 0.0017 17.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CBY19305.1 - 0.032 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 CBY19305.1 - 0.04 13.7 0.6 0.22 11.3 0.6 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CBY19305.1 - 0.048 13.9 0.0 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TIR_2 PF13676.6 CBY19305.1 - 0.11 13.1 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 TIR domain Flavodoxin_1 PF00258.25 CBY19306.1 - 1.8e-32 112.5 0.3 2.8e-32 111.9 0.3 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 CBY19306.1 - 1.1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Tmemb_55A PF09788.9 CBY19307.1 - 3.5e-37 127.8 14.1 4.6e-37 127.4 14.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 55A VIT1 PF01988.19 CBY19307.1 - 0.0034 17.3 0.1 0.0041 17.0 0.1 1.1 1 0 0 1 1 1 1 VIT family PhoLip_ATPase_C PF16212.5 CBY19307.1 - 0.0047 16.7 0.3 0.0058 16.4 0.3 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal DUF3593 PF12159.8 CBY19307.1 - 0.024 14.6 0.5 0.042 13.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Phage_holin_3_6 PF07332.11 CBY19307.1 - 0.037 14.1 3.7 0.052 13.6 3.7 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Amastin PF07344.11 CBY19307.1 - 0.08 12.8 4.2 0.14 12.0 3.8 1.6 1 1 0 1 1 1 0 Amastin surface glycoprotein UPF0547 PF10571.9 CBY19307.1 - 0.092 12.8 14.9 3.8 7.7 0.2 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-dskA_traR PF01258.17 CBY19307.1 - 0.29 11.1 0.1 0.29 11.1 0.1 3.9 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger zinc_ribbon_5 PF13719.6 CBY19307.1 - 0.36 10.6 0.2 0.36 10.6 0.2 4.4 4 1 0 4 4 4 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 CBY19307.1 - 0.77 9.5 14.2 9.7 5.9 0.1 4.6 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zf_UBZ PF18439.1 CBY19307.1 - 0.89 9.2 0.1 0.89 9.2 0.1 4.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C4_Topoisom PF01396.19 CBY19307.1 - 3.3 7.6 16.2 2.9 7.7 0.0 4.5 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger DUF2464 PF10240.9 CBY19308.1 - 1.1e-31 110.3 0.2 8e-31 107.5 0.2 1.8 1 1 0 1 1 1 1 Multivesicular body subunit 12 FmiP_Thoc5 PF09766.9 CBY19309.1 - 4.5e-23 82.1 16.1 2.6e-18 66.4 12.8 2.3 1 1 1 2 2 2 2 Fms-interacting protein/Thoc5 LXG PF04740.12 CBY19309.1 - 0.011 15.4 2.8 0.041 13.6 0.3 2.2 1 1 0 2 2 2 0 LXG domain of WXG superfamily Seryl_tRNA_N PF02403.22 CBY19309.1 - 0.07 13.4 9.2 0.49 10.6 3.6 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MREG PF15812.5 CBY19309.1 - 0.071 13.4 1.4 0.09 13.1 0.1 1.8 2 0 0 2 2 2 0 Melanoregulin APCDDC PF14921.6 CBY19309.1 - 0.19 11.1 1.7 0.33 10.4 1.7 1.3 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 Phage_GP20 PF06810.11 CBY19309.1 - 0.29 10.9 6.8 3.6 7.4 0.0 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 Cauli_AT PF03233.13 CBY19309.1 - 0.43 10.5 4.9 1.1 9.1 0.2 2.4 1 1 0 2 2 2 0 Aphid transmission protein LXG PF04740.12 CBY19310.1 - 0.03 14.0 0.2 0.034 13.8 0.2 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Gp-FAR-1 PF05823.12 CBY19310.1 - 0.045 14.1 0.2 0.052 13.9 0.2 1.1 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ER PF01133.17 CBY19310.1 - 0.063 13.3 0.2 2.2 8.4 0.2 2.3 1 1 0 1 1 1 0 Enhancer of rudimentary Cauli_AT PF03233.13 CBY19310.1 - 0.067 13.1 0.2 0.072 13.0 0.2 1.2 1 0 0 1 1 1 0 Aphid transmission protein kleA_kleC PF17383.2 CBY19310.1 - 0.16 12.3 0.0 0.23 11.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized KorC regulated protein A Trehalase PF01204.18 CBY19312.1 - 0.0031 16.4 1.0 0.0036 16.2 1.0 1.1 1 0 0 1 1 1 1 Trehalase DUF5078 PF16877.5 CBY19312.1 - 0.13 12.7 0.6 0.18 12.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) Spore_III_AB PF09548.10 CBY19312.1 - 1.4 9.1 8.1 1.7 8.7 8.1 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) CCDC-167 PF15188.6 CBY19312.1 - 2.3 8.6 14.6 3.3 8.1 6.5 2.4 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 FUSC PF04632.12 CBY19312.1 - 2.5 6.5 4.5 3.1 6.2 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.13 CBY19312.1 - 4.7 6.4 9.9 5.8 6.1 9.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 CBY19312.1 - 5.4 6.5 13.4 6.8 6.2 13.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM184 PF15665.5 CBY19313.1 - 0.00028 20.7 1.0 0.00028 20.7 1.0 4.4 1 1 3 4 4 4 2 Family with sequence similarity 184, A and B Jnk-SapK_ap_N PF09744.9 CBY19313.1 - 0.0041 17.4 16.9 0.0041 17.4 16.9 5.2 1 1 4 5 5 5 2 JNK_SAPK-associated protein-1 YojJ PF10372.9 CBY19313.1 - 0.95 9.6 8.9 0.29 11.3 0.2 3.7 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF4407 PF14362.6 CBY19313.1 - 1.9 7.7 35.2 0.23 10.8 13.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) UCH_1 PF13423.6 CBY19314.1 - 4e-68 230.4 0.3 5.8e-68 229.8 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CBY19314.1 - 3e-17 63.6 0.0 5.6e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Cation_efflux PF01545.21 CBY19314.1 - 1.8e-09 37.6 20.1 1.8e-09 37.6 20.1 1.9 2 0 0 2 2 2 1 Cation efflux family UCH PF00443.29 CBY19314.1 - 1.7e-07 31.0 0.2 2.9e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase bZIP_2 PF07716.15 CBY19316.1 - 5.3e-14 52.0 12.2 5.8e-14 51.9 10.6 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY19316.1 - 0.0027 17.8 8.4 0.0027 17.8 8.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor FXR_C1 PF16096.5 CBY19316.1 - 0.097 12.9 4.0 0.35 11.1 4.0 1.9 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 ABC_membrane PF00664.23 CBY19317.1 - 2.2e-55 188.2 9.9 2.2e-55 188.2 9.9 1.6 2 0 0 2 2 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBY19317.1 - 1.9e-31 109.4 0.1 3.6e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBY19317.1 - 7.4e-09 35.4 5.4 3.9e-07 29.7 5.4 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY19317.1 - 2.8e-05 24.6 0.1 6.2e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CBY19317.1 - 0.00059 19.5 0.4 0.33 10.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CBY19317.1 - 0.0032 17.7 0.7 0.026 14.8 0.7 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CBY19317.1 - 0.0055 17.1 0.9 0.21 12.0 0.9 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CBY19317.1 - 0.016 14.4 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 CBY19317.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 CBY19317.1 - 0.07 12.4 0.1 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 CBY19317.1 - 0.071 12.9 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MoaE PF02391.17 CBY19317.1 - 0.083 13.2 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 MoaE protein AAA_30 PF13604.6 CBY19317.1 - 0.13 12.0 1.5 0.87 9.3 0.9 2.3 1 1 0 1 1 1 0 AAA domain ABC_membrane_3 PF13748.6 CBY19317.1 - 0.13 11.4 3.3 0.26 10.5 3.3 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region LapA_dom PF06305.11 CBY19317.1 - 9.4 6.1 9.9 34 4.4 0.7 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain LIDHydrolase PF10230.9 CBY19318.1 - 4.1e-22 79.0 1.0 5.2e-22 78.7 1.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipin_mid PF16876.5 CBY19318.1 - 0.087 13.0 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Complex1_LYR PF05347.15 CBY19320.1 - 8.3e-05 22.6 0.1 9e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBY19320.1 - 0.03 15.1 0.1 0.034 14.9 0.1 1.1 1 0 0 1 1 1 0 Complex1_LYR-like Glyco_transf_54 PF04666.13 CBY19321.1 - 2.7e-82 275.9 0.0 3.9e-82 275.4 0.0 1.2 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_tranf_2_3 PF13641.6 CBY19321.1 - 0.0027 17.6 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pkinase PF00069.25 CBY19322.1 - 1.6e-35 122.8 0.0 2.5e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19322.1 - 1.3e-28 100.0 0.4 5e-28 98.1 0.4 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 CBY19322.1 - 3.2e-06 26.5 0.0 1.1e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 CBY19322.1 - 0.00058 18.8 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CBY19322.1 - 0.038 13.6 0.1 0.086 12.5 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF3951 PF13131.6 CBY19322.1 - 0.047 13.9 0.6 0.096 12.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) APH PF01636.23 CBY19322.1 - 0.17 11.7 0.0 0.69 9.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.21 CBY19323.1 - 1.4e-27 96.3 0.2 1.6e-27 96.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY19323.1 - 5.5e-10 39.5 0.1 6.6e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY19323.1 - 6.3e-09 35.6 0.0 7.2e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY19323.1 - 8.6e-07 28.4 0.2 0.0028 16.9 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY19323.1 - 3.1e-05 23.5 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY19323.1 - 0.0014 18.0 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region T2SSE PF00437.20 CBY19323.1 - 0.024 13.7 0.1 0.032 13.3 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein 6PF2K PF01591.18 CBY19323.1 - 0.039 13.3 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NTPase_1 PF03266.15 CBY19323.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.4 1 1 1 2 2 2 0 NTPase DAG1 PF05454.11 CBY19324.1 - 2.6e-06 27.0 0.3 6.5e-06 25.7 0.3 1.6 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Chordopox_A13L PF05961.11 CBY19324.1 - 0.099 12.9 0.3 0.25 11.6 0.3 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Gram_pos_anchor PF00746.21 CBY19324.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF5316 PF17247.2 CBY19324.1 - 0.22 11.6 0.3 0.48 10.5 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5316) p450 PF00067.22 CBY19325.1 - 3.4e-20 72.2 0.1 4.9e-18 65.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 CortBP2 PF09727.9 CBY19328.1 - 1.8e-40 138.9 24.4 1.8e-40 138.9 24.4 5.8 1 1 1 5 5 5 2 Cortactin-binding protein-2 Clathrin PF00637.20 CBY19330.1 - 2.9e-09 36.9 25.3 0.14 12.0 0.1 9.7 5 2 4 10 10 10 4 Region in Clathrin and VPS TPR_12 PF13424.6 CBY19330.1 - 0.045 14.0 20.9 21 5.5 0.0 9.8 13 1 0 13 13 13 0 Tetratricopeptide repeat DUF410 PF04190.13 CBY19330.1 - 0.15 11.9 21.9 2.3 7.9 0.0 6.0 2 1 1 5 5 5 0 Protein of unknown function (DUF410) ANAPC3 PF12895.7 CBY19330.1 - 0.84 9.9 19.3 11 6.3 0.0 7.9 5 3 3 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CBY19330.1 - 2 9.4 14.6 1.1e+02 4.1 0.3 8.4 6 5 5 11 11 11 0 Tetratricopeptide repeat Sec16_C PF12931.7 CBY19330.1 - 2.9 7.4 10.3 2 8.0 1.6 4.3 3 2 0 3 3 3 0 Sec23-binding domain of Sec16 LIM PF00412.22 CBY19331.1 - 3.2e-50 168.2 77.6 9.6e-15 54.6 3.7 5.5 5 1 0 5 5 5 5 LIM domain RNA_pol_3_Rpc31 PF11705.8 CBY19331.1 - 0.075 13.3 1.4 0.12 12.6 1.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ANAPC4_WD40 PF12894.7 CBY19332.1 - 7.4e-11 42.2 0.0 0.38 11.1 0.0 6.1 3 3 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY19332.1 - 2.3e-10 40.9 2.0 0.03 15.2 0.0 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CBY19332.1 - 0.00079 18.6 1.6 0.0075 15.4 0.0 3.0 4 1 0 4 4 4 1 Coatomer WD associated region IKI3 PF04762.12 CBY19332.1 - 0.014 13.4 0.0 0.81 7.6 0.0 3.0 3 1 0 3 3 3 0 IKI3 family PD40 PF07676.12 CBY19332.1 - 0.031 14.2 0.1 16 5.5 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF2448 PF10476.9 CBY19333.1 - 0.058 13.3 4.2 0.069 13.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Prenyltransf PF01255.19 CBY19334.1 - 6.7e-72 241.6 0.0 8.2e-72 241.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3072 PF11272.8 CBY19334.1 - 0.2 11.6 0.3 9.7 6.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3072) CNDH2_N PF06278.11 CBY19335.1 - 5.6e-07 29.8 0.1 1.6e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal EppA_BapA PF07268.11 CBY19335.1 - 0.023 14.6 0.1 0.023 14.6 0.1 1.9 2 1 1 3 3 3 0 Exported protein precursor (EppA/BapA) CNDH2_C PF16858.5 CBY19336.1 - 1.8e-08 34.7 7.3 7.6e-08 32.6 0.0 3.3 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 CBY19336.1 - 3.3e-06 27.3 0.0 1.2e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal EppA_BapA PF07268.11 CBY19336.1 - 0.047 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) Ion_trans PF00520.31 CBY19337.1 - 1.2e-18 67.3 17.1 2.4e-18 66.3 17.1 1.5 1 0 0 1 1 1 1 Ion transport protein YdjM PF04307.14 CBY19337.1 - 0.0045 16.3 0.4 2.3 7.5 0.0 2.7 2 0 0 2 2 2 2 LexA-binding, inner membrane-associated putative hydrolase 2TM PF13239.6 CBY19337.1 - 0.15 12.3 2.0 0.92 9.9 2.0 2.4 1 0 0 1 1 1 0 2TM domain Bromodomain PF00439.25 CBY19338.1 - 6.4e-40 135.1 3.7 2.1e-19 69.4 0.3 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CBY19338.1 - 1.6e-24 85.8 1.1 1.6e-24 85.8 1.1 2.3 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Carn_acyltransf PF00755.20 CBY19339.1 - 7.7e-128 427.7 0.0 9e-128 427.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CSN8_PSD8_EIF3K PF10075.9 CBY19340.1 - 6.6e-31 107.2 0.5 1e-30 106.6 0.5 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CBY19340.1 - 1.8e-07 30.8 1.6 2.4e-07 30.4 1.6 1.1 1 0 0 1 1 1 1 SAC3/GANP family IQ PF00612.27 CBY19341.1 - 0.0016 18.0 0.2 0.0016 18.0 0.2 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Na_Ca_ex_C PF16494.5 CBY19341.1 - 0.047 14.2 2.6 0.55 10.7 0.1 2.8 3 0 0 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain Cytochrom_C1 PF02167.15 CBY19342.1 - 1.4e-69 234.2 0.0 1.6e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CBY19342.1 - 0.0025 18.1 0.0 0.0073 16.6 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III T2SSF PF00482.23 CBY19342.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Myosin_head PF00063.21 CBY19344.1 - 3.6e-264 878.1 0.1 3.6e-264 878.1 0.1 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY19344.1 - 1.1e-144 483.8 247.1 1.5e-144 483.3 247.1 1.1 1 0 0 1 1 1 1 Myosin tail DUF3584 PF12128.8 CBY19344.1 - 0.00013 19.7 45.6 0.00013 19.7 45.6 5.0 1 1 2 4 4 4 1 Protein of unknown function (DUF3584) Myosin_N PF02736.19 CBY19344.1 - 0.001 18.8 1.8 0.0028 17.5 1.8 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Sec2p PF06428.11 CBY19344.1 - 0.0066 16.4 6.5 0.0066 16.4 6.5 14.7 3 3 11 15 15 15 3 GDP/GTP exchange factor Sec2p IQ PF00612.27 CBY19344.1 - 0.057 13.2 1.3 2.7 8.0 0.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY19344.1 - 0.25 11.6 0.0 0.25 11.6 0.0 4.6 4 1 2 6 6 6 0 AAA domain AAA_16 PF13191.6 CBY19344.1 - 0.69 10.3 0.0 0.69 10.3 0.0 5.8 3 2 0 3 3 3 0 AAA ATPase domain Forkhead PF00250.18 CBY19345.1 - 2.4e-37 127.0 1.5 3.4e-37 126.6 0.1 1.9 2 0 0 2 2 2 1 Forkhead domain TMEM65 PF10507.9 CBY19346.1 - 4.5e-44 148.8 0.7 7.2e-44 148.2 0.7 1.3 1 0 0 1 1 1 1 Transmembrane protein 65 PLAT PF01477.23 CBY19347.1 - 5.4e-12 46.3 0.1 8e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.11 CBY19347.1 - 0.00013 21.9 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) Pkinase PF00069.25 CBY19348.1 - 4.1e-53 180.4 0.0 5.5e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19348.1 - 5.6e-34 117.6 0.0 7.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 CBY19348.1 - 6.4e-20 71.4 0.1 1.2e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 CBY19348.1 - 4.3e-06 26.3 0.0 8.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY19348.1 - 0.00073 18.4 0.0 0.0017 17.2 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY19348.1 - 0.00099 18.1 1.1 0.029 13.3 0.0 2.7 2 1 0 3 3 3 1 Haspin like kinase domain PI3K_C2 PF00792.24 CBY19348.1 - 0.045 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 APH PF01636.23 CBY19348.1 - 0.066 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_1 PF00130.22 CBY19349.1 - 2.3e-29 101.0 18.6 1e-16 60.5 9.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGEF PF00621.20 CBY19349.1 - 1.5e-12 48.1 1.4 2.6e-12 47.3 1.4 1.4 1 0 0 1 1 1 1 RhoGEF domain PHD_4 PF16866.5 CBY19349.1 - 0.0065 16.5 6.6 1.3 9.2 0.1 3.2 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 CBY19349.1 - 0.015 14.9 18.4 0.015 14.8 2.0 3.3 4 0 0 4 4 4 0 PHD-finger Zf_RING PF16744.5 CBY19349.1 - 0.019 15.0 10.0 0.16 12.1 1.2 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 CBY19349.1 - 0.043 14.1 15.2 0.79 10.1 3.4 2.6 2 0 0 2 2 2 0 C1 domain Corona_NSP4_C PF16348.5 CBY19349.1 - 0.08 13.8 0.2 0.19 12.5 0.2 1.6 1 0 0 1 1 1 0 Coronavirus nonstructural protein 4 C-terminus Alpha-amylase PF00128.24 CBY19349.1 - 0.11 12.0 0.4 0.15 11.6 0.4 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain PHD PF00628.29 CBY19349.1 - 0.13 12.1 14.6 0.6 10.0 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 CBY19349.1 - 0.19 11.9 13.9 2.8 8.2 1.4 3.3 2 1 1 3 3 3 0 FYVE-type zinc finger zf-C2HC5 PF06221.13 CBY19349.1 - 0.64 10.1 9.3 6 6.9 1.6 2.6 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Sulfotransfer_3 PF13469.6 CBY19351.1 - 0.0029 18.0 0.0 0.0098 16.3 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY19351.1 - 0.034 13.6 0.1 0.077 12.5 0.0 1.6 2 0 0 2 2 2 0 Sulfotransferase domain IFS PF16718.5 CBY19351.1 - 0.12 12.4 2.9 0.16 12.1 0.5 2.1 2 1 0 2 2 2 0 Immunity factor for SPN ATG22 PF11700.8 CBY19351.1 - 0.21 10.2 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Na_H_Exchanger PF00999.21 CBY19353.1 - 2.9e-73 246.9 31.6 3.3e-73 246.7 31.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ras PF00071.22 CBY19354.1 - 8.1e-36 123.1 0.0 9.1e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY19354.1 - 8.1e-30 103.5 0.0 1e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY19354.1 - 1.6e-06 27.7 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY19354.1 - 1.8e-05 24.8 0.0 2.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY19354.1 - 0.0012 19.2 0.1 0.0016 18.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBY19354.1 - 0.0029 17.5 0.3 0.0082 16.1 0.3 1.7 1 1 1 2 2 2 1 RsgA GTPase ParA PF10609.9 CBY19354.1 - 0.0087 15.5 0.0 0.0098 15.4 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase NACHT PF05729.12 CBY19354.1 - 0.022 14.7 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 CBY19354.1 - 0.023 14.5 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 CBY19354.1 - 0.024 14.0 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CBY19354.1 - 0.025 14.9 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBY19354.1 - 0.025 14.3 0.1 0.038 13.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 CBY19354.1 - 0.027 13.7 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CBY19354.1 - 0.032 13.7 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 CBY19354.1 - 0.034 13.7 0.0 0.49 9.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain VirE PF05272.11 CBY19354.1 - 0.065 13.0 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Virulence-associated protein E ATP_bind_1 PF03029.17 CBY19354.1 - 0.087 12.6 0.3 5.9 6.6 0.2 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 CBY19354.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CBY19354.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF815) MeaB PF03308.16 CBY19354.1 - 0.14 11.1 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 CBY19354.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Ammonium_transp PF00909.21 CBY19355.1 - 1.1e-85 287.8 22.8 1.4e-85 287.5 22.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4818 PF16089.5 CBY19355.1 - 1.9 8.9 10.6 12 6.4 1.7 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4818) Sad1_UNC PF07738.13 CBY19356.1 - 9.9e-31 106.5 0.0 2.8e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Spc7 PF08317.11 CBY19356.1 - 0.023 13.6 0.7 0.035 13.0 0.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG17 PF04108.12 CBY19356.1 - 0.069 12.2 2.6 0.095 11.8 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF16 PF01519.16 CBY19356.1 - 2.3 8.7 5.2 5.6 7.5 4.9 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Nup88 PF10168.9 CBY19358.1 - 2.6e-20 71.9 17.4 2.1e-19 68.9 17.4 1.9 1 1 0 1 1 1 1 Nuclear pore component ZapA PF05164.13 CBY19358.1 - 0.021 15.3 4.9 0.041 14.3 4.4 1.9 1 1 0 1 1 1 0 Cell division protein ZapA HemY_N PF07219.13 CBY19358.1 - 0.13 12.5 0.3 0.24 11.6 0.3 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Nup54 PF13874.6 CBY19358.1 - 0.19 11.8 11.1 0.35 11.0 11.1 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF87 PF01935.17 CBY19358.1 - 0.38 10.8 5.4 0.29 11.2 3.4 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain DUF1451 PF07295.11 CBY19358.1 - 0.39 10.7 6.8 0.11 12.5 2.9 1.9 1 1 0 1 1 1 0 Zinc-ribbon containing domain Spc7 PF08317.11 CBY19358.1 - 0.49 9.2 14.2 0.33 9.8 12.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.6 CBY19358.1 - 1 9.8 7.8 2.2 8.8 7.8 1.6 1 0 0 1 1 1 0 AAA domain COG2 PF06148.11 CBY19358.1 - 1.6 8.9 7.0 2.1 8.4 5.6 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 CBY19358.1 - 1.7 8.7 12.1 0.92 9.6 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 CBY19358.1 - 2.4 7.6 9.7 3.6 7.1 9.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 CBY19358.1 - 2.6 8.1 14.4 0.41 10.7 4.5 2.4 1 1 1 2 2 2 0 Laminin Domain II GAS PF13851.6 CBY19358.1 - 3.1 7.1 18.3 1.2 8.4 3.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.21 CBY19358.1 - 3.8 8.1 10.8 3.2 8.3 2.4 2.5 1 1 1 2 2 2 0 Spectrin repeat THUMP PF02926.17 CBY19359.1 - 5e-05 23.4 1.1 0.00012 22.2 1.1 1.8 1 1 0 1 1 1 1 THUMP domain BTB PF00651.31 CBY19361.1 - 3.4e-26 91.7 0.1 5.9e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 CBY19361.1 - 2e-24 84.9 4.4 1.2e-05 24.8 0.2 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CBY19361.1 - 1.4e-21 76.0 6.6 0.00012 22.2 0.2 6.4 4 1 2 6 6 6 5 Kelch motif BACK PF07707.15 CBY19361.1 - 1.1e-17 64.0 0.7 2.4e-17 62.9 0.7 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CBY19361.1 - 1e-08 34.8 7.3 0.029 14.3 0.2 6.8 6 1 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 CBY19361.1 - 1.1e-07 31.9 5.7 0.062 13.6 0.1 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY19361.1 - 3.2e-06 27.0 8.2 0.007 16.4 0.2 4.6 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY19361.1 - 0.019 15.0 5.7 1.1 9.4 0.0 3.6 4 0 0 4 4 4 0 Kelch motif DUF3342 PF11822.8 CBY19361.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DUF3109 PF11307.8 CBY19361.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) PTB PF08416.13 CBY19362.1 - 2.7e-16 59.9 0.0 7.5e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 CBY19362.1 - 3e-10 40.1 0.1 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 SH2 domain Trypsin PF00089.26 CBY19364.1 - 2.3e-11 44.0 0.1 2.5e-11 43.8 0.1 1.0 1 0 0 1 1 1 1 Trypsin RRM_1 PF00076.22 CBY19365.1 - 4.9e-12 45.5 0.0 8.1e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY19365.1 - 0.0012 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY19365.1 - 0.0016 18.3 0.0 0.0021 17.9 0.0 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif Pkinase PF00069.25 CBY19366.1 - 3.6e-05 23.3 0.0 5e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19366.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 CBY19368.1 - 6.1e-29 101.2 0.7 7.5e-29 100.9 0.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19368.1 - 7.5e-24 84.4 0.4 9.2e-24 84.1 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Tudor_RapA PF18337.1 CBY19368.1 - 0.02 15.0 0.1 0.047 13.9 0.0 1.7 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain MRP-L47 PF06984.13 CBY19371.1 - 4.3e-09 36.4 0.8 8.6e-09 35.4 0.8 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Dynamitin PF04912.14 CBY19372.1 - 3.3e-23 82.6 12.5 1.6e-22 80.4 10.2 2.5 1 1 1 2 2 2 1 Dynamitin Trimer_CC PF08954.11 CBY19372.1 - 0.0074 15.8 0.3 0.042 13.4 0.0 2.3 2 0 0 2 2 2 1 Trimerisation motif Bacillus_HBL PF05791.11 CBY19372.1 - 0.02 14.7 3.9 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ABC_tran_CTD PF16326.5 CBY19372.1 - 0.038 14.2 10.7 1.1 9.6 1.9 3.5 3 1 0 3 3 2 0 ABC transporter C-terminal domain Occludin_ELL PF07303.13 CBY19372.1 - 0.041 14.6 1.5 2.2 9.1 0.0 2.8 1 1 1 3 3 3 0 Occludin homology domain RmuC PF02646.16 CBY19372.1 - 0.075 12.2 5.5 1.2 8.2 0.8 2.8 4 0 0 4 4 4 0 RmuC family DUF892 PF05974.12 CBY19372.1 - 0.087 12.8 4.3 3.4 7.7 1.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF892) Jnk-SapK_ap_N PF09744.9 CBY19372.1 - 0.3 11.3 7.4 0.19 11.9 2.3 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 PspB PF06667.12 CBY19372.1 - 0.44 10.6 5.0 21 5.2 1.1 3.5 3 0 0 3 3 3 0 Phage shock protein B Syntaxin-6_N PF09177.11 CBY19372.1 - 0.53 10.9 4.5 18 6.0 0.1 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 CBY19372.1 - 0.55 9.8 8.3 1.6 8.2 0.1 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Spectrin PF00435.21 CBY19372.1 - 1.2 9.7 10.2 14 6.3 0.1 3.6 3 1 0 3 3 3 0 Spectrin repeat CLZ PF16526.5 CBY19372.1 - 6.1 7.3 14.1 30 5.1 0.0 4.0 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 CBY19372.1 - 6.4 7.3 16.0 1.4 9.5 0.4 3.1 3 1 0 3 3 2 0 Cell division protein ZapB DUF2203 PF09969.9 CBY19372.1 - 8.7 7.1 8.2 8.2 7.2 1.6 2.8 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) ECH_1 PF00378.20 CBY19373.1 - 1.5e-83 280.0 0.3 1.7e-83 279.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY19373.1 - 2e-33 116.3 3.8 1.4e-30 106.9 0.5 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CBY19373.1 - 0.012 15.5 0.0 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Glyco_transf_49 PF13896.6 CBY19374.1 - 3.6e-101 338.8 0.5 3.6e-101 338.8 0.5 2.0 2 0 0 2 2 2 1 Glycosyl-transferase for dystroglycan SLC35F PF06027.12 CBY19375.1 - 2.3e-06 27.4 4.2 2.3e-06 27.4 4.2 2.3 2 1 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 CBY19375.1 - 3e-06 27.4 27.6 0.00033 20.9 8.1 3.3 3 1 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 CBY19375.1 - 9.7e-05 21.5 16.6 0.0084 15.1 16.6 2.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 CBY19375.1 - 0.00011 21.5 0.0 0.00023 20.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 CBY19375.1 - 0.011 15.1 0.3 0.011 15.1 0.3 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF3522 PF12036.8 CBY19375.1 - 0.33 11.2 8.4 0.13 12.5 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) DUF5090 PF17009.5 CBY19375.1 - 4.3 7.2 8.8 4.5 7.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Sprouty PF05210.13 CBY19378.1 - 0.22 11.9 3.5 0.41 11.1 3.5 1.4 1 0 0 1 1 1 0 Sprouty protein (Spry) RINGv PF12906.7 CBY19379.1 - 7.6e-14 51.6 7.5 1.4e-13 50.7 7.5 1.5 1 0 0 1 1 1 1 RING-variant domain DUF2157 PF09925.9 CBY19379.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) zf-RING_4 PF14570.6 CBY19379.1 - 9.1 6.2 8.9 26 4.7 8.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Sulfatase PF00884.23 CBY19381.1 - 1.4e-33 116.6 0.0 2.2e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CBY19381.1 - 0.00062 20.5 0.1 0.0015 19.2 0.1 1.7 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 CBY19381.1 - 0.031 14.2 0.0 0.085 12.8 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function AP3D1 PF06375.11 CBY19383.1 - 0.28 11.4 5.5 0.37 11.0 1.6 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 UCR_hinge PF02320.16 CBY19383.1 - 1.1 9.5 4.6 0.39 10.9 0.3 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein NDK PF00334.19 CBY19384.1 - 2.4e-12 47.0 0.0 0.00021 21.3 0.0 3.4 3 0 0 3 3 3 3 Nucleoside diphosphate kinase ChlI PF13541.6 CBY19384.1 - 0.0082 16.0 0.0 0.9 9.4 0.0 2.6 3 0 0 3 3 3 2 Subunit ChlI of Mg-chelatase Glyco_transf_10 PF00852.19 CBY19385.1 - 1.4e-50 171.5 0.0 2.5e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term DHO_dh PF01180.21 CBY19385.1 - 2.5e-33 115.6 0.0 4.1e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 CBY19385.1 - 5e-32 110.0 0.9 5e-32 110.0 0.9 2.3 3 0 0 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 CBY19385.1 - 2.2e-22 78.9 11.8 2.2e-22 78.9 11.8 3.4 3 0 0 3 3 2 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 CBY19385.1 - 3.4e-13 49.5 0.1 5.7e-12 45.5 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBY19385.1 - 5.3e-08 32.5 0.0 1.9e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 CBY19385.1 - 8.4e-06 26.3 10.5 8.4e-06 26.3 10.5 3.8 4 0 0 4 4 2 2 4Fe-4S dicluster domain NAD_binding_8 PF13450.6 CBY19385.1 - 3.3e-05 24.0 0.0 0.00012 22.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_6 PF12837.7 CBY19385.1 - 3.6e-05 23.7 32.5 0.00021 21.2 2.4 4.4 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 CBY19385.1 - 8.7e-05 22.6 28.7 0.00064 19.8 12.3 3.9 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBY19385.1 - 0.0007 19.5 36.0 0.0032 17.5 3.0 5.1 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4 PF00037.27 CBY19385.1 - 0.0011 18.7 14.8 0.0035 17.1 3.4 4.9 6 0 0 6 6 5 2 4Fe-4S binding domain Pyr_redox PF00070.27 CBY19385.1 - 0.0014 19.1 0.0 1.2 9.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.6 CBY19385.1 - 0.0022 18.1 11.1 0.0022 18.1 11.1 3.1 2 1 1 3 3 3 1 4Fe-4S dicluster domain Glyco_tran_10_N PF17039.5 CBY19385.1 - 0.0027 18.1 0.1 0.0084 16.5 0.1 1.9 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Dus PF01207.17 CBY19385.1 - 0.0075 15.4 0.1 0.035 13.2 0.1 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Shikimate_DH PF01488.20 CBY19385.1 - 0.075 13.1 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Leader_CPA1 PF08252.11 CBY19385.1 - 0.15 11.5 0.5 2.3 7.7 0.0 2.6 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide Fer4_4 PF12800.7 CBY19385.1 - 0.64 10.7 24.7 0.18 12.4 2.8 4.5 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_11 PF13247.6 CBY19385.1 - 2.6 8.2 11.8 19 5.5 5.9 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 CBY19385.1 - 8 7.1 24.8 1.1 9.9 4.7 3.4 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I PDZ_6 PF17820.1 CBY19386.1 - 1.9e-11 43.6 0.0 2.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY19386.1 - 1.4e-07 31.7 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY19386.1 - 5.6e-05 23.4 0.0 8.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain UPF0172 PF03665.13 CBY19387.1 - 6e-47 160.2 0.0 7e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DNA_ligase_IV PF11411.8 CBY19387.1 - 5.3e-05 23.2 0.8 0.00013 22.0 0.2 1.9 2 0 0 2 2 2 1 DNA ligase IV DUF4923 PF16270.5 CBY19387.1 - 0.041 13.7 0.0 5.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Lipocalin-like domain (DUF4923) Arf PF00025.21 CBY19390.1 - 4e-45 153.4 0.2 4.8e-45 153.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBY19390.1 - 7.5e-18 64.6 0.0 8.8e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY19390.1 - 2.3e-16 60.1 0.1 4.4e-16 59.2 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBY19390.1 - 1.7e-09 37.4 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBY19390.1 - 1.3e-08 34.5 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBY19390.1 - 1.9e-08 33.9 0.5 7.2e-06 25.4 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CBY19390.1 - 3.8e-06 27.0 0.1 7e-06 26.1 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CBY19390.1 - 0.005 16.7 0.1 0.14 11.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CBY19390.1 - 0.041 13.8 0.3 0.89 9.4 0.1 2.3 2 1 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 CBY19390.1 - 0.046 13.8 0.1 8.2 6.5 0.1 2.2 1 1 1 2 2 2 0 Dynamin family MOR2-PAG1_N PF14222.6 CBY19391.1 - 4.8e-124 415.3 7.4 1.1e-123 414.1 7.4 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CBY19391.1 - 2.7e-10 40.6 7.4 1e-07 32.1 0.1 4.9 4 0 0 4 4 4 3 Cell morphogenesis C-terminal Pyridoxal_deC PF00282.19 CBY19391.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Dicty_REP PF05086.12 CBY19392.1 - 0.053 11.5 7.5 0.071 11.1 7.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 CBY19392.1 - 1.5 8.8 33.0 3.5 7.6 33.0 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein hEGF PF12661.7 CBY19392.1 - 1.7 9.4 9.2 1.8 9.3 2.9 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 CBY19392.1 - 3.5 8.0 10.6 0.68 10.3 4.1 2.8 2 0 0 2 2 2 0 EGF-like domain Pkinase_Tyr PF07714.17 CBY19393.1 - 4e-86 288.5 0.0 5.4e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY19393.1 - 7.5e-42 143.5 0.0 1.3e-41 142.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 CBY19393.1 - 0.00014 22.4 0.7 2.5 8.7 0.1 3.5 2 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 CBY19393.1 - 0.0011 18.5 0.1 0.0072 15.9 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CBY19393.1 - 0.0023 18.1 2.0 2.9 8.1 0.9 3.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain Haspin_kinase PF12330.8 CBY19393.1 - 0.011 14.7 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBY19393.1 - 0.016 15.1 0.0 0.07 13.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ac76 PF05814.11 CBY19393.1 - 0.024 14.7 0.7 9.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Orf76 (Ac76) Protocadherin PF08374.11 CBY19393.1 - 0.034 14.1 1.4 0.059 13.3 0.1 2.0 2 0 0 2 2 2 0 Protocadherin ig PF00047.25 CBY19393.1 - 0.37 11.0 5.6 20 5.5 2.4 3.4 2 1 0 2 2 2 0 Immunoglobulin domain DUF2237 PF09996.9 CBY19396.1 - 1.7e-38 131.1 0.1 2.1e-38 130.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) DSPc PF00782.20 CBY19397.1 - 2.2e-16 59.9 0.0 1.6e-14 53.9 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CBY19397.1 - 0.00021 21.5 0.0 0.0004 20.7 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 CBY19397.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Zn_Tnp_IS1595 PF12760.7 CBY19397.1 - 0.02 14.8 1.8 9.9 6.2 0.0 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain EMG1 PF03587.14 CBY19398.1 - 1.4e-76 256.5 0.0 1.8e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DDE_3 PF13358.6 CBY19398.1 - 0.054 13.3 0.4 0.12 12.2 0.2 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease ArfGap PF01412.18 CBY19399.1 - 1.3e-22 80.1 0.3 2.6e-22 79.1 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DFRP_C PF16543.5 CBY19400.1 - 9.2e-22 77.4 10.7 9.2e-22 77.4 10.7 3.3 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 INCENP_ARK-bind PF03941.15 CBY19400.1 - 0.0037 17.2 2.9 0.3 11.1 0.1 2.8 2 0 0 2 2 2 2 Inner centromere protein, ARK binding region zf_CCCH_4 PF18345.1 CBY19400.1 - 0.0095 16.0 1.4 0.016 15.2 1.4 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CBY19400.1 - 0.026 15.2 3.2 0.026 15.2 3.2 3.2 3 2 0 3 3 3 0 Torus domain zf-CCCH_4 PF18044.1 CBY19400.1 - 0.041 13.7 1.1 0.073 12.9 1.1 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 CBY19400.1 - 0.12 12.4 1.2 0.18 11.7 1.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CD52 PF15116.6 CBY19400.1 - 3.9 7.6 7.8 2.6 8.2 3.5 2.8 2 0 0 2 2 2 0 CAMPATH-1 antigen Tweety PF04906.13 CBY19401.1 - 1.2e-25 90.1 6.8 1.1e-20 73.7 5.8 2.2 1 1 1 2 2 2 2 Tweety 7tm_1 PF00001.21 CBY19401.1 - 0.023 14.0 3.2 0.042 13.2 1.3 2.3 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF2207 PF09972.9 CBY19401.1 - 0.12 11.1 9.3 0.31 9.7 2.5 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 CBY19401.1 - 0.12 12.0 3.8 2 8.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF4446 PF14584.6 CBY19401.1 - 0.33 10.9 4.7 0.12 12.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF3810 PF12725.7 CBY19401.1 - 0.43 9.9 5.1 0.71 9.2 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Lge1 PF11488.8 CBY19401.1 - 1 9.6 4.1 0.46 10.7 1.2 1.9 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF1772 PF08592.11 CBY19401.1 - 6.8 7.0 7.2 8.9 6.6 0.1 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) TPR_MLP1_2 PF07926.12 CBY19402.1 - 0.0016 18.5 0.3 0.0024 17.9 0.3 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Csm1_N PF18504.1 CBY19402.1 - 0.0077 16.5 0.4 0.019 15.3 0.4 1.6 1 0 0 1 1 1 1 Csm1 N-terminal domain TolA_bind_tri PF16331.5 CBY19402.1 - 0.019 15.0 0.4 0.029 14.4 0.4 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF4140 PF13600.6 CBY19402.1 - 0.028 14.8 1.8 0.047 14.1 1.8 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4349 PF14257.6 CBY19402.1 - 0.03 13.8 1.6 0.054 12.9 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) LUC7 PF03194.15 CBY19402.1 - 0.048 13.3 1.2 0.045 13.4 1.2 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Ax_dynein_light PF10211.9 CBY19402.1 - 0.094 12.7 2.6 0.11 12.4 2.6 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain V_ATPase_I PF01496.19 CBY19402.1 - 0.18 9.7 0.5 0.18 9.7 0.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 7tm_2 PF00002.24 CBY19404.1 - 3.3e-07 29.9 11.7 1.6e-06 27.6 11.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 CBY19405.1 - 1.4e-06 28.6 12.7 1.4e-06 28.6 12.7 3.1 3 0 0 3 3 3 1 Somatomedin B domain TSP_1 PF00090.19 CBY19405.1 - 0.02 15.1 10.1 0.02 15.1 10.1 2.6 2 1 0 2 2 2 0 Thrombospondin type 1 domain Zona_pellucida PF00100.23 CBY19407.1 - 1.3e-26 93.9 0.0 1.9e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Adeno_E3_CR2 PF02439.15 CBY19407.1 - 0.057 13.2 1.1 0.11 12.2 1.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ac76 PF05814.11 CBY19407.1 - 0.18 11.8 1.1 0.34 10.9 1.1 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) EphA2_TM PF14575.6 CBY19407.1 - 0.7 10.8 2.8 1.1 10.2 2.1 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PAP2 PF01569.21 CBY19409.1 - 4.6e-27 94.4 0.0 6.4e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 PAP2 superfamily C2 PF00168.30 CBY19410.1 - 1.8e-09 37.8 0.1 5.2e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 CBY19411.1 - 4e-20 72.0 0.1 5e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MMM1 PF10296.9 CBY19411.1 - 0.0097 15.0 0.7 0.022 13.8 0.7 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 C2 PF00168.30 CBY19412.1 - 1.8e-09 37.8 0.1 5.2e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 CBY19413.1 - 4e-20 72.0 0.1 5e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MMM1 PF10296.9 CBY19413.1 - 0.0097 15.0 0.7 0.022 13.8 0.7 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ANAPC4_WD40 PF12894.7 CBY19414.1 - 8.3e-05 22.8 0.2 0.71 10.2 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 CBY19414.1 - 0.0097 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region TRAP_alpha PF03896.16 CBY19415.1 - 1e-31 110.2 6.2 2.3e-31 109.1 6.2 1.5 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF3493 PF11998.8 CBY19415.1 - 0.16 12.2 2.0 0.43 10.8 2.0 1.7 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 IF4E PF01652.18 CBY19416.1 - 1.2e-48 164.9 0.2 1.7e-48 164.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PRP3 PF08572.10 CBY19416.1 - 0.016 14.9 3.8 0.02 14.7 3.8 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) INCENP_ARK-bind PF03941.15 CBY19419.1 - 8.5e-10 38.4 1.9 1.1e-09 38.1 0.2 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region BLOC1S3 PF15753.5 CBY19419.1 - 1.9 8.6 7.4 2.5 8.2 4.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Ax_dynein_light PF10211.9 CBY19420.1 - 2.6e-06 27.5 5.5 2.6e-06 27.5 5.5 4.1 3 1 0 3 3 3 1 Axonemal dynein light chain DUF4665 PF15679.5 CBY19420.1 - 1.5 9.5 8.1 22 5.8 2.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4665) Atg14 PF10186.9 CBY19421.1 - 0.099 11.7 14.0 0.12 11.4 14.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CBY19421.1 - 0.2 11.2 12.7 0.24 10.9 12.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4554 PF15091.6 CBY19421.1 - 0.53 9.1 8.9 0.62 8.9 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) AAA_11 PF13086.6 CBY19421.1 - 0.88 9.3 13.0 1.3 8.7 13.0 1.3 1 0 0 1 1 1 0 AAA domain Asp-B-Hydro_N PF05279.11 CBY19421.1 - 2.8 8.0 19.3 3.6 7.6 19.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDHD PF02862.17 CBY19421.1 - 3 7.9 8.8 3.9 7.6 8.8 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CBY19421.1 - 3.2 6.4 12.3 3.7 6.2 12.3 1.1 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 CBY19421.1 - 3.3 6.1 25.2 4 5.8 25.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2868 PF11067.8 CBY19421.1 - 4.3 6.8 6.9 6.1 6.3 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CDC45 PF02724.14 CBY19421.1 - 6.8 4.9 18.5 8.6 4.5 18.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Autophagy_N PF03986.13 CBY19421.1 - 6.8 6.6 12.6 12 5.8 12.6 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain AAA_11 PF13086.6 CBY19422.1 - 0.049 13.4 5.8 0.058 13.2 5.8 1.2 1 0 0 1 1 1 0 AAA domain AcetylCoA_hydro PF02550.15 CBY19422.1 - 0.21 11.6 1.6 0.3 11.0 1.6 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain Membralin PF09746.9 CBY19422.1 - 4.5 6.2 6.7 5.5 5.9 6.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4407 PF14362.6 CBY19422.1 - 4.8 6.5 12.3 6.3 6.1 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pneumo_M2 PF07380.11 CBY19423.1 - 0.069 13.4 1.5 0.62 10.4 0.1 2.5 2 0 0 2 2 2 0 Pneumovirus M2 protein FAD-SLDH PF12318.8 CBY19423.1 - 0.32 11.0 5.3 3.1 7.9 0.1 2.7 1 1 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Mito_carr PF00153.27 CBY19424.1 - 1.7e-48 162.5 1.0 2.2e-15 56.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_98C PF08307.11 CBY19424.1 - 0.14 11.6 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain Mito_carr PF00153.27 CBY19426.1 - 5.1e-60 199.4 2.8 1e-19 70.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 CBY19426.1 - 0.14 12.2 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) zf-RING_2 PF13639.6 CBY19427.1 - 1.1e-10 41.7 18.7 1.4e-10 41.3 16.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CBY19427.1 - 5.4e-09 36.2 12.7 5.4e-09 36.2 12.7 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBY19427.1 - 7e-07 28.9 9.9 7e-07 28.9 9.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CBY19427.1 - 9e-06 25.7 7.6 1.7e-05 24.8 7.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CBY19427.1 - 4.9e-05 23.1 16.1 4.9e-05 23.1 16.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY19427.1 - 0.00018 21.3 16.2 0.00018 21.3 16.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY19427.1 - 0.00042 20.2 15.1 0.00042 20.2 15.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY19427.1 - 0.00063 19.5 13.8 0.00063 19.5 13.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBY19427.1 - 0.0017 17.9 12.1 0.0017 17.9 12.1 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type DUF4472 PF14739.6 CBY19427.1 - 0.0021 18.8 6.4 0.0021 18.8 6.4 3.0 4 0 0 4 4 2 1 Domain of unknown function (DUF4472) APG6_N PF17675.1 CBY19427.1 - 0.0023 18.5 6.5 0.0023 18.5 6.5 2.9 3 0 0 3 3 2 1 Apg6 coiled-coil region zf-RING_UBOX PF13445.6 CBY19427.1 - 0.0033 17.4 14.5 0.0033 17.4 14.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger CEP63 PF17045.5 CBY19427.1 - 0.0034 17.3 23.6 0.0071 16.3 23.6 1.5 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa TMF_TATA_bd PF12325.8 CBY19427.1 - 0.0074 16.5 22.1 0.057 13.6 2.7 3.4 3 0 0 3 3 3 2 TATA element modulatory factor 1 TATA binding Sec34 PF04136.15 CBY19427.1 - 0.045 13.6 12.9 0.12 12.3 3.8 2.5 2 0 0 2 2 2 0 Sec34-like family Prok-RING_4 PF14447.6 CBY19427.1 - 0.087 12.7 17.0 0.031 14.1 14.2 1.7 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 XkdW PF09636.10 CBY19427.1 - 0.13 12.4 9.6 2.6 8.2 2.1 2.7 2 0 0 2 2 2 0 XkdW protein RINGv PF12906.7 CBY19427.1 - 0.29 11.3 15.3 0.81 9.9 15.3 1.8 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 CBY19427.1 - 0.38 11.0 12.4 1.5 9.0 12.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CBY19427.1 - 0.41 10.5 13.5 1 9.2 13.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lectin_N PF03954.14 CBY19427.1 - 0.55 10.0 10.4 0.21 11.4 3.7 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF724 PF05266.14 CBY19427.1 - 0.67 9.7 21.3 0.43 10.4 10.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Prok-RING_1 PF14446.6 CBY19427.1 - 0.7 9.9 14.8 2.7 8.0 14.8 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Seryl_tRNA_N PF02403.22 CBY19427.1 - 0.73 10.1 29.0 1.7 8.9 13.9 3.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 CBY19427.1 - 1.7 7.9 28.9 0.71 9.2 13.1 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TerY_C PF15616.6 CBY19427.1 - 2.7 8.1 7.6 7.9 6.6 7.6 1.7 1 0 0 1 1 1 0 TerY-C metal binding domain Baculo_IE-1 PF05290.11 CBY19427.1 - 2.8 7.9 14.0 0.18 11.8 7.8 2.1 2 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) Golgin_A5 PF09787.9 CBY19427.1 - 8.2 5.8 28.0 11 5.4 11.0 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 SURF4 PF02077.15 CBY19428.1 - 6.6e-73 245.6 8.0 8e-72 242.0 8.0 1.9 1 1 0 1 1 1 1 SURF4 family DoxX PF07681.12 CBY19428.1 - 0.00013 22.4 0.2 0.00013 22.4 0.2 3.4 3 1 0 3 3 3 1 DoxX HR_lesion PF05514.11 CBY19428.1 - 0.073 13.2 11.0 0.047 13.9 2.3 2.9 2 2 0 2 2 2 0 HR-like lesion-inducing Microcin PF03526.13 CBY19428.1 - 0.52 10.2 0.1 0.52 10.2 0.1 2.0 2 1 0 2 2 2 0 Colicin E1 (microcin) immunity protein DUF2101 PF09874.9 CBY19428.1 - 1.3 8.7 10.2 0.21 11.2 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) TMF_TATA_bd PF12325.8 CBY19429.1 - 5.7e-25 87.8 7.9 5.7e-25 87.8 7.9 8.0 2 1 3 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CBY19429.1 - 5.9e-15 55.0 11.1 5.9e-15 55.0 11.1 10.0 5 3 3 8 8 8 3 TATA element modulatory factor 1 DNA binding Filament PF00038.21 CBY19429.1 - 0.00045 19.9 50.6 0.00045 19.9 50.6 4.1 2 1 1 3 3 3 2 Intermediate filament protein CHASE3 PF05227.13 CBY19429.1 - 0.0037 17.2 10.7 0.0037 17.2 10.7 6.5 3 3 3 7 7 7 3 CHASE3 domain Rab5-bind PF09311.11 CBY19429.1 - 0.0053 16.2 31.2 0.0053 16.2 31.2 4.4 2 1 2 4 4 4 1 Rabaptin-like protein CODH_A_N PF18537.1 CBY19429.1 - 0.035 14.1 0.4 0.46 10.5 0.1 3.1 2 1 1 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Spc7 PF08317.11 CBY19429.1 - 0.84 8.5 99.7 0.08 11.8 6.5 5.5 2 1 3 5 5 5 0 Spc7 kinetochore protein Pkinase PF00069.25 CBY19430.1 - 1.7e-63 214.5 0.0 2.5e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19430.1 - 1.6e-39 135.8 0.0 2.3e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CNH PF00780.22 CBY19430.1 - 1.1e-36 126.8 0.0 1.7e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase_fungal PF17667.1 CBY19430.1 - 0.00044 19.1 0.0 0.0009 18.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY19430.1 - 0.001 18.4 0.0 0.0024 17.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like SidC_N PF18219.1 CBY19431.1 - 0.0053 15.8 0.1 0.0068 15.4 0.1 1.1 1 0 0 1 1 1 1 SidC N-terminal domain Rubella_Capsid PF05750.11 CBY19431.1 - 0.21 11.2 2.2 0.33 10.5 2.2 1.3 1 0 0 1 1 1 0 Rubella capsid protein CUE PF02845.16 CBY19432.1 - 1.5e-13 50.2 0.1 3.3e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 CUE domain C2 PF00168.30 CBY19432.1 - 3.7e-13 49.7 0.0 6.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain Cupin_8 PF13621.6 CBY19433.1 - 7.7e-29 101.2 0.0 1.1e-28 100.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY19433.1 - 1e-05 25.2 0.0 2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 CBY19433.1 - 0.021 15.3 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 CBY19433.1 - 0.031 14.0 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Cupin domain DZF PF07528.14 CBY19434.1 - 1.3e-71 241.1 0.0 2.5e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 DZF domain RRM_1 PF00076.22 CBY19435.1 - 3.1e-28 97.4 0.0 2.2e-15 56.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY19435.1 - 2.8e-12 46.6 0.0 5.3e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CBY19435.1 - 0.0046 17.0 0.1 0.074 13.1 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif CH PF00307.31 CBY19436.1 - 2.6e-76 252.9 0.1 2.9e-23 82.1 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_6 PF13405.6 CBY19436.1 - 3.8e-07 29.5 0.4 2.4e-05 23.9 0.2 3.0 1 1 1 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CBY19436.1 - 4.2e-06 27.1 0.1 2.2e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY19436.1 - 2.2e-05 23.7 0.2 9.9e-05 21.6 0.2 2.2 1 0 0 1 1 1 1 EF hand CAMSAP_CH PF11971.8 CBY19436.1 - 2.4e-05 24.1 0.0 0.015 15.1 0.0 3.4 4 0 0 4 4 4 1 CAMSAP CH domain CH_2 PF06294.11 CBY19436.1 - 0.0002 21.4 0.0 0.33 11.1 0.0 3.8 4 0 0 4 4 4 1 CH-like domain in sperm protein EF-hand_5 PF13202.6 CBY19436.1 - 0.0043 16.5 0.2 0.012 15.0 0.2 1.8 1 0 0 1 1 1 1 EF hand Claudin_2 PF13903.6 CBY19438.1 - 9.3e-08 32.0 13.0 9.3e-08 32.0 13.0 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CBY19438.1 - 0.0011 18.8 14.5 0.0025 17.7 14.5 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Trp_oprn_chp PF09534.10 CBY19438.1 - 0.0054 16.5 1.8 0.0088 15.9 1.2 1.6 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4064 PF13273.6 CBY19438.1 - 0.019 15.2 9.2 0.24 11.7 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF5362 PF17319.2 CBY19438.1 - 0.028 14.2 0.7 0.028 14.2 0.7 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5362) DUF872 PF05915.12 CBY19438.1 - 7.1 6.8 9.0 1.1 9.5 0.4 2.8 2 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) ER_lumen_recept PF00810.18 CBY19439.1 - 3.2e-52 177.3 9.9 5.6e-52 176.5 9.9 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CBY19439.1 - 0.015 15.0 7.0 0.5 10.2 0.7 3.1 2 1 1 3 3 3 0 PQ loop repeat EGF PF00008.27 CBY19440.1 - 6.4e-13 48.7 111.0 1.6e-05 25.1 7.7 9.0 8 0 0 8 8 8 6 EGF-like domain EGF_2 PF07974.13 CBY19440.1 - 7.2e-08 32.7 136.3 0.0033 17.8 12.9 9.3 8 1 0 8 8 8 6 EGF-like domain hEGF PF12661.7 CBY19440.1 - 0.00025 21.5 98.3 0.025 15.2 5.9 9.5 8 0 0 8 8 8 5 Human growth factor-like EGF EGF_Tenascin PF18720.1 CBY19440.1 - 0.53 10.4 44.0 0.47 10.5 4.5 6.5 5 0 0 5 5 5 0 Tenascin EGF domain DivIC PF04977.15 CBY19441.1 - 0.00075 19.2 0.6 0.0012 18.6 0.6 1.4 1 0 0 1 1 1 1 Septum formation initiator NRBF2 PF08961.10 CBY19441.1 - 0.00086 19.0 1.6 0.00097 18.8 1.1 1.3 1 1 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 CBY19441.1 - 0.0016 18.6 0.2 0.0045 17.2 0.2 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper HIP1_clath_bdg PF16515.5 CBY19441.1 - 0.015 15.9 2.6 0.015 15.9 2.6 1.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KLRAQ PF10205.9 CBY19441.1 - 0.036 14.3 1.5 0.048 13.9 1.5 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein SlyX PF04102.12 CBY19441.1 - 0.067 13.8 1.1 0.14 12.8 1.1 1.7 1 1 0 1 1 1 0 SlyX DUF5499 PF17603.2 CBY19441.1 - 0.074 13.7 0.0 0.089 13.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5499) PIN_10 PF18478.1 CBY19441.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 PIN like domain Cwf_Cwc_15 PF04889.12 CBY19442.1 - 0.99 9.1 14.1 1.2 8.8 13.9 1.2 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PepSY_TM_like_2 PF16357.5 CBY19442.1 - 2.3 8.1 4.0 2.9 7.8 4.0 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like Sec62 PF03839.16 CBY19442.1 - 5.2 6.5 6.9 5.4 6.5 6.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 zf-C2H2 PF00096.26 CBY19443.1 - 1.4e-08 34.7 18.2 4.1e-05 23.8 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY19443.1 - 6.7e-08 32.6 2.9 6.7e-08 32.6 2.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY19443.1 - 0.00015 22.3 18.3 0.064 14.1 1.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY19443.1 - 0.0057 16.4 7.6 0.12 12.1 3.9 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type DUF3072 PF11272.8 CBY19443.1 - 0.072 13.0 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) zf-C2H2_jaz PF12171.8 CBY19443.1 - 0.11 12.8 1.0 0.11 12.8 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CRM1_C PF08767.11 CBY19444.1 - 8.6e-120 399.7 9.9 8.7e-120 399.7 3.9 3.4 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CBY19444.1 - 3.9e-36 124.4 6.0 3.9e-36 124.4 6.0 4.8 5 1 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CBY19444.1 - 3.5e-35 119.5 2.7 3.5e-35 119.5 2.7 2.5 3 0 0 3 3 3 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CBY19444.1 - 1.4e-28 98.8 1.6 3e-28 97.7 0.4 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CBY19444.1 - 2e-17 62.4 0.7 2e-17 62.4 0.7 2.3 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CBY19444.1 - 7.8e-13 48.1 0.2 7.8e-13 48.1 0.2 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain HECW_N PF16562.5 CBY19444.1 - 0.028 14.2 0.1 0.56 10.0 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 YscO PF07321.12 CBY19444.1 - 0.18 11.8 2.2 0.22 11.4 0.1 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO Ank_2 PF12796.7 CBY19445.1 - 3.4e-08 34.0 0.0 6.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY19445.1 - 1.1e-05 25.7 0.2 0.023 15.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CBY19445.1 - 1.1e-05 25.4 0.0 0.13 12.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CBY19445.1 - 2e-05 25.0 0.1 4.1e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY19445.1 - 0.0063 16.8 0.1 0.38 11.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF4064 PF13273.6 CBY19445.1 - 0.26 11.6 0.0 0.26 11.6 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Sulfotransfer_1 PF00685.27 CBY19446.1 - 6.2e-12 45.6 0.5 2.1e-11 43.9 0.5 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY19446.1 - 2e-11 44.7 0.0 0.00056 20.3 0.0 3.2 2 1 1 3 3 3 3 Sulfotransferase family Sulfotransfer_4 PF17784.1 CBY19446.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase domain Laminin_I PF06008.14 CBY19446.1 - 0.041 13.6 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain I DUF2183 PF09949.9 CBY19446.1 - 0.099 13.0 0.1 0.44 10.9 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2183) Gpi16 PF04113.14 CBY19447.1 - 2.3e-74 250.9 0.0 5.7e-37 127.4 0.0 2.0 1 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component Sulfotransfer_2 PF03567.14 CBY19448.1 - 6.9e-37 127.7 1.2 9.5e-37 127.3 1.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family PMC2NT PF08066.12 CBY19449.1 - 0.025 15.2 0.1 0.26 12.0 0.0 2.4 2 1 1 3 3 3 0 PMC2NT (NUC016) domain UPF0184 PF03670.13 CBY19449.1 - 0.11 12.9 0.3 0.23 11.8 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Ribosomal_L7Ae PF01248.26 CBY19450.1 - 1.2e-15 57.0 0.0 2.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GH97_N PF14508.6 CBY19453.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal PI3_PI4_kinase PF00454.27 CBY19454.1 - 7.6e-47 160.2 0.0 7.8e-32 111.1 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CBY19454.1 - 0.0015 17.9 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) DUF3899 PF13038.6 CBY19455.1 - 0.0084 16.6 0.8 0.016 15.7 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3899) DAD PF02109.16 CBY19455.1 - 0.041 14.2 0.2 0.056 13.8 0.2 1.3 1 0 0 1 1 1 0 DAD family GH97_N PF14508.6 CBY19457.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal PI3_PI4_kinase PF00454.27 CBY19458.1 - 6.2e-46 157.2 0.0 2.2e-31 109.6 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CBY19458.1 - 1.9e-35 122.0 0.1 3.2e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CBY19458.1 - 6.5e-18 65.0 0.0 1.2e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CBY19458.1 - 0.0051 16.2 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) JmjC PF02373.22 CBY19461.1 - 7.4e-22 77.9 0.3 1.6e-21 76.9 0.3 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CBY19461.1 - 9.1e-17 61.6 0.5 1.9e-16 60.6 0.5 1.5 1 0 0 1 1 1 1 Cupin-like domain AF-4 PF05110.13 CBY19461.1 - 2.5 6.1 18.9 3.4 5.6 18.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RRM_1 PF00076.22 CBY19462.1 - 3.1e-16 59.0 0.3 5e-16 58.3 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY19462.1 - 0.00012 21.6 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY19462.1 - 0.00072 19.6 0.1 0.0015 18.5 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif Ribosomal_S11 PF00411.19 CBY19463.1 - 5.3e-45 152.3 0.7 6.6e-45 152.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 CBY19463.1 - 0.063 13.5 0.0 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) 7tm_1 PF00001.21 CBY19465.1 - 1.8e-07 30.8 4.1 1e-05 25.0 4.1 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_A14 PF05767.12 CBY19465.1 - 0.52 10.5 3.6 0.41 10.8 0.5 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Aldedh PF00171.22 CBY19466.1 - 4.6e-10 38.6 0.8 5.6e-10 38.3 0.8 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FXa_inhibition PF14670.6 CBY19467.1 - 0.0054 17.0 10.3 0.043 14.1 10.3 2.7 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site DUF3439 PF11921.8 CBY19467.1 - 0.024 14.6 2.5 0.094 12.7 2.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSF PF00474.17 CBY19468.1 - 3.6e-19 68.9 27.9 5.8e-17 61.6 28.0 2.6 1 1 1 2 2 2 2 Sodium:solute symporter family NnrU PF07298.11 CBY19468.1 - 0.011 15.2 2.3 0.12 11.9 3.5 2.1 2 0 0 2 2 2 0 NnrU protein Mito_morph_reg PF14972.6 CBY19468.1 - 0.14 11.8 1.8 0.31 10.6 1.8 1.5 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator fn3 PF00041.21 CBY19469.1 - 8.5e-10 38.8 10.6 0.023 15.0 0.0 7.8 10 0 0 10 10 10 3 Fibronectin type III domain Ldl_recept_a PF00057.18 CBY19469.1 - 1.1e-07 32.0 11.2 1.1e-07 32.0 11.2 3.9 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A DUF2369 PF10179.9 CBY19469.1 - 0.092 13.1 0.2 0.64 10.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) DUF5305 PF17231.2 CBY19471.1 - 0.025 14.0 0.7 0.034 13.5 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) COesterase PF00135.28 CBY19472.1 - 4.2e-10 39.1 0.1 4.6e-10 39.0 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family AAA_5 PF07728.14 CBY19472.1 - 0.012 15.6 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF983 PF06170.12 CBY19473.1 - 0.11 13.0 0.5 0.11 13.0 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF983) DUF2157 PF09925.9 CBY19473.1 - 0.16 11.8 5.6 0.35 10.7 5.2 1.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4199 PF13858.6 CBY19473.1 - 0.74 10.2 12.1 0.06 13.7 6.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) DUF3810 PF12725.7 CBY19473.1 - 1.8 7.8 3.4 2.6 7.3 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF5381 PF17353.2 CBY19473.1 - 2.3 7.9 10.2 0.088 12.6 2.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Vma12 PF11712.8 CBY19473.1 - 5.3 7.1 5.6 1.2 9.2 1.6 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2207 PF09972.9 CBY19473.1 - 8.2 5.1 10.1 2.3e+02 0.3 10.1 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) V-ATPase_G PF03179.15 CBY19474.1 - 3.7e-27 94.9 17.4 4.1e-27 94.8 17.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3828 PF12883.7 CBY19474.1 - 0.046 14.1 2.0 0.067 13.6 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) Inhibitor_I71 PF12628.7 CBY19474.1 - 0.058 13.2 0.8 0.076 12.9 0.8 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor OmpH PF03938.14 CBY19474.1 - 0.085 13.2 14.7 0.11 12.8 14.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FdhE PF04216.12 CBY19474.1 - 0.26 11.1 2.7 0.31 10.9 2.7 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DDE_Tnp_ISAZ013 PF07592.11 CBY19474.1 - 0.32 10.0 3.4 0.33 9.9 3.4 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DUF1690 PF07956.11 CBY19474.1 - 0.38 11.2 10.3 0.62 10.5 10.3 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Atg14 PF10186.9 CBY19474.1 - 0.51 9.4 8.3 0.61 9.1 8.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CBY19474.1 - 0.68 9.2 8.6 0.97 8.7 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_22 PF18833.1 CBY19474.1 - 0.73 10.0 6.1 0.47 10.6 0.5 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat LprI PF07007.12 CBY19474.1 - 0.77 10.5 5.3 1.2 9.8 4.7 1.6 1 1 1 2 2 2 0 Lysozyme inhibitor LprI DUF16 PF01519.16 CBY19474.1 - 0.9 10.1 11.5 0.29 11.6 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 eIF3_N PF09440.10 CBY19474.1 - 0.93 9.9 7.4 0.98 9.9 6.2 1.6 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain RAI1 PF08652.11 CBY19474.1 - 0.98 9.7 3.6 1.4 9.2 3.6 1.4 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease RRF PF01765.19 CBY19474.1 - 1.7 8.6 15.9 1.3 9.0 14.7 1.4 1 1 0 1 1 1 0 Ribosome recycling factor HIP1_clath_bdg PF16515.5 CBY19474.1 - 2.4 8.8 12.3 6.1 7.5 10.7 1.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V-ATPase_G_2 PF16999.5 CBY19474.1 - 3.5 8.1 14.7 15 6.1 14.7 1.8 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit HSCB_C PF07743.13 CBY19474.1 - 5.2 7.6 10.9 2 9.0 0.3 2.4 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain ATP-synt_B PF00430.18 CBY19474.1 - 7.4 6.7 18.8 62 3.7 18.8 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) I-set PF07679.16 CBY19475.1 - 4.4e-80 263.9 8.3 2.8e-16 59.3 0.0 7.7 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY19475.1 - 1.5e-46 156.9 0.2 3.5e-09 37.1 0.0 7.4 7 0 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.21 CBY19475.1 - 1.9e-33 114.6 0.0 1.8e-12 47.4 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.25 CBY19475.1 - 3.8e-21 75.1 0.5 0.00028 21.0 0.0 7.2 7 0 0 7 7 7 4 Immunoglobulin domain Ig_2 PF13895.6 CBY19475.1 - 7.9e-19 67.8 0.3 0.0014 18.9 0.0 7.0 7 0 0 7 7 7 4 Immunoglobulin domain V-set PF07686.17 CBY19475.1 - 1.1e-17 64.1 4.5 0.11 12.7 0.0 9.6 7 4 2 9 9 9 3 Immunoglobulin V-set domain THB PF18362.1 CBY19475.1 - 7.3e-11 41.5 0.3 2.4e-10 39.8 0.1 2.0 1 1 1 2 2 2 1 Tri-helix bundle domain Receptor_2B4 PF11465.8 CBY19475.1 - 2.6e-08 34.0 0.3 0.028 14.6 0.0 5.2 5 1 0 5 5 5 2 Natural killer cell receptor 2B4 Herpes_gI PF01688.17 CBY19475.1 - 1.4e-05 25.1 0.2 0.5 10.3 0.0 3.9 4 0 0 4 4 3 1 Alphaherpesvirus glycoprotein I Pur_ac_phosph_N PF16656.5 CBY19475.1 - 0.00047 20.7 0.0 0.43 11.2 0.0 4.1 3 1 1 4 4 3 1 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 CBY19475.1 - 0.00051 19.5 0.0 4.1 7.0 0.0 4.4 5 0 0 5 5 5 1 Immunoglobulin domain C2-set_2 PF08205.12 CBY19475.1 - 0.0014 18.7 0.1 4 7.6 0.0 4.3 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 CBY19475.1 - 0.047 14.1 4.0 72 3.9 0.1 4.6 5 0 0 5 5 5 0 Immunoglobulin C1-set domain MG2 PF01835.19 CBY19475.1 - 0.052 14.0 0.0 51 4.4 0.0 4.2 4 0 0 4 4 4 0 MG2 domain LPD3 PF18798.1 CBY19475.1 - 0.067 13.4 0.1 22 5.3 0.0 2.9 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 3 MBG_2 PF18676.1 CBY19475.1 - 0.1 13.2 0.0 15 6.3 0.0 3.9 3 0 0 3 3 3 0 MBG domain (YGX type) fn3 PF00041.21 CBY19476.1 - 5.8e-20 71.4 0.2 2.4e-11 43.8 0.2 2.8 2 0 0 2 2 2 2 Fibronectin type III domain I-set PF07679.16 CBY19476.1 - 5.3e-16 58.5 0.0 2.5e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY19476.1 - 4.7e-11 43.1 0.0 0.00032 21.2 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CBY19476.1 - 2e-08 34.3 0.0 8.4e-05 22.7 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain zf-H2C2_2 PF13465.6 CBY19476.1 - 2.4e-08 34.0 16.0 2.8e-08 33.8 1.7 3.0 2 0 0 2 2 2 1 Zinc-finger double domain V-set PF07686.17 CBY19476.1 - 4.9e-06 26.7 0.0 0.029 14.5 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 CBY19476.1 - 8.8e-06 26.0 0.4 0.038 14.3 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain zf-C2H2 PF00096.26 CBY19476.1 - 0.032 14.7 0.3 0.032 14.7 0.3 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Ion_trans_2 PF07885.16 CBY19477.1 - 1.8e-30 104.7 15.0 4.5e-16 58.6 1.6 3.3 3 0 0 3 3 3 3 Ion channel I-set PF07679.16 CBY19477.1 - 8e-16 57.9 0.0 2.1e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY19477.1 - 8.7e-11 42.3 0.0 1.9e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY19477.1 - 2e-08 34.3 0.0 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY19477.1 - 3.5e-07 30.5 0.0 8.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ion_trans PF00520.31 CBY19477.1 - 0.0023 17.2 5.7 0.0039 16.4 0.5 2.8 3 0 0 3 3 3 1 Ion transport protein V-set PF07686.17 CBY19477.1 - 0.0054 16.9 0.0 0.041 14.1 0.0 2.2 1 1 1 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 CBY19477.1 - 0.024 15.0 0.0 0.071 13.5 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin C1-set domain IRK PF01007.20 CBY19477.1 - 0.039 13.8 3.7 1.1 9.0 0.1 3.0 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY19478.1 - 6.2e-32 109.4 18.7 2.7e-16 59.3 1.6 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CBY19478.1 - 0.0024 17.2 0.5 0.0024 17.2 0.5 2.5 2 1 0 2 2 2 2 Ion transport protein IRK PF01007.20 CBY19478.1 - 0.2 11.4 5.2 0.7 9.7 0.1 3.0 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Halogen_Hydrol PF10112.9 CBY19479.1 - 0.0035 17.4 3.0 0.036 14.1 0.0 2.6 3 0 0 3 3 3 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF1326 PF07040.11 CBY19479.1 - 0.044 13.8 0.5 0.083 12.9 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1326) Kri1 PF05178.12 CBY19479.1 - 0.11 13.1 3.7 0.33 11.5 3.7 1.8 1 0 0 1 1 1 0 KRI1-like family Trypsin PF00089.26 CBY19480.1 - 9.8e-73 244.6 9.3 5.7e-42 144.0 0.0 4.5 4 0 0 4 4 3 3 Trypsin Trypsin_2 PF13365.6 CBY19480.1 - 4.1e-06 27.7 0.0 0.026 15.4 0.0 2.9 2 0 0 2 2 2 2 Trypsin-like peptidase domain CUB PF00431.20 CBY19480.1 - 6.9e-05 23.2 1.3 0.00027 21.3 0.2 2.4 2 0 0 2 2 2 1 CUB domain SR-25 PF10500.9 CBY19480.1 - 0.0018 17.9 11.8 0.0035 17.0 11.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1986 PF09342.11 CBY19480.1 - 0.0018 18.6 2.0 3 8.3 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1986) NAM-associated PF14303.6 CBY19480.1 - 0.0052 17.5 9.8 0.013 16.3 9.8 1.6 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Mucin PF01456.17 CBY19480.1 - 0.0054 16.7 50.8 0.01 15.8 50.8 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Med3 PF11593.8 CBY19480.1 - 0.0087 15.3 24.9 0.014 14.6 24.9 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DDHD PF02862.17 CBY19480.1 - 0.35 11.0 4.1 0.71 10.0 4.1 1.4 1 0 0 1 1 1 0 DDHD domain Ndc1_Nup PF09531.10 CBY19480.1 - 0.43 9.2 6.0 0.63 8.7 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AP3D1 PF06375.11 CBY19480.1 - 0.84 9.9 8.0 1.8 8.7 8.0 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 SprA-related PF12118.8 CBY19480.1 - 1.7 7.7 14.1 2.9 7.0 14.1 1.2 1 0 0 1 1 1 0 SprA-related family Peptidase_S49_N PF08496.10 CBY19480.1 - 1.7 8.7 6.1 4 7.5 6.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.8 CBY19480.1 - 2.4 7.0 7.6 4.2 6.2 7.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC27 PF09507.10 CBY19480.1 - 7.3 5.9 24.8 3.3 7.0 18.7 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 AJAP1_PANP_C PF15298.6 CBY19480.1 - 9 6.5 28.6 22 5.2 28.6 1.7 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Tetraspanin PF00335.20 CBY19481.1 - 4.7e-51 173.7 8.3 5.4e-51 173.5 8.3 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2417 PF10329.9 CBY19481.1 - 4.5 6.6 9.9 6.6 6.1 9.9 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Atg8 PF02991.16 CBY19482.1 - 1.2e-27 96.1 0.0 1.4e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBY19482.1 - 1.1e-07 32.1 0.0 1.4e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 bZIP_1 PF00170.21 CBY19483.1 - 5.7e-09 35.9 14.8 1.1e-08 35.0 14.4 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CBY19483.1 - 4e-06 27.2 10.7 8.4e-06 26.2 10.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CBY19483.1 - 1.2e-05 25.3 12.8 6.4e-05 23.0 12.3 2.3 1 1 1 2 2 2 1 Basic region leucine zipper Cas_Csn2 PF09711.10 CBY19483.1 - 0.025 14.3 3.7 0.53 9.9 0.9 2.3 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csn2) Trypsin PF00089.26 CBY19484.1 - 1.9e-38 132.5 0.4 7.6e-31 107.6 0.2 2.2 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CBY19484.1 - 0.0098 16.8 0.0 0.015 16.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY19484.1 - 0.037 13.6 0.0 0.27 10.8 0.0 2.2 2 1 0 2 2 2 0 Chymotrypsin family Peptidase-S1 DUF3439 PF11921.8 CBY19484.1 - 0.15 12.0 7.5 0.3 11.1 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Trypsin PF00089.26 CBY19485.1 - 3.3e-254 838.0 51.2 1.6e-54 185.0 0.1 9.6 7 3 2 9 9 9 8 Trypsin TSP_1 PF00090.19 CBY19485.1 - 1.5e-11 44.4 23.3 3.5e-08 33.5 1.5 3.8 3 0 0 3 3 3 2 Thrombospondin type 1 domain DUF1986 PF09342.11 CBY19485.1 - 0.0012 19.3 16.2 0.063 13.7 0.4 5.6 5 1 0 5 5 5 3 Domain of unknown function (DUF1986) Peptidase_M14 PF00246.24 CBY19486.1 - 7.7e-08 32.5 0.2 3.8e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 CBY19486.1 - 0.00016 21.8 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 CBY19486.1 - 0.18 11.9 0.1 0.49 10.4 0.1 1.8 1 1 0 1 1 1 0 CarboxypepD_reg-like domain MAM PF00629.23 CBY19488.1 - 2.2e-105 349.5 2.1 1.2e-25 90.3 0.0 8.2 6 3 0 6 6 6 6 MAM domain, meprin/A5/mu Astacin PF01400.24 CBY19488.1 - 2.5e-49 167.5 0.0 5.2e-49 166.5 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) fn3 PF00041.21 CBY19488.1 - 4.1e-27 94.4 28.3 2.2e-05 24.7 0.2 13.7 12 3 2 14 14 13 6 Fibronectin type III domain CUB PF00431.20 CBY19488.1 - 2.2e-15 57.0 0.1 6.8e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.19 CBY19488.1 - 2e-09 37.5 9.0 5.1e-09 36.2 9.0 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain Pur_ac_phosph_N PF16656.5 CBY19488.1 - 0.001 19.6 12.7 2 9.0 0.8 7.8 6 2 0 6 6 6 1 Purple acid Phosphatase, N-terminal domain DUF4992 PF16383.5 CBY19488.1 - 0.0019 17.8 1.8 0.0019 17.8 1.8 4.3 5 1 1 6 6 6 1 Domain of unknown function CBM_4_9 PF02018.17 CBY19488.1 - 0.14 12.4 6.7 13 6.0 0.1 5.7 4 1 1 5 5 5 0 Carbohydrate binding domain MORN PF02493.20 CBY19489.1 - 7.3e-37 123.1 36.5 2.2e-06 27.2 1.4 7.5 7 0 0 7 7 7 7 MORN repeat Cbl_N3 PF02762.14 CBY19489.1 - 0.69 9.8 4.8 11 6.0 0.0 3.8 1 1 3 4 4 4 0 CBL proto-oncogene N-terminus, SH2-like domain dCMP_cyt_deam_1 PF00383.23 CBY19491.1 - 4.9e-12 45.6 0.1 9.9e-12 44.6 0.1 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBY19491.1 - 1.4e-06 28.5 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region zf-LITAF-like PF10601.9 CBY19491.1 - 0.018 15.3 1.5 0.028 14.7 1.5 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Suf PF05843.14 CBY19492.1 - 2.3 8.1 7.4 3.1 7.7 7.4 1.3 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) XTBD PF11952.8 CBY19494.1 - 1.2e-16 60.3 0.1 2.3e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD LcrG PF07216.12 CBY19494.1 - 0.011 15.6 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 0 LcrG protein RETICULATA-like PF11891.8 CBY19494.1 - 0.12 12.2 0.0 4.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein RETICULATA-related Pterin_4a PF01329.19 CBY19497.1 - 7.5e-28 96.5 0.0 8.5e-28 96.4 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Spectrin PF00435.21 CBY19498.1 - 0.00027 21.4 10.3 0.00027 21.4 10.3 2.3 1 1 1 2 2 2 1 Spectrin repeat Myb_DNA-bind_3 PF12776.7 CBY19498.1 - 0.13 13.2 3.8 0.23 12.5 3.3 1.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain NTNH_C PF08470.10 CBY19498.1 - 0.18 11.7 2.5 0.24 11.3 1.0 1.8 1 1 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal Sas10_Utp3 PF04000.15 CBY19498.1 - 0.32 11.6 0.3 0.32 11.6 0.3 2.8 3 0 0 3 3 3 0 Sas10/Utp3/C1D family FUSC PF04632.12 CBY19498.1 - 0.34 9.4 1.8 0.4 9.2 1.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlaC_arch PF05377.11 CBY19498.1 - 0.48 10.9 12.6 1.6 9.1 3.7 4.0 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) PA26 PF04636.13 CBY19498.1 - 0.56 9.1 6.8 0.69 8.8 6.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SPACA9 PF15120.6 CBY19498.1 - 0.57 10.0 7.7 1.9 8.3 7.7 1.8 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 Jnk-SapK_ap_N PF09744.9 CBY19498.1 - 1.2 9.3 23.1 2.8 8.1 4.2 2.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 CBY19498.1 - 1.7 8.7 20.9 1.4 9.0 18.9 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CBY19498.1 - 1.8 8.1 10.0 2.2 7.8 10.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ead_Ea22 PF13935.6 CBY19498.1 - 5 7.8 15.0 2.2e+02 2.5 15.1 2.3 1 1 0 1 1 1 0 Ead/Ea22-like protein Hox9_act PF04617.13 CBY19498.1 - 7.3 7.3 8.9 0.51 11.1 2.7 1.8 1 1 1 2 2 2 0 Hox9 activation region FapA PF03961.13 CBY19498.1 - 9 4.8 16.8 17 3.8 16.9 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF2207 PF09972.9 CBY19498.1 - 9.6 4.8 8.3 11 4.7 8.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pterin_4a PF01329.19 CBY19499.1 - 1.4e-18 66.8 0.0 1.6e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Spectrin PF00435.21 CBY19501.1 - 0.00081 19.8 10.2 0.00081 19.8 10.2 2.3 1 1 1 2 2 2 1 Spectrin repeat Atg14 PF10186.9 CBY19501.1 - 0.088 11.9 13.4 0.14 11.2 13.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Myb_DNA-bind_3 PF12776.7 CBY19501.1 - 0.15 13.1 4.4 0.25 12.3 3.1 1.9 1 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain FapA PF03961.13 CBY19501.1 - 0.16 10.6 12.5 0.21 10.2 12.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sas10_Utp3 PF04000.15 CBY19501.1 - 0.26 11.9 0.3 0.26 11.9 0.3 3.0 3 0 0 3 3 3 0 Sas10/Utp3/C1D family Exonuc_VII_L PF02601.15 CBY19501.1 - 0.43 10.1 7.8 0.53 9.8 7.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 CBY19501.1 - 0.99 9.8 12.1 0.47 10.9 2.3 3.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) NTNH_C PF08470.10 CBY19501.1 - 1.1 9.1 4.9 1.3 8.8 1.6 2.3 1 1 2 3 3 3 0 Nontoxic nonhaemagglutinin C-terminal MCC-bdg_PDZ PF10506.9 CBY19501.1 - 2.2 8.4 11.5 25 5.0 5.7 4.0 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Jnk-SapK_ap_N PF09744.9 CBY19501.1 - 2.6 8.2 25.8 0.61 10.3 2.8 2.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 CBY19501.1 - 3.1 6.2 4.7 2.5 6.5 3.3 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Ead_Ea22 PF13935.6 CBY19501.1 - 3.9 8.1 16.7 2e+02 2.6 16.7 2.3 1 1 0 1 1 1 0 Ead/Ea22-like protein UPF0242 PF06785.11 CBY19501.1 - 4.5 7.3 22.8 1.1 9.4 18.6 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 CBY19501.1 - 6.8 4.5 9.4 7.5 4.3 9.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PH_TFIIH PF08567.11 CBY19502.1 - 0.14 12.5 0.3 0.85 10.0 0.0 2.5 2 1 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain RBD-FIP PF09457.10 CBY19502.1 - 0.23 11.4 2.3 0.28 11.1 0.6 2.1 2 0 0 2 2 2 0 FIP domain Tipalpha PF16753.5 CBY19503.1 - 0.093 12.6 0.3 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter Rubis-subs-bind PF09273.11 CBY19504.1 - 0.0079 16.9 0.1 0.02 15.6 0.1 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding DUF4364 PF14277.6 CBY19504.1 - 0.077 12.7 0.1 20 4.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4364) SpoU_methylase PF00588.19 CBY19505.1 - 5.6e-08 33.1 0.0 1.4e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 SpoU rRNA Methylase family Ank_4 PF13637.6 CBY19506.1 - 5.6e-11 42.7 0.5 6.3e-10 39.4 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY19506.1 - 6e-09 36.4 0.1 1.1e-08 35.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY19506.1 - 2.2e-07 30.6 0.3 0.0048 17.3 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CBY19506.1 - 0.00043 20.5 2.0 0.005 17.1 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY19506.1 - 0.0082 16.6 3.0 1.7 9.2 0.4 2.6 2 0 0 2 2 2 2 Ankyrin repeat DUF4507 PF14964.6 CBY19507.1 - 5.2e-18 65.1 0.5 1.2e-17 63.9 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4507) Aim21 PF11489.8 CBY19507.1 - 0.22 10.4 0.7 0.3 9.9 0.7 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 WD40 PF00400.32 CBY19508.1 - 3.8e-05 24.4 0.9 0.67 10.9 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Tubulin-binding PF00418.19 CBY19508.1 - 0.15 12.1 0.4 0.36 10.9 0.4 1.7 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat BTB_2 PF02214.22 CBY19511.1 - 8.8e-20 70.9 0.4 1.9e-19 69.8 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 CBY19511.1 - 1.2e-12 47.6 0.7 1.8e-12 47.1 0.7 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_3 PF16017.5 CBY19511.1 - 0.0036 17.4 0.0 0.011 15.8 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain DUF2828 PF11443.8 CBY19511.1 - 0.16 10.0 0.0 0.24 9.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pyridoxal_deC PF00282.19 CBY19512.1 - 1.5e-97 326.6 0.1 2e-97 326.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CBY19512.1 - 6.7e-06 25.3 0.1 9.9e-06 24.7 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBY19512.1 - 2.1e-05 23.9 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 CBY19512.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS OKR_DC_1 PF01276.20 CBY19512.1 - 0.067 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 CBY19512.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DnaJ PF00226.31 CBY19514.1 - 3.7e-18 65.4 3.2 6.7e-18 64.6 3.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF5523 PF17661.1 CBY19514.1 - 0.16 11.6 12.1 0.21 11.2 12.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Presenilin PF01080.17 CBY19514.1 - 0.43 9.3 4.1 0.5 9.1 4.1 1.1 1 0 0 1 1 1 0 Presenilin DUF1682 PF07946.14 CBY19514.1 - 0.55 9.4 13.7 0.82 8.8 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 CBY19514.1 - 1.4 8.7 10.5 1.8 8.3 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rgp1 PF08737.10 CBY19514.1 - 1.6 7.8 5.2 2 7.5 5.2 1.1 1 0 0 1 1 1 0 Rgp1 DUF4407 PF14362.6 CBY19514.1 - 2.9 7.1 8.3 3.6 6.8 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 CBY19514.1 - 5.1 5.3 9.1 6.1 5.0 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FKBP_N PF01346.18 CBY19514.1 - 7.6 7.6 15.6 5.9 7.9 0.2 2.3 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TFIIA PF03153.13 CBY19515.1 - 0.0069 16.4 11.7 0.011 15.8 11.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Mei4 PF13971.6 CBY19515.1 - 0.0091 15.5 0.4 0.016 14.7 0.4 1.3 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 Ald_Xan_dh_C PF01315.22 CBY19515.1 - 0.098 13.0 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain PDGF_N PF04692.13 CBY19515.1 - 7.9 7.3 7.5 1.2 10.0 2.3 2.3 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Peptidase_C28 PF05408.11 CBY19516.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase MitoNEET_N PF10660.9 CBY19518.1 - 0.095 12.7 0.1 0.095 12.7 0.1 1.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus L_HMGIC_fpl PF10242.9 CBY19520.1 - 0.0065 16.7 8.8 0.0065 16.7 8.8 1.5 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 CBY19520.1 - 1.3 8.5 12.8 0.33 10.4 0.6 2.3 1 1 0 2 2 2 0 Clc-like SUR7 PF06687.12 CBY19520.1 - 2.3 7.8 20.1 3.2 7.3 16.7 2.8 2 1 0 2 2 2 0 SUR7/PalI family G8 PF10162.9 CBY19521.1 - 7.3e-52 174.6 0.0 9.5e-27 93.5 0.0 2.8 2 0 0 2 2 2 2 G8 domain EGF_CA PF07645.15 CBY19521.1 - 8.7e-34 115.5 98.2 3.7e-06 27.0 10.8 7.1 6 0 0 6 6 6 6 Calcium-binding EGF domain TIG PF01833.24 CBY19521.1 - 8.1e-21 73.9 31.7 1.3e-10 41.1 0.1 7.5 9 0 0 9 9 9 3 IPT/TIG domain cEGF PF12662.7 CBY19521.1 - 1.9e-13 50.0 50.0 7.6e-05 22.5 2.3 6.7 6 0 0 6 6 6 5 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY19521.1 - 7.5e-13 48.4 94.8 1.7e-08 34.5 11.2 7.7 7 0 0 7 7 7 4 EGF domain Beta_helix PF13229.6 CBY19521.1 - 8.8e-09 35.4 30.4 5.8e-05 23.0 3.7 5.5 5 0 0 5 5 5 2 Right handed beta helix region FXa_inhibition PF14670.6 CBY19521.1 - 0.0028 17.9 5.3 0.0028 17.9 5.3 7.2 6 1 1 7 7 7 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY19521.1 - 0.0052 17.1 6.6 0.0052 17.1 6.6 7.8 7 0 0 7 7 7 5 EGF-like domain EGF_MSP1_1 PF12946.7 CBY19521.1 - 7.8 6.6 62.6 0.012 15.7 6.3 6.0 5 0 0 5 5 5 0 MSP1 EGF domain 1 LrgA PF03788.14 CBY19523.1 - 0.058 13.3 1.0 0.17 11.8 1.0 1.7 1 0 0 1 1 1 0 LrgA family DUF3487 PF11990.8 CBY19523.1 - 0.72 9.8 3.2 2.8 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) HAP1_N PF04849.13 CBY19524.1 - 0.00017 20.9 4.3 0.00017 20.9 4.3 5.2 1 1 4 5 5 5 1 HAP1 N-terminal conserved region MscS_porin PF12795.7 CBY19524.1 - 0.0067 16.0 10.7 0.0067 16.0 10.7 4.9 4 1 0 5 5 5 1 Mechanosensitive ion channel porin domain Trimer_CC PF08954.11 CBY19524.1 - 0.0089 15.6 0.4 0.0089 15.6 0.4 5.3 5 0 0 5 5 5 1 Trimerisation motif DivIC PF04977.15 CBY19524.1 - 0.021 14.6 0.9 0.021 14.6 0.9 9.5 6 3 5 11 11 11 0 Septum formation initiator SlyX PF04102.12 CBY19524.1 - 0.061 13.9 0.4 0.061 13.9 0.4 9.0 6 3 4 10 10 10 0 SlyX ATP-grasp_6 PF18419.1 CBY19524.1 - 0.067 12.8 0.4 3.4 7.4 0.1 3.1 2 0 0 2 2 2 0 ATP-grasp-like domain KASH_CCD PF14662.6 CBY19524.1 - 0.36 10.7 68.1 0.29 10.9 8.6 6.5 2 1 4 6 6 6 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 CBY19524.1 - 0.88 10.0 62.2 0.13 12.8 11.2 5.6 1 1 4 5 5 5 0 Fez1 Taxilin PF09728.9 CBY19524.1 - 8.3 5.5 58.3 26 3.8 2.8 4.8 1 1 2 3 3 3 0 Myosin-like coiled-coil protein CCDC106 PF15794.5 CBY19525.1 - 0.71 9.5 4.4 0.75 9.5 4.4 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ras PF00071.22 CBY19526.1 - 6.3e-40 136.4 0.0 8.1e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY19526.1 - 3.5e-17 62.7 0.0 5.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY19526.1 - 2.1e-06 27.3 0.0 3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY19526.1 - 0.0062 16.1 0.0 0.048 13.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TPP_enzyme_M PF00205.22 CBY19526.1 - 0.036 13.8 0.0 0.086 12.6 0.0 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain MMR_HSR1 PF01926.23 CBY19526.1 - 0.036 14.1 0.0 0.072 13.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 CBY19526.1 - 0.064 12.7 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 CBY19526.1 - 0.089 12.3 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region GSHPx PF00255.19 CBY19527.1 - 5.4e-20 71.0 0.0 6.9e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 CBY19528.1 - 9.5e-05 21.9 0.1 0.00011 21.8 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase UQ_con PF00179.26 CBY19529.1 - 0.0011 18.6 0.1 0.002 17.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme CytochromB561_N PF09786.9 CBY19529.1 - 0.079 12.0 2.4 0.1 11.6 2.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hrs_helical PF12210.8 CBY19529.1 - 0.18 12.4 4.2 18 6.0 0.0 2.4 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate RNase_T PF00929.24 CBY19531.1 - 6.9e-09 36.5 0.1 2.3e-08 34.8 0.1 1.8 1 1 0 1 1 1 1 Exonuclease zf-met PF12874.7 CBY19531.1 - 1.7e-05 25.0 1.0 3.4e-05 24.1 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY19531.1 - 0.0001 22.5 0.3 0.0002 21.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DNA_pol_A_exo1 PF01612.20 CBY19531.1 - 0.0082 15.9 0.2 0.027 14.2 0.0 2.0 2 1 0 2 2 2 1 3'-5' exonuclease zf-C2HE PF16278.5 CBY19531.1 - 0.026 15.0 0.9 0.25 11.8 0.2 2.3 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PseudoU_synth_2 PF00849.22 CBY19531.1 - 0.07 13.2 0.4 0.16 12.0 0.4 1.7 1 1 0 1 1 1 0 RNA pseudouridylate synthase zf-U1 PF06220.12 CBY19531.1 - 0.13 12.1 0.2 0.23 11.2 0.2 1.5 1 0 0 1 1 1 0 U1 zinc finger zf_C2H2_ZHX PF18387.1 CBY19531.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Inhibitor_I10 PF12559.8 CBY19532.1 - 0.1 12.9 0.8 9.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Serine endopeptidase inhibitors DUF1126 PF06565.12 CBY19533.1 - 4.6e-86 283.5 0.6 1.9e-28 98.4 0.0 3.8 3 1 0 3 3 3 3 DUF1126 PH-like domain RHH_7 PF16777.5 CBY19533.1 - 0.016 15.6 0.2 12 6.4 0.0 2.9 3 0 0 3 3 3 0 Transcriptional regulator, RHH-like, CopG Glyco_hydro_9 PF00759.19 CBY19536.1 - 4.4e-32 112.0 0.0 5.1e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Connexin PF00029.19 CBY19537.1 - 4.3e-86 288.5 9.4 5e-86 288.2 9.4 1.0 1 0 0 1 1 1 1 Connexin Glyco_hydro_9 PF00759.19 CBY19538.1 - 1.2e-73 249.0 8.6 1.7e-73 248.4 8.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sushi PF00084.20 CBY19538.1 - 0.00016 22.2 1.9 0.00041 20.9 1.9 1.8 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) CBM_2 PF00553.19 CBY19538.1 - 0.032 14.5 0.0 0.094 13.0 0.0 1.8 1 0 0 1 1 1 0 Cellulose binding domain RNase_T PF00929.24 CBY19539.1 - 2.6e-13 50.8 0.0 3.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF1364 PF07102.12 CBY19539.1 - 0.14 12.0 0.1 0.38 10.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1364) cNMP_binding PF00027.29 CBY19540.1 - 8.5e-12 45.0 0.1 2.2e-07 30.9 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain CLIP PF12032.8 CBY19540.1 - 0.66 10.3 2.4 6.3 7.2 0.5 2.6 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases Ras PF00071.22 CBY19541.1 - 2.8e-51 173.3 0.0 3.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY19541.1 - 2.2e-30 105.3 0.1 4.7e-30 104.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY19541.1 - 1.9e-10 40.4 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY19541.1 - 0.00014 21.9 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zip PF02535.22 CBY19542.1 - 1.2e-33 116.7 27.0 2.4e-26 92.8 16.5 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF21 PF01595.20 CBY19542.1 - 0.01 15.6 3.1 0.01 15.6 3.1 2.6 3 1 1 4 4 4 0 Cyclin M transmembrane N-terminal domain fn3 PF00041.21 CBY19543.1 - 1.4e-05 25.3 0.1 0.0073 16.6 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain FlaG PF03646.15 CBY19543.1 - 0.051 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 FlaG protein PhoPQ_related PF10142.9 CBY19545.1 - 5.9e-34 117.3 0.5 2.4e-33 115.3 0.5 1.8 1 1 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Ax_dynein_light PF10211.9 CBY19546.1 - 0.0026 17.8 0.1 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Axonemal dynein light chain Bromodomain PF00439.25 CBY19548.1 - 8.8e-81 266.1 15.9 5.4e-21 74.5 0.5 5.7 6 0 0 6 6 6 4 Bromodomain BAH PF01426.18 CBY19548.1 - 2.6e-18 66.0 0.3 6.2e-18 64.8 0.3 1.6 1 0 0 1 1 1 1 BAH domain HMG_box PF00505.19 CBY19548.1 - 2.7e-12 46.9 0.6 6.8e-12 45.6 0.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY19548.1 - 1e-11 45.3 0.3 3.2e-11 43.7 0.3 1.8 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 CBY19548.1 - 0.03 14.3 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 CHDNT (NUC034) domain WD40 PF00400.32 CBY19549.1 - 2.8e-39 132.4 15.9 1.2e-06 29.2 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 CBY19549.1 - 4.2e-16 58.6 0.9 1e-15 57.3 0.9 1.7 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 CBY19549.1 - 3.1e-11 43.4 0.6 0.034 14.4 0.1 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY19549.1 - 6.3e-09 35.6 0.1 7.5e-05 22.2 0.0 2.7 1 1 1 3 3 3 3 WD40-like domain F-box-like PF12937.7 CBY19549.1 - 1.2e-06 28.4 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.6 CBY19549.1 - 6.7e-06 26.1 0.2 0.34 11.0 0.0 4.2 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 CBY19549.1 - 1.2e-05 24.2 3.3 0.96 8.0 0.0 4.5 2 2 2 4 4 4 2 Nucleoporin Nup120/160 120_Rick_ant PF12574.8 CBY19549.1 - 0.00029 20.1 0.1 0.14 11.3 0.0 2.2 1 1 1 2 2 2 2 120 KDa Rickettsia surface antigen F-box PF00646.33 CBY19549.1 - 0.0016 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.11 CBY19549.1 - 0.024 13.4 1.5 1.6 7.4 0.0 3.7 1 1 2 4 4 4 0 Nup133 N terminal like DUF5046 PF16465.5 CBY19549.1 - 0.088 12.2 0.3 1.4 8.3 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 CBY19549.1 - 0.14 11.8 0.1 1.2 8.7 0.1 2.1 1 1 1 2 2 2 0 PQQ-like domain Invas_SpaK PF03519.14 CBY19549.1 - 0.16 12.0 0.4 2 8.6 0.1 2.7 2 1 1 3 3 3 0 Invasion protein B family AAA_5 PF07728.14 CBY19550.1 - 6e-90 298.4 0.0 4.5e-29 101.2 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY19550.1 - 3.4e-08 34.1 8.1 0.066 13.6 0.0 5.9 4 2 2 6 6 5 2 AAA ATPase domain AAA_3 PF07726.11 CBY19550.1 - 2.5e-07 30.6 0.0 0.075 12.9 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CBY19550.1 - 6.8e-07 28.9 0.1 0.74 9.2 0.0 4.5 3 1 1 4 4 4 1 Magnesium chelatase, subunit ChlI CbbQ_C PF08406.10 CBY19550.1 - 1.3e-06 28.6 0.2 0.0034 17.6 0.2 2.9 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA_2 PF07724.14 CBY19550.1 - 5.7e-06 26.5 0.0 0.092 12.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBY19550.1 - 1.9e-05 24.9 1.6 0.19 12.0 0.0 4.5 3 2 0 3 3 3 1 AAA domain AAA PF00004.29 CBY19550.1 - 2.3e-05 24.8 0.0 0.7 10.3 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBY19550.1 - 0.00015 21.8 0.0 2.6 8.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CBY19550.1 - 0.00016 21.9 0.1 3.3 7.8 0.0 4.0 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.17 CBY19550.1 - 0.00092 19.0 0.0 4 7.1 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CBY19550.1 - 0.002 18.1 0.0 0.81 9.6 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase MCM PF00493.23 CBY19550.1 - 0.0023 17.1 0.0 0.016 14.3 0.0 2.4 3 0 0 3 3 3 1 MCM P-loop domain Roc PF08477.13 CBY19550.1 - 0.0079 16.4 0.0 0.79 9.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CBY19550.1 - 0.0096 16.4 0.0 1.4 9.4 0.0 2.8 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.12 CBY19550.1 - 0.0097 15.7 0.4 16 5.2 0.0 3.6 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CBY19550.1 - 0.011 15.4 0.0 2.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.6 CBY19550.1 - 0.015 15.8 0.5 6.8 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_8 PF12780.7 CBY19550.1 - 0.053 12.8 0.5 6.2 6.1 0.0 3.5 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 NACHT PF05729.12 CBY19550.1 - 0.064 13.2 0.7 23 4.8 0.0 4.1 4 1 0 4 4 4 0 NACHT domain Zeta_toxin PF06414.12 CBY19550.1 - 0.074 12.3 0.0 0.68 9.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 CBY19550.1 - 0.16 12.0 0.1 19 5.2 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBY19550.1 - 0.17 11.4 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region PQQ_2 PF13360.6 CBY19551.1 - 1.2e-08 34.8 0.0 0.0017 18.0 0.0 3.4 2 2 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 CBY19551.1 - 0.013 16.0 0.0 1.4 9.5 0.0 3.3 2 0 0 2 2 2 0 PQQ-like domain MMS1_N PF10433.9 CBY19551.1 - 0.04 12.6 1.3 6.8 5.2 0.2 2.9 2 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PP-binding PF00550.25 CBY19551.1 - 0.04 14.3 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site AMP-binding PF00501.28 CBY19551.1 - 0.041 12.5 0.0 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme Transglut_N PF00868.20 CBY19552.1 - 3.2e-27 95.2 0.0 7.5e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 CBY19552.1 - 8.2e-16 58.4 0.1 1.6e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SRF-TF PF00319.18 CBY19552.1 - 0.038 13.5 0.1 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) MICSWaP PF17018.5 CBY19552.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Spore wall protein Collagen PF01391.18 CBY19553.1 - 1.1e-51 172.4 309.8 1.7e-06 27.7 8.9 21.7 15 4 5 22 22 22 18 Collagen triple helix repeat (20 copies) Oxidored-like PF09791.9 CBY19553.1 - 0.001 18.7 5.0 4.4 7.0 0.0 3.7 3 0 0 3 3 3 3 Oxidoreductase-like protein, N-terminal DUF1819 PF08849.11 CBY19553.1 - 0.0013 18.6 0.4 1.3 8.8 0.1 2.1 2 0 0 2 2 2 2 Putative inner membrane protein (DUF1819) CX9C PF16860.5 CBY19553.1 - 0.012 15.6 1.6 44 4.2 0.0 3.4 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3854 PF12965.7 CBY19553.1 - 0.07 13.1 1.3 4 7.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3854) RCC1_2 PF13540.6 CBY19553.1 - 0.096 12.5 0.0 31 4.5 0.0 2.9 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat PDDEXK_4 PF14281.6 CBY19553.1 - 0.3 11.2 0.2 31 4.7 0.0 2.9 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily DUF5302 PF17227.2 CBY19553.1 - 2.9 9.0 7.4 1.5e+02 3.5 0.2 4.4 3 0 0 3 3 3 0 Family of unknown function (DUF5302) DUF2521 PF10730.9 CBY19554.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) GST_C_2 PF13410.6 CBY19555.1 - 3.2e-06 27.1 0.1 5.4e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBY19555.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY19555.1 - 0.03 14.6 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EF-hand_7 PF13499.6 CBY19556.1 - 1.2e-10 41.6 4.7 2.4e-09 37.5 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY19556.1 - 2.3e-10 39.3 0.4 2.2e-06 26.8 0.3 3.8 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 CBY19556.1 - 2.9e-09 36.1 4.4 0.00023 20.8 0.0 3.6 4 1 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY19556.1 - 4.2e-09 35.5 1.0 0.0026 17.2 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 CBY19556.1 - 4.6e-06 26.5 2.4 1.8e-05 24.6 0.4 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBY19556.1 - 0.016 16.1 1.4 0.97 10.3 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain Lipoprotein_Ltp PF07553.11 CBY19556.1 - 0.02 15.2 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein Dockerin_1 PF00404.18 CBY19556.1 - 0.042 14.0 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_8 PF13833.6 CBY19556.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.4 4 1 1 5 5 5 0 EF-hand domain pair HSP70 PF00012.20 CBY19557.1 - 2.6e-64 217.5 28.8 2.7e-64 217.4 17.8 2.6 1 1 2 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBY19557.1 - 0.0034 16.2 5.1 0.017 14.0 5.1 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Hfq PF17209.3 CBY19557.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Hfq protein DUF2518 PF10726.9 CBY19557.1 - 0.099 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of function (DUF2518) DHHC PF01529.20 CBY19560.1 - 1e-36 126.0 16.2 1e-36 126.0 16.2 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3810 PF12725.7 CBY19560.1 - 8.9 5.6 9.7 3.8 6.8 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) zf-RING_UBOX PF13445.6 CBY19561.1 - 1.1e-06 28.6 0.2 6.5e-06 26.1 0.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY19561.1 - 5.3e-06 26.3 5.6 1.5e-05 24.9 5.6 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY19561.1 - 1.1e-05 25.7 6.0 5.7e-05 23.4 6.0 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY19561.1 - 6.4e-05 22.7 5.7 0.00083 19.2 5.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY19561.1 - 0.0013 18.4 3.9 0.003 17.2 3.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBY19561.1 - 0.0024 17.7 1.2 0.0024 17.7 1.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY19561.1 - 0.0051 16.6 3.0 0.19 11.5 3.0 2.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CBY19561.1 - 0.045 13.6 3.5 0.91 9.4 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 CBY19561.1 - 0.45 10.7 6.2 5.1 7.3 6.2 2.5 1 1 0 1 1 1 0 FYVE zinc finger Rhodanese_C PF12368.8 CBY19561.1 - 0.49 10.8 5.9 0.24 11.8 0.7 2.7 3 0 0 3 3 3 0 Rhodanase C-terminal Rad50_zn_hook PF04423.14 CBY19561.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 CBY19561.1 - 0.83 10.0 7.2 1.7 9.0 3.4 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain DUF4337 PF14235.6 CBY19561.1 - 1 9.4 4.4 0.36 10.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) MRP-L28 PF09812.9 CBY19561.1 - 1.5 9.0 10.1 0.13 12.4 3.5 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L28 TUDOR PF00567.24 CBY19562.1 - 3.5e-23 81.9 0.5 3.6e-09 36.7 0.0 5.0 5 0 0 5 5 5 4 Tudor domain Ank_5 PF13857.6 CBY19563.1 - 2.3e-12 46.9 2.4 3.5e-09 36.7 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY19563.1 - 3.7e-11 43.4 0.1 9.4e-11 42.2 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY19563.1 - 9.9e-10 38.4 0.1 0.0013 19.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CBY19563.1 - 5.4e-09 36.4 0.2 5.1e-08 33.3 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY19563.1 - 6.3e-07 29.2 0.3 0.0005 20.3 0.1 3.1 2 1 0 2 2 2 2 Ankyrin repeat EGF PF00008.27 CBY19564.1 - 1.1e-72 239.8 245.9 5.2e-09 36.2 6.3 19.2 18 2 1 19 19 19 14 EGF-like domain hEGF PF12661.7 CBY19564.1 - 2.4e-41 139.0 206.3 6.4e-07 29.8 6.5 19.0 19 0 0 19 19 19 14 Human growth factor-like EGF EGF_2 PF07974.13 CBY19564.1 - 2.3e-30 104.6 290.5 2.6e-05 24.5 8.7 19.6 19 1 0 19 19 19 15 EGF-like domain EGF_CA PF07645.15 CBY19564.1 - 8.4e-21 73.9 280.3 2.1e-08 34.3 10.3 19.2 9 4 11 20 20 20 10 Calcium-binding EGF domain DSL PF01414.19 CBY19564.1 - 9.7e-20 70.6 5.6 9.7e-20 70.6 5.6 14.7 11 4 6 17 17 17 3 Delta serrate ligand cEGF PF12662.7 CBY19564.1 - 0.00038 20.3 141.3 0.0073 16.2 2.8 17.2 16 0 0 16 16 16 10 Complement Clr-like EGF-like TMEM144 PF07857.12 CBY19565.1 - 2.1e-31 109.2 1.3 2.3e-31 109.0 1.3 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters ALMS_motif PF15309.6 CBY19566.1 - 3.4e-34 118.2 16.7 3.4e-34 118.2 16.7 3.9 4 1 0 4 4 4 1 ALMS motif PH_12 PF16457.5 CBY19567.1 - 3.7e-16 59.9 3.3 5.5e-16 59.3 0.4 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 CBY19567.1 - 2.4e-14 53.9 0.3 7.9e-14 52.1 0.1 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family Ank_2 PF12796.7 CBY19569.1 - 1.3e-23 83.4 0.0 2.4e-12 47.3 0.0 2.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY19569.1 - 6.1e-16 58.6 0.0 2.3e-07 31.2 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SH3_9 PF14604.6 CBY19569.1 - 1.4e-15 56.8 0.8 3e-15 55.8 0.3 1.8 2 0 0 2 2 2 1 Variant SH3 domain Ank_5 PF13857.6 CBY19569.1 - 9.3e-14 51.3 0.0 6e-07 29.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SH3_1 PF00018.28 CBY19569.1 - 5e-13 48.4 0.2 9.3e-13 47.6 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY19569.1 - 2e-11 43.4 0.4 6.7e-11 41.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain Ank_3 PF13606.6 CBY19569.1 - 1.9e-08 33.9 0.0 0.045 14.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CBY19569.1 - 7.5e-08 32.5 0.0 0.0048 17.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat DnaJ PF00226.31 CBY19570.1 - 1.8e-22 79.2 3.1 1.8e-22 79.2 3.1 2.0 3 0 0 3 3 3 1 DnaJ domain UPF0242 PF06785.11 CBY19570.1 - 0.15 12.2 0.2 0.15 12.2 0.2 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Frizzled PF01534.17 CBY19571.1 - 5e-18 65.2 2.2 3.6e-17 62.4 2.0 1.9 2 0 0 2 2 2 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CBY19571.1 - 8.6e-11 42.4 1.4 1.8e-10 41.4 1.4 1.6 1 0 0 1 1 1 1 Fz domain DUF1221 PF06760.11 CBY19572.1 - 0.012 15.1 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) RPEL PF02755.15 CBY19572.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 RPEL repeat Thyroglobulin_1 PF00086.18 CBY19573.1 - 1.1e-12 47.4 0.1 2.8e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Baculo_p33 PF05214.12 CBY19575.1 - 0.094 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P33 O-FucT PF10250.9 CBY19576.1 - 0.14 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase EF-hand_1 PF00036.32 CBY19577.1 - 2e-14 52.0 1.7 1.8e-06 27.1 0.5 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY19577.1 - 1.2e-12 46.7 1.0 1.1e-05 25.0 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY19577.1 - 1e-11 43.7 2.9 1.6e-05 24.2 0.7 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY19577.1 - 2.9e-09 37.2 0.2 3.7e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY19577.1 - 1.4e-08 34.5 0.9 0.00051 19.8 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair Caleosin PF05042.13 CBY19577.1 - 0.00038 20.4 0.4 0.35 10.8 0.1 2.0 1 1 1 2 2 2 2 Caleosin related protein EF-hand_10 PF14788.6 CBY19577.1 - 0.0027 17.5 0.8 0.01 15.7 0.4 1.9 1 1 1 2 2 2 1 EF hand DUF294_C PF10335.9 CBY19577.1 - 0.059 13.1 0.1 0.1 12.4 0.1 1.4 1 1 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain SPARC_Ca_bdg PF10591.9 CBY19577.1 - 0.098 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Arg_decarbox_C PF17944.1 CBY19577.1 - 0.2 12.2 0.4 16 6.2 0.1 2.2 1 1 1 2 2 2 0 Arginine decarboxylase C-terminal helical extension TMC PF07810.13 CBY19578.1 - 7.2e-32 110.3 0.4 9e-32 110.0 0.4 1.1 1 0 0 1 1 1 1 TMC domain zf-C2H2 PF00096.26 CBY19579.1 - 1.2e-06 28.6 7.3 0.0012 19.2 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY19579.1 - 0.016 16.0 0.7 0.016 16.0 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 CBY19579.1 - 0.033 14.8 0.3 0.033 14.8 0.3 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain SET PF00856.28 CBY19580.1 - 2.6e-09 37.7 1.1 3e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 SET domain DUF4570 PF15134.6 CBY19580.1 - 0.017 15.2 2.8 0.039 14.0 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) BTB PF00651.31 CBY19581.1 - 7.2e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Methyltr_RsmB-F PF01189.17 CBY19582.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F TUDOR PF00567.24 CBY19583.1 - 1e-11 44.9 0.0 3.2e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 Tudor domain KH_1 PF00013.29 CBY19583.1 - 1.7e-09 37.4 2.7 4.4e-09 36.0 0.4 2.7 2 0 0 2 2 2 1 KH domain Ras PF00071.22 CBY19584.1 - 1.2e-26 93.2 0.0 1.4e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY19584.1 - 4.6e-16 59.1 0.1 6.7e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY19584.1 - 3.9e-11 42.7 0.0 4.3e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY19584.1 - 0.00087 18.9 0.0 0.00093 18.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY19584.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ion_trans PF00520.31 CBY19585.1 - 1.7e-33 115.8 10.8 2.5e-33 115.4 10.8 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CBY19585.1 - 1.7e-13 50.7 0.0 6e-13 49.0 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 CBY19585.1 - 7.7e-13 48.2 2.0 7.7e-13 48.2 2.0 1.9 2 0 0 2 2 2 1 Ion channel ABC_membrane PF00664.23 CBY19586.1 - 2.5e-100 335.6 28.6 2e-51 175.3 12.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY19586.1 - 6e-70 234.1 3.1 1.9e-34 119.1 0.2 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBY19586.1 - 5.3e-16 58.7 2.3 7.4e-06 25.6 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY19586.1 - 1.3e-09 38.7 0.5 0.0013 19.2 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CBY19586.1 - 2.7e-08 33.9 0.2 0.006 16.5 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 CBY19586.1 - 1.3e-07 31.6 0.0 0.0023 17.7 0.0 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 CBY19586.1 - 2.6e-07 31.0 0.6 0.0094 16.2 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CBY19586.1 - 2.7e-07 30.2 1.1 0.0092 15.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 CBY19586.1 - 4.4e-06 26.3 0.0 0.096 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 CBY19586.1 - 7.5e-06 25.8 0.7 0.043 13.5 0.1 3.2 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CBY19586.1 - 2.3e-05 24.4 0.3 0.24 11.4 0.0 3.3 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CBY19586.1 - 2.8e-05 23.4 0.0 0.064 12.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) G-alpha PF00503.20 CBY19586.1 - 5.1e-05 22.6 0.3 0.027 13.6 0.0 3.5 3 1 0 3 3 3 1 G-protein alpha subunit AAA_24 PF13479.6 CBY19586.1 - 0.00021 21.1 0.0 0.026 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 CBY19586.1 - 0.00028 21.1 2.9 0.14 12.4 0.3 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 CBY19586.1 - 0.00034 20.6 0.1 0.56 10.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain NTPase_1 PF03266.15 CBY19586.1 - 0.0007 19.5 2.1 3.1 7.7 0.0 4.0 4 0 0 4 4 4 1 NTPase TsaE PF02367.17 CBY19586.1 - 0.0019 18.2 0.1 1.5 8.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CBY19586.1 - 0.002 18.5 3.1 3.9 7.9 0.0 4.2 5 0 0 5 5 3 1 RNA helicase MMR_HSR1 PF01926.23 CBY19586.1 - 0.0023 18.0 0.5 2.2 8.4 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase Sigma54_activat PF00158.26 CBY19586.1 - 0.0026 17.5 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF87 PF01935.17 CBY19586.1 - 0.0061 16.7 4.9 2.7 8.0 0.0 4.0 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_21 PF13304.6 CBY19586.1 - 0.0091 15.8 0.2 0.069 12.9 0.0 2.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 CBY19586.1 - 0.0095 15.7 1.9 0.087 12.6 0.1 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Zeta_toxin PF06414.12 CBY19586.1 - 0.011 15.1 0.2 0.54 9.5 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Roc PF08477.13 CBY19586.1 - 0.011 16.0 0.1 10 6.3 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 CBY19586.1 - 0.012 14.5 0.2 1 8.1 0.0 3.5 4 1 0 4 4 4 0 Predicted ATPase of the ABC class KAP_NTPase PF07693.14 CBY19586.1 - 0.016 14.5 0.6 1.1 8.4 0.1 3.1 3 1 0 3 3 3 0 KAP family P-loop domain AAA_25 PF13481.6 CBY19586.1 - 0.017 14.7 0.0 8.4 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 CBY19586.1 - 0.023 14.6 0.0 0.74 9.7 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 CBY19586.1 - 0.025 13.8 0.5 5.8 6.0 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain ATP-synt_ab PF00006.25 CBY19586.1 - 0.026 14.2 0.0 2 8.0 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 CBY19586.1 - 0.039 13.2 0.1 5.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 CBY19586.1 - 0.042 13.2 0.1 10 5.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 CBY19586.1 - 0.054 14.0 0.0 0.63 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CBY19586.1 - 0.089 12.5 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 CBY19586.1 - 0.11 12.7 0.0 8.8 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CBY19586.1 - 0.35 10.9 2.4 16 5.5 0.1 3.3 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 CBY19586.1 - 2.3 8.7 11.4 2 8.9 0.0 3.6 5 0 0 5 5 3 0 AAA domain Ion_trans PF00520.31 CBY19588.1 - 1.4e-15 57.2 15.2 1.9e-15 56.8 15.2 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY19588.1 - 6e-07 29.3 1.2 6e-07 29.3 1.2 2.1 2 0 0 2 2 2 1 Ion channel Bac_export_2 PF01312.19 CBY19588.1 - 0.068 12.4 1.5 0.14 11.4 1.5 1.4 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Form_Nir_trans PF01226.17 CBY19588.1 - 0.082 12.2 4.6 0.14 11.5 4.6 1.3 1 0 0 1 1 1 0 Formate/nitrite transporter LrgB PF04172.16 CBY19588.1 - 0.13 11.8 3.5 0.18 11.3 0.5 2.0 2 0 0 2 2 2 0 LrgB-like family NS3_envE PF02723.14 CBY19588.1 - 0.23 11.6 4.3 1.5 9.0 0.1 2.7 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Pre-SET PF05033.16 CBY19589.1 - 2.1e-07 31.6 8.3 2.2e-07 31.5 6.6 1.9 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 CBY19589.1 - 6.6e-05 23.4 0.1 0.00018 21.9 0.1 1.8 1 0 0 1 1 1 1 SET domain DUF2370 PF10176.9 CBY19590.1 - 0.17 11.5 1.1 0.32 10.6 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) cNMP_binding PF00027.29 CBY19591.1 - 4.5e-18 65.1 0.0 8.1e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CLZ PF16526.5 CBY19591.1 - 1.4e-06 28.5 3.9 3.9e-06 27.1 3.9 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ion_trans PF00520.31 CBY19591.1 - 1.2e-05 24.6 17.9 0.00099 18.4 18.1 2.2 1 1 0 1 1 1 1 Ion transport protein PcfK PF14058.6 CBY19592.1 - 0.19 12.0 0.6 9.3 6.5 0.1 2.4 2 0 0 2 2 2 0 PcfK-like protein LLC1 PF14945.6 CBY19593.1 - 1.2e-06 29.1 0.3 2.7e-05 24.7 0.2 2.2 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Ldl_recept_a PF00057.18 CBY19593.1 - 2.5e-05 24.4 3.5 2.5e-05 24.4 3.5 2.9 3 1 0 3 3 3 1 Low-density lipoprotein receptor domain class A PAW PF04721.17 CBY19594.1 - 6.6e-19 68.5 0.0 1.3e-18 67.5 0.0 1.3 1 1 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Sushi PF00084.20 CBY19594.1 - 0.047 14.3 3.0 0.5 11.0 0.8 3.2 2 1 1 3 3 3 0 Sushi repeat (SCR repeat) Vanabin-2 PF11437.8 CBY19594.1 - 1.9 8.7 6.9 11 6.2 0.2 2.6 2 0 0 2 2 2 0 Vanadium-binding protein 2 Sushi PF00084.20 CBY19595.1 - 1.6 9.3 9.4 0.5 11.0 3.6 2.6 1 1 1 2 2 2 0 Sushi repeat (SCR repeat) RXLR PF16810.5 CBY19596.1 - 0.48 10.8 3.2 0.69 10.4 1.0 2.1 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Coprogen_oxidas PF01218.18 CBY19597.1 - 3.5e-122 406.8 0.1 3.9e-122 406.6 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Peptidase_M48_N PF16491.5 CBY19598.1 - 6.3e-53 179.4 12.1 6.3e-53 179.4 12.1 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CBY19598.1 - 1.9e-43 148.5 0.0 2.8e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Pro_isomerase PF00160.21 CBY19599.1 - 6e-43 146.8 0.3 1.1e-42 145.9 0.3 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CBY19599.1 - 4.8e-09 35.6 10.9 0.00075 19.4 0.2 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY19599.1 - 1e-05 25.1 4.9 0.11 12.4 0.6 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY19599.1 - 5.2e-05 23.8 3.8 0.0013 19.4 2.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY19599.1 - 8.1e-05 23.1 2.8 8.1e-05 23.1 2.8 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY19599.1 - 8.8e-05 22.4 6.7 0.057 13.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY19599.1 - 0.00012 22.2 0.1 0.0003 21.0 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY19599.1 - 0.00017 22.1 2.8 0.0037 18.0 0.7 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat Nop14 PF04147.12 CBY19599.1 - 0.0052 15.1 3.9 0.0052 15.1 3.9 2.0 1 1 0 2 2 2 1 Nop14-like family TPR_11 PF13414.6 CBY19599.1 - 0.0061 16.2 7.0 0.39 10.4 0.1 3.5 2 1 1 3 3 3 1 TPR repeat TPR_20 PF14561.6 CBY19599.1 - 0.0066 16.8 1.3 0.019 15.3 1.3 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY19599.1 - 0.0095 16.2 1.8 23 5.4 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY19599.1 - 0.066 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat ChAPs PF09295.10 CBY19599.1 - 0.12 11.4 0.4 0.16 10.9 0.4 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CBY19599.1 - 0.33 11.7 6.8 4.1 8.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY19599.1 - 1.8 8.8 5.0 0.36 11.1 1.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CBY19599.1 - 5.4 7.2 11.7 0.11 12.5 1.1 2.6 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Phos_pyr_kin PF08543.12 CBY19600.1 - 7.7e-16 58.2 0.0 1.8e-15 57.0 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CBY19600.1 - 4.1e-05 23.0 0.0 0.008 15.5 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Carb_kinase PF01256.17 CBY19600.1 - 0.072 12.6 0.0 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 Carbohydrate kinase PIF1 PF05970.14 CBY19601.1 - 1.4e-59 202.1 4.9 4.1e-43 148.0 0.2 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CBY19601.1 - 2.3e-16 60.1 0.0 4.9e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY19601.1 - 3.8e-10 40.3 0.0 3.6e-09 37.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 CBY19601.1 - 5.1e-06 24.7 0.2 0.00053 18.1 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.6 CBY19601.1 - 3.6e-05 24.1 0.0 0.00018 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBY19601.1 - 0.00057 19.9 0.2 0.0031 17.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY19601.1 - 0.00078 19.9 0.0 0.0021 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 CBY19601.1 - 0.0014 18.2 0.1 0.0054 16.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 CBY19601.1 - 0.0017 18.8 0.3 0.007 16.8 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CBY19601.1 - 0.0023 17.7 0.2 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CBY19601.1 - 0.0058 15.7 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 CBY19601.1 - 0.0076 16.0 0.2 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 CBY19601.1 - 0.012 15.6 0.0 0.056 13.5 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 CBY19601.1 - 0.013 15.3 2.0 4.7 6.9 0.0 3.4 3 1 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 CBY19601.1 - 0.024 14.3 0.3 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 CBY19601.1 - 0.038 13.4 0.1 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 CBY19601.1 - 0.052 13.3 0.3 7.6 6.3 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 CBY19601.1 - 0.053 12.8 0.1 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Hydant_A_N PF05378.13 CBY19601.1 - 0.069 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Sigma54_activ_2 PF14532.6 CBY19601.1 - 0.083 13.0 0.3 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 CBY19601.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY19601.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CBY19601.1 - 0.26 11.8 1.6 0.57 10.7 0.2 2.3 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 CBY19601.1 - 0.51 9.8 3.2 0.33 10.4 0.4 2.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain LIN37 PF15306.6 CBY19602.1 - 2.2e-14 53.9 3.9 4e-08 33.6 0.1 2.1 1 1 1 2 2 2 2 LIN37 Interfer-bind PF09294.10 CBY19602.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III RabGAP-TBC PF00566.18 CBY19603.1 - 2.3e-30 105.8 1.8 1.7e-29 103.0 1.8 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CBY19604.1 - 1.9e-50 171.7 0.0 2.6e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19604.1 - 2.3e-20 73.0 0.0 3.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CBY19604.1 - 0.00027 20.6 0.3 0.00061 19.4 0.2 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY19604.1 - 0.0039 17.2 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY19604.1 - 0.0044 16.4 0.2 0.51 9.6 0.2 2.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY19604.1 - 0.0064 15.9 0.2 0.01 15.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY19604.1 - 0.009 15.6 0.3 0.15 11.6 0.0 2.2 1 1 1 2 2 2 1 RIO1 family ABC1 PF03109.16 CBY19604.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Ca_hom_mod PF14798.6 CBY19605.1 - 0.0097 15.0 0.3 0.0097 15.0 0.3 1.5 1 1 1 2 2 2 1 Calcium homeostasis modulator Shisa PF13908.6 CBY19605.1 - 0.012 15.9 2.4 0.017 15.4 2.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.6 CBY19605.1 - 0.078 11.4 1.3 0.099 11.0 1.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 CBY19605.1 - 0.088 13.8 0.1 0.17 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3899 PF13038.6 CBY19605.1 - 0.78 10.3 2.1 1.1 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) TRAP-gamma PF07074.12 CBY19605.1 - 2.9 7.4 6.9 2.7 7.5 0.2 2.1 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Spc7 PF08317.11 CBY19606.1 - 0.0037 16.2 35.4 0.13 11.1 23.8 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CBY19606.1 - 0.19 11.7 41.5 1.6 8.7 13.8 4.1 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 CBY19606.1 - 0.24 11.2 39.6 2.9 7.6 12.2 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Taxilin PF09728.9 CBY19606.1 - 0.52 9.4 35.0 0.75 8.9 35.0 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Baculo_PEP_C PF04513.12 CBY19606.1 - 1.7 8.7 10.3 2.4 8.2 3.3 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 CBY19606.1 - 2.7 7.3 40.1 3.5 6.9 31.5 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 CBY19606.1 - 5.1 7.5 31.8 7.5 7.0 9.7 2.3 1 1 1 2 2 2 0 Fez1 CUB PF00431.20 CBY19608.1 - 2.9e-12 46.9 1.2 3.3e-08 33.8 0.0 2.6 2 1 1 3 3 3 2 CUB domain CUB_2 PF02408.20 CBY19608.1 - 0.0048 16.7 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 CUB-like domain LamB PF02264.15 CBY19608.1 - 0.021 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 LamB porin Alpha_L_fucos PF01120.17 CBY19609.1 - 2.4e-101 339.7 6.6 4.8e-101 338.7 6.6 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase AKAP7_NLS PF10469.9 CBY19609.1 - 1.9e-45 155.3 3.4 2.7e-45 154.8 3.4 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 CBY19609.1 - 6.8e-10 38.6 0.2 1.5e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 KH domain GHL6 PF14871.6 CBY19609.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 adh_short PF00106.25 CBY19610.1 - 9.3e-27 93.8 0.1 1e-20 74.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY19610.1 - 3.1e-25 89.1 0.0 3.6e-19 69.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY19610.1 - 1.9e-06 27.9 0.0 2.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY19610.1 - 0.00012 21.6 0.0 0.00081 18.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBY19610.1 - 0.049 12.6 0.0 0.062 12.3 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CBY19610.1 - 0.095 12.1 0.1 2 7.7 0.0 2.2 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1907 PF08925.11 CBY19611.1 - 6.9e-106 353.8 0.0 7.9e-106 353.6 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) IBN_N PF03810.19 CBY19612.1 - 5.3e-12 45.5 0.0 5.7e-09 35.8 0.0 3.2 2 0 0 2 2 2 2 Importin-beta N-terminal domain Cse1 PF08506.10 CBY19612.1 - 0.00023 20.1 2.3 0.00046 19.1 0.6 2.2 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 CBY19612.1 - 0.0036 17.4 0.2 0.091 12.8 0.0 3.2 2 0 0 2 2 2 1 Exportin 1-like protein Sulf_coat_C PF12193.8 CBY19612.1 - 0.052 13.6 0.4 0.84 9.7 0.5 2.4 2 0 0 2 2 2 0 Sulfolobus virus coat protein C terminal Ku_PK_bind PF08785.11 CBY19612.1 - 0.076 13.2 0.9 0.81 9.9 0.2 2.9 3 0 0 3 3 3 0 Ku C terminal domain like adh_short PF00106.25 CBY19613.1 - 2.3e-24 85.9 1.2 4.2e-24 85.1 1.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY19613.1 - 7.4e-18 65.0 0.2 1.1e-17 64.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CBY19613.1 - 0.00051 20.0 0.1 0.00065 19.6 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CBY19613.1 - 0.0053 15.9 0.0 0.0091 15.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 CBY19613.1 - 0.14 12.1 0.5 0.2 11.5 0.2 1.8 2 1 0 2 2 2 0 KR domain adh_short PF00106.25 CBY19614.1 - 2e-22 79.6 0.2 2.7e-22 79.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY19614.1 - 2.2e-16 60.1 0.3 3e-16 59.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CBY19614.1 - 0.00035 20.5 0.1 0.00049 20.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CBY19614.1 - 0.0062 16.5 0.0 0.015 15.3 0.0 1.6 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 CBY19614.1 - 0.0098 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 CBY19614.1 - 0.051 13.0 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2358 PF10184.9 CBY19616.1 - 6.1e-06 26.5 0.0 8.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) zf-MYND PF01753.18 CBY19617.1 - 7.2e-06 26.0 17.2 7.2e-06 26.0 17.2 2.6 2 0 0 2 2 2 1 MYND finger DUF2805 PF10985.8 CBY19617.1 - 0.04 14.3 0.6 0.15 12.4 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Pap_E4 PF02711.14 CBY19617.1 - 1 10.3 7.0 19 6.3 3.0 3.4 2 0 0 2 2 2 0 E4 protein DUF2894 PF11445.8 CBY19617.1 - 3.6 8.0 10.3 1.8 9.0 2.2 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2894) BRAP2 PF07576.12 CBY19618.1 - 2.1e-26 92.0 0.0 6.7e-26 90.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CBY19618.1 - 1.2e-19 70.4 5.3 1.2e-19 70.4 5.3 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CBY19618.1 - 2.4e-09 37.4 7.1 2.4e-09 37.4 7.1 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY19618.1 - 1.9e-07 30.8 6.5 5.1e-07 29.4 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY19618.1 - 1.3e-06 28.0 2.6 3.6e-06 26.6 2.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CBY19618.1 - 3.1e-06 27.4 4.7 3.1e-06 27.4 4.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBY19618.1 - 4.1e-06 26.7 2.3 2.1e-05 24.4 2.3 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY19618.1 - 4.7e-05 23.2 7.1 4.7e-05 23.2 7.1 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY19618.1 - 0.00016 21.6 5.5 0.00016 21.6 5.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY19618.1 - 0.00076 19.3 4.3 0.00076 19.3 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1672 PF07901.11 CBY19618.1 - 0.0023 17.3 10.5 0.0038 16.6 10.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1672) zf-RING_4 PF14570.6 CBY19618.1 - 0.0071 16.1 3.6 0.025 14.4 3.6 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CBY19618.1 - 0.0075 16.3 1.3 0.0075 16.3 1.3 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBY19618.1 - 0.0097 15.8 5.5 0.0097 15.8 5.5 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-UBP_var PF17807.1 CBY19618.1 - 0.017 14.9 0.4 0.059 13.1 0.4 1.9 1 0 0 1 1 1 0 Variant UBP zinc finger zf-RING_6 PF14835.6 CBY19618.1 - 0.031 14.1 1.4 0.066 13.1 1.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HGTP_anticodon PF03129.20 CBY19618.1 - 0.11 12.7 3.1 0.32 11.2 3.1 1.8 1 0 0 1 1 1 0 Anticodon binding domain zf-C3H2C3 PF17122.5 CBY19618.1 - 0.12 12.4 5.1 0.34 11.0 5.1 1.9 1 0 0 1 1 1 0 Zinc-finger Tim29 PF10171.9 CBY19618.1 - 0.3 10.6 3.7 3 7.3 0.1 2.4 2 0 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 DUF2935 PF11155.8 CBY19618.1 - 0.51 10.7 6.2 1.7 9.0 6.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) RINGv PF12906.7 CBY19618.1 - 0.76 9.9 8.8 3.2 8.0 8.8 2.2 1 1 0 1 1 1 0 RING-variant domain Tropomyosin_1 PF12718.7 CBY19618.1 - 3.1 7.9 29.6 2 8.6 7.3 3.0 1 1 1 2 2 2 0 Tropomyosin like Zn_ribbon_17 PF17120.5 CBY19618.1 - 3.9 7.2 13.3 0.16 11.6 4.7 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF4407 PF14362.6 CBY19618.1 - 7.2 5.9 12.7 11 5.3 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4_4 PF15227.6 CBY19618.1 - 7.3 6.8 8.8 6 7.1 2.8 2.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Homeodomain PF00046.29 CBY19619.1 - 6.8e-11 41.9 14.1 6.5e-08 32.3 4.1 3.8 3 1 0 3 3 3 2 Homeodomain Homez PF11569.8 CBY19619.1 - 0.00099 18.5 0.3 0.019 14.4 0.0 2.8 3 0 0 3 3 3 1 Homeodomain leucine-zipper encoding, Homez DUF1098 PF06497.11 CBY19619.1 - 0.035 14.6 0.1 0.13 12.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) Homeobox_KN PF05920.11 CBY19619.1 - 0.037 13.9 2.1 0.044 13.7 0.4 2.0 2 0 0 2 2 2 0 Homeobox KN domain ArsA_HSP20 PF17886.1 CBY19619.1 - 0.15 11.7 0.1 11 5.6 0.1 2.8 1 1 0 1 1 1 0 HSP20-like domain found in ArsA F-112 PF09645.10 CBY19619.1 - 3.7 7.7 8.6 3.6 7.7 0.7 2.7 2 0 0 2 2 2 0 F-112 protein WD40 PF00400.32 CBY19620.1 - 2e-06 28.4 5.8 0.39 11.7 0.1 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY19620.1 - 7.9e-05 22.9 0.9 0.67 10.3 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY19620.1 - 0.0001 21.1 0.1 0.00015 20.6 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CBY19620.1 - 0.00029 19.7 0.2 0.31 9.7 0.2 2.3 1 1 1 2 2 2 2 Nup133 N terminal like Vps16_N PF04841.13 CBY19620.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Vps16, N-terminal region Tetraspanin PF00335.20 CBY19621.1 - 3.9e-08 33.3 1.2 1.6e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 Tetraspanin family BTB_2 PF02214.22 CBY19622.1 - 1.6e-20 73.2 0.1 2.6e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CBY19622.1 - 0.0057 16.9 0.2 0.0096 16.1 0.2 1.4 1 1 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CBY19622.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain Vinculin PF01044.19 CBY19623.1 - 3.5e-114 383.1 27.2 5.4e-88 296.4 21.1 2.2 1 1 1 2 2 2 2 Vinculin family PHA_synth_III_E PF09712.10 CBY19623.1 - 0.1 11.7 3.2 0.15 11.1 0.2 2.6 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Glycos_transf_2 PF00535.26 CBY19624.1 - 2.3e-23 82.9 0.0 4.7e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY19624.1 - 0.0002 21.6 0.1 0.00042 20.6 0.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CBY19624.1 - 0.00064 19.3 0.2 0.0021 17.7 0.2 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DOR PF14839.6 CBY19624.1 - 3.4 7.6 15.1 0.11 12.4 6.2 2.3 2 0 0 2 2 2 0 DOR family RIB43A PF05914.12 CBY19625.1 - 2.9e-93 312.6 52.2 4.2e-93 312.1 52.2 1.1 1 0 0 1 1 1 1 RIB43A Rax2 PF12768.7 CBY19627.1 - 0.072 12.5 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DM PF00751.18 CBY19628.1 - 2.1e-22 78.7 10.8 3.6e-22 78.0 10.8 1.4 1 0 0 1 1 1 1 DM DNA binding domain DMA PF03474.14 CBY19628.1 - 2.8e-15 55.6 0.1 5e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 DMRTA motif Frag1 PF10277.9 CBY19629.1 - 7.8e-24 84.4 11.4 1.1e-23 83.9 11.4 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 CBY19629.1 - 0.00057 19.5 1.3 0.0012 18.5 1.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF998) Claudin_2 PF13903.6 CBY19629.1 - 0.02 14.6 1.1 0.045 13.5 1.1 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction CALCOCO1 PF07888.11 CBY19630.1 - 0.017 14.0 14.9 0.04 12.8 12.2 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Rootletin PF15035.6 CBY19630.1 - 0.11 12.6 10.6 0.086 12.9 9.2 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Golgin_A5 PF09787.9 CBY19630.1 - 0.24 10.9 17.2 0.28 10.6 17.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 SNARE PF05739.19 CBY19630.1 - 0.47 10.5 4.5 1.6 8.8 0.4 3.1 3 0 0 3 3 3 0 SNARE domain GrpE PF01025.19 CBY19630.1 - 1.3 8.6 11.1 1.3 8.7 10.3 1.3 1 1 0 1 1 1 0 GrpE CENP-F_leu_zip PF10473.9 CBY19630.1 - 1.5 8.9 16.9 0.51 10.3 12.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 CBY19630.1 - 2.5 7.9 13.2 3.4 7.4 9.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 CBY19630.1 - 4.1 7.6 14.7 0.29 11.3 8.9 1.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 CBY19630.1 - 4.4 8.0 15.7 9.7 6.9 2.9 2.8 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 CBY19630.1 - 6.7 7.2 16.6 0.99 9.9 7.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 CBY19630.1 - 7.5 7.3 14.0 20 5.9 11.6 2.5 1 1 1 2 2 2 0 Initiation control protein YabA EMP70 PF02990.16 CBY19632.1 - 6e-208 691.7 17.7 8.9e-208 691.1 17.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 CBY19632.1 - 0.0019 17.2 17.0 0.0019 17.2 17.0 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 CBY19632.1 - 2.8 8.0 0.0 2.8 8.0 0.0 4.8 3 2 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Cys_rich_FGFR PF00839.17 CBY19633.1 - 1.1e-128 419.4 97.9 2.9e-12 46.6 1.2 16.4 16 0 0 16 16 16 16 Cysteine rich repeat Tup_N PF08581.10 CBY19633.1 - 0.35 11.2 3.7 0.55 10.6 1.2 2.6 3 0 0 3 3 3 0 Tup N-terminal Tmemb_161AB PF10268.9 CBY19634.1 - 9.2e-68 229.0 9.4 6.3e-67 226.2 7.8 2.1 1 1 0 1 1 1 1 Predicted transmembrane protein 161AB RapH_N PF18801.1 CBY19634.1 - 0.053 13.6 2.7 0.089 12.9 0.9 2.1 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF5426 PF17473.2 CBY19634.1 - 0.099 12.9 0.4 0.099 12.9 0.4 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5426) Herpes_UL6 PF01763.16 CBY19634.1 - 0.13 10.8 0.6 0.19 10.2 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1891 PF09004.10 CBY19634.1 - 3.7 7.2 5.8 1.9 8.2 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1891) UPF0242 PF06785.11 CBY19635.1 - 0.0053 16.9 8.8 0.011 15.8 8.8 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Adaptin_binding PF10199.9 CBY19635.1 - 1.5 9.4 9.9 1.4 9.6 3.7 2.7 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 ATP-synt_E PF05680.12 CBY19635.1 - 1.6 9.1 13.0 1.7 9.0 11.2 2.0 2 0 0 2 2 2 0 ATP synthase E chain V_ATPase_I PF01496.19 CBY19635.1 - 1.9 6.3 8.3 2.3 6.0 8.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1840 PF08895.11 CBY19635.1 - 5.3 7.4 11.1 12 6.3 4.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Cpn60_TCP1 PF00118.24 CBY19636.1 - 3.9e-155 517.2 16.5 4.4e-155 517.0 16.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family YchF-GTPase_C PF06071.13 CBY19637.1 - 1.7e-35 121.1 1.2 1.7e-35 121.1 1.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CBY19637.1 - 1.2e-21 76.9 0.0 3.9e-21 75.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY19637.1 - 8.5e-07 28.6 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CBY19637.1 - 0.014 15.5 0.0 7.6 6.6 0.0 3.0 2 1 1 3 3 3 0 Dynamin family TGS PF02824.21 CBY19637.1 - 0.086 12.9 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 TGS domain AAA_14 PF13173.6 CBY19637.1 - 0.09 12.8 0.0 5.2 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain GLTP PF08718.11 CBY19638.1 - 9.2e-31 107.1 0.0 1.1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Pro_isomerase PF00160.21 CBY19639.1 - 2e-48 164.7 0.0 3.6e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CBY19639.1 - 4.7e-09 36.7 0.8 2.1 9.3 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY19639.1 - 0.0091 15.0 0.6 2.5 7.0 0.0 3.5 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CBY19639.1 - 0.038 12.7 0.1 0.077 11.7 0.1 1.4 1 0 0 1 1 1 0 Nup133 N terminal like CRM1_C PF08767.11 CBY19639.1 - 0.078 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal MMS1_N PF10433.9 CBY19639.1 - 0.082 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term CBFD_NFYB_HMF PF00808.23 CBY19640.1 - 2.1e-29 101.6 0.9 4.4e-29 100.6 0.9 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY19640.1 - 9e-06 26.1 0.4 1.7e-05 25.2 0.3 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 CBY19640.1 - 0.0005 20.1 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 CBY19640.1 - 0.0022 18.1 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 CBY19640.1 - 0.063 13.8 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-X PF09415.10 CBY19640.1 - 0.1 12.9 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF4416 PF14385.6 CBY19642.1 - 0.0081 16.1 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4416) Gal-3-0_sulfotr PF06990.11 CBY19644.1 - 4.1e-36 124.7 0.0 4.5e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY19644.1 - 1.7e-05 24.9 0.0 2.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY19644.1 - 0.061 12.8 0.1 0.089 12.3 0.1 1.3 1 1 0 1 1 1 0 Sulfotransferase domain Gal-3-0_sulfotr PF06990.11 CBY19645.1 - 1.3e-30 106.6 1.9 2.1e-30 105.9 1.9 1.4 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase DUF5362 PF17319.2 CBY19645.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5362) HECT PF00632.25 CBY19646.1 - 3.9e-87 292.6 0.0 8.7e-87 291.5 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 CBY19646.1 - 7.9e-05 22.1 0.0 0.00041 19.9 0.0 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif PUF PF00806.19 CBY19647.1 - 7.7e-07 28.5 0.0 3.9e-05 23.1 0.0 3.4 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat DUF1400 PF07176.11 CBY19647.1 - 0.033 14.5 0.0 6.1 7.2 0.0 3.1 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) Cyclin_C PF02984.19 CBY19647.1 - 0.096 12.8 0.0 0.67 10.1 0.0 2.4 3 0 0 3 3 3 0 Cyclin, C-terminal domain DnaJ PF00226.31 CBY19650.1 - 2.3e-19 69.3 0.1 7.5e-19 67.6 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 CBY19650.1 - 5.8e-15 55.2 1.4 2.9e-07 30.6 0.6 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain MAP7 PF05672.11 CBY19650.1 - 0.0051 16.5 27.3 0.0051 16.5 27.3 2.6 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family Myb_DNA-bind_6 PF13921.6 CBY19650.1 - 0.085 13.1 14.6 0.21 11.8 0.7 4.1 4 0 0 4 4 4 0 Myb-like DNA-binding domain ELM2 PF01448.24 CBY19650.1 - 2.5 8.9 0.0 2.5 8.9 0.0 3.1 2 1 0 2 2 2 0 ELM2 domain Presenilin PF01080.17 CBY19650.1 - 3.4 6.3 9.2 1.1 7.9 2.6 2.2 2 0 0 2 2 2 0 Presenilin V-ATPase_G PF03179.15 CBY19651.1 - 1.7e-30 105.7 16.0 1.9e-30 105.5 16.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit NINJA_B PF16136.5 CBY19651.1 - 0.05 14.0 5.1 0.064 13.6 5.1 1.1 1 0 0 1 1 1 0 Putative nuclear localisation signal vATP-synt_E PF01991.18 CBY19651.1 - 0.087 12.2 11.1 0.1 12.0 11.1 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF1690 PF07956.11 CBY19651.1 - 0.28 11.6 8.2 0.45 10.9 8.2 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) GA PF01468.17 CBY19651.1 - 0.68 10.3 9.0 0.33 11.2 0.7 2.9 3 0 0 3 3 3 0 GA module OmpH PF03938.14 CBY19651.1 - 0.7 10.2 17.6 0.9 9.9 17.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CBY19651.1 - 2 7.7 9.2 2.4 7.4 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 CBY19651.1 - 3.3 6.7 8.0 4 6.4 8.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V-ATPase_G_2 PF16999.5 CBY19651.1 - 3.3 8.2 17.2 5.3 7.5 17.2 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit UPF0242 PF06785.11 CBY19651.1 - 5.2 7.1 10.5 7 6.7 10.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATP-synt_B PF00430.18 CBY19651.1 - 9.5 6.3 20.1 2.6 8.1 16.2 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF3775 PF12616.8 CBY19652.1 - 0.00039 20.4 0.1 0.001 19.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3775) HEAT PF02985.22 CBY19653.1 - 0.00038 20.5 1.0 2.3 8.7 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CBY19653.1 - 0.039 14.3 0.1 0.16 12.3 0.0 2.2 3 0 0 3 3 3 0 HEAT repeats Pkinase PF00069.25 CBY19654.1 - 3.8e-37 128.1 0.1 1.4e-36 126.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19654.1 - 5.6e-18 65.1 0.0 5.6e-13 48.8 0.0 2.8 2 0 0 2 2 2 2 Protein tyrosine kinase TRM13 PF05206.14 CBY19655.1 - 1.6e-50 172.1 5.4 5.3e-50 170.4 1.8 2.8 2 1 0 2 2 2 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 CBY19655.1 - 1.2e-10 41.0 4.3 1.2e-10 41.0 4.3 2.4 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Methyltransf_31 PF13847.6 CBY19655.1 - 0.0003 20.6 0.1 0.00069 19.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CBY19655.1 - 0.0008 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 CBY19655.1 - 0.0016 18.5 7.4 0.0051 16.8 7.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain DUF4416 PF14385.6 CBY19655.1 - 0.0032 17.4 0.5 0.0088 16.0 0.2 1.8 1 1 0 2 2 2 1 Domain of unknown function (DUF4416) Sgf11 PF08209.11 CBY19655.1 - 0.014 15.0 0.7 0.032 13.8 0.7 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) FtsJ PF01728.19 CBY19655.1 - 0.035 14.2 0.0 0.45 10.6 0.0 2.3 1 1 1 2 2 2 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 CBY19655.1 - 0.069 13.9 0.0 0.18 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain SET PF00856.28 CBY19656.1 - 9.8e-19 68.4 1.3 2.9e-18 66.8 1.3 1.8 1 1 0 1 1 1 1 SET domain preSET_CXC PF18264.1 CBY19656.1 - 6e-11 42.6 16.6 6e-11 42.6 16.6 4.2 4 1 0 4 4 4 1 CXC domain TCR PF03638.15 CBY19656.1 - 8.6 6.8 45.3 0.064 13.6 12.9 3.9 4 0 0 4 4 4 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain EzrA PF06160.12 CBY19657.1 - 0.00043 18.6 22.2 0.00061 18.1 22.2 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Atg14 PF10186.9 CBY19657.1 - 0.0013 17.9 22.4 0.0064 15.6 8.2 2.3 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 CBY19657.1 - 0.076 13.1 10.0 0.72 9.9 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF730 PF05325.11 CBY19657.1 - 0.57 10.2 9.1 0.64 10.1 1.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF730) RPW8 PF05659.11 CBY19657.1 - 0.7 9.6 11.3 1.3 8.7 3.5 2.5 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SKA1 PF07160.12 CBY19657.1 - 2.7 7.8 25.1 0.21 11.4 15.2 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4201 PF13870.6 CBY19657.1 - 2.7 7.7 30.7 0.12 12.1 16.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Laminin_II PF06009.12 CBY19657.1 - 5.7 7.0 19.4 12 6.0 4.3 2.5 1 1 1 2 2 2 0 Laminin Domain II bZIP_1 PF00170.21 CBY19657.1 - 8.7 6.5 24.3 0.16 12.1 1.9 4.1 3 1 0 4 4 4 0 bZIP transcription factor UNC45-central PF11701.8 CBY19658.1 - 3.4e-25 88.8 12.1 2.3e-24 86.1 0.3 3.6 3 1 0 3 3 3 2 Myosin-binding striated muscle assembly central TPR_1 PF00515.28 CBY19658.1 - 6.2e-08 32.1 0.2 0.006 16.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY19658.1 - 1e-06 28.3 0.1 0.0038 17.2 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Arm PF00514.23 CBY19658.1 - 6.2e-06 26.1 7.7 4 7.6 0.4 6.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CBY19658.1 - 0.0001 22.6 3.2 4.3 7.8 0.0 5.6 3 3 4 7 7 7 1 HEAT repeats HEAT PF02985.22 CBY19658.1 - 0.00079 19.5 8.0 6.1 7.4 0.3 6.3 7 0 0 7 7 7 1 HEAT repeat TPR_7 PF13176.6 CBY19658.1 - 0.0028 17.6 0.1 0.04 14.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat SIL1 PF16782.5 CBY19658.1 - 0.0042 16.4 0.6 0.79 8.9 0.0 3.2 3 0 0 3 3 3 1 Nucleotide exchange factor SIL1 TPR_12 PF13424.6 CBY19658.1 - 0.0045 17.2 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY19658.1 - 0.0057 17.1 0.3 2.2 8.9 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY19658.1 - 0.032 14.4 0.7 19 5.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 CBY19658.1 - 0.037 14.6 0.2 29 5.3 0.2 3.8 3 0 0 3 3 2 0 HEAT-like repeat Cnd1 PF12717.7 CBY19658.1 - 0.25 11.4 12.7 2.3 8.3 0.2 4.9 6 0 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Fringe PF02434.16 CBY19659.1 - 2.5e-42 145.1 0.0 8.7e-40 136.7 0.0 2.4 2 1 0 2 2 2 2 Fringe-like Glycos_transf_2 PF00535.26 CBY19659.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CBY19659.1 - 0.019 14.5 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CBY19659.1 - 0.15 11.9 0.0 2 8.2 0.0 2.1 1 1 1 2 2 2 0 Glycosyltransferase like family 2 BRO1 PF03097.18 CBY19660.1 - 4.8e-40 137.6 3.7 6e-40 137.2 3.7 1.0 1 0 0 1 1 1 1 BRO1-like domain Ion_trans PF00520.31 CBY19661.1 - 4e-51 173.6 38.2 6e-33 114.1 17.8 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 CBY19661.1 - 3 6.4 32.7 0.025 13.3 4.7 4.5 4 0 0 4 4 4 0 Polycystin cation channel DUF3342 PF11822.8 CBY19662.1 - 2.2e-24 85.5 0.2 4.3e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) CHORD PF04968.12 CBY19662.1 - 7.4e-05 23.4 5.2 0.00021 21.9 5.2 1.8 1 0 0 1 1 1 1 CHORD BTB PF00651.31 CBY19662.1 - 0.011 16.0 0.1 0.047 13.9 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Sulfotransfer_2 PF03567.14 CBY19663.1 - 5.1e-14 52.8 1.6 5.6e-14 52.7 1.6 1.0 1 0 0 1 1 1 1 Sulfotransferase family DUF624 PF04854.14 CBY19663.1 - 0.076 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Pkinase PF00069.25 CBY19664.1 - 8.3e-40 136.8 0.0 2.1e-20 73.2 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19664.1 - 8.7e-08 31.8 3.3 6.1e-06 25.7 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY19664.1 - 0.028 13.2 0.5 0.077 11.8 0.4 1.8 1 1 0 1 1 1 0 Fungal protein kinase SR-25 PF10500.9 CBY19664.1 - 3.4 7.2 14.8 1 8.9 1.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GATA PF00320.27 CBY19666.1 - 8.9e-27 92.4 17.8 1.4e-13 50.2 7.5 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CBY19666.1 - 0.056 13.0 8.6 0.38 10.3 0.6 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 CBY19666.1 - 0.35 10.9 6.1 3.3 7.8 5.8 2.4 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.21 CBY19666.1 - 3.2 7.9 8.8 25 5.1 8.8 2.2 1 1 0 1 1 1 0 FYVE zinc finger Connexin PF00029.19 CBY19667.1 - 1.4e-39 136.2 2.0 1.8e-38 132.7 2.0 2.0 1 1 0 1 1 1 1 Connexin SecD-TM1 PF13721.6 CBY19667.1 - 0.0091 16.4 0.4 0.036 14.5 0.1 2.1 2 0 0 2 2 2 1 SecD export protein N-terminal TM region DUF2681 PF10883.8 CBY19667.1 - 0.045 14.2 5.1 0.063 13.7 3.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) zf-PHD-like PF15446.6 CBY19668.1 - 0.1 12.2 0.3 0.14 11.7 0.3 1.3 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-C4H2 PF10146.9 CBY19670.1 - 0.003 17.9 2.7 0.17 12.1 1.8 2.1 2 0 0 2 2 2 2 Zinc finger-containing protein QVR PF17064.5 CBY19670.1 - 0.044 14.0 2.9 0.044 14.0 2.9 3.2 2 1 2 4 4 4 0 Sleepless protein SWI-SNF_Ssr4 PF08549.10 CBY19670.1 - 0.85 8.2 6.7 0.88 8.1 6.7 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FtsH_ext PF06480.15 CBY19670.1 - 8.7 6.8 11.8 4.5 7.7 7.4 2.5 2 1 0 2 2 2 0 FtsH Extracellular Pkinase_Tyr PF07714.17 CBY19672.1 - 1.8e-10 40.5 0.0 2.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY19672.1 - 2.4e-06 27.1 0.0 3.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.8 CBY19672.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Neur_chan_LBD PF02931.23 CBY19673.1 - 3.4e-37 128.0 0.3 4.2e-37 127.7 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY19673.1 - 1.1e-24 87.9 6.3 1.5e-24 87.4 6.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region F5_F8_type_C PF00754.25 CBY19678.1 - 4.2e-09 36.6 0.0 8.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain LCCL PF03815.19 CBY19678.1 - 1.9e-07 31.1 0.0 4.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 LCCL domain RVT_1 PF00078.27 CBY19679.1 - 1.8e-32 112.7 0.0 4.7e-32 111.3 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nsp1 PF11501.8 CBY19680.1 - 0.17 12.0 0.0 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Non structural protein Nsp1 Iron_traffic PF04362.14 CBY19682.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking EF-hand_1 PF00036.32 CBY19685.1 - 5.2e-06 25.6 0.2 2.2e-05 23.7 0.0 2.2 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 CBY19685.1 - 2.5e-05 23.8 0.1 7.7e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CBY19685.1 - 0.0028 18.1 0.4 0.0042 17.5 0.3 1.4 1 1 0 1 1 1 1 EF-hand domain pair Nuc_sug_transp PF04142.15 CBY19687.1 - 3.3e-22 79.1 16.0 8.6e-22 77.7 16.0 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBY19687.1 - 0.0059 16.8 5.3 0.0059 16.8 5.3 2.2 1 1 0 2 2 2 1 EamA-like transporter family Phage_holin_3_3 PF16083.5 CBY19687.1 - 0.06 13.5 0.3 0.15 12.2 0.3 1.7 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III 7tm_1 PF00001.21 CBY19688.1 - 3.2e-16 59.5 13.9 8.5e-15 54.8 13.9 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 CBY19688.1 - 0.033 13.3 9.6 0.1 11.7 9.6 1.9 1 1 0 1 1 1 0 Taste receptor protein (TAS2R) Yip1 PF04893.17 CBY19688.1 - 6.2 6.5 11.4 0.13 11.9 2.3 2.3 2 1 0 2 2 2 0 Yip1 domain DUF3671 PF12420.8 CBY19688.1 - 9.1 6.4 11.7 10 6.3 4.2 2.7 1 1 1 2 2 2 0 Protein of unknown function Nuc_sug_transp PF04142.15 CBY19689.1 - 2.2e-25 89.5 25.5 5e-25 88.3 25.5 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBY19689.1 - 0.00046 20.4 26.6 0.0027 17.9 3.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 CBY19689.1 - 0.037 13.3 24.2 0.026 13.8 8.9 2.2 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 CBY19691.1 - 2.2e-25 89.5 25.5 5e-25 88.3 25.5 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBY19691.1 - 0.00046 20.4 26.6 0.0027 17.9 3.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 CBY19691.1 - 0.037 13.3 24.2 0.026 13.8 8.9 2.2 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport Gal-3-0_sulfotr PF06990.11 CBY19692.1 - 1.8e-16 60.1 0.4 2.3e-16 59.7 0.4 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Nucleos_tra2_C PF07662.13 CBY19693.1 - 7.6e-62 208.8 1.7 7.6e-62 208.8 1.7 2.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CBY19693.1 - 2.8e-15 56.7 9.7 1.3e-14 54.5 9.7 2.3 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CBY19693.1 - 1e-05 25.8 6.0 1e-05 25.8 6.0 3.7 5 0 0 5 5 5 1 Nucleoside recognition PIRT PF15099.6 CBY19693.1 - 5.1 6.7 5.9 3.2 7.3 2.7 2.3 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family TLD PF07534.16 CBY19694.1 - 1.9e-31 109.2 0.3 3.6e-31 108.2 0.3 1.5 1 0 0 1 1 1 1 TLD LysM PF01476.20 CBY19694.1 - 5.3e-05 23.2 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 LysM domain GRAM PF02893.20 CBY19694.1 - 0.026 14.4 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 GRAM domain RRM_1 PF00076.22 CBY19695.1 - 3.1e-15 55.7 0.0 5.5e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DBB PF14545.6 CBY19695.1 - 0.0039 17.1 0.1 0.0074 16.2 0.1 1.5 1 1 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, IFP_35_N PF07334.13 CBY19695.1 - 0.099 12.7 1.6 0.17 12.0 1.6 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GBP_C PF02841.14 CBY19695.1 - 0.17 11.3 6.2 0.22 10.9 6.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4140 PF13600.6 CBY19695.1 - 1.4 9.4 4.8 2.7 8.5 4.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3050 PF11251.8 CBY19696.1 - 1e-90 303.5 0.0 1.3e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Haem_oxygenas_2 PF14518.6 CBY19696.1 - 3.8e-05 23.5 0.0 9e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Iron-containing redox enzyme Stomoxyn PF11585.8 CBY19697.1 - 0.048 13.7 1.2 0.048 13.7 1.2 1.8 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn Cation_efflux PF01545.21 CBY19699.1 - 3.1e-52 177.2 17.6 1.4e-32 113.1 3.8 3.1 3 0 0 3 3 3 3 Cation efflux family PRD1_DD PF11087.8 CBY19699.1 - 0.089 12.5 0.3 0.25 11.0 0.1 1.9 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery DC_STAMP PF07782.13 CBY19699.1 - 0.7 9.7 5.2 0.38 10.5 0.4 2.6 3 0 0 3 3 3 0 DC-STAMP-like protein DUF2065 PF09838.9 CBY19699.1 - 0.88 9.6 13.4 8.8 6.4 2.9 3.6 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Cation_efflux PF01545.21 CBY19700.1 - 1.8e-08 34.4 2.2 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Cation efflux family DUF866 PF05907.13 CBY19701.1 - 0.044 13.7 0.4 0.051 13.5 0.4 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) RRM_1 PF00076.22 CBY19703.1 - 7.5e-18 64.1 0.2 1.3e-17 63.4 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY19703.1 - 0.00042 20.4 0.1 0.0016 18.5 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CBY19703.1 - 0.038 13.6 0.1 0.075 12.6 0.0 1.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DCX PF03607.17 CBY19704.1 - 2.4e-09 37.1 0.0 7.4e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Doublecortin CDP-OH_P_transf PF01066.21 CBY19705.1 - 1.6e-15 57.6 0.3 1.6e-15 57.6 0.3 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Colicin_V PF02674.16 CBY19705.1 - 0.0064 16.5 1.5 0.019 15.0 1.5 1.8 1 0 0 1 1 1 1 Colicin V production protein Phospholip_A2_1 PF00068.19 CBY19706.1 - 1e-10 42.0 1.9 1.4e-10 41.7 1.9 1.1 1 0 0 1 1 1 1 Phospholipase A2 DUF3895 PF13034.6 CBY19706.1 - 0.041 13.9 0.1 0.074 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3895) Phospholip_A2_1 PF00068.19 CBY19707.1 - 1.6e-17 64.0 10.5 1.6e-17 64.0 10.5 2.1 1 1 1 2 2 2 2 Phospholipase A2 ETRAMP PF09716.10 CBY19708.1 - 0.032 14.3 0.1 0.047 13.8 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF5345 PF17280.2 CBY19708.1 - 0.054 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) CTP_transf_like PF01467.26 CBY19710.1 - 1.4e-36 125.8 0.1 7.4e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase-like Ctr PF04145.15 CBY19712.1 - 3e-18 66.8 13.3 5e-11 43.4 7.3 2.0 1 1 1 2 2 2 2 Ctr copper transporter family ThiW PF09512.10 CBY19712.1 - 0.0093 16.1 0.3 0.014 15.5 0.3 1.2 1 0 0 1 1 1 1 Thiamine-precursor transporter protein (ThiW) Rer1 PF03248.13 CBY19713.1 - 0.0049 16.6 2.8 0.042 13.6 0.1 2.2 1 1 1 2 2 2 1 Rer1 family Lysis_col PF02402.16 CBY19713.1 - 0.011 15.4 3.1 0.19 11.4 0.1 2.4 2 0 0 2 2 2 0 Lysis protein Calcyon PF06387.11 CBY19713.1 - 0.04 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) E1-E2_ATPase PF00122.20 CBY19713.1 - 0.43 10.1 4.8 0.35 10.4 0.2 2.2 1 1 0 2 2 2 0 E1-E2 ATPase EF-hand_1 PF00036.32 CBY19714.1 - 5.6e-05 22.4 1.0 0.055 13.0 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY19714.1 - 0.00075 19.2 5.0 0.12 12.4 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBY19714.1 - 0.0012 18.6 0.8 2.3 8.1 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 CBY19714.1 - 0.0031 17.9 1.6 0.023 15.2 1.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY19714.1 - 0.036 14.4 0.4 5.8 7.3 0.2 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Phage_int_SAM_3 PF14659.6 CBY19714.1 - 1.1 9.6 5.6 0.45 10.8 0.6 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Neur_chan_LBD PF02931.23 CBY19715.1 - 1.5e-41 142.2 0.1 1.5e-41 142.2 0.1 1.9 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY19715.1 - 7.2e-32 111.3 1.8 1.6e-31 110.2 1.8 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region COX2-transmemb PF09125.10 CBY19715.1 - 0.12 12.2 1.1 0.29 11.0 1.1 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Importin_rep_6 PF18829.1 CBY19715.1 - 0.13 12.4 1.7 0.28 11.3 1.7 1.6 1 0 0 1 1 1 0 Importin repeat 6 DivIC PF04977.15 CBY19715.1 - 0.15 11.8 1.8 0.35 10.7 1.8 1.6 1 0 0 1 1 1 0 Septum formation initiator MgtE PF01769.16 CBY19715.1 - 0.58 10.6 6.0 0.46 10.9 1.1 2.6 3 0 0 3 3 3 0 Divalent cation transporter Orf78 PF06024.12 CBY19715.1 - 1.8 8.9 4.5 0.72 10.2 0.4 2.4 1 1 1 2 2 2 0 Orf78 (ac78) Peptidase_S49_N PF08496.10 CBY19715.1 - 4.7 7.3 5.8 3.8 7.6 0.5 2.2 1 1 1 2 2 2 0 Peptidase family S49 N-terminal CBM_14 PF01607.24 CBY19716.1 - 7.4e-21 74.1 24.2 4.9e-13 49.0 6.1 2.8 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain FSA_C PF10479.9 CBY19716.1 - 2.6 6.1 14.0 4.5 5.3 14.0 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus OmdA PF13376.6 CBY19717.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DEC-1_N PF04625.13 CBY19717.1 - 0.61 9.0 6.0 0.14 11.2 2.5 1.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Spore_GerQ PF09671.10 CBY19721.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) Shisa PF13908.6 CBY19722.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PDZ_6 PF17820.1 CBY19723.1 - 5e-06 26.3 0.1 9.6e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY19723.1 - 2.4e-05 24.6 0.0 6.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Tom22 PF04281.13 CBY19723.1 - 1.1 9.1 7.2 2.1 8.1 7.2 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SAPS PF04499.15 CBY19723.1 - 2.1 7.0 10.0 2.1 7.0 10.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Urocanase_C PF17392.2 CBY19724.1 - 3.9e-83 277.7 0.7 6e-83 277.1 0.7 1.2 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 CBY19724.1 - 1.3e-76 256.9 0.0 2.2e-76 256.2 0.0 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 CBY19724.1 - 3.9e-52 175.3 0.3 1.2e-51 173.7 0.3 1.9 1 0 0 1 1 1 1 Urocanase N-terminal domain Pkinase PF00069.25 CBY19726.1 - 1.7e-53 181.7 0.0 2.2e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19726.1 - 1.1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY19726.1 - 0.00011 21.7 0.0 0.00026 20.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CBY19726.1 - 0.04 13.8 0.0 0.15 11.9 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CBY19727.1 - 1.2e-68 231.3 0.1 1.5e-68 231.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19727.1 - 5.7e-34 117.6 0.0 7.9e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY19727.1 - 1.7e-06 27.5 0.0 2.9e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY19727.1 - 0.025 14.0 0.1 0.037 13.4 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tetraspanin PF00335.20 CBY19729.1 - 5e-13 49.3 2.4 6.4e-13 49.0 2.4 1.1 1 0 0 1 1 1 1 Tetraspanin family FixQ PF05545.11 CBY19729.1 - 5.5 7.0 6.3 2.2 8.3 0.2 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Profilin PF00235.19 CBY19730.1 - 1.2e-14 54.7 0.0 1.4e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 Profilin Peptidase_M2 PF01401.18 CBY19731.1 - 1.1e-180 602.1 5.5 1.3e-180 601.8 5.5 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M3 PF01432.20 CBY19731.1 - 0.0039 16.5 3.2 0.034 13.4 3.2 2.2 1 1 0 1 1 1 1 Peptidase family M3 UQ_con PF00179.26 CBY19732.1 - 4.1e-37 127.0 0.0 4.9e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PI-PLC-X PF00388.19 CBY19734.1 - 1.5e-58 196.5 0.1 3.3e-58 195.4 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY19734.1 - 1.1e-38 132.1 0.4 3.2e-38 130.6 0.4 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH2 PF00017.24 CBY19734.1 - 6.6e-27 93.4 0.3 2.8e-14 53.0 0.0 3.5 4 0 0 4 4 4 2 SH2 domain SH3_1 PF00018.28 CBY19734.1 - 8.4e-10 38.1 0.5 2.7e-09 36.5 0.5 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY19734.1 - 1.4e-09 37.6 0.0 4.9e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CBY19734.1 - 5.9e-06 25.9 0.0 2e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain PH_14 PF17787.1 CBY19734.1 - 0.0006 19.7 0.2 0.11 12.3 0.0 3.6 3 1 0 3 3 3 1 PH domain Peptidase_M14 PF00246.24 CBY19734.1 - 0.0013 18.6 0.4 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 Zinc carboxypeptidase Pyr_redox_2 PF07992.14 CBY19735.1 - 3.3e-55 187.4 0.3 4.6e-55 186.9 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBY19735.1 - 2.2e-21 76.2 0.0 5e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBY19735.1 - 1.7e-17 63.7 1.2 2.2e-13 50.5 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Glutaredoxin PF00462.24 CBY19735.1 - 4.7e-16 58.8 0.0 9.6e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Pyr_redox_3 PF13738.6 CBY19735.1 - 3.1e-15 56.2 0.0 1.3e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY19735.1 - 5.7e-07 29.0 1.3 4e-06 26.2 0.9 2.3 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 CBY19735.1 - 1.6e-05 24.4 0.0 0.0028 17.0 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 CBY19735.1 - 0.0002 20.8 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CBY19735.1 - 0.00067 19.0 0.2 0.0013 18.1 0.2 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 CBY19735.1 - 0.00084 18.5 0.7 0.0018 17.5 0.7 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBY19735.1 - 0.0024 16.7 2.3 0.0027 16.5 0.3 2.0 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.6 CBY19735.1 - 0.0087 15.2 0.0 0.028 13.5 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thioredoxin_2 PF13098.6 CBY19735.1 - 0.035 14.6 0.3 0.12 12.8 0.3 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 CBY19735.1 - 0.045 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) NAD_binding_8 PF13450.6 CBY19735.1 - 0.051 13.8 0.4 0.051 13.8 0.4 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GST_N_3 PF13417.6 CBY19735.1 - 0.11 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain tRNA-synt_2b PF00587.25 CBY19737.1 - 2.5e-36 125.3 0.0 4.3e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBY19737.1 - 3.7e-17 62.3 0.0 7.1e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CBY19737.1 - 1.2e-16 60.5 0.0 2.3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 CBY19737.1 - 1.7e-10 40.9 0.0 4.4e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Aa_trans PF01490.18 CBY19739.1 - 2.6e-08 33.0 0.3 2.7e-08 32.9 0.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ig_mannosidase PF17753.1 CBY19741.1 - 5.2e-09 35.7 0.0 1.8e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Ig-fold domain Borrelia_REV PF03978.13 CBY19741.1 - 0.24 11.3 0.9 0.46 10.4 0.9 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein TMIE PF16038.5 CBY19741.1 - 0.24 11.3 2.9 0.75 9.7 1.5 2.1 2 0 0 2 2 2 0 TMIE protein Phage_GPO PF05929.11 CBY19742.1 - 0.04 13.6 16.6 0.045 13.4 16.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Use1 PF09753.9 CBY19742.1 - 0.065 12.9 18.8 0.072 12.8 18.8 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 UPF0242 PF06785.11 CBY19742.1 - 0.17 12.0 27.1 0.46 10.6 27.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CwsA PF10814.8 CBY19742.1 - 0.51 10.5 3.2 0.76 9.9 3.2 1.3 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA ING PF12998.7 CBY19742.1 - 0.78 10.4 15.7 26 5.5 15.7 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF3584 PF12128.8 CBY19742.1 - 0.85 7.1 22.7 0.97 6.9 22.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.22 CBY19742.1 - 0.9 9.8 25.9 0.69 10.2 11.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ANAPC4 PF12896.7 CBY19742.1 - 1.3 8.5 10.5 0.23 10.9 4.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 FUSC PF04632.12 CBY19742.1 - 2.2 6.7 4.0 2.5 6.5 4.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DHR10 PF18595.1 CBY19742.1 - 2.2 8.3 29.1 1.4 9.0 9.8 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-H PF05837.12 CBY19742.1 - 3.5 8.1 23.7 5.5 7.4 19.5 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.15 CBY19742.1 - 4.6 6.7 14.5 5.1 6.6 14.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nup88 PF10168.9 CBY19742.1 - 5 4.8 17.7 1.1 7.0 14.5 1.5 1 1 0 1 1 1 0 Nuclear pore component DUF4795 PF16043.5 CBY19742.1 - 6.9 6.2 26.0 98 2.5 26.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 CBY19742.1 - 7.2 6.7 14.1 14 5.8 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2951 PF11166.8 CBY19742.1 - 9.7 6.5 17.5 0.47 10.7 3.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) Alg6_Alg8 PF03155.15 CBY19744.1 - 3e-126 422.2 32.9 3.9e-126 421.9 32.9 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyco_hydro_2 PF00703.21 CBY19744.1 - 0.00043 20.9 0.0 0.00085 20.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 ABC_tran PF00005.27 CBY19745.1 - 2.3e-48 164.2 0.0 6.8e-23 81.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CBY19745.1 - 1.8e-23 82.4 0.2 3.3e-23 81.5 0.2 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY19745.1 - 1.2e-15 58.1 7.6 0.00045 20.1 0.0 4.7 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY19745.1 - 2.5e-11 43.4 0.1 0.00065 19.2 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBY19745.1 - 2.2e-08 33.7 0.1 0.0014 18.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY19745.1 - 4.4e-08 33.9 2.0 0.0074 16.8 0.1 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 CBY19745.1 - 5.4e-08 32.9 0.0 0.009 16.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY19745.1 - 1.3e-06 28.7 2.8 0.0027 18.0 0.0 3.4 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CBY19745.1 - 1.5e-06 28.3 0.2 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CBY19745.1 - 7.5e-06 26.4 1.2 0.0067 16.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CBY19745.1 - 1.3e-05 25.0 0.3 0.091 12.5 0.1 3.6 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CBY19745.1 - 2.1e-05 24.8 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CBY19745.1 - 2.4e-05 24.2 0.7 0.077 12.7 0.0 2.9 4 0 0 4 4 3 2 AAA ATPase domain DUF87 PF01935.17 CBY19745.1 - 0.00013 22.1 0.2 0.027 14.5 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 CBY19745.1 - 0.00013 22.0 0.2 0.044 13.8 0.0 2.7 3 0 0 3 3 3 1 Dynamin family AAA_18 PF13238.6 CBY19745.1 - 0.00014 22.4 0.2 0.5 10.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 CBY19745.1 - 0.00021 20.4 0.0 0.54 9.2 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CBY19745.1 - 0.00034 20.6 0.3 0.21 11.5 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 CBY19745.1 - 0.00034 20.4 0.1 0.29 10.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 CBY19745.1 - 0.00039 20.1 0.0 0.55 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CBY19745.1 - 0.00065 19.0 0.0 0.074 12.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 CBY19745.1 - 0.0015 18.7 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBY19745.1 - 0.0016 18.0 0.0 0.22 11.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_ATPase PF09818.9 CBY19745.1 - 0.0077 15.1 0.4 9.9 4.8 0.1 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 CBY19745.1 - 0.0085 16.5 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 CBY19745.1 - 0.0095 15.5 0.5 4.4 6.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 CBY19745.1 - 0.012 15.7 0.1 0.87 9.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 CBY19745.1 - 0.013 15.7 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 CBY19745.1 - 0.019 15.2 1.5 1.8 8.8 0.2 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 CBY19745.1 - 0.026 13.7 0.0 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 CBY19745.1 - 0.027 13.8 0.3 3.5 6.9 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family Arf PF00025.21 CBY19745.1 - 0.028 13.9 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2813 PF11398.8 CBY19745.1 - 0.029 13.7 0.8 1.4 8.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_13 PF13166.6 CBY19745.1 - 0.032 12.9 0.1 5 5.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 CBY19745.1 - 0.038 13.9 0.0 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MobB PF03205.14 CBY19745.1 - 0.047 13.6 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 CBY19745.1 - 0.063 13.7 0.0 19 5.7 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 CBY19745.1 - 0.077 12.3 0.0 5 6.3 0.0 2.2 2 0 0 2 2 2 0 Septin NB-ARC PF00931.22 CBY19745.1 - 0.08 12.1 0.1 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 CBY19745.1 - 0.08 13.0 0.2 14 5.8 0.0 3.3 3 1 1 4 4 4 0 AAA domain NTPase_1 PF03266.15 CBY19745.1 - 0.081 12.8 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 NTPase dNK PF01712.19 CBY19745.1 - 0.088 12.6 0.6 2.2 8.1 0.0 2.5 3 0 0 3 3 2 0 Deoxynucleoside kinase TsaE PF02367.17 CBY19745.1 - 0.093 12.7 0.1 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 CBY19745.1 - 0.32 8.5 1.2 2.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Rap_GAP PF02145.15 CBY19746.1 - 6.6e-18 64.9 0.0 1.7e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP RRM_1 PF00076.22 CBY19747.1 - 1.6e-14 53.4 0.0 2.8e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY19747.1 - 0.057 13.4 0.1 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif UEV PF05743.13 CBY19748.1 - 2.5e-37 127.4 0.0 5e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CBY19748.1 - 1e-21 76.6 0.3 1.5e-20 72.9 0.1 2.2 2 0 0 2 2 2 1 Vps23 core domain FOXP-CC PF16159.5 CBY19748.1 - 0.095 13.3 2.5 1.1 10.0 0.1 2.7 3 0 0 3 3 3 0 FOXP coiled-coil domain DUF4200 PF13863.6 CBY19748.1 - 0.15 12.5 10.4 0.087 13.2 7.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 CBY19748.1 - 0.27 10.5 3.1 0.13 11.5 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Troponin PF00992.20 CBY19748.1 - 0.4 11.0 5.9 0.84 9.9 5.9 1.5 1 0 0 1 1 1 0 Troponin TMPIT PF07851.13 CBY19748.1 - 1.4 8.1 4.8 1 8.5 2.6 1.7 2 0 0 2 2 2 0 TMPIT-like protein Mst1_SARAH PF11629.8 CBY19748.1 - 4.1 7.6 6.6 11 6.2 0.9 2.8 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 UQ_con PF00179.26 CBY19749.1 - 1.9e-09 37.3 0.0 6.1e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY19749.1 - 0.0059 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBY19749.1 - 0.037 14.3 0.0 0.093 13.0 0.0 1.7 1 1 0 1 1 1 0 RWD domain BNIP2 PF12496.8 CBY19749.1 - 0.85 10.1 6.0 1.5 9.3 6.0 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 WD40 PF00400.32 CBY19752.1 - 1.6e-30 104.6 16.9 7.6e-06 26.6 0.4 10.4 9 1 1 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY19752.1 - 1.9e-21 76.1 2.6 6.3e-06 26.4 0.0 7.3 4 3 5 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY19752.1 - 1.4e-11 44.6 0.3 4.9e-06 26.6 0.0 3.7 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY19752.1 - 1.2e-06 28.1 1.7 0.03 13.7 0.6 3.4 2 1 1 3 3 3 2 WD40-like domain NUP214 PF16755.5 CBY19752.1 - 8.1e-05 22.0 0.0 0.015 14.6 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PD40 PF07676.12 CBY19752.1 - 0.00016 21.5 0.1 3.6 7.6 0.0 4.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CBY19752.1 - 0.0063 15.5 0.8 9.8 5.0 0.1 4.2 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY19752.1 - 0.049 12.3 0.0 1.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CBY19752.1 - 0.068 11.7 0.1 0.64 8.5 0.0 2.4 3 0 0 3 3 3 0 Cytochrome D1 heme domain IKI3 PF04762.12 CBY19752.1 - 0.098 10.6 0.0 8.2 4.3 0.0 2.9 3 0 0 3 3 3 0 IKI3 family LVIVD PF08309.11 CBY19752.1 - 0.43 9.9 2.8 0.76 9.1 0.2 2.7 3 0 0 3 3 3 0 LVIVD repeat Shugoshin_N PF07558.11 CBY19753.1 - 0.0018 18.1 3.6 0.0018 18.1 3.6 4.4 5 0 0 5 5 5 1 Shugoshin N-terminal coiled-coil region Seryl_tRNA_N PF02403.22 CBY19753.1 - 0.007 16.6 3.9 0.007 16.6 3.9 5.6 2 1 5 7 7 7 1 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 CBY19753.1 - 0.0088 15.2 23.3 0.0088 15.2 23.3 4.0 2 1 2 4 4 4 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 CBY19753.1 - 0.019 15.2 15.0 0.019 15.2 15.0 4.7 2 1 2 5 5 5 0 Fibrinogen alpha/beta chain family Filament PF00038.21 CBY19753.1 - 0.02 14.5 58.9 0.033 13.8 15.5 3.7 2 1 2 4 4 4 0 Intermediate filament protein APG6_N PF17675.1 CBY19753.1 - 1.1 9.8 63.6 0.11 13.0 23.1 5.2 1 1 3 4 4 4 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 CBY19753.1 - 6.4 6.8 69.1 0.19 11.7 10.1 5.4 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Apolipoprotein PF01442.18 CBY19757.1 - 0.00063 19.7 6.8 0.00063 19.7 6.8 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 CBY19757.1 - 0.023 14.9 7.1 3.1 8.1 0.4 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 CBY19757.1 - 0.26 11.8 21.7 6.2 7.4 0.4 3.4 2 1 0 2 2 2 0 YtxH-like protein Syntaxin_2 PF14523.6 CBY19757.1 - 0.29 11.5 4.8 0.37 11.2 1.0 2.4 2 1 1 3 3 3 0 Syntaxin-like protein DUF4455 PF14643.6 CBY19757.1 - 0.5 9.0 11.6 0.76 8.4 8.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) ApoLp-III PF07464.11 CBY19757.1 - 0.52 10.4 14.5 0.26 11.4 8.2 2.4 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HisKA_3 PF07730.13 CBY19757.1 - 0.78 10.3 2.5 33 5.1 0.0 2.8 3 0 0 3 3 3 0 Histidine kinase AhpC-TSA PF00578.21 CBY19758.1 - 6.1e-35 119.8 0.0 1.1e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY19758.1 - 1.7e-13 50.5 0.0 2.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBY19758.1 - 2.1e-12 46.7 0.1 4.2e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF563 PF04577.14 CBY19758.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF563) MFS_1 PF07690.16 CBY19759.1 - 1.1e-23 83.7 35.8 1.1e-23 83.7 35.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBY19759.1 - 0.00026 19.4 10.0 0.00061 18.2 10.0 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MOSC_N PF03476.16 CBY19760.1 - 6.4e-17 61.5 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 CBY19760.1 - 3.9e-15 56.0 0.0 6e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain Neuroparsin PF07327.11 CBY19760.1 - 0.1 13.1 0.0 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 Neuroparsin adh_short PF00106.25 CBY19761.1 - 7.4e-50 169.1 1.1 9.9e-50 168.7 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY19761.1 - 8.7e-48 162.9 0.2 1.1e-47 162.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY19761.1 - 5e-13 49.3 0.5 7.2e-13 48.8 0.5 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CBY19761.1 - 1.9e-05 24.7 0.2 2.4e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CBY19761.1 - 0.032 13.7 0.1 0.11 12.0 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CBY19761.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MOSC PF03473.17 CBY19762.1 - 6.7e-19 68.2 0.0 9.6e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 CBY19762.1 - 3.5e-17 62.4 0.0 5.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain adh_short PF00106.25 CBY19763.1 - 2.8e-50 170.5 1.0 3.7e-50 170.1 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY19763.1 - 3.2e-47 161.1 0.2 4e-47 160.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY19763.1 - 1e-12 48.4 0.4 1.4e-12 47.9 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CBY19763.1 - 1.8e-05 24.7 0.2 2.2e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CBY19763.1 - 0.026 14.0 0.1 0.078 12.4 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CBY19763.1 - 0.033 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain I-set PF07679.16 CBY19765.1 - 2.8e-66 219.6 0.0 1.8e-20 72.8 0.0 4.0 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY19765.1 - 1.5e-46 156.9 0.1 2.3e-15 57.0 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 CBY19765.1 - 2.4e-31 107.9 0.2 1.2e-13 51.1 0.0 3.9 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 CBY19765.1 - 2.8e-26 91.5 0.0 3.4e-09 36.8 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 CBY19765.1 - 3.1e-15 56.3 0.4 4.6e-05 23.5 0.0 6.2 4 3 1 5 5 5 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY19765.1 - 3.2e-11 43.1 0.0 0.012 15.7 0.0 3.5 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 CBY19765.1 - 2.8e-07 30.5 0.0 0.43 10.6 0.0 3.4 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family C1-set PF07654.15 CBY19765.1 - 2.8e-07 30.8 0.0 1.9 8.9 0.0 4.3 4 0 0 4 4 4 2 Immunoglobulin C1-set domain Ig_4 PF16680.5 CBY19765.1 - 3.9e-06 27.0 0.7 0.35 11.1 0.1 4.3 4 2 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 CBY19765.1 - 4.6e-06 26.6 0.0 0.15 12.1 0.0 3.8 3 1 1 4 4 4 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 CBY19765.1 - 1.2e-05 25.6 0.6 0.29 11.6 0.0 4.7 4 2 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 CBY19765.1 - 0.00012 21.8 0.0 0.26 11.1 0.1 3.5 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 CBY19765.1 - 0.0017 17.9 0.4 3.9 7.1 0.1 3.5 3 0 0 3 3 3 1 Immunoglobulin domain DUF3465 PF11948.8 CBY19765.1 - 0.16 11.8 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3465) I-set PF07679.16 CBY19766.1 - 6.5e-33 112.7 2.5 4.1e-09 36.4 0.5 5.3 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY19766.1 - 3.3e-21 75.7 2.4 1.8e-05 25.2 0.0 5.7 6 0 0 6 6 6 3 Immunoglobulin domain Ig_2 PF13895.6 CBY19766.1 - 2.9e-09 37.1 3.1 0.0056 17.0 0.1 3.8 3 1 1 4 4 4 2 Immunoglobulin domain ig PF00047.25 CBY19766.1 - 5.2e-06 26.5 1.8 0.45 10.7 0.0 4.3 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 CBY19766.1 - 2.9e-05 24.2 3.8 0.14 12.4 0.5 4.9 3 2 0 3 3 3 1 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CBY19766.1 - 0.0094 16.0 0.3 0.54 10.3 0.0 3.2 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain I-set PF07679.16 CBY19768.1 - 4.6e-86 283.0 21.4 2e-11 43.8 0.1 13.2 13 0 0 13 13 13 12 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY19768.1 - 2.2e-56 188.4 0.2 4.6e-06 27.1 0.0 12.5 12 0 0 12 12 12 9 Immunoglobulin domain ig PF00047.25 CBY19768.1 - 1.3e-32 111.8 13.0 1.3e-06 28.5 0.1 12.0 13 1 0 13 13 12 7 Immunoglobulin domain Ig_2 PF13895.6 CBY19768.1 - 4.7e-22 78.1 5.2 0.21 12.0 0.0 10.2 10 0 0 10 10 10 6 Immunoglobulin domain V-set PF07686.17 CBY19768.1 - 3.1e-14 53.1 6.1 0.43 10.8 0.0 10.7 10 4 0 10 10 10 4 Immunoglobulin V-set domain fn3 PF00041.21 CBY19768.1 - 2.4e-08 34.2 0.0 1.2e-07 32.0 0.0 2.2 1 0 0 1 1 1 1 Fibronectin type III domain Ig_6 PF18452.1 CBY19768.1 - 3.6e-08 32.8 0.0 0.23 11.0 0.0 5.6 6 0 0 6 6 6 2 Immunoglobulin domain Ig_5 PF16681.5 CBY19768.1 - 3.8e-05 24.0 10.2 2.2 8.7 0.0 7.1 8 0 0 8 8 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CBY19768.1 - 0.00019 21.7 13.7 25 5.2 0.0 7.3 8 0 0 8 8 6 0 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 CBY19768.1 - 0.00083 19.5 0.4 36 4.6 0.0 5.6 7 0 0 7 7 6 0 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 CBY19768.1 - 0.0019 18.3 0.1 44 4.2 0.0 4.7 4 0 0 4 4 4 0 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 CBY19768.1 - 0.0039 17.2 0.0 3.9 7.6 0.0 4.3 5 0 0 5 5 5 1 Penicillin-Binding Protein C-terminus Family SH3_1 PF00018.28 CBY19768.1 - 0.085 12.5 1.4 0.26 10.9 1.4 1.8 1 0 0 1 1 1 0 SH3 domain Phospholip_A2_1 PF00068.19 CBY19769.1 - 3.7e-14 53.1 7.1 3.7e-14 53.1 7.1 1.8 2 0 0 2 2 2 1 Phospholipase A2 Pkinase PF00069.25 CBY19770.1 - 1.4e-08 34.5 0.1 2.8e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19770.1 - 7.6e-07 28.7 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.6 CBY19770.1 - 0.12 12.5 2.8 11 6.3 0.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) ABC2_membrane PF01061.24 CBY19771.1 - 8.5e-42 142.9 26.0 1.3e-41 142.4 26.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBY19771.1 - 8.1e-22 78.2 0.1 1.2e-21 77.7 0.1 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBY19771.1 - 1.2e-05 24.9 0.1 1.7e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBY19771.1 - 1.3e-05 25.2 0.6 0.062 13.1 0.3 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CBY19771.1 - 0.096 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY19771.1 - 0.2 11.4 0.1 0.4 10.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain I-set PF07679.16 CBY19776.1 - 8.7e-23 80.2 0.7 5.2e-15 55.3 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY19776.1 - 2.1e-21 76.3 5.7 2.1e-12 47.4 0.0 5.1 4 1 1 5 5 5 3 Immunoglobulin domain ig PF00047.25 CBY19776.1 - 8.5e-13 48.3 3.2 6.2e-07 29.5 0.0 4.6 5 0 0 5 5 5 2 Immunoglobulin domain Ig_2 PF13895.6 CBY19776.1 - 8.2e-12 45.3 7.7 1.5e-09 38.1 0.0 4.3 5 0 0 5 5 5 1 Immunoglobulin domain V-set PF07686.17 CBY19776.1 - 6.4e-10 39.2 1.4 0.00052 20.2 0.0 4.8 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY19776.1 - 1.1e-06 28.0 0.1 0.0035 16.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 CBY19776.1 - 0.00029 20.8 1.1 0.0012 18.9 0.0 2.5 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 CBY19776.1 - 0.0074 16.3 0.0 0.31 11.1 0.0 3.1 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 CBY19776.1 - 0.028 14.6 0.2 0.27 11.4 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Ig_4 PF16680.5 CBY19776.1 - 0.14 12.5 2.8 2.6 8.4 0.0 3.9 4 0 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Glutaminase PF04960.15 CBY19777.1 - 6e-115 383.3 0.0 7.7e-115 383.0 0.0 1.1 1 0 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 CBY19777.1 - 4.6e-14 52.5 0.2 1.5e-13 50.9 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain Ank_4 PF13637.6 CBY19777.1 - 4.6e-11 43.0 0.0 2.3e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY19777.1 - 2.5e-10 40.8 0.0 5.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY19777.1 - 1.4e-07 31.6 0.2 4.5e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY19777.1 - 9.1e-05 22.6 0.0 0.0058 17.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 CBY19777.1 - 0.0049 17.3 0.0 0.091 13.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Hormone_recep PF00104.30 CBY19778.1 - 0.0013 18.4 0.2 0.0077 15.8 0.0 2.1 1 1 1 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Trypsin PF00089.26 CBY19780.1 - 1e-32 113.7 0.5 7e-17 62.0 0.0 2.6 2 1 1 3 3 3 2 Trypsin DUF316 PF03761.15 CBY19780.1 - 0.00011 21.8 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DUF4568 PF15132.6 CBY19780.1 - 0.17 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) Cadherin PF00028.17 CBY19781.1 - 0.089 13.2 0.2 0.14 12.6 0.2 1.5 1 1 0 1 1 1 0 Cadherin domain Plectin PF00681.20 CBY19782.1 - 1.8e-25 88.5 0.1 3.9e-09 36.2 0.0 4.2 3 1 1 4 4 4 3 Plectin repeat Forkhead PF00250.18 CBY19783.1 - 9.9e-18 64.2 0.3 1.8e-16 60.1 0.0 2.3 2 0 0 2 2 2 1 Forkhead domain FlgO PF17680.1 CBY19783.1 - 0.044 13.5 0.1 0.08 12.7 0.1 1.5 1 0 0 1 1 1 0 FlgO protein Spectrin PF00435.21 CBY19784.1 - 1.2e-32 112.5 162.2 4e-11 43.3 1.3 21.5 17 4 4 23 23 23 12 Spectrin repeat GAS2 PF02187.17 CBY19784.1 - 4.8e-31 106.7 0.3 1.4e-30 105.1 0.3 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_1 PF00036.32 CBY19784.1 - 5.4e-07 28.7 0.2 0.00022 20.5 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY19784.1 - 4.1e-06 27.1 0.6 4.1e-06 27.1 0.6 5.0 6 0 0 6 6 6 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY19784.1 - 6.2e-06 25.7 0.1 0.00014 21.5 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBY19784.1 - 0.006 16.4 0.2 0.034 14.0 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair Pkinase PF00069.25 CBY19785.1 - 3.3e-70 236.5 0.0 3.8e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19785.1 - 4.4e-35 121.2 0.0 5.5e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY19785.1 - 0.00013 21.0 0.0 0.00044 19.3 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY19785.1 - 0.0031 17.5 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY19785.1 - 0.02 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 CBY19785.1 - 0.15 11.4 0.0 0.36 10.1 0.0 1.7 2 1 0 2 2 2 0 Kinase-like RhoGEF PF00621.20 CBY19786.1 - 2e-39 135.7 1.0 3.2e-39 135.0 1.0 1.3 1 0 0 1 1 1 1 RhoGEF domain AAA_33 PF13671.6 CBY19787.1 - 1.1e-17 64.5 0.1 2.9e-17 63.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain SPRY PF00622.28 CBY19787.1 - 4.9e-10 39.6 0.0 1.6e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 SPRY domain HeH PF12949.7 CBY19787.1 - 4.5e-08 32.7 2.3 7.5e-08 32.0 0.9 2.1 2 0 0 2 2 2 1 HeH/LEM domain KTI12 PF08433.10 CBY19787.1 - 0.0018 17.8 2.1 0.0036 16.8 1.5 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CBY19787.1 - 0.027 15.0 0.2 0.11 13.0 0.2 2.1 1 0 0 1 1 1 0 AAA domain SAP PF02037.27 CBY19787.1 - 0.059 13.1 0.4 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 SAP domain Roc PF08477.13 CBY19787.1 - 0.064 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase HSP90 PF00183.18 CBY19788.1 - 3.2e-98 329.9 10.5 1.6e-95 321.0 6.6 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CBY19788.1 - 2.9e-12 46.6 0.1 5.7e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBY19788.1 - 1.5e-08 35.1 0.1 3.1e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Exo5 PF09810.9 CBY19788.1 - 0.073 12.5 0.7 0.11 11.9 0.7 1.3 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease BRCA-2_helical PF09169.10 CBY19789.1 - 0.12 12.1 2.3 0.23 11.1 2.3 1.4 1 0 0 1 1 1 0 BRCA2, helical DUF1955 PF09205.10 CBY19790.1 - 0.042 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) PDH_E1_M PF17831.1 CBY19790.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain PDZ_6 PF17820.1 CBY19791.1 - 1.3e-07 31.4 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY19791.1 - 2.7e-05 24.4 0.0 6.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY19791.1 - 6.5e-05 23.2 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.25 CBY19792.1 - 1.3e-64 218.1 0.0 1.9e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19792.1 - 7.4e-34 117.2 0.0 1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1908 PF08926.11 CBY19792.1 - 7.5e-25 87.6 0.1 1.3e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1908) APH PF01636.23 CBY19792.1 - 4.2e-06 26.9 0.0 0.028 14.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY19792.1 - 4.8e-06 26.1 0.5 0.00037 19.9 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY19792.1 - 7.2e-05 22.2 0.2 0.00013 21.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY19792.1 - 0.00015 20.9 0.2 0.00057 18.9 0.2 1.8 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CBY19792.1 - 0.0033 17.1 0.1 0.05 13.2 0.0 2.4 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CBY19792.1 - 0.004 16.8 0.8 0.013 15.1 0.4 2.0 1 1 1 2 2 2 1 RIO1 family EF-hand_6 PF13405.6 CBY19794.1 - 3.6e-09 35.8 7.0 6.7e-05 22.5 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY19794.1 - 1.1e-08 35.4 6.9 1.5e-07 31.8 4.9 3.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY19794.1 - 2e-08 33.2 12.6 0.00016 21.0 0.2 3.4 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 CBY19794.1 - 0.00044 20.5 0.1 0.059 13.7 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 CBY19794.1 - 0.007 16.2 4.9 0.012 15.4 2.8 2.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY19794.1 - 0.57 9.8 11.0 1.4 8.6 0.3 3.5 4 0 0 4 4 4 0 EF hand Collagen PF01391.18 CBY19795.1 - 1.5e-42 143.1 168.3 8e-09 35.1 30.6 7.1 2 1 3 5 5 5 4 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY19795.1 - 3.3e-39 134.9 0.4 3e-15 56.9 0.0 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 CBY19795.1 - 1.3e-24 86.9 2.7 3.9e-10 40.3 0.1 3.7 4 0 0 4 4 4 3 von Willebrand factor type A domain Copine PF07002.16 CBY19795.1 - 5.5e-05 22.7 0.4 0.0029 17.1 0.1 2.7 3 0 0 3 3 3 1 Copine CobN-Mg_chel PF02514.16 CBY19795.1 - 0.00086 17.2 0.0 0.0014 16.5 0.0 1.3 1 0 0 1 1 1 1 CobN/Magnesium Chelatase VWA_CoxE PF05762.14 CBY19795.1 - 0.0074 15.7 0.3 0.86 8.9 0.1 2.6 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 CBY19795.1 - 0.25 11.4 1.6 3.6 7.7 0.2 3.0 3 1 1 4 4 4 0 vWA found in TerF C terminus LRR_8 PF13855.6 CBY19797.1 - 7e-08 32.1 3.5 2.1e-07 30.6 3.5 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 CBY19797.1 - 1.5e-05 25.3 2.9 1.6e-05 25.1 1.6 1.8 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) CD34_antigen PF06365.12 CBY19797.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family PTP_tm PF18861.1 CBY19797.1 - 0.087 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 CBY19797.1 - 0.11 13.4 0.0 0.2 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Chromo_shadow PF01393.19 CBY19798.1 - 4.4e-24 84.3 0.5 1.6e-23 82.6 0.1 2.1 3 0 0 3 3 3 1 Chromo shadow domain Chromo PF00385.24 CBY19798.1 - 8.8e-16 57.6 6.7 3.6e-13 49.2 0.7 2.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1918 PF08940.11 CBY19798.1 - 0.13 11.9 0.0 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Ras PF00071.22 CBY19799.1 - 6.4e-53 178.7 0.0 7.3e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY19799.1 - 3.8e-19 69.1 0.0 5.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY19799.1 - 7.1e-07 28.8 0.0 9.6e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY19799.1 - 0.015 14.8 0.1 0.089 12.3 0.1 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain GPHH PF16905.5 CBY19800.1 - 5.7e-31 106.0 0.1 1.1e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 CBY19800.1 - 8.7e-28 96.4 0.1 1.6e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain Ion_trans PF00520.31 CBY19800.1 - 1.9e-09 37.1 0.0 2.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CBY19800.1 - 0.0016 17.2 3.7 0.0023 16.7 3.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CBY19801.1 - 1.3e-184 610.7 79.5 3.9e-64 216.2 5.3 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CBY19801.1 - 1.6e-06 27.1 8.7 1.6e-06 27.1 8.7 8.4 6 3 3 9 9 9 6 Polycystin cation channel LRR_8 PF13855.6 CBY19802.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Leucine rich repeat Actin PF00022.19 CBY19804.1 - 6.7e-115 384.0 0.0 4.9e-114 381.1 0.0 1.8 1 1 0 1 1 1 1 Actin Trypsin PF00089.26 CBY19805.1 - 2.4e-36 125.6 4.9 6.5e-33 114.4 4.9 2.9 1 1 0 1 1 1 1 Trypsin Neur_chan_LBD PF02931.23 CBY19806.1 - 1.3e-39 135.8 0.0 1.8e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY19806.1 - 2.9e-17 63.5 12.5 5.7e-11 42.9 2.0 3.0 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region zf-CCCH PF00642.24 CBY19807.1 - 7.7e-40 134.1 38.5 1.4e-09 37.6 2.9 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBY19807.1 - 5e-20 70.8 38.6 1.9e-06 27.5 2.9 5.3 5 0 0 5 5 5 5 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY19807.1 - 1.3e-18 66.4 46.4 1.1e-06 28.5 1.3 5.4 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH_2 PF14608.6 CBY19807.1 - 4.4e-06 27.0 33.2 0.085 13.4 0.5 5.5 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CBY19807.1 - 9.3e-06 26.3 27.0 0.27 11.9 0.8 5.2 3 1 2 5 5 5 4 Torus domain Defensin_int PF17858.1 CBY19807.1 - 8.2 6.5 10.0 30 4.7 0.5 3.7 4 0 0 4 4 4 0 Platypus intermediate defensin-like peptide UQ_con PF00179.26 CBY19808.1 - 3.6e-53 179.0 0.0 4.1e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY19808.1 - 0.0041 16.8 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBY19808.1 - 0.0051 17.1 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 CBY19808.1 - 0.07 13.0 0.2 0.12 12.2 0.2 1.4 1 1 0 1 1 1 0 UEV domain Ribosomal_L14e PF01929.17 CBY19809.1 - 2.2e-25 89.0 1.2 2.8e-25 88.6 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 P34-Arc PF04045.14 CBY19810.1 - 2.2e-86 289.5 0.1 2.6e-86 289.2 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 CBY19810.1 - 0.0047 16.6 0.2 0.022 14.4 0.2 2.0 2 1 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF1930 PF09122.10 CBY19810.1 - 0.067 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) TFIIE_beta PF02186.15 CBY19811.1 - 6.3e-09 36.0 0.1 4e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 CBY19811.1 - 0.00052 19.6 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 Antimicrobial_8 PF08103.11 CBY19811.1 - 0.014 15.5 2.5 1.7 8.9 0.1 2.9 2 0 0 2 2 2 0 Uperin family NPHI_C PF08469.10 CBY19811.1 - 0.036 14.0 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal Imm12 PF15560.6 CBY19811.1 - 0.071 13.1 0.1 0.61 10.0 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 12 Serinc PF03348.15 CBY19812.1 - 2e-147 491.6 13.3 2.3e-147 491.4 13.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3671 PF12420.8 CBY19812.1 - 1 9.5 5.1 1.2e+02 2.8 5.8 3.3 3 2 0 3 3 3 0 Protein of unknown function Phage_Nu1 PF07471.12 CBY19814.1 - 0.021 14.6 0.7 0.025 14.4 0.7 1.1 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 tRNA-synt_1g PF09334.11 CBY19815.1 - 1.9e-73 247.5 1.8 2.2e-45 155.1 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CBY19815.1 - 2.3e-16 59.2 1.7 8e-10 37.6 0.0 2.7 2 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CBY19815.1 - 4.3e-09 36.2 0.1 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CBY19815.1 - 0.04 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF2523 PF10734.9 CBY19815.1 - 0.23 12.1 0.0 0.59 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) OrsD PF12013.8 CBY19817.1 - 0.02 15.3 0.3 0.04 14.4 0.3 1.5 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D JAB PF01398.21 CBY19818.1 - 5.9e-31 106.9 0.0 9.1e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CBY19818.1 - 1.9e-26 92.7 0.0 3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Sulfatase PF00884.23 CBY19819.1 - 1.2e-61 208.8 0.1 1.5e-61 208.5 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY19819.1 - 1.1e-07 31.8 0.6 7.3e-07 29.1 0.6 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 CBY19819.1 - 0.0031 18.2 0.0 0.01 16.6 0.0 1.8 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 CBY19819.1 - 0.0067 15.1 0.0 0.0096 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 CBY19819.1 - 0.009 15.9 0.1 0.055 13.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function RWD PF05773.22 CBY19821.1 - 1.1e-06 28.9 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain Pkinase PF00069.25 CBY19822.1 - 2.1e-49 168.2 0.1 3.2e-48 164.4 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19822.1 - 2.3e-28 99.2 0.0 1.2e-27 96.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY19822.1 - 0.048 13.0 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CBY19822.1 - 0.1 12.5 0.4 0.95 9.3 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 CBY19823.1 - 6.1e-09 36.1 8.7 1e-08 35.3 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY19823.1 - 1.9e-08 34.0 5.9 4.9e-08 32.7 6.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY19823.1 - 1.3e-07 31.5 2.6 6.7e-07 29.2 2.9 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY19823.1 - 9e-07 28.8 9.5 1.5e-06 28.1 9.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY19823.1 - 5.6e-06 26.1 8.2 1.1e-05 25.2 8.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CBY19823.1 - 2.3e-05 23.9 1.5 2.7e-05 23.7 1.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.6 CBY19823.1 - 3.5e-05 23.5 9.7 5.3e-05 22.9 9.7 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CBY19823.1 - 8.3e-05 22.2 2.8 8.3e-05 22.2 2.8 1.8 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 CBY19823.1 - 0.00027 20.7 6.7 0.0008 19.2 6.8 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 CBY19823.1 - 0.00059 19.9 8.0 0.0061 16.7 8.0 2.0 1 1 0 1 1 1 1 FYVE zinc finger DUF1272 PF06906.11 CBY19823.1 - 0.0013 18.7 8.3 0.0019 18.3 8.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 CBY19823.1 - 0.0042 17.2 11.5 0.028 14.6 9.8 2.8 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING DZR PF12773.7 CBY19823.1 - 0.0073 16.3 9.3 0.0077 16.2 4.2 2.2 1 1 1 2 2 2 1 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 CBY19823.1 - 0.2 11.7 9.3 3 8.0 0.1 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-HYPF PF07503.12 CBY19823.1 - 0.75 9.6 0.2 0.75 9.6 0.2 3.5 4 0 0 4 4 4 0 HypF finger zinc_ribbon_4 PF13717.6 CBY19823.1 - 1.1 9.2 9.8 2.5 8.1 0.4 3.5 3 1 1 4 4 4 0 zinc-ribbon domain zf-MYND PF01753.18 CBY19823.1 - 1.5 9.0 9.0 7.1 6.8 0.7 2.2 2 0 0 2 2 2 0 MYND finger IBR PF01485.21 CBY19823.1 - 2.5 8.4 11.3 54 4.1 11.2 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-rbx1 PF12678.7 CBY19823.1 - 3.4 8.0 9.3 17 5.8 9.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Peptidase_M20 PF01546.28 CBY19824.1 - 9.2e-37 126.7 0.0 1.5e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBY19824.1 - 7.1e-16 58.1 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Antibiotic_NAT PF02522.14 CBY19824.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase Peptidase_M28 PF04389.17 CBY19824.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Fur_reg_FbpB PF13040.6 CBY19824.1 - 0.14 11.7 0.2 0.35 10.5 0.2 1.7 1 0 0 1 1 1 0 Fur-regulated basic protein B Aminotran_3 PF00202.21 CBY19825.1 - 5.8e-105 351.3 0.0 7e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FadR_C PF07840.12 CBY19825.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 FadR C-terminal domain Galactosyl_T PF01762.21 CBY19826.1 - 8.2e-22 78.0 0.4 3e-20 72.9 0.0 3.0 2 1 0 2 2 2 1 Galactosyltransferase SAUGI PF06106.11 CBY19826.1 - 0.024 15.1 0.9 0.12 12.9 0.1 2.5 4 0 0 4 4 4 0 S. aureus uracil DNA glycosylase inhibitor Cadherin PF00028.17 CBY19827.1 - 3.9e-48 161.9 5.9 2.1e-12 47.3 0.0 7.0 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CBY19827.1 - 8.5e-07 28.7 0.6 0.0094 15.8 0.1 4.3 3 1 0 3 3 3 2 Cadherin-like Shisa PF13908.6 CBY19827.1 - 0.01 16.1 0.4 0.072 13.3 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Mucin PF01456.17 CBY19827.1 - 0.015 15.3 0.3 0.031 14.3 0.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Comm PF15957.5 CBY19827.1 - 0.03 14.6 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 Commissureless EphA2_TM PF14575.6 CBY19827.1 - 0.038 14.9 0.0 0.083 13.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.6 CBY19827.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 FAM163 family Adeno_E3_CR2 PF02439.15 CBY19827.1 - 0.17 11.7 3.2 0.4 10.5 3.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Helo_like_N PF17111.5 CBY19828.1 - 0.0081 15.6 1.6 0.01 15.2 1.6 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins bZIP_1 PF00170.21 CBY19828.1 - 0.061 13.4 8.0 0.24 11.5 3.2 2.2 1 1 1 2 2 2 0 bZIP transcription factor Phlebovirus_G1 PF07243.11 CBY19828.1 - 0.1 10.9 1.1 0.14 10.6 1.1 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Seryl_tRNA_N PF02403.22 CBY19828.1 - 0.64 10.3 6.9 0.7 10.1 5.3 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 CBY19828.1 - 1.3 9.5 9.0 10 6.6 9.0 2.1 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 CBY19828.1 - 8.1 6.6 9.3 1.1 9.4 2.8 2.5 1 1 2 3 3 3 0 Basic region leucine zipper Dabb PF07876.12 CBY19829.1 - 6.1 7.5 7.2 5.3 7.7 0.5 4.5 3 0 0 3 3 3 0 Stress responsive A/B Barrel Domain bZIP_1 PF00170.21 CBY19830.1 - 8.6e-14 51.4 12.5 2e-13 50.2 12.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY19830.1 - 2.2e-06 27.7 22.1 9.3e-06 25.6 17.9 3.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY19830.1 - 4.1e-06 27.2 14.1 4.1e-06 27.2 14.1 2.3 2 1 0 2 2 2 1 bZIP Maf transcription factor DUF3793 PF12672.7 CBY19830.1 - 0.044 13.8 0.9 0.079 13.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) WDCP PF15390.6 CBY19830.1 - 0.12 10.7 8.1 0.15 10.4 8.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family YabA PF06156.13 CBY19830.1 - 0.23 12.1 6.4 0.13 12.9 2.9 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 CBY19830.1 - 2.9 8.0 16.5 3.9e+02 1.2 16.3 2.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 CBY19830.1 - 4 7.5 16.6 1.8 8.6 12.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMCO5 PF14992.6 CBY19830.1 - 6.9 6.1 11.2 9.7 5.7 10.1 1.7 1 1 1 2 2 2 0 TMCO5 family CDK2AP PF09806.9 CBY19832.1 - 5.2e-20 72.5 1.6 6.4e-20 72.2 1.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein PRKG1_interact PF15898.5 CBY19832.1 - 0.00052 20.9 6.2 0.59 11.1 0.0 2.2 2 0 0 2 2 2 2 cGMP-dependent protein kinase interacting domain AIP3 PF03915.13 CBY19832.1 - 0.0012 18.0 2.2 0.0015 17.7 2.2 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1887 PF09002.11 CBY19832.1 - 0.0046 15.7 0.9 0.0054 15.5 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) Striatin PF08232.12 CBY19832.1 - 0.012 16.3 7.7 0.015 15.9 7.7 1.1 1 0 0 1 1 1 0 Striatin family DUF3365 PF11845.8 CBY19832.1 - 0.024 15.0 2.9 0.028 14.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) DUF2203 PF09969.9 CBY19832.1 - 1.2 9.9 5.0 1.1 10.0 3.4 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Presenilin PF01080.17 CBY19832.1 - 2.6 6.7 3.7 2.5 6.8 3.7 1.1 1 0 0 1 1 1 0 Presenilin Cdh1_DBD_1 PF18196.1 CBY19832.1 - 5 7.5 7.9 5.9 7.2 7.2 1.6 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Chromo_shadow PF01393.19 CBY19833.1 - 1.1e-11 44.6 1.1 2e-11 43.8 1.1 1.3 1 0 0 1 1 1 1 Chromo shadow domain Chromo PF00385.24 CBY19834.1 - 1.2e-16 60.4 1.6 1.9e-16 59.7 0.5 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CBY19834.1 - 0.017 15.0 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.6 CBY19834.1 - 0.073 13.3 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Ly49 PF08391.10 CBY19834.1 - 2.7 8.4 5.4 25 5.3 0.1 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Ribonuc_red_sm PF00268.21 CBY19835.1 - 1.2e-115 385.7 2.0 1.9e-115 385.2 2.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain CCDC-167 PF15188.6 CBY19835.1 - 0.0065 16.8 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Polo_box_3 PF18544.1 CBY19835.1 - 0.064 13.9 1.2 0.2 12.3 0.1 2.3 3 0 0 3 3 3 0 Polo box domain SMC_N PF02463.19 CBY19836.1 - 3.6e-26 92.0 58.2 5.9e-24 84.7 56.9 3.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBY19836.1 - 1.7e-22 79.9 0.0 6.8e-22 78.0 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBY19836.1 - 4.6e-06 26.7 0.4 4.6e-06 26.7 0.4 3.6 3 3 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Clathrin_bdg PF15045.6 CBY19837.1 - 0.07 13.1 1.9 0.22 11.6 0.1 2.7 2 1 1 3 3 3 0 Clathrin-binding box of Aftiphilin, vesicle trafficking EcsC PF12787.7 CBY19837.1 - 0.081 12.6 4.7 0.44 10.2 0.8 2.3 2 0 0 2 2 2 0 EcsC protein family Aa_trans PF01490.18 CBY19838.1 - 2.4e-11 43.0 28.6 5.3e-06 25.4 3.0 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBY19838.1 - 3.9e-06 26.2 33.3 0.00012 21.3 4.6 2.7 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family Phage_holin_3_6 PF07332.11 CBY19838.1 - 0.42 10.7 0.0 0.42 10.7 0.0 3.9 5 0 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III TRP PF06011.12 CBY19839.1 - 0.055 12.2 0.1 0.057 12.1 0.1 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Anoctamin PF04547.12 CBY19839.1 - 0.074 11.9 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel EGF_CA PF07645.15 CBY19840.1 - 4e-20 71.7 57.6 9.7e-10 38.5 10.7 4.2 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.7 CBY19840.1 - 1.3e-13 50.5 18.4 2.1e-05 24.3 1.7 4.0 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY19840.1 - 1.3e-12 47.7 54.7 1.8e-06 28.0 8.3 5.2 5 0 0 5 5 5 3 EGF domain EGF PF00008.27 CBY19840.1 - 2.5e-11 43.7 36.5 1.8e-05 24.9 5.1 4.1 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 CBY19840.1 - 2.6e-06 27.8 33.7 0.0019 18.7 2.9 4.2 4 0 0 4 4 4 3 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY19840.1 - 1e-05 25.7 35.0 0.036 14.4 5.9 4.8 3 2 1 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY19840.1 - 0.0005 20.1 38.2 0.25 11.4 6.2 3.8 3 0 0 3 3 3 3 MSP1 EGF domain 1 Mucin PF01456.17 CBY19840.1 - 0.83 9.6 15.1 0.085 12.8 9.8 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 CBY19840.1 - 4.4 7.3 9.2 12 5.9 9.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CBY19840.1 - 6.9 4.5 5.6 10 3.9 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sulfotransfer_1 PF00685.27 CBY19841.1 - 3.2e-26 92.4 0.2 1e-25 90.7 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY19841.1 - 4.8e-08 33.6 0.0 1.4e-05 25.6 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_4 PF17784.1 CBY19841.1 - 0.00046 20.1 0.0 0.0062 16.4 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Pkinase PF00069.25 CBY19843.1 - 2.3e-71 240.3 0.0 4e-71 239.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY19843.1 - 1.1e-44 152.7 0.0 1.5e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY19843.1 - 1.9e-08 33.5 0.0 5.9e-08 31.9 0.0 1.6 1 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CBY19843.1 - 1.2e-07 31.3 0.1 2.2e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3543 PF12063.8 CBY19843.1 - 6.9e-07 28.9 0.1 1.4e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) RIO1 PF01163.22 CBY19843.1 - 3.2e-06 26.9 0.1 5.7e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY19843.1 - 3.7e-05 23.8 0.0 9.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Vta1 PF04652.16 CBY19843.1 - 0.0082 16.1 0.2 0.02 14.9 0.2 1.7 1 0 0 1 1 1 1 Vta1 like Haspin_kinase PF12330.8 CBY19843.1 - 0.015 14.3 0.4 0.033 13.1 0.4 1.6 1 1 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CBY19843.1 - 0.029 13.9 0.2 0.094 12.2 0.1 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SSXT PF05030.12 CBY19843.1 - 0.053 13.2 1.9 0.1 12.3 0.3 2.2 2 0 0 2 2 2 0 SSXT protein (N-terminal region) Choline_kinase PF01633.20 CBY19843.1 - 0.066 12.8 0.0 0.57 9.7 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase SesA PF17107.5 CBY19843.1 - 0.12 12.6 0.1 11 6.3 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Pap_E4 PF02711.14 CBY19843.1 - 1.5 9.8 5.9 1.3 10.1 0.1 2.6 2 0 0 2 2 2 0 E4 protein UQ_con PF00179.26 CBY19844.1 - 7.7e-10 38.6 1.0 1.4e-09 37.7 1.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CBY19844.1 - 0.016 15.1 0.2 0.082 12.8 0.1 2.0 2 0 0 2 2 2 0 UEV domain gp45-slide_C PF09116.10 CBY19844.1 - 0.14 12.3 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal DivIC PF04977.15 CBY19844.1 - 0.24 11.2 1.7 0.46 10.3 1.7 1.5 1 0 0 1 1 1 0 Septum formation initiator UQ_con PF00179.26 CBY19845.1 - 0.00018 21.2 0.2 0.00029 20.5 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY19845.1 - 0.05 13.9 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 CBY19845.1 - 0.12 12.2 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 UEV domain DUF2627 PF11118.8 CBY19846.1 - 0.061 13.9 2.0 0.061 13.9 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) CUB PF00431.20 CBY19847.1 - 6.7e-17 61.8 0.0 1.4e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 CUB domain Trypsin PF00089.26 CBY19847.1 - 1.2e-07 31.8 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CBY19848.1 - 5.6e-47 160.4 0.7 5.7e-45 153.8 0.1 2.5 2 0 0 2 2 2 2 Trypsin TSP_1 PF00090.19 CBY19848.1 - 7e-42 141.4 93.9 1.1e-08 35.2 5.9 7.2 6 0 0 6 6 6 6 Thrombospondin type 1 domain Pentaxin PF00354.17 CBY19848.1 - 8.1e-18 64.8 0.7 2.7e-12 46.8 0.0 4.0 4 1 0 4 4 4 2 Pentaxin family Laminin_G_3 PF13385.6 CBY19848.1 - 3.7e-15 56.4 0.0 1.3e-06 28.6 0.0 3.0 2 1 1 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily CUB PF00431.20 CBY19848.1 - 4e-14 52.9 0.3 1.8e-12 47.6 0.1 2.7 1 1 1 2 2 2 1 CUB domain Tektin PF03148.14 CBY19849.1 - 7.2e-141 469.4 36.8 8.6e-141 469.1 36.8 1.1 1 0 0 1 1 1 1 Tektin family Exonuc_VII_L PF02601.15 CBY19849.1 - 0.17 11.4 23.0 0.98 8.9 10.1 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Mit_KHE1 PF10173.9 CBY19849.1 - 0.51 10.4 4.9 1.4 9.0 4.9 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related BLOC1_2 PF10046.9 CBY19849.1 - 3.4 8.0 13.2 0.25 11.7 0.4 3.9 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG5 PF10392.9 CBY19849.1 - 5.7 7.1 14.3 0.17 12.1 0.4 3.3 4 0 0 4 4 4 0 Golgi transport complex subunit 5 NPV_P10 PF05531.12 CBY19849.1 - 9.6 6.8 9.5 7.4 7.1 1.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TMEM232 PF15877.5 CBY19850.1 - 7.3e-07 28.5 0.7 1.2e-06 27.8 0.7 1.3 1 0 0 1 1 1 1 Transmembrane protein family 232 Abhydrolase_3 PF07859.13 CBY19851.1 - 1.7e-09 37.9 0.1 1.9e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CBY19852.1 - 2.5e-30 105.9 0.0 3.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CBY19852.1 - 9.3e-08 31.4 0.3 5.5e-07 28.8 0.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY19854.1 - 2.1e-41 142.1 0.3 7.8e-30 104.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 CBY19854.1 - 2e-07 30.3 0.2 1e-06 28.0 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Maelstrom PF13017.6 CBY19855.1 - 1.8e-21 76.8 2.7 3.4e-21 75.9 2.7 1.4 1 0 0 1 1 1 1 piRNA pathway germ-plasm component zf-NPL4 PF05020.15 CBY19855.1 - 0.012 15.8 1.1 0.012 15.8 1.1 2.0 2 0 0 2 2 2 0 NPL4 family, putative zinc binding region zf-C2H2_4 PF13894.6 CBY19856.1 - 0.0004 21.0 24.5 0.019 15.8 1.1 3.9 3 1 1 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY19856.1 - 0.0011 19.2 19.6 0.11 12.8 2.9 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CBY19856.1 - 0.0019 18.6 20.7 0.087 13.3 0.6 3.7 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 CBY19856.1 - 0.13 12.7 16.2 0.37 11.3 1.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY19856.1 - 0.46 10.8 16.6 11 6.5 8.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 CBY19856.1 - 2.2 8.0 17.2 5.2 6.7 1.8 3.2 3 0 0 3 3 3 0 MYST family zinc finger domain EBV-NA3 PF05009.12 CBY19857.1 - 1.3 8.5 6.8 14 5.1 0.1 2.7 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF2721 PF11026.8 CBY19860.1 - 0.058 13.3 4.5 0.17 11.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) ECH_1 PF00378.20 CBY19861.1 - 1.3e-54 185.2 0.0 1.5e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY19861.1 - 3.9e-13 49.6 0.0 4.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4889 PF16230.5 CBY19861.1 - 0.0026 17.9 0.3 0.037 14.3 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4889) Peptidase_S49 PF01343.18 CBY19861.1 - 0.0035 17.3 0.4 0.47 10.4 0.0 2.7 2 1 0 3 3 3 1 Peptidase family S49 Carboxyl_trans PF01039.22 CBY19861.1 - 0.062 11.9 0.3 0.86 8.2 0.3 2.0 1 1 1 2 2 2 0 Carboxyl transferase domain T3SS_basalb_I PF17001.5 CBY19861.1 - 0.083 13.5 0.2 0.25 12.0 0.1 1.8 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI ANAPC4_WD40 PF12894.7 CBY19862.1 - 0.00055 20.2 0.0 0.047 14.0 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CBY19862.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like PDCD2_C PF04194.13 CBY19863.1 - 5e-25 88.6 0.9 1.5e-24 87.0 0.8 1.9 1 1 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Cytomega_UL20A PF05984.12 CBY19863.1 - 0.028 14.7 0.5 0.073 13.4 0.1 1.8 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein ETF PF01012.21 CBY19864.1 - 2.3e-46 157.9 0.8 3.2e-46 157.5 0.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TonB_2 PF13103.6 CBY19864.1 - 0.094 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 TonB C terminal UCR_hinge PF02320.16 CBY19865.1 - 9.5e-10 38.5 0.5 2.2e-09 37.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein SET PF00856.28 CBY19867.1 - 0.00068 20.1 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-C2H2_4 PF13894.6 CBY19867.1 - 0.0041 17.8 24.8 0.69 10.9 1.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY19867.1 - 0.096 13.2 21.2 0.31 11.6 2.0 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 CBY19867.1 - 0.45 10.8 7.5 0.79 10.1 6.7 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon SET PF00856.28 CBY19868.1 - 0.068 13.6 0.0 0.09 13.2 0.0 1.2 1 0 0 1 1 1 0 SET domain zf-B_box PF00643.24 CBY19868.1 - 0.15 12.2 2.0 0.48 10.6 1.3 1.9 2 0 0 2 2 2 0 B-box zinc finger Lipoprotein_10 PF03202.13 CBY19869.1 - 0.0059 17.0 1.4 0.0059 17.0 1.4 2.4 2 1 0 2 2 2 1 Putative mycoplasma lipoprotein, C-terminal region FNIP_N PF14636.6 CBY19869.1 - 0.51 11.3 0.1 0.51 11.3 0.1 2.7 3 1 0 3 3 3 0 Folliculin-interacting protein N-terminus LRR_4 PF12799.7 CBY19870.1 - 1.2e-11 44.7 14.7 6.3e-05 23.3 4.7 3.8 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY19870.1 - 6.6e-10 38.8 5.0 7.8e-10 38.5 2.6 2.3 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 CBY19870.1 - 3.9e-08 32.9 25.6 4.1e-05 23.3 8.8 3.2 1 1 2 3 3 3 3 Leucine rich repeat DUF2393 PF09624.10 CBY19870.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) LRR_1 PF00560.33 CBY19870.1 - 0.81 10.5 5.4 21 6.2 0.1 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CBY19870.1 - 2.3 8.5 10.0 52 4.3 0.9 4.4 4 0 0 4 4 4 0 Leucine Rich repeat DUF4407 PF14362.6 CBY19870.1 - 4.6 6.5 7.0 21 4.3 7.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF725 PF05267.12 CBY19870.1 - 5.7 6.9 6.7 0.5 10.4 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF725) Prp18 PF02840.15 CBY19870.1 - 6.4 6.8 8.6 0.43 10.6 0.5 2.7 2 1 2 4 4 4 0 Prp18 domain LemA PF04011.12 CBY19870.1 - 8.1 6.3 10.3 0.84 9.5 4.0 2.4 3 0 0 3 3 3 0 LemA family BLOC1_2 PF10046.9 CBY19870.1 - 8.3 6.8 14.9 0.32 11.3 3.6 3.7 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DSBA PF01323.20 CBY19876.1 - 9.6e-25 87.5 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain GCV_T PF01571.21 CBY19877.1 - 7.4e-11 41.9 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SoxG PF04268.12 CBY19877.1 - 0.02 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family RUN PF02759.19 CBY19878.1 - 6.5e-12 45.6 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 RUN domain LSM PF01423.22 CBY19879.1 - 1.8e-23 82.0 0.1 1.9e-23 81.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY19879.1 - 0.014 15.5 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 CBY19879.1 - 0.097 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Hfq protein VERL PF11386.8 CBY19879.1 - 0.11 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin ATP-synt_C PF00137.21 CBY19880.1 - 8.6e-33 112.5 35.4 2.9e-21 75.6 13.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PIRT PF15099.6 CBY19880.1 - 0.3 10.7 1.1 0.51 9.9 1.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family NADH5_C PF06455.11 CBY19880.1 - 3.8 7.1 12.2 0.055 13.1 5.2 1.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus BRE1 PF08647.11 CBY19881.1 - 0.008 16.2 11.1 0.008 16.2 11.1 8.0 4 2 4 8 8 8 3 BRE1 E3 ubiquitin ligase Trypsin PF00089.26 CBY19882.1 - 9e-29 100.9 0.0 1.3e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kazal_1 PF00050.21 CBY19883.1 - 3e-18 65.6 6.8 1.8e-12 47.1 2.7 2.2 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CBY19883.1 - 9.9e-12 44.8 11.7 7.4e-10 38.8 3.2 2.4 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain EMC3_TMCO1 PF01956.16 CBY19884.1 - 1.1e-47 161.9 1.5 1.8e-47 161.2 0.1 1.8 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like HSNSD PF12062.8 CBY19885.1 - 7.2e-100 335.0 4.7 1.1e-99 334.5 4.7 1.3 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 CBY19885.1 - 5.9e-24 85.0 0.0 1.6e-23 83.5 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY19885.1 - 1e-05 26.0 0.0 0.00066 20.1 0.0 2.6 1 1 1 2 2 2 1 Sulfotransferase family DnaJ PF00226.31 CBY19886.1 - 1.9e-18 66.3 0.6 3.6e-18 65.4 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CBY19886.1 - 0.039 14.0 2.8 0.064 13.3 2.8 1.3 1 0 0 1 1 1 0 Pam16 HlyIII PF03006.20 CBY19888.1 - 1.4e-60 204.8 24.4 1.7e-60 204.5 24.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.8 CBY19888.1 - 0.61 10.3 2.9 0.72 10.1 0.1 2.6 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 NPL4 PF05021.15 CBY19889.1 - 0.019 14.3 0.3 0.021 14.2 0.3 1.1 1 0 0 1 1 1 0 NPL4 family Homeodomain PF00046.29 CBY19890.1 - 4.3e-23 80.9 8.3 7.1e-23 80.2 8.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY19890.1 - 0.0043 16.9 0.5 0.0043 16.9 0.5 2.1 3 0 0 3 3 3 1 Homeobox KN domain GAIN_A PF18619.1 CBY19890.1 - 0.018 15.3 1.0 0.041 14.1 1.0 1.6 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Glyco_hydro_9 PF00759.19 CBY19891.1 - 7.1e-97 325.4 1.0 9e-74 249.3 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 9 Thyroglobulin_1 PF00086.18 CBY19891.1 - 3.1e-07 30.0 1.6 7.7e-07 28.7 1.6 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat NPC1_N PF16414.5 CBY19892.1 - 0.027 14.0 0.1 0.092 12.3 0.0 1.8 2 0 0 2 2 2 0 Niemann-Pick C1 N terminus Peptidase_S8 PF00082.22 CBY19893.1 - 1.4e-42 146.0 4.7 4.2e-40 137.9 4.7 2.2 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY19893.1 - 1.8e-15 56.7 0.0 1.4e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CBY19893.1 - 1.4e-12 48.2 0.9 2.9e-12 47.2 0.9 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Macin PF14865.6 CBY19893.1 - 1.5 9.4 9.3 0.37 11.4 4.0 2.6 2 1 1 3 3 3 0 Macin Geminin PF07412.12 CBY19894.1 - 1.5e-10 41.1 4.1 1.7e-10 41.0 4.1 1.1 1 0 0 1 1 1 1 Geminin HOOK PF05622.12 CBY19894.1 - 0.0005 18.4 3.9 0.00051 18.3 3.9 1.0 1 0 0 1 1 1 1 HOOK protein DivIVA PF05103.13 CBY19894.1 - 0.012 15.7 2.3 0.012 15.7 2.3 1.6 1 1 0 1 1 1 0 DivIVA protein DUF724 PF05266.14 CBY19894.1 - 0.021 14.7 2.4 0.024 14.5 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Sec34 PF04136.15 CBY19894.1 - 0.024 14.5 2.8 0.028 14.3 2.8 1.1 1 0 0 1 1 1 0 Sec34-like family Type2_restr_D3 PF16902.5 CBY19894.1 - 0.032 14.1 0.4 0.056 13.4 0.4 1.6 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain UPF0242 PF06785.11 CBY19894.1 - 0.035 14.2 5.9 0.038 14.1 5.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 CBY19894.1 - 0.04 13.6 7.1 0.049 13.4 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Fmp27_WPPW PF10359.9 CBY19894.1 - 0.051 12.4 2.2 0.049 12.5 2.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF5094 PF17015.5 CBY19894.1 - 0.077 13.1 6.2 0.081 13.0 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Cep57_CLD_2 PF14197.6 CBY19894.1 - 0.079 13.1 12.4 0.89 9.7 3.3 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 IclR PF01614.18 CBY19894.1 - 0.19 11.6 1.4 0.25 11.2 1.4 1.2 1 0 0 1 1 1 0 Bacterial transcriptional regulator Laminin_II PF06009.12 CBY19894.1 - 0.2 11.7 4.3 0.24 11.4 4.3 1.1 1 0 0 1 1 1 0 Laminin Domain II zf-C4H2 PF10146.9 CBY19894.1 - 0.24 11.7 3.7 0.27 11.5 3.7 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DivIC PF04977.15 CBY19894.1 - 0.8 9.5 7.1 0.37 10.6 1.0 2.1 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 CBY19894.1 - 0.93 9.6 11.3 0.82 9.8 2.7 2.4 1 1 1 2 2 2 0 bZIP transcription factor WD40 PF00400.32 CBY19895.1 - 1.2e-11 44.9 12.5 0.00065 20.5 0.1 5.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY19895.1 - 1.5e-08 34.8 1.0 0.00024 21.3 0.0 4.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2655 PF10848.8 CBY19895.1 - 0.019 15.3 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) Frtz PF11768.8 CBY19895.1 - 0.02 13.2 0.0 2.6 6.2 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz fn3 PF00041.21 CBY19896.1 - 5.2e-66 219.0 2.9 1.3e-13 51.0 0.1 6.2 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.16 CBY19896.1 - 3.5e-61 203.3 1.1 4e-16 58.9 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY19896.1 - 5.1e-36 123.1 10.6 3.8e-10 40.2 0.1 7.2 8 0 0 8 8 7 6 Immunoglobulin domain ig PF00047.25 CBY19896.1 - 9.5e-24 83.4 7.1 2.3e-05 24.5 0.0 6.5 6 0 0 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 CBY19896.1 - 9.1e-23 80.4 4.1 6.4e-06 26.4 0.0 6.7 7 0 0 7 7 7 5 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY19896.1 - 2.8e-17 63.1 4.2 0.00073 20.1 0.0 6.6 6 0 0 6 6 6 4 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 CBY19896.1 - 6e-09 36.1 3.1 0.16 12.2 0.0 5.1 5 2 0 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY19896.1 - 2.7e-08 33.8 0.2 0.4 10.8 0.0 4.6 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain PhoD_N PF16655.5 CBY19896.1 - 2.3e-07 31.2 0.1 0.31 11.6 0.0 5.5 5 0 0 5 5 5 2 PhoD-like phosphatase, N-terminal domain C1-set PF07654.15 CBY19896.1 - 0.036 14.4 0.7 5.1 7.6 0.0 3.8 4 0 0 4 4 3 0 Immunoglobulin C1-set domain DUF2369 PF10179.9 CBY19896.1 - 0.046 14.1 0.1 74 3.8 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) Izumo-Ig PF16706.5 CBY19896.1 - 0.063 13.3 0.2 31 4.7 0.0 3.7 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain PRIMA1 PF16101.5 CBY19896.1 - 1.7 8.7 5.5 4.8 7.2 5.5 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AAA PF00004.29 CBY19901.1 - 1.5e-85 284.3 0.0 1.9e-46 157.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY19901.1 - 3.5e-19 68.3 4.5 2.5e-09 36.8 0.3 3.2 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CBY19901.1 - 1.3e-11 45.2 5.4 4.5e-05 23.9 0.1 5.2 3 2 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 CBY19901.1 - 2e-11 43.9 0.0 2.2e-05 24.2 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CBY19901.1 - 2.1e-10 41.0 0.0 0.00011 22.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 CBY19901.1 - 1.2e-09 38.0 3.6 0.00032 20.6 0.1 3.9 4 0 0 4 4 4 2 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 CBY19901.1 - 1.6e-09 38.1 0.0 0.0037 17.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CBY19901.1 - 4.3e-09 36.5 0.0 0.00039 20.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CBY19901.1 - 4.7e-09 36.6 2.7 0.025 14.9 0.0 4.9 2 2 2 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 CBY19901.1 - 2.2e-07 30.9 0.0 0.023 14.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 CBY19901.1 - 2.8e-06 27.9 1.6 0.0061 17.1 0.0 3.3 3 1 0 3 3 2 2 AAA domain TsaE PF02367.17 CBY19901.1 - 2.9e-06 27.3 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CBY19901.1 - 3e-06 26.7 1.1 0.012 14.9 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.6 CBY19901.1 - 6e-06 26.0 3.6 0.59 9.7 0.1 4.7 3 1 1 4 4 4 1 AAA domain AAA_17 PF13207.6 CBY19901.1 - 8.8e-06 26.2 0.0 0.17 12.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CBY19901.1 - 1.4e-05 25.4 0.0 0.056 13.8 0.0 3.3 2 2 0 2 2 2 2 RNA helicase ATPase PF06745.13 CBY19901.1 - 1.7e-05 24.3 1.1 0.12 11.7 0.0 3.2 2 1 1 3 3 3 2 KaiC ABC_tran PF00005.27 CBY19901.1 - 3.3e-05 24.4 0.7 0.1 13.1 0.1 3.8 2 2 0 2 2 2 1 ABC transporter AAA_5 PF07728.14 CBY19901.1 - 3.8e-05 23.7 5.8 0.0024 17.9 0.1 4.7 4 2 0 4 4 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CBY19901.1 - 5.3e-05 23.0 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Rad17 PF03215.15 CBY19901.1 - 0.0001 22.3 0.3 0.0065 16.4 0.0 3.0 3 1 0 3 3 3 1 Rad17 P-loop domain AAA_28 PF13521.6 CBY19901.1 - 0.00013 22.3 2.8 0.018 15.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 CBY19901.1 - 0.00018 20.8 0.4 0.0095 15.2 0.0 2.6 3 0 0 3 3 3 1 TIP49 P-loop domain DUF2075 PF09848.9 CBY19901.1 - 0.00021 20.7 0.0 0.17 11.1 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CBY19901.1 - 0.00022 20.7 1.5 0.028 13.8 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBY19901.1 - 0.00031 20.6 0.0 0.43 10.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY19901.1 - 0.00083 19.1 0.0 0.16 11.7 0.0 3.6 4 1 0 4 4 4 1 Sigma-54 interaction domain NACHT PF05729.12 CBY19901.1 - 0.00086 19.3 3.9 0.1 12.5 0.0 3.7 4 1 0 4 4 3 1 NACHT domain AAA_24 PF13479.6 CBY19901.1 - 0.00094 18.9 0.1 2.4 7.8 0.0 3.3 4 0 0 4 4 2 2 AAA domain ATPase_2 PF01637.18 CBY19901.1 - 0.002 18.1 1.7 1.1 9.2 0.1 4.8 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CBY19901.1 - 0.0022 17.9 3.0 0.57 10.1 0.0 3.8 3 1 0 3 3 3 1 NTPase DUF815 PF05673.13 CBY19901.1 - 0.0034 16.6 0.0 0.44 9.7 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 CBY19901.1 - 0.0051 16.0 0.2 0.58 9.3 0.0 3.0 3 0 0 3 3 2 1 NB-ARC domain AAA_19 PF13245.6 CBY19901.1 - 0.0053 17.1 1.0 3.7 7.9 0.1 3.5 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 CBY19901.1 - 0.0061 16.7 0.0 0.034 14.3 0.0 2.3 2 1 0 2 2 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 CBY19901.1 - 0.0096 15.5 0.4 0.69 9.4 0.0 3.2 2 2 0 2 2 2 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 CBY19901.1 - 0.044 12.9 0.1 0.28 10.2 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CBY19901.1 - 0.073 12.8 0.4 5.4 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain VGLL4 PF15245.6 CBY19901.1 - 0.081 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 PduV-EutP PF10662.9 CBY19901.1 - 0.093 12.5 0.3 3.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation eIF3_p135 PF12807.7 CBY19901.1 - 0.1 12.6 0.1 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 AAA_29 PF13555.6 CBY19901.1 - 0.14 11.9 0.1 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain SKI PF01202.22 CBY19901.1 - 0.31 11.1 4.2 2.3 8.3 0.0 3.8 4 0 0 4 4 4 0 Shikimate kinase AAA_11 PF13086.6 CBY19901.1 - 1.2 8.9 5.4 2.9 7.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain Lipase PF00151.19 CBY19902.1 - 1.4e-41 143.0 0.0 8.3e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 Lipase DUF900 PF05990.12 CBY19902.1 - 8e-06 25.5 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 CBY19902.1 - 9.2e-05 23.1 0.0 0.00014 22.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 CBY19902.1 - 0.0043 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CBY19902.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.12 CBY19902.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DOMON PF03351.17 CBY19906.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 DOMON domain Carb_anhydrase PF00194.21 CBY19908.1 - 1.8e-67 227.6 5.2 2.2e-67 227.3 5.2 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1516 PF07457.11 CBY19909.1 - 0.06 13.5 0.8 0.13 12.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) DSPc PF00782.20 CBY19910.1 - 1.9e-35 121.6 0.0 2.7e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY19910.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBY19910.1 - 0.0032 17.1 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CBY19910.1 - 0.0042 17.4 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain Par3_HAL_N_term PF12053.8 CBY19910.1 - 0.042 14.1 0.0 5.6 7.3 0.0 2.3 1 1 1 2 2 2 0 N-terminal of Par3 and HAL proteins EF-hand_6 PF13405.6 CBY19912.1 - 2.5e-07 30.1 2.8 0.082 12.9 0.0 4.2 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY19912.1 - 1.1e-06 29.0 0.3 0.0066 16.9 0.0 2.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBY19912.1 - 3.2e-05 23.2 3.4 0.072 12.7 0.0 4.6 4 1 1 5 5 5 2 EF hand EF-hand_8 PF13833.6 CBY19912.1 - 0.0018 18.0 4.3 0.0068 16.2 0.1 3.2 2 1 1 3 3 3 1 EF-hand domain pair Kelch_1 PF01344.25 CBY19913.1 - 0.00014 21.4 1.0 1.1 8.8 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY19913.1 - 0.00045 20.2 1.0 0.91 9.6 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY19913.1 - 0.0066 16.7 5.3 8.7 6.8 0.0 4.6 4 1 1 5 5 5 2 Kelch motif Ephrin PF00812.17 CBY19914.1 - 9.6e-45 152.0 0.5 1.4e-44 151.5 0.5 1.2 1 0 0 1 1 1 1 Ephrin DUF2207 PF09972.9 CBY19914.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 CBY19914.1 - 0.5 10.3 1.9 0.95 9.4 1.9 1.4 1 0 0 1 1 1 0 Syndecan domain SpoIIIAH PF12685.7 CBY19915.1 - 0.061 13.1 0.4 0.058 13.2 0.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3519 PF12033.8 CBY19915.1 - 0.38 11.2 3.0 0.56 10.6 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3519) MGC-24 PF05283.11 CBY19915.1 - 2.4 8.6 7.3 4.3 7.8 7.3 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Orn_Arg_deC_N PF02784.16 CBY19916.1 - 6.6e-15 55.1 0.0 1.8e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Ion_trans_2 PF07885.16 CBY19917.1 - 7.3e-29 99.6 20.8 4.3e-15 55.4 4.5 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CBY19917.1 - 1.8e-06 27.4 10.9 7.9e-05 22.0 0.0 2.5 2 1 0 2 2 2 2 Ion transport protein VIT1 PF01988.19 CBY19917.1 - 0.023 14.6 5.0 0.84 9.5 4.9 2.4 1 1 0 1 1 1 0 VIT family IgaA PF07095.11 CBY19917.1 - 0.17 9.8 0.0 0.24 9.3 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF2070 PF09843.9 CBY19917.1 - 2 6.6 5.3 2.7 6.2 5.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) EGF_CA PF07645.15 CBY19918.1 - 1.4e-06 28.4 4.9 1.4e-06 28.4 4.9 3.0 2 1 0 2 2 2 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY19918.1 - 0.013 15.8 3.5 0.013 15.8 3.5 3.0 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site Glyco_hydro_38N PF01074.22 CBY19919.1 - 1.6e-78 264.0 8.5 2.3e-78 263.5 8.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CBY19919.1 - 1.2e-22 81.0 0.0 3e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CBY19919.1 - 1.8e-12 47.3 0.0 3.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Transketolase_C PF02780.20 CBY19920.1 - 1.1e-39 135.1 0.0 1.8e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 CBY19920.1 - 0.0058 16.3 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 CBY19920.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Glutaredoxin PF00462.24 CBY19921.1 - 1.8e-15 56.9 0.0 2.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Exo_endo_phos PF03372.23 CBY19922.1 - 7e-17 61.7 0.0 1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_lid_5 PF17865.1 CBY19923.1 - 0.003 17.6 0.1 0.0051 16.9 0.1 1.4 1 0 0 1 1 1 1 Midasin AAA lid domain DUF4405 PF14358.6 CBY19923.1 - 9.2 6.9 9.3 9.7 6.8 4.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) UNC-93 PF05978.16 CBY19924.1 - 2.5e-34 118.2 9.9 4.1e-34 117.6 9.9 1.3 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CBY19924.1 - 0.00022 20.2 11.4 0.00035 19.6 11.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily BppU_IgG PF18667.1 CBY19924.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain TMEM208_SND2 PF05620.11 CBY19924.1 - 0.32 10.8 0.0 0.32 10.8 0.0 2.5 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 GAGBD PF16828.5 CBY19925.1 - 0.0031 17.6 0.1 0.0059 16.7 0.1 1.5 1 0 0 1 1 1 1 GAG-binding domain on surface antigen GBP PF02263.19 CBY19925.1 - 0.019 14.3 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain VWA_3 PF13768.6 CBY19926.1 - 9e-12 45.2 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY19926.1 - 3.4e-08 34.1 0.0 9.6e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CBY19926.1 - 1.6e-07 31.7 0.0 3.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 CBY19926.1 - 6e-07 29.7 0.3 3.3e-06 27.3 0.1 2.3 2 1 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 CBY19926.1 - 0.0011 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein FERM_M PF00373.18 CBY19926.1 - 0.028 14.8 0.1 0.056 13.9 0.1 1.8 1 1 0 1 1 1 0 FERM central domain SH3_1 PF00018.28 CBY19927.1 - 7e-20 70.4 0.2 1.7e-10 40.3 0.1 2.2 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CBY19927.1 - 7.1e-20 70.6 0.2 1.3e-10 40.9 0.1 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CBY19927.1 - 1.3e-15 56.8 0.0 2.6e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 CBY19927.1 - 8.7e-07 29.1 0.4 0.0034 17.6 0.1 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain Mucin_bdg PF03272.13 CBY19927.1 - 0.1 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module HofP PF10748.9 CBY19927.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA utilization proteins HofP AAA-ATPase_like PF09820.9 CBY19928.1 - 0.094 12.1 0.0 0.099 12.0 0.0 1.0 1 0 0 1 1 1 0 Predicted AAA-ATPase RhoGEF PF00621.20 CBY19931.1 - 2.2e-23 83.4 1.1 4.7e-23 82.4 1.1 1.6 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 CBY19931.1 - 1.2e-06 28.5 6.3 2.2e-06 27.7 6.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Copper-fist PF00649.18 CBY19931.1 - 0.089 12.3 1.4 0.27 10.8 1.4 1.7 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-piccolo PF05715.13 CBY19931.1 - 3.2 8.0 5.6 0.83 9.8 2.0 1.8 2 0 0 2 2 2 0 Piccolo Zn-finger PHD_4 PF16866.5 CBY19931.1 - 4.3 7.5 5.9 15 5.7 5.2 2.1 1 1 1 2 2 2 0 PHD-finger Prok-RING_2 PF14445.6 CBY19931.1 - 7.8 6.7 7.5 3.2 8.0 4.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Zf_RING PF16744.5 CBY19931.1 - 9.1 6.5 7.1 37 4.5 7.1 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger Histone PF00125.24 CBY19935.1 - 5.1e-12 46.3 0.0 6.7e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CBY19935.1 - 6.1e-12 45.1 0.2 6.1e-12 45.1 0.2 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CBY19935.1 - 0.00029 21.0 0.0 0.00043 20.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Tetraspanin PF00335.20 CBY19936.1 - 7.7e-07 29.1 1.2 9.8e-07 28.7 1.2 1.2 1 0 0 1 1 1 1 Tetraspanin family NADPH_Ox PF08414.10 CBY19936.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 Respiratory burst NADPH oxidase zf-C4 PF00105.18 CBY19937.1 - 2.6e-20 72.7 12.1 5e-20 71.7 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY19937.1 - 5.7e-10 39.1 2.7 1.3e-09 38.0 2.7 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor AgrB PF04647.15 CBY19937.1 - 0.084 12.2 0.4 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 Accessory gene regulator B HLH PF00010.26 CBY19938.1 - 6.1e-13 48.5 0.4 3.2e-12 46.2 0.8 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain tRNA-synt_His PF13393.6 CBY19939.1 - 2e-35 122.6 0.0 2.9e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CBY19939.1 - 1e-11 44.8 0.0 2.5e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CBY19939.1 - 0.00044 19.9 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.20 CBY19939.1 - 0.029 13.8 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Aa_trans PF01490.18 CBY19940.1 - 3e-39 134.9 25.1 7.7e-39 133.6 25.1 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Monooxygenase_B PF04744.12 CBY19940.1 - 0.1 11.4 0.1 0.27 10.0 0.0 1.6 2 0 0 2 2 2 0 Monooxygenase subunit B protein O-FucT PF10250.9 CBY19942.1 - 0.011 15.5 0.1 0.022 14.5 0.1 1.6 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase TPR_1 PF00515.28 CBY19943.1 - 4.3e-11 42.1 4.8 0.00044 19.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY19943.1 - 9.4e-10 37.9 3.6 0.0014 18.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY19943.1 - 1.2e-06 28.7 0.0 0.08 13.2 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY19943.1 - 6.4e-06 26.0 5.4 0.00027 20.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY19943.1 - 4.6e-05 23.8 0.0 0.013 16.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 CBY19943.1 - 0.00017 22.1 0.3 0.0015 19.1 0.1 2.7 1 1 1 2 2 2 1 Sel1 repeat TPR_16 PF13432.6 CBY19943.1 - 0.0002 21.9 0.0 0.5 11.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY19943.1 - 0.0073 16.5 0.1 2.2 8.6 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBY19943.1 - 0.0094 16.3 0.0 0.55 10.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY19943.1 - 0.012 15.6 0.3 0.86 9.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3919 PF13057.6 CBY19943.1 - 0.014 15.0 0.7 0.026 14.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) MIT PF04212.18 CBY19943.1 - 0.016 15.2 1.6 3.8 7.7 0.4 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 CBY19943.1 - 0.024 15.1 0.0 3 8.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY19943.1 - 0.028 14.1 3.1 0.22 11.2 1.6 2.8 2 1 0 2 2 2 0 TPR repeat DUF4446 PF14584.6 CBY19943.1 - 0.049 13.6 0.4 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) GramPos_pilinBB PF16569.5 CBY19943.1 - 0.061 14.1 0.3 0.12 13.2 0.3 1.5 1 0 0 1 1 1 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain TPR_1 PF00515.28 CBY19944.1 - 0.015 15.1 0.9 0.015 15.1 0.9 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY19944.1 - 0.1 12.8 3.9 0.26 11.5 0.8 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat EGF PF00008.27 CBY19945.1 - 5.8e-61 202.3 266.3 3.4e-06 27.2 8.7 18.9 19 0 0 19 19 19 17 EGF-like domain hEGF PF12661.7 CBY19945.1 - 1.8e-48 161.6 239.7 1.5e-06 28.6 4.6 20.8 19 1 0 19 19 19 15 Human growth factor-like EGF EGF_2 PF07974.13 CBY19945.1 - 1.4e-16 60.5 312.1 0.019 15.3 8.0 19.3 19 0 0 19 19 19 17 EGF-like domain FXa_inhibition PF14670.6 CBY19945.1 - 3.9e-05 23.8 224.9 0.63 10.4 5.0 19.3 10 5 9 19 19 19 10 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CBY19945.1 - 0.0065 16.7 294.4 0.019 15.2 8.8 18.7 5 5 13 18 18 18 6 Calcium-binding EGF domain EGF_3 PF12947.7 CBY19945.1 - 0.064 13.5 0.6 0.064 13.5 0.6 19.9 12 6 6 18 18 18 0 EGF domain Beta-prism_lec PF16458.5 CBY19945.1 - 0.16 12.0 0.0 1.1 9.3 0.0 2.4 3 0 0 3 3 3 0 Beta-prism lectin Forkhead PF00250.18 CBY19946.1 - 1.2e-37 128.0 0.2 2.3e-37 127.1 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain Sod_Fe_N PF00081.22 CBY19947.1 - 1.1e-08 35.4 0.4 3.7e-08 33.7 0.0 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ADH_zinc_N PF00107.26 CBY19948.1 - 8.7e-11 41.9 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 CBY19948.1 - 0.02 14.4 0.1 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 CBY19948.1 - 0.026 14.2 0.6 0.051 13.3 0.6 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ABC_tran PF00005.27 CBY19949.1 - 5.4e-37 127.4 0.0 1e-36 126.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CBY19949.1 - 7.8e-28 97.9 1.9 1e-27 97.5 1.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CBY19949.1 - 3.9e-06 26.5 2.7 5.3e-05 22.7 0.1 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY19949.1 - 0.00081 19.8 0.0 0.0048 17.3 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 CBY19949.1 - 0.00091 18.6 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 CBY19949.1 - 0.0057 16.4 0.8 0.014 15.1 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 CBY19949.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 CBY19949.1 - 0.013 15.8 0.0 0.059 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBY19949.1 - 0.014 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBY19949.1 - 0.016 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBY19949.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CBY19949.1 - 0.068 12.2 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 CBY19949.1 - 0.12 13.0 0.0 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain INTS2 PF14750.6 CBY19950.1 - 9.4e-109 364.5 23.0 1.3e-108 364.0 23.0 1.1 1 0 0 1 1 1 1 Integrator complex subunit 2 TAP42 PF04177.12 CBY19952.1 - 6.4e-30 104.4 8.9 7.4e-30 104.2 8.9 1.1 1 0 0 1 1 1 1 TAP42-like family DUF5027 PF16430.5 CBY19953.1 - 0.09 12.6 0.4 0.12 12.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5027) Gln-synt_N PF03951.19 CBY19954.1 - 4.1e-13 48.9 0.0 5.5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Pyrid_oxidase_2 PF13883.6 CBY19955.1 - 9.4e-22 77.8 0.0 1e-21 77.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EF-hand_7 PF13499.6 CBY19956.1 - 3e-23 82.0 5.2 2.4e-16 59.9 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY19956.1 - 2.2e-22 76.9 6.8 2.6e-07 29.7 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY19956.1 - 1.1e-19 68.6 4.6 1.9e-05 24.2 0.2 3.8 4 0 0 4 4 3 3 EF-hand domain EF-hand_5 PF13202.6 CBY19956.1 - 1.4e-14 52.9 7.7 0.00046 19.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CBY19956.1 - 2.2e-13 49.8 9.3 0.00037 20.3 0.1 3.9 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CBY19956.1 - 3.4e-07 30.2 2.0 0.022 14.7 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY19956.1 - 0.0021 18.4 0.6 0.49 10.7 0.1 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1801 PF08818.11 CBY19956.1 - 0.039 14.5 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DU1801) EF-hand_9 PF14658.6 CBY19956.1 - 0.051 13.9 0.0 2.5 8.5 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain Caleosin PF05042.13 CBY19956.1 - 0.055 13.4 1.6 6.6 6.6 0.0 3.2 2 1 2 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 CBY19956.1 - 0.084 13.1 0.7 0.96 9.7 0.3 2.6 2 1 0 2 2 2 0 Dockerin type I domain zf-UBR PF02207.20 CBY19957.1 - 2.8e-06 27.4 18.2 6.9e-06 26.1 18.2 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) E3_UbLigase_R4 PF13764.6 CBY19958.1 - 5e-285 947.8 17.0 1.4e-267 890.1 3.0 3.2 2 1 1 4 4 4 2 E3 ubiquitin-protein ligase UBR4 PWI PF01480.17 CBY19958.1 - 3.2e-28 97.9 0.2 2.6e-26 91.7 0.0 3.2 2 0 0 2 2 2 1 PWI domain HTH_16 PF12645.7 CBY19958.1 - 0.036 14.1 0.1 0.98 9.5 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2884 PF11101.8 CBY19958.1 - 0.46 10.0 8.2 0.18 11.3 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) DZR PF12773.7 CBY19958.1 - 9.1 6.4 20.4 1.1 9.4 13.1 3.0 3 0 0 3 3 3 0 Double zinc ribbon LEM PF03020.15 CBY19959.1 - 3.7e-05 23.2 0.1 0.00013 21.4 0.1 2.1 1 0 0 1 1 1 1 LEM domain Ank_2 PF12796.7 CBY19959.1 - 0.00037 21.0 0.0 0.0016 19.0 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY19959.1 - 0.013 16.0 0.0 0.076 13.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 CBY19959.1 - 0.025 15.1 0.0 0.14 12.8 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat GST_C_3 PF14497.6 CBY19959.1 - 0.026 14.7 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ank_4 PF13637.6 CBY19959.1 - 0.027 15.1 0.0 0.072 13.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RNA_pol_Rpb8 PF03870.15 CBY19960.1 - 1.8e-48 164.3 0.0 2e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CBY19960.1 - 1.3e-05 25.2 0.0 0.0014 18.7 0.0 2.0 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G SCAB-Ig PF16709.5 CBY19960.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein DUF4094 PF13334.6 CBY19962.1 - 0.083 13.3 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CAP_N PF01213.19 CBY19965.1 - 0.058 12.9 0.0 0.063 12.8 0.0 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Kelch_1 PF01344.25 CBY19966.1 - 1.1e-16 60.1 3.1 1.7e-05 24.3 0.0 3.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CBY19966.1 - 1.1e-11 44.3 0.0 0.0088 16.0 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CBY19966.1 - 1.1e-11 44.5 0.2 0.00037 20.7 0.0 4.0 1 1 3 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CBY19966.1 - 2.1e-10 40.6 0.6 2.3e-05 24.5 0.0 3.7 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY19966.1 - 5.1e-10 39.1 0.0 0.011 15.7 0.0 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CBY19966.1 - 0.00082 19.3 3.9 2 8.5 0.1 3.7 2 1 1 3 3 3 2 Galactose oxidase, central domain Raf1_HTH PF18579.1 CBY19966.1 - 0.16 11.6 0.1 0.98 9.2 0.0 2.4 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain Med25_NR-box PF11244.8 CBY19967.1 - 0.16 12.4 0.2 19 5.7 0.1 2.3 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing DUF3350 PF11830.8 CBY19967.1 - 0.27 11.6 0.1 0.27 11.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) PMP22_Claudin PF00822.20 CBY19968.1 - 1.3e-07 31.6 1.6 1.7e-07 31.3 1.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY19968.1 - 0.049 13.4 0.8 0.068 12.9 0.8 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase_Tyr PF07714.17 CBY19972.1 - 1.9e-44 151.9 0.0 7.7e-42 143.4 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBY19972.1 - 1e-27 97.2 0.1 1.6e-25 90.0 0.0 3.0 2 1 0 3 3 3 1 Protein kinase domain Recep_L_domain PF01030.24 CBY19972.1 - 4.4e-08 33.2 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Receptor L domain GF_recep_IV PF14843.6 CBY19972.1 - 3.8e-07 30.0 24.0 2.8e-05 23.9 8.8 2.9 3 0 0 3 3 3 2 Growth factor receptor domain IV Furin-like PF00757.20 CBY19972.1 - 0.0093 15.8 12.0 0.0093 15.8 12.0 3.2 2 1 1 3 3 3 2 Furin-like cysteine rich region Kdo PF06293.14 CBY19972.1 - 0.023 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2040 PF09745.9 CBY19972.1 - 0.12 12.4 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) zf-RING_2 PF13639.6 CBY19974.1 - 4.6e-07 30.1 12.3 4.6e-07 30.1 12.3 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CBY19974.1 - 4.6e-05 23.3 12.3 4.6e-05 23.3 12.3 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY19974.1 - 0.00018 21.3 20.8 0.00024 20.9 13.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY19974.1 - 0.00049 19.9 11.8 0.00049 19.9 11.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY19974.1 - 0.00089 19.2 12.8 0.0036 17.3 6.0 3.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_4 PF14570.6 CBY19974.1 - 0.0092 15.8 10.4 0.0092 15.8 10.4 2.3 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 CBY19974.1 - 0.011 15.7 8.4 0.019 14.9 8.4 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 CBY19974.1 - 0.028 14.3 9.1 0.028 14.3 9.1 2.9 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 DUF2120 PF09893.9 CBY19974.1 - 0.067 13.3 0.3 0.094 12.8 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Rtf2 PF04641.12 CBY19974.1 - 0.087 12.2 6.4 0.13 11.6 6.3 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger DUF2202 PF09968.9 CBY19974.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) UPF0181 PF03701.14 CBY19974.1 - 0.19 11.4 0.1 3.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) DUF2256 PF10013.9 CBY19974.1 - 0.47 10.6 7.0 1.1 9.4 0.2 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_11 PF17123.5 CBY19974.1 - 0.72 9.6 9.5 0.42 10.4 5.6 2.6 2 0 0 2 2 2 0 RING-like zinc finger Sulfotransfer_1 PF00685.27 CBY19976.1 - 1.5e-07 31.2 0.3 2.1e-07 30.7 0.3 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY19976.1 - 0.01 16.2 0.1 0.078 13.3 0.1 2.2 1 1 0 1 1 1 0 Sulfotransferase family Thioredoxin_2 PF13098.6 CBY19977.1 - 0.054 14.0 0.4 0.084 13.3 0.4 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CBY19977.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin CYYR1 PF10873.8 CBY19978.1 - 2.3 8.7 7.6 0.89 10.0 1.5 2.1 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 TERB2 PF15101.6 CBY19980.1 - 5.4 7.0 8.0 0.8 9.7 3.1 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 MIF4G PF02854.19 CBY19982.1 - 1.1e-22 80.7 1.8 1.2e-18 67.5 0.2 2.2 2 0 0 2 2 2 2 MIF4G domain Pterin_bind PF00809.22 CBY19984.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.0 1 0 0 1 1 1 0 Pterin binding enzyme SSP160 PF06933.11 CBY19985.1 - 0.011 14.0 12.0 0.015 13.6 12.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.11 CBY19985.1 - 6.2 4.8 7.0 9.2 4.2 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA PF00004.29 CBY19986.1 - 1.5e-10 41.6 0.0 5.6e-10 39.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CBY19986.1 - 1.6e-05 24.8 0.1 4.3e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 CBY19986.1 - 2.8e-05 24.2 0.2 0.0001 22.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_8 PF12780.7 CBY19986.1 - 0.00026 20.4 1.2 0.042 13.2 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 CBY19986.1 - 0.00061 19.8 0.0 0.0038 17.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBY19986.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBY19986.1 - 0.002 18.3 0.1 0.012 15.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CBY19986.1 - 0.0026 18.3 0.5 0.015 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBY19986.1 - 0.0088 16.3 0.7 1.2 9.4 0.3 2.9 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 CBY19986.1 - 0.0098 15.8 1.4 0.056 13.4 0.0 2.8 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_25 PF13481.6 CBY19986.1 - 0.021 14.4 0.0 0.063 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 CBY19986.1 - 0.099 13.0 0.1 0.38 11.1 0.1 2.1 1 0 0 1 1 1 0 AAA C-terminal domain AAA_16 PF13191.6 CBY19986.1 - 0.19 12.1 0.3 7.9 6.8 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain Sec2p PF06428.11 CBY19987.1 - 0.028 14.4 1.3 0.68 9.9 1.5 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p TPR_19 PF14559.6 CBY19987.1 - 0.041 14.4 1.6 3.1 8.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AidB_N PF18158.1 CBY19988.1 - 3.6e-21 75.7 0.0 5.4e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY19988.1 - 0.00014 22.0 0.2 0.00022 21.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Guanylate_kin PF00625.21 CBY19989.1 - 3e-41 141.1 0.1 1.3e-40 139.0 0.0 1.8 2 0 0 2 2 2 1 Guanylate kinase SH3_1 PF00018.28 CBY19989.1 - 1.4e-08 34.2 0.2 4.2e-08 32.7 0.2 1.9 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY19989.1 - 7e-08 32.0 0.0 1.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CBY19989.1 - 0.0024 17.7 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF218 PF02698.17 CBY19990.1 - 1.9e-08 34.4 0.1 2.1e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 DUF218 domain DUF1870 PF08965.10 CBY19992.1 - 0.1 12.6 0.2 1.1 9.3 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1870) UCH PF00443.29 CBY19998.1 - 1e-15 57.9 0.0 1.1e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CBY19999.1 - 1.9e-15 57.1 0.1 2e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 CBY19999.1 - 1.9e-06 27.8 19.8 1.9e-06 27.8 19.8 2.1 2 0 0 2 2 2 1 MYND finger USP7_C2 PF14533.6 CBY19999.1 - 0.0016 18.2 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 CBY19999.1 - 0.013 15.1 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF424 PF04242.13 CBY19999.1 - 0.023 14.9 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF424) zf-CCCH_7 PF18586.1 CBY19999.1 - 1.1 9.7 6.3 13 6.2 2.0 3.6 2 2 1 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 BBS1 PF14779.6 CBY20000.1 - 1.5e-38 132.7 0.0 6.7e-37 127.3 0.0 2.4 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.6 CBY20000.1 - 1.5e-06 27.8 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 PTHB1 N-terminus BBS2_Mid PF14783.6 CBY20000.1 - 1.2e-05 25.3 0.3 0.00045 20.2 0.1 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region STAS PF01740.21 CBY20000.1 - 0.0045 16.6 0.1 0.024 14.3 0.1 2.2 2 0 0 2 2 2 1 STAS domain Cpn60_TCP1 PF00118.24 CBY20002.1 - 1.2e-86 291.3 14.6 2.3e-86 290.4 14.6 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DZF PF07528.14 CBY20003.1 - 4.6e-28 98.5 0.0 2.9e-27 95.9 0.0 2.3 2 0 0 2 2 2 1 DZF domain dsrm PF00035.26 CBY20003.1 - 7.8e-20 71.4 2.8 2.8e-06 27.9 0.1 3.9 3 0 0 3 3 3 3 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CBY20003.1 - 8e-07 29.1 3.1 0.007 16.5 0.1 4.1 3 1 0 3 3 3 3 Dicer dimerisation domain HDV_ag PF01517.18 CBY20003.1 - 0.15 11.9 2.3 1.3 8.8 0.2 2.3 1 1 0 2 2 2 0 Hepatitis delta virus delta antigen DuoxA PF10204.9 CBY20004.1 - 8.9e-68 228.3 7.7 1.3e-67 227.8 7.7 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor Ion_trans PF00520.31 CBY20005.1 - 3.6e-05 23.1 0.1 9.8e-05 21.7 0.1 1.6 2 0 0 2 2 2 1 Ion transport protein Phage_TTP_12 PF16461.5 CBY20006.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP Carb_anhydrase PF00194.21 CBY20007.1 - 4.6e-75 252.4 0.0 5.5e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Trypan_PARP PF05887.11 CBY20007.1 - 0.0088 16.0 9.8 0.018 15.0 9.8 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TSP_1 PF00090.19 CBY20009.1 - 0.00019 21.6 20.3 0.0018 18.5 11.0 11.2 13 0 0 13 13 13 2 Thrombospondin type 1 domain DUF5052 PF16475.5 CBY20009.1 - 0.075 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) Ribosomal_L7Ae PF01248.26 CBY20010.1 - 1.5e-25 88.7 0.1 1.8e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CBY20010.1 - 0.0026 17.8 0.1 0.0028 17.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 CBY20010.1 - 0.0056 16.5 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain MMS1_N PF10433.9 CBY20011.1 - 1.7e-89 300.7 5.0 1.7e-89 300.7 1.7 2.4 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CBY20011.1 - 2.8e-68 230.6 1.0 6.6e-65 219.5 0.1 3.3 3 0 0 3 3 3 2 CPSF A subunit region DUF1923 PF09083.10 CBY20011.1 - 0.037 13.7 0.1 12 5.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1923) eIF-5a PF01287.20 CBY20013.1 - 2.8e-17 62.6 2.7 4.4e-17 61.9 2.7 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CBY20013.1 - 0.00015 21.8 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain T4_deiodinase PF00837.17 CBY20015.1 - 1e-13 51.2 0.0 1.1e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase CH PF00307.31 CBY20016.1 - 1.1e-19 70.6 0.0 2.6e-16 59.8 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain Baculo_PEP_C PF04513.12 CBY20016.1 - 0.023 14.7 0.2 0.56 10.2 0.0 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_12 PF08242.12 CBY20016.1 - 0.099 13.4 0.3 0.67 10.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Goodbye PF17109.5 CBY20016.1 - 0.32 11.5 4.3 6.3 7.3 0.1 3.7 3 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Exonuc_VII_L PF02601.15 CBY20016.1 - 0.62 9.6 4.3 3.5 7.1 4.3 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 CBY20016.1 - 2.7 8.7 8.9 4.7 8.0 1.1 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) Neur_chan_LBD PF02931.23 CBY20019.1 - 3e-43 147.8 0.3 4e-43 147.4 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY20019.1 - 6.4e-30 105.0 10.9 6.3e-25 88.6 6.8 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Abhydrolase_1 PF00561.20 CBY20020.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Kelch_2 PF07646.15 CBY20021.1 - 0.018 15.0 0.1 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.6 CBY20021.1 - 0.34 11.0 1.9 0.44 10.6 0.1 1.9 2 0 0 2 2 2 0 Kelch motif GATA PF00320.27 CBY20022.1 - 1.1e-30 105.0 19.0 7.4e-16 57.5 5.7 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CBY20022.1 - 2.4e-05 23.7 8.7 0.025 14.1 0.7 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 CBY20022.1 - 0.013 15.6 4.1 8 6.7 0.2 3.6 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) OrfB_Zn_ribbon PF07282.11 CBY20022.1 - 0.096 12.6 7.7 2.6 8.1 0.7 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 CBY20022.1 - 0.11 12.7 5.7 1.4 9.1 0.4 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 CBY20022.1 - 0.12 12.5 3.0 8.4 6.6 0.2 2.6 2 1 0 2 2 2 0 Zinc ribbon domain TDP43_N PF18694.1 CBY20022.1 - 0.23 11.3 0.3 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DZR PF12773.7 CBY20022.1 - 0.32 11.1 8.0 7.9 6.6 0.5 2.7 1 1 2 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 CBY20022.1 - 0.4 10.6 5.8 3.6 7.5 1.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ArfGap PF01412.18 CBY20022.1 - 0.68 10.0 11.9 0.17 11.9 0.6 3.2 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Prim_Zn_Ribbon PF08273.12 CBY20022.1 - 2.5 8.4 11.3 0.46 10.8 2.3 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Cytochrom_c3_2 PF14537.6 CBY20022.1 - 3.9 8.0 6.7 1.7 9.2 1.4 2.1 1 1 1 2 2 2 0 Cytochrome c3 Acyl-CoA_dh_M PF02770.19 CBY20023.1 - 4.7e-26 90.8 0.0 8.4e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CBY20023.1 - 1.5e-22 80.4 0.6 2.2e-17 63.6 0.1 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY20023.1 - 1.2e-18 67.8 0.0 2.9e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain GATA PF00320.27 CBY20024.1 - 2.1e-31 107.2 19.0 3.3e-16 58.6 5.7 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CBY20024.1 - 4.3e-06 26.1 8.7 0.011 15.2 0.7 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 CBY20024.1 - 0.0017 18.4 4.2 3.3 7.9 0.2 3.2 1 1 2 3 3 3 2 Probable metal-binding protein (DUF2387) OrfB_Zn_ribbon PF07282.11 CBY20024.1 - 0.016 15.1 7.4 0.85 9.6 0.5 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain ArfGap PF01412.18 CBY20024.1 - 0.016 15.3 8.0 0.039 14.0 0.6 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.17 CBY20024.1 - 0.023 14.6 4.1 1.7 8.5 1.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 CBY20024.1 - 0.023 14.8 5.7 0.67 10.2 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 CBY20024.1 - 0.041 14.0 3.9 3.7 7.7 0.2 2.7 2 1 1 3 3 3 0 Zinc ribbon domain TDP43_N PF18694.1 CBY20024.1 - 0.058 13.3 0.3 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DZR PF12773.7 CBY20024.1 - 0.13 12.3 9.2 8.3 6.5 2.2 2.9 1 1 1 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 CBY20024.1 - 0.55 9.7 8.0 0.27 10.7 0.3 3.2 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cytochrome_C554 PF13435.6 CBY20024.1 - 0.63 11.0 4.3 7.1 7.6 1.9 2.7 2 1 0 2 2 2 0 Cytochrome c554 and c-prime Prim_Zn_Ribbon PF08273.12 CBY20024.1 - 0.87 9.9 12.4 0.19 12.0 2.3 2.9 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase Cytochrom_c3_2 PF14537.6 CBY20024.1 - 1.3 9.5 7.0 0.62 10.6 1.2 2.2 1 1 1 2 2 2 0 Cytochrome c3 zinc_ribbon_15 PF17032.5 CBY20024.1 - 2 9.2 5.5 13 6.6 1.9 2.8 1 1 2 3 3 3 0 zinc-ribbon family Rubredoxin_2 PF18073.1 CBY20024.1 - 2.8 7.7 12.1 15 5.4 0.1 4.2 4 0 0 4 4 4 0 Rubredoxin metal binding domain Elf1 PF05129.13 CBY20024.1 - 3.3 7.8 9.7 4.6 7.4 0.4 2.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 CBY20024.1 - 5.5 6.5 12.8 4.4 6.9 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain ASD2 PF08687.11 CBY20025.1 - 0.58 9.7 2.4 0.87 9.1 2.4 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Acyl-CoA_dh_1 PF00441.24 CBY20026.1 - 4.1e-39 134.2 0.7 6e-39 133.6 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY20026.1 - 4.1e-26 91.0 0.0 7.3e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY20026.1 - 1.2e-18 67.9 0.0 2.5e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY20026.1 - 0.00025 21.3 0.0 0.00043 20.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3671 PF12420.8 CBY20027.1 - 0.037 14.1 3.6 0.045 13.8 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function Sre PF03125.18 CBY20027.1 - 0.041 13.0 6.6 0.046 12.9 6.6 1.0 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor PMP22_Claudin PF00822.20 CBY20027.1 - 0.056 13.3 2.9 0.067 13.1 2.9 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Rab5ip PF07019.12 CBY20027.1 - 1.8 9.2 7.4 7.1 7.3 7.4 1.8 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Phospholip_A2_1 PF00068.19 CBY20028.1 - 4.9e-09 36.6 2.8 4.9e-09 36.6 2.8 2.4 2 0 0 2 2 2 1 Phospholipase A2 PDZ PF00595.24 CBY20029.1 - 8.6e-20 70.9 1.7 7.9e-14 51.8 0.3 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY20029.1 - 5.5e-08 32.5 0.3 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY20029.1 - 0.036 14.4 0.2 5.6 7.4 0.1 2.4 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.24 CBY20030.1 - 9.7e-17 61.1 0.1 1.6e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 PDZ domain EGF_3 PF12947.7 CBY20030.1 - 1.9e-11 43.9 55.1 1.4e-05 25.1 8.4 4.8 4 0 0 4 4 4 3 EGF domain PDZ_6 PF17820.1 CBY20030.1 - 2e-07 30.7 0.0 4.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain hEGF PF12661.7 CBY20030.1 - 4.6e-05 23.9 29.3 0.071 13.8 3.2 5.8 5 0 0 5 5 5 4 Human growth factor-like EGF PDZ_2 PF13180.6 CBY20030.1 - 0.004 17.5 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain cEGF PF12662.7 CBY20030.1 - 0.006 16.5 2.5 0.006 16.5 2.5 5.1 5 1 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.27 CBY20030.1 - 0.0097 16.2 2.9 0.0097 16.2 2.9 5.4 4 1 0 4 4 4 2 EGF-like domain EGF_CA PF07645.15 CBY20030.1 - 0.26 11.5 49.0 0.043 14.0 2.9 5.2 3 1 1 4 4 4 0 Calcium-binding EGF domain LRR_8 PF13855.6 CBY20031.1 - 1.7e-06 27.7 19.0 0.00016 21.4 3.7 4.0 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CBY20031.1 - 0.00024 21.4 18.0 0.034 14.6 3.9 4.8 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY20031.1 - 0.17 11.4 4.0 1.2 8.7 0.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 CBY20031.1 - 0.49 10.6 12.8 12 6.2 0.5 4.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBY20031.1 - 2.1 9.2 17.2 17 6.4 1.0 5.8 5 1 1 6 6 6 0 Leucine Rich Repeat ABC1 PF03109.16 CBY20032.1 - 1.2e-31 109.4 0.0 2.4e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family ANAPC4_WD40 PF12894.7 CBY20033.1 - 2.7e-05 24.4 0.4 1.1 9.6 0.1 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY20033.1 - 0.03 13.7 2.0 0.051 12.9 0.4 1.9 1 1 0 1 1 1 0 WD40-like domain PQQ_2 PF13360.6 CBY20033.1 - 0.068 12.7 0.0 0.48 10.0 0.0 2.0 1 1 1 2 2 2 0 PQQ-like domain Hira PF07569.11 CBY20033.1 - 0.071 12.8 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split Dcc1 PF09724.9 CBY20034.1 - 2.8e-56 191.2 1.0 3.5e-56 190.9 1.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 SMC_ScpB PF04079.16 CBY20034.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB TIL PF01826.17 CBY20035.1 - 2.8e-30 104.3 98.4 3.8e-11 43.1 17.8 6.5 5 1 0 5 5 5 4 Trypsin Inhibitor like cysteine rich domain cEGF PF12662.7 CBY20035.1 - 1.1 9.3 21.9 11 6.0 0.2 6.0 5 0 0 5 5 5 0 Complement Clr-like EGF-like CBP_BcsN PF17038.5 CBY20037.1 - 0.053 12.9 0.1 1.8 7.9 0.1 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsN Exo_endo_phos PF03372.23 CBY20038.1 - 2.1e-12 47.0 0.0 6.4e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_15 PF09445.10 CBY20039.1 - 7.9e-41 139.4 0.0 1.4e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 CBY20039.1 - 1.2e-08 35.0 0.1 5.5e-07 29.5 0.0 2.4 1 1 1 2 2 2 1 Met-10+ like-protein Methyltransf_31 PF13847.6 CBY20039.1 - 1.4e-06 28.2 0.0 2.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY20039.1 - 3.6e-06 27.6 0.0 8.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CBY20039.1 - 1.1e-05 25.3 0.1 7.7e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 CBY20039.1 - 0.0002 21.1 0.0 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 CBY20039.1 - 0.00037 21.1 0.0 0.001 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBY20039.1 - 0.0008 19.4 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 CBY20039.1 - 0.0011 18.2 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.14 CBY20039.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 CBY20039.1 - 0.018 14.4 0.0 0.045 13.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 CBY20039.1 - 0.046 12.9 0.0 0.086 12.0 0.0 1.5 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase UDPG_MGDP_dh_N PF03721.14 CBY20039.1 - 0.056 13.0 1.1 0.28 10.7 0.1 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.26 CBY20039.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Cupin_8 PF13621.6 CBY20039.1 - 0.076 12.7 1.8 2.1 8.0 1.5 2.2 2 0 0 2 2 2 0 Cupin-like domain 5_nucleotid PF05761.14 CBY20040.1 - 8e-127 423.9 0.5 9.2e-127 423.7 0.5 1.0 1 0 0 1 1 1 1 5' nucleotidase family YdjC PF04794.12 CBY20041.1 - 2e-18 67.3 0.0 2.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 YdjC-like protein B56 PF01603.20 CBY20042.1 - 7.6e-103 344.7 4.2 9.9e-103 344.3 4.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CBY20042.1 - 0.053 13.4 2.3 1.7 8.6 0.0 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Telomere_reg-2 PF10193.9 CBY20042.1 - 0.12 12.8 0.0 6.1 7.3 0.0 3.2 4 0 0 4 4 4 0 Telomere length regulation protein IRF-2BP1_2 PF11261.8 CBY20043.1 - 2.3e-14 52.7 1.0 6.4e-14 51.3 0.4 2.2 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4_2 PF13923.6 CBY20043.1 - 0.086 12.7 6.5 0.25 11.2 6.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CBY20044.1 - 5.4e-10 38.9 0.0 1.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY20044.1 - 0.032 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 CBY20044.1 - 0.093 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RR_TM4-6 PF06459.12 CBY20044.1 - 1.2 8.9 12.1 2.4 7.9 12.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Na_sulph_symp PF00939.19 CBY20045.1 - 6.3e-82 276.1 22.4 3.3e-81 273.7 15.3 2.1 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY20045.1 - 4.5e-28 98.3 31.9 6.1e-12 45.3 6.5 3.2 2 1 0 3 3 3 3 Citrate transporter DUF2407_C PF13373.6 CBY20045.1 - 0.12 12.6 0.1 0.36 11.0 0.1 1.8 1 0 0 1 1 1 0 DUF2407 C-terminal domain Pkinase PF00069.25 CBY20046.1 - 2.6e-68 230.3 0.0 3.2e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20046.1 - 8.1e-34 117.1 0.0 1.1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY20046.1 - 1.4e-05 24.6 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY20046.1 - 8.8e-05 21.6 0.0 0.0035 16.3 0.0 2.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY20046.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY20046.1 - 0.0017 17.8 0.2 0.0055 16.1 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4990 PF16380.5 CBY20046.1 - 0.077 13.1 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function Seadorna_VP7 PF07387.11 CBY20046.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 TSP9 PF11493.8 CBY20047.1 - 7.9 7.2 9.1 1.8 9.3 0.1 3.2 1 1 3 4 4 4 0 Thylakoid soluble phosphoprotein TSP9 EF-hand_1 PF00036.32 CBY20048.1 - 7.1e-20 69.0 8.6 1.2e-05 24.5 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY20048.1 - 1e-19 68.7 7.9 8.1e-05 22.3 1.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBY20048.1 - 3.6e-17 62.6 8.8 2.8e-09 37.3 3.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY20048.1 - 6.1e-13 47.6 6.4 0.0028 17.1 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY20048.1 - 2.3e-12 46.5 9.3 8.4e-10 38.4 1.7 3.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CBY20048.1 - 0.019 14.9 3.7 0.14 12.1 0.1 2.5 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Prok_Ub PF14454.6 CBY20048.1 - 0.036 13.7 0.1 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic Ubiquitin EF-hand_9 PF14658.6 CBY20048.1 - 1.5 9.2 5.1 6.5 7.2 0.3 3.3 2 2 0 2 2 2 0 EF-hand domain NAD_binding_3 PF03447.16 CBY20050.1 - 1.3e-06 29.1 0.0 1.8e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF108 PF01958.18 CBY20052.1 - 1.2e-08 35.2 0.0 1.8e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF108 Evf PF18270.1 CBY20052.1 - 0.04 13.3 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Virulence factor Evf IIGP PF05049.13 CBY20054.1 - 9.8e-35 120.3 0.0 1.5e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 CBY20054.1 - 2.5e-05 24.3 0.0 0.00011 22.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 CBY20054.1 - 0.00054 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 CBY20054.1 - 0.0026 17.3 0.2 0.51 9.8 0.1 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CBY20054.1 - 0.0032 18.0 0.9 0.0072 16.9 0.1 1.9 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 CBY20054.1 - 0.0084 16.0 0.1 0.036 14.0 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CBY20054.1 - 0.0098 16.2 2.1 0.036 14.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain FeoB_N PF02421.18 CBY20054.1 - 0.041 13.4 0.0 0.13 11.7 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CBY20054.1 - 0.053 13.2 0.3 0.099 12.4 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY20054.1 - 0.068 13.7 0.0 0.28 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CBY20054.1 - 0.087 13.0 0.3 0.66 10.2 0.3 2.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CBY20054.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Nucleoporin_FG PF13634.6 CBY20057.1 - 0.042 14.7 1.2 0.078 13.8 1.2 1.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region VCBS PF13517.6 CBY20059.1 - 1.7e-12 47.7 9.0 0.00082 19.9 0.2 4.3 4 1 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBY20059.1 - 0.013 15.6 10.3 2.6 8.2 0.1 4.8 5 0 0 5 5 5 0 FG-GAP repeat TPR_8 PF13181.6 CBY20060.1 - 5.2e-13 48.1 0.6 0.025 14.8 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY20060.1 - 7.6e-10 38.1 3.6 2 8.7 0.0 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY20060.1 - 5.1e-09 35.6 0.8 1.6 8.7 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY20060.1 - 3.2e-08 33.4 2.4 0.34 11.4 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY20060.1 - 1.3e-07 31.8 6.0 0.86 10.6 0.0 6.8 8 1 1 9 9 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 CBY20060.1 - 1.5e-06 28.4 1.7 3.8 8.4 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY20060.1 - 3.5e-06 26.6 2.2 0.044 13.5 0.0 5.3 6 0 0 6 6 6 1 TPR repeat TPR_16 PF13432.6 CBY20060.1 - 6.6e-06 26.7 1.0 4.1 8.1 0.0 6.0 6 1 1 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY20060.1 - 1.4e-05 25.2 9.7 0.005 17.0 0.3 4.4 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY20060.1 - 5.1e-05 23.7 5.0 0.94 10.0 0.1 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY20060.1 - 0.00026 21.0 1.0 0.012 15.7 0.0 3.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CBY20060.1 - 0.002 18.4 7.1 19 5.6 0.1 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY20060.1 - 0.0021 17.9 1.0 26 4.9 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY20060.1 - 0.0038 16.6 0.6 1.4 8.2 0.1 3.7 3 1 1 4 4 4 1 MalT-like TPR region TPR_9 PF13371.6 CBY20060.1 - 0.0074 16.4 6.9 1.3 9.2 0.0 4.8 6 1 0 6 6 5 2 Tetratricopeptide repeat BCNT PF07572.12 CBY20061.1 - 1.1e-17 63.9 9.9 2.6e-17 62.7 9.9 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development zf-C2HC_2 PF13913.6 CBY20062.1 - 2.8e-12 46.2 12.5 6.5e-09 35.5 0.2 3.0 3 0 0 3 3 3 2 zinc-finger of a C2HC-type YacG PF03884.14 CBY20062.1 - 0.00042 20.0 1.2 0.00042 20.0 1.2 2.6 3 0 0 3 3 3 1 DNA gyrase inhibitor YacG RNF220 PF15926.5 CBY20062.1 - 0.05 13.2 3.0 0.24 11.0 0.3 2.4 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Rad50_zn_hook PF04423.14 CBY20062.1 - 0.079 12.8 1.7 0.34 10.8 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.7 CBY20062.1 - 1.9 8.6 11.7 0.29 11.2 1.5 2.8 3 0 0 3 3 3 0 Double zinc ribbon Phosphodiest PF01663.22 CBY20063.1 - 2.7e-11 43.7 1.8 9.3e-10 38.6 0.5 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CBY20063.1 - 9e-06 25.3 0.1 4.3e-05 23.1 0.0 2.0 1 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 CBY20063.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Metalloenzyme superfamily ANAPC4_WD40 PF12894.7 CBY20064.1 - 1e-05 25.7 0.0 0.06 13.7 0.0 3.9 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IceA2 PF05862.11 CBY20064.1 - 0.098 12.6 0.1 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein WD40 PF00400.32 CBY20065.1 - 3e-16 59.5 0.1 0.00013 22.7 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20065.1 - 4.1e-11 43.0 0.0 0.021 15.1 0.0 4.7 3 3 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY20065.1 - 0.0039 17.1 0.0 0.5 10.2 0.0 2.8 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CBY20065.1 - 0.03 12.9 0.0 0.13 10.7 0.0 2.0 2 1 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 CBY20065.1 - 0.14 12.1 0.7 49 4.0 0.0 3.6 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CBY20065.1 - 0.18 10.8 0.5 15 4.4 0.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SNF2_N PF00176.23 CBY20066.1 - 2e-33 115.6 0.4 4e-33 114.6 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY20066.1 - 1.6e-13 50.9 1.0 3.8e-13 49.8 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY20066.1 - 1e-09 38.7 4.6 6e-08 32.9 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY20066.1 - 9.7e-07 28.2 0.0 2.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 CBY20066.1 - 1.9e-05 24.5 0.2 7.6e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 CBY20066.1 - 0.0042 17.1 0.1 0.026 14.5 0.1 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_25 PF13481.6 CBY20066.1 - 0.011 15.4 0.1 0.054 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF5339 PF17274.2 CBY20066.1 - 0.31 11.9 2.6 0.77 10.7 2.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5339) DAP PF15228.6 CBY20067.1 - 0.053 14.7 2.8 0.1 13.8 2.8 1.5 1 0 0 1 1 1 0 Death-associated protein Zn_ribbon_17 PF17120.5 CBY20068.1 - 8.4e-07 28.5 15.9 2e-06 27.3 15.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 CBY20068.1 - 0.002 18.4 0.2 0.0079 16.5 0.2 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY20068.1 - 0.0043 17.9 2.1 0.025 15.4 0.4 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat TMIE PF16038.5 CBY20069.1 - 6.6e-22 77.2 1.3 8.5e-22 76.8 1.3 1.2 1 0 0 1 1 1 1 TMIE protein LapA_dom PF06305.11 CBY20069.1 - 0.14 12.0 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain WD40 PF00400.32 CBY20070.1 - 1.4e-08 35.2 16.0 0.056 14.3 0.5 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20070.1 - 1.1e-05 25.7 0.2 0.26 11.6 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LRR_8 PF13855.6 CBY20071.1 - 3.2e-47 158.1 60.3 1.1e-09 37.9 2.9 9.8 3 2 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 CBY20071.1 - 3.5e-40 135.3 63.8 7e-07 29.5 0.8 12.2 7 2 7 14 14 14 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY20071.1 - 1.2e-10 41.2 31.9 0.00042 19.9 0.6 6.2 1 1 6 7 7 7 5 Leucine-rich repeat LRR_1 PF00560.33 CBY20071.1 - 1.9e-07 30.7 58.3 3.6 8.5 0.2 15.5 17 1 0 17 17 17 5 Leucine Rich Repeat LRR_5 PF13306.6 CBY20071.1 - 0.0018 18.2 13.3 0.0091 16.0 4.5 4.0 2 1 2 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 CBY20071.1 - 0.0041 17.1 54.1 0.7 10.1 0.4 12.9 15 0 0 15 15 15 5 Leucine Rich repeat CSTF_C PF14304.6 CBY20071.1 - 0.011 15.3 1.7 16 5.2 0.1 4.4 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal HA2 PF04408.23 CBY20072.1 - 1.8e-19 70.0 0.0 1.8e-19 70.0 0.0 3.8 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY20072.1 - 5.1e-14 52.6 0.0 1.2e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBY20072.1 - 2.5e-13 50.2 0.0 6e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBY20072.1 - 1.4e-07 31.4 0.1 4.2e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY20072.1 - 3.3e-05 24.2 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CBY20072.1 - 0.00029 20.8 0.0 0.00067 19.7 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 CBY20072.1 - 0.0038 17.0 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBY20072.1 - 0.0043 16.4 0.1 0.01 15.2 0.1 1.6 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.27 CBY20072.1 - 0.0068 16.9 0.0 0.025 15.1 0.0 2.0 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 CBY20072.1 - 0.0071 15.4 0.1 0.056 12.5 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 CBY20072.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CBY20072.1 - 0.028 14.1 0.1 0.061 12.9 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Microtub_bd PF16796.5 CBY20072.1 - 0.049 13.6 0.3 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Microtubule binding PhoH PF02562.16 CBY20072.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein UPF0730 PF15827.5 CBY20072.1 - 0.23 11.2 0.3 0.47 10.2 0.3 1.4 1 0 0 1 1 1 0 UPF0730 unknown protein family Ribophorin_II PF05817.14 CBY20074.1 - 2.4e-98 330.3 1.1 2.9e-98 330.1 1.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Desulfoferrodox PF01880.18 CBY20074.1 - 0.0031 18.1 0.0 4.5 7.9 0.0 2.7 2 0 0 2 2 2 2 Desulfoferrodoxin Lectin_C PF00059.21 CBY20075.1 - 7.3e-10 39.6 0.5 1.1e-09 38.9 0.5 1.3 1 1 0 1 1 1 1 Lectin C-type domain Phospholip_A2_1 PF00068.19 CBY20076.1 - 2.9e-20 72.8 9.8 4.7e-20 72.1 9.8 1.3 1 0 0 1 1 1 1 Phospholipase A2 Peptidase_M1_N PF17900.1 CBY20077.1 - 1.7e-24 87.0 0.1 5.3e-24 85.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CBY20077.1 - 2.2e-10 40.6 0.1 5.3e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain FAM176 PF14851.6 CBY20078.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.3 1 1 1 2 2 2 0 FAM176 family NOA36 PF06524.12 CBY20078.1 - 2.2 7.5 30.8 2.9 7.1 30.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 CBY20078.1 - 7.5 4.6 30.3 8.1 4.5 30.3 1.0 1 0 0 1 1 1 0 Nop14-like family Tube PF17212.3 CBY20079.1 - 0.022 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Tail tubular protein HTH_9 PF08221.11 CBY20079.1 - 0.15 12.2 0.0 0.69 10.1 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF1115 PF06544.12 CBY20080.1 - 4.7 7.3 12.5 0.48 10.5 7.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1115) FGF PF00167.18 CBY20081.1 - 2.1e-27 95.7 0.0 2.9e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 CBY20081.1 - 0.035 14.3 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Fascin domain CDtoxinA PF03498.14 CBY20081.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Glyco_transf_7N PF13733.6 CBY20082.1 - 4.4e-33 113.8 0.5 7.8e-33 113.0 0.5 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY20082.1 - 1.3e-21 76.0 0.4 4.8e-21 74.2 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase PLAC8 PF04749.17 CBY20083.1 - 1.5e-06 29.1 10.8 2e-06 28.7 10.8 1.2 1 0 0 1 1 1 1 PLAC8 family PspA_IM30 PF04012.12 CBY20084.1 - 0.0051 16.4 20.6 0.0098 15.5 20.6 1.4 1 0 0 1 1 1 1 PspA/IM30 family DUF5446 PF17522.2 CBY20084.1 - 0.061 13.5 2.0 0.21 11.8 2.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF1664 PF07889.12 CBY20084.1 - 0.88 9.6 4.5 2.4 8.2 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 CBY20084.1 - 2.6 7.3 14.1 0.67 9.3 9.8 2.0 2 0 0 2 2 2 0 FAM76 protein RVT_1 PF00078.27 CBY20085.1 - 2.7e-27 95.7 0.0 6.2e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DsrH PF04077.12 CBY20086.1 - 0.069 13.3 0.2 0.53 10.4 0.1 2.2 2 0 0 2 2 2 0 DsrH like protein Caveolin PF01146.17 CBY20088.1 - 1e-22 80.5 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 CBY20090.1 - 2.1e-46 157.2 1.6 2.7e-46 156.8 1.6 1.1 1 0 0 1 1 1 1 Caveolin Pox_I6 PF04595.13 CBY20091.1 - 0.061 12.3 5.1 0.1 11.6 0.9 2.0 1 1 1 2 2 2 0 Poxvirus I6-like family Vps23_core PF09454.10 CBY20091.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Vps23 core domain Dehydrin PF00257.19 CBY20091.1 - 1.6 9.3 3.8 2.2 8.8 3.8 1.2 1 0 0 1 1 1 0 Dehydrin WD40 PF00400.32 CBY20093.1 - 0.17 12.8 4.7 0.23 12.4 0.3 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat PAN_1 PF00024.26 CBY20094.1 - 0.00038 20.4 0.1 0.00038 20.4 0.1 2.7 3 0 0 3 3 3 1 PAN domain Phospholip_A2_1 PF00068.19 CBY20095.1 - 1.4e-06 28.8 1.4 1.9e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Phospholipase A2 APH PF01636.23 CBY20098.1 - 1.4e-05 25.2 0.1 1.9e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY20098.1 - 0.0002 20.8 0.6 0.00029 20.2 0.6 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 CBY20098.1 - 0.00059 19.5 0.9 0.00083 19.0 0.9 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Filament PF00038.21 CBY20099.1 - 0.00021 21.0 11.9 0.0028 17.3 3.7 2.2 2 0 0 2 2 2 2 Intermediate filament protein Golgin_A5 PF09787.9 CBY20099.1 - 0.0025 17.3 15.1 0.0032 17.0 7.4 2.3 2 0 0 2 2 2 1 Golgin subfamily A member 5 ICL PF00463.21 CBY20099.1 - 0.063 11.8 0.1 0.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Isocitrate lyase family Spc7 PF08317.11 CBY20099.1 - 0.083 11.8 15.8 0.11 11.3 3.0 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 CBY20099.1 - 0.16 12.9 20.4 9 7.3 0.1 4.0 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 CBY20099.1 - 0.35 11.0 8.7 0.27 11.4 0.4 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.6 CBY20099.1 - 0.4 11.2 11.2 0.13 12.7 0.4 2.5 2 0 0 2 2 2 0 AAA domain PKcGMP_CC PF16808.5 CBY20099.1 - 1.1 9.2 9.3 2.8 7.9 0.7 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase KIAA1430 PF13879.6 CBY20099.1 - 1.4 9.7 12.7 2.6 8.9 1.0 3.1 3 0 0 3 3 2 0 KIAA1430 homologue DUF724 PF05266.14 CBY20099.1 - 3.4 7.5 14.8 4.6 7.0 6.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 CBY20099.1 - 4.7 7.8 26.1 2.6 8.6 18.7 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 CBY20099.1 - 5.7 7.0 13.8 11 6.0 1.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Enkurin PF13864.6 CBY20099.1 - 5.8 7.4 16.7 6.4 7.3 3.4 3.3 3 0 0 3 3 3 0 Calmodulin-binding TPR_MLP1_2 PF07926.12 CBY20099.1 - 8 6.5 27.9 0.28 11.3 7.1 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein zf-3CxxC_2 PF17180.4 CBY20101.1 - 6.1e-18 65.3 11.4 6.1e-18 65.3 11.4 3.6 2 2 1 3 3 3 2 Zinc-binding domain DOT1 PF08123.13 CBY20103.1 - 4.5e-54 183.1 1.4 7.7e-54 182.3 1.4 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 CBY20103.1 - 0.0041 16.6 0.1 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase SH3_13 PF18335.1 CBY20103.1 - 0.14 12.0 0.0 0.57 10.1 0.0 2.0 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain zf-C2H2 PF00096.26 CBY20105.1 - 0.00017 21.8 20.7 0.13 12.8 1.6 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY20105.1 - 0.0058 16.9 14.9 1.6 9.1 0.2 4.7 4 1 0 4 4 4 2 C2H2 type zinc-finger (2 copies) Porphyrn_cat_1 PF18206.1 CBY20105.1 - 0.016 15.8 0.6 0.11 13.1 0.2 2.3 2 0 0 2 2 2 0 Porphyranase catalytic subdomain 1 zf-C2H2_4 PF13894.6 CBY20105.1 - 0.042 14.7 35.1 0.22 12.5 1.4 5.5 6 1 0 6 6 6 0 C2H2-type zinc finger ATPase-cat_bd PF12156.8 CBY20105.1 - 0.052 14.3 9.1 16 6.3 0.1 3.9 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase DUF2256 PF10013.9 CBY20105.1 - 0.054 13.6 9.4 5.5 7.2 0.0 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_9 PF14369.6 CBY20105.1 - 0.88 9.9 13.3 3.7 7.9 0.2 4.5 4 0 0 4 4 4 0 zinc-ribbon TFIIA PF03153.13 CBY20106.1 - 0.0091 16.0 8.1 0.012 15.7 8.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit IFP_35_N PF07334.13 CBY20106.1 - 0.015 15.4 3.4 0.037 14.1 3.4 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ATG16 PF08614.11 CBY20106.1 - 0.025 14.8 2.3 0.042 14.1 2.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF29 PF01724.16 CBY20106.1 - 0.039 14.2 0.3 0.059 13.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF29 CRA PF06589.11 CBY20106.1 - 0.046 13.8 2.6 0.067 13.3 2.6 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DivIC PF04977.15 CBY20106.1 - 0.43 10.4 3.1 0.76 9.6 3.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Abhydrolase_1 PF00561.20 CBY20107.1 - 1.9e-06 27.7 0.0 3.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY20107.1 - 0.00014 22.6 0.0 0.00023 21.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBY20107.1 - 0.00079 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF818 PF05677.12 CBY20107.1 - 0.0021 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) N6-adenineMlase PF10237.9 CBY20108.1 - 2e-13 50.4 0.0 2.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase zf-CCHC PF00098.23 CBY20108.1 - 0.0036 17.3 0.9 0.0036 17.3 0.9 3.7 4 0 0 4 4 4 1 Zinc knuckle CLIP1_ZNF PF16641.5 CBY20108.1 - 0.017 15.0 0.3 0.017 15.0 0.3 2.6 2 0 0 2 2 2 0 CLIP1 zinc knuckle zf-ribbon_3 PF13248.6 CBY20108.1 - 0.02 14.3 1.5 0.02 14.3 1.5 3.9 3 1 1 4 4 4 0 zinc-ribbon domain dsrm PF00035.26 CBY20109.1 - 6.5e-15 55.6 1.4 1.8e-05 25.4 0.0 3.8 3 1 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.7 CBY20109.1 - 0.00033 20.8 0.3 3.1 8.1 0.0 3.4 3 0 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 Syja_N PF02383.18 CBY20109.1 - 0.042 13.2 0.0 0.081 12.2 0.0 1.5 2 0 0 2 2 2 0 SacI homology domain DegT_DnrJ_EryC1 PF01041.17 CBY20109.1 - 0.16 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Histone_H2A_C PF16211.5 CBY20110.1 - 4.4e-20 71.1 1.6 4.4e-20 71.1 1.6 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CBY20110.1 - 2.1e-16 60.5 0.0 2.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY20110.1 - 0.0001 22.5 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY20111.1 - 3.5e-17 63.0 0.6 4.7e-17 62.6 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY20111.1 - 3.9e-07 30.3 0.0 8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBY20111.1 - 0.063 13.7 0.2 0.14 12.6 0.0 1.6 1 1 1 2 2 2 0 CENP-S protein DUF1018 PF06252.12 CBY20111.1 - 0.076 14.0 0.3 0.1 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DUF1248 PF06852.12 CBY20111.1 - 0.093 12.2 0.0 0.099 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) cNMP_binding PF00027.29 CBY20112.1 - 1.1e-20 73.5 0.1 1.6e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HupH_C PF04809.13 CBY20113.1 - 0.29 10.8 1.7 6.4 6.5 0.1 2.7 2 0 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region RHH_1 PF01402.21 CBY20113.1 - 0.76 9.8 4.6 1.3 9.0 0.5 3.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family PSK_trans_fac PF07704.11 CBY20113.1 - 1.2 10.0 5.7 1.2 9.9 0.5 3.5 3 0 0 3 3 3 0 Rv0623-like transcription factor DFP PF04127.15 CBY20114.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein cNMP_binding PF00027.29 CBY20115.1 - 3.6e-16 59.0 0.1 6.7e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RIIa PF02197.17 CBY20115.1 - 4.9e-08 32.5 0.0 9.6e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 CBY20115.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Dpy-30 motif Presenilin PF01080.17 CBY20117.1 - 4.9e-131 437.2 30.6 4.8e-89 298.9 19.8 2.7 3 0 0 3 3 3 2 Presenilin Gemini_mov PF01708.16 CBY20117.1 - 0.23 11.2 8.1 0.46 10.3 0.1 3.8 4 0 0 4 4 4 0 Geminivirus putative movement protein zf-RING_2 PF13639.6 CBY20120.1 - 1.1 9.7 22.1 0.19 12.1 12.3 3.2 2 1 1 3 3 3 0 Ring finger domain DUF5319 PF17252.2 CBY20120.1 - 4.7 7.5 8.2 0.87 9.8 1.1 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5319) zf-HC5HC2H PF13771.6 CBY20121.1 - 6e-14 52.1 4.2 5.7e-13 48.9 0.9 2.8 2 1 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBY20121.1 - 1.6e-08 34.7 6.6 3.3e-08 33.7 2.6 2.6 2 1 0 2 2 2 1 PHD-zinc-finger like domain Diacid_rec PF05651.13 CBY20121.1 - 0.2 11.3 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative sugar diacid recognition BCDHK_Adom3 PF10436.9 CBY20122.1 - 9.8e-41 139.3 0.3 1.5e-40 138.7 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBY20122.1 - 5.6e-09 36.5 0.0 1.2e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acyl-CoA_dh_N PF02771.16 CBY20124.1 - 1.3e-28 99.9 0.0 2.4e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 CBY20124.1 - 1e-26 94.0 0.5 1.6e-26 93.3 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY20124.1 - 1.5e-20 73.2 0.0 2.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY20124.1 - 5.4e-06 26.7 0.2 1.2e-05 25.6 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RRM_1 PF00076.22 CBY20125.1 - 1.7e-14 53.4 0.0 3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY20125.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 CBY20126.1 - 6.7e-46 156.8 0.3 8.9e-46 156.4 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20126.1 - 1.3e-16 60.7 1.1 1.6e-16 60.4 0.2 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBY20126.1 - 0.00074 18.6 0.3 0.0012 18.0 0.3 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase ADH_N PF08240.12 CBY20127.1 - 1.9e-22 79.2 4.4 6.6e-22 77.5 4.4 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBY20127.1 - 1.4e-21 76.8 0.2 2.6e-21 76.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CBY20127.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CBY20127.1 - 0.12 11.9 0.4 0.2 11.2 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Med9 PF07544.13 CBY20129.1 - 0.057 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 BUD22 PF09073.10 CBY20129.1 - 3 7.1 9.7 4.6 6.5 9.7 1.2 1 0 0 1 1 1 0 BUD22 U3_snoRNA_assoc PF08297.11 CBY20130.1 - 0.05 14.3 0.6 0.17 12.6 0.0 2.2 2 1 1 3 3 3 0 U3 snoRNA associated Pkinase PF00069.25 CBY20131.1 - 1.7e-35 122.7 0.0 3.4e-35 121.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20131.1 - 1.3e-12 47.6 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY20131.1 - 1.8e-06 28.0 0.0 4.7e-06 26.7 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY20131.1 - 3.7e-06 26.4 0.0 5.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY20131.1 - 0.00013 20.9 0.0 0.00018 20.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY20131.1 - 0.0015 17.9 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 CBY20131.1 - 0.026 14.1 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 CBY20131.1 - 0.029 14.0 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TetR_C_29 PF17938.1 CBY20131.1 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Choline_kinase PF01633.20 CBY20131.1 - 0.09 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ArfGap PF01412.18 CBY20132.1 - 5.5e-39 132.9 0.0 1e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ras PF00071.22 CBY20132.1 - 6.7e-18 64.8 0.0 1.5e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Ras family PH PF00169.29 CBY20132.1 - 8.2e-14 52.0 1.4 1e-13 51.7 0.4 1.8 2 0 0 2 2 1 1 PH domain Ank_2 PF12796.7 CBY20132.1 - 2.3e-07 31.3 0.1 4.3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY20132.1 - 4.5e-06 27.1 0.1 0.001 19.6 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY20132.1 - 3.3e-05 24.1 0.0 0.00012 22.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PH_2 PF08458.10 CBY20132.1 - 0.00024 21.4 0.0 0.00047 20.5 0.0 1.5 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_11 PF15413.6 CBY20132.1 - 0.0003 21.2 0.4 0.0008 19.8 0.4 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 CBY20132.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Roc PF08477.13 CBY20132.1 - 0.027 14.7 0.0 0.26 11.5 0.0 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank PF00023.30 CBY20132.1 - 0.037 14.5 0.4 0.13 12.8 0.1 2.1 2 0 0 2 2 1 0 Ankyrin repeat Ank_3 PF13606.6 CBY20132.1 - 0.093 13.3 0.3 0.46 11.2 0.1 2.3 2 0 0 2 2 2 0 Ankyrin repeat Fascin PF06268.13 CBY20132.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Fascin domain JHY PF15261.6 CBY20133.1 - 6.3e-21 75.5 6.4 6.3e-21 75.5 6.4 3.7 3 1 1 4 4 4 1 Jhy protein FRB_dom PF08771.11 CBY20133.1 - 0.059 13.8 1.1 0.3 11.5 0.2 2.7 2 1 1 3 3 3 0 FKBP12-rapamycin binding domain BIR PF00653.21 CBY20134.1 - 2.5e-07 31.2 6.6 0.0038 17.9 1.9 3.1 2 2 0 2 2 2 2 Inhibitor of Apoptosis domain PyrI_C PF02748.15 CBY20134.1 - 0.0093 15.9 3.1 0.17 11.8 0.4 3.1 3 0 0 3 3 3 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.26 CBY20135.1 - 0.00016 21.9 2.5 0.00034 20.9 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY20135.1 - 0.00022 21.8 2.2 0.00052 20.6 2.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 CBY20135.1 - 0.0047 17.3 0.6 0.014 15.8 0.6 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY20135.1 - 0.08 13.3 1.8 0.16 12.3 1.8 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY20135.1 - 0.15 12.6 2.3 9.1 6.9 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 CBY20135.1 - 0.15 11.8 0.8 0.28 11.0 0.8 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type Pkinase PF00069.25 CBY20137.1 - 2e-64 217.5 0.0 2e-64 217.5 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain PKK PF12474.8 CBY20137.1 - 1.2e-49 168.0 80.3 1.9e-30 105.8 35.0 5.5 4 1 2 6 6 6 2 Polo kinase kinase Pkinase_Tyr PF07714.17 CBY20137.1 - 1.3e-44 152.5 0.0 5.1e-44 150.5 0.0 2.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY20137.1 - 0.15 11.9 0.0 7.8 6.3 0.0 2.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family CagY_M PF07337.11 CBY20137.1 - 0.28 10.8 3.8 0.18 11.5 0.2 2.6 2 0 0 2 2 2 0 DC-EC Repeat LAGLIDADG_2 PF03161.13 CBY20137.1 - 1.1 9.2 12.0 0.18 11.8 2.9 2.6 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family Histone PF00125.24 CBY20138.1 - 2.2e-33 115.4 1.4 2.7e-33 115.1 1.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY20138.1 - 0.00052 20.3 0.2 0.0011 19.2 0.2 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBY20138.1 - 0.00065 20.0 0.1 0.00097 19.5 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBY20138.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold HMG_box PF00505.19 CBY20139.1 - 1.4e-19 70.3 3.1 1.7e-19 70.0 3.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY20139.1 - 1.2e-13 51.4 4.6 1.5e-13 51.1 4.6 1.1 1 0 0 1 1 1 1 HMG-box domain Homeodomain PF00046.29 CBY20140.1 - 2.3e-23 81.8 4.5 3.9e-23 81.1 4.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY20140.1 - 0.0076 16.1 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Tropomyosin PF00261.20 CBY20142.1 - 3e-81 272.3 85.9 1.4e-80 270.1 63.6 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 CBY20142.1 - 6.6e-26 91.2 76.4 1.7e-23 83.3 42.0 3.1 1 1 1 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 CBY20142.1 - 4.1e-07 30.1 37.7 0.00084 19.4 6.6 3.3 1 1 2 3 3 3 3 Laminin Domain II CLZ PF16526.5 CBY20142.1 - 4.3e-05 23.8 49.7 0.044 14.1 10.3 5.4 1 1 4 5 5 5 4 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 CBY20142.1 - 0.00012 22.1 72.7 0.0023 18.0 21.4 3.1 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein XhlA PF10779.9 CBY20142.1 - 0.0022 18.1 4.2 0.0022 18.1 4.2 6.4 2 1 4 6 6 6 3 Haemolysin XhlA SH3BP5 PF05276.14 CBY20142.1 - 0.0034 17.2 48.5 0.21 11.4 18.9 3.3 1 1 2 3 3 3 3 SH3 domain-binding protein 5 (SH3BP5) DUF1664 PF07889.12 CBY20142.1 - 0.0051 16.8 33.3 0.026 14.5 2.3 4.0 1 1 2 4 4 4 3 Protein of unknown function (DUF1664) Spectrin PF00435.21 CBY20142.1 - 0.02 15.4 16.3 0.02 15.4 16.3 4.1 1 1 3 4 4 3 0 Spectrin repeat ATG16 PF08614.11 CBY20142.1 - 0.021 15.0 58.5 0.026 14.7 20.2 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 CBY20142.1 - 0.022 14.3 44.1 0.65 9.5 23.3 2.6 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Prefoldin_2 PF01920.20 CBY20142.1 - 0.023 14.6 57.8 0.31 11.0 4.8 4.8 2 2 2 4 4 4 0 Prefoldin subunit Uds1 PF15456.6 CBY20142.1 - 0.56 10.4 47.6 7.6 6.7 8.9 3.8 1 1 2 3 3 3 0 Up-regulated During Septation Flagellin_N PF00669.20 CBY20142.1 - 1.1 9.4 24.0 2.1 8.5 0.1 4.1 1 1 4 5 5 5 0 Bacterial flagellin N-terminal helical region Spc7 PF08317.11 CBY20142.1 - 1.2 8.0 65.5 1.7 7.4 20.1 2.6 1 1 0 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 CBY20142.1 - 1.3 8.4 53.5 6.8 6.1 25.7 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF16 PF01519.16 CBY20142.1 - 1.3 9.5 40.6 0.41 11.2 2.3 4.3 1 1 3 4 4 4 0 Protein of unknown function DUF16 T3SSipB PF16535.5 CBY20142.1 - 1.4 9.4 55.1 8 6.9 6.3 4.5 1 1 4 5 5 5 0 Type III cell invasion protein SipB IFT57 PF10498.9 CBY20142.1 - 1.8 7.4 45.7 3.5 6.5 17.7 2.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TMPIT PF07851.13 CBY20142.1 - 2.1 7.5 42.2 0.38 10.0 7.5 3.1 1 1 2 3 3 3 0 TMPIT-like protein Nup54 PF13874.6 CBY20142.1 - 2.3 8.3 36.4 1.4 9.0 9.7 3.4 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 HrpB7 PF09486.10 CBY20142.1 - 2.5 8.5 51.2 2.4 8.5 3.1 4.8 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) Exonuc_VII_L PF02601.15 CBY20142.1 - 2.5 7.6 36.7 1.8e+04 -7.1 35.0 2.6 1 1 0 1 1 0 0 Exonuclease VII, large subunit KELK PF15796.5 CBY20142.1 - 2.8 8.5 58.3 2.6 8.6 6.8 4.7 1 1 3 5 5 5 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-F_leu_zip PF10473.9 CBY20142.1 - 3.6 7.6 65.1 0.031 14.3 28.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KxDL PF10241.9 CBY20142.1 - 5.1 7.4 29.0 0.05 13.9 8.8 3.9 2 1 3 5 5 4 0 Uncharacterized conserved protein DUF3584 PF12128.8 CBY20142.1 - 5.2 4.4 59.2 2.2 5.7 26.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 CBY20142.1 - 6 7.3 53.5 7.1 7.0 26.3 2.6 1 1 1 2 2 2 0 Fez1 BORCS7 PF16088.5 CBY20142.1 - 7.6 6.9 22.6 0.34 11.2 1.0 4.2 3 2 0 3 3 3 0 BLOC-1-related complex sub-unit 7 Sec34 PF04136.15 CBY20142.1 - 8.9 6.2 28.3 0.97 9.3 3.0 3.7 1 1 1 3 3 3 0 Sec34-like family ERM PF00769.19 CBY20142.1 - 9.4 6.0 77.3 2.2 8.0 33.6 3.0 1 1 2 3 3 3 0 Ezrin/radixin/moesin family WXG100 PF06013.12 CBY20142.1 - 9.8 6.5 26.0 2.9 8.2 3.4 4.9 3 2 2 5 5 5 0 Proteins of 100 residues with WXG Lipase PF00151.19 CBY20143.1 - 6e-50 170.4 0.0 1.6e-49 169.1 0.0 1.7 1 1 0 1 1 1 1 Lipase DUF900 PF05990.12 CBY20143.1 - 0.0027 17.2 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 CBY20143.1 - 0.08 13.5 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hist_deacetyl PF00850.19 CBY20144.1 - 4.7e-21 75.6 0.1 1.7e-19 70.5 0.0 2.7 2 1 1 3 3 3 1 Histone deacetylase domain LRR_11 PF18831.1 CBY20144.1 - 0.075 12.6 0.3 0.18 11.4 0.3 1.6 1 0 0 1 1 1 0 Leucine-rich repeat Runt PF00853.19 CBY20145.1 - 1.3e-61 205.9 0.0 2.2e-61 205.1 0.0 1.3 1 0 0 1 1 1 1 Runt domain BK_channel_a PF03493.18 CBY20146.1 - 3.4e-19 68.9 0.0 8.1e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CBY20146.1 - 1.1e-12 47.8 2.6 1.1e-12 47.8 2.6 2.4 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 CBY20146.1 - 0.00057 19.7 3.5 0.001 18.9 1.3 2.3 2 0 0 2 2 2 1 Ligand-gated ion channel Castor_Poll_mid PF06241.12 CBY20146.1 - 0.12 12.4 0.0 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Castor and Pollux, part of voltage-gated ion channel US6 PF17616.2 CBY20146.1 - 0.13 12.2 1.1 21 5.1 0.0 3.2 4 0 0 4 4 4 0 Viral unique short region 6 PH_8 PF15409.6 CBY20147.1 - 0.065 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 CBY20147.1 - 0.13 12.8 0.5 0.48 11.0 0.2 2.1 2 1 0 2 2 2 0 PH domain EF-hand_7 PF13499.6 CBY20149.1 - 1.8e-06 28.3 0.5 3.4e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY20149.1 - 0.00039 20.2 1.9 0.0004 20.2 0.1 2.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY20149.1 - 0.13 11.9 0.5 0.44 10.2 0.5 2.0 1 0 0 1 1 1 0 EF hand Phospholip_A2_1 PF00068.19 CBY20150.1 - 4.5e-06 27.1 0.3 6.4e-06 26.6 0.3 1.3 1 0 0 1 1 1 1 Phospholipase A2 LIM PF00412.22 CBY20152.1 - 3.2e-20 72.1 26.9 2.4e-10 40.5 9.6 2.4 2 0 0 2 2 2 2 LIM domain PDZ PF00595.24 CBY20152.1 - 1.1e-09 38.4 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY20152.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY20152.1 - 0.0039 17.5 0.0 0.0072 16.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain adh_short PF00106.25 CBY20153.1 - 1.2e-37 129.3 2.1 2.1e-37 128.5 2.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY20153.1 - 8.6e-32 110.6 2.4 4.7e-31 108.1 2.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY20153.1 - 5.8e-16 58.9 0.9 8.5e-16 58.4 0.9 1.2 1 0 0 1 1 1 1 KR domain Helicase_C_2 PF13307.6 CBY20154.1 - 9.8e-50 169.1 0.0 5.2e-49 166.7 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBY20154.1 - 8e-37 126.5 4.7 8e-37 126.5 4.7 2.0 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 CBY20154.1 - 3.9e-08 33.5 0.1 4.6e-07 30.0 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBY20154.1 - 1.7e-06 27.9 0.2 0.00049 19.9 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY20154.1 - 0.0087 16.3 1.4 1.4 9.2 0.7 3.2 2 1 0 2 2 2 1 AAA domain HBB PF06777.11 CBY20154.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Helical and beta-bridge domain PhoH PF02562.16 CBY20154.1 - 0.075 12.5 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Ras PF00071.22 CBY20157.1 - 8.4e-20 71.0 0.0 7.2e-19 68.0 0.0 2.2 1 1 0 1 1 1 1 Ras family BTB PF00651.31 CBY20157.1 - 5.1e-11 42.8 0.0 2.1e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Roc PF08477.13 CBY20157.1 - 4.2e-08 33.4 0.0 1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBY20158.1 - 3.7e-56 190.1 0.9 4.8e-56 189.7 0.9 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CBY20158.1 - 2.8e-05 23.7 2.4 0.00029 20.3 1.3 2.5 1 1 1 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 CBY20158.1 - 0.00096 18.6 0.0 0.0038 16.7 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 CBY20158.1 - 0.015 15.4 0.5 0.046 13.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain HAT_KAT11 PF08214.11 CBY20158.1 - 0.025 13.9 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Histone acetylation protein RsgA_GTPase PF03193.16 CBY20158.1 - 0.069 13.0 0.1 4.1 7.3 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase CCDC92 PF14916.6 CBY20158.1 - 0.087 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function FDX-ACB PF03147.14 CBY20158.1 - 0.11 12.9 0.4 0.25 11.8 0.1 1.8 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain MOZART2 PF12926.7 CBY20159.1 - 3.2e-06 26.7 0.0 5.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SapB_2 PF03489.17 CBY20159.1 - 0.023 14.8 0.1 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 Saposin-like type B, region 2 zf-C3HC4_2 PF13923.6 CBY20160.1 - 3.8e-12 45.8 10.3 8.4e-12 44.7 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LON_substr_bdg PF02190.16 CBY20160.1 - 2e-10 40.9 0.0 3.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4 PF00097.25 CBY20160.1 - 3.5e-09 36.4 7.9 1.1e-08 34.9 7.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY20160.1 - 4e-09 36.2 3.3 8.2e-09 35.2 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY20160.1 - 1e-08 35.0 9.1 4.3e-08 33.0 9.1 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY20160.1 - 1.1e-07 32.0 9.6 1.1e-07 32.0 9.6 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBY20160.1 - 3.3e-07 30.1 6.3 9.5e-07 28.6 6.3 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY20160.1 - 6.5e-06 26.0 6.5 1.6e-05 24.7 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBY20160.1 - 0.00074 19.6 9.7 0.0023 18.1 9.7 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 CBY20160.1 - 0.004 17.3 3.8 0.0085 16.2 3.8 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CBY20160.1 - 0.028 14.2 8.0 0.16 11.8 8.3 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CBY20160.1 - 0.05 13.9 11.3 0.23 11.8 11.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 CBY20160.1 - 0.26 11.2 8.1 0.92 9.4 7.7 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 CBY20160.1 - 0.49 10.5 5.9 0.85 9.8 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) SH2 PF00017.24 CBY20161.1 - 0.00021 21.3 0.0 0.0021 18.1 0.0 2.6 2 0 0 2 2 2 1 SH2 domain Cyt-b5 PF00173.28 CBY20162.1 - 7.9e-21 74.0 0.0 9.3e-21 73.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 CBY20164.1 - 4.6e-34 118.0 0.0 6.9e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20164.1 - 1.5e-07 30.9 0.0 2.4e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY20164.1 - 2.9e-07 30.1 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY20164.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF5589 PF17672.1 CBY20165.1 - 0.014 15.3 1.0 0.02 14.8 1.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5589) RSN1_TM PF13967.6 CBY20165.1 - 0.058 13.1 0.1 0.073 12.8 0.1 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport TROVE PF05731.11 CBY20166.1 - 2.1e-66 224.8 2.4 4.6e-39 134.7 0.0 2.1 1 1 1 2 2 2 2 TROVE domain Ig_3 PF13927.6 CBY20167.1 - 4.5e-19 68.8 5.8 9.8e-05 22.9 0.0 8.9 8 0 0 8 8 8 4 Immunoglobulin domain C2-set_2 PF08205.12 CBY20167.1 - 4.2e-17 62.0 5.9 0.0001 22.3 0.0 7.6 7 1 0 7 7 7 5 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 CBY20167.1 - 2.1e-15 56.8 3.0 0.042 14.2 0.0 8.0 8 1 1 9 9 9 3 Immunoglobulin domain I-set PF07679.16 CBY20167.1 - 2e-09 37.4 7.2 0.0018 18.3 0.1 7.1 7 2 0 7 7 7 2 Immunoglobulin I-set domain V-set PF07686.17 CBY20167.1 - 0.0018 18.4 0.1 0.36 11.0 0.2 3.6 3 0 0 3 3 3 1 Immunoglobulin V-set domain fn3 PF00041.21 CBY20167.1 - 0.0032 17.8 0.2 0.01 16.2 0.2 1.9 1 0 0 1 1 1 1 Fibronectin type III domain C2-set PF05790.15 CBY20167.1 - 0.035 14.3 3.9 24 5.2 0.0 5.1 5 0 0 5 5 5 0 Immunoglobulin C2-set domain ICAM_N PF03921.14 CBY20167.1 - 0.052 13.2 1.3 15 5.3 0.0 3.9 3 1 0 3 3 3 0 Intercellular adhesion molecule (ICAM), N-terminal domain FGFR3_TM PF18123.1 CBY20167.1 - 3.4 7.3 5.0 6.5 6.4 5.0 1.5 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain Pyridoxal_deC PF00282.19 CBY20168.1 - 1.3e-93 313.7 0.0 1.6e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 CBY20168.1 - 0.0046 16.3 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase MAM PF00629.23 CBY20169.1 - 7.2e-15 55.3 0.0 1.1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu T6SS_HCP PF05638.12 CBY20169.1 - 0.32 11.4 1.3 0.72 10.3 0.0 2.1 3 0 0 3 3 3 0 Type VI secretion system effector, Hcp Forkhead PF00250.18 CBY20170.1 - 7.2e-36 122.3 1.0 2.6e-19 69.3 0.0 3.8 3 0 0 3 3 3 3 Forkhead domain Cadherin PF00028.17 CBY20171.1 - 3.8e-47 158.7 13.2 6.4e-12 45.8 0.0 10.2 10 0 0 10 10 10 7 Cadherin domain Cadherin_3 PF16184.5 CBY20171.1 - 8.3e-08 32.2 30.3 0.021 14.8 0.2 8.7 9 0 0 9 9 9 5 Cadherin-like Cadherin_2 PF08266.12 CBY20171.1 - 0.016 15.0 0.3 11 6.0 0.0 4.5 5 0 0 5 5 5 0 Cadherin-like PP2C_2 PF13672.6 CBY20172.1 - 0.079 12.6 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Homeodomain PF00046.29 CBY20174.1 - 1.5e-18 66.4 11.8 2.1e-18 65.9 11.8 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY20174.1 - 0.091 12.7 2.0 0.21 11.5 2.0 1.7 1 1 0 1 1 1 0 Homeobox KN domain BPL_LplA_LipB PF03099.19 CBY20175.1 - 2.9e-05 24.0 0.0 6.9e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Metallophos PF00149.28 CBY20177.1 - 4.9e-39 135.0 0.1 6.1e-39 134.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBY20177.1 - 1.9e-21 76.2 1.5 3.3e-21 75.5 0.8 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain XRCC1_N PF01834.16 CBY20178.1 - 0.00066 19.7 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 XRCC1 N terminal domain zf_UBZ PF18439.1 CBY20178.1 - 0.046 13.3 1.7 3.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF3138 PF11336.8 CBY20178.1 - 0.48 9.0 3.3 0.72 8.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TRAF6_Z2 PF18048.1 CBY20178.1 - 1.6 8.9 5.2 33 4.7 0.0 3.4 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 DUF3043 PF11241.8 CBY20178.1 - 9.9 6.2 10.3 24 4.9 10.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PX PF00787.24 CBY20179.1 - 5e-20 71.6 2.7 1.5e-19 70.0 0.1 2.8 3 0 0 3 3 3 1 PX domain NPV_P10 PF05531.12 CBY20179.1 - 0.071 13.6 2.4 8 7.0 0.0 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 CBY20179.1 - 0.7 10.5 3.0 4.1 8.1 0.9 3.1 3 1 0 3 3 3 0 SlyX DUF3496 PF12001.8 CBY20179.1 - 1.4 9.4 11.1 4.1 7.8 0.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3496) FlaC_arch PF05377.11 CBY20179.1 - 1.6 9.2 9.0 36 4.8 0.1 4.5 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Muted PF14942.6 CBY20179.1 - 8.3 6.8 15.4 0.57 10.5 0.3 3.6 3 1 1 4 4 4 0 Organelle biogenesis, Muted-like protein Kinesin PF00225.23 CBY20180.1 - 2e-111 372.1 0.0 3.6e-111 371.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY20180.1 - 1.1e-23 83.8 0.1 3.4e-23 82.2 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 CBY20180.1 - 3.8e-22 79.3 2.3 1.7e-12 47.9 0.1 3.1 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 CBY20180.1 - 4.1e-14 53.5 0.0 1.8e-13 51.4 0.0 2.2 1 1 0 1 1 1 1 Kinesin protein KIF1B PF12423.8 CBY20180.1 - 1e-10 41.9 0.2 1e-10 41.9 0.2 2.5 2 0 0 2 2 2 1 Kinesin protein 1B Yop-YscD_cpl PF16697.5 CBY20180.1 - 0.0002 21.6 0.0 0.00097 19.4 0.0 2.1 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 CBY20180.1 - 0.0005 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain PP1c_bdg PF10488.9 CBY20180.1 - 0.33 10.4 11.7 10 5.5 9.6 2.5 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region CDT1_C PF16679.5 CBY20180.1 - 1.7 9.1 5.0 0.4 11.1 0.2 2.6 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain Methyltransf_25 PF13649.6 CBY20181.1 - 4.8e-09 36.8 0.2 3e-08 34.2 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBY20181.1 - 5.3e-08 32.6 1.5 8.2e-08 32.0 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CBY20181.1 - 7.3e-08 32.1 0.1 1.3e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CBY20181.1 - 2.9e-06 27.8 0.4 2.6e-05 24.8 0.1 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBY20181.1 - 1.4e-05 24.2 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.6 CBY20181.1 - 2.6e-05 24.1 0.0 5.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY20181.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY20181.1 - 0.0022 18.7 0.2 0.0064 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CBY20181.1 - 0.0025 17.2 0.1 0.0055 16.0 0.1 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CBY20181.1 - 0.0057 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 CBY20181.1 - 0.021 14.1 0.2 0.056 12.7 0.2 1.7 1 0 0 1 1 1 0 O-methyltransferase domain Cons_hypoth95 PF03602.15 CBY20181.1 - 0.035 13.7 0.1 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 CBY20181.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 CBY20181.1 - 0.078 13.1 0.3 0.3 11.2 0.1 2.1 2 1 0 2 2 2 0 FtsJ-like methyltransferase AlaDh_PNT_C PF01262.21 CBY20181.1 - 0.12 11.7 0.7 0.2 10.9 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ASXH PF13919.6 CBY20182.1 - 2.1e-28 99.0 0.8 4.2e-28 98.1 0.2 1.7 2 0 0 2 2 2 1 Asx homology domain Terminase_6C PF17289.2 CBY20182.1 - 0.14 12.2 0.1 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Terminase RNaseH-like domain zinc_ribbon_4 PF13717.6 CBY20183.1 - 0.14 12.1 1.3 0.34 10.9 1.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain UQ_con PF00179.26 CBY20184.1 - 2.6e-19 69.3 0.1 4.7e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme G8 PF10162.9 CBY20187.1 - 5.6e-17 62.0 0.0 1.3e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 G8 domain CBM_14 PF01607.24 CBY20188.1 - 3.9e-20 71.8 20.0 2e-12 47.1 3.8 3.2 3 0 0 3 3 3 2 Chitin binding Peritrophin-A domain STAT_bind PF02864.15 CBY20189.1 - 1.2e-49 168.2 0.6 1.2e-49 168.2 0.6 2.4 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 CBY20189.1 - 4.3e-46 156.9 24.2 8e-46 156.1 24.2 1.5 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.17 CBY20189.1 - 6.9e-39 133.1 0.0 6.9e-39 133.1 0.0 2.9 2 0 0 2 2 2 1 STAT protein, protein interaction domain SH2 PF00017.24 CBY20189.1 - 9.8e-08 32.0 0.1 4.7e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 SH2 domain hDGE_amylase PF14701.6 CBY20189.1 - 0.12 11.4 5.9 0.25 10.4 5.9 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain NAD_binding_1 PF00175.21 CBY20190.1 - 1.9e-29 102.5 0.0 2.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBY20190.1 - 4.2e-29 100.8 0.0 6.8e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBY20190.1 - 6.6e-05 23.1 0.0 0.00046 20.3 0.0 2.0 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CBY20190.1 - 0.096 12.9 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain MFS_1 PF07690.16 CBY20191.1 - 2.4e-12 46.5 24.1 1.6e-06 27.3 9.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfotransfer_2 PF03567.14 CBY20193.1 - 4e-11 43.3 0.8 5.4e-11 42.9 0.1 1.5 2 0 0 2 2 2 1 Sulfotransferase family Wx5_PLAF3D7 PF09688.10 CBY20193.1 - 0.0025 17.9 0.1 0.0047 16.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (Wx5_PLAF3D7) DUF3516 PF12029.8 CBY20193.1 - 0.091 11.8 0.5 0.12 11.4 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3516) gag_pre-integrs PF13976.6 CBY20193.1 - 0.15 12.0 1.5 0.89 9.5 0.3 2.2 2 0 0 2 2 2 0 GAG-pre-integrase domain PLA2_B PF01735.18 CBY20194.1 - 1.9e-55 188.2 0.0 2.3e-50 171.4 0.1 2.8 2 1 1 3 3 3 2 Lysophospholipase catalytic domain Patatin PF01734.22 CBY20194.1 - 0.028 14.6 0.2 9.2 6.4 0.1 2.5 2 0 0 2 2 2 0 Patatin-like phospholipase I-set PF07679.16 CBY20195.1 - 2.6e-24 85.1 0.3 6.5e-06 26.1 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY20195.1 - 1.4e-12 48.0 0.0 0.0084 16.7 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 CBY20195.1 - 0.013 15.6 0.9 8.2 6.7 0.1 3.9 5 0 0 5 5 5 0 Immunoglobulin domain Ig_2 PF13895.6 CBY20195.1 - 0.075 13.4 0.1 34 4.8 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin domain LolA_like PF17131.4 CBY20195.1 - 0.08 12.7 0.1 2.4 7.9 0.0 2.9 2 1 1 3 3 3 0 Outer membrane lipoprotein-sorting protein ChaC PF04752.12 CBY20196.1 - 6.1e-51 173.0 0.0 7.2e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein ANAPC4_WD40 PF12894.7 CBY20197.1 - 6e-15 55.3 1.3 0.00067 19.9 0.2 6.9 4 2 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY20197.1 - 2.3e-12 47.2 3.0 0.0019 19.0 0.0 8.3 9 1 0 9 9 9 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY20197.1 - 0.00043 19.4 0.0 0.14 11.1 0.0 3.1 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBY20197.1 - 0.0016 18.3 0.0 0.018 14.9 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CBY20197.1 - 0.038 13.9 0.7 0.16 11.9 0.1 2.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat GET2 PF08690.10 CBY20198.1 - 0.0072 16.0 10.7 0.0072 16.0 10.7 1.5 2 0 0 2 2 2 1 GET complex subunit GET2 TFIIF_alpha PF05793.12 CBY20198.1 - 0.048 12.2 1.0 0.067 11.8 1.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 CBY20198.1 - 0.06 13.1 1.4 0.095 12.4 1.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2_4 PF13894.6 CBY20198.1 - 0.11 13.4 7.8 6.1 8.0 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY20198.1 - 0.13 12.7 7.2 1.2 9.8 0.1 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-FCS PF06467.14 CBY20198.1 - 0.16 12.0 3.3 3.5 7.6 0.5 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.8 CBY20198.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding His_Me_b4a2 PF18275.1 CBY20198.1 - 1.4 9.1 4.2 19 5.4 0.2 3.2 3 0 0 3 3 3 0 His-Me finger endonuclease beta4-alpha2 domain DUF5611 PF18446.1 CBY20199.1 - 0.85 10.5 6.9 0.083 13.8 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5611) RasGAP_C PF03836.15 CBY20199.1 - 0.93 9.6 8.4 0.32 11.1 3.7 2.3 2 1 0 2 2 2 0 RasGAP C-terminus DUF4407 PF14362.6 CBY20199.1 - 5.6 6.2 8.8 0.56 9.5 4.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PHD PF00628.29 CBY20200.1 - 6.6e-12 45.1 4.9 1.7e-11 43.8 4.9 1.8 1 0 0 1 1 1 1 PHD-finger zf-RanBP PF00641.18 CBY20200.1 - 0.00011 21.5 8.8 0.0029 16.9 1.8 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others PHD_2 PF13831.6 CBY20200.1 - 0.0054 16.3 1.9 0.0054 16.3 1.9 2.3 2 0 0 2 2 2 1 PHD-finger Rubredoxin PF00301.20 CBY20200.1 - 0.02 14.9 5.9 0.75 9.9 0.3 2.5 2 0 0 2 2 2 0 Rubredoxin ATG11 PF10377.9 CBY20200.1 - 0.075 13.1 0.3 0.075 13.1 0.3 3.1 3 1 0 3 3 3 0 Autophagy-related protein 11 zf-ribbon_3 PF13248.6 CBY20200.1 - 0.59 9.6 3.4 1.6 8.3 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-MIZ PF02891.20 CBY20200.1 - 0.66 9.8 2.7 5.4 6.9 0.1 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 CBY20200.1 - 1.2 9.5 4.0 2.4 8.6 4.0 1.5 1 0 0 1 1 1 0 Ring finger domain zinc_ribbon_10 PF10058.9 CBY20200.1 - 1.8 8.4 5.4 12 5.7 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD_4 PF16866.5 CBY20200.1 - 6.8 6.9 8.2 25 5.1 0.1 3.3 2 1 0 2 2 2 0 PHD-finger MH2 PF03166.14 CBY20202.1 - 1e-53 182.4 2.2 1.9e-52 178.2 0.3 2.3 2 0 0 2 2 2 2 MH2 domain MH1 PF03165.16 CBY20202.1 - 7.8e-38 128.8 0.0 2.1e-37 127.5 0.0 1.8 1 0 0 1 1 1 1 MH1 domain JmjC PF02373.22 CBY20203.1 - 1.3e-28 99.7 0.3 3.1e-28 98.5 0.3 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF1712 PF08217.11 CBY20204.1 - 1.6e-22 79.7 0.5 1.8e-22 79.6 0.5 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) CpXC PF14353.6 CBY20204.1 - 0.046 13.8 0.0 0.32 11.1 0.0 1.9 1 1 0 2 2 2 0 CpXC protein WD40 PF00400.32 CBY20206.1 - 5.1e-21 74.6 11.9 6.5e-07 30.0 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20206.1 - 1.9e-07 31.3 0.3 0.81 10.0 0.1 4.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY20206.1 - 0.00083 18.8 0.0 0.039 13.3 0.0 2.3 1 1 1 3 3 3 1 WD40-like domain PQQ_2 PF13360.6 CBY20206.1 - 0.00097 18.8 0.1 0.01 15.4 0.1 2.1 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 CBY20206.1 - 0.0046 17.4 0.4 3.3 8.3 0.0 4.0 4 0 0 4 4 4 1 PQQ-like domain N_BRCA1_IG PF16158.5 CBY20207.1 - 9e-32 109.8 0.2 1.2e-31 109.4 0.2 1.2 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 CBY20207.1 - 2.3e-12 46.5 1.0 3.6e-12 45.9 1.0 1.3 1 0 0 1 1 1 1 UBA-like domain CARDB PF07705.11 CBY20207.1 - 4.2e-05 23.7 0.0 6.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 CARDB DUF3592 PF12158.8 CBY20207.1 - 0.06 13.4 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) TAP_C PF03943.13 CBY20207.1 - 0.069 12.8 0.2 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 TAP C-terminal domain DUF3951 PF13131.6 CBY20208.1 - 0.25 11.5 6.0 0.24 11.6 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3951) HTH_32 PF13565.6 CBY20209.1 - 0.025 15.2 0.3 0.034 14.8 0.3 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Cnn_1N PF07989.11 CBY20210.1 - 0.00091 19.3 5.0 0.00091 19.3 5.0 12.3 7 2 3 10 10 10 4 Centrosomin N-terminal motif 1 DUF2617 PF10936.8 CBY20210.1 - 1.5 8.9 4.3 2.4 8.2 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF2617 Phospholip_A2_1 PF00068.19 CBY20211.1 - 7.6e-18 65.0 11.8 7.6e-18 65.0 11.8 2.2 1 1 1 2 2 2 1 Phospholipase A2 EGF_3 PF12947.7 CBY20212.1 - 6.1e-05 23.1 2.0 0.00014 21.9 2.0 1.7 1 0 0 1 1 1 1 EGF domain EGF_CA PF07645.15 CBY20212.1 - 0.00049 20.2 1.9 0.0014 18.8 1.9 1.8 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.27 CBY20212.1 - 0.0034 17.7 0.7 0.01 16.1 0.7 1.9 1 0 0 1 1 1 1 EGF-like domain EGF_MSP1_1 PF12946.7 CBY20212.1 - 0.01 15.9 1.8 0.027 14.5 1.8 1.8 1 0 0 1 1 1 0 MSP1 EGF domain 1 hEGF PF12661.7 CBY20212.1 - 0.022 15.4 0.8 0.094 13.4 0.8 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF EphA2_TM PF14575.6 CBY20213.1 - 0.097 13.6 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 CBY20214.1 - 2.8e-65 220.3 0.0 4.4e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20214.1 - 2.2e-32 112.4 0.2 4.4e-32 111.4 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY20214.1 - 0.00011 21.6 1.1 0.0008 18.8 0.2 2.2 1 1 1 2 2 2 1 Kinase-like 4PPT_N PF17837.1 CBY20214.1 - 0.14 12.3 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Lsr2 PF11774.8 CBY20214.1 - 0.25 11.5 3.7 0.66 10.1 3.7 1.7 1 0 0 1 1 1 0 Lsr2 ICA69 PF04629.14 CBY20214.1 - 8.2 6.7 16.0 3.1 8.0 12.8 1.8 2 1 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain EF-hand_1 PF00036.32 CBY20215.1 - 2.2e-20 70.6 3.3 1.5e-06 27.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY20215.1 - 9.8e-19 67.6 2.1 2.6e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY20215.1 - 1.1e-14 53.0 2.2 4.3e-06 26.2 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBY20215.1 - 3.7e-13 49.1 2.5 5.8e-07 29.3 0.1 3.2 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY20215.1 - 5e-11 41.6 3.9 0.00075 18.9 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 CBY20215.1 - 4.5e-05 23.3 0.4 0.22 11.5 0.1 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CBY20215.1 - 0.00016 21.8 0.5 0.056 13.6 0.0 2.8 2 1 0 2 2 2 1 Dockerin type I domain EF-hand_11 PF08976.11 CBY20215.1 - 0.00017 22.4 0.0 0.00038 21.3 0.0 1.5 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY20215.1 - 0.004 17.4 0.0 0.42 11.0 0.0 2.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 CBY20215.1 - 0.14 10.7 0.0 1.1 7.7 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5580) zf_Hakai PF18408.1 CBY20216.1 - 2.3e-06 27.2 0.0 5.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 CBY20216.1 - 0.0026 17.9 3.3 0.0049 17.0 0.1 2.2 2 0 0 2 2 2 1 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 CBY20216.1 - 0.033 15.0 0.1 0.13 13.2 0.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger RGS PF00615.19 CBY20217.1 - 4.4e-17 62.4 7.4 3.9e-09 36.8 0.9 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain ARL2_Bind_BART PF11527.8 CBY20217.1 - 0.0052 16.9 0.8 0.15 12.1 0.0 3.2 2 1 1 3 3 3 1 The ARF-like 2 binding protein BART 4HB_MCP_1 PF12729.7 CBY20217.1 - 0.034 13.7 1.1 0.062 12.8 1.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Daxx PF03344.15 CBY20217.1 - 0.16 12.1 1.2 5.4 7.2 0.0 3.3 4 0 0 4 4 4 0 Daxx N-terminal Rassf1C-interacting domain MAP65_ASE1 PF03999.12 CBY20218.1 - 2.1e-65 221.6 34.2 2.9e-65 221.1 34.2 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) ECH_2 PF16113.5 CBY20218.1 - 0.53 9.7 3.6 0.34 10.3 0.8 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase DAD PF02109.16 CBY20219.1 - 1.9e-43 147.2 2.8 2.2e-43 147.0 2.8 1.1 1 0 0 1 1 1 1 DAD family YIF1 PF03878.15 CBY20219.1 - 0.00049 19.7 0.3 0.00053 19.6 0.3 1.1 1 0 0 1 1 1 1 YIF1 NuA4 PF09340.10 CBY20220.1 - 3.6e-20 71.6 0.9 4.5e-20 71.3 0.9 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 HRM PF02793.22 CBY20221.1 - 0.0017 18.6 0.5 0.003 17.8 0.5 1.4 1 0 0 1 1 1 1 Hormone receptor domain SCIMP PF15050.6 CBY20221.1 - 0.0056 17.1 0.0 0.0082 16.6 0.0 1.2 1 0 0 1 1 1 1 SCIMP protein LRR19-TM PF15176.6 CBY20221.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Conotoxin PF02950.17 CBY20221.1 - 0.023 15.7 0.6 0.48 11.5 0.0 2.1 2 0 0 2 2 2 0 Conotoxin Amnionless PF14828.6 CBY20221.1 - 0.044 12.6 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 Amnionless SieB PF14163.6 CBY20221.1 - 0.049 13.1 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B Vpu PF00558.19 CBY20221.1 - 0.064 13.0 0.3 0.093 12.5 0.3 1.2 1 0 0 1 1 1 0 Vpu protein WBP-1 PF11669.8 CBY20221.1 - 0.079 13.6 0.2 0.095 13.3 0.2 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 Orthoreo_P10 PF07204.11 CBY20221.1 - 0.081 12.9 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 LYRIC PF15686.5 CBY20221.1 - 0.084 12.4 0.2 0.18 11.3 0.0 1.6 1 1 1 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family DUF2207 PF09972.9 CBY20221.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NPM1-C PF16276.5 CBY20224.1 - 1.6e-05 24.8 1.8 0.0029 17.5 0.0 2.5 2 0 0 2 2 2 2 Nucleophosmin C-terminal domain DUF3884 PF13024.6 CBY20224.1 - 0.017 14.7 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) RVT_1 PF00078.27 CBY20225.1 - 1.1e-10 41.5 0.0 2.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CBY20225.1 - 4.1e-09 36.4 0.0 1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY20225.1 - 3e-06 27.5 0.0 1e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CBY20225.1 - 1.1e-05 25.9 0.0 4.1e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CBY20225.1 - 0.0042 17.7 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 CBY20225.1 - 0.0099 16.0 0.1 0.025 14.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain BTG PF07742.12 CBY20225.1 - 0.064 13.1 0.3 0.39 10.6 0.1 2.4 2 0 0 2 2 2 0 BTG family RNase_T PF00929.24 CBY20227.1 - 1.6e-10 41.8 0.1 3.3e-10 40.7 0.1 1.5 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CBY20227.1 - 0.0002 21.1 0.3 0.001 18.8 0.3 2.0 1 1 0 1 1 1 1 3'-5' exonuclease DUF4490 PF14892.6 CBY20228.1 - 9.5e-09 35.2 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) KH_1 PF00013.29 CBY20230.1 - 0.00069 19.4 0.3 0.00074 19.3 0.3 1.1 1 0 0 1 1 1 1 KH domain ASH PF15780.5 CBY20231.1 - 0.01 16.1 0.0 58 4.0 0.0 3.7 3 0 0 3 3 3 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ASH PF15780.5 CBY20232.1 - 4.4e-14 52.5 0.1 0.00013 22.2 0.0 3.6 3 0 0 3 3 3 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 CBY20232.1 - 3.7e-13 49.3 0.1 9.9e-05 22.3 0.0 3.6 3 1 0 3 3 3 3 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 CBY20232.1 - 6.8e-08 32.3 0.6 0.00076 19.3 0.1 3.3 3 0 0 3 3 3 2 MSP (Major sperm protein) domain PapD-like PF14874.6 CBY20232.1 - 0.0014 18.7 0.1 3 8.1 0.0 3.3 4 0 0 4 4 4 2 Flagellar-associated PapD-like Tim54 PF11711.8 CBY20232.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM154 PF15102.6 CBY20232.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family NifU_N PF01592.16 CBY20232.1 - 0.18 12.0 0.1 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 NifU-like N terminal domain DNA_pol3_beta_3 PF02768.15 CBY20233.1 - 0.089 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain SIS PF01380.22 CBY20234.1 - 8.2e-55 184.2 0.0 5.2e-33 113.7 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CBY20234.1 - 2.1e-15 57.1 0.0 4.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CBY20234.1 - 2.6e-10 40.3 0.0 5.5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.6 CBY20234.1 - 7.5e-05 22.8 0.1 0.0006 19.8 0.0 2.4 1 1 1 2 2 2 1 SIS domain GATase_4 PF13230.6 CBY20234.1 - 0.00011 21.2 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HMG_box PF00505.19 CBY20236.1 - 3e-16 59.6 3.4 6.6e-16 58.5 3.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY20236.1 - 6.5e-09 36.3 1.9 1.9e-08 34.8 1.9 1.8 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 CBY20236.1 - 0.0011 18.3 0.9 0.0019 17.5 0.9 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Frag1 PF10277.9 CBY20238.1 - 1.8e-34 119.2 13.2 2.2e-34 118.9 13.2 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family FERM_C PF09380.10 CBY20239.1 - 1.7e-21 76.4 0.1 4.1e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CBY20239.1 - 5.5e-19 68.7 0.1 9.7e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CBY20239.1 - 4.8e-11 42.5 0.3 1.2e-10 41.2 0.3 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 CBY20239.1 - 9.8e-05 22.4 11.7 9.8e-05 22.4 11.7 1.8 2 0 0 2 2 2 1 FERM adjacent (FA) Tantalus PF15386.6 CBY20241.1 - 0.0052 16.9 0.5 0.0052 16.9 0.5 2.1 2 0 0 2 2 2 1 Drosophila Tantalus-like DUF1730 PF08331.10 CBY20241.1 - 0.093 12.6 0.1 0.82 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) Ribonuclease_3 PF00636.26 CBY20242.1 - 4.6e-33 114.0 0.1 3.5e-15 56.5 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CBY20242.1 - 7.4e-17 61.7 0.0 3.6e-08 33.6 0.0 4.4 4 0 0 4 4 4 3 Ribonuclease-III-like DUF3113 PF11310.8 CBY20242.1 - 0.061 13.3 0.3 0.21 11.6 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Ntox44 PF15607.6 CBY20242.1 - 0.091 13.1 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 Bacterial toxin 44 Peptidase_M1 PF01433.20 CBY20243.1 - 2.3e-49 167.9 1.7 2.9e-49 167.6 0.5 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY20243.1 - 3.1e-25 89.4 0.2 5.1e-25 88.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain RepA_N PF06970.11 CBY20243.1 - 0.038 13.9 1.3 2.6 8.1 0.1 2.6 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus DUF1360 PF07098.11 CBY20243.1 - 0.17 11.8 0.2 0.4 10.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Ion_trans PF00520.31 CBY20245.1 - 2.8e-21 75.9 16.4 5e-21 75.0 16.4 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY20245.1 - 2e-10 40.6 0.0 4.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CBY20245.1 - 5.3e-09 35.9 1.6 5.3e-09 35.9 1.6 2.2 2 0 0 2 2 2 1 Ion channel PAS_9 PF13426.7 CBY20245.1 - 1.4e-08 34.9 0.1 1.1e-07 32.1 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 CBY20245.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CBY20245.1 - 0.029 14.4 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.12 CBY20245.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 PAS fold CLZ PF16526.5 CBY20245.1 - 0.06 13.7 0.7 0.16 12.4 0.7 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2894 PF11445.8 CBY20245.1 - 0.069 13.6 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Cupin_3 PF05899.12 CBY20245.1 - 0.13 11.9 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1428 PF07237.11 CBY20245.1 - 0.17 12.1 0.4 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) Trypsin PF00089.26 CBY20246.1 - 5.4e-38 131.0 0.0 6.6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY20246.1 - 0.002 19.0 0.0 0.004 18.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY20246.1 - 0.046 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Laminin_N PF00055.17 CBY20247.1 - 1.3e-76 257.2 0.6 7.5e-76 254.8 0.6 2.5 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CBY20247.1 - 5.5e-74 244.1 221.8 2e-11 43.8 12.4 11.4 11 0 0 11 11 11 10 Laminin EGF domain Laminin_B PF00052.18 CBY20247.1 - 2.6e-14 53.3 0.0 5.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Laminin B (Domain IV) DUF745 PF05335.13 CBY20247.1 - 0.00049 19.9 3.4 0.00049 19.9 3.4 5.4 2 2 5 7 7 7 1 Protein of unknown function (DUF745) DUF3921 PF13060.6 CBY20247.1 - 0.17 12.0 0.6 3.8 7.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) SmAKAP PF15127.6 CBY20247.1 - 1.9 9.8 0.0 1.9 9.8 0.0 3.7 2 1 0 3 3 3 0 Small membrane A-kinase anchor protein DASH_Dam1 PF08653.10 CBY20247.1 - 1.9 8.4 7.4 18 5.2 0.1 4.3 3 1 1 4 4 4 0 DASH complex subunit Dam1 ApoO PF09769.9 CBY20247.1 - 4.1 7.4 8.6 8.3 6.4 0.1 4.0 3 1 0 3 3 3 0 Apolipoprotein O LRR_4 PF12799.7 CBY20248.1 - 5.1e-19 68.1 30.4 1.8e-06 28.1 2.2 6.4 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY20248.1 - 3e-15 56.1 13.5 6.1e-12 45.4 0.5 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 CBY20248.1 - 7e-15 54.5 24.7 2e-06 27.5 3.2 5.5 4 1 1 6 6 6 4 Leucine rich repeat Terminase_2 PF03592.16 CBY20248.1 - 0.021 15.3 0.1 0.051 14.0 0.1 1.6 1 0 0 1 1 1 0 Terminase small subunit FRP PF18032.1 CBY20248.1 - 0.12 13.0 5.1 0.47 11.1 0.0 3.5 2 2 2 4 4 4 0 Photoprotection regulator fluorescence recovery protein LRR_6 PF13516.6 CBY20248.1 - 1.3 9.2 0.0 1.3 9.2 0.0 7.5 8 1 1 9 9 9 0 Leucine Rich repeat Glyco_hydro_30 PF02055.16 CBY20250.1 - 1.7e-93 313.4 0.6 2e-93 313.1 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Redoxin PF08534.10 CBY20250.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Redoxin MerR_1 PF13411.6 CBY20250.1 - 0.11 12.6 0.1 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 MerR HTH family regulatory protein NHL PF01436.21 CBY20251.1 - 2.6e-08 33.5 1.3 0.00024 21.0 0.0 3.7 3 0 0 3 3 3 2 NHL repeat DUF5128 PF17170.4 CBY20251.1 - 0.012 14.8 0.5 0.025 13.7 0.5 1.5 1 0 0 1 1 1 0 6-bladed beta-propeller Phytase-like PF13449.6 CBY20251.1 - 0.072 13.0 0.0 0.57 10.1 0.0 2.0 1 1 0 2 2 2 0 Esterase-like activity of phytase SGL PF08450.12 CBY20251.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region zf-C2H2_jaz PF12171.8 CBY20252.1 - 0.0062 16.8 1.8 0.021 15.1 1.8 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 CBY20252.1 - 0.023 13.9 7.2 0.025 13.8 0.7 2.5 2 0 0 2 2 2 0 Putative actin-like family zf-C2H2_4 PF13894.6 CBY20252.1 - 0.087 13.7 1.3 0.65 11.0 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1612 PF07756.12 CBY20252.1 - 0.12 12.7 0.7 0.35 11.1 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) HMG_box PF00505.19 CBY20253.1 - 1.7e-23 82.8 4.6 1.7e-23 82.8 4.6 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box Rtt106 PF08512.12 CBY20253.1 - 3.5e-23 81.8 0.1 1.4e-22 79.9 0.1 2.2 1 1 1 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 CBY20253.1 - 7.1e-23 80.3 0.1 2.1e-22 78.8 0.1 1.9 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 CBY20253.1 - 1.7e-21 76.5 4.2 2.1e-18 66.5 0.7 3.4 2 1 1 3 3 3 1 POB3-like N-terminal PH domain HMG_box_2 PF09011.10 CBY20253.1 - 1.7e-18 67.0 4.9 1.7e-18 67.0 4.9 3.2 3 0 0 3 3 3 1 HMG-box domain Vps36_ESCRT-II PF11605.8 CBY20253.1 - 0.079 13.2 0.1 0.71 10.1 0.1 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 YABBY PF04690.13 CBY20253.1 - 0.22 12.1 14.8 0.05 14.2 9.8 2.5 1 1 1 2 2 2 0 YABBY protein Ribosomal_L7Ae PF01248.26 CBY20254.1 - 5.2e-24 83.8 0.4 6.4e-24 83.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CBY20254.1 - 0.0088 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain DUF4064 PF13273.6 CBY20256.1 - 0.077 13.3 4.3 0.26 11.6 4.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Tetraspanin PF00335.20 CBY20256.1 - 0.085 12.5 13.7 0.018 14.7 7.4 2.0 1 1 1 2 2 2 0 Tetraspanin family Membralin PF09746.9 CBY20256.1 - 0.21 10.6 0.4 1.3 8.0 0.0 2.0 2 0 0 2 2 2 0 Tumour-associated protein U79_P34 PF03064.16 CBY20256.1 - 0.27 10.5 4.5 0.46 9.8 4.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4186 PF13811.6 CBY20257.1 - 0.0054 16.7 0.0 0.0071 16.4 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4186) GSIII_N PF12437.8 CBY20257.1 - 0.048 13.3 0.2 0.13 11.9 0.1 1.7 1 1 1 2 2 2 0 Glutamine synthetase type III N terminal Membralin PF09746.9 CBY20258.1 - 0.11 11.5 0.3 0.92 8.5 0.0 2.0 2 0 0 2 2 2 0 Tumour-associated protein U79_P34 PF03064.16 CBY20258.1 - 0.2 11.0 4.6 0.32 10.3 4.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-CXXC PF02008.20 CBY20259.1 - 1.1e-23 82.9 41.7 5e-14 52.1 19.4 2.7 3 0 0 3 3 3 2 CXXC zinc finger domain FMO-like PF00743.19 CBY20261.1 - 6.2e-13 48.0 1.8 8e-12 44.3 2.6 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CBY20261.1 - 1.2e-05 24.6 0.0 0.00027 20.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CBY20261.1 - 0.012 15.9 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DuoxA PF10204.9 CBY20262.1 - 0.0071 15.4 2.1 0.0086 15.1 2.1 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor Carn_acyltransf PF00755.20 CBY20264.1 - 6.8e-18 64.6 0.0 7.4e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.20 CBY20265.1 - 4.5e-129 431.7 0.9 5.8e-129 431.4 0.9 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SIMPL PF04402.14 CBY20267.1 - 8.4e-15 55.8 1.5 1.1e-14 55.4 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) CBM_21 PF03370.13 CBY20267.1 - 0.061 13.5 1.0 0.1 12.8 1.0 1.5 1 1 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) Chromo_shadow PF01393.19 CBY20268.1 - 1.7e-15 56.8 0.3 1.8e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 CBY20268.1 - 3.2e-15 55.8 0.9 1.9e-13 50.1 0.8 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PhoQ_Sensor PF08918.10 CBY20268.1 - 0.19 11.5 1.7 6.5 6.6 0.2 2.5 2 0 0 2 2 2 0 PhoQ Sensor tRNA-synt_2d PF01409.20 CBY20270.1 - 9e-88 293.9 0.0 1.1e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 CBY20270.1 - 9.1e-12 44.9 0.1 5.2e-08 32.6 0.0 2.5 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 CBY20270.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 CBY20270.1 - 0.00021 20.5 0.1 0.0007 18.8 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) ADPrib_exo_Tox PF03496.14 CBY20270.1 - 0.086 12.2 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme TPR_2 PF07719.17 CBY20271.1 - 1.8e-10 40.1 12.8 0.057 13.6 0.2 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBY20271.1 - 5.6e-09 35.6 0.0 0.13 12.0 0.1 4.8 5 0 0 5 5 5 3 TPR repeat TPR_19 PF14559.6 CBY20271.1 - 2.7e-08 34.2 5.9 0.0011 19.4 0.1 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY20271.1 - 3.4e-08 33.6 4.5 2.3 9.3 0.1 6.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY20271.1 - 1.9e-07 30.6 9.9 0.021 14.6 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY20271.1 - 4.1e-07 30.5 2.1 0.026 15.2 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY20271.1 - 4.3e-07 29.6 7.9 2.9 8.3 0.0 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY20271.1 - 4e-05 23.8 3.5 0.0025 18.1 0.2 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY20271.1 - 0.0011 18.8 0.0 22 5.4 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 CBY20271.1 - 0.0022 18.4 0.9 0.086 13.3 0.0 3.2 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 CBY20271.1 - 0.0069 17.0 0.3 20 6.1 0.0 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY20271.1 - 0.014 15.8 4.1 0.14 12.6 0.2 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY20271.1 - 0.034 14.0 5.5 3.6 7.6 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY20271.1 - 0.038 14.1 0.1 1.5 9.0 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3552 PF12072.8 CBY20272.1 - 0.00013 21.5 4.7 0.00017 21.1 4.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Pkinase PF00069.25 CBY20273.1 - 3.7e-62 210.1 0.0 4.5e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20273.1 - 8.3e-42 143.3 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY20273.1 - 3.7e-05 23.2 0.0 6.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY20273.1 - 0.00015 20.7 0.6 0.00043 19.2 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 CBY20273.1 - 0.0005 20.1 0.1 0.54 10.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family MRP-S31 PF15433.6 CBY20274.1 - 2e-24 86.8 2.8 2.9e-24 86.3 2.8 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 DOT1 PF08123.13 CBY20275.1 - 0.0077 15.8 0.0 0.072 12.6 0.0 2.0 2 0 0 2 2 2 1 Histone methylation protein DOT1 GTP_EFTU PF00009.27 CBY20276.1 - 3e-39 134.6 0.0 4.8e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CBY20276.1 - 4.2e-32 111.3 7.8 8.6e-32 110.3 7.8 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CBY20276.1 - 7.5e-23 80.6 0.0 1.6e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CBY20276.1 - 4.6e-22 77.9 0.0 1e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CBY20276.1 - 3.4e-08 33.4 0.0 9.5e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CBY20276.1 - 8.5e-08 32.5 0.0 2.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY20276.1 - 0.00086 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CBY20276.1 - 0.067 12.8 0.0 0.26 10.9 0.0 2.0 1 1 0 1 1 1 0 Ras family VHS PF00790.19 CBY20277.1 - 2.3e-23 82.6 0.0 7.4e-23 81.0 0.0 1.9 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 CBY20277.1 - 1.2e-11 44.9 0.4 2.3e-11 44.0 0.4 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 CBY20277.1 - 1.5e-10 40.5 4.2 4.2e-10 39.1 4.2 1.8 1 0 0 1 1 1 1 GGA N-GAT domain GAT PF03127.14 CBY20277.1 - 5.3e-07 29.9 4.2 2.4e-06 27.7 0.3 2.5 2 0 0 2 2 2 1 GAT domain Holin_BhlA PF10960.8 CBY20277.1 - 0.084 12.8 0.5 0.25 11.3 0.5 1.7 1 0 0 1 1 1 0 BhlA holin family Cyt_c_ox_IV PF12270.8 CBY20278.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV ECSCR PF15820.5 CBY20278.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF1143 PF06608.11 CBY20279.1 - 1.7e-28 99.5 3.4 2.5e-28 99.0 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) LrgB PF04172.16 CBY20280.1 - 0.0075 15.8 2.7 0.011 15.3 2.7 1.3 1 0 0 1 1 1 1 LrgB-like family DUF4199 PF13858.6 CBY20280.1 - 0.063 13.7 6.6 0.025 15.0 4.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) CDC50 PF03381.15 CBY20281.1 - 1.2e-83 280.9 0.1 1.6e-83 280.5 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.6 CBY20281.1 - 2.6 8.8 6.5 0.43 11.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) CCDC92 PF14916.6 CBY20282.1 - 1.4e-11 44.0 5.3 1.8e-11 43.6 1.1 2.3 2 0 0 2 2 2 1 Coiled-coil domain of unknown function APG6_N PF17675.1 CBY20282.1 - 0.13 12.8 10.7 0.36 11.4 0.8 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 CBY20282.1 - 0.15 12.1 0.3 0.15 12.1 0.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 CBY20282.1 - 0.42 11.3 5.4 1.7 9.3 0.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 CBY20282.1 - 0.46 11.0 11.4 1.5 9.3 2.0 2.8 2 1 1 3 3 3 0 Cell division protein ZapB WD40_alt PF14077.6 CBY20282.1 - 0.55 10.2 0.1 0.55 10.2 0.1 2.7 3 0 0 3 3 3 0 Alternative WD40 repeat motif Cnn_1N PF07989.11 CBY20282.1 - 1 9.6 8.4 0.55 10.4 1.2 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DMPK_coil PF08826.10 CBY20282.1 - 1.6 8.9 11.4 3.2 7.9 1.2 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like bZIP_1 PF00170.21 CBY20282.1 - 1.8 8.7 10.1 1.4 9.1 2.8 2.9 3 0 0 3 3 3 0 bZIP transcription factor DivIC PF04977.15 CBY20282.1 - 2.8 7.8 7.4 3 7.7 0.7 2.6 2 1 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 CBY20282.1 - 3.6 8.1 5.7 5.1 7.6 1.0 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FAA_hydrolase PF01557.18 CBY20284.1 - 2.5e-31 109.0 0.0 3.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Dynactin_p22 PF07426.11 CBY20285.1 - 2.8e-08 33.8 1.0 2.8e-08 33.8 1.0 1.4 1 1 0 1 1 1 1 Dynactin subunit p22 SlyX PF04102.12 CBY20285.1 - 0.014 16.0 1.0 5 7.8 0.3 2.6 1 1 2 3 3 3 0 SlyX DUF2540 PF10802.8 CBY20285.1 - 0.044 13.9 0.5 0.061 13.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) DUF948 PF06103.11 CBY20285.1 - 0.061 13.6 0.0 1.1 9.6 0.0 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Sulfotransfer_2 PF03567.14 CBY20285.1 - 0.089 12.7 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family TRPM_tetra PF16519.5 CBY20285.1 - 0.37 10.9 2.7 9.1 6.5 0.3 2.6 1 1 2 3 3 3 0 Tetramerisation domain of TRPM TTL PF03133.15 CBY20286.1 - 3.5e-105 351.4 2.3 4.4e-105 351.0 2.3 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY20286.1 - 4.3e-08 32.7 0.0 1.2e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY20286.1 - 0.00012 21.5 0.0 0.00089 18.6 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Inhibitor_I66 PF16850.5 CBY20286.1 - 0.025 14.5 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I66 RimK PF08443.11 CBY20286.1 - 0.083 12.5 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Ish1 PF10281.9 CBY20286.1 - 0.094 13.0 2.1 2.9 8.3 0.0 3.4 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Tropomyosin_1 PF12718.7 CBY20287.1 - 0.011 15.9 6.2 0.018 15.2 6.2 1.3 1 0 0 1 1 1 0 Tropomyosin like UPF0561 PF10573.9 CBY20287.1 - 0.05 13.7 1.6 0.1 12.7 0.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 DASH_Spc19 PF08287.11 CBY20287.1 - 0.2 11.6 4.6 0.2 11.6 3.3 1.7 1 1 1 2 2 2 0 Spc19 COX5B PF01215.19 CBY20288.1 - 0.0063 16.2 0.0 0.019 14.7 0.0 1.7 1 1 1 2 2 2 1 Cytochrome c oxidase subunit Vb Tfb2 PF03849.14 CBY20289.1 - 3.8e-97 325.5 0.8 5.8e-97 324.8 0.8 1.3 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CBY20289.1 - 9.4e-24 83.6 1.9 3.4e-23 81.8 1.5 2.3 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CBY20289.1 - 0.0001 22.4 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LRR_6 PF13516.6 CBY20290.1 - 3.4e-24 82.8 36.2 0.0062 16.5 0.0 13.1 14 0 0 14 14 14 8 Leucine Rich repeat LRR_1 PF00560.33 CBY20290.1 - 4.2e-09 35.7 14.6 35 5.5 0.0 12.1 12 0 0 12 12 12 0 Leucine Rich Repeat LRR_4 PF12799.7 CBY20290.1 - 1.4e-08 34.9 32.7 0.001 19.4 0.5 10.8 8 3 5 13 13 13 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY20290.1 - 0.00059 19.6 11.5 0.0032 17.2 2.1 8.9 8 2 2 10 10 10 4 Leucine rich repeat RanGAP1_C PF07834.11 CBY20290.1 - 0.0047 16.6 0.1 0.0094 15.6 0.1 1.5 1 0 0 1 1 1 1 RanGAP1 C-terminal domain Lactamase_B_5 PF14597.6 CBY20290.1 - 0.027 14.0 1.0 0.046 13.2 0.3 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily T-box PF00907.22 CBY20291.1 - 1.5e-73 247.0 0.2 2e-73 246.6 0.2 1.1 1 0 0 1 1 1 1 T-box RanGAP1_C PF07834.11 CBY20292.1 - 3.9e-05 23.3 0.0 4.4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 RanGAP1 C-terminal domain Synaptobrevin PF00957.21 CBY20293.1 - 6.4e-31 106.0 4.1 7.2e-31 105.8 4.1 1.0 1 0 0 1 1 1 1 Synaptobrevin CEND1 PF15677.5 CBY20293.1 - 0.013 16.0 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Foamy_virus_ENV PF03408.14 CBY20293.1 - 0.015 13.2 0.0 0.015 13.2 0.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein ASFV_J13L PF05568.11 CBY20293.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Asp5 PF17000.5 CBY20293.1 - 0.028 14.6 0.1 0.045 13.9 0.1 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 ODV-E18 PF10717.9 CBY20293.1 - 0.032 14.1 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 CD34_antigen PF06365.12 CBY20293.1 - 0.034 13.7 0.2 0.041 13.4 0.2 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family MCU PF04678.13 CBY20293.1 - 0.044 13.9 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Sigma_reg_N PF13800.6 CBY20293.1 - 0.066 13.5 0.6 0.12 12.7 0.6 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SP_C-Propep PF08999.10 CBY20293.1 - 0.066 13.0 0.6 0.12 12.1 0.6 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Fzo_mitofusin PF04799.13 CBY20293.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region RIFIN PF02009.16 CBY20293.1 - 0.081 12.8 0.1 0.099 12.5 0.1 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 CBY20293.1 - 0.13 12.6 1.2 0.18 12.1 1.2 1.3 1 1 0 1 1 1 0 Orf78 (ac78) Glycophorin_A PF01102.18 CBY20293.1 - 0.15 12.3 0.9 0.19 11.9 0.9 1.4 1 1 0 1 1 1 0 Glycophorin A ECSCR PF15820.5 CBY20293.1 - 0.25 11.2 3.2 0.5 10.2 1.9 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator FeoB_associated PF12669.7 CBY20293.1 - 0.29 11.6 2.1 0.47 10.9 2.1 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2937 PF11157.8 CBY20293.1 - 0.43 10.3 3.5 0.17 11.5 1.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) XhlA PF10779.9 CBY20293.1 - 0.66 10.2 5.8 2.3 8.5 5.8 1.9 1 1 0 1 1 1 0 Haemolysin XhlA GP41 PF00517.17 CBY20293.1 - 0.83 9.5 8.2 3.6 7.4 8.2 1.8 1 1 0 1 1 1 0 Retroviral envelope protein IBN_N PF03810.19 CBY20294.1 - 3.7e-11 42.8 0.2 4.1e-10 39.4 0.0 3.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CBY20294.1 - 1.2e-05 25.4 4.8 5.9e-05 23.2 0.0 3.9 3 2 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 CBY20294.1 - 0.0001 22.2 0.6 19 5.8 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat MMS19_C PF12460.8 CBY20294.1 - 0.00044 19.5 0.6 1.2 8.1 0.0 3.0 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal DCB PF16213.5 CBY20294.1 - 0.019 14.6 0.0 0.32 10.7 0.0 2.7 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 SPDY PF03771.16 CBY20294.1 - 0.052 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF317) HEAT_EZ PF13513.6 CBY20294.1 - 0.16 12.5 1.6 46 4.7 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat DUF2729 PF10870.8 CBY20294.1 - 8.3 6.4 7.1 0.33 10.8 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2729) Pox_D5 PF03288.16 CBY20295.1 - 4.9 7.7 8.6 1 9.9 1.0 2.7 2 1 0 2 2 2 0 Poxvirus D5 protein-like XPG_N PF00752.17 CBY20296.1 - 1.3e-07 32.0 0.1 3.2e-06 27.5 0.1 2.8 1 1 0 1 1 1 1 XPG N-terminal domain STI1 PF17830.1 CBY20296.1 - 0.0013 18.6 0.2 0.98 9.4 0.0 2.8 2 0 0 2 2 2 2 STI1 domain XPG_I PF00867.18 CBY20298.1 - 1.6e-13 50.8 1.1 6.6e-13 48.8 0.0 2.7 3 1 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 CBY20298.1 - 2.9e-05 24.6 0.2 0.00081 20.0 0.0 2.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF1344 PF07076.11 CBY20298.1 - 0.036 14.0 0.1 0.09 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF424 PF04242.13 CBY20298.1 - 0.13 12.6 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF424) RNase_Zc3h12a PF11977.8 CBY20299.1 - 1.8e-28 99.3 0.0 3.1e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Peripla_BP_3 PF13377.6 CBY20299.1 - 0.0014 19.0 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 2 Periplasmic binding protein-like domain Glycos_transf_1 PF00534.20 CBY20300.1 - 8.6e-16 57.9 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY20300.1 - 3.7e-09 36.8 0.0 4.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CBY20300.1 - 1.1e-06 29.2 0.0 1.6e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 PRP1_N PF06424.12 CBY20302.1 - 4.6e-54 182.8 4.3 4.6e-54 182.8 4.3 2.3 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CBY20302.1 - 7.2e-28 94.9 24.4 0.0022 18.7 0.4 13.4 5 3 9 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 CBY20302.1 - 1.9e-24 86.0 13.5 1.9e-06 28.3 0.2 9.1 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBY20302.1 - 2.1e-14 53.9 0.0 0.027 15.1 0.1 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY20302.1 - 2.7e-11 42.8 4.7 0.015 15.4 0.0 8.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY20302.1 - 3.9e-11 42.5 0.3 0.048 14.1 0.1 8.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY20302.1 - 1.2e-08 34.4 11.2 0.52 10.6 0.0 9.7 12 1 0 13 13 12 2 Tetratricopeptide repeat Suf PF05843.14 CBY20302.1 - 1e-05 25.7 2.4 0.0032 17.5 0.0 3.9 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_1 PF00515.28 CBY20302.1 - 1.6e-05 24.5 0.2 1.7 8.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 CBY20302.1 - 0.00053 19.9 1.4 4.2 7.4 0.1 4.0 3 1 1 4 4 4 1 ZNRF-3 Ectodomain TPR_11 PF13414.6 CBY20302.1 - 0.0012 18.5 0.0 2.2 8.0 0.0 4.7 3 1 1 4 4 4 1 TPR repeat ChAPs PF09295.10 CBY20302.1 - 0.018 14.0 4.6 3 6.7 0.1 3.0 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Piwi PF02171.17 CBY20303.1 - 1.1e-74 251.5 1.9 1.6e-74 250.9 1.9 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CBY20303.1 - 3.8e-23 81.8 0.2 8.8e-23 80.6 0.2 1.7 1 0 0 1 1 1 1 PAZ domain OmpA_like PF16961.5 CBY20303.1 - 0.0036 17.0 0.2 0.01 15.5 0.1 1.7 2 0 0 2 2 2 1 Putative OmpA-OmpF-like porin family FliD_C PF07195.12 CBY20303.1 - 0.041 13.3 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Tricorn_C1 PF14684.6 CBY20303.1 - 0.096 12.8 0.5 0.57 10.3 0.4 2.3 2 0 0 2 2 2 0 Tricorn protease C1 domain CH PF00307.31 CBY20304.1 - 2.1e-15 56.9 0.1 3.8e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Smoothelin PF12510.8 CBY20304.1 - 9.7e-11 41.5 2.8 2.9e-10 40.0 2.8 1.8 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein CAMSAP_CH PF11971.8 CBY20304.1 - 2.1e-06 27.5 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain GED PF02212.18 CBY20304.1 - 0.097 12.8 0.7 0.25 11.5 0.7 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain GREB1 PF15782.5 CBY20304.1 - 3.8 4.5 17.7 4.8 4.2 17.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF772 PF05598.11 CBY20308.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Transposase domain (DUF772) DUF2624 PF11116.8 CBY20308.1 - 0.11 13.4 2.7 0.29 12.0 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) DUF829 PF05705.14 CBY20310.1 - 1.6e-15 57.7 0.0 8.3e-15 55.3 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) IF4E PF01652.18 CBY20311.1 - 3.5e-42 143.9 0.4 4.5e-42 143.5 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 CBY20312.1 - 7.6e-59 199.2 0.0 1.5e-58 198.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20312.1 - 5.6e-33 114.3 0.0 1.2e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase zinc_ribbon_2 PF13240.6 CBY20313.1 - 0.17 11.7 3.6 0.73 9.6 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain TSP_1 PF00090.19 CBY20313.1 - 0.72 10.1 19.2 0.75 10.1 6.0 2.9 1 1 0 2 2 2 0 Thrombospondin type 1 domain SEFIR PF08357.11 CBY20314.1 - 0.094 13.0 0.1 0.13 12.5 0.1 1.3 1 1 0 1 1 1 0 SEFIR domain Vps39_1 PF10366.9 CBY20315.1 - 0.25 11.6 1.7 0.39 11.0 0.1 2.1 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 PX PF00787.24 CBY20316.1 - 1.2e-25 89.7 0.2 1.4e-25 89.5 0.2 1.1 1 0 0 1 1 1 1 PX domain ZT_dimer PF16916.5 CBY20316.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter GSH_synth_ATP PF03917.17 CBY20317.1 - 3.2e-34 118.3 0.0 3.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CBY20317.1 - 4.2e-07 30.3 0.1 9.4e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Med31 PF05669.12 CBY20317.1 - 0.041 13.9 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 SOH1 GSH_synth_ATP PF03917.17 CBY20318.1 - 4.8e-31 107.9 0.2 5.4e-31 107.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CBY20318.1 - 1.7e-08 34.9 0.4 4.2e-08 33.6 0.4 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Phospholip_B PF04916.13 CBY20318.1 - 0.025 13.2 0.1 0.042 12.4 0.1 1.2 1 0 0 1 1 1 0 Phospholipase B DUF3829 PF12889.7 CBY20318.1 - 0.059 12.9 3.5 0.72 9.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Nuf2 PF03800.14 CBY20319.1 - 3e-09 37.1 0.8 3e-09 37.1 0.8 2.6 3 2 0 3 3 3 1 Nuf2 family APG6_N PF17675.1 CBY20319.1 - 0.0012 19.4 15.2 0.0012 19.4 15.2 3.8 1 1 2 3 3 3 1 Apg6 coiled-coil region HYLS1_C PF15311.6 CBY20319.1 - 1.4 9.7 11.5 2.8 8.8 3.0 2.7 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus DUF1664 PF07889.12 CBY20319.1 - 5 7.2 26.6 2.8 8.0 9.5 3.4 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) Spore_SspJ PF09575.10 CBY20319.1 - 5.5 7.4 7.7 44 4.6 0.1 3.6 3 0 0 3 3 3 0 Small spore protein J (Spore_SspJ) KxDL PF10241.9 CBY20319.1 - 8 6.8 25.0 0.41 10.9 2.6 4.2 2 2 1 3 3 3 0 Uncharacterized conserved protein Rrp15p PF07890.12 CBY20320.1 - 4.1e-18 66.0 8.1 5.6e-18 65.6 8.1 1.3 1 0 0 1 1 1 1 Rrp15p TMPIT PF07851.13 CBY20321.1 - 9.9e-80 268.2 2.7 1.2e-79 267.9 2.7 1.0 1 0 0 1 1 1 1 TMPIT-like protein BicD PF09730.9 CBY20321.1 - 0.0096 14.4 1.2 0.013 14.0 1.2 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Kelch_3 PF13415.6 CBY20322.1 - 3.9e-22 78.0 8.0 5.9e-11 42.4 0.0 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY20322.1 - 7.9e-18 64.2 9.5 3e-05 23.9 0.0 6.3 5 2 1 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY20322.1 - 1.6e-16 59.9 7.4 0.00012 22.2 0.2 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 CBY20322.1 - 3.1e-15 55.8 0.2 1.3e-07 31.5 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CBY20322.1 - 9.8e-14 50.7 14.1 6.9e-07 28.8 0.1 6.3 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CBY20322.1 - 3e-11 42.8 5.2 2.2e-05 24.3 0.2 5.8 6 0 0 6 6 6 2 Kelch motif Muskelin_N PF06588.11 CBY20322.1 - 9.4e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Muskelin N-terminus DUF4580 PF15162.6 CBY20322.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) SURF6 PF04935.12 CBY20323.1 - 3.5e-33 115.1 58.2 6e-33 114.3 58.2 1.4 1 0 0 1 1 1 1 Surfeit locus protein 6 RRP14 PF15459.6 CBY20323.1 - 0.0091 16.6 0.0 0.0091 16.6 0.0 5.8 3 2 1 4 4 4 1 60S ribosome biogenesis protein Rrp14 STT3 PF02516.14 CBY20324.1 - 2.5e-08 33.3 1.5 2.9e-08 33.1 1.5 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Phage_holin_8 PF16931.5 CBY20324.1 - 0.09 12.8 0.9 0.17 11.9 0.9 1.5 1 0 0 1 1 1 0 Putative phage holin VIT1 PF01988.19 CBY20324.1 - 0.44 10.4 4.3 0.36 10.7 2.9 1.5 1 1 0 1 1 1 0 VIT family Comm PF15957.5 CBY20328.1 - 0.26 11.6 1.3 0.45 10.9 1.3 1.3 1 0 0 1 1 1 0 Commissureless FAM176 PF14851.6 CBY20328.1 - 0.33 10.6 2.0 0.23 11.1 0.7 1.5 2 0 0 2 2 2 0 FAM176 family DUF2207 PF09972.9 CBY20329.1 - 0.032 13.0 0.1 0.032 13.0 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MukB_hinge PF16330.5 CBY20329.1 - 0.04 13.6 1.3 0.081 12.6 1.3 1.4 1 0 0 1 1 1 0 MukB hinge domain Na_trans_assoc PF06512.13 CBY20329.1 - 0.059 13.7 0.2 0.093 13.0 0.2 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Mtp PF03821.16 CBY20329.1 - 0.061 12.9 2.9 1.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter DUF2080 PF09853.9 CBY20329.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) Pep1_7 PF17232.2 CBY20329.1 - 0.92 10.0 4.3 2.3 8.7 4.3 1.7 1 0 0 1 1 1 0 Elicitor peptide 1-7 DUF2013 PF09431.10 CBY20330.1 - 9.2e-28 97.1 3.3 2.2e-27 95.9 3.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) SH3_1 PF00018.28 CBY20330.1 - 2.5e-08 33.4 0.0 4.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY20330.1 - 2.7e-07 30.3 0.1 5.7e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY20330.1 - 4.8e-05 22.9 0.0 9.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MMS22L_C PF14911.6 CBY20330.1 - 0.0079 15.3 1.0 0.015 14.4 1.0 1.4 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal TIP120 PF08623.10 CBY20330.1 - 0.008 16.0 1.7 0.03 14.1 0.1 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Adaptin_binding PF10199.9 CBY20330.1 - 0.021 15.4 0.0 0.15 12.7 0.0 2.3 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 hSH3 PF14603.6 CBY20330.1 - 0.11 13.0 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Helically-extended SH3 domain SH3_3 PF08239.11 CBY20330.1 - 0.16 12.2 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Neprosin PF03080.15 CBY20330.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Neprosin zf-AD PF07776.15 CBY20330.1 - 0.31 11.3 1.7 1.4 9.2 1.6 2.3 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Homeodomain PF00046.29 CBY20331.1 - 3.2e-20 71.7 1.6 7.7e-20 70.5 1.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY20331.1 - 0.016 15.1 0.3 0.035 14.0 0.3 1.5 1 0 0 1 1 1 0 Homeobox KN domain Ifi-6-16 PF06140.13 CBY20332.1 - 3.8e-06 26.7 1.1 6e-06 26.1 1.1 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family Glyco_transf_10 PF00852.19 CBY20333.1 - 2.1e-44 151.3 2.7 4e-44 150.4 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY20333.1 - 1.3e-15 57.8 0.3 4.7e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal FAM176 PF14851.6 CBY20333.1 - 0.00021 21.0 3.1 0.00051 19.7 3.1 1.6 1 0 0 1 1 1 1 FAM176 family Leader_CPA1 PF08252.11 CBY20333.1 - 0.11 11.9 0.1 0.29 10.5 0.1 1.7 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide DUF1515 PF07439.11 CBY20333.1 - 0.21 11.6 2.5 1.6 8.8 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Nucleoside_tran PF01733.18 CBY20333.1 - 0.28 10.5 2.5 0.22 10.9 0.7 1.5 1 1 1 2 2 2 0 Nucleoside transporter AAA_11 PF13086.6 CBY20333.1 - 0.67 9.7 9.1 1.5 8.5 9.1 1.5 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 CBY20333.1 - 4.4 6.4 5.6 6.2 5.9 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FGF PF00167.18 CBY20334.1 - 7.6e-25 87.4 0.0 1e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor TFIIE_alpha PF02002.17 CBY20335.1 - 0.0062 16.4 3.5 1.4 8.8 0.9 2.7 2 0 0 2 2 2 2 TFIIE alpha subunit Sipho_Gp157 PF05565.11 CBY20335.1 - 0.016 15.3 0.2 0.016 15.3 0.2 2.6 2 0 0 2 2 2 0 Siphovirus Gp157 Anticodon_1 PF08264.13 CBY20335.1 - 0.055 13.4 0.2 0.055 13.4 0.2 3.2 4 0 0 4 4 4 0 Anticodon-binding domain of tRNA Elf4 PF07011.11 CBY20335.1 - 0.35 10.8 5.1 19 5.3 0.1 4.0 3 1 1 4 4 4 0 Early Flowering 4 domain FapA PF03961.13 CBY20335.1 - 8.4 4.9 11.1 1.8 7.1 4.8 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A TPR_1 PF00515.28 CBY20336.1 - 7.1e-18 63.6 4.7 0.00039 20.1 0.0 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 CBY20336.1 - 3.7e-17 61.0 4.7 0.097 12.8 0.1 6.4 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 CBY20336.1 - 4.2e-12 45.6 0.1 0.0094 16.3 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY20336.1 - 4.3e-12 46.2 2.8 0.00028 21.1 0.3 5.3 3 1 2 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY20336.1 - 1.2e-11 44.6 6.9 0.0014 18.8 0.1 4.8 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY20336.1 - 3e-11 43.6 3.1 0.00086 19.8 0.0 5.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY20336.1 - 3.6e-10 39.2 13.2 0.17 12.2 0.1 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBY20336.1 - 1.5e-09 37.2 3.4 0.0081 16.1 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY20336.1 - 2.7e-09 37.5 0.0 0.0041 17.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY20336.1 - 4.9e-08 33.2 0.1 3.5 8.7 0.0 5.4 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY20336.1 - 7.1e-07 28.8 3.1 0.84 9.4 0.0 6.1 5 1 1 6 6 6 2 TPR repeat DUF627 PF04781.12 CBY20336.1 - 0.00051 20.0 0.1 0.016 15.2 0.0 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF627) TPR_10 PF13374.6 CBY20336.1 - 0.0029 17.4 5.5 0.76 9.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY20336.1 - 0.0063 17.1 2.8 23 5.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY20336.1 - 0.012 15.6 4.7 1.1 9.3 0.1 4.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 CBY20336.1 - 0.034 13.9 1.5 0.15 11.7 0.1 2.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF1965 PF09248.10 CBY20336.1 - 0.14 11.9 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) Pkinase PF00069.25 CBY20337.1 - 3.9e-62 210.0 0.0 3.3e-38 131.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20337.1 - 3.9e-40 137.8 0.0 3.3e-27 95.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY20337.1 - 2.2e-05 23.9 0.0 0.0082 15.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FAM91_C PF14648.6 CBY20337.1 - 0.0017 17.2 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 FAM91 C-terminus Kdo PF06293.14 CBY20337.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY20337.1 - 0.015 14.1 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CBY20337.1 - 0.021 14.8 0.0 0.065 13.1 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBY20337.1 - 0.16 11.6 0.1 5.5 6.6 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2046 PF09755.9 CBY20338.1 - 7.8e-133 442.4 55.6 9.9e-133 442.0 55.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) WD40_alt PF14077.6 CBY20338.1 - 0.023 14.5 3.1 1.5 8.7 0.1 3.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF5082 PF16888.5 CBY20338.1 - 2 8.7 37.4 15 5.9 12.1 5.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) FlgN PF05130.12 CBY20338.1 - 3.6 8.1 44.4 1.7 9.2 18.3 2.7 1 1 1 2 2 2 0 FlgN protein CENP-F_leu_zip PF10473.9 CBY20338.1 - 8.6 6.4 64.7 12 5.9 14.0 4.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2046 PF09755.9 CBY20339.1 - 7.3e-135 449.0 52.9 1.1e-134 448.4 52.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Piwi PF02171.17 CBY20339.1 - 1.1e-101 340.1 0.3 2.5e-101 338.9 0.0 1.7 2 0 0 2 2 2 1 Piwi domain WD40_alt PF14077.6 CBY20339.1 - 0.13 12.2 3.3 3.1 7.7 0.2 2.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF5082 PF16888.5 CBY20339.1 - 1.8 8.9 36.4 1.4 9.2 10.2 3.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Piwi PF02171.17 CBY20340.1 - 1.6e-110 369.1 0.0 3e-110 368.2 0.0 1.5 2 0 0 2 2 2 1 Piwi domain ArgoMid PF16487.5 CBY20340.1 - 2.4e-30 104.6 0.2 1e-29 102.6 0.2 2.2 1 0 0 1 1 1 1 Mid domain of argonaute ArgoN PF16486.5 CBY20340.1 - 7.4e-28 97.9 0.0 1.8e-27 96.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 CBY20340.1 - 6.9e-23 81.0 0.1 1.2e-22 80.2 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CBY20340.1 - 4e-22 77.6 0.2 8.9e-22 76.5 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CBY20340.1 - 5e-17 62.0 0.1 1.1e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain Piwi PF02171.17 CBY20341.1 - 6.8e-116 386.7 0.1 9.7e-116 386.2 0.1 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CBY20341.1 - 5.6e-31 108.0 0.0 1.2e-30 106.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 CBY20341.1 - 2.6e-24 85.6 0.1 5.1e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CBY20341.1 - 5.1e-23 80.5 0.1 1.1e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CBY20341.1 - 3.4e-08 33.7 0.1 8.6e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 CBY20341.1 - 7.2e-08 32.6 0.2 3.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Mid domain of argonaute Sybindin PF04099.12 CBY20342.1 - 9.4e-32 109.9 0.2 1.1e-31 109.7 0.2 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CBY20342.1 - 0.056 13.6 0.0 0.073 13.2 0.0 1.3 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region NARP1 PF12569.8 CBY20343.1 - 1.3e-148 496.2 27.8 5.2e-147 490.9 20.9 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CBY20343.1 - 1.1e-14 53.3 19.5 0.0047 16.9 0.1 9.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBY20343.1 - 2.1e-10 39.9 22.3 0.023 14.9 0.1 10.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY20343.1 - 7.4e-10 38.2 16.6 0.038 13.8 0.3 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY20343.1 - 6.2e-08 32.8 13.0 1.9 8.9 0.0 7.9 6 2 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY20343.1 - 1e-07 32.1 18.2 0.025 14.8 0.7 5.7 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY20343.1 - 8.8e-07 29.3 9.2 0.0098 16.4 0.2 5.9 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY20343.1 - 1.8e-06 28.3 3.2 24 6.1 0.0 8.5 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY20343.1 - 4e-06 27.4 0.9 3.2 8.5 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBY20343.1 - 0.00082 18.7 5.1 0.025 13.8 0.8 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY20343.1 - 0.0038 16.9 11.8 0.0053 16.4 0.2 4.4 5 0 0 5 5 5 1 TPR repeat TPR_4 PF07721.14 CBY20343.1 - 0.0057 17.2 0.7 52 4.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 CBY20343.1 - 0.0096 16.0 0.9 0.053 13.6 0.1 2.7 2 1 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_17 PF13431.6 CBY20343.1 - 0.028 14.8 2.5 2.6 8.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY20343.1 - 0.073 13.2 3.4 0.17 12.0 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Pullulanase_Ins PF18494.1 CBY20343.1 - 0.14 12.6 0.1 0.91 10.0 0.0 2.5 2 0 0 2 2 1 0 Pullulanase Ins domain U79_P34 PF03064.16 CBY20343.1 - 0.56 9.5 9.3 1.3 8.3 9.3 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Fis1_TPR_C PF14853.6 CBY20343.1 - 1.1 9.3 6.6 1.8 8.7 0.0 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF4298 PF14131.6 CBY20343.1 - 1.5 8.8 6.4 2.3 8.3 1.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) TPR_10 PF13374.6 CBY20343.1 - 1.7 8.6 9.4 1.8 8.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY20343.1 - 1.9 9.3 11.0 89 4.1 0.1 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF4288 PF14119.6 CBY20343.1 - 3.8 8.0 7.4 0.54 10.7 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Pkinase PF00069.25 CBY20344.1 - 1.6e-14 53.9 0.0 3.4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20344.1 - 1.1e-12 47.8 0.0 2.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CBY20344.1 - 0.00025 21.2 0.1 0.00073 19.7 0.1 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pyr_redox_2 PF07992.14 CBY20345.1 - 4.2e-43 147.7 0.1 8.5e-43 146.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 CBY20345.1 - 8.9e-37 126.4 2.1 2.5e-21 76.4 0.1 2.7 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 CBY20345.1 - 3e-10 40.5 0.2 8.6e-09 35.8 0.5 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBY20345.1 - 3.8e-08 32.9 0.4 1.3e-07 31.2 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBY20345.1 - 2.1e-06 27.8 0.0 0.0014 18.7 0.0 3.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 CBY20345.1 - 3e-05 23.5 0.1 5.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 CBY20345.1 - 0.00082 18.6 0.0 0.025 13.7 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CBY20345.1 - 0.0033 17.1 1.3 0.037 13.6 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CBY20345.1 - 0.017 15.6 0.3 0.38 11.2 0.0 3.0 3 1 1 4 4 4 0 Putative NAD(P)-binding Reductase_C PF14759.6 CBY20345.1 - 0.023 15.2 0.1 0.19 12.3 0.1 2.7 2 1 0 2 2 1 0 Reductase C-terminal HI0933_like PF03486.14 CBY20345.1 - 0.055 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein DUF4710 PF15828.5 CBY20346.1 - 0.002 18.2 1.0 0.0065 16.6 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4710) Chalcone_3 PF16036.5 CBY20346.1 - 0.005 17.0 0.0 0.0083 16.3 0.0 1.5 1 0 0 1 1 1 1 Chalcone isomerase-like Phospholip_A2_1 PF00068.19 CBY20347.1 - 1.4e-15 57.7 4.4 2.8e-15 56.7 4.4 1.5 1 0 0 1 1 1 1 Phospholipase A2 RFX_DNA_binding PF02257.15 CBY20348.1 - 0.019 15.6 0.1 0.035 14.7 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain LpxK PF02606.14 CBY20348.1 - 0.021 14.0 0.1 0.031 13.4 0.1 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Presenilin PF01080.17 CBY20352.1 - 0.89 8.2 5.6 1.3 7.7 5.6 1.2 1 0 0 1 1 1 0 Presenilin bZIP_1 PF00170.21 CBY20353.1 - 3.6e-06 27.0 12.5 9.8e-06 25.6 12.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY20353.1 - 4.4e-05 23.5 16.1 4.4e-05 23.5 16.1 2.1 2 1 0 2 2 2 1 Basic region leucine zipper LCD1 PF09798.9 CBY20353.1 - 0.0042 15.7 0.2 0.0058 15.2 0.2 1.2 1 0 0 1 1 1 1 DNA damage checkpoint protein HOOK PF05622.12 CBY20353.1 - 0.0071 14.6 0.3 0.011 13.9 0.3 1.2 1 0 0 1 1 1 1 HOOK protein YabA PF06156.13 CBY20353.1 - 1.3 9.7 8.2 0.75 10.5 1.9 2.4 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_Maf PF03131.17 CBY20353.1 - 3.9 8.1 14.0 0.12 13.0 7.3 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Pox_G5 PF04599.12 CBY20353.1 - 6.1 5.7 4.7 8.5 5.3 4.7 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Zona_pellucida PF00100.23 CBY20354.1 - 1.3e-43 149.7 5.9 1.7e-43 149.3 5.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.27 CBY20354.1 - 5.7e-06 26.5 6.2 1.6e-05 25.1 6.2 1.8 1 0 0 1 1 1 1 EGF-like domain CcmD PF04995.14 CBY20354.1 - 0.016 15.3 0.2 0.027 14.5 0.2 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Mito_carr PF00153.27 CBY20355.1 - 4.4e-54 180.4 0.3 1.5e-23 82.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA_Me_trans PF03054.16 CBY20356.1 - 0.00066 18.6 0.0 0.00089 18.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase tRNA_Me_trans PF03054.16 CBY20357.1 - 1.1e-59 202.0 0.2 2.1e-59 201.1 0.2 1.4 1 1 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 CBY20357.1 - 8.1e-05 22.4 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 CBY20357.1 - 0.0015 18.2 0.0 0.048 13.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 CBY20357.1 - 0.0018 17.8 0.0 0.09 12.3 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 CBY20357.1 - 0.0032 16.6 0.0 0.0072 15.5 0.0 1.6 2 0 0 2 2 2 1 NAD synthase ATP_bind_3 PF01171.20 CBY20357.1 - 0.52 10.0 4.4 0.77 9.5 1.0 2.8 2 1 0 2 2 2 0 PP-loop family GNAT_acetyltr_2 PF13718.6 CBY20358.1 - 4.3e-161 533.3 0.3 4.7e-85 284.6 0.0 2.8 3 0 0 3 3 3 2 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 CBY20358.1 - 7.8e-123 406.9 0.0 7.5e-60 201.8 0.0 3.0 3 0 0 3 3 3 2 Helicase tRNA_bind_2 PF13725.6 CBY20358.1 - 1.9e-47 162.0 3.3 3.4e-47 161.1 3.3 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 CBY20358.1 - 3e-32 110.4 0.1 9.1e-32 108.9 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.7 CBY20358.1 - 5.5e-07 29.9 0.0 0.09 13.2 0.0 2.9 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY20358.1 - 1.6e-05 25.1 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY20358.1 - 0.0018 18.2 0.1 5.3 7.0 0.0 3.2 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain PL48 PF15903.5 CBY20358.1 - 0.0031 16.5 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 2 Filopodia upregulated, FAM65 Acetyltransf_3 PF13302.7 CBY20358.1 - 0.0033 18.1 0.0 6.6 7.4 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY20358.1 - 0.0063 16.5 0.1 8.9 6.4 0.0 3.1 2 0 0 2 2 2 2 FR47-like protein DUF3618 PF12277.8 CBY20358.1 - 0.099 12.9 0.1 8.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Y1_Tnp PF01797.16 CBY20358.1 - 1 9.5 3.5 35 4.5 0.1 2.9 3 0 0 3 3 3 0 Transposase IS200 like SAM_Exu PF18609.1 CBY20358.1 - 1.4 9.1 3.7 35 4.6 0.0 2.7 2 0 0 2 2 2 0 Exuperantia SAM-like domain LPMO_10 PF03067.15 CBY20360.1 - 1.3e-34 120.6 0.3 1.3e-34 120.6 0.3 1.9 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY20360.1 - 9.8e-13 48.1 6.7 4e-12 46.1 6.7 2.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain FSA_C PF10479.9 CBY20360.1 - 1.7 6.7 13.0 2.2 6.3 13.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LPMO_10 PF03067.15 CBY20361.1 - 4.5e-32 112.3 1.1 4.5e-32 112.3 1.1 1.7 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY20361.1 - 5.4e-12 45.7 6.7 1.8e-11 44.0 6.7 2.0 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Mucin PF01456.17 CBY20361.1 - 0.25 11.3 13.6 0.4 10.7 13.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ank_2 PF12796.7 CBY20365.1 - 4e-06 27.3 0.0 0.08 13.5 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY20365.1 - 2.7e-05 24.6 0.0 0.0021 18.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY20365.1 - 0.0019 18.6 0.0 1.8 9.4 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat UBX PF00789.20 CBY20365.1 - 0.081 13.1 0.1 0.33 11.2 0.1 2.1 1 0 0 1 1 1 0 UBX domain DUF1690 PF07956.11 CBY20365.1 - 0.22 12.0 3.3 0.46 10.9 3.2 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Adaptin_N PF01602.20 CBY20366.1 - 2.4e-111 372.9 11.6 2.4e-111 372.9 11.6 1.6 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 CBY20366.1 - 9.4e-16 58.3 4.9 3.1e-11 43.6 0.0 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 AP3D1 PF06375.11 CBY20366.1 - 4.3e-07 30.3 8.7 1.5e-06 28.6 8.7 1.9 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 HEAT PF02985.22 CBY20366.1 - 1.2e-05 25.2 2.4 0.24 11.8 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat RTP1_C1 PF10363.9 CBY20366.1 - 0.00045 20.4 3.4 1.3 9.3 0.6 3.6 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 CBY20366.1 - 0.00049 20.4 0.6 2.6 8.5 0.0 3.6 2 1 1 3 3 3 3 HEAT repeats AP4E_app_platf PF14807.6 CBY20366.1 - 0.002 18.4 0.5 0.0059 16.9 0.5 1.8 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform V-ATPase_H_C PF11698.8 CBY20366.1 - 0.041 14.0 0.7 1.1 9.4 0.3 3.6 3 1 0 3 3 3 0 V-ATPase subunit H M11L PF11099.8 CBY20366.1 - 0.66 10.2 7.6 1.6 9.0 2.9 3.1 2 1 1 3 3 3 0 Apoptosis regulator M11L like YHYH PF14240.6 CBY20369.1 - 4e-21 75.9 2.4 7.3e-14 52.2 0.1 2.6 2 1 1 3 3 3 2 YHYH protein Anti-TRAP PF15777.5 CBY20369.1 - 0.07 13.1 0.1 0.23 11.5 0.1 1.9 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein TPR_12 PF13424.6 CBY20370.1 - 5.3e-11 42.6 10.3 3.9e-06 27.1 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY20370.1 - 5.9e-06 25.9 3.5 0.00034 20.1 1.1 2.4 2 0 0 2 2 2 2 MalT-like TPR region zf-RING_11 PF17123.5 CBY20370.1 - 0.00065 19.4 1.4 0.0015 18.2 1.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger Rapsyn_N PF10579.9 CBY20370.1 - 0.0033 17.5 0.2 0.014 15.5 0.1 2.1 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region SNAP PF14938.6 CBY20370.1 - 0.0073 15.8 6.5 0.0073 15.8 6.5 2.0 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP zf-RING_2 PF13639.6 CBY20370.1 - 0.011 16.1 7.0 0.032 14.6 7.0 1.9 1 0 0 1 1 1 0 Ring finger domain TPR_19 PF14559.6 CBY20370.1 - 0.034 14.7 5.4 0.42 11.2 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CBY20370.1 - 0.038 14.0 5.9 0.81 9.8 1.2 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 CBY20370.1 - 0.039 14.6 0.1 8.9 7.3 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY20370.1 - 0.12 13.0 3.0 2.3 8.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 CBY20370.1 - 0.13 12.2 3.4 0.46 10.4 3.4 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY20370.1 - 0.23 11.4 8.5 0.62 10.1 8.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain TPR_10 PF13374.6 CBY20370.1 - 0.27 11.2 4.6 11 6.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY20370.1 - 0.28 11.5 10.8 55 4.3 0.1 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY20370.1 - 1 9.6 6.5 8.1 6.7 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Phospholip_A2_1 PF00068.19 CBY20371.1 - 2.9e-07 30.9 3.4 4.3e-07 30.4 3.4 1.4 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY20372.1 - 3.1e-05 24.4 0.5 3.1e-05 24.4 0.5 2.1 2 1 0 2 2 2 1 Phospholipase A2 Sec10 PF07393.11 CBY20373.1 - 2.1e-119 400.0 17.3 2.5e-71 241.1 2.1 3.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 HHH_6 PF14579.6 CBY20373.1 - 0.071 13.4 0.2 0.22 11.8 0.2 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF1043 PF06295.12 CBY20373.1 - 0.43 10.6 5.1 0.28 11.2 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 CBY20373.1 - 1.5 8.9 8.5 2.8 8.0 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 CBY20373.1 - 3.3 8.1 8.5 0.82 10.1 3.0 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) FAM183 PF14886.6 CBY20374.1 - 1.5e-31 109.3 0.3 1.8e-31 109.1 0.3 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related LLC1 PF14945.6 CBY20374.1 - 6.2e-06 26.8 0.3 1.1e-05 26.0 0.3 1.3 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Peptidase_M16_C PF05193.21 CBY20375.1 - 1.1e-07 32.0 0.0 1.1e-06 28.8 0.0 2.5 2 1 0 2 2 2 1 Peptidase M16 inactive domain Talin_middle PF09141.10 CBY20375.1 - 0.039 14.0 0.2 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 Talin, middle domain YopE_N PF09020.10 CBY20376.1 - 0.034 14.4 0.4 0.04 14.2 0.4 1.3 1 1 0 1 1 1 0 YopE, N terminal DUF4038 PF13204.6 CBY20376.1 - 0.079 12.6 0.0 0.091 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Actin PF00022.19 CBY20377.1 - 2.2e-152 507.4 0.0 7.1e-152 505.7 0.0 1.6 1 1 0 1 1 1 1 Actin DUF3574 PF12098.8 CBY20378.1 - 0.12 12.2 0.3 0.18 11.6 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3574) Arm PF00514.23 CBY20379.1 - 7.8e-19 67.0 0.3 0.00018 21.5 0.0 6.4 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 CBY20379.1 - 3.8e-05 22.9 4.2 0.11 11.5 0.0 2.7 1 1 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term Atx10homo_assoc PF09759.9 CBY20379.1 - 3.9e-05 23.6 0.2 0.016 15.3 0.2 3.4 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 CBY20379.1 - 0.0063 16.7 0.3 68 4.1 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat UME PF08064.13 CBY20379.1 - 0.019 14.9 0.1 0.4 10.6 0.0 3.0 2 0 0 2 2 2 0 UME (NUC010) domain V-ATPase_H_N PF03224.14 CBY20379.1 - 0.034 13.5 0.2 0.23 10.7 0.0 2.2 1 1 0 2 2 2 0 V-ATPase subunit H GDC-P PF02347.16 CBY20380.1 - 3.4e-179 596.2 0.0 7.1e-167 555.6 0.2 2.1 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CBY20380.1 - 3.8e-07 29.4 0.9 6.2e-05 22.1 0.0 2.7 3 0 0 3 3 3 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBY20380.1 - 0.0006 19.2 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Cadherin PF00028.17 CBY20381.1 - 3.5e-79 261.3 4.9 1.4e-15 57.5 0.0 7.2 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CBY20381.1 - 5.4e-12 45.4 0.2 2.6e-05 23.9 0.0 5.5 7 0 0 7 7 7 2 Cadherin-like Cadherin_3 PF16184.5 CBY20381.1 - 3e-05 24.0 9.0 0.56 10.2 0.0 5.6 5 1 1 6 6 6 2 Cadherin-like Cadherin_pro PF08758.11 CBY20381.1 - 4.2e-05 23.6 0.0 0.0003 20.9 0.0 2.5 2 0 0 2 2 2 1 Cadherin prodomain like Cadherin_4 PF17803.1 CBY20381.1 - 0.00023 21.7 19.2 0.24 12.0 0.7 6.1 6 0 0 6 6 6 2 Bacterial cadherin-like domain Orf78 PF06024.12 CBY20381.1 - 0.011 16.1 0.1 0.031 14.6 0.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF4212 PF13937.6 CBY20381.1 - 0.1 13.0 0.2 0.2 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) EphA2_TM PF14575.6 CBY20381.1 - 0.12 13.3 0.0 0.27 12.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 CBY20381.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1180 PF06679.12 CBY20381.1 - 5 7.5 9.0 0.49 10.8 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Galactosyl_T PF01762.21 CBY20382.1 - 0.0013 18.5 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase G10 PF01125.17 CBY20384.1 - 8.8e-67 223.4 8.3 9.7e-67 223.3 8.3 1.0 1 0 0 1 1 1 1 G10 protein LRR_8 PF13855.6 CBY20385.1 - 3.3e-18 65.2 11.9 2.2e-10 40.1 3.5 4.5 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CBY20385.1 - 4.1e-16 58.8 25.4 4.1e-07 30.2 0.3 5.6 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY20385.1 - 0.0017 17.9 6.8 0.066 12.7 0.4 3.7 1 1 3 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 CBY20385.1 - 0.079 13.5 19.9 17 6.4 0.1 6.7 7 1 0 7 7 7 0 Leucine Rich Repeat UPF0029 PF01205.19 CBY20386.1 - 1.1e-25 90.0 0.0 1.7e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 TF_AP-2 PF03299.14 CBY20387.1 - 0.073 13.0 2.5 2.2 8.2 1.2 2.2 2 0 0 2 2 2 0 Transcription factor AP-2 zf-AN1 PF01428.16 CBY20387.1 - 0.4 10.9 2.9 0.89 9.8 2.9 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger ASC PF00858.24 CBY20389.1 - 3.3e-54 184.6 13.8 4e-54 184.2 13.8 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TPT PF03151.16 CBY20390.1 - 1.5e-24 86.9 19.7 1.8e-24 86.6 19.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY20390.1 - 1.7e-10 41.2 7.4 1.7e-10 41.2 7.4 2.2 2 0 0 2 2 2 1 EamA-like transporter family Multi_Drug_Res PF00893.19 CBY20390.1 - 2.3 8.9 10.7 0.2 12.4 0.5 3.2 1 1 1 3 3 3 0 Small Multidrug Resistance protein DUF1674 PF07896.12 CBY20391.1 - 0.98 9.9 3.0 0.79 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1674) Claudin_2 PF13903.6 CBY20392.1 - 5.1e-05 23.1 9.1 0.00014 21.7 9.1 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CBY20392.1 - 0.013 15.3 4.8 0.04 13.8 4.8 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family zf-C4 PF00105.18 CBY20393.1 - 4.1e-07 30.4 13.8 8.6e-07 29.3 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF4116 PF13475.6 CBY20393.1 - 0.067 12.9 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Zn_protease PF05618.11 CBY20393.1 - 0.076 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease Ig_3 PF13927.6 CBY20394.1 - 1.7e-20 73.4 1.8 2.2e-06 28.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CBY20394.1 - 1.9e-14 53.5 1.1 0.00068 19.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 CBY20394.1 - 2.3e-14 53.3 2.6 0.00014 22.0 0.2 3.4 3 1 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY20394.1 - 3.4e-12 46.3 0.9 1.4e-09 37.8 0.0 3.0 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 CBY20394.1 - 1.5e-11 44.5 3.2 0.019 15.3 0.2 3.6 1 1 1 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CBY20394.1 - 4.3e-08 33.3 1.5 1.7e-06 28.1 0.2 3.0 3 0 0 3 3 3 1 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.15 CBY20394.1 - 0.015 15.1 0.7 0.047 13.5 0.0 2.1 2 1 1 3 3 3 0 Adenovirus E3 region protein CR1 Protocadherin PF08374.11 CBY20394.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 CBY20394.1 - 0.041 13.8 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family CRPA PF05745.11 CBY20394.1 - 0.043 13.8 0.1 0.079 13.0 0.1 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tropomyosin PF00261.20 CBY20395.1 - 1e-49 169.1 61.7 7.6e-45 153.1 46.6 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 CBY20395.1 - 6.2e-15 55.6 57.5 6.5e-14 52.3 31.8 2.9 1 1 1 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 CBY20395.1 - 3.1e-08 33.7 29.8 0.0033 17.4 9.3 3.2 1 1 2 3 3 3 3 Laminin Domain II DUF4315 PF14193.6 CBY20395.1 - 0.011 15.7 3.2 0.011 15.7 3.2 5.2 3 3 1 4 4 4 0 Domain of unknown function (DUF4315) DUF1664 PF07889.12 CBY20395.1 - 0.027 14.5 30.8 0.06 13.4 1.9 4.4 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 CBY20395.1 - 0.12 12.6 16.3 1.6 9.0 1.3 4.6 3 2 0 3 3 3 0 Proteins of 100 residues with WXG DAPDH_C PF16654.5 CBY20395.1 - 0.19 11.6 6.1 0.058 13.3 1.1 2.2 2 0 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain ERM PF00769.19 CBY20395.1 - 0.68 9.7 60.7 5.8 6.7 43.0 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family PspA_IM30 PF04012.12 CBY20395.1 - 1.4 8.5 47.4 0.014 14.9 16.0 3.2 1 1 2 3 3 2 0 PspA/IM30 family Synaptobrevin PF00957.21 CBY20395.1 - 2.9 7.7 27.8 0.83 9.5 2.6 4.7 2 2 2 4 4 4 0 Synaptobrevin DUF3450 PF11932.8 CBY20395.1 - 3.9 6.7 39.1 0.1 11.9 4.2 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 CBY20395.1 - 4 6.2 51.4 0.51 9.2 11.8 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein FPP PF05911.11 CBY20395.1 - 7.7 4.6 47.4 12 3.9 29.7 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil VWA PF00092.28 CBY20397.1 - 5e-07 30.1 0.0 7.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Lectin_C PF00059.21 CBY20397.1 - 0.0069 17.1 1.9 0.024 15.4 0.1 2.1 2 0 0 2 2 2 1 Lectin C-type domain Cytochrom_B561 PF03188.16 CBY20398.1 - 3.9e-19 69.1 9.5 2.1e-18 66.8 7.7 2.2 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 DUF4079 PF13301.6 CBY20398.1 - 1.4e-05 25.3 3.4 0.0014 18.8 0.1 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 CBY20398.1 - 0.00018 21.2 11.0 0.018 14.6 7.8 2.6 1 1 0 1 1 1 1 Prokaryotic cytochrome b561 DUF5310 PF17237.2 CBY20398.1 - 0.019 14.8 0.6 0.048 13.5 0.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5310) Sigma_reg_N PF13800.6 CBY20398.1 - 0.058 13.7 0.8 1.6 9.1 0.1 2.7 1 1 1 2 2 2 0 Sigma factor regulator N-terminal SPC25 PF06703.11 CBY20398.1 - 0.24 11.2 1.7 3.5 7.4 0.2 2.6 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4401 PF14351.6 CBY20398.1 - 0.41 9.9 15.8 0.53 9.5 5.2 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4401) Vps55 PF04133.14 CBY20398.1 - 8.3 6.4 9.2 0.4 10.6 1.0 2.7 2 2 0 2 2 2 0 Vacuolar protein sorting 55 zf-3CxxC PF13695.6 CBY20399.1 - 0.08 13.4 1.4 1.6 9.3 0.7 2.5 2 1 0 2 2 2 0 Zinc-binding domain DUF629 PF04780.12 CBY20399.1 - 0.26 9.8 2.7 0.41 9.1 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-Sec23_Sec24 PF04810.15 CBY20399.1 - 0.27 11.3 2.8 4.9 7.3 0.4 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger HSF_DNA-bind PF00447.17 CBY20400.1 - 2.8e-05 24.6 0.1 4.5e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding CK_II_beta PF01214.18 CBY20402.1 - 6.2e-58 195.6 0.0 7.5e-58 195.3 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Lectin_C PF00059.21 CBY20403.1 - 1e-45 154.9 27.2 1e-19 71.2 0.4 5.4 5 1 0 5 5 5 4 Lectin C-type domain UL45 PF05473.12 CBY20403.1 - 6.8e-12 45.4 6.1 9.2e-06 25.4 0.0 4.3 3 1 0 3 3 3 2 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 CBY20403.1 - 0.099 11.9 0.6 0.43 9.8 0.2 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Yuri_gagarin PF15934.5 CBY20404.1 - 0.0036 17.2 0.5 0.0037 17.1 0.5 1.1 1 0 0 1 1 1 1 Yuri gagarin APG17 PF04108.12 CBY20404.1 - 0.0066 15.6 0.8 0.0079 15.4 0.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 B PF02216.16 CBY20404.1 - 0.041 13.9 1.6 0.065 13.2 1.3 1.5 1 1 0 1 1 1 0 B domain DUF1640 PF07798.11 CBY20404.1 - 0.058 13.5 3.9 0.076 13.1 3.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF573 PF04504.14 CBY20404.1 - 0.06 14.0 0.9 0.12 13.1 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF573 N1221 PF07923.13 CBY20404.1 - 0.063 12.5 0.9 0.11 11.7 0.7 1.5 1 1 1 2 2 2 0 N1221-like protein Ribosomal_L10 PF00466.20 CBY20404.1 - 0.14 12.3 1.7 0.17 12.0 0.9 1.8 1 1 1 2 2 2 0 Ribosomal protein L10 zf-CCHC_4 PF14392.6 CBY20404.1 - 0.19 11.5 0.1 0.34 10.7 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4404 PF14357.6 CBY20404.1 - 0.39 11.4 4.0 6.8 7.4 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) CHD5 PF04420.14 CBY20404.1 - 0.88 9.4 3.4 1.4 8.8 3.4 1.5 1 1 0 1 1 1 0 CHD5-like protein Glyco_hydro_125 PF06824.11 CBY20405.1 - 0.045 12.6 0.1 0.34 9.7 0.0 2.1 2 0 0 2 2 2 0 Metal-independent alpha-mannosidase (GH125) ICE2 PF08426.10 CBY20406.1 - 0.016 14.3 0.7 0.027 13.6 0.7 1.2 1 0 0 1 1 1 0 ICE2 PP1_bind PF15276.6 CBY20407.1 - 3.2e-23 81.8 2.2 3.2e-23 81.8 2.2 7.3 7 0 0 7 7 7 1 Protein phosphatase 1 binding Yop-YscD_cpl PF16697.5 CBY20407.1 - 0.0015 18.8 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-met PF12874.7 CBY20409.1 - 0.032 14.6 12.1 2.8 8.5 0.5 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CBY20409.1 - 0.21 12.1 7.1 1.9 9.0 0.2 3.0 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger RecR PF02132.15 CBY20409.1 - 1.2 8.8 7.8 3.9 7.1 0.4 3.0 3 0 0 3 3 3 0 RecR protein zf-C2H2_4 PF13894.6 CBY20409.1 - 3.2 8.8 30.8 0.99 10.4 1.8 5.7 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY20409.1 - 5.4 7.4 22.7 1.9 8.8 0.6 5.6 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF3450 PF11932.8 CBY20410.1 - 0.0028 17.0 5.7 0.0028 17.0 5.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Cauli_DNA-bind PF03310.13 CBY20410.1 - 0.017 15.2 0.5 1.3 9.1 0.3 2.4 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein TPR_MLP1_2 PF07926.12 CBY20410.1 - 0.14 12.2 18.3 0.16 12.0 2.1 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 CBY20410.1 - 2.1 8.7 12.2 2.4 8.6 1.8 3.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMPIT PF07851.13 CBY20410.1 - 2.6 7.2 4.7 5.3 6.2 4.7 1.5 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 CBY20410.1 - 3.2 8.1 10.2 0.31 11.4 5.1 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Striatin PF08232.12 CBY20410.1 - 3.3 8.3 17.5 0.16 12.6 7.6 2.5 2 1 0 2 2 2 0 Striatin family DUF3552 PF12072.8 CBY20410.1 - 3.9 6.8 19.8 0.046 13.1 12.2 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) DUF724 PF05266.14 CBY20410.1 - 5.2 6.8 11.3 0.85 9.4 6.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.20 CBY20410.1 - 5.3 7.1 15.3 0.98 9.4 9.9 2.4 2 1 0 2 2 2 0 Prefoldin subunit GrpE PF01025.19 CBY20410.1 - 5.7 6.6 11.9 2.2 7.9 0.4 2.8 3 0 0 3 3 3 0 GrpE Peptidase_M16 PF00675.20 CBY20411.1 - 7.7e-33 113.6 0.0 1.4e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PDEase_I PF00233.19 CBY20412.1 - 3.1e-48 164.6 0.5 3.8e-48 164.3 0.5 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase NUDIX PF00293.28 CBY20414.1 - 8.5e-07 29.1 0.7 9.8e-07 28.9 0.7 1.1 1 0 0 1 1 1 1 NUDIX domain EXS PF03124.14 CBY20415.1 - 3.2e-76 256.8 18.3 3.2e-76 256.8 18.3 1.8 2 0 0 2 2 2 1 EXS family SPX PF03105.19 CBY20415.1 - 6.9e-24 85.5 20.0 3.4e-09 37.1 1.2 3.2 1 1 2 3 3 3 3 SPX domain DUF2768 PF10966.8 CBY20415.1 - 0.19 12.2 3.0 0.84 10.1 3.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) DUF5638 PF18688.1 CBY20415.1 - 0.23 11.8 3.4 0.44 10.9 0.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5638) DUF4590 PF15257.6 CBY20416.1 - 2.6e-43 146.6 0.8 5.4e-43 145.5 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) DUF4542 PF15075.6 CBY20416.1 - 0.063 13.7 1.4 0.34 11.3 0.1 3.0 3 2 1 4 4 4 0 Domain of unknown function (DUF4542) DnaJ PF00226.31 CBY20417.1 - 9.4e-23 80.1 3.5 9.4e-23 80.1 3.5 2.0 2 0 0 2 2 2 1 DnaJ domain COX4 PF02936.14 CBY20418.1 - 0.00015 21.8 0.3 0.00058 19.9 0.2 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV RhoGAP PF00620.27 CBY20419.1 - 8.4e-18 64.7 0.1 8.4e-18 64.7 0.1 2.5 2 1 0 2 2 2 1 RhoGAP domain SKICH PF17751.1 CBY20420.1 - 2.5e-12 47.3 0.5 1.1e-11 45.1 0.1 2.2 2 0 0 2 2 2 1 SKICH domain Exo_endo_phos PF03372.23 CBY20420.1 - 1.5e-05 24.6 0.0 2.8e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAD_binding_1 PF00667.20 CBY20421.1 - 4.6e-27 95.0 0.0 6.5e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBY20421.1 - 6.3e-23 81.6 0.0 1.6e-22 80.3 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CBY20421.1 - 1.4e-07 32.2 0.0 5.5e-07 30.2 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 CBY20421.1 - 0.00086 19.0 0.0 0.0025 17.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_5 PF12724.7 CBY20421.1 - 0.052 13.8 0.1 6.1 7.1 0.0 2.4 1 1 1 2 2 2 0 Flavodoxin domain Tfb5 PF06331.12 CBY20422.1 - 1.8e-25 88.7 0.0 1.9e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 MMR_HSR1 PF01926.23 CBY20423.1 - 9.4e-16 57.9 0.0 2.4e-13 50.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY20423.1 - 4.3e-06 26.7 2.7 0.077 12.9 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 CBY20423.1 - 1.1e-05 25.0 0.1 5.7e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 CBY20423.1 - 0.016 14.8 0.0 0.051 13.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 CBY20423.1 - 0.12 11.7 0.7 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family RabGAP-TBC PF00566.18 CBY20424.1 - 1.8e-06 27.8 0.4 0.00052 19.7 0.8 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Rhodanese PF00581.20 CBY20424.1 - 2.8e-05 24.6 0.0 5.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Pribosyltran_N PF13793.6 CBY20425.1 - 1.3e-38 131.5 0.2 1.4e-36 124.9 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBY20425.1 - 2.2e-32 112.5 1.7 1.5e-28 100.1 1.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBY20425.1 - 2e-13 50.2 0.4 4.2e-13 49.1 0.3 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GTP-bdg_N PF13167.6 CBY20425.1 - 0.14 12.9 1.1 11 6.7 0.0 3.3 2 1 0 2 2 2 0 GTP-binding GTPase N-terminal LRR_8 PF13855.6 CBY20426.1 - 7.8e-05 22.4 2.5 0.00018 21.2 2.5 1.6 1 0 0 1 1 1 1 Leucine rich repeat IQ PF00612.27 CBY20426.1 - 0.00076 19.1 0.5 0.0024 17.5 0.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_4 PF12799.7 CBY20426.1 - 0.017 15.5 9.6 0.36 11.3 2.1 2.7 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) NAD_binding_5 PF07994.12 CBY20426.1 - 3.2 7.0 5.4 5.3 6.3 5.4 1.4 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase SUZ PF12752.7 CBY20427.1 - 8.2e-14 52.1 0.7 8.2e-14 52.1 0.7 3.7 2 1 0 2 2 2 1 SUZ domain CENP-F_N PF10481.9 CBY20427.1 - 0.063 12.9 1.8 0.09 12.4 1.8 1.3 1 1 0 1 1 1 0 Cenp-F N-terminal domain Tropomyosin PF00261.20 CBY20428.1 - 7e-38 130.3 48.1 8e-38 130.1 48.1 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 CBY20428.1 - 8.1e-10 39.0 50.6 6.5e-08 32.8 19.6 3.1 1 1 2 3 3 3 2 Tropomyosin like DUF4201 PF13870.6 CBY20428.1 - 0.00013 21.7 39.8 0.00024 20.9 12.7 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF4201) Fez1 PF06818.15 CBY20428.1 - 0.0022 18.5 38.3 0.15 12.5 20.2 2.1 1 1 1 2 2 2 2 Fez1 TMF_TATA_bd PF12325.8 CBY20428.1 - 0.004 17.4 7.0 0.004 17.4 7.0 4.0 1 1 3 4 4 4 2 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 CBY20428.1 - 0.0063 15.8 34.4 0.029 13.7 6.9 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) ZapB PF06005.12 CBY20428.1 - 0.0064 16.9 6.4 0.0064 16.9 6.4 4.3 1 1 3 4 4 4 3 Cell division protein ZapB KLRAQ PF10205.9 CBY20428.1 - 0.0099 16.1 35.5 0.03 14.6 7.1 3.5 1 1 2 3 3 3 2 Predicted coiled-coil domain-containing protein bZIP_1 PF00170.21 CBY20428.1 - 0.0099 16.0 29.9 0.1 12.7 3.5 5.4 3 3 2 5 5 5 3 bZIP transcription factor DUF641 PF04859.12 CBY20428.1 - 0.023 15.0 2.6 0.023 15.0 2.6 3.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) ERM PF00769.19 CBY20428.1 - 0.053 13.3 45.6 0.16 11.8 19.6 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ADIP PF11559.8 CBY20428.1 - 0.055 13.6 42.0 0.33 11.0 11.8 3.8 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CBY20428.1 - 0.11 11.3 42.2 0.49 9.2 7.6 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 CBY20428.1 - 0.12 11.8 43.0 0.091 12.2 13.8 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 GAS PF13851.6 CBY20428.1 - 0.15 11.4 41.7 1.5 8.1 20.4 3.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 CBY20428.1 - 0.19 11.2 42.1 0.047 13.2 12.3 2.3 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Mucin15 PF15672.5 CBY20428.1 - 0.22 11.0 3.7 0.27 10.7 3.7 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 TMF_DNA_bd PF12329.8 CBY20428.1 - 0.51 10.4 42.3 0.7 9.9 5.3 5.2 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding IFT57 PF10498.9 CBY20428.1 - 0.94 8.4 33.7 0.08 11.9 9.8 3.1 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 YabA PF06156.13 CBY20428.1 - 1.1 9.9 32.2 1.2 9.8 3.6 3.4 1 1 2 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 CBY20428.1 - 1.4 9.4 48.1 2.9e+02 2.0 18.4 3.6 1 1 1 2 2 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 CBY20428.1 - 1.7 8.7 22.6 1.2 9.2 1.6 3.4 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 CBY20428.1 - 1.9 8.3 36.6 0.14 12.0 10.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 CBY20428.1 - 3.3 5.5 33.1 0.28 9.1 14.4 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 CBY20428.1 - 4.5 7.3 42.1 3.4 7.7 7.2 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein T3SSipB PF16535.5 CBY20428.1 - 5.3 7.5 22.7 5.8 7.4 4.6 3.1 1 1 2 3 3 3 0 Type III cell invasion protein SipB DHR10 PF18595.1 CBY20428.1 - 5.8 7.0 48.2 2.2 8.4 5.1 3.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain BORCS7 PF16088.5 CBY20428.1 - 7.1 6.9 17.9 0.6 10.4 0.4 3.8 1 1 3 4 4 4 0 BLOC-1-related complex sub-unit 7 DUF3584 PF12128.8 CBY20428.1 - 7.8 3.9 41.4 16 2.8 41.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) RasGAP_C PF03836.15 CBY20428.1 - 8.3 6.6 24.3 0.47 10.6 8.2 3.3 1 1 2 3 3 3 0 RasGAP C-terminus Jnk-SapK_ap_N PF09744.9 CBY20428.1 - 9.7 6.4 46.8 9.5 6.4 19.9 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Pkinase PF00069.25 CBY20429.1 - 9.6e-63 212.0 0.0 9.6e-63 212.0 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20429.1 - 1.4e-35 122.9 0.0 4.7e-35 121.1 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBY20429.1 - 5.2e-08 33.4 2.8 8.4e-07 29.5 0.0 3.9 3 1 0 3 3 3 1 PH domain Rho_Binding PF08912.11 CBY20429.1 - 4.1e-06 27.5 12.7 4.1e-06 27.5 12.7 11.1 3 3 5 10 10 10 1 Rho Binding C1_1 PF00130.22 CBY20429.1 - 0.0045 16.8 2.1 0.0091 15.9 2.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Rootletin PF15035.6 CBY20429.1 - 0.0094 16.0 23.3 0.0094 16.0 23.3 6.1 1 1 3 5 5 5 1 Ciliary rootlet component, centrosome cohesion APH PF01636.23 CBY20429.1 - 0.016 15.2 0.1 0.016 15.2 0.1 2.9 3 1 0 4 4 4 0 Phosphotransferase enzyme family PHD PF00628.29 CBY20429.1 - 0.019 14.8 1.3 0.051 13.5 1.3 1.6 1 0 0 1 1 1 0 PHD-finger RRM_1 PF00076.22 CBY20430.1 - 2.6e-14 52.8 0.1 4.7e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBY20431.1 - 6.9e-13 48.2 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CBY20431.1 - 1.8e-08 34.8 18.3 1.8e-08 34.8 18.3 4.2 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Mnd1 PF03962.15 CBY20432.1 - 2.7e-26 91.6 4.2 2e-25 88.9 0.2 2.7 2 1 1 3 3 3 1 Mnd1 HTH domain LZ3wCH PF18517.1 CBY20432.1 - 2.8e-16 59.3 0.8 2.8e-16 59.3 0.8 2.4 2 0 0 2 2 2 1 Leucine zipper with capping helix domain DsrD PF08679.11 CBY20432.1 - 1.5e-06 28.4 3.2 7.7e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 Dissimilatory sulfite reductase D (DsrD) APG6_N PF17675.1 CBY20432.1 - 0.00025 21.6 3.8 0.00035 21.1 3.8 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region PDDEXK_10 PF07788.11 CBY20432.1 - 0.0067 16.3 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily LCD1 PF09798.9 CBY20432.1 - 0.007 14.9 4.5 0.0092 14.6 4.5 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein Penicillinase_R PF03965.16 CBY20432.1 - 0.015 15.6 0.3 0.062 13.6 0.3 2.0 2 1 0 2 2 2 0 Penicillinase repressor GIT1_C PF12205.8 CBY20432.1 - 0.016 15.3 2.1 0.19 11.8 0.5 2.2 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term TSC22 PF01166.18 CBY20432.1 - 0.024 14.9 3.4 0.024 14.9 3.4 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Spc7 PF08317.11 CBY20432.1 - 0.032 13.1 6.0 0.044 12.7 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 CBY20432.1 - 0.068 13.4 8.0 0.14 12.4 8.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cytochrom_B562 PF07361.11 CBY20432.1 - 0.088 13.5 3.5 0.43 11.3 0.0 2.8 2 1 1 3 3 3 0 Cytochrome b562 CLZ PF16526.5 CBY20432.1 - 0.27 11.6 6.8 6.3 7.2 0.5 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 CBY20432.1 - 0.36 10.6 7.7 0.16 11.8 1.5 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 CBY20432.1 - 0.89 10.0 4.4 10 6.6 1.6 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) F_actin_cap_B PF01115.17 CBY20433.1 - 6.2e-100 333.7 0.0 7.3e-100 333.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit PH PF00169.29 CBY20434.1 - 1.1e-08 35.5 1.5 2e-07 31.5 0.0 2.8 3 1 0 3 3 3 1 PH domain Rho_Binding PF08912.11 CBY20434.1 - 9.7e-07 29.5 3.7 9.7e-07 29.5 3.7 3.6 3 1 2 5 5 5 1 Rho Binding C1_1 PF00130.22 CBY20434.1 - 0.0011 18.8 2.1 0.002 18.0 2.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CBY20434.1 - 0.0051 16.7 1.3 0.012 15.5 1.3 1.6 1 0 0 1 1 1 1 PHD-finger Rx_N PF18052.1 CBY20434.1 - 0.58 10.5 8.7 2.1 8.7 0.2 2.7 2 1 1 3 3 3 0 Rx N-terminal domain Exonuc_VII_L PF02601.15 CBY20434.1 - 3.2 7.3 11.0 5.1 6.6 11.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 CBY20434.1 - 3.7 6.6 12.8 6 5.9 12.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 CBY20434.1 - 4 8.1 21.2 0.13 12.8 7.7 2.9 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Vps54_N PF10475.9 CBY20434.1 - 7.6 5.7 11.4 11 5.1 11.4 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex RRM_1 PF00076.22 CBY20435.1 - 2.6e-14 52.8 0.1 4.7e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDP_N PF12278.8 CBY20435.1 - 3.3 7.9 7.7 7.2 6.8 0.8 2.6 2 1 0 2 2 2 0 Sex determination protein N terminal RRM_1 PF00076.22 CBY20436.1 - 6.9e-13 48.2 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CBY20436.1 - 1.8e-08 34.8 18.3 1.8e-08 34.8 18.3 4.1 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Mnd1 PF03962.15 CBY20437.1 - 1.1e-26 92.9 3.5 2e-25 88.9 0.2 2.7 2 1 1 3 3 3 1 Mnd1 HTH domain LZ3wCH PF18517.1 CBY20437.1 - 6.2e-16 58.2 3.2 6.3e-16 58.2 0.7 2.4 2 0 0 2 2 2 1 Leucine zipper with capping helix domain DsrD PF08679.11 CBY20437.1 - 1.6e-06 28.3 3.2 7.7e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 Dissimilatory sulfite reductase D (DsrD) APG6_N PF17675.1 CBY20437.1 - 0.00028 21.4 3.9 0.00039 20.9 3.9 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region LCD1 PF09798.9 CBY20437.1 - 0.0058 15.2 4.0 0.0075 14.8 4.0 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein PDDEXK_10 PF07788.11 CBY20437.1 - 0.0075 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Penicillinase_R PF03965.16 CBY20437.1 - 0.015 15.6 0.3 0.062 13.6 0.3 2.0 2 1 0 2 2 2 0 Penicillinase repressor Spc7 PF08317.11 CBY20437.1 - 0.017 14.0 5.3 0.024 13.6 5.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GIT1_C PF12205.8 CBY20437.1 - 0.018 15.2 2.1 0.2 11.8 0.5 2.2 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term TSC22 PF01166.18 CBY20437.1 - 0.024 15.0 3.6 0.024 15.0 3.6 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Seryl_tRNA_N PF02403.22 CBY20437.1 - 0.033 14.4 7.0 0.067 13.4 7.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cytochrom_B562 PF07361.11 CBY20437.1 - 0.1 13.2 3.0 0.72 10.5 0.0 2.8 2 1 1 3 3 3 0 Cytochrome b562 CLZ PF16526.5 CBY20437.1 - 0.22 11.9 6.4 6.1 7.3 0.8 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 CBY20437.1 - 0.37 10.6 7.3 0.19 11.5 1.2 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 CBY20437.1 - 0.89 10.0 4.4 10 6.6 1.6 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) F_actin_cap_B PF01115.17 CBY20438.1 - 1.3e-99 332.7 0.0 1.5e-99 332.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DnaJ_C PF01556.18 CBY20439.1 - 9.6e-29 100.4 0.0 1.3e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBY20439.1 - 0.0016 18.8 1.7 0.0041 17.4 1.7 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBY20439.1 - 0.12 12.4 1.4 0.36 10.8 1.4 1.8 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Sulfotransfer_2 PF03567.14 CBY20440.1 - 3e-45 155.1 2.6 4.3e-45 154.6 2.6 1.2 1 0 0 1 1 1 1 Sulfotransferase family HEPN_Swt1 PF18731.1 CBY20440.1 - 0.025 14.9 0.5 4 7.8 0.0 2.5 2 1 0 2 2 2 0 Swt1-like HEPN VAPB_antitox PF02697.14 CBY20440.1 - 0.081 13.7 0.0 2.2 9.1 0.0 3.1 3 0 0 3 3 3 0 Putative antitoxin TAP_C PF03943.13 CBY20441.1 - 9.5e-19 66.8 1.7 9.5e-19 66.8 1.7 2.1 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.7 CBY20441.1 - 0.0047 17.3 6.5 0.034 14.6 2.8 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) UBA_4 PF14555.6 CBY20441.1 - 0.034 14.0 0.1 0.083 12.7 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain DUF4603 PF15376.6 CBY20441.1 - 7.5 3.8 7.1 10 3.3 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) WBP-1 PF11669.8 CBY20443.1 - 0.046 14.4 0.6 0.096 13.3 0.2 1.7 2 0 0 2 2 2 0 WW domain-binding protein 1 TssO PF17561.2 CBY20443.1 - 0.082 13.0 0.4 0.16 12.1 0.1 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssO TTL PF03133.15 CBY20444.1 - 2.6e-85 286.1 0.7 2.6e-85 286.1 0.7 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY20444.1 - 1e-11 44.6 0.3 1.3e-06 27.8 0.0 3.5 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY20444.1 - 1.3e-05 24.6 0.0 0.0075 15.6 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 CBY20444.1 - 0.0049 16.9 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain DUF4585 PF15232.6 CBY20445.1 - 0.007 16.4 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4585) LEA_3 PF03242.13 CBY20445.1 - 1.2 9.9 4.1 9.3 7.0 0.0 2.9 2 1 0 2 2 2 0 Late embryogenesis abundant protein zf-H2C2_2 PF13465.6 CBY20447.1 - 4e-13 49.1 11.3 1.4e-07 31.6 1.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY20447.1 - 4.3e-11 42.6 13.5 1.3e-05 25.4 1.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY20447.1 - 5.1e-07 30.0 11.9 0.00086 20.0 1.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CBY20447.1 - 1.3e-06 28.6 4.9 0.011 16.2 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY20447.1 - 4.7e-06 26.7 0.4 0.019 15.2 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CBY20447.1 - 5.4e-06 26.1 11.9 3.1e-05 23.6 1.3 3.2 3 1 0 3 3 3 2 C2H2-type zinc-finger domain Actin_micro PF17003.5 CBY20447.1 - 6.2e-05 22.3 1.4 0.0013 18.0 0.5 2.0 1 1 1 2 2 2 1 Putative actin-like family zf-C2H2_8 PF15909.5 CBY20447.1 - 0.00022 21.5 1.8 0.00026 21.2 1.8 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 CBY20447.1 - 0.00044 20.6 5.8 0.015 15.7 0.2 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 CBY20447.1 - 0.0013 18.7 9.4 0.043 13.8 0.3 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CBY20447.1 - 0.0069 16.7 3.5 0.99 9.8 0.2 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) DUF1163 PF06651.11 CBY20447.1 - 0.0089 16.1 0.2 0.08 13.0 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1163) ZZ PF00569.17 CBY20447.1 - 0.021 14.6 0.3 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-CSL PF05207.13 CBY20447.1 - 0.023 14.4 0.2 0.045 13.5 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger Zn-ribbon_8 PF09723.10 CBY20447.1 - 0.04 14.0 2.1 0.41 10.8 2.2 2.1 1 1 1 2 2 2 0 Zinc ribbon domain GATA PF00320.27 CBY20447.1 - 0.052 13.2 0.1 10 5.8 0.0 2.3 2 0 0 2 2 2 0 GATA zinc finger zf-C2H2_3rep PF18868.1 CBY20447.1 - 0.06 14.0 1.8 6.8 7.4 0.2 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zf_RING PF16744.5 CBY20447.1 - 0.065 13.3 1.9 0.49 10.5 0.7 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger zf_UBZ PF18439.1 CBY20447.1 - 0.066 12.8 1.6 3.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 CBY20447.1 - 0.068 13.0 0.3 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 CBY20447.1 - 0.09 12.4 2.5 3.5 7.3 0.4 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met2 PF12907.7 CBY20447.1 - 0.4 10.9 3.7 4.9 7.4 0.3 2.4 2 0 0 2 2 2 0 Zinc-binding GAGA PF09237.11 CBY20447.1 - 0.61 9.9 5.6 4.5 7.1 0.4 2.1 1 1 1 2 2 2 0 GAGA factor zf-CHY PF05495.12 CBY20447.1 - 0.96 10.0 5.3 1.4 9.5 1.6 2.0 1 1 1 2 2 2 0 CHY zinc finger O-FucT PF10250.9 CBY20448.1 - 0.00027 20.7 0.2 0.00072 19.4 0.2 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Img2 PF05046.14 CBY20448.1 - 0.057 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) SNF PF00209.18 CBY20449.1 - 1.5e-158 528.8 38.5 1.7e-158 528.6 38.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RhoGAP PF00620.27 CBY20450.1 - 7.9e-26 90.7 0.0 1.9e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Syntaxin-6_N PF09177.11 CBY20450.1 - 0.094 13.3 4.6 0.56 10.8 4.6 2.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal PSS PF03034.15 CBY20451.1 - 2.8e-104 348.7 14.4 3.9e-104 348.2 14.4 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase Pox_F11 PF04943.12 CBY20452.1 - 0.5 9.4 2.5 0.36 9.9 0.5 1.6 2 0 0 2 2 2 0 Poxvirus F11 protein SAM_3 PF18016.1 CBY20453.1 - 5.6e-11 42.1 0.0 9.5e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SVIP PF15811.5 CBY20453.1 - 0.027 14.9 2.0 0.64 10.5 0.0 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein SAM_2 PF07647.17 CBY20453.1 - 0.05 13.7 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ion_trans PF00520.31 CBY20454.1 - 7.1e-24 84.4 16.9 9.7e-24 83.9 16.9 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY20454.1 - 4.7e-11 42.5 3.4 4.7e-11 42.5 3.4 2.1 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 CBY20454.1 - 1.4e-05 25.1 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_9 PF13426.7 CBY20455.1 - 4.7e-07 30.0 0.0 5.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 CBY20455.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 PAS fold Ank_2 PF12796.7 CBY20456.1 - 1.8e-55 185.5 33.1 2.4e-10 40.9 0.1 10.8 4 3 7 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY20456.1 - 3.8e-50 167.6 22.2 3.4e-06 27.5 0.1 15.1 8 5 9 17 17 17 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY20456.1 - 3.6e-38 129.1 18.1 7.8e-07 29.3 0.3 13.5 9 4 6 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY20456.1 - 1.4e-36 120.3 17.6 0.025 15.1 0.1 19.2 22 0 0 22 22 22 9 Ankyrin repeat Ank PF00023.30 CBY20456.1 - 8.2e-30 101.9 21.6 0.0056 17.1 0.1 16.2 17 1 0 17 17 17 5 Ankyrin repeat FYVE PF01363.21 CBY20456.1 - 1.3e-13 50.8 6.9 1.3e-13 50.8 6.9 1.9 2 0 0 2 2 2 1 FYVE zinc finger BTB PF00651.31 CBY20456.1 - 1e-09 38.6 0.6 2.4e-09 37.4 0.2 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF2482 PF10655.9 CBY20456.1 - 1.3 9.6 5.0 1.1 9.8 1.4 2.8 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) PKD_channel PF08016.12 CBY20457.1 - 6.4e-26 91.0 7.7 6.4e-26 91.0 7.7 1.7 2 0 0 2 2 2 1 Polycystin cation channel EGF_CA PF07645.15 CBY20457.1 - 6.1e-07 29.5 9.0 6.1e-07 29.5 9.0 8.4 7 3 3 10 10 10 1 Calcium-binding EGF domain Ephrin_rec_like PF07699.13 CBY20457.1 - 0.00012 21.8 138.7 0.0013 18.4 7.2 13.2 3 2 12 16 16 16 10 Putative ephrin-receptor like cEGF PF12662.7 CBY20457.1 - 0.0008 19.3 0.6 0.0008 19.3 0.6 8.9 11 1 1 12 12 12 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY20457.1 - 0.0012 19.1 8.7 0.0012 19.1 8.7 8.8 9 2 0 9 9 9 2 Coagulation Factor Xa inhibitory site CitMHS PF03600.16 CBY20457.1 - 0.087 12.0 8.9 0.24 10.5 1.5 2.3 2 0 0 2 2 2 0 Citrate transporter HDNR PF15115.6 CBY20458.1 - 0.009 16.3 3.6 0.061 13.6 3.6 2.1 1 1 0 1 1 1 1 Domain of unknown function with conserved HDNR motif RRM_1 PF00076.22 CBY20461.1 - 1.9e-22 78.8 0.0 2.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY20461.1 - 0.00049 19.7 0.0 0.00063 19.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY20461.1 - 0.0055 16.8 0.0 0.0083 16.2 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif BRAP2 PF07576.12 CBY20461.1 - 0.012 15.8 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 BRCA1-associated protein 2 Cpn60_TCP1 PF00118.24 CBY20462.1 - 4.5e-137 457.7 7.5 5.2e-137 457.4 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 CBY20462.1 - 0.045 13.3 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 Propionate catabolism activator Tctex-1 PF03645.13 CBY20463.1 - 9.4e-21 74.0 0.0 1.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Aminotran_3 PF00202.21 CBY20464.1 - 1.5e-97 326.8 0.0 1.9e-97 326.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Metal_hydrol PF10118.9 CBY20464.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase MRP-S32 PF10210.9 CBY20464.1 - 0.1 13.2 0.2 0.2 12.2 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 WD40 PF00400.32 CBY20465.1 - 3.5e-14 53.0 5.0 0.00024 21.9 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20465.1 - 1.3e-13 51.0 0.1 6.7e-07 29.5 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY20465.1 - 0.0046 16.9 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBY20465.1 - 0.0059 15.6 0.1 0.76 8.7 0.1 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CBY20465.1 - 0.055 13.4 0.1 20 5.2 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Myb_Cef PF11831.8 CBY20466.1 - 1.9e-63 214.2 0.5 1.9e-63 214.2 0.5 3.9 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CBY20466.1 - 1.9e-19 69.6 6.2 1.3e-10 41.3 1.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY20466.1 - 3.3e-19 68.9 3.8 3.9e-13 49.4 3.7 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 CBY20466.1 - 1.1 9.4 4.2 2.4 8.3 0.2 3.3 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Proteasome PF00227.26 CBY20467.1 - 1.1e-58 197.9 0.0 1.4e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBY20467.1 - 1.5e-09 37.4 0.0 2.5e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CLASP_N PF12348.8 CBY20469.1 - 1e-11 44.9 9.2 8.3e-06 25.5 0.6 3.1 3 0 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 CBY20469.1 - 0.00016 21.8 0.2 0.018 15.2 0.0 3.8 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CBY20469.1 - 0.00016 22.2 1.7 0.0088 16.6 0.1 3.8 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CBY20469.1 - 0.00017 21.6 5.3 0.0081 16.2 0.2 3.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY20469.1 - 0.0023 18.3 0.1 3.9 7.9 0.0 4.3 4 0 0 4 4 4 1 HEAT repeats Adaptin_N PF01602.20 CBY20469.1 - 0.003 16.2 3.8 0.22 10.0 0.3 3.1 3 0 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 CBY20469.1 - 0.018 14.2 0.5 0.018 14.2 0.5 2.3 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CBY20469.1 - 0.034 14.4 0.4 97 3.6 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat FAD-SLDH PF12318.8 CBY20469.1 - 0.058 13.5 0.4 0.82 9.7 0.0 2.6 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase CNOT11 PF10155.9 CBY20469.1 - 0.22 11.7 6.2 3.1 8.0 0.7 4.1 4 1 0 4 4 4 0 CCR4-NOT transcription complex subunit 11 Neur_chan_memb PF02932.16 CBY20469.1 - 6.4 6.8 8.0 2.1 8.4 0.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CLASP_N PF12348.8 CBY20470.1 - 7.9e-14 51.8 1.1 7.5e-07 28.9 0.3 2.8 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 CBY20470.1 - 2e-07 30.7 3.0 0.36 11.2 0.0 6.5 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 CBY20470.1 - 0.00097 19.2 5.3 0.84 9.7 0.1 5.0 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CBY20470.1 - 0.0017 18.8 1.2 1.7 9.3 0.1 4.2 3 0 0 3 3 3 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CBY20470.1 - 0.0019 18.7 0.0 20 5.8 0.0 4.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Sigma_1s PF02454.16 CBY20470.1 - 0.054 13.5 0.1 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Sigma 1s protein YqfQ PF14181.6 CBY20470.1 - 1.5 9.0 5.0 3.5 7.8 5.0 1.6 1 0 0 1 1 1 0 YqfQ-like protein Ribosomal_L39 PF00832.20 CBY20471.1 - 4.3e-22 77.5 8.3 5.1e-22 77.2 8.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 CBY20471.1 - 0.037 13.6 0.3 0.041 13.4 0.3 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 RNA_pol_Rpc34 PF05158.12 CBY20472.1 - 2.7e-34 119.1 0.0 5.4e-32 111.5 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 CBY20472.1 - 0.0027 17.8 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 CBY20472.1 - 0.056 13.3 0.1 0.32 10.9 0.0 2.2 2 1 0 2 2 2 0 MarR family Ribosomal_60s PF00428.19 CBY20473.1 - 9.5e-23 80.6 2.7 1.1e-22 80.4 2.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ODC_AZ PF02100.17 CBY20474.1 - 9.1e-06 25.6 0.1 1.2e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme PDZ PF00595.24 CBY20475.1 - 1.4e-26 92.7 0.4 8.6e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY20475.1 - 1e-12 47.7 0.1 2.5e-06 27.2 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY20475.1 - 4.7e-10 39.7 0.1 8e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Homeodomain PF00046.29 CBY20476.1 - 1.1e-20 73.2 3.1 2.6e-20 72.0 3.1 1.7 1 0 0 1 1 1 1 Homeodomain SCO1-SenC PF02630.14 CBY20477.1 - 0.45 10.4 1.9 13 5.7 0.3 2.9 2 0 0 2 2 2 0 SCO1/SenC Abhydrolase_1 PF00561.20 CBY20478.1 - 8.6e-06 25.6 0.0 9.2e-05 22.2 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBY20478.1 - 0.01 15.1 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBY20478.1 - 0.031 14.9 0.0 0.16 12.6 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Kelch_1 PF01344.25 CBY20479.1 - 0.001 18.6 0.4 2.3 7.8 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Band_7 PF01145.25 CBY20480.1 - 1.2e-26 93.8 5.3 1.7e-26 93.3 5.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY20480.1 - 0.0079 15.9 0.3 0.012 15.3 0.3 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family RNA12 PF10443.9 CBY20481.1 - 0.094 11.4 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 RNA12 protein ALMT PF11744.8 CBY20481.1 - 0.41 9.4 2.9 0.2 10.5 0.8 1.4 2 0 0 2 2 2 0 Aluminium activated malate transporter DASH_Dam1 PF08653.10 CBY20481.1 - 0.74 9.7 4.8 15 5.5 0.0 4.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 HR1 PF02185.16 CBY20481.1 - 3.7 7.7 8.5 7.3 6.8 0.6 3.3 3 0 0 3 3 3 0 Hr1 repeat Connexin PF00029.19 CBY20482.1 - 7.8e-21 74.9 3.0 5.1e-20 72.2 3.0 2.1 1 1 0 1 1 1 1 Connexin Jiraiya PF15038.6 CBY20482.1 - 0.012 15.0 0.7 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Jiraiya BLOC1_2 PF10046.9 CBY20483.1 - 0.0067 16.7 2.1 0.01 16.1 2.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_min_cap2 PF06152.11 CBY20483.1 - 0.0083 15.1 1.5 0.0097 14.8 1.5 1.1 1 0 0 1 1 1 1 Phage minor capsid protein 2 ZapB PF06005.12 CBY20483.1 - 0.063 13.7 6.3 0.14 12.6 6.2 1.7 1 1 0 1 1 1 0 Cell division protein ZapB HrpB7 PF09486.10 CBY20483.1 - 0.16 12.4 7.3 0.27 11.6 7.3 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF3450 PF11932.8 CBY20483.1 - 0.17 11.2 4.3 0.22 10.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ORF6C PF10552.9 CBY20483.1 - 0.3 11.2 4.2 0.36 10.9 2.7 1.9 1 1 1 2 2 2 0 ORF6C domain CENP-H PF05837.12 CBY20483.1 - 0.36 11.3 3.9 0.53 10.7 3.9 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 CBY20483.1 - 0.75 9.9 9.1 0.95 9.5 9.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 CBY20483.1 - 1.7 9.1 7.7 0.84 10.1 0.6 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Seadorna_VP6 PF07407.11 CBY20483.1 - 2.9 6.8 6.8 3.5 6.5 6.8 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DivIC PF04977.15 CBY20483.1 - 5.1 6.9 12.5 0.91 9.3 2.8 3.0 1 1 2 3 3 3 0 Septum formation initiator DUF4500 PF14937.6 CBY20484.1 - 0.028 14.4 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) PTCB-BRCT PF12738.7 CBY20486.1 - 1.2e-50 169.3 0.7 2.1e-18 66.0 0.1 6.0 6 0 0 6 6 6 5 twin BRCT domain BRCT PF00533.26 CBY20486.1 - 1.1e-44 150.7 0.1 8e-10 39.0 0.0 7.0 7 0 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBY20486.1 - 5.9e-32 109.9 0.3 3e-05 24.4 0.3 7.4 7 0 0 7 7 7 6 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY20486.1 - 2.6e-09 37.2 1.0 0.033 14.5 0.0 5.9 7 0 0 7 7 7 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 CBY20486.1 - 2.5e-08 33.9 0.3 0.018 15.1 0.1 4.8 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain Peptidase_M18 PF02127.15 CBY20487.1 - 4.9e-165 549.5 0.0 5.8e-165 549.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CBY20487.1 - 8.1e-08 31.6 0.3 6.5e-05 22.1 0.2 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase FlgT_C PF16538.5 CBY20487.1 - 0.012 16.1 0.1 1.7 9.3 0.0 2.5 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain EMP24_GP25L PF01105.24 CBY20488.1 - 4.4e-50 170.2 0.1 4.9e-50 170.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF669 PF05037.13 CBY20488.1 - 0.031 14.4 0.2 22 5.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF669) TPT PF03151.16 CBY20490.1 - 2.2e-74 250.4 28.8 2.5e-74 250.3 28.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY20490.1 - 1.1e-16 61.2 31.8 2.2e-08 34.4 13.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CBY20490.1 - 2.3e-05 23.8 22.1 2.8e-05 23.5 22.1 1.2 1 0 0 1 1 1 1 UAA transporter family Abhydrolase_1 PF00561.20 CBY20491.1 - 5.6e-15 55.7 0.0 6.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY20491.1 - 1.8e-10 41.8 0.0 2.2e-10 41.5 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBY20491.1 - 6.1e-08 32.2 0.0 1.3e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase PF00151.19 CBY20491.1 - 0.0099 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipase DUF915 PF06028.11 CBY20491.1 - 0.01 15.2 0.1 0.51 9.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 CBY20491.1 - 0.041 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 CBY20491.1 - 0.046 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF434 PF04256.12 CBY20491.1 - 0.06 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Abhydrolase_5 PF12695.7 CBY20491.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY20491.1 - 0.15 12.1 0.1 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Histone_H2A_C PF16211.5 CBY20492.1 - 3.1e-17 62.0 0.5 5.8e-17 61.1 0.1 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CBY20492.1 - 6.1e-10 39.6 0.0 8.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY20492.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Thyroglobulin_1 PF00086.18 CBY20493.1 - 2.3e-42 142.5 52.3 9.1e-11 41.3 0.2 7.3 6 1 1 7 7 7 5 Thyroglobulin type-1 repeat SRCR PF00530.18 CBY20493.1 - 6e-24 84.5 13.3 1.3e-13 51.3 0.0 4.8 4 1 1 5 5 5 3 Scavenger receptor cysteine-rich domain TIL PF01826.17 CBY20493.1 - 1e-07 32.1 35.8 6.5e-06 26.3 12.3 10.3 11 3 1 12 12 12 2 Trypsin Inhibitor like cysteine rich domain SRCR_2 PF15494.6 CBY20493.1 - 6.1e-07 29.9 9.2 0.0054 17.3 0.0 3.5 3 1 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 CBY20493.1 - 1.1e-06 29.1 0.0 0.059 13.9 0.0 3.3 2 0 0 2 2 2 2 Hepsin, SRCR domain ShK PF01549.24 CBY20493.1 - 0.0039 17.7 5.2 0.0039 17.7 5.2 8.7 8 1 1 9 9 9 4 ShK domain-like FGGY_N PF00370.21 CBY20495.1 - 9.3e-17 61.4 0.0 6.8e-15 55.3 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CBY20495.1 - 7.4e-14 51.9 0.0 1.9e-13 50.6 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BAG PF02179.16 CBY20496.1 - 0.042 14.3 0.0 2.3 8.7 0.0 2.6 1 1 0 1 1 1 0 BAG domain VWA PF00092.28 CBY20496.1 - 0.16 12.2 0.4 2.7 8.2 0.2 2.6 2 1 0 2 2 2 0 von Willebrand factor type A domain Pkinase_Tyr PF07714.17 CBY20497.1 - 9.1e-50 169.3 0.0 8.3e-49 166.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY20497.1 - 1.4e-24 86.8 0.0 5.8e-24 84.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.19 CBY20497.1 - 1.8e-18 67.2 0.1 1.7e-11 44.5 0.0 2.8 2 1 1 3 3 3 2 Ephrin receptor ligand binding domain fn3 PF00041.21 CBY20497.1 - 3.7e-15 56.0 0.0 2.4e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Ephrin_rec_like PF07699.13 CBY20497.1 - 1.5e-05 24.7 5.5 1.5e-05 24.7 5.5 2.8 2 1 0 2 2 2 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 CBY20497.1 - 0.00013 22.5 0.0 0.018 15.6 0.0 2.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain cEGF PF12662.7 CBY20497.1 - 0.061 13.3 4.8 1.6 8.7 0.5 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like DUF202 PF02656.15 CBY20497.1 - 0.16 12.5 0.8 0.37 11.2 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) 2OG-FeII_Oxy PF03171.20 CBY20498.1 - 1.9e-18 66.8 0.0 3.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBY20498.1 - 1.4e-13 51.6 0.0 2.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal KIX PF02172.16 CBY20499.1 - 0.019 15.2 0.2 0.028 14.7 0.2 1.3 1 1 0 1 1 1 0 KIX domain DUF3958 PF13125.6 CBY20499.1 - 0.025 14.8 2.0 0.032 14.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Kelch_1 PF01344.25 CBY20500.1 - 6.2e-15 54.5 2.5 0.00016 21.1 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CBY20500.1 - 5.2e-09 36.1 8.7 0.0057 16.9 0.1 5.3 2 2 4 6 6 6 3 Kelch motif Kelch_4 PF13418.6 CBY20500.1 - 7.1e-09 35.5 3.8 0.022 14.7 0.0 5.6 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY20500.1 - 3.2e-08 33.4 1.0 0.011 15.7 0.1 5.0 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBY20500.1 - 3.2e-05 23.7 4.5 3 8.0 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CBY20500.1 - 0.0001 22.5 6.0 0.6 10.5 0.0 5.0 6 0 0 6 6 6 1 Galactose oxidase, central domain PEX11 PF05648.14 CBY20500.1 - 0.22 11.0 0.1 1.6 8.2 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) NUDIX PF00293.28 CBY20501.1 - 7.6e-07 29.2 0.1 1.2e-06 28.6 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain Connexin PF00029.19 CBY20502.1 - 2.4e-89 299.1 4.2 2.4e-89 299.1 4.2 1.6 2 0 0 2 2 2 1 Connexin DUF4834 PF16118.5 CBY20502.1 - 0.2 12.6 5.3 10 7.2 1.7 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4834) Lipase_3 PF01764.25 CBY20503.1 - 2.2e-20 73.0 0.0 3.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CBY20503.1 - 0.063 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 CBY20503.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 CBY20503.1 - 0.16 11.5 0.0 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) TipE PF16972.5 CBY20504.1 - 0.029 13.6 0.4 0.033 13.4 0.4 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE OPA3 PF07047.12 CBY20504.1 - 0.05 13.4 6.0 0.15 11.8 2.7 2.7 2 1 0 2 2 2 0 Optic atrophy 3 protein (OPA3) DASH_Dad2 PF08654.10 CBY20504.1 - 0.099 13.1 2.6 0.19 12.2 2.6 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 VKOR PF07884.14 CBY20505.1 - 1.3e-19 70.6 9.1 1.9e-19 70.0 9.1 1.3 1 0 0 1 1 1 1 Vitamin K epoxide reductase family LIM PF00412.22 CBY20505.1 - 4.1 7.7 9.0 0.28 11.5 3.1 2.2 2 0 0 2 2 2 0 LIM domain CCB1 PF12046.8 CBY20505.1 - 4.2 6.7 6.5 0.21 10.9 0.5 1.8 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B TIG PF01833.24 CBY20506.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 IPT/TIG domain DUF4107 PF13389.6 CBY20507.1 - 0.076 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) RhoGEF PF00621.20 CBY20508.1 - 5.3e-21 75.7 1.5 5.3e-21 75.7 1.5 2.8 3 2 0 3 3 3 1 RhoGEF domain GATA PF00320.27 CBY20510.1 - 0.12 12.0 0.3 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 GATA zinc finger HAP1_N PF04849.13 CBY20511.1 - 0.0018 17.5 11.1 0.0018 17.5 11.1 5.3 2 1 2 4 4 4 1 HAP1 N-terminal conserved region DUF4806 PF16064.5 CBY20511.1 - 0.044 14.1 0.2 0.044 14.1 0.2 4.6 5 2 0 5 5 5 0 Domain of unknown function (DUF4806) TMF_DNA_bd PF12329.8 CBY20512.1 - 0.016 15.2 3.2 0.016 15.2 3.2 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding Tap-RNA_bind PF09162.10 CBY20512.1 - 0.21 11.5 3.5 10 6.0 0.1 2.9 2 1 0 2 2 2 0 Tap, RNA-binding PI_PP_I PF18363.1 CBY20512.1 - 0.98 9.6 9.7 0.62 10.3 2.6 2.8 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain GCOM2 PF15328.6 CBY20514.1 - 5.2e-08 33.5 8.7 1.3e-07 32.2 8.7 2.0 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 DUF2113 PF09886.9 CBY20514.1 - 0.0012 18.2 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2113) Amino_oxidase PF01593.24 CBY20516.1 - 1.1e-33 117.3 0.0 4.6e-33 115.2 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CBY20516.1 - 1.4e-12 47.6 0.0 3.3e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CBY20516.1 - 4.5e-05 22.9 0.1 8e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY20516.1 - 0.00063 19.1 0.6 0.02 14.2 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CBY20516.1 - 0.001 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY20516.1 - 0.0014 17.8 0.2 0.0027 16.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CBY20516.1 - 0.0025 17.2 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase eIF3_p135 PF12807.7 CBY20516.1 - 0.0033 17.5 0.1 0.0062 16.6 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 DAO PF01266.24 CBY20516.1 - 0.004 16.8 0.7 0.01 15.4 0.8 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CBY20516.1 - 0.0066 15.6 1.3 0.018 14.1 0.3 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBY20516.1 - 0.019 13.7 0.2 0.034 12.8 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 CBY20516.1 - 0.024 13.9 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 CBY20516.1 - 0.035 14.7 0.1 0.077 13.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GatB_Yqey PF02637.18 CBY20518.1 - 0.071 13.0 4.4 1.7 8.5 0.8 3.2 2 1 1 3 3 3 0 GatB domain Histone PF00125.24 CBY20519.1 - 4.1e-19 69.3 0.1 5.2e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY20519.1 - 5.2e-06 26.7 0.3 9.3e-06 25.8 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 CBY20519.1 - 0.00032 20.8 0.1 0.00037 20.5 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 CBY20519.1 - 0.00047 20.6 0.0 0.00083 19.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF3915 PF13054.6 CBY20519.1 - 0.0013 18.7 0.0 0.0016 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) AT_hook PF02178.19 CBY20519.1 - 0.087 12.7 2.3 0.087 12.7 2.3 2.5 2 0 0 2 2 2 0 AT hook motif GMP_synt_C PF00958.22 CBY20519.1 - 0.12 12.5 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 GMP synthase C terminal domain Histone_H2A_C PF16211.5 CBY20520.1 - 7.8e-18 63.9 0.7 1.5e-17 63.0 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY20520.1 - 4.7e-07 30.2 0.9 1.6e-06 28.5 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CBY20521.1 - 2e-20 72.2 1.3 4.1e-20 71.2 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY20521.1 - 5.8e-16 59.0 0.0 7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY20521.1 - 3.8e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBY20522.1 - 3.3e-08 33.6 0.1 4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY20522.1 - 4.7e-05 23.5 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY20522.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY20522.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY20522.1 - 0.00033 21.0 0.2 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY20522.1 - 0.012 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY20522.1 - 0.046 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY20522.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CBY20523.1 - 3.4e-40 137.5 3.5 6.1e-40 136.6 3.5 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY20523.1 - 6.1e-05 23.1 0.2 0.00011 22.3 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CBY20523.1 - 0.00041 20.7 0.0 0.00063 20.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CBY20523.1 - 0.019 15.5 4.8 0.026 15.1 4.8 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CBY20523.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2408 PF10303.9 CBY20523.1 - 0.091 13.3 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) TFIID-31kDa PF02291.15 CBY20523.1 - 0.095 12.8 0.1 0.19 11.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.20 CBY20524.1 - 2.6e-11 43.4 0.1 1.5e-09 37.8 0.0 3.2 4 0 0 4 4 4 1 Thioredoxin Thioredoxin_6 PF13848.6 CBY20524.1 - 9.6e-09 35.4 6.7 4.2e-07 30.0 1.6 3.6 2 2 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY20524.1 - 6.6e-05 23.2 3.2 0.00014 22.2 0.0 2.9 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBY20524.1 - 0.062 13.7 0.3 0.69 10.4 0.1 2.9 4 1 0 4 4 4 0 Thioredoxin-like domain UPF0183 PF03676.14 CBY20526.1 - 9.5e-122 407.1 0.1 3.2e-120 402.0 0.1 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) DP PF08781.10 CBY20527.1 - 6.6e-36 123.2 2.8 1.4e-35 122.2 2.8 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 CBY20527.1 - 2.9e-17 62.5 0.1 6.9e-17 61.3 0.1 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain FGGY_N PF00370.21 CBY20527.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Chorein_N PF12624.7 CBY20528.1 - 1.7e-15 57.2 1.2 2.7e-14 53.3 0.2 2.8 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 zf-RING_UBOX PF13445.6 CBY20529.1 - 0.0086 16.1 1.5 0.018 15.1 1.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY20529.1 - 0.029 14.7 2.0 0.056 13.8 2.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 CBY20529.1 - 0.034 13.9 0.4 0.063 13.0 0.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger OST3_OST6 PF04756.13 CBY20529.1 - 0.049 13.0 0.4 0.049 13.0 0.4 1.4 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family zf-RING_5 PF14634.6 CBY20529.1 - 0.15 12.0 2.5 0.38 10.7 2.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain E2F_CC-MB PF16421.5 CBY20531.1 - 1.5e-24 86.1 0.0 3.9e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 CBY20531.1 - 4.2e-22 78.0 0.0 8.9e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 CBY20531.1 - 0.0019 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TMEM18 PF14770.6 CBY20532.1 - 3.4e-23 81.9 3.6 3.7e-23 81.7 3.6 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 Myosin_head PF00063.21 CBY20534.1 - 2e-265 882.3 0.0 2e-265 882.3 0.0 3.6 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY20534.1 - 3.2e-58 197.5 233.3 4e-58 197.1 233.3 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY20534.1 - 0.00051 19.8 0.9 0.0015 18.3 0.9 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CBY20534.1 - 0.11 12.7 0.0 0.11 12.7 0.0 4.5 5 1 0 5 5 5 0 AAA domain Sulfatase PF00884.23 CBY20536.1 - 1.6e-60 205.1 0.3 2.1e-60 204.7 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY20536.1 - 1.3e-06 28.2 0.1 0.0048 16.5 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CBY20536.1 - 3.9e-05 22.5 0.0 6.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 CBY20536.1 - 5e-05 23.5 0.1 0.12 12.6 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) PMP22_Claudin PF00822.20 CBY20537.1 - 3.8e-17 62.7 2.3 4.7e-17 62.4 2.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY20537.1 - 4.4e-10 39.6 0.5 1.3e-09 38.1 0.5 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 CBY20537.1 - 4.8e-05 23.6 0.8 7.6e-05 23.0 0.8 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 CBY20537.1 - 0.013 14.9 0.4 0.038 13.5 0.0 1.9 1 1 0 1 1 1 0 Clc-like GIDE PF12483.8 CBY20537.1 - 0.038 13.4 0.1 0.073 12.5 0.1 1.4 1 0 0 1 1 1 0 E3 Ubiquitin ligase Amastin PF07344.11 CBY20537.1 - 0.04 13.8 0.3 0.11 12.3 0.3 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF4064 PF13273.6 CBY20537.1 - 0.058 13.7 15.2 0.025 14.9 8.7 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) Claudin_3 PF06653.11 CBY20537.1 - 0.15 11.9 4.4 1.1 9.2 4.1 2.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like SUR7 PF06687.12 CBY20537.1 - 0.18 11.4 1.6 9.2 5.8 0.1 2.2 1 1 0 2 2 2 0 SUR7/PalI family Tetraspanin PF00335.20 CBY20537.1 - 1.3 8.7 8.4 0.69 9.6 0.5 2.2 2 0 0 2 2 2 0 Tetraspanin family Trypan_PARP PF05887.11 CBY20538.1 - 0.00024 21.1 18.2 0.00041 20.3 18.2 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) GKAP PF03359.13 CBY20538.1 - 0.049 13.2 4.7 0.072 12.6 4.7 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein DUF913 PF06025.12 CBY20538.1 - 0.22 10.5 1.0 0.27 10.2 1.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CBY20538.1 - 0.25 10.1 0.1 0.31 9.7 0.1 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CBY20538.1 - 2 7.0 5.0 2.6 6.6 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1126 PF06565.12 CBY20539.1 - 1.2e-79 262.9 0.4 6.7e-30 103.0 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain Kazal_2 PF07648.15 CBY20540.1 - 5.6e-40 135.2 95.2 8.9e-10 38.5 2.8 9.1 8 0 0 8 8 8 6 Kazal-type serine protease inhibitor domain Laminin_G_2 PF02210.24 CBY20540.1 - 5.6e-31 107.7 0.2 7.7e-15 55.6 0.0 3.5 3 0 0 3 3 3 3 Laminin G domain Kazal_1 PF00050.21 CBY20540.1 - 8.8e-23 80.1 74.2 7e-07 29.2 11.6 7.1 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain Laminin_G_1 PF00054.23 CBY20540.1 - 3.4e-21 75.8 0.0 1.3e-13 51.3 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_EGF PF00053.24 CBY20540.1 - 0.00012 22.2 35.4 0.00034 20.7 15.4 8.4 7 4 3 10 10 10 2 Laminin EGF domain DUF5010_C PF18099.1 CBY20540.1 - 0.22 11.7 0.1 7.9 6.6 0.0 2.4 2 0 0 2 2 2 0 DUF5010 C-terminal domain ShK PF01549.24 CBY20541.1 - 0.0022 18.5 4.7 0.0022 18.5 4.7 1.7 2 0 0 2 2 2 1 ShK domain-like Sid-5 PF17204.3 CBY20541.1 - 0.03 14.5 0.2 0.066 13.4 0.2 1.5 1 0 0 1 1 1 0 Sid-5 family Flp1_like PF16982.5 CBY20541.1 - 0.086 12.3 1.8 0.59 9.6 0.3 2.3 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lipin_N PF04571.14 CBY20542.1 - 1.3e-39 134.2 0.0 1.9e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 lipin, N-terminal conserved region LNS2 PF08235.13 CBY20543.1 - 5.5e-95 317.1 0.0 8.7e-95 316.5 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_mid PF16876.5 CBY20543.1 - 3.5e-22 78.5 0.1 8.3e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Acid_phosphat_B PF03767.14 CBY20543.1 - 0.048 13.2 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) zf-C4 PF00105.18 CBY20544.1 - 2.5e-31 107.9 17.3 4.1e-31 107.2 17.3 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY20544.1 - 4.2e-17 62.4 0.1 8.6e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Sugar_tr PF00083.24 CBY20545.1 - 4.5e-26 91.7 19.3 5.6e-26 91.4 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY20545.1 - 2.2e-13 49.9 33.0 3.1e-08 32.9 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF808 PF05661.12 CBY20545.1 - 0.015 14.4 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Sulfotransfer_2 PF03567.14 CBY20546.1 - 1.6e-15 57.7 5.6 2.6e-15 57.0 5.6 1.2 1 0 0 1 1 1 1 Sulfotransferase family Hus1 PF04005.12 CBY20548.1 - 6.5e-42 143.6 0.1 7.9e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein Aminotran_1_2 PF00155.21 CBY20549.1 - 1.5e-86 290.9 0.0 1.6e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3236 PF11576.8 CBY20549.1 - 0.023 14.4 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Pkinase_Tyr PF07714.17 CBY20550.1 - 3.7e-51 173.9 0.0 5.1e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY20550.1 - 9.2e-32 110.4 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CBY20550.1 - 4.9e-10 39.4 0.2 1.2e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 SH2 domain Pkinase_fungal PF17667.1 CBY20550.1 - 0.0028 16.5 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SH2_2 PF14633.6 CBY20550.1 - 0.023 14.1 0.0 0.058 12.8 0.0 1.6 1 1 0 1 1 1 0 SH2 domain Kinase-like PF14531.6 CBY20550.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GST_C_2 PF13410.6 CBY20551.1 - 9.4e-07 28.8 0.0 3.7e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CBY20551.1 - 2.5e-06 27.7 0.0 4.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY20551.1 - 0.00097 19.5 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY20551.1 - 0.018 15.2 0.0 0.039 14.2 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY20551.1 - 0.038 14.2 0.0 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Sybindin PF04099.12 CBY20552.1 - 4.8e-38 130.3 0.0 5.7e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CBY20552.1 - 5.6e-07 29.7 0.0 9.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Band_7 PF01145.25 CBY20554.1 - 0.018 15.0 1.6 0.97 9.4 0.5 2.6 1 1 1 2 2 2 0 SPFH domain / Band 7 family ZYG-11_interact PF05884.12 CBY20554.1 - 0.21 11.0 0.1 0.27 10.6 0.1 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Abhydrolase_1 PF00561.20 CBY20555.1 - 0.0085 15.8 0.0 0.02 14.5 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 CBY20555.1 - 0.016 14.7 0.1 0.055 13.0 0.1 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase ADK PF00406.22 CBY20556.1 - 5.7e-43 146.6 0.0 6.8e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBY20556.1 - 1e-18 68.1 0.1 1.7e-18 67.4 0.0 1.4 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CBY20556.1 - 7.8e-15 54.6 0.0 1.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CBY20556.1 - 0.0089 16.6 0.0 0.027 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBY20556.1 - 0.024 14.9 0.1 0.041 14.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBY20556.1 - 0.025 14.7 0.2 0.13 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 CBY20556.1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF4200 PF13863.6 CBY20557.1 - 2.2e-32 111.9 24.8 2.2e-32 111.9 24.8 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) DUF4407 PF14362.6 CBY20557.1 - 7.8 5.8 25.1 8.9e+03 -4.3 25.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CEP63 PF17045.5 CBY20558.1 - 8e-09 35.8 23.5 2.8e-05 24.1 0.3 4.1 1 1 3 4 4 4 3 Centrosomal protein of 63 kDa Tektin PF03148.14 CBY20558.1 - 0.083 11.6 23.6 0.059 12.1 20.7 2.0 1 1 1 2 2 2 0 Tektin family Period_C PF12114.8 CBY20558.1 - 0.12 12.0 2.2 5.1 6.6 0.5 2.3 2 0 0 2 2 2 0 Period protein 2/3C-terminal region HALZ PF02183.18 CBY20558.1 - 0.35 11.1 14.5 3.9 7.8 1.9 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 CBY20558.1 - 0.47 10.6 18.4 23 5.1 9.3 3.7 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF812 PF05667.11 CBY20558.1 - 0.74 8.6 23.0 1.7 7.5 23.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TSC22 PF01166.18 CBY20558.1 - 1.9 8.9 11.2 13 6.2 0.2 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family Golgin_A5 PF09787.9 CBY20558.1 - 2.8 7.3 20.8 3.6 7.0 1.7 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Spc24 PF08286.11 CBY20558.1 - 3.5 7.9 16.1 3.5 7.9 0.6 3.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Exonuc_VII_L PF02601.15 CBY20558.1 - 3.5 7.1 8.9 7 6.1 8.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CBY20558.1 - 3.7 6.8 15.9 3.7 6.8 14.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF465 PF04325.13 CBY20558.1 - 9.3 6.4 15.8 2.1 8.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF465) V_ATPase_I PF01496.19 CBY20558.1 - 9.9 3.9 13.7 14 3.5 13.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3695 PF12494.8 CBY20560.1 - 1.3e-18 66.7 0.3 5.6e-18 64.6 0.3 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) Mito_carr PF00153.27 CBY20561.1 - 2.8e-24 84.8 0.4 7.9e-16 57.8 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial carrier protein Fcf1 PF04900.12 CBY20563.1 - 1.6e-37 127.9 1.2 2.3e-37 127.4 1.2 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CBY20563.1 - 1.6e-13 51.0 0.0 3.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 PIN like domain 7TM_GPCR_Sri PF10327.9 CBY20564.1 - 0.0079 15.4 0.5 0.015 14.5 0.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri DUF4061 PF13270.6 CBY20565.1 - 2.4e-06 27.8 0.0 3.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) Spindle_Spc25 PF08234.12 CBY20565.1 - 0.065 13.4 0.6 0.18 12.0 0.3 1.7 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 DUF948 PF06103.11 CBY20565.1 - 0.071 13.4 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Laps PF10169.9 CBY20566.1 - 1e-08 35.8 12.8 5.4e-08 33.5 12.8 1.9 1 1 0 1 1 1 1 Learning-associated protein CK2S PF15011.6 CBY20566.1 - 0.046 13.6 0.5 0.056 13.3 0.5 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate DUF2423 PF10338.9 CBY20566.1 - 0.081 13.2 11.5 0.55 10.5 11.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2423) Glyco_hydro_14 PF01373.17 CBY20566.1 - 0.12 11.3 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Pkinase PF00069.25 CBY20567.1 - 1.7e-68 230.9 0.0 2.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20567.1 - 1e-35 123.3 0.0 1.3e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CBY20567.1 - 6.9e-08 33.1 2.4 6.9e-08 33.1 2.4 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 CBY20567.1 - 2e-05 23.6 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY20567.1 - 0.00034 19.7 0.0 0.00053 19.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBY20567.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY20567.1 - 0.0014 18.0 0.0 0.0048 16.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CBY20567.1 - 0.012 15.3 0.4 2.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBY20567.1 - 0.016 15.1 0.1 0.043 13.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CBY20568.1 - 8.4e-59 199.1 0.0 1.1e-58 198.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20568.1 - 2.4e-29 102.4 0.0 3.7e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY20568.1 - 0.00054 19.4 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY20568.1 - 0.00079 18.5 0.1 0.001 18.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 CBY20568.1 - 0.004 17.8 0.1 0.004 17.8 0.1 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.14 CBY20568.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBY20568.1 - 0.012 15.3 0.1 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CBY20568.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CBY20568.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4586 PF15239.6 CBY20569.1 - 2.1e-104 350.0 17.2 2.3e-104 349.8 17.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) APG12 PF04110.13 CBY20570.1 - 1.8e-28 98.8 0.0 2e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 CBY20570.1 - 6.2e-05 23.1 0.0 6.6e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like VPS9 PF02204.18 CBY20571.1 - 4.7e-17 62.1 0.0 1.2e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-A20 PF01754.16 CBY20571.1 - 1.4e-09 37.7 7.1 1.4e-09 37.7 7.1 2.0 2 0 0 2 2 2 1 A20-like zinc finger DUF5601 PF18151.1 CBY20571.1 - 0.014 15.6 2.9 0.029 14.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) SGTA_dimer PF16546.5 CBY20571.1 - 0.025 14.4 0.1 0.18 11.6 0.0 2.4 2 0 0 2 2 2 0 Homodimerisation domain of SGTA WD40 PF00400.32 CBY20573.1 - 2.8e-36 122.9 7.8 1.5e-07 32.0 0.5 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20573.1 - 1.7e-15 57.1 1.7 0.002 18.4 0.0 5.8 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY20573.1 - 9e-09 34.7 4.1 0.26 10.2 0.0 4.2 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CBY20573.1 - 6.7e-06 24.9 0.1 0.033 12.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 CBY20573.1 - 1.9e-05 23.5 0.1 0.011 14.4 0.1 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CBY20573.1 - 8.1e-05 22.6 0.0 0.0003 20.7 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY20573.1 - 0.00033 20.1 0.3 0.013 14.8 0.1 2.5 3 0 0 3 3 3 1 WD40-like domain PD40 PF07676.12 CBY20573.1 - 0.015 15.2 1.8 10 6.2 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 CBY20573.1 - 0.017 13.5 0.0 0.034 12.5 0.0 1.4 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PHTB1_N PF14727.6 CBY20573.1 - 0.036 13.4 0.0 5.1 6.4 0.0 2.1 2 0 0 2 2 2 0 PTHB1 N-terminus CDC45 PF02724.14 CBY20574.1 - 1.1e-83 281.6 0.2 4.5e-51 173.9 1.3 2.0 1 1 1 2 2 2 2 CDC45-like protein HDC PF02329.16 CBY20574.1 - 0.098 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Histidine carboxylase PI chain CDC45 PF02724.14 CBY20575.1 - 4e-22 78.3 0.1 4.7e-22 78.1 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Mesd PF10185.9 CBY20575.1 - 0.028 14.3 0.0 0.18 11.7 0.0 1.9 1 1 1 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor Pkinase PF00069.25 CBY20576.1 - 1.6e-58 198.2 0.1 1.9e-58 197.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20576.1 - 6.1e-26 91.3 0.1 7.1e-26 91.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY20576.1 - 4.1e-06 26.3 0.0 6.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY20576.1 - 7.9e-06 26.0 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY20576.1 - 0.00019 20.4 0.0 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBY20576.1 - 0.00082 19.0 0.2 0.0013 18.3 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBY20576.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY20576.1 - 0.0064 15.5 0.2 0.012 14.5 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 CBY20576.1 - 0.0067 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.20 CBY20576.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 CBY20576.1 - 0.024 14.3 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF5446 PF17522.2 CBY20576.1 - 0.078 13.2 0.3 0.29 11.3 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Pox_ser-thr_kin PF05445.11 CBY20576.1 - 0.14 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase IQ PF00612.27 CBY20577.1 - 0.00037 20.0 0.1 0.0011 18.6 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Rimk_N PF18030.1 CBY20577.1 - 0.059 13.8 3.5 0.18 12.2 0.1 3.0 3 0 0 3 3 3 0 RimK PreATP-grasp domain DUF3584 PF12128.8 CBY20577.1 - 0.74 7.2 32.6 0.96 6.9 32.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Gaa1 PF04114.14 CBY20578.1 - 1.6e-54 185.8 2.6 9.3e-54 183.3 2.6 1.9 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component NIF PF03031.18 CBY20579.1 - 3.4e-52 176.3 0.1 4.3e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase OST3_OST6 PF04756.13 CBY20579.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Ribonuclease_3 PF00636.26 CBY20581.1 - 4.5e-39 133.3 0.3 6.7e-18 65.2 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CBY20581.1 - 2.3e-38 131.2 0.0 1.1e-18 67.6 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 CBY20581.1 - 2.5e-11 44.1 0.0 5.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif CBP_BcsR PF10945.8 CBY20581.1 - 0.012 15.1 0.7 0.4 10.2 0.0 2.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR PDZ PF00595.24 CBY20582.1 - 1.7e-79 262.2 10.9 8.2e-13 48.5 0.0 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 CBY20582.1 - 8.7e-58 192.0 9.5 4.8e-10 39.1 0.0 7.3 7 0 0 7 7 7 6 PDZ domain PDZ_2 PF13180.6 CBY20582.1 - 8.2e-28 96.6 3.5 3.2e-06 27.4 0.0 7.2 7 0 0 7 7 7 5 PDZ domain PVL_ORF50 PF07768.11 CBY20582.1 - 1.4 9.2 4.1 2.3 8.6 2.2 2.2 2 0 0 2 2 2 0 PVL ORF-50-like family HORMA PF02301.18 CBY20583.1 - 2e-20 73.3 2.7 2.7e-20 72.9 2.7 1.2 1 0 0 1 1 1 1 HORMA domain Sulfotransfer_3 PF13469.6 CBY20584.1 - 3.7e-27 96.1 0.0 7e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY20584.1 - 2.9e-10 40.1 0.3 6.5e-10 38.9 0.3 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 CBY20584.1 - 0.0086 15.9 0.0 0.029 14.2 0.0 1.9 2 1 0 2 2 2 1 Sulfotransferase domain Protocadherin PF08374.11 CBY20585.1 - 0.018 15.0 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Protocadherin UL45 PF05473.12 CBY20585.1 - 0.018 14.7 0.5 0.036 13.7 0.0 1.8 3 0 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like PEX11 PF05648.14 CBY20585.1 - 0.16 11.4 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF5383 PF17355.2 CBY20585.1 - 2.8 8.3 5.9 15 6.0 0.1 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5383) ATP-synt_F6 PF05511.11 CBY20587.1 - 1.6e-16 60.5 0.0 2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 ATP_sub_h PF10775.9 CBY20587.1 - 0.012 15.5 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase complex subunit h Neur_chan_LBD PF02931.23 CBY20588.1 - 1.5e-45 155.3 0.8 2.4e-45 154.6 0.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY20588.1 - 1.2e-28 100.8 2.5 3.7e-25 89.4 0.5 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HHA PF05321.11 CBY20590.1 - 0.13 12.6 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Haemolysin expression modulating protein zf-C4 PF00105.18 CBY20591.1 - 5.7e-18 65.1 6.9 6.8e-18 64.9 6.9 1.1 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY20592.1 - 4.3e-09 36.3 5.2 8.2e-09 35.3 3.7 2.2 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Peptidase_S74 PF13884.6 CBY20592.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Chaperone of endosialidase Ank_5 PF13857.6 CBY20593.1 - 6.3e-07 29.5 0.1 0.011 16.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY20593.1 - 0.00061 20.3 0.0 0.21 12.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Sina PF03145.16 CBY20594.1 - 1.7e-82 276.3 1.3 2.3e-82 275.8 1.3 1.2 1 0 0 1 1 1 1 Seven in absentia protein family Prok-RING_4 PF14447.6 CBY20594.1 - 1.6 8.6 12.4 37 4.3 12.7 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 UPF0449 PF15136.6 CBY20596.1 - 0.0014 19.1 2.2 0.0021 18.5 2.2 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0449 p47_phox_C PF08944.11 CBY20596.1 - 0.042 13.3 0.2 0.074 12.5 0.2 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Transglut_i_TM PF14400.6 CBY20596.1 - 0.082 13.0 0.4 0.22 11.6 0.4 1.7 1 1 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices Peptidase_C1 PF00112.23 CBY20597.1 - 6.1e-74 248.8 1.7 8.1e-74 248.4 1.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY20597.1 - 1.3e-09 38.4 2.9 2.7e-09 37.3 2.9 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY20597.1 - 1.4e-05 24.1 0.3 0.038 12.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 CBY20597.1 - 0.0069 16.3 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide SAP PF02037.27 CBY20599.1 - 3.3e-06 26.7 0.4 6.7e-06 25.7 0.4 1.6 1 0 0 1 1 1 1 SAP domain zf-C4H2 PF10146.9 CBY20599.1 - 1 9.6 18.5 3.6 7.9 18.0 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4407 PF14362.6 CBY20599.1 - 1.6 8.0 18.1 3.6 6.8 18.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 CBY20599.1 - 2.4 6.6 5.0 3.6 6.0 5.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1451 PF07295.11 CBY20599.1 - 4.2 7.4 11.2 0.16 12.0 3.3 2.4 1 1 0 2 2 2 0 Zinc-ribbon containing domain DUF1664 PF07889.12 CBY20599.1 - 5.9 6.9 12.3 0.43 10.6 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Plasmid_RAQPRD PF09686.10 CBY20599.1 - 6.2 7.1 10.2 0.24 11.7 2.5 2.4 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) IQ PF00612.27 CBY20601.1 - 3.1e-05 23.4 7.6 0.0043 16.7 0.0 3.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif DUF896 PF05979.12 CBY20601.1 - 0.00039 20.2 0.3 0.0028 17.5 0.0 2.6 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF896) DUF917 PF06032.12 CBY20601.1 - 0.049 12.5 0.1 0.073 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF917) HeLo PF14479.6 CBY20601.1 - 0.45 10.3 8.8 0.07 12.9 2.3 2.1 1 1 0 2 2 2 0 Prion-inhibition and propagation Pkinase PF00069.25 CBY20602.1 - 8.6e-56 189.2 0.0 3.4e-54 184.0 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 CBY20602.1 - 1.1e-41 140.8 0.3 1e-21 76.8 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY20602.1 - 2.9e-26 92.3 0.0 4.1e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY20602.1 - 0.0056 15.5 0.1 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CBY20602.1 - 0.0084 15.5 0.0 0.056 12.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBY20602.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MRP-S28 PF10213.9 CBY20603.1 - 1.3e-06 28.9 0.0 1.1e-05 25.9 0.0 2.4 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein DnaJ PF00226.31 CBY20604.1 - 1.1e-21 76.7 0.1 2.6e-21 75.5 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 CBY20604.1 - 1.7e-09 37.6 0.0 1.3e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CBY20604.1 - 5.6e-05 23.5 0.4 0.0033 17.8 0.1 3.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 CBY20604.1 - 0.0008 19.4 1.4 0.38 10.6 0.0 3.5 3 0 0 3 3 3 1 Thioredoxin-like domain Glutaredoxin PF00462.24 CBY20604.1 - 0.0093 16.2 0.1 0.046 13.9 0.1 2.3 1 0 0 1 1 1 1 Glutaredoxin SGT1 PF07093.11 CBY20605.1 - 1.1e-98 331.3 3.1 4.8e-98 329.1 3.1 1.8 1 1 0 1 1 1 1 SGT1 protein Read-through PF16814.5 CBY20605.1 - 0.085 12.6 0.3 0.39 10.5 0.1 2.0 1 1 1 2 2 2 0 Read-through domain DNA_pol_E_B PF04042.16 CBY20606.1 - 5.4e-30 104.3 0.7 7.1e-30 103.9 0.7 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 CBY20606.1 - 0.0056 16.7 0.6 0.034 14.1 0.6 2.0 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Img2 PF05046.14 CBY20607.1 - 4.1e-08 33.4 0.0 1.2e-06 28.7 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial large subunit ribosomal protein (Img2) zf-met PF12874.7 CBY20608.1 - 0.1 13.0 3.6 0.34 11.4 3.6 1.9 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY20608.1 - 0.13 12.6 6.4 0.36 11.2 6.4 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2072 PF09845.9 CBY20609.1 - 0.24 11.7 2.8 8.9 6.6 0.1 2.4 2 0 0 2 2 2 0 Zn-ribbon containing protein Sad1_UNC PF07738.13 CBY20610.1 - 1.4e-33 115.7 0.0 2.7e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Lip_prot_lig_C PF10437.9 CBY20610.1 - 0.15 12.1 0.2 0.46 10.5 0.1 1.9 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus V_ATPase_I PF01496.19 CBY20612.1 - 0 1030.1 0.0 0 1029.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family YojJ PF10372.9 CBY20612.1 - 0.1 12.7 0.8 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Wzz PF02706.15 CBY20612.1 - 0.11 12.8 0.1 0.52 10.6 0.1 2.1 1 0 0 1 1 1 0 Chain length determinant protein rRNA_proc-arch PF13234.6 CBY20612.1 - 0.13 12.2 1.9 0.27 11.1 1.9 1.4 1 0 0 1 1 1 0 rRNA-processing arch domain WDCP PF15390.6 CBY20612.1 - 0.36 9.2 1.1 0.59 8.5 1.1 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DegS PF05384.11 CBY20612.1 - 0.38 10.2 7.6 6.6 6.2 0.2 3.2 3 0 0 3 3 3 0 Sensor protein DegS DUF948 PF06103.11 CBY20612.1 - 0.71 10.2 2.9 3.4 8.0 0.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 CBY20612.1 - 8.1 6.8 9.1 54 4.2 9.1 2.0 1 1 0 1 1 1 0 Fez1 Occludin_ELL PF07303.13 CBY20612.1 - 8.5 7.2 6.4 47 4.8 0.8 3.4 3 0 0 3 3 3 0 Occludin homology domain DUF2854 PF11016.8 CBY20613.1 - 0.00039 20.3 0.7 0.00088 19.2 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) RRM_1 PF00076.22 CBY20613.1 - 0.0018 18.1 0.0 1.6 8.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY20613.1 - 0.0033 17.0 0.1 0.011 15.4 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoU_sub_bind PF08032.12 CBY20614.1 - 0.3 11.4 2.0 31 5.0 0.0 3.3 2 1 1 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding O-FucT PF10250.9 CBY20615.1 - 1.6e-08 34.6 0.1 4.7e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Mucin PF01456.17 CBY20616.1 - 0.42 10.6 10.2 0.56 10.2 10.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 CBY20616.1 - 5.7 5.0 9.5 7.8 4.6 9.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tubulin PF00091.25 CBY20617.1 - 5.6e-68 229.0 0.0 7.4e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY20617.1 - 1.7e-47 160.7 0.0 2.8e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY20617.1 - 0.0016 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Lectin_C PF00059.21 CBY20618.1 - 2.3e-16 60.5 1.1 6.4e-08 33.3 0.1 3.2 3 0 0 3 3 3 2 Lectin C-type domain DUF3877 PF12993.7 CBY20618.1 - 0.045 13.6 0.6 0.2 11.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) FliJ PF02050.16 CBY20618.1 - 0.39 11.0 6.5 13 6.0 0.1 3.8 3 0 0 3 3 3 0 Flagellar FliJ protein Phage_TAC_10 PF10963.8 CBY20618.1 - 1 9.6 3.6 40 4.5 0.4 3.1 3 0 0 3 3 3 0 Phage tail assembly chaperone DUF4200 PF13863.6 CBY20618.1 - 1.7 9.0 14.3 0.1 13.0 1.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) Tubulin PF00091.25 CBY20619.1 - 2.2e-68 230.3 0.0 3e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY20619.1 - 1.8e-52 176.8 0.0 2.9e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY20619.1 - 0.00036 20.3 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain SEP PF08059.13 CBY20622.1 - 8.1e-22 77.6 0.1 3.5e-21 75.5 0.1 2.1 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 CBY20622.1 - 1.6e-13 50.2 0.5 3e-13 49.3 0.5 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 CBY20622.1 - 1.5e-10 41.1 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 UBX domain zf_C2H2_ZHX PF18387.1 CBY20623.1 - 0.0002 20.9 5.8 0.3 10.8 0.2 3.2 2 1 1 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 CBY20623.1 - 0.0004 20.7 7.0 0.45 10.9 0.2 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 CBY20623.1 - 0.0017 18.6 9.1 0.17 12.2 0.2 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CBY20623.1 - 0.023 14.4 16.8 0.62 9.9 0.7 4.4 4 2 1 5 5 5 0 C2H2-type zinc-finger domain AKAP95 PF04988.12 CBY20623.1 - 0.057 13.6 12.0 0.35 11.1 0.3 3.2 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF4666 PF15697.5 CBY20623.1 - 0.13 13.0 1.1 0.3 11.8 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) zf-C2H2_4 PF13894.6 CBY20623.1 - 0.3 12.0 18.0 1 10.4 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger OrsD PF12013.8 CBY20623.1 - 0.32 11.5 5.6 1 9.8 0.1 2.9 2 2 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 CBY20623.1 - 6.5 7.4 9.3 16 6.2 0.6 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type SET PF00856.28 CBY20626.1 - 5.5e-14 52.9 6.7 9.3e-14 52.2 0.0 3.4 2 2 0 2 2 2 1 SET domain DUF3122 PF11320.8 CBY20627.1 - 0.081 13.0 0.3 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) DUF5387 PF17361.2 CBY20627.1 - 0.14 11.8 1.3 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5387) DUF1664 PF07889.12 CBY20627.1 - 0.36 10.9 3.9 2.1 8.4 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BST2 PF16716.5 CBY20627.1 - 3.7 8.2 5.5 2.8 8.6 0.4 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Methyltransf_31 PF13847.6 CBY20628.1 - 7.3e-19 68.1 0.3 1.6e-18 67.0 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY20628.1 - 3.7e-15 56.4 0.1 7.1e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY20628.1 - 2.2e-12 47.5 0.1 5e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY20628.1 - 2.3e-10 40.6 0.0 3.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY20628.1 - 4.2e-10 40.3 0.0 8.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY20628.1 - 7.9e-07 28.6 0.0 1.5e-06 27.7 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CBY20628.1 - 8.9e-07 28.4 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 CBY20628.1 - 4.1e-06 26.5 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 CBY20628.1 - 1.1e-05 25.2 0.0 3.7e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Nodulation protein S (NodS) PrmA PF06325.13 CBY20628.1 - 0.0003 20.3 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CBY20628.1 - 0.0017 18.3 0.0 0.0033 17.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CBY20628.1 - 0.0033 18.4 0.0 0.0071 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CBY20628.1 - 0.0063 15.7 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.20 CBY20628.1 - 0.0083 15.2 0.0 0.02 14.0 0.0 1.6 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 CBY20628.1 - 0.0096 15.5 0.0 0.026 14.1 0.0 1.6 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.17 CBY20628.1 - 0.032 13.7 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Dimerisation2 PF16864.5 CBY20628.1 - 0.04 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain PCMT PF01135.19 CBY20628.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_3 PF08777.11 CBY20629.1 - 1.4e-16 60.4 0.5 1.4e-16 60.4 0.5 2.4 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 CBY20629.1 - 2.7e-05 23.9 0.0 5.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY20629.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CBY20630.1 - 2.1e-07 30.6 0.0 3.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY20630.1 - 0.0024 18.0 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 CBY20630.1 - 0.069 13.4 0.1 0.37 11.0 0.1 2.0 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter GST_N_3 PF13417.6 CBY20630.1 - 0.11 13.0 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF968 PF06147.11 CBY20630.1 - 0.22 11.8 0.7 0.39 10.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF968) UAA PF08449.11 CBY20631.1 - 2e-56 191.4 13.1 2.5e-56 191.1 13.1 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBY20631.1 - 0.00087 19.5 18.0 0.0068 16.6 11.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CBY20631.1 - 0.018 14.4 7.4 0.034 13.5 7.4 1.4 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF2070 PF09843.9 CBY20631.1 - 0.026 12.8 6.5 0.03 12.7 6.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Dicty_CTDC PF00526.18 CBY20632.1 - 0.049 13.5 3.6 9.8 6.2 1.2 3.3 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat UAA PF08449.11 CBY20633.1 - 0.00034 19.9 0.0 0.00044 19.6 0.0 1.1 1 0 0 1 1 1 1 UAA transporter family Rtf2 PF04641.12 CBY20634.1 - 1.5e-34 119.6 29.2 1.2e-32 113.4 29.2 3.1 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 CBY20634.1 - 0.003 17.5 1.5 0.0066 16.4 1.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY20634.1 - 0.01 15.6 2.4 0.019 14.8 2.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 CBY20634.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Ndc1_Nup PF09531.10 CBY20634.1 - 0.6 8.7 8.1 0.97 8.0 8.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup adh_short PF00106.25 CBY20635.1 - 6.8e-39 133.4 0.1 9.1e-39 132.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY20635.1 - 2.3e-26 92.8 0.1 6.1e-26 91.4 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY20635.1 - 1.2e-05 25.3 0.6 6.2e-05 23.0 0.6 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY20635.1 - 6.3e-05 22.5 0.0 0.00093 18.7 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBY20635.1 - 9e-05 22.4 0.0 0.00029 20.8 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CBY20635.1 - 0.00026 20.1 0.1 0.00056 19.0 0.1 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Rtf2 PF04641.12 CBY20636.1 - 4.6e-32 111.4 3.0 6e-32 111.0 2.4 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger Rtf2 PF04641.12 CBY20637.1 - 0.064 12.6 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Tweety PF04906.13 CBY20638.1 - 0.03 13.0 0.4 0.04 12.6 0.4 1.1 1 0 0 1 1 1 0 Tweety Shisa PF13908.6 CBY20638.1 - 0.073 13.3 0.1 0.076 13.3 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.6 CBY20638.1 - 0.2 12.0 1.8 0.38 11.1 1.8 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal EF_TS PF00889.19 CBY20639.1 - 0.027 14.1 1.2 0.42 10.2 0.5 2.0 1 1 1 2 2 2 0 Elongation factor TS Stathmin PF00836.19 CBY20639.1 - 0.16 12.0 6.8 0.23 11.4 6.8 1.2 1 0 0 1 1 1 0 Stathmin family DUF2681 PF10883.8 CBY20639.1 - 0.3 11.5 3.4 0.44 11.0 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) EF-G-binding_N PF07299.11 CBY20639.1 - 0.48 11.0 3.2 1.3 9.6 1.1 2.1 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal ZapB PF06005.12 CBY20640.1 - 0.00099 19.5 19.1 0.024 15.1 3.5 3.2 3 0 0 3 3 3 1 Cell division protein ZapB UPF0242 PF06785.11 CBY20640.1 - 0.002 18.3 13.5 0.021 14.9 0.5 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 CBY20640.1 - 0.015 14.3 4.1 0.017 14.1 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Lebercilin PF15619.6 CBY20640.1 - 0.019 14.6 21.0 0.11 12.1 8.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease IFP_35_N PF07334.13 CBY20640.1 - 0.028 14.5 0.3 0.028 14.5 0.3 3.2 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF848 PF05852.11 CBY20640.1 - 0.048 13.8 0.2 0.048 13.8 0.2 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.15 CBY20640.1 - 0.048 13.4 17.8 0.36 10.6 1.6 3.6 3 0 0 3 3 3 0 Septum formation initiator APG6_N PF17675.1 CBY20640.1 - 0.069 13.7 17.3 0.15 12.6 10.7 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region Siah-Interact_N PF09032.11 CBY20640.1 - 0.072 13.4 0.8 0.072 13.4 0.8 2.8 2 1 0 2 2 2 0 Siah interacting protein, N terminal CENP-F_leu_zip PF10473.9 CBY20640.1 - 0.073 13.1 17.1 0.5 10.4 1.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 CBY20640.1 - 0.076 13.2 7.7 0.18 12.0 0.5 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ax_dynein_light PF10211.9 CBY20640.1 - 0.09 12.7 17.6 0.078 12.9 7.7 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain DUF1192 PF06698.11 CBY20640.1 - 0.12 12.4 3.3 0.15 12.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Fungal_TACC PF12709.7 CBY20640.1 - 0.14 12.6 15.7 0.26 11.8 2.2 3.2 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins UPF0449 PF15136.6 CBY20640.1 - 0.16 12.5 9.6 0.5 10.9 4.0 2.9 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 FapA PF03961.13 CBY20640.1 - 0.16 10.5 12.1 0.26 9.9 3.4 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A FRG PF08867.11 CBY20640.1 - 0.2 12.6 7.3 0.77 10.7 0.5 3.0 2 1 1 3 3 3 0 FRG domain bZIP_1 PF00170.21 CBY20640.1 - 0.24 11.5 20.0 0.077 13.1 2.2 3.4 3 0 0 3 3 3 0 bZIP transcription factor DUF1664 PF07889.12 CBY20640.1 - 0.28 11.2 10.1 1.5 8.9 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CBY20640.1 - 0.32 11.4 9.5 7.3 7.1 0.7 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4446 PF14584.6 CBY20640.1 - 0.46 10.5 10.0 1.8 8.5 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) NRBF2 PF08961.10 CBY20640.1 - 0.95 9.0 12.1 0.027 14.1 1.7 2.7 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Mto2_bdg PF12808.7 CBY20640.1 - 0.99 9.7 13.1 0.69 10.3 0.7 3.3 3 1 1 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4094 PF13334.6 CBY20640.1 - 1.1 9.8 4.6 1.4 9.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF5082 PF16888.5 CBY20640.1 - 1.1 9.5 13.7 0.69 10.2 2.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) HMMR_C PF15908.5 CBY20640.1 - 1.4 9.2 15.3 0.09 13.0 6.7 2.8 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal YabA PF06156.13 CBY20640.1 - 3.1 8.5 16.9 0.61 10.7 3.8 3.2 2 1 1 3 3 3 0 Initiation control protein YabA DivIVA PF05103.13 CBY20640.1 - 3.3 7.8 16.5 0.52 10.4 3.8 3.1 2 1 1 3 3 3 0 DivIVA protein DUF4407 PF14362.6 CBY20640.1 - 4.4 6.6 10.0 9.2 5.5 8.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 CBY20640.1 - 6.1 7.1 20.0 3.6 7.9 2.6 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Csm1_N PF18504.1 CBY20640.1 - 9 6.7 16.6 0.11 12.9 2.5 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF724 PF05266.14 CBY20640.1 - 9.9 5.9 16.5 7.1 6.4 6.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF724) LRR_8 PF13855.6 CBY20641.1 - 1.6e-76 252.0 44.7 7.1e-17 60.9 0.2 6.9 3 2 6 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 CBY20641.1 - 1.7e-27 95.0 38.2 2.6e-06 27.7 0.8 9.1 4 2 5 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY20641.1 - 6.5e-26 90.8 3.7 1.8e-13 50.6 0.0 2.8 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) I-set PF07679.16 CBY20641.1 - 3.3e-16 59.1 0.0 7.3e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY20641.1 - 4.2e-14 52.9 0.6 1.6e-13 51.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 CBY20641.1 - 1.5e-11 43.2 23.0 3.6 8.5 0.1 12.0 11 1 0 11 11 11 3 Leucine Rich Repeat LRR_9 PF14580.6 CBY20641.1 - 4e-11 42.7 23.8 0.0047 16.5 1.0 4.2 2 2 2 4 4 4 4 Leucine-rich repeat LRRNT PF01462.18 CBY20641.1 - 6.9e-09 35.1 13.0 5.3e-06 26.0 1.1 2.9 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain Ig_2 PF13895.6 CBY20641.1 - 5.9e-08 32.9 0.6 2e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CBY20641.1 - 1.3e-07 31.7 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CBY20641.1 - 6.6e-07 29.5 0.2 3e-05 24.1 0.1 3.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain DUF4252 PF14060.6 CBY20641.1 - 0.071 13.0 2.5 6.6 6.6 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4252) TPR_21 PF09976.9 CBY20641.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain LRR_6 PF13516.6 CBY20641.1 - 0.32 11.2 0.1 0.32 11.2 0.1 9.4 11 0 0 11 11 10 0 Leucine Rich repeat DUF4461 PF14688.6 CBY20642.1 - 6.5e-12 45.9 0.1 7.5e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) Rcd1 PF04078.13 CBY20643.1 - 5.8e-122 406.0 0.6 6.8e-122 405.7 0.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Gelsolin PF00626.22 CBY20643.1 - 0.034 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Gelsolin repeat Ribosomal_S5 PF00333.20 CBY20644.1 - 2e-29 101.3 1.3 3.9e-29 100.4 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CBY20644.1 - 2.4e-26 91.0 0.0 3.8e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain HECT_2 PF09814.9 CBY20645.1 - 7.1e-06 25.1 3.4 0.014 14.2 0.3 2.3 2 1 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Tudor_4 PF18358.1 CBY20645.1 - 0.14 11.8 0.0 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain DUF1043 PF06295.12 CBY20646.1 - 0.013 15.5 0.5 0.024 14.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FadA PF09403.10 CBY20646.1 - 0.022 15.2 6.1 0.057 13.9 6.1 1.6 1 0 0 1 1 1 0 Adhesion protein FadA Abhydrolase_1 PF00561.20 CBY20647.1 - 1.8e-12 47.4 0.4 5.3e-10 39.4 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBY20647.1 - 3.1e-12 46.3 0.0 4.5e-09 35.9 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBY20647.1 - 4.2e-08 34.1 0.0 6.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY20647.1 - 0.003 17.7 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF818 PF05677.12 CBY20647.1 - 0.0048 15.9 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DUF829 PF05705.14 CBY20647.1 - 0.071 13.0 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) A_deamin PF02137.18 CBY20648.1 - 6.7e-95 318.3 0.0 9.6e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 CBY20648.1 - 3e-08 34.2 0.0 0.014 16.1 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ge1_WD40 PF16529.5 CBY20649.1 - 1.8e-77 260.5 0.3 3.2e-77 259.7 0.3 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 CBY20649.1 - 1.2e-07 32.3 2.3 1.1e-05 26.1 0.2 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.6 CBY20649.1 - 0.00087 19.7 0.1 0.0028 18.1 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CBY20649.1 - 0.0081 16.2 0.5 0.025 14.5 0.1 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Subtilosin_A PF11420.8 CBY20649.1 - 0.033 14.1 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Bacteriocin subtilosin A TetR_C_37 PF18665.1 CBY20649.1 - 0.071 13.7 0.4 0.67 10.6 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF2852 PF11014.8 CBY20650.1 - 0.041 14.1 0.5 1 9.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Elongin_A PF06881.11 CBY20651.1 - 1.1e-10 41.9 0.5 1.1e-10 41.9 0.5 5.1 4 2 0 4 4 4 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2816 PF10992.8 CBY20651.1 - 0.084 12.8 1.2 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2816) NIF PF03031.18 CBY20652.1 - 2.3e-49 167.1 0.1 2.9e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SSXRD PF09514.10 CBY20652.1 - 0.045 13.3 0.5 0.084 12.5 0.5 1.5 1 0 0 1 1 1 0 SSXRD motif DUF4530 PF15039.6 CBY20653.1 - 0.0033 17.6 0.5 0.0053 16.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) Terminase_4 PF05119.12 CBY20653.1 - 0.032 14.7 0.6 0.067 13.6 0.3 1.6 2 0 0 2 2 2 0 Phage terminase, small subunit PPV_E2_N PF00508.17 CBY20653.1 - 0.08 12.3 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 E2 (early) protein, N terminal DUF4950 PF16308.5 CBY20653.1 - 0.084 12.9 0.4 0.084 12.9 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4950) CENP-H PF05837.12 CBY20653.1 - 0.099 13.1 5.5 0.19 12.2 5.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Peptidase_C48 PF02902.19 CBY20654.1 - 4.2e-08 33.3 10.5 7.1e-07 29.3 0.4 3.3 4 1 1 5 5 5 2 Ulp1 protease family, C-terminal catalytic domain SIR2 PF02146.17 CBY20655.1 - 2.7e-24 86.1 1.0 1e-17 64.7 0.0 2.5 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 CBY20655.1 - 9.6e-05 22.1 0.0 0.51 10.1 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Carb_anhydrase PF00194.21 CBY20656.1 - 1.8e-75 253.7 0.0 2.1e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MTH865 PF07747.11 CBY20656.1 - 0.015 15.1 0.2 0.033 14.0 0.1 1.6 2 0 0 2 2 2 0 MTH865-like family Rav1p_C PF12234.8 CBY20658.1 - 4.5e-52 177.4 0.7 1.5e-51 175.6 0.2 2.1 2 1 0 2 2 2 1 RAVE protein 1 C terminal ANAPC4_WD40 PF12894.7 CBY20658.1 - 6.5e-10 39.2 0.4 0.0012 19.1 0.0 4.8 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY20658.1 - 1.2e-06 29.1 15.0 0.32 11.9 0.0 7.8 8 0 0 8 8 8 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY20658.1 - 0.024 13.6 0.1 0.24 10.3 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 CBY20658.1 - 0.23 11.2 1.2 28 4.4 0.0 3.1 4 0 0 4 4 4 0 Lipoprotein LpqB beta-propeller domain Thymidylat_synt PF00303.19 CBY20659.1 - 4.5e-118 393.2 0.0 5.1e-118 393.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HMGL-like PF00682.19 CBY20660.1 - 4.2e-53 180.6 0.0 4.8e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 HMGL-like HisKA_3 PF07730.13 CBY20660.1 - 0.43 11.1 1.5 0.58 10.7 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase RRM_1 PF00076.22 CBY20661.1 - 6.6e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOC3p PF07540.11 CBY20662.1 - 8.6e-23 80.6 0.3 8.6e-23 80.6 0.3 2.6 2 0 0 2 2 2 1 Nucleolar complex-associated protein Linker_histone PF00538.19 CBY20662.1 - 4.6 7.7 8.0 24 5.4 4.5 2.9 2 0 0 2 2 2 0 linker histone H1 and H5 family CBF PF03914.17 CBY20662.1 - 5.6 7.0 8.1 0.68 10.0 0.5 3.1 3 1 0 3 3 3 0 CBF/Mak21 family Nucleoporin_N PF08801.11 CBY20663.1 - 1.4e-74 251.5 0.0 2e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CBY20663.1 - 4.2e-19 68.7 0.6 6.8e-19 68.0 0.6 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DIPSY PF11763.8 CBY20663.1 - 0.16 12.1 0.0 0.49 10.6 0.0 1.7 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Ribosomal_L22 PF00237.19 CBY20664.1 - 2.7e-40 136.8 0.1 4.6e-40 136.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L2_C PF03947.18 CBY20665.1 - 3.2e-43 146.9 3.5 5.1e-43 146.3 3.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBY20665.1 - 1.9e-15 56.6 0.2 5e-15 55.2 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain GON PF08685.11 CBY20666.1 - 2.4e-63 213.6 0.0 2.4e-63 213.6 0.0 2.6 2 0 0 2 2 2 1 GON domain TSP_1 PF00090.19 CBY20666.1 - 5.3e-25 87.4 176.1 5.3e-09 36.2 10.9 12.9 13 0 0 13 13 13 9 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 CBY20666.1 - 1.5e-13 51.1 9.0 1.5e-13 51.1 9.0 8.4 8 4 2 10 10 10 2 ADAM cysteine-rich domain Reprolysin PF01421.19 CBY20666.1 - 2.3e-11 44.0 0.5 2.3e-11 44.0 0.5 1.9 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 CBY20666.1 - 2.1e-06 28.3 0.0 5.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CBY20666.1 - 1.1e-05 25.7 0.1 1.1e-05 25.7 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 ADAM_spacer1 PF05986.14 CBY20666.1 - 6.1e-05 23.0 0.1 0.00028 20.9 0.1 2.0 2 0 0 2 2 2 1 ADAM-TS Spacer 1 Reprolysin_2 PF13574.6 CBY20666.1 - 0.0016 18.4 0.2 0.0054 16.7 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY20666.1 - 0.0016 18.1 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Trypsin PF00089.26 CBY20667.1 - 4.8e-23 82.1 0.3 5.7e-23 81.9 0.3 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY20667.1 - 0.15 12.5 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Frizzled PF01534.17 CBY20668.1 - 6.5e-50 170.0 16.1 9.1e-50 169.5 16.1 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CBY20668.1 - 1.2e-19 70.9 0.3 2.6e-19 69.9 0.3 1.6 1 0 0 1 1 1 1 Fz domain Motile_Sperm PF00635.26 CBY20669.1 - 2.7e-27 94.8 0.4 5.6e-27 93.8 0.4 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TRAM_LAG1_CLN8 PF03798.16 CBY20670.1 - 2.8e-15 56.6 18.2 3.7e-15 56.2 18.2 1.2 1 0 0 1 1 1 1 TLC domain PEN-2 PF10251.9 CBY20670.1 - 2.2 8.7 5.5 6.6 7.2 0.1 2.9 2 1 1 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Calsarcin PF05556.11 CBY20671.1 - 0.0046 16.5 0.1 0.0097 15.5 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-binding protein (Calsarcin) zf-C2H2 PF00096.26 CBY20672.1 - 4.3e-15 55.2 19.7 6.4e-05 23.2 2.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY20672.1 - 2.5e-10 40.3 10.2 5.5e-07 29.7 1.9 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY20672.1 - 1.6e-08 34.7 18.6 0.0013 19.4 2.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 CBY20672.1 - 0.00047 20.7 8.4 0.036 14.7 0.8 2.8 2 1 1 3 3 3 2 FOXP coiled-coil domain Ogr_Delta PF04606.12 CBY20672.1 - 0.0054 16.7 1.2 0.072 13.1 0.3 2.6 1 1 1 2 2 2 1 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 CBY20672.1 - 0.079 13.3 3.9 1.1 9.7 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY20672.1 - 0.083 12.9 1.1 0.083 12.9 1.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBY20672.1 - 1.9 8.2 9.6 0.34 10.6 0.9 3.0 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 CBY20672.1 - 2.2 8.8 6.2 0.99 9.9 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type EF-hand_1 PF00036.32 CBY20674.1 - 1.8e-17 61.5 13.9 0.0002 20.7 0.0 6.5 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.6 CBY20674.1 - 3.6e-17 60.7 12.7 0.0031 17.3 0.0 6.7 7 0 0 7 7 7 5 EF-hand domain EF-hand_7 PF13499.6 CBY20674.1 - 8.3e-15 55.0 21.1 5.5e-07 30.0 0.6 5.0 1 1 6 7 7 7 7 EF-hand domain pair EF-hand_5 PF13202.6 CBY20674.1 - 2.8e-13 48.7 20.5 0.0001 21.6 0.3 6.8 7 0 0 7 7 7 4 EF hand SPARC_Ca_bdg PF10591.9 CBY20674.1 - 3.6e-05 24.1 15.3 0.087 13.2 1.0 3.9 2 1 2 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CBY20674.1 - 0.00054 19.8 0.4 0.56 10.1 0.1 4.1 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 CBY20674.1 - 0.0031 17.3 17.0 0.2 11.5 0.1 5.4 6 1 0 6 6 6 3 EF-hand domain pair DUF1707 PF08044.11 CBY20674.1 - 0.065 13.3 0.3 9.1 6.4 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) HLH PF00010.26 CBY20675.1 - 9.5e-12 44.7 0.7 1.9e-11 43.7 0.2 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RCC1 PF00415.18 CBY20677.1 - 6.6e-28 97.1 2.9 5.4e-06 26.9 0.0 7.8 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY20677.1 - 4.8e-17 61.3 18.9 0.0015 18.2 0.2 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Methyltranf_PUA PF13636.6 CBY20677.1 - 0.087 12.8 0.1 12 6.0 0.1 2.8 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF JUPITER PF17054.5 CBY20678.1 - 4.9e-05 23.0 1.4 0.00029 20.4 0.2 2.0 2 0 0 2 2 2 2 Microtubule-Associated protein Jupiter Amidase PF01425.21 CBY20679.1 - 4.7e-73 246.7 0.0 1.6e-72 245.0 0.0 1.7 1 1 0 1 1 1 1 Amidase AAA PF00004.29 CBY20680.1 - 1.8e-40 138.4 0.0 4.2e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBY20680.1 - 1.9e-19 69.3 0.2 4.2e-19 68.3 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CBY20680.1 - 6.4e-10 38.7 0.3 1.8e-09 37.2 0.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBY20680.1 - 2.4e-05 24.5 0.0 5.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBY20680.1 - 5.5e-05 23.6 0.2 0.0072 16.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBY20680.1 - 0.0001 22.3 0.1 0.00068 19.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY20680.1 - 0.0012 19.1 0.5 0.1 12.9 0.1 2.4 1 1 0 2 2 2 1 AAA domain PhoH PF02562.16 CBY20680.1 - 0.0024 17.4 0.1 0.024 14.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 CBY20680.1 - 0.0042 16.5 0.2 0.031 13.7 0.1 2.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CBY20680.1 - 0.0055 16.5 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CBY20680.1 - 0.0073 15.5 0.0 0.021 14.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 CBY20680.1 - 0.0093 16.1 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY20680.1 - 0.011 15.4 0.4 0.038 13.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBY20680.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CBY20680.1 - 0.032 14.0 1.2 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CBY20680.1 - 0.062 12.6 0.3 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 KaiC DUF1640 PF07798.11 CBY20680.1 - 0.095 12.7 1.0 0.17 11.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Sigma54_activat PF00158.26 CBY20680.1 - 0.11 12.2 0.2 0.69 9.6 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 CBY20680.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 CBY20680.1 - 0.17 11.4 0.3 0.79 9.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain DIX PF00778.17 CBY20681.1 - 1.2e-07 31.5 0.0 5e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 DIX domain Axin_b-cat_bind PF08833.10 CBY20681.1 - 0.0054 16.8 0.3 0.018 15.1 0.3 1.9 1 0 0 1 1 1 1 Axin beta-catenin binding domain MtlR PF05068.12 CBY20681.1 - 0.25 11.3 0.7 3.9 7.4 0.0 2.5 3 0 0 3 3 3 0 Mannitol repressor PGAP1 PF07819.13 CBY20682.1 - 2.3e-40 138.7 0.0 3.8e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 CBY20682.1 - 4.8e-05 23.0 0.0 9.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 CBY20682.1 - 5.5e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 CBY20682.1 - 6.8e-05 22.8 0.0 9.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 CBY20682.1 - 6.9e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 CBY20682.1 - 0.00051 20.2 0.0 0.00092 19.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 CBY20682.1 - 0.0013 19.4 0.0 0.002 18.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 CBY20682.1 - 0.0013 18.1 0.0 0.035 13.4 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 CBY20682.1 - 0.0044 16.5 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CBY20682.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 CBY20682.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 CBY20682.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_8 PF06259.12 CBY20682.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S9 PF00326.21 CBY20682.1 - 0.054 13.0 0.3 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family YjbF PF11102.8 CBY20682.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF BHD_1 PF10403.9 CBY20683.1 - 0.014 15.2 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 ERO1 PF04137.15 CBY20684.1 - 6.1 5.9 9.3 5.5 6.1 3.4 2.2 2 0 0 2 2 2 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF2828 PF11443.8 CBY20684.1 - 8.6 4.3 13.0 0.072 11.2 5.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Guanylate_kin PF00625.21 CBY20685.1 - 4.3e-30 104.7 0.1 1.3e-29 103.2 0.1 1.8 1 1 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.28 CBY20685.1 - 0.034 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 SH3 domain CLPTM1 PF05602.12 CBY20686.1 - 5.8e-134 447.3 1.2 7.3e-134 447.0 1.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CBY20686.1 - 0.19 11.5 0.1 0.19 11.5 0.1 3.0 3 0 0 3 3 3 0 PQ loop repeat zf-C2H2_4 PF13894.6 CBY20687.1 - 3.6e-09 36.7 72.3 0.027 15.3 1.0 11.9 11 2 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY20687.1 - 0.0048 16.6 15.2 0.25 11.2 0.8 4.4 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 CBY20687.1 - 0.0069 16.8 0.8 0.0069 16.8 0.8 11.7 11 1 0 11 11 11 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CBY20687.1 - 0.015 15.3 1.7 0.015 15.3 1.7 7.7 10 0 0 10 10 10 0 C2H2-type zinc finger zf-MYST PF17772.1 CBY20687.1 - 0.017 14.7 21.1 0.02 14.5 1.1 6.2 6 0 0 6 6 6 0 MYST family zinc finger domain Actin_micro PF17003.5 CBY20687.1 - 0.91 8.6 30.1 21 4.1 0.6 5.9 1 1 1 3 3 3 0 Putative actin-like family GFO_IDH_MocA PF01408.22 CBY20689.1 - 2.3e-05 25.2 0.0 2.5e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Thioredoxin PF00085.20 CBY20690.1 - 2.7e-74 245.7 1.6 1.2e-19 70.2 0.1 4.4 4 0 0 4 4 4 4 Thioredoxin DnaJ PF00226.31 CBY20690.1 - 3.6e-21 75.1 5.0 5.7e-21 74.4 3.8 2.0 2 0 0 2 2 2 1 DnaJ domain OST3_OST6 PF04756.13 CBY20690.1 - 7.9e-15 55.0 1.3 1.7e-06 27.6 0.1 3.9 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBY20690.1 - 2e-14 53.7 4.2 0.00046 20.5 0.0 6.6 4 4 2 6 6 6 3 Thioredoxin-like Thioredoxin_2 PF13098.6 CBY20690.1 - 7.3e-13 48.9 6.7 0.0039 17.6 0.0 5.7 4 2 0 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY20690.1 - 1.1e-09 38.3 4.7 0.045 13.7 0.0 4.9 5 0 0 5 5 5 3 AhpC/TSA family Thioredoxin_3 PF13192.6 CBY20690.1 - 6e-09 35.8 1.2 0.087 12.9 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin domain Thioredoxin_7 PF13899.6 CBY20690.1 - 1.7e-08 34.5 2.8 0.0061 16.7 0.1 4.5 4 0 0 4 4 4 2 Thioredoxin-like Redoxin PF08534.10 CBY20690.1 - 5.4e-05 22.9 0.3 0.073 12.8 0.0 3.4 3 0 0 3 3 3 1 Redoxin Thioredoxin_6 PF13848.6 CBY20690.1 - 9.1e-05 22.4 0.0 0.82 9.6 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain TraF PF13728.6 CBY20690.1 - 0.0023 17.8 0.3 4 7.2 0.0 3.4 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CBY20690.1 - 0.0091 15.8 0.3 0.71 9.6 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin Tmp39 PF10271.9 CBY20691.1 - 7.8e-37 127.3 11.5 1e-36 126.9 11.5 1.1 1 0 0 1 1 1 1 Putative transmembrane protein CUB PF00431.20 CBY20694.1 - 0.0001 22.6 0.2 0.00022 21.6 0.2 1.5 1 0 0 1 1 1 1 CUB domain zf-RING_5 PF14634.6 CBY20695.1 - 2.7e-07 30.4 17.5 6.4e-07 29.2 17.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY20695.1 - 3.3e-07 30.5 14.7 7.6e-07 29.4 14.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY20695.1 - 6.1e-07 29.2 13.4 1.5e-06 28.0 13.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY20695.1 - 6.2e-06 25.9 11.8 1.8e-05 24.4 11.8 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 CBY20695.1 - 6.3e-06 26.0 17.3 1.8e-05 24.5 17.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY20695.1 - 2.7e-05 23.9 16.2 5.3e-05 23.0 16.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY20695.1 - 0.0032 17.5 9.8 0.015 15.3 10.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY20695.1 - 0.018 15.3 10.2 0.059 13.7 10.2 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CBY20695.1 - 0.021 15.0 12.9 0.081 13.1 13.0 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBY20695.1 - 0.048 13.5 12.8 0.11 12.4 12.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Mu-like_Pro PF10123.9 CBY20695.1 - 0.22 11.1 3.8 0.29 10.7 3.8 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Peptidase_C74 PF12387.8 CBY20695.1 - 0.22 11.0 2.8 0.28 10.6 1.9 1.6 2 0 0 2 2 2 0 Pestivirus NS2 peptidase NAD_binding_5 PF07994.12 CBY20695.1 - 0.32 10.3 3.1 0.48 9.7 3.1 1.4 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase zf-RING_10 PF16685.5 CBY20695.1 - 0.49 10.6 11.6 3 8.0 10.2 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 FemAB_like PF04339.12 CBY20695.1 - 1.2 8.2 5.6 0.7 9.0 3.6 1.5 1 1 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition FYVE PF01363.21 CBY20695.1 - 2.9 8.1 16.1 32 4.7 15.8 2.6 1 1 1 2 2 2 0 FYVE zinc finger TMPIT PF07851.13 CBY20695.1 - 7.9 5.6 9.7 14 4.8 9.7 1.5 1 0 0 1 1 1 0 TMPIT-like protein Acetyltransf_1 PF00583.25 CBY20696.1 - 1.4e-14 54.4 0.0 2.1e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY20696.1 - 3.5e-10 40.1 0.0 7.1e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY20696.1 - 5.3e-07 29.6 0.0 2.5e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY20696.1 - 6.5e-07 29.6 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY20696.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 CBY20696.1 - 0.00077 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 CBY20696.1 - 0.042 13.3 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_9 PF13527.7 CBY20696.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 CBY20697.1 - 0.0003 19.8 22.3 0.0036 16.3 22.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CD34_antigen PF06365.12 CBY20699.1 - 0.0088 15.6 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family GAPT PF11770.8 CBY20699.1 - 0.033 14.1 0.4 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) FAM163 PF15069.6 CBY20699.1 - 0.076 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 FAM163 family Comm PF15957.5 CBY20699.1 - 0.095 13.0 0.1 0.65 10.3 0.1 2.1 2 0 0 2 2 2 0 Commissureless DUF1254 PF06863.12 CBY20700.1 - 1.2e-15 57.8 0.0 4.3e-14 52.7 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 CBY20700.1 - 2.7e-12 47.1 0.0 3.3e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1214) HlyIII PF03006.20 CBY20702.1 - 6.4e-62 209.2 19.8 7.7e-62 208.9 19.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.18 CBY20702.1 - 0.00061 19.7 0.4 0.0009 19.2 0.4 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 CBY20702.1 - 0.12 12.9 6.0 0.44 11.1 6.0 1.9 1 1 0 1 1 1 0 YtxH-like protein HLH PF00010.26 CBY20703.1 - 6.2e-12 45.3 0.1 1e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pepsin-I3 PF06394.13 CBY20704.1 - 0.031 14.4 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain MULE PF10551.9 CBY20705.1 - 6.6e-07 29.7 0.2 6.1e-06 26.6 0.0 2.6 2 1 1 3 3 3 1 MULE transposase domain RT_RNaseH_2 PF17919.1 CBY20707.1 - 1.5e-27 95.5 0.0 3e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY20707.1 - 1.3e-22 80.1 0.0 2.6e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY20707.1 - 9.5e-19 67.7 0.0 2.5e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY20707.1 - 1.6e-07 31.3 0.2 3.6e-07 30.2 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CBY20707.1 - 2.8e-05 23.8 0.1 6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 CBY20707.1 - 0.026 14.4 0.3 0.6 10.0 0.0 3.1 2 1 0 2 2 2 0 Reverse transcriptase thumb domain Ribosomal_L39 PF00832.20 CBY20709.1 - 0.00048 19.7 5.3 0.00059 19.4 3.3 2.1 1 1 1 2 2 2 1 Ribosomal L39 protein Glyco_hydro_63 PF03200.16 CBY20709.1 - 0.021 13.6 0.4 0.022 13.5 0.4 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain APC_u14 PF16635.5 CBY20711.1 - 0.21 12.1 7.4 0.18 12.4 3.2 2.7 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr RGS PF00615.19 CBY20712.1 - 0.0043 17.3 1.1 0.0043 17.3 1.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase PF00069.25 CBY20714.1 - 8.3e-15 54.9 0.4 1.2e-14 54.4 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20714.1 - 3.9e-11 42.7 0.1 5.6e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2859 PF11072.8 CBY20716.1 - 2.3 8.0 4.9 22 4.8 0.1 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF2859) Frizzled PF01534.17 CBY20718.1 - 7.3e-115 383.5 15.2 9.3e-115 383.1 15.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CBY20718.1 - 5.5e-28 97.8 7.5 7e-28 97.5 4.8 2.5 2 0 0 2 2 2 1 Fz domain Jagunal PF07086.12 CBY20718.1 - 0.0086 16.2 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis DUF898 PF05987.13 CBY20718.1 - 0.016 14.3 0.2 0.016 14.3 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) Srg PF02118.21 CBY20718.1 - 0.29 10.7 9.4 0.58 9.8 9.4 1.4 1 0 0 1 1 1 0 Srg family chemoreceptor ASC PF00858.24 CBY20719.1 - 2.5e-104 349.7 1.3 2.9e-104 349.5 1.3 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Kinesin PF00225.23 CBY20720.1 - 3.5e-84 282.6 0.4 5.6e-84 281.9 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY20720.1 - 1.2e-21 77.2 0.0 2.9e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 CBY20720.1 - 0.0003 20.5 0.0 0.0008 19.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CBY20720.1 - 0.0027 18.3 0.0 0.012 16.2 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_3 PF12836.7 CBY20720.1 - 0.0048 17.1 0.0 0.085 13.1 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HNH_4 PF13395.6 CBY20720.1 - 0.042 13.8 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 HNH endonuclease Zwint PF15556.6 CBY20720.1 - 0.073 12.6 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 ZW10 interactor AAA_7 PF12775.7 CBY20720.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PHD PF00628.29 CBY20721.1 - 2e-09 37.2 26.4 7.2e-05 22.6 9.2 2.7 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 CBY20721.1 - 0.0065 16.0 15.6 0.11 12.0 1.9 3.2 2 1 0 2 2 2 2 PHD-finger Zf_RING PF16744.5 CBY20721.1 - 3.6 7.8 18.4 3.7 7.7 3.4 3.1 2 2 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 CBY20721.1 - 4.6 7.4 20.7 36 4.5 3.7 2.9 1 1 1 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 CBY20721.1 - 5.8 7.1 21.3 90 3.3 11.7 2.9 1 1 1 2 2 2 0 PHD-zinc-finger like domain DDT PF02791.17 CBY20722.1 - 1e-07 32.1 3.5 4.6e-07 30.0 1.8 2.3 2 0 0 2 2 2 1 DDT domain WSD PF15613.6 CBY20722.1 - 4.6e-07 30.2 3.2 4.6e-07 30.2 3.2 4.3 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 CBY20722.1 - 0.0001 22.1 8.5 0.00024 20.9 8.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY20722.1 - 0.19 11.3 2.5 0.41 10.2 2.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 CBY20722.1 - 0.22 11.7 5.3 0.66 10.2 5.3 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 CBY20722.1 - 1.5 8.8 4.9 4.6 7.2 4.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 CUE PF02845.16 CBY20723.1 - 1.1e-05 24.9 0.1 2.5e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 CUE domain Importin_rep_6 PF18829.1 CBY20723.1 - 0.37 10.9 0.0 0.37 10.9 0.0 3.2 3 1 0 3 3 3 0 Importin repeat 6 DUF960 PF06124.11 CBY20723.1 - 0.88 10.3 4.6 0.25 12.0 0.7 2.1 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) SIR2 PF02146.17 CBY20725.1 - 1.4e-14 54.4 0.0 2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1258 PF06869.12 CBY20725.1 - 0.09 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) SIR2 PF02146.17 CBY20726.1 - 0.00021 21.3 0.1 0.00034 20.6 0.1 1.4 1 0 0 1 1 1 1 Sir2 family Phi-29_GP16_7 PF06720.11 CBY20726.1 - 0.021 14.6 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 EzrA PF06160.12 CBY20726.1 - 0.062 11.5 0.1 0.075 11.2 0.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TFA2_Winged_2 PF18121.1 CBY20726.1 - 0.072 12.8 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 YvrJ PF12841.7 CBY20726.1 - 0.17 11.4 0.7 0.26 10.9 0.7 1.3 1 0 0 1 1 1 0 YvrJ protein family HEAT PF02985.22 CBY20727.1 - 1.2e-05 25.1 0.4 0.07 13.4 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 CBY20727.1 - 0.0028 18.1 3.6 0.71 10.4 0.1 4.8 4 2 2 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 CBY20727.1 - 0.0076 16.6 0.0 0.65 10.4 0.0 3.0 2 1 1 3 3 3 1 HEAT repeats DUF2681 PF10883.8 CBY20728.1 - 0.036 14.5 0.1 0.058 13.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Chordopox_A13L PF05961.11 CBY20728.1 - 0.73 10.1 2.4 2.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein A_deamin PF02137.18 CBY20730.1 - 7.4e-21 74.9 0.0 1.9e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 Adenosine-deaminase (editase) domain dsrm PF00035.26 CBY20730.1 - 0.00051 20.7 0.3 0.0011 19.6 0.3 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif 2-oxoacid_dh PF00198.23 CBY20731.1 - 9.7e-81 270.6 0.0 1.6e-80 269.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CBY20731.1 - 1.1e-17 63.6 2.4 2.5e-17 62.5 2.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CBY20731.1 - 3.4e-16 59.3 0.2 4.1e-15 55.8 0.2 2.6 2 0 0 2 2 2 1 e3 binding domain HlyD_3 PF13437.6 CBY20731.1 - 0.015 16.0 1.1 8.2 7.2 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 CBY20731.1 - 0.053 13.4 4.1 2.1 8.2 0.4 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like Ion_trans PF00520.31 CBY20733.1 - 1.1e-33 116.5 13.6 1.6e-33 116.0 13.6 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY20733.1 - 1.7e-15 56.7 4.4 1.7e-15 56.7 4.4 2.6 3 0 0 3 3 3 1 Ion channel BTB_2 PF02214.22 CBY20733.1 - 2.4e-12 47.1 0.1 5e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF1029 PF06269.12 CBY20733.1 - 0.018 15.2 0.0 0.018 15.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1029) PKD_channel PF08016.12 CBY20733.1 - 0.19 10.3 5.3 0.042 12.5 1.8 1.6 1 1 1 2 2 2 0 Polycystin cation channel DUF21 PF01595.20 CBY20733.1 - 2.3 7.9 6.5 0.14 11.8 0.8 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Pup PF05639.11 CBY20734.1 - 0.07 14.0 2.1 0.29 12.1 1.0 2.4 2 1 0 2 2 2 0 Pup-like protein TRIC PF05197.13 CBY20735.1 - 8.8e-21 74.4 2.1 1.2e-20 73.9 2.1 1.2 1 0 0 1 1 1 1 TRIC channel FSH1 PF03959.13 CBY20735.1 - 0.056 13.1 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) FtsX PF02687.21 CBY20735.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.3 2 1 0 2 2 2 0 FtsX-like permease family DUF624 PF04854.14 CBY20735.1 - 0.18 11.9 5.7 0.2 11.8 1.5 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF624 TRIC PF05197.13 CBY20737.1 - 9.1e-21 74.3 2.1 1.3e-20 73.8 2.1 1.2 1 0 0 1 1 1 1 TRIC channel FSH1 PF03959.13 CBY20737.1 - 0.057 13.1 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) FtsX PF02687.21 CBY20737.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.3 2 1 0 2 2 2 0 FtsX-like permease family DUF624 PF04854.14 CBY20737.1 - 0.16 12.1 5.5 0.16 12.1 1.5 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF624 Sre PF03125.18 CBY20737.1 - 5 6.2 8.0 0.28 10.3 0.4 2.3 2 1 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor BAR_3_WASP_bdg PF10456.9 CBY20740.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DUF4097 PF13349.6 CBY20742.1 - 9.9e-08 31.6 10.8 1.8e-07 30.8 9.5 2.1 1 1 1 2 2 2 1 Putative adhesin DUF2345 PF10106.9 CBY20742.1 - 0.049 13.5 1.1 4.1 7.3 0.1 2.7 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2345) YIF1 PF03878.15 CBY20743.1 - 0.0022 17.5 5.9 0.15 11.6 5.2 2.2 1 1 0 1 1 1 1 YIF1 Na_Ca_ex PF01699.24 CBY20743.1 - 0.54 10.2 11.0 0.15 12.0 4.7 2.3 1 1 1 2 2 2 0 Sodium/calcium exchanger protein Yip1 PF04893.17 CBY20743.1 - 0.76 9.5 11.1 1.3 8.7 11.1 1.4 1 1 0 1 1 1 0 Yip1 domain WD40 PF00400.32 CBY20744.1 - 7.8e-28 96.2 7.5 1e-06 29.4 0.2 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20744.1 - 1.6e-09 37.9 0.1 0.21 11.9 0.0 4.9 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 PF13923.6 CBY20745.1 - 5.5e-09 35.7 6.0 1e-08 34.9 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY20745.1 - 1.8e-06 27.7 6.2 3.7e-06 26.7 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY20745.1 - 7.4e-06 26.2 5.1 1.3e-05 25.4 5.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBY20745.1 - 3.3e-05 24.1 1.7 0.00027 21.2 3.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY20745.1 - 4.9e-05 23.2 5.8 8.9e-05 22.4 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY20745.1 - 0.00017 21.4 4.6 0.00026 20.8 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY20745.1 - 0.00025 20.8 3.7 0.00048 19.9 3.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY20745.1 - 0.0024 17.7 2.1 0.0047 16.8 2.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 CBY20745.1 - 0.0029 17.5 2.2 0.0049 16.7 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY20745.1 - 0.0051 16.8 4.0 0.014 15.4 4.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-UDP PF14569.6 CBY20745.1 - 0.011 15.8 3.6 0.066 13.3 2.4 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 CBY20745.1 - 0.049 13.8 4.7 0.11 12.7 4.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 CBY20745.1 - 0.11 12.6 2.7 0.22 11.7 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.8 CBY20745.1 - 0.24 11.3 3.4 0.53 10.2 3.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Wzz PF02706.15 CBY20746.1 - 0.4 11.0 2.5 1.6 9.0 0.3 3.1 2 0 0 2 2 2 0 Chain length determinant protein Spc7 PF08317.11 CBY20746.1 - 1.3 7.8 102.9 0.8 8.5 29.0 5.1 2 1 3 5 5 5 0 Spc7 kinetochore protein zf-MIZ PF02891.20 CBY20747.1 - 1.1e-20 73.0 6.9 2.2e-20 72.1 6.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.6 CBY20747.1 - 1.5e-12 48.1 0.7 3.3e-12 47.0 0.0 1.9 2 1 0 2 2 2 1 PINIT domain zf-Nse PF11789.8 CBY20747.1 - 4.1e-06 26.5 4.7 8.1e-06 25.6 4.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 CBY20747.1 - 0.41 10.5 6.7 0.96 9.3 6.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) bVLRF1 PF18826.1 CBY20748.1 - 0.013 15.3 0.1 0.017 15.0 0.1 1.1 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor Peptidase_M35 PF02102.15 CBY20748.1 - 0.077 11.9 2.2 0.06 12.2 0.8 1.5 1 1 0 1 1 1 0 Deuterolysin metalloprotease (M35) family tRNA-synt_1d PF00750.19 CBY20749.1 - 2.7e-134 447.6 2.6 4.5e-134 446.8 2.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CBY20749.1 - 4.9e-25 88.0 0.1 4.9e-25 88.0 0.1 2.4 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CBY20749.1 - 1.4e-19 70.5 0.2 5.4e-19 68.6 0.2 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 CBY20749.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain ANAPC2 PF08672.11 CBY20749.1 - 0.27 11.7 1.0 3 8.4 0.1 2.7 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 FlxA PF14282.6 CBY20749.1 - 2.9 8.0 9.3 22 5.1 6.7 2.4 2 0 0 2 2 2 0 FlxA-like protein Delta_lysin PF05372.11 CBY20750.1 - 0.081 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Delta lysin family Vac14_Fig4_bd PF11916.8 CBY20751.1 - 0.061 13.0 0.1 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding RnlB_antitoxin PF15933.5 CBY20751.1 - 0.064 13.6 0.0 0.33 11.3 0.0 2.0 1 1 1 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA Peptidase_S41_N PF11918.8 CBY20751.1 - 0.11 12.7 0.7 4.3 7.6 0.1 2.2 1 1 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Choline_kin_N PF04428.14 CBY20751.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Choline kinase N terminus Actin PF00022.19 CBY20752.1 - 2e-37 128.8 0.0 2.1e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.19 CBY20753.1 - 3.9e-27 94.9 0.0 4.6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 CBY20753.1 - 0.087 11.4 0.0 0.099 11.2 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Actin PF00022.19 CBY20754.1 - 4.3e-58 196.9 0.0 4.6e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Actin Med27 PF11571.8 CBY20755.1 - 2.5e-27 95.0 1.0 2.9e-27 94.8 1.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 27 Med27 PF11571.8 CBY20756.1 - 3.1e-21 75.5 1.0 2.4e-20 72.7 0.4 2.4 2 0 0 2 2 2 1 Mediator complex subunit 27 Ank_2 PF12796.7 CBY20758.1 - 3.7e-28 97.9 2.6 5e-10 39.8 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY20758.1 - 4.3e-28 97.3 3.8 2.7e-06 27.8 0.1 6.5 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY20758.1 - 4.8e-27 93.7 10.7 1.7e-08 34.6 0.0 6.4 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 CBY20758.1 - 4.1e-22 77.6 13.0 3.6e-05 24.0 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 CBY20758.1 - 5.8e-17 60.1 6.7 0.00053 20.2 0.0 7.5 8 0 0 8 8 8 3 Ankyrin repeat DUF5344 PF17279.2 CBY20758.1 - 0.041 14.4 1.7 0.84 10.3 0.1 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5344) GAIN_A PF18619.1 CBY20758.1 - 0.087 13.0 0.1 0.33 11.2 0.1 2.1 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF2730 PF10805.8 CBY20758.1 - 0.11 12.6 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) dNK PF01712.19 CBY20759.1 - 1.9e-19 70.4 3.1 1e-18 68.0 3.1 1.9 1 1 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 CBY20759.1 - 7.5e-06 25.7 0.5 3e-05 23.8 0.1 2.0 2 1 0 2 2 2 1 Thymidylate kinase AAA_17 PF13207.6 CBY20759.1 - 0.12 12.8 0.0 3.3 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CBY20760.1 - 7.1e-46 156.2 0.0 1.1e-44 152.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY20760.1 - 3e-23 82.3 0.2 8.9e-23 80.8 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY20760.1 - 4.9e-06 26.7 0.0 0.00015 21.8 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit KH_1 PF00013.29 CBY20760.1 - 0.00013 21.7 0.8 0.00027 20.7 0.8 1.6 1 0 0 1 1 1 1 KH domain Init_tRNA_PT PF04179.12 CBY20760.1 - 0.013 15.8 0.1 0.27 11.5 0.0 2.7 2 0 0 2 2 2 0 Rit1 DUSP-like domain Herpes_UL55 PF04537.12 CBY20760.1 - 0.017 15.1 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein CMS1 PF14617.6 CBY20760.1 - 0.021 14.2 0.0 0.085 12.2 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Glyco_tran_WecB PF03808.13 CBY20760.1 - 0.034 14.1 0.0 0.21 11.5 0.0 2.2 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family EF-hand_7 PF13499.6 CBY20761.1 - 1.1e-17 64.2 16.6 2.3e-10 40.8 0.4 2.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBY20761.1 - 9.3e-17 59.3 12.8 6.2e-07 28.5 1.6 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY20761.1 - 3.8e-16 58.7 8.8 3.1e-12 46.2 0.7 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CBY20761.1 - 2e-15 55.3 8.4 1.2e-06 28.0 0.6 4.4 3 1 2 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 CBY20761.1 - 8.6e-09 34.5 9.6 4.5e-05 22.7 0.4 3.7 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 CBY20761.1 - 0.0048 16.8 3.3 0.087 12.8 0.3 2.4 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SurA_N_2 PF13623.6 CBY20761.1 - 0.019 14.8 0.5 0.067 13.1 0.1 2.0 1 1 1 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 CBY20761.1 - 0.033 14.5 0.4 9.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1456 PF07308.13 CBY20761.1 - 0.034 14.5 0.3 7.4 7.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) UBA PF00627.31 CBY20762.1 - 2.3e-29 100.9 0.3 1.5e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 CBY20762.1 - 9.2e-20 70.1 13.8 2e-19 69.0 13.8 1.6 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 CBY20762.1 - 3.5e-16 58.7 0.7 1e-15 57.3 0.7 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY20762.1 - 0.0002 21.1 1.0 0.00044 20.0 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CBY20762.1 - 0.00092 19.3 0.1 0.0022 18.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF1296 PF06972.11 CBY20762.1 - 0.02 15.0 0.0 1.7 8.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) CUE PF02845.16 CBY20762.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 CUE domain Ubiquitin_4 PF18036.1 CBY20762.1 - 0.17 11.9 1.4 6.6 6.9 1.0 2.6 2 1 0 2 2 2 0 Ubiquitin-like domain STI1 PF17830.1 CBY20762.1 - 0.54 10.2 5.0 0.46 10.5 0.7 2.9 2 1 0 2 2 2 0 STI1 domain TFIIA PF03153.13 CBY20762.1 - 2.2 8.2 13.8 3.1 7.7 13.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Creb_binding PF09030.10 CBY20762.1 - 4.6 8.0 11.0 1.4 9.6 7.3 2.2 1 1 1 2 2 2 0 Creb binding zf-ZPR1 PF03367.13 CBY20763.1 - 7e-84 279.5 8.4 2.5e-46 157.4 1.9 3.1 3 0 0 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.19 CBY20763.1 - 0.0023 17.9 5.9 0.36 10.9 0.3 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 CBY20763.1 - 0.044 13.9 5.1 0.046 13.8 0.1 2.4 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type UPF0547 PF10571.9 CBY20763.1 - 1.1 9.5 3.5 9.7 6.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 SF3A2 PF16835.5 CBY20764.1 - 8.3e-38 128.7 0.1 1.3e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CBY20764.1 - 4e-07 30.2 2.0 4e-07 30.2 2.0 2.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 CBY20764.1 - 0.0021 18.0 0.3 0.0033 17.4 0.3 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein ARGLU PF15346.6 CBY20766.1 - 1.8e-40 138.3 21.5 1.8e-40 138.3 21.5 2.1 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 Arena_nucleocap PF00843.17 CBY20766.1 - 0.00065 18.7 2.5 0.00091 18.2 2.4 1.5 1 1 0 1 1 1 1 Arenavirus nucleocapsid N-terminal domain CCDC-167 PF15188.6 CBY20766.1 - 0.0029 17.9 6.0 0.0029 17.9 6.0 3.4 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 167 ETF_QO PF05187.13 CBY20767.1 - 1.1e-43 147.5 0.0 2.1e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CBY20767.1 - 1.4e-07 31.4 0.5 0.001 18.8 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBY20767.1 - 3.1e-06 27.3 0.1 2.8e-05 24.2 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBY20767.1 - 3.2e-06 26.6 0.0 9.6e-06 25.0 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBY20767.1 - 6.8e-05 22.2 0.0 0.00035 19.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 CBY20767.1 - 0.00012 21.3 1.6 0.0085 15.2 1.5 2.2 1 1 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.7 CBY20767.1 - 0.00023 21.7 3.3 0.00052 20.6 3.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 CBY20767.1 - 0.00031 21.2 0.1 1.7 9.2 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY20767.1 - 0.00035 19.9 0.1 0.00054 19.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CBY20767.1 - 0.001 17.8 0.2 0.0016 17.2 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 CBY20767.1 - 0.0016 18.4 0.1 0.0034 17.4 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_17 PF13534.6 CBY20767.1 - 0.0036 17.8 0.6 0.0083 16.6 0.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBY20767.1 - 0.0037 17.4 2.3 0.0099 16.0 2.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 CBY20767.1 - 0.0082 15.4 0.2 0.013 14.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBY20767.1 - 0.016 14.3 0.2 0.03 13.4 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_21 PF14697.6 CBY20767.1 - 0.044 13.9 1.8 0.088 13.0 1.8 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 CBY20767.1 - 0.048 12.5 0.1 0.6 8.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_2 PF12797.7 CBY20767.1 - 0.055 13.6 2.1 0.14 12.3 2.1 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain FAD_oxidored PF12831.7 CBY20767.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 CBY20767.1 - 0.18 10.9 0.2 0.25 10.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 CBY20767.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_10 PF13237.6 CBY20767.1 - 0.23 11.6 7.1 0.32 11.1 5.7 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 CBY20767.1 - 0.42 10.5 5.1 0.17 11.7 2.3 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 CBY20767.1 - 1.7 8.8 5.3 1.2 9.3 2.9 2.1 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_4 PF12800.7 CBY20767.1 - 6.1 7.6 7.9 3 8.6 4.8 2.1 2 0 0 2 2 1 0 4Fe-4S binding domain DUF4203 PF13886.6 CBY20768.1 - 4.3e-37 127.8 27.9 5.6e-37 127.4 27.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF1656 PF07869.12 CBY20768.1 - 0.011 15.7 0.7 0.011 15.7 0.7 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1656) HCMV_UL124 PF17609.2 CBY20768.1 - 0.086 13.0 0.2 0.086 13.0 0.2 2.4 3 0 0 3 3 3 0 Family of unknown function DUF5336 PF17270.2 CBY20768.1 - 3.3 7.3 6.0 16 5.1 3.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5336) YusW PF14039.6 CBY20769.1 - 0.0084 16.6 0.0 3.2 8.3 0.0 2.2 2 0 0 2 2 2 2 YusW-like protein Aminotran_3 PF00202.21 CBY20769.1 - 0.022 13.4 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III RGS12_us2 PF16611.5 CBY20769.1 - 0.041 14.3 0.6 0.07 13.5 0.6 1.3 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco TYA PF01021.19 CBY20769.1 - 0.11 12.9 0.4 0.18 12.2 0.4 1.3 1 0 0 1 1 1 0 TYA transposon protein SID-1_RNA_chan PF13965.6 CBY20771.1 - 0.015 13.8 0.1 0.018 13.5 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UCR_UQCRX_QCR9 PF05365.12 CBY20771.1 - 0.093 12.7 0.7 4.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Kei1 PF08552.11 CBY20771.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FGFR3_TM PF18123.1 CBY20771.1 - 3 7.4 7.7 5.2 6.7 7.7 1.2 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain Trypsin PF00089.26 CBY20772.1 - 6.4e-65 219.0 0.1 1.6e-64 217.8 0.1 1.7 1 1 0 1 1 1 1 Trypsin CUB PF00431.20 CBY20772.1 - 6.5e-34 116.6 3.2 6.5e-17 61.9 0.2 2.7 3 0 0 3 3 3 2 CUB domain DUF1986 PF09342.11 CBY20772.1 - 0.002 18.5 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Tmem26 PF09772.9 CBY20773.1 - 1.2e-42 146.3 5.7 3.8e-42 144.6 5.7 1.7 1 1 0 1 1 1 1 Transmembrane protein 26 CECR6_TMEM121 PF14997.6 CBY20773.1 - 0.0051 16.7 2.4 0.0051 16.7 2.4 3.2 2 1 1 3 3 3 1 CECR6/TMEM121 family Astacin PF01400.24 CBY20774.1 - 2e-12 47.2 0.0 6.3e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY20774.1 - 3.5e-07 30.3 4.2 3.5e-07 30.3 4.2 4.1 4 0 0 4 4 4 1 Calcium-binding EGF domain Gly_transf_sug PF04488.15 CBY20775.1 - 6.6e-10 39.5 0.2 1e-08 35.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 CBY20775.1 - 0.058 12.7 2.4 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain WBP-1 PF11669.8 CBY20777.1 - 0.031 14.9 1.9 0.047 14.3 0.0 2.1 2 1 0 2 2 2 0 WW domain-binding protein 1 Galactosyl_T PF01762.21 CBY20778.1 - 5.6e-19 68.7 0.0 1.4e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase RRM_1 PF00076.22 CBY20779.1 - 7.1e-22 77.0 0.0 9.9e-10 38.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-LYAR PF08790.11 CBY20779.1 - 2.8e-12 46.3 2.3 2.8e-12 46.3 2.3 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger NPM1-C PF16276.5 CBY20779.1 - 0.0024 17.8 0.0 0.011 15.6 0.0 2.2 1 0 0 1 1 1 1 Nucleophosmin C-terminal domain ComA PF02679.15 CBY20779.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) zf-TRAF PF02176.18 CBY20779.1 - 0.024 15.3 2.7 0.054 14.2 2.7 1.7 1 0 0 1 1 1 0 TRAF-type zinc finger BRAP2 PF07576.12 CBY20779.1 - 0.03 14.6 0.0 3 8.1 0.0 2.4 2 0 0 2 2 2 0 BRCA1-associated protein 2 RIC1 PF07064.13 CBY20780.1 - 8.9e-85 284.1 0.1 1.7e-84 283.2 0.1 1.5 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CBY20780.1 - 0.089 13.1 0.0 1.6 9.1 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DED PF01335.21 CBY20780.1 - 0.67 10.3 5.3 0.16 12.3 1.3 2.1 2 0 0 2 2 2 0 Death effector domain Glyco_hydro_20 PF00728.22 CBY20781.1 - 2e-06 27.5 0.0 5.3e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain FlaC_arch PF05377.11 CBY20781.1 - 0.016 15.5 0.6 1.1 9.7 1.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) EF-G-binding_N PF07299.11 CBY20781.1 - 1 9.9 7.6 4 8.0 3.5 3.5 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal DUF2859 PF11072.8 CBY20782.1 - 1.1 8.9 5.9 11 5.8 0.1 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF2859) MFS_1 PF07690.16 CBY20784.1 - 5.3e-26 91.4 14.5 5.3e-26 91.4 14.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY20784.1 - 0.00063 18.7 16.3 0.026 13.4 3.1 2.5 2 1 0 2 2 2 2 MFS_1 like family GWT1 PF06423.12 CBY20784.1 - 0.57 10.3 6.1 57 3.8 0.0 3.6 2 1 0 2 2 2 0 GWT1 DUF423 PF04241.15 CBY20784.1 - 9.3 6.5 9.3 0.71 10.1 1.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF423) RhoGEF PF00621.20 CBY20785.1 - 1.4e-29 103.7 0.3 3.3e-29 102.4 0.3 1.7 1 0 0 1 1 1 1 RhoGEF domain BRCT PF00533.26 CBY20785.1 - 1.9e-09 37.8 0.0 0.0044 17.4 0.0 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CBY20785.1 - 0.0022 18.2 0.0 0.0063 16.8 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 CBY20785.1 - 0.0037 17.2 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain MMR_HSR1_Xtn PF16897.5 CBY20786.1 - 1.5e-41 140.7 0.9 2.6e-41 139.9 0.9 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CBY20786.1 - 2.3e-19 69.2 0.1 4.3e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CBY20786.1 - 8.2e-19 67.8 0.0 2.3e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY20786.1 - 3.8e-10 39.5 0.2 2.1e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CBY20786.1 - 0.0017 17.4 0.3 0.023 13.7 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 CBY20786.1 - 0.0025 17.4 0.0 1.5 8.3 0.0 3.6 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBY20786.1 - 0.041 13.9 0.4 3.5 7.6 0.2 2.5 1 1 1 2 2 2 0 Dynamin family RhoGEF PF00621.20 CBY20788.1 - 1e-27 97.6 0.0 1.4e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 CBY20789.1 - 2.1e-12 46.7 0.1 8.5e-11 41.5 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY20789.1 - 2.3e-09 36.7 0.3 1.2e-08 34.4 0.0 2.3 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.17 CBY20789.1 - 2.4e-08 33.5 0.0 2.2e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.6 CBY20789.1 - 6e-05 23.4 0.0 0.019 15.4 0.0 2.4 2 0 0 2 2 2 2 Helically-extended SH3 domain DUF559 PF04480.12 CBY20789.1 - 0.0058 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) SH3_3 PF08239.11 CBY20789.1 - 0.018 15.3 0.6 0.062 13.6 0.2 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain BAR PF03114.18 CBY20789.1 - 0.14 11.8 2.2 0.64 9.6 0.6 2.2 1 1 1 2 2 2 0 BAR domain MapZ_EC1 PF18041.1 CBY20792.1 - 0.022 15.0 0.2 0.047 13.9 0.2 1.6 1 1 0 1 1 1 0 MapZ extracellular domain 1 DUF4434 PF14488.6 CBY20792.1 - 0.087 12.8 0.5 0.18 11.8 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Kri1 PF05178.12 CBY20792.1 - 1.4 9.5 8.9 0.16 12.5 2.2 2.3 1 1 1 2 2 2 0 KRI1-like family zf-C2H2 PF00096.26 CBY20793.1 - 9.4e-14 51.0 22.3 5.4e-05 23.4 0.9 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CBY20793.1 - 1.7e-11 43.8 8.4 0.00012 22.0 1.2 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY20793.1 - 1.2e-10 41.3 20.0 6.5e-07 29.5 0.0 4.0 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY20793.1 - 2.6e-08 33.9 10.0 0.024 14.9 1.4 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CBY20793.1 - 1.5e-07 31.7 23.6 0.015 16.1 1.1 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 CBY20793.1 - 1.5e-05 25.2 12.6 0.045 14.2 0.0 4.0 4 0 0 4 4 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CBY20793.1 - 0.00015 21.9 0.5 0.00015 21.9 0.5 3.0 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Arm PF00514.23 CBY20793.1 - 0.03 14.4 1.0 45 4.3 0.0 4.9 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat LRR_9 PF14580.6 CBY20793.1 - 0.031 13.8 0.1 0.1 12.1 0.1 1.8 1 0 0 1 1 1 0 Leucine-rich repeat DUF3541 PF12060.8 CBY20793.1 - 0.045 13.4 0.2 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) Ric8 PF10165.9 CBY20793.1 - 1.9 7.4 9.1 0.27 10.2 1.0 2.8 1 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn VWA PF00092.28 CBY20794.1 - 0.0018 18.6 0.6 0.0033 17.7 0.6 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain COBRA PF04833.15 CBY20794.1 - 0.039 13.9 0.6 0.09 12.7 0.6 1.6 1 0 0 1 1 1 0 COBRA-like protein VEG PF06257.11 CBY20794.1 - 0.043 13.9 0.0 1.8 8.7 0.0 3.0 3 0 0 3 3 3 0 Biofilm formation stimulator VEG OSTbeta PF15048.6 CBY20794.1 - 0.48 10.6 8.3 0.13 12.4 0.5 2.8 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein Nop25 PF09805.9 CBY20794.1 - 3.2 8.2 11.3 0.53 10.8 5.5 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PcfK PF14058.6 CBY20794.1 - 3.6 7.9 8.0 0.77 10.0 2.2 2.4 2 0 0 2 2 2 0 PcfK-like protein Raftlin PF15250.6 CBY20794.1 - 9.9 4.8 10.7 0.17 10.6 1.0 2.2 2 1 0 2 2 2 0 Raftlin Ion_trans PF00520.31 CBY20795.1 - 8.9e-29 100.4 16.6 1.2e-28 100.0 16.6 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY20795.1 - 2.9e-11 43.3 0.0 5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CBY20795.1 - 9.8e-10 38.3 7.9 9.8e-10 38.3 7.9 2.6 2 1 0 2 2 2 1 Ion channel HSBP1 PF06825.12 CBY20795.1 - 0.21 11.4 1.2 0.99 9.3 1.8 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Cornichon PF03311.14 CBY20795.1 - 0.32 11.3 7.2 0.67 10.3 2.3 2.5 2 0 0 2 2 2 0 Cornichon protein Collagen PF01391.18 CBY20796.1 - 2.4e-19 68.8 73.0 1.8e-08 34.0 29.9 3.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY20796.1 - 7.2e-08 32.9 0.6 9.8e-08 32.4 0.6 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY20796.1 - 0.053 14.2 0.1 0.084 13.5 0.1 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Filamin PF00630.19 CBY20797.1 - 0 1051.2 54.8 6.8e-19 68.6 0.0 22.2 22 0 0 22 22 22 22 Filamin/ABP280 repeat CH PF00307.31 CBY20797.1 - 9.1e-37 125.6 0.1 8.2e-21 74.2 0.4 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF5060 PF16586.5 CBY20797.1 - 2.2e-15 56.7 0.0 16 6.0 0.0 13.8 16 0 0 16 16 16 0 Domain of unknown function (DUF5060) Y_Y_Y PF07495.13 CBY20797.1 - 2.4e-15 56.3 2.8 1.2 9.2 0.0 11.1 13 0 0 13 13 13 4 Y_Y_Y domain Invasin_D3 PF09134.10 CBY20797.1 - 2.5e-08 34.1 11.3 17 5.8 0.0 11.4 11 2 1 12 12 12 0 Invasin, domain 3 Big_3_5 PF16640.5 CBY20797.1 - 1.8e-06 28.0 40.4 0.59 10.4 0.4 13.0 15 0 0 15 15 15 4 Bacterial Ig-like domain (group 3) Big_6 PF17936.1 CBY20797.1 - 1.5e-05 25.2 14.9 1.8 8.9 0.2 9.8 10 0 0 10 10 9 1 Bacterial Ig domain Cadherin_5 PF17892.1 CBY20797.1 - 0.0015 18.4 1.7 4.3 7.4 0.1 6.1 7 0 0 7 7 7 1 Cadherin-like domain CarboxypepD_reg PF13620.6 CBY20797.1 - 0.0029 17.8 17.8 1.9 8.8 0.1 9.1 12 1 1 13 13 13 2 Carboxypeptidase regulatory-like domain CAMSAP_CH PF11971.8 CBY20797.1 - 0.0065 16.3 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain EMP24_GP25L PF01105.24 CBY20797.1 - 0.013 15.5 12.6 10 6.0 0.0 7.5 10 0 0 10 10 10 0 emp24/gp25L/p24 family/GOLD Big_3 PF07523.12 CBY20797.1 - 0.035 14.4 20.5 4.8 7.5 0.0 11.5 15 2 2 17 17 13 0 Bacterial Ig-like domain (group 3) Rib PF08428.10 CBY20797.1 - 0.073 13.1 3.6 7.4 6.6 0.0 4.2 3 0 0 3 3 3 0 Rib/alpha-like repeat zf-Sec23_Sec24 PF04810.15 CBY20798.1 - 0.0026 17.8 2.2 0.41 10.8 0.1 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 CBY20798.1 - 0.14 12.5 2.2 18 5.7 0.2 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBY20798.1 - 2.1 9.4 5.5 23 6.2 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 CBY20798.1 - 9.5 6.3 7.0 5 7.2 3.2 2.3 2 0 0 2 2 2 0 BED zinc finger TFIIIC_delta PF12657.7 CBY20799.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term DUF4315 PF14193.6 CBY20800.1 - 0.023 14.7 1.6 0.023 14.7 1.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) PA28_beta PF02252.18 CBY20802.1 - 1.4e-59 199.9 0.4 2.2e-59 199.3 0.4 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 CBY20802.1 - 2e-09 37.4 0.0 4.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit SF3a60_bindingd PF12108.8 CBY20802.1 - 0.014 15.3 0.3 0.49 10.3 0.1 2.6 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain YscO PF07321.12 CBY20802.1 - 0.037 14.0 0.5 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Type III secretion protein YscO BshC PF10079.9 CBY20802.1 - 0.066 11.9 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC TetR_C_4 PF08359.11 CBY20802.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region TMF_TATA_bd PF12325.8 CBY20802.1 - 0.14 12.4 0.7 1.2 9.3 0.0 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NTP_transferase PF00483.23 CBY20803.1 - 1.2e-48 165.9 0.0 1.7e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CBY20803.1 - 3.5e-10 39.2 4.6 1.1e-08 34.5 2.5 3.0 2 2 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CBY20803.1 - 2e-09 38.0 0.0 2.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CBY20803.1 - 6.4e-05 22.6 2.1 0.0003 20.5 2.1 2.2 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 CBY20803.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase WD40 PF00400.32 CBY20804.1 - 1.3e-22 79.6 1.2 1.3e-05 25.9 0.0 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20804.1 - 3.1e-07 30.6 0.0 0.00027 21.2 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY20804.1 - 3.3e-05 22.8 1.1 0.01 14.6 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CBY20804.1 - 0.00021 21.2 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY20804.1 - 0.094 12.0 0.0 1 8.7 0.0 1.9 1 1 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 CBY20804.1 - 0.14 11.1 2.5 0.17 10.8 0.1 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PA28_beta PF02252.18 CBY20805.1 - 1.4e-59 199.9 0.4 2.2e-59 199.3 0.4 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 CBY20805.1 - 2e-09 37.4 0.0 4.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit SF3a60_bindingd PF12108.8 CBY20805.1 - 0.014 15.3 0.3 0.49 10.3 0.1 2.6 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain YscO PF07321.12 CBY20805.1 - 0.037 14.0 0.5 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Type III secretion protein YscO BshC PF10079.9 CBY20805.1 - 0.066 11.9 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC TetR_C_4 PF08359.11 CBY20805.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region TMF_TATA_bd PF12325.8 CBY20805.1 - 0.14 12.4 0.7 1.2 9.3 0.0 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NTP_transferase PF00483.23 CBY20806.1 - 1.2e-48 165.9 0.0 1.7e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CBY20806.1 - 3.5e-10 39.2 4.6 1.1e-08 34.5 2.5 3.0 2 2 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CBY20806.1 - 2e-09 38.0 0.0 2.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CBY20806.1 - 6.4e-05 22.6 2.1 0.0003 20.5 2.1 2.2 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 CBY20806.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase WD40 PF00400.32 CBY20807.1 - 3e-61 201.9 18.3 9.1e-12 45.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20807.1 - 3.5e-24 84.9 1.7 0.00016 21.9 0.1 5.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY20807.1 - 1.8e-12 46.7 8.2 0.0014 17.4 0.5 5.8 1 1 5 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 CBY20807.1 - 3e-10 40.3 0.2 0.00014 21.8 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBY20807.1 - 1.3e-09 37.5 4.5 0.02 13.8 0.0 4.2 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBY20807.1 - 9.9e-06 25.1 0.0 0.14 11.5 0.0 3.5 1 1 3 4 4 4 3 WD40-like domain BBS2_Mid PF14783.6 CBY20807.1 - 0.016 15.2 0.0 2.3 8.3 0.0 3.4 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 CBY20807.1 - 0.035 12.4 0.1 7 4.8 0.0 2.5 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 CBY20807.1 - 0.11 11.5 0.9 8.8 5.3 0.0 3.1 3 1 1 4 4 4 0 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 CBY20807.1 - 1.2 7.8 4.2 14 4.3 0.1 3.4 1 1 3 4 4 4 0 Nup133 N terminal like Hist_deacetyl PF00850.19 CBY20808.1 - 4.3e-85 285.9 0.0 5.2e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Rhodanese PF00581.20 CBY20809.1 - 2.7e-09 37.5 0.0 5.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain MFS_5 PF05631.14 CBY20810.1 - 2.9e-50 171.2 9.4 4.1e-50 170.7 9.4 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CBY20810.1 - 4e-10 39.1 24.6 8.5e-05 21.6 3.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF908 PF06012.12 CBY20812.1 - 0.16 11.4 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) WD40 PF00400.32 CBY20813.1 - 0.012 16.4 1.5 4.2 8.4 0.9 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Lge1 PF11488.8 CBY20814.1 - 0.048 13.9 0.2 0.2 11.9 0.0 2.1 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Arteri_nucleo PF01481.16 CBY20814.1 - 0.092 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein zf-C3HC4 PF00097.25 CBY20815.1 - 8.2e-09 35.2 7.3 1.3e-08 34.6 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY20815.1 - 1.3e-08 34.6 7.6 2.3e-08 33.7 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY20815.1 - 8.6e-08 32.1 3.6 2e-07 30.9 3.5 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CBY20815.1 - 1.2e-07 31.8 8.6 1.8e-07 31.2 8.6 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBY20815.1 - 3.3e-06 27.3 10.3 5.2e-06 26.7 10.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CBY20815.1 - 1e-05 25.5 2.9 1.5e-05 25.0 2.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CBY20815.1 - 1.7e-05 24.6 8.3 2.8e-05 23.9 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY20815.1 - 1.8e-05 24.6 7.7 4e-05 23.5 7.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 CBY20815.1 - 0.00053 19.8 3.4 0.00098 18.9 3.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CBY20815.1 - 0.00089 19.0 10.4 0.0021 17.8 10.4 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY20815.1 - 0.0017 18.2 9.7 0.0076 16.1 7.6 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CBY20815.1 - 0.0048 17.0 7.9 0.0067 16.5 7.9 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zinc_ribbon_9 PF14369.6 CBY20815.1 - 0.006 16.8 4.0 0.006 16.8 4.0 2.4 2 0 0 2 2 2 1 zinc-ribbon zinc_ribbon_4 PF13717.6 CBY20815.1 - 0.0092 15.9 0.8 0.0092 15.9 0.8 2.8 3 0 0 3 3 3 1 zinc-ribbon domain zf-rbx1 PF12678.7 CBY20815.1 - 0.014 15.6 11.7 0.11 12.8 12.0 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 CBY20815.1 - 0.042 13.6 8.7 0.07 12.9 8.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-UDP PF14569.6 CBY20815.1 - 0.11 12.7 8.4 0.28 11.3 8.4 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.21 CBY20815.1 - 0.13 12.5 6.7 0.3 11.2 0.0 2.8 1 1 1 2 2 2 0 FYVE zinc finger zinc_ribbon_5 PF13719.6 CBY20815.1 - 0.23 11.2 3.4 0.37 10.6 0.3 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zf-Nse PF11789.8 CBY20815.1 - 0.24 11.3 4.1 0.36 10.7 4.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 CBY20815.1 - 0.39 10.8 9.3 6.7 6.8 0.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon DpnI PF06044.12 CBY20815.1 - 0.5 10.0 5.5 1.3 8.6 5.5 1.7 1 1 0 1 1 1 0 Dam-replacing family IBR PF01485.21 CBY20815.1 - 2.5 8.4 9.6 1.6 9.0 4.2 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain HCV_env PF01539.17 CBY20816.1 - 0.019 14.7 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 Vg_Tdu PF07545.14 CBY20816.1 - 0.047 13.5 1.4 6.3 6.7 0.2 2.4 2 0 0 2 2 2 0 Vestigial/Tondu family UNC-50 PF05216.13 CBY20817.1 - 3.7e-77 258.8 20.9 4.3e-77 258.6 20.9 1.0 1 0 0 1 1 1 1 UNC-50 family Porin_6 PF16939.5 CBY20817.1 - 0.037 13.1 2.7 2.2 7.3 0.3 2.1 2 0 0 2 2 2 0 Putative porin PRRSV_2b PF07069.11 CBY20817.1 - 0.57 10.7 0.2 0.57 10.7 0.2 3.1 3 1 1 4 4 4 0 Porcine reproductive and respiratory syndrome virus 2b TCTP PF00838.17 CBY20818.1 - 4.5e-59 199.5 0.0 5e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein RIBIOP_C PF04950.12 CBY20820.1 - 4.3e-105 351.3 0.1 8.4e-105 350.4 0.1 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CBY20820.1 - 2.7e-05 24.2 0.1 0.0002 21.4 0.1 2.3 1 1 0 1 1 1 1 AARP2CN (NUC121) domain Pes-10 PF07149.11 CBY20820.1 - 1.6 7.7 8.4 2.4 7.1 8.4 1.2 1 0 0 1 1 1 0 Pes-10 CH_2 PF06294.11 CBY20821.1 - 2.7e-29 101.1 0.1 6.3e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBY20821.1 - 3.6e-14 52.3 0.0 6.9e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 CBY20821.1 - 0.0075 16.4 0.6 0.027 14.6 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain TPD52 PF04201.15 CBY20821.1 - 0.12 11.9 3.8 0.3 10.7 3.8 1.6 1 0 0 1 1 1 0 Tumour protein D52 family PKcGMP_CC PF16808.5 CBY20821.1 - 0.13 12.2 4.4 0.36 10.7 4.4 1.9 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CH_2 PF06294.11 CBY20822.1 - 2.5e-11 43.5 0.0 6.7e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBY20822.1 - 7.3e-06 25.7 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain WD40 PF00400.32 CBY20823.1 - 8.7e-32 108.7 12.3 3.9e-08 33.8 0.0 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20823.1 - 2.6e-16 59.7 2.7 6.1e-06 26.4 0.3 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY20823.1 - 9.5e-10 38.7 0.1 0.0024 17.8 0.0 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 CBY20823.1 - 0.037 12.0 1.0 0.1 10.6 1.0 1.6 1 1 0 1 1 1 0 IKI3 family PRP21_like_P PF12230.8 CBY20824.1 - 3.1e-43 148.2 9.2 6.2e-43 147.2 9.2 1.5 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CBY20824.1 - 2.9e-39 132.8 6.1 1.1e-19 70.2 0.5 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 CBY20824.1 - 1.8e-11 43.6 0.0 4.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CBY20824.1 - 0.00036 20.9 0.1 0.0013 19.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain Toprim_Crpt PF13342.6 CBY20824.1 - 0.068 13.2 0.4 15 5.6 0.1 2.5 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase DUF1981 PF09324.10 CBY20825.1 - 0.021 14.6 0.5 0.46 10.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) V-set PF07686.17 CBY20825.1 - 0.035 14.3 0.2 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin V-set domain HEAT PF02985.22 CBY20826.1 - 0.0017 18.5 0.0 0.043 14.1 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat Arm_2 PF04826.13 CBY20826.1 - 0.0049 16.4 1.8 0.0049 16.4 1.8 2.0 1 1 0 1 1 1 1 Armadillo-like DUF383 PF04063.14 CBY20826.1 - 0.03 14.0 0.7 0.068 12.8 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF383) Sel1 PF08238.12 CBY20827.1 - 0.029 15.0 0.0 0.19 12.5 0.0 2.5 3 0 0 3 3 3 0 Sel1 repeat Hepar_II_III_N PF16889.5 CBY20827.1 - 0.074 12.3 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Heparinase II/III N-terminus LRR_8 PF13855.6 CBY20829.1 - 1.3e-33 114.6 24.7 3.6e-12 45.8 8.6 5.6 3 1 3 6 6 6 5 Leucine rich repeat LRR_5 PF13306.6 CBY20829.1 - 2.2e-16 60.0 11.8 2.7e-11 43.5 0.2 2.7 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 CBY20829.1 - 5e-11 43.1 0.2 1.1e-10 41.9 0.2 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.7 CBY20829.1 - 9.5e-09 35.4 27.6 0.00022 21.5 4.5 6.2 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY20829.1 - 2.5e-07 30.4 6.6 0.076 12.5 4.9 3.3 1 1 2 3 3 3 3 Leucine-rich repeat I-set PF07679.16 CBY20829.1 - 3.5e-07 30.2 0.2 1.4e-06 28.3 0.2 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY20829.1 - 7.2e-06 26.3 0.1 1.7e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CBY20829.1 - 1.5e-05 25.1 0.1 3.4e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_4 PF16680.5 CBY20829.1 - 0.0027 17.9 0.0 0.0065 16.7 0.0 1.6 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 CBY20829.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin V-set domain RNA_pol_Rpb2_2 PF04561.14 CBY20831.1 - 0.029 14.0 0.1 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 SIR2 PF02146.17 CBY20832.1 - 2.1e-35 122.2 0.1 9.2e-35 120.2 0.0 2.1 2 0 0 2 2 2 1 Sir2 family Sfi1 PF08457.10 CBY20832.1 - 1.8e-12 46.6 79.5 4.9e-05 22.1 7.6 5.6 1 1 6 7 7 7 7 Sfi1 spindle body protein DUF1168 PF06658.12 CBY20833.1 - 1.2e-30 106.1 22.6 2.2e-30 105.3 22.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DDHD PF02862.17 CBY20833.1 - 0.093 12.9 6.4 0.13 12.4 6.4 1.2 1 0 0 1 1 1 0 DDHD domain Dsh_C PF12316.8 CBY20833.1 - 0.15 12.4 5.3 0.2 12.1 5.3 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Spore_coat_CotO PF14153.6 CBY20833.1 - 0.38 10.7 18.3 0.19 11.6 16.0 1.7 2 0 0 2 2 2 0 Spore coat protein CotO SAPS PF04499.15 CBY20833.1 - 0.56 8.9 13.9 0.77 8.5 13.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 CBY20833.1 - 0.95 7.3 6.0 0.96 7.3 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CBY20833.1 - 1.7 8.4 15.4 2.6 7.8 15.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CBY20833.1 - 1.8 5.6 6.3 1.8 5.6 6.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2981 PF11200.8 CBY20833.1 - 1.9 8.2 4.4 1.9 8.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Hid1 PF12722.7 CBY20833.1 - 2.1 6.3 8.9 2.2 6.3 8.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.12 CBY20833.1 - 2.4 6.0 8.8 3.8 5.4 8.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4746 PF15928.5 CBY20833.1 - 4.8 6.5 16.4 8.1 5.8 16.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4407 PF14362.6 CBY20833.1 - 8.9 5.6 10.9 11 5.2 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_2 PF13639.6 CBY20835.1 - 5.8e-10 39.3 7.2 1.1e-09 38.5 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY20835.1 - 1.4e-07 31.4 3.1 2.6e-07 30.6 2.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY20835.1 - 1.9e-07 30.9 7.6 5.3e-07 29.4 7.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY20835.1 - 3.3e-07 30.0 9.0 6.9e-07 29.0 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY20835.1 - 4e-07 29.9 7.6 8.7e-07 28.8 7.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBY20835.1 - 7.7e-06 26.1 5.4 2.3e-05 24.6 5.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBY20835.1 - 1.2e-05 25.1 5.9 2.8e-05 23.8 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY20835.1 - 1.2e-05 25.3 4.0 1.2e-05 25.3 4.0 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CBY20835.1 - 1.6e-05 24.9 2.3 3e-05 24.0 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CBY20835.1 - 5.5e-05 22.9 6.4 0.00011 21.9 6.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CBY20835.1 - 0.00066 19.5 2.9 0.00066 19.5 2.9 1.8 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 CBY20835.1 - 0.0043 16.7 5.3 0.0095 15.5 5.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBY20835.1 - 0.007 16.2 10.6 0.023 14.6 10.7 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 CBY20835.1 - 0.21 11.7 9.6 0.92 9.7 9.5 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_11 PF17123.5 CBY20835.1 - 0.23 11.3 2.0 0.52 10.1 2.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger FlxA PF14282.6 CBY20835.1 - 2.6 8.1 31.1 2.4 8.2 6.3 4.1 2 1 2 4 4 4 0 FlxA-like protein HALZ PF02183.18 CBY20835.1 - 8.1 6.8 33.4 1.5 9.1 0.6 6.0 6 2 0 6 6 6 0 Homeobox associated leucine zipper LMBR1 PF04791.16 CBY20835.1 - 9.2 5.0 16.1 13 4.5 16.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein HEAT_EZ PF13513.6 CBY20836.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 HEAT-like repeat Troponin PF00992.20 CBY20837.1 - 1.6e-37 128.8 6.3 1.9e-37 128.6 6.3 1.1 1 0 0 1 1 1 1 Troponin Maelstrom PF13017.6 CBY20837.1 - 0.0025 17.5 0.3 0.0031 17.2 0.3 1.1 1 0 0 1 1 1 1 piRNA pathway germ-plasm component SAP PF02037.27 CBY20837.1 - 0.0027 17.4 2.5 0.45 10.3 0.0 3.4 3 0 0 3 3 3 2 SAP domain DUF4600 PF15372.6 CBY20837.1 - 0.02 15.3 2.9 0.063 13.7 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) GCN5L1 PF06320.13 CBY20837.1 - 0.025 14.7 0.3 0.19 11.9 0.1 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Jnk-SapK_ap_N PF09744.9 CBY20837.1 - 0.063 13.5 2.1 0.13 12.5 2.1 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 STAT_alpha PF01017.20 CBY20837.1 - 0.072 13.0 0.2 0.072 13.0 0.2 1.5 2 0 0 2 2 2 0 STAT protein, all-alpha domain SLATT_fungal PF18142.1 CBY20837.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Phospholip_A2_1 PF00068.19 CBY20839.1 - 1.1e-17 64.5 8.3 2.2e-17 63.5 8.3 1.5 1 0 0 1 1 1 1 Phospholipase A2 C2 PF00168.30 CBY20840.1 - 6.6e-17 61.7 0.0 1.6e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 CBY20840.1 - 1.3e-07 31.3 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain RNase_PH PF01138.21 CBY20841.1 - 1.7e-13 51.2 0.0 3.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Phospholip_A2_1 PF00068.19 CBY20842.1 - 1.7e-18 67.1 6.3 1.7e-18 67.1 6.3 1.5 2 0 0 2 2 2 1 Phospholipase A2 zf-TAZ PF02135.16 CBY20844.1 - 4.3e-09 36.7 16.8 5.8e-09 36.3 16.8 1.2 1 0 0 1 1 1 1 TAZ zinc finger Pkinase PF00069.25 CBY20845.1 - 1.3e-59 201.7 0.0 2.4e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CBY20845.1 - 1.3e-29 102.1 0.0 5.7e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY20845.1 - 2.9e-27 95.6 0.0 4.8e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY20845.1 - 6.6e-06 25.6 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY20845.1 - 0.00015 21.8 0.1 0.00023 21.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY20845.1 - 0.00046 19.1 0.1 0.00083 18.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase TSC22 PF01166.18 CBY20845.1 - 0.00066 19.9 0.5 0.0017 18.6 0.5 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family Choline_kinase PF01633.20 CBY20845.1 - 0.013 15.1 0.1 0.055 13.0 0.1 2.1 2 1 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 CBY20845.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3783 PF12646.7 CBY20845.1 - 0.19 11.7 2.1 0.97 9.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) YabA PF06156.13 CBY20845.1 - 0.2 12.3 0.5 0.7 10.6 0.2 2.0 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 CBY20845.1 - 0.25 11.5 1.3 0.59 10.3 1.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor Ank_2 PF12796.7 CBY20847.1 - 7.3e-22 77.8 10.3 5.3e-11 42.9 2.4 2.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY20847.1 - 4.2e-16 59.1 0.2 4.5e-05 23.9 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY20847.1 - 1.3e-13 49.7 0.2 0.0068 16.8 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CBY20847.1 - 6.1e-12 45.5 0.3 1.3e-07 31.8 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY20847.1 - 6.6e-10 39.0 1.2 0.0011 19.4 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat VWA_3_C PF18571.1 CBY20847.1 - 0.0011 18.8 0.5 0.41 10.5 0.1 2.6 2 0 0 2 2 2 2 von Willebrand factor type A C-terminal domain DUF1843 PF08898.10 CBY20847.1 - 0.0079 16.7 0.5 6 7.4 0.2 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF1843) VHS PF00790.19 CBY20848.1 - 3.5e-29 101.5 0.3 1.3e-28 99.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain SH3_9 PF14604.6 CBY20848.1 - 2.2e-17 62.6 0.0 3.9e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY20848.1 - 5.4e-15 54.7 0.1 1.1e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY20848.1 - 2.2e-10 40.0 0.0 6e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain OCRE PF17780.1 CBY20849.1 - 1.9e-15 56.6 2.4 5.4e-15 55.2 2.4 1.8 1 0 0 1 1 1 1 OCRE domain RRM_1 PF00076.22 CBY20849.1 - 5.3e-07 29.4 0.0 6.5e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAFII55_N PF04658.13 CBY20849.1 - 1.4 8.6 5.0 0.19 11.4 0.7 1.7 2 0 0 2 2 2 0 TAFII55 protein conserved region G-patch PF01585.23 CBY20850.1 - 5.6e-18 64.6 2.5 9.9e-18 63.8 2.5 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBY20850.1 - 8.4e-06 25.8 4.4 1.4e-05 25.0 2.6 2.1 1 1 1 2 2 2 1 G-patch domain RED_N PF07808.13 CBY20850.1 - 0.046 13.3 0.2 0.077 12.6 0.2 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region Pkinase PF00069.25 CBY20851.1 - 9.6e-68 228.4 0.0 1.2e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20851.1 - 1.4e-38 132.6 0.0 2.4e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY20851.1 - 0.0018 17.3 0.7 0.0025 16.8 0.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY20851.1 - 0.0029 17.0 0.0 0.0062 15.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CBY20851.1 - 0.0033 17.4 0.3 0.024 14.6 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CBY20851.1 - 0.01 15.4 0.1 0.036 13.7 0.1 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CBY20851.1 - 0.012 15.0 0.3 0.02 14.3 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.24 CBY20852.1 - 1.1e-137 459.7 5.1 1.2e-137 459.5 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRN3 PF05327.11 CBY20853.1 - 8e-08 31.3 0.0 8.5e-08 31.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 RRN3 PF05327.11 CBY20854.1 - 2.8e-52 178.1 8.6 4e-52 177.5 8.3 1.3 1 1 1 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 MFS_1 PF07690.16 CBY20855.1 - 7.4e-21 74.5 44.0 1.1e-20 73.9 44.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 CBY20855.1 - 0.026 13.0 5.4 0.0061 15.0 1.6 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Rep_fac_C PF08542.11 CBY20856.1 - 1.1e-20 73.8 0.1 4e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBY20856.1 - 5.8e-15 55.4 0.1 2.1e-12 47.1 0.2 2.4 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 CBY20856.1 - 6.6e-14 52.5 0.1 1.1e-13 51.8 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CBY20856.1 - 4.8e-08 33.0 0.1 1e-07 32.0 0.0 1.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CBY20856.1 - 5.8e-08 32.9 0.0 2.5e-07 30.8 0.0 1.9 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CBY20856.1 - 6.8e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY20856.1 - 1.9e-05 25.0 0.2 0.012 15.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY20856.1 - 1.9e-05 25.1 0.0 0.0011 19.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 CBY20856.1 - 8.9e-05 22.0 0.0 0.0016 17.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CBY20856.1 - 0.00026 21.4 0.1 0.00062 20.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY20856.1 - 0.00028 20.7 0.0 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 CBY20856.1 - 0.00046 19.7 0.0 0.62 9.4 0.0 2.3 1 1 0 2 2 2 2 Bacterial TniB protein RuvB_N PF05496.12 CBY20856.1 - 0.00058 19.6 0.0 0.0026 17.5 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 CBY20856.1 - 0.00069 19.5 0.1 0.001 19.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CBY20856.1 - 0.00076 19.1 0.0 0.0024 17.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CBY20856.1 - 0.0012 19.1 0.0 0.0039 17.5 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_5 PF07728.14 CBY20856.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CBY20856.1 - 0.0018 18.8 0.0 0.0075 16.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 CBY20856.1 - 0.0023 18.5 0.0 0.0046 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CBY20856.1 - 0.004 17.0 0.3 0.44 10.3 0.0 2.8 1 1 2 3 3 3 1 DEAD/DEAH box helicase AAA_28 PF13521.6 CBY20856.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY20856.1 - 0.023 14.4 0.1 0.065 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY20856.1 - 0.031 14.6 0.0 0.094 13.1 0.0 1.9 1 1 0 1 1 1 0 RNA helicase DNA_pol3_delta PF06144.13 CBY20856.1 - 0.034 13.9 0.2 0.059 13.1 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_7 PF12775.7 CBY20856.1 - 0.035 13.6 0.0 0.074 12.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region APG17 PF04108.12 CBY20856.1 - 0.037 13.1 0.1 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 NTPase_1 PF03266.15 CBY20856.1 - 0.054 13.4 0.4 0.38 10.6 0.1 2.3 1 1 1 2 2 2 0 NTPase AAA_3 PF07726.11 CBY20856.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DDOST_48kD PF03345.14 CBY20857.1 - 2.9e-111 372.3 4.1 3.4e-111 372.0 4.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2194 PF09960.9 CBY20857.1 - 7.7e-08 31.2 0.4 1.4e-07 30.3 0.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) zf-C3HC4_3 PF13920.6 CBY20858.1 - 1.2e-05 25.1 13.0 1.2e-05 25.1 13.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY20858.1 - 0.0022 17.8 15.5 0.0085 15.9 15.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY20858.1 - 0.0023 17.7 16.4 0.0069 16.2 16.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY20858.1 - 0.012 15.9 15.7 0.012 15.9 15.7 2.1 2 0 0 2 2 2 0 Ring finger domain HrpB7 PF09486.10 CBY20858.1 - 0.017 15.5 0.9 0.029 14.7 0.9 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) zf-RING_6 PF14835.6 CBY20858.1 - 0.023 14.6 7.7 0.023 14.6 7.7 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein KxDL PF10241.9 CBY20858.1 - 0.023 15.0 13.2 0.24 11.7 1.3 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein HAP1_N PF04849.13 CBY20858.1 - 0.14 11.3 17.9 0.19 10.9 17.9 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region zf-C3HC4_4 PF15227.6 CBY20858.1 - 0.18 12.0 17.2 0.6 10.3 17.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ribonuc_2-5A PF06479.12 CBY20858.1 - 0.21 11.7 6.6 0.35 11.1 6.6 1.3 1 0 0 1 1 1 0 Ribonuclease 2-5A CALCOCO1 PF07888.11 CBY20858.1 - 0.32 9.8 18.0 0.39 9.5 18.0 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BRE1 PF08647.11 CBY20858.1 - 0.34 11.0 25.7 0.15 12.2 12.0 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Exonuc_VII_L PF02601.15 CBY20858.1 - 0.86 9.1 6.0 0.95 9.0 6.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 CBY20858.1 - 7.5 5.0 18.1 10 4.6 18.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-RING_UBOX PF13445.6 CBY20858.1 - 9.1 6.4 15.6 7.8 6.6 13.2 2.2 2 1 0 2 2 2 0 RING-type zinc-finger OCRE PF17780.1 CBY20859.1 - 9.5e-07 28.8 0.2 1.8e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 OCRE domain Yop-YscD_cpl PF16697.5 CBY20859.1 - 0.044 14.1 0.2 1.4 9.2 0.1 2.4 2 1 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Astro_capsid_p PF12226.8 CBY20859.1 - 0.41 9.7 3.2 0.61 9.2 3.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein LIAS_N PF16881.5 CBY20860.1 - 9.4e-26 90.4 0.0 2.8e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CBY20860.1 - 2.8e-14 53.9 0.0 4.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_L4 PF00573.22 CBY20861.1 - 1e-37 129.7 1.1 1.6e-37 129.1 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CBY20861.1 - 7.4e-26 90.0 4.8 7.4e-26 90.0 4.8 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PGDH_C PF16896.5 CBY20861.1 - 0.024 14.6 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term Ribosomal_S30 PF04758.14 CBY20862.1 - 2.7e-29 101.1 8.5 3.5e-29 100.8 8.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 BTB_2 PF02214.22 CBY20863.1 - 3.6e-19 68.9 0.1 6.7e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CBY20863.1 - 3.2e-05 24.1 0.1 7.1e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CBY20863.1 - 0.00014 21.9 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Proteasome PF00227.26 CBY20864.1 - 1.4e-33 116.0 0.0 1.6e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Kelch_1 PF01344.25 CBY20865.1 - 2e-78 257.8 11.6 5.1e-15 54.8 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CBY20865.1 - 6.2e-42 140.6 2.0 3e-08 33.6 0.0 6.6 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CBY20865.1 - 2.9e-29 99.9 5.3 7.2e-06 25.8 0.1 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CBY20865.1 - 1.3e-24 85.9 0.0 0.0011 18.9 0.0 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY20865.1 - 1.7e-22 79.2 3.6 1.3e-06 28.5 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain BTB PF00651.31 CBY20865.1 - 8.6e-19 67.8 0.0 1.7e-17 63.6 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 CBY20865.1 - 2.3e-16 59.8 0.0 1.1e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CBY20865.1 - 4.4e-09 36.1 2.7 1 9.4 0.0 6.2 6 0 0 6 6 6 3 Kelch motif STD1 PF17235.2 CBY20865.1 - 0.003 17.2 0.0 0.84 9.2 0.1 2.4 1 1 1 2 2 2 2 STD1/MTH1 eIF2_C PF09173.11 CBY20866.1 - 1.9e-32 111.3 0.2 4.4e-32 110.2 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CBY20866.1 - 3.7e-27 95.1 0.2 5.6e-27 94.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CBY20866.1 - 1e-05 25.8 0.1 2.5e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY20866.1 - 5.3e-05 23.3 0.2 0.0011 19.0 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBY20866.1 - 0.0003 20.6 1.0 0.085 12.6 0.1 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 CBY20866.1 - 0.0029 17.5 0.2 0.086 12.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CBY20866.1 - 0.022 14.8 0.1 0.051 13.6 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 CBY20866.1 - 0.023 14.8 0.4 0.16 12.1 0.4 2.1 1 1 0 1 1 1 0 Dynamin family TFIIF_beta PF02270.15 CBY20868.1 - 1.6e-23 82.6 1.0 2.8e-23 81.8 1.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CBY20868.1 - 1.2e-10 42.2 1.0 4.1e-10 40.5 0.8 2.3 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus SIR4_SID PF16991.5 CBY20868.1 - 0.38 10.8 2.5 0.43 10.6 0.6 2.2 2 1 0 2 2 2 0 Sir4 SID domain RRM_1 PF00076.22 CBY20870.1 - 1.2e-18 66.7 0.1 2.5e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY20870.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBY20870.1 - 0.047 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_3 PF01494.19 CBY20872.1 - 7.7e-21 74.7 0.0 1.1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CBY20872.1 - 0.00017 22.0 0.2 0.0061 17.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY20872.1 - 0.00054 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CBY20872.1 - 0.00076 18.5 1.1 0.7 8.7 0.8 2.4 2 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 CBY20872.1 - 0.00087 18.6 0.1 0.02 14.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 CBY20872.1 - 0.0018 17.4 0.0 0.017 14.2 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 CBY20872.1 - 0.015 14.9 0.0 2.2 7.8 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 CBY20872.1 - 0.091 12.4 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CBY20872.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2935 PF11155.8 CBY20873.1 - 0.017 15.4 0.1 0.026 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Phage_lysis PF03245.13 CBY20873.1 - 0.23 11.6 4.9 0.39 10.9 4.9 1.3 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein EDR1 PF14381.6 CBY20874.1 - 1.9e-29 102.8 0.2 1.5e-28 99.9 0.0 2.2 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.6 CBY20874.1 - 1.2e-12 48.0 0.2 0.002 18.4 0.0 5.6 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 CBY20874.1 - 1.6e-11 43.4 4.1 0.56 10.6 0.1 6.8 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.20 CBY20874.1 - 3e-09 36.0 9.8 3.7e-06 25.8 0.2 2.4 2 1 0 2 2 2 2 Adaptin N terminal region Arm PF00514.23 CBY20874.1 - 3.6e-08 33.2 8.1 0.051 13.6 0.0 7.1 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CBY20874.1 - 7e-07 29.4 5.8 0.00012 22.2 0.0 3.6 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 CBY20874.1 - 1.6e-05 25.0 3.6 0.086 13.0 0.0 4.8 4 1 1 5 5 5 1 V-ATPase subunit H HEAT_EZ PF13513.6 CBY20874.1 - 0.00018 21.9 7.0 16 6.1 0.0 5.9 5 1 2 7 7 7 0 HEAT-like repeat Atx10homo_assoc PF09759.9 CBY20874.1 - 0.00024 21.1 0.3 0.89 9.6 0.0 4.0 2 1 2 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 CBY20874.1 - 0.00039 20.0 2.4 0.031 13.7 0.1 2.9 3 1 0 3 3 3 1 Armadillo-like Sec7_N PF12783.7 CBY20874.1 - 0.0084 16.0 5.1 5 7.0 0.8 3.5 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal NdhM PF10664.9 CBY20874.1 - 0.033 14.4 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M RTP1_C1 PF10363.9 CBY20874.1 - 0.2 11.9 0.7 4.3 7.6 0.1 3.0 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 C8 PF08742.11 CBY20875.1 - 1e-16 61.1 4.0 1e-16 61.1 4.0 2.2 2 0 0 2 2 2 1 C8 domain TIL PF01826.17 CBY20875.1 - 5.7e-09 36.1 16.6 5.7e-09 36.1 16.6 3.3 3 0 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Galactosyl_T PF01762.21 CBY20880.1 - 3.1e-19 69.6 0.0 4.4e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Tektin PF03148.14 CBY20881.1 - 1.1e-136 455.6 45.5 1.4e-96 323.6 18.8 3.2 2 1 0 2 2 2 2 Tektin family LPD11 PF18824.1 CBY20881.1 - 0.0065 16.5 0.0 7.8 6.7 0.0 2.9 2 0 0 2 2 2 2 Large polyvalent protein-associated domain 11 EspB PF05802.11 CBY20881.1 - 0.065 13.2 0.6 18 5.2 0.1 2.9 2 0 0 2 2 2 0 Enterobacterial EspB protein dCache_2 PF08269.11 CBY20881.1 - 0.15 11.2 9.6 1.2 8.3 0.1 3.3 3 0 0 3 3 3 0 Cache domain GTP_EFTU_D4 PF14578.6 CBY20881.1 - 0.2 11.6 0.1 51 3.9 0.0 3.0 2 1 1 3 3 3 0 Elongation factor Tu domain 4 Syntaxin-6_N PF09177.11 CBY20881.1 - 2.2 8.9 23.5 0.1 13.2 1.5 6.0 4 2 1 5 5 5 0 Syntaxin 6, N-terminal Prp19 PF08606.11 CBY20881.1 - 6 6.9 11.1 25 5.0 0.5 4.6 3 1 1 4 4 4 0 Prp19/Pso4-like BSD PF03909.17 CBY20882.1 - 1.3e-16 60.3 8.1 2.2e-16 59.6 0.0 3.3 3 0 0 3 3 3 1 BSD domain SLATT_fungal PF18142.1 CBY20882.1 - 0.71 9.9 3.5 10 6.1 0.1 2.9 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain GP41 PF00517.17 CBY20882.1 - 1.7 8.5 9.6 0.53 10.2 4.0 2.5 2 0 0 2 2 2 0 Retroviral envelope protein Focal_AT PF03623.13 CBY20882.1 - 6 6.9 11.0 1.7 8.6 1.6 3.1 2 1 1 3 3 3 0 Focal adhesion targeting region Kelch_1 PF01344.25 CBY20883.1 - 3.1e-45 151.5 8.0 2.1e-12 46.4 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBY20883.1 - 1.4e-32 110.9 6.4 2.3e-10 40.4 0.0 7.2 2 2 4 6 6 6 6 Kelch motif BTB PF00651.31 CBY20883.1 - 9.4e-26 90.2 1.9 1.2e-25 89.9 0.2 2.1 3 0 0 3 3 3 1 BTB/POZ domain Kelch_2 PF07646.15 CBY20883.1 - 1.3e-20 72.5 9.6 9e-05 22.3 0.0 6.5 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CBY20883.1 - 7e-19 67.6 1.8 1.7e-06 28.2 0.0 6.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY20883.1 - 6.3e-16 58.1 5.9 1e-05 25.4 0.1 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY20883.1 - 8.4e-14 51.2 7.7 0.021 14.8 0.0 5.9 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 CBY20883.1 - 3.6e-12 46.3 0.1 9.7e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Ank_4 PF13637.6 CBY20884.1 - 2.2e-06 28.1 0.0 0.00035 21.1 0.0 2.6 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY20884.1 - 7e-05 23.1 0.1 0.015 15.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CBY20884.1 - 0.00014 22.0 0.0 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY20884.1 - 0.0011 19.6 0.1 0.0033 18.0 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF1211 PF06736.11 CBY20884.1 - 0.032 14.7 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) bZIP_1 PF00170.21 CBY20885.1 - 0.0002 21.4 4.1 0.00021 21.3 3.0 1.5 1 1 1 2 2 2 1 bZIP transcription factor ZapB PF06005.12 CBY20885.1 - 0.0015 19.0 1.4 0.0018 18.6 1.4 1.2 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 CBY20885.1 - 0.0039 16.9 1.4 0.0055 16.4 1.4 1.2 1 0 0 1 1 1 1 Septum formation initiator DUF1474 PF07342.11 CBY20885.1 - 0.0095 16.4 0.6 0.01 16.4 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1474) NRBF2 PF08961.10 CBY20885.1 - 0.03 13.9 1.4 0.037 13.6 1.4 1.3 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Tfb4 PF03850.14 CBY20885.1 - 0.036 13.5 0.2 0.037 13.5 0.2 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 Arb2 PF09757.9 CBY20885.1 - 0.051 12.7 0.2 0.056 12.6 0.2 1.0 1 0 0 1 1 1 0 Arb2 domain PRKG1_interact PF15898.5 CBY20885.1 - 0.084 13.8 5.2 3.6 8.5 0.2 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain T4bSS_IcmS PF12608.8 CBY20885.1 - 0.088 13.1 0.3 0.1 12.9 0.3 1.2 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment Aldo_ket_red PF00248.21 CBY20886.1 - 1.5e-47 162.2 0.0 2.2e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Haspin_kinase PF12330.8 CBY20886.1 - 0.029 13.3 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Ank_2 PF12796.7 CBY20887.1 - 4.1e-13 49.7 0.0 1.8e-05 25.2 0.0 2.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY20887.1 - 8.2e-12 45.4 0.0 0.0027 18.2 0.0 4.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY20887.1 - 1.6e-07 31.1 0.0 0.2 12.3 0.0 4.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 CBY20887.1 - 3.8e-06 27.1 0.3 0.0044 17.3 0.0 3.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY20887.1 - 0.0021 18.4 0.0 0.95 10.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat FAM53 PF15242.6 CBY20887.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Family of FAM53 Ank_3 PF13606.6 CBY20889.1 - 0.0001 22.4 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 CBY20889.1 - 0.0053 17.0 0.2 0.016 15.5 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY20889.1 - 0.12 12.9 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeat WD40 PF00400.32 CBY20890.1 - 9.3e-35 118.1 19.3 8.1e-09 36.0 1.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20890.1 - 0.0023 18.2 1.4 9 6.7 0.2 4.4 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY20890.1 - 0.037 12.7 1.9 7.6 5.0 0.4 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 AAA PF00004.29 CBY20891.1 - 1.3e-39 135.7 0.0 3.2e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 CBY20891.1 - 8.9e-33 113.7 0.6 2.3e-32 112.4 0.6 1.7 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 CBY20891.1 - 3.6e-13 49.1 0.1 2.5e-12 46.4 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CBY20891.1 - 8.2e-06 26.3 0.6 0.0022 18.4 0.0 3.3 3 1 1 4 4 3 1 AAA ATPase domain AAA_2 PF07724.14 CBY20891.1 - 1e-05 25.7 0.0 9.3e-05 22.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBY20891.1 - 1.2e-05 25.3 0.1 0.00019 21.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBY20891.1 - 6.8e-05 22.7 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CBY20891.1 - 0.00011 21.7 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 CBY20891.1 - 0.00088 19.5 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY20891.1 - 0.001 19.4 0.1 0.012 15.9 0.1 2.6 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 CBY20891.1 - 0.0013 17.9 0.0 0.0033 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CBY20891.1 - 0.0016 18.2 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 CBY20891.1 - 0.0018 17.6 1.6 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBY20891.1 - 0.0024 17.3 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBY20891.1 - 0.0031 18.0 5.1 0.0034 17.9 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CBY20891.1 - 0.0072 16.7 0.0 0.029 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBY20891.1 - 0.016 15.2 0.0 0.082 12.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain TsaE PF02367.17 CBY20891.1 - 0.017 15.2 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBY20891.1 - 0.039 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBY20891.1 - 0.045 13.4 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Spore_permease PF03845.13 CBY20891.1 - 0.05 12.4 0.1 0.083 11.7 0.1 1.2 1 0 0 1 1 1 0 Spore germination protein AAA_17 PF13207.6 CBY20891.1 - 0.055 13.9 0.0 0.055 13.9 0.0 2.6 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.22 CBY20891.1 - 0.067 13.6 0.0 0.25 11.7 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CBY20891.1 - 0.071 12.8 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBY20891.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.7 3 1 0 3 3 2 0 AAA domain POP1 PF06978.11 CBY20891.1 - 0.45 10.5 6.6 0.078 13.0 2.1 2.0 2 0 0 2 2 1 0 Ribonucleases P/MRP protein subunit POP1 HJURP_mid PF12346.8 CBY20891.1 - 0.92 10.0 4.2 2.3 8.7 4.2 1.6 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat AAA_11 PF13086.6 CBY20891.1 - 1 9.1 0.0 1 9.1 0.0 2.8 3 1 0 3 3 3 0 AAA domain Nic96 PF04097.14 CBY20892.1 - 2.2e-07 29.8 4.4 0.18 10.2 0.3 4.5 2 1 2 4 4 4 3 Nup93/Nic96 TPR_7 PF13176.6 CBY20892.1 - 1.4e-06 27.9 19.0 0.18 11.9 0.1 8.4 7 1 0 7 7 7 2 Tetratricopeptide repeat Clathrin PF00637.20 CBY20892.1 - 1.7e-06 28.0 10.5 0.88 9.4 0.1 6.9 5 2 2 7 7 7 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CBY20892.1 - 0.00015 22.0 2.3 0.0066 16.7 0.4 4.4 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain MIT PF04212.18 CBY20892.1 - 0.0022 18.0 15.1 0.66 10.1 0.4 5.1 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain Coatomer_WDAD PF04053.14 CBY20892.1 - 0.0065 15.6 5.0 0.13 11.2 1.3 3.3 2 1 0 2 2 2 1 Coatomer WD associated region TPR_12 PF13424.6 CBY20892.1 - 0.38 11.1 20.1 15 6.0 0.0 7.6 6 2 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY20892.1 - 0.43 10.5 17.0 12 5.9 1.3 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY20892.1 - 0.6 10.4 33.4 1.7 8.9 1.6 9.5 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY20892.1 - 4.3 7.8 10.1 16 6.0 1.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ADD_ATRX PF17981.1 CBY20893.1 - 3.8e-09 36.3 0.1 3.8e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 Cysteine Rich ADD domain WD40 PF00400.32 CBY20894.1 - 4.6e-07 30.4 0.6 0.066 14.1 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY20894.1 - 4.3e-06 26.9 0.0 0.14 12.4 0.0 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY20894.1 - 0.0096 15.3 1.1 0.043 13.1 1.3 1.8 1 1 1 2 2 2 1 WD40-like domain VID27 PF08553.10 CBY20894.1 - 0.013 14.6 0.1 0.053 12.6 0.0 2.0 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 CBY20894.1 - 0.023 13.8 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region BBS2_Mid PF14783.6 CBY20894.1 - 0.16 12.0 0.1 0.49 10.4 0.0 1.8 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Utp8 PF10395.9 CBY20894.1 - 0.17 10.4 0.0 7.9 4.8 0.0 2.1 2 0 0 2 2 2 0 Utp8 family Flp_N PF03930.14 CBY20896.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus Pkinase_Tyr PF07714.17 CBY20897.1 - 3.6e-50 170.7 0.0 5.1e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY20897.1 - 5.6e-50 170.2 0.0 8.1e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY20897.1 - 6.2e-05 21.9 0.2 0.00016 20.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 CBY20897.1 - 0.00012 21.8 0.6 0.12 12.0 0.0 2.7 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CBY20897.1 - 0.0023 17.6 0.2 0.016 14.8 0.2 2.2 1 1 0 1 1 1 1 RIO1 family zf-C4H2 PF10146.9 CBY20897.1 - 0.28 11.5 5.2 1.7 8.9 5.3 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein bZIP_2 PF07716.15 CBY20898.1 - 0.00014 21.8 11.3 0.00014 21.8 11.3 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY20898.1 - 0.00025 21.1 10.1 0.00025 21.1 10.1 2.3 1 1 1 2 2 2 1 bZIP transcription factor DUF3450 PF11932.8 CBY20898.1 - 0.068 12.5 6.6 0.11 11.8 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.17 CBY20898.1 - 0.15 12.6 10.8 0.18 12.4 9.8 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF883 PF05957.13 CBY20898.1 - 0.3 11.7 2.6 0.76 10.4 2.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YabA PF06156.13 CBY20898.1 - 1.6 9.4 5.4 3.5 8.3 5.0 1.9 1 1 0 1 1 1 0 Initiation control protein YabA CASP_C PF08172.12 CBY20898.1 - 6.4 6.0 15.3 0.33 10.3 2.5 2.2 1 1 1 2 2 2 0 CASP C terminal FlaC_arch PF05377.11 CBY20899.1 - 7.1 7.1 7.4 3.2 8.2 0.9 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 CBY20901.1 - 7.4 6.3 14.6 0.3 10.9 0.1 4.2 5 2 1 7 7 7 0 Phage integrase family bZIP_1 PF00170.21 CBY20902.1 - 8.7e-08 32.2 7.5 8.7e-08 32.2 7.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CBY20902.1 - 7.1e-07 29.2 10.7 7.1e-07 29.2 10.7 1.9 2 0 0 2 2 2 1 Basic region leucine zipper HTH_ABP1_N PF18107.1 CBY20902.1 - 0.028 14.1 0.7 0.067 12.9 0.7 1.6 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain YabA PF06156.13 CBY20902.1 - 2.7 8.7 5.1 4.9 7.8 4.7 1.7 1 1 1 2 2 2 0 Initiation control protein YabA RhoGAP PF00620.27 CBY20903.1 - 7.9e-43 145.9 0.1 2.3e-42 144.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.28 CBY20903.1 - 5.2e-09 35.6 0.0 9.7e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY20903.1 - 6.4e-09 35.5 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY20903.1 - 1.9e-05 24.3 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PriC PF07445.12 CBY20903.1 - 0.00089 19.2 0.3 0.00089 19.2 0.3 3.6 2 1 1 3 3 3 2 Primosomal replication protein priC DUF842 PF05811.13 CBY20903.1 - 0.19 11.5 4.4 0.17 11.6 1.0 2.7 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Prefoldin PF02996.17 CBY20903.1 - 2 8.4 8.9 11 5.9 0.2 4.0 4 0 0 4 4 4 0 Prefoldin subunit BRCT PF00533.26 CBY20905.1 - 4.7e-08 33.3 6.5 9.1e-05 22.8 0.2 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CBY20905.1 - 2e-07 30.8 1.3 1.4e-06 28.1 0.0 3.2 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 CBY20905.1 - 5.6e-07 29.9 1.0 0.0012 19.2 0.2 3.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY20905.1 - 0.049 13.9 0.3 0.049 13.9 0.3 3.2 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain CdhC PF03598.15 CBY20905.1 - 0.12 12.2 0.6 0.29 11.0 0.6 1.6 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Prominin PF05478.11 CBY20905.1 - 0.27 9.2 9.7 0.054 11.4 5.8 1.8 2 0 0 2 2 2 0 Prominin MAGE PF01454.19 CBY20906.1 - 0.00057 19.7 0.3 0.0011 18.8 0.2 1.4 1 1 0 1 1 1 1 MAGE family Tubulin PF00091.25 CBY20907.1 - 6.3e-68 228.9 0.0 8.3e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY20907.1 - 1.9e-47 160.6 0.0 3.1e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY20907.1 - 0.0017 18.0 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pyridox_oxase_2 PF12766.7 CBY20908.1 - 0.083 13.5 0.0 0.2 12.3 0.0 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF1463 PF07316.11 CBY20909.1 - 0.05 13.4 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) DUF3844 PF12955.7 CBY20910.1 - 1.2 9.3 5.5 3.4 7.8 5.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) Es2 PF09751.9 CBY20911.1 - 2.5e-55 189.0 12.4 2.5e-55 189.0 12.4 2.0 1 1 1 2 2 2 1 Nuclear protein Es2 PQ-loop PF04193.14 CBY20911.1 - 7.6e-15 54.4 6.0 3.1e-09 36.5 1.9 2.8 2 0 0 2 2 2 2 PQ loop repeat ETC_C1_NDUFA4 PF04800.12 CBY20912.1 - 2.5e-30 104.6 2.4 3.7e-30 104.0 2.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ribosomal_60s PF00428.19 CBY20913.1 - 3.6e-23 82.0 2.3 4.2e-23 81.8 2.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Anophelin PF10731.9 CBY20913.1 - 0.052 13.4 0.2 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito TPR_1 PF00515.28 CBY20914.1 - 2.6e-17 61.8 10.0 0.00034 20.3 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY20914.1 - 1.3e-15 56.1 16.2 0.0086 16.1 0.1 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 CBY20914.1 - 1.8e-10 41.2 3.8 0.04 14.4 0.0 5.1 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY20914.1 - 1.3e-08 35.4 7.1 3.9e-06 27.4 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY20914.1 - 2.6e-08 34.0 7.7 0.17 12.2 0.5 5.4 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY20914.1 - 2.8e-08 33.9 6.0 2.5 9.2 0.1 6.4 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY20914.1 - 9.8e-07 28.4 6.0 0.01 15.5 0.0 5.4 5 0 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 CBY20914.1 - 3.1e-05 23.7 7.2 0.54 10.4 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY20914.1 - 0.00024 21.2 6.0 0.17 12.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY20914.1 - 0.00031 20.1 0.0 0.4 9.8 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY20914.1 - 0.0031 17.6 13.0 4.1 7.8 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY20914.1 - 0.0046 17.5 6.5 4.8 8.0 0.0 5.3 7 0 0 7 7 4 1 Tetratricopeptide repeat MIT PF04212.18 CBY20914.1 - 0.0057 16.7 5.7 2.2 8.4 0.4 4.3 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CBY20914.1 - 0.055 13.4 6.0 32 4.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY20914.1 - 0.083 13.3 0.1 29 5.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBY20914.1 - 0.15 11.5 3.1 14 5.3 0.1 3.8 3 0 0 3 3 3 0 SHNi-TPR SnAPC_2_like PF11035.8 CBY20915.1 - 8.5e-07 29.4 0.2 8.5e-07 29.4 0.2 3.7 2 2 0 3 3 3 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Radical_SAM_N PF08497.10 CBY20915.1 - 0.6 9.3 4.3 0.14 11.4 0.2 1.8 2 0 0 2 2 2 0 Radical SAM N-terminal KAP PF05804.12 CBY20916.1 - 1.6e-214 714.1 10.2 2.2e-214 713.7 10.2 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Rcd1 PF04078.13 CBY20916.1 - 0.0033 16.8 0.2 0.0096 15.2 0.0 1.9 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like Arm PF00514.23 CBY20916.1 - 0.035 14.2 4.9 0.6 10.2 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat SCO1-SenC PF02630.14 CBY20916.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 SCO1/SenC MKLP1_Arf_bdg PF16540.5 CBY20917.1 - 3.4e-13 49.6 13.1 1.9e-11 43.9 6.0 3.5 2 1 0 2 2 2 1 Arf6-interacting domain of mitotic kinesin-like protein 1 APG6_N PF17675.1 CBY20917.1 - 0.017 15.6 13.3 0.017 15.6 13.3 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 CBY20917.1 - 4.8 5.0 15.6 9.2 4.0 15.6 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 CBY20918.1 - 3.6e-54 183.9 0.0 4.5e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20918.1 - 4.7e-24 85.1 0.0 7.1e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY20918.1 - 0.00028 20.3 0.1 0.00099 18.5 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY20918.1 - 0.00043 19.2 0.0 0.00066 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY20918.1 - 0.0095 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY20918.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Argos PF11581.8 CBY20918.1 - 0.061 13.4 0.4 0.11 12.6 0.4 1.3 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos DSPc PF00782.20 CBY20919.1 - 1e-12 48.0 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY20919.1 - 0.016 15.3 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBY20919.1 - 0.026 14.1 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Acyl-CoA_dh_1 PF00441.24 CBY20920.1 - 2.7e-40 138.0 1.3 4.4e-40 137.3 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY20920.1 - 5.8e-25 87.3 0.0 1.1e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY20920.1 - 9.2e-24 84.3 0.0 1.9e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY20920.1 - 6.2e-16 58.9 0.4 6.2e-16 58.9 0.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CBY20920.1 - 0.055 14.0 0.2 0.19 12.3 0.0 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Pkinase PF00069.25 CBY20921.1 - 1.2e-53 182.2 0.0 1.5e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20921.1 - 1.5e-23 83.4 0.0 2.2e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY20921.1 - 0.0003 20.2 0.1 0.0012 18.3 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY20921.1 - 0.00082 18.3 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY20921.1 - 0.0053 16.1 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY20921.1 - 0.0096 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Argos PF11581.8 CBY20921.1 - 0.039 14.0 0.4 0.066 13.2 0.4 1.3 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos DSPc PF00782.20 CBY20922.1 - 3.1e-13 49.7 0.0 4.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY20922.1 - 0.0037 17.4 0.0 0.0047 17.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBY20922.1 - 0.023 14.3 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY20922.1 - 0.093 12.7 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Acyl-CoA_dh_1 PF00441.24 CBY20923.1 - 1.5e-40 138.9 1.3 2.2e-40 138.3 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY20923.1 - 3.5e-25 88.0 0.0 6.3e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY20923.1 - 5.2e-24 85.1 0.0 1e-23 84.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY20923.1 - 2.1e-16 60.4 0.4 3.3e-16 59.8 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CBY20923.1 - 0.068 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal dsrm PF00035.26 CBY20924.1 - 6.4e-05 23.6 3.5 6.4e-05 23.6 3.5 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif CFC PF09443.10 CBY20924.1 - 0.29 11.0 3.0 0.68 9.8 3.0 1.5 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Nucleoplasmin PF03066.15 CBY20925.1 - 1.7e-17 63.7 0.0 4.6e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain Nop53 PF07767.11 CBY20925.1 - 0.0024 17.4 19.8 0.0031 17.0 19.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Mif2_N PF15624.6 CBY20925.1 - 0.0042 17.8 5.6 0.0079 16.9 5.6 1.4 1 0 0 1 1 1 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CDC45 PF02724.14 CBY20925.1 - 1.9 6.7 9.9 2.4 6.4 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 CBY20925.1 - 3.4 7.6 21.5 6 6.8 21.5 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Hid1 PF12722.7 CBY20925.1 - 5.7 4.9 8.0 6.9 4.7 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRM_1 PF00076.22 CBY20926.1 - 1.4e-31 108.1 0.7 4.1e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 CBY20926.1 - 9.3e-19 67.4 0.1 4.7e-18 65.1 0.1 2.3 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_occluded PF16842.5 CBY20926.1 - 1.2e-06 28.2 0.0 9.2e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CBY20926.1 - 1.4e-05 24.6 0.0 0.00027 20.5 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY20926.1 - 4.3e-05 23.6 0.0 0.00058 19.9 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CBY20926.1 - 0.00048 20.1 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY20926.1 - 0.0083 16.2 8.8 0.29 11.2 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif FAM110_N PF14161.6 CBY20926.1 - 0.11 12.7 0.8 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 Centrosome-associated N terminus WW PF00397.26 CBY20927.1 - 2e-09 37.4 0.0 1.8e-06 27.9 0.0 3.5 3 0 0 3 3 3 2 WW domain DNA_pol_B PF00136.21 CBY20928.1 - 1.4e-65 221.9 0.0 2.5e-65 221.0 0.0 1.3 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBY20928.1 - 4.7e-08 32.5 0.4 7.3e-08 31.9 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain 6PF2K PF01591.18 CBY20929.1 - 4.1e-81 271.5 0.5 6.1e-81 271.0 0.5 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CBY20929.1 - 4.2e-39 134.2 0.0 7.2e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 CBY20929.1 - 0.00023 20.7 0.0 0.00054 19.5 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CBY20929.1 - 0.0005 20.2 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY20929.1 - 0.004 17.7 0.0 0.0082 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CBY20929.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Adaptin_N PF01602.20 CBY20930.1 - 3.8e-117 392.0 8.1 5e-117 391.6 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CBY20930.1 - 2.6e-50 170.5 0.1 6.1e-50 169.3 0.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CBY20930.1 - 2.6e-35 121.0 0.0 7.3e-35 119.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CBY20930.1 - 7.7e-18 64.7 1.7 9.5e-08 32.3 0.0 6.1 3 2 4 7 7 7 4 HEAT repeats Cnd1 PF12717.7 CBY20930.1 - 1.9e-13 50.8 14.6 2.5e-05 24.4 0.9 5.1 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBY20930.1 - 6e-05 23.0 2.7 27 5.4 0.0 6.6 5 0 0 5 5 5 0 HEAT repeat DNA_alkylation PF08713.11 CBY20930.1 - 0.0038 17.0 0.1 0.015 15.0 0.1 2.1 2 0 0 2 2 2 1 DNA alkylation repair enzyme HEAT_PBS PF03130.16 CBY20930.1 - 0.0043 17.6 0.1 3.2 8.7 0.1 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 CBY20930.1 - 0.0045 17.4 2.9 0.68 10.5 0.4 5.0 6 1 1 7 7 7 1 HEAT-like repeat Arm PF00514.23 CBY20930.1 - 0.023 14.8 0.2 9.6 6.4 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Acyltransferase PF01553.21 CBY20931.1 - 1.3e-21 76.6 0.0 2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CBY20931.1 - 2.4e-16 59.6 1.8 4.5e-16 58.7 1.8 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus UQ_con PF00179.26 CBY20932.1 - 4.5e-19 68.5 0.0 6.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 CBY20933.1 - 4.9e-20 71.6 0.1 6.3e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY20933.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain RNase_T PF00929.24 CBY20934.1 - 3.9e-11 43.8 0.0 6.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease PA26 PF04636.13 CBY20935.1 - 0.51 9.2 5.1 0.96 8.3 5.1 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RNase_T PF00929.24 CBY20936.1 - 3.6e-13 50.4 0.0 5.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CBY20936.1 - 0.016 14.9 0.0 0.064 13.0 0.0 1.8 1 1 0 1 1 1 0 3'-5' exonuclease SH2 PF00017.24 CBY20939.1 - 1e-19 70.4 0.2 2e-19 69.5 0.2 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 CBY20939.1 - 1.2e-18 66.7 0.4 2.2e-09 37.0 0.1 3.1 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CBY20939.1 - 4.2e-17 61.5 0.3 1.3e-08 34.3 0.0 3.2 3 1 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 CBY20939.1 - 8.6e-12 44.6 0.0 1.2e-05 24.9 0.0 2.8 2 1 0 2 2 2 2 Variant SH3 domain MbtH PF03621.13 CBY20939.1 - 0.16 11.5 1.0 0.26 10.8 0.1 1.8 2 0 0 2 2 2 0 MbtH-like protein SH2 PF00017.24 CBY20940.1 - 9.5e-15 54.5 0.4 2.8e-13 49.8 0.0 2.8 2 1 0 2 2 2 1 SH2 domain SH3_9 PF14604.6 CBY20940.1 - 4e-12 45.8 0.9 2.4e-08 33.7 0.1 2.8 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CBY20940.1 - 2.2e-09 36.8 0.6 0.0033 17.0 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBY20940.1 - 4.7e-06 26.2 0.1 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Forkhead PF00250.18 CBY20943.1 - 2.1e-21 76.0 0.1 4.9e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Metallophos PF00149.28 CBY20944.1 - 5.8e-42 144.5 0.0 7.4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBY20944.1 - 6.6e-20 71.3 0.2 1.3e-19 70.3 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain GAS PF13851.6 CBY20945.1 - 3.3e-05 23.3 10.0 0.0045 16.4 0.6 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Rab5-bind PF09311.11 CBY20945.1 - 0.00037 20.0 6.8 0.00037 20.0 6.8 1.5 1 1 0 1 1 1 1 Rabaptin-like protein HAUS-augmin3 PF14932.6 CBY20945.1 - 0.0013 18.3 3.4 0.0013 18.3 3.4 1.7 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 Tropomyosin_1 PF12718.7 CBY20945.1 - 0.0027 17.9 13.5 0.071 13.3 7.8 2.2 2 0 0 2 2 2 2 Tropomyosin like Acetyltransf_14 PF03421.16 CBY20945.1 - 0.0063 16.6 0.5 0.015 15.3 0.4 1.7 1 1 0 1 1 1 1 YopJ Serine/Threonine acetyltransferase DUF4201 PF13870.6 CBY20945.1 - 0.011 15.5 6.5 0.024 14.4 6.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.19 CBY20945.1 - 0.011 13.7 3.8 0.14 10.1 0.2 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 CBY20945.1 - 0.035 14.1 2.9 0.097 12.7 0.9 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus VirD1 PF07328.11 CBY20945.1 - 0.041 13.8 0.2 0.95 9.4 0.0 2.1 1 1 1 2 2 2 0 T-DNA border endonuclease VirD1 Lzipper-MIP1 PF14389.6 CBY20945.1 - 0.05 13.9 3.6 0.37 11.1 0.3 2.8 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Tmemb_cc2 PF10267.9 CBY20945.1 - 0.066 12.3 10.3 0.18 10.9 1.1 2.5 1 1 2 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein EKR PF10371.9 CBY20945.1 - 0.066 13.0 0.1 0.65 9.8 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function AATF-Che1 PF13339.6 CBY20945.1 - 0.068 13.8 3.4 0.17 12.6 3.4 1.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Nup54 PF13874.6 CBY20945.1 - 0.11 12.6 1.6 2.2 8.4 0.1 2.9 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Mt_ATP-synt_D PF05873.12 CBY20945.1 - 0.11 12.3 3.8 0.25 11.2 0.8 2.4 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Fib_alpha PF08702.10 CBY20945.1 - 0.15 12.2 7.5 0.071 13.3 3.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CBY20945.1 - 0.22 11.6 8.8 3.7 7.6 1.5 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 CBY20945.1 - 0.3 10.7 5.7 1.2 8.7 0.3 2.1 1 1 0 1 1 1 0 PspA/IM30 family TACC_C PF05010.14 CBY20945.1 - 0.3 10.8 9.7 0.29 10.9 5.1 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_II PF06009.12 CBY20945.1 - 0.3 11.1 9.5 1.4 9.0 0.7 2.9 2 1 1 3 3 3 0 Laminin Domain II Spectrin PF00435.21 CBY20945.1 - 0.31 11.5 5.3 0.48 10.9 0.4 2.5 1 1 1 2 2 2 0 Spectrin repeat DUF4795 PF16043.5 CBY20945.1 - 0.44 10.1 9.9 1.4 8.5 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) HAP1_N PF04849.13 CBY20945.1 - 0.44 9.7 11.6 5.3 6.2 11.6 2.2 1 1 0 1 1 1 0 HAP1 N-terminal conserved region NPV_P10 PF05531.12 CBY20945.1 - 0.44 11.0 7.7 5.2 7.6 0.5 3.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MIP-T3_C PF17749.1 CBY20945.1 - 0.57 10.1 9.4 0.28 11.2 3.5 2.6 1 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region CLZ PF16526.5 CBY20945.1 - 0.94 9.9 11.0 0.85 10.0 0.5 3.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 CBY20945.1 - 0.96 9.5 12.5 0.65 10.0 8.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 CBY20945.1 - 1.2 9.6 15.2 0.4 11.1 1.2 4.5 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 CBY20945.1 - 1.5 9.1 11.9 7 7.0 0.1 4.1 3 2 0 4 4 4 0 ABC transporter C-terminal domain DivIC PF04977.15 CBY20945.1 - 1.7 8.5 8.3 8.4 6.2 0.1 3.4 4 0 0 4 4 4 0 Septum formation initiator YabA PF06156.13 CBY20945.1 - 5.3 7.7 11.5 9.5 6.9 0.6 3.0 1 1 2 3 3 3 0 Initiation control protein YabA Kelch_6 PF13964.6 CBY20946.1 - 6.4e-06 26.3 0.0 0.02 15.2 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CBY20946.1 - 0.0019 18.2 0.3 0.8 9.8 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CBY20946.1 - 0.025 14.8 0.0 0.087 13.1 0.0 1.9 1 1 0 1 1 1 0 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY20946.1 - 0.081 12.9 0.1 5.9 7.0 0.0 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY20946.1 - 0.13 12.3 0.0 3.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Zona_pellucida PF00100.23 CBY20947.1 - 6e-20 72.1 2.2 6.9e-20 71.9 2.2 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain LolA PF03548.15 CBY20948.1 - 0.021 14.5 3.7 0.014 15.1 2.8 1.3 1 1 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Nrap_D5 PF17406.2 CBY20948.1 - 0.021 14.6 2.0 0.023 14.4 2.0 1.1 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 baeRF_family10 PF18854.1 CBY20948.1 - 0.11 12.7 0.2 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 GBP PF02263.19 CBY20949.1 - 3e-63 213.5 0.2 4.8e-63 212.9 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain 7tm_1 PF00001.21 CBY20949.1 - 0.0028 17.0 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3566 PF12089.8 CBY20949.1 - 0.057 13.8 0.7 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) TetR_C_23 PF17931.1 CBY20949.1 - 0.096 12.8 0.3 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FA_desaturase PF00487.24 CBY20949.1 - 0.18 11.6 0.1 0.4 10.5 0.0 1.5 2 0 0 2 2 2 0 Fatty acid desaturase RNA_pol_Rbc25 PF08292.12 CBY20950.1 - 4.7e-24 85.1 2.1 9.8e-22 77.6 2.1 2.2 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CBY20950.1 - 9.7e-16 57.9 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CBY20950.1 - 0.081 13.3 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain SpoIIE PF07228.12 CBY20951.1 - 2.9e-14 53.4 0.1 4.4e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CBY20951.1 - 4.9e-07 29.6 0.4 0.00084 19.0 0.1 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CBY20951.1 - 9.6e-05 22.1 0.0 0.00021 21.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Rad51 PF08423.11 CBY20952.1 - 4.4e-22 78.6 0.0 5.5e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CBY20952.1 - 2.9e-09 36.8 0.0 7.1e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CBY20952.1 - 1.2e-08 34.6 0.0 8.1e-08 31.9 0.0 2.2 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CBY20952.1 - 6e-08 32.3 0.0 8.3e-06 25.3 0.0 2.4 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain PhoH PF02562.16 CBY20952.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein RecA PF00154.21 CBY20952.1 - 0.0022 17.5 0.0 0.0044 16.5 0.0 1.5 1 1 0 1 1 1 1 recA bacterial DNA recombination protein DUF2075 PF09848.9 CBY20952.1 - 0.0097 15.2 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 CBY20952.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CBY20952.1 - 0.067 13.6 0.0 0.094 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CBY20952.1 - 0.071 13.5 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY20952.1 - 0.11 12.8 0.3 2 8.7 0.3 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBY20952.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Peptidase_S9 PF00326.21 CBY20953.1 - 1.3e-48 165.3 0.0 2.1e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 CBY20953.1 - 3.8e-45 154.2 0.3 5.5e-45 153.7 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 CBY20953.1 - 7.3e-09 35.6 0.1 4.7e-08 32.9 0.1 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 CBY20953.1 - 5.1e-07 29.6 0.0 3.5e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 CBY20953.1 - 0.0059 15.3 0.6 0.06 12.0 0.6 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 CBY20953.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY20953.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 CBY20953.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.16 CBY20953.1 - 0.05 13.4 0.2 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.12 CBY20953.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 GHL10 PF02638.15 CBY20954.1 - 0.018 14.1 0.0 0.02 14.0 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase-like 10 RNase_H2_suC PF08615.11 CBY20954.1 - 0.045 13.9 0.0 0.94 9.6 0.0 2.3 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Cys_Met_Meta_PP PF01053.20 CBY20955.1 - 3.3e-144 480.2 0.0 3.7e-144 480.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CBY20955.1 - 4.3e-06 25.5 0.0 6.4e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 CBY20955.1 - 4.7e-06 25.8 0.3 6.7e-06 25.3 0.3 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBY20955.1 - 0.0079 15.5 0.0 0.028 13.7 0.0 1.7 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Zona_pellucida PF00100.23 CBY20957.1 - 2.3e-05 24.3 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Arc_PepC_II PF06847.11 CBY20957.1 - 0.037 14.5 0.8 0.66 10.5 0.8 2.3 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II MazG-like PF12643.7 CBY20957.1 - 0.1 12.9 0.2 0.2 11.9 0.2 1.4 1 0 0 1 1 1 0 MazG-like family Zip PF02535.22 CBY20959.1 - 1e-49 169.6 11.6 1.2e-49 169.4 11.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1129 PF06570.11 CBY20959.1 - 2 7.8 5.1 13 5.2 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) DUF3512 PF12024.8 CBY20960.1 - 4e-12 46.1 0.2 2.6e-11 43.5 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3512) FIVAR PF07554.13 CBY20960.1 - 0.11 13.3 0.1 0.3 11.9 0.1 1.8 1 0 0 1 1 1 0 FIVAR domain Pkinase PF00069.25 CBY20961.1 - 7.2e-61 205.9 0.1 9.8e-61 205.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20961.1 - 9e-22 77.6 0.1 1.3e-21 77.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY20961.1 - 5.1e-08 32.6 0.0 8.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY20961.1 - 0.00032 20.1 1.4 0.00053 19.4 1.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY20961.1 - 0.038 13.6 0.2 0.08 12.5 0.2 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 CBY20961.1 - 0.082 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LSDAT_euk PF18139.1 CBY20963.1 - 2e-60 204.5 0.1 3.4e-60 203.7 0.1 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CBY20963.1 - 7.7e-13 48.1 0.4 1.4e-12 47.3 0.4 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 CBY20963.1 - 8.3e-12 44.9 16.8 8.3e-12 44.9 16.8 1.7 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 CBY20963.1 - 0.00095 17.9 0.5 0.00095 17.9 0.5 1.7 2 0 0 2 2 2 1 Polycystin cation channel PQQ_2 PF13360.6 CBY20964.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain SICA_beta PF12878.7 CBY20964.1 - 3.7 7.7 10.8 6.8 6.8 10.8 1.4 1 1 0 1 1 1 0 SICA extracellular beta domain GPW_gp25 PF04965.14 CBY20965.1 - 0.031 14.0 0.1 0.14 12.0 0.0 2.0 3 0 0 3 3 3 0 Gene 25-like lysozyme Siva PF05458.12 CBY20965.1 - 0.076 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) CCDC71L PF15374.6 CBY20965.1 - 0.55 9.4 6.3 1.4 8.1 6.5 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L DUF2149 PF09919.9 CBY20965.1 - 3.1 8.1 4.5 3.6 7.9 2.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2149) DASH_Dam1 PF08653.10 CBY20966.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 TFIIA PF03153.13 CBY20966.1 - 6 6.8 11.8 6.5 6.6 11.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pou PF00157.17 CBY20967.1 - 6.4e-37 125.4 0.1 1.2e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY20967.1 - 2.9e-16 59.1 1.8 2.9e-16 59.1 1.8 2.0 2 0 0 2 2 2 1 Homeodomain Pyr_redox_2 PF07992.14 CBY20968.1 - 5.9e-07 29.0 0.1 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF4821 PF16092.5 CBY20968.1 - 4.5e-05 23.2 0.1 7.9e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) NAC PF01849.18 CBY20968.1 - 0.06 13.3 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 NAC domain DUF4821 PF16092.5 CBY20970.1 - 2.5e-20 73.2 0.8 1.7e-19 70.5 0.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4821) DUF2963 PF11178.8 CBY20971.1 - 0.015 15.0 0.9 0.056 13.2 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) SGL PF08450.12 CBY20971.1 - 0.09 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Glyco_transf_8 PF01501.20 CBY20976.1 - 0.0028 17.3 1.0 1.1 8.7 0.1 2.4 1 1 1 2 2 2 2 Glycosyl transferase family 8 DUF5009 PF16401.5 CBY20977.1 - 0.38 10.2 7.9 0.02 14.4 1.6 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5009) SBDS PF01172.18 CBY20978.1 - 3.6e-31 107.1 1.9 4.1e-31 106.9 0.6 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CBY20978.1 - 4.7e-22 78.2 6.1 7.8e-22 77.5 6.1 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain DUF5314 PF17241.2 CBY20978.1 - 0.02 14.6 2.9 0.034 13.8 1.5 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5314) MTH865 PF07747.11 CBY20978.1 - 0.077 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 MTH865-like family KELK PF15796.5 CBY20978.1 - 0.25 11.8 2.4 0.54 10.8 0.2 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2981 PF11200.8 CBY20979.1 - 0.26 11.0 1.3 0.4 10.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) CybS PF05328.12 CBY20980.1 - 3e-11 43.1 0.1 3.2e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DUF2635 PF10948.8 CBY20980.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Evr1_Alr PF04777.13 CBY20981.1 - 2.5e-25 88.8 1.0 4.4e-25 88.1 1.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family NOA36 PF06524.12 CBY20982.1 - 6.4e-119 396.8 40.3 7.4e-119 396.6 40.3 1.0 1 0 0 1 1 1 1 NOA36 protein DUF1610 PF07754.11 CBY20982.1 - 0.012 15.5 0.7 0.012 15.5 0.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) Synaptobrevin PF00957.21 CBY20983.1 - 4.9e-15 55.1 1.0 9.7e-15 54.1 0.6 1.6 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 CBY20983.1 - 1.2e-10 41.3 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nsp1_C PF05064.13 CBY20983.1 - 0.0072 16.1 2.7 0.014 15.2 0.5 2.4 2 1 0 2 2 2 1 Nsp1-like C-terminal region EzrA PF06160.12 CBY20983.1 - 0.014 13.6 0.6 0.018 13.2 0.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TBCA PF02970.16 CBY20983.1 - 0.036 14.4 0.7 0.067 13.5 0.7 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A Sec8_exocyst PF04048.14 CBY20983.1 - 0.062 13.2 1.5 0.2 11.6 1.1 1.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain WD40_like PF17005.5 CBY20984.1 - 0.00021 20.7 0.1 0.00051 19.5 0.1 1.7 1 1 0 1 1 1 1 WD40-like domain PALB2_WD40 PF16756.5 CBY20984.1 - 0.021 13.8 0.1 1.6 7.6 0.0 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain MGC-24 PF05283.11 CBY20985.1 - 2.1e-11 44.4 0.2 2.5e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin NuA4 PF09340.10 CBY20987.1 - 3.9e-21 74.7 0.5 6e-21 74.1 0.5 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF2213 PF09979.9 CBY20987.1 - 0.1 12.6 1.2 0.39 10.7 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2213) TMEM252 PF15664.5 CBY20988.1 - 0.069 12.9 0.7 0.097 12.4 0.7 1.3 1 1 0 1 1 1 0 Transmembrane protein 252 family SPRY PF00622.28 CBY20989.1 - 1.8e-13 50.7 0.1 2.5e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 SPRY domain Pkinase_Tyr PF07714.17 CBY20990.1 - 3.9e-86 288.5 0.0 5.1e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY20990.1 - 1.8e-39 135.7 0.0 2.6e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CBY20990.1 - 1.2e-21 76.5 0.0 2.8e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CBY20990.1 - 4.8e-17 61.3 0.1 9.3e-17 60.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY20990.1 - 8.1e-14 51.2 0.0 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY20990.1 - 3.3e-10 39.5 0.2 7.9e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_10 PF17902.1 CBY20990.1 - 0.01 15.9 0.0 0.033 14.3 0.0 1.8 2 0 0 2 2 2 0 SH3 domain Haspin_kinase PF12330.8 CBY20990.1 - 0.062 12.2 0.0 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain SH3_3 PF08239.11 CBY20990.1 - 0.064 13.6 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF1751 PF08551.10 CBY20991.1 - 2.6e-21 76.0 3.1 2.6e-21 76.0 3.1 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Ubiquitin_2 PF14560.6 CBY20993.1 - 3.3e-26 91.6 0.0 7.2e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 CBY20993.1 - 1.4e-23 82.7 0.6 2.6e-23 81.8 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain CFAP91 PF14738.6 CBY20994.1 - 7.4e-52 175.5 15.2 7.4e-52 175.5 15.2 3.3 2 1 2 4 4 4 1 Cilia- and flagella-associated protein 91 IQ PF00612.27 CBY20994.1 - 0.18 11.7 1.2 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Cas_Cas6 PF01881.16 CBY20994.1 - 0.23 12.0 2.0 0.61 10.6 2.0 1.8 1 0 0 1 1 1 0 CRISPR associated protein Cas6 DUF2935 PF11155.8 CBY20994.1 - 6.8 7.1 8.4 2.4 8.5 3.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Pkinase PF00069.25 CBY20995.1 - 2.5e-67 227.0 0.0 2.9e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY20995.1 - 2.3e-51 174.6 0.0 2.8e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY20995.1 - 8.2e-08 31.4 0.0 9.9e-08 31.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY20995.1 - 0.00012 21.1 0.9 0.002 17.2 0.9 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY20995.1 - 0.008 15.5 0.1 0.38 10.0 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CBY20995.1 - 0.054 13.4 0.0 1.3 8.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abi_2 PF07751.11 CBY20995.1 - 0.12 12.6 0.2 0.37 11.1 0.0 1.8 2 1 0 2 2 2 0 Abi-like protein TFIIS_M PF07500.14 CBY20996.1 - 7.9e-36 123.0 2.3 7.9e-36 123.0 2.3 2.1 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CBY20996.1 - 3.1e-18 65.3 7.2 5e-18 64.7 7.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CBY20996.1 - 2e-11 43.7 2.3 2.4e-11 43.5 0.6 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain AreA_N PF07573.11 CBY20996.1 - 0.014 16.0 0.7 0.043 14.5 0.4 2.0 2 1 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus Ribosomal_60s PF00428.19 CBY20996.1 - 1.5 9.4 8.2 3.1 8.4 6.5 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein DUF1798 PF08807.10 CBY20996.1 - 4.3 7.5 10.3 0.92 9.7 1.0 3.2 4 0 0 4 4 4 0 Bacterial domain of unknown function (DUF1798) DUF775 PF05603.12 CBY20996.1 - 5.1 6.6 7.4 0.75 9.3 1.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF775) motB PF17613.2 CBY20997.1 - 0.0088 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Modifier of transcription FoP_duplication PF13865.6 CBY20997.1 - 6 7.5 18.7 9 6.9 18.7 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Glyco_hydro_20 PF00728.22 CBY20998.1 - 2.2e-79 267.4 0.1 3.1e-79 266.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CBY20998.1 - 3.2e-15 57.0 0.0 6.2e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CBY20998.1 - 2.6e-07 31.5 0.0 4.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Sulfotransfer_1 PF00685.27 CBY20999.1 - 1.3e-15 57.7 0.0 1.5e-14 54.1 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY20999.1 - 1.7e-11 45.0 0.0 5.8e-08 33.4 0.0 2.6 3 0 0 3 3 3 2 Sulfotransferase family Collagen PF01391.18 CBY21001.1 - 8.8e-19 67.0 65.6 1e-09 38.0 28.7 2.8 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY21001.1 - 2e-14 54.2 0.3 3.1e-14 53.6 0.3 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY21001.1 - 1.4e-10 41.8 0.0 7.2e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain RHD3 PF05879.12 CBY21001.1 - 0.0064 14.7 0.6 0.0086 14.3 0.6 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Tetraspanin PF00335.20 CBY21002.1 - 4.5e-06 26.5 0.7 4.5e-06 26.5 0.7 1.9 2 0 0 2 2 2 1 Tetraspanin family Mucin PF01456.17 CBY21002.1 - 0.0074 16.3 0.3 0.0074 16.3 0.3 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein SUR7 PF06687.12 CBY21002.1 - 0.15 11.7 12.4 2.4 7.7 8.1 2.5 2 0 0 2 2 2 0 SUR7/PalI family DUF3139 PF11337.8 CBY21002.1 - 0.31 11.7 2.4 2.7 8.7 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) PGF-CTERM PF18204.1 CBY21002.1 - 2.2 8.4 10.5 0.14 12.2 2.8 2.5 2 0 0 2 2 2 0 PGF-CTERM motif CUB PF00431.20 CBY21003.1 - 3.5e-11 43.4 0.1 7.4e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 CUB domain BshC PF10079.9 CBY21003.1 - 0.12 11.0 2.3 0.21 10.3 2.3 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC VWA_3 PF13768.6 CBY21004.1 - 8.5e-15 55.0 0.2 3.1e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY21004.1 - 1e-13 51.9 0.3 4.9e-13 49.7 0.2 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CBY21004.1 - 2.6e-11 44.1 1.0 8.3e-11 42.4 1.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 CBY21004.1 - 0.00033 20.8 0.5 0.0019 18.4 0.1 2.4 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain DUF4718 PF15842.5 CBY21005.1 - 0.027 14.3 0.4 0.058 13.2 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) CSD PF00313.22 CBY21006.1 - 3.2e-30 103.8 12.9 1.6e-08 34.3 0.4 6.5 7 0 0 7 7 7 4 'Cold-shock' DNA-binding domain S1-like PF14444.6 CBY21006.1 - 5.2e-08 32.7 2.7 0.2 11.6 0.1 3.9 3 1 0 3 3 3 3 S1-like S1 PF00575.23 CBY21006.1 - 1.5e-05 25.3 2.4 0.0032 17.8 0.1 4.0 3 0 0 3 3 3 1 S1 RNA binding domain Rho_RNA_bind PF07497.12 CBY21006.1 - 0.00066 19.5 0.0 0.78 9.6 0.0 3.3 3 0 0 3 3 3 2 Rho termination factor, RNA-binding domain CusF_Ec PF11604.8 CBY21006.1 - 0.0054 16.7 0.8 9.5 6.3 0.0 4.1 4 0 0 4 4 4 1 Copper binding periplasmic protein CusF OB_RNB PF08206.11 CBY21006.1 - 0.018 14.7 8.5 1.3 8.7 0.1 3.9 4 0 0 4 4 4 0 Ribonuclease B OB domain Nsp1 PF11501.8 CBY21006.1 - 0.17 12.0 0.1 43 4.2 0.0 3.2 3 0 0 3 3 3 0 Non structural protein Nsp1 LRR_8 PF13855.6 CBY21009.1 - 3.9e-05 23.3 0.5 0.00029 20.5 0.1 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CBY21009.1 - 0.0029 18.0 8.5 0.043 14.2 2.2 3.5 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY21009.1 - 0.04 14.4 7.0 8.5 7.4 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat WD40_like PF17005.5 CBY21009.1 - 0.18 11.1 0.0 1.8 7.8 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 CBY21009.1 - 0.21 12.5 1.0 27 5.9 0.0 3.7 5 0 0 5 5 5 0 WD domain, G-beta repeat RhoGAP PF00620.27 CBY21010.1 - 5.1e-13 49.1 0.1 6.2e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain Septin PF00735.18 CBY21012.1 - 6.3e-125 416.1 0.1 6.3e-125 416.1 0.1 2.4 3 0 0 3 3 3 1 Septin MMR_HSR1 PF01926.23 CBY21012.1 - 5.2e-08 33.0 0.0 1.7e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY21012.1 - 3.5e-07 30.3 3.2 4.5e-06 26.7 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CBY21012.1 - 3.6e-06 26.7 1.7 0.0081 15.7 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CBY21012.1 - 0.00022 20.6 0.1 0.0007 19.0 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 CBY21012.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY21012.1 - 0.0058 16.3 0.0 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.27 CBY21012.1 - 0.015 15.8 1.0 0.028 15.0 0.2 2.0 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 CBY21012.1 - 0.019 15.2 0.0 0.083 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBY21012.1 - 0.03 13.8 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CBY21012.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 CBY21012.1 - 0.36 10.9 7.7 2.9 7.9 0.0 3.4 3 1 1 4 4 4 0 Dynamin family AAA_23 PF13476.6 CBY21012.1 - 0.52 10.8 6.5 0.1 13.1 0.4 2.7 2 1 0 2 2 2 0 AAA domain TFIID_30kDa PF03540.13 CBY21013.1 - 6.2e-18 64.5 0.1 1.2e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit DSBA PF01323.20 CBY21013.1 - 0.048 13.4 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain adh_short_C2 PF13561.6 CBY21014.1 - 2.1e-54 184.6 0.2 2.6e-54 184.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY21014.1 - 3.9e-47 160.2 0.2 4.7e-47 160.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY21014.1 - 6e-10 39.3 0.1 8.4e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 CBY21014.1 - 0.031 14.9 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 CBY21014.1 - 0.083 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Rhodanese PF00581.20 CBY21015.1 - 7.5e-13 48.9 0.0 9.2e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Atg14 PF10186.9 CBY21016.1 - 0.00017 20.8 4.0 8.2 5.4 15.2 2.2 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 CBY21016.1 - 0.095 12.9 16.5 0.53 10.6 5.2 3.0 2 1 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 CBY21016.1 - 1.8 9.1 17.2 0.4 11.2 2.9 2.8 2 1 0 2 2 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 CBY21016.1 - 2.6 7.6 5.1 3.7 7.0 5.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit F-box-like PF12937.7 CBY21017.1 - 7.7e-09 35.3 4.3 2e-08 34.0 4.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY21017.1 - 3.3e-08 33.2 3.7 7.4e-08 32.1 3.7 1.6 1 0 0 1 1 1 1 F-box domain RNA_pol_Rpb1_5 PF04998.17 CBY21018.1 - 5.5e-92 308.0 0.7 6.8e-92 307.7 0.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_7 PF04990.12 CBY21018.1 - 1.8e-54 183.4 5.4 3.3e-54 182.5 5.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_R PF05001.13 CBY21018.1 - 3.6e-22 77.5 450.1 0.03 14.7 14.1 24.0 3 1 30 35 35 35 31 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_6 PF04992.14 CBY21018.1 - 1e-20 74.4 0.8 8.2e-19 68.2 0.1 2.3 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 6 VasI PF11319.8 CBY21018.1 - 0.088 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 RNA_pol_Rpb1_3 PF04983.18 CBY21019.1 - 1.9e-23 83.1 0.0 2.2e-23 82.9 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.20 CBY21019.1 - 0.011 16.0 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CBY21020.1 - 5.6e-88 295.3 0.0 5.6e-50 170.5 0.0 2.1 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CBY21020.1 - 7.7e-05 23.0 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 MCM PF00493.23 CBY21021.1 - 1.8e-99 331.4 0.0 4e-99 330.3 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CBY21021.1 - 2e-33 114.9 1.0 2e-33 114.9 1.0 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 CBY21021.1 - 5e-20 71.7 2.3 1.4e-19 70.3 2.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBY21021.1 - 1.5e-17 64.0 0.3 3.5e-17 62.9 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY21021.1 - 3e-08 33.3 1.1 1.3e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY21021.1 - 8.2e-07 29.1 0.0 3.3e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_bind PF09739.9 CBY21021.1 - 4.6e-05 22.1 1.2 8.1e-05 21.3 1.2 1.3 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor AAA_3 PF07726.11 CBY21021.1 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 CBY21021.1 - 0.0016 19.1 0.1 0.0072 16.9 0.1 2.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal PIG-S PF10510.9 CBY21021.1 - 0.024 13.5 0.2 0.037 12.9 0.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Sigma54_activat PF00158.26 CBY21021.1 - 0.035 13.8 0.1 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain zf_UBZ PF18439.1 CBY21021.1 - 0.11 12.1 1.2 0.52 10.0 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger AAA_lid_2 PF17863.1 CBY21021.1 - 0.16 11.8 1.2 1.3 8.9 0.1 2.9 3 0 0 3 3 3 0 AAA lid domain LRR_9 PF14580.6 CBY21022.1 - 1.2e-13 51.0 2.6 1.8e-13 50.3 2.6 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBY21022.1 - 4e-10 39.8 10.2 1.5e-05 25.3 1.0 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY21022.1 - 1.5e-08 34.2 1.3 1.5e-08 34.2 1.3 3.1 3 1 0 3 3 3 1 Leucine rich repeat LRR_2 PF07723.13 CBY21022.1 - 0.45 11.3 1.3 31 5.5 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CBY21022.1 - 1.3 9.2 7.7 49 4.3 0.4 3.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CBY21022.1 - 1.8 9.5 10.1 1.2e+02 3.8 0.1 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat BHD_3 PF10405.9 CBY21023.1 - 8.3e-22 77.4 0.0 1.7e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CBY21023.1 - 2.3e-14 53.0 0.7 6.6e-14 51.5 0.1 2.2 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CBY21023.1 - 1.6e-10 41.8 0.2 1.6e-10 41.8 0.2 6.5 3 2 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CBY21023.1 - 0.024 15.1 0.0 0.85 10.1 0.0 2.8 2 0 0 2 2 2 0 Transglutaminase-like superfamily Serpin PF00079.20 CBY21024.1 - 1.2e-32 113.7 0.0 1.3e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) GTP_EFTU_D3 PF03143.17 CBY21024.1 - 0.074 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain zf-RING_2 PF13639.6 CBY21025.1 - 5.3e-12 45.9 5.4 9.2e-12 45.1 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBY21025.1 - 3.6e-10 39.4 3.9 3.6e-10 39.4 3.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBY21025.1 - 2.3e-08 33.7 4.9 3.5e-08 33.1 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY21025.1 - 1.4e-07 31.4 2.9 3.1e-07 30.3 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY21025.1 - 1.5e-07 31.1 3.8 2.7e-07 30.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY21025.1 - 5.1e-07 29.5 3.0 8.4e-07 28.9 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY21025.1 - 3.6e-06 26.7 1.0 5.6e-06 26.1 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY21025.1 - 5.5e-06 26.6 8.6 1.2e-05 25.4 7.0 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CBY21025.1 - 0.016 15.1 2.0 0.037 13.9 2.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 CBY21025.1 - 0.026 14.6 5.4 0.054 13.5 5.4 1.6 1 1 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 CBY21025.1 - 0.034 13.8 2.2 0.071 12.7 2.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type REV PF00424.18 CBY21025.1 - 0.12 12.5 2.5 0.18 11.8 2.5 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) FANCL_C PF11793.8 CBY21025.1 - 0.15 12.3 7.1 2.8 8.2 7.1 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CBY21025.1 - 0.38 10.8 6.6 8.4 6.5 6.7 2.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CBY21025.1 - 2.3 8.4 6.5 12 6.1 5.3 2.3 1 1 1 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 CBY21025.1 - 2.3 8.4 6.1 5.1 7.4 6.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Adeno_E3_CR2 PF02439.15 CBY21026.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kelch_1 PF01344.25 CBY21028.1 - 3.1e-23 81.1 0.0 4e-09 35.9 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CBY21028.1 - 5.6e-22 77.2 0.4 1.5e-07 31.4 0.0 5.6 2 1 3 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CBY21028.1 - 9.7e-19 67.1 0.0 5.1e-06 26.4 0.0 5.2 5 1 0 5 5 5 3 Galactose oxidase, central domain BTB PF00651.31 CBY21028.1 - 1.8e-15 57.1 0.1 1.9e-14 53.8 0.1 2.4 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 CBY21028.1 - 3.2e-11 43.2 0.0 0.0023 18.2 0.0 4.9 4 1 0 4 4 4 3 Galactose oxidase, central domain BACK PF07707.15 CBY21028.1 - 8.2e-09 35.5 0.2 1.7e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CBY21028.1 - 3.2e-08 33.2 0.4 0.053 13.5 0.0 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY21028.1 - 2e-07 30.8 0.0 0.027 14.5 0.0 5.1 5 1 0 5 5 5 1 Kelch motif Trypsin PF00089.26 CBY21029.1 - 3.3e-25 89.2 0.7 4e-25 88.9 0.7 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_C3 PF00548.20 CBY21029.1 - 0.058 13.3 2.0 0.65 9.9 0.3 2.3 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) DUF1986 PF09342.11 CBY21029.1 - 0.15 12.4 0.1 0.29 11.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) DUF92 PF01940.16 CBY21030.1 - 0.024 14.0 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 Zona_pellucida PF00100.23 CBY21031.1 - 3.4e-38 131.9 5.9 5.1e-38 131.4 5.9 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.27 CBY21031.1 - 4.3e-05 23.7 7.2 4.3e-05 23.7 7.2 2.5 2 0 0 2 2 2 1 EGF-like domain DUF1616 PF07760.11 CBY21031.1 - 0.0018 17.7 0.7 0.26 10.6 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1616) TMEM154 PF15102.6 CBY21031.1 - 0.016 15.1 0.3 0.031 14.2 0.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 CBY21031.1 - 0.025 14.4 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 CBY21031.1 - 0.033 15.1 0.5 0.078 13.9 0.5 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EGF_2 PF07974.13 CBY21031.1 - 1.6 9.1 16.6 0.75 10.2 8.4 3.0 2 0 0 2 2 2 0 EGF-like domain ANF_receptor PF01094.28 CBY21032.1 - 3.1e-06 26.5 0.2 4.1e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 CBY21033.1 - 4.9e-24 85.1 0.3 6.3e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Arf PF00025.21 CBY21034.1 - 2.2e-57 193.3 0.0 2.7e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY21034.1 - 1.8e-12 47.5 0.0 2.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBY21034.1 - 3.9e-11 42.7 0.0 5e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBY21034.1 - 7.8e-11 41.8 0.0 9.1e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY21034.1 - 3.8e-08 32.9 0.1 9.9e-06 24.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY21034.1 - 9.7e-08 31.6 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY21034.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBY21034.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MeaB PF03308.16 CBY21034.1 - 0.024 13.6 0.0 4 6.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Med29 PF11568.8 CBY21034.1 - 0.17 12.1 0.1 0.28 11.4 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 FOXP-CC PF16159.5 CBY21035.1 - 1.6e-30 105.5 5.1 2.6e-30 104.8 5.1 1.3 1 0 0 1 1 1 1 FOXP coiled-coil domain Forkhead PF00250.18 CBY21035.1 - 6.8e-27 93.5 0.2 1.3e-26 92.6 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain HTH_31 PF13560.6 CBY21035.1 - 0.0034 17.7 0.0 0.0057 17.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Zap1_zf2 PF18217.1 CBY21035.1 - 0.16 12.0 1.1 0.32 11.0 1.1 1.5 1 0 0 1 1 1 0 Zap1 zinc finger 2 Pro_3_hydrox_C PF05373.11 CBY21036.1 - 0.043 13.9 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Zn_Tnp_IS1595 PF12760.7 CBY21036.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Foie-gras_1 PF11817.8 CBY21036.1 - 0.097 12.2 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 EGF PF00008.27 CBY21037.1 - 1.4e-08 34.8 14.0 0.00033 20.9 0.9 2.3 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 CBY21037.1 - 1.6e-05 25.4 11.1 0.00071 20.1 2.0 2.8 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.13 CBY21037.1 - 0.00035 20.9 1.6 0.00035 20.9 1.6 2.4 2 0 0 2 2 2 1 EGF-like domain Orthopox_A5L PF06193.11 CBY21037.1 - 0.031 13.7 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like AMP-binding PF00501.28 CBY21042.1 - 7.7e-65 219.1 0.0 9.5e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY21042.1 - 0.0065 17.4 0.0 0.014 16.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIP49_C PF12260.8 CBY21043.1 - 0.03 14.0 0.4 0.055 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Peptidase_M19 PF01244.21 CBY21044.1 - 3.8e-90 302.3 0.0 5.4e-90 301.8 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Zip PF02535.22 CBY21044.1 - 7.5e-28 97.7 6.2 1.3e-20 73.9 0.0 2.2 1 1 0 2 2 2 2 ZIP Zinc transporter PMP22_Claudin PF00822.20 CBY21045.1 - 0.0055 16.6 6.8 0.088 12.7 0.4 3.0 3 0 0 3 3 3 1 PMP-22/EMP/MP20/Claudin family Saf_2TM PF18303.1 CBY21045.1 - 0.0081 15.8 2.8 1.1 8.9 1.2 2.2 2 0 0 2 2 2 2 SAVED-fused 2TM effector domain Frag1 PF10277.9 CBY21045.1 - 0.0091 15.6 12.9 0.017 14.6 11.6 1.8 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family DUF2157 PF09925.9 CBY21045.1 - 0.011 15.5 4.1 4.3 7.1 0.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Cortexin PF11057.8 CBY21045.1 - 0.018 14.9 5.6 3.1 7.7 0.1 3.5 4 0 0 4 4 4 0 Cortexin of kidney SdpI PF13630.6 CBY21045.1 - 0.094 12.9 3.6 1.3 9.3 0.8 2.8 3 0 0 3 3 3 0 SdpI/YhfL protein family SpoIIM PF01944.17 CBY21045.1 - 0.12 12.4 8.4 0.52 10.3 8.4 1.9 1 1 0 1 1 1 0 Stage II sporulation protein M Pox_A14 PF05767.12 CBY21045.1 - 0.25 11.5 0.2 0.25 11.5 0.2 3.5 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 DUF3899 PF13038.6 CBY21045.1 - 0.36 11.4 5.8 1.5 9.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) DUF4013 PF13197.6 CBY21045.1 - 0.85 9.4 9.7 0.29 10.9 4.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) DUF2304 PF10066.9 CBY21045.1 - 0.89 9.8 7.8 1.1 9.5 2.2 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Na_Ala_symp PF01235.17 CBY21045.1 - 0.93 8.7 8.3 0.2 10.9 4.1 1.9 2 1 0 2 2 2 0 Sodium:alanine symporter family DUF4612 PF15389.6 CBY21048.1 - 0.2 12.7 3.0 0.29 12.2 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) PHO4 PF01384.20 CBY21049.1 - 1.7e-118 395.6 9.3 2.5e-118 395.0 9.3 1.3 1 0 0 1 1 1 1 Phosphate transporter family Stathmin PF00836.19 CBY21049.1 - 0.019 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Stathmin family HHH_3 PF12836.7 CBY21050.1 - 1.5e-13 50.8 0.0 2.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif PsbU PF06514.11 CBY21050.1 - 0.00066 19.6 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH PF00633.23 CBY21050.1 - 0.0058 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_6 PF14579.6 CBY21050.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Kelch_4 PF13418.6 CBY21051.1 - 1.4e-28 98.6 12.7 6.9e-07 29.2 0.3 7.1 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY21051.1 - 9.6e-27 92.7 6.1 3.7e-07 30.3 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY21051.1 - 8.2e-19 66.9 1.8 0.0046 16.5 0.0 7.2 7 1 0 7 7 7 5 Kelch motif Kelch_5 PF13854.6 CBY21051.1 - 1.5e-18 66.3 0.4 0.046 13.7 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBY21051.1 - 6.2e-16 58.0 12.3 0.00024 21.3 0.0 6.6 5 1 2 7 7 7 4 Kelch motif Kelch_2 PF07646.15 CBY21051.1 - 2.7e-08 33.5 4.1 1 9.4 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Na_H_Exchanger PF00999.21 CBY21052.1 - 4.1e-71 239.8 33.4 1.4e-70 238.0 33.4 1.7 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family PDR_CDR PF06422.12 CBY21052.1 - 8.9 6.3 11.4 11 6.0 0.3 3.6 3 0 0 3 3 3 0 CDR ABC transporter Mito_carr PF00153.27 CBY21053.1 - 1.9e-33 114.2 2.6 9.9e-12 44.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EMP24_GP25L PF01105.24 CBY21054.1 - 3.5e-49 167.2 1.1 4e-49 167.0 1.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MCR_C PF04609.12 CBY21054.1 - 0.029 13.5 0.1 0.036 13.1 0.1 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C SdrD_B PF17210.3 CBY21054.1 - 0.041 14.1 0.0 0.071 13.3 0.0 1.5 1 1 0 1 1 1 0 SdrD B-like domain Innexin PF00876.18 CBY21054.1 - 0.06 12.6 0.2 0.074 12.3 0.2 1.1 1 0 0 1 1 1 0 Innexin WD40 PF00400.32 CBY21055.1 - 1.4e-14 54.3 13.0 8.6e-05 23.2 0.1 6.3 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21055.1 - 1.1e-09 38.5 0.2 0.0026 18.0 0.0 4.6 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain CLTH PF10607.9 CBY21055.1 - 6.9e-06 26.0 0.6 1.2e-05 25.2 0.6 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH_TPL PF17814.1 CBY21055.1 - 0.003 17.2 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain eIF2A PF08662.11 CBY21055.1 - 0.021 14.7 0.3 0.36 10.7 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Borrelia_lipo_1 PF05714.11 CBY21055.1 - 0.082 12.7 0.2 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein PDZ PF00595.24 CBY21056.1 - 0.0019 18.5 1.2 0.0019 18.5 1.2 2.1 2 1 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CBY21056.1 - 0.0027 17.5 0.1 0.0055 16.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Fasciclin PF02469.22 CBY21056.1 - 0.088 13.0 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 Fasciclin domain Spore_GerAC PF05504.11 CBY21056.1 - 0.16 12.2 0.0 0.33 11.1 0.0 1.5 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal UQ_con PF00179.26 CBY21057.1 - 1.6e-41 141.2 0.3 1.8e-41 141.1 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY21057.1 - 0.00038 20.7 0.3 0.00052 20.3 0.3 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CBY21057.1 - 0.001 18.8 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBY21057.1 - 0.0087 15.9 0.2 0.015 15.1 0.2 1.4 1 1 0 1 1 1 1 UEV domain UFC1 PF08694.11 CBY21057.1 - 0.017 14.7 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 IFT43 PF15305.6 CBY21059.1 - 0.052 13.7 0.0 0.058 13.6 0.0 1.1 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Peptidase_M17 PF00883.21 CBY21060.1 - 7.8e-110 367.0 0.3 1.1e-109 366.4 0.0 1.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CBY21060.1 - 2.1e-08 34.1 0.2 4.1e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain VKOR PF07884.14 CBY21061.1 - 8.2e-15 55.1 5.4 9.8e-15 54.8 5.4 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family DUF4401 PF14351.6 CBY21061.1 - 0.019 14.3 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) CPBP PF02517.16 CBY21061.1 - 0.089 13.2 0.9 0.15 12.4 0.9 1.4 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease Peptidase_M7 PF02031.16 CBY21062.1 - 0.032 14.4 0.1 0.08 13.1 0.1 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family wnt PF00110.19 CBY21063.1 - 5.5e-42 144.4 15.3 8.3e-31 107.7 9.2 2.1 1 1 1 2 2 2 2 wnt family OTU PF02338.19 CBY21064.1 - 2e-14 54.2 0.3 1.9e-13 51.0 0.0 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CBY21064.1 - 5.1e-06 26.1 0.2 0.09 12.2 0.1 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain DUF4355 PF14265.6 CBY21064.1 - 6.1 7.1 15.2 5.2 7.3 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) NTP_transf_2 PF01909.23 CBY21065.1 - 1.2e-05 25.5 0.0 2.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBY21065.1 - 0.0054 16.8 0.0 0.02 15.0 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase TFIIA PF03153.13 CBY21066.1 - 1.6e-57 196.4 3.3 1.8e-37 130.3 2.5 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Iso_dh PF00180.20 CBY21067.1 - 5.9e-70 236.1 0.0 7.2e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 CBY21067.1 - 0.0093 16.7 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 1 Phenylalanine zipper Pkinase PF00069.25 CBY21068.1 - 1.9e-66 224.1 0.2 5.1e-66 222.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21068.1 - 1.1e-29 103.6 0.0 1.7e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY21068.1 - 2.9e-07 30.1 0.0 4.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY21068.1 - 5.9e-05 22.5 0.8 7.7e-05 22.1 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPOUT_MTase_2 PF14419.6 CBY21068.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP APH PF01636.23 CBY21068.1 - 0.2 11.6 0.0 16 5.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family O-FucT PF10250.9 CBY21069.1 - 8.1e-08 32.3 0.3 9.8e-07 28.8 0.3 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CoA_binding_3 PF13727.6 CBY21069.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain YhhN PF07947.14 CBY21070.1 - 4.6e-33 114.4 10.0 5.9e-33 114.0 10.0 1.1 1 0 0 1 1 1 1 YhhN family HMG_box PF00505.19 CBY21071.1 - 2.2e-17 63.2 0.2 4.8e-17 62.1 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY21071.1 - 7.5e-12 45.7 0.2 1.7e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 CBY21071.1 - 0.073 13.6 3.8 0.079 13.5 2.4 1.9 1 1 0 1 1 1 0 YABBY protein HMG_box_5 PF14887.6 CBY21071.1 - 0.096 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Aa_trans PF01490.18 CBY21072.1 - 2e-26 92.7 30.4 4.8e-18 65.1 2.9 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBY21072.1 - 3.3e-06 26.4 4.1 3.3e-06 26.4 4.1 2.9 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family Kringle PF00051.18 CBY21073.1 - 3.1e-10 40.2 6.5 1e-09 38.6 6.5 1.7 1 1 0 1 1 1 1 Kringle domain Trypsin PF00089.26 CBY21074.1 - 2e-43 148.7 0.0 3e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 CBY21074.1 - 9.1e-22 77.2 19.5 1.2e-13 51.1 7.6 3.2 3 1 0 3 3 3 2 Kringle domain DUF1986 PF09342.11 CBY21074.1 - 0.01 16.2 0.1 2.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) NKWYS PF10364.9 CBY21074.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein T2SSB PF16537.5 CBY21075.1 - 0.059 13.0 0.4 0.14 11.8 0.4 1.6 1 0 0 1 1 1 0 Type II secretion system protein B SR-25 PF10500.9 CBY21075.1 - 0.1 12.2 33.2 0.25 10.9 12.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 CBY21075.1 - 0.76 8.3 41.9 1 7.9 41.9 1.1 1 0 0 1 1 1 0 Utp14 protein Piwi PF02171.17 CBY21076.1 - 1.3e-55 188.7 0.0 1.9e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CBY21076.1 - 2.2e-08 34.8 0.0 4.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CBY21076.1 - 3.1e-05 23.5 0.0 8.6e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CBY21076.1 - 0.0041 17.4 0.1 0.011 16.1 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain Phospholip_A2_1 PF00068.19 CBY21077.1 - 7.1e-11 42.6 9.6 7.1e-11 42.6 9.6 2.1 2 0 0 2 2 2 1 Phospholipase A2 zf-H2C2_2 PF13465.6 CBY21078.1 - 1.6e-18 66.2 24.1 1.5e-08 34.7 0.4 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY21078.1 - 1.5e-16 59.8 28.2 1.2e-05 25.5 1.6 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf_ZIC PF18366.1 CBY21078.1 - 5.9e-10 39.1 0.4 5.9e-10 39.1 0.4 4.0 5 0 0 5 5 5 1 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 CBY21078.1 - 5.3e-08 33.1 27.6 0.012 16.4 0.5 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY21078.1 - 0.0035 17.6 2.6 6.9 7.1 0.1 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CBY21078.1 - 0.0058 16.9 10.0 0.15 12.4 3.4 3.1 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-met PF12874.7 CBY21078.1 - 0.043 14.2 6.0 1.9 9.0 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CBY21078.1 - 0.2 11.5 1.7 0.37 10.6 0.2 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type CHORD PF04968.12 CBY21078.1 - 0.99 10.2 19.2 3.2 8.5 0.9 4.4 2 1 2 4 4 4 0 CHORD zf-C2H2_6 PF13912.6 CBY21078.1 - 1.7 8.7 10.4 1.5 8.9 0.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CBY21078.1 - 4.8 7.3 12.3 32 4.6 0.9 3.8 1 1 3 4 4 4 0 Aberrant zinc-finger HNH PF01844.23 CBY21078.1 - 5.2 7.3 6.9 1.1 9.5 0.4 3.0 3 0 0 3 3 3 0 HNH endonuclease 7tm_1 PF00001.21 CBY21079.1 - 0.12 11.7 1.2 0.15 11.3 1.2 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) zinc_ribbon_10 PF10058.9 CBY21080.1 - 3.7e-17 61.8 0.2 7.8e-17 60.7 0.2 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein MRI PF15325.6 CBY21080.1 - 0.4 11.8 9.1 1.4 10.1 9.1 1.9 1 0 0 1 1 1 0 Modulator of retrovirus infection Na_trans_assoc PF06512.13 CBY21080.1 - 1.4 9.2 10.9 0.33 11.2 7.5 1.6 2 0 0 2 2 2 0 Sodium ion transport-associated DUF2048 PF09752.9 CBY21081.1 - 8.4e-69 232.3 0.0 9.9e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Sigma70_r4_2 PF08281.12 CBY21081.1 - 0.0002 20.9 0.1 0.0021 17.7 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Lipase_3 PF01764.25 CBY21081.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 CBY21081.1 - 0.13 12.2 0.2 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ABC_tran_CTD PF16326.5 CBY21082.1 - 0.016 15.5 0.1 0.019 15.2 0.1 1.1 1 0 0 1 1 1 0 ABC transporter C-terminal domain MIF4G PF02854.19 CBY21083.1 - 4e-06 26.6 0.7 9.6e-06 25.4 0.7 1.7 1 1 0 1 1 1 1 MIF4G domain GHMP_kinases_C PF08544.13 CBY21084.1 - 3.7e-08 33.6 0.1 1e-07 32.2 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal Cnd1_N PF12922.7 CBY21084.1 - 0.052 13.4 0.2 0.068 13.0 0.2 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term GalKase_gal_bdg PF10509.9 CBY21085.1 - 0.0065 16.0 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DNA_pol_B PF00136.21 CBY21086.1 - 1.8e-144 481.9 0.1 2.5e-144 481.4 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBY21086.1 - 8.2e-84 281.6 0.4 1.2e-83 281.1 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CBY21086.1 - 6.5e-15 55.4 10.0 1.5e-14 54.2 10.0 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CBY21086.1 - 0.00034 19.6 0.2 0.0017 17.3 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DUF4309 PF14172.6 CBY21086.1 - 0.049 13.6 0.1 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4309) DZR PF12773.7 CBY21086.1 - 0.77 9.8 9.9 1.5 8.9 0.4 2.7 2 0 0 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.6 CBY21086.1 - 10 6.2 10.8 7.5 6.6 2.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 THF_DHG_CYH_C PF02882.19 CBY21087.1 - 5e-38 129.9 0.0 7.5e-38 129.4 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBY21087.1 - 6.8e-32 110.2 0.0 9.2e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Importin_rep_4 PF18808.1 CBY21088.1 - 3.6e-20 72.0 0.2 3.6e-20 72.0 0.2 3.6 5 0 0 5 5 3 1 Importin repeat HEAT_2 PF13646.6 CBY21088.1 - 2.8e-17 62.9 2.8 3.1e-05 24.3 0.1 7.9 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 CBY21088.1 - 2.9e-13 50.0 12.4 7.1e-11 42.4 0.2 7.0 8 0 0 8 8 8 1 HEAT-like repeat HEAT PF02985.22 CBY21088.1 - 2.8e-12 45.8 15.5 3.9e-05 23.5 0.0 8.8 10 0 0 10 10 7 2 HEAT repeat Cnd1 PF12717.7 CBY21088.1 - 2.8e-12 47.0 0.1 2e-06 27.9 0.1 4.4 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBY21088.1 - 7.9e-10 39.2 0.0 0.00045 20.8 0.0 4.5 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CBY21088.1 - 1.9e-09 37.5 0.0 0.028 14.0 0.0 4.4 3 1 1 4 4 4 3 CLASP N terminal Adaptin_N PF01602.20 CBY21088.1 - 6.6e-06 25.0 2.9 5.6e-05 21.9 0.3 3.2 3 1 0 4 4 4 1 Adaptin N terminal region RIX1 PF08167.12 CBY21088.1 - 3.3e-05 23.7 1.2 0.87 9.3 0.0 4.8 4 3 2 6 6 6 2 rRNA processing/ribosome biogenesis Importin_rep_6 PF18829.1 CBY21088.1 - 0.00014 22.0 0.2 0.00085 19.4 0.2 2.4 2 0 0 2 2 2 1 Importin repeat 6 MMS19_C PF12460.8 CBY21088.1 - 0.00024 20.4 4.8 0.047 12.8 0.2 3.8 2 1 2 4 4 4 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 CBY21088.1 - 0.00032 20.6 1.1 0.39 10.6 0.0 5.0 4 3 2 6 6 6 1 Domain of unknown function (DUF3385) UME PF08064.13 CBY21088.1 - 0.0016 18.3 0.4 0.81 9.6 0.0 3.9 4 1 0 4 4 3 1 UME (NUC010) domain IBN_N PF03810.19 CBY21088.1 - 0.0019 18.1 0.6 0.031 14.2 0.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain IFRD PF05004.13 CBY21088.1 - 0.0042 16.2 0.5 2.4 7.2 0.0 4.7 5 2 0 5 5 5 1 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 CBY21088.1 - 0.0048 16.5 0.2 0.65 9.5 0.0 3.9 3 1 1 4 4 4 1 Tti2 family Arm PF00514.23 CBY21088.1 - 0.081 13.0 0.2 8.5 6.6 0.0 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TPX2 PF06886.11 CBY21089.1 - 1.9e-06 28.0 10.5 1.9e-06 28.0 10.5 3.6 4 0 0 4 4 4 1 Targeting protein for Xklp2 (TPX2) bZIP_Maf PF03131.17 CBY21090.1 - 8.3e-19 67.9 3.3 1.1e-18 67.5 3.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 CBY21090.1 - 2.4e-05 24.3 10.0 3.7e-05 23.7 10.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor TPR_MLP1_2 PF07926.12 CBY21090.1 - 0.01 15.9 2.3 0.016 15.3 2.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 CBY21090.1 - 0.021 14.1 1.9 0.027 13.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TSC22 PF01166.18 CBY21090.1 - 0.22 11.9 2.6 3.1 8.2 0.7 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.15 CBY21090.1 - 0.47 10.6 9.0 0.86 9.7 9.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper MMR_HSR1_Xtn PF16897.5 CBY21091.1 - 1.7e-40 137.3 0.5 2.8e-40 136.6 0.5 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CBY21091.1 - 5.2e-23 80.9 0.1 9.2e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CBY21091.1 - 2.7e-18 66.1 0.0 5.2e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY21091.1 - 1.1e-09 38.1 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 CBY21091.1 - 0.06 13.9 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 CBY21091.1 - 0.08 11.9 0.2 0.21 10.5 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SafA PF17073.5 CBY21091.1 - 0.099 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Two-component-system connector protein DEAD PF00270.29 CBY21093.1 - 2.4e-51 174.0 0.0 4.6e-50 169.8 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY21093.1 - 1.9e-30 105.5 0.0 7.5e-29 100.3 0.1 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY21093.1 - 0.00011 22.2 0.0 0.00033 20.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY21093.1 - 0.00016 21.0 0.6 0.00023 20.5 0.1 1.4 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 CBY21093.1 - 0.063 12.1 0.0 0.18 10.5 0.0 1.7 1 1 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CBY21093.1 - 0.2 11.9 0.3 0.86 9.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain Glyco_transf_49 PF13896.6 CBY21094.1 - 7e-34 117.6 6.6 1.1e-31 110.5 4.2 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan TRM PF02005.16 CBY21094.1 - 0.21 10.7 0.7 0.29 10.3 0.7 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Cation_ATPase_C PF00689.21 CBY21095.1 - 5.4e-42 143.5 4.1 5.4e-42 143.5 4.1 3.1 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CBY21095.1 - 2e-30 105.6 18.8 2.3e-24 85.9 0.9 3.6 4 0 0 4 4 4 2 E1-E2 ATPase ATP_Ca_trans_C PF12424.8 CBY21095.1 - 1e-21 77.1 0.6 2.5e-21 75.9 0.6 1.7 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase PF13246.6 CBY21095.1 - 4.5e-18 65.1 0.1 1.1e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBY21095.1 - 1.2e-14 53.8 0.0 2.7e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CBY21095.1 - 3.2e-14 53.7 0.2 4.8e-11 43.3 0.1 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY21095.1 - 2.9e-07 30.5 0.2 4.2e-05 23.4 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase EI24 PF07264.11 CBY21095.1 - 0.0054 17.0 9.3 0.011 16.0 0.3 3.4 3 1 0 3 3 3 1 Etoposide-induced protein 2.4 (EI24) SepA PF17080.5 CBY21095.1 - 1.8 8.9 0.0 1.8 8.9 0.0 3.1 3 0 0 3 3 3 0 Multidrug Resistance efflux pump Epimerase PF01370.21 CBY21096.1 - 2.8e-55 187.4 0.0 3.8e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBY21096.1 - 4.3e-17 62.5 0.3 7.6e-17 61.7 0.0 1.4 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CBY21096.1 - 1.5e-06 27.5 0.0 3e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CBY21096.1 - 9.4e-05 21.7 1.4 0.00031 20.0 1.4 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CBY21096.1 - 0.00081 18.6 0.0 0.0017 17.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Pkinase PF00069.25 CBY21097.1 - 3.8e-15 56.0 0.0 1.7e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY21097.1 - 1e-08 34.4 0.0 1.5e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CBY21097.1 - 2.9e-07 30.0 0.1 0.0007 18.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase RRM_1 PF00076.22 CBY21098.1 - 1.1e-22 79.6 0.1 7.8e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY21098.1 - 5.2e-09 36.1 0.1 0.00059 19.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CBY21098.1 - 0.069 13.2 0.0 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif TPR_2 PF07719.17 CBY21099.1 - 1.7e-30 102.6 2.6 0.049 13.8 0.0 10.9 12 0 0 12 12 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 CBY21099.1 - 2.8e-24 83.9 13.6 0.013 15.3 0.0 11.3 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 CBY21099.1 - 5.1e-23 81.2 7.5 4.1e-05 23.8 0.0 8.0 7 1 3 10 10 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 CBY21099.1 - 4.4e-18 63.9 4.1 0.14 12.3 0.0 9.2 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 CBY21099.1 - 4.1e-17 61.6 5.5 0.37 11.5 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBY21099.1 - 1.9e-14 54.0 1.8 0.0023 18.5 0.0 7.4 5 4 4 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY21099.1 - 3.2e-14 51.9 9.9 0.0033 17.5 0.0 9.9 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY21099.1 - 4.7e-14 51.9 3.4 0.43 11.5 0.0 8.4 7 3 4 11 11 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY21099.1 - 1.3e-12 48.0 7.2 0.11 13.0 0.1 7.8 6 3 3 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBY21099.1 - 3.1e-12 46.0 8.9 0.00011 21.7 0.0 6.6 8 0 0 8 8 7 2 TPR repeat ANAPC3 PF12895.7 CBY21099.1 - 4.7e-08 33.2 10.6 1.6 9.0 0.0 6.1 5 1 1 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CBY21099.1 - 2.4e-07 30.4 7.3 2 8.4 0.0 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY21099.1 - 8.2e-06 25.8 4.7 7.7 7.1 0.1 6.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 CBY21099.1 - 2.3e-05 23.8 10.5 0.00087 18.6 0.3 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY21099.1 - 0.0003 20.9 0.5 4.7 7.4 0.0 4.9 4 1 2 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.10 CBY21099.1 - 0.00047 19.3 0.1 0.0029 16.7 0.0 2.3 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF3480 PF11979.8 CBY21099.1 - 0.0066 15.5 0.7 0.013 14.5 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) TPR_20 PF14561.6 CBY21099.1 - 0.01 16.1 3.2 26 5.2 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY21099.1 - 0.02 15.0 0.1 42 4.3 0.0 3.9 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat T2SSG PF08334.11 CBY21099.1 - 0.022 14.8 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G DUF2989 PF11207.8 CBY21099.1 - 0.032 14.0 6.5 1.6 8.5 0.0 3.7 5 0 0 5 5 4 0 Protein of unknown function (DUF2989) Hairy_orange PF07527.13 CBY21099.1 - 0.067 13.4 0.0 1.4 9.2 0.0 2.7 3 0 0 3 3 2 0 Hairy Orange DUF4810 PF16068.5 CBY21099.1 - 0.07 13.7 0.2 11 6.6 0.0 4.1 4 0 0 4 4 3 0 Domain of unknown function (DUF4810) BTAD PF03704.17 CBY21099.1 - 0.3 11.5 4.8 30 5.0 0.0 4.4 5 0 0 5 5 4 0 Bacterial transcriptional activator domain G8 PF10162.9 CBY21100.1 - 1.7e-13 50.7 0.0 3.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 CBY21100.1 - 0.0072 16.2 3.6 1.5 8.7 0.2 3.4 3 1 0 3 3 3 2 Right handed beta helix region Sec20 PF03908.13 CBY21101.1 - 6.2e-14 51.7 0.1 8e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Sec20 V-SNARE_C PF12352.8 CBY21101.1 - 0.0091 16.3 1.3 0.015 15.6 1.3 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF3270 PF11674.8 CBY21101.1 - 0.056 13.6 0.2 0.094 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Kinesin PF00225.23 CBY21102.1 - 2.2e-116 388.5 0.0 2.2e-116 388.5 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY21102.1 - 1.8e-26 92.8 0.0 3.7e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 CBY21102.1 - 0.0051 17.0 13.2 0.0062 16.7 12.3 1.6 1 1 0 1 1 1 1 Kinesin-associated V_ATPase_I PF01496.19 CBY21102.1 - 1.5 6.7 19.5 2.1 6.2 19.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Arf PF00025.21 CBY21103.1 - 5.6e-61 205.0 0.1 6.3e-61 204.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY21103.1 - 4.5e-14 52.7 0.0 6.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY21103.1 - 2.9e-12 46.5 0.0 3.5e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY21103.1 - 1.6e-09 37.4 0.3 0.00015 21.0 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY21103.1 - 3.3e-08 33.2 0.0 4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY21103.1 - 3.3e-08 33.2 0.0 4.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY21103.1 - 9.3e-07 28.9 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY21103.1 - 0.00015 21.4 0.0 0.0011 18.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CBY21103.1 - 0.00016 22.0 0.0 0.00031 21.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 CBY21103.1 - 0.0002 21.0 0.3 0.18 11.4 0.0 2.1 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBY21103.1 - 0.006 16.5 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CBY21103.1 - 0.0082 16.7 0.2 0.01 16.3 0.2 1.5 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 CBY21103.1 - 0.012 14.8 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Myosin_head PF00063.21 CBY21103.1 - 0.048 11.9 0.0 0.069 11.4 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) AAA_18 PF13238.6 CBY21103.1 - 0.058 14.0 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 CBY21103.1 - 0.07 12.0 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CBY21103.1 - 0.084 13.2 0.1 0.12 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 CBY21103.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CBY21103.1 - 0.089 12.7 1.8 1.3 8.9 0.5 2.1 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 CBY21103.1 - 0.12 12.3 0.3 0.22 11.4 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Thymidylate_kin PF02223.17 CBY21103.1 - 0.13 11.9 0.3 0.22 11.2 0.3 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_14 PF13173.6 CBY21103.1 - 0.14 12.2 0.2 1.7 8.7 0.1 2.1 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBY21103.1 - 0.14 11.9 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PPK2 PF03976.14 CBY21103.1 - 0.17 11.4 0.1 0.37 10.2 0.1 1.5 1 1 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) SRP54 PF00448.22 CBY21103.1 - 0.19 11.3 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.21 CBY21104.1 - 7.3e-62 207.9 0.2 8.1e-62 207.7 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY21104.1 - 5.2e-12 46.0 0.0 8.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY21104.1 - 9e-10 38.4 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBY21104.1 - 1.2e-09 37.8 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CBY21104.1 - 2.1e-09 37.0 0.7 0.00018 20.8 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY21104.1 - 9.1e-08 31.7 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY21104.1 - 6.1e-06 26.3 0.0 9.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY21104.1 - 5.6e-05 23.4 0.0 8.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CBY21104.1 - 0.0021 17.7 0.6 1.8 8.1 0.4 2.1 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBY21104.1 - 0.0049 16.8 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CBY21104.1 - 0.0077 16.8 0.2 0.01 16.4 0.2 1.5 1 1 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 CBY21104.1 - 0.0085 15.6 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 CBY21104.1 - 0.012 14.8 0.1 0.026 13.7 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 CBY21104.1 - 0.041 14.4 0.1 0.07 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain Myosin_head PF00063.21 CBY21104.1 - 0.045 12.0 0.0 0.064 11.5 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) AAA PF00004.29 CBY21104.1 - 0.077 13.4 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY21104.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CBY21104.1 - 0.087 12.7 1.9 1.3 8.9 0.5 2.1 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CBY21104.1 - 0.091 13.1 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 CBY21104.1 - 0.1 12.5 0.2 0.21 11.5 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Thymidylate_kin PF02223.17 CBY21104.1 - 0.12 12.0 0.3 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_24 PF13479.6 CBY21104.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBY21104.1 - 0.14 12.2 0.2 1.5 8.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain DLIC PF05783.11 CBY21104.1 - 0.17 10.7 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SRP54 PF00448.22 CBY21104.1 - 0.18 11.4 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PPK2 PF03976.14 CBY21104.1 - 0.18 11.2 0.2 0.36 10.3 0.1 1.5 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) HLH PF00010.26 CBY21105.1 - 2.2e-14 53.1 1.4 5.7e-14 51.8 1.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1122 PF06557.11 CBY21105.1 - 0.23 10.9 0.2 0.37 10.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) Lactonase PF10282.9 CBY21106.1 - 0.0035 16.7 0.0 0.019 14.2 0.0 2.0 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller HLH PF00010.26 CBY21107.1 - 5.6e-07 29.4 0.1 0.024 14.6 0.1 2.5 1 1 1 2 2 2 2 Helix-loop-helix DNA-binding domain DDE_Tnp_4 PF13359.6 CBY21107.1 - 0.089 12.5 1.2 0.6 9.8 0.2 2.1 1 1 1 2 2 2 0 DDE superfamily endonuclease Baculo_DNA_bind PF04786.12 CBY21107.1 - 0.16 11.3 0.5 0.27 10.5 0.1 1.5 2 0 0 2 2 2 0 ssDNA binding protein Babuvirus_MP PF07234.11 CBY21108.1 - 0.06 13.5 0.4 0.1 12.8 0.4 1.3 1 0 0 1 1 1 0 Movement and RNA silencing protein NitrOD5 PF11537.8 CBY21108.1 - 0.15 12.2 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 Astacin PF01400.24 CBY21110.1 - 1.3e-44 152.1 1.8 2.5e-44 151.2 1.8 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TSP_1 PF00090.19 CBY21110.1 - 9.7e-38 128.2 101.0 4.2e-09 36.5 13.9 7.6 6 0 0 6 6 6 5 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 CBY21110.1 - 3.8e-06 27.0 2.5 3.8e-06 27.0 2.5 4.7 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A EamA PF00892.20 CBY21111.1 - 0.12 12.5 38.8 0.094 12.9 12.1 4.0 2 2 0 2 2 2 0 EamA-like transporter family SLATT_5 PF18160.1 CBY21111.1 - 0.26 10.6 1.8 0.67 9.3 0.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 HRG PF16954.5 CBY21111.1 - 0.83 10.1 0.0 0.83 10.1 0.0 3.5 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene YrhK PF14145.6 CBY21111.1 - 2.1 8.3 13.7 2.3 8.1 1.4 3.3 2 1 1 3 3 3 0 YrhK-like protein Kelch_1 PF01344.25 CBY21112.1 - 8.3e-07 28.5 0.2 1.1 8.9 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 CBY21112.1 - 7e-05 22.7 1.6 0.96 9.5 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 CBY21112.1 - 0.00024 21.0 2.0 3.1 7.9 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY21112.1 - 0.00026 21.2 6.2 11 6.5 0.0 5.1 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CBY21112.1 - 0.028 14.4 0.4 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 CBY21112.1 - 0.36 11.2 3.6 2.1 8.7 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF3439 PF11921.8 CBY21113.1 - 0.00031 20.7 4.7 0.00041 20.3 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) MGC-24 PF05283.11 CBY21113.1 - 0.00044 20.7 2.5 0.00065 20.2 2.5 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin GTP_cyclohydroI PF01227.22 CBY21113.1 - 0.023 14.1 0.6 0.03 13.8 0.6 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase I Bacillus_HBL PF05791.11 CBY21113.1 - 0.062 13.1 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) SSP160 PF06933.11 CBY21113.1 - 0.096 10.9 12.5 0.12 10.6 12.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 CBY21113.1 - 3 5.7 6.2 3.5 5.5 6.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LETM1 PF07766.13 CBY21116.1 - 0.038 13.3 1.3 0.066 12.5 1.3 1.3 1 0 0 1 1 1 0 LETM1-like protein FeoB_Cyto PF17910.1 CBY21118.1 - 0.03 14.9 0.2 0.19 12.3 0.0 2.4 2 0 0 2 2 2 0 FeoB cytosolic helical domain Apolipoprotein PF01442.18 CBY21120.1 - 0.0064 16.4 0.0 0.009 15.9 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Tmemb_185A PF10269.9 CBY21120.1 - 0.0077 15.9 5.4 0.011 15.5 5.4 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Tape_meas_lam_C PF09718.10 CBY21120.1 - 0.013 15.6 3.7 7 6.9 0.6 3.1 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF4079 PF13301.6 CBY21120.1 - 0.043 14.0 0.1 0.078 13.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) T7SS_ESX_EspC PF10824.8 CBY21120.1 - 0.061 13.8 1.3 0.14 12.7 1.3 1.5 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm DUF3813 PF12758.7 CBY21120.1 - 0.12 12.8 0.1 5 7.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3813) MT0933_antitox PF14013.6 CBY21120.1 - 0.23 11.8 17.3 0.082 13.2 8.1 3.1 1 1 1 2 2 2 0 MT0933-like antitoxin protein Dodecin PF07311.12 CBY21120.1 - 0.27 11.5 3.2 0.51 10.6 0.8 2.5 1 1 1 2 2 2 0 Dodecin Acetyltransf_1 PF00583.25 CBY21121.1 - 1e-14 54.8 0.0 1.8e-14 54.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY21121.1 - 9.9e-10 38.7 0.0 2.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY21121.1 - 3.2e-07 30.3 0.0 5.7e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY21121.1 - 3.3e-07 30.2 0.0 5.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 CBY21121.1 - 0.01 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DUF4051 PF13260.6 CBY21121.1 - 0.31 10.8 2.4 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) FAM176 PF14851.6 CBY21122.1 - 0.0032 17.1 0.3 0.21 11.2 0.0 2.1 2 0 0 2 2 2 2 FAM176 family DUF1180 PF06679.12 CBY21122.1 - 0.0081 16.6 1.5 0.014 15.8 0.4 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1180) Syndecan PF01034.20 CBY21122.1 - 0.18 11.8 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain TPR_12 PF13424.6 CBY21123.1 - 4e-08 33.4 3.9 0.032 14.5 0.1 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY21123.1 - 0.0025 17.8 5.1 7.7 6.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY21123.1 - 0.016 16.0 1.1 32 5.7 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY21123.1 - 0.019 15.2 0.9 1.8 9.0 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY21123.1 - 0.066 13.3 0.2 4.3 7.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY21123.1 - 0.35 10.8 2.6 5.1 7.1 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY21123.1 - 2.5 8.4 6.6 3 8.1 1.7 3.3 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_6 PF12774.7 CBY21124.1 - 2.8e-160 532.7 0.1 2.5e-159 529.6 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBY21124.1 - 3.5e-142 474.2 12.4 3.5e-142 474.2 12.4 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBY21124.1 - 7.3e-111 370.3 0.0 2.2e-110 368.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBY21124.1 - 2.7e-103 344.8 0.6 8.5e-103 343.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CBY21124.1 - 2.7e-79 264.9 0.4 1.1e-75 253.1 0.0 3.8 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBY21124.1 - 1.8e-53 180.8 0.0 4.7e-53 179.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBY21124.1 - 2e-43 147.3 0.0 6.1e-43 145.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBY21124.1 - 1.1e-35 123.3 9.7 2.1e-35 122.4 9.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CBY21124.1 - 5.1e-31 107.4 0.0 2.4e-30 105.2 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBY21124.1 - 5.3e-19 68.3 0.0 1.4e-17 63.7 0.0 3.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CBY21124.1 - 4e-14 52.8 0.0 0.013 15.5 0.0 7.0 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA PF00004.29 CBY21124.1 - 0.0001 22.7 0.5 1.2 9.5 0.0 4.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBY21124.1 - 0.00016 22.2 0.5 0.03 14.9 0.0 4.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CBY21124.1 - 0.0089 16.4 0.1 49 4.4 0.0 4.2 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 CBY21124.1 - 0.058 13.9 0.0 50 4.4 0.0 3.6 3 0 0 3 3 3 0 ABC transporter Herpes_BTRF1 PF04682.12 CBY21124.1 - 0.079 12.3 0.1 0.26 10.6 0.1 1.8 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region T2SSE PF00437.20 CBY21124.1 - 0.08 12.0 4.1 0.74 8.8 0.1 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.6 CBY21124.1 - 0.083 13.2 1.5 50 4.2 0.0 4.4 5 0 0 5 5 4 0 AAA domain AAA_30 PF13604.6 CBY21124.1 - 0.1 12.3 1.3 7.4 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBY21124.1 - 0.14 11.6 1.7 0.62 9.5 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 CBY21124.1 - 0.33 10.3 2.4 6.7 6.0 0.0 3.5 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI R3H PF01424.22 CBY21125.1 - 1.3e-11 44.3 0.0 3.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CBY21125.1 - 1.7e-10 40.7 119.1 0.00015 21.7 12.3 14.5 15 2 1 16 16 16 8 NF-X1 type zinc finger HopA1 PF17914.1 CBY21125.1 - 0.42 10.3 1.8 78 3.0 0.2 3.3 3 0 0 3 3 3 0 HopA1 effector protein family PAM2 PF07145.15 CBY21125.1 - 0.55 10.1 6.5 0.29 10.9 1.7 2.4 1 1 1 2 2 2 0 Ataxin-2 C-terminal region DHC_N1 PF08385.12 CBY21126.1 - 5e-113 378.7 11.3 5e-113 378.7 11.3 2.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 Dynein_C PF18199.1 CBY21126.1 - 5.9e-96 321.3 0.1 5.2e-95 318.2 0.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBY21126.1 - 1.7e-90 302.9 0.0 1.4e-89 299.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBY21126.1 - 1.1e-85 286.2 3.0 1.3e-84 282.8 0.7 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBY21126.1 - 8.4e-62 207.9 1.9 1.1e-61 207.4 0.0 2.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBY21126.1 - 1.2e-50 171.5 0.1 2.8e-50 170.3 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CBY21126.1 - 6e-49 166.9 7.7 6e-49 166.9 7.7 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CBY21126.1 - 4.8e-40 136.4 0.0 1.7e-39 134.6 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CBY21126.1 - 1.9e-20 73.2 0.1 1.5e-19 70.4 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBY21126.1 - 6.4e-17 61.6 0.6 4.7e-15 55.6 0.0 3.6 3 0 0 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 CBY21126.1 - 5.2e-12 45.9 0.0 7.8e-06 25.9 0.0 3.7 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY21126.1 - 0.00024 21.5 0.4 0.037 14.4 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 CBY21126.1 - 0.0023 17.7 0.0 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 CBY21126.1 - 0.0026 18.2 0.0 0.056 13.9 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY21126.1 - 0.015 15.6 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBY21126.1 - 0.029 14.4 0.0 0.13 12.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CBY21126.1 - 0.043 13.0 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 CBY21126.1 - 0.083 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 CBY21126.1 - 0.14 11.9 0.3 7 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain MscS_porin PF12795.7 CBY21126.1 - 1 8.8 6.8 4.6 6.7 2.0 3.4 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain ParA PF10609.9 CBY21127.1 - 3e-85 285.6 0.1 3.5e-85 285.4 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBY21127.1 - 2.1e-13 50.4 0.0 2.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CBY21127.1 - 9.5e-09 34.8 0.1 2e-05 24.0 0.0 2.3 2 1 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 CBY21127.1 - 2.3e-08 34.1 0.0 1.6e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY21127.1 - 0.00099 19.5 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MipZ PF09140.11 CBY21127.1 - 0.0014 18.0 0.0 0.0025 17.1 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ RsgA_GTPase PF03193.16 CBY21127.1 - 0.0021 18.0 0.5 0.0055 16.6 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CBY21127.1 - 0.0034 17.0 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY21127.1 - 0.0034 17.9 0.0 0.0057 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBY21127.1 - 0.0056 16.0 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_26 PF13500.6 CBY21127.1 - 0.014 15.3 0.0 6.2 6.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBY21127.1 - 0.027 13.6 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CBP_BcsQ PF06564.12 CBY21127.1 - 0.029 13.9 0.0 0.32 10.4 0.0 2.0 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RNA_helicase PF00910.22 CBY21127.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CLP1_P PF16575.5 CBY21127.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ABC_tran PF00005.27 CBY21127.1 - 0.083 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 CBY21127.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 CBY21127.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 CBY21127.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF3016 PF11454.8 CBY21127.1 - 0.2 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) BP28CT PF08146.12 CBY21128.1 - 2.3e-27 95.8 0.1 8.7e-27 93.9 0.1 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain RTP1_C1 PF10363.9 CBY21128.1 - 0.0005 20.2 7.5 0.39 10.9 0.1 5.7 6 0 0 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CBY21128.1 - 0.014 15.9 8.7 0.58 10.7 0.1 6.6 8 0 0 8 8 8 0 HEAT-like repeat HEAT PF02985.22 CBY21128.1 - 0.052 13.8 6.1 0.82 10.1 0.1 5.2 6 0 0 6 6 6 0 HEAT repeat FERM_N_2 PF18038.1 CBY21128.1 - 0.13 13.1 0.2 6.1 7.7 0.0 3.3 3 0 0 3 3 3 0 FERM N-terminal domain HEAT_2 PF13646.6 CBY21128.1 - 0.19 12.1 8.5 0.57 10.6 0.1 5.1 6 0 0 6 6 6 0 HEAT repeats CEP1-DNA_bind PF09287.10 CBY21129.1 - 0.13 11.8 0.3 0.33 10.6 0.3 1.6 1 0 0 1 1 1 0 CEP-1, DNA binding RTP1_C1 PF10363.9 CBY21129.1 - 0.16 12.2 4.0 0.4 10.9 0.2 3.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cupin_8 PF13621.6 CBY21131.1 - 8.8e-55 186.2 1.3 1.2e-54 185.7 1.3 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CBY21131.1 - 0.0061 17.0 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase D123 PF07065.14 CBY21132.1 - 3.5e-63 213.6 0.1 4.1e-63 213.4 0.1 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 CBY21132.1 - 0.047 13.7 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 DUF2805 PF10985.8 CBY21132.1 - 0.16 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) 2OG-FeII_Oxy_2 PF13532.6 CBY21133.1 - 5.4e-05 23.5 0.0 0.00014 22.1 0.0 1.7 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3898 PF13037.6 CBY21133.1 - 0.087 12.9 0.1 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3898) DHODB_Fe-S_bind PF10418.9 CBY21133.1 - 0.16 11.8 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 2OG-FeII_Oxy PF03171.20 CBY21133.1 - 0.17 12.4 0.0 0.75 10.3 0.0 2.1 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF3656 PF12392.8 CBY21133.1 - 0.53 10.9 3.6 1.5 9.5 2.8 2.2 2 0 0 2 2 2 0 Collagenase TMEM214 PF10151.9 CBY21133.1 - 6.6 5.1 10.8 10 4.5 10.8 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator HSP20 PF00011.21 CBY21134.1 - 0.00023 21.3 0.7 0.00042 20.4 0.7 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Nucleoporin_FG PF13634.6 CBY21134.1 - 0.072 13.9 2.5 0.15 13.0 2.5 1.5 1 0 0 1 1 1 0 Nucleoporin FG repeat region ELFV_dehydrog_N PF02812.18 CBY21135.1 - 3.3e-57 192.0 0.1 6.5e-57 191.0 0.1 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 CBY21135.1 - 2.2e-48 165.1 0.0 1.1e-45 156.2 0.0 2.5 2 1 1 3 3 3 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SelR PF01641.18 CBY21136.1 - 0.0021 18.1 0.2 0.011 15.8 0.2 2.2 1 1 0 1 1 1 1 SelR domain SelR PF01641.18 CBY21137.1 - 0.00098 19.2 0.4 0.0047 17.0 0.3 2.2 1 1 0 1 1 1 1 SelR domain tRNA_NucTran2_2 PF13735.6 CBY21139.1 - 0.014 15.4 0.1 0.015 15.3 0.1 1.0 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DIT1_PvcA PF05141.12 CBY21140.1 - 0.5 9.8 5.4 0.79 9.1 5.4 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein SPT6_acidic PF14632.6 CBY21140.1 - 9.8 6.8 22.2 21 5.8 18.8 2.4 1 1 1 2 2 2 0 Acidic N-terminal SPT6 tRNA_NucTran2_2 PF13735.6 CBY21142.1 - 0.014 15.4 0.1 0.015 15.3 0.1 1.0 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative GAS PF13851.6 CBY21143.1 - 0.0048 16.3 19.8 0.0048 16.3 19.8 5.3 1 1 2 5 5 5 2 Growth-arrest specific micro-tubule binding 7tm_1 PF00001.21 CBY21144.1 - 3.3e-32 111.9 11.2 4e-32 111.6 11.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CBY21144.1 - 1.2e-13 51.3 14.8 1.6e-13 50.9 14.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CBY21144.1 - 2.6e-06 27.0 14.1 4.3e-06 26.3 14.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 CBY21144.1 - 7.6e-05 22.2 14.6 0.00011 21.6 14.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 CBY21144.1 - 0.0084 15.9 3.0 0.013 15.3 3.0 1.2 1 0 0 1 1 1 1 Olfactory receptor PhoLip_ATPase_C PF16212.5 CBY21145.1 - 1.1e-63 215.4 24.3 1.1e-63 215.4 24.3 3.0 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBY21145.1 - 2.1e-22 78.6 3.9 2.1e-22 78.6 3.9 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CBY21145.1 - 1.7e-10 40.8 0.0 4.2e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBY21145.1 - 1.9e-09 37.3 0.4 5.7e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBY21145.1 - 1.3e-08 35.4 1.9 1.3e-05 25.6 1.1 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY21145.1 - 0.012 15.4 0.4 0.052 13.3 0.4 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TcdA_TcdB_pore PF12920.7 CBY21145.1 - 0.072 11.3 0.1 0.12 10.7 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain CLPTM1 PF05602.12 CBY21146.1 - 7.5e-87 292.1 0.1 1.5e-86 291.1 0.1 1.5 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CBY21146.1 - 0.01 15.6 0.3 0.92 9.3 0.0 2.7 2 0 0 2 2 2 0 PQ loop repeat Proteasome PF00227.26 CBY21147.1 - 8.1e-48 162.4 0.3 9.7e-48 162.2 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit RsfS PF02410.15 CBY21148.1 - 5.4e-19 68.5 0.0 1.7e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation BTB PF00651.31 CBY21149.1 - 2e-29 102.1 2.2 3.6e-29 101.2 0.5 2.1 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 CBY21149.1 - 3.7e-07 30.3 0.7 1.2e-06 28.7 0.4 2.0 2 0 0 2 2 2 1 MATH domain BACK PF07707.15 CBY21149.1 - 0.0013 18.8 0.5 0.2 11.8 0.0 3.6 3 1 1 4 4 4 1 BTB And C-terminal Kelch Prefoldin_2 PF01920.20 CBY21150.1 - 8.9e-21 73.8 2.6 1e-20 73.6 2.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit DivIVA PF05103.13 CBY21150.1 - 0.06 13.4 0.8 9.4 6.3 0.0 2.1 2 0 0 2 2 2 0 DivIVA protein Nsp1_C PF05064.13 CBY21150.1 - 0.3 10.9 2.4 3.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region dUTPase PF00692.19 CBY21151.1 - 7.7e-39 132.3 0.0 8.9e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF3037 PF11236.8 CBY21151.1 - 0.051 14.0 0.0 0.087 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Erp_C PF06780.11 CBY21152.1 - 0.038 14.0 3.4 0.049 13.6 3.4 1.1 1 0 0 1 1 1 0 Erp protein C-terminus V_ATPase_I PF01496.19 CBY21152.1 - 0.56 8.0 3.7 0.54 8.1 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_B PF00052.18 CBY21153.1 - 2.1e-62 209.0 0.0 8.4e-25 87.2 0.0 3.4 3 0 0 3 3 3 3 Laminin B (Domain IV) Ig_3 PF13927.6 CBY21153.1 - 1.2e-29 102.8 6.0 2.3e-16 60.2 1.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CBY21153.1 - 2.3e-26 91.7 0.0 6.4e-16 58.2 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain VWA PF00092.28 CBY21153.1 - 5.6e-20 72.3 1.0 9.8e-20 71.5 1.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ig_2 PF13895.6 CBY21153.1 - 1e-19 70.6 1.1 7.2e-09 35.9 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ldl_recept_a PF00057.18 CBY21153.1 - 1.6e-19 69.8 52.4 5.1e-10 39.4 12.8 6.9 7 0 0 7 7 3 3 Low-density lipoprotein receptor domain class A ig PF00047.25 CBY21153.1 - 3e-15 56.2 0.1 1.7e-08 34.5 0.1 2.9 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CBY21153.1 - 1.1e-09 38.5 8.3 0.028 14.6 0.5 5.3 4 2 1 5 5 5 3 Immunoglobulin V-set domain VWA_2 PF13519.6 CBY21153.1 - 1.5e-06 28.8 0.3 4.7e-06 27.2 0.3 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_EGF PF00053.24 CBY21153.1 - 1.7e-06 28.1 53.0 1.8e-05 24.8 17.2 9.7 7 4 3 10 10 7 5 Laminin EGF domain C2-set_2 PF08205.12 CBY21153.1 - 0.00045 20.2 0.3 0.82 9.8 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 CBY21154.1 - 6.7e-32 109.9 8.2 1.6e-07 31.9 0.0 8.8 8 1 0 8 8 8 5 Immunoglobulin domain Ig_2 PF13895.6 CBY21154.1 - 4e-30 104.0 0.6 4.1e-10 39.8 0.0 7.7 8 0 0 8 8 8 4 Immunoglobulin domain ig PF00047.25 CBY21154.1 - 1.6e-24 85.8 14.6 8.7e-05 22.6 0.1 10.1 9 3 1 10 10 10 4 Immunoglobulin domain I-set PF07679.16 CBY21154.1 - 2.1e-21 75.8 6.2 0.00014 21.9 0.0 9.3 8 3 0 8 8 8 3 Immunoglobulin I-set domain Ig_5 PF16681.5 CBY21154.1 - 1.2e-14 54.5 5.1 0.0016 18.8 0.0 5.7 6 1 0 6 6 6 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CBY21154.1 - 4.6e-14 52.4 4.3 0.00052 20.2 0.1 5.3 6 0 0 6 6 5 3 T-cell surface glycoprotein CD3 delta chain Laminin_G_2 PF02210.24 CBY21154.1 - 5.1e-14 52.9 0.2 1.3e-13 51.6 0.1 1.8 2 0 0 2 2 2 1 Laminin G domain V-set PF07686.17 CBY21154.1 - 3.6e-13 49.6 2.8 8.9e-06 25.9 0.0 6.5 6 1 1 7 7 7 2 Immunoglobulin V-set domain Laminin_G_1 PF00054.23 CBY21154.1 - 7.6e-08 32.6 0.1 4.6e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 Laminin G domain Ig_6 PF18452.1 CBY21154.1 - 1e-07 31.4 0.2 0.73 9.4 0.0 4.6 5 0 0 5 5 5 3 Immunoglobulin domain Izumo-Ig PF16706.5 CBY21154.1 - 0.00047 20.2 0.0 1.4 9.0 0.0 4.4 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain CBM_15 PF03426.14 CBY21154.1 - 0.04 13.5 0.4 5.2 6.6 0.1 3.2 4 0 0 4 4 4 0 Carbohydrate binding domain (family 15) C2-set PF05790.15 CBY21154.1 - 0.13 12.5 0.0 3.7 7.8 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin C2-set domain DUF3581 PF12119.8 CBY21154.1 - 0.16 11.4 0.0 6.7 6.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3581) CBM_14 PF01607.24 CBY21155.1 - 5.3e-13 48.9 4.3 6.6e-13 48.6 3.8 1.6 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain 7tm_1 PF00001.21 CBY21156.1 - 1.6e-15 57.2 0.6 1.7e-15 57.1 0.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CBY21156.1 - 0.042 13.2 0.5 0.05 13.0 0.5 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Pox_D5 PF03288.16 CBY21158.1 - 0.063 13.8 0.2 0.28 11.7 0.1 2.0 2 0 0 2 2 2 0 Poxvirus D5 protein-like RVT_1 PF00078.27 CBY21159.1 - 5.2e-26 91.5 0.0 1.4e-25 90.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRAM_LAG1_CLN8 PF03798.16 CBY21160.1 - 1.7e-05 24.7 5.0 2.3e-05 24.2 5.0 1.2 1 0 0 1 1 1 1 TLC domain FdhD-NarQ PF02634.15 CBY21160.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 FdhD/NarQ family PID PF00640.23 CBY21162.1 - 2.5e-14 53.5 0.1 6.2e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) NumbF PF06311.12 CBY21162.1 - 3.8e-05 24.1 0.4 0.00021 21.8 0.0 2.4 2 0 0 2 2 2 1 NUMB domain Ank_2 PF12796.7 CBY21163.1 - 2.8e-24 85.5 4.3 3.8e-12 46.6 0.9 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY21163.1 - 3.3e-24 84.9 6.6 2.7e-13 50.1 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY21163.1 - 4.4e-24 84.2 1.7 3e-08 33.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY21163.1 - 3.8e-20 71.4 2.4 1.2e-07 31.9 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CBY21163.1 - 1.1e-18 65.3 1.2 4.5e-05 23.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DsrH PF04077.12 CBY21163.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 DsrH like protein Dpy19 PF10034.9 CBY21164.1 - 3.2e-204 679.9 10.5 3.7e-204 679.7 10.5 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Vma12 PF11712.8 CBY21166.1 - 0.15 12.2 0.2 0.55 10.3 0.2 1.9 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ArfGap PF01412.18 CBY21167.1 - 1.3e-23 83.3 0.4 3.9e-23 81.7 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GIT_SHD PF08518.11 CBY21167.1 - 1.2e-13 50.5 1.1 1.9e-09 37.0 0.2 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Ank_2 PF12796.7 CBY21167.1 - 0.0042 17.7 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY21167.1 - 0.0061 17.0 0.1 0.012 16.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat PDCD2_C PF04194.13 CBY21167.1 - 0.0066 16.5 2.2 0.012 15.7 2.2 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Ank_5 PF13857.6 CBY21167.1 - 0.012 15.9 0.1 0.023 15.0 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) GrpE PF01025.19 CBY21167.1 - 0.015 14.9 4.8 0.16 11.7 2.6 2.3 2 0 0 2 2 2 0 GrpE Ank_4 PF13637.6 CBY21167.1 - 0.029 14.9 0.1 0.15 12.6 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) GIT_CC PF16559.5 CBY21167.1 - 0.059 13.2 0.6 0.12 12.2 0.6 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Prominin PF05478.11 CBY21167.1 - 0.17 9.8 0.6 0.26 9.2 0.6 1.2 1 0 0 1 1 1 0 Prominin FadA PF09403.10 CBY21167.1 - 3.7 8.1 9.7 0.42 11.1 4.0 2.4 3 0 0 3 3 3 0 Adhesion protein FadA Ribosomal_S18 PF01084.20 CBY21168.1 - 4.7e-09 36.3 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 CN_hydrolase PF00795.22 CBY21169.1 - 4.1e-50 170.6 0.0 4.7e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Snf7 PF03357.21 CBY21170.1 - 9e-41 139.3 25.3 1.1e-40 139.1 25.3 1.0 1 0 0 1 1 1 1 Snf7 Phage_TAC_2 PF06894.11 CBY21170.1 - 0.043 13.6 1.4 0.077 12.8 1.4 1.4 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G GPP34 PF05719.11 CBY21170.1 - 0.061 13.4 2.3 0.1 12.6 2.3 1.4 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) DUF4363 PF14276.6 CBY21170.1 - 0.32 11.1 9.9 0.56 10.4 4.3 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4363) Exonuc_VII_L PF02601.15 CBY21170.1 - 0.42 10.1 10.3 0.54 9.8 10.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snf7 PF03357.21 CBY21171.1 - 4.6e-39 133.8 18.8 6.3e-39 133.3 18.8 1.3 1 1 0 1 1 1 1 Snf7 V_ATPase_I PF01496.19 CBY21171.1 - 0.13 10.1 4.4 0.16 9.8 4.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 CBY21171.1 - 0.88 9.7 8.5 3.7 7.7 0.5 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TraF_2 PF13729.6 CBY21171.1 - 1.4 8.3 6.3 0.92 8.8 4.2 1.7 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DUF2203 PF09969.9 CBY21171.1 - 8.7 7.1 7.1 16 6.2 0.3 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Snf7 PF03357.21 CBY21172.1 - 5.7e-46 156.3 18.7 7.8e-46 155.8 18.7 1.2 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.12 CBY21172.1 - 0.011 16.1 5.8 0.016 15.6 5.8 1.2 1 0 0 1 1 1 0 SYF2 splicing factor DUF1869 PF08956.10 CBY21172.1 - 0.036 14.0 0.9 0.088 12.7 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) DUF5401 PF17380.2 CBY21172.1 - 0.049 11.7 2.9 0.054 11.6 2.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) STATa_Ig PF18214.1 CBY21172.1 - 3.1 7.8 7.5 0.51 10.4 3.4 1.8 2 1 0 2 2 2 0 STATa Immunoglobulin-like domain Tristanin_u2 PF16638.5 CBY21172.1 - 8.2 7.3 10.9 56 4.6 10.9 2.1 1 1 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers DUF842 PF05811.13 CBY21173.1 - 3.4e-13 49.4 10.4 4.5e-13 49.0 10.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF725 PF05267.12 CBY21173.1 - 0.0073 16.3 1.9 0.01 15.8 0.8 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF725) DUF5112 PF17139.4 CBY21173.1 - 0.011 15.2 0.6 0.013 15.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) Spore_III_AB PF09548.10 CBY21173.1 - 0.017 15.2 1.2 0.021 14.9 1.2 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ERp29 PF07749.12 CBY21173.1 - 0.087 13.7 1.6 0.23 12.4 0.3 2.0 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain NPV_P10 PF05531.12 CBY21173.1 - 0.11 13.0 1.5 4.7 7.7 0.5 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4456 PF14644.6 CBY21173.1 - 0.12 12.1 4.5 3.3 7.3 2.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4456) Mod_r PF07200.13 CBY21173.1 - 0.13 12.3 2.0 0.17 12.0 2.0 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.14 CBY21173.1 - 4 7.8 9.2 27 5.1 9.2 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 CBY21174.1 - 1.3e-50 172.2 0.9 2.3e-50 171.4 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21174.1 - 1.2e-35 123.0 0.8 2.9e-35 121.8 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBY21174.1 - 0.0004 20.4 0.0 0.53 10.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY21174.1 - 0.021 13.6 0.1 0.11 11.3 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 CBY21174.1 - 0.032 13.6 0.3 0.12 11.7 0.0 2.1 3 0 0 3 3 3 0 Kinase-like MKT1_C PF12246.8 CBY21174.1 - 0.033 13.4 0.2 0.097 11.9 0.2 1.8 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication PRP9_N PF16958.5 CBY21174.1 - 0.98 9.4 4.0 17 5.4 0.0 3.0 3 0 0 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus CUE PF02845.16 CBY21175.1 - 4.7e-06 26.2 0.1 1.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 CBY21175.1 - 0.019 14.6 0.6 0.04 13.6 0.6 1.5 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) UBA PF00627.31 CBY21176.1 - 7.8e-08 32.1 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF1421 PF07223.11 CBY21176.1 - 0.091 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Lipoprotein_Ltp PF07553.11 CBY21177.1 - 0.0033 17.7 0.2 0.0076 16.5 0.2 1.6 1 0 0 1 1 1 1 Host cell surface-exposed lipoprotein TPR_2 PF07719.17 CBY21178.1 - 2.7e-10 39.6 0.9 0.0023 17.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY21178.1 - 1e-08 34.7 0.9 1.2e-07 31.2 0.1 2.3 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.28 CBY21178.1 - 1.4e-08 34.2 0.7 0.00012 21.8 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY21178.1 - 1.5e-07 31.1 0.3 0.0068 16.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY21178.1 - 4.8e-05 23.8 2.8 0.15 12.6 0.9 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY21178.1 - 6.5e-05 23.4 1.7 4.7 8.3 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY21178.1 - 9e-05 23.0 0.2 0.0022 18.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBY21178.1 - 0.0011 18.2 1.9 0.26 10.4 0.5 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY21178.1 - 0.0055 16.8 0.3 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY21178.1 - 0.0065 16.8 0.2 0.02 15.2 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY21178.1 - 0.024 14.6 2.9 3.1 8.0 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Cytochrom_D1 PF02239.16 CBY21178.1 - 0.092 11.3 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain TPR_12 PF13424.6 CBY21178.1 - 0.12 12.7 1.1 9.4 6.6 0.1 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY21178.1 - 0.29 11.1 0.9 15 5.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CBY21178.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.8 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain PMP22_Claudin PF00822.20 CBY21179.1 - 3.8e-15 56.2 2.2 5.2e-15 55.7 1.7 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Sensor PF13796.6 CBY21179.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.5 1 1 0 1 1 1 0 Putative sensor TMEM37 PF15108.6 CBY21179.1 - 0.044 13.7 0.8 0.054 13.4 0.8 1.2 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family Clc-like PF07062.12 CBY21179.1 - 0.071 12.6 0.4 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Clc-like TMEM174 PF15029.6 CBY21179.1 - 0.096 12.4 1.2 0.18 11.5 1.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 Claudin_2 PF13903.6 CBY21179.1 - 3.2 7.5 7.5 17 5.1 7.5 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3050 PF11251.8 CBY21180.1 - 0.0015 18.2 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Trypsin PF00089.26 CBY21182.1 - 6.8e-29 101.2 1.9 8e-29 101.0 1.9 1.1 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 CBY21183.1 - 2.4e-06 27.8 0.1 5.6e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 CUB domain Phospholip_B PF04916.13 CBY21186.1 - 2.1e-157 524.9 0.9 2.6e-157 524.6 0.9 1.0 1 0 0 1 1 1 1 Phospholipase B PDZ PF00595.24 CBY21187.1 - 3.2e-12 46.6 0.4 7.1e-12 45.5 0.4 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_5 PF17817.1 CBY21187.1 - 4.7e-11 42.8 0.0 2.4e-10 40.5 0.0 2.3 1 0 0 1 1 1 1 PDZ domain SAM_1 PF00536.30 CBY21187.1 - 6.6e-06 26.5 0.3 1.3e-05 25.6 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY21187.1 - 1.8e-05 24.8 0.3 3.6e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 CBY21187.1 - 1.8e-05 24.5 0.0 4.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY21187.1 - 0.00029 21.1 0.1 0.00066 20.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DUF724 PF05266.14 CBY21187.1 - 0.003 17.4 0.3 0.003 17.4 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF724) JIP_LZII PF16471.5 CBY21187.1 - 0.022 14.9 3.7 0.022 14.9 3.7 2.4 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 CBY21187.1 - 0.032 14.7 3.7 0.032 14.7 3.7 3.0 4 0 0 4 4 3 0 Cell division protein ZapB Use1 PF09753.9 CBY21187.1 - 0.23 11.1 10.1 0.48 10.1 10.1 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 KCT2 PF17818.1 CBY21187.1 - 0.27 11.3 2.5 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 Keratinocyte-associated gene product DUF87 PF01935.17 CBY21187.1 - 0.43 10.6 5.0 1 9.4 5.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain YabA PF06156.13 CBY21187.1 - 8.4 7.1 10.6 1.7 9.3 1.8 2.9 2 1 1 3 3 3 0 Initiation control protein YabA Med18 PF09637.10 CBY21188.1 - 4.1e-26 92.3 0.0 7.9e-19 68.5 0.0 2.1 1 1 1 2 2 2 2 Med18 protein Cyclin_N PF00134.23 CBY21189.1 - 6.3e-33 113.2 3.8 6.3e-33 113.2 3.8 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY21189.1 - 1.5e-21 76.7 1.1 1.5e-21 76.7 1.1 2.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain TPR_8 PF13181.6 CBY21190.1 - 2.4 8.6 5.0 16 6.0 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 CBY21191.1 - 0.00026 21.1 0.2 0.00027 21.0 0.2 1.1 1 0 0 1 1 1 1 DnaJ domain RT_RNaseH_2 PF17919.1 CBY21191.1 - 0.019 15.0 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase FG-GAP PF01839.23 CBY21192.1 - 2.5e-19 69.1 0.4 4.2e-11 42.8 0.4 2.7 2 0 0 2 2 2 2 FG-GAP repeat Integrin_alpha2 PF08441.12 CBY21192.1 - 1e-10 41.1 0.1 4.4e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 Integrin alpha VCBS PF13517.6 CBY21192.1 - 1.5e-07 31.9 0.1 0.0037 17.8 0.1 2.8 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 CBY21192.1 - 0.0012 19.1 1.2 4.5 7.6 0.0 3.9 3 0 0 3 3 3 2 FG-GAP repeat PsbJ PF01788.17 CBY21192.1 - 0.1 12.5 0.6 0.21 11.5 0.6 1.5 1 0 0 1 1 1 0 PsbJ MFS_1 PF07690.16 CBY21193.1 - 2.3e-33 115.6 28.1 3.9e-31 108.3 23.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C24 PF03510.14 CBY21194.1 - 0.033 14.7 0.1 0.58 10.7 0.0 2.8 2 0 0 2 2 2 0 2C endopeptidase (C24) cysteine protease family Sushi PF00084.20 CBY21194.1 - 0.053 14.1 0.6 0.053 14.1 0.6 8.7 8 0 0 8 8 8 0 Sushi repeat (SCR repeat) Mitofilin PF09731.9 CBY21194.1 - 0.76 8.5 17.5 1 8.1 17.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mpp10 PF04006.12 CBY21194.1 - 1.6 7.0 20.4 2.2 6.6 20.4 1.1 1 0 0 1 1 1 0 Mpp10 protein API5 PF05918.11 CBY21194.1 - 3.8 6.2 11.9 5.7 5.6 11.9 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) LPP20 PF02169.16 CBY21194.1 - 8.5 6.8 10.4 3.8 7.9 7.1 2.2 2 0 0 2 2 2 0 LPP20 lipoprotein RVT_1 PF00078.27 CBY21195.1 - 7.9e-26 90.9 0.0 1.9e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CBY21195.1 - 4e-05 23.4 0.0 0.0003 20.6 0.0 2.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CBY21195.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family ADAM_CR_2 PF17771.1 CBY21197.1 - 1.6 9.3 7.9 0.058 13.9 1.1 2.0 3 0 0 3 3 3 0 ADAM cysteine-rich domain Voltage_CLC PF00654.20 CBY21198.1 - 4.6e-97 325.4 19.8 4.6e-97 325.4 19.8 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBY21198.1 - 8.9e-14 51.7 0.0 3.6e-08 33.7 0.0 3.0 3 0 0 3 3 3 2 CBS domain p450 PF00067.22 CBY21199.1 - 6.8e-55 186.6 0.4 8e-55 186.4 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_4 PF17784.1 CBY21200.1 - 2.5e-46 158.2 0.6 3e-46 158.0 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY21200.1 - 0.00071 20.0 0.3 0.0045 17.4 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase family Ribonuclease_T2 PF00445.18 CBY21200.1 - 0.084 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease T2 family Myb_DNA-bind_2 PF08914.11 CBY21200.1 - 0.14 12.4 0.9 6.8 6.9 0.4 2.5 2 0 0 2 2 2 0 Rap1 Myb domain ABC_membrane PF00664.23 CBY21201.1 - 2.7e-52 178.1 29.3 2e-33 116.2 7.7 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY21201.1 - 8.3e-52 175.3 0.8 3.3e-29 102.2 0.3 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBY21201.1 - 5.2e-11 42.4 8.9 0.013 15.0 3.7 4.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBY21201.1 - 2.7e-07 30.2 0.9 0.0072 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CBY21201.1 - 1.2e-06 28.6 8.5 0.028 14.2 0.2 3.9 4 1 1 5 5 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBY21201.1 - 1.7e-06 28.6 1.2 0.079 13.5 0.1 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CBY21201.1 - 2.6e-06 27.5 0.6 0.032 14.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY21201.1 - 1.6e-05 24.9 0.3 0.087 12.7 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 CBY21201.1 - 5.9e-05 23.3 2.2 0.0015 18.7 0.2 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 CBY21201.1 - 0.00011 22.7 0.2 0.72 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBY21201.1 - 0.00056 20.2 0.5 0.12 12.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 CBY21201.1 - 0.0016 17.7 0.5 0.17 11.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 CBY21201.1 - 0.0017 17.6 0.3 0.04 13.2 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 CBY21201.1 - 0.0025 18.3 0.2 1.9 9.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CBY21201.1 - 0.0034 17.5 1.2 1.2 9.2 0.2 2.5 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.18 CBY21201.1 - 0.0034 16.8 0.6 0.074 12.4 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CBY21201.1 - 0.0057 16.2 0.2 0.2 11.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 CBY21201.1 - 0.0082 15.4 1.7 1.5 7.9 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Rad17 PF03215.15 CBY21201.1 - 0.011 15.7 1.0 2.8 7.8 0.0 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain AIG1 PF04548.16 CBY21201.1 - 0.012 14.9 0.1 0.06 12.7 0.1 2.1 2 0 0 2 2 2 0 AIG1 family Yip1 PF04893.17 CBY21201.1 - 0.017 14.8 0.4 0.017 14.8 0.4 4.9 5 2 1 6 6 4 0 Yip1 domain NACHT PF05729.12 CBY21201.1 - 0.018 15.0 0.1 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 CBY21201.1 - 0.027 14.1 0.6 0.9 9.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CBY21201.1 - 0.029 14.4 0.4 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CBY21201.1 - 0.16 11.0 0.1 18 4.2 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 CBY21201.1 - 0.17 10.9 0.3 4.6 6.1 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 CBY21201.1 - 0.18 10.7 0.6 1.2 7.9 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 CBY21201.1 - 1.5 8.5 7.7 0.25 11.0 0.2 2.6 3 0 0 3 3 3 0 AAA ATPase domain SNN_transmemb PF09049.10 CBY21201.1 - 2.4 8.1 5.1 22 5.1 4.0 2.7 2 0 0 2 2 2 0 Stannin transmembrane Ion_trans PF00520.31 CBY21202.1 - 4.4e-06 26.1 4.4 5.5e-06 25.8 4.4 1.1 1 0 0 1 1 1 1 Ion transport protein SLAC1 PF03595.17 CBY21202.1 - 0.075 12.3 4.7 0.044 13.0 3.0 1.4 1 1 0 1 1 1 0 Voltage-dependent anion channel Cullin PF00888.22 CBY21204.1 - 1.9e-61 208.5 5.6 2.3e-61 208.2 5.6 1.0 1 0 0 1 1 1 1 Cullin family DUF3740 PF12548.8 CBY21204.1 - 0.69 10.3 4.2 18 5.7 1.0 2.6 2 1 0 2 2 2 0 Sulfatase protein Cullin PF00888.22 CBY21205.1 - 4.8e-82 276.5 10.4 7.4e-82 275.9 10.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBY21205.1 - 2.4e-25 88.4 0.9 8.1e-25 86.6 0.9 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain MalF_P2 PF14785.6 CBY21205.1 - 0.024 14.7 1.2 0.074 13.1 0.4 2.1 2 0 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain RT_RNaseH PF17917.1 CBY21208.1 - 5.3e-30 103.8 0.0 9.9e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY21208.1 - 3.3e-28 97.6 0.0 6e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY21208.1 - 6e-20 71.6 0.0 1.4e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY21208.1 - 1.6e-11 44.1 0.3 4e-11 42.8 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CBY21208.1 - 0.002 17.7 0.0 0.5 9.8 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 CBY21208.1 - 0.041 13.7 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 Reverse transcriptase thumb domain DUF1834 PF08873.11 CBY21211.1 - 0.06 13.1 0.8 0.9 9.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1834) FGAR-AT_N PF18076.1 CBY21213.1 - 0.017 15.1 0.2 0.025 14.6 0.2 1.3 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Pkinase PF00069.25 CBY21214.1 - 1.5e-28 99.9 1.1 2.3e-28 99.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21214.1 - 1.3e-15 57.4 0.7 1.6e-15 57.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PNISR PF15996.5 CBY21214.1 - 0.011 16.1 10.8 0.017 15.4 10.8 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Endostatin PF06482.11 CBY21214.1 - 0.4 10.1 5.6 0.55 9.6 5.6 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CREPT PF16566.5 CBY21214.1 - 0.41 10.8 11.0 0.84 9.8 11.0 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour LCD1 PF09798.9 CBY21214.1 - 0.77 8.2 9.3 0.87 8.0 9.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein OmpH PF03938.14 CBY21214.1 - 0.85 10.0 10.1 1.5 9.1 10.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.6 CBY21214.1 - 3.3 7.8 9.5 5.5 7.1 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Exonuc_VII_L PF02601.15 CBY21214.1 - 4.6 6.7 8.7 5.2 6.5 8.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 CBY21215.1 - 0.00014 21.3 0.3 0.00021 20.8 0.3 1.4 1 1 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.11 CBY21215.1 - 0.023 13.7 0.6 0.24 10.3 0.1 1.9 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CBY21215.1 - 0.095 11.5 1.0 1.8 7.3 0.1 1.9 1 1 1 2 2 2 0 Fungal protein kinase Aminotran_MocR PF12897.7 CBY21215.1 - 0.18 10.6 0.0 0.2 10.4 0.0 1.0 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Pkinase PF00069.25 CBY21216.1 - 3.7e-24 85.5 0.0 4.2e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21216.1 - 2.1e-06 27.2 0.0 2.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY21216.1 - 0.022 14.1 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like ENTH PF01417.20 CBY21216.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 2 0 0 2 2 2 0 ENTH domain EGF_CA PF07645.15 CBY21218.1 - 1.2e-70 233.5 144.2 2.4e-11 43.6 4.8 11.0 11 0 0 11 11 11 9 Calcium-binding EGF domain cEGF PF12662.7 CBY21218.1 - 7.3e-40 134.5 82.7 4.7e-07 29.6 0.6 11.9 10 3 0 10 10 10 8 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY21218.1 - 1.7e-14 53.7 125.0 4.6e-06 26.7 5.4 11.4 11 1 1 12 12 12 8 EGF domain FXa_inhibition PF14670.6 CBY21218.1 - 3.8e-08 33.5 133.4 8e-05 22.8 11.8 11.0 9 1 0 10 10 10 8 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY21218.1 - 4.5e-06 27.1 115.4 0.00039 20.9 3.6 14.2 14 2 0 14 14 14 5 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY21218.1 - 1.6e-05 24.8 2.7 1.6e-05 24.8 2.7 11.0 11 1 0 11 11 11 3 MSP1 EGF domain 1 EGF PF00008.27 CBY21218.1 - 0.0024 18.1 9.5 0.0024 18.1 9.5 12.6 11 2 2 13 13 13 8 EGF-like domain ATG16 PF08614.11 CBY21219.1 - 0.00075 19.8 7.0 0.0013 19.0 7.0 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 CBY21219.1 - 0.0013 18.9 2.1 0.0013 18.9 2.1 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus GP24_25 PF17388.2 CBY21219.1 - 0.024 14.6 0.6 0.051 13.6 0.6 1.6 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 DNA_photolyase PF00875.18 CBY21219.1 - 0.027 14.5 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 DNA photolyase Mis12 PF05859.12 CBY21219.1 - 0.03 14.4 3.7 0.56 10.3 0.0 2.5 2 0 0 2 2 2 0 Mis12 protein DUF4407 PF14362.6 CBY21219.1 - 0.049 13.0 0.3 0.072 12.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CBY21219.1 - 0.41 8.5 4.4 0.58 8.0 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KIAA1430 PF13879.6 CBY21219.1 - 0.61 10.9 14.3 0.23 12.2 10.6 2.2 2 0 0 2 2 1 0 KIAA1430 homologue betaPIX_CC PF16523.5 CBY21219.1 - 0.95 9.3 12.4 2.7 7.9 9.5 2.5 2 1 0 2 2 2 0 betaPIX coiled coil T3SSipB PF16535.5 CBY21219.1 - 1 9.8 6.9 0.48 10.9 2.6 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB Fungal_TACC PF12709.7 CBY21219.1 - 1.1 9.8 11.5 0.7 10.4 5.5 3.0 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4047 PF13256.6 CBY21219.1 - 1.6 8.9 6.5 3.6 7.8 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF4570 PF15134.6 CBY21219.1 - 2.3 8.3 10.1 8.3 6.5 8.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) DUF1664 PF07889.12 CBY21219.1 - 4.4 7.3 6.1 35 4.5 3.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Glyco_hydro_9 PF00759.19 CBY21220.1 - 3.8e-91 306.6 0.3 5.4e-91 306.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Ldl_recept_a PF00057.18 CBY21220.1 - 7.2e-09 35.7 10.3 7.2e-09 35.7 10.3 1.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A MAM PF00629.23 CBY21220.1 - 1.7e-07 31.3 0.4 5.3e-07 29.7 0.4 1.9 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Mucin PF01456.17 CBY21220.1 - 9.7 6.2 24.4 7.6 6.5 9.6 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein TSP_1 PF00090.19 CBY21221.1 - 2.3e-08 34.1 0.9 4e-08 33.3 0.9 1.4 1 0 0 1 1 1 1 Thrombospondin type 1 domain Kelch_6 PF13964.6 CBY21221.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Kelch motif TSP_1 PF00090.19 CBY21222.1 - 5.6e-74 244.2 231.8 1.2e-08 35.1 9.5 17.5 18 1 0 18 18 18 14 Thrombospondin type 1 domain EGF_CA PF07645.15 CBY21222.1 - 9.3e-10 38.6 8.0 9.3e-10 38.6 8.0 8.4 7 0 0 7 7 7 3 Calcium-binding EGF domain EGF_3 PF12947.7 CBY21222.1 - 2.9e-05 24.1 18.9 0.00011 22.4 7.1 7.4 9 0 0 9 9 9 2 EGF domain EGF PF00008.27 CBY21222.1 - 8.6e-05 22.7 3.5 8.6e-05 22.7 3.5 6.2 5 0 0 5 5 5 1 EGF-like domain cEGF PF12662.7 CBY21222.1 - 0.00036 20.4 1.4 0.00036 20.4 1.4 4.7 4 0 0 4 4 4 1 Complement Clr-like EGF-like hEGF PF12661.7 CBY21222.1 - 0.028 15.1 0.5 0.028 15.1 0.5 6.0 5 0 0 5 5 5 0 Human growth factor-like EGF Lipase PF00151.19 CBY21223.1 - 2.2e-74 250.7 0.0 2.8e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.25 CBY21223.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PAX PF00292.18 CBY21224.1 - 1.8e-40 137.7 0.8 3.9e-40 136.6 0.6 1.6 2 0 0 2 2 2 1 'Paired box' domain Homeodomain PF00046.29 CBY21224.1 - 1.9e-19 69.2 0.5 1.9e-19 69.2 0.5 3.0 4 0 0 4 4 4 1 Homeodomain HTH_23 PF13384.6 CBY21224.1 - 0.00022 20.9 0.1 0.0037 17.0 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain Homeobox_KN PF05920.11 CBY21224.1 - 0.00022 21.0 0.1 0.0006 19.7 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_32 PF13565.6 CBY21224.1 - 0.00032 21.3 1.4 0.0032 18.0 0.0 2.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 CBY21224.1 - 0.0061 16.5 0.2 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix GlgS PF08971.11 CBY21224.1 - 0.058 13.4 0.2 0.18 11.8 0.2 1.8 1 0 0 1 1 1 0 Glycogen synthesis protein PHA_synth_III_E PF09712.10 CBY21224.1 - 0.11 11.6 4.8 0.031 13.4 2.0 1.6 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) SNF PF00209.18 CBY21226.1 - 2.3e-201 670.0 32.5 2.7e-201 669.8 32.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SMN PF06003.12 CBY21227.1 - 9.6e-10 38.1 0.2 9.6e-10 38.1 0.2 2.1 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 CBY21227.1 - 0.00017 21.6 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Tudor domain DUF1325 PF07039.11 CBY21227.1 - 0.0015 18.6 1.1 0.005 16.9 0.0 2.0 2 0 0 2 2 2 1 SGF29 tudor-like domain DUF2368 PF10166.9 CBY21227.1 - 0.048 13.3 1.7 0.11 12.1 1.7 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) SspH PF08141.12 CBY21227.1 - 0.079 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Small acid-soluble spore protein H family Com_YlbF PF06133.11 CBY21227.1 - 5.7 7.6 10.9 0.51 11.0 0.6 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA OLF PF02191.16 CBY21228.1 - 1.6e-83 280.1 5.2 2.4e-83 279.5 5.2 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain tRNA_anti-codon PF01336.25 CBY21229.1 - 4.8e-06 26.5 0.1 7.8e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Bin3 PF06859.12 CBY21230.1 - 1.5e-38 131.7 0.0 3.3e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 CBY21230.1 - 2.9e-13 49.9 0.0 5.1e-09 36.1 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 CBY21230.1 - 7.1e-12 45.9 0.0 2.7e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CBY21230.1 - 5.2e-11 43.2 0.0 1.9e-05 25.3 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CBY21230.1 - 1.2e-10 41.5 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY21230.1 - 4.3e-10 40.1 0.0 7e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain PCMT PF01135.19 CBY21230.1 - 6.3e-06 26.1 0.0 6.4e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CBY21230.1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CBY21230.1 - 3.5e-05 23.8 0.0 7.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY21230.1 - 5.3e-05 22.7 0.0 0.0022 17.4 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CBY21230.1 - 7.9e-05 22.3 0.0 0.0003 20.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Spermine_synth PF01564.17 CBY21230.1 - 0.0009 18.7 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_32 PF13679.6 CBY21230.1 - 0.0016 18.4 0.1 0.004 17.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 CBY21230.1 - 0.0033 16.9 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa CMAS PF02353.20 CBY21230.1 - 0.0073 15.6 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 CBY21230.1 - 0.012 15.1 0.4 0.041 13.3 0.0 2.1 3 0 0 3 3 3 0 Putative methyltransferase UPF0020 PF01170.18 CBY21230.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF43 PF01861.16 CBY21230.1 - 0.061 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain CheR PF01739.18 CBY21230.1 - 0.085 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Pik1 PF11522.8 CBY21230.1 - 0.36 10.8 1.3 0.82 9.7 0.4 2.0 2 0 0 2 2 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 HA2 PF04408.23 CBY21231.1 - 1.7e-19 70.1 0.0 5.5e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY21231.1 - 3.3e-15 56.4 0.0 2.1e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBY21231.1 - 2.1e-07 31.2 0.0 4.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBY21231.1 - 7e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CBY21231.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY21231.1 - 0.00031 21.0 1.0 0.0012 19.2 0.2 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBY21231.1 - 0.0012 19.1 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CBY21231.1 - 0.016 15.8 0.0 0.041 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Herpes_UL37_2 PF07413.11 CBY21231.1 - 0.039 13.2 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 AIG1 PF04548.16 CBY21231.1 - 0.082 12.2 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family ResIII PF04851.15 CBY21231.1 - 0.12 12.3 0.0 0.4 10.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4558 PF15104.6 CBY21232.1 - 0.43 10.7 9.8 0.84 9.7 9.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4558) CLASP_N PF12348.8 CBY21233.1 - 2.4e-08 33.8 0.4 6.4e-08 32.4 0.2 1.7 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 CBY21233.1 - 0.13 12.9 0.2 5.6 7.6 0.0 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region F-box_4 PF15966.5 CBY21234.1 - 1.7e-16 60.2 0.2 4e-16 58.9 0.2 1.6 1 0 0 1 1 1 1 F-box Phospholip_A2_1 PF00068.19 CBY21236.1 - 1.2e-10 41.8 5.1 1.2e-10 41.8 5.1 1.8 2 0 0 2 2 2 1 Phospholipase A2 zf-TRAF_2 PF15965.5 CBY21239.1 - 2.1e-07 31.3 2.2 2.9e-07 30.8 2.2 1.2 1 0 0 1 1 1 1 TRAF-like zinc-finger IL1_propep PF02394.16 CBY21239.1 - 0.011 16.7 0.1 0.016 16.1 0.1 1.5 1 1 0 1 1 1 0 Interleukin-1 propeptide zf-TRAF PF02176.18 CBY21239.1 - 1.5 9.6 8.5 2.6 8.8 7.0 1.9 1 1 1 2 2 2 0 TRAF-type zinc finger fn3 PF00041.21 CBY21240.1 - 8e-92 301.7 63.5 3.1e-06 27.4 0.0 26.5 27 0 0 27 27 27 19 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY21240.1 - 6.2e-12 45.9 33.3 0.019 15.5 0.4 14.0 15 0 0 15 15 15 5 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CBY21240.1 - 0.00023 21.5 24.9 7.7 6.9 0.0 13.1 15 0 0 15 15 15 1 Interferon-alpha/beta receptor, fibronectin type III Aminotran_5 PF00266.19 CBY21240.1 - 0.08 11.9 0.0 2.1 7.2 0.0 2.9 3 0 0 3 3 3 0 Aminotransferase class-V DUF4945 PF16303.5 CBY21240.1 - 5.1 7.0 11.6 3.7 7.5 0.1 5.7 5 1 1 6 6 6 0 Domain of unknown function (DUF4945) PAN_1 PF00024.26 CBY21240.1 - 7.5 6.6 15.6 5 7.2 2.6 2.9 2 1 0 2 2 2 0 PAN domain PKD_channel PF08016.12 CBY21241.1 - 1.4e-43 149.2 5.9 1.4e-43 149.2 5.9 1.8 2 0 0 2 2 2 1 Polycystin cation channel REJ PF02010.15 CBY21241.1 - 2.2e-31 109.2 0.0 5.9e-25 88.0 0.0 2.4 2 0 0 2 2 2 2 REJ domain PLAT PF01477.23 CBY21241.1 - 3.9e-16 59.7 0.2 2.4e-14 53.9 0.0 2.9 2 0 0 2 2 2 1 PLAT/LH2 domain GPS PF01825.21 CBY21241.1 - 4.9e-05 23.8 0.9 0.00012 22.6 0.9 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif GPHR_N PF12537.8 CBY21241.1 - 0.14 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal Ion_trans PF00520.31 CBY21242.1 - 0.0071 15.6 1.6 0.012 14.9 1.6 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CBY21242.1 - 0.0081 14.9 2.2 0.013 14.2 2.2 1.3 1 0 0 1 1 1 1 Polycystin cation channel CBM_14 PF01607.24 CBY21243.1 - 1.6e-10 41.0 2.8 1.6e-10 41.0 2.8 4.9 4 1 0 4 4 4 1 Chitin binding Peritrophin-A domain Serglycin PF04360.12 CBY21243.1 - 0.003 17.5 9.7 0.056 13.4 0.5 2.7 2 0 0 2 2 2 2 Serglycin GABP-alpha PF11620.8 CBY21244.1 - 0.14 12.4 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 GA-binding protein alpha chain GYF_2 PF14237.6 CBY21245.1 - 1.7e-13 50.1 0.4 4.7e-13 48.7 0.2 2.0 2 0 0 2 2 2 1 GYF domain 2 DnaJ PF00226.31 CBY21245.1 - 2.1e-06 27.8 0.0 4.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Arm PF00514.23 CBY21245.1 - 5.2e-05 23.1 7.1 0.022 14.8 0.3 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Sec3-PIP2_bind PF15277.6 CBY21245.1 - 0.00052 20.1 1.5 0.082 13.0 0.4 2.9 3 0 0 3 3 3 2 Exocyst complex component SEC3 N-terminal PIP2 binding PH KIAA1430 PF13879.6 CBY21245.1 - 0.37 11.6 2.4 0.84 10.4 0.1 2.5 2 0 0 2 2 2 0 KIAA1430 homologue HECT PF00632.25 CBY21246.1 - 2e-78 264.0 0.0 3.5e-78 263.2 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT_2 PF13646.6 CBY21246.1 - 0.0016 18.8 3.5 0.16 12.4 0.1 4.4 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CBY21246.1 - 0.036 14.3 5.2 5.6 7.5 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 CBY21246.1 - 0.072 13.6 1.9 11 6.7 0.0 4.0 3 1 1 4 4 4 0 HEAT-like repeat RIH_assoc PF08454.11 CBY21246.1 - 0.08 12.8 7.0 1.7 8.6 0.4 3.5 3 0 0 3 3 3 0 RyR and IP3R Homology associated CLASP_N PF12348.8 CBY21246.1 - 0.25 10.9 2.9 2.4 7.7 0.2 2.8 3 0 0 3 3 3 0 CLASP N terminal Arm PF00514.23 CBY21246.1 - 0.33 11.1 0.0 0.33 11.1 0.0 3.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ndc1_Nup PF09531.10 CBY21246.1 - 5.3 5.6 15.6 0.049 12.3 3.8 2.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup PX PF00787.24 CBY21247.1 - 2.3e-05 24.3 0.2 4.1e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 PX domain PDZ PF00595.24 CBY21248.1 - 3.8e-09 36.8 0.4 1.2e-08 35.2 0.4 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY21248.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Diacid_rec PF05651.13 CBY21248.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative sugar diacid recognition Pkinase_Tyr PF07714.17 CBY21249.1 - 1.1e-74 251.1 0.0 1.1e-73 247.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY21249.1 - 6e-31 107.8 0.1 3.6e-30 105.2 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY21249.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 CBY21249.1 - 0.056 12.4 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Sld5 PF05916.11 CBY21250.1 - 5.5e-05 23.6 0.1 9.8e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 CBY21250.1 - 0.044 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus DUF3879 PF12995.7 CBY21250.1 - 0.096 12.4 0.0 4.4 7.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) SF3b10 PF07189.11 CBY21251.1 - 5.6e-37 125.7 0.0 6.3e-37 125.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Peptidase_S9_N PF02897.15 CBY21252.1 - 1.7e-106 356.5 0.1 2.3e-106 356.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CBY21252.1 - 1.5e-58 197.8 0.0 2.7e-58 196.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CBY21252.1 - 0.11 12.4 0.1 0.47 10.3 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CBY21252.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CBY21252.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CENP-C_C PF11699.8 CBY21253.1 - 0.01 16.1 0.2 0.025 14.8 0.2 1.7 1 0 0 1 1 1 0 Mif2/CENP-C like AT_hook PF02178.19 CBY21253.1 - 0.074 13.0 4.1 0.42 10.6 4.1 2.5 1 0 0 1 1 1 0 AT hook motif Cluap1 PF10234.9 CBY21254.1 - 0.23 10.8 1.8 0.26 10.7 1.8 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Pannexin_like PF12534.8 CBY21254.1 - 1.6 7.7 3.1 2 7.4 3.1 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Herpes_pp85 PF04637.12 CBY21255.1 - 8.2 4.7 8.1 9.2 4.5 8.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) p450 PF00067.22 CBY21256.1 - 2e-24 86.2 0.0 2.3e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CBY21257.1 - 8e-11 41.3 0.2 1e-10 41.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 SLC3A2_N PF16028.5 CBY21257.1 - 0.15 11.6 0.9 2.3 7.8 0.0 2.5 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus PDZ PF00595.24 CBY21259.1 - 7.2e-21 74.3 0.0 6.8e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY21259.1 - 2e-16 59.6 0.1 1e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY21259.1 - 5.1e-05 23.5 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CBY21259.1 - 0.011 15.6 0.0 0.95 9.5 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain Ion_trans PF00520.31 CBY21260.1 - 4.6e-16 58.8 30.3 4.3e-08 32.7 19.7 2.3 2 0 0 2 2 2 2 Ion transport protein PMT_4TMC PF16192.5 CBY21260.1 - 0.42 10.2 12.1 2 7.9 0.1 3.7 4 0 0 4 4 4 0 C-terminal four TMM region of protein-O-mannosyltransferase DUF456 PF04306.13 CBY21260.1 - 3.6 7.9 0.0 3.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF456) Sulfotransfer_2 PF03567.14 CBY21263.1 - 2e-06 27.9 0.0 2.1e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family PSD4 PF07631.11 CBY21263.1 - 0.031 14.8 0.0 0.045 14.3 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1592) DUF2451 PF10474.9 CBY21263.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Sulfotransfer_2 PF03567.14 CBY21264.1 - 2.4e-09 37.5 0.2 4.3e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Sulfotransferase family Asparaginase PF00710.20 CBY21264.1 - 0.29 10.6 0.5 11 5.6 0.0 2.3 2 1 1 3 3 3 0 Asparaginase, N-terminal DnaJ PF00226.31 CBY21265.1 - 3.7e-25 87.8 0.3 1e-12 48.0 0.1 2.3 2 0 0 2 2 2 2 DnaJ domain Phage_TAC_3 PF06896.11 CBY21265.1 - 0.093 13.3 0.1 0.34 11.5 0.1 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, TAC DnaJ PF00226.31 CBY21266.1 - 5.3e-11 42.5 0.4 5.3e-11 42.5 0.4 2.2 2 0 0 2 2 2 1 DnaJ domain HORMA PF02301.18 CBY21266.1 - 0.021 14.4 0.1 0.046 13.3 0.1 1.5 1 0 0 1 1 1 0 HORMA domain Annexin PF00191.20 CBY21266.1 - 0.092 12.8 0.5 0.24 11.5 0.5 1.7 1 0 0 1 1 1 0 Annexin EGF PF00008.27 CBY21268.1 - 3.1e-06 27.4 8.7 8.2e-06 26.0 6.5 2.0 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 CBY21268.1 - 0.00044 20.8 3.3 0.00044 20.8 3.3 2.7 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_CA PF07645.15 CBY21268.1 - 0.0021 18.2 2.8 0.0021 18.2 2.8 1.9 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY21268.1 - 0.014 15.5 9.9 0.077 13.2 7.5 2.3 1 1 1 2 2 2 0 EGF domain MDH PF02315.16 CBY21268.1 - 0.45 10.6 3.3 18 5.5 3.3 2.0 1 1 0 1 1 1 0 Methanol dehydrogenase beta subunit Ig_3 PF13927.6 CBY21269.1 - 2.5e-19 69.7 0.2 4.4e-05 24.0 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CBY21269.1 - 1e-14 54.4 1.0 0.00013 22.0 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY21269.1 - 2.5e-14 53.3 1.1 0.0001 22.6 0.0 4.1 3 2 1 4 4 4 3 Immunoglobulin domain ig PF00047.25 CBY21269.1 - 2.6e-10 40.3 1.2 0.082 13.1 0.0 4.1 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 CBY21269.1 - 4.4e-09 36.5 0.4 0.003 17.7 0.0 4.0 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_4 PF16680.5 CBY21269.1 - 1.2e-07 31.9 0.7 0.011 15.9 0.0 3.1 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CBY21269.1 - 1e-06 29.0 1.0 0.22 12.0 0.2 3.6 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 CBY21269.1 - 0.00055 19.4 0.0 0.033 13.8 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain C2-set PF05790.15 CBY21269.1 - 0.0096 16.1 0.1 10 6.4 0.0 3.7 2 1 2 4 4 4 1 Immunoglobulin C2-set domain Protocadherin PF08374.11 CBY21269.1 - 0.012 15.6 0.1 0.027 14.5 0.1 1.5 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.6 CBY21269.1 - 0.031 15.2 0.0 0.07 14.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Izumo-Ig PF16706.5 CBY21269.1 - 0.087 12.9 0.0 5.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Lectin_C PF00059.21 CBY21270.1 - 3.2e-11 43.9 0.1 1.5e-10 41.8 0.0 2.2 3 0 0 3 3 3 1 Lectin C-type domain NPV_P10 PF05531.12 CBY21270.1 - 0.022 15.2 4.6 2.4 8.7 0.7 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.14 CBY21270.1 - 3.4 7.4 5.2 16 5.2 1.3 2.5 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Ifi-6-16 PF06140.13 CBY21271.1 - 6e-07 29.3 10.5 2.2e-06 27.5 10.4 1.9 1 1 0 1 1 1 1 Interferon-induced 6-16 family TMEM40 PF15817.5 CBY21271.1 - 0.13 12.1 1.3 0.19 11.5 1.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 40 family ECF_trnsprt PF12822.7 CBY21271.1 - 0.34 11.0 8.7 0.43 10.6 8.7 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Tetraspanin PF00335.20 CBY21272.1 - 0.012 15.4 0.2 0.014 15.1 0.2 1.1 1 0 0 1 1 1 0 Tetraspanin family Metallophos PF00149.28 CBY21274.1 - 3.7e-15 57.0 0.2 5.3e-15 56.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 CBY21274.1 - 0.01 14.9 0.1 0.43 9.5 0.1 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase Metallophos_2 PF12850.7 CBY21274.1 - 0.066 13.4 0.5 0.54 10.4 0.5 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Cornifin PF02389.15 CBY21275.1 - 0.64 10.2 47.4 7.1 6.8 47.4 2.0 1 1 0 1 1 1 0 Cornifin (SPRR) family Arf PF00025.21 CBY21276.1 - 1.1e-58 197.6 0.0 1.4e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBY21276.1 - 1.8e-15 56.9 0.0 2.3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY21276.1 - 3.2e-15 56.4 0.0 4.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CBY21276.1 - 2.4e-14 53.3 1.1 5.1e-08 32.5 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY21276.1 - 1.5e-10 40.8 0.0 2.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY21276.1 - 3.9e-10 39.5 0.0 5.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 CBY21276.1 - 8.8e-05 21.9 0.2 0.00015 21.1 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 CBY21276.1 - 0.0039 17.3 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 CBY21276.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NTPase Clat_adaptor_s PF01217.20 CBY21277.1 - 1.4e-53 180.7 2.4 1.7e-53 180.4 2.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3919 PF13057.6 CBY21277.1 - 0.043 13.4 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Clat_adaptor_s PF01217.20 CBY21278.1 - 6e-38 130.0 1.0 7.3e-38 129.7 1.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Metallophos PF00149.28 CBY21280.1 - 1.3e-30 107.4 0.2 1.9e-30 106.9 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CBY21280.1 - 7.5e-24 83.8 1.6 1.5e-23 82.9 0.9 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 CBY21280.1 - 2.7e-17 61.8 3.6 2.9e-05 23.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY21280.1 - 1e-14 53.3 3.4 0.0015 18.5 0.0 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBY21280.1 - 9.3e-13 47.6 0.5 0.00014 21.5 0.1 3.5 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 CBY21280.1 - 8.7e-10 38.0 2.7 0.02 15.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBY21280.1 - 1.4e-06 28.4 0.0 3.1e-05 24.0 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY21280.1 - 3.3e-06 27.1 0.1 0.14 12.6 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY21280.1 - 6.3e-06 26.6 0.1 0.0044 17.5 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY21280.1 - 2.6e-05 24.8 1.9 0.0089 16.7 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY21280.1 - 9.1e-05 22.7 0.1 0.029 14.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY21280.1 - 0.00019 22.0 0.1 0.23 12.4 0.0 3.3 2 1 2 4 4 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBY21280.1 - 0.012 15.0 0.2 28 4.3 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR TPR_6 PF13174.6 CBY21280.1 - 0.022 15.4 0.6 5.6 7.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 CBY21280.1 - 0.066 12.4 0.1 1.7 7.8 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY21280.1 - 0.15 12.1 0.0 12 6.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBY21280.1 - 0.28 11.6 1.0 19 5.7 0.1 2.6 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation MIT PF04212.18 CBY21280.1 - 0.65 10.1 3.7 0.66 10.1 0.3 2.6 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain N_Asn_amidohyd PF14736.6 CBY21281.1 - 1.8e-98 329.0 0.0 2.2e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase PNP_UDP_1 PF01048.20 CBY21282.1 - 7.3e-37 126.9 0.0 8.2e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily 2OG-FeII_Oxy_3 PF13640.6 CBY21283.1 - 9.6e-06 26.4 0.0 1.9e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 CBY21283.1 - 0.0017 18.3 6.7 0.0076 16.3 1.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY21283.1 - 0.053 13.4 2.1 7.2 6.6 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY21283.1 - 0.11 12.6 1.6 1 9.5 0.1 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3724 PF12521.8 CBY21283.1 - 2 8.5 3.7 1.3 9.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) DUF913 PF06025.12 CBY21284.1 - 6.9e-102 341.2 2.3 6.9e-102 341.2 2.3 8.1 8 1 0 8 8 8 2 Domain of Unknown Function (DUF913) HECT PF00632.25 CBY21284.1 - 4.4e-92 308.8 1.2 8.4e-92 307.9 1.2 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 CBY21284.1 - 1.1e-23 84.2 5.0 7.1e-14 52.0 0.2 7.0 7 1 1 8 8 8 2 Domain of Unknown Function (DUF908) UBM PF14377.6 CBY21284.1 - 8.3e-17 60.0 13.0 1.8e-06 27.1 0.1 4.6 3 1 1 4 4 4 3 Ubiquitin binding region WWE PF02825.20 CBY21284.1 - 1e-07 32.4 1.4 4e-07 30.5 1.4 2.2 1 0 0 1 1 1 1 WWE domain UBA PF00627.31 CBY21284.1 - 8.6e-05 22.4 0.3 0.00023 21.0 0.3 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UIM PF02809.20 CBY21284.1 - 0.053 13.5 1.3 0.21 11.6 1.3 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif RICTOR_M PF14666.6 CBY21284.1 - 0.12 12.1 0.8 3.2 7.6 0.1 3.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Methyltransf_25 PF13649.6 CBY21285.1 - 3.7e-07 30.7 0.0 1.3e-06 29.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY21285.1 - 6.5e-07 29.3 0.1 2.3e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY21285.1 - 0.012 16.3 0.1 0.056 14.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 CBY21285.1 - 0.094 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ig_3 PF13927.6 CBY21286.1 - 9.8e-35 119.0 4.1 3.1e-08 34.1 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 CBY21286.1 - 1.4e-25 89.2 3.5 3.5e-08 33.4 0.0 6.4 5 3 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY21286.1 - 5.7e-25 87.5 0.0 0.00016 22.0 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 CBY21286.1 - 1.1e-16 60.9 0.4 7.6e-10 38.9 0.0 5.7 5 1 1 6 6 6 2 Immunoglobulin V-set domain ig PF00047.25 CBY21286.1 - 4.3e-16 58.8 1.7 0.00024 21.2 0.0 6.2 5 2 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY21286.1 - 5.3e-10 39.2 3.3 3.4e-06 27.0 0.0 4.4 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 CBY21286.1 - 0.0043 17.1 0.1 1.6 8.8 0.1 3.5 4 1 0 4 4 4 1 C17orf99 Ig domain OS-D PF03392.13 CBY21287.1 - 0.14 12.2 0.1 0.92 9.7 0.0 2.0 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Peripla_BP_2 PF01497.18 CBY21287.1 - 0.15 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein RRM_1 PF00076.22 CBY21289.1 - 0.01 15.6 0.0 1.8 8.4 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CBY21290.1 - 1.5e-51 175.3 0.0 9e-51 172.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21290.1 - 3.2e-35 121.7 0.0 4.7e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY21290.1 - 1.7e-06 27.1 0.0 2.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY21290.1 - 0.00074 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY21290.1 - 0.0012 18.3 0.1 0.0035 16.7 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CBY21290.1 - 0.0066 15.4 0.5 0.016 14.2 0.5 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Peptidase_S30 PF01577.16 CBY21290.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease FTA2 PF13095.6 CBY21290.1 - 0.026 14.2 0.0 0.062 12.9 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBY21290.1 - 0.24 11.3 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family V-set PF07686.17 CBY21291.1 - 0.00086 19.5 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain DUF2385 PF09539.10 CBY21291.1 - 0.064 13.8 0.1 4.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Ank_2 PF12796.7 CBY21293.1 - 4.4e-33 113.7 0.0 4.2e-12 46.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY21293.1 - 2.4e-28 97.8 1.3 1.5e-08 34.7 0.1 4.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY21293.1 - 3.7e-26 88.3 0.1 2.7e-06 27.3 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 CBY21293.1 - 3.7e-24 84.1 0.7 2.4e-05 24.6 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 CBY21293.1 - 2.1e-23 82.4 0.5 5.2e-06 26.9 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Pur_ac_phosph_N PF16656.5 CBY21293.1 - 0.061 13.9 0.1 0.15 12.6 0.1 1.6 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 CBY21293.1 - 0.19 11.9 0.2 0.93 9.7 0.2 2.2 1 1 0 1 1 1 0 Fibronectin type III domain FAM195 PF14799.6 CBY21294.1 - 9.9e-08 32.3 4.1 1.3e-07 31.9 4.1 1.2 1 0 0 1 1 1 1 FAM195 family BDHCT_assoc PF16204.5 CBY21294.1 - 0.063 13.0 7.6 0.21 11.3 0.9 2.7 1 1 2 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein Ion_trans PF00520.31 CBY21295.1 - 1.9e-50 171.4 13.7 2.5e-50 171.0 13.7 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CBY21295.1 - 7.7e-19 67.9 0.0 2.6e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CBY21295.1 - 2.9e-12 46.4 8.6 3.1e-12 46.3 5.4 2.4 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 CBY21295.1 - 0.00061 18.6 2.2 0.00061 18.6 2.2 2.0 1 1 1 2 2 2 1 Polycystin cation channel Sld5 PF05916.11 CBY21295.1 - 0.031 14.7 0.0 0.078 13.5 0.0 1.6 1 0 0 1 1 1 0 GINS complex protein WAK PF08488.11 CBY21295.1 - 0.12 12.9 0.1 0.24 12.0 0.1 1.4 1 0 0 1 1 1 0 Wall-associated kinase Sigma_reg_N PF13800.6 CBY21295.1 - 1.8 8.9 4.5 3.9 7.8 0.1 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal zf-B_box PF00643.24 CBY21296.1 - 4.7e-11 42.6 39.6 4.4e-10 39.5 8.8 4.4 4 0 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 CBY21296.1 - 3.6e-05 23.7 1.0 3.6e-05 23.7 1.0 3.8 3 2 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY21296.1 - 5.2e-05 23.5 4.6 5.2e-05 23.5 4.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CBY21296.1 - 8.7e-05 22.4 8.4 8.7e-05 22.4 8.4 3.8 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY21296.1 - 0.0021 17.9 4.3 0.0021 17.9 4.3 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY21296.1 - 0.037 14.2 1.4 0.037 14.2 1.4 4.2 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING SUIM_assoc PF16619.5 CBY21296.1 - 9.9 6.3 9.8 20 5.3 2.4 3.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 efThoc1 PF11957.8 CBY21297.1 - 3.1e-126 421.9 18.8 3.1e-126 421.9 18.8 1.5 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 CBY21297.1 - 1.2e-10 41.4 0.3 3.7e-10 39.8 0.3 1.9 1 0 0 1 1 1 1 Death domain DUF2130 PF09903.9 CBY21297.1 - 0.0022 17.3 1.4 0.0022 17.3 1.4 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2130) DUF2408 PF10303.9 CBY21297.1 - 0.35 11.4 4.3 4.8 7.7 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) FoP_duplication PF13865.6 CBY21298.1 - 1.8e-23 82.9 35.8 7.8e-17 61.6 19.9 4.6 2 2 1 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 Radical_SAM PF04055.21 CBY21299.1 - 2.2e-21 76.9 1.7 4.6e-21 75.9 0.3 2.4 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 CBY21299.1 - 1.5e-17 63.4 0.1 1.1e-16 60.7 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 UPF0242 PF06785.11 CBY21299.1 - 0.0031 17.7 6.1 0.0031 17.7 6.1 10.2 1 1 8 9 9 9 1 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 CBY21299.1 - 0.0067 16.6 7.2 0.0067 16.6 7.2 10.3 3 2 8 11 11 11 2 Fibrinogen alpha/beta chain family TRAM PF01938.20 CBY21299.1 - 0.0089 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Nic96 PF04097.14 CBY21300.1 - 1.5e-169 565.4 0.0 1.8e-169 565.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 RAMP4 PF06624.12 CBY21300.1 - 9.5e-24 83.2 0.1 2.1e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Clathrin PF00637.20 CBY21300.1 - 0.032 14.1 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Peptidase_M16_M PF16187.5 CBY21300.1 - 0.04 13.2 0.1 0.096 12.0 0.1 1.5 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 ANAPC3 PF12895.7 CBY21300.1 - 0.069 13.4 1.1 0.42 10.9 0.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Comm PF15957.5 CBY21301.1 - 0.013 15.9 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 0 Commissureless RCR PF12273.8 CBY21301.1 - 0.039 14.6 0.0 0.063 13.9 0.0 1.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Mucin PF01456.17 CBY21301.1 - 0.057 13.4 1.6 0.072 13.1 1.6 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF1899 PF08953.11 CBY21302.1 - 3.2e-30 103.8 0.0 7.9e-30 102.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CBY21302.1 - 2.8e-22 78.3 0.1 4.8e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CBY21302.1 - 1.2e-11 44.9 4.0 3.2e-06 27.8 0.6 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21302.1 - 3.8e-10 39.9 0.7 0.06 13.7 0.0 4.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Trimer_CC PF08954.11 CBY21302.1 - 0.0039 16.7 1.9 0.0078 15.7 1.1 1.9 2 0 0 2 2 2 1 Trimerisation motif WHAMM-JMY_N PF15920.5 CBY21302.1 - 0.035 14.0 0.2 0.6 10.0 0.0 2.3 1 1 1 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated PB1 PF00564.24 CBY21303.1 - 1.7e-08 34.3 0.1 2.8e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 CBY21303.1 - 4.8e-08 33.2 0.1 7.9e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY21303.1 - 8.8e-06 25.5 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Rad60-SLD PF11976.8 CBY21304.1 - 8.3e-06 25.5 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY21304.1 - 0.038 13.7 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family SMN PF06003.12 CBY21305.1 - 3.9e-11 42.7 7.7 2.1e-07 30.5 1.7 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) YL1 PF05764.13 CBY21305.1 - 0.012 15.8 1.1 0.014 15.5 1.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF4537 PF15057.6 CBY21305.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF4094 PF13334.6 CBY21306.1 - 0.83 10.1 4.3 12 6.4 4.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Hydrolase_4 PF12146.8 CBY21307.1 - 1e-45 155.9 0.0 1.2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY21307.1 - 1.6e-17 64.0 0.2 8.1e-11 42.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY21307.1 - 1.2e-12 48.9 0.0 1.5e-12 48.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CBY21307.1 - 2e-06 27.7 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 CBY21307.1 - 5.6e-06 26.4 0.0 2.3e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Peptidase_S28 PF05577.12 CBY21307.1 - 6.5e-06 25.2 0.0 8.9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DLH PF01738.18 CBY21307.1 - 3.2e-05 23.6 0.0 0.031 13.8 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CBY21307.1 - 3.3e-05 23.5 0.0 0.037 13.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PGAP1 PF07819.13 CBY21307.1 - 0.00047 19.9 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 CBY21307.1 - 0.00062 19.6 0.0 0.0061 16.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CBY21307.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 CBY21307.1 - 0.002 18.0 0.0 0.0066 16.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CBY21307.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase Cutinase PF01083.22 CBY21307.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 2 0 0 2 2 1 0 Cutinase DUF900 PF05990.12 CBY21307.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.20 CBY21307.1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 CBY21307.1 - 0.029 14.3 0.0 4.2 7.2 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1057 PF06342.12 CBY21307.1 - 0.033 13.2 0.0 0.086 11.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2920 PF11144.8 CBY21307.1 - 0.068 12.3 0.0 0.083 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2920) Palm_thioest PF02089.15 CBY21307.1 - 0.11 12.3 0.0 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Acetyltransf_15 PF17013.5 CBY21307.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase EF-hand_6 PF13405.6 CBY21308.1 - 2.5e-15 55.0 12.1 0.0016 18.2 0.0 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 CBY21308.1 - 1.4e-14 52.4 17.7 9.9e-06 24.8 0.3 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBY21308.1 - 1.7e-14 54.0 9.0 1.5e-09 38.2 1.6 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY21308.1 - 0.00012 21.4 17.9 0.17 11.5 1.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 CBY21308.1 - 0.0036 17.1 12.5 0.54 10.2 0.3 3.8 2 2 2 4 4 4 2 EF-hand domain pair Headcase PF16002.5 CBY21309.1 - 3.3e-75 251.9 9.8 5e-75 251.3 9.8 1.2 1 0 0 1 1 1 1 Headcase protein HECA PF15353.6 CBY21309.1 - 8.1e-19 67.8 1.0 8.1e-19 67.8 1.0 2.2 3 0 0 3 3 3 1 Headcase protein family homologue Rhodanese_C PF12368.8 CBY21309.1 - 0.0015 18.9 0.3 0.0015 18.9 0.3 4.5 4 1 2 6 6 6 1 Rhodanase C-terminal RVT_1 PF00078.27 CBY21310.1 - 0.0022 17.6 0.0 0.0052 16.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CBY21310.1 - 0.0062 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CBY21310.1 - 0.012 15.4 0.0 0.056 13.3 0.0 2.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase fn3 PF00041.21 CBY21312.1 - 3.4e-33 113.9 14.0 0.00023 21.4 0.3 8.8 8 1 0 8 8 8 7 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY21312.1 - 4.1e-05 24.1 11.9 2.1 9.0 0.1 7.5 5 2 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Activin_recp PF01064.23 CBY21312.1 - 0.03 15.4 17.9 0.05 14.7 17.9 1.3 1 0 0 1 1 1 0 Activin types I and II receptor domain DUF2369 PF10179.9 CBY21312.1 - 0.046 14.1 1.9 64 4.0 0.0 5.1 6 1 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) Toxin_TOLIP PF00087.21 CBY21312.1 - 2.1 8.7 16.8 3.9 7.8 16.8 1.5 1 0 0 1 1 1 0 Snake toxin and toxin-like protein BAMBI PF06211.12 CBY21312.1 - 2.4 8.4 8.3 5 7.4 8.3 1.5 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain BTB PF00651.31 CBY21313.1 - 1.3e-21 76.9 0.0 3.1e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain GAD-like PF08887.11 CBY21313.1 - 0.081 12.7 0.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 GAD-like domain Adeno_PV PF03910.13 CBY21313.1 - 0.082 11.6 1.0 7.7 5.1 0.1 2.4 2 0 0 2 2 2 0 Adenovirus minor core protein PV Trypsin PF00089.26 CBY21314.1 - 1.2e-56 192.0 0.1 2.1e-56 191.2 0.1 1.4 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 CBY21314.1 - 4.3e-26 91.4 3.4 1.4e-13 51.1 0.2 3.6 3 0 0 3 3 3 3 CUB domain Trypsin_2 PF13365.6 CBY21314.1 - 4.3e-05 24.5 0.0 9.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Collagen PF01391.18 CBY21315.1 - 3.4e-83 273.3 342.9 6e-10 38.7 24.6 12.1 2 2 7 9 9 9 7 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CBY21315.1 - 3.7e-62 209.7 0.1 5.2e-62 209.2 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Collagen PF01391.18 CBY21316.1 - 1.8e-50 168.5 202.2 1.7e-10 40.5 26.9 7.3 1 1 5 6 6 6 6 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 CBY21316.1 - 0.13 12.9 0.0 0.2 12.3 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Sulfotransfer_2 PF03567.14 CBY21317.1 - 0.0088 16.0 4.5 0.11 12.4 4.4 2.2 1 1 0 1 1 1 1 Sulfotransferase family HLH PF00010.26 CBY21318.1 - 1.6e-06 28.0 0.3 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Sec66 PF09802.9 CBY21318.1 - 0.029 13.9 0.4 0.058 13.0 0.4 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 CagA PF03507.13 CBY21318.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 CagA exotoxin AAA_6 PF12774.7 CBY21319.1 - 8.4e-16 57.8 0.1 1.2e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region LMBR1 PF04791.16 CBY21320.1 - 1.4 7.7 9.7 1.6 7.5 9.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PI3_PI4_kinase PF00454.27 CBY21321.1 - 5.1e-31 108.4 0.7 9.5e-26 91.1 0.6 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase C2 PF00168.30 CBY21321.1 - 3.5e-10 40.1 0.0 6.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF4135 PF13575.6 CBY21321.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Peptidase_C92 PF05708.12 CBY21321.1 - 0.14 12.2 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Phospholip_A2_1 PF00068.19 CBY21322.1 - 1.8e-17 63.8 8.2 7.8e-17 61.8 8.2 1.9 1 1 0 1 1 1 1 Phospholipase A2 DUF3902 PF13042.6 CBY21323.1 - 0.32 10.6 6.9 0.41 10.2 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) Cadherin PF00028.17 CBY21324.1 - 1.2e-119 391.0 15.6 4e-21 75.3 0.0 8.1 8 0 0 8 8 8 6 Cadherin domain 7tm_2 PF00002.24 CBY21324.1 - 2.6e-25 89.1 10.1 4.8e-25 88.3 10.1 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_2 PF02210.24 CBY21324.1 - 1e-23 84.3 0.6 4.8e-14 53.0 0.1 2.7 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 CBY21324.1 - 1e-17 64.5 0.5 1.2e-10 41.7 0.0 3.2 3 0 0 3 3 2 2 Laminin G domain EGF PF00008.27 CBY21324.1 - 9.1e-15 54.6 91.7 2.8e-06 27.5 6.6 8.4 8 0 0 8 8 7 5 EGF-like domain GPS PF01825.21 CBY21324.1 - 2.6e-12 47.1 3.1 2.6e-12 47.1 3.1 3.6 3 0 0 3 3 1 1 GPCR proteolysis site, GPS, motif Cadherin_2 PF08266.12 CBY21324.1 - 1.6e-08 34.3 1.1 0.77 9.6 0.0 7.0 7 0 0 7 7 7 2 Cadherin-like Laminin_EGF PF00053.24 CBY21324.1 - 2e-07 31.0 14.1 2e-07 31.0 14.1 8.3 6 2 2 8 8 7 2 Laminin EGF domain Cadherin_3 PF16184.5 CBY21324.1 - 1.5e-05 24.9 18.4 1.4 9.0 0.1 7.1 8 0 0 8 8 8 3 Cadherin-like RET_CLD1 PF17756.1 CBY21324.1 - 0.00061 20.1 0.0 1.7 9.0 0.0 5.1 6 0 0 6 6 5 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 CBY21324.1 - 0.0025 18.4 30.0 0.034 14.8 0.6 7.0 6 0 0 6 6 6 1 Bacterial cadherin-like domain EGF_2 PF07974.13 CBY21324.1 - 0.0054 17.1 10.2 0.0054 17.1 10.2 9.5 8 2 1 9 9 6 4 EGF-like domain hEGF PF12661.7 CBY21324.1 - 0.0068 17.0 6.7 0.0068 17.0 6.7 8.5 9 0 0 9 9 6 3 Human growth factor-like EGF Laminin_G_3 PF13385.6 CBY21324.1 - 0.011 15.9 0.1 0.18 11.9 0.0 2.9 3 0 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily PsbP PF01789.16 CBY21324.1 - 0.31 11.2 2.3 1.1 9.3 0.1 2.9 3 0 0 3 3 3 0 PsbP Big_9 PF17963.1 CBY21324.1 - 2 9.2 22.0 1.5 9.6 0.2 6.6 7 0 0 7 7 6 0 Bacterial Ig domain YpmT PF17431.2 CBY21324.1 - 3.5 7.7 6.0 1.5 8.9 1.0 2.5 2 0 0 2 2 2 0 Uncharacterized YmpT-like Phospholip_A2_1 PF00068.19 CBY21325.1 - 2e-14 54.0 2.5 2e-14 54.0 2.5 2.1 2 0 0 2 2 2 1 Phospholipase A2 VbhA PF18495.1 CBY21325.1 - 0.23 11.3 0.2 0.48 10.3 0.2 1.4 1 0 0 1 1 1 0 Antitoxin VbhA zf-H2C2_2 PF13465.6 CBY21328.1 - 1.2e-11 44.4 11.9 5.2e-07 29.8 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY21328.1 - 1.5e-10 40.9 11.3 5.2e-06 26.6 1.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY21328.1 - 3.2e-09 36.8 8.6 6.1e-05 23.5 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CBY21328.1 - 1.2e-06 28.7 2.6 0.00029 21.1 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY21328.1 - 3.7e-05 23.9 1.6 0.00092 19.4 0.0 2.8 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY21328.1 - 0.0077 16.5 1.9 2 8.8 0.1 2.6 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 CBY21328.1 - 0.038 13.9 0.5 0.099 12.5 0.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_6 PF13912.6 CBY21328.1 - 0.054 13.5 0.7 0.054 13.5 0.7 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CCHC_2 PF13696.6 CBY21328.1 - 0.056 13.3 6.9 1.7 8.5 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-BED PF02892.15 CBY21328.1 - 0.18 11.9 6.1 3.2 7.8 1.1 2.6 2 1 1 3 3 2 0 BED zinc finger zf-C2HC_2 PF13913.6 CBY21328.1 - 0.2 11.6 2.6 4.3 7.4 0.8 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Vps39_2 PF10367.9 CBY21328.1 - 0.26 11.7 1.6 1 9.8 0.4 2.4 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Zf_RING PF16744.5 CBY21328.1 - 0.57 10.3 4.0 3.8 7.7 0.4 2.6 2 1 0 3 3 3 0 KIAA1045 RING finger Methyltransf_13 PF08421.11 CBY21328.1 - 0.77 10.0 3.5 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 Putative zinc binding domain WBP-1 PF11669.8 CBY21329.1 - 0.0005 20.7 1.8 0.014 16.0 0.1 2.2 2 0 0 2 2 2 1 WW domain-binding protein 1 DUF973 PF06157.11 CBY21329.1 - 0.028 13.5 0.8 0.04 13.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) ETRAMP PF09716.10 CBY21329.1 - 9.1 6.4 9.2 78 3.4 9.2 2.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PA28_beta PF02252.18 CBY21330.1 - 1.2e-48 164.5 3.3 2.1e-48 163.7 3.3 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 CBY21330.1 - 0.00024 21.0 0.1 0.00082 19.4 0.1 1.9 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Mon2_C PF16206.5 CBY21331.1 - 4.1e-87 293.1 11.2 2.5e-60 204.6 0.2 3.1 1 1 1 2 2 2 2 C-terminal region of Mon2 protein Sec7_N PF12783.7 CBY21331.1 - 1.1e-30 106.7 1.8 1.1e-30 106.7 1.8 4.4 5 1 1 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CBY21331.1 - 2.9e-25 88.9 2.4 2.9e-25 88.9 2.4 3.4 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 CBY21331.1 - 6.1e-16 58.1 2.6 5.1e-14 51.9 0.2 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) PIH1_CS PF18201.1 CBY21332.1 - 1.7e-09 38.0 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain CARD PF00619.21 CBY21332.1 - 0.046 13.8 1.5 6.5 6.9 0.0 3.3 3 0 0 3 3 3 0 Caspase recruitment domain DUF908 PF06012.12 CBY21332.1 - 1.3 8.3 6.1 3.8 6.8 6.0 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) DNA_pol3_delta2 PF13177.6 CBY21333.1 - 2e-11 43.9 0.2 4.4e-11 42.8 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CBY21333.1 - 0.00083 19.7 0.2 0.0034 17.8 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 CBY21333.1 - 0.002 18.6 0.1 0.0063 16.9 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CBY21333.1 - 0.0044 16.8 0.7 0.0096 15.7 0.2 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit ABC_tran PF00005.27 CBY21333.1 - 0.037 14.5 0.1 0.093 13.3 0.0 1.7 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.13 CBY21333.1 - 0.089 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 CBY21333.1 - 0.17 12.2 0.1 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 CBY21333.1 - 0.19 12.2 0.9 0.34 11.4 0.9 1.8 1 1 0 1 1 1 0 AAA domain Peptidase_S24 PF00717.23 CBY21334.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Peptidase S24-like Cbl_N3 PF02762.14 CBY21335.1 - 4.5e-38 129.0 0.0 8.2e-38 128.1 0.0 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 CBY21335.1 - 7.4e-33 113.1 5.2 1.6e-32 112.1 5.2 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N PF02262.16 CBY21335.1 - 3.8e-28 98.0 0.3 6.9e-28 97.2 0.3 1.3 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Prok-RING_4 PF14447.6 CBY21335.1 - 4.2e-10 39.3 7.5 9.8e-10 38.1 7.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY21335.1 - 6e-09 35.6 6.1 1.3e-08 34.5 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY21335.1 - 3.1e-07 30.6 8.7 7.7e-07 29.3 8.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY21335.1 - 1.5e-06 28.0 8.6 3.1e-06 27.0 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY21335.1 - 2e-05 24.3 9.2 4.5e-05 23.2 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY21335.1 - 0.00076 19.5 5.5 0.0021 18.1 5.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY21335.1 - 0.0034 17.3 6.5 0.0083 16.1 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain SesA PF17107.5 CBY21335.1 - 0.053 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-C3HC4_4 PF15227.6 CBY21335.1 - 0.071 13.3 7.0 0.15 12.2 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 CBY21335.1 - 0.074 12.8 6.9 0.16 11.7 6.9 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 CBY21335.1 - 0.077 13.1 2.2 0.16 12.0 2.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 CBY21335.1 - 0.22 11.7 5.3 1.1 9.4 5.3 2.1 1 1 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 CBY21335.1 - 0.79 9.4 3.9 2.3 7.9 3.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 CBY21335.1 - 0.93 9.8 5.7 2.1 8.7 5.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CBY21335.1 - 6.5 6.6 12.6 1.4 8.7 8.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF5600 PF18150.1 CBY21336.1 - 8.9e-40 135.6 0.5 1.8e-39 134.6 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 CBY21336.1 - 3.7e-18 65.4 0.3 1.7e-17 63.3 0.1 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 CBY21336.1 - 8.2e-18 64.0 3.5 8.2e-18 64.0 3.5 2.3 2 0 0 2 2 2 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 CBY21336.1 - 9.5e-14 51.8 0.0 2.5e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBY21336.1 - 2.1e-07 31.0 0.0 5.6e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 CBY21336.1 - 2.2e-05 23.7 0.1 0.00012 21.4 0.1 2.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBY21336.1 - 0.0023 17.7 0.1 0.024 14.6 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CBY21336.1 - 0.0059 17.0 0.1 0.038 14.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair Roc PF08477.13 CBY21336.1 - 0.0081 16.4 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBY21336.1 - 0.0089 15.4 0.9 0.041 13.2 0.2 2.3 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region EF-hand_8 PF13833.6 CBY21336.1 - 0.009 15.8 0.3 1.3 9.0 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair GTP_EFTU PF00009.27 CBY21336.1 - 0.03 13.9 0.1 0.41 10.2 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Isochorismatase PF00857.20 CBY21336.1 - 0.078 13.1 0.0 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Isochorismatase family AIG1 PF04548.16 CBY21336.1 - 0.1 11.9 0.0 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 AIG1 family EF-hand_5 PF13202.6 CBY21336.1 - 0.11 12.0 0.1 0.28 10.7 0.1 1.7 1 0 0 1 1 1 0 EF hand FeoB_N PF02421.18 CBY21336.1 - 0.12 11.9 0.0 9.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 CBY21336.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CBY21336.1 - 0.19 11.2 1.5 30 4.0 0.2 3.4 3 1 0 3 3 3 0 ADP-ribosylation factor family LRR_9 PF14580.6 CBY21337.1 - 9.5e-12 44.8 0.2 1.2e-11 44.4 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBY21337.1 - 6.4e-06 25.8 6.6 0.001 18.8 0.3 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY21337.1 - 2.2e-05 24.7 7.7 2.7e-05 24.4 0.3 3.0 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) CobT PF06213.12 CBY21337.1 - 2.3 7.5 10.6 3.4 7.0 10.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 CBY21337.1 - 2.8 7.3 12.0 3.7 6.9 12.0 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CBY21337.1 - 3.1 7.0 13.7 3.9 6.7 13.7 1.1 1 0 0 1 1 1 0 BUD22 HMG_box PF00505.19 CBY21338.1 - 0.013 15.9 0.1 0.04 14.3 0.1 1.8 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY21338.1 - 0.093 13.3 0.1 0.093 13.3 0.1 2.0 2 0 0 2 2 2 0 HMG-box domain EcoR124_C PF12008.8 CBY21338.1 - 0.1 12.3 0.1 0.1 12.3 0.1 2.0 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal PDZ PF00595.24 CBY21339.1 - 1.2e-39 134.5 6.4 3.8e-14 52.8 0.1 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CBY21339.1 - 2e-29 101.2 2.8 2.9e-09 36.6 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CBY21339.1 - 1e-22 80.2 2.0 3.6e-07 30.4 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 CBY21339.1 - 8.3e-10 38.6 0.3 2.2e-09 37.3 0.3 1.6 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 CBY21339.1 - 5.9e-07 29.1 0.1 2.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Tricorn_PDZ PF14685.6 CBY21339.1 - 0.00091 19.1 1.7 5.2 7.1 0.0 3.6 3 0 0 3 3 3 2 Tricorn protease PDZ domain Corona_nucleoca PF00937.18 CBY21339.1 - 0.024 13.7 5.0 0.018 14.1 2.5 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein PDZ PF00595.24 CBY21340.1 - 4.5e-39 132.7 4.6 5.4e-14 52.3 0.1 3.7 3 0 0 3 3 3 3 PDZ domain ZU5 PF00791.20 CBY21340.1 - 2.8e-34 117.4 0.0 8.1e-34 115.9 0.0 1.8 1 0 0 1 1 1 1 ZU5 domain PDZ_6 PF17820.1 CBY21340.1 - 4.6e-28 96.8 1.5 4e-09 36.2 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CBY21340.1 - 1.5e-21 76.5 2.2 5.1e-07 29.9 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 CBY21340.1 - 1.5e-09 37.8 0.3 3.1e-09 36.8 0.3 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 CBY21340.1 - 1.2e-06 28.1 0.1 3.5e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Corona_nucleoca PF00937.18 CBY21340.1 - 0.24 10.4 8.3 0.16 11.0 5.7 2.0 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein WD40 PF00400.32 CBY21342.1 - 1.8e-06 28.5 7.7 0.88 10.5 0.3 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21342.1 - 0.0032 17.7 0.0 0.0084 16.4 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PI-PLC-X PF00388.19 CBY21343.1 - 1.5e-56 190.0 0.0 2.1e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY21343.1 - 1.4e-33 115.6 0.1 2.3e-33 115.0 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Blo-t-5 PF11642.8 CBY21344.1 - 0.022 14.7 1.9 0.077 13.0 1.9 1.8 1 1 0 1 1 1 0 Mite allergen Blo t 5 DUF2312 PF10073.9 CBY21344.1 - 0.057 13.1 4.6 0.06 13.0 0.8 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) GDI PF00996.18 CBY21345.1 - 5.6e-205 680.9 0.0 6.4e-205 680.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor RRM_1 PF00076.22 CBY21346.1 - 1.4e-16 60.1 0.0 2.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 CBY21346.1 - 0.054 12.4 0.9 0.065 12.1 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Glyco_hydro_38N PF01074.22 CBY21346.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain Homeodomain PF00046.29 CBY21347.1 - 1.8e-21 75.7 3.3 3.6e-21 74.8 3.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY21347.1 - 0.0091 15.9 0.1 0.021 14.7 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF4542 PF15075.6 CBY21347.1 - 0.096 13.1 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) OTOS PF15182.6 CBY21347.1 - 0.16 11.9 0.4 0.43 10.5 0.2 1.7 2 0 0 2 2 2 0 Otospiralin Auxin_canalis PF05703.11 CBY21347.1 - 0.46 10.4 4.1 0.31 10.9 0.8 1.8 1 1 1 2 2 2 0 Auxin canalisation Peptidase_M16_C PF05193.21 CBY21349.1 - 5e-08 33.2 0.1 1.2e-07 31.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CBY21349.1 - 1.7e-07 31.3 0.1 3e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) MRP-L28 PF09812.9 CBY21350.1 - 0.13 12.4 1.0 5.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Rx_N PF18052.1 CBY21350.1 - 0.16 12.2 1.3 0.25 11.7 0.2 1.8 2 0 0 2 2 2 0 Rx N-terminal domain DUF3539 PF12058.8 CBY21351.1 - 0.03 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) Homeodomain PF00046.29 CBY21352.1 - 7.1e-11 41.8 2.2 1.3e-10 40.9 2.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY21352.1 - 0.00022 21.0 0.6 0.00022 21.0 0.6 1.8 2 0 0 2 2 2 1 Homeobox KN domain zf-C2H2 PF00096.26 CBY21353.1 - 9.7e-17 60.4 29.1 1.2e-07 31.8 0.7 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY21353.1 - 5.6e-15 55.0 9.1 2.9e-09 36.9 2.5 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY21353.1 - 1.6e-09 37.8 29.2 0.00018 22.1 0.5 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBY21353.1 - 2.7e-05 24.4 3.4 2.7e-05 24.4 3.4 1.5 2 0 0 2 2 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CBY21353.1 - 3.9e-05 23.8 2.9 0.98 9.8 0.0 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY21353.1 - 5.4e-05 23.1 12.8 0.022 14.7 0.2 3.4 3 1 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 CBY21353.1 - 0.0016 19.1 15.2 0.0041 17.7 0.2 3.6 2 2 2 4 4 4 2 FOXP coiled-coil domain zf-Di19 PF05605.12 CBY21353.1 - 0.0057 16.9 2.1 0.0057 16.9 2.1 3.8 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 CBY21353.1 - 0.0066 16.3 17.1 0.081 12.9 0.2 3.3 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-met PF12874.7 CBY21353.1 - 0.021 15.2 5.4 2 8.9 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 CBY21353.1 - 0.027 15.2 2.0 0.027 15.2 2.0 2.7 2 1 1 3 3 3 0 TRAF-type zinc finger zf-H2C2_5 PF13909.6 CBY21353.1 - 0.041 13.7 0.0 0.041 13.7 0.0 4.1 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 CBY21353.1 - 0.27 11.4 2.0 12 6.0 0.1 2.4 2 1 0 2 2 2 0 Aberrant zinc-finger PyrI_C PF02748.15 CBY21353.1 - 0.38 10.7 0.2 0.38 10.7 0.2 3.3 3 1 1 4 4 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 CBY21353.1 - 0.72 9.9 17.4 2.3 8.3 0.2 3.6 2 2 1 3 3 3 0 BED zinc finger IBR PF01485.21 CBY21353.1 - 5.9 7.2 16.0 0.51 10.6 4.7 3.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_2 PF12756.7 CBY21353.1 - 7.7 6.9 12.3 2.6 8.4 1.7 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SIX1_SD PF16878.5 CBY21354.1 - 1.3e-46 157.7 0.1 2.7e-46 156.7 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CBY21354.1 - 9.8e-15 54.2 0.8 1.2e-13 50.6 0.3 2.4 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY21354.1 - 2.5e-13 49.7 1.0 1e-12 47.7 0.4 2.3 2 0 0 2 2 2 1 Homeobox KN domain HTH_3 PF01381.22 CBY21354.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.8 CBY21354.1 - 0.025 14.1 0.2 0.069 12.6 0.1 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 CBY21354.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Crp_2 PF13545.6 CBY21354.1 - 0.13 12.3 0.0 23 5.0 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Spt20 PF12090.8 CBY21354.1 - 3.1 7.4 12.3 0.022 14.4 2.4 2.1 2 0 0 2 2 2 0 Spt20 family zf-C2H2 PF00096.26 CBY21355.1 - 1.8e-08 34.4 5.0 0.0023 18.3 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY21355.1 - 1.6e-05 25.1 0.9 0.031 14.6 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Nepo_coat PF03391.15 CBY21355.1 - 0.0015 18.0 0.2 0.006 16.1 0.0 1.9 2 0 0 2 2 2 1 Nepovirus coat protein, central domain zf-met PF12874.7 CBY21355.1 - 0.0078 16.6 0.3 0.0078 16.6 0.3 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY21355.1 - 0.012 16.3 15.9 0.033 15.0 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY21355.1 - 0.035 14.5 0.3 0.035 14.5 0.3 2.2 2 1 1 3 3 3 0 Zinc-finger double domain Transpos_assoc PF13963.6 CBY21355.1 - 6.9 7.1 8.0 3.1 8.2 4.4 2.1 1 1 1 2 2 2 0 Transposase-associated domain Acetyltransf_1 PF00583.25 CBY21356.1 - 7e-13 48.8 0.1 1.2e-12 48.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY21356.1 - 5.3e-08 33.2 0.1 1.6e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY21356.1 - 2.6e-06 27.4 0.0 5.9e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY21356.1 - 4.8e-05 23.5 0.0 9.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY21356.1 - 0.0078 16.2 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 CBY21356.1 - 0.0084 16.2 0.1 0.028 14.5 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 CBY21356.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Myb_DNA-bind_6 PF13921.6 CBY21356.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-C2H2 PF00096.26 CBY21357.1 - 0.026 14.9 1.2 0.026 14.9 1.2 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type GATA PF00320.27 CBY21357.1 - 0.19 11.4 18.1 0.76 9.4 0.8 4.7 5 0 0 5 5 5 0 GATA zinc finger zf-C2H2_jaz PF12171.8 CBY21357.1 - 1.3 9.4 5.9 0.26 11.6 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HNH PF01844.23 CBY21357.1 - 7.3 6.9 10.1 0.19 12.0 1.9 2.6 2 0 0 2 2 2 0 HNH endonuclease RRM_1 PF00076.22 CBY21358.1 - 3.3e-33 113.3 0.7 4e-17 61.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY21358.1 - 6.7e-09 35.7 0.5 0.0046 17.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CBY21358.1 - 0.012 15.7 0.2 0.1 12.7 0.1 2.2 2 0 0 2 2 2 0 RNA binding motif OB_RNB PF08206.11 CBY21358.1 - 0.02 14.5 0.8 1.7 8.4 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 CBY21358.1 - 0.039 14.2 0.1 1.2 9.3 0.0 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Vps36_ESCRT-II PF11605.8 CBY21359.1 - 4e-06 26.9 0.0 4.3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 CBY21360.1 - 4.1e-22 78.6 0.2 4.6e-22 78.5 0.2 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Striatin PF08232.12 CBY21361.1 - 3.9e-41 141.2 1.6 1.9e-39 135.7 1.6 2.4 1 1 0 1 1 1 1 Striatin family G-gamma PF00631.22 CBY21361.1 - 0.13 12.3 0.7 0.35 10.9 0.7 1.7 1 0 0 1 1 1 0 GGL domain DUF4482 PF14818.6 CBY21361.1 - 0.29 12.0 7.0 0.24 12.3 3.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) WD40 PF00400.32 CBY21362.1 - 1.2e-30 105.0 7.9 1.6e-06 28.7 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21362.1 - 3.9e-08 33.5 3.3 2.4 8.5 0.1 5.4 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY21362.1 - 2.7e-06 26.3 0.9 0.58 8.7 0.1 4.0 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CBY21362.1 - 0.02 13.6 0.3 2.8 6.6 0.0 3.2 3 1 0 3 3 3 0 Nup133 N terminal like Brix PF04427.18 CBY21363.1 - 4e-33 115.1 0.2 5.6e-33 114.7 0.2 1.2 1 0 0 1 1 1 1 Brix domain KH_1 PF00013.29 CBY21364.1 - 6.7e-47 157.2 18.5 2.2e-12 46.6 0.3 4.6 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.22 CBY21364.1 - 2.3e-19 69.0 0.0 1.4e-08 34.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.17 CBY21364.1 - 8.8e-12 44.7 8.8 0.046 13.6 0.0 4.7 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 CBY21364.1 - 1.3e-10 41.0 5.2 0.0036 17.1 0.1 4.6 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 CBY21364.1 - 5.3e-07 29.6 7.2 0.93 9.6 0.0 4.7 4 0 0 4 4 4 3 NusA-like KH domain DbpA PF03880.15 CBY21364.1 - 2.1e-06 27.6 3.4 0.015 15.3 0.1 4.1 4 0 0 4 4 4 2 DbpA RNA binding domain RRM_5 PF13893.6 CBY21364.1 - 0.0004 20.0 0.0 0.06 13.0 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY21364.1 - 0.0018 18.1 0.0 0.083 12.8 0.0 2.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 CBY21365.1 - 9.1e-19 66.9 32.2 2.6e-06 27.2 1.0 5.5 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY21365.1 - 2.2e-18 65.7 44.8 6.8e-07 29.1 2.0 6.3 6 0 0 6 6 6 4 Zinc finger domain Torus PF16131.5 CBY21365.1 - 3.2e-14 53.5 27.7 0.00031 21.4 0.5 5.1 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 CBY21365.1 - 2.7e-12 46.2 24.8 1.4e-05 24.8 0.4 5.2 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CBY21365.1 - 3.9e-09 36.7 26.1 7.6e-06 26.1 9.5 3.0 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CBY21365.1 - 0.0042 17.5 34.9 0.17 12.4 2.1 6.1 5 1 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 CBY21365.1 - 0.02 14.9 4.3 0.02 14.9 4.3 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-C3H1 PF10650.9 CBY21365.1 - 0.58 9.9 14.9 0.99 9.2 0.2 4.4 4 0 0 4 4 4 0 Putative zinc-finger domain Ndc1_Nup PF09531.10 CBY21367.1 - 4.7 5.8 4.8 5.4 5.6 4.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pro_isomerase PF00160.21 CBY21368.1 - 2.2e-25 89.8 0.1 2.3e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CBY21369.1 - 1.6e-13 50.3 0.0 3.4e-07 30.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 CBY21369.1 - 0.012 15.9 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 BRCA1-associated protein 2 RRM_occluded PF16842.5 CBY21369.1 - 0.097 12.5 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif AA_permease PF00324.21 CBY21371.1 - 8.7e-68 229.0 32.4 1.1e-67 228.7 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CBY21371.1 - 4.7e-45 154.4 3.1 1.9e-28 99.7 0.9 3.0 1 1 1 2 2 2 2 Solute carrier family 12 MH1 PF03165.16 CBY21372.1 - 3.2e-11 43.3 0.3 5.5e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 MH1 domain CTF_NFI PF00859.18 CBY21372.1 - 0.00037 20.5 1.0 0.00056 19.9 1.0 1.3 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region Rsa3 PF14615.6 CBY21376.1 - 0.11 12.0 1.0 0.28 10.8 1.0 1.6 1 1 0 1 1 1 0 Ribosome-assembly protein 3 EMP24_GP25L PF01105.24 CBY21378.1 - 4e-35 121.4 0.1 4.5e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 CBY21378.1 - 0.0026 18.0 0.1 0.0035 17.6 0.1 1.4 1 0 0 1 1 1 1 SdrD B-like domain DUF4198 PF10670.9 CBY21378.1 - 0.03 14.7 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Pkinase PF00069.25 CBY21379.1 - 6.7e-54 183.0 0.0 8.9e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21379.1 - 2e-37 128.9 0.0 2.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY21379.1 - 0.00075 18.9 0.1 0.0038 16.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Mrx7 PF10906.8 CBY21379.1 - 0.12 12.6 0.1 0.35 11.2 0.1 1.9 1 1 0 1 1 1 0 MIOREX complex component 7 Gemini_AL1 PF00799.20 CBY21381.1 - 0.02 15.3 0.1 0.03 14.7 0.1 1.3 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Gemini_AL1 PF00799.20 CBY21383.1 - 0.099 13.0 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Med28 PF11594.8 CBY21384.1 - 0.059 13.4 0.3 2.5 8.2 0.1 2.3 2 0 0 2 2 2 0 Mediator complex subunit 28 Guanylate_cyc PF00211.20 CBY21385.1 - 3.7e-44 150.5 0.0 6.7e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Tox-MPTase2 PF15638.6 CBY21385.1 - 0.067 12.9 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Pkinase_Tyr PF07714.17 CBY21385.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Glutaminase PF04960.15 CBY21386.1 - 5.1e-117 390.1 0.0 6.3e-117 389.8 0.0 1.1 1 0 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 CBY21386.1 - 5.7e-14 52.2 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain Ank_2 PF12796.7 CBY21386.1 - 1.7e-05 25.3 0.0 4.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY21386.1 - 0.0018 18.6 0.0 0.01 16.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CBY21386.1 - 0.0031 18.0 0.0 0.0066 17.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3718 PF12514.8 CBY21386.1 - 0.078 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) Ank PF00023.30 CBY21386.1 - 0.085 13.3 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat SpoIIM PF01944.17 CBY21389.1 - 0.02 14.9 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein M DUF2968 PF11180.8 CBY21389.1 - 0.13 11.9 15.0 2.4 7.7 5.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Csm1_N PF18504.1 CBY21389.1 - 0.15 12.4 24.0 1.1 9.6 4.8 3.9 3 1 1 4 4 4 0 Csm1 N-terminal domain DUF641 PF04859.12 CBY21389.1 - 0.53 10.6 26.7 1.3 9.4 1.7 3.8 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) Scaffolding_pro PF11418.8 CBY21389.1 - 3 8.5 9.7 0.31 11.6 2.3 2.7 2 1 2 4 4 4 0 Phi29 scaffolding protein ATG16 PF08614.11 CBY21389.1 - 3.3 7.9 18.1 1.4e+02 2.5 18.0 2.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_HK97_TLTM PF06120.11 CBY21389.1 - 7.4 5.7 18.5 42 3.2 15.3 2.7 1 1 1 2 2 2 0 Tail length tape measure protein Chromo PF00385.24 CBY21390.1 - 2.3e-15 56.2 1.8 2.3e-15 56.2 1.8 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PFU PF09070.11 CBY21390.1 - 0.043 14.1 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) DUF4674 PF15719.5 CBY21390.1 - 0.46 10.5 3.6 5.1 7.1 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) Ribosomal_S14 PF00253.21 CBY21391.1 - 1.4e-10 40.8 2.5 1.6e-10 40.6 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PC4 PF02229.16 CBY21392.1 - 2.2e-35 120.0 4.7 8.4e-19 66.9 0.9 2.4 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) CDC45 PF02724.14 CBY21392.1 - 2.5 6.3 5.8 2.9 6.1 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CBY21392.1 - 3.4 6.3 3.5 3.8 6.2 3.5 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 CBY21393.1 - 1.4e-36 126.2 0.0 1.7e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21393.1 - 5.1e-06 25.9 0.0 7.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY21393.1 - 3.2e-05 24.0 0.0 5.9e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY21393.1 - 0.00028 20.3 0.1 0.00042 19.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY21393.1 - 0.0022 16.8 0.0 0.0033 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY21393.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like SNARE_assoc PF09335.11 CBY21395.1 - 3.5e-20 72.7 1.3 3.5e-20 72.7 1.3 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein SpoVAC_SpoVAEB PF03862.13 CBY21395.1 - 0.0045 17.3 0.2 0.17 12.2 0.1 2.4 2 0 0 2 2 2 1 SpoVAC/SpoVAEB sporulation membrane protein UPF0016 PF01169.19 CBY21395.1 - 0.037 14.4 1.1 0.78 10.1 0.6 2.6 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 DUF3504 PF12012.8 CBY21396.1 - 0.15 11.9 0.3 0.15 11.9 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3504) TFIIF_alpha PF05793.12 CBY21396.1 - 0.16 10.6 22.4 0.18 10.3 22.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 CBY21396.1 - 1.4 7.7 23.7 1.7 7.4 23.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 CBY21396.1 - 2.7 6.7 11.8 3 6.5 11.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.9 CBY21396.1 - 5.3 5.5 13.7 5.4 5.5 13.7 1.2 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 CBY21396.1 - 7.7 4.7 8.2 9.9 4.4 8.2 1.2 1 0 0 1 1 1 0 Menin Steroid_dh PF02544.16 CBY21397.1 - 3.1e-08 33.8 1.3 5.8e-08 32.9 1.3 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase BAG PF02179.16 CBY21398.1 - 3.1e-10 40.3 5.9 3.1e-10 40.3 5.9 2.4 2 0 0 2 2 2 1 BAG domain Baculo_PEP_C PF04513.12 CBY21398.1 - 0.029 14.4 0.0 4.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Corona_nucleoca PF00937.18 CBY21398.1 - 0.085 11.9 4.3 0.12 11.4 4.3 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CDC45 PF02724.14 CBY21398.1 - 4.1 5.6 15.4 4.7 5.4 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF573 PF04504.14 CBY21398.1 - 5.3 7.8 10.8 0.32 11.7 3.5 2.6 2 2 1 3 3 3 0 Protein of unknown function, DUF573 Alpha_kinase PF02816.18 CBY21399.1 - 0.075 13.2 2.3 0.22 11.6 0.2 2.7 3 0 0 3 3 3 0 Alpha-kinase family TolA_bind_tri PF16331.5 CBY21400.1 - 0.0012 18.9 3.3 0.0028 17.7 3.3 1.7 1 0 0 1 1 1 1 TolA binding protein trimerisation TSC22 PF01166.18 CBY21400.1 - 0.0023 18.2 1.0 0.0084 16.4 1.0 2.0 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF641 PF04859.12 CBY21400.1 - 0.0037 17.6 2.5 0.0037 17.6 2.5 2.1 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) DUF3450 PF11932.8 CBY21400.1 - 0.0068 15.7 2.7 0.0068 15.7 2.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Csm1_N PF18504.1 CBY21400.1 - 0.013 15.8 2.7 0.013 15.8 2.7 2.4 2 1 0 2 2 2 0 Csm1 N-terminal domain Troponin PF00992.20 CBY21400.1 - 0.018 15.3 5.0 0.018 15.3 5.0 2.4 2 1 0 2 2 2 0 Troponin BRE1 PF08647.11 CBY21400.1 - 0.02 15.0 3.0 0.02 15.0 3.0 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 CBY21400.1 - 0.022 14.6 1.9 0.022 14.6 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TLE_N PF03920.15 CBY21400.1 - 0.055 13.5 1.4 0.13 12.4 1.4 1.6 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF2205 PF10224.9 CBY21400.1 - 0.4 10.7 6.1 0.23 11.4 1.0 2.5 1 1 1 2 2 2 0 Short coiled-coil protein YabA PF06156.13 CBY21400.1 - 0.92 10.2 9.3 0.22 12.2 1.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 CBY21400.1 - 1.7 9.2 11.5 0.21 12.1 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 AAA_23 PF13476.6 CBY21400.1 - 1.8 9.0 11.6 2.8 8.4 11.6 1.2 1 0 0 1 1 1 0 AAA domain DUF1192 PF06698.11 CBY21400.1 - 2.5 8.2 9.3 0.55 10.3 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF4407 PF14362.6 CBY21400.1 - 3.5 6.9 9.7 1.3 8.3 6.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cauli_AT PF03233.13 CBY21400.1 - 4.3 7.2 9.9 0.37 10.7 0.4 2.2 2 0 0 2 2 2 0 Aphid transmission protein DivIC PF04977.15 CBY21400.1 - 6.5 6.6 13.8 0.076 12.8 5.6 2.0 2 1 1 3 3 3 0 Septum formation initiator FAM76 PF16046.5 CBY21400.1 - 8.4 5.7 12.8 15 4.9 12.8 1.4 1 1 0 1 1 1 0 FAM76 protein RNA_pol_Rpb4 PF03874.16 CBY21401.1 - 5e-20 72.1 6.2 5.6e-20 71.9 6.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 RcpC PF16976.5 CBY21401.1 - 0.022 14.8 2.5 0.04 14.0 2.5 1.4 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB DUF4946 PF16304.5 CBY21401.1 - 0.044 13.5 0.4 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4946) DUF4473 PF14747.6 CBY21401.1 - 0.063 13.8 1.7 0.14 12.7 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4473) Toprim_C_rpt PF13368.6 CBY21401.1 - 0.26 11.3 1.4 0.49 10.4 1.4 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Peptidase_S24 PF00717.23 CBY21402.1 - 3.7e-06 26.8 0.7 9.4e-06 25.5 0.7 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CBY21402.1 - 0.00084 19.1 0.0 0.057 13.2 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DDRGK PF09756.9 CBY21403.1 - 1.2e-49 168.5 36.4 1.2e-49 168.5 36.4 1.5 2 0 0 2 2 2 1 DDRGK domain Raftlin PF15250.6 CBY21403.1 - 1.3 7.7 12.3 1.5 7.5 12.3 1.2 1 0 0 1 1 1 0 Raftlin DUF4661 PF15576.6 CBY21403.1 - 5.1 6.9 9.8 7.2 6.5 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF2691 PF10903.8 CBY21404.1 - 0.07 13.0 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) DUF1325 PF07039.11 CBY21405.1 - 3.3e-30 104.9 0.0 6.5e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_2 PF18104.1 CBY21405.1 - 0.03 14.0 0.1 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 CBY21405.1 - 0.037 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 CBY21405.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 CBY21405.1 - 0.078 12.7 0.2 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 PRD PF00874.20 CBY21405.1 - 0.11 12.8 1.3 0.18 12.1 1.3 1.4 1 0 0 1 1 1 0 PRD domain DUF4618 PF15397.6 CBY21405.1 - 0.16 11.4 4.8 0.21 11.0 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Chromo PF00385.24 CBY21406.1 - 8.4e-16 57.6 2.7 6.4e-15 54.8 2.6 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CBY21406.1 - 6e-05 23.1 0.4 0.0012 18.9 0.0 2.6 2 0 0 2 2 2 1 Chromo shadow domain Homeodomain PF00046.29 CBY21407.1 - 3e-22 78.2 4.3 6.9e-22 77.1 4.3 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY21407.1 - 0.022 14.6 0.2 0.022 14.6 0.2 2.6 3 0 0 3 3 3 0 Homeobox KN domain Homez PF11569.8 CBY21407.1 - 0.069 12.6 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF4685 PF15737.5 CBY21407.1 - 0.36 11.3 5.7 0.49 10.8 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Spt20 PF12090.8 CBY21407.1 - 1.1 8.9 11.7 20 4.7 9.4 2.2 2 0 0 2 2 2 0 Spt20 family DUF4404 PF14357.6 CBY21407.1 - 4.2 8.1 8.4 4.4 8.0 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3138 PF11336.8 CBY21407.1 - 9.6 4.7 11.0 14 4.1 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PLAC8 PF04749.17 CBY21409.1 - 1.3e-17 64.6 15.6 2.5e-17 63.7 15.6 1.4 1 1 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 CBY21411.1 - 0.0081 17.1 0.1 0.012 16.6 0.1 1.2 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 CBY21412.1 - 1.4e-05 26.0 12.9 2.3e-05 25.3 12.9 1.3 1 1 0 1 1 1 1 PLAC8 family EF-hand_6 PF13405.6 CBY21413.1 - 1.3e-07 31.0 0.3 0.00017 21.2 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBY21413.1 - 1.4e-07 31.8 8.4 8.8e-05 22.9 0.2 4.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY21413.1 - 3.8e-07 29.2 0.6 4.6e-05 22.7 0.1 3.0 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CBY21413.1 - 0.00021 20.6 0.3 0.00093 18.6 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CBY21413.1 - 0.0011 19.2 0.4 0.024 14.9 0.1 3.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBY21413.1 - 0.01 15.6 0.0 0.046 13.6 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain pair VGCC_beta4Aa_N PF12052.8 CBY21413.1 - 0.055 13.6 0.5 0.055 13.6 0.5 2.8 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal EF-hand_14 PF17959.1 CBY21413.1 - 0.084 13.2 0.2 0.084 13.2 0.2 4.4 4 1 1 5 5 5 0 EF-hand domain RST PF12174.8 CBY21413.1 - 0.11 12.5 0.4 0.59 10.1 0.1 2.5 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain MbeD_MobD PF04899.12 CBY21413.1 - 0.33 11.1 10.0 8 6.7 5.6 4.1 3 0 0 3 3 3 0 MbeD/MobD like IP_trans PF02121.18 CBY21414.1 - 9.5e-41 140.0 2.2 1.2e-40 139.7 2.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Phospholip_A2_1 PF00068.19 CBY21415.1 - 1.2e-15 58.0 5.5 1.6e-15 57.5 5.5 1.2 1 0 0 1 1 1 1 Phospholipase A2 SH3_1 PF00018.28 CBY21416.1 - 4.9e-09 35.7 0.0 8.6e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY21416.1 - 6.2e-06 26.0 0.0 9.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY21416.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4660 PF15559.6 CBY21416.1 - 0.01 16.1 0.9 0.042 14.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) SH3_3 PF08239.11 CBY21416.1 - 0.033 14.5 0.2 0.057 13.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Draxin PF15550.6 CBY21416.1 - 0.073 12.9 2.4 0.086 12.7 2.4 1.1 1 0 0 1 1 1 0 Draxin SWIRM-assoc_1 PF16495.5 CBY21417.1 - 0.015 15.2 1.0 0.017 15.0 1.0 1.1 1 0 0 1 1 1 0 SWIRM-associated region 1 LUC7 PF03194.15 CBY21417.1 - 0.017 14.8 0.2 0.017 14.8 0.2 1.0 1 0 0 1 1 1 0 LUC7 N_terminus FemAB_like PF04339.12 CBY21417.1 - 0.088 11.9 2.3 0.1 11.7 2.3 1.0 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition HemY_N PF07219.13 CBY21419.1 - 1.2 9.3 6.8 1.8 8.8 6.8 1.3 1 0 0 1 1 1 0 HemY protein N-terminus ANAPC_CDC26 PF10471.9 CBY21419.1 - 4.7 8.1 13.2 13 6.7 8.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 zf-C3HC4_2 PF13923.6 CBY21420.1 - 9e-05 22.2 16.1 9e-05 22.2 16.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY21420.1 - 0.00096 19.0 11.2 0.0018 18.1 11.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY21420.1 - 0.0012 18.7 16.5 0.0031 17.4 16.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY21420.1 - 0.0029 17.6 9.2 0.0087 16.1 9.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY21420.1 - 0.0072 16.2 16.7 0.0072 16.2 16.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY21420.1 - 0.009 16.1 12.0 0.033 14.4 12.0 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBY21420.1 - 0.011 16.1 14.9 0.011 16.1 14.9 2.0 2 0 0 2 2 2 0 Ring finger domain ZapB PF06005.12 CBY21420.1 - 0.025 15.0 0.1 0.036 14.5 0.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 CBY21420.1 - 0.028 15.0 6.0 0.034 14.8 6.0 1.1 1 0 0 1 1 1 0 Initiation control protein YabA PCNP PF15473.6 CBY21420.1 - 0.078 13.7 0.2 0.11 13.2 0.2 1.3 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family zf-RING_4 PF14570.6 CBY21420.1 - 0.19 11.5 13.8 0.85 9.5 13.5 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS91 PF14319.6 CBY21420.1 - 0.39 10.8 11.9 0.098 12.7 6.8 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain zinc-ribbons_6 PF07191.12 CBY21420.1 - 0.65 10.0 12.9 0.28 11.2 9.9 1.9 2 0 0 2 2 2 0 zinc-ribbons zf-UDP PF14569.6 CBY21420.1 - 0.74 10.0 9.6 8.1 6.6 9.6 2.2 1 1 1 2 2 2 0 Zinc-binding RING-finger DUF2321 PF10083.9 CBY21420.1 - 9.6 5.8 11.7 1.3 8.7 6.4 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Rap_GAP PF02145.15 CBY21421.1 - 1.8e-54 184.1 0.0 6.1e-54 182.4 0.0 1.9 1 0 0 1 1 1 1 Rap/ran-GAP MRP-S24 PF14955.6 CBY21421.1 - 0.063 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 Sugar_tr PF00083.24 CBY21422.1 - 8.7e-31 107.3 14.7 1.2e-30 106.8 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY21422.1 - 1.2e-18 67.2 34.6 3.4e-12 46.0 6.9 2.4 2 1 0 3 3 3 2 Major Facilitator Superfamily DUF1440 PF07274.12 CBY21422.1 - 0.033 14.5 2.3 0.082 13.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) IL3Ra_N PF18611.1 CBY21422.1 - 0.053 13.5 1.3 0.47 10.5 2.0 2.1 2 0 0 2 2 2 0 IL-3 receptor alpha chain N-terminal domain zf-met PF12874.7 CBY21423.1 - 2.3e-05 24.6 1.2 4.9e-05 23.6 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY21423.1 - 0.00032 20.9 2.8 0.00066 19.9 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding MSA-2c PF12238.8 CBY21423.1 - 0.0026 17.8 1.0 0.0036 17.4 1.0 1.2 1 0 0 1 1 1 1 Merozoite surface antigen 2c zf-C2H2 PF00096.26 CBY21423.1 - 0.0059 17.0 0.5 0.01 16.3 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY21423.1 - 0.0075 16.6 1.2 0.0075 16.6 1.2 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NES_C_h PF18208.1 CBY21423.1 - 0.027 14.8 2.9 0.032 14.5 2.9 1.2 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain zf-C2H2_4 PF13894.6 CBY21423.1 - 0.074 13.9 0.1 0.15 12.9 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4337 PF14235.6 CBY21423.1 - 5.6 7.0 6.1 6.5 6.8 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP-synt_E PF05680.12 CBY21423.1 - 5.9 7.3 8.5 7.7 6.9 8.2 1.4 1 1 0 1 1 1 0 ATP synthase E chain CUB PF00431.20 CBY21424.1 - 7.1e-11 42.4 0.2 3.5e-09 37.0 0.2 2.5 1 1 0 1 1 1 1 CUB domain ShK PF01549.24 CBY21425.1 - 2.7e-10 40.6 24.4 2.8e-06 27.8 8.2 5.0 5 1 0 5 5 5 2 ShK domain-like TSP_1 PF00090.19 CBY21425.1 - 2.6e-09 37.2 32.0 1.2e-07 31.8 12.6 4.4 4 1 0 4 4 4 2 Thrombospondin type 1 domain ERM PF00769.19 CBY21426.1 - 1.3e-26 93.9 10.5 3.4e-25 89.3 1.4 2.3 2 0 0 2 2 2 2 Ezrin/radixin/moesin family RhoGEF67_u1 PF16615.5 CBY21426.1 - 0.15 12.6 0.4 0.15 12.6 0.4 3.2 3 0 0 3 3 3 0 Unstructured region one on RhoGEF 6 and 7 BicD PF09730.9 CBY21427.1 - 0.045 12.2 31.3 0.05 12.0 31.3 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D ERM PF00769.19 CBY21427.1 - 0.51 10.1 58.4 2.9 7.6 58.4 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FERM_M PF00373.18 CBY21428.1 - 2.4e-28 98.9 0.4 4.8e-28 97.9 0.4 1.6 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 CBY21428.1 - 1.3e-25 89.6 0.2 1.2e-24 86.5 0.0 2.4 2 1 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CBY21428.1 - 7.9e-15 54.6 0.3 6.8e-14 51.6 0.2 2.5 3 0 0 3 3 3 1 FERM N-terminal domain RRM_1 PF00076.22 CBY21429.1 - 5e-12 45.5 0.0 7.7e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY21429.1 - 0.0035 16.9 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4269 PF14091.6 CBY21431.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) EMP24_GP25L PF01105.24 CBY21431.1 - 0.059 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Dynamin_N PF00350.23 CBY21432.1 - 1.4e-09 38.2 0.1 1.9e-08 34.6 0.1 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBY21432.1 - 5.9e-08 32.8 0.0 1.1e-07 31.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY21432.1 - 0.00046 19.8 0.2 0.001 18.6 0.0 1.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY21432.1 - 0.0042 17.0 0.3 0.034 14.1 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 CBY21432.1 - 0.005 16.2 0.6 1.2 8.4 0.0 2.5 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 CBY21432.1 - 0.0097 16.1 0.1 0.024 14.9 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CBY21432.1 - 0.011 15.0 0.2 0.051 12.9 0.1 2.0 2 1 0 2 2 2 0 Septin KAP_NTPase PF07693.14 CBY21432.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Erf4 PF10256.9 CBY21433.1 - 2.1e-17 63.3 0.1 2.5e-17 63.0 0.1 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Ada3 PF10198.9 CBY21434.1 - 0.011 15.9 13.0 0.015 15.4 11.7 1.9 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 TAFH PF07531.14 CBY21435.1 - 1.2e-21 76.6 6.4 6.1e-21 74.3 3.5 3.0 2 1 0 2 2 2 1 NHR1 homology to TAF TAF4 PF05236.14 CBY21435.1 - 1.5e-20 74.1 16.7 3.3e-18 66.4 13.9 2.7 2 1 1 3 3 3 2 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 CBY21435.1 - 0.017 14.9 0.1 0.017 14.9 0.1 2.6 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit BBL5 PF07289.11 CBY21436.1 - 7.3e-117 390.1 0.1 8.3e-117 389.9 0.1 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 CBY21436.1 - 0.0017 18.5 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 CBY21436.1 - 0.017 15.4 0.0 9.7 6.6 0.0 2.3 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain SH3_11 PF18103.1 CBY21437.1 - 0.045 13.9 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain zf-Di19 PF05605.12 CBY21437.1 - 0.1 12.9 0.8 0.19 12.0 0.1 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF5089 PF17002.5 CBY21438.1 - 2.2e-06 27.7 3.7 4.2e-06 26.8 3.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) SNAP-25 PF00835.19 CBY21438.1 - 5e-06 26.7 2.2 6.9e-06 26.3 0.8 2.1 2 0 0 2 2 2 1 SNAP-25 family V-SNARE_C PF12352.8 CBY21438.1 - 0.0014 18.9 4.6 0.034 14.4 0.8 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBY21438.1 - 0.017 15.0 0.9 0.042 13.8 0.8 1.6 2 0 0 2 2 2 0 Sec20 SNARE PF05739.19 CBY21438.1 - 0.053 13.5 1.6 0.17 11.9 1.6 2.0 1 1 0 1 1 1 0 SNARE domain UPF0242 PF06785.11 CBY21438.1 - 0.12 12.5 4.3 0.53 10.4 2.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CBY21438.1 - 0.26 11.3 2.1 4.6 7.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CBY21438.1 - 0.28 11.6 3.0 12 6.4 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 CBY21438.1 - 0.54 10.5 6.6 0.54 10.5 0.9 2.9 2 1 1 3 3 3 0 Haemolysin XhlA GAS PF13851.6 CBY21438.1 - 1.1 8.6 7.7 3.4 7.0 0.0 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4813 PF16072.5 CBY21439.1 - 0.18 11.4 9.7 0.24 11.0 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) HCO3_cotransp PF00955.21 CBY21440.1 - 6.6e-217 721.3 9.9 8.1e-217 721.0 9.9 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 CBY21440.1 - 4.4e-33 115.2 0.0 6.4e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Cofilin_ADF PF00241.20 CBY21441.1 - 4.5e-33 113.6 0.3 6.2e-17 61.5 0.0 2.3 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pkinase PF00069.25 CBY21442.1 - 1.4e-55 188.6 0.0 2e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Guanylate_kin PF00625.21 CBY21442.1 - 6.3e-43 146.6 0.0 9.5e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase Pkinase_Tyr PF07714.17 CBY21442.1 - 4e-24 85.3 0.0 6.4e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.24 CBY21442.1 - 5.2e-09 36.3 0.1 1.3e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 CBY21442.1 - 4.9e-05 22.9 0.2 0.006 16.2 0.0 3.2 3 0 0 3 3 3 1 SH3 domain PDZ_6 PF17820.1 CBY21442.1 - 0.0046 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 CBY21442.1 - 0.0053 16.4 0.0 0.035 13.8 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain PDZ_2 PF13180.6 CBY21442.1 - 0.022 15.1 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain ABC_transp_aux PF09822.9 CBY21443.1 - 1.9e-08 34.1 0.0 1e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 CBY21443.1 - 2.5e-05 23.3 0.0 0.032 13.1 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.6 CBY21443.1 - 0.003 18.0 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) DUF2194 PF09960.9 CBY21443.1 - 0.031 12.6 0.1 0.043 12.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Adaptin_N PF01602.20 CBY21444.1 - 4.8e-121 404.9 11.8 6.9e-121 404.4 11.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CBY21444.1 - 6.6e-27 93.9 0.0 1.7e-26 92.7 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CBY21444.1 - 3.2e-11 43.5 0.5 1.2e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 CBY21444.1 - 3.4e-06 27.2 1.0 0.0007 19.7 0.0 3.3 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY21444.1 - 4.4e-05 23.8 4.3 0.00013 22.3 0.6 3.5 2 2 1 3 3 3 1 HEAT repeats HEAT PF02985.22 CBY21444.1 - 0.0024 18.0 1.7 32 5.1 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat DRIM PF07539.12 CBY21444.1 - 0.0072 14.7 3.8 0.064 11.6 1.9 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis B2-adapt-app_C PF09066.10 CBY21444.1 - 0.046 13.8 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain CNOT11 PF10155.9 CBY21444.1 - 0.27 11.4 2.4 3.6 7.8 0.2 3.0 2 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 RRM_1 PF00076.22 CBY21445.1 - 1.1e-52 175.7 1.8 5.5e-21 74.2 0.2 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY21445.1 - 1.3e-06 28.5 0.1 0.15 12.1 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 CBY21445.1 - 4.7e-06 26.2 1.9 0.31 10.6 0.2 3.3 1 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY21445.1 - 0.004 17.1 0.3 0.38 10.8 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 CBY21445.1 - 0.015 15.3 0.4 0.77 9.8 0.0 3.2 3 1 0 3 3 3 0 RNA binding domain GLTSCR1 PF15249.6 CBY21446.1 - 1.1e-22 80.4 2.8 2.1e-22 79.5 2.8 1.5 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein FXMR_C2 PF16098.5 CBY21446.1 - 0.39 11.2 3.5 0.99 9.9 0.1 2.8 3 0 0 3 3 3 0 Fragile X-related mental retardation protein C-terminal region 2 DIX PF00778.17 CBY21447.1 - 3.9e-28 97.1 2.6 4.4e-28 96.9 1.4 1.8 2 0 0 2 2 2 1 DIX domain PDZ PF00595.24 CBY21447.1 - 2.5e-18 66.2 0.7 2.5e-18 66.2 0.7 1.8 2 0 0 2 2 2 1 PDZ domain DEP PF00610.21 CBY21447.1 - 5.4e-16 58.4 0.1 1.5e-15 57.0 0.1 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled PF02377.15 CBY21447.1 - 2e-13 51.1 13.0 2e-13 51.1 13.0 2.4 2 1 0 2 2 2 1 Dishevelled specific domain PDZ_6 PF17820.1 CBY21447.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY21447.1 - 0.0023 18.2 0.1 0.0056 17.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.12 CBY21447.1 - 0.008 15.7 0.2 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Bacterial shufflon protein, N-terminal constant region Lamp PF01299.17 CBY21448.1 - 2.6e-13 50.1 3.7 5e-09 36.1 2.6 2.2 2 0 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 CBY21448.1 - 0.00056 19.8 0.7 0.037 13.9 0.1 2.7 2 1 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Galactosyl_T PF01762.21 CBY21449.1 - 3.6e-29 102.0 0.0 1e-28 100.5 0.0 1.8 1 1 0 1 1 1 1 Galactosyltransferase Acyl-CoA_dh_1 PF00441.24 CBY21450.1 - 1.3e-35 122.9 0.1 1.9e-35 122.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY21450.1 - 3.7e-28 97.6 0.0 6.4e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY21450.1 - 5.1e-23 81.9 0.0 3.2e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY21450.1 - 1.2e-12 48.2 0.0 1.8e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBY21450.1 - 0.0026 17.5 0.0 0.014 15.1 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MT PF12777.7 CBY21451.1 - 5.1e-172 571.6 6.9 1.3e-171 570.2 6.9 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DHC_N1 PF08385.12 CBY21451.1 - 2.2e-158 528.4 6.6 2.2e-158 528.4 6.6 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CBY21451.1 - 3.1e-154 512.8 0.0 9.4e-153 507.9 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBY21451.1 - 5.6e-126 420.8 14.3 5.6e-126 420.8 14.3 4.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBY21451.1 - 3.3e-99 331.4 0.1 3.2e-98 328.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBY21451.1 - 1.4e-96 323.3 0.2 5.3e-96 321.5 0.1 2.2 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBY21451.1 - 5.6e-86 287.2 0.3 3.7e-85 284.5 0.2 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBY21451.1 - 4.6e-77 257.6 0.3 4.3e-70 234.9 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBY21451.1 - 4.7e-53 179.4 0.0 1.4e-52 177.8 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBY21451.1 - 8.7e-39 131.8 3.8 2.7e-38 130.2 0.4 3.7 3 0 0 3 3 3 1 AAA+ lid domain Dynein_heavy PF03028.15 CBY21451.1 - 2.5e-37 127.6 0.0 8e-36 122.7 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CBY21451.1 - 1.7e-26 92.8 0.2 1.1e-25 90.1 0.2 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBY21451.1 - 2.3e-24 86.0 0.0 3.7e-11 43.2 0.0 6.3 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY21451.1 - 3.6e-09 37.2 1.1 0.044 14.2 0.0 5.9 5 0 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 CBY21451.1 - 1.3e-07 32.0 1.1 0.66 10.2 0.0 5.5 6 0 0 6 6 4 2 AAA domain AAA_18 PF13238.6 CBY21451.1 - 1.2e-05 25.8 0.0 0.27 11.8 0.0 4.6 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 CBY21451.1 - 1.8e-05 25.2 0.4 0.79 10.2 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBY21451.1 - 2.1e-05 24.3 0.8 0.35 10.5 0.0 3.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CBY21451.1 - 0.00035 20.5 0.0 0.3 11.0 0.0 3.7 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 CBY21451.1 - 0.00037 20.9 1.8 3.7 7.9 0.0 4.0 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 CBY21451.1 - 0.0021 17.8 0.0 0.39 10.4 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.16 CBY21451.1 - 0.0031 17.0 0.8 8 5.9 0.0 4.3 4 0 0 4 4 4 0 PhoH-like protein AAA_29 PF13555.6 CBY21451.1 - 0.0095 15.7 0.3 26 4.6 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CBY21451.1 - 0.01 15.3 0.3 10 5.4 0.0 4.3 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI Pox_A32 PF04665.12 CBY21451.1 - 0.015 14.8 0.1 0.3 10.5 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein DUF2075 PF09848.9 CBY21451.1 - 0.028 13.7 0.0 6 6.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CBY21451.1 - 0.031 14.8 0.1 29 5.1 0.0 3.9 4 0 0 4 4 2 0 ABC transporter ATP_bind_1 PF03029.17 CBY21451.1 - 0.032 14.0 3.1 0.18 11.6 0.1 3.4 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 CBY21451.1 - 0.033 14.4 0.1 12 6.1 0.0 3.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CBY21451.1 - 0.044 13.5 0.1 11 5.7 0.0 3.9 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 CBY21451.1 - 0.05 13.6 1.1 2.3 8.3 0.0 3.0 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 CBY21451.1 - 0.053 13.3 0.0 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 CBY21451.1 - 0.065 12.3 0.0 6.7 5.7 0.0 3.5 3 0 0 3 3 3 0 Type II/IV secretion system protein Ploopntkinase3 PF18751.1 CBY21451.1 - 0.067 13.1 0.0 0.78 9.6 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 CBY21451.1 - 0.094 13.1 0.1 1.3e+02 3.0 0.0 3.9 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 CBY21451.1 - 0.16 12.1 2.1 13 6.0 0.0 3.9 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 CBY21451.1 - 0.6 9.4 4.2 18 4.5 0.0 4.3 5 0 0 5 5 4 0 Zeta toxin TagA PF12561.8 CBY21452.1 - 0.093 13.1 1.4 3.9 7.9 0.2 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain Ycf70 PF17382.2 CBY21452.1 - 0.11 12.9 2.4 0.25 11.8 2.4 1.6 1 0 0 1 1 1 0 Uncharacterized Ycf70-like Casc1_N PF15927.5 CBY21452.1 - 0.31 10.7 9.1 0.56 9.9 9.1 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Caveolin PF01146.17 CBY21453.1 - 0.25 11.3 1.9 0.38 10.7 1.9 1.3 1 0 0 1 1 1 0 Caveolin DUF2810 PF10928.8 CBY21454.1 - 0.077 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) RelA_SpoT PF04607.17 CBY21454.1 - 0.13 12.5 1.9 4 7.7 1.9 2.4 1 1 0 1 1 1 0 Region found in RelA / SpoT proteins FKBP_C PF00254.28 CBY21455.1 - 3.1e-11 43.4 0.0 6.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Calx-beta PF03160.14 CBY21456.1 - 2.7e-111 364.4 34.3 9.4e-18 64.2 0.1 29.6 33 1 0 33 33 33 15 Calx-beta domain Integrin_beta PF00362.18 CBY21456.1 - 3.9e-83 278.9 0.0 6.8e-83 278.1 0.0 1.4 1 0 0 1 1 1 1 Integrin beta chain VWA domain fn3 PF00041.21 CBY21456.1 - 3.6e-23 81.7 1.0 1.1e-11 44.9 0.0 4.0 3 0 0 3 3 3 2 Fibronectin type III domain I-EGF_1 PF18372.1 CBY21456.1 - 2e-06 27.8 2.2 2e-06 27.8 2.2 3.8 3 1 0 3 3 3 1 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 CBY21456.1 - 0.00018 21.8 67.3 0.00079 19.7 12.8 5.0 4 0 0 4 4 4 3 EGF-like domain TerD PF02342.18 CBY21456.1 - 0.029 13.8 0.4 0.93 8.9 0.0 3.3 4 0 0 4 4 4 0 TerD domain MG4 PF17789.1 CBY21456.1 - 0.049 13.8 0.3 1.1 9.4 0.0 3.3 3 0 0 3 3 3 0 Macroglobulin domain MG4 fn3 PF00041.21 CBY21457.1 - 4.9e-21 74.9 3.4 3.3e-11 43.4 0.0 3.3 3 0 0 3 3 3 2 Fibronectin type III domain Calx-beta PF03160.14 CBY21457.1 - 3e-08 33.7 0.0 6.1e-07 29.5 0.0 2.8 2 0 0 2 2 2 1 Calx-beta domain Pur_ac_phosph_N PF16656.5 CBY21457.1 - 2.3 8.9 13.6 1.3 9.6 0.1 4.7 4 2 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain TRAM_LAG1_CLN8 PF03798.16 CBY21458.1 - 4.5e-33 114.7 20.4 6.9e-33 114.1 20.4 1.3 1 0 0 1 1 1 1 TLC domain TctB PF07331.11 CBY21458.1 - 0.091 13.0 7.0 0.075 13.3 1.3 2.8 2 2 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family AAA_lid_3 PF17862.1 CBY21459.1 - 3.2e-05 23.7 0.2 4.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CBY21460.1 - 0.00055 20.4 0.1 0.0006 20.2 0.1 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CBY21460.1 - 0.09 12.6 0.2 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Sec1 PF00995.23 CBY21463.1 - 8.3e-105 352.2 4.8 9.5e-105 352.0 4.8 1.0 1 0 0 1 1 1 1 Sec1 family LMBR1 PF04791.16 CBY21463.1 - 0.17 10.7 1.5 0.23 10.3 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Swi3 PF07962.12 CBY21463.1 - 0.2 11.6 1.0 0.59 10.2 1.0 1.7 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 DHR10 PF18595.1 CBY21463.1 - 0.57 10.2 5.7 2.5 8.2 6.0 1.9 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Sec1 PF00995.23 CBY21464.1 - 2.8e-78 264.6 9.1 3.2e-78 264.4 9.1 1.0 1 0 0 1 1 1 1 Sec1 family Med11 PF10280.9 CBY21465.1 - 3.3e-09 37.3 0.6 4.1e-09 37.0 0.6 1.1 1 0 0 1 1 1 1 Mediator complex protein FANCI_S4 PF14678.6 CBY21465.1 - 0.028 13.5 0.2 0.031 13.4 0.2 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 DUF5446 PF17522.2 CBY21465.1 - 0.078 13.2 0.7 0.2 11.8 0.4 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5446) DHR10 PF18595.1 CBY21465.1 - 0.13 12.4 1.7 0.19 11.8 1.5 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Transket_pyr PF02779.24 CBY21467.1 - 9.4e-43 145.9 0.0 1.3e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBY21467.1 - 7.9e-34 116.2 0.1 2.1e-33 114.9 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain LSM PF01423.22 CBY21468.1 - 7.9e-19 67.1 0.5 9.9e-19 66.8 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CBY21468.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Gemin7 PF11095.8 CBY21468.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) zf-RING_2 PF13639.6 CBY21469.1 - 1.5e-12 47.6 10.4 3.3e-12 46.5 10.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY21469.1 - 5.8e-10 38.9 9.1 1.2e-09 37.8 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CUE PF02845.16 CBY21469.1 - 1.2e-09 37.7 0.3 3.6e-09 36.1 0.1 1.9 2 0 0 2 2 2 1 CUE domain zf-RING_UBOX PF13445.6 CBY21469.1 - 5.4e-08 32.7 3.2 5.4e-08 32.7 3.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY21469.1 - 1.2e-07 31.9 8.7 7.4e-07 29.4 9.5 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY21469.1 - 3.6e-07 29.9 9.2 7.1e-07 29.0 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY21469.1 - 9.2e-07 28.6 7.9 1.9e-06 27.7 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY21469.1 - 3.4e-05 23.5 5.3 3.4e-05 23.5 5.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 CBY21469.1 - 0.00021 21.2 10.9 0.00041 20.3 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY21469.1 - 0.00028 20.7 10.2 0.00053 19.8 10.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBY21469.1 - 0.00064 19.3 12.3 0.0018 17.9 12.3 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CBY21469.1 - 0.0089 16.1 8.8 0.023 14.8 8.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CBY21469.1 - 0.094 12.9 8.0 0.19 11.9 8.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CDC24_OB3 PF17244.2 CBY21469.1 - 0.48 10.1 3.7 1 9.0 3.7 1.5 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 DUF973 PF06157.11 CBY21469.1 - 5.3 6.0 6.8 1.7 7.6 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF973) Formyl_trans_N PF00551.19 CBY21470.1 - 6.5e-16 58.6 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CBY21470.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 Formyl transferase, C-terminal domain cwf18 PF08315.12 CBY21471.1 - 1.7e-30 106.4 7.4 2.1e-30 106.1 7.4 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor AA_permease PF00324.21 CBY21472.1 - 3.4e-87 293.0 48.2 4.5e-87 292.6 48.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CBY21472.1 - 1.5e-21 76.7 54.9 2.5e-21 76.0 54.9 1.3 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CBY21472.1 - 7.7e-13 48.2 0.0 9.9e-10 38.0 0.0 2.1 2 0 0 2 2 2 2 Solute carrier family 12 CBFD_NFYB_HMF PF00808.23 CBY21473.1 - 7.8e-10 38.9 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY21473.1 - 2.5e-05 24.7 0.0 3.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY21473.1 - 0.06 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold WD40 PF00400.32 CBY21475.1 - 5.7e-11 42.8 16.1 0.015 16.1 0.0 6.8 5 2 2 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21475.1 - 5.2e-09 36.3 2.4 0.0015 18.8 0.3 5.4 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBY21475.1 - 0.0012 18.0 1.8 1.1 8.2 0.1 3.5 2 1 0 2 2 2 2 Coatomer WD associated region Mcl1_mid PF12341.8 CBY21475.1 - 0.015 14.6 0.3 0.5 9.7 0.1 2.5 2 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region ComS PF17584.2 CBY21475.1 - 0.033 13.7 0.4 0.1 12.1 0.4 1.8 1 0 0 1 1 1 0 Bacillus competence protein S Tristanin_u2 PF16638.5 CBY21475.1 - 0.12 13.2 0.2 0.48 11.3 0.1 2.1 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Laminin_G_2 PF02210.24 CBY21477.1 - 0.00013 22.6 0.0 0.065 13.8 0.0 2.7 2 1 1 3 3 3 2 Laminin G domain EGF PF00008.27 CBY21477.1 - 0.002 18.4 6.4 0.0039 17.4 6.4 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 CBY21477.1 - 0.004 17.7 4.1 0.004 17.7 4.1 2.2 2 0 0 2 2 2 1 Human growth factor-like EGF VWA PF00092.28 CBY21478.1 - 1.8e-30 106.5 3.3 2.6e-30 106.0 3.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY21478.1 - 2.5e-11 44.2 0.1 4.4e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain GST_N PF02798.20 CBY21479.1 - 4.2e-15 55.8 0.0 5.5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY21479.1 - 6.8e-12 45.5 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY21479.1 - 8.1e-12 45.4 0.1 1.1e-11 44.9 0.1 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CBY21479.1 - 0.019 15.2 0.0 0.054 13.7 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin DUF1390 PF07150.11 CBY21479.1 - 0.038 13.7 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) CAP_C PF08603.11 CBY21479.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal GST_C_3 PF14497.6 CBY21480.1 - 7.1e-07 29.3 0.0 8.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY21480.1 - 5.9e-05 23.2 0.0 7.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY21480.1 - 0.00078 19.4 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-3CxxC_2 PF17180.4 CBY21481.1 - 8.3e-12 45.7 30.0 3.7e-10 40.4 5.5 3.4 2 2 2 4 4 4 2 Zinc-binding domain AGTRAP PF06396.11 CBY21481.1 - 0.2 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) ATP19 PF11022.8 CBY21481.1 - 0.33 11.4 2.3 0.33 11.3 0.1 2.2 2 0 0 2 2 2 0 ATP synthase subunit K Trefoil PF00088.18 CBY21483.1 - 0.0029 17.5 3.7 0.0044 16.9 3.7 1.3 1 0 0 1 1 1 1 Trefoil (P-type) domain DUF2095 PF09868.9 CBY21483.1 - 0.015 15.2 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) HAD_SAK_1 PF10307.9 CBY21483.1 - 0.12 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins Homeodomain PF00046.29 CBY21484.1 - 1.7e-17 63.0 2.2 3.2e-17 62.1 2.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY21484.1 - 1.6e-05 24.7 2.5 0.00012 21.9 0.1 3.1 3 0 0 3 3 3 1 Homeobox KN domain Zn-ribbon_8 PF09723.10 CBY21484.1 - 0.34 11.1 1.9 0.64 10.2 1.9 1.4 1 0 0 1 1 1 0 Zinc ribbon domain WD40 PF00400.32 CBY21485.1 - 2e-08 34.7 2.7 0.14 13.1 0.0 4.1 3 1 1 4 4 4 3 WD domain, G-beta repeat DUF4394 PF14339.6 CBY21485.1 - 0.1 12.0 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) DUF5344 PF17279.2 CBY21486.1 - 0.0036 17.8 1.0 0.0036 17.8 1.0 2.0 1 1 1 2 2 2 1 Family of unknown function (DUF5344) AF0941-like PF14591.6 CBY21486.1 - 0.018 15.6 1.1 0.033 14.8 0.9 1.5 1 1 0 1 1 1 0 AF0941-like Prominin PF05478.11 CBY21486.1 - 0.031 12.3 2.4 0.04 11.9 2.4 1.1 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 CBY21486.1 - 0.044 13.8 6.4 0.059 13.4 3.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3198 PF11433.8 CBY21486.1 - 0.056 13.3 0.3 0.27 11.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3198) CHB_HEX PF03173.13 CBY21486.1 - 0.059 13.0 1.1 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 Putative carbohydrate binding domain UPF0242 PF06785.11 CBY21486.1 - 0.19 11.8 4.3 0.29 11.2 4.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus mCpol PF18182.1 CBY21486.1 - 0.25 11.7 2.3 0.36 11.2 0.4 2.1 2 1 0 2 2 2 0 minimal CRISPR polymerase domain Atg14 PF10186.9 CBY21486.1 - 0.25 10.4 4.6 0.3 10.1 4.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LIM PF00412.22 CBY21487.1 - 3.3e-22 78.5 28.7 1e-11 44.9 12.5 3.7 3 1 0 3 3 3 2 LIM domain T5orf172 PF10544.9 CBY21487.1 - 0.045 14.3 0.2 0.091 13.3 0.2 1.5 1 0 0 1 1 1 0 T5orf172 domain UVR PF02151.19 CBY21487.1 - 0.15 11.9 0.1 0.97 9.3 0.1 2.2 1 1 0 1 1 1 0 UvrB/uvrC motif DZR PF12773.7 CBY21487.1 - 1.1 9.3 23.3 27 4.9 5.4 3.9 1 1 2 3 3 3 0 Double zinc ribbon Acetyltransf_1 PF00583.25 CBY21488.1 - 6.9e-09 36.0 0.1 1e-08 35.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY21488.1 - 3.4e-06 27.0 0.1 7.8e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY21488.1 - 1.8e-05 24.6 0.2 4.6e-05 23.3 0.1 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 CBY21488.1 - 0.00052 20.4 0.2 0.0067 16.8 0.2 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain RNA_pol_Rpb5_C PF01191.19 CBY21489.1 - 0.00044 20.1 1.7 0.067 13.1 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb5, C-terminal domain Myb_DNA-binding PF00249.31 CBY21489.1 - 0.048 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBY21489.1 - 0.14 12.1 2.9 0.31 11.0 1.8 2.2 2 0 0 2 2 2 0 Myb DNA-binding like ELM2 PF01448.24 CBY21489.1 - 0.22 12.3 0.0 0.22 12.3 0.0 2.7 2 1 0 2 2 2 0 ELM2 domain SH3_9 PF14604.6 CBY21490.1 - 1.4e-43 146.5 0.6 2.1e-14 53.1 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 CBY21490.1 - 2.2e-37 126.4 4.4 1.7e-12 46.8 0.1 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBY21490.1 - 3.4e-30 103.5 0.1 2.7e-12 46.2 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain betaPIX_CC PF16523.5 CBY21490.1 - 0.085 12.7 3.0 0.18 11.7 3.0 1.5 1 0 0 1 1 1 0 betaPIX coiled coil NUFIP1 PF10453.9 CBY21491.1 - 2.7e-15 55.9 9.0 2.7e-15 55.9 9.0 2.8 3 1 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 CBY21491.1 - 0.00025 21.2 2.4 0.00073 19.8 2.4 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Cwf_Cwc_15 PF04889.12 CBY21491.1 - 0.0094 15.7 20.6 0.014 15.1 20.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-met PF12874.7 CBY21491.1 - 0.013 15.9 2.7 0.013 15.9 0.3 2.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 CBY21491.1 - 0.066 12.8 0.2 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Presenilin PF01080.17 CBY21491.1 - 1.1 8.0 7.7 1.4 7.6 7.7 1.3 1 0 0 1 1 1 0 Presenilin zf-C2H2_4 PF13894.6 CBY21491.1 - 9.7 7.3 6.2 2.6 9.1 0.2 2.9 2 1 1 3 3 3 0 C2H2-type zinc finger TK PF00265.18 CBY21492.1 - 1.1e-63 214.3 0.3 1.4e-63 214.0 0.3 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_16 PF13191.6 CBY21492.1 - 0.018 15.5 0.0 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 CBY21492.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY21492.1 - 0.088 12.6 0.1 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_transf_21 PF13506.6 CBY21493.1 - 1.6e-41 141.7 0.0 2.3e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CBY21493.1 - 4.3e-23 82.4 0.0 6.6e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY21493.1 - 3.1e-13 50.1 2.4 4.8e-13 49.5 2.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CBY21493.1 - 2.9e-06 27.2 0.0 8.5e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 MIF4G PF02854.19 CBY21494.1 - 5.9e-25 88.1 6.0 8.7e-25 87.6 4.3 2.2 2 1 0 2 2 2 1 MIF4G domain MIF4G PF02854.19 CBY21495.1 - 4e-05 23.3 0.2 6.4e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 MIF4G domain DUF5570 PF17731.1 CBY21496.1 - 0.098 12.8 0.2 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5570) zf-RanBP PF00641.18 CBY21496.1 - 0.098 12.0 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others NDUF_B6 PF09782.9 CBY21497.1 - 0.00081 19.6 0.4 0.0019 18.3 0.4 1.6 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit NAD_binding_2 PF03446.15 CBY21498.1 - 4.6e-40 137.4 0.0 9e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBY21498.1 - 5.1e-25 88.1 0.4 8.2e-25 87.4 0.4 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.17 CBY21498.1 - 1.2e-10 41.6 0.0 2.7e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.17 CBY21498.1 - 6e-09 36.4 0.0 1.6e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CBY21498.1 - 8e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CBY21498.1 - 3.2e-05 23.6 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CBY21498.1 - 4.3e-05 23.6 0.0 7.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 CBY21498.1 - 0.0011 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 CBY21498.1 - 0.034 14.1 0.6 0.053 13.5 0.1 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_N PF05222.15 CBY21498.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain 3HCDH_N PF02737.18 CBY21498.1 - 0.1 12.5 1.2 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CBY21498.1 - 0.17 11.4 0.6 7.4 6.1 0.0 2.6 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Striatin PF08232.12 CBY21498.1 - 0.45 11.1 3.7 0.73 10.4 3.7 1.2 1 0 0 1 1 1 0 Striatin family EF-hand_7 PF13499.6 CBY21499.1 - 1.2e-09 38.4 0.1 5.6e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CBY21499.1 - 1.5e-06 28.5 0.0 0.043 14.1 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 CBY21499.1 - 1.8e-06 27.4 0.1 0.0061 16.4 0.0 3.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBY21499.1 - 0.00018 20.8 0.2 0.016 14.7 0.0 2.8 3 0 0 3 3 3 1 EF hand EFhand_Ca_insen PF08726.10 CBY21499.1 - 0.031 14.4 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF2294 PF10057.9 CBY21499.1 - 0.06 13.5 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) Mt_ATP-synt_D PF05873.12 CBY21500.1 - 4.4e-30 104.6 0.3 6.4e-30 104.0 0.3 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) FerA PF08165.11 CBY21500.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 FerA (NUC095) domain NTF2 PF02136.20 CBY21501.1 - 9.2e-15 55.3 0.1 1.1e-14 55.0 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain IPK PF03770.16 CBY21501.1 - 0.012 15.5 1.6 0.013 15.4 0.7 1.5 1 1 1 2 2 2 0 Inositol polyphosphate kinase DUF2524 PF10732.9 CBY21501.1 - 0.39 11.0 4.0 0.18 12.2 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Hormone_recep PF00104.30 CBY21502.1 - 5.2e-31 107.9 0.1 7.8e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CBY21502.1 - 2e-28 98.7 18.5 4.2e-28 97.6 18.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) SH3_13 PF18335.1 CBY21504.1 - 0.015 15.1 0.8 0.043 13.6 0.1 2.0 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain Y_phosphatase PF00102.27 CBY21505.1 - 0.00015 21.4 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_M PF00373.18 CBY21506.1 - 1.6e-13 51.1 0.2 1.6e-13 51.1 0.2 2.3 3 0 0 3 3 3 1 FERM central domain FERM_N PF09379.10 CBY21506.1 - 2.4e-10 40.2 0.0 5.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 CBY21506.1 - 0.0022 18.4 0.0 0.0056 17.0 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Ntox15 PF15604.6 CBY21506.1 - 0.0032 17.6 2.1 0.059 13.5 0.3 2.6 3 0 0 3 3 3 1 Novel toxin 15 Asp PF00026.23 CBY21507.1 - 4.8e-119 397.5 0.2 5.6e-119 397.2 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CBY21507.1 - 8.1e-14 52.2 0.4 8.5e-13 48.9 0.4 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CBY21507.1 - 2.4e-05 24.2 0.0 0.00016 21.5 0.0 2.1 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CBY21507.1 - 0.0057 17.3 0.0 4.2 8.1 0.0 2.9 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 CBY21507.1 - 0.015 15.9 0.0 5 7.8 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RasGEF PF00617.19 CBY21508.1 - 1.6e-35 122.9 0.4 2.8e-35 122.1 0.1 1.6 2 0 0 2 2 2 1 RasGEF domain HEAT_2 PF13646.6 CBY21509.1 - 0.0012 19.1 0.0 0.0049 17.2 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 CBY21509.1 - 0.044 14.3 0.0 0.97 10.0 0.0 2.7 2 1 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 CBY21509.1 - 0.048 13.9 0.0 21 5.7 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Vac14_Fab1_bd PF12755.7 CBY21509.1 - 0.05 14.2 0.1 5.6 7.6 0.0 2.4 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Pkinase PF00069.25 CBY21510.1 - 3.3e-78 262.7 0.0 6.3e-78 261.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21510.1 - 1.5e-45 155.5 0.0 6.4e-45 153.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY21510.1 - 3.5e-07 29.8 0.0 1.1e-05 24.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBY21510.1 - 4e-05 22.6 1.2 0.00011 21.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 CBY21510.1 - 0.00034 20.8 0.0 0.11 12.6 0.0 3.3 3 0 0 3 3 3 1 ABC1 family Haspin_kinase PF12330.8 CBY21510.1 - 0.001 18.1 0.1 0.001 18.1 0.1 2.6 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 CBY21510.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CBY21510.1 - 0.027 14.0 0.1 0.083 12.4 0.1 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 CBY21510.1 - 0.035 13.4 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dynein_AAA_lid PF17852.1 CBY21510.1 - 0.043 13.9 0.0 0.21 11.7 0.0 2.1 1 1 0 1 1 1 0 Dynein heavy chain AAA lid domain FTA2 PF13095.6 CBY21510.1 - 0.19 11.3 2.0 0.76 9.4 0.1 2.5 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Lectin_C PF00059.21 CBY21511.1 - 1.1e-05 26.1 1.0 1.5e-05 25.7 1.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain 3-alpha PF03475.14 CBY21512.1 - 0.14 12.0 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 3-alpha domain Carb_kinase PF01256.17 CBY21513.1 - 5e-55 186.6 0.0 5.7e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CBY21513.1 - 0.023 14.1 0.0 0.064 12.6 0.0 1.8 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase HK PF02110.15 CBY21513.1 - 0.067 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family CBAH PF02275.18 CBY21514.1 - 4.4e-14 52.8 0.0 1.3e-12 48.0 0.0 2.1 2 0 0 2 2 2 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.6 CBY21514.1 - 1.4e-13 50.9 0.4 4e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HP_OMP PF01856.17 CBY21514.1 - 0.093 12.8 0.3 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Helicobacter outer membrane protein CKS PF01111.19 CBY21515.1 - 7.7e-34 115.8 2.5 8.6e-34 115.6 2.5 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Hepar_II_III_N PF16889.5 CBY21515.1 - 0.048 12.9 1.1 0.048 12.9 1.1 1.0 1 0 0 1 1 1 0 Heparinase II/III N-terminus Kinesin PF00225.23 CBY21516.1 - 9.3e-85 284.5 0.0 9.3e-85 284.5 0.0 2.5 2 1 0 2 2 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY21516.1 - 2.2e-21 76.4 0.1 1e-18 67.7 0.0 3.3 2 0 0 2 2 2 1 Microtubule binding TPR_MLP1_2 PF07926.12 CBY21516.1 - 0.00036 20.6 83.7 0.4 10.8 0.1 7.8 3 2 5 8 8 8 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CBY21516.1 - 0.0014 17.6 85.5 0.018 13.9 13.7 5.0 2 2 2 4 4 4 3 Spc7 kinetochore protein Atg14 PF10186.9 CBY21516.1 - 0.003 16.7 68.5 0.16 11.1 6.4 4.8 1 1 2 4 4 4 3 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 CBY21516.1 - 0.0059 17.0 30.7 0.64 10.5 1.2 7.1 4 1 2 6 6 6 2 Nucleopolyhedrovirus P10 protein BST2 PF16716.5 CBY21516.1 - 0.014 16.0 2.5 0.014 16.0 2.5 8.9 5 4 3 8 8 8 0 Bone marrow stromal antigen 2 Spectrin PF00435.21 CBY21516.1 - 0.014 15.9 2.4 0.014 15.9 2.4 7.3 5 3 2 7 7 7 0 Spectrin repeat DUF4407 PF14362.6 CBY21516.1 - 0.028 13.8 49.7 1.8 7.9 9.0 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 CBY21516.1 - 0.066 13.4 73.4 0.035 14.3 15.3 5.4 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 CBY21516.1 - 0.66 9.8 93.0 0.014 15.2 22.0 5.3 3 2 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 CBY21516.1 - 0.8 7.8 86.4 0.12 10.4 33.6 3.4 2 1 2 4 4 4 0 HOOK protein CENP-F_leu_zip PF10473.9 CBY21516.1 - 3.2 7.8 96.3 0.072 13.1 12.2 7.5 3 2 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 CBY21516.1 - 5.7 7.0 81.6 2.6 8.1 10.2 7.6 2 2 6 8 8 8 0 Afadin- and alpha -actinin-Binding AAA_16 PF13191.6 CBY21516.1 - 8.6 6.7 6.9 2.9 8.2 0.0 3.3 2 1 0 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 CBY21516.1 - 9.8 3.5 71.1 0.11 10.0 46.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Ribonuc_2-5A PF06479.12 CBY21517.1 - 1.6e-06 28.3 5.8 4.4e-06 26.9 0.4 2.5 1 1 1 2 2 2 2 Ribonuclease 2-5A INCENP_ARK-bind PF03941.15 CBY21517.1 - 0.092 12.7 0.2 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region STI1 PF17830.1 CBY21517.1 - 0.12 12.4 0.8 22 5.1 0.2 3.0 2 1 1 3 3 3 0 STI1 domain Flavoprotein PF02441.19 CBY21519.1 - 1.1e-16 61.0 0.0 1.5e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein DUF4661 PF15576.6 CBY21519.1 - 0.024 14.6 0.6 0.033 14.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) TCR_zetazeta PF11628.8 CBY21520.1 - 0.05 13.3 0.7 0.086 12.5 0.7 1.3 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain MFS_2 PF13347.6 CBY21520.1 - 0.15 10.6 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein MRG PF05712.13 CBY21521.1 - 3.4e-41 140.7 1.1 3.4e-41 140.7 1.1 1.7 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 CBY21521.1 - 3.8e-09 36.3 0.2 8.2e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF4537 PF15057.6 CBY21521.1 - 0.094 12.7 0.1 0.9 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Cast PF10174.9 CBY21522.1 - 9.8e-35 120.0 72.6 1.4e-17 63.3 47.8 4.3 1 1 2 3 3 3 3 RIM-binding protein of the cytomatrix active zone NPV_P10 PF05531.12 CBY21522.1 - 3.7 8.1 13.6 6.4 7.3 0.0 5.7 5 1 2 7 7 7 0 Nucleopolyhedrovirus P10 protein PUB PF09409.10 CBY21523.1 - 3.5e-17 62.1 0.1 9.7e-17 60.7 0.1 1.8 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 CBY21523.1 - 5.5e-05 23.3 0.1 0.00016 21.8 0.1 1.8 1 1 0 1 1 1 1 UBX domain PRP21_like_P PF12230.8 CBY21523.1 - 0.0014 18.5 1.3 0.002 18.0 0.2 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein DUF4857 PF16149.5 CBY21523.1 - 0.03 13.6 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4857) Peptidase_S8 PF00082.22 CBY21523.1 - 0.12 11.6 1.4 0.21 10.8 1.4 1.3 1 0 0 1 1 1 0 Subtilase family RF-1 PF00472.20 CBY21523.1 - 0.46 10.4 2.9 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 RF-1 domain Med30 PF11315.8 CBY21524.1 - 6.5e-08 32.9 4.5 8.4e-08 32.5 4.5 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 RNaseH_like PF04308.12 CBY21524.1 - 0.14 12.1 0.4 0.36 10.7 0.2 1.7 2 0 0 2 2 2 0 Ribonuclease H-like Med30 PF11315.8 CBY21525.1 - 2.5e-41 141.3 9.4 4e-41 140.7 9.4 1.3 1 0 0 1 1 1 1 Mediator complex subunit 30 Hrs_helical PF12210.8 CBY21525.1 - 0.013 16.1 2.2 0.044 14.3 2.0 2.1 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TerB_N PF13208.6 CBY21526.1 - 0.01 15.6 0.2 0.02 14.6 0.2 1.5 2 0 0 2 2 2 0 TerB N-terminal domain Ribosomal_L44 PF00935.19 CBY21527.1 - 6.2e-34 116.3 12.4 8.7e-34 115.8 12.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_S27e PF01667.17 CBY21528.1 - 3.6e-23 81.0 5.4 4.5e-23 80.7 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-TAZ PF02135.16 CBY21528.1 - 0.1 13.0 4.9 0.16 12.4 4.9 1.4 1 1 0 1 1 1 0 TAZ zinc finger SGS PF05002.15 CBY21529.1 - 1.1e-34 118.4 6.1 1.1e-34 118.4 6.1 1.9 2 0 0 2 2 2 1 SGS domain CS PF04969.16 CBY21529.1 - 2.1e-09 38.3 0.3 4.5e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 CS domain AsiA PF09010.10 CBY21529.1 - 0.04 14.0 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Anti-Sigma Factor A DUF2057 PF09829.9 CBY21529.1 - 0.068 13.3 5.5 0.041 14.0 4.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) W_rich_C PF07483.11 CBY21529.1 - 0.2 11.9 3.9 0.29 11.3 0.2 2.7 3 1 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain Hid1 PF12722.7 CBY21529.1 - 0.22 9.6 4.4 0.25 9.4 4.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAP2 PF01569.21 CBY21530.1 - 7e-14 51.8 3.0 1.7e-13 50.5 3.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CBY21530.1 - 0.00096 18.9 11.3 0.031 14.0 11.3 2.4 1 1 0 1 1 1 1 PAP2 superfamily Choline_transpo PF04515.12 CBY21533.1 - 2.5e-96 322.7 35.0 2.5e-96 322.7 35.0 2.6 3 0 0 3 3 3 1 Plasma-membrane choline transporter TMEM192 PF14802.6 CBY21533.1 - 2.1e-05 23.8 2.7 2.1e-05 23.8 2.7 2.0 2 0 0 2 2 2 1 TMEM192 family Astacin PF01400.24 CBY21534.1 - 3.9e-22 78.8 2.0 2.3e-21 76.3 0.9 2.3 1 1 1 2 2 2 1 Astacin (Peptidase family M12A) Trypsin PF00089.26 CBY21536.1 - 1.5e-55 188.5 2.8 1.1e-52 179.1 0.1 2.4 2 0 0 2 2 2 2 Trypsin TSP_1 PF00090.19 CBY21536.1 - 8.8e-31 105.9 73.3 5.2e-08 33.0 3.6 7.2 6 0 0 6 6 6 6 Thrombospondin type 1 domain CUB PF00431.20 CBY21536.1 - 3.5e-25 88.5 0.0 2.6e-11 43.8 0.0 3.4 3 0 0 3 3 3 2 CUB domain Pentaxin PF00354.17 CBY21536.1 - 7.5e-12 45.3 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 CBY21536.1 - 4.8e-05 23.5 0.1 0.00054 20.1 0.0 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Kelch_6 PF13964.6 CBY21538.1 - 3.2e-11 43.1 0.5 2.9e-06 27.3 0.0 4.3 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CBY21538.1 - 1.8e-05 24.9 0.1 0.00071 19.8 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY21538.1 - 6e-05 22.9 0.3 0.046 13.7 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY21538.1 - 0.00035 20.5 0.4 0.3 11.1 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY21538.1 - 0.00048 20.0 5.7 0.85 9.7 0.0 4.7 4 1 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 CBY21538.1 - 0.00055 19.5 1.5 0.058 13.0 0.0 3.8 3 1 0 3 3 3 1 Kelch motif Ion_trans PF00520.31 CBY21539.1 - 8.2e-08 31.8 23.0 8.2e-08 31.8 23.0 1.5 2 0 0 2 2 2 1 Ion transport protein CitMHS PF03600.16 CBY21539.1 - 0.0077 15.5 5.3 0.024 13.9 5.4 1.7 1 1 0 1 1 1 1 Citrate transporter Lact-deh-memb PF09330.11 CBY21539.1 - 0.048 13.0 0.1 0.073 12.4 0.1 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Fib_alpha PF08702.10 CBY21539.1 - 2.4 8.3 6.8 5.5 7.2 6.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.7 CBY21540.1 - 2.4e-10 40.9 0.0 1.1e-07 32.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY21540.1 - 4e-07 29.8 0.1 0.011 16.2 0.0 4.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 CBY21540.1 - 1.5e-06 28.7 0.1 0.0023 18.4 0.0 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY21540.1 - 1.8e-06 28.1 0.0 0.00029 21.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY21540.1 - 0.0026 18.1 0.0 2.3 8.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat STE PF02200.16 CBY21540.1 - 0.012 16.1 1.4 2.1 8.8 0.4 2.4 1 1 1 2 2 2 0 STE like transcription factor AMP-binding PF00501.28 CBY21541.1 - 2.4e-43 148.3 4.1 6.5e-27 94.2 0.0 4.7 5 0 0 5 5 5 4 AMP-binding enzyme Cyclin_N PF00134.23 CBY21542.1 - 5.3e-23 81.1 0.7 9.7e-23 80.3 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain OTCace_N PF02729.21 CBY21542.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Cyclin_C PF02984.19 CBY21542.1 - 0.71 10.0 3.9 1.1 9.3 1.2 2.4 2 1 1 3 3 3 0 Cyclin, C-terminal domain BAH PF01426.18 CBY21544.1 - 5.2e-05 23.1 0.2 0.00038 20.3 0.2 2.3 1 1 0 1 1 1 1 BAH domain PMSR PF01625.21 CBY21547.1 - 1.1e-61 207.5 0.7 1.3e-61 207.3 0.7 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CAP_N PF01213.19 CBY21548.1 - 4.6e-101 338.5 0.1 7.2e-101 337.8 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CBY21548.1 - 1.8e-54 183.6 8.0 2.4e-54 183.2 8.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CBY21548.1 - 0.063 13.0 2.4 0.11 12.3 2.4 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C Totivirus_coat PF05518.11 CBY21548.1 - 5 5.0 6.5 7.2 4.5 6.5 1.1 1 0 0 1 1 1 0 Totivirus coat protein Mob_synth_C PF06463.13 CBY21549.1 - 1.2e-34 119.1 0.0 2e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 CBY21549.1 - 6.5e-26 91.7 0.0 1.7e-25 90.3 0.0 1.7 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 CBY21549.1 - 8.6e-08 32.6 0.0 2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 CBY21549.1 - 4.8e-07 29.9 0.0 9.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Dymeclin PF09742.9 CBY21551.1 - 1.6e-87 294.4 14.5 1.9e-87 294.2 14.5 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CBY21551.1 - 2.8e-14 52.3 22.3 8.2e-13 47.4 9.1 4.0 4 0 0 4 4 4 4 High-temperature-induced dauer-formation protein ATP-synt PF00231.19 CBY21551.1 - 0.031 14.0 0.4 0.28 10.9 0.0 2.4 2 1 0 2 2 2 0 ATP synthase NLRC4_HD PF17889.1 CBY21551.1 - 0.038 14.3 1.2 0.16 12.3 0.2 2.7 2 1 0 2 2 2 0 NLRC4 helical domain HdeA PF06411.11 CBY21551.1 - 0.083 13.1 0.1 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 HdeA/HdeB family EST1_DNA_bind PF10373.9 CBY21552.1 - 9.9e-22 77.7 2.9 2.4e-15 56.8 0.2 2.6 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain MitMem_reg PF13012.6 CBY21552.1 - 4.3e-17 62.6 0.2 8.3e-16 58.4 0.1 2.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function EST1 PF10374.9 CBY21552.1 - 1.8e-13 51.3 0.3 1.8e-13 51.3 0.3 2.7 2 1 0 2 2 2 1 Telomerase activating protein Est1 JAB PF01398.21 CBY21552.1 - 2e-13 50.4 0.0 9.2e-13 48.2 0.0 2.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3192 PF11399.8 CBY21552.1 - 0.76 9.8 3.4 4.6 7.2 3.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) FmiP_Thoc5 PF09766.9 CBY21553.1 - 3.5e-44 151.6 3.4 3.5e-44 151.6 3.4 2.5 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 RWD PF05773.22 CBY21553.1 - 0.042 14.2 2.5 0.23 11.8 2.5 2.4 1 1 0 1 1 1 0 RWD domain FAA_hydrolase_N PF09298.11 CBY21553.1 - 0.098 12.8 0.2 0.41 10.9 0.2 2.1 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal HTH_40 PF14493.6 CBY21553.1 - 1.4 9.4 8.6 0.12 12.9 0.6 3.2 4 0 0 4 4 4 0 Helix-turn-helix domain Gtr1_RagA PF04670.12 CBY21554.1 - 3e-81 272.2 1.3 4.3e-81 271.7 1.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CBY21554.1 - 4.7e-09 35.9 0.4 8e-09 35.2 0.4 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY21554.1 - 6.2e-08 32.9 0.8 2.6e-07 30.9 0.0 2.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY21554.1 - 1.7e-06 27.7 0.6 2.6e-06 27.1 0.2 1.6 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 CBY21554.1 - 2.7e-06 27.4 0.0 5.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBY21554.1 - 0.0018 17.7 0.4 0.0091 15.4 0.4 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY21554.1 - 0.0045 16.5 0.1 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY21554.1 - 0.0082 16.1 1.7 0.51 10.2 0.1 2.5 2 1 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 CBY21554.1 - 0.031 14.0 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CBY21554.1 - 0.036 14.6 0.2 0.11 13.0 0.0 1.9 2 1 0 2 2 2 0 ABC transporter ATP-grasp_2 PF08442.10 CBY21555.1 - 5e-62 209.0 0.3 7e-62 208.6 0.3 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CBY21555.1 - 5.6e-23 81.4 0.7 5.6e-23 81.4 0.7 1.6 2 0 0 2 2 2 1 CoA-ligase His_Phos_2 PF00328.22 CBY21556.1 - 7.3e-25 88.1 0.0 1.4e-24 87.2 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) VWA_2 PF13519.6 CBY21557.1 - 5.6e-17 62.3 0.3 5.2e-16 59.2 0.1 2.6 3 0 0 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 CBY21557.1 - 9.5e-08 31.5 13.8 0.00025 20.8 0.9 4.1 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 CBY21557.1 - 5.2e-07 29.7 0.3 8.9e-07 28.9 0.3 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 CBY21557.1 - 2.4e-06 27.9 0.5 4.1e-06 27.1 0.5 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain RAP80_UIM PF18282.1 CBY21557.1 - 0.002 17.8 4.0 0.002 17.8 4.0 3.4 2 1 0 2 2 2 1 RAP80 N-terminal ubiquitin interaction motif HNOBA PF07701.14 CBY21557.1 - 0.037 13.5 0.1 0.037 13.5 0.1 1.7 2 0 0 2 2 2 0 Heme NO binding associated Herpes_UL17 PF04559.12 CBY21557.1 - 0.41 9.4 5.5 7.9 5.2 4.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL17 protein Methyltransf_31 PF13847.6 CBY21558.1 - 1.3e-09 38.0 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY21558.1 - 4e-06 26.8 0.0 7.8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY21558.1 - 6.1e-06 26.9 0.0 1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY21558.1 - 7.1e-05 23.5 0.0 0.00012 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY21558.1 - 0.00014 22.5 0.0 0.00025 21.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY21558.1 - 0.0021 17.6 0.0 0.0049 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CBY21558.1 - 0.017 14.5 0.0 0.019 14.4 0.0 1.2 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 CBY21558.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FeS_assembly_P PF01883.19 CBY21559.1 - 7.5e-16 58.1 0.0 3e-15 56.2 0.0 2.0 1 1 1 2 2 2 1 Iron-sulfur cluster assembly protein Tubulin PF00091.25 CBY21560.1 - 1e-68 231.4 0.1 1.9e-68 230.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY21560.1 - 2e-29 102.3 0.0 3.7e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY21560.1 - 1.4e-05 25.4 0.0 3.4e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBY21560.1 - 0.039 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 CBY21560.1 - 0.055 12.7 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Tubulin like FeS_assembly_P PF01883.19 CBY21562.1 - 7.5e-16 58.1 0.0 3e-15 56.2 0.0 2.0 1 1 1 2 2 2 1 Iron-sulfur cluster assembly protein Tubulin PF00091.25 CBY21563.1 - 1.5e-68 230.9 0.0 2.7e-68 230.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY21563.1 - 1.9e-35 121.7 0.1 3.7e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY21563.1 - 1.7e-05 25.1 0.0 4.5e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CBY21563.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like EF-hand_1 PF00036.32 CBY21565.1 - 1.2e-43 143.5 9.5 4.8e-10 38.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY21565.1 - 7.8e-37 125.6 2.3 5.6e-19 68.4 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY21565.1 - 8.6e-35 118.4 10.0 1.9e-15 56.4 0.4 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBY21565.1 - 3.9e-31 104.3 4.9 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBY21565.1 - 6.2e-28 95.0 6.4 1.2e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBY21565.1 - 5.5e-16 58.7 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBY21565.1 - 1.2e-10 41.3 0.3 3e-05 23.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY21565.1 - 4e-08 33.6 0.0 0.004 17.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBY21565.1 - 1.2e-06 29.3 0.0 0.00049 20.9 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CBY21565.1 - 1.2e-05 25.2 0.0 0.042 13.9 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CBY21565.1 - 1.5e-05 25.0 0.8 0.0001 22.4 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 CBY21565.1 - 0.00035 20.3 2.0 0.00038 20.2 2.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Dockerin_1 PF00404.18 CBY21565.1 - 0.00049 20.2 4.7 0.075 13.2 0.4 3.0 1 1 2 3 3 3 2 Dockerin type I domain DUF3349 PF11829.8 CBY21565.1 - 0.00082 20.1 0.4 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CBY21565.1 - 0.0011 19.0 0.7 0.53 10.2 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein DUF4497 PF14924.6 CBY21565.1 - 0.0017 18.8 0.0 0.9 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 CBY21565.1 - 0.0028 17.6 0.4 0.49 10.4 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 CBY21565.1 - 0.0032 17.8 0.7 1.7 9.0 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF5580 PF17743.1 CBY21565.1 - 0.0095 14.5 0.0 0.0095 14.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Poly_export PF02563.16 CBY21565.1 - 0.011 15.9 0.1 0.53 10.6 0.0 3.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 CBY21565.1 - 0.013 15.4 0.5 0.8 9.6 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 CBY21565.1 - 0.025 14.9 0.1 9.1 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain DUF2267 PF10025.9 CBY21565.1 - 0.026 14.8 0.0 0.099 12.9 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Fe_hyd_lg_C PF02906.14 CBY21565.1 - 0.046 13.4 0.7 0.19 11.4 0.7 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MotA_activ PF09114.10 CBY21565.1 - 0.058 13.5 0.3 1.1 9.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 CBY21565.1 - 0.074 12.2 0.2 7.5 5.6 0.1 2.4 1 1 0 2 2 2 0 Cache domain TetR_C_7 PF14246.6 CBY21565.1 - 0.085 12.9 0.1 7.3 6.7 0.0 2.8 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Spore_III_AB PF09548.10 CBY21565.1 - 0.12 12.5 0.3 0.25 11.4 0.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RuvA_C PF07499.13 CBY21565.1 - 0.13 12.7 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain SapB_1 PF05184.15 CBY21565.1 - 0.23 11.5 1.2 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 CMD PF02627.20 CBY21565.1 - 0.31 11.1 1.1 6.9 6.8 0.0 2.8 2 2 1 3 3 3 0 Carboxymuconolactone decarboxylase family HLH PF00010.26 CBY21566.1 - 5.6e-15 55.0 0.1 9.8e-15 54.3 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BLI1 PF17324.2 CBY21566.1 - 0.021 15.5 5.6 0.58 10.8 0.3 2.3 1 1 1 2 2 2 0 BLOC-1 interactor 1 Endotoxin_N PF03945.14 CBY21566.1 - 0.097 12.4 1.9 0.13 11.9 1.9 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain SVIP PF15811.5 CBY21566.1 - 0.1 13.1 0.2 0.1 13.1 0.2 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein HD_3 PF13023.6 CBY21567.1 - 1.7e-09 37.8 0.4 2.3e-09 37.4 0.3 1.2 1 1 0 1 1 1 1 HD domain LcrG PF07216.12 CBY21567.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 LcrG protein NCBP3 PF10309.9 CBY21568.1 - 1.8e-09 37.3 0.0 3.8e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Ribosomal_60s PF00428.19 CBY21568.1 - 7.5 7.2 8.2 2.9 8.5 0.2 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein Trypsin PF00089.26 CBY21569.1 - 0.00022 21.1 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin TGT PF01702.18 CBY21570.1 - 1e-126 422.8 0.0 1.3e-126 422.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase COG7 PF10191.9 CBY21571.1 - 4.3e-109 365.9 13.3 7.5e-109 365.1 13.3 1.4 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) DUF5078 PF16877.5 CBY21571.1 - 0.053 14.0 0.2 0.15 12.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) Mit_KHE1 PF10173.9 CBY21571.1 - 0.062 13.4 2.9 0.12 12.5 2.9 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Baculo_PEP_N PF04512.12 CBY21571.1 - 0.084 13.2 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Rx_N PF18052.1 CBY21571.1 - 0.092 13.0 3.9 0.18 12.1 1.7 2.7 2 1 1 3 3 3 0 Rx N-terminal domain BLOC1_2 PF10046.9 CBY21571.1 - 0.16 12.3 7.4 0.1 12.9 2.8 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tup_N PF08581.10 CBY21571.1 - 0.63 10.4 5.8 0.19 12.0 1.6 2.4 2 1 0 2 2 2 0 Tup N-terminal Tropomyosin_1 PF12718.7 CBY21571.1 - 5.8 7.1 14.9 4.3 7.5 10.9 2.7 1 1 1 2 2 2 0 Tropomyosin like CREPT PF16566.5 CBY21571.1 - 6.8 6.9 9.1 5.4 7.2 3.9 3.3 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour WD40 PF00400.32 CBY21572.1 - 1.1e-18 67.2 18.1 4.4e-07 30.5 0.2 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CBY21572.1 - 1.1e-11 44.7 0.0 1.5e-10 41.1 0.0 2.6 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CBY21572.1 - 3.1e-07 30.6 3.4 0.0007 19.8 0.1 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain bZIP_2 PF07716.15 CBY21573.1 - 5.3e-11 42.4 6.0 5.3e-11 42.4 6.0 2.7 1 1 1 3 3 3 1 Basic region leucine zipper Spc7 PF08317.11 CBY21573.1 - 1.3 7.9 16.8 1.8 7.4 16.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0564 PF10595.9 CBY21574.1 - 1.9e-21 76.6 46.7 1.9e-21 76.6 46.7 3.1 2 1 0 2 2 2 1 Uncharacterised protein family UPF0564 DnaJ PF00226.31 CBY21577.1 - 1.6e-06 28.1 0.6 6.1e-06 26.3 0.6 2.1 1 1 0 1 1 1 1 DnaJ domain DUF1515 PF07439.11 CBY21577.1 - 0.0056 16.7 0.2 0.017 15.1 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1515) LapA_dom PF06305.11 CBY21577.1 - 0.02 14.7 0.1 0.064 13.1 0.1 1.9 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Microtub_bind PF13931.6 CBY21577.1 - 0.21 12.0 9.7 0.61 10.5 9.7 1.8 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding Ank_2 PF12796.7 CBY21578.1 - 6.3e-21 74.8 0.0 2.4e-12 47.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY21578.1 - 3.5e-16 59.3 0.0 5.4e-06 26.8 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY21578.1 - 2.9e-14 52.9 0.6 1.5e-06 28.3 0.1 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY21578.1 - 1.4e-13 49.7 0.0 0.014 15.9 0.0 4.9 4 1 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CBY21578.1 - 5.1e-13 48.8 0.3 0.0013 19.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat CUB PF00431.20 CBY21579.1 - 3.6e-21 75.6 0.0 5.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 CUB domain SARAF PF06682.12 CBY21579.1 - 0.0017 18.1 1.6 0.0021 17.8 0.0 1.8 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4199 PF13858.6 CBY21579.1 - 0.19 12.1 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) FliX PF10768.9 CBY21579.1 - 4.2 7.9 7.8 0.4 11.2 3.3 1.5 2 0 0 2 2 2 0 Class II flagellar assembly regulator WD40 PF00400.32 CBY21580.1 - 0.0031 18.3 8.4 6.8 7.7 0.7 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat LSM PF01423.22 CBY21582.1 - 4.8e-21 74.2 1.0 5.4e-21 74.0 1.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY21582.1 - 0.083 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 CBY21582.1 - 0.083 13.0 0.2 0.12 12.4 0.2 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain UbiA PF01040.18 CBY21583.1 - 2.1e-05 24.0 6.4 0.00021 20.7 2.8 2.4 1 1 1 2 2 2 1 UbiA prenyltransferase family UbiA PF01040.18 CBY21584.1 - 4.2e-18 65.6 0.1 6.1e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosomal_S10 PF00338.22 CBY21585.1 - 0.016 15.4 0.0 0.097 12.9 0.0 2.2 1 1 0 1 1 1 0 Ribosomal protein S10p/S20e Mito_carr PF00153.27 CBY21586.1 - 3.1e-50 168.1 0.5 1.6e-22 79.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydrolase PF00702.26 CBY21589.1 - 1.6e-11 44.9 2.3 1.3e-07 32.2 0.1 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY21589.1 - 1.9e-05 24.6 0.1 0.00041 20.2 0.0 2.6 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2691 PF10903.8 CBY21589.1 - 0.0051 16.7 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2691) HAD PF12710.7 CBY21589.1 - 0.028 14.8 0.0 4.1 7.8 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Lectin_C PF00059.21 CBY21590.1 - 8.9e-37 126.1 22.6 2.2e-17 63.8 5.1 4.0 3 1 0 3 3 3 3 Lectin C-type domain Ogr_Delta PF04606.12 CBY21595.1 - 0.66 10.0 3.8 1.1 9.3 0.4 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger BCAS2 PF05700.11 CBY21596.1 - 0.4 10.3 5.3 1.5 8.4 4.9 1.8 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Glyco_hydro_30 PF02055.16 CBY21597.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain Endonuc-dimeris PF09124.10 CBY21597.1 - 0.061 13.5 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation RNA_pol_Rpb5_C PF01191.19 CBY21598.1 - 5.5e-34 115.9 0.1 1.2e-33 114.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CBY21598.1 - 1.1e-30 106.0 0.1 2.4e-30 105.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain ecTbetaR2 PF08917.10 CBY21598.1 - 0.05 13.6 0.0 0.09 12.7 0.0 1.5 1 1 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain Cnl2_NKP2 PF09447.10 CBY21598.1 - 0.076 13.2 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Endonuclease_NS PF01223.23 CBY21599.1 - 3.5e-08 33.6 0.2 5.9e-08 32.8 0.2 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.23 CBY21600.1 - 0.01 15.6 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Pkinase_Tyr PF07714.17 CBY21601.1 - 4.4e-40 137.6 0.0 6.2e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY21601.1 - 5.9e-25 88.1 0.0 9e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CBY21603.1 - 1.1e-33 116.7 0.0 1.8e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21603.1 - 1.2e-27 96.9 0.0 2.8e-27 95.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY21603.1 - 0.001 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase She2p PF11435.8 CBY21604.1 - 0.02 14.6 0.2 0.043 13.5 0.0 1.6 2 0 0 2 2 2 0 RNA binding protein She2p OTOS PF15182.6 CBY21604.1 - 0.057 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Otospiralin Ras PF00071.22 CBY21605.1 - 2.6e-52 176.7 0.0 3.3e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY21605.1 - 9.5e-20 71.0 0.0 1.5e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY21605.1 - 3.2e-09 36.5 0.0 4.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY21605.1 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CBY21605.1 - 0.022 14.6 0.0 0.039 13.7 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 CBY21605.1 - 0.045 13.1 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBY21605.1 - 0.046 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Thioredoxin PF00085.20 CBY21606.1 - 4e-58 193.8 0.2 1.9e-31 108.1 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CBY21606.1 - 4.1e-34 118.1 0.0 5.7e-27 94.8 0.2 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY21606.1 - 2.6e-08 34.3 0.9 1.2e-06 28.9 0.0 3.3 4 1 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY21606.1 - 2.2e-07 31.0 0.0 0.0049 17.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CBY21606.1 - 5.3e-06 26.7 0.0 0.096 13.0 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 CBY21606.1 - 0.00016 21.1 0.0 0.0086 15.5 0.0 2.3 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 CBY21606.1 - 0.0021 17.1 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Calsequestrin ERp29_N PF07912.13 CBY21606.1 - 0.0028 17.8 0.0 0.15 12.2 0.0 3.2 3 1 0 3 3 3 1 ERp29, N-terminal domain AhpC-TSA PF00578.21 CBY21606.1 - 0.0029 17.5 0.2 2.4 8.1 0.0 2.9 2 1 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 CBY21606.1 - 0.0069 16.1 0.1 1.9 8.2 0.0 2.8 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 CBY21606.1 - 0.018 15.1 0.2 7 6.8 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin domain Guanylate_kin PF00625.21 CBY21607.1 - 1.8e-61 207.0 0.0 2.2e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 CBY21607.1 - 0.00018 22.0 0.4 0.0017 18.9 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY21607.1 - 0.00031 21.2 0.0 0.00059 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CBY21607.1 - 0.00031 21.1 0.0 0.002 18.5 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 CBY21607.1 - 0.00035 20.7 0.6 0.012 15.8 0.6 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBY21607.1 - 0.00073 19.5 0.0 0.0023 17.8 0.0 1.8 2 1 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 CBY21607.1 - 0.012 15.6 0.0 0.73 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CBY21607.1 - 0.014 15.1 0.1 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBY21607.1 - 0.028 15.0 0.0 0.047 14.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 CBY21607.1 - 0.029 14.4 0.1 0.058 13.5 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY21607.1 - 0.029 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CBY21607.1 - 0.032 14.6 0.4 0.096 13.1 0.1 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CBY21607.1 - 0.034 14.1 0.1 0.056 13.4 0.1 1.5 1 1 0 1 1 1 0 NTPase Rad17 PF03215.15 CBY21607.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain dNK PF01712.19 CBY21607.1 - 0.048 13.5 0.0 4.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_14 PF13173.6 CBY21607.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY21607.1 - 0.062 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 CBY21607.1 - 0.068 12.8 0.1 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 CBY21607.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CBY21607.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBY21607.1 - 0.084 13.3 0.7 0.86 10.0 0.7 2.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CBY21607.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CBY21607.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 CBY21607.1 - 0.15 12.2 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.13 CBY21609.1 - 2.1e-160 533.7 0.1 2.9e-160 533.2 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CBY21609.1 - 5e-26 90.6 0.1 1.7e-25 88.9 0.1 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CBY21609.1 - 5.6e-10 39.7 0.0 5.4e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBY21609.1 - 3.4e-08 33.4 0.1 8.1e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBY21609.1 - 8.7e-06 26.0 0.2 0.073 13.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_25 PF13481.6 CBY21609.1 - 3.9e-05 23.3 0.0 0.00091 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY21609.1 - 0.00011 22.6 0.0 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBY21609.1 - 0.00024 21.1 0.1 0.036 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBY21609.1 - 0.0042 16.5 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CBY21609.1 - 0.0055 16.4 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain DnaB_C PF03796.15 CBY21609.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_19 PF13245.6 CBY21609.1 - 0.018 15.4 2.1 0.26 11.6 1.4 2.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY21609.1 - 0.02 15.4 0.0 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBY21609.1 - 0.032 14.0 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CBY21609.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBY21609.1 - 0.056 12.9 0.1 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 CBY21609.1 - 0.07 12.6 0.0 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 CBY21609.1 - 0.096 12.7 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CBY21609.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TFIID-31kDa PF02291.15 CBY21609.1 - 0.14 12.3 0.2 0.98 9.5 0.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit zf-rbx1 PF12678.7 CBY21610.1 - 4e-13 49.4 8.1 1e-12 48.1 8.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBY21610.1 - 2e-10 40.9 5.4 3.6e-10 40.0 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CBY21610.1 - 5.4e-08 32.8 6.9 1.4e-07 31.5 6.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CBY21610.1 - 6.6e-08 32.3 4.5 1.2e-07 31.4 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY21610.1 - 5.6e-07 29.3 4.6 1.1e-06 28.4 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY21610.1 - 3.8e-05 23.5 3.3 6.3e-05 22.8 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY21610.1 - 0.00022 21.0 4.3 0.00049 19.9 4.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY21610.1 - 0.00031 20.4 0.7 0.00062 19.5 0.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBY21610.1 - 0.00075 19.5 0.8 0.0015 18.5 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY21610.1 - 0.0014 18.4 4.7 0.008 16.0 5.0 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBY21610.1 - 0.0067 16.0 3.7 0.012 15.2 3.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 CBY21610.1 - 0.023 14.6 4.1 0.049 13.5 4.1 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 CBY21610.1 - 0.032 14.2 3.0 0.12 12.3 3.0 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_9 PF13901.6 CBY21610.1 - 0.062 13.3 1.7 0.16 11.9 1.7 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_4 PF14570.6 CBY21610.1 - 0.1 12.4 3.7 0.2 11.5 3.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CBY21610.1 - 0.12 12.5 5.2 0.31 11.3 5.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 CBY21610.1 - 0.33 11.1 1.1 0.74 10.0 1.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 CBY21610.1 - 1.4 9.1 5.7 2.8 8.1 5.4 1.7 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 CBY21610.1 - 6.8 6.9 5.5 1.2 9.4 1.6 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Wtap PF17098.5 CBY21611.1 - 1.9e-50 170.8 15.5 1.9e-50 170.8 15.5 3.6 3 1 1 4 4 4 1 WTAP/Mum2p family BTB PF00651.31 CBY21611.1 - 9.5e-09 35.5 0.0 1.4e-07 31.7 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain HALZ PF02183.18 CBY21611.1 - 0.017 15.3 2.8 1.2 9.5 0.1 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper AAA_13 PF13166.6 CBY21611.1 - 0.52 8.9 17.7 0.86 8.2 17.7 1.2 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 CBY21611.1 - 1.4 9.1 33.4 1.4 9.1 18.9 2.9 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Peripla_BP_2 PF01497.18 CBY21611.1 - 6.4 6.3 7.6 0.6 9.6 1.0 2.7 4 0 0 4 4 4 0 Periplasmic binding protein Sod_Fe_C PF02777.18 CBY21613.1 - 1.6e-36 124.6 0.1 2.9e-36 123.7 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBY21613.1 - 2.3e-32 111.3 2.1 3.9e-32 110.5 2.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DNA_gyraseB PF00204.25 CBY21613.1 - 0.11 12.0 0.9 0.34 10.4 0.2 1.9 2 0 0 2 2 2 0 DNA gyrase B Wtap PF17098.5 CBY21614.1 - 2e-50 170.8 15.5 2e-50 170.8 15.5 3.6 3 1 1 4 4 4 1 WTAP/Mum2p family BTB PF00651.31 CBY21614.1 - 3.1e-13 49.9 0.0 6.3e-12 45.7 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain HALZ PF02183.18 CBY21614.1 - 0.0043 17.2 2.1 1.1 9.6 0.1 4.1 3 0 0 3 3 3 1 Homeobox associated leucine zipper AAA_13 PF13166.6 CBY21614.1 - 0.44 9.1 17.8 0.76 8.3 17.8 1.3 1 0 0 1 1 1 0 AAA domain Peripla_BP_2 PF01497.18 CBY21614.1 - 1.1 8.8 4.3 0.57 9.7 1.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein KLRAQ PF10205.9 CBY21614.1 - 7.7 6.8 21.5 0.083 13.1 6.6 3.7 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Sod_Fe_C PF02777.18 CBY21616.1 - 1.6e-36 124.6 0.1 2.9e-36 123.7 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBY21616.1 - 2.3e-32 111.3 2.1 3.9e-32 110.5 2.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DNA_gyraseB PF00204.25 CBY21616.1 - 0.11 12.0 0.9 0.34 10.4 0.2 1.9 2 0 0 2 2 2 0 DNA gyrase B ATE_C PF04377.15 CBY21617.1 - 2.1e-45 154.7 6.7 3.4e-45 154.0 6.7 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CBY21617.1 - 6.6e-25 87.3 2.3 6.6e-25 87.3 2.3 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus DUF5456 PF17539.2 CBY21617.1 - 0.22 11.4 1.5 0.54 10.1 1.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5456) IP_trans PF02121.18 CBY21618.1 - 7.2e-102 340.2 0.1 8.9e-102 339.9 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein CRS1_YhbY PF01985.21 CBY21618.1 - 0.061 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain ADH_zinc_N PF00107.26 CBY21619.1 - 2e-07 31.1 0.0 1.1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBY21619.1 - 0.00017 21.1 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_8 PF13450.6 CBY21619.1 - 0.029 14.6 0.1 0.081 13.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ADH_N PF08240.12 CBY21619.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain UDPG_MGDP_dh_N PF03721.14 CBY21619.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CBY21619.1 - 0.1 11.8 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 CBY21619.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SAS-6_N PF16531.5 CBY21620.1 - 5.8e-22 78.1 3.0 8.5e-20 71.1 0.3 2.9 3 1 0 3 3 3 2 Centriolar protein SAS N-terminal YvrJ PF12841.7 CBY21620.1 - 1.4 8.5 3.3 12 5.6 0.1 3.5 2 0 0 2 2 2 0 YvrJ protein family Choline_kinase PF01633.20 CBY21621.1 - 4.8e-09 36.1 1.1 2.8e-08 33.6 0.7 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kinase PF01633.20 CBY21622.1 - 0.00014 21.5 0.1 0.00042 20.0 0.0 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase CTP_transf_3 PF02348.19 CBY21622.1 - 0.0021 18.0 0.1 0.0024 17.8 0.1 1.2 1 1 0 1 1 1 1 Cytidylyltransferase DUF5617 PF18493.1 CBY21622.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) Choline_kinase PF01633.20 CBY21623.1 - 2.8e-24 85.9 0.0 4.2e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY21623.1 - 1.4e-07 31.7 0.0 1.9e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY21623.1 - 1.7e-05 24.3 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 CBY21624.1 - 7.1e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase CTP_transf_3 PF02348.19 CBY21624.1 - 0.022 14.7 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase Sld7_N PF18636.1 CBY21624.1 - 0.055 13.8 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain WD40 PF00400.32 CBY21625.1 - 8.3e-14 51.8 2.7 0.1 13.5 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21625.1 - 1.7e-08 34.7 0.6 0.77 10.1 0.0 5.7 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Pre-PUA PF17832.1 CBY21626.1 - 2.1e-25 89.2 1.3 2.9e-25 88.8 1.3 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CBY21626.1 - 1.5e-14 53.7 0.1 2.3e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 PUA domain Ras PF00071.22 CBY21627.1 - 3.3e-53 179.6 0.3 4.1e-53 179.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY21627.1 - 3.5e-29 101.5 0.0 6.3e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY21627.1 - 1.2e-09 37.9 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY21627.1 - 4.7e-05 23.4 0.4 0.12 12.3 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY21627.1 - 7.1e-05 22.4 0.1 0.00027 20.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY21627.1 - 0.00072 19.6 0.0 0.0011 19.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY21627.1 - 0.01 16.2 0.2 0.021 15.2 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF1327 PF07041.11 CBY21627.1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) ATPase PF06745.13 CBY21627.1 - 0.077 12.3 0.9 0.12 11.7 0.1 1.7 2 0 0 2 2 2 0 KaiC TniB PF05621.11 CBY21627.1 - 0.08 12.3 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein DUF2294 PF10057.9 CBY21627.1 - 0.086 13.0 1.0 0.69 10.1 1.0 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) FeoB_N PF02421.18 CBY21627.1 - 0.089 12.3 0.1 0.7 9.4 0.1 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF4490 PF14892.6 CBY21629.1 - 3.7e-05 23.7 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) CBM_2 PF00553.19 CBY21630.1 - 0.0047 17.2 3.9 0.019 15.3 1.3 2.6 2 0 0 2 2 2 1 Cellulose binding domain Ras PF00071.22 CBY21631.1 - 8.5e-60 201.0 0.2 9.9e-60 200.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY21631.1 - 3e-35 121.1 0.1 5.4e-35 120.2 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY21631.1 - 2.2e-12 46.8 0.1 2.7e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY21631.1 - 4.9e-05 23.4 0.0 0.0001 22.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBY21631.1 - 0.00024 20.5 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBY21631.1 - 0.00046 20.1 0.2 0.36 10.7 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY21631.1 - 0.00068 19.2 0.1 0.0015 18.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CBY21631.1 - 0.013 15.9 0.8 0.048 14.1 0.8 1.8 1 1 0 1 1 1 0 AAA ATPase domain Ribosomal_L30_N PF08079.12 CBY21631.1 - 0.22 11.8 2.4 5 7.4 0.0 2.3 1 1 1 2 2 2 0 Ribosomal L30 N-terminal domain zf-MYST PF17772.1 CBY21634.1 - 0.078 12.6 3.0 0.67 9.6 0.3 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2 PF00096.26 CBY21634.1 - 0.32 11.5 0.2 0.32 11.5 0.2 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type Sulfotransfer_3 PF13469.6 CBY21635.1 - 8.8e-08 32.8 0.2 9.8e-07 29.4 0.0 2.3 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY21635.1 - 3.3e-06 26.8 1.6 2.1e-05 24.1 1.6 2.2 1 1 0 1 1 1 1 Sulfotransferase domain SH3BP5 PF05276.14 CBY21636.1 - 6.2e-12 45.8 15.6 9.3e-12 45.2 15.6 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Peptidase_S48 PF03574.15 CBY21636.1 - 0.027 14.7 0.3 0.064 13.5 0.2 1.6 1 1 0 1 1 1 0 Peptidase family S48 SPATA24 PF15175.6 CBY21636.1 - 0.039 13.9 17.4 0.15 12.0 0.1 3.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 FAM194 PF14977.6 CBY21636.1 - 0.073 12.4 1.3 0.12 11.6 1.3 1.3 1 0 0 1 1 1 0 FAM194 protein DUF5601 PF18151.1 CBY21636.1 - 0.087 13.2 0.7 8.9 6.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) DUF910 PF06014.11 CBY21636.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF910) FapA PF03961.13 CBY21636.1 - 1.2 7.7 11.1 1.6 7.3 11.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 CBY21636.1 - 4.9 7.8 10.7 14 6.3 8.5 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CLCA PF08434.11 CBY21637.1 - 1.4e-21 77.1 3.9 8e-20 71.3 3.9 2.5 1 1 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 CBY21637.1 - 1.7e-10 41.4 0.0 6.2e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY21637.1 - 2.2e-07 31.5 0.0 6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY21637.1 - 0.00059 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 CBY21637.1 - 0.15 11.2 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Aldedh PF00171.22 CBY21638.1 - 3.9e-128 427.8 0.2 4.9e-128 427.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M19 PF01244.21 CBY21638.1 - 0.053 12.7 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) HLH PF00010.26 CBY21639.1 - 5.4e-11 42.3 0.9 5.4e-11 42.3 0.9 1.9 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 CBY21640.1 - 7.3e-11 41.9 0.7 7.3e-11 41.9 0.7 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Innexin PF00876.18 CBY21642.1 - 0.00077 18.8 0.8 0.0013 18.1 0.8 1.5 1 1 0 1 1 1 1 Innexin DUF3671 PF12420.8 CBY21642.1 - 0.37 10.9 0.0 0.37 10.9 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function DHHC PF01529.20 CBY21644.1 - 8.8e-35 119.7 15.4 8.8e-35 119.7 15.4 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase MqsA_antitoxin PF15731.5 CBY21644.1 - 0.14 12.3 1.0 0.39 10.8 0.7 1.8 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA FYVE PF01363.21 CBY21644.1 - 6.9 6.9 13.7 14 5.9 13.2 1.7 1 1 0 1 1 1 0 FYVE zinc finger PGK PF00162.19 CBY21645.1 - 6.8e-149 495.9 3.0 7.7e-149 495.7 3.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase MMgT PF10270.9 CBY21646.1 - 3.6e-10 40.1 0.0 4.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter zf-C2H2 PF00096.26 CBY21647.1 - 1.4e-06 28.4 15.6 0.0014 18.9 3.7 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY21647.1 - 4.1e-05 24.1 9.4 0.0051 17.5 1.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY21647.1 - 0.00044 20.5 9.9 0.068 13.5 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CBY21647.1 - 0.00073 20.2 4.8 0.0029 18.3 0.3 2.9 3 0 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CBY21647.1 - 0.0077 16.6 0.2 0.0077 16.6 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY21647.1 - 0.0078 16.5 2.7 0.12 12.7 0.1 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) RXT2_N PF08595.11 CBY21647.1 - 0.088 12.8 0.3 0.088 12.8 0.3 2.4 3 0 0 3 3 3 0 RXT2-like, N-terminal zf-C2H2_11 PF16622.5 CBY21647.1 - 0.14 11.9 3.8 0.45 10.3 0.4 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type TFIIS_C PF01096.18 CBY21647.1 - 9.6 6.2 6.9 1.1 9.1 0.5 2.7 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) 4HBT PF03061.22 CBY21648.1 - 2.7e-09 37.3 0.0 0.0031 17.8 0.0 2.8 2 1 0 2 2 2 2 Thioesterase superfamily DUF5532 PF17673.1 CBY21648.1 - 0.075 13.1 0.6 8.6 6.5 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5532) Zip PF02535.22 CBY21649.1 - 3.9e-27 95.3 16.7 5.4e-23 81.7 4.6 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter LETM1 PF07766.13 CBY21650.1 - 3.2e-81 272.6 0.8 6e-81 271.7 0.8 1.4 1 0 0 1 1 1 1 LETM1-like protein EF-hand_1 PF00036.32 CBY21650.1 - 0.00014 21.2 0.4 0.00036 19.9 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY21650.1 - 0.00034 21.0 0.1 0.021 15.3 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY21650.1 - 0.00066 19.1 0.8 0.0019 17.6 0.8 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBY21650.1 - 0.016 15.1 0.3 0.069 13.1 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 CBY21650.1 - 0.13 12.1 0.2 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF1053 PF06327.14 CBY21650.1 - 0.59 10.7 8.3 0.06 13.9 1.7 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) OmpH PF03938.14 CBY21650.1 - 2.1 8.7 12.1 0.88 9.9 3.7 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Tim17 PF02466.19 CBY21651.1 - 7.2e-18 65.0 5.8 9.7e-18 64.6 5.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CAF1 PF04857.20 CBY21652.1 - 1.4e-21 77.0 2.2 3.3e-10 39.6 0.5 2.3 2 1 0 2 2 2 2 CAF1 family ribonuclease RNase_H_2 PF13482.6 CBY21652.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 RNase_H superfamily Pfg27 PF09216.10 CBY21652.1 - 0.071 12.9 0.1 3.6 7.4 0.0 2.5 2 1 0 2 2 2 0 Pfg27 Ras PF00071.22 CBY21653.1 - 2.4e-60 202.8 1.7 3.1e-60 202.5 1.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY21653.1 - 3.3e-32 111.2 1.4 6.7e-32 110.2 1.4 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY21653.1 - 4.4e-15 55.6 0.3 5.9e-15 55.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY21653.1 - 2e-05 24.1 0.1 3.2e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBY21653.1 - 7.5e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY21653.1 - 9.8e-05 22.4 0.3 0.00018 21.6 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY21653.1 - 0.00063 19.3 0.3 0.0013 18.3 0.2 1.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBY21653.1 - 0.0019 17.8 0.0 0.79 9.2 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBY21653.1 - 0.0023 17.9 0.1 0.37 10.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CBY21653.1 - 0.014 15.7 0.0 0.027 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CBY21653.1 - 0.035 13.8 1.0 0.085 12.6 1.0 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 CBY21653.1 - 0.049 12.9 0.1 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Septin DBP10CT PF08147.12 CBY21653.1 - 0.056 13.7 1.2 0.07 13.4 0.1 1.7 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Tfb2_C PF18307.1 CBY21653.1 - 0.079 13.4 0.1 0.23 11.9 0.1 1.8 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain DUF2757 PF10955.8 CBY21653.1 - 0.12 12.7 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) FAD-SLDH PF12318.8 CBY21653.1 - 0.26 11.3 2.2 16 5.5 0.3 2.4 2 1 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF3890 PF13029.6 CBY21653.1 - 0.48 10.9 2.3 7.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3890) CAP PF00188.26 CBY21654.1 - 2.8e-07 31.4 0.2 9.2e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Sushi PF00084.20 CBY21654.1 - 0.0049 17.4 1.1 0.039 14.5 1.1 2.7 1 1 0 1 1 1 1 Sushi repeat (SCR repeat) UCH PF00443.29 CBY21655.1 - 1.9e-39 135.7 0.0 3.6e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY21655.1 - 4.1e-15 56.2 1.6 7.4e-09 35.6 0.1 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PHD PF00628.29 CBY21655.1 - 0.36 10.7 3.7 0.37 10.7 1.2 2.2 2 0 0 2 2 2 0 PHD-finger CarbpepA_inh PF02977.15 CBY21655.1 - 1.2 9.0 5.1 0.97 9.3 0.9 2.4 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Cofilin_ADF PF00241.20 CBY21656.1 - 5.2e-28 97.3 0.0 6.5e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoU_methylas_C PF12105.8 CBY21657.1 - 0.12 12.1 0.6 11 5.8 0.2 2.6 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal Mod_r PF07200.13 CBY21658.1 - 0.0053 16.9 0.2 0.0053 16.9 0.2 2.6 2 1 1 3 3 3 1 Modifier of rudimentary (Mod(r)) protein Laminin_I PF06008.14 CBY21658.1 - 0.07 12.8 10.9 0.14 11.8 3.8 2.2 1 1 1 2 2 2 0 Laminin Domain I COG5 PF10392.9 CBY21658.1 - 0.075 13.2 0.7 0.075 13.2 0.7 2.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Imm9 PF15587.6 CBY21658.1 - 0.076 12.7 1.0 5.4 6.7 0.4 2.6 2 1 0 2 2 2 0 Immunity protein 9 Baculo_PEP_C PF04513.12 CBY21658.1 - 0.12 12.4 0.3 0.68 10.0 0.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sulfatase_C PF14707.6 CBY21658.1 - 0.13 13.0 0.6 0.13 13.0 0.6 2.2 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase SecA_SW PF07516.13 CBY21658.1 - 0.45 10.5 10.2 1.1 9.3 10.2 1.7 1 1 0 1 1 1 0 SecA Wing and Scaffold domain T2SSF PF00482.23 CBY21658.1 - 0.82 9.6 2.3 3.2 7.7 0.4 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Fzo_mitofusin PF04799.13 CBY21658.1 - 2 7.9 4.4 1.8 8.1 0.7 2.1 2 0 0 2 2 2 0 fzo-like conserved region FAM76 PF16046.5 CBY21658.1 - 6.5 6.0 12.4 13 5.0 12.4 1.4 1 1 0 1 1 1 0 FAM76 protein DUF4404 PF14357.6 CBY21658.1 - 7.9 7.2 11.7 19 6.0 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Trypsin PF00089.26 CBY21659.1 - 1e-39 136.7 0.2 7.5e-27 94.6 0.0 2.9 2 1 0 2 2 2 2 Trypsin DUF1986 PF09342.11 CBY21659.1 - 0.0011 19.4 0.1 2.5 8.5 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin PF00089.26 CBY21660.1 - 9.3e-36 123.7 0.7 4.9e-29 101.7 0.1 2.1 2 0 0 2 2 2 2 Trypsin TypeIII_RM_meth PF12564.8 CBY21662.1 - 0.083 13.0 0.1 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit SNARE PF05739.19 CBY21662.1 - 0.25 11.4 1.4 0.46 10.5 0.1 2.0 2 0 0 2 2 2 0 SNARE domain Pup PF05639.11 CBY21662.1 - 0.37 11.7 8.0 5.7 7.9 0.0 2.6 1 1 1 2 2 2 0 Pup-like protein Connexin PF00029.19 CBY21663.1 - 2.2e-73 246.9 0.2 3.6e-42 144.8 0.3 2.1 2 0 0 2 2 2 2 Connexin Guanylate_cyc_2 PF09778.9 CBY21664.1 - 0.06 12.7 0.2 0.092 12.1 0.2 1.3 1 0 0 1 1 1 0 Guanylylate cyclase Nup35_RRM PF05172.13 CBY21665.1 - 8.1e-21 73.9 0.1 1.6e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CBY21665.1 - 5.5e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CBY21665.1 - 0.009 15.8 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC6 PF05460.13 CBY21665.1 - 3.6 6.8 10.2 4.1 6.6 2.2 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) TUDOR PF00567.24 CBY21666.1 - 8.7e-05 22.5 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 Tudor domain zf-CCCH_4 PF18044.1 CBY21666.1 - 0.035 13.9 0.5 0.084 12.7 0.5 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY21666.1 - 0.041 13.9 0.5 0.041 13.9 0.5 2.1 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 CBY21666.1 - 0.047 13.6 0.4 0.047 13.6 0.4 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2 PF00096.26 CBY21669.1 - 6.1e-21 73.6 45.3 6.5e-05 23.2 3.1 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY21669.1 - 1.9e-19 68.7 41.1 0.001 19.7 0.9 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY21669.1 - 1.8e-09 37.6 48.7 0.01 16.2 0.8 6.9 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY21669.1 - 2.4e-09 37.2 33.9 0.0045 17.2 0.2 6.7 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CBY21669.1 - 8.2e-09 35.6 26.6 2.8e-05 24.3 2.7 3.8 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY21669.1 - 9.2e-06 25.9 18.7 4.9 7.7 0.2 5.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY21669.1 - 0.00072 19.5 42.5 0.015 15.3 0.0 7.1 6 1 1 7 7 7 4 C2H2-type zinc finger GAGA PF09237.11 CBY21669.1 - 0.0082 15.9 10.5 0.27 11.1 0.8 3.9 3 1 1 4 4 4 1 GAGA factor zf-BED PF02892.15 CBY21669.1 - 0.042 13.9 35.5 0.48 10.5 2.6 5.5 3 1 3 6 6 6 0 BED zinc finger zf-H2C2_5 PF13909.6 CBY21669.1 - 0.051 13.3 46.3 0.27 11.0 1.0 7.1 6 1 0 6 6 6 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CBY21669.1 - 0.067 13.0 22.9 5.5 6.9 1.2 5.7 5 1 1 6 6 6 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 CBY21669.1 - 0.18 11.7 0.4 0.18 11.7 0.4 6.2 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-RING_7 PF02591.15 CBY21669.1 - 0.67 10.2 10.5 0.82 9.9 0.3 4.0 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf_UBZ PF18439.1 CBY21669.1 - 1.1 8.9 21.6 11 5.7 0.1 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 CBY21669.1 - 2.2 8.3 22.8 0.31 11.0 0.4 4.4 1 1 4 5 5 5 0 zinc-ribbons DUF2256 PF10013.9 CBY21669.1 - 2.6 8.3 17.1 11 6.2 0.1 5.2 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.10 CBY21669.1 - 6.2 7.0 28.0 2 8.6 0.8 4.8 2 2 3 5 5 5 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 CBY21669.1 - 7.7 6.5 13.5 8 6.4 0.1 4.3 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 CBY21669.1 - 9.8 6.7 32.0 0.82 10.2 3.5 5.5 2 2 4 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger DUF572 PF04502.13 CBY21670.1 - 7e-74 249.4 27.5 8.6e-73 245.8 27.0 2.0 1 1 1 2 2 2 1 Family of unknown function (DUF572) Porphobil_deam PF01379.20 CBY21670.1 - 0.0035 16.9 1.0 0.0061 16.1 1.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain zf-PHD-like PF15446.6 CBY21670.1 - 0.22 11.1 1.6 2 8.0 1.7 2.5 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Lipoprotein_10 PF03202.13 CBY21670.1 - 1 9.8 8.6 0.051 14.0 1.9 2.2 2 1 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region SRR1 PF07985.12 CBY21671.1 - 3.4e-06 27.0 0.0 6.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 SRR1 Kelch_1 PF01344.25 CBY21672.1 - 9.6e-75 246.0 21.5 3.6e-15 55.3 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CBY21672.1 - 9.7e-37 124.1 5.2 2.5e-06 27.6 0.1 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 CBY21672.1 - 7e-35 119.2 1.1 9.7e-35 118.8 0.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CBY21672.1 - 2e-27 95.6 3.8 3.7e-27 94.8 3.8 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CBY21672.1 - 1.2e-16 60.4 9.2 0.00092 19.2 0.1 6.2 4 1 2 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY21672.1 - 2e-15 56.6 7.4 0.0065 16.7 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY21672.1 - 2.3e-11 43.2 12.0 0.056 13.4 0.2 6.3 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.8 CBY21672.1 - 8.3e-06 25.9 2.9 0.00039 20.5 1.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_5 PF13854.6 CBY21672.1 - 2.9e-05 23.9 7.0 0.69 10.0 0.1 5.2 5 0 0 5 5 5 1 Kelch motif Glu_cyclase_2 PF05096.12 CBY21672.1 - 0.068 12.6 0.0 0.93 8.9 0.0 2.5 2 1 1 3 3 3 0 Glutamine cyclotransferase Skp1_POZ PF03931.15 CBY21672.1 - 0.086 13.0 0.2 0.3 11.3 0.1 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain ubiquitin PF00240.23 CBY21673.1 - 1.9e-34 117.2 0.4 2.6e-34 116.8 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CBY21673.1 - 1.5e-30 104.9 14.2 2.2e-30 104.3 14.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CBY21673.1 - 1.8e-16 59.7 0.5 2.6e-16 59.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBY21673.1 - 1.6e-05 25.3 0.1 6.5e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CBY21673.1 - 0.0027 18.0 0.1 0.0053 17.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBY21673.1 - 0.0046 16.9 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBY21673.1 - 0.0047 17.0 0.1 0.01 15.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBY21673.1 - 0.014 15.4 1.2 4.2 7.5 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CBY21673.1 - 0.018 15.6 0.1 0.021 15.4 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_L14 PF00238.19 CBY21674.1 - 7e-34 116.5 0.1 7.8e-34 116.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TPT PF03151.16 CBY21675.1 - 8.9e-19 67.9 15.9 1.1e-18 67.6 15.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CBY21675.1 - 4.3e-08 32.7 20.6 6.3e-08 32.2 20.6 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBY21675.1 - 0.0016 18.6 30.0 0.046 13.9 15.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Pkinase_Tyr PF07714.17 CBY21676.1 - 1.4e-25 90.0 0.0 4e-25 88.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY21676.1 - 6.5e-25 88.0 0.0 1.2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY21676.1 - 0.0008 18.3 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EIF_2_alpha PF07541.12 CBY21677.1 - 1e-33 115.8 1.8 2.4e-33 114.7 0.4 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CBY21677.1 - 4.1e-13 49.5 0.2 7.5e-13 48.6 0.2 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Mst1_SARAH PF11629.8 CBY21677.1 - 0.0088 16.1 0.0 0.037 14.1 0.0 2.1 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 AcetDehyd-dimer PF09290.11 CBY21677.1 - 0.012 15.8 0.2 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation DUF4407 PF14362.6 CBY21677.1 - 0.047 13.1 0.3 0.072 12.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Metallophos PF00149.28 CBY21678.1 - 2.1e-35 123.1 0.9 3.3e-35 122.4 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBY21678.1 - 0.019 15.4 0.1 0.046 14.2 0.1 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-TAZ PF02135.16 CBY21678.1 - 0.021 15.3 0.2 0.054 14.0 0.2 1.7 1 0 0 1 1 1 0 TAZ zinc finger Glyco_hydro_65N PF03636.15 CBY21678.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain MRP-S22 PF10245.9 CBY21679.1 - 2e-28 99.8 0.1 4e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 Trypsin PF00089.26 CBY21680.1 - 8.8e-09 35.5 0.7 1e-08 35.3 0.7 1.0 1 0 0 1 1 1 1 Trypsin ATP_synt_H PF05493.13 CBY21681.1 - 4.5e-20 71.9 9.0 5.5e-20 71.6 9.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit H HEAT PF02985.22 CBY21682.1 - 1.9e-07 30.7 2.9 20 5.8 0.0 7.6 7 0 0 7 7 7 1 HEAT repeat Vac14_Fab1_bd PF12755.7 CBY21682.1 - 0.00017 22.1 2.3 3.9 8.1 0.0 5.7 6 2 1 7 7 7 1 Vacuolar 14 Fab1-binding region Herpes_heli_pri PF05774.11 CBY21682.1 - 0.012 15.9 0.3 0.038 14.2 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus helicase-primase complex component Cohesin_HEAT PF12765.7 CBY21682.1 - 0.018 15.4 2.2 22 5.5 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 CBY21682.1 - 0.023 14.7 7.0 23 5.0 0.2 5.1 5 2 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CBY21682.1 - 0.025 15.1 0.0 33 5.1 0.0 4.7 6 0 0 6 6 6 0 HEAT-like repeat Nmad5 PF18757.1 CBY21684.1 - 0.00092 19.5 3.1 0.0013 19.0 3.1 1.3 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 PCRF PF03462.18 CBY21684.1 - 5.8 6.7 10.0 4.7 7.0 6.2 2.1 2 0 0 2 2 2 0 PCRF domain PHD PF00628.29 CBY21685.1 - 0.0015 18.4 14.7 0.0015 18.4 14.7 4.0 3 1 2 5 5 5 1 PHD-finger Spore_Cse60 PF10957.8 CBY21685.1 - 0.047 13.7 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Sporulation protein Cse60 RNase_PH_C PF03725.15 CBY21685.1 - 0.064 13.3 0.7 0.29 11.2 0.2 2.3 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Ppx-GppA PF02541.16 CBY21685.1 - 0.12 11.8 0.6 0.16 11.4 0.6 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family ZU5 PF00791.20 CBY21686.1 - 1.4e-21 76.7 0.2 3.4e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 ZU5 domain Nmad5 PF18757.1 CBY21688.1 - 0.00036 20.8 2.3 0.00043 20.6 2.3 1.1 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 DUF3740 PF12548.8 CBY21688.1 - 0.019 15.4 2.8 0.029 14.8 2.8 1.4 1 0 0 1 1 1 0 Sulfatase protein BLOC1_2 PF10046.9 CBY21688.1 - 0.29 11.5 6.5 2.6 8.4 0.6 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-UBR PF02207.20 CBY21689.1 - 3.6e-10 39.9 15.5 3.6e-10 39.9 15.5 3.5 1 1 3 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 CBY21689.1 - 0.0017 18.2 15.1 0.0017 18.2 15.1 4.0 3 1 2 5 5 5 1 PHD-finger ZU5 PF00791.20 CBY21690.1 - 2.5e-19 69.4 0.1 3e-16 59.6 0.0 2.3 2 0 0 2 2 2 2 ZU5 domain PIG-U PF06728.13 CBY21691.1 - 1.5e-18 67.0 17.4 1e-17 64.3 17.4 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U PIG-U PF06728.13 CBY21692.1 - 4.6e-07 29.2 1.4 7.1e-07 28.6 1.4 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Transgly_assoc PF04226.13 CBY21692.1 - 0.035 14.4 0.8 0.051 13.8 0.8 1.2 1 0 0 1 1 1 0 Transglycosylase associated protein Acetyltransf_1 PF00583.25 CBY21693.1 - 2.2e-21 76.3 0.1 2.8e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY21693.1 - 3.7e-13 49.7 0.0 5.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY21693.1 - 1e-12 48.1 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY21693.1 - 9e-09 35.2 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CBY21693.1 - 1.9e-07 31.8 0.0 2.2e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY21693.1 - 1.8e-06 28.0 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CBY21693.1 - 4.5e-06 26.4 0.0 6.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY21693.1 - 0.0054 16.8 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 CBY21693.1 - 0.04 14.1 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PBC PF03792.13 CBY21694.1 - 5e-76 254.7 3.6 6e-76 254.4 3.6 1.0 1 0 0 1 1 1 1 PBC domain RPN7 PF10602.9 CBY21694.1 - 0.022 14.5 0.2 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Peptidase_C97 PF05903.14 CBY21694.1 - 0.13 12.1 0.3 0.42 10.4 0.3 1.8 1 1 0 1 1 1 0 PPPDE putative peptidase domain Tropomodulin PF03250.14 CBY21695.1 - 7.4e-48 162.2 4.4 1.9e-47 160.9 4.4 1.6 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.6 CBY21695.1 - 0.0034 17.3 2.8 0.032 14.3 0.1 2.9 2 0 0 2 2 2 1 Leucine Rich repeat LRR_4 PF12799.7 CBY21695.1 - 2.8 8.5 8.2 1.2 9.6 0.5 3.1 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) NACHT PF05729.12 CBY21696.1 - 0.14 12.0 0.1 0.62 10.0 0.1 1.9 2 0 0 2 2 2 0 NACHT domain DUF3926 PF13080.6 CBY21697.1 - 1.5 8.8 6.2 8.5 6.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) ThiF PF00899.21 CBY21699.1 - 1e-29 103.7 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family WD40 PF00400.32 CBY21700.1 - 4.7e-11 43.1 3.6 0.008 17.0 0.2 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21700.1 - 0.01 16.1 0.0 0.23 11.8 0.0 3.0 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY21700.1 - 0.058 12.3 0.0 7.7 5.4 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DEAD PF00270.29 CBY21701.1 - 4.5e-32 111.2 0.0 1e-31 110.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY21701.1 - 2.5e-20 72.9 0.0 9.2e-20 71.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY21701.1 - 0.0003 20.8 0.0 0.00063 19.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNase_PH PF01138.21 CBY21703.1 - 1.5e-33 116.1 0.3 2.6e-33 115.3 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RhoGAP PF00620.27 CBY21704.1 - 4.6e-27 94.7 0.0 1.1e-26 93.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 CBY21704.1 - 2.1e-16 60.4 0.0 2.2e-15 57.1 0.0 2.5 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 CBY21704.1 - 9e-07 28.9 1.4 7.2e-05 22.8 1.6 2.7 2 0 0 2 2 2 1 WW domain DUF4551 PF15087.6 CBY21704.1 - 1.6 7.4 9.5 2.5 6.8 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3439 PF11921.8 CBY21705.1 - 0.0019 18.2 1.7 0.0022 18.0 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) DHHC PF01529.20 CBY21706.1 - 0.15 12.2 1.6 0.82 9.8 0.5 2.1 2 1 0 2 2 2 0 DHHC palmitoyltransferase Jagunal PF07086.12 CBY21706.1 - 0.15 12.1 0.2 0.15 12.1 0.2 1.5 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis Ion_trans PF00520.31 CBY21707.1 - 3.3e-31 108.4 9.4 4.8e-31 107.9 9.4 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY21707.1 - 4.5e-11 42.7 0.0 8.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CBY21707.1 - 1e-10 41.4 0.2 1e-10 41.4 0.2 2.9 4 0 0 4 4 4 1 Ion channel Kinesin PF00225.23 CBY21708.1 - 7.9e-97 324.2 4.0 7.9e-97 324.2 4.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY21708.1 - 1.7e-19 70.2 1.5 2.3e-18 66.6 0.2 3.4 2 1 0 2 2 2 1 Microtubule binding FHA PF00498.26 CBY21708.1 - 1.1e-05 25.7 0.8 0.00032 21.0 0.3 2.8 2 0 0 2 2 2 1 FHA domain ApoO PF09769.9 CBY21708.1 - 0.48 10.4 3.7 9.4 6.2 1.6 2.9 2 0 0 2 2 2 0 Apolipoprotein O Y_phosphatase PF00102.27 CBY21709.1 - 1e-42 146.4 0.0 1.4e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pkinase PF00069.25 CBY21710.1 - 2.1e-72 243.6 0.0 3.5e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21710.1 - 4.4e-42 144.2 0.0 1.1e-41 142.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.19 CBY21710.1 - 2.4e-09 36.9 0.0 5.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 CBY21710.1 - 2.7e-08 33.4 0.1 4.9e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY21710.1 - 2.7e-07 30.2 0.0 1.2e-06 28.0 0.0 2.0 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 CBY21710.1 - 9.7e-06 24.8 0.6 1.5e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBY21710.1 - 8.6e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY21710.1 - 0.0005 19.7 0.1 0.0015 18.2 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase G8 PF10162.9 CBY21711.1 - 1.4e-38 131.7 1.0 4e-29 101.2 0.2 2.8 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 CBY21711.1 - 3.2e-17 62.4 21.7 0.00016 21.7 0.4 8.5 8 1 0 8 8 8 5 IPT/TIG domain Beta_helix PF13229.6 CBY21711.1 - 1.3e-08 34.9 37.8 6.1e-05 22.9 2.0 6.2 7 0 0 7 7 7 3 Right handed beta helix region LRR_9 PF14580.6 CBY21711.1 - 0.00065 19.2 3.3 0.0016 18.0 3.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBY21711.1 - 0.0018 18.0 0.8 0.0018 18.0 0.8 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CBY21711.1 - 0.11 13.0 11.1 0.055 13.9 2.2 3.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Ribo_biogen_C PF04034.13 CBY21712.1 - 3.2e-49 165.9 0.0 4.1e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CBY21712.1 - 6.2e-12 45.1 1.0 1.1e-11 44.3 1.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Myb_DNA-bind_4 PF13837.6 CBY21713.1 - 3.1e-09 37.1 7.6 6e-05 23.4 1.2 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CBY21713.1 - 0.001 20.0 4.6 0.049 14.6 0.3 2.8 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CBY21713.1 - 0.0049 17.2 3.4 0.007 16.7 0.4 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF573 PF04504.14 CBY21713.1 - 0.028 15.1 0.9 0.71 10.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF573 WD40_alt PF14077.6 CBY21714.1 - 0.1 12.4 0.3 0.26 11.2 0.3 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif PIP5K PF01504.18 CBY21715.1 - 4.2e-84 282.0 0.2 6e-84 281.5 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Arcadin_1 PF18653.1 CBY21716.1 - 0.01 15.9 0.6 6.8 6.8 0.0 2.8 3 0 0 3 3 3 0 Arcadin 1 Peptidase_M2 PF01401.18 CBY21717.1 - 3.8e-85 286.7 0.5 5.3e-85 286.2 0.5 1.2 1 0 0 1 1 1 1 Angiotensin-converting enzyme Zip PF02535.22 CBY21718.1 - 1.9e-14 53.6 0.2 2.5e-14 53.2 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 CBY21719.1 - 1.1e-14 54.4 0.6 1.2e-14 54.3 0.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter GreA_GreB_N PF03449.15 CBY21720.1 - 0.0094 16.1 2.3 0.03 14.5 2.3 2.0 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal KxDL PF10241.9 CBY21720.1 - 0.014 15.7 3.2 0.014 15.7 3.2 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein CREPT PF16566.5 CBY21720.1 - 0.07 13.3 6.1 0.12 12.6 5.4 1.8 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Cep57_CLD PF14073.6 CBY21720.1 - 0.072 13.1 11.4 0.15 12.1 11.4 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Occludin_ELL PF07303.13 CBY21720.1 - 5.1 7.9 19.9 0.18 12.5 2.8 3.9 2 1 2 4 4 4 0 Occludin homology domain Pkinase PF00069.25 CBY21721.1 - 2.7e-47 161.4 0.0 3.3e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21721.1 - 3.9e-16 59.1 0.0 6.1e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY21721.1 - 7.1e-09 35.4 0.0 1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY21721.1 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY21721.1 - 2e-05 23.6 0.0 3.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY21721.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBY21721.1 - 0.028 14.0 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CBY21721.1 - 0.042 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Piwi PF02171.17 CBY21722.1 - 1.2e-103 346.6 0.9 1.6e-103 346.1 0.9 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CBY21722.1 - 1e-20 74.7 0.0 2.4e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 CBY21722.1 - 5.9e-18 65.0 0.0 1.5e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CBY21722.1 - 5.6e-15 54.8 0.0 1.6e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CBY21722.1 - 9e-12 45.1 0.0 2.7e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 CBY21722.1 - 7.4e-05 22.9 0.1 0.0008 19.6 0.0 2.9 2 0 0 2 2 2 1 Mid domain of argonaute ubiquitin PF00240.23 CBY21723.1 - 3.6e-05 23.4 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family HrpB7 PF09486.10 CBY21723.1 - 0.042 14.2 2.3 0.049 14.0 1.6 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FeoA PF04023.14 CBY21723.1 - 0.059 13.6 0.2 12 6.3 0.0 2.6 2 0 0 2 2 2 0 FeoA domain DUF1003 PF06210.11 CBY21724.1 - 0.1 12.7 0.1 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) PhoPQ_related PF10142.9 CBY21725.1 - 2.9e-89 299.3 0.5 3.7e-89 299.0 0.5 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Med18 PF09637.10 CBY21726.1 - 2.4e-25 89.8 0.0 3.3e-18 66.4 0.0 2.1 1 1 1 2 2 2 2 Med18 protein PDZ PF00595.24 CBY21727.1 - 5.2e-167 542.7 66.9 1.1e-15 57.7 0.1 14.3 13 1 1 14 14 14 14 PDZ domain PDZ_6 PF17820.1 CBY21727.1 - 1.7e-103 338.4 40.3 2.3e-10 40.1 0.1 14.5 14 0 0 14 14 14 14 PDZ domain PDZ_2 PF13180.6 CBY21727.1 - 1.3e-78 259.3 37.8 3.4e-08 33.7 0.1 14.5 14 0 0 14 14 14 14 PDZ domain Tricorn_PDZ PF14685.6 CBY21727.1 - 1.2e-09 38.0 15.5 0.8 9.7 0.1 10.9 12 0 0 12 12 12 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 CBY21727.1 - 0.01 16.2 0.7 13 6.2 0.0 5.6 7 0 0 7 7 7 0 PDZ domain Cwf_Cwc_15 PF04889.12 CBY21727.1 - 1.1 9.0 7.0 5 6.8 0.3 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4061 PF13270.6 CBY21728.1 - 0.1 12.9 0.2 0.1 12.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) 5-FTHF_cyc-lig PF01812.20 CBY21729.1 - 1.4e-21 77.2 0.0 2.1e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family KH_9 PF17904.1 CBY21731.1 - 1.5e-16 60.5 0.2 7.2e-16 58.3 0.2 2.1 2 0 0 2 2 2 1 FMRP KH0 domain KH_1 PF00013.29 CBY21731.1 - 6.8e-12 45.0 0.6 8.5e-07 28.7 0.1 2.8 2 0 0 2 2 2 2 KH domain Agenet PF05641.12 CBY21731.1 - 0.00025 21.5 0.4 0.0014 19.1 0.0 2.4 3 0 0 3 3 3 1 Agenet domain dUTPase PF00692.19 CBY21731.1 - 0.055 13.1 0.1 0.32 10.7 0.0 2.2 2 1 1 3 3 3 0 dUTPase KH_2 PF07650.17 CBY21731.1 - 0.4 10.5 2.6 11 6.0 0.1 2.8 2 1 1 3 3 3 0 KH domain Pex14_N PF04695.13 CBY21731.1 - 1.8 9.2 9.7 3.2 8.4 9.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Androgen_recep PF02166.16 CBY21731.1 - 8.8 5.0 12.6 15 4.3 12.6 1.3 1 0 0 1 1 1 0 Androgen receptor DUF5349 PF17298.2 CBY21731.1 - 8.9 6.0 21.0 16 5.1 21.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Trehalose_PPase PF02358.16 CBY21732.1 - 0.05 12.7 0.3 0.051 12.7 0.3 1.1 1 0 0 1 1 1 0 Trehalose-phosphatase HTH_32 PF13565.6 CBY21733.1 - 0.0011 19.6 4.1 0.089 13.4 0.0 3.9 3 1 0 3 3 3 1 Homeodomain-like domain SCAPER_N PF16501.5 CBY21733.1 - 0.0012 18.8 0.3 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 S phase cyclin A-associated protein in the endoplasmic reticulum HTH_38 PF13936.6 CBY21733.1 - 0.015 15.0 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain LcrG PF07216.12 CBY21733.1 - 0.028 14.4 2.3 0.69 9.9 0.2 2.6 2 0 0 2 2 2 0 LcrG protein DUF2999 PF11212.8 CBY21733.1 - 0.073 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) RasGEF_N PF00618.20 CBY21733.1 - 0.78 10.0 4.4 7.5 6.8 0.2 3.1 3 0 0 3 3 3 0 RasGEF N-terminal motif Amnionless PF14828.6 CBY21734.1 - 1.3e-06 27.6 0.3 6.3e-05 22.0 0.0 2.0 2 0 0 2 2 2 2 Amnionless FtsX_ECD PF18075.1 CBY21734.1 - 0.86 10.3 4.9 4.7 7.9 0.5 2.6 3 0 0 3 3 3 0 FtsX extracellular domain Aminotran_1_2 PF00155.21 CBY21735.1 - 9.3e-69 232.3 0.0 1.1e-68 232.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CBY21735.1 - 3e-06 26.8 0.0 4.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CBY21735.1 - 0.00036 19.6 0.0 0.0005 19.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 CBY21735.1 - 0.00043 19.0 0.0 0.00084 18.1 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.20 CBY21735.1 - 0.0045 15.6 0.0 0.0066 15.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CBY21735.1 - 0.0059 15.9 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 CBY21735.1 - 0.028 13.2 0.0 0.068 11.9 0.0 1.6 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase SepSecS PF05889.13 CBY21735.1 - 0.086 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Glyco_transf_7N PF13733.6 CBY21737.1 - 2.5e-23 82.2 0.7 4.6e-23 81.3 0.7 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY21737.1 - 5.5e-23 80.4 0.8 1.3e-22 79.3 0.8 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase VWA PF00092.28 CBY21738.1 - 1.8e-30 106.4 1.3 2.9e-30 105.8 1.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_transf_7C PF02709.14 CBY21738.1 - 5.2e-21 74.1 1.0 1e-20 73.2 1.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase VWA_2 PF13519.6 CBY21738.1 - 3.4e-12 47.0 0.1 6e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_transf_7N PF13733.6 CBY21738.1 - 8e-11 41.7 0.9 1.5e-10 40.8 0.9 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 VWA_3 PF13768.6 CBY21738.1 - 1.1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CUB PF00431.20 CBY21738.1 - 0.00044 20.6 0.7 0.0048 17.2 0.1 2.9 3 1 0 3 3 3 1 CUB domain CobT_C PF11775.8 CBY21738.1 - 0.15 11.6 0.0 0.41 10.2 0.0 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain EB PF01683.18 CBY21738.1 - 2.4 8.5 19.8 1.2 9.5 4.0 3.4 2 1 1 3 3 3 0 EB module VWA PF00092.28 CBY21739.1 - 1.3e-30 106.9 1.3 2.5e-30 106.0 1.3 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY21739.1 - 2.7e-12 47.3 0.1 5.2e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY21739.1 - 9.2e-06 25.7 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CUB PF00431.20 CBY21739.1 - 0.0011 19.3 0.3 0.01 16.1 0.1 2.6 2 1 0 2 2 2 1 CUB domain CobT_C PF11775.8 CBY21739.1 - 0.13 11.9 0.0 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain EB PF01683.18 CBY21739.1 - 1.7 9.0 19.9 1 9.7 4.0 3.5 2 1 1 3 3 3 0 EB module SH3_9 PF14604.6 CBY21740.1 - 1e-38 130.9 0.8 7.9e-14 51.3 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 CBY21740.1 - 1.5e-38 130.1 3.5 4e-14 52.0 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBY21740.1 - 8.8e-27 92.6 0.1 8.8e-08 31.7 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain EF-hand_4 PF12763.7 CBY21740.1 - 1e-20 73.6 0.0 1.2e-10 41.3 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CBY21740.1 - 5.9e-11 41.1 0.3 3e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY21740.1 - 5.2e-08 32.2 0.1 0.003 17.4 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY21740.1 - 1.3e-07 31.9 0.0 0.00017 21.9 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY21740.1 - 9.8e-07 28.5 0.1 0.025 14.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY21740.1 - 3.4e-05 23.1 0.1 0.0012 18.3 0.0 2.5 2 0 0 2 2 2 1 EF hand SH3_3 PF08239.11 CBY21740.1 - 0.0026 18.0 0.3 0.43 10.9 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_16 PF18348.1 CBY21740.1 - 0.0096 15.7 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 Bacterial dipeptidyl-peptidase Sh3 domain Y_phosphatase PF00102.27 CBY21741.1 - 2.1e-39 135.5 0.0 3.2e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY21741.1 - 0.00066 19.7 0.0 0.0013 18.7 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 CBY21741.1 - 0.011 15.6 0.2 0.025 14.4 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Raco_middle PF17651.1 CBY21741.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 RACo middle region 2OG-FeII_Oxy_3 PF13640.6 CBY21742.1 - 6.3e-09 36.6 0.0 8.9e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phospholip_A2_1 PF00068.19 CBY21744.1 - 2.6e-18 66.5 9.0 2.6e-18 66.5 9.0 1.8 2 0 0 2 2 2 1 Phospholipase A2 Pkinase_Tyr PF07714.17 CBY21745.1 - 1.9e-31 109.3 0.0 2.8e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY21745.1 - 1.7e-10 40.7 0.0 3.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PARP_regulatory PF01358.18 CBY21745.1 - 0.023 13.7 0.4 0.042 12.8 0.4 1.3 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit GAGBD PF16828.5 CBY21745.1 - 0.023 14.8 0.4 0.25 11.4 0.1 2.6 3 0 0 3 3 3 0 GAG-binding domain on surface antigen Gar1 PF04410.14 CBY21748.1 - 7.6e-36 123.2 0.0 1e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region UBX PF00789.20 CBY21749.1 - 0.091 13.0 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 UBX domain p450 PF00067.22 CBY21750.1 - 4.4e-71 240.0 0.0 6.6e-71 239.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 CBY21751.1 - 6.6e-24 84.3 0.4 6.2e-23 81.1 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 CBY21751.1 - 3.3e-19 68.9 0.9 3.5e-18 65.6 0.5 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 CBY21751.1 - 1.1e-11 44.9 0.1 7.5e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 F5/8 type C domain DUF2935 PF11155.8 CBY21751.1 - 0.017 15.4 0.0 0.8 10.0 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 CBY21752.1 - 0.0011 19.0 0.3 0.13 12.3 0.1 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CBY21752.1 - 0.0014 18.7 6.1 0.013 15.5 2.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Prominin PF05478.11 CBY21752.1 - 0.002 16.2 2.3 0.002 16.2 2.3 1.5 1 1 1 2 2 2 1 Prominin KIX PF02172.16 CBY21752.1 - 0.027 14.7 1.4 0.082 13.2 1.4 1.8 1 0 0 1 1 1 0 KIX domain DUF1515 PF07439.11 CBY21752.1 - 0.058 13.4 2.9 0.3 11.1 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) DUF2115 PF09888.9 CBY21752.1 - 0.16 12.5 5.2 0.29 11.6 4.3 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Fzo_mitofusin PF04799.13 CBY21752.1 - 0.67 9.5 7.5 0.16 11.5 3.3 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF883 PF05957.13 CBY21752.1 - 2.3 8.9 7.2 2.8 8.6 0.1 2.9 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 CBY21752.1 - 4.1 6.7 6.4 5.8 6.2 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.26 CBY21753.1 - 5.9e-23 80.0 35.0 1.9e-06 28.0 3.8 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY21753.1 - 1e-20 73.1 30.8 4.4e-09 36.4 1.7 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY21753.1 - 1.2e-14 53.7 33.4 0.0004 21.0 2.7 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY21753.1 - 1.4e-06 27.9 15.6 0.075 12.8 0.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CBY21753.1 - 3.2e-05 24.1 20.0 0.047 14.0 0.9 4.8 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CBY21753.1 - 6.8e-05 23.1 16.6 0.0023 18.2 5.3 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 CBY21753.1 - 0.0024 17.6 2.2 0.0024 17.6 2.2 5.2 5 0 0 5 5 5 2 zinc-finger C2H2-type DUF4764 PF15961.5 CBY21753.1 - 0.0063 15.3 9.1 0.076 11.7 2.4 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4764) zf-met PF12874.7 CBY21753.1 - 0.026 14.9 20.3 0.082 13.3 1.6 4.7 4 1 0 4 4 4 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CBY21753.1 - 0.2 11.8 15.6 3.6 7.8 4.2 3.8 3 1 0 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 CBY21753.1 - 9.7 5.9 12.4 6.5 6.4 0.2 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 CBY21754.1 - 1.4e-09 37.8 20.2 0.001 19.4 2.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY21754.1 - 3.5e-09 36.7 19.1 0.014 16.2 2.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY21754.1 - 0.012 15.6 18.9 0.39 10.8 0.9 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Pellino PF04710.14 CBY21754.1 - 0.025 13.2 2.9 0.033 12.9 2.9 1.2 1 0 0 1 1 1 0 Pellino zf-Di19 PF05605.12 CBY21754.1 - 0.067 13.5 8.7 0.12 12.7 1.1 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_SprT PF17283.2 CBY21754.1 - 0.068 13.1 0.8 0.068 13.1 0.8 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_2 PF12756.7 CBY21754.1 - 0.082 13.3 10.7 1.2 9.5 10.7 2.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 CBY21754.1 - 0.096 13.2 18.1 0.18 12.3 0.4 4.1 4 0 0 4 4 4 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 CBY21754.1 - 0.11 12.7 4.0 3.3 7.9 1.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 CBY21754.1 - 0.16 11.8 3.5 1.4 8.8 0.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 CBY21754.1 - 0.46 10.9 10.1 0.7 10.4 0.4 2.9 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 CBY21754.1 - 0.52 11.0 5.0 9 7.0 0.1 3.4 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 CBY21754.1 - 0.71 9.9 5.2 0.74 9.9 3.0 2.2 1 1 1 2 2 2 0 CpXC protein zf-C2H2_8 PF15909.5 CBY21754.1 - 2.1 8.7 6.6 4.5 7.6 5.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-LYAR PF08790.11 CBY21754.1 - 3 7.8 9.9 3.8 7.5 0.2 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DUF629 PF04780.12 CBY21754.1 - 4 5.9 14.9 1.4 7.4 3.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Zn_ribbon_recom PF13408.6 CBY21754.1 - 7.7 7.1 12.1 16 6.1 8.2 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Arrestin_N PF00339.29 CBY21755.1 - 1.8e-35 122.1 0.0 3.2e-33 114.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CBY21755.1 - 3.9e-26 92.1 0.2 1.1e-25 90.6 0.4 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Adeno_GP19K PF04881.13 CBY21755.1 - 0.095 12.7 0.1 0.29 11.2 0.1 1.8 2 0 0 2 2 2 0 Adenovirus GP19K DUF2393 PF09624.10 CBY21755.1 - 0.12 12.3 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Dynamin_N PF00350.23 CBY21756.1 - 3.9e-31 108.4 0.0 1.9e-30 106.2 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 CBY21756.1 - 3.6e-07 29.7 0.5 3.6e-07 29.7 0.5 2.9 3 1 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 CBY21756.1 - 3.3e-05 24.0 0.0 0.00027 21.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY21756.1 - 0.019 15.4 0.2 0.097 13.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 CBY21756.1 - 0.037 14.2 1.4 0.87 9.8 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase CLZ PF16526.5 CBY21756.1 - 8.1 6.9 8.2 1.3 9.4 0.9 3.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Aldo_ket_red PF00248.21 CBY21757.1 - 1.4e-39 136.0 0.0 2.8e-39 135.1 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family TIR PF01582.20 CBY21757.1 - 0.02 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 TIR domain WD40 PF00400.32 CBY21758.1 - 2.8e-31 107.0 7.3 9.3e-06 26.3 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21758.1 - 5e-08 33.1 0.1 0.14 12.5 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY21758.1 - 0.035 12.8 0.1 2.8 6.5 0.0 3.2 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 CBY21758.1 - 0.067 12.5 0.0 9.5 5.4 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain eIF2A PF08662.11 CBY21758.1 - 0.13 12.1 0.8 35 4.2 0.0 3.8 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A SPT2 PF08243.11 CBY21758.1 - 0.66 10.5 6.1 1.4 9.5 6.1 1.5 1 0 0 1 1 1 0 SPT2 chromatin protein DUF778 PF05608.12 CBY21759.1 - 1.1e-41 143.3 4.8 2.4e-22 80.2 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 CBY21759.1 - 0.014 15.0 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Peptidase_C97 PF05903.14 CBY21759.1 - 0.043 13.7 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 PPPDE putative peptidase domain UbiA PF01040.18 CBY21760.1 - 1.4e-29 103.1 5.5 2e-29 102.6 5.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Sec6 PF06046.13 CBY21761.1 - 3.6e-91 306.3 0.1 7.7e-91 305.2 0.0 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 Focal_AT PF03623.13 CBY21761.1 - 0.032 14.2 4.2 0.81 9.7 1.3 3.4 4 0 0 4 4 4 0 Focal adhesion targeting region Dynactin_p22 PF07426.11 CBY21761.1 - 3 7.7 8.2 0.92 9.3 4.6 2.1 2 1 0 2 2 2 0 Dynactin subunit p22 MCM6_C PF18263.1 CBY21761.1 - 3.9 7.8 6.0 14 5.9 2.3 3.1 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain SOAR PF16533.5 CBY21761.1 - 7.7 6.6 7.8 1.6 8.7 1.4 3.0 3 0 0 3 3 3 0 STIM1 Orai1-activating region DZF PF07528.14 CBY21762.1 - 4.5e-37 128.0 0.0 3.1e-36 125.3 0.0 1.9 1 1 0 1 1 1 1 DZF domain DUF3450 PF11932.8 CBY21762.1 - 0.066 12.5 0.1 0.095 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HBS1_N PF08938.10 CBY21762.1 - 0.13 12.6 0.1 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 HBS1 N-terminus PAP_assoc PF03828.19 CBY21763.1 - 1.1e-07 32.0 0.2 2.7e-07 30.7 0.2 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY21763.1 - 1.1e-05 25.6 0.0 5.2e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBY21763.1 - 0.0081 16.2 0.1 0.051 13.7 0.0 2.3 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Arylsulfotran_N PF17425.2 CBY21763.1 - 0.091 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain Presenilin PF01080.17 CBY21765.1 - 3 6.5 8.7 0.09 11.5 2.7 1.5 2 0 0 2 2 2 0 Presenilin LMBR1 PF04791.16 CBY21765.1 - 3.3 6.5 4.2 5.3 5.8 4.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Chitin_synth_2 PF03142.15 CBY21766.1 - 7.2e-28 97.5 4.3 9.4e-25 87.2 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CBY21766.1 - 6.6e-10 39.2 6.1 4e-09 36.7 5.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CBY21766.1 - 2.9e-09 37.2 0.0 6.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CitMHS PF03600.16 CBY21766.1 - 0.011 15.0 1.2 0.033 13.4 1.5 1.6 2 0 0 2 2 2 0 Citrate transporter Glycos_transf_2 PF00535.26 CBY21766.1 - 0.052 13.4 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 SUZ-C PF12901.7 CBY21767.1 - 0.0028 17.6 0.1 0.0052 16.8 0.1 1.4 1 0 0 1 1 1 1 SUZ-C motif La PF05383.17 CBY21768.1 - 4.2e-11 42.7 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY21768.1 - 0.0025 17.6 0.0 2.8 7.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calpain_inhib PF00748.19 CBY21769.1 - 0.037 14.5 3.2 0.069 13.6 3.2 1.3 1 0 0 1 1 1 0 Calpain inhibitor DUF515 PF04415.12 CBY21769.1 - 0.74 8.1 3.8 1.2 7.5 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Phospholip_A2_1 PF00068.19 CBY21770.1 - 1.7e-10 41.3 4.7 3.2e-10 40.4 4.7 1.4 1 0 0 1 1 1 1 Phospholipase A2 Neur_chan_LBD PF02931.23 CBY21771.1 - 3.5e-31 108.3 0.1 5.1e-31 107.8 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain I-set PF07679.16 CBY21772.1 - 5.7e-81 266.7 0.2 4.4e-17 61.9 0.0 8.3 8 1 0 8 8 8 7 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY21772.1 - 2.2e-50 169.2 0.0 2.5e-13 50.4 0.0 7.5 7 0 0 7 7 7 7 Immunoglobulin domain fn3 PF00041.21 CBY21772.1 - 3.7e-34 116.9 0.0 2.7e-11 43.7 0.0 4.1 4 0 0 4 4 3 3 Fibronectin type III domain ig PF00047.25 CBY21772.1 - 1.1e-26 92.9 0.7 5.8e-08 32.8 0.0 7.7 7 1 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 CBY21772.1 - 1e-23 83.6 0.0 0.00052 20.2 0.0 7.6 7 2 1 8 8 8 4 Immunoglobulin V-set domain Ig_2 PF13895.6 CBY21772.1 - 4.3e-22 78.2 0.3 5.2e-09 36.3 0.0 7.5 7 1 0 7 7 7 4 Immunoglobulin domain THB PF18362.1 CBY21772.1 - 5.1e-08 32.4 4.2 6.9e-08 32.0 0.4 2.4 2 0 0 2 2 2 1 Tri-helix bundle domain Pur_ac_phosph_N PF16656.5 CBY21772.1 - 1.7e-05 25.3 0.0 0.14 12.8 0.0 3.9 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 CBY21772.1 - 0.0012 18.4 0.0 0.36 10.4 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin domain Receptor_2B4 PF11465.8 CBY21772.1 - 0.0019 18.4 0.0 0.36 11.1 0.0 3.7 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 CBY21772.1 - 0.011 15.8 0.3 1.7 8.7 0.0 4.3 6 0 0 6 6 5 0 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 CBY21772.1 - 0.019 15.0 3.6 12 6.0 0.0 4.6 6 0 0 6 6 6 0 CD80-like C2-set immunoglobulin domain Herpes_gI PF01688.17 CBY21772.1 - 0.039 13.9 0.2 43 4.0 0.0 4.2 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein I MG2 PF01835.19 CBY21772.1 - 0.16 12.4 0.0 13 6.4 0.0 3.7 3 0 0 3 3 3 0 MG2 domain Glyco_transf_41 PF13844.6 CBY21773.1 - 1.1e-232 772.6 0.1 6.1e-232 770.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 41 TPR_1 PF00515.28 CBY21773.1 - 6.5e-89 288.5 28.8 4e-09 35.9 0.2 13.1 14 0 0 14 14 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 CBY21773.1 - 2.8e-76 250.9 33.5 1.4e-11 43.9 0.6 14.3 7 4 8 15 15 14 11 TPR repeat TPR_8 PF13181.6 CBY21773.1 - 2.1e-60 195.9 13.7 5.3e-06 26.2 0.1 13.7 14 0 0 14 14 13 10 Tetratricopeptide repeat TPR_2 PF07719.17 CBY21773.1 - 2.2e-59 192.9 28.9 4.6e-06 26.3 0.0 13.9 15 0 0 15 15 13 11 Tetratricopeptide repeat TPR_17 PF13431.6 CBY21773.1 - 1.7e-54 178.3 31.6 1.7e-05 24.9 0.2 13.7 14 0 0 14 14 13 9 Tetratricopeptide repeat TPR_7 PF13176.6 CBY21773.1 - 1e-47 156.7 16.1 8.3e-05 22.3 0.0 12.6 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_12 PF13424.6 CBY21773.1 - 2.4e-43 146.3 31.4 3.7e-10 40.0 0.5 9.2 4 4 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 CBY21773.1 - 1.3e-38 131.3 9.5 4.7e-09 36.7 0.3 8.4 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_10 PF13374.6 CBY21773.1 - 1.4e-38 129.7 38.6 9.5e-06 25.3 1.1 12.5 11 1 1 12 12 12 9 Tetratricopeptide repeat TPR_19 PF14559.6 CBY21773.1 - 2.1e-37 127.4 17.0 1.8e-06 28.3 0.1 8.2 5 2 3 8 8 7 7 Tetratricopeptide repeat TPR_14 PF13428.6 CBY21773.1 - 5.2e-37 123.4 8.3 0.00044 20.8 0.0 11.9 3 2 8 11 11 11 8 Tetratricopeptide repeat TPR_9 PF13371.6 CBY21773.1 - 1.5e-18 66.7 4.9 0.019 15.1 0.6 7.1 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 CBY21773.1 - 3.8e-15 55.4 17.4 0.27 11.9 0.1 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat NARP1 PF12569.8 CBY21773.1 - 3e-13 49.5 4.8 0.0011 17.9 0.0 4.9 1 1 0 4 4 4 3 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 CBY21773.1 - 1.8e-10 40.7 9.7 0.19 11.0 0.1 5.3 1 1 3 4 4 4 4 MalT-like TPR region TPR_4 PF07721.14 CBY21773.1 - 2.1e-10 40.2 0.0 0.69 10.7 0.0 7.0 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY21773.1 - 2.4e-09 36.8 6.9 1.9e-05 24.1 1.5 4.9 1 1 1 3 3 3 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 CBY21773.1 - 3.5e-08 33.3 13.3 0.00091 18.8 0.4 4.1 4 1 0 4 4 4 3 Est1 DNA/RNA binding domain TPR_3 PF07720.12 CBY21773.1 - 5.3e-08 32.7 1.6 0.38 10.8 0.0 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY21773.1 - 7.6e-07 29.3 15.2 0.00054 20.1 2.0 5.6 5 1 1 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.23 CBY21773.1 - 1.5e-05 24.4 4.5 0.23 10.6 1.8 4.3 2 2 0 2 2 2 2 FAT domain TPR_20 PF14561.6 CBY21773.1 - 0.0002 21.7 8.2 0.34 11.2 0.7 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.6 CBY21773.1 - 0.00035 20.1 19.8 0.92 8.9 0.2 5.3 1 1 3 5 5 5 3 Soluble NSF attachment protein, SNAP TOM20_plant PF06552.12 CBY21773.1 - 0.00082 19.2 1.9 53 3.5 0.1 5.5 3 2 3 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 Wzy_C_2 PF11846.8 CBY21773.1 - 0.0028 17.6 5.0 0.0052 16.7 1.1 3.2 2 1 2 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal AAA_13 PF13166.6 CBY21773.1 - 0.0028 16.4 1.1 0.0044 15.8 1.1 1.2 1 0 0 1 1 1 1 AAA domain DUF4810 PF16068.5 CBY21773.1 - 0.0079 16.7 3.8 12 6.6 0.1 6.4 6 1 1 7 7 6 0 Domain of unknown function (DUF4810) DUF4807 PF16065.5 CBY21773.1 - 0.024 14.3 0.1 0.87 9.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4807) DUF627 PF04781.12 CBY21773.1 - 0.05 13.6 5.3 39 4.3 0.1 5.1 5 0 0 5 5 4 0 Protein of unknown function (DUF627) TPR_21 PF09976.9 CBY21773.1 - 0.063 13.0 11.5 2.3 7.9 1.9 4.7 2 2 1 4 4 4 0 Tetratricopeptide repeat-like domain Alkyl_sulf_dimr PF14863.6 CBY21773.1 - 0.073 13.5 1.3 25 5.3 0.1 3.5 2 2 1 4 4 4 0 Alkyl sulfatase dimerisation BTAD PF03704.17 CBY21773.1 - 0.079 13.4 10.1 0.065 13.7 1.3 4.3 2 2 1 4 4 4 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 CBY21773.1 - 0.091 12.2 1.7 31 4.1 0.0 5.3 6 0 0 6 6 6 0 SHNi-TPR SUKH_5 PF14567.6 CBY21773.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Coatomer_E PF04733.14 CBY21773.1 - 0.15 11.5 3.6 9.9 5.5 0.1 3.5 2 1 1 4 4 3 0 Coatomer epsilon subunit MIT PF04212.18 CBY21773.1 - 0.18 11.9 23.5 4 7.6 0.0 8.9 9 2 2 11 11 10 0 MIT (microtubule interacting and transport) domain Mad3_BUB1_I PF08311.12 CBY21773.1 - 1.2 9.2 13.4 2.2 8.3 0.6 5.6 6 1 0 6 6 5 0 Mad3/BUB1 homology region 1 DUF5113 PF17140.4 CBY21773.1 - 6.4 6.6 15.6 33 4.2 0.2 6.1 3 3 3 7 7 7 0 Domain of unknown function (DUF5113) SNAP-25 PF00835.19 CBY21774.1 - 2.6e-21 75.7 3.5 5.5e-21 74.6 3.5 1.6 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.8 CBY21774.1 - 7.5e-05 22.9 4.9 0.016 15.5 0.4 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 CBY21774.1 - 0.00021 21.2 6.8 0.00073 19.5 6.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) FliJ PF02050.16 CBY21774.1 - 0.02 15.1 3.9 1.5 9.0 0.2 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Laminin_II PF06009.12 CBY21774.1 - 0.13 12.3 7.6 2.3 8.2 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II ABC_membrane PF00664.23 CBY21774.1 - 0.13 11.9 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 ABC transporter transmembrane region Rx_N PF18052.1 CBY21774.1 - 0.19 12.0 4.7 0.4 11.0 0.1 2.8 2 1 1 3 3 3 0 Rx N-terminal domain Sec20 PF03908.13 CBY21774.1 - 0.21 11.5 2.3 0.55 10.2 0.2 2.2 2 0 0 2 2 2 0 Sec20 DUF1664 PF07889.12 CBY21774.1 - 0.23 11.5 7.0 3.1 7.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 CBY21774.1 - 0.24 11.5 2.9 0.68 10.0 2.9 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 CBY21774.1 - 0.3 11.4 3.4 1.7 9.0 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein Golgin_A5 PF09787.9 CBY21774.1 - 0.38 10.2 7.2 2.1 7.7 0.3 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 Snapin_Pallidin PF14712.6 CBY21774.1 - 0.43 11.0 7.6 3.1 8.3 0.8 2.3 2 0 0 2 2 2 0 Snapin/Pallidin HisKA_3 PF07730.13 CBY21774.1 - 0.94 10.1 6.1 9.3 6.9 0.3 3.4 3 1 1 4 4 4 0 Histidine kinase FlaC_arch PF05377.11 CBY21774.1 - 1.1 9.7 6.7 5.3 7.5 1.8 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 CBY21774.1 - 1.3 9.7 6.4 4.3 8.0 0.3 2.8 2 1 1 3 3 3 0 SlyX MscS_porin PF12795.7 CBY21774.1 - 2.4 7.7 9.5 1.4 8.4 1.4 2.4 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain XhlA PF10779.9 CBY21774.1 - 4.4 7.6 9.8 20 5.5 1.1 3.5 2 2 2 4 4 4 0 Haemolysin XhlA DUF16 PF01519.16 CBY21774.1 - 4.9 7.7 8.4 17 6.0 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF948 PF06103.11 CBY21774.1 - 6.2 7.1 7.6 14 6.0 0.9 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SNARE PF05739.19 CBY21774.1 - 9.4 6.3 8.0 0.88 9.6 0.6 2.5 3 0 0 3 3 2 0 SNARE domain Phenyl_P_gamma PF09662.10 CBY21775.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) RNase_T PF00929.24 CBY21776.1 - 6.6e-15 56.0 0.2 2.4e-14 54.2 0.2 2.0 1 1 0 1 1 1 1 Exonuclease Dynamin_M PF01031.20 CBY21778.1 - 7.8e-94 314.1 0.0 1.1e-93 313.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CBY21778.1 - 1.4e-50 171.7 0.0 2.2e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBY21778.1 - 0.00016 21.7 0.0 0.00039 20.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBY21778.1 - 0.19 12.0 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Cullin_Nedd8 PF10557.9 CBY21778.1 - 1.7 8.7 4.1 20 5.3 0.1 3.1 1 1 1 2 2 2 0 Cullin protein neddylation domain MCD PF05292.11 CBY21779.1 - 1.1e-55 189.1 0.0 1.6e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain RGI1 PF10843.8 CBY21779.1 - 0.12 12.0 0.1 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Respiratory growth induced protein 1 SAM_1 PF00536.30 CBY21780.1 - 1.1e-09 38.6 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY21780.1 - 4.3e-09 36.4 0.0 7.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CBY21780.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf_Rg PF17915.1 CBY21780.1 - 0.045 13.1 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Reverse gyrase zinc finger SAM_3 PF18016.1 CBY21780.1 - 0.059 13.2 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1828 PF08861.10 CBY21780.1 - 0.15 12.4 0.1 10 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF1828 NOD2_WH PF17779.1 CBY21780.1 - 0.16 12.3 0.1 1.1 9.7 0.1 2.2 2 0 0 2 2 2 0 NOD2 winged helix domain DUF996 PF06195.13 CBY21781.1 - 0.12 12.7 5.2 7.8 6.8 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF996) CUB PF00431.20 CBY21782.1 - 9.5e-12 45.2 0.1 1.7e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 CUB domain Ank_2 PF12796.7 CBY21784.1 - 3.8e-90 296.6 48.6 9.9e-17 61.3 4.4 15.1 7 5 10 17 17 17 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY21784.1 - 9.5e-73 239.7 34.3 1.5e-10 41.4 1.5 17.3 11 4 6 17 17 17 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY21784.1 - 8e-53 175.8 38.6 9.2e-07 29.0 2.4 17.2 13 3 4 17 17 17 12 Ankyrin repeats (many copies) Ank PF00023.30 CBY21784.1 - 6.3e-49 162.4 61.6 1.3e-05 25.4 0.1 22.2 24 0 0 24 24 24 12 Ankyrin repeat Ank_3 PF13606.6 CBY21784.1 - 1.2e-43 142.1 38.9 0.00014 22.0 0.2 24.1 27 0 0 27 27 27 10 Ankyrin repeat PARP_reg PF02877.14 CBY21784.1 - 2.4e-17 63.3 0.1 5.3e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CBY21784.1 - 3.5e-09 36.6 0.0 1.5e-08 34.6 0.0 2.2 1 0 0 1 1 1 1 WGR domain PARP PF00644.20 CBY21784.1 - 0.0012 18.5 0.1 0.0012 18.5 0.1 3.2 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Ntox24 PF15529.6 CBY21785.1 - 0.041 14.2 0.0 3.8 7.9 0.0 3.5 4 0 0 4 4 4 0 Bacterial toxin 24 DUF484 PF04340.12 CBY21785.1 - 0.18 11.5 0.0 0.76 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF484 MepB PF08877.10 CBY21787.1 - 0.093 12.4 1.1 7.2 6.3 0.1 2.4 2 0 0 2 2 2 0 MepB protein EVC2_like PF12297.8 CBY21788.1 - 0.14 10.8 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Phlebovirus_NSM PF07246.11 CBY21789.1 - 0.011 15.1 4.5 0.021 14.2 4.5 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Chorein_N PF12624.7 CBY21789.1 - 0.046 13.9 0.5 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 Med30 PF11315.8 CBY21789.1 - 8.4 6.6 13.3 1.5 9.0 8.3 2.3 2 1 0 2 2 2 0 Mediator complex subunit 30 Ribosomal_S8 PF00410.19 CBY21790.1 - 0.002 18.1 2.6 0.022 14.7 0.4 2.4 2 1 0 2 2 2 2 Ribosomal protein S8 YlbE PF14003.6 CBY21790.1 - 0.17 12.4 2.3 0.27 11.7 1.5 1.8 1 1 0 1 1 1 0 YlbE-like protein Thioredoxin_6 PF13848.6 CBY21791.1 - 2.7e-30 105.6 1.1 1.1e-29 103.6 0.2 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 CBY21791.1 - 7.6e-08 32.3 0.2 1.9e-07 31.0 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 CBY21791.1 - 0.0049 16.8 0.3 0.019 14.9 0.1 2.1 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CBY21791.1 - 0.0073 16.7 0.6 0.024 15.1 0.6 2.0 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBY21791.1 - 0.053 12.9 0.2 0.081 12.3 0.2 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glyco_transf_43 PF03360.16 CBY21791.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 43 HIP1_clath_bdg PF16515.5 CBY21792.1 - 0.0031 18.1 7.1 0.0057 17.2 7.1 1.4 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Rx_N PF18052.1 CBY21792.1 - 0.021 15.1 2.2 0.049 13.9 2.2 1.7 1 0 0 1 1 1 0 Rx N-terminal domain PRKG1_interact PF15898.5 CBY21792.1 - 0.03 15.2 5.3 0.079 13.9 5.3 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ERM PF00769.19 CBY21792.1 - 0.036 13.9 12.6 0.047 13.5 12.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_15 PF13175.6 CBY21792.1 - 0.16 11.7 4.8 0.21 11.3 4.8 1.3 1 0 0 1 1 1 0 AAA ATPase domain DELLA PF12041.8 CBY21792.1 - 0.23 11.4 1.9 6 6.8 0.0 2.9 2 1 1 3 3 3 0 Transcriptional regulator DELLA protein N terminal Spc24 PF08286.11 CBY21792.1 - 0.68 10.2 7.5 1.6 9.0 7.5 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Cob_adeno_trans PF01923.18 CBY21792.1 - 0.84 9.8 3.8 0.95 9.6 2.6 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase RP-C_C PF11800.8 CBY21792.1 - 0.93 9.6 8.4 1.6 8.8 8.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Spc7 PF08317.11 CBY21792.1 - 2.5 6.9 13.1 3.6 6.4 13.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Spc19 PF08287.11 CBY21792.1 - 4.7 7.1 12.0 3.4 7.5 9.7 1.8 2 0 0 2 2 2 0 Spc19 FapA PF03961.13 CBY21792.1 - 5.6 5.4 8.7 8.2 4.9 8.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TACC_C PF05010.14 CBY21794.1 - 0.0004 20.2 8.6 0.0004 20.2 8.6 3.7 2 1 0 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tropomyosin_1 PF12718.7 CBY21794.1 - 0.0082 16.3 11.4 0.0082 16.3 11.4 4.9 2 1 2 4 4 4 2 Tropomyosin like DUF812 PF05667.11 CBY21794.1 - 0.0094 14.9 2.0 0.0094 14.9 2.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF812) Sec34 PF04136.15 CBY21794.1 - 0.014 15.2 1.5 0.014 15.2 1.5 4.8 3 2 3 6 6 6 0 Sec34-like family bZIP_1 PF00170.21 CBY21794.1 - 0.046 13.8 1.3 0.046 13.8 1.3 7.2 4 2 2 6 6 6 0 bZIP transcription factor YvbH_ext PF11724.8 CBY21794.1 - 0.077 13.3 0.2 0.4 11.0 0.2 2.2 1 0 0 1 1 1 0 YvbH-like oligomerisation region DUF4407 PF14362.6 CBY21794.1 - 0.66 9.3 35.5 0.38 10.0 18.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 CBY21794.1 - 1 9.5 42.2 0.59 10.3 2.8 4.5 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Filament PF00038.21 CBY21794.1 - 3.6 7.1 53.4 4.5 6.8 31.4 3.6 2 2 0 2 2 2 0 Intermediate filament protein Homeodomain PF00046.29 CBY21796.1 - 1.5e-19 69.5 12.7 3.1e-19 68.5 12.7 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY21796.1 - 0.014 15.3 2.3 0.032 14.1 2.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 CBY21796.1 - 0.12 11.8 0.2 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Cast PF10174.9 CBY21797.1 - 4.8e-05 21.8 2.9 4.8e-05 21.8 2.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Laminin_I PF06008.14 CBY21797.1 - 0.0054 16.5 1.5 0.0061 16.3 1.5 1.1 1 0 0 1 1 1 1 Laminin Domain I Ribonuc_2-5A PF06479.12 CBY21797.1 - 0.017 15.3 0.4 0.019 15.1 0.4 1.1 1 0 0 1 1 1 0 Ribonuclease 2-5A DGF-1_C PF11040.8 CBY21797.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus CLCA PF08434.11 CBY21798.1 - 7.3e-13 48.5 6.4 1.8e-07 30.8 0.4 3.0 1 1 1 2 2 2 2 Calcium-activated chloride channel N terminal MAP17 PF15807.5 CBY21798.1 - 1.4 9.1 12.8 0.2 11.9 1.2 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Ctr PF04145.15 CBY21798.1 - 3.1 8.4 9.1 73 4.0 8.7 2.6 1 1 0 1 1 1 0 Ctr copper transporter family FAM176 PF14851.6 CBY21798.1 - 3.1 7.5 8.2 2.4 7.8 0.6 2.5 2 0 0 2 2 2 0 FAM176 family COesterase PF00135.28 CBY21799.1 - 1.1e-102 344.6 1.9 1.6e-54 185.6 0.6 2.1 2 0 0 2 2 2 2 Carboxylesterase family Zona_pellucida PF00100.23 CBY21799.1 - 1.3e-17 64.4 3.3 2.7e-17 63.4 3.3 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Glyco_transf_4 PF13439.6 CBY21799.1 - 0.047 13.7 0.0 2.1 8.3 0.0 2.9 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Ig_3 PF13927.6 CBY21800.1 - 1e-07 32.5 7.8 0.016 15.8 0.3 6.3 5 2 0 5 5 5 1 Immunoglobulin domain Ig_2 PF13895.6 CBY21800.1 - 7.8e-06 26.1 2.3 2.1 8.7 0.1 4.7 3 1 1 4 4 4 2 Immunoglobulin domain I-set PF07679.16 CBY21800.1 - 7e-05 22.8 0.9 11 6.2 0.0 6.0 6 1 0 7 7 7 1 Immunoglobulin I-set domain C1-set PF07654.15 CBY21800.1 - 0.0006 20.1 0.6 15 6.0 0.1 3.8 3 0 0 3 3 3 2 Immunoglobulin C1-set domain Ig_4 PF16680.5 CBY21800.1 - 0.038 14.2 0.3 3.5 7.9 0.0 3.5 4 0 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain PK PF00224.21 CBY21800.1 - 0.061 12.2 0.1 0.097 11.5 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF4073 PF13285.6 CBY21800.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Trypsin PF00089.26 CBY21801.1 - 3.5e-42 144.7 0.1 5.6e-42 144.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY21801.1 - 0.00093 20.1 0.0 0.002 19.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain TSP_1 PF00090.19 CBY21801.1 - 0.0012 19.0 2.7 0.0012 19.0 2.7 3.4 4 0 0 4 4 4 1 Thrombospondin type 1 domain Trefoil PF00088.18 CBY21801.1 - 0.013 15.4 8.2 0.013 15.4 8.2 3.6 3 0 0 3 3 3 0 Trefoil (P-type) domain CD20 PF04103.15 CBY21802.1 - 0.066 13.3 2.2 0.072 13.2 0.1 1.9 2 0 0 2 2 2 0 CD20-like family DUF308 PF03729.13 CBY21802.1 - 0.12 12.7 5.0 0.17 12.2 5.0 1.2 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) COPI_assoc PF08507.10 CBY21802.1 - 0.21 11.7 2.5 6.6 6.8 2.5 2.2 1 1 0 1 1 1 0 COPI associated protein MAR_sialic_bdg PF10564.9 CBY21803.1 - 1.7e-165 537.6 43.8 2.5e-19 69.1 0.2 10.2 10 0 0 10 10 10 10 Sialic-acid binding micronemal adhesive repeat CCDC23 PF15674.5 CBY21803.1 - 3.7e-05 23.6 8.3 17 5.5 0.3 8.0 9 0 0 9 9 9 2 Coiled-coil domain-containing protein 23 EF-hand_9 PF14658.6 CBY21803.1 - 0.044 14.1 0.0 8 6.9 0.0 4.2 4 0 0 4 4 4 0 EF-hand domain Mucin PF01456.17 CBY21803.1 - 0.05 13.6 24.2 0.041 13.9 7.1 2.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Frigida PF07899.11 CBY21803.1 - 0.23 10.7 3.4 17 4.5 0.0 4.9 7 0 0 7 7 7 0 Frigida-like protein Trypsin PF00089.26 CBY21804.1 - 1.5e-12 47.8 0.3 1.9e-12 47.5 0.3 1.1 1 0 0 1 1 1 1 Trypsin Gal-3-0_sulfotr PF06990.11 CBY21805.1 - 4.2e-26 91.8 3.3 5.5e-26 91.4 1.2 2.1 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 CBY21805.1 - 8.4e-10 38.6 9.0 8.8e-08 31.9 2.5 3.8 2 2 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY21805.1 - 1.2e-06 29.1 1.5 0.001 19.5 0.1 3.5 2 1 0 3 3 3 1 Sulfotransferase family zf-HC5HC2H_2 PF13832.6 CBY21808.1 - 7.7e-34 116.2 11.0 7.7e-34 116.2 11.0 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBY21808.1 - 3.7e-26 91.2 6.2 3.7e-26 91.2 6.2 2.8 3 0 0 3 3 2 1 PHD-like zinc-binding domain Bromodomain PF00439.25 CBY21808.1 - 1.9e-20 72.7 0.5 7.4e-20 70.8 0.5 2.1 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 CBY21808.1 - 2.3e-14 52.6 2.4 2.3e-14 52.6 2.4 2.8 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 CBY21808.1 - 2.2e-10 40.8 0.0 3.2e-09 37.1 0.0 3.1 2 0 0 2 2 2 1 PWWP domain EPL1 PF10513.9 CBY21808.1 - 5.6e-10 39.8 2.0 5.6e-10 39.8 2.0 3.4 3 1 0 3 3 2 1 Enhancer of polycomb-like PHD PF00628.29 CBY21808.1 - 1.8e-07 30.9 4.9 1.8e-07 30.9 4.9 3.8 4 0 0 4 4 4 2 PHD-finger zf-C2H2 PF00096.26 CBY21808.1 - 0.0022 18.4 0.1 0.0022 18.4 0.1 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type Glyco_hydro_38N PF01074.22 CBY21808.1 - 0.073 12.4 0.1 8.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 N-terminal domain zf-C2H2_4 PF13894.6 CBY21808.1 - 0.57 11.2 0.1 0.57 11.2 0.1 3.5 5 0 0 5 5 3 0 C2H2-type zinc finger ADK_lid PF05191.14 CBY21808.1 - 0.97 9.5 5.7 0.5 10.4 1.5 2.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RING-like PF08746.11 CBY21808.1 - 9.1 6.7 19.1 1.1 9.6 7.0 3.1 2 0 0 2 2 2 0 RING-like domain Hydrolase_4 PF12146.8 CBY21810.1 - 4.2e-30 104.8 0.0 5.3e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY21810.1 - 3.9e-05 23.4 0.0 5.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY21810.1 - 0.0019 18.8 0.0 0.0023 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CBY21810.1 - 0.0055 16.4 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 CBY21810.1 - 0.088 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Ndr family BIV_Env PF05858.12 CBY21810.1 - 0.13 10.4 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) LIDHydrolase PF10230.9 CBY21810.1 - 0.16 11.5 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Na_K-ATPase PF00287.18 CBY21811.1 - 3.8e-54 183.8 0.0 1.2e-28 100.2 0.0 2.1 1 1 1 2 2 2 2 Sodium / potassium ATPase beta chain Neur_chan_memb PF02932.16 CBY21812.1 - 1.2e-64 218.6 21.7 1.6e-53 182.3 17.4 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY21812.1 - 2.3e-55 187.4 1.0 2.9e-55 187.0 1.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 CBY21813.1 - 0.024 14.1 0.0 0.026 14.0 0.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain Transposase_21 PF02992.14 CBY21814.1 - 0.19 10.9 1.3 0.24 10.6 0.4 1.5 2 0 0 2 2 2 0 Transposase family tnp2 MORN PF02493.20 CBY21815.1 - 4.7e-13 48.2 14.4 2.6e-05 23.8 0.9 5.4 5 0 0 5 5 5 4 MORN repeat SM-ATX PF14438.6 CBY21815.1 - 0.031 14.4 0.1 3.4 7.9 0.1 2.5 1 1 1 2 2 2 0 Ataxin 2 SM domain MIG-14_Wnt-bd PF06664.12 CBY21816.1 - 0.00065 19.0 4.3 0.00065 19.0 4.3 1.5 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion MLANA PF14991.6 CBY21816.1 - 0.021 15.1 0.4 0.069 13.4 0.0 2.0 3 0 0 3 3 3 0 Protein melan-A DUF3961 PF13106.6 CBY21816.1 - 0.18 11.5 3.4 0.61 9.8 3.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Synaptobrevin PF00957.21 CBY21816.1 - 0.21 11.4 1.3 6.9 6.5 0.3 2.6 2 0 0 2 2 2 0 Synaptobrevin DUF2207 PF09972.9 CBY21816.1 - 0.26 10.0 4.3 1.1 8.0 0.9 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) UPF0114 PF03350.16 CBY21816.1 - 0.43 10.8 5.2 1.9 8.7 0.0 3.1 3 1 0 3 3 3 0 Uncharacterized protein family, UPF0114 Pho86 PF11124.8 CBY21816.1 - 0.49 9.8 3.4 1.1 8.7 3.4 1.5 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DHHC PF01529.20 CBY21816.1 - 2.5 8.2 14.9 29 4.8 8.3 3.1 1 1 0 2 2 2 0 DHHC palmitoyltransferase Nup35_RRM PF05172.13 CBY21817.1 - 8.6e-11 41.7 0.2 2.9e-10 40.0 0.2 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CBY21817.1 - 2.3e-06 27.5 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CBY21817.1 - 0.0074 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3284 PF11687.8 CBY21817.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) WD40 PF00400.32 CBY21818.1 - 2.2e-24 85.3 4.6 0.0041 17.9 0.0 10.4 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21818.1 - 1e-05 25.8 0.1 2.2 8.6 0.0 6.3 4 2 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain KASH_CCD PF14662.6 CBY21818.1 - 0.0011 18.8 28.4 0.0011 18.8 28.4 5.1 1 1 4 5 5 5 2 Coiled-coil region of CCDC155 or KASH PQQ_2 PF13360.6 CBY21818.1 - 0.0066 16.1 0.4 3.9 7.0 0.1 2.6 2 0 0 2 2 2 2 PQQ-like domain TMF_DNA_bd PF12329.8 CBY21818.1 - 0.0069 16.4 17.1 0.0069 16.4 17.1 8.7 3 1 7 10 10 10 3 TATA element modulatory factor 1 DNA binding PD40 PF07676.12 CBY21818.1 - 0.2 11.7 0.0 41 4.3 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat CSD PF00313.22 CBY21820.1 - 9.2e-10 38.2 0.5 1.8e-09 37.3 0.5 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain LolA PF03548.15 CBY21820.1 - 0.0025 17.5 0.1 0.023 14.4 0.2 2.4 2 0 0 2 2 2 1 Outer membrane lipoprotein carrier protein LolA zf-CpG_bind_C PF12269.8 CBY21821.1 - 0.26 11.1 2.8 0.24 11.1 0.8 1.9 2 1 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF2540 PF10802.8 CBY21821.1 - 0.38 10.9 4.0 1.6 8.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) Hc1 PF07432.13 CBY21821.1 - 0.45 10.9 4.5 5.3 7.4 0.4 2.5 1 1 1 2 2 2 0 Histone H1-like protein Hc1 zf-C2H2 PF00096.26 CBY21824.1 - 3.6e-11 42.9 20.6 6.7e-05 23.1 0.7 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY21824.1 - 6.6e-11 42.1 1.7 4.2e-06 26.9 0.1 4.6 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY21824.1 - 1.3e-10 41.2 14.6 0.00097 19.8 2.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBY21824.1 - 0.00066 19.9 1.7 0.00066 19.9 1.7 2.2 1 1 2 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CBY21824.1 - 0.12 12.7 12.7 0.9 9.9 0.2 3.3 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CBY21824.1 - 0.68 9.8 5.7 14 5.5 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HE PF16278.5 CBY21824.1 - 0.74 10.3 6.9 47 4.5 6.9 2.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 CBY21825.1 - 3.4e-11 43.0 20.6 6.3e-05 23.2 0.7 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY21825.1 - 5.6e-11 42.4 1.7 4e-06 27.0 0.1 4.5 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY21825.1 - 1.2e-10 41.2 14.6 0.00092 19.9 2.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBY21825.1 - 0.00032 21.0 3.1 0.00057 20.1 1.6 2.1 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CBY21825.1 - 0.075 13.4 11.9 0.12 12.8 4.5 3.2 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CBY21825.1 - 0.58 10.0 5.7 13 5.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HE PF16278.5 CBY21825.1 - 0.68 10.4 7.0 46 4.6 7.0 2.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger CDC37_M PF08565.11 CBY21826.1 - 5.8e-27 94.0 0.8 1.4e-26 92.7 0.8 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 CBY21826.1 - 2.4e-12 47.9 15.2 2.4e-12 47.9 15.2 2.6 1 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 CBY21826.1 - 5.1e-09 36.2 0.0 5.1e-09 36.2 0.0 3.2 2 1 0 2 2 2 1 Cdc37 C terminal domain CPSase_L_D3 PF02787.19 CBY21826.1 - 0.0016 18.7 3.1 0.0043 17.4 3.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Ribonuc_red_2_N PF08471.10 CBY21826.1 - 0.018 15.2 0.7 0.018 15.2 0.7 3.2 3 1 1 4 4 4 0 Class II vitamin B12-dependent ribonucleotide reductase PBD PF00786.28 CBY21826.1 - 0.11 12.9 1.2 0.36 11.2 0.0 2.5 2 0 0 2 2 2 0 P21-Rho-binding domain FoP_duplication PF13865.6 CBY21826.1 - 0.63 10.6 4.7 5.8 7.6 0.0 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 LMBR1 PF04791.16 CBY21826.1 - 7.3 5.4 7.9 9 5.1 7.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Rdx PF10262.9 CBY21827.1 - 0.00045 20.4 0.0 0.00057 20.0 0.0 1.1 1 0 0 1 1 1 1 Rdx family Med26 PF08711.11 CBY21829.1 - 8.4e-13 48.1 0.2 2.3e-12 46.7 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RDD PF06271.12 CBY21831.1 - 2.4e-11 44.0 8.0 5e-09 36.5 8.0 2.8 1 1 0 1 1 1 1 RDD family DUF4765 PF15962.5 CBY21831.1 - 0.017 13.1 0.1 0.023 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4765) TPR_19 PF14559.6 CBY21832.1 - 0.003 18.1 0.3 0.03 14.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SIL1 PF16782.5 CBY21833.1 - 0.043 13.0 0.3 0.084 12.1 0.3 1.4 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 RFX_DNA_binding PF02257.15 CBY21833.1 - 0.077 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain ABC_tran PF00005.27 CBY21834.1 - 1.2e-48 165.1 0.1 3.6e-27 95.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 CBY21834.1 - 4.5e-45 154.3 43.7 3.2e-34 118.6 12.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBY21834.1 - 7.2e-21 75.3 0.0 1.4e-09 38.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CBY21834.1 - 9.5e-06 26.3 1.2 0.011 16.4 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) ABC2_membrane_2 PF12679.7 CBY21834.1 - 0.00035 19.9 4.7 0.00035 19.9 4.7 2.4 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 CBY21834.1 - 0.068 13.7 0.1 0.068 13.7 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 CBY21834.1 - 0.075 12.7 11.6 1.2 8.8 0.0 4.4 5 0 0 5 5 5 0 AAA ATPase domain SRP54 PF00448.22 CBY21834.1 - 0.084 12.5 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 CBY21834.1 - 0.1 12.5 0.2 0.31 10.9 0.2 1.8 1 0 0 1 1 1 0 RsgA GTPase ATG16 PF08614.11 CBY21835.1 - 2.4e-06 27.9 99.4 0.1 12.8 21.6 5.3 2 1 3 5 5 5 4 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 CBY21835.1 - 0.00057 20.3 22.9 0.00057 20.3 22.9 4.4 2 1 1 5 5 5 1 Bacterial type III secretion protein (HrpB7) Golgin_A5 PF09787.9 CBY21835.1 - 0.0074 15.8 21.9 0.0074 15.8 21.9 3.8 1 1 2 3 3 3 2 Golgin subfamily A member 5 Spc7 PF08317.11 CBY21835.1 - 0.19 10.6 85.5 0.41 9.5 17.0 4.4 1 1 3 4 4 4 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 CBY21835.1 - 0.25 10.9 75.2 0.53 9.8 11.0 4.2 2 2 2 4 4 4 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 CBY21835.1 - 1.4 8.7 88.4 0.18 11.6 19.2 4.3 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 CBY21835.1 - 2.4 8.8 72.0 0.12 13.0 6.4 7.3 1 1 6 8 8 8 0 Initiation control protein YabA APG6_N PF17675.1 CBY21835.1 - 3.3 8.2 98.2 1.6 9.2 21.0 5.2 2 1 2 5 5 5 0 Apg6 coiled-coil region ERM PF00769.19 CBY21835.1 - 5.1 6.8 99.6 6.7 6.4 14.3 4.6 1 1 2 3 3 3 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 CBY21835.1 - 7.2 6.7 92.6 1.2 9.2 24.8 5.8 2 1 4 6 6 6 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 CBY21835.1 - 9 6.7 85.4 1.3 9.4 26.5 3.4 1 1 2 3 3 3 0 Fez1 zf-RING_5 PF14634.6 CBY21836.1 - 1.7e-08 34.3 13.8 3e-08 33.5 13.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY21836.1 - 0.0013 19.0 15.4 0.0014 18.9 13.7 1.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY21836.1 - 0.0013 18.5 13.5 0.012 15.5 14.5 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY21836.1 - 0.0017 18.3 8.3 0.05 13.6 4.5 2.3 2 0 0 2 2 2 2 RING-type zinc-finger MIEAP PF16026.5 CBY21836.1 - 0.07 13.3 1.5 0.079 13.2 1.5 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein zf-C3HC4_2 PF13923.6 CBY21836.1 - 0.074 12.9 13.7 1.4 8.9 10.8 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) His_Phos_1 PF00300.22 CBY21836.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) zf-RING_6 PF14835.6 CBY21836.1 - 0.4 10.6 9.3 1.1 9.2 9.3 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein CID_GANP PF16766.5 CBY21836.1 - 1.3 9.2 11.2 0.59 10.4 0.4 2.3 1 1 1 2 2 2 0 Binding region of GANP to ENY2 zf-RING_11 PF17123.5 CBY21836.1 - 3.9 7.3 13.3 21 5.0 0.0 2.6 2 0 0 2 2 2 0 RING-like zinc finger Orf78 PF06024.12 CBY21837.1 - 0.3 11.4 1.8 3.8 7.9 0.3 2.9 3 0 0 3 3 3 0 Orf78 (ac78) DUF4220 PF13968.6 CBY21837.1 - 0.42 10.0 7.6 0.09 12.2 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) SieB PF14163.6 CBY21837.1 - 1.8 8.0 4.7 1.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B EF-hand_6 PF13405.6 CBY21838.1 - 8.5e-09 34.7 2.6 0.0023 17.7 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY21838.1 - 2.4e-08 34.3 0.5 0.0064 16.9 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY21838.1 - 1.9e-07 30.2 0.7 0.0037 16.7 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 CBY21838.1 - 0.00035 19.9 1.1 0.22 11.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY21838.1 - 0.0067 16.3 1.2 2.5 8.0 0.0 3.2 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CBY21838.1 - 0.1 12.9 0.0 3.7 7.9 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain EGF_CA PF07645.15 CBY21840.1 - 1.8e-28 98.4 46.5 1.1e-10 41.5 9.3 4.4 3 1 1 4 4 4 3 Calcium-binding EGF domain EGF_3 PF12947.7 CBY21840.1 - 8.2e-17 61.1 44.5 1.3e-06 28.5 7.1 4.4 4 0 0 4 4 4 3 EGF domain EGF PF00008.27 CBY21840.1 - 1e-13 51.3 39.2 0.00052 20.2 3.4 4.5 4 0 0 4 4 4 4 EGF-like domain fn3 PF00041.21 CBY21840.1 - 8e-10 38.9 0.1 8.9e-05 22.8 0.0 2.8 2 1 0 2 2 2 2 Fibronectin type III domain SEA PF01390.20 CBY21840.1 - 1.9e-07 31.1 10.0 0.0065 16.5 0.1 3.8 4 0 0 4 4 4 3 SEA domain EGF_MSP1_1 PF12946.7 CBY21840.1 - 1.8e-06 27.9 25.8 0.00088 19.3 4.2 3.8 3 0 0 3 3 3 2 MSP1 EGF domain 1 hEGF PF12661.7 CBY21840.1 - 4.4e-06 27.1 33.5 0.00067 20.2 3.6 4.5 4 0 0 4 4 4 3 Human growth factor-like EGF cEGF PF12662.7 CBY21840.1 - 3.5e-05 23.6 13.6 0.0012 18.7 2.6 3.5 3 0 0 3 3 3 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY21840.1 - 0.0097 16.2 3.8 0.0097 16.2 3.8 4.8 3 1 1 4 4 4 2 Coagulation Factor Xa inhibitory site O-antigen_lig PF13425.6 CBY21840.1 - 0.086 11.6 0.2 0.18 10.6 0.0 1.6 2 0 0 2 2 2 0 O-antigen ligase like membrane protein SH2 PF00017.24 CBY21842.1 - 9.3e-14 51.3 0.3 1.6e-13 50.5 0.3 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CBY21842.1 - 9.2e-12 44.4 0.0 1e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CBY21842.1 - 2.4e-05 24.1 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CBY21842.1 - 3.2e-05 23.5 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain AAA_11 PF13086.6 CBY21844.1 - 4.4 7.0 11.1 0.47 10.2 3.7 2.1 2 0 0 2 2 2 0 AAA domain DUF1744 PF08490.12 CBY21845.1 - 2.5e-77 260.1 0.1 5.2e-77 259.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CBY21845.1 - 1.9e-71 241.0 0.4 6.8e-71 239.1 0.4 2.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CBY21845.1 - 2.2e-15 56.3 9.4 1.3e-14 53.9 3.9 3.5 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CBY21845.1 - 3.4e-06 26.9 1.2 8.3e-05 22.4 1.2 2.6 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CBY21845.1 - 4.6e-05 23.5 0.0 0.00021 21.3 0.0 2.2 1 0 0 1 1 1 1 RNase_H superfamily NAPRTase_C PF17956.1 CBY21845.1 - 0.15 12.5 0.6 1.2 9.6 0.0 2.9 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain ThiF PF00899.21 CBY21846.1 - 3.8e-59 200.0 0.0 5.8e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 CBY21846.1 - 8.6e-23 80.8 1.7 8.6e-23 80.8 1.7 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 CBY21846.1 - 1.9e-06 28.0 6.0 0.0025 17.8 0.1 3.0 1 1 3 4 4 4 3 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 CBY21846.1 - 0.00099 19.5 0.7 0.0035 17.8 0.0 2.2 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CBY21846.1 - 0.0022 18.1 0.1 0.0075 16.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase BTB PF00651.31 CBY21847.1 - 2.6e-26 92.0 0.1 4.7e-26 91.2 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY21847.1 - 2.3e-23 82.2 0.7 2.1e-22 79.2 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 CBY21847.1 - 1.6e-08 34.0 17.2 1.9e-06 27.3 0.0 6.3 6 1 0 6 6 6 1 Kelch motif Kelch_6 PF13964.6 CBY21847.1 - 1.9e-06 28.0 6.5 0.013 15.7 0.0 5.1 3 1 2 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CBY21847.1 - 5.4e-06 26.2 6.4 0.39 10.8 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CBY21847.1 - 0.00034 20.8 0.8 18 5.8 0.1 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY21847.1 - 0.0028 17.6 2.2 0.79 9.8 0.0 3.8 4 0 0 4 4 4 1 Kelch motif RRXRR PF14239.6 CBY21847.1 - 0.079 12.8 0.7 0.14 12.0 0.7 1.2 1 0 0 1 1 1 0 RRXRR protein Kelch_4 PF13418.6 CBY21848.1 - 0.00018 21.4 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY21848.1 - 0.00046 20.4 0.0 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.25 CBY21848.1 - 0.00052 19.5 0.0 0.0015 18.0 0.0 1.7 2 0 0 2 2 2 1 Kelch motif FAD_binding_3 PF01494.19 CBY21849.1 - 2.5e-17 63.2 0.0 7.8e-08 31.9 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CBY21849.1 - 0.046 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 CBY21849.1 - 0.092 11.8 0.1 0.39 9.7 0.0 2.0 3 0 0 3 3 3 0 Squalene epoxidase Ank_4 PF13637.6 CBY21850.1 - 8.3e-25 86.8 1.6 1.6e-09 38.1 0.0 4.3 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY21850.1 - 1.1e-22 80.4 1.9 3.5e-12 46.7 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY21850.1 - 5e-16 58.6 0.3 5.6e-05 23.3 0.0 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) FAD_binding_3 PF01494.19 CBY21850.1 - 1.3e-15 57.5 0.0 8.5e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Ank PF00023.30 CBY21850.1 - 3.2e-12 46.3 2.8 0.0091 16.4 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CBY21850.1 - 1.4e-10 40.4 1.3 1.4 9.7 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_2 PF12796.7 CBY21851.1 - 1.2e-32 112.3 0.9 6.5e-13 49.1 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY21851.1 - 7.6e-30 102.9 2.8 6.4e-10 39.4 0.0 5.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY21851.1 - 1.2e-21 76.5 0.3 5.1e-05 23.5 0.0 5.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY21851.1 - 7.3e-20 70.5 1.6 0.0013 19.1 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 CBY21851.1 - 1.1e-18 65.3 2.8 0.007 16.8 0.1 8.0 8 0 0 8 8 8 4 Ankyrin repeat Polysacc_deac_1 PF01522.21 CBY21851.1 - 0.16 11.8 0.0 0.38 10.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide deacetylase UcrQ PF02939.16 CBY21852.1 - 1.2e-08 34.7 1.1 1.7e-08 34.3 1.1 1.4 1 1 0 1 1 1 1 UcrQ family PPP4R2 PF09184.11 CBY21854.1 - 7.3 6.1 41.6 1.8e+03 -1.7 41.6 2.0 1 1 0 1 1 1 0 PPP4R2 DUF4922 PF16269.5 CBY21855.1 - 2.7e-05 24.0 0.0 0.0063 16.3 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4922) ATP_transf PF09830.9 CBY21855.1 - 0.034 14.3 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 ATP adenylyltransferase DcpS_C PF11969.8 CBY21855.1 - 0.083 13.4 3.1 11 6.6 0.1 2.6 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CBY21855.1 - 0.25 12.1 6.0 3.7 8.3 0.6 3.4 2 1 0 2 2 2 0 HIT domain DUF4400 PF14348.6 CBY21856.1 - 0.18 11.3 0.4 0.36 10.3 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4400) KIAA1430 PF13879.6 CBY21857.1 - 9.8e-10 39.1 11.2 9.8e-10 39.1 11.2 3.3 3 1 0 3 3 3 1 KIAA1430 homologue ATP-synt_G PF04718.15 CBY21858.1 - 2.2e-14 54.1 0.0 2.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit YoaP PF14268.6 CBY21858.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 YoaP-like CALM_bind PF16025.5 CBY21859.1 - 0.029 14.9 0.0 0.04 14.4 0.0 1.2 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding HdeA PF06411.11 CBY21859.1 - 0.17 12.1 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 HdeA/HdeB family Nup160 PF11715.8 CBY21862.1 - 2.3e-19 69.4 0.3 1.9e-13 50.0 0.5 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Titin_Ig-rpts PF06582.12 CBY21864.1 - 0.15 12.0 1.0 0.4 10.7 1.0 1.7 1 0 0 1 1 1 0 Titin repeat FMO-like PF00743.19 CBY21865.1 - 2e-27 95.8 0.2 2.5e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CBY21865.1 - 3e-15 56.3 0.0 3e-12 46.4 0.0 2.0 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CBY21865.1 - 8.4e-09 35.0 0.0 1.9e-07 30.6 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CBY21865.1 - 0.00064 19.0 0.0 0.0045 16.3 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase S-layer PF07752.11 CBY21866.1 - 0.035 13.1 0.1 3.9 6.4 0.0 2.3 2 0 0 2 2 2 0 S-layer protein Gln-synt_N PF03951.19 CBY21866.1 - 0.085 12.6 0.0 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain NTP_transferase PF00483.23 CBY21867.1 - 6.2e-22 78.4 0.0 8.9e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CBY21867.1 - 6.8e-10 38.3 3.7 5.4e-06 25.9 0.4 3.0 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBY21867.1 - 0.0003 20.5 0.7 0.0051 16.5 0.3 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 CBY21867.1 - 0.00058 20.2 0.0 0.00076 19.9 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 CBY21867.1 - 0.017 14.0 0.2 0.14 11.1 0.2 2.3 1 1 0 1 1 1 0 L-fucokinase DUF4954 PF16314.5 CBY21867.1 - 0.079 11.1 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Pkinase PF00069.25 CBY21868.1 - 9.9e-65 218.5 0.0 1.4e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21868.1 - 1.4e-32 113.0 0.0 1.9e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY21868.1 - 3.3e-08 33.2 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY21868.1 - 9e-07 28.0 0.0 2.4e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 CBY21868.1 - 0.00017 21.3 0.0 0.43 10.2 0.0 2.5 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CBY21868.1 - 0.005 15.9 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 CBY21868.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_5 PF14634.6 CBY21870.1 - 1e-06 28.6 16.4 1.7e-06 27.8 16.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY21870.1 - 1.4e-06 28.5 14.4 2.5e-06 27.7 14.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY21870.1 - 3.3e-06 26.9 10.7 6.3e-06 25.9 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY21870.1 - 0.00036 20.3 13.8 0.00066 19.5 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY21870.1 - 0.0007 19.6 7.3 0.0007 19.6 7.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY21870.1 - 0.0008 19.2 14.9 0.0016 18.2 14.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YabA PF06156.13 CBY21870.1 - 0.0034 18.0 2.2 0.0064 17.1 2.2 1.4 1 0 0 1 1 1 1 Initiation control protein YabA zf-RING_4 PF14570.6 CBY21870.1 - 0.0054 16.5 12.1 0.013 15.2 12.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY21870.1 - 0.047 13.6 11.3 0.12 12.2 11.3 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF5082 PF16888.5 CBY21870.1 - 0.052 13.8 0.6 0.087 13.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Med9 PF07544.13 CBY21870.1 - 0.068 13.3 2.2 0.16 12.1 2.2 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3287 PF11690.8 CBY21870.1 - 0.23 11.2 1.4 1.3 8.8 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) zf-RING_6 PF14835.6 CBY21870.1 - 0.5 10.3 8.3 0.26 11.2 5.4 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 CBY21870.1 - 1.4 8.8 11.6 3.2 7.6 11.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CBY21870.1 - 3 8.0 10.4 38 4.4 10.5 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CBY21870.1 - 4.1 7.8 12.8 11 6.4 12.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain FAM176 PF14851.6 CBY21872.1 - 0.08 12.6 2.2 0.11 12.2 2.2 1.2 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 CBY21872.1 - 0.2 11.7 5.3 0.26 11.3 5.3 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 CBY21872.1 - 0.9 8.8 7.1 1.2 8.4 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 CBY21872.1 - 1.3 8.1 5.6 1.7 7.7 5.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PBP1_TM PF14812.6 CBY21872.1 - 1.5 9.2 10.5 2.5 8.5 10.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 CBY21872.1 - 2 6.4 5.2 2.2 6.3 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi CH PF00307.31 CBY21875.1 - 6.1e-81 267.7 0.0 2.1e-24 85.8 0.2 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBY21875.1 - 4e-10 39.4 0.1 0.00013 21.7 0.1 3.9 4 0 0 4 4 4 3 CAMSAP CH domain p450 PF00067.22 CBY21876.1 - 2.5e-55 188.0 0.2 4.4e-55 187.3 0.2 1.3 1 0 0 1 1 1 1 Cytochrome P450 7tm_1 PF00001.21 CBY21877.1 - 0.051 12.9 0.2 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) PLDc PF00614.22 CBY21878.1 - 1.2e-17 63.3 0.3 8.1e-08 32.1 0.1 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CBY21878.1 - 1.2e-17 64.0 0.1 1e-07 31.9 0.1 3.3 2 1 0 2 2 2 2 PLD-like domain mTERF PF02536.14 CBY21878.1 - 1.1e-11 44.2 1.3 2.2e-11 43.3 1.3 1.5 1 0 0 1 1 1 1 mTERF DASH_Ask1 PF08655.10 CBY21878.1 - 0.088 12.7 0.1 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Ask1 Ribosomal_L31e PF01198.19 CBY21879.1 - 3.8e-38 129.6 2.6 3.8e-38 129.6 2.6 1.5 1 1 1 2 2 2 1 Ribosomal protein L31e F_actin_cap_B PF01115.17 CBY21880.1 - 1.2e-94 316.4 0.0 1.6e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Band_7 PF01145.25 CBY21880.1 - 0.051 13.6 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 SPFH domain / Band 7 family Tmemb_14 PF03647.13 CBY21881.1 - 1.7e-14 54.3 7.8 2e-14 54.1 7.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C PigN PF04987.14 CBY21881.1 - 0.016 14.1 4.3 0.021 13.7 4.3 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) YrhC PF14143.6 CBY21881.1 - 2.2 8.4 6.2 12 6.1 0.1 2.4 2 1 0 2 2 2 0 YrhC-like protein TctB PF07331.11 CBY21881.1 - 5.5 7.3 10.3 17 5.6 10.3 1.7 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family NAC PF01849.18 CBY21882.1 - 2.4e-17 62.6 2.0 1.3e-15 57.1 1.4 2.3 2 0 0 2 2 2 2 NAC domain GDA1_CD39 PF01150.17 CBY21883.1 - 5.3e-100 335.1 0.0 8.1e-100 334.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Adaptin_binding PF10199.9 CBY21884.1 - 8.6e-09 36.0 2.3 1.1e-07 32.5 1.9 2.4 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Ric8 PF10165.9 CBY21884.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Semialdhyde_dh PF01118.24 CBY21884.1 - 0.033 14.6 0.1 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Roc PF08477.13 CBY21885.1 - 6.5e-08 32.8 0.0 9.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY21885.1 - 0.00062 19.4 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CBY21885.1 - 0.0025 17.9 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CBY21885.1 - 0.0047 16.4 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Cas_DxTHG PF09455.10 CBY21886.1 - 0.0042 16.7 4.8 0.68 9.4 0.3 2.3 2 0 0 2 2 2 2 CRISPR-associated (Cas) DxTHG family Ank_4 PF13637.6 CBY21887.1 - 4.9e-31 106.7 0.5 1.7e-10 41.2 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY21887.1 - 1.5e-28 99.2 0.1 6.3e-14 52.3 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY21887.1 - 3.7e-27 94.0 0.1 3.8e-07 30.2 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY21887.1 - 6e-26 89.7 0.1 4e-08 33.4 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CBY21887.1 - 2.6e-22 76.5 0.1 6.3e-06 26.1 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat NABP PF07990.12 CBY21887.1 - 0.053 13.1 2.0 0.088 12.3 2.0 1.3 1 0 0 1 1 1 0 Nucleic acid binding protein NABP ARA70 PF12489.8 CBY21887.1 - 0.069 13.3 5.0 0.34 11.1 5.0 2.1 1 1 0 1 1 1 0 Nuclear coactivator DUF3672 PF12421.8 CBY21887.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III protein DUF4407 PF14362.6 CBY21887.1 - 0.16 11.3 3.8 0.28 10.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ER PF01133.17 CBY21890.1 - 1.7e-42 143.4 0.7 1.9e-42 143.3 0.7 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary PBP_N PF17093.5 CBY21891.1 - 0.048 13.9 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Calreticulin PF00262.18 CBY21892.1 - 5.9e-70 236.0 19.1 5.7e-51 173.5 9.0 2.8 2 1 1 3 3 3 2 Calreticulin family Pkinase PF00069.25 CBY21894.1 - 3.8e-18 65.8 0.0 2.3e-16 60.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21894.1 - 2.5e-13 49.9 0.0 4.1e-11 42.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase TPH PF13868.6 CBY21895.1 - 8.3e-62 208.7 137.0 9.8e-62 208.5 137.0 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain HJURP_mid PF12346.8 CBY21895.1 - 0.05 14.1 0.5 0.05 14.1 0.5 2.5 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat DUF1077 PF06417.12 CBY21896.1 - 1.8e-36 124.7 1.3 2.5e-36 124.2 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TPH PF13868.6 CBY21897.1 - 1.9e-10 39.8 27.3 1.9e-10 39.8 27.3 2.2 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain DUF3316 PF11777.8 CBY21897.1 - 1.2 9.2 7.3 0.84 9.7 5.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3316) PRE_C2HC PF07530.11 CBY21898.1 - 0.043 13.9 0.3 0.066 13.3 0.3 1.4 1 0 0 1 1 1 0 Associated with zinc fingers TPH PF13868.6 CBY21899.1 - 5.3e-22 77.8 34.7 6e-22 77.6 34.7 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Mt_ATP-synt_B PF05405.14 CBY21899.1 - 0.0055 16.3 5.6 0.0071 16.0 5.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1679 PF07914.11 CBY21899.1 - 0.17 10.7 2.6 0.21 10.4 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) PWWP PF00855.17 CBY21899.1 - 0.32 11.4 1.9 0.65 10.4 1.9 1.5 1 0 0 1 1 1 0 PWWP domain eIF3_subunit PF08597.10 CBY21899.1 - 0.34 10.8 12.2 0.43 10.4 12.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Asp-B-Hydro_N PF05279.11 CBY21899.1 - 1.9 8.5 12.1 2.1 8.3 12.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4337 PF14235.6 CBY21899.1 - 3.6 7.7 9.7 4.8 7.3 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sec62 PF03839.16 CBY21899.1 - 4 6.9 5.5 4.6 6.7 5.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 TSP_1 PF00090.19 CBY21900.1 - 0.0013 18.9 9.5 0.0013 18.9 9.5 3.2 3 0 0 3 3 3 1 Thrombospondin type 1 domain Ephrin_rec_like PF07699.13 CBY21900.1 - 0.11 12.2 16.4 0.088 12.6 8.9 3.4 1 1 1 2 2 2 0 Putative ephrin-receptor like Pkinase PF00069.25 CBY21902.1 - 8.1e-71 238.5 0.0 1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21902.1 - 4.9e-34 117.8 0.0 7.4e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY21902.1 - 2.9e-08 33.4 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY21902.1 - 0.02 13.8 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Thioredoxin_2 PF13098.6 CBY21903.1 - 0.016 15.7 0.1 0.033 14.7 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like domain IL15 PF02372.15 CBY21903.1 - 0.02 14.9 0.4 0.029 14.4 0.2 1.4 2 0 0 2 2 2 0 Interleukin 15 Tau95_N PF17682.1 CBY21903.1 - 0.052 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Tau95 Triple barrel domain DUF2847 PF11009.8 CBY21903.1 - 0.15 12.0 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Trefoil PF00088.18 CBY21904.1 - 2.8e-17 62.3 27.7 4.5e-13 48.9 8.0 2.6 2 0 0 2 2 2 2 Trefoil (P-type) domain Alpha-amylase PF00128.24 CBY21904.1 - 6.6e-10 39.1 0.0 2e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 CBY21904.1 - 3.4e-09 37.0 0.1 1.8e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain PAS_11 PF14598.6 CBY21905.1 - 3.6e-14 52.9 0.0 7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 CBY21905.1 - 2.3e-12 47.0 0.0 5.3e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 PAS fold PAS PF00989.25 CBY21905.1 - 0.00035 20.5 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CBY21905.1 - 0.0041 17.4 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 PAS domain Flavodoxin_5 PF12724.7 CBY21905.1 - 0.026 14.8 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Kelch_3 PF13415.6 CBY21906.1 - 0.071 13.4 0.1 4 7.8 0.1 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF4775 PF16001.5 CBY21907.1 - 0.11 11.9 0.5 0.13 11.7 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) zf-B_box PF00643.24 CBY21907.1 - 0.72 10.1 11.2 0.39 10.9 2.1 2.6 2 1 1 3 3 3 0 B-box zinc finger Syntaxin PF00804.25 CBY21909.1 - 2.5e-48 164.4 25.2 3.6e-48 163.9 25.2 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 CBY21909.1 - 3.5e-12 46.1 0.2 3.5e-12 46.1 0.2 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 CBY21909.1 - 1.5e-07 31.7 17.2 1.5e-07 31.7 17.2 2.7 1 1 1 2 2 2 1 Syntaxin-like protein Baculo_PEP_C PF04513.12 CBY21909.1 - 0.02 14.9 11.7 0.061 13.4 5.7 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.21 CBY21909.1 - 0.021 14.6 14.2 0.2 11.5 0.8 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spectrin PF00435.21 CBY21909.1 - 0.022 15.2 13.8 0.65 10.5 7.2 2.5 2 0 0 2 2 2 0 Spectrin repeat COG5 PF10392.9 CBY21909.1 - 0.051 13.7 11.0 1.6 8.9 6.1 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Tricorn_C1 PF14684.6 CBY21909.1 - 0.057 13.5 0.5 1.9 8.6 0.0 2.6 2 1 0 2 2 2 0 Tricorn protease C1 domain DUF4226 PF10774.9 CBY21909.1 - 0.18 12.1 8.0 0.13 12.5 4.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) DSBA PF01323.20 CBY21909.1 - 0.18 11.6 2.8 0.21 11.3 1.9 1.6 1 1 0 2 2 2 0 DSBA-like thioredoxin domain DUF948 PF06103.11 CBY21909.1 - 0.2 12.0 10.4 9.1 6.6 4.5 3.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.8 CBY21909.1 - 0.22 10.7 10.8 0.054 12.7 6.9 1.9 1 1 0 2 2 2 0 Invariant surface glycoprotein LOH1CR12 PF10158.9 CBY21909.1 - 0.61 10.1 13.5 3.1 7.8 5.6 2.7 2 1 0 2 2 2 0 Tumour suppressor protein PRKG1_interact PF15898.5 CBY21909.1 - 0.71 10.8 23.4 2.5 9.1 2.6 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 CBY21909.1 - 1.3 9.1 21.3 1.6 8.8 3.6 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 CBY21909.1 - 1.7 9.0 9.2 3.3 8.0 1.8 3.6 2 2 2 4 4 4 0 Proteins of 100 residues with WXG Fzo_mitofusin PF04799.13 CBY21909.1 - 2.2 7.8 15.6 1.5 8.3 8.0 2.9 2 1 1 3 3 3 0 fzo-like conserved region DUF3800 PF12686.7 CBY21909.1 - 2.6 8.7 7.1 18 6.0 7.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Laminin_II PF06009.12 CBY21909.1 - 3.2 7.8 17.7 0.98 9.4 8.4 3.0 2 2 1 3 3 3 0 Laminin Domain II Erp_C PF06780.11 CBY21909.1 - 4.1 7.4 13.2 2.1 8.3 0.6 3.2 2 1 1 3 3 3 0 Erp protein C-terminus DUF883 PF05957.13 CBY21909.1 - 5 7.8 10.8 8.6 7.0 5.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Allexi_40kDa PF05549.11 CBY21909.1 - 6.1 6.3 13.9 1.4 8.4 6.9 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein NPV_P10 PF05531.12 CBY21909.1 - 8.8 6.9 15.4 1 9.9 4.5 3.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Lipocalin_9 PF17186.4 CBY21912.1 - 3 8.1 8.4 0.46 10.8 2.5 2.9 2 2 0 2 2 2 0 Lipocalin-like domain GOLD_2 PF13897.6 CBY21913.1 - 7.1e-69 230.6 4.3 7.1e-69 230.6 4.3 2.7 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking Caldesmon PF02029.15 CBY21913.1 - 0.00054 18.9 19.0 0.00054 18.9 19.0 1.6 2 0 0 2 2 2 1 Caldesmon MAP7 PF05672.11 CBY21913.1 - 0.00085 19.0 41.4 0.00085 19.0 41.4 1.6 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family GramPos_pilinD1 PF16555.5 CBY21913.1 - 0.014 15.5 2.4 4 7.6 0.9 3.1 2 1 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain DDRGK PF09756.9 CBY21913.1 - 0.33 10.5 32.2 0.57 9.8 32.2 1.4 1 0 0 1 1 1 0 DDRGK domain U79_P34 PF03064.16 CBY21913.1 - 8.4 5.7 19.1 16 4.8 19.1 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ArAE_1 PF06081.11 CBY21914.1 - 0.0098 16.0 0.4 0.011 15.8 0.4 1.1 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 ACBP PF00887.19 CBY21915.1 - 0.0026 18.0 0.1 0.0026 18.0 0.1 1.8 2 1 0 2 2 2 1 Acyl CoA binding protein Sec62 PF03839.16 CBY21915.1 - 0.13 11.7 8.8 0.19 11.2 8.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.12 CBY21915.1 - 0.64 9.8 9.7 0.81 9.5 9.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CBY21915.1 - 4.3 6.0 5.5 4.6 5.9 5.5 1.1 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 CBY21915.1 - 6.5 5.1 8.2 8.3 4.7 8.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cation_efflux PF01545.21 CBY21916.1 - 8.7e-48 162.7 14.3 1.1e-47 162.4 14.3 1.1 1 0 0 1 1 1 1 Cation efflux family zf-HIT PF04438.16 CBY21917.1 - 8.6e-11 41.5 12.7 1.7e-10 40.6 12.7 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 CBY21917.1 - 0.0027 17.4 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-Mss51 PF13824.6 CBY21917.1 - 0.048 13.8 6.4 0.044 13.9 4.0 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Sigma70_r4_2 PF08281.12 CBY21917.1 - 0.057 13.1 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Sterile PF03015.19 CBY21917.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Male sterility protein PolC_DP2 PF03833.13 CBY21917.1 - 1.2 7.0 5.6 1.9 6.3 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 CBY21917.1 - 2.2 8.4 14.5 1.3 9.2 12.1 1.9 2 0 0 2 2 2 0 MYND finger EMP24_GP25L PF01105.24 CBY21918.1 - 1.5e-34 119.5 4.4 2.6e-34 118.8 4.4 1.4 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5362 PF17319.2 CBY21918.1 - 0.072 12.9 0.4 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5362) PBP1_TM PF14812.6 CBY21918.1 - 0.16 12.3 8.9 0.35 11.3 8.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PEHE PF15275.6 CBY21919.1 - 4.5e-12 46.7 0.9 4.5e-12 46.7 0.9 2.6 2 1 1 3 3 3 1 PEHE domain Angiomotin_C PF12240.8 CBY21919.1 - 0.00021 20.9 0.1 0.00021 20.9 0.1 2.5 3 0 0 3 3 3 1 Angiomotin C terminal Rootletin PF15035.6 CBY21919.1 - 0.0024 17.9 2.2 0.0027 17.8 0.3 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 CBY21919.1 - 0.003 17.8 0.3 0.003 17.8 0.3 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) CENP-Q PF13094.6 CBY21919.1 - 0.0051 17.0 0.3 0.0051 17.0 0.3 2.5 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.15 CBY21919.1 - 9.6 6.1 7.9 1.7 8.5 0.9 2.4 2 0 0 2 2 2 0 Septum formation initiator EF-hand_7 PF13499.6 CBY21920.1 - 0.11 13.0 7.5 0.15 12.6 1.8 2.9 2 1 1 3 3 3 0 EF-hand domain pair SNF2_N PF00176.23 CBY21921.1 - 1.7e-55 188.2 1.6 2.9e-55 187.4 1.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY21921.1 - 1.7e-20 73.4 0.0 9.3e-20 71.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY21921.1 - 0.001 19.1 0.4 0.0047 16.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBY21921.1 - 0.0012 18.6 0.2 0.0043 16.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 CBY21921.1 - 0.017 14.8 0.0 0.068 12.8 0.0 2.0 1 0 0 1 1 1 0 DEAD_2 ERCC3_RAD25_C PF16203.5 CBY21921.1 - 0.026 13.7 0.1 0.091 12.0 0.1 1.9 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CRAL_TRIO_2 PF13716.6 CBY21922.1 - 3.3e-34 118.0 0.4 6.4e-34 117.1 0.4 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 CBY21922.1 - 5.7e-26 91.2 0.0 1.1e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 CBY21922.1 - 7.3e-15 55.0 2.3 4.5e-14 52.5 1.3 2.4 2 1 0 2 2 2 1 CRAL/TRIO domain DUF2067 PF09840.9 CBY21922.1 - 0.11 12.1 0.1 7.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) YvbH_ext PF11724.8 CBY21922.1 - 0.29 11.5 1.6 0.57 10.5 0.3 2.2 2 1 0 2 2 2 0 YvbH-like oligomerisation region DUF3899 PF13038.6 CBY21923.1 - 0.08 13.4 0.3 3.4 8.2 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) KASH PF10541.9 CBY21923.1 - 0.2 11.9 1.7 0.24 11.7 0.3 1.9 2 0 0 2 2 2 0 Nuclear envelope localisation domain Pkinase PF00069.25 CBY21924.1 - 2.3e-09 37.0 0.0 3.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21924.1 - 0.16 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Scramblase PF03803.15 CBY21925.1 - 1.2e-80 270.0 0.2 1.4e-80 269.7 0.2 1.0 1 0 0 1 1 1 1 Scramblase ITI_HC_C PF06668.12 CBY21926.1 - 0.0046 16.6 0.0 0.012 15.3 0.0 1.7 1 1 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Apis_Csd PF11671.8 CBY21926.1 - 2.8 7.9 11.2 0.44 10.6 7.5 1.5 2 0 0 2 2 2 0 Complementary sex determiner protein O-FucT PF10250.9 CBY21927.1 - 7.2e-11 42.4 0.2 1.3e-10 41.5 0.2 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase baeRF_family5 PF18846.1 CBY21927.1 - 0.093 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 Metallophos PF00149.28 CBY21928.1 - 1.5e-13 51.7 0.7 2.7e-13 50.9 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBY21928.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DnaJ_C PF01556.18 CBY21929.1 - 2.7e-40 137.9 0.3 3.6e-40 137.5 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBY21929.1 - 5.9e-27 93.6 0.3 1.3e-26 92.5 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBY21929.1 - 9.2e-13 48.4 20.8 1.7e-12 47.5 20.8 1.5 1 0 0 1 1 1 1 DnaJ central domain E1-E2_ATPase PF00122.20 CBY21930.1 - 2.1e-54 183.8 3.3 2.3e-53 180.4 0.4 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBY21930.1 - 4.3e-39 134.1 6.8 4.3e-39 134.1 6.8 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CBY21930.1 - 4e-21 76.3 2.7 4.2e-20 72.9 2.7 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY21930.1 - 6.4e-21 74.2 0.3 1.5e-20 73.0 0.3 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBY21930.1 - 7.9e-17 60.7 0.2 3.8e-16 58.5 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBY21930.1 - 2.8e-07 30.6 3.3 1.2e-06 28.5 1.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY21930.1 - 4.7e-06 27.1 0.0 3.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase OB_NTP_bind PF07717.16 CBY21931.1 - 3.3e-19 69.0 0.0 8.8e-19 67.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CBY21931.1 - 7.2e-19 68.1 0.1 1.8e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY21931.1 - 5.3e-15 55.7 0.6 1.2e-14 54.5 0.2 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY21931.1 - 2.3e-06 27.5 0.6 2.3e-05 24.2 0.4 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY21931.1 - 0.0081 16.4 0.3 0.082 13.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CBY21931.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 CBY21931.1 - 0.048 12.7 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CBY21931.1 - 0.05 13.9 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY21931.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBY21931.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 CBY21932.1 - 4.5e-16 58.9 0.5 0.094 13.6 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY21932.1 - 1.9e-05 24.8 0.0 0.28 11.5 0.0 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain THEG PF14912.6 CBY21933.1 - 7.5e-07 29.5 2.3 6.6e-05 23.3 0.1 2.3 2 1 1 3 3 3 3 Testicular haploid expressed repeat Ribosomal_L28e PF01778.17 CBY21934.1 - 1.7e-33 115.8 0.1 1.7e-33 115.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CBY21934.1 - 2.2e-26 92.4 15.3 4.6e-26 91.3 15.3 1.6 1 1 0 1 1 1 1 Mak16 protein C-terminal region SURF2 PF05477.11 CBY21934.1 - 0.31 10.7 12.2 0.22 11.2 10.9 1.4 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Pkinase PF00069.25 CBY21935.1 - 4.9e-70 235.9 0.0 6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21935.1 - 3.6e-34 118.2 0.0 5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY21935.1 - 9.8e-07 28.3 0.5 1.6e-06 27.6 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY21935.1 - 9.9e-05 21.8 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY21935.1 - 0.00075 19.5 0.1 0.0052 16.7 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY21935.1 - 0.0047 15.9 0.0 0.0072 15.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBY21935.1 - 0.024 14.2 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 CBY21936.1 - 9.9e-13 48.0 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21936.1 - 3.4e-07 29.8 0.0 4.2e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MIX PF18529.1 CBY21936.1 - 0.059 13.1 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins Pkinase PF00069.25 CBY21937.1 - 7.3e-40 137.0 0.0 1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY21937.1 - 1.3e-14 54.1 0.1 2.1e-14 53.5 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY21937.1 - 0.0021 18.0 0.1 0.0035 17.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBY21937.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CBY21937.1 - 0.18 11.1 0.2 0.31 10.4 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ PF00595.24 CBY21938.1 - 1.6e-54 182.2 4.3 4.9e-18 65.3 0.5 3.5 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 CBY21938.1 - 7.5e-50 169.1 0.5 1.6e-49 168.0 0.1 1.9 2 0 0 2 2 2 1 Guanylate kinase PDZ_6 PF17820.1 CBY21938.1 - 1.6e-23 82.3 0.2 5.9e-08 32.4 0.0 3.8 3 0 0 3 3 3 3 PDZ domain L27_1 PF09058.10 CBY21938.1 - 5.8e-19 67.8 3.1 1.2e-18 66.8 0.4 2.3 2 0 0 2 2 2 1 L27_1 PDZ_2 PF13180.6 CBY21938.1 - 2.3e-18 66.3 0.4 5.7e-06 26.6 0.0 3.8 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.28 CBY21938.1 - 6.1e-09 35.4 0.0 2.6e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CBY21938.1 - 9e-08 31.7 0.0 3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 CBY21938.1 - 0.021 14.7 0.0 0.23 11.4 0.0 2.8 3 0 0 3 3 3 0 Variant SH3 domain Cadherin_C PF01049.17 CBY21939.1 - 3e-36 124.9 0.7 6.6e-36 123.8 0.7 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin PF00028.17 CBY21939.1 - 1e-29 102.8 1.9 1.9e-08 34.7 0.0 5.2 5 0 0 5 5 5 4 Cadherin domain Cadherin_3 PF16184.5 CBY21939.1 - 3e-06 27.2 1.5 0.1 12.6 0.0 4.6 4 0 0 4 4 4 2 Cadherin-like Big_9 PF17963.1 CBY21939.1 - 0.00037 21.2 3.8 0.0059 17.3 0.1 3.3 3 0 0 3 3 3 1 Bacterial Ig domain DUF4834 PF16118.5 CBY21939.1 - 0.036 15.0 0.1 1.2 10.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Glyco_hydro_12 PF01670.16 CBY21939.1 - 0.053 13.5 0.1 0.088 12.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 ASFV_J13L PF05568.11 CBY21939.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Cadherin_4 PF17803.1 CBY21939.1 - 0.16 12.6 8.2 0.42 11.3 0.1 3.9 4 0 0 4 4 4 0 Bacterial cadherin-like domain MMR1 PF08505.10 CBY21940.1 - 0.055 13.8 9.5 0.06 13.6 9.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 CBY21940.1 - 0.64 8.7 18.1 0.77 8.5 18.1 1.1 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 CBY21940.1 - 0.87 8.9 8.4 1.2 8.5 8.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Borrelia_P83 PF05262.11 CBY21940.1 - 1.4 7.3 32.0 1.7 7.0 32.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein GREB1 PF15782.5 CBY21940.1 - 1.9 5.5 11.7 2.3 5.2 11.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CBY21940.1 - 2.7 7.1 8.9 3.1 6.9 8.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PA26 PF04636.13 CBY21940.1 - 2.7 6.8 14.3 3.3 6.5 14.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Dsh_C PF12316.8 CBY21940.1 - 4.4 7.6 21.8 9.3 6.6 21.8 1.5 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal NPAT_C PF15712.5 CBY21940.1 - 5 5.6 18.2 5.9 5.4 18.2 1.1 1 0 0 1 1 1 0 NPAT C terminus GAGA_bind PF06217.12 CBY21940.1 - 5.2 7.3 12.5 7.1 6.8 12.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CBY21940.1 - 5.7 6.7 27.0 8.3 6.2 27.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.6 CBY21940.1 - 6.4 7.3 17.9 7.6 7.1 17.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4746 PF15928.5 CBY21940.1 - 6.5 6.1 22.3 9.6 5.5 22.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AIF-MLS PF14962.6 CBY21940.1 - 6.6 6.7 26.1 8.7 6.3 26.1 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Red1 PF07964.11 CBY21940.1 - 8 4.6 19.1 9.2 4.4 19.1 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Asp-B-Hydro_N PF05279.11 CBY21940.1 - 10 6.1 32.1 13 5.7 32.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Shisa PF13908.6 CBY21941.1 - 0.00017 21.9 0.4 0.00036 20.8 0.4 1.7 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator MLANA PF14991.6 CBY21941.1 - 0.028 14.7 0.1 0.046 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein melan-A PsaL PF02605.15 CBY21941.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI TMEM154 PF15102.6 CBY21941.1 - 0.27 11.1 4.3 0.21 11.5 2.3 1.8 1 1 0 1 1 1 0 TMEM154 protein family TMEM52 PF14979.6 CBY21941.1 - 0.37 10.7 6.6 1.1 9.1 6.6 1.9 1 1 0 1 1 1 0 Transmembrane 52 NYAP_C PF15452.6 CBY21941.1 - 0.4 10.5 7.6 1.9 8.2 7.5 2.0 1 1 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Nucleo_P87 PF07267.11 CBY21941.1 - 2.3 7.0 6.4 3 6.6 6.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LRR_8 PF13855.6 CBY21942.1 - 5e-49 163.9 53.4 7.7e-17 60.8 3.0 6.8 3 3 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 CBY21942.1 - 1.1e-23 82.9 37.1 4.8e-06 26.8 1.1 7.4 2 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY21942.1 - 2.1e-22 79.4 8.1 1.4e-10 41.3 2.6 2.7 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY21942.1 - 2.6e-16 59.6 22.9 7e-08 32.2 2.5 4.5 3 2 2 5 5 5 4 Leucine-rich repeat I-set PF07679.16 CBY21942.1 - 2e-15 56.6 0.0 3.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY21942.1 - 1.8e-11 44.5 0.0 3.9e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY21942.1 - 5.6e-09 36.1 0.0 1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 CBY21942.1 - 1.5e-08 34.0 34.1 0.56 11.0 0.1 11.1 11 0 0 11 11 11 3 Leucine Rich Repeat LRRNT PF01462.18 CBY21942.1 - 1.8e-08 33.8 9.7 0.00067 19.2 2.8 2.6 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain Ig_2 PF13895.6 CBY21942.1 - 0.00047 20.4 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.6 CBY21942.1 - 0.0018 18.2 20.5 1.6 9.0 0.2 8.3 8 0 0 8 8 8 2 Leucine Rich repeat LRRCT PF01463.24 CBY21942.1 - 0.0054 17.2 1.0 4.8 8.0 0.0 3.4 3 0 0 3 3 2 1 Leucine rich repeat C-terminal domain V-set PF07686.17 CBY21942.1 - 0.034 14.3 0.0 0.21 11.8 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY21942.1 - 0.055 13.0 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain DUF4588 PF15251.6 CBY21943.1 - 4.7e-16 59.3 7.5 1.2e-15 58.0 7.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Spectrin_like PF18373.1 CBY21943.1 - 0.1 12.7 0.6 2.4 8.3 0.3 2.8 2 1 1 3 3 3 0 Spectrin like domain CREPT PF16566.5 CBY21943.1 - 0.2 11.8 2.5 0.41 10.8 2.5 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Uds1 PF15456.6 CBY21943.1 - 0.3 11.2 4.6 1.1 9.4 4.6 2.0 1 1 0 1 1 1 0 Up-regulated During Septation SH3_9 PF14604.6 CBY21944.1 - 2.6e-06 27.2 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY21944.1 - 1.6e-05 24.5 0.2 3.4e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 SH3 domain DUF4064 PF13273.6 CBY21944.1 - 0.00012 22.3 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) RseC_MucC PF04246.12 CBY21944.1 - 0.0033 17.4 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC SH3_2 PF07653.17 CBY21944.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain DUF4834 PF16118.5 CBY21944.1 - 0.026 15.5 1.5 0.083 13.9 1.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) G0-G1_switch_2 PF15103.6 CBY21944.1 - 0.035 14.5 0.0 0.052 14.0 0.0 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF2681 PF10883.8 CBY21944.1 - 0.04 14.3 0.0 0.062 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) OAD_gamma PF04277.13 CBY21944.1 - 0.041 14.5 0.0 0.041 14.5 0.0 1.7 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Gram_pos_anchor PF00746.21 CBY21944.1 - 0.09 12.7 0.3 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif FAM176 PF14851.6 CBY21944.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF4748 PF15932.5 CBY21944.1 - 0.27 11.0 0.9 0.67 9.7 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4748) BBS2_Mid PF14783.6 CBY21945.1 - 3.5e-05 23.8 0.0 0.02 14.9 0.0 2.8 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Mtc PF03820.17 CBY21947.1 - 2.7e-107 358.4 0.0 3e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier NIF PF03031.18 CBY21948.1 - 2.7e-55 186.4 1.5 5.2e-55 185.5 1.5 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UDG PF03167.19 CBY21949.1 - 3.9e-15 56.2 0.0 6.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RA PF00788.23 CBY21950.1 - 2.8e-10 40.7 0.1 1.1e-09 38.8 0.0 2.1 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain WW PF00397.26 CBY21951.1 - 2.4e-10 40.3 3.7 5e-10 39.3 3.7 1.6 1 0 0 1 1 1 1 WW domain SRI PF08236.11 CBY21951.1 - 8.1e-06 25.9 0.7 0.00019 21.5 0.0 2.6 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Glyco_hyd_101C PF17451.2 CBY21951.1 - 0.0006 20.1 2.2 0.022 15.0 0.8 2.6 2 0 0 2 2 2 1 Glycosyl hydrolase 101 beta sandwich domain DUF3683 PF12447.8 CBY21951.1 - 0.31 11.2 0.0 0.31 11.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3683) SET PF00856.28 CBY21952.1 - 8.7e-20 71.8 0.1 3e-19 70.0 0.1 1.8 1 1 0 1 1 1 1 SET domain AWS PF17907.1 CBY21952.1 - 7.4e-11 41.9 10.8 7.4e-11 41.9 10.8 1.8 2 0 0 2 2 2 1 AWS domain PAN_1 PF00024.26 CBY21954.1 - 5.3e-08 32.7 5.1 0.0013 18.7 0.3 2.2 1 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 CBY21954.1 - 1.2e-05 25.2 12.9 0.0036 17.2 1.2 3.0 3 0 0 3 3 3 2 PAN domain Galactosyl_T PF01762.21 CBY21955.1 - 2.3e-12 47.2 0.0 8.6e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Galactosyltransferase zf-C2H2_2 PF12756.7 CBY21956.1 - 6.4e-23 81.0 7.7 7.5e-19 67.9 0.0 2.9 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY21956.1 - 5.7e-06 26.5 9.0 2.1e-05 24.7 3.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 CBY21956.1 - 0.18 10.3 7.0 0.27 9.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 CBY21956.1 - 0.4 11.6 9.3 0.18 12.8 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CBY21956.1 - 0.63 10.5 9.3 0.15 12.5 3.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2856 PF11043.8 CBY21957.1 - 0.0063 16.6 0.2 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2856) UPF0182 PF03699.13 CBY21958.1 - 0.63 8.1 4.5 0.9 7.6 4.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Sulfatase PF00884.23 CBY21959.1 - 6.8e-69 232.6 0.0 9.6e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CBY21959.1 - 1.3e-28 100.2 0.0 1.9e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase CAAD PF14159.6 CBY21959.1 - 0.028 14.3 0.2 0.053 13.4 0.2 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1394 PF07159.12 CBY21960.1 - 6.1e-111 370.5 7.5 7e-111 370.3 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) ADIP PF11559.8 CBY21960.1 - 0.14 12.2 4.9 0.94 9.6 0.9 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GCP_C_terminal PF04130.13 CBY21961.1 - 1e-11 44.9 1.1 1.2e-11 44.7 1.1 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 CBY21962.1 - 4.7e-300 996.6 10.0 5.5e-300 996.4 10.0 1.0 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 GCP_N_terminal PF17681.1 CBY21962.1 - 0.021 14.5 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal DUF2151 PF10221.9 CBY21962.1 - 0.1 11.2 2.4 0.16 10.6 2.4 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Rad21_Rec8_N PF04825.13 CBY21963.1 - 3.9e-36 123.6 0.3 7.6e-36 122.6 0.3 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CBY21963.1 - 3.1e-15 55.2 0.0 6.7e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DZF PF07528.14 CBY21964.1 - 2.1e-11 44.0 0.7 6.3e-11 42.4 0.1 2.1 2 1 0 2 2 2 1 DZF domain dsrm PF00035.26 CBY21964.1 - 0.00071 20.2 0.0 0.0017 19.0 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Alpha_E3_glycop PF01563.16 CBY21964.1 - 0.046 13.8 0.1 0.15 12.1 0.1 1.9 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Bromodomain PF00439.25 CBY21965.1 - 1.5e-36 124.3 8.2 1.1e-18 67.0 0.3 2.8 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 CBY21965.1 - 1.4e-25 89.2 0.3 3.2e-25 88.1 0.3 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 CBY21965.1 - 0.034 14.1 0.8 0.034 14.1 0.8 2.5 3 0 0 3 3 3 0 FlxA-like protein Get5_C PF18514.1 CBY21965.1 - 0.18 11.5 0.2 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Get5 C-terminal domain RRM_1 PF00076.22 CBY21966.1 - 2.3e-10 40.2 0.0 4.6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tmemb_9 PF05434.11 CBY21967.1 - 1.5e-20 73.6 2.0 1.5e-20 73.6 2.0 2.0 2 1 0 2 2 2 1 TMEM9 MCLC PF05934.11 CBY21967.1 - 0.075 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) RRM_1 PF00076.22 CBY21968.1 - 1e-11 44.5 5.7 3.8e-10 39.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBY21968.1 - 0.027 14.3 0.0 0.088 12.6 0.0 1.9 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain CwsA PF10814.8 CBY21968.1 - 0.18 12.0 5.3 2.1 8.5 4.7 2.7 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA FUSC PF04632.12 CBY21968.1 - 9.3 4.6 7.0 13 4.2 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GRAM PF02893.20 CBY21969.1 - 1.2e-06 28.4 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 GRAM domain BBL5 PF07289.11 CBY21969.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 CBY21969.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 PQ-loop PF04193.14 CBY21970.1 - 1.5e-20 72.7 7.4 5.3e-16 58.1 3.5 3.1 3 1 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 CBY21970.1 - 0.0006 20.7 8.3 0.038 14.8 6.7 2.3 1 1 1 2 2 2 2 ER lumen protein retaining receptor Ferlin_C PF16165.5 CBY21970.1 - 2 8.4 6.5 0.25 11.3 1.2 2.0 1 1 1 2 2 2 0 Ferlin C-terminus 4HBT_2 PF13279.6 CBY21971.1 - 3.5e-05 24.3 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 CBY21971.1 - 0.00062 19.1 0.0 0.00083 18.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase DRY_EERY PF09750.9 CBY21972.1 - 3.1e-32 111.7 3.4 3.1e-32 111.7 3.4 5.2 3 2 0 3 3 3 1 Alternative splicing regulator ATP-synt_E PF05680.12 CBY21973.1 - 1.1e-08 35.3 0.1 1.4e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase E chain DUF4500 PF14937.6 CBY21974.1 - 1.3e-29 102.1 0.1 1.5e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) zf-Tim10_DDP PF02953.15 CBY21975.1 - 8.5e-14 51.0 3.3 8.5e-14 51.0 3.3 1.8 2 0 0 2 2 2 1 Tim10/DDP family zinc finger CLP1_P PF16575.5 CBY21976.1 - 6.8e-68 228.2 0.0 1e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CBY21976.1 - 3.2e-29 101.0 0.0 5.4e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CBY21976.1 - 9.1e-27 93.8 0.0 1.3e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 PduV-EutP PF10662.9 CBY21976.1 - 5.4e-05 23.0 0.1 0.1 12.3 0.1 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CBY21976.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CBY21976.1 - 0.0087 16.1 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 CBY21976.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CBY21976.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Resolvase PF00239.21 CBY21976.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain FAM220 PF15487.6 CBY21977.1 - 0.54 9.8 8.7 0.75 9.4 8.7 1.3 1 0 0 1 1 1 0 FAM220 family FGE-sulfatase PF03781.16 CBY21978.1 - 5.7e-79 265.4 5.0 9.7e-79 264.6 5.0 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 HTH_39 PF14090.6 CBY21978.1 - 0.00034 20.3 0.1 0.3 10.8 0.0 3.3 2 1 0 3 3 3 2 Helix-turn-helix domain AhpC-TSA PF00578.21 CBY21978.1 - 0.22 11.4 4.9 9.7 6.1 0.0 4.9 3 2 1 5 5 5 0 AhpC/TSA family PPV_E2_C PF00511.17 CBY21978.1 - 1.1 9.5 2.8 50 4.2 0.1 3.2 3 0 0 3 3 3 0 E2 (early) protein, C terminal DUF883 PF05957.13 CBY21978.1 - 5.4 7.7 28.6 6.7 7.4 0.1 5.9 2 2 3 6 6 6 0 Bacterial protein of unknown function (DUF883) FAD_binding_6 PF00970.24 CBY21979.1 - 2.8e-33 114.2 0.0 4.7e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBY21979.1 - 3.9e-31 107.9 0.0 1e-30 106.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CBY21979.1 - 7.4e-06 26.2 0.0 6.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain LysE PF01810.18 CBY21979.1 - 0.18 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 LysE type translocator Ldh_1_N PF00056.23 CBY21980.1 - 2.4e-36 124.9 0.2 3.5e-36 124.4 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBY21980.1 - 3.6e-34 118.1 0.0 8.5e-34 116.9 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain PE-PPE PF08237.11 CBY21980.1 - 0.09 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 PE-PPE domain Glycos_transf_2 PF00535.26 CBY21981.1 - 4.2e-26 91.8 0.0 7.5e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CBY21981.1 - 2.3e-07 30.4 0.1 4.5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 CBY21981.1 - 0.051 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_transf_64 PF09258.10 CBY21981.1 - 0.26 10.5 3.6 0.76 9.0 1.4 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain DUF2052 PF09747.9 CBY21983.1 - 0.0007 19.8 0.0 0.00089 19.4 0.0 1.3 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) COX_ARM PF06481.14 CBY21983.1 - 0.18 11.7 0.4 4.8 7.2 0.0 2.6 2 1 0 2 2 2 0 COX Aromatic Rich Motif DUF2052 PF09747.9 CBY21985.1 - 8.4e-07 29.3 15.4 8.4e-07 29.3 15.4 1.8 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Glycos_transf_4 PF00953.21 CBY21986.1 - 3.8e-34 118.0 7.3 3.8e-34 118.0 7.3 1.8 3 0 0 3 3 3 1 Glycosyl transferase family 4 RabGAP-TBC PF00566.18 CBY21987.1 - 4.4e-46 157.2 0.0 9.7e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CBY21987.1 - 4.9e-18 65.1 1.4 2.5e-09 37.0 0.5 2.8 2 1 0 2 2 2 2 GRAM domain DUF2301 PF10063.9 CBY21987.1 - 0.047 14.1 0.0 0.097 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) FHA PF00498.26 CBY21988.1 - 1.7e-16 60.3 0.0 3.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBY21988.1 - 3.9e-05 23.9 0.0 0.0017 18.6 0.0 2.5 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LRR_4 PF12799.7 CBY21989.1 - 9.2e-11 41.8 7.6 6.4e-06 26.4 0.0 4.9 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY21989.1 - 2.3e-06 27.3 3.1 1.1e-05 25.1 0.3 2.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 CBY21989.1 - 0.0045 16.5 1.0 0.024 14.2 0.1 2.4 1 1 1 2 2 2 1 Leucine-rich repeat DUF966 PF06136.13 CBY21989.1 - 0.023 14.4 4.2 0.032 14.0 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FoP_duplication PF13865.6 CBY21989.1 - 0.09 13.3 0.1 0.09 13.3 0.1 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 LRR_6 PF13516.6 CBY21989.1 - 0.13 12.4 0.1 50 4.3 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CBY21989.1 - 0.62 10.8 5.2 83 4.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat PDZ PF00595.24 CBY21990.1 - 5.9e-18 65.0 0.4 2.7e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY21990.1 - 5.7e-17 61.3 0.1 6.5e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY21990.1 - 5.8e-09 36.2 0.0 3e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CBY21990.1 - 0.0032 17.4 0.0 0.42 10.6 0.0 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain TCP PF03634.13 CBY21993.1 - 0.013 16.0 2.0 0.018 15.6 2.0 1.1 1 0 0 1 1 1 0 TCP family transcription factor EamA PF00892.20 CBY21994.1 - 7.5e-05 22.9 16.5 0.0031 17.7 11.8 2.3 2 1 0 2 2 2 2 EamA-like transporter family VKG_Carbox PF05090.14 CBY21994.1 - 0.0062 15.4 0.3 0.0067 15.3 0.3 1.2 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase DUF3040 PF11239.8 CBY21994.1 - 0.06 13.6 6.4 1 9.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Phage_holin_3_6 PF07332.11 CBY21994.1 - 2 8.5 0.0 2 8.5 0.0 2.7 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF202 PF02656.15 CBY21994.1 - 8 7.0 7.9 13 6.4 3.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) NIDO PF06119.14 CBY21995.1 - 0.00092 20.1 0.1 0.0024 18.8 0.1 1.7 1 0 0 1 1 1 1 Nidogen-like PXA PF02194.15 CBY21996.1 - 1.3e-34 119.7 2.3 1.3e-34 119.7 2.3 2.6 2 0 0 2 2 2 1 PXA domain RGS PF00615.19 CBY21996.1 - 9.8e-17 61.3 2.5 9.8e-17 61.3 2.5 2.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain Nexin_C PF08628.12 CBY21996.1 - 7.7e-16 58.7 0.0 7.9e-15 55.4 0.0 2.8 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 CBY21996.1 - 3.2e-09 36.8 0.3 9.4e-09 35.3 0.3 1.8 1 0 0 1 1 1 1 PX domain HSP70 PF00012.20 CBY21997.1 - 5.1e-258 857.2 15.1 5.9e-258 857.0 15.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBY21997.1 - 7.2e-16 57.9 4.4 4.7e-15 55.2 2.3 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CBY21997.1 - 7.1e-06 25.9 0.0 1.8e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CBY21997.1 - 1.7e-05 25.2 3.4 0.0095 16.3 0.5 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Caskin-tail PF16632.5 CBY21997.1 - 0.1 13.0 2.8 0.38 11.2 2.8 2.0 1 0 0 1 1 1 0 C-terminal region of Caskin ELMO_CED12 PF04727.13 CBY21998.1 - 1.3e-30 106.8 0.2 3.4e-30 105.5 0.1 1.7 2 1 1 3 3 3 1 ELMO/CED-12 family TonB_2 PF13103.6 CBY21999.1 - 0.049 13.9 0.1 0.15 12.4 0.1 1.8 1 0 0 1 1 1 0 TonB C terminal LLC1 PF14945.6 CBY22000.1 - 8.3e-34 116.7 5.7 9.5e-34 116.5 5.7 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein FAM183 PF14886.6 CBY22000.1 - 0.091 13.5 5.0 0.25 12.1 5.0 1.7 1 1 0 1 1 1 0 FAM183A and FAM183B related Mit_KHE1 PF10173.9 CBY22000.1 - 0.1 12.7 2.2 0.11 12.5 2.2 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related PI3K_P85_iSH2 PF16454.5 CBY22000.1 - 0.15 11.7 5.4 0.19 11.3 5.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PAN_1 PF00024.26 CBY22001.1 - 3.6e-06 26.9 0.0 7.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 CBY22001.1 - 0.065 13.4 1.3 0.2 11.8 0.5 2.0 2 0 0 2 2 2 0 PAN-like domain DUF1664 PF07889.12 CBY22001.1 - 0.093 12.8 9.6 5 7.2 0.5 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) PAN_4 PF14295.6 CBY22001.1 - 0.12 12.3 0.8 0.3 11.0 0.8 1.6 1 0 0 1 1 1 0 PAN domain Prefoldin_2 PF01920.20 CBY22001.1 - 0.52 10.3 12.6 0.3 11.1 0.3 3.4 3 1 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.10 CBY22002.1 - 0.0018 18.5 9.0 0.017 15.3 4.1 2.6 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CBY22002.1 - 0.0075 16.3 7.0 0.1 12.6 0.6 2.6 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.8 CBY22002.1 - 0.02 15.3 6.0 0.98 9.8 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) KilA-N PF04383.13 CBY22002.1 - 0.026 14.4 0.2 0.026 14.4 0.2 2.0 2 1 0 2 2 2 0 KilA-N domain Apolipoprotein PF01442.18 CBY22002.1 - 0.031 14.2 3.6 0.18 11.7 3.6 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TBCC_N PF16752.5 CBY22002.1 - 0.038 14.4 4.8 0.094 13.2 1.0 2.8 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain HSBP1 PF06825.12 CBY22002.1 - 0.04 13.8 4.2 9.2 6.2 0.0 3.7 3 1 1 4 4 4 0 Heat shock factor binding protein 1 KIX PF02172.16 CBY22002.1 - 0.069 13.4 4.0 0.9 9.9 0.1 3.0 3 0 0 3 3 3 0 KIX domain MscS_porin PF12795.7 CBY22002.1 - 0.086 12.4 1.2 0.31 10.6 0.0 2.1 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF948 PF06103.11 CBY22002.1 - 0.1 12.9 6.5 0.2 11.9 1.2 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Cytochrom_C_2 PF01322.20 CBY22002.1 - 0.17 12.8 0.4 0.17 12.8 0.4 2.5 2 1 1 3 3 3 0 Cytochrome C' MtrB PF05440.12 CBY22002.1 - 0.18 12.3 0.3 0.85 10.1 0.2 2.2 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B TolA_bind_tri PF16331.5 CBY22002.1 - 0.2 11.8 2.2 2.9 8.0 0.2 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation BLOC1_2 PF10046.9 CBY22002.1 - 0.22 11.8 10.6 0.3 11.4 0.5 3.6 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LMBR1 PF04791.16 CBY22002.1 - 0.3 10.0 4.9 0.39 9.6 4.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4164 PF13747.6 CBY22002.1 - 0.43 10.9 6.2 2.4 8.5 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) Syntaxin_2 PF14523.6 CBY22002.1 - 0.49 10.8 10.7 5.7 7.4 3.9 3.0 2 1 1 3 3 3 0 Syntaxin-like protein NPV_P10 PF05531.12 CBY22002.1 - 0.57 10.7 10.0 4 8.0 0.0 4.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4709 PF15821.5 CBY22002.1 - 0.6 10.4 7.4 0.95 9.8 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) DUF745 PF05335.13 CBY22002.1 - 1.2 8.8 5.2 2.7 7.7 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF745) TMPIT PF07851.13 CBY22002.1 - 1.7 7.8 6.4 11 5.1 4.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein Snapin_Pallidin PF14712.6 CBY22002.1 - 5.2 7.6 7.5 12 6.4 0.7 3.5 2 1 1 4 4 4 0 Snapin/Pallidin DHR10 PF18595.1 CBY22002.1 - 8.9 6.4 10.2 10 6.2 0.6 3.5 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain Nop PF01798.18 CBY22003.1 - 1.5e-82 276.5 0.2 2.6e-82 275.8 0.2 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBY22003.1 - 1.4e-16 60.6 0.2 1.4e-16 60.6 0.2 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain LSM PF01423.22 CBY22004.1 - 1.1e-19 69.9 0.5 1.5e-19 69.4 0.5 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CBY22004.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Zona_pellucida PF00100.23 CBY22005.1 - 5.8e-16 59.1 2.6 7.8e-16 58.6 2.6 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain ROQ_II PF18386.1 CBY22006.1 - 0.036 13.9 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Roquin II domain Acyl-CoA_dh_M PF02770.19 CBY22009.1 - 2.1e-15 56.7 0.0 3.5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 CBY22009.1 - 5.3e-11 42.4 0.0 8.9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 CBY22009.1 - 8.6e-07 29.3 1.6 2.1e-06 28.0 0.5 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Chromo PF00385.24 CBY22010.1 - 7.7e-15 54.5 5.0 1.7e-14 53.5 5.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain tRNA-synt_1 PF00133.22 CBY22011.1 - 1.3e-229 763.4 0.2 1.7e-229 763.1 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CBY22011.1 - 1.2e-29 103.3 0.1 2.1e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CBY22011.1 - 3.4e-18 65.6 3.4 1.1e-05 24.4 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CBY22011.1 - 0.014 14.8 0.1 0.068 12.5 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain PID PF00640.23 CBY22013.1 - 3.4e-05 23.9 0.1 9.6e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Gly-zipper_OmpA PF13436.6 CBY22013.1 - 1.2 9.0 6.3 3 7.7 6.3 1.6 1 0 0 1 1 1 0 Glycine-zipper domain Ank_2 PF12796.7 CBY22015.1 - 2.2e-31 108.3 0.0 3.3e-14 53.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY22015.1 - 3.7e-27 94.3 0.8 8.2e-11 42.2 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 CBY22015.1 - 1.2e-25 90.2 14.4 1.2e-25 90.2 14.4 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 CBY22015.1 - 4.6e-25 87.3 1.4 9.4e-08 32.2 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY22015.1 - 8.9e-25 86.0 0.1 0.00011 22.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CBY22015.1 - 4.3e-21 72.7 0.2 0.00078 19.7 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat MARVEL PF01284.23 CBY22015.1 - 0.0038 17.2 2.6 0.099 12.7 0.0 2.2 1 1 1 2 2 2 1 Membrane-associating domain 7TM_GPCR_Srd PF10317.9 CBY22015.1 - 0.51 9.5 8.0 0.088 12.0 3.8 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd PRR20 PF15708.5 CBY22018.1 - 0.11 12.4 0.7 0.14 12.1 0.7 1.1 1 0 0 1 1 1 0 Proline-rich protein family 20 Vps23_core PF09454.10 CBY22019.1 - 0.26 11.3 1.1 1.5 8.8 0.3 2.6 2 0 0 2 2 2 0 Vps23 core domain Na_Ca_ex PF01699.24 CBY22020.1 - 8.9e-15 54.9 12.5 1.2e-14 54.5 12.5 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 CBY22021.1 - 1.6e-15 57.4 14.6 1.6e-15 57.4 14.6 1.9 2 0 0 2 2 2 1 Sodium/calcium exchanger protein cEGF PF12662.7 CBY22022.1 - 0.00027 20.8 21.2 0.24 11.4 1.6 4.6 3 0 0 3 3 3 3 Complement Clr-like EGF-like LYRIC PF15686.5 CBY22023.1 - 0.015 14.9 8.9 0.021 14.4 8.9 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family CAML PF14963.6 CBY22023.1 - 0.059 13.5 2.8 0.095 12.8 2.8 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand TEX15 PF15326.6 CBY22023.1 - 1.7 8.3 7.0 2.7 7.6 7.0 1.2 1 0 0 1 1 1 0 Testis expressed sequence 15 YL1 PF05764.13 CBY22023.1 - 2.2 8.3 13.9 3.4 7.7 13.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Macoilin PF09726.9 CBY22023.1 - 2.8 6.4 10.6 2.9 6.3 10.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF4820 PF16091.5 CBY22023.1 - 3.4 7.0 8.0 7 5.9 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PcfK PF14058.6 CBY22023.1 - 3.5 7.9 11.1 30 4.9 11.1 2.1 1 1 0 1 1 1 0 PcfK-like protein DUF5427 PF10310.9 CBY22023.1 - 4.2 6.2 11.6 6.2 5.7 11.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FSA_C PF10479.9 CBY22023.1 - 4.7 5.2 20.6 6.3 4.8 20.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CDO_I PF05995.12 CBY22024.1 - 9.2e-31 106.4 0.0 1.1e-29 102.9 0.0 2.0 1 1 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CBY22024.1 - 0.037 13.5 0.0 0.068 12.6 0.0 1.4 2 0 0 2 2 2 0 PCO_ADO bZIP_1 PF00170.21 CBY22025.1 - 4.8e-05 23.4 12.7 8.7e-05 22.6 12.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY22025.1 - 0.0026 17.8 11.1 0.0026 17.8 11.1 1.9 2 0 0 2 2 2 1 Basic region leucine zipper TMEM52 PF14979.6 CBY22025.1 - 0.11 12.5 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Transmembrane 52 DUF5045 PF16464.5 CBY22025.1 - 0.18 12.1 2.3 0.4 11.0 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) bZIP_Maf PF03131.17 CBY22025.1 - 0.34 11.4 12.1 0.07 13.7 7.2 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor TMCO5 PF14992.6 CBY22025.1 - 0.68 9.5 11.6 0.07 12.7 7.4 1.4 2 0 0 2 2 2 0 TMCO5 family Macoilin PF09726.9 CBY22025.1 - 4 5.9 12.2 1.3 7.5 9.0 1.7 2 0 0 2 2 2 0 Macoilin family Uso1_p115_C PF04871.13 CBY22025.1 - 4.3 7.7 11.9 0.33 11.3 5.8 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pkinase PF00069.25 CBY22026.1 - 5.1e-58 196.5 0.7 9.8e-58 195.6 0.7 1.5 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 CBY22026.1 - 2.8e-46 155.9 0.5 5.8e-12 46.0 0.1 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 CBY22026.1 - 4e-38 131.2 0.2 7.1e-38 130.4 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 CBY22026.1 - 6.9e-22 76.7 13.5 1e-08 34.7 0.4 5.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 CBY22026.1 - 6.1e-08 32.3 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY22026.1 - 0.00016 21.1 0.3 0.00032 20.1 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY22026.1 - 0.01 14.6 0.0 0.01 14.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CBY22026.1 - 0.2 11.5 2.0 9.8 6.0 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 CBY22028.1 - 1.6e-28 99.8 0.0 8.1e-28 97.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22028.1 - 9.5e-09 34.9 0.0 1.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 CBY22028.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SGL PF08450.12 CBY22029.1 - 0.026 14.1 0.0 1.3 8.5 0.0 2.4 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 CBY22029.1 - 0.036 14.1 1.2 1.5 9.0 0.0 3.7 4 0 0 4 4 4 0 NHL repeat GCIP PF13324.6 CBY22030.1 - 0.015 14.9 2.5 0.34 10.5 0.1 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF3446 PF11928.8 CBY22030.1 - 5.4 7.4 11.3 1.8 8.9 6.0 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Glycos_transf_2 PF00535.26 CBY22031.1 - 3e-24 85.7 0.0 5.1e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY22031.1 - 2.3e-17 63.5 0.7 3.3e-17 62.9 0.7 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CBY22031.1 - 4.1e-06 26.3 0.4 9.7e-06 25.2 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 CBY22031.1 - 0.0097 15.8 0.0 0.028 14.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 TssO PF17561.2 CBY22031.1 - 0.019 15.1 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO Glyco_tranf_2_2 PF10111.9 CBY22031.1 - 0.026 14.0 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 CBY22031.1 - 0.068 13.9 0.1 15 6.4 0.2 3.1 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Glycos_transf_2 PF00535.26 CBY22032.1 - 1e-27 97.0 0.0 1.7e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY22032.1 - 8e-16 58.5 1.7 2.2e-15 57.0 1.7 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 CBY22032.1 - 3.5e-06 27.1 0.0 1.4e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CBY22032.1 - 0.00036 20.1 0.1 0.0014 18.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY22032.1 - 0.0055 16.2 0.0 0.026 14.0 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 HIT PF01230.23 CBY22033.1 - 3.9e-31 107.7 0.0 4.8e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBY22033.1 - 4.1e-27 94.9 0.0 4.8e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 CBY22033.1 - 0.048 13.4 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain IPT PF01745.16 CBY22033.1 - 0.17 11.3 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase G5 PF07501.12 CBY22033.1 - 0.18 12.3 0.1 1.9 9.0 0.0 2.0 2 0 0 2 2 2 0 G5 domain PRKG1_interact PF15898.5 CBY22034.1 - 0.031 15.2 7.8 0.031 15.2 7.8 3.7 2 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.8 CBY22034.1 - 0.041 13.2 33.7 0.019 14.3 9.6 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) MtrB PF05440.12 CBY22034.1 - 0.072 13.5 0.9 0.57 10.6 0.1 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Filament PF00038.21 CBY22034.1 - 0.18 11.3 35.2 1.3 8.6 4.8 3.1 2 1 1 3 3 3 0 Intermediate filament protein APG6_N PF17675.1 CBY22034.1 - 0.31 11.6 46.8 5.1 7.6 20.6 3.8 1 1 2 3 3 3 0 Apg6 coiled-coil region HOOK PF05622.12 CBY22034.1 - 0.67 8.0 40.3 2.5 6.1 39.8 1.8 1 1 0 1 1 1 0 HOOK protein HrpB7 PF09486.10 CBY22034.1 - 1.1 9.6 15.1 1.6 9.1 4.2 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.8 CBY22034.1 - 3 7.9 49.9 0.057 13.4 12.2 5.3 2 2 4 6 6 6 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 CBY22034.1 - 3.4 8.4 33.9 0.23 12.1 1.7 4.7 1 1 3 4 4 4 0 Initiation control protein YabA UPF0242 PF06785.11 CBY22034.1 - 3.7 7.6 42.9 14 5.7 6.8 3.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Tropomyosin PF00261.20 CBY22034.1 - 4.5 6.6 41.0 0.6 9.4 5.9 3.1 1 1 2 3 3 3 0 Tropomyosin ATG16 PF08614.11 CBY22034.1 - 5.5 7.2 44.2 2.8 8.1 7.8 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 CBY22034.1 - 8.3 5.7 27.7 6.2e+03 -3.8 27.7 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 CBY22034.1 - 9 6.0 41.1 2.8 7.6 14.4 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) COBRA1 PF06209.13 CBY22035.1 - 1.6e-55 188.9 1.5 1.6e-55 188.9 1.5 1.6 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) DUF496 PF04363.12 CBY22035.1 - 0.0024 17.9 0.2 0.62 10.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF496) COBRA1 PF06209.13 CBY22036.1 - 0.0045 15.9 0.3 0.0057 15.6 0.3 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Vfa1 PF08432.10 CBY22036.1 - 1 9.7 14.9 1.6 9.0 14.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TMEM214 PF10151.9 CBY22036.1 - 7.9 4.8 12.9 8.8 4.6 12.9 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator CREPT PF16566.5 CBY22037.1 - 1.8e-39 135.2 3.0 3.8e-39 134.2 3.0 1.6 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 CBY22037.1 - 2.3e-16 60.3 0.4 8.3e-16 58.6 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. TPPII_N PF12583.8 CBY22037.1 - 0.041 14.5 1.8 0.063 13.9 1.0 1.7 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal DUF3209 PF11483.8 CBY22037.1 - 0.084 13.3 0.4 0.18 12.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Syntaxin_2 PF14523.6 CBY22037.1 - 0.23 11.8 3.0 0.19 12.1 0.7 2.1 2 0 0 2 2 2 0 Syntaxin-like protein BLOC1_2 PF10046.9 CBY22037.1 - 0.36 11.2 5.0 9.8 6.6 1.9 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CBY22037.1 - 0.5 9.2 5.4 2.3 7.0 2.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_1 PF00170.21 CBY22037.1 - 0.59 10.3 5.8 0.22 11.7 0.6 2.9 3 0 0 3 3 3 0 bZIP transcription factor Tropomyosin_1 PF12718.7 CBY22037.1 - 2.1 8.5 7.2 1.6 8.9 3.7 2.2 2 0 0 2 2 2 0 Tropomyosin like YabA PF06156.13 CBY22037.1 - 6.3 7.5 6.1 3.3 8.4 1.8 2.4 2 0 0 2 2 2 0 Initiation control protein YabA TRAPP PF04051.16 CBY22038.1 - 3.2e-29 101.5 0.0 3.7e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component T-box PF00907.22 CBY22040.1 - 1.1e-74 250.7 0.0 1.5e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 T-box Taxilin PF09728.9 CBY22041.1 - 0.0032 16.7 10.3 0.0032 16.7 10.3 2.1 1 1 1 2 2 2 1 Myosin-like coiled-coil protein UPF0449 PF15136.6 CBY22041.1 - 0.059 13.8 17.8 0.41 11.1 5.4 3.2 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 CALCOCO1 PF07888.11 CBY22041.1 - 0.076 11.9 29.3 0.59 8.9 29.3 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MtrG PF04210.13 CBY22041.1 - 0.12 12.2 0.3 0.12 12.2 0.3 2.9 2 2 3 5 5 5 0 Tetrahydromethanopterin S-methyltransferase, subunit G ZapB PF06005.12 CBY22041.1 - 0.16 12.4 31.7 0.58 10.6 8.2 3.3 1 1 1 2 2 2 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 CBY22041.1 - 0.21 11.8 33.0 0.91 9.8 13.9 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 CBY22041.1 - 0.22 10.8 26.3 0.34 10.2 7.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 CBY22041.1 - 0.24 11.9 6.9 1.8 9.1 0.2 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 CBY22041.1 - 0.37 9.6 34.4 0.55 9.1 18.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 CBY22041.1 - 0.37 11.4 20.6 7.1 7.3 1.8 3.2 1 1 1 2 2 2 0 Initiation control protein YabA OrfB_IS605 PF01385.19 CBY22041.1 - 0.46 10.7 5.6 0.25 11.6 1.6 2.1 2 0 0 2 2 2 0 Probable transposase MAAL_N PF05034.13 CBY22041.1 - 0.46 10.1 6.4 2.8 7.6 0.9 2.1 1 1 1 2 2 2 0 Methylaspartate ammonia-lyase N-terminus JIP_LZII PF16471.5 CBY22041.1 - 0.86 9.8 28.3 4.2 7.6 12.4 3.5 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II Macoilin PF09726.9 CBY22041.1 - 1.5 7.3 25.6 1.8 7.0 25.6 1.0 1 0 0 1 1 1 0 Macoilin family Sec34 PF04136.15 CBY22041.1 - 1.5 8.6 15.1 2.7 7.9 4.3 2.9 1 1 1 3 3 3 0 Sec34-like family Cluap1 PF10234.9 CBY22041.1 - 4.2 6.7 25.7 6.9 6.0 9.9 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 ESP PF16590.5 CBY22041.1 - 4.3 7.7 8.7 1.7 9.0 2.2 2.6 1 1 1 2 2 2 0 Exocrine gland-secreting peptide PIN_2 PF10130.9 CBY22041.1 - 5 7.4 12.5 0.7 10.1 4.9 2.6 1 1 2 3 3 3 0 PIN domain AAA_13 PF13166.6 CBY22041.1 - 6 5.4 22.6 6.9 5.2 22.6 1.0 1 0 0 1 1 1 0 AAA domain S36_mt PF10937.8 CBY22041.1 - 6.1 8.5 6.3 16 7.1 0.3 2.3 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial GAS PF13851.6 CBY22041.1 - 8.4 5.7 32.2 0.78 9.1 11.6 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 CBY22041.1 - 8.5 6.4 17.9 6.2 6.9 3.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DAO PF01266.24 CBY22043.1 - 0.00013 21.6 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 CBY22043.1 - 0.02 14.3 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase fn3 PF00041.21 CBY22046.1 - 7.6e-42 141.6 6.9 6.2e-12 45.7 0.0 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY22046.1 - 5.3e-06 26.9 9.6 1.1 9.9 0.1 5.8 5 2 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Laminin_G_3 PF13385.6 CBY22046.1 - 3.8e-05 23.9 0.0 7.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.15 CBY22046.1 - 7.2e-05 22.9 4.4 7.2e-05 22.9 4.4 2.3 2 0 0 2 2 2 1 Calcium-binding EGF domain Interfer-bind PF09294.10 CBY22046.1 - 0.00021 21.6 0.0 0.72 10.2 0.0 4.4 3 1 1 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III EGF PF00008.27 CBY22046.1 - 0.0012 19.1 1.8 0.0027 18.0 1.8 1.6 1 0 0 1 1 1 1 EGF-like domain DUF2369 PF10179.9 CBY22046.1 - 0.0081 16.5 0.1 5.4 7.5 0.0 3.5 3 1 0 3 3 3 1 Uncharacterised conserved protein (DUF2369) CBM_4_9 PF02018.17 CBY22046.1 - 0.042 14.1 5.0 0.069 13.4 0.2 3.4 3 1 1 4 4 4 0 Carbohydrate binding domain Plasmod_Pvs28 PF06247.11 CBY22046.1 - 0.06 13.7 6.5 0.15 12.4 6.5 1.7 1 0 0 1 1 1 0 Pvs28 EGF domain EB PF01683.18 CBY22046.1 - 0.074 13.4 2.4 0.23 11.8 2.4 1.7 1 0 0 1 1 1 0 EB module hEGF PF12661.7 CBY22046.1 - 0.089 13.5 1.0 0.22 12.2 1.0 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY22046.1 - 0.14 12.2 3.7 0.34 11.0 3.7 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 EGF_3 PF12947.7 CBY22046.1 - 0.23 11.7 3.6 0.63 10.3 3.6 1.7 1 0 0 1 1 1 0 EGF domain Zona_pellucida PF00100.23 CBY22047.1 - 2.2e-20 73.5 0.0 2.6e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain EF-hand_6 PF13405.6 CBY22048.1 - 2e-14 52.2 0.6 1.6e-06 27.6 0.2 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY22048.1 - 3.7e-14 51.1 0.4 5.4e-06 25.6 0.3 3.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY22048.1 - 5.9e-13 49.1 0.4 3.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY22048.1 - 7.8e-09 35.3 1.0 0.0034 17.2 0.0 3.1 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY22048.1 - 4.9e-08 32.1 6.6 1.5e-05 24.3 0.8 2.9 3 0 0 3 3 3 2 EF hand TRCF PF03461.15 CBY22048.1 - 0.033 14.6 0.1 0.054 13.9 0.1 1.3 1 0 0 1 1 1 0 TRCF domain EF-hand_9 PF14658.6 CBY22048.1 - 0.051 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY22048.1 - 0.062 13.6 0.2 0.2 12.0 0.1 1.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY22048.1 - 0.1 12.6 0.1 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand C2 PF00168.30 CBY22049.1 - 1.2e-50 170.1 0.6 2.1e-27 95.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CBY22049.1 - 0.0012 18.5 0.0 0.5 9.9 0.0 2.3 2 0 0 2 2 2 2 CEP76 C2 domain DOCK-C2 PF14429.6 CBY22049.1 - 0.0043 16.9 0.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF4489 PF14879.6 CBY22049.1 - 0.0064 16.6 0.6 0.018 15.1 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4489) PAG PF15347.6 CBY22049.1 - 0.0087 15.1 0.2 0.015 14.3 0.2 1.3 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched MAP17 PF15807.5 CBY22049.1 - 0.018 15.3 0.3 0.038 14.2 0.0 1.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Transglut_C PF00927.22 CBY22049.1 - 0.046 13.9 0.2 14 5.9 0.1 2.3 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain TMEM52 PF14979.6 CBY22049.1 - 0.049 13.5 0.3 0.1 12.5 0.3 1.5 1 0 0 1 1 1 0 Transmembrane 52 ILEI PF15711.5 CBY22051.1 - 6e-18 65.1 0.1 8.3e-18 64.7 0.1 1.1 1 0 0 1 1 1 1 Interleukin-like EMT inducer DIX PF00778.17 CBY22053.1 - 4.8e-07 29.5 0.1 1.7e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 DIX domain Axin_b-cat_bind PF08833.10 CBY22053.1 - 4.7e-06 26.6 0.2 0.00013 22.0 0.0 2.4 2 0 0 2 2 2 1 Axin beta-catenin binding domain DUF4367 PF14285.6 CBY22053.1 - 0.057 13.9 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) WD40 PF00400.32 CBY22054.1 - 7.2e-11 42.5 2.0 0.0042 17.9 0.1 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat HTH_Mga PF08280.11 CBY22054.1 - 0.3 11.1 2.2 0.55 10.3 0.1 2.6 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Kinesin PF00225.23 CBY22055.1 - 3.6e-108 361.4 0.5 3.6e-108 361.4 0.5 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY22055.1 - 3.8e-22 78.8 0.2 3.8e-22 78.8 0.2 3.6 3 1 1 4 4 4 1 Microtubule binding Lebercilin PF15619.6 CBY22055.1 - 0.0048 16.6 7.3 0.0048 16.6 7.3 4.4 3 1 1 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease Ribosomal_S2 PF00318.20 CBY22056.1 - 1.5e-25 89.7 0.2 2.7e-13 49.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CBY22056.1 - 1.1e-05 26.7 9.7 2.4e-05 25.6 9.7 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Lectin_leg-like PF03388.13 CBY22057.1 - 4.5e-63 212.7 0.0 6.9e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CBY22057.1 - 2.5e-08 34.2 0.7 3.8e-08 33.6 0.7 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CBY22057.1 - 0.012 15.2 0.0 0.094 12.2 0.0 2.1 2 1 0 2 2 2 0 Legume lectin domain RVT_3 PF13456.6 CBY22058.1 - 0.0071 16.2 0.8 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like zf-3CxxC_2 PF17180.4 CBY22060.1 - 1.8e-22 79.8 11.6 1.8e-22 79.8 11.6 4.2 4 1 0 4 4 4 2 Zinc-binding domain Ald_Xan_dh_C2 PF02738.18 CBY22061.1 - 1.4e-108 363.8 0.7 1.9e-108 363.3 0.7 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 CBY22061.1 - 4.8e-19 68.7 0.6 1e-18 67.7 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 CBY22061.1 - 8e-12 45.5 0.0 2.1e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 CBY22061.1 - 0.0044 17.0 0.1 0.015 15.3 0.1 2.0 1 0 0 1 1 1 1 [2Fe-2S] binding domain RabGAP-TBC PF00566.18 CBY22062.1 - 4.7e-37 127.7 0.3 9.2e-37 126.8 0.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TIM PF00121.18 CBY22063.1 - 5.1e-92 307.6 0.1 5.8e-92 307.5 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 CBY22063.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 CutC family WD40 PF00400.32 CBY22064.1 - 2.3e-05 25.1 4.9 0.33 11.9 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY22064.1 - 0.00016 21.9 0.5 3.2 8.1 0.2 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 CBY22064.1 - 0.0037 16.6 0.0 0.12 11.7 0.0 2.5 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region DUF1921 PF09081.10 CBY22064.1 - 0.0051 17.0 0.3 0.25 11.6 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1921) F-box-like PF12937.7 CBY22064.1 - 3.2 7.7 8.8 0.64 10.0 0.9 2.9 2 1 1 3 3 3 0 F-box-like F-box-like PF12937.7 CBY22065.1 - 3.2e-05 23.7 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY22065.1 - 0.0018 18.1 0.0 0.0053 16.6 0.0 1.7 2 0 0 2 2 2 1 F-box domain TBP PF00352.21 CBY22066.1 - 4.3e-57 190.0 0.9 1.7e-31 108.0 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CBY22066.1 - 1.9e-05 24.7 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) GST_C_4 PF14834.6 CBY22066.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-RING_2 PF13639.6 CBY22068.1 - 2.9e-12 46.7 5.6 4.7e-12 46.1 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBY22068.1 - 1.1e-09 37.9 3.8 2.3e-09 36.8 3.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.22 CBY22068.1 - 1.5e-09 37.7 0.1 1.1e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 PA domain zf-C3HC4_2 PF13923.6 CBY22068.1 - 2.7e-09 36.7 4.8 4.3e-09 36.1 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY22068.1 - 2.3e-07 30.6 5.7 3.7e-07 29.9 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY22068.1 - 1.6e-06 28.3 8.1 9.4e-06 25.8 8.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY22068.1 - 0.00022 21.1 4.1 0.00033 20.5 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY22068.1 - 0.0018 18.2 2.0 0.0048 16.9 2.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY22068.1 - 0.0092 15.8 3.5 0.017 15.0 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY22068.1 - 0.015 15.2 3.5 0.034 14.0 3.5 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CBY22068.1 - 0.033 14.2 2.0 0.074 13.1 2.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 CBY22068.1 - 0.068 13.2 2.3 0.17 11.9 2.3 1.7 1 1 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 CBY22068.1 - 0.14 12.0 4.4 0.25 11.2 4.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CBY22068.1 - 0.17 12.1 3.4 0.61 10.3 3.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 CBY22068.1 - 0.23 11.3 3.4 0.41 10.6 3.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 CBY22068.1 - 0.28 11.5 3.4 0.48 10.8 3.4 1.4 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 CBY22068.1 - 0.31 10.7 2.7 0.54 9.9 2.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 CBY22068.1 - 1.9 8.7 5.4 3.9 7.7 5.4 1.6 1 0 0 1 1 1 0 RING-variant domain PCRF PF03462.18 CBY22069.1 - 1.8e-29 103.0 0.7 1.8e-29 103.0 0.7 2.4 2 1 0 3 3 3 1 PCRF domain RF-1 PF00472.20 CBY22069.1 - 2.2e-14 53.3 2.0 2.7e-14 53.1 0.1 2.0 2 0 0 2 2 2 1 RF-1 domain DUF4312 PF14189.6 CBY22069.1 - 0.028 14.4 0.1 0.077 13.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) Peptidase_M41 PF01434.18 CBY22069.1 - 0.1 12.4 1.4 0.2 11.4 1.4 1.5 1 0 0 1 1 1 0 Peptidase family M41 Med3 PF11593.8 CBY22069.1 - 0.22 10.7 0.3 0.34 10.0 0.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cut12 PF11500.8 CBY22069.1 - 8 6.4 9.6 3 7.8 5.0 2.3 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Ribosomal_S6 PF01250.17 CBY22070.1 - 1.6e-07 31.5 0.4 0.018 15.3 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein S6 Glycoprot_B_PH2 PF17417.2 CBY22070.1 - 0.62 10.4 3.0 0.9 9.9 2.0 1.7 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain Cpn60_TCP1 PF00118.24 CBY22071.1 - 1.7e-150 501.9 2.6 2e-150 501.7 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phytoreo_P8 PF07124.11 CBY22071.1 - 0.13 11.2 0.3 1.4 7.8 0.0 2.3 3 0 0 3 3 3 0 Phytoreovirus outer capsid protein P8 DAGK_acc PF00609.19 CBY22072.1 - 5.2e-41 140.6 0.0 1.1e-40 139.5 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBY22072.1 - 6.9e-23 80.6 0.0 1.4e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CBY22072.1 - 1.1e-10 41.2 29.5 3e-06 27.0 14.7 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.17 CBY22072.1 - 0.00017 21.7 0.1 0.00043 20.3 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) C1_2 PF03107.16 CBY22072.1 - 0.0056 17.0 2.9 0.0056 17.0 2.9 2.9 2 1 0 2 2 2 1 C1 domain Glycos_transf_2 PF00535.26 CBY22073.1 - 2.7e-36 125.0 0.0 3.6e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBY22073.1 - 4.1e-14 53.0 0.0 5.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CBY22073.1 - 5.4e-08 32.6 0.0 7.2e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CBY22073.1 - 0.00088 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 CBY22073.1 - 0.2 12.2 0.0 0.47 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 adh_short PF00106.25 CBY22075.1 - 7e-10 38.7 0.0 2.7e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY22075.1 - 1.9e-07 30.9 0.0 3e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 CBY22075.1 - 0.078 12.4 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PAP_assoc PF03828.19 CBY22076.1 - 9.8e-18 64.1 0.0 3.1e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY22076.1 - 1.5e-05 25.2 0.0 3.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain TniQ PF06527.11 CBY22076.1 - 0.049 14.3 0.1 0.049 14.3 0.1 2.2 3 1 0 3 3 3 0 TniQ zf-C3HC4 PF00097.25 CBY22077.1 - 2.1e-05 24.3 7.1 4.2e-05 23.3 7.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY22077.1 - 0.0002 21.3 8.9 0.00037 20.4 8.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY22077.1 - 0.00079 19.2 11.2 0.0018 18.1 11.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY22077.1 - 0.0024 18.0 1.9 0.0024 18.0 1.9 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING BshC PF10079.9 CBY22077.1 - 0.0065 15.3 1.2 0.0082 14.9 1.2 1.0 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC zf-RING_2 PF13639.6 CBY22077.1 - 0.011 16.0 8.2 0.021 15.1 8.2 1.5 1 1 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 CBY22077.1 - 0.022 14.6 6.0 0.044 13.6 6.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY22077.1 - 0.022 14.6 8.4 0.049 13.5 8.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY22077.1 - 0.036 14.2 6.3 0.17 12.1 6.5 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 CBY22077.1 - 0.073 13.1 1.2 0.073 13.1 1.2 1.9 1 1 1 2 2 2 0 RING-type zinc-finger VPS11_C PF12451.8 CBY22077.1 - 0.08 13.2 0.9 0.15 12.3 0.9 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal CtIP_N PF10482.9 CBY22077.1 - 0.11 12.6 6.0 0.16 12.0 4.5 2.0 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain zf-RING_4 PF14570.6 CBY22077.1 - 0.14 12.0 9.7 0.13 12.0 7.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain YabA PF06156.13 CBY22077.1 - 0.19 12.4 8.4 3.5 8.3 0.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA FeS PF04060.13 CBY22077.1 - 0.58 9.9 8.8 6.1 6.6 8.8 2.3 1 1 0 1 1 1 0 Putative Fe-S cluster ADIP PF11559.8 CBY22077.1 - 0.81 9.8 8.0 3.2 7.8 5.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TolA_bind_tri PF16331.5 CBY22077.1 - 0.94 9.6 6.3 2.6 8.2 0.9 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Baculo_IE-1 PF05290.11 CBY22077.1 - 0.95 9.4 5.8 0.6 10.1 3.8 1.7 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DHR10 PF18595.1 CBY22077.1 - 4.8 7.3 11.5 1.3 9.1 0.8 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Csm1_N PF18504.1 CBY22077.1 - 6.2 7.2 9.2 32 5.0 3.1 2.9 2 1 0 3 3 3 0 Csm1 N-terminal domain Tudor-knot PF11717.8 CBY22078.1 - 4.2e-08 33.0 2.2 8.5e-08 32.0 2.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 CBY22078.1 - 0.0062 16.9 0.5 0.022 15.1 0.5 2.0 1 0 0 1 1 1 1 PWWP domain Agenet PF05641.12 CBY22078.1 - 0.018 15.5 0.5 0.047 14.2 0.5 1.8 1 0 0 1 1 1 0 Agenet domain FapA PF03961.13 CBY22078.1 - 0.95 8.0 3.8 0.32 9.5 0.2 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A CBF PF03914.17 CBY22079.1 - 5.6e-25 88.3 1.4 6.1e-25 88.2 0.4 1.5 2 0 0 2 2 2 1 CBF/Mak21 family Glyco_hydro_18 PF00704.28 CBY22080.1 - 7.6e-14 52.1 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 tRNA-synt_2b PF00587.25 CBY22081.1 - 2.8e-38 131.7 0.0 4.9e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CBY22081.1 - 8.2e-15 55.0 5.2 2.8e-13 50.0 1.2 3.3 2 1 1 3 3 3 2 Seryl-tRNA synthetase N-terminal domain CPBP PF02517.16 CBY22082.1 - 6.7e-13 48.8 7.7 6.7e-13 48.8 7.7 1.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease FPN1 PF06963.12 CBY22083.1 - 2.5e-77 260.3 13.9 3.1e-75 253.4 13.9 2.0 1 1 0 1 1 1 1 Ferroportin1 (FPN1) Peptidase_C2 PF00648.21 CBY22084.1 - 4.5e-49 167.1 0.0 5e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease SAP PF02037.27 CBY22085.1 - 0.13 12.1 1.0 0.31 10.8 0.2 2.0 2 0 0 2 2 2 0 SAP domain PAP1 PF08601.10 CBY22086.1 - 0.0082 15.9 0.6 0.01 15.6 0.6 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 SAS4 PF15460.6 CBY22086.1 - 0.097 12.8 1.7 0.15 12.2 0.5 1.8 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 PRD PF00874.20 CBY22086.1 - 0.16 12.3 0.7 0.53 10.6 0.3 1.9 1 1 1 2 2 2 0 PRD domain Kinesin PF00225.23 CBY22087.1 - 1.3e-89 300.4 0.5 1.3e-89 300.4 0.5 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY22087.1 - 6e-17 62.0 0.4 3.5e-16 59.5 0.3 2.2 2 0 0 2 2 2 1 Microtubule binding Myb_DNA-binding PF00249.31 CBY22088.1 - 1.5e-08 34.7 0.1 2.7e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain FYVE_2 PF02318.16 CBY22088.1 - 0.0011 19.2 1.0 0.0018 18.5 1.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger HBB PF06777.11 CBY22088.1 - 0.033 13.9 1.3 2.4 7.8 0.5 2.9 2 1 1 3 3 3 0 Helical and beta-bridge domain Myb_DNA-bind_6 PF13921.6 CBY22088.1 - 0.038 14.2 0.1 0.085 13.1 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2452 PF10504.9 CBY22088.1 - 0.077 12.5 0.3 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) FapA PF03961.13 CBY22088.1 - 0.094 11.3 2.7 0.12 11.0 2.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-RING_2 PF13639.6 CBY22088.1 - 6.4 7.2 9.4 3.2 8.2 7.3 1.6 2 0 0 2 2 2 0 Ring finger domain 4F5 PF04419.14 CBY22089.1 - 2.7e-08 34.5 18.0 3.7e-08 34.1 18.0 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 CBY22089.1 - 0.00013 22.3 0.6 0.0002 21.6 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY22089.1 - 0.0072 16.6 1.4 0.012 15.9 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY22089.1 - 0.019 15.3 1.0 0.022 15.1 1.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF4464 PF14713.6 CBY22090.1 - 2.9e-86 288.7 0.4 3.2e-86 288.5 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) DUF5624 PF18538.1 CBY22090.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Pro_isomerase PF00160.21 CBY22091.1 - 8.6e-50 169.1 1.0 7.5e-49 166.0 0.1 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 CBY22091.1 - 1.5e-05 24.5 2.1 1.5e-05 24.5 2.1 2.1 2 1 0 2 2 2 1 Rtf2 RING-finger MSC PF09402.10 CBY22095.1 - 0.077 12.4 2.2 0.092 12.2 2.2 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF445 PF04286.12 CBY22095.1 - 0.2 11.4 7.5 0.24 11.2 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CemA PF03040.14 CBY22095.1 - 0.39 10.6 5.6 2.5 8.0 0.9 2.0 1 1 1 2 2 2 0 CemA family FAM199X PF15814.5 CBY22095.1 - 0.62 9.1 8.9 0.067 12.3 1.4 2.0 2 0 0 2 2 2 0 Protein family FAM199X DUF4337 PF14235.6 CBY22095.1 - 4.4 7.4 10.8 9.7 6.3 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Tantalus PF15386.6 CBY22096.1 - 1e-14 54.3 0.6 1e-14 54.3 0.6 1.7 2 0 0 2 2 2 1 Drosophila Tantalus-like DUF3896 PF13035.6 CBY22096.1 - 0.77 10.0 6.3 0.11 12.7 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) TRAM_LAG1_CLN8 PF03798.16 CBY22097.1 - 2.6e-32 112.2 20.3 2.6e-32 112.2 20.3 1.6 2 0 0 2 2 2 1 TLC domain adh_short PF00106.25 CBY22098.1 - 1.3e-41 142.2 3.6 2.6e-41 141.2 3.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY22098.1 - 3e-34 118.6 0.3 5.1e-34 117.9 0.3 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY22098.1 - 1.5e-11 44.5 0.4 3e-11 43.6 0.4 1.4 1 0 0 1 1 1 1 KR domain DUF4313 PF14190.6 CBY22098.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) Cyclin_N PF00134.23 CBY22099.1 - 2.2e-29 101.8 0.0 4.9e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4200 PF13863.6 CBY22099.1 - 7.1 7.1 9.6 0.78 10.2 1.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DEAD PF00270.29 CBY22101.1 - 5.8e-44 149.9 0.0 3.1e-43 147.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY22101.1 - 3.3e-30 104.7 0.0 9.5e-30 103.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 CBY22101.1 - 0.0012 18.8 2.3 0.0025 17.8 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle CMS1 PF14617.6 CBY22101.1 - 0.0063 15.9 0.1 0.0063 15.9 0.1 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CBY22101.1 - 0.016 15.3 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ITAM PF02189.15 CBY22101.1 - 0.13 12.7 0.0 0.37 11.4 0.0 1.8 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif Eclosion PF04736.12 CBY22101.1 - 0.2 11.3 0.7 1.6 8.5 0.1 2.7 3 0 0 3 3 3 0 Eclosion hormone Fibrinogen_C PF00147.18 CBY22102.1 - 5.5e-42 144.0 8.7 1.6e-30 106.6 4.4 3.1 2 1 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain AP_endonuc_2 PF01261.24 CBY22102.1 - 0.007 15.8 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2475 PF10629.9 CBY22103.1 - 4.4e-24 84.5 6.9 6e-11 42.4 0.4 4.4 3 1 1 4 4 4 4 Protein of unknown function (DUF2475) SEA PF01390.20 CBY22104.1 - 0.0068 16.5 2.6 0.015 15.3 2.6 1.7 1 1 0 1 1 1 1 SEA domain SEA PF01390.20 CBY22105.1 - 0.0061 16.6 2.1 0.018 15.1 2.1 1.7 1 1 0 1 1 1 1 SEA domain CAS_CSE1 PF03378.15 CBY22105.1 - 0.05 12.1 1.2 0.06 11.8 1.2 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus SEA PF01390.20 CBY22106.1 - 0.11 12.6 1.4 0.2 11.8 1.4 1.6 1 1 0 1 1 1 0 SEA domain DUF3165 PF11364.8 CBY22107.1 - 0.06 13.7 0.2 0.1 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) Phospholip_A2_1 PF00068.19 CBY22108.1 - 0.00089 19.7 6.5 0.00089 19.7 6.5 1.8 2 1 0 2 2 2 1 Phospholipase A2 Sulfate_transp PF00916.20 CBY22109.1 - 7e-95 318.0 16.8 1.4e-94 317.0 16.8 1.4 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CBY22109.1 - 9.3e-08 31.7 0.2 2e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 STAS domain GDP_Man_Dehyd PF16363.5 CBY22112.1 - 8e-55 186.5 0.0 2.2e-54 185.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY22112.1 - 2.2e-49 168.1 0.0 2.8e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CBY22112.1 - 6.6e-08 32.0 0.0 0.0011 18.2 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 CBY22112.1 - 1e-07 31.3 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CBY22112.1 - 2.8e-06 26.7 0.0 5.6e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CBY22112.1 - 1.3e-05 24.5 0.2 0.0011 18.2 0.1 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CBY22112.1 - 0.061 13.2 0.0 0.47 10.3 0.0 2.3 3 0 0 3 3 3 0 KR domain adh_short PF00106.25 CBY22112.1 - 0.14 11.6 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase SpecificRecomb PF10136.9 CBY22113.1 - 0.012 14.0 0.2 0.014 13.7 0.2 1.0 1 0 0 1 1 1 0 Site-specific recombinase UPF0242 PF06785.11 CBY22113.1 - 0.17 11.9 3.8 0.24 11.5 3.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SidE PF12252.8 CBY22113.1 - 0.42 8.1 3.6 0.48 7.9 3.6 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein LEM PF03020.15 CBY22115.1 - 3.5e-25 87.3 0.2 3.2e-12 45.8 0.1 2.6 2 0 0 2 2 2 2 LEM domain MSC PF09402.10 CBY22115.1 - 3e-10 40.1 0.0 4.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RecO_N_2 PF13114.6 CBY22115.1 - 0.12 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 RecO N terminal Xpo1 PF08389.12 CBY22117.1 - 4.5e-18 65.7 6.3 2.6e-17 63.3 0.1 4.7 3 3 2 5 5 5 1 Exportin 1-like protein Importin_rep PF18773.1 CBY22117.1 - 3.9e-16 58.5 0.0 9.3e-16 57.3 0.0 1.7 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 CBY22117.1 - 1.7e-06 28.0 0.0 7.8e-06 25.8 0.0 2.3 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 CBY22117.1 - 0.00094 19.0 1.7 0.0064 16.4 0.3 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain EH_Signature PF15611.6 CBY22117.1 - 0.056 12.9 0.3 0.17 11.3 0.3 1.8 1 0 0 1 1 1 0 EH_Signature domain FAM193_C PF15914.5 CBY22118.1 - 3.2e-05 23.6 0.2 3.2e-05 23.6 0.2 2.8 3 0 0 3 3 3 1 FAM193 family C-terminal PNISR PF15996.5 CBY22119.1 - 7.7e-05 23.1 5.9 7.7e-05 23.1 5.9 3.8 2 1 2 4 4 4 2 Arginine/serine-rich protein PNISR K1377 PF15352.6 CBY22120.1 - 0.00014 20.4 0.6 0.00014 20.4 0.6 5.7 1 1 2 5 5 5 3 Susceptibility to monomelic amyotrophy BMC PF00936.19 CBY22120.1 - 0.029 14.4 0.1 0.08 12.9 0.1 1.7 1 0 0 1 1 1 0 BMC domain PH_10 PF15411.6 CBY22121.1 - 0.045 14.0 0.1 0.095 13.0 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 CBY22121.1 - 0.049 14.1 0.0 0.089 13.3 0.0 1.4 1 0 0 1 1 1 0 PH domain Hydrolase_4 PF12146.8 CBY22122.1 - 6.7e-41 140.1 0.0 7.9e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY22122.1 - 1.6e-11 44.3 0.1 3.7e-07 30.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY22122.1 - 1.6e-10 42.0 0.0 2e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CBY22122.1 - 0.00029 20.6 0.0 0.0051 16.6 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 CBY22122.1 - 0.0035 16.9 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CBY22122.1 - 0.0096 15.4 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 CBY22122.1 - 0.013 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_8 PF06259.12 CBY22122.1 - 0.11 12.1 0.1 0.21 11.2 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase PGAP1 PF07819.13 CBY22122.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 CBY22122.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Zona_pellucida PF00100.23 CBY22124.1 - 2.3e-14 53.8 5.8 2.7e-09 37.2 1.4 2.3 1 1 0 2 2 2 2 Zona pellucida-like domain DUF382 PF04037.13 CBY22125.1 - 6e-58 194.5 1.7 6e-58 194.5 1.7 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 CBY22125.1 - 1.2e-19 69.9 3.0 3.8e-19 68.3 3.0 1.9 1 0 0 1 1 1 1 PSP SAP PF02037.27 CBY22125.1 - 1.5e-12 47.0 4.7 5.6e-11 41.9 2.0 3.1 2 0 0 2 2 2 2 SAP domain DUF4332 PF14229.6 CBY22125.1 - 0.0039 17.4 0.1 0.016 15.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4332) SUFU PF05076.13 CBY22126.1 - 1.2e-32 113.3 0.0 1.6e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) SUFU_C PF12470.8 CBY22126.1 - 3.1e-11 43.7 2.0 3.7e-10 40.2 0.1 2.1 1 1 1 2 2 2 2 Suppressor of Fused Gli/Ci N terminal binding domain Cyto_heme_lyase PF01265.17 CBY22127.1 - 8.4e-55 186.4 8.0 6.7e-54 183.4 8.0 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase PAXNEB PF05625.11 CBY22128.1 - 2.1e-40 139.0 0.0 3.1e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein Piwi PF02171.17 CBY22129.1 - 2e-81 273.6 0.0 2.4e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Piwi domain THF_DHG_CYH PF00763.23 CBY22129.1 - 0.044 14.0 0.0 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain zf-C2H2 PF00096.26 CBY22130.1 - 3.9e-15 55.4 20.2 7.1e-05 23.1 3.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY22130.1 - 1e-09 38.3 21.1 1.2e-05 25.5 0.9 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY22130.1 - 5.4e-09 36.1 18.2 0.0016 19.1 2.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 CBY22130.1 - 0.0035 17.9 6.7 0.04 14.5 1.0 3.0 1 1 2 3 3 3 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CBY22130.1 - 0.0082 16.4 3.7 0.76 10.1 0.3 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY22130.1 - 0.11 12.9 5.4 5.6 7.5 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type HSP70 PF00012.20 CBY22131.1 - 4.7e-19 68.0 0.1 5.2e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 CBY22131.1 - 0.028 14.1 0.0 0.083 12.6 0.0 1.6 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain PX PF00787.24 CBY22132.1 - 0.00074 19.5 0.1 0.0021 18.0 0.0 1.9 2 0 0 2 2 2 1 PX domain SNX17_FERM_C PF18116.1 CBY22132.1 - 0.003 17.6 0.0 0.0083 16.2 0.0 1.8 1 1 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain GRASP55_65 PF04495.14 CBY22133.1 - 7.8e-68 227.1 0.0 4.7e-50 169.5 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 CBY22133.1 - 4.9e-06 26.3 0.0 0.021 14.7 0.0 2.7 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY22133.1 - 0.00065 20.0 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 2 PDZ domain NRBF2 PF08961.10 CBY22133.1 - 2.9 7.5 11.9 3.6 7.2 1.0 2.6 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ECSIT PF06239.11 CBY22134.1 - 3.9e-14 52.3 0.0 1e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C PF14784.6 CBY22134.1 - 5.3e-10 39.7 0.0 4.7e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein Vps16_N PF04841.13 CBY22135.1 - 2e-35 122.3 0.0 3.1e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 CBY22135.1 - 8e-29 100.7 4.6 3.9e-28 98.4 4.6 1.9 1 1 0 1 1 1 1 Vps16, C-terminal region PTEN_C2 PF10409.9 CBY22137.1 - 3.1e-21 75.5 0.1 4.6e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 CBY22137.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBY22137.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY22137.1 - 0.063 13.2 0.1 0.099 12.6 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family EMP70 PF02990.16 CBY22138.1 - 3.1e-152 507.9 16.9 3.7e-152 507.6 16.9 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Thiolase_N PF00108.23 CBY22139.1 - 7.3e-69 232.0 2.0 1.9e-67 227.4 2.5 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY22139.1 - 8.8e-40 135.2 0.0 2.4e-39 133.8 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY22139.1 - 6.6e-05 22.6 1.1 0.00017 21.3 0.3 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 CBY22139.1 - 0.008 14.9 0.3 0.017 13.9 0.3 1.5 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 CBY22139.1 - 0.064 13.3 1.6 1.2 9.2 0.0 3.6 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain wnt PF00110.19 CBY22142.1 - 8e-72 242.4 28.5 9.7e-72 242.2 28.5 1.1 1 0 0 1 1 1 1 wnt family dsrm PF00035.26 CBY22143.1 - 7.8e-12 45.7 0.2 2.3e-06 28.2 0.0 4.1 4 0 0 4 4 4 2 Double-stranded RNA binding motif Zot PF05707.12 CBY22143.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) TAL_FSA PF00923.19 CBY22144.1 - 2.3e-91 306.1 0.0 2.6e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PCI PF01399.27 CBY22145.1 - 7.4e-06 26.4 0.0 1.1e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 CBY22145.1 - 0.0084 15.7 1.8 0.015 14.9 1.8 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Sigma70_r4_2 PF08281.12 CBY22145.1 - 0.0099 15.5 0.1 0.061 13.0 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 DUF507 PF04368.13 CBY22145.1 - 0.01 15.8 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Sigma70_r4 PF04545.16 CBY22145.1 - 0.021 14.3 0.2 0.088 12.4 0.0 2.1 3 0 0 3 3 3 0 Sigma-70, region 4 TFIIE_beta PF02186.15 CBY22145.1 - 0.03 14.6 0.0 0.055 13.8 0.0 1.6 1 1 0 1 1 1 0 TFIIE beta subunit core domain HTH_AsnC-type PF13404.6 CBY22145.1 - 0.035 13.9 0.0 2.6 7.9 0.0 2.3 1 1 1 2 2 2 0 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 CBY22145.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.6 1 1 1 2 2 2 0 IclR helix-turn-helix domain UPF0122 PF04297.14 CBY22145.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.8 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like MPP6 PF10175.9 CBY22147.1 - 5.9e-12 46.2 5.8 5.9e-12 46.2 5.8 1.8 1 1 1 2 2 2 1 M-phase phosphoprotein 6 ICMT PF04140.14 CBY22148.1 - 3.7e-21 75.4 0.0 4.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CBY22148.1 - 4e-07 30.4 0.0 4.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CBY22148.1 - 4.3e-05 22.4 0.4 5.4e-05 22.1 0.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CBY22148.1 - 0.0013 18.3 0.1 0.0015 18.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) QH-AmDH_gamma PF08992.11 CBY22148.1 - 0.071 13.1 0.1 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Cyclin_N PF00134.23 CBY22149.1 - 1.8e-09 37.4 1.4 6.9e-08 32.3 0.2 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 CBY22149.1 - 0.0033 17.4 0.0 0.011 15.7 0.0 2.0 2 1 0 2 2 2 1 Transcription factor TFIIB repeat PHM7_ext PF12621.8 CBY22150.1 - 0.1 12.8 0.7 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Extracellular tail, of 10TM putative phosphate transporter IBR PF01485.21 CBY22151.1 - 6.7e-16 58.3 47.0 6.4e-11 42.3 3.7 4.0 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 CBY22151.1 - 0.001 18.9 5.3 0.001 18.9 5.3 4.6 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY22151.1 - 0.0071 16.2 2.6 0.0071 16.2 2.6 4.3 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 DNA_pol_phi PF04931.13 CBY22152.1 - 0.87 7.6 6.3 0.98 7.4 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CBY22152.1 - 0.88 7.8 3.7 1 7.6 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Lipase_GDSL_2 PF13472.6 CBY22153.1 - 5.4e-05 23.7 0.0 9.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FliJ PF02050.16 CBY22153.1 - 0.16 12.2 3.8 0.37 11.0 3.8 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4147 PF13660.6 CBY22155.1 - 5.7e-39 134.0 0.0 6.8e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 CBY22156.1 - 3.2e-29 101.3 0.1 4.6e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 MOFRL family Pro_isomerase PF00160.21 CBY22157.1 - 4.2e-31 108.3 0.1 6.6e-31 107.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CBY22157.1 - 2.3e-16 59.4 0.1 5e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY22157.1 - 0.0081 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 CBY22157.1 - 3.6 6.3 15.6 4.6 6.0 15.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ANAPC15 PF15243.6 CBY22157.1 - 7.2 7.1 7.8 22 5.6 0.5 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 Nudc_N PF14050.6 CBY22158.1 - 2e-18 66.1 0.2 3.9e-18 65.2 0.2 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 CBY22158.1 - 9.7e-16 58.6 2.7 1.7e-15 57.8 2.7 1.4 1 0 0 1 1 1 1 CS domain Anoctamin PF04547.12 CBY22159.1 - 4.4e-102 342.2 14.7 5.8e-100 335.2 14.7 2.1 1 1 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CBY22159.1 - 6.9e-26 91.4 0.6 1.9e-25 89.9 0.6 1.8 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2362 PF10154.9 CBY22161.1 - 0.0083 15.1 0.3 0.0095 14.9 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DUF3040 PF11239.8 CBY22161.1 - 0.21 11.9 0.1 0.3 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF1299 PF06975.11 CBY22163.1 - 8 6.6 9.6 2.7 8.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1299) SAM_2 PF07647.17 CBY22165.1 - 0.00052 20.1 0.1 0.00087 19.4 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY22165.1 - 0.0014 19.0 0.1 0.002 18.5 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NUFIP1 PF10453.9 CBY22165.1 - 0.05 13.5 0.1 0.066 13.1 0.1 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) EF-hand_6 PF13405.6 CBY22166.1 - 2.8e-08 33.0 3.7 0.00089 19.0 0.1 3.1 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY22166.1 - 9.6e-08 31.1 2.9 0.006 16.0 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CBY22166.1 - 1.2e-06 28.9 4.5 0.014 15.8 1.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY22166.1 - 1.4e-05 24.4 5.5 0.0051 16.2 0.2 3.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CBY22166.1 - 0.00023 20.9 4.2 0.071 13.0 1.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair RBD-FIP PF09457.10 CBY22168.1 - 0.0012 18.7 0.7 0.0012 18.7 0.7 1.8 2 0 0 2 2 2 1 FIP domain ZapB PF06005.12 CBY22168.1 - 0.0048 17.3 3.7 0.02 15.3 3.7 1.9 1 1 0 1 1 1 1 Cell division protein ZapB Rx_N PF18052.1 CBY22168.1 - 0.0063 16.8 0.6 0.41 11.0 0.1 2.1 1 1 1 2 2 2 1 Rx N-terminal domain Cnn_1N PF07989.11 CBY22168.1 - 0.013 15.7 2.7 0.073 13.2 0.5 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 CBY22168.1 - 0.016 15.6 0.8 5.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4085 PF13315.6 CBY22168.1 - 0.025 14.2 1.9 0.03 13.9 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUF5082 PF16888.5 CBY22168.1 - 0.028 14.7 1.7 0.99 9.7 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF842 PF05811.13 CBY22168.1 - 0.14 11.9 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Pox_A_type_inc PF04508.12 CBY22168.1 - 0.27 11.1 0.5 0.27 11.1 0.5 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF5320 PF17253.2 CBY22168.1 - 1.1 10.4 2.1 29 5.8 0.2 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Spc7 PF08317.11 CBY22169.1 - 0.0041 16.1 22.9 0.006 15.5 22.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein SHE3 PF17078.5 CBY22169.1 - 0.0082 15.9 19.7 0.011 15.4 19.7 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF2316 PF10078.9 CBY22169.1 - 0.0094 16.2 5.5 0.016 15.5 5.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) YlqD PF11068.8 CBY22169.1 - 0.04 14.3 14.4 0.033 14.5 13.3 1.4 1 1 0 1 1 1 0 YlqD protein TarH PF02203.15 CBY22169.1 - 0.046 13.6 4.5 0.05 13.5 4.0 1.4 1 1 0 1 1 1 0 Tar ligand binding domain homologue TMCO5 PF14992.6 CBY22169.1 - 0.055 13.0 21.4 0.07 12.7 21.4 1.1 1 0 0 1 1 1 0 TMCO5 family THP2 PF09432.10 CBY22169.1 - 0.23 11.5 11.7 2.6 8.1 6.3 2.3 1 1 1 2 2 2 0 Tho complex subunit THP2 FliJ PF02050.16 CBY22169.1 - 0.26 11.5 19.7 0.17 12.1 8.6 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4200 PF13863.6 CBY22169.1 - 0.33 11.4 28.5 1 9.8 8.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.9 CBY22169.1 - 0.37 11.1 17.4 0.17 12.2 12.5 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 CBY22169.1 - 0.53 10.8 31.8 0.33 11.5 20.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Atg14 PF10186.9 CBY22169.1 - 0.81 8.7 20.2 1 8.4 20.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 CBY22169.1 - 1.5 8.9 27.8 0.43 10.6 9.1 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CBY22169.1 - 1.6 8.7 7.2 1.7 8.7 5.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3391 PF11871.8 CBY22169.1 - 2.8 8.5 9.3 0.67 10.5 5.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) FliD_N PF02465.18 CBY22169.1 - 3.2 8.5 12.4 0.66 10.7 6.8 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Prefoldin_2 PF01920.20 CBY22169.1 - 3.7 7.5 24.3 0.78 9.7 10.6 2.9 1 1 2 3 3 3 0 Prefoldin subunit CorA PF01544.18 CBY22169.1 - 3.9 6.7 11.3 4.6 6.5 11.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Peptidase_S46 PF10459.9 CBY22169.1 - 4.1 5.9 10.6 4.8 5.7 10.6 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF501 PF04417.12 CBY22169.1 - 5.7 6.8 8.4 1.5 8.6 4.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF501) TMPIT PF07851.13 CBY22169.1 - 5.7 6.1 16.0 2.1 7.5 13.2 1.6 1 1 1 2 2 2 0 TMPIT-like protein DHR10 PF18595.1 CBY22169.1 - 6.6 6.8 27.3 17 5.5 19.3 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Syntaxin-6_N PF09177.11 CBY22169.1 - 7.6 7.2 18.0 17 6.1 0.4 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 CBY22169.1 - 7.6 6.0 15.7 8.9 5.8 15.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CBY22169.1 - 7.7 5.8 14.7 15 4.8 14.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 CBY22169.1 - 10 4.9 13.1 12 4.6 13.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein RXLR_WY PF18634.1 CBY22170.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain WW PF00397.26 CBY22172.1 - 2.6e-06 27.4 4.1 5.2e-06 26.4 4.1 1.5 1 0 0 1 1 1 1 WW domain CDC45 PF02724.14 CBY22172.1 - 8.2 4.6 7.5 11 4.2 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Gal-3-0_sulfotr PF06990.11 CBY22173.1 - 1.1e-75 255.0 0.0 2.4e-75 253.9 0.0 1.4 1 1 1 2 2 2 1 Galactose-3-O-sulfotransferase Mucin PF01456.17 CBY22173.1 - 0.018 15.1 13.1 0.034 14.1 13.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein GTP-bdg_N PF13167.6 CBY22173.1 - 0.12 13.1 0.2 0.31 11.7 0.1 1.8 1 1 0 1 1 1 0 GTP-binding GTPase N-terminal Abi_HHR PF07815.14 CBY22174.1 - 7.2e-24 83.8 0.1 1.5e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.28 CBY22174.1 - 1.7e-15 56.4 0.3 4.3e-15 55.0 0.3 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY22174.1 - 9.2e-14 51.0 2.4 2.4e-13 49.7 0.9 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CBY22174.1 - 7.9e-12 44.7 0.1 1.8e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Asp_protease PF09668.10 CBY22176.1 - 1e-58 196.5 0.4 1.5e-58 196.0 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY22176.1 - 3.3e-21 75.6 0.0 7.8e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CBY22176.1 - 1.1e-08 35.6 0.0 2.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CBY22176.1 - 0.00021 21.1 0.0 0.00058 19.6 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.20 CBY22176.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 CBY22176.1 - 0.024 14.5 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain RPA_interact_M PF14767.6 CBY22176.1 - 8.4 7.0 8.3 2.1 9.0 2.8 2.8 3 1 0 3 3 3 0 Replication protein A interacting middle PAM2 PF07145.15 CBY22177.1 - 3.2e-06 26.4 0.1 4.8e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Cytochrom_B561 PF03188.16 CBY22178.1 - 1.7e-27 96.3 9.6 1.7e-27 96.3 9.6 2.5 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Sdh_cyt PF01127.22 CBY22178.1 - 0.97 9.5 14.0 0.54 10.3 0.5 2.8 1 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PepSY_TM PF03929.16 CBY22178.1 - 3.7 7.1 9.7 83 2.7 5.2 3.2 2 1 1 3 3 3 0 PepSY-associated TM region Fis1_TPR_C PF14853.6 CBY22179.1 - 3.6e-18 65.4 1.2 1.1e-17 63.8 0.8 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CBY22179.1 - 1e-10 41.1 0.1 2e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 CBY22179.1 - 0.012 15.7 0.1 0.089 13.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Mab-21 PF03281.14 CBY22179.1 - 0.81 8.9 3.2 5.2 6.3 0.1 2.0 1 1 0 2 2 2 0 Mab-21 protein PH PF00169.29 CBY22180.1 - 6e-24 84.6 1.0 1.9e-11 44.4 0.1 3.2 3 0 0 3 3 3 2 PH domain RhoGEF PF00621.20 CBY22180.1 - 2.8e-19 70.1 0.5 6.3e-19 68.9 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain FERM_C PF09380.10 CBY22180.1 - 3.6e-15 56.1 0.5 1e-14 54.7 0.1 2.0 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CBY22180.1 - 3.8e-14 52.4 0.0 8e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 CBY22180.1 - 1.7e-11 44.0 3.1 4.5e-11 42.7 3.1 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 CBY22180.1 - 3.4e-09 37.1 0.1 1.4e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 FERM central domain PH_9 PF15410.6 CBY22180.1 - 0.12 12.8 0.7 2.3 8.6 0.3 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain Sin3a_C PF16879.5 CBY22181.1 - 7.2e-47 160.5 1.5 7.2e-47 160.5 1.5 3.0 5 1 1 6 6 6 1 C-terminal domain of Sin3a protein PAH PF02671.21 CBY22181.1 - 8.4e-35 118.7 3.0 2e-14 53.5 0.0 4.4 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CBY22181.1 - 2e-31 108.0 0.1 5e-31 106.7 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor EFTUD2 PF16004.5 CBY22181.1 - 0.01 16.4 1.5 0.21 12.1 0.0 3.7 3 1 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus tRNA_NucTran2_2 PF13735.6 CBY22181.1 - 0.1 12.6 2.1 4.2 7.3 0.1 3.2 2 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Clr5 PF14420.6 CBY22181.1 - 0.26 11.5 1.6 0.79 10.0 0.1 2.7 3 0 0 3 3 3 0 Clr5 domain Endonuclease_NS PF01223.23 CBY22182.1 - 1.1e-21 77.7 2.0 1.4e-21 77.3 2.0 1.3 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 CBY22182.1 - 0.081 13.0 0.2 0.18 11.9 0.2 1.6 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Metallophos PF00149.28 CBY22183.1 - 1.8e-11 44.9 1.0 3.2e-11 44.1 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATPase_2 PF01637.18 CBY22183.1 - 0.0071 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Metallophos_3 PF14582.6 CBY22183.1 - 0.026 13.9 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily LRR_8 PF13855.6 CBY22184.1 - 1.8e-60 200.5 47.9 1.9e-12 46.7 1.0 8.9 3 3 6 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 CBY22184.1 - 8e-25 86.5 51.6 1.9e-06 28.1 1.6 10.0 5 2 7 12 12 12 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY22184.1 - 3e-22 78.9 14.1 6.4e-09 35.8 2.2 4.8 2 2 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY22184.1 - 2.5e-10 40.1 22.4 0.00087 18.8 0.7 6.2 2 2 4 6 6 6 4 Leucine-rich repeat LRR_1 PF00560.33 CBY22184.1 - 0.059 13.9 41.3 2.4 9.0 0.3 12.0 12 2 1 13 13 13 0 Leucine Rich Repeat Pkinase PF00069.25 CBY22185.1 - 1.1e-70 238.0 0.0 1.3e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22185.1 - 2.1e-36 125.6 0.0 2.8e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY22185.1 - 0.0004 19.5 0.1 0.0033 16.4 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY22185.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY22185.1 - 0.0087 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 CBY22185.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Exonuc_VII_L PF02601.15 CBY22186.1 - 0.0063 16.1 1.8 0.0081 15.8 1.8 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit FGAR-AT_N PF18076.1 CBY22186.1 - 0.028 14.4 0.3 0.053 13.5 0.3 1.4 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Apolipoprotein PF01442.18 CBY22186.1 - 0.057 13.3 4.7 0.12 12.2 4.7 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SKA2 PF16740.5 CBY22186.1 - 0.086 12.6 7.6 0.094 12.5 4.4 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4407 PF14362.6 CBY22186.1 - 0.095 12.0 2.6 0.13 11.6 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CBY22186.1 - 0.15 10.0 2.2 0.16 9.9 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ima1_N PF09779.9 CBY22186.1 - 0.29 12.0 2.3 1.1 10.1 2.3 1.9 1 1 0 1 1 1 0 Ima1 N-terminal domain Phasin PF05597.11 CBY22186.1 - 1 9.4 6.3 4 7.4 5.2 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2408 PF10303.9 CBY22186.1 - 1.1 9.8 7.8 4.8 7.7 7.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TMPIT PF07851.13 CBY22186.1 - 1.4 8.1 4.4 2.1 7.5 4.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein MerR-DNA-bind PF09278.11 CBY22186.1 - 3.3 8.3 5.4 1.6 9.3 0.1 2.5 2 1 0 2 2 2 0 MerR, DNA binding Uds1 PF15456.6 CBY22186.1 - 6.2 7.0 9.8 2.3 8.4 0.2 2.4 2 1 1 3 3 3 0 Up-regulated During Septation ING PF12998.7 CBY22186.1 - 7.2 7.3 9.4 8.3 7.1 7.9 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Bac_small_YrzI PF09501.10 CBY22188.1 - 1.4 9.1 6.5 1.4 9.2 1.3 2.3 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) EGF_3 PF12947.7 CBY22189.1 - 0.00056 20.1 6.2 0.0011 19.1 6.2 1.4 1 0 0 1 1 1 1 EGF domain Orf78 PF06024.12 CBY22189.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Get5_C PF18514.1 CBY22189.1 - 0.014 15.1 0.1 0.064 13.0 0.0 2.2 2 0 0 2 2 2 0 Get5 C-terminal domain DUF4051 PF13260.6 CBY22189.1 - 0.018 14.8 0.8 0.041 13.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) EGF PF00008.27 CBY22189.1 - 0.44 10.9 4.0 0.76 10.1 4.0 1.4 1 0 0 1 1 1 0 EGF-like domain cEGF PF12662.7 CBY22189.1 - 0.46 10.5 2.8 0.32 11.0 0.7 1.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CBY22189.1 - 1 9.7 4.6 2.1 8.7 4.6 1.5 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_CA PF07645.15 CBY22189.1 - 2.4 8.4 7.3 4.3 7.6 7.3 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY22189.1 - 4.9 7.5 7.4 8.6 6.7 7.4 1.4 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site VWA PF00092.28 CBY22190.1 - 1.1e-33 116.9 1.1 1.6e-33 116.4 0.2 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain fn3 PF00041.21 CBY22190.1 - 8.3e-28 96.6 6.3 1.5e-05 25.3 0.1 7.9 7 1 2 9 9 9 5 Fibronectin type III domain VWA_2 PF13519.6 CBY22190.1 - 1.4e-10 41.8 0.0 3.5e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_hydro_9 PF00759.19 CBY22191.1 - 1.2e-120 403.7 2.5 1.5e-120 403.4 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 CBY22191.1 - 6.4e-10 39.3 1.1 6.4e-10 39.3 1.1 1.9 2 0 0 2 2 2 1 Cellulose binding domain SSF PF00474.17 CBY22192.1 - 4.2e-106 355.2 18.2 7e-106 354.5 18.2 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family UNC-93 PF05978.16 CBY22192.1 - 2.4e-12 46.9 15.2 1.7e-10 40.8 7.3 3.6 3 1 1 4 4 4 2 Ion channel regulatory protein UNC-93 DUF3671 PF12420.8 CBY22195.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function Tubulin PF00091.25 CBY22196.1 - 3.9e-68 229.5 0.0 5.4e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY22196.1 - 2e-52 176.7 0.0 3.1e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY22196.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain TMEM51 PF15345.6 CBY22198.1 - 0.016 15.1 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 DUF3671 PF12420.8 CBY22198.1 - 0.24 11.5 6.7 18 5.5 2.0 3.6 2 1 1 3 3 3 0 Protein of unknown function Pkinase_Tyr PF07714.17 CBY22199.1 - 2.2e-60 204.2 0.0 3.7e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 CBY22199.1 - 4.8e-54 183.1 2.7 8.2e-54 182.3 2.7 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 CBY22199.1 - 4.1e-28 98.5 0.0 7e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 CBY22199.1 - 3.4e-19 69.0 0.0 5e-09 36.4 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain SAM_2 PF07647.17 CBY22199.1 - 2.3e-11 43.6 0.0 2.7e-10 40.2 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY22199.1 - 6.3e-10 39.4 0.0 1.2e-08 35.3 0.0 3.1 5 0 0 5 5 5 1 SAM domain (Sterile alpha motif) Pur_ac_phosph_N PF16656.5 CBY22199.1 - 0.01 16.4 0.1 11 6.7 0.1 2.8 1 1 1 2 2 2 0 Purple acid Phosphatase, N-terminal domain SAM_KSR1 PF13543.6 CBY22199.1 - 0.045 13.9 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 cEGF PF12662.7 CBY22199.1 - 0.78 9.7 4.2 7.8 6.5 0.4 3.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like SNAPc_SNAP43 PF09808.9 CBY22202.1 - 2.5e-20 73.3 2.1 2.7e-20 73.1 2.1 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Herpes_IE68 PF02479.16 CBY22202.1 - 0.093 12.3 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus immediate early protein IL2 PF00715.17 CBY22203.1 - 0.068 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Interleukin 2 CUB PF00431.20 CBY22204.1 - 4.7e-10 39.8 0.0 8.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 CUB domain TssO PF17561.2 CBY22204.1 - 0.11 12.5 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO PP2 PF14299.6 CBY22205.1 - 7.3e-06 26.1 1.1 2.2e-05 24.5 1.1 1.7 1 1 0 1 1 1 1 Phloem protein 2 BACK PF07707.15 CBY22206.1 - 2.1e-08 34.2 0.9 1.7e-07 31.3 0.0 2.9 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 CBY22206.1 - 2.5e-07 30.9 0.0 1.2e-06 28.7 0.0 2.3 1 1 0 1 1 1 1 BTB/POZ domain Helicase_C PF00271.31 CBY22207.1 - 6.2e-10 39.4 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRICHOS PF04089.14 CBY22207.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 BRICHOS domain SNF2_N PF00176.23 CBY22208.1 - 4.9e-50 170.2 0.3 1.1e-49 169.0 0.3 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 CBY22208.1 - 3.6e-10 40.1 0.0 2.3e-09 37.5 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBY22208.1 - 0.00052 19.7 0.1 0.072 12.8 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase CobA_CobO_BtuR PF02572.15 CBY22208.1 - 0.025 14.9 0.0 0.62 10.3 0.0 2.8 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Asp-B-Hydro_N PF05279.11 CBY22208.1 - 0.032 14.3 5.7 0.056 13.5 5.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GTP-bdg_M PF16360.5 CBY22208.1 - 1.5 9.5 10.6 1.7 9.3 0.0 3.4 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region Pkinase PF00069.25 CBY22209.1 - 1.4e-67 227.8 0.0 1.9e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22209.1 - 1.4e-28 99.9 0.0 1.8e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY22209.1 - 1.4e-08 34.5 0.0 1.5e-06 27.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like FTA2 PF13095.6 CBY22209.1 - 2.3e-05 24.1 0.0 0.2 11.2 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBY22209.1 - 0.00033 19.5 0.3 0.0011 17.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CBY22209.1 - 0.00074 18.9 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY22209.1 - 0.0039 17.2 0.1 0.72 9.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY22209.1 - 0.051 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase MARVEL PF01284.23 CBY22210.1 - 0.048 13.7 0.3 0.075 13.1 0.3 1.3 1 0 0 1 1 1 0 Membrane-associating domain ECF-ribofla_trS PF07155.12 CBY22210.1 - 0.058 13.4 0.2 0.082 12.9 0.2 1.3 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component Kunitz_BPTI PF00014.23 CBY22211.1 - 4.7e-10 39.5 3.9 4.7e-10 39.5 3.9 2.4 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Trefoil PF00088.18 CBY22211.1 - 0.016 15.1 7.4 0.016 15.1 7.4 4.0 4 1 0 4 4 4 0 Trefoil (P-type) domain Porphobil_deam PF01379.20 CBY22212.1 - 4.6e-71 238.5 1.4 6.2e-71 238.1 1.4 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CBY22212.1 - 8.4e-17 61.3 0.3 9.4e-16 58.0 0.0 2.8 3 0 0 3 3 3 1 Porphobilinogen deaminase, C-terminal domain Mito_carr PF00153.27 CBY22213.1 - 6.5e-41 138.2 4.0 3.6e-17 62.1 0.0 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein Glutaminase PF04960.15 CBY22214.1 - 2.9e-32 112.0 0.0 3.9e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Glutaminase GST_C_2 PF13410.6 CBY22216.1 - 3.2e-07 30.3 0.0 1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CBY22216.1 - 0.079 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY22216.1 - 0.08 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1674 PF07896.12 CBY22217.1 - 0.048 14.1 1.8 0.08 13.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) Pox_A21 PF05323.12 CBY22221.1 - 0.12 13.0 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A21 Protein Bac_RepA_C PF18008.1 CBY22221.1 - 0.19 12.1 0.4 0.35 11.3 0.0 1.6 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain LRR_8 PF13855.6 CBY22222.1 - 7.9e-39 131.2 38.0 1.9e-10 40.4 9.9 7.5 3 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 CBY22222.1 - 5.4e-24 83.9 52.6 1.2e-06 28.7 1.9 9.4 5 2 6 11 11 11 9 Leucine Rich repeats (2 copies) PDZ PF00595.24 CBY22222.1 - 5.3e-15 55.5 1.2 9.3e-13 48.3 0.4 2.6 2 0 0 2 2 2 1 PDZ domain LRR_9 PF14580.6 CBY22222.1 - 3.4e-09 36.4 21.2 0.0082 15.7 0.3 5.4 1 1 3 5 5 5 4 Leucine-rich repeat PDZ_6 PF17820.1 CBY22222.1 - 1.4e-07 31.2 0.3 3e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 PDZ domain LRR_5 PF13306.6 CBY22222.1 - 2.1e-06 27.7 1.8 0.0014 18.6 0.0 2.9 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) PDZ_2 PF13180.6 CBY22222.1 - 0.0024 18.1 0.0 0.006 16.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain LRR_6 PF13516.6 CBY22222.1 - 0.0026 17.7 22.8 2.1 8.6 1.5 7.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 CBY22222.1 - 0.07 13.7 31.2 12 6.9 1.1 9.3 10 1 0 10 10 10 0 Leucine Rich Repeat Vhr1 PF04001.13 CBY22222.1 - 0.27 11.6 1.9 0.89 9.9 0.2 2.6 2 0 0 2 2 2 0 Transcription factor Vhr1 NRDE-2 PF08424.10 CBY22223.1 - 8.5e-17 61.3 1.3 2.3e-13 50.0 0.2 2.6 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference NRDE-2 PF08424.10 CBY22224.1 - 4.3e-31 108.2 1.0 7.8e-31 107.4 1.0 1.3 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference MIR PF02815.19 CBY22224.1 - 0.18 11.6 1.2 0.3 10.9 0.6 1.5 1 1 0 1 1 1 0 MIR domain DUF1043 PF06295.12 CBY22224.1 - 1.9 8.5 6.0 0.92 9.5 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Mito_carr PF00153.27 CBY22225.1 - 1.6e-57 191.4 4.7 1.2e-19 70.0 0.3 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 CBY22225.1 - 2.3e-11 42.4 7.6 0.0018 17.7 0.0 4.5 4 1 1 5 5 5 3 EF hand EF-hand_7 PF13499.6 CBY22225.1 - 4.1e-11 43.2 4.1 1.4e-06 28.6 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY22225.1 - 1.7e-09 37.4 7.6 0.0069 16.2 0.2 4.5 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 CBY22225.1 - 2.7e-08 33.1 3.6 0.32 11.0 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CBY22225.1 - 0.00021 20.6 12.4 0.98 9.0 0.1 4.6 5 0 0 5 5 5 3 EF hand Serine_protease PF18405.1 CBY22225.1 - 0.03 13.5 0.0 0.074 12.2 0.0 1.6 1 0 0 1 1 1 0 Gammaproteobacterial serine protease EF-hand_10 PF14788.6 CBY22225.1 - 0.12 12.3 2.2 9 6.3 0.1 3.0 2 1 1 3 3 3 0 EF hand CAP160 PF07918.11 CBY22226.1 - 0.39 10.5 2.9 17 5.2 0.3 2.6 2 0 0 2 2 2 0 CAP160 repeat Thioredoxin_4 PF13462.6 CBY22228.1 - 8.2e-09 35.8 0.0 1.1e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 CBY22228.1 - 1.7e-07 31.2 0.0 0.0084 15.9 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain IpgD PF05925.12 CBY22228.1 - 0.023 13.3 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Arteri_GP4 PF02497.15 CBY22228.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Arterivirus glycoprotein SURF4 PF02077.15 CBY22229.1 - 1.9e-39 135.9 5.0 2.2e-39 135.7 5.0 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 CBY22229.1 - 0.16 12.6 0.1 0.16 12.6 0.1 3.1 2 1 1 3 3 3 0 DoxX Tht1 PF04163.12 CBY22229.1 - 0.22 10.3 3.6 0.31 9.7 3.6 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF3486 PF11985.8 CBY22231.1 - 0.077 13.4 0.8 7.4 7.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3486) Peptidase_S8 PF00082.22 CBY22233.1 - 3e-45 154.7 3.8 3.9e-45 154.4 3.8 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY22233.1 - 2.2e-25 88.5 0.2 6.6e-25 86.9 0.0 1.9 2 0 0 2 2 2 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 CBY22233.1 - 0.073 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Subtilase family DAGK_acc PF00609.19 CBY22234.1 - 2.2e-47 161.4 0.0 4.3e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBY22234.1 - 1.6e-24 85.9 0.0 8.6e-24 83.6 0.0 2.2 3 0 0 3 3 3 1 Diacylglycerol kinase catalytic domain I-set PF07679.16 CBY22236.1 - 9.7e-49 163.4 6.3 5.6e-18 64.8 0.0 7.7 8 0 0 8 8 8 7 Immunoglobulin I-set domain fn3 PF00041.21 CBY22236.1 - 5e-35 119.7 0.5 9.3e-12 45.1 0.0 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.6 CBY22236.1 - 1.1e-29 102.9 0.1 8.9e-10 39.0 0.0 6.7 7 0 0 7 7 7 5 Immunoglobulin domain Ig_2 PF13895.6 CBY22236.1 - 5.8e-17 61.8 0.1 5.6e-07 29.8 0.0 5.9 5 1 1 6 6 6 3 Immunoglobulin domain ig PF00047.25 CBY22236.1 - 1.4e-15 57.2 0.1 4.6e-09 36.3 0.0 5.2 5 0 0 5 5 5 2 Immunoglobulin domain THB PF18362.1 CBY22236.1 - 1.1e-10 40.8 0.2 2.6e-10 39.7 0.2 1.6 1 0 0 1 1 1 1 Tri-helix bundle domain V-set PF07686.17 CBY22236.1 - 1.1e-08 35.2 0.4 0.2 11.9 0.0 6.5 5 2 0 5 5 5 2 Immunoglobulin V-set domain SusE PF14292.6 CBY22236.1 - 0.00077 19.7 3.9 3.7 7.8 0.0 5.5 6 0 0 6 6 6 1 SusE outer membrane protein Herpes_gE PF02480.16 CBY22236.1 - 0.048 12.4 0.3 13 4.4 0.0 3.3 3 1 0 3 3 3 0 Alphaherpesvirus glycoprotein E MBG_2 PF18676.1 CBY22236.1 - 0.68 10.6 12.5 6.9 7.4 1.4 5.5 5 1 0 5 5 5 0 MBG domain (YGX type) zf-C2H2 PF00096.26 CBY22237.1 - 1.1e-12 47.7 26.4 9.8e-05 22.6 2.7 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY22237.1 - 2.6e-10 40.2 22.4 0.0023 18.6 1.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY22237.1 - 2.9e-10 40.1 8.4 2.6e-06 27.6 0.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY22237.1 - 7.2e-06 25.9 20.4 0.00012 22.0 0.5 3.8 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY22237.1 - 0.0016 18.7 24.5 0.12 12.7 1.1 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 CBY22237.1 - 0.007 16.2 1.5 0.19 11.5 0.3 2.6 1 1 1 2 2 2 1 GAGA factor FYVE PF01363.21 CBY22237.1 - 0.011 15.9 6.4 0.011 15.9 6.4 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-AN1 PF01428.16 CBY22237.1 - 0.011 15.9 17.3 0.091 12.9 4.4 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger zf-met PF12874.7 CBY22237.1 - 0.013 15.9 19.1 0.035 14.5 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type C1_4 PF07975.12 CBY22237.1 - 0.11 12.7 11.1 4.3 7.6 0.2 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain DUF2757 PF10955.8 CBY22237.1 - 0.57 10.5 6.5 5.8 7.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2757) XPA_N PF01286.18 CBY22237.1 - 1 9.5 10.1 15 5.7 0.1 3.4 3 0 0 3 3 3 0 XPA protein N-terminal Prok-RING_1 PF14446.6 CBY22237.1 - 1 9.3 8.3 12 5.9 0.2 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_8 PF15909.5 CBY22237.1 - 2.6 8.4 13.7 0.23 11.8 4.4 2.6 2 1 1 3 3 3 0 C2H2-type zinc ribbon PyrI_C PF02748.15 CBY22237.1 - 3 7.8 10.2 4.9 7.1 0.4 3.4 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.7 CBY22237.1 - 5.4 7.4 21.1 7.2 7.0 0.8 3.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 CBY22237.1 - 7 6.9 8.7 29 4.9 2.5 2.7 2 1 0 2 2 2 0 Zinc ribbon domain Choline_transpo PF04515.12 CBY22238.1 - 1.2e-81 274.5 33.5 1.2e-81 274.5 33.5 2.8 3 0 0 3 3 3 2 Plasma-membrane choline transporter Apo-VLDL-II PF05418.11 CBY22238.1 - 0.011 16.2 0.0 0.037 14.6 0.0 1.8 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) CoA_transf_3 PF02515.17 CBY22239.1 - 1.1e-68 232.0 0.0 1.9e-68 231.3 0.0 1.3 1 1 0 1 1 1 1 CoA-transferase family III FDF PF09532.10 CBY22240.1 - 4.3e-05 24.3 0.9 4.3e-05 24.3 0.9 2.0 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.7 CBY22240.1 - 0.076 13.1 0.4 6.7 6.9 0.1 2.7 2 0 0 2 2 2 0 Scd6-like Sm domain Pkinase PF00069.25 CBY22241.1 - 1.1e-62 211.8 0.0 1.5e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22241.1 - 3.1e-32 111.9 0.0 4.8e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 CBY22241.1 - 1.3e-11 44.8 1.0 3.2e-11 43.5 0.6 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase_fungal PF17667.1 CBY22241.1 - 7e-05 21.8 0.0 9e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY22241.1 - 0.032 13.5 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RhoGAP PF00620.27 CBY22243.1 - 1.9e-28 99.2 0.0 3.6e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.18 CBY22243.1 - 4.9e-06 26.4 3.1 1.1e-05 25.2 3.1 1.6 1 0 0 1 1 1 1 BAR domain RBD-FIP PF09457.10 CBY22245.1 - 1.4e-05 24.9 0.9 1.4e-05 24.9 0.9 2.8 3 0 0 3 3 3 1 FIP domain THOC7 PF05615.13 CBY22245.1 - 0.0012 19.1 18.3 0.0012 19.1 18.3 3.8 1 1 2 4 4 4 1 Tho complex subunit 7 DUF724 PF05266.14 CBY22245.1 - 0.55 10.0 42.9 0.47 10.2 3.9 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF724) HOOK PF05622.12 CBY22245.1 - 0.57 8.3 56.6 0.073 11.2 18.6 2.7 1 1 1 2 2 2 0 HOOK protein SNCAIP_SNCA_bd PF16700.5 CBY22245.1 - 0.97 9.2 7.7 0.084 12.6 1.5 2.5 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain DUF357 PF04010.13 CBY22245.1 - 1 9.5 3.2 7.6 6.7 0.2 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF357) Jnk-SapK_ap_N PF09744.9 CBY22245.1 - 3.2 8.0 59.8 2.1 8.6 2.6 4.4 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Filament PF00038.21 CBY22245.1 - 4.1 6.9 52.9 3.3 7.2 12.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein APG6_N PF17675.1 CBY22245.1 - 4.8 7.7 61.7 19 5.8 18.3 4.5 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 CBY22245.1 - 6.8 5.5 55.1 7 5.4 32.1 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 CBY22245.1 - 7.5 7.5 49.9 2.5 9.0 16.2 3.8 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF2935 PF11155.8 CBY22245.1 - 9.9 6.5 19.6 2.8 8.3 3.6 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF2935) CEP63 PF17045.5 CBY22245.1 - 10 6.0 53.4 2.3e+02 1.5 42.5 2.4 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Metallophos PF00149.28 CBY22246.1 - 8.9e-26 91.7 0.0 1.8e-25 90.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBY22246.1 - 0.055 13.7 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PepSY_TM_like_2 PF16357.5 CBY22247.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.5 1 1 0 1 1 1 0 Putative PepSY_TM-like Snf7 PF03357.21 CBY22248.1 - 3.4e-13 49.6 16.1 4.2e-13 49.3 14.0 1.9 1 1 1 2 2 2 2 Snf7 Ist1 PF03398.14 CBY22248.1 - 1.7e-05 24.8 3.9 2.3e-05 24.4 3.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 CBY22248.1 - 0.055 13.1 0.2 0.12 12.0 0.1 1.6 1 1 1 2 2 2 0 Dimethlysulfonioproprionate lyase YlqD PF11068.8 CBY22248.1 - 0.12 12.8 11.2 1.2 9.5 0.4 2.3 1 1 0 2 2 2 0 YlqD protein DUF4363 PF14276.6 CBY22248.1 - 0.24 11.5 2.9 16 5.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) T2SSM PF04612.12 CBY22248.1 - 0.64 10.1 7.7 0.091 12.8 1.8 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M SNARE PF05739.19 CBY22248.1 - 1.4 9.0 3.8 7.7 6.6 0.5 3.3 2 1 1 3 3 3 0 SNARE domain YlbD_coat PF14071.6 CBY22248.1 - 4.1 7.7 7.3 0.42 10.9 1.0 2.2 1 1 1 2 2 2 0 Putative coat protein MARVEL PF01284.23 CBY22249.1 - 1.4e-24 86.7 6.0 2.6e-24 85.9 6.0 1.5 1 1 0 1 1 1 1 Membrane-associating domain PTPA PF03095.15 CBY22250.1 - 2.6e-104 348.9 0.0 2.9e-104 348.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF2203 PF09969.9 CBY22250.1 - 0.038 14.7 0.0 0.069 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) NIF PF03031.18 CBY22251.1 - 1.2e-26 93.3 0.2 2.1e-26 92.5 0.2 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 CBY22251.1 - 6.8e-07 28.9 0.1 1.2e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Mito_carr PF00153.27 CBY22252.1 - 2.3e-53 178.1 1.3 5.8e-19 67.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SIR2 PF02146.17 CBY22253.1 - 6.4e-56 189.1 0.0 9e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family BAR_3 PF16746.5 CBY22254.1 - 1e-55 189.1 15.3 1e-55 189.1 15.3 2.2 2 0 0 2 2 2 1 BAR domain of APPL family RhoGAP PF00620.27 CBY22254.1 - 2.4e-16 59.9 0.0 2.3e-09 37.2 0.0 3.0 1 1 1 2 2 2 2 RhoGAP domain PH PF00169.29 CBY22254.1 - 6.6e-07 29.8 3.4 6.2e-06 26.7 0.2 3.5 3 0 0 3 3 3 1 PH domain SH3_9 PF14604.6 CBY22254.1 - 6.3e-06 26.0 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY22254.1 - 0.0002 20.9 0.0 0.0006 19.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PBP_N PF17093.5 CBY22255.1 - 0.048 13.9 0.1 0.065 13.5 0.1 1.3 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus PBP_N PF17093.5 CBY22256.1 - 0.03 14.6 0.3 0.032 14.5 0.3 1.1 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus XhlA PF10779.9 CBY22256.1 - 3.5 7.9 6.3 8.8 6.6 2.8 2.1 2 0 0 2 2 2 0 Haemolysin XhlA BTB PF00651.31 CBY22257.1 - 0.005 17.0 0.1 0.0095 16.2 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ldh_1_N PF00056.23 CBY22258.1 - 1.4e-07 31.7 0.1 2.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBY22258.1 - 0.011 15.6 0.0 0.062 13.2 0.0 2.1 1 1 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sugar-bind PF04198.13 CBY22258.1 - 0.066 12.3 0.1 0.6 9.2 0.0 2.2 2 1 1 3 3 3 0 Putative sugar-binding domain Arm PF00514.23 CBY22259.1 - 6.6e-49 162.5 18.7 3.8e-08 33.1 0.3 11.6 12 0 0 12 12 12 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CBY22259.1 - 3.8e-08 33.6 10.1 0.00034 21.0 0.1 5.8 4 3 2 6 6 6 3 HEAT repeats HEAT PF02985.22 CBY22259.1 - 4.7e-08 32.6 1.5 0.87 10.0 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat KAP PF05804.12 CBY22259.1 - 8.8e-07 27.5 7.4 8.8e-07 27.5 7.4 3.3 2 2 2 5 5 5 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 CBY22259.1 - 4.6e-06 26.8 4.5 0.16 12.0 0.1 4.5 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 CBY22259.1 - 3.7e-05 23.7 1.2 0.00043 20.3 0.2 3.2 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.20 CBY22259.1 - 5.4e-05 21.9 14.1 0.13 10.8 0.0 4.8 2 1 1 3 3 3 1 Adaptin N terminal region Arm_2 PF04826.13 CBY22259.1 - 0.00015 21.3 9.9 0.076 12.5 0.0 3.5 2 1 2 4 4 4 2 Armadillo-like DUF3361 PF11841.8 CBY22259.1 - 0.00026 20.9 7.1 0.8 9.6 0.1 4.6 3 1 2 5 5 5 1 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 CBY22259.1 - 0.00054 20.4 9.9 2.3 8.8 0.0 6.9 7 1 1 8 8 8 1 HEAT-like repeat TetR_C_16 PF17920.1 CBY22259.1 - 0.014 15.6 0.2 3.4 7.9 0.0 3.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF3731 PF12531.8 CBY22259.1 - 0.055 13.3 4.6 0.22 11.3 0.1 3.6 4 0 0 4 4 4 0 DNA-K related protein RasGEF_N_2 PF14663.6 CBY22259.1 - 0.13 12.6 5.5 18 5.8 0.1 5.3 4 2 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTP1_C1 PF10363.9 CBY22259.1 - 0.57 10.4 6.0 9.7 6.4 0.0 4.6 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 CBY22259.1 - 0.57 10.3 7.3 59 3.8 0.1 5.0 3 1 4 7 7 7 0 V-ATPase subunit H DUF3397 PF11877.8 CBY22262.1 - 1.9 8.7 13.4 2.3 8.5 0.7 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF3397) PYNP_C PF07831.13 CBY22263.1 - 0.0064 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain zf-C2HE PF16278.5 CBY22263.1 - 0.0089 16.5 1.5 0.012 16.0 0.3 1.9 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger RNase_T PF00929.24 CBY22263.1 - 0.035 14.7 0.2 0.059 13.9 0.1 1.7 1 1 0 1 1 1 0 Exonuclease TIR_2 PF13676.6 CBY22263.1 - 0.077 13.6 0.1 0.19 12.3 0.0 1.8 1 1 0 1 1 1 0 TIR domain zf-C2H2_4 PF13894.6 CBY22263.1 - 0.14 13.1 2.9 0.42 11.6 2.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY22263.1 - 4.1 8.0 6.0 3 8.4 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Forkhead PF00250.18 CBY22264.1 - 1.9e-31 108.2 0.0 2.8e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Forkhead domain DUF2071 PF09844.9 CBY22264.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) C2 PF00168.30 CBY22265.1 - 1.2e-50 170.0 0.1 2.7e-22 79.0 0.0 3.3 3 0 0 3 3 3 3 C2 domain CEP76-C2 PF15627.6 CBY22265.1 - 1e-07 31.7 0.1 0.004 16.7 0.0 3.2 3 0 0 3 3 3 2 CEP76 C2 domain Reticulon PF02453.17 CBY22265.1 - 0.0047 16.9 1.1 0.01 15.8 1.1 1.5 1 0 0 1 1 1 1 Reticulon PRT_C PF08372.10 CBY22265.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 CBY22265.1 - 0.15 11.0 1.6 0.22 10.4 0.8 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin zf-RING_2 PF13639.6 CBY22266.1 - 1.7e-10 41.0 8.1 1.7e-10 41.0 8.1 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY22266.1 - 3.3e-07 30.0 7.0 8.1e-07 28.8 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY22266.1 - 1.2e-06 28.5 3.6 2.4e-06 27.4 3.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY22266.1 - 4.6e-06 26.4 7.3 4.6e-06 26.4 7.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY22266.1 - 5.9e-05 23.3 12.5 0.00013 22.2 11.1 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY22266.1 - 8.7e-05 22.3 4.4 8.7e-05 22.3 4.4 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY22266.1 - 0.00057 19.8 7.2 0.00057 19.8 7.2 1.7 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY22266.1 - 0.0013 18.5 4.2 0.0045 16.8 4.2 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 DUF1272 PF06906.11 CBY22266.1 - 0.0085 16.2 1.7 0.023 14.8 1.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-ANAPC11 PF12861.7 CBY22266.1 - 0.0092 16.0 4.3 0.027 14.5 4.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TBCA PF02970.16 CBY22266.1 - 0.0094 16.3 7.9 0.55 10.6 0.0 2.6 2 1 0 2 2 2 1 Tubulin binding cofactor A zf-RING_4 PF14570.6 CBY22266.1 - 0.011 15.6 5.8 0.03 14.1 5.8 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TMPIT PF07851.13 CBY22266.1 - 0.028 13.7 3.3 0.044 13.0 3.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein PknG_rubred PF16919.5 CBY22266.1 - 0.036 14.2 0.1 0.39 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain Pneumo_phosprot PF02478.16 CBY22266.1 - 0.038 13.6 1.5 0.038 13.6 1.5 2.3 1 1 1 2 2 2 0 Pneumovirus phosphoprotein Z1 PF10593.9 CBY22266.1 - 0.076 12.5 1.9 0.13 11.7 1.9 1.4 1 0 0 1 1 1 0 Z1 domain RPW8 PF05659.11 CBY22266.1 - 0.11 12.2 5.8 2.6 7.7 1.5 2.4 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 zf-RING_11 PF17123.5 CBY22266.1 - 0.12 12.1 8.1 0.088 12.6 4.7 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBY22266.1 - 0.61 10.3 6.5 1.7 8.8 5.8 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 CBY22266.1 - 1.5 9.0 7.1 4.3 7.5 7.1 1.9 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 CBY22266.1 - 1.6 8.9 9.0 51 4.1 9.0 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain SLATT_5 PF18160.1 CBY22266.1 - 1.8 7.8 5.2 3.9 6.8 1.2 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Cep57_CLD PF14073.6 CBY22266.1 - 2.3 8.2 11.1 0.76 9.8 8.4 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 zf-RING_10 PF16685.5 CBY22266.1 - 3.3 7.9 7.7 12 6.2 1.5 2.5 1 1 1 2 2 2 0 zinc RING finger of MSL2 PAX PF00292.18 CBY22267.1 - 5.1e-66 220.3 0.8 7.6e-66 219.7 0.8 1.2 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CBY22267.1 - 9.4e-24 83.0 6.4 1.6e-23 82.3 6.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY22267.1 - 9.5e-05 22.2 0.8 9.5e-05 22.2 0.8 2.3 3 0 0 3 3 3 1 Homeobox KN domain HTH_23 PF13384.6 CBY22267.1 - 0.00039 20.1 1.3 0.0051 16.6 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 CBY22267.1 - 0.006 16.6 0.1 0.029 14.4 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 CBY22267.1 - 0.17 12.0 0.6 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain EGF PF00008.27 CBY22268.1 - 8e-18 64.4 37.5 1.9e-08 34.5 7.5 3.7 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 CBY22268.1 - 5.8e-09 36.3 27.6 0.00085 19.9 5.8 3.8 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_2 PF07974.13 CBY22268.1 - 3e-07 30.7 40.9 8.1e-05 22.9 8.2 3.4 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 CBY22268.1 - 0.00058 20.0 37.5 0.028 14.6 9.1 3.8 4 0 0 4 4 4 3 EGF domain EGF_CA PF07645.15 CBY22268.1 - 0.021 15.0 34.3 2.4 8.4 7.5 3.5 2 1 1 3 3 3 0 Calcium-binding EGF domain Laminin_EGF PF00053.24 CBY22268.1 - 2.8 8.1 29.3 2.4 8.4 5.5 3.3 1 1 2 3 3 3 0 Laminin EGF domain Laminin_G_1 PF00054.23 CBY22271.1 - 0.00031 21.0 0.0 0.00044 20.5 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 CBY22271.1 - 0.0046 17.5 0.0 0.0067 17.0 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Trypsin PF00089.26 CBY22272.1 - 1e-56 192.2 1.6 4.9e-56 190.0 0.8 2.0 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY22272.1 - 0.00056 20.8 0.0 0.0012 19.7 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY22272.1 - 0.001 19.4 0.1 0.0023 18.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF4793 PF16041.5 CBY22272.1 - 0.31 11.2 3.4 1.5 9.0 1.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4793) TMEM164 PF14808.6 CBY22273.1 - 4.8e-86 288.2 7.2 5.6e-86 288.0 7.2 1.0 1 0 0 1 1 1 1 TMEM164 family Collagen PF01391.18 CBY22274.1 - 2.4e-121 395.5 497.8 1.7e-08 34.1 32.3 15.5 1 1 11 12 12 12 10 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CBY22274.1 - 6.4e-77 258.0 0.3 8.8e-77 257.5 0.3 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.18 CBY22274.1 - 2.7e-09 37.2 14.9 2.7e-09 37.2 14.9 1.7 2 0 0 2 2 2 1 von Willebrand factor type C domain Tmem26 PF09772.9 CBY22275.1 - 9.4e-75 251.6 1.4 6.6e-52 176.6 0.3 2.3 2 0 0 2 2 2 2 Transmembrane protein 26 Arylsulfotran_N PF17425.2 CBY22276.1 - 0.047 13.7 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain PMP22_Claudin PF00822.20 CBY22277.1 - 8.6e-10 38.7 4.4 3.4e-09 36.8 4.4 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY22277.1 - 5.3e-06 26.3 4.5 7.8e-05 22.5 4.5 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 CBY22277.1 - 0.0098 15.5 1.1 0.0098 15.5 1.1 2.1 2 1 0 2 2 2 1 SUR7/PalI family Prefoldin_2 PF01920.20 CBY22278.1 - 4.2e-19 68.5 3.9 4.8e-19 68.3 3.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 CBY22278.1 - 0.0034 17.9 0.3 0.08 13.6 0.0 2.1 2 0 0 2 2 2 1 SlyX HBM PF16591.5 CBY22278.1 - 0.025 14.0 0.1 0.045 13.2 0.0 1.5 1 1 0 1 1 1 0 Helical bimodular sensor domain SesA PF17107.5 CBY22278.1 - 0.026 14.7 0.3 0.033 14.4 0.3 1.1 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CCDC-167 PF15188.6 CBY22278.1 - 0.086 13.2 2.1 1.1 9.6 0.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ZapB PF06005.12 CBY22278.1 - 1.7 9.1 6.6 7.4 7.1 0.5 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Myotub-related PF06602.14 CBY22279.1 - 4e-49 167.5 5.2 1.4e-30 106.5 1.2 2.5 2 1 0 2 2 2 2 Myotubularin-like phosphatase domain InaF-motif PF15018.6 CBY22279.1 - 3e-11 43.0 3.8 6e-11 42.0 3.8 1.6 1 0 0 1 1 1 1 TRP-interacting helix PH PF00169.29 CBY22279.1 - 1.8e-09 38.0 0.3 6.4e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 CBY22279.1 - 0.0028 18.1 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Mlp PF03304.13 CBY22279.1 - 0.13 12.5 0.1 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 Mlp lipoprotein family GRAM PF02893.20 CBY22280.1 - 5.1e-13 48.9 0.0 7.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 GRAM domain DUF1249 PF06853.12 CBY22280.1 - 0.058 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) Acetyltransf_1 PF00583.25 CBY22281.1 - 0.0015 18.8 0.0 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY22281.1 - 0.0096 15.9 0.0 0.05 13.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY22281.1 - 0.033 14.2 0.0 0.078 13.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY22281.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LTXXQ PF07813.12 CBY22282.1 - 0.0016 19.1 12.4 0.0016 19.1 12.4 3.0 1 1 2 3 3 3 1 LTXXQ motif family protein PulG PF11773.8 CBY22282.1 - 0.78 9.6 4.7 1 9.3 0.0 2.7 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin PP2C PF00481.21 CBY22283.1 - 4.6e-05 23.2 0.0 5.8e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 CBY22284.1 - 0.00016 22.1 0.1 0.00032 21.1 0.0 1.5 2 0 0 2 2 2 1 Protein serine/threonine phosphatase 2C, C-terminal domain SIR2 PF02146.17 CBY22285.1 - 1.1e-58 198.1 0.0 1.8e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CBY22285.1 - 0.00076 19.2 0.0 0.75 9.5 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 CBY22285.1 - 0.065 13.0 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) AAA_26 PF13500.6 CBY22285.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 CBY22286.1 - 2.7e-41 142.3 0.0 3.3e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBY22286.1 - 2.4e-22 79.1 0.5 4.8e-22 78.1 0.5 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TRIQK PF15168.6 CBY22288.1 - 6.1e-36 122.2 0.0 6.5e-36 122.1 0.0 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family Ureide_permease PF07168.11 CBY22288.1 - 0.059 12.1 0.0 0.063 12.0 0.0 1.0 1 0 0 1 1 1 0 Ureide permease Orf78 PF06024.12 CBY22288.1 - 0.11 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) WH1 PF00568.23 CBY22289.1 - 5.6e-19 68.1 0.0 9.5e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CBY22289.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 WH2 motif ABC_tran PF00005.27 CBY22290.1 - 1.1e-35 123.1 0.0 2.7e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CBY22290.1 - 3.9e-33 115.3 4.2 5.6e-33 114.8 4.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CBY22290.1 - 4.1e-06 26.4 2.2 1.9e-05 24.2 0.1 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CBY22290.1 - 0.0071 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 CBY22290.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY22290.1 - 0.025 15.0 0.0 0.068 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 CBY22290.1 - 0.025 14.7 0.2 0.089 12.9 0.2 1.9 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 CBY22290.1 - 0.034 14.4 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBY22290.1 - 0.035 13.9 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBY22290.1 - 0.036 14.1 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CBY22290.1 - 0.041 14.1 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CBY22290.1 - 0.091 12.7 0.1 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF2207 PF09972.9 CBY22290.1 - 0.097 11.4 0.2 0.22 10.2 0.1 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ATP_bind_1 PF03029.17 CBY22290.1 - 0.15 11.8 0.5 16 5.2 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 CBY22290.1 - 0.17 12.2 0.6 4.1 7.7 0.2 2.7 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 CBY22290.1 - 0.2 12.1 1.6 1.6 9.1 0.1 3.0 3 1 0 3 3 3 0 RNA helicase RTTN_N PF14726.6 CBY22291.1 - 6.7e-18 65.3 0.0 6.7e-18 65.3 0.0 3.8 4 0 0 4 4 4 1 Rotatin, an armadillo repeat protein, centriole functioning HEAT PF02985.22 CBY22291.1 - 0.077 13.3 0.1 4.2 7.9 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Nipped-B_C PF12830.7 CBY22291.1 - 2.7 7.9 8.7 1.1 9.1 0.0 3.9 3 1 0 3 3 3 0 Sister chromatid cohesion C-terminus Kinesin PF00225.23 CBY22292.1 - 1.9e-105 352.5 3.6 3.9e-105 351.5 3.6 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY22292.1 - 1.2e-46 158.3 0.1 2.7e-46 157.2 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding Sec34 PF04136.15 CBY22292.1 - 0.0016 18.4 12.8 0.059 13.3 2.5 2.5 1 1 1 2 2 2 2 Sec34-like family MAD PF05557.13 CBY22292.1 - 0.0055 15.1 23.3 0.011 14.1 23.3 1.4 1 0 0 1 1 1 1 Mitotic checkpoint protein TPR_MLP1_2 PF07926.12 CBY22292.1 - 0.019 15.0 27.1 0.056 13.5 27.1 1.9 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CBY22292.1 - 0.019 15.0 13.0 0.28 11.2 3.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 CBY22292.1 - 0.036 14.1 10.0 0.12 12.3 10.0 2.0 1 1 0 1 1 1 0 Laminin Domain II GAS PF13851.6 CBY22292.1 - 0.07 12.5 31.5 0.45 9.8 30.2 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 CBY22292.1 - 0.19 11.0 24.6 0.6 9.4 10.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prominin PF05478.11 CBY22292.1 - 0.21 9.5 8.9 0.32 8.9 8.9 1.2 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 CBY22292.1 - 0.29 10.0 30.3 0.2 10.5 17.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 CBY22292.1 - 0.3 10.7 28.4 0.11 12.1 22.8 2.8 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FlaC_arch PF05377.11 CBY22292.1 - 0.31 11.4 15.6 0.32 11.4 2.8 3.9 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Nup88 PF10168.9 CBY22292.1 - 0.74 7.6 17.9 1.1 7.0 17.9 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF16 PF01519.16 CBY22292.1 - 0.78 10.3 22.8 5.2 7.6 17.8 3.4 3 1 0 3 3 2 0 Protein of unknown function DUF16 HIP1_clath_bdg PF16515.5 CBY22292.1 - 0.83 10.3 26.2 0.75 10.4 11.8 3.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 CBY22292.1 - 0.89 9.1 20.9 0.024 14.2 13.7 1.9 2 1 0 2 2 2 0 Exonuclease VII, large subunit TolA_bind_tri PF16331.5 CBY22292.1 - 1 9.5 19.6 0.028 14.5 5.3 2.9 1 1 0 2 2 2 0 TolA binding protein trimerisation Laminin_I PF06008.14 CBY22292.1 - 1.2 8.8 24.3 0.13 11.9 6.1 2.7 2 1 1 3 3 2 0 Laminin Domain I WXG100 PF06013.12 CBY22292.1 - 1.3 9.3 9.1 6.5 7.1 2.7 3.4 2 1 0 3 3 2 0 Proteins of 100 residues with WXG MetOD2 PF18548.1 CBY22292.1 - 1.4 9.0 12.9 1.4 9.1 1.1 3.3 2 1 1 3 3 3 0 Metanogen output domain 2 DUF948 PF06103.11 CBY22292.1 - 1.5 9.1 6.8 15 5.9 1.2 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.11 CBY22292.1 - 1.9 7.2 31.4 4.6 6.0 27.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF812) DUF2968 PF11180.8 CBY22292.1 - 2.1 8.0 19.3 3.6 7.2 7.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4407 PF14362.6 CBY22292.1 - 2.4 7.4 19.5 0.9 8.8 16.9 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CBY22292.1 - 2.6 8.6 37.1 0.46 11.0 18.4 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 CBY22292.1 - 2.9 8.0 29.9 0.58 10.3 10.2 3.5 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 COG2 PF06148.11 CBY22292.1 - 3.1 7.9 12.3 3.6 7.7 2.1 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 CBY22292.1 - 3.2 7.6 15.4 0.31 10.9 1.9 3.8 3 1 0 4 4 3 0 Sec8 exocyst complex component specific domain ERM PF00769.19 CBY22292.1 - 3.2 7.5 38.9 0.16 11.8 28.9 2.7 2 1 1 3 3 3 0 Ezrin/radixin/moesin family LXG PF04740.12 CBY22292.1 - 3.5 7.3 18.0 3.1 7.4 3.2 2.7 1 1 1 2 2 2 0 LXG domain of WXG superfamily Occludin_ELL PF07303.13 CBY22292.1 - 3.5 8.4 18.9 11 6.9 6.1 3.1 2 1 1 3 3 2 0 Occludin homology domain Sec20 PF03908.13 CBY22292.1 - 4.2 7.4 6.6 7.2 6.6 0.7 3.0 2 0 0 2 2 2 0 Sec20 KxDL PF10241.9 CBY22292.1 - 4.6 7.6 22.4 2.4 8.5 6.4 3.2 2 1 2 4 4 3 0 Uncharacterized conserved protein Bacillus_HBL PF05791.11 CBY22292.1 - 4.7 7.0 11.5 1.4 8.7 6.1 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SHE3 PF17078.5 CBY22292.1 - 5.4 6.7 24.8 2.5 7.7 18.5 2.9 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 CBY22292.1 - 8.7 4.1 20.4 28 2.4 20.4 2.0 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 CBY22292.1 - 9.8 4.6 24.8 5.9 5.4 12.4 2.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A HMG_CoA_synt_C PF08540.10 CBY22293.1 - 0.026 14.2 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal zf-C3HC PF07967.13 CBY22293.1 - 0.027 14.5 1.2 0.06 13.4 0.8 1.7 1 1 1 2 2 2 0 C3HC zinc finger-like UPAR_LY6 PF00021.21 CBY22293.1 - 0.35 11.6 7.5 1.1 10.1 7.5 1.8 1 1 0 1 1 1 0 u-PAR/Ly-6 domain MDD_C PF18376.1 CBY22294.1 - 0.15 11.7 1.4 0.23 11.2 0.1 1.7 1 1 1 2 2 2 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain Paf1 PF03985.13 CBY22294.1 - 0.46 9.4 10.3 0.5 9.3 10.3 1.0 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 CBY22294.1 - 1.7 7.9 8.4 2.1 7.6 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 CBY22294.1 - 2 7.4 14.8 2.3 7.2 14.8 1.1 1 0 0 1 1 1 0 Pes-10 Nop14 PF04147.12 CBY22294.1 - 3.2 5.8 15.2 3.7 5.7 15.2 1.0 1 0 0 1 1 1 0 Nop14-like family Pep_M12B_propep PF01562.19 CBY22296.1 - 1.8e-28 99.5 1.1 3.5e-28 98.6 1.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 CBY22296.1 - 3.2e-20 72.9 0.1 6.8e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 CBY22296.1 - 8.5e-15 55.0 6.8 8.5e-15 55.0 6.8 5.4 6 1 0 6 6 6 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 CBY22296.1 - 1.3e-14 54.8 0.4 3.4e-14 53.5 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 TSP_1 PF00090.19 CBY22296.1 - 6.3e-12 45.5 82.7 6.5e-06 26.3 8.9 8.3 8 1 0 8 8 8 5 Thrombospondin type 1 domain Reprolysin_4 PF13583.6 CBY22296.1 - 1.5e-07 31.2 0.2 2.8e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CBY22296.1 - 1.8e-07 31.7 0.4 3.4e-07 30.8 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CBY22296.1 - 6.3e-07 29.5 0.3 1.1e-06 28.7 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 CBY22296.1 - 6.5e-06 26.8 4.9 4e-05 24.3 4.9 2.6 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Peptidase_M57 PF12388.8 CBY22296.1 - 0.14 11.8 0.3 0.3 10.7 0.3 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF2442 PF10387.9 CBY22297.1 - 0.15 12.4 0.0 16 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Pkinase PF00069.25 CBY22298.1 - 7.3e-36 123.9 0.0 1.5e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22298.1 - 2e-30 105.9 0.0 3.5e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CBY22298.1 - 1.6e-23 82.2 36.8 1.5e-06 27.8 3.6 7.2 7 1 0 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 CBY22298.1 - 3.4e-17 62.3 48.9 0.00053 20.3 0.8 8.5 7 2 2 9 9 8 6 Leucine Rich repeats (2 copies) COR PF16095.5 CBY22298.1 - 1.2e-13 51.3 0.0 6.9e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 CBY22298.1 - 1.1e-09 38.5 0.0 3.3e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Kinase-like PF14531.6 CBY22298.1 - 0.0013 18.1 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like AAA_18 PF13238.6 CBY22298.1 - 0.0072 16.9 0.0 0.16 12.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CBY22298.1 - 0.014 15.5 0.0 7.6 6.7 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain LRR_9 PF14580.6 CBY22298.1 - 0.018 14.6 15.6 0.77 9.2 1.3 4.4 3 2 1 4 4 4 0 Leucine-rich repeat DUF5344 PF17279.2 CBY22298.1 - 0.1 13.2 0.6 93 3.7 0.0 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5344) AAA_16 PF13191.6 CBY22298.1 - 0.12 12.8 0.8 0.92 9.9 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CBY22298.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CBY22298.1 - 0.16 12.5 0.0 0.61 10.6 0.0 2.0 2 0 0 2 2 1 0 ABC transporter LRR_1 PF00560.33 CBY22298.1 - 0.24 12.1 35.3 0.46 11.2 0.6 9.9 10 1 1 11 11 8 0 Leucine Rich Repeat ATP-synt_C PF00137.21 CBY22299.1 - 2.2e-11 43.9 14.0 3.1e-11 43.5 14.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit C DUF2228 PF10228.9 CBY22300.1 - 8.1e-63 212.5 0.0 1.1e-62 212.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) BSD PF03909.17 CBY22301.1 - 5.2e-16 58.4 0.1 3.4e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 CBY22301.1 - 5.4e-16 58.7 0.1 9.4e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain MotY_N PF18393.1 CBY22301.1 - 0.034 14.3 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 MotY N-terminal domain POB3_N PF17292.2 CBY22301.1 - 0.045 14.2 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 POB3-like N-terminal PH domain MFS_1 PF07690.16 CBY22302.1 - 4.9e-10 38.9 20.3 4.9e-10 38.9 20.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SRP1_TIP1 PF00660.17 CBY22302.1 - 0.02 14.9 0.1 0.5 10.5 0.1 2.5 2 0 0 2 2 2 0 Seripauperin and TIP1 family Vma12 PF11712.8 CBY22302.1 - 0.089 12.9 0.0 0.089 12.9 0.0 2.9 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YmgD PF16456.5 CBY22302.1 - 0.11 12.5 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 YmgD protein ABC2_membrane_2 PF12679.7 CBY22302.1 - 0.41 9.9 9.1 2.8 7.1 8.7 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein F-box PF00646.33 CBY22303.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CBY22303.1 - 0.0006 19.7 0.0 0.00098 19.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 CBY22304.1 - 4.1e-06 27.4 0.2 0.21 12.5 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY22304.1 - 0.0015 18.8 0.0 1.4 9.3 0.0 4.3 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain YmzC PF14157.6 CBY22304.1 - 0.024 14.7 0.0 0.083 13.0 0.0 1.8 1 0 0 1 1 1 0 YmzC-like protein VID27 PF08553.10 CBY22304.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain DUF5511 PF17630.2 CBY22304.1 - 0.071 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5511) PLAC PF08686.11 CBY22304.1 - 0.083 13.7 0.1 0.18 12.6 0.1 1.6 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain Formyl_trans_C PF02911.18 CBY22304.1 - 0.13 12.6 0.0 1.5 9.1 0.0 2.6 3 1 0 3 3 3 0 Formyl transferase, C-terminal domain Ank_2 PF12796.7 CBY22305.1 - 7.5e-140 455.9 31.9 6.9e-19 68.2 3.9 12.2 4 3 7 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 CBY22305.1 - 2.5e-116 375.5 33.1 2.8e-07 30.7 0.0 23.9 24 0 0 24 24 24 21 Ankyrin repeat Ank_4 PF13637.6 CBY22305.1 - 1.1e-115 376.6 8.5 1.2e-10 41.7 0.2 15.9 10 4 6 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY22305.1 - 4.7e-102 321.5 19.4 3.6e-05 23.8 0.0 24.6 24 0 0 24 24 24 20 Ankyrin repeat Ank_5 PF13857.6 CBY22305.1 - 2.6e-81 266.6 24.2 2.6e-07 30.8 0.0 19.5 6 4 13 20 20 20 19 Ankyrin repeats (many copies) KH_1 PF00013.29 CBY22305.1 - 2.2e-14 53.0 0.1 1.6e-13 50.2 0.5 2.3 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 CBY22305.1 - 0.61 10.0 0.0 0.61 10.0 0.0 3.2 3 0 0 3 3 3 0 KH domain NAC PF01849.18 CBY22306.1 - 1.5e-26 92.2 0.1 2.8e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 NAC domain tRNA_synthFbeta PF17759.1 CBY22307.1 - 2e-43 148.3 0.0 3.1e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CBY22307.1 - 5.3e-28 97.1 0.0 6.4e-27 93.6 0.2 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CBY22307.1 - 1.9e-27 96.1 0.0 3.4e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CBY22307.1 - 1.9e-14 53.7 0.1 3.9e-11 43.1 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.8 CBY22307.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) zf-HC5HC2H_2 PF13832.6 CBY22308.1 - 2.3e-25 88.9 6.3 2.3e-25 88.9 6.3 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBY22308.1 - 1.6e-19 69.9 4.5 1.6e-19 69.9 4.5 3.9 3 1 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CBY22308.1 - 1e-12 47.4 6.2 1e-12 47.4 6.2 3.7 4 1 0 4 4 4 1 PHD-finger PHD PF00628.29 CBY22308.1 - 7.1e-10 38.6 10.7 7.1e-10 38.6 10.7 3.4 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 CBY22308.1 - 0.0031 17.4 3.1 0.0031 17.4 3.1 3.8 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Epsilon_antitox PF08998.11 CBY22308.1 - 0.12 12.7 0.2 0.24 11.7 0.2 1.5 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Troponin PF00992.20 CBY22310.1 - 2.1e-23 83.1 43.8 1.7e-22 80.2 37.4 2.0 1 1 1 2 2 2 2 Troponin DUF2151 PF10221.9 CBY22310.1 - 0.17 10.4 14.5 0.2 10.2 14.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4778 PF16008.5 CBY22310.1 - 1.3 9.0 19.6 1.6 8.7 19.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Piwi PF02171.17 CBY22311.1 - 1e-56 192.4 0.0 1.6e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CBY22311.1 - 1.4e-09 38.7 0.0 2.8e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CBY22311.1 - 0.0017 18.0 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain FGF PF00167.18 CBY22312.1 - 0.00031 20.9 0.0 0.00066 19.8 0.0 1.6 1 1 0 1 1 1 1 Fibroblast growth factor Peptidase_M28 PF04389.17 CBY22313.1 - 4.1e-23 82.1 0.0 6.9e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CBY22313.1 - 1.7e-06 28.0 0.0 3.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CBY22313.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 TFR_dimer PF04253.15 CBY22313.1 - 0.0021 18.2 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain EGF_CA PF07645.15 CBY22314.1 - 1.1e-60 201.6 160.2 1.2e-06 28.6 9.5 10.4 9 1 0 10 10 10 10 Calcium-binding EGF domain EGF_3 PF12947.7 CBY22314.1 - 6.4e-16 58.3 130.9 0.005 17.0 3.8 12.3 10 2 0 10 10 10 10 EGF domain cEGF PF12662.7 CBY22314.1 - 9.6e-10 38.2 120.1 0.0051 16.7 5.7 12.7 10 2 0 10 10 10 7 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY22314.1 - 7.6e-07 29.3 121.5 0.2 11.9 1.0 11.8 6 3 5 12 12 12 6 Coagulation Factor Xa inhibitory site FTR PF01913.18 CBY22314.1 - 0.17 11.8 2.9 11 6.0 0.2 2.3 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase EGF PF00008.27 CBY22314.1 - 0.3 11.4 116.1 0.23 11.8 4.2 11.2 10 0 0 10 10 10 0 EGF-like domain Peptidase_C2 PF00648.21 CBY22315.1 - 1.3e-72 244.3 0.1 1.7e-72 244.0 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Tmemb_185A PF10269.9 CBY22316.1 - 5.3e-42 144.2 21.4 7.1e-42 143.8 21.4 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein EMP70 PF02990.16 CBY22316.1 - 0.72 8.5 17.0 0.68 8.5 3.4 2.6 1 1 1 2 2 2 0 Endomembrane protein 70 Amidohydro_3 PF07969.11 CBY22317.1 - 1.2e-62 212.9 0.0 1.4e-62 212.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CBY22317.1 - 1.3e-06 27.9 0.0 0.0014 18.0 0.0 3.0 3 0 0 3 3 3 3 Amidohydrolase family Sulfotransfer_2 PF03567.14 CBY22318.1 - 1.3e-34 120.2 0.1 1.9e-34 119.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family NDK PF00334.19 CBY22319.1 - 3.6e-53 179.2 0.0 4.1e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase YesK PF14150.6 CBY22320.1 - 0.36 11.0 7.1 0.18 12.0 3.7 2.2 2 0 0 2 2 2 0 YesK-like protein PDZ PF00595.24 CBY22321.1 - 3.2e-41 139.5 0.2 1.1e-12 48.1 0.0 3.2 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CBY22321.1 - 1.6e-32 111.1 2.8 3.3e-10 39.7 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CBY22321.1 - 2.4e-18 66.2 0.1 5.8e-05 23.3 0.0 3.2 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 CBY22321.1 - 0.00038 20.4 0.5 4.8 7.2 0.1 3.3 3 0 0 3 3 3 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 CBY22321.1 - 0.035 14.5 0.0 6.6 7.2 0.0 3.1 3 0 0 3 3 3 0 PDZ domain PDZ PF00595.24 CBY22322.1 - 7.2e-16 58.3 1.8 0.00038 20.8 0.1 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CBY22322.1 - 1.6e-12 47.1 1.6 0.011 15.6 0.1 4.2 4 0 0 4 4 4 3 PDZ domain Guanylate_kin PF00625.21 CBY22322.1 - 3.9e-10 39.7 0.0 7.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase WW PF00397.26 CBY22322.1 - 1.9e-08 34.2 0.1 3.6e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 WW domain PDZ_2 PF13180.6 CBY22322.1 - 0.00017 21.9 0.2 0.65 10.4 0.0 3.3 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 CBY22322.1 - 0.0042 17.0 0.1 0.54 10.3 0.0 3.4 4 0 0 4 4 4 1 Tricorn protease PDZ domain DUF99 PF01949.16 CBY22322.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 SPOC PF07744.13 CBY22323.1 - 7.3e-12 45.5 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 SPOC domain CxC7 PF18866.1 CBY22323.1 - 0.087 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases DUF3006 PF11213.8 CBY22324.1 - 0.029 14.6 0.1 16 5.8 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3006) Adhesin_Dr PF04619.12 CBY22324.1 - 0.19 11.6 0.1 3 7.8 0.0 2.5 2 1 1 3 3 3 0 Dr-family adhesin Y_phosphatase PF00102.27 CBY22326.1 - 5.6e-62 209.4 1.2 9.2e-62 208.7 1.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBY22326.1 - 0.0042 16.9 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBY22326.1 - 0.0046 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBY22326.1 - 0.022 14.8 0.1 0.09 12.9 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CBY22326.1 - 0.035 13.7 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Rhodanese PF00581.20 CBY22326.1 - 0.13 12.8 0.0 9.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Rhodanese-like domain DUF1217 PF06748.12 CBY22327.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) AAT PF03417.16 CBY22328.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase PAX PF00292.18 CBY22330.1 - 3.2e-35 120.8 0.2 5.3e-35 120.1 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CBY22330.1 - 1.5e-20 72.8 2.0 1.5e-20 72.8 2.0 2.8 4 0 0 4 4 4 1 Homeodomain Homeobox_KN PF05920.11 CBY22330.1 - 5.8e-05 22.9 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_32 PF13565.6 CBY22330.1 - 0.00087 19.9 0.2 0.019 15.6 0.0 2.8 2 1 1 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 CBY22330.1 - 0.016 15.2 0.1 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 CBY22330.1 - 0.017 14.9 0.1 0.26 11.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain PI-PLC-X PF00388.19 CBY22331.1 - 9.5e-60 200.4 0.0 1.9e-59 199.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY22331.1 - 7.8e-39 132.6 0.1 2e-38 131.3 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CBY22331.1 - 7.1e-13 48.7 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 CBY22331.1 - 1.3e-09 37.2 0.8 0.0001 21.9 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY22331.1 - 1.2e-07 32.1 0.1 4.2e-07 30.3 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY22331.1 - 6.5e-07 28.5 1.8 0.00083 18.7 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_like PF09279.11 CBY22331.1 - 1.6e-06 28.5 0.4 5.8e-06 26.7 0.4 2.0 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.6 CBY22331.1 - 4e-05 23.4 0.9 0.00014 21.7 0.5 2.1 1 1 1 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY22331.1 - 0.0001 21.6 0.5 0.0091 15.5 0.1 2.7 2 0 0 2 2 2 1 EF hand PH_12 PF16457.5 CBY22331.1 - 0.00055 20.5 3.8 0.00095 19.7 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain EF-hand_8 PF13833.6 CBY22331.1 - 0.0022 17.8 0.3 2.5 8.0 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair PH PF00169.29 CBY22331.1 - 0.0043 17.5 3.0 0.0046 17.4 0.2 2.6 3 0 0 3 3 3 1 PH domain Caleosin PF05042.13 CBY22331.1 - 0.0094 15.9 0.1 0.033 14.1 0.1 1.9 1 1 0 1 1 1 1 Caleosin related protein Ank_2 PF12796.7 CBY22332.1 - 3.4e-78 258.3 42.4 2.5e-13 50.4 0.4 6.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY22332.1 - 5e-46 154.5 32.7 1.4e-06 28.7 0.4 9.8 3 3 9 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY22332.1 - 5.3e-44 147.7 14.3 6.1e-07 29.6 1.3 8.4 5 3 2 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 CBY22332.1 - 9.3e-44 146.0 24.7 9.1e-05 22.7 0.3 11.9 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.6 CBY22332.1 - 2.3e-42 138.1 7.7 0.0042 17.5 0.0 12.2 12 0 0 12 12 12 10 Ankyrin repeat PBP PF01161.20 CBY22333.1 - 1.8e-15 57.5 0.0 2.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LRR_8 PF13855.6 CBY22334.1 - 1.2e-16 60.2 3.6 2.3e-05 24.1 0.1 3.3 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBY22334.1 - 2.7e-14 53.0 9.9 0.0001 22.6 2.8 4.1 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY22334.1 - 0.00015 21.3 4.3 0.04 13.4 0.3 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CBY22334.1 - 0.0012 19.1 12.0 5.4 8.0 0.3 6.5 5 2 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 CBY22334.1 - 0.022 14.8 3.7 15 5.9 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Troponin PF00992.20 CBY22335.1 - 1.7e-25 89.8 16.0 1.9e-25 89.7 16.0 1.0 1 0 0 1 1 1 1 Troponin DUF3584 PF12128.8 CBY22335.1 - 0.0031 15.1 6.5 0.0034 15.0 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) BssS PF13991.6 CBY22335.1 - 0.044 13.9 0.1 0.07 13.2 0.1 1.5 1 0 0 1 1 1 0 BssS protein family SLATT_fungal PF18142.1 CBY22335.1 - 0.097 12.7 1.0 0.15 12.0 1.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain SWI-SNF_Ssr4 PF08549.10 CBY22335.1 - 0.12 11.0 4.2 0.13 10.9 4.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) XhlA PF10779.9 CBY22335.1 - 0.71 10.1 4.3 9.4 6.5 1.5 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Med9 PF07544.13 CBY22335.1 - 1.4 9.1 8.3 0.35 11.0 1.2 2.8 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Jnk-SapK_ap_N PF09744.9 CBY22335.1 - 1.7 8.8 12.8 2.4 8.4 12.8 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3810 PF12725.7 CBY22335.1 - 3.4 6.9 5.1 3 7.1 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) BTB PF00651.31 CBY22336.1 - 6.2e-16 58.6 0.0 1.3e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 CBY22336.1 - 9.1e-13 48.0 13.0 8.1e-08 32.4 0.3 4.0 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY22336.1 - 1.2e-10 41.2 18.3 9.3e-05 22.7 1.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY22336.1 - 8.9e-08 32.3 16.1 0.002 18.8 0.7 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY22336.1 - 0.00014 21.8 15.9 0.00051 20.0 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CBY22336.1 - 0.07 13.6 11.5 0.65 10.5 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CBY22336.1 - 0.29 11.3 3.6 8.3 6.6 1.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 CBY22336.1 - 0.39 11.1 10.6 0.85 10.0 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY22336.1 - 0.63 10.4 8.6 8.3 6.8 0.2 3.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CBY22336.1 - 1.7 9.2 6.5 6.7 7.2 0.1 3.5 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_recom PF13408.6 CBY22336.1 - 2.3 8.8 4.9 31 5.2 0.2 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 CBY22336.1 - 9.7 6.6 13.8 3.4 8.1 0.2 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3 PF13878.6 CBY22336.1 - 9.8 6.1 10.1 0.6 10.0 1.9 3.0 3 0 0 3 3 2 0 zinc-finger of acetyl-transferase ESCO Tubulin PF00091.25 CBY22337.1 - 1.2e-47 162.7 0.0 1.8e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY22337.1 - 2.3e-15 56.9 0.0 3.8e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain DDE_Tnp_1 PF01609.21 CBY22337.1 - 0.1 12.2 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Transposase DDE domain Astacin PF01400.24 CBY22338.1 - 1.7e-21 76.7 0.0 2e-19 70.0 0.0 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_3 PF12947.7 CBY22338.1 - 1.7e-10 40.9 32.0 2e-06 27.9 9.5 5.8 5 1 0 5 5 5 2 EGF domain EGF_CA PF07645.15 CBY22338.1 - 3.7e-06 27.0 13.2 3.7e-06 27.0 13.2 4.4 5 1 0 5 5 5 1 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 CBY22338.1 - 0.0026 17.8 26.8 0.024 14.7 5.2 3.9 3 0 0 3 3 3 2 MSP1 EGF domain 1 EGF PF00008.27 CBY22338.1 - 0.0037 17.5 35.0 0.0086 16.4 7.3 4.4 4 0 0 4 4 4 2 EGF-like domain Ldl_recept_a PF00057.18 CBY22338.1 - 0.015 15.5 0.1 0.015 15.5 0.1 5.4 6 0 0 6 6 6 0 Low-density lipoprotein receptor domain class A hEGF PF12661.7 CBY22338.1 - 0.019 15.6 4.9 0.019 15.6 4.9 6.0 6 0 0 6 6 6 0 Human growth factor-like EGF cEGF PF12662.7 CBY22338.1 - 0.024 14.6 2.2 0.024 14.6 2.2 4.0 4 0 0 4 4 4 0 Complement Clr-like EGF-like DUF4064 PF13273.6 CBY22339.1 - 0.033 14.5 3.8 3.7 7.9 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4231 PF14015.6 CBY22339.1 - 0.16 12.4 7.4 1.3 9.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SecG PF03840.14 CBY22339.1 - 0.17 12.0 0.2 0.17 12.0 0.2 2.9 2 1 1 3 3 3 0 Preprotein translocase SecG subunit DUF2157 PF09925.9 CBY22339.1 - 0.19 11.5 6.2 0.42 10.4 4.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) SUR7 PF06687.12 CBY22339.1 - 5.6 6.5 13.1 0.34 10.5 0.1 2.6 2 1 1 3 3 3 0 SUR7/PalI family Jagunal PF07086.12 CBY22340.1 - 0.89 9.6 6.9 1.2 9.2 6.9 1.1 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis CDO_I PF05995.12 CBY22341.1 - 6.8e-42 142.6 0.0 8.5e-42 142.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CBY22341.1 - 0.0026 17.2 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO zf-C2H2 PF00096.26 CBY22342.1 - 4.2e-07 30.1 9.7 0.0032 17.8 3.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY22342.1 - 2e-05 24.8 5.5 0.019 15.4 0.5 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY22342.1 - 0.014 16.2 0.2 0.014 16.2 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY22342.1 - 0.096 13.0 3.2 3.4 8.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY22342.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double domain RT_RNaseH_2 PF17919.1 CBY22343.1 - 1.6e-10 40.9 0.0 4.2e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY22343.1 - 3.6e-08 33.6 0.0 1.4e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY22343.1 - 7.6e-08 32.1 0.0 2.2e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CBY22343.1 - 0.0015 19.2 0.2 0.0056 17.3 0.2 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY22343.1 - 0.0031 18.0 0.2 0.011 16.2 0.2 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 CBY22343.1 - 0.0096 16.0 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain HOCHOB PF17943.1 CBY22345.1 - 0.015 16.0 1.9 0.84 10.4 0.1 3.2 3 0 0 3 3 3 0 Homeobox-cysteine loop-homeobox GCP_C_terminal PF04130.13 CBY22346.1 - 3.6e-52 177.7 8.0 4.3e-52 177.5 8.0 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF2935 PF11155.8 CBY22346.1 - 0.043 14.1 0.5 0.043 14.1 0.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Vps54 PF07928.12 CBY22346.1 - 0.079 13.4 0.9 0.12 12.8 0.9 1.3 1 0 0 1 1 1 0 Vps54-like protein DUF999 PF06198.11 CBY22346.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF999) GCP_N_terminal PF17681.1 CBY22347.1 - 7.6e-16 58.6 0.0 1e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CBY22347.1 - 8.6e-16 58.3 0.6 1.3e-15 57.6 0.2 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBY22348.1 - 1.7e-07 31.1 0.1 3.2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Rotamase PF00639.21 CBY22349.1 - 5.6e-22 78.5 0.0 7.5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CBY22349.1 - 4.5e-20 72.3 0.0 5.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CBY22349.1 - 7.7e-13 48.3 0.5 1.3e-12 47.5 0.5 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 CBY22349.1 - 0.00023 22.0 0.0 0.00036 21.3 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain SH3_9 PF14604.6 CBY22350.1 - 1.2e-14 53.9 0.1 2.1e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY22350.1 - 1.5e-13 50.1 0.1 5.3e-13 48.4 0.1 2.0 2 0 0 2 2 2 1 SH3 domain FCH PF00611.23 CBY22350.1 - 7.8e-13 48.5 0.3 7.8e-13 48.5 0.3 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 CBY22350.1 - 2.7e-07 30.2 0.0 6.9e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF763 PF05559.11 CBY22350.1 - 2.5 7.2 6.8 0.62 9.2 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF763) zf-RING_2 PF13639.6 CBY22351.1 - 3.4e-14 52.9 6.5 6.6e-14 52.0 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY22351.1 - 3.8e-12 45.8 6.1 7.7e-12 44.9 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY22351.1 - 8e-11 41.5 3.9 1.8e-10 40.4 3.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CBY22351.1 - 2.9e-08 33.4 4.8 5.5e-08 32.6 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY22351.1 - 7.2e-08 32.6 7.4 7.2e-08 32.6 7.4 2.3 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBY22351.1 - 1.2e-07 31.6 3.2 2.4e-07 30.6 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY22351.1 - 9.6e-07 28.6 3.2 1.5e-06 27.9 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY22351.1 - 2.3e-06 27.5 3.4 4e-06 26.7 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CBY22351.1 - 0.0021 17.6 3.6 0.004 16.8 3.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBY22351.1 - 0.0024 17.7 4.1 0.0051 16.6 4.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CBY22351.1 - 0.0031 17.5 3.5 0.0031 17.5 3.5 2.0 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 CBY22351.1 - 0.014 15.7 3.3 0.036 14.4 3.3 1.8 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 CBY22351.1 - 0.017 15.3 4.3 0.055 13.6 4.3 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 CBY22351.1 - 0.021 15.1 2.0 0.032 14.5 1.0 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3H2C3 PF17122.5 CBY22351.1 - 0.053 13.6 4.6 0.13 12.3 4.6 1.7 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 CBY22351.1 - 0.068 13.3 3.2 0.19 11.9 3.2 1.8 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 CBY22351.1 - 0.41 10.6 3.6 0.85 9.6 3.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 CBY22351.1 - 0.52 10.2 3.0 1.2 9.0 3.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TFIIA PF03153.13 CBY22351.1 - 0.56 10.1 10.7 0.76 9.7 10.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CBY22351.1 - 1.5 8.7 23.6 2.3 8.1 23.6 1.3 1 0 0 1 1 1 0 SPX domain DUF719 PF05334.13 CBY22351.1 - 4.8 7.3 7.1 0.28 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF719) YugN PF08868.10 CBY22353.1 - 0.089 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 YugN-like family Collagen PF01391.18 CBY22354.1 - 1.7e-40 136.5 172.1 1.1e-08 34.7 21.5 6.3 1 1 5 6 6 6 6 Collagen triple helix repeat (20 copies) C1q PF00386.21 CBY22354.1 - 5.7e-08 33.0 0.1 8.7e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 C1q domain PPC PF04151.15 CBY22354.1 - 0.031 15.4 0.3 0.058 14.5 0.3 1.3 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain AAA_12 PF13087.6 CBY22355.1 - 5.6e-42 143.6 0.0 1e-41 142.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBY22355.1 - 8.3e-42 143.8 0.5 5.3e-22 78.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CBY22355.1 - 1.9e-17 63.6 0.2 2.8e-16 59.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY22355.1 - 8.4e-11 42.4 0.0 3.1e-10 40.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBY22355.1 - 2.4e-10 40.6 0.1 0.0057 16.4 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CBY22355.1 - 1.3e-05 25.2 2.0 2.9e-05 24.0 0.4 2.4 2 1 0 2 2 2 1 Helicase AAA_22 PF13401.6 CBY22355.1 - 3.1e-05 24.3 0.1 0.00023 21.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY22355.1 - 5e-05 23.8 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CBY22355.1 - 5.2e-05 23.7 0.0 0.00016 22.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 CBY22355.1 - 0.00027 20.7 0.0 0.00063 19.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 CBY22355.1 - 0.00065 19.0 0.0 0.023 14.0 0.0 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CBY22355.1 - 0.0011 18.5 0.0 0.051 13.0 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein RuvB_N PF05496.12 CBY22355.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CBY22355.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.15 CBY22355.1 - 0.0021 18.1 0.0 0.0047 17.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CBY22355.1 - 0.0055 15.8 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.13 CBY22355.1 - 0.0071 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 CBY22355.1 - 0.0093 15.9 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain MeaB PF03308.16 CBY22355.1 - 0.015 14.3 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 CBY22355.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBY22355.1 - 0.016 15.2 0.0 0.053 13.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBY22355.1 - 0.02 15.1 0.1 0.052 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY22355.1 - 0.031 14.7 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase GARS_N PF02844.15 CBY22355.1 - 0.032 15.0 0.0 0.17 12.7 0.0 2.1 2 0 0 2 2 1 0 Phosphoribosylglycinamide synthetase, N domain RsgA_GTPase PF03193.16 CBY22355.1 - 0.037 13.9 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 CBY22355.1 - 0.042 13.9 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 CBY22355.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain DnaB_C PF03796.15 CBY22355.1 - 0.054 12.8 0.2 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MMR_HSR1 PF01926.23 CBY22355.1 - 0.059 13.5 0.1 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CBY22355.1 - 0.065 13.8 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CBY22355.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CBY22355.1 - 0.085 13.4 1.2 1.9 9.1 0.0 2.8 3 1 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.9 CBY22355.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Flavi_DEAD PF07652.14 CBY22355.1 - 0.12 12.4 0.2 0.5 10.3 0.1 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_7 PF12775.7 CBY22355.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CBY22355.1 - 0.14 11.3 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 CBY22355.1 - 0.24 11.3 2.3 0.61 10.0 0.1 2.7 3 1 1 4 4 3 0 NTPase XAF1_C PF18608.1 CBY22356.1 - 0.0015 18.1 0.4 0.0033 17.0 0.4 1.6 1 0 0 1 1 1 1 XIAP-associated factor 1 C-terminal domain zf_UBZ PF18439.1 CBY22356.1 - 0.017 14.7 0.2 0.034 13.7 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DUF4381 PF14316.6 CBY22357.1 - 0.0039 17.5 0.0 0.0057 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) MFS_1 PF07690.16 CBY22357.1 - 0.012 14.6 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF4083 PF13314.6 CBY22357.1 - 0.012 15.6 0.4 0.029 14.3 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PAP_PilO PF06864.12 CBY22357.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) RCR PF12273.8 CBY22357.1 - 0.14 12.8 0.0 0.23 12.1 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red YajC PF02699.15 CBY22357.1 - 0.95 9.4 2.6 0.88 9.5 0.4 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit Antimicrobial_2 PF08023.12 CBY22357.1 - 1.3 9.6 3.6 36 5.0 0.0 3.4 4 1 1 5 5 5 0 Frog antimicrobial peptide CSTF2_hinge PF14327.6 CBY22358.1 - 0.017 15.6 4.5 0.11 13.0 0.5 3.3 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Coatomer_E PF04733.14 CBY22359.1 - 2.4e-83 279.9 2.7 2.7e-83 279.8 2.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 CBY22359.1 - 0.00055 20.4 6.1 1.5 9.4 0.6 4.0 3 2 2 5 5 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBY22359.1 - 0.002 17.8 0.6 1.6 8.4 0.0 3.8 1 1 2 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 CBY22359.1 - 0.0031 17.4 0.3 2.3 8.4 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY22359.1 - 0.0041 17.1 1.8 1.3 9.3 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY22359.1 - 0.02 15.1 0.5 9.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 CBY22359.1 - 0.042 13.9 1.3 0.55 10.3 0.2 2.6 2 1 1 3 3 3 0 Putative TPR-like repeat TPR_6 PF13174.6 CBY22359.1 - 0.36 11.6 1.5 62 4.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat APG5 PF04106.12 CBY22360.1 - 1.1e-20 74.3 0.8 6.9e-20 71.6 0.3 2.4 2 1 0 2 2 2 1 Autophagy protein Apg5 ubiquitin PF00240.23 CBY22360.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family Cpn60_TCP1 PF00118.24 CBY22361.1 - 3.1e-148 494.5 17.6 3.6e-148 494.2 17.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GlcNAc-1_reg PF18440.1 CBY22361.1 - 0.015 15.5 2.5 0.27 11.5 0.0 3.0 3 0 0 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF643 PF04867.12 CBY22361.1 - 0.085 13.5 1.4 4.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF643) DUF4201 PF13870.6 CBY22362.1 - 2.1e-37 128.6 33.4 2.1e-37 128.6 33.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DivIC PF04977.15 CBY22362.1 - 0.17 11.7 0.2 0.17 11.7 0.2 4.7 4 1 1 5 5 5 0 Septum formation initiator PRKG1_interact PF15898.5 CBY22363.1 - 0.0068 17.3 13.3 0.0068 17.3 13.3 3.8 3 1 1 4 4 4 2 cGMP-dependent protein kinase interacting domain DUF4174 PF13778.6 CBY22363.1 - 0.081 13.4 6.9 0.37 11.3 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4174) Rootletin PF15035.6 CBY22363.1 - 4 7.4 43.0 10 6.1 14.0 4.1 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion CTP_transf_like PF01467.26 CBY22364.1 - 0.22 11.7 1.6 0.55 10.4 0.5 2.1 2 0 0 2 2 2 0 Cytidylyltransferase-like Tox-SHH PF15652.6 CBY22364.1 - 1.9 9.5 7.2 2.2 9.3 0.2 3.5 3 1 0 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature Neur_chan_LBD PF02931.23 CBY22365.1 - 1.4e-50 171.7 2.8 3.1e-45 154.3 0.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY22365.1 - 4.3e-41 141.6 5.6 5.6e-41 141.2 5.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region UQ_con PF00179.26 CBY22366.1 - 2.3e-24 85.6 0.0 2.5e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CBY22366.1 - 0.005 16.7 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 CBY22366.1 - 0.019 15.2 0.0 0.048 13.9 0.0 1.7 1 1 1 2 2 2 0 RWD domain SMC_N PF02463.19 CBY22367.1 - 5.4e-69 232.0 22.1 1.2e-68 230.8 22.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBY22367.1 - 2.6e-17 63.2 0.9 1.5e-16 60.7 0.0 2.8 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBY22367.1 - 8.6e-11 42.2 4.2 2.7e-05 24.1 0.0 3.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBY22367.1 - 8.1e-10 39.5 10.1 8.1e-10 39.5 10.1 6.9 2 2 4 6 6 3 1 AAA domain AAA_29 PF13555.6 CBY22367.1 - 9.9e-05 22.0 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 CBY22367.1 - 0.0022 16.7 12.9 0.0022 16.7 12.9 5.7 3 2 4 7 7 7 2 AAA domain HAMP PF00672.25 CBY22367.1 - 0.005 17.2 0.3 0.063 13.7 0.1 3.0 2 0 0 2 2 2 1 HAMP domain Cep57_CLD_2 PF14197.6 CBY22367.1 - 0.0065 16.5 9.2 0.0065 16.5 9.2 7.9 9 1 0 9 9 7 1 Centrosome localisation domain of PPC89 Metal_resist PF13801.6 CBY22367.1 - 0.016 15.4 0.0 0.016 15.4 0.0 4.1 5 2 2 7 7 4 0 Heavy-metal resistance FlaC_arch PF05377.11 CBY22367.1 - 0.082 13.3 0.1 0.082 13.3 0.1 10.7 7 4 2 11 11 11 0 Flagella accessory protein C (FlaC) Phage_tail_APC PF16778.5 CBY22367.1 - 0.094 12.6 0.1 0.73 9.8 0.0 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone protein ABC_tran PF00005.27 CBY22367.1 - 0.2 12.1 0.0 0.2 12.1 0.0 6.3 4 2 0 4 4 2 0 ABC transporter Fez1 PF06818.15 CBY22367.1 - 3.4 8.1 108.2 0.033 14.6 10.7 6.4 2 2 4 6 6 6 0 Fez1 AAA_22 PF13401.6 CBY22367.1 - 4 7.7 9.9 11 6.3 0.0 4.4 4 1 0 4 4 4 0 AAA domain BAG6 PF12057.8 CBY22368.1 - 0.00026 20.6 0.2 0.0019 17.9 0.1 2.1 2 0 0 2 2 2 1 BCL2-associated athanogene 6 DUF4119 PF13494.6 CBY22368.1 - 0.1 12.8 0.3 2.5 8.3 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Acyltransferase PF01553.21 CBY22369.1 - 8e-07 28.7 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 CBY22369.1 - 4.4e-06 25.8 0.0 6.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase zf-U1 PF06220.12 CBY22370.1 - 3.1e-07 30.0 1.1 5.7e-07 29.2 1.1 1.5 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 CBY22370.1 - 3.3e-07 30.3 4.4 3.3e-07 30.3 4.4 2.0 2 0 0 2 2 2 1 WW domain zf-DBF PF07535.12 CBY22370.1 - 0.22 11.7 2.5 0.45 10.7 2.5 1.5 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_jaz PF12171.8 CBY22370.1 - 7.4 7.0 8.4 29 5.1 8.4 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 CBY22372.1 - 1.5e-46 157.0 27.6 1.1e-24 87.0 3.5 2.6 3 0 0 3 3 3 2 CHORD CS PF04969.16 CBY22372.1 - 4.5e-08 34.0 0.1 9.5e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 CS domain BTK PF00779.19 CBY22372.1 - 0.94 9.4 18.1 1.6 8.6 4.3 4.2 4 1 0 4 4 4 0 BTK motif RRM_1 PF00076.22 CBY22373.1 - 4.5e-20 71.2 0.0 1.2e-15 57.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CBY22373.1 - 0.00091 19.2 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.11 CBY22373.1 - 0.008 16.2 0.1 0.074 13.1 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 CBY22373.1 - 0.045 13.9 0.1 1.5 9.0 0.0 2.9 1 1 1 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 CBY22373.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DIRP PF06584.13 CBY22373.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 DIRP DUF1866 PF08952.11 CBY22373.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) PRP38_assoc PF12871.7 CBY22373.1 - 0.28 11.8 14.8 0.55 10.9 14.8 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RRM_1 PF00076.22 CBY22374.1 - 1.8e-27 94.9 0.0 8e-15 54.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBY22374.1 - 5.9e-06 26.3 0.7 0.0011 19.0 0.1 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_occluded PF16842.5 CBY22374.1 - 3.5e-05 23.6 0.0 0.17 11.8 0.0 2.4 2 1 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBY22374.1 - 0.00025 21.0 0.2 0.0017 18.3 0.1 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBY22374.1 - 0.00047 19.7 0.0 0.1 12.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CBY22374.1 - 0.0053 16.4 0.0 0.031 13.9 0.0 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated DbpA PF03880.15 CBY22374.1 - 0.007 16.3 0.1 1.4 9.0 0.0 2.5 2 1 0 2 2 2 1 DbpA RNA binding domain PRP38_assoc PF12871.7 CBY22374.1 - 0.76 10.4 52.7 0.11 13.1 31.6 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Arm-DNA-bind_4 PF14657.6 CBY22374.1 - 1.4 8.8 3.8 40 4.1 0.0 2.8 2 0 0 2 2 2 0 Arm DNA-binding domain Connexin PF00029.19 CBY22375.1 - 2.4e-46 158.4 5.8 2.9e-46 158.2 5.8 1.0 1 0 0 1 1 1 1 Connexin Pkinase PF00069.25 CBY22376.1 - 1.8e-37 129.1 0.0 3.6e-37 128.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22376.1 - 4.5e-17 62.2 0.0 4.3e-14 52.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBY22376.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY22376.1 - 0.023 14.3 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CBY22376.1 - 0.066 12.0 0.0 0.26 10.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase dsrm PF00035.26 CBY22377.1 - 0.015 16.0 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif Botulinum_HA-17 PF05588.11 CBY22377.1 - 0.06 13.5 0.0 0.083 13.0 0.0 1.1 1 0 0 1 1 1 0 Clostridium botulinum HA-17 domain Ski_Sno PF02437.17 CBY22379.1 - 7.4e-39 131.8 0.1 1.2e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 SKI/SNO/DAC family zf-C3HC4_3 PF13920.6 CBY22380.1 - 1.3e-08 34.6 4.4 3.1e-08 33.4 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY22380.1 - 0.00038 20.3 3.7 0.0026 17.6 3.7 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TLP-20 PF06088.11 CBY22380.1 - 0.0023 17.9 4.1 0.0027 17.6 4.1 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Tli4_N PF18443.1 CBY22380.1 - 0.052 13.9 1.5 0.093 13.1 1.5 1.4 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain zf-RING_2 PF13639.6 CBY22380.1 - 0.083 13.2 1.2 0.083 13.2 1.2 2.6 3 0 0 3 3 3 0 Ring finger domain SURF2 PF05477.11 CBY22381.1 - 0.24 11.0 12.9 0.35 10.5 12.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4462 PF14692.6 CBY22382.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) FXa_inhibition PF14670.6 CBY22383.1 - 2.5e-07 30.9 11.5 2.5e-07 30.9 11.5 3.1 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site Sushi PF00084.20 CBY22383.1 - 0.00028 21.4 2.0 0.00028 21.4 2.0 2.1 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) PspB PF06667.12 CBY22384.1 - 0.25 11.4 0.0 0.25 11.4 0.0 3.0 3 0 0 3 3 3 0 Phage shock protein B Sld7_C PF18596.1 CBY22385.1 - 0.02 15.0 0.1 0.053 13.6 0.1 1.7 1 0 0 1 1 1 0 Sld7 C-terminal domain COPIIcoated_ERV PF07970.12 CBY22386.1 - 1.6e-25 90.3 0.2 1e-24 87.6 0.1 2.2 1 1 1 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBY22386.1 - 8.9e-24 83.7 0.2 1.7e-23 82.7 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Astacin PF01400.24 CBY22388.1 - 8.4e-20 71.2 0.0 8.4e-20 71.2 0.0 2.9 2 2 0 2 2 2 1 Astacin (Peptidase family M12A) Mucin PF01456.17 CBY22388.1 - 0.0059 16.6 21.2 0.0098 15.9 21.2 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Ldl_recept_a PF00057.18 CBY22388.1 - 0.025 14.8 2.8 0.053 13.8 2.8 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A SSP160 PF06933.11 CBY22388.1 - 0.59 8.3 20.3 0.83 7.8 20.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 CBY22388.1 - 1.2 9.1 19.3 2.5 8.1 19.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.11 CBY22388.1 - 1.7 6.6 5.3 2.5 6.1 5.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 CBY22388.1 - 4.8 5.2 9.1 7 4.6 9.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF5605 PF18310.1 CBY22389.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) cNMP_binding PF00027.29 CBY22392.1 - 2.4e-15 56.4 0.0 4.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CBY22392.1 - 0.058 13.4 5.4 0.11 12.5 4.4 2.0 1 1 1 2 2 2 0 Ion channel DUF2089 PF09862.9 CBY22392.1 - 0.11 12.6 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Toxin_R_bind_C PF07951.12 CBY22392.1 - 0.17 11.5 0.5 0.44 10.2 0.2 1.7 1 1 0 2 2 2 0 Clostridium neurotoxin, C-terminal receptor binding ATP-gua_Ptrans PF00217.19 CBY22393.1 - 2.4e-58 197.1 0.0 3.1e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY22393.1 - 1.7e-24 86.0 0.0 2.7e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain UPF0240 PF06784.11 CBY22393.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) RRM_1 PF00076.22 CBY22395.1 - 1.3e-20 72.9 0.0 1.9e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY22395.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBY22395.1 - 0.059 13.4 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBY22395.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mpv17_PMP22 PF04117.12 CBY22396.1 - 0.048 13.9 0.3 0.098 12.9 0.3 1.5 1 0 0 1 1 1 0 Mpv17 / PMP22 family TRAPPC-Trs85 PF12739.7 CBY22397.1 - 1.2e-17 64.0 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF11 PF01345.18 CBY22397.1 - 0.031 14.6 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF11 Ank_4 PF13637.6 CBY22398.1 - 2.2e-12 47.2 0.5 0.0018 18.8 0.0 6.2 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY22398.1 - 3.1e-11 43.7 2.2 4.9e-05 23.8 0.0 5.5 3 2 3 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.30 CBY22398.1 - 6.9e-08 32.6 1.0 0.65 10.6 0.0 6.1 6 1 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 CBY22398.1 - 1.7e-06 27.9 0.7 11 6.9 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 CBY22398.1 - 1.6e-05 25.1 1.1 11 6.5 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Nckap1 PF09735.9 CBY22399.1 - 5.6e-259 862.5 29.1 6.3e-259 862.3 29.1 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DAN PF03045.15 CBY22401.1 - 0.56 10.3 6.8 0.24 11.5 3.6 1.9 1 1 1 2 2 2 0 DAN domain VWD PF00094.25 CBY22402.1 - 1.5e-26 93.5 2.8 1.9e-21 77.0 2.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 CBY22402.1 - 8.9e-26 90.1 62.6 8e-14 51.8 11.5 5.8 5 1 1 6 6 6 3 C8 domain TIL PF01826.17 CBY22402.1 - 0.00021 21.4 21.1 0.001 19.2 9.1 9.5 9 1 1 10 10 10 3 Trypsin Inhibitor like cysteine rich domain Sushi PF00084.20 CBY22403.1 - 6.5e-09 36.3 11.0 3.4e-05 24.4 1.1 3.7 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) ATG_C PF09333.11 CBY22404.1 - 4.2e-20 71.9 0.1 1.1e-19 70.6 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 CBY22404.1 - 1.2e-16 60.8 0.0 1.3e-15 57.5 0.0 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CBY22404.1 - 5.9e-08 32.7 0.0 1.9e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CBY22404.1 - 0.0015 18.4 1.0 0.2 11.4 0.0 3.0 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal ATG2_CAD PF13329.6 CBY22404.1 - 0.025 14.3 0.1 0.1 12.3 0.1 2.1 1 1 0 1 1 1 0 Autophagy-related protein 2 CAD motif Acyl_transf_3 PF01757.22 CBY22406.1 - 2.7e-13 49.7 38.5 2.7e-13 49.7 38.5 1.8 2 0 0 2 2 2 1 Acyltransferase family DUF3618 PF12277.8 CBY22408.1 - 0.055 13.7 1.8 0.19 12.0 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) Pox_A_type_inc PF04508.12 CBY22408.1 - 0.69 9.9 14.4 13 5.8 0.0 6.2 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat GAS PF13851.6 CBY22408.1 - 4.4 6.6 105.3 0.54 9.6 15.6 6.6 1 1 5 6 6 6 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 CBY22408.1 - 4.7 5.6 8.0 7.4 5.0 8.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Band_7 PF01145.25 CBY22409.1 - 2.8e-26 92.6 0.3 4e-26 92.1 0.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 CBY22409.1 - 0.024 14.8 2.0 0.043 14.0 2.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 F-box PF00646.33 CBY22410.1 - 0.0019 18.0 0.1 0.0049 16.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain IBR PF01485.21 CBY22410.1 - 0.015 15.5 7.8 0.035 14.3 7.8 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain SPATIAL PF15256.6 CBY22410.1 - 0.045 14.1 0.8 0.045 14.1 0.8 1.8 1 1 0 1 1 1 0 SPATIAL Trypsin PF00089.26 CBY22411.1 - 1.5e-42 145.9 0.4 2.3e-42 145.3 0.4 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY22411.1 - 7.1e-08 33.5 0.1 1.1e-07 32.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Whib PF02467.16 CBY22411.1 - 0.072 13.7 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 Transcription factor WhiB EGF_3 PF12947.7 CBY22412.1 - 0.0012 18.9 11.9 0.0012 18.9 11.9 9.1 8 1 0 8 8 8 1 EGF domain DUF4077 PF13295.6 CBY22413.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4077) Sulfotransfer_3 PF13469.6 CBY22414.1 - 0.00038 20.9 0.0 0.0058 17.0 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY22414.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase domain DUF3522 PF12036.8 CBY22415.1 - 1.2e-60 205.0 13.2 1.7e-60 204.5 13.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) p450 PF00067.22 CBY22416.1 - 2.3e-48 165.1 0.1 3.1e-48 164.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 CBY22418.1 - 1.1e-11 44.6 2.4 2.3e-11 43.6 0.5 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22418.1 - 2.9e-06 26.8 0.0 5.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Spb1_C PF07780.12 CBY22418.1 - 0.02 14.5 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Spb1 C-terminal domain STAT_bind PF02864.15 CBY22419.1 - 0.41 11.2 2.0 0.63 10.6 0.3 2.1 3 0 0 3 3 3 0 STAT protein, DNA binding domain Lipocalin_2 PF08212.12 CBY22422.1 - 1.2e-19 70.6 0.2 1.6e-19 70.3 0.2 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY22422.1 - 2.1e-08 34.5 0.0 3.3e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 CBY22422.1 - 0.0051 16.7 0.8 0.011 15.6 0.2 1.8 2 1 0 2 2 2 1 Triabin Glutaredoxin PF00462.24 CBY22422.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Kringle PF00051.18 CBY22423.1 - 2.6e-06 27.6 1.4 2.6e-06 27.6 1.4 4.2 3 1 0 3 3 3 1 Kringle domain HMG_box_5 PF14887.6 CBY22424.1 - 0.016 15.2 0.3 3 7.9 0.1 2.9 3 0 0 3 3 3 0 HMG (high mobility group) box 5 Zona_pellucida PF00100.23 CBY22425.1 - 1e-12 48.4 0.2 1.1e-12 48.3 0.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Crystall PF00030.19 CBY22426.1 - 2.5e-12 46.8 0.1 9.5e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin ADK PF00406.22 CBY22428.1 - 1.2e-25 90.4 1.1 2.5e-11 43.9 0.0 5.6 5 0 0 5 5 5 2 Adenylate kinase AAA_17 PF13207.6 CBY22428.1 - 3.6e-19 69.5 1.7 0.0002 21.8 0.0 5.8 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.6 CBY22428.1 - 1.9e-15 57.6 1.4 0.00029 21.4 0.0 5.0 3 2 0 3 3 3 3 AAA domain AAA_33 PF13671.6 CBY22428.1 - 7.2e-09 35.9 1.3 0.014 15.5 0.0 4.7 4 1 0 4 4 3 2 AAA domain AAA_24 PF13479.6 CBY22428.1 - 1.7e-08 34.4 0.3 0.13 12.0 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.6 CBY22428.1 - 2.1e-08 34.6 1.4 0.18 12.0 0.1 4.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CBY22428.1 - 1.4e-07 31.8 0.0 0.33 11.2 0.0 3.8 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.20 CBY22428.1 - 7.5e-07 28.6 0.1 0.28 10.3 0.0 4.3 4 0 0 4 4 4 1 G-protein alpha subunit YHS PF04945.13 CBY22428.1 - 2.3e-06 27.6 1.2 0.087 12.9 0.1 4.3 4 0 0 4 4 4 1 YHS domain KTI12 PF08433.10 CBY22428.1 - 2.4e-06 27.2 0.8 0.0051 16.3 0.0 3.5 3 0 0 3 3 3 2 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 CBY22428.1 - 5.4e-06 26.5 0.0 0.38 10.8 0.0 4.2 4 0 0 4 4 3 1 50S ribosome-binding GTPase AAA PF00004.29 CBY22428.1 - 8.6e-06 26.2 0.6 0.061 13.7 0.1 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CBY22428.1 - 3.9e-05 24.2 0.1 2.5 8.6 0.0 3.9 3 0 0 3 3 3 1 ABC transporter Ploopntkinase3 PF18751.1 CBY22428.1 - 7.4e-05 22.7 0.0 1.3 8.9 0.0 3.3 3 0 0 3 3 3 2 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 CBY22428.1 - 0.00013 21.7 0.0 25 4.7 0.0 4.7 4 0 0 4 4 4 0 P-loop containing region of AAA domain FAP206 PF12018.8 CBY22428.1 - 0.00014 21.4 0.6 2.9 7.3 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function AAA_14 PF13173.6 CBY22428.1 - 0.00029 20.9 0.1 3.6 7.6 0.0 3.9 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CBY22428.1 - 0.00029 20.2 0.0 2.2 7.5 0.0 4.3 4 0 0 4 4 4 1 Zeta toxin RNA_helicase PF00910.22 CBY22428.1 - 0.00043 20.6 0.1 4.5 7.7 0.0 3.9 3 0 0 3 3 3 1 RNA helicase SKI PF01202.22 CBY22428.1 - 0.001 19.2 0.2 17 5.5 0.0 3.7 3 0 0 3 3 3 0 Shikimate kinase AAA_16 PF13191.6 CBY22428.1 - 0.0014 19.0 0.0 22 5.4 0.0 4.4 4 0 0 4 4 4 0 AAA ATPase domain Hydin_ADK PF17213.3 CBY22428.1 - 0.0015 18.9 3.0 0.14 12.4 0.1 3.1 3 0 0 3 3 2 1 Hydin Adenylate kinase-like domain TsaE PF02367.17 CBY22428.1 - 0.0025 17.8 0.0 1.3 9.0 0.0 2.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 CBY22428.1 - 0.0026 17.7 0.3 1.2 9.0 0.1 3.2 3 0 0 3 3 3 1 NTPase dNK PF01712.19 CBY22428.1 - 0.0028 17.5 0.6 11 5.8 0.1 3.8 3 0 0 3 3 3 0 Deoxynucleoside kinase PRK PF00485.18 CBY22428.1 - 0.0083 15.9 0.2 6 6.6 0.1 3.2 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 CBY22428.1 - 0.01 14.8 0.0 2.5 7.0 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cytidylate_kin PF02224.18 CBY22428.1 - 0.017 14.8 0.0 3.4 7.4 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase T2SSE PF00437.20 CBY22428.1 - 0.02 13.9 0.0 0.24 10.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.18 CBY22428.1 - 0.025 14.1 0.1 19 4.7 0.0 3.9 4 0 0 4 4 4 0 Ferrous iron transport protein B NACHT PF05729.12 CBY22428.1 - 0.039 13.9 0.5 8.1 6.3 0.0 3.2 3 0 0 3 3 3 0 NACHT domain GTP_EFTU PF00009.27 CBY22428.1 - 0.049 13.2 0.0 13 5.3 0.0 3.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain cobW PF02492.19 CBY22428.1 - 0.063 12.9 0.7 19 4.8 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 CBY22428.1 - 0.08 12.5 0.0 9.2 5.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 CBY22428.1 - 0.087 12.2 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CBY22428.1 - 0.091 11.9 0.0 5 6.2 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain Rad17 PF03215.15 CBY22428.1 - 0.11 12.4 0.2 21 5.0 0.0 3.2 3 0 0 3 3 3 0 Rad17 P-loop domain GCIP PF13324.6 CBY22428.1 - 0.38 10.3 3.2 0.26 10.9 0.2 2.3 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting MobB PF03205.14 CBY22428.1 - 0.59 10.0 2.2 18 5.2 0.0 3.4 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B CobU PF02283.16 CBY22428.1 - 2.1 7.9 6.5 1e+02 2.4 0.0 4.9 5 0 0 5 5 5 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Macoilin PF09726.9 CBY22430.1 - 3.4 6.1 9.7 4.1 5.9 9.7 1.0 1 0 0 1 1 1 0 Macoilin family Mob1_phocein PF03637.17 CBY22431.1 - 1.5e-32 112.9 0.6 2.5e-32 112.2 0.6 1.3 1 0 0 1 1 1 1 Mob1/phocein family zf-LITAF-like PF10601.9 CBY22432.1 - 1.2e-17 63.9 9.6 1.4e-17 63.7 9.6 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-RING_4 PF14570.6 CBY22432.1 - 0.45 10.4 10.5 0.69 9.8 4.1 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain JAMP PF05571.12 CBY22433.1 - 4.9e-08 33.0 7.9 6.2e-08 32.6 7.9 1.1 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein JAMP PF05571.12 CBY22434.1 - 1e-24 87.7 10.3 1.8e-24 86.9 10.3 1.3 1 1 0 1 1 1 1 JNK1/MAPK8-associated membrane protein zf-LITAF-like PF10601.9 CBY22435.1 - 2e-22 79.2 12.3 2.7e-22 78.8 12.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-LITAF-like PF10601.9 CBY22436.1 - 1.3e-16 60.6 23.1 1.7e-16 60.2 23.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain ATP_bind_3 PF01171.20 CBY22437.1 - 3.7e-17 62.7 0.0 1.6e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 CBY22437.1 - 1.1e-16 60.0 2.0 1.1e-16 60.0 2.0 3.3 3 0 0 3 3 3 1 Zinc-ribbon Memo PF01875.17 CBY22438.1 - 6.6e-48 163.2 0.2 7.3e-48 163.1 0.2 1.0 1 0 0 1 1 1 1 Memo-like protein PNPase PF03726.14 CBY22440.1 - 0.076 13.5 2.7 1.6 9.3 0.9 3.2 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain RVT_1 PF00078.27 CBY22441.1 - 1.6e-05 24.6 0.0 4.6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 CBY22441.1 - 0.00013 21.6 0.1 0.00029 20.5 0.1 1.6 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RT_RNaseH PF17917.1 CBY22441.1 - 0.098 12.9 0.2 0.54 10.6 0.2 2.2 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase VQ PF05678.14 CBY22442.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 VQ motif Memo PF01875.17 CBY22443.1 - 7.6e-33 113.8 0.0 8.2e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein TPR_19 PF14559.6 CBY22444.1 - 2.4e-12 47.2 3.5 6.1e-05 23.5 0.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY22444.1 - 6.9e-12 45.1 0.3 0.00035 21.2 0.2 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY22444.1 - 8.3e-10 38.0 7.1 0.00051 20.0 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY22444.1 - 3.3e-07 30.8 0.0 8e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY22444.1 - 6.3e-06 25.8 5.6 0.026 14.4 0.1 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY22444.1 - 1.2e-05 24.9 1.8 0.048 13.7 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY22444.1 - 1.9e-05 25.0 0.3 7 7.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY22444.1 - 3.1e-05 23.9 2.3 0.0045 17.1 0.6 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CBY22444.1 - 6.7e-05 22.9 0.0 0.0023 17.9 0.0 2.2 1 1 1 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_15 PF13429.6 CBY22444.1 - 0.00027 20.3 0.0 0.00076 18.8 0.1 1.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY22444.1 - 0.00057 20.1 2.0 8.9 6.9 0.0 4.6 5 1 0 5 5 4 1 Tetratricopeptide repeat NARP1 PF12569.8 CBY22444.1 - 0.00077 18.5 2.9 0.084 11.8 0.3 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 CBY22444.1 - 0.0041 17.4 2.1 0.084 13.2 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF4852 PF16144.5 CBY22444.1 - 0.021 14.9 0.1 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) TPR_9 PF13371.6 CBY22444.1 - 0.025 14.7 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 CBY22444.1 - 0.028 14.7 7.0 0.93 9.9 0.2 3.4 4 0 0 4 4 3 0 PPR repeat ChAPs PF09295.10 CBY22444.1 - 0.064 12.3 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) PknG_TPR PF16918.5 CBY22444.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat 2-oxoacid_dh PF00198.23 CBY22446.1 - 3.8e-66 222.9 0.0 4.2e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) VWA PF00092.28 CBY22447.1 - 4.4e-08 33.6 0.1 8.5e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain DUF3194 PF11419.8 CBY22448.1 - 0.15 12.5 0.1 0.21 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) Kinesin PF00225.23 CBY22449.1 - 9.2e-120 399.5 0.2 9.2e-120 399.5 0.2 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY22449.1 - 3.2e-24 85.6 0.2 9.1e-24 84.1 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Saf_2TM PF18303.1 CBY22449.1 - 0.18 11.3 1.0 0.35 10.4 1.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Hema_stalk PF08720.10 CBY22449.1 - 0.2 11.4 0.5 0.45 10.2 0.5 1.5 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk zf-C2H2_aberr PF17017.5 CBY22449.1 - 0.51 10.5 4.8 0.47 10.6 1.8 2.4 2 1 0 2 2 2 0 Aberrant zinc-finger Kinesin_assoc PF16183.5 CBY22449.1 - 0.83 9.8 8.9 17 5.5 8.9 2.7 1 1 0 1 1 1 0 Kinesin-associated zf-C2H2_4 PF13894.6 CBY22451.1 - 2e-42 140.2 129.7 0.0041 17.8 0.2 20.0 20 0 0 20 20 20 18 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY22451.1 - 1.5e-39 132.2 137.9 0.00028 21.2 0.3 20.1 20 1 0 20 20 20 16 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY22451.1 - 8.7e-19 67.3 118.5 0.027 14.8 0.6 19.7 20 0 0 20 20 20 12 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY22451.1 - 1e-12 47.8 123.2 0.024 15.1 0.3 20.3 20 0 0 20 20 20 12 Zinc-finger double domain zf-C2H2_11 PF16622.5 CBY22451.1 - 1.4e-12 47.1 61.4 0.024 14.4 1.0 14.8 17 0 0 17 17 16 6 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY22451.1 - 5.8e-12 45.3 117.5 0.0045 16.9 0.3 19.2 19 1 0 19 19 19 8 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CBY22451.1 - 2.5e-05 24.9 72.5 0.033 14.9 2.4 10.1 1 1 11 12 12 12 6 Zinc finger C2H2-type, 3 repeats zf_Hakai PF18408.1 CBY22451.1 - 0.00069 19.3 29.7 1.1 9.1 0.6 9.8 11 0 0 11 11 11 3 C2H2 Hakai zinc finger domain zinc_ribbon_15 PF17032.5 CBY22451.1 - 0.0039 17.9 4.8 0.0039 17.9 4.8 11.4 5 4 7 12 12 12 3 zinc-ribbon family zf-met PF12874.7 CBY22451.1 - 0.01 16.2 104.4 0.85 10.1 0.1 18.0 20 0 0 20 20 19 0 Zinc-finger of C2H2 type Trypan_PARP PF05887.11 CBY22451.1 - 0.89 9.5 14.0 1.8 8.5 4.9 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) zf-C2H2_8 PF15909.5 CBY22451.1 - 1.3 9.4 73.4 0.4 11.0 1.8 10.9 4 3 6 11 11 11 0 C2H2-type zinc ribbon bZIP_Maf PF03131.17 CBY22452.1 - 7e-20 71.3 5.8 7e-20 71.3 5.8 3.0 2 1 0 3 3 3 1 bZIP Maf transcription factor DUF641 PF04859.12 CBY22452.1 - 0.0021 18.4 8.4 0.0021 18.4 8.4 2.1 1 1 0 2 2 2 1 Plant protein of unknown function (DUF641) bZIP_1 PF00170.21 CBY22452.1 - 0.0088 16.1 1.6 0.0088 16.1 1.6 3.4 3 1 1 4 4 4 2 bZIP transcription factor POTRA PF07244.15 CBY22452.1 - 0.019 15.5 0.1 0.019 15.5 0.1 2.6 3 0 0 3 3 3 0 Surface antigen variable number repeat KfrA_N PF11740.8 CBY22452.1 - 0.02 15.6 5.1 0.81 10.4 0.0 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF3560 PF12083.8 CBY22452.1 - 0.19 11.8 7.1 0.71 10.0 7.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) TSC22 PF01166.18 CBY22452.1 - 0.34 11.3 4.7 0.49 10.7 0.4 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family HAUS-augmin3 PF14932.6 CBY22452.1 - 0.71 9.4 14.8 0.05 13.2 8.5 2.2 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 fn1 PF00039.18 CBY22453.1 - 0.0038 17.4 29.0 0.033 14.4 3.3 5.4 4 3 0 4 4 4 3 Fibronectin type I domain AAA_6 PF12774.7 CBY22454.1 - 9.7e-164 544.1 0.0 1.3e-161 537.0 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 CBY22454.1 - 2.6e-96 322.5 0.0 1.3e-95 320.2 0.0 2.2 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBY22454.1 - 3e-91 305.4 0.7 3.2e-90 302.0 0.2 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CBY22454.1 - 1.8e-63 213.3 1.0 2.5e-51 173.8 0.0 5.8 4 1 1 5 5 5 3 P-loop containing dynein motor region MT PF12777.7 CBY22454.1 - 8.2e-56 189.5 13.1 1.7e-55 188.5 13.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CBY22454.1 - 1.3e-54 184.4 0.0 2.9e-54 183.3 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBY22454.1 - 6e-42 142.5 0.0 2.5e-41 140.5 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 CBY22454.1 - 2.9e-41 141.0 1.4 1.1e-38 132.6 0.0 3.9 3 1 1 4 4 4 1 ATP-binding dynein motor region Dynein_AAA_lid PF17852.1 CBY22454.1 - 5.7e-26 91.1 0.0 2.6e-25 89.0 0.0 2.3 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBY22454.1 - 4.1e-23 81.5 0.2 2e-22 79.3 0.2 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBY22454.1 - 8.7e-17 61.4 0.0 2.1e-07 31.0 0.0 5.4 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 CBY22454.1 - 4.7e-09 36.8 0.3 0.24 11.8 0.0 4.2 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBY22454.1 - 8.7e-07 29.5 0.1 1.8 9.2 0.0 4.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CBY22454.1 - 2.6e-05 24.7 0.8 10 6.5 0.0 5.0 5 1 0 5 5 4 0 AAA ATPase domain AAA_22 PF13401.6 CBY22454.1 - 0.00039 20.7 1.8 0.26 11.5 0.0 4.1 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 CBY22454.1 - 0.0022 18.4 0.0 6.8 7.1 0.0 3.5 2 0 0 2 2 2 0 RNA helicase DUF853 PF05872.12 CBY22454.1 - 0.008 14.8 0.4 0.67 8.5 0.0 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) DUF4874 PF16173.5 CBY22454.1 - 0.027 14.1 1.3 1.1 8.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4874) TsaE PF02367.17 CBY22454.1 - 0.029 14.4 1.6 6.2 6.8 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 CBY22454.1 - 0.033 13.9 3.2 11 5.6 0.0 3.9 4 0 0 4 4 3 0 Cytidylate kinase AAA_30 PF13604.6 CBY22454.1 - 0.055 13.2 2.5 15 5.3 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CBY22454.1 - 0.093 13.0 2.1 32 4.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 CBY22454.1 - 0.097 11.7 0.9 1.5 7.8 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 CBY22454.1 - 0.099 12.3 0.3 14 5.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain COG2 PF06148.11 CBY22454.1 - 0.85 9.7 3.4 1.7 8.7 1.4 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 CBY22454.1 - 1.6 7.6 11.2 0.3 9.9 1.4 2.9 2 0 0 2 2 2 0 Spc7 kinetochore protein UvrD-helicase PF00580.21 CBY22454.1 - 3.8 6.9 7.7 0.95 8.9 0.6 3.0 3 0 0 3 3 2 0 UvrD/REP helicase N-terminal domain Phage_GP20 PF06810.11 CBY22454.1 - 4.9 6.9 18.2 4 7.2 10.3 2.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 DHC_N2 PF08393.13 CBY22455.1 - 1.2e-107 360.4 14.8 1.2e-107 360.4 14.8 3.3 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Coiled-coil_56 PF09813.9 CBY22456.1 - 0.024 14.7 0.4 0.2 11.7 0.0 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 56 DASH_Dad3 PF08656.10 CBY22456.1 - 0.11 12.6 2.2 0.14 12.3 0.3 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 HEAT PF02985.22 CBY22458.1 - 2.8e-12 45.8 2.5 0.34 11.3 0.0 5.6 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 CBY22458.1 - 5.6e-09 36.3 0.4 0.0024 18.2 0.0 4.0 2 2 1 3 3 3 3 HEAT repeats Adaptin_N PF01602.20 CBY22458.1 - 1.9e-08 33.4 1.6 2.7e-05 23.0 0.3 2.3 2 0 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CBY22458.1 - 2.7e-08 34.3 0.6 0.0015 19.1 0.0 4.6 2 2 2 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CBY22458.1 - 5e-07 29.9 4.3 0.14 12.1 0.5 4.9 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CBY22458.1 - 0.00076 19.6 0.2 0.051 13.8 0.0 3.3 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CBY22458.1 - 0.026 15.0 0.1 60 4.3 0.0 4.8 4 0 0 4 4 4 0 HEAT-like repeat ABC2_membrane_3 PF12698.7 CBY22459.1 - 1.8e-58 198.3 41.5 2.4e-38 132.1 14.3 2.7 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBY22459.1 - 6.6e-57 191.9 0.0 8.7e-28 97.6 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBY22459.1 - 1.7e-19 70.8 0.0 3.3e-07 30.4 0.0 4.6 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CBY22459.1 - 2.4e-08 34.6 0.3 0.00022 21.9 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) AAA_23 PF13476.6 CBY22459.1 - 0.00017 22.2 4.4 0.021 15.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 CBY22459.1 - 0.00048 20.0 0.1 1.5 8.4 0.0 3.4 4 0 0 4 4 4 2 AAA ATPase domain SRP54 PF00448.22 CBY22459.1 - 0.0012 18.5 0.6 1.7 8.2 0.1 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SMC_N PF02463.19 CBY22459.1 - 0.0014 18.1 0.0 3.1 7.2 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBY22459.1 - 0.016 14.9 0.6 0.63 9.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBY22459.1 - 0.016 15.1 0.6 0.26 11.2 0.1 2.6 3 0 0 3 3 3 0 RsgA GTPase AAA_30 PF13604.6 CBY22459.1 - 0.065 12.9 0.0 8.8 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 CBY22459.1 - 0.074 12.8 0.9 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_22 PF13401.6 CBY22459.1 - 0.076 13.3 0.1 24 5.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain LAMTOR5 PF16672.5 CBY22460.1 - 7.7e-05 22.6 0.0 9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Serpin PF00079.20 CBY22461.1 - 3.8e-22 79.1 0.1 1.9e-19 70.2 0.0 2.0 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) ETC_C1_NDUFA5 PF04716.14 CBY22462.1 - 1.2e-12 47.4 0.1 2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Fer2 PF00111.27 CBY22463.1 - 5.2e-07 29.5 0.8 8.8e-07 28.8 0.8 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Nicastrin PF05450.15 CBY22464.1 - 4.3e-09 36.2 0.0 7.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 CBY22464.1 - 3.1e-05 23.8 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 RNA_pol_Rpb2_2 PF04561.14 CBY22464.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 TTKRSYEDQ PF10212.9 CBY22465.1 - 2.3e-07 30.2 13.2 2.3e-07 30.2 13.2 1.9 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein DUF948 PF06103.11 CBY22465.1 - 1.4 9.2 7.4 13 6.1 0.4 3.5 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) YscO-like PF16789.5 CBY22465.1 - 5.5 7.0 19.4 0.83 9.7 1.4 2.4 2 0 0 2 2 2 0 YscO-like protein Med6 PF04934.14 CBY22467.1 - 3e-33 114.5 0.1 4.7e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Y1_Tnp PF01797.16 CBY22467.1 - 0.057 13.5 0.4 0.57 10.3 0.1 2.6 3 1 1 4 4 4 0 Transposase IS200 like LRR_8 PF13855.6 CBY22468.1 - 5.2e-13 48.6 14.6 6.5e-07 29.0 1.9 4.5 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 CBY22468.1 - 9.2e-11 41.8 32.4 2.9e-05 24.3 2.3 5.1 2 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY22468.1 - 1.4e-06 27.9 1.2 1.4e-06 27.9 1.2 3.5 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 CBY22468.1 - 0.0012 18.8 9.8 1.2 9.4 0.2 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 CBY22468.1 - 0.0028 17.9 6.8 4.1 8.3 0.3 5.0 5 0 0 5 5 5 1 Leucine Rich Repeat HSBP1 PF06825.12 CBY22468.1 - 0.018 14.9 4.8 0.018 14.9 4.8 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Gal11_ABD1 PF18535.1 CBY22468.1 - 0.021 14.9 0.7 0.021 14.9 0.7 2.7 3 0 0 3 3 3 0 Gal11 activator-binding domain (ABD1) Sigma70_r4_2 PF08281.12 CBY22468.1 - 0.031 14.0 0.2 0.12 12.0 0.2 2.1 1 0 0 1 1 1 0 Sigma-70, region 4 RTBV_P46 PF06216.11 CBY22469.1 - 0.02 13.8 3.9 0.18 10.7 3.9 2.2 1 1 0 1 1 1 0 Rice tungro bacilliform virus P46 protein TOPRIM_C PF16898.5 CBY22469.1 - 2.4 8.5 8.6 0.6 10.4 0.1 3.2 2 2 0 2 2 2 0 C-terminal associated domain of TOPRIM Anthrax_toxA PF03497.16 CBY22469.1 - 2.7 8.1 15.2 0.14 12.2 3.4 2.8 2 2 0 2 2 2 0 Anthrax toxin LF subunit Trimer_CC PF08954.11 CBY22469.1 - 3.8 7.1 12.2 7.5 6.2 0.2 4.5 4 0 0 4 4 4 0 Trimerisation motif PKcGMP_CC PF16808.5 CBY22469.1 - 6.7 6.7 31.7 0.98 9.3 0.3 7.1 6 2 1 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sulfate_transp PF00916.20 CBY22470.1 - 2.5e-72 243.8 22.6 3.8e-72 243.1 22.6 1.3 1 0 0 1 1 1 1 Sulfate permease family Sulfotransfer_2 PF03567.14 CBY22471.1 - 1.7e-17 64.2 1.3 1.7e-17 64.2 1.3 1.7 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY22471.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase domain EGF_CA PF07645.15 CBY22472.1 - 3.7e-25 87.8 39.9 6.7e-10 39.0 8.4 4.6 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.7 CBY22472.1 - 3.6e-07 30.0 27.2 0.00017 21.4 2.1 4.9 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY22472.1 - 0.096 12.9 33.6 0.39 10.9 6.3 4.3 4 0 0 4 4 4 0 EGF domain GBP_PSP PF02425.15 CBY22472.1 - 0.54 9.9 11.3 3.1 7.5 0.1 4.4 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Vanabin-2 PF11437.8 CBY22472.1 - 2.7 8.2 34.1 1.2 9.3 4.9 3.6 1 1 2 3 3 3 0 Vanadium-binding protein 2 TIL PF01826.17 CBY22472.1 - 3.5 8.0 37.6 0.69 10.2 4.2 4.5 4 0 0 4 4 4 0 Trypsin Inhibitor like cysteine rich domain EF-hand_1 PF00036.32 CBY22473.1 - 6.2e-39 128.7 13.6 7.5e-09 34.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY22473.1 - 3.5e-33 113.9 7.1 3.9e-16 59.2 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY22473.1 - 2e-31 105.2 8.8 1.1e-08 34.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBY22473.1 - 1.1e-27 94.2 19.4 6.5e-09 34.9 0.1 4.4 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CBY22473.1 - 7.8e-27 92.9 11.2 9.6e-11 41.4 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CBY22473.1 - 7.8e-19 67.8 0.4 4.2e-09 36.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBY22473.1 - 4.2e-13 49.2 4.4 9e-07 28.8 0.5 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY22473.1 - 1.8e-07 31.4 0.7 0.00015 22.0 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBY22473.1 - 1.1e-05 26.2 0.0 0.00046 21.0 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CBY22473.1 - 5.6e-05 23.3 1.8 0.1 12.8 0.1 3.2 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 CBY22473.1 - 6.1e-05 21.8 0.0 7.4e-05 21.5 0.0 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF5580) VCBS PF13517.6 CBY22473.1 - 0.00014 22.4 0.0 0.053 14.1 0.0 2.3 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SurA_N_2 PF13623.6 CBY22473.1 - 0.0021 18.0 1.0 0.0032 17.3 0.9 1.3 1 1 0 1 1 1 1 SurA N-terminal domain EF-hand_14 PF17959.1 CBY22473.1 - 0.0023 18.3 0.6 0.45 10.9 0.1 2.5 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 CBY22473.1 - 0.0048 16.9 1.0 0.41 10.6 0.1 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB UPF0154 PF03672.13 CBY22473.1 - 0.0082 16.2 0.0 1.5 8.9 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Phage_CP76 PF06892.11 CBY22473.1 - 0.01 15.3 0.2 0.015 14.9 0.2 1.1 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) DUF2666 PF10869.8 CBY22473.1 - 0.024 14.9 0.3 4.3 7.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) VbhA PF18495.1 CBY22473.1 - 0.038 13.9 2.0 22 5.0 0.1 3.6 4 0 0 4 4 3 0 Antitoxin VbhA Caleosin PF05042.13 CBY22473.1 - 0.053 13.5 0.9 5.7 6.8 0.0 3.1 2 2 1 3 3 3 0 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CBY22473.1 - 0.055 13.8 2.0 0.8 10.0 0.2 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 Adenine_glyco PF03352.13 CBY22473.1 - 0.073 12.8 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyladenine glycosylase PDZ_1 PF12812.7 CBY22473.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 PDZ-like domain PMBR PF09373.10 CBY22473.1 - 0.11 12.7 0.1 1.2e+02 3.1 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat TcdB_toxin_midN PF12256.8 CBY22473.1 - 0.19 11.0 0.8 1.1 8.6 0.0 2.4 1 1 2 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region NIR_SIR_ferr PF03460.17 CBY22473.1 - 0.22 11.4 0.9 13 5.7 0.0 3.2 3 1 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain UBA_6 PF18039.1 CBY22473.1 - 0.33 10.9 1.9 24 5.0 0.2 2.6 2 1 0 2 2 2 0 UBA-like domain EF-hand_10 PF14788.6 CBY22473.1 - 0.4 10.6 3.8 3 7.8 0.2 3.1 3 0 0 3 3 3 0 EF hand DUF533 PF04391.12 CBY22473.1 - 4.9 6.7 7.8 17 4.9 5.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF533) GSHPx PF00255.19 CBY22474.1 - 4.9e-23 80.8 0.1 6.6e-23 80.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase EKR PF10371.9 CBY22474.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function La PF05383.17 CBY22475.1 - 2.1e-19 69.3 0.5 5.2e-19 68.1 0.3 1.8 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 CBY22475.1 - 0.012 15.4 0.1 0.86 9.5 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5434 PF17502.2 CBY22475.1 - 0.23 11.4 4.8 0.46 10.5 4.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5434) Cys_Met_Meta_PP PF01053.20 CBY22476.1 - 1.1e-149 498.2 0.0 1.2e-149 498.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CBY22476.1 - 2.6e-06 26.2 0.0 7.9e-06 24.6 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 CBY22476.1 - 5e-06 25.7 0.6 8.1e-05 21.7 0.4 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CBY22476.1 - 0.00053 19.3 0.1 0.00084 18.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II CPT PF07931.12 CBY22476.1 - 0.092 12.6 0.2 0.2 11.5 0.2 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arm PF00514.23 CBY22477.1 - 0.00036 20.5 0.3 1 9.5 0.0 4.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat LRR_4 PF12799.7 CBY22477.1 - 0.0052 17.2 3.3 2.2 8.8 0.2 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 CBY22478.1 - 1.8e-19 69.3 1.2 1.7e-12 47.0 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HopJ PF08888.11 CBY22478.1 - 0.077 13.2 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 HopJ type III effector protein RRM_occluded PF16842.5 CBY22478.1 - 0.14 12.1 0.0 0.65 9.9 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif Vinculin PF01044.19 CBY22479.1 - 8.3e-226 752.5 38.8 1.5e-158 529.9 28.3 2.3 1 1 1 2 2 2 2 Vinculin family Peptidase_S21 PF00716.17 CBY22479.1 - 0.059 13.1 0.6 0.1 12.2 0.6 1.3 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) PHA_synth_III_E PF09712.10 CBY22479.1 - 0.13 11.4 0.0 0.13 11.4 0.0 3.2 4 0 0 4 4 4 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Collagen_mid PF15984.5 CBY22479.1 - 0.27 11.0 0.0 0.27 11.0 0.0 3.1 4 0 0 4 4 4 0 Bacterial collagen, middle region DUF1798 PF08807.10 CBY22479.1 - 1.1 9.4 5.8 55 4.0 0.1 4.7 4 0 0 4 4 4 0 Bacterial domain of unknown function (DUF1798) GIT1_C PF12205.8 CBY22479.1 - 6.4 6.9 21.9 0.96 9.6 0.2 6.5 4 1 2 7 7 7 0 G protein-coupled receptor kinase-interacting protein 1 C term AAA_12 PF13087.6 CBY22480.1 - 2.5e-26 92.5 0.1 4.2e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBY22480.1 - 4.1e-10 39.9 0.0 1.1e-09 38.5 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 CBY22480.1 - 4.9e-08 32.9 0.0 7.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY22480.1 - 7.4e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CBY22480.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CBY22480.1 - 0.0002 21.4 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBY22480.1 - 0.0082 16.4 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CBY22480.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Helicase G-alpha PF00503.20 CBY22482.1 - 9.2e-104 347.4 2.7 1.1e-103 347.1 2.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY22482.1 - 1.3e-16 60.5 1.5 1.5e-13 50.6 0.4 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY22482.1 - 3e-05 23.5 2.2 0.00044 19.7 0.2 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CBY22482.1 - 0.00023 21.3 0.8 0.064 13.5 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CBY22482.1 - 0.00093 18.8 0.0 0.081 12.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CBY22482.1 - 0.05 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CBY22482.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein tRNA-synt_1g PF09334.11 CBY22483.1 - 5.5e-11 41.8 0.0 9.4e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) ubiquitin PF00240.23 CBY22483.1 - 0.0066 16.2 0.6 0.013 15.2 0.2 1.7 1 1 1 2 2 2 1 Ubiquitin family Ank_4 PF13637.6 CBY22484.1 - 1.7e-12 47.6 1.2 6e-07 29.9 0.2 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY22484.1 - 1.4e-09 38.4 0.1 3.6e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY22484.1 - 6.2e-07 29.6 0.1 2e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY22484.1 - 9.6e-06 25.6 0.1 0.0015 18.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CBY22484.1 - 0.00018 21.8 0.0 0.0016 18.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat SAM_1 PF00536.30 CBY22484.1 - 0.0043 17.4 0.1 0.012 16.1 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PUF PF00806.19 CBY22484.1 - 0.14 11.9 0.2 34 4.4 0.1 3.0 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat tRNA-synt_1g PF09334.11 CBY22485.1 - 1.1e-119 399.7 2.6 1.5e-119 399.3 2.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CBY22485.1 - 2.1e-05 24.5 0.0 4.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PITH PF06201.13 CBY22487.1 - 2.4e-39 135.0 1.2 2.8e-39 134.8 1.2 1.0 1 0 0 1 1 1 1 PITH domain Pkinase PF00069.25 CBY22488.1 - 9.8e-63 212.0 0.0 2e-62 211.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22488.1 - 4.1e-48 163.9 0.0 6.9e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 CBY22488.1 - 1.2e-16 60.5 2.9 1.2e-16 60.5 2.9 2.0 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 CBY22488.1 - 4.2e-06 25.8 0.4 4.3e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase CorA PF01544.18 CBY22488.1 - 0.072 12.4 0.4 0.15 11.3 0.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ABC1 PF03109.16 CBY22488.1 - 0.12 12.6 0.0 3.2 7.9 0.0 2.9 3 0 0 3 3 3 0 ABC1 family Vpu PF00558.19 CBY22488.1 - 0.42 10.4 2.0 0.91 9.3 2.0 1.5 1 0 0 1 1 1 0 Vpu protein RabGAP-TBC PF00566.18 CBY22489.1 - 2.8e-54 184.0 1.4 3.8e-54 183.6 1.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4864 PF16156.5 CBY22489.1 - 0.029 15.1 0.0 0.061 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) IFP_35_N PF07334.13 CBY22489.1 - 4.5 7.4 5.5 85 3.3 0.0 2.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PH PF00169.29 CBY22490.1 - 1.7e-05 25.3 1.5 3.1e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 PH domain Hamartin PF04388.12 CBY22491.1 - 4.7 5.8 19.8 5.2 5.6 19.8 1.3 1 0 0 1 1 1 0 Hamartin protein Polysacc_lyase PF14099.6 CBY22493.1 - 0.038 13.8 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase PQ-loop PF04193.14 CBY22493.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 PQ loop repeat Polysacc_lyase PF14099.6 CBY22494.1 - 0.00041 20.3 0.1 0.00069 19.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase TAF8_C PF10406.9 CBY22495.1 - 4.8e-11 43.0 0.0 1e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 CBY22495.1 - 1.2e-08 34.8 0.2 2.3e-07 30.7 0.1 2.2 2 0 0 2 2 2 1 Bromodomain associated Peptidase_C14 PF00656.22 CBY22496.1 - 8.3e-12 45.6 0.0 1.4e-11 44.8 0.0 1.3 1 1 0 1 1 1 1 Caspase domain FAST_1 PF06743.15 CBY22496.1 - 0.097 12.6 0.0 0.81 9.7 0.0 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Peptidase_C14 PF00656.22 CBY22497.1 - 1.8e-13 51.0 0.0 2.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 CBY22498.1 - 2.9e-07 30.7 0.1 0.003 17.6 0.0 2.1 2 0 0 2 2 2 2 Caspase domain N6-adenineMlase PF10237.9 CBY22499.1 - 1.7e-23 83.2 0.4 2.2e-23 82.8 0.4 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 CBY22499.1 - 0.0099 15.5 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RVT_1 PF00078.27 CBY22502.1 - 3.5e-16 59.4 0.0 1.5e-15 57.4 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NOA36 PF06524.12 CBY22502.1 - 0.58 9.4 2.5 0.31 10.3 0.1 1.6 2 0 0 2 2 2 0 NOA36 protein MOZ_SAS PF01853.18 CBY22503.1 - 1.3e-68 230.2 0.2 1.9e-68 229.6 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY22503.1 - 4.4e-17 61.4 6.5 6.3e-17 60.9 3.6 2.3 2 0 0 2 2 2 1 MYST family zinc finger domain zf-C2HC PF01530.18 CBY22503.1 - 1e-10 41.6 0.3 2.2e-10 40.5 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 CBY22503.1 - 0.0036 17.7 0.0 0.0084 16.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.6 CBY22503.1 - 0.27 12.2 3.7 1.1 10.3 3.7 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger W_rich_C PF07483.11 CBY22504.1 - 3.7 7.7 7.8 0.28 11.4 1.1 2.4 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain WD40 PF00400.32 CBY22505.1 - 3.6e-06 27.6 2.6 0.081 13.8 0.0 3.6 4 1 0 4 4 4 2 WD domain, G-beta repeat Put_Phosphatase PF06888.12 CBY22505.1 - 0.064 12.6 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Putative Phosphatase WD40 PF00400.32 CBY22506.1 - 3.1e-06 27.8 0.1 5.3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat CRS1_YhbY PF01985.21 CBY22506.1 - 0.033 14.4 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain TMEM214 PF10151.9 CBY22506.1 - 0.12 10.8 3.3 0.14 10.6 3.3 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator BIR PF00653.21 CBY22508.1 - 4.7 7.9 8.4 24 5.7 0.1 4.3 5 0 0 5 5 5 0 Inhibitor of Apoptosis domain MPC PF03650.13 CBY22509.1 - 7.3e-11 42.2 0.0 8.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Glyco_hydro_38C PF07748.13 CBY22509.1 - 0.2 11.7 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain Ldl_recept_a PF00057.18 CBY22510.1 - 4.7e-05 23.5 4.6 9.5e-05 22.5 4.6 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF4726 PF15855.5 CBY22511.1 - 0.076 13.2 0.0 2.6 8.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4726) TLV_coat PF00429.19 CBY22511.1 - 0.083 11.6 0.0 0.22 10.1 0.0 1.6 2 0 0 2 2 2 0 ENV polyprotein (coat polyprotein) Baculo_PEP_C PF04513.12 CBY22511.1 - 0.13 12.3 0.6 31 4.6 0.1 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.9 CBY22511.1 - 0.13 12.5 0.0 0.58 10.4 0.0 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein DUF5344 PF17279.2 CBY22511.1 - 0.43 11.2 2.2 0.81 10.3 0.4 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Homeodomain PF00046.29 CBY22512.1 - 1.2e-22 79.5 4.1 3e-22 78.2 4.1 1.7 1 0 0 1 1 1 1 Homeodomain Engrail_1_C_sig PF10525.9 CBY22512.1 - 2.2e-11 42.7 0.0 4.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain Homeobox_KN PF05920.11 CBY22512.1 - 0.00097 19.0 0.7 0.0018 18.2 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 CBY22512.1 - 0.0048 16.3 0.3 0.0073 15.8 0.3 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF2316 PF10078.9 CBY22512.1 - 0.061 13.6 0.3 0.096 12.9 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) zf-met PF12874.7 CBY22513.1 - 4.3e-14 52.3 4.4 4.3e-07 30.1 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY22513.1 - 5.6e-14 52.0 3.5 2e-06 27.9 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY22513.1 - 6.8e-08 32.8 0.2 0.0069 16.7 0.0 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBY22513.1 - 1.5e-05 25.4 0.6 0.22 12.5 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY22513.1 - 4.7e-05 23.6 1.9 0.17 12.4 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 CBY22513.1 - 0.0002 21.2 0.6 0.027 14.3 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) AKAP95 PF04988.12 CBY22513.1 - 0.00036 20.8 0.2 0.55 10.4 0.0 2.4 2 0 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-Di19 PF05605.12 CBY22513.1 - 0.005 17.1 4.1 0.15 12.3 0.1 2.6 3 0 0 3 3 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CBY22513.1 - 0.021 14.8 4.2 3.1 7.9 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Actin_micro PF17003.5 CBY22513.1 - 0.12 11.6 0.6 1.7 7.8 0.6 2.0 1 1 0 1 1 1 0 Putative actin-like family C1_2 PF03107.16 CBY22513.1 - 0.14 12.5 1.5 2.7 8.4 0.0 2.4 2 0 0 2 2 2 0 C1 domain EF-hand_1 PF00036.32 CBY22514.1 - 9.1e-11 40.5 1.1 0.00073 18.9 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY22514.1 - 4.1e-09 35.6 0.2 0.0017 18.1 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY22514.1 - 7.4e-09 35.9 0.5 0.0033 17.9 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY22514.1 - 3.5e-08 32.6 2.3 0.0079 15.7 0.5 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY22514.1 - 1.7e-07 30.9 3.7 0.0015 18.3 0.4 3.5 3 1 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY22514.1 - 3.8e-05 24.0 0.1 0.18 12.2 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY22514.1 - 0.48 10.4 4.5 9 6.3 0.1 3.4 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand DUF4572 PF15139.6 CBY22515.1 - 1.2e-26 93.8 1.3 2.1e-26 93.1 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) DUF1690 PF07956.11 CBY22516.1 - 0.69 10.3 12.7 1.6 9.2 4.9 2.5 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Trypsin PF00089.26 CBY22517.1 - 2.4e-48 164.9 3.2 2.4e-48 164.9 3.2 2.1 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY22517.1 - 7.6e-05 23.6 0.0 0.00016 22.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain I-set PF07679.16 CBY22519.1 - 6.2e-13 48.6 0.0 8.9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY22519.1 - 1.5e-12 47.9 0.1 2.1e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY22519.1 - 1e-10 41.6 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY22519.1 - 3e-08 33.9 0.0 4.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_4 PF16680.5 CBY22519.1 - 0.0028 17.9 0.1 0.0059 16.8 0.0 1.6 1 1 1 2 2 2 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 CBY22519.1 - 0.043 13.9 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain dsRBD2 PF17842.1 CBY22519.1 - 0.11 12.6 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 Ig_5 PF16681.5 CBY22519.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Rod_cone_degen PF15201.6 CBY22519.1 - 0.9 9.7 3.2 13 5.9 3.2 2.5 1 1 0 1 1 1 0 Progressive rod-cone degeneration Ig_3 PF13927.6 CBY22520.1 - 3.1e-09 37.3 0.0 7.8e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CBY22520.1 - 1.6e-08 34.5 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY22520.1 - 0.0038 17.5 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY22520.1 - 0.045 13.9 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 CBY22520.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Lectin_C PF00059.21 CBY22521.1 - 1.1e-06 29.4 0.1 1.1e-06 29.4 0.1 2.5 2 1 0 2 2 2 1 Lectin C-type domain DUF4718 PF15842.5 CBY22521.1 - 0.06 13.1 4.3 0.12 12.2 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Microtub_bd PF16796.5 CBY22523.1 - 8.4e-06 25.8 0.0 2.6e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 CBY22523.1 - 0.00018 20.6 0.1 0.0022 17.0 0.0 2.7 2 2 1 3 3 3 1 Kinesin motor domain PTPS PF01242.19 CBY22524.1 - 2.2e-30 105.2 0.2 2.4e-30 105.0 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase YPEB PF14620.6 CBY22525.1 - 0.11 11.8 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 YpeB sporulation N6-adenineMlase PF10237.9 CBY22526.1 - 1.6e-38 132.0 0.3 2.4e-38 131.4 0.3 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 CBY22526.1 - 0.18 11.4 0.5 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DUF4882 PF16223.5 CBY22527.1 - 0.12 11.6 0.2 0.14 11.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) Tim44 PF04280.15 CBY22529.1 - 1.3e-36 126.0 0.2 1.3e-36 126.0 0.2 1.8 2 0 0 2 2 2 1 Tim44-like domain OmpH PF03938.14 CBY22529.1 - 0.12 12.7 11.6 0.04 14.2 7.7 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2408 PF10303.9 CBY22529.1 - 0.17 12.5 4.7 0.16 12.5 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Bacillus_HBL PF05791.11 CBY22529.1 - 0.42 10.4 8.4 0.1 12.4 4.8 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1690 PF07956.11 CBY22529.1 - 0.55 10.6 7.4 1.3 9.5 6.5 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Sec63 PF02889.16 CBY22530.1 - 1.4e-132 440.6 0.2 2.8e-69 233.2 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBY22530.1 - 4.5e-51 173.1 2.8 4.2e-24 85.3 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 CBY22530.1 - 1.5e-26 93.4 0.0 3.7e-13 49.8 0.2 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBY22530.1 - 3.4e-16 59.6 0.5 8.2e-07 29.4 0.0 4.6 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CBY22530.1 - 1.1e-07 32.2 1.6 0.024 14.9 0.2 3.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CBY22530.1 - 4.3e-07 30.4 0.9 0.0077 16.6 1.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CBY22530.1 - 1.3e-06 28.3 0.1 0.0082 15.9 0.2 2.7 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 CBY22530.1 - 0.00013 22.1 0.5 0.0024 18.0 0.1 2.8 2 0 0 2 2 2 1 N-terminal helicase PWI domain UvrD-helicase PF00580.21 CBY22530.1 - 0.0046 16.5 0.3 0.17 11.4 0.0 3.0 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 CBY22530.1 - 0.014 14.4 0.0 1.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 CBY22530.1 - 0.017 15.5 0.1 9.9 6.5 0.1 3.6 2 1 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 CBY22530.1 - 0.026 14.0 0.0 4 6.8 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein PTS_IIB PF02302.17 CBY22530.1 - 0.098 13.4 0.3 3.8 8.3 0.0 3.0 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit DUF4406 PF14359.6 CBY22530.1 - 0.14 12.6 0.0 0.55 10.8 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) DnaB_C PF03796.15 CBY22530.1 - 0.44 9.8 3.5 0.63 9.3 1.6 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Myb_DNA-binding PF00249.31 CBY22532.1 - 1.5e-13 50.7 1.0 4.7e-07 29.9 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY22532.1 - 0.0028 17.9 11.7 0.056 13.7 0.6 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF2090 PF09863.9 CBY22532.1 - 0.043 12.8 2.6 0.082 11.9 2.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) pKID PF02173.17 CBY22532.1 - 0.62 9.6 4.5 0.76 9.3 0.7 2.7 2 0 0 2 2 2 0 pKID domain FAM167 PF11652.8 CBY22532.1 - 9.9 6.7 10.7 1.1 9.8 1.5 3.4 3 1 1 4 4 4 0 FAM167 HORMA PF02301.18 CBY22533.1 - 2.7e-23 82.7 0.1 3.4e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 HORMA domain Stork_head PF10264.9 CBY22534.1 - 2.3e-24 85.3 0.6 4.8e-24 84.3 0.2 1.8 2 0 0 2 2 2 1 Winged helix Storkhead-box1 domain Sema PF01403.19 CBY22535.1 - 0.009 14.9 1.2 0.009 14.9 1.2 2.5 2 1 0 3 3 3 1 Sema domain CPSF100_C PF13299.6 CBY22535.1 - 1.9 8.7 4.8 1.6 8.9 0.8 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EF-hand_7 PF13499.6 CBY22536.1 - 1.6e-13 50.9 4.7 9.8e-05 22.7 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBY22536.1 - 1.9e-13 48.9 5.9 0.00069 19.0 0.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBY22536.1 - 1.1e-12 46.8 6.2 0.0026 17.6 0.2 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CBY22536.1 - 3e-06 26.5 4.6 0.011 15.3 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY22536.1 - 0.00085 19.1 9.1 0.47 10.4 0.1 3.6 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_10 PF14788.6 CBY22536.1 - 0.015 15.1 3.6 0.027 14.3 1.3 2.5 2 1 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 CBY22536.1 - 0.046 13.7 3.9 0.94 9.5 0.4 2.7 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand ASC PF00858.24 CBY22537.1 - 3.1e-31 108.8 6.3 4e-31 108.5 6.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel VWA PF00092.28 CBY22538.1 - 3.4e-39 134.9 1.8 1.2e-38 133.1 0.6 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY22538.1 - 3.5e-11 43.7 0.0 9.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Sgf11_N PF18519.1 CBY22538.1 - 0.089 12.4 0.1 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain TSP_1 PF00090.19 CBY22539.1 - 1.3e-120 393.5 432.6 6.9e-09 35.8 10.0 30.0 31 1 1 32 32 32 24 Thrombospondin type 1 domain VWA PF00092.28 CBY22539.1 - 2.5e-09 37.7 0.0 3.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Homeodomain PF00046.29 CBY22540.1 - 4.6e-21 74.4 7.7 9.4e-21 73.4 7.7 1.6 1 0 0 1 1 1 1 Homeodomain RNA_pol_Rpc4 PF05132.14 CBY22540.1 - 0.069 13.6 3.1 0.1 13.0 3.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPN2_C PF18004.1 CBY22540.1 - 0.3 11.0 14.0 0.5 10.3 14.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 CBY22540.1 - 0.91 8.2 5.9 1.4 7.6 5.9 1.3 1 0 0 1 1 1 0 Presenilin DUF4632 PF15451.6 CBY22540.1 - 1.2 9.3 4.3 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) FAM176 PF14851.6 CBY22540.1 - 1.2 8.8 6.2 2.4 7.8 6.2 1.6 1 0 0 1 1 1 0 FAM176 family ABC_trans_N PF14510.6 CBY22540.1 - 1.6 9.4 4.6 3.5 8.3 4.6 1.5 1 0 0 1 1 1 0 ABC-transporter N-terminal Connexin PF00029.19 CBY22540.1 - 3.4 7.3 5.6 6 6.6 5.6 1.4 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 CBY22540.1 - 6 6.6 13.3 10 5.8 13.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.6 CBY22540.1 - 8.9 6.8 14.3 1.9 8.9 9.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TB2_DP1_HVA22 PF03134.19 CBY22541.1 - 1.9e-29 101.4 5.6 3.3e-29 100.6 5.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TMEM220 PF15071.6 CBY22541.1 - 5.3 7.9 6.9 58 4.5 5.8 2.7 2 1 0 2 2 2 0 Transmembrane family 220, helix ABC_tran PF00005.27 CBY22542.1 - 3.2e-46 157.3 0.0 4.9e-29 101.6 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBY22542.1 - 2.2e-40 139.1 19.8 2.6e-23 83.1 2.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CBY22542.1 - 1.6e-11 44.1 0.0 0.00018 21.0 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY22542.1 - 6.3e-05 23.4 0.1 0.41 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CBY22542.1 - 0.00019 21.4 1.8 10 5.9 0.0 4.5 3 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CBY22542.1 - 0.00021 21.4 0.7 0.064 13.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY22542.1 - 0.00054 19.9 0.5 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CBY22542.1 - 0.0045 17.3 1.5 2.3 8.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CBY22542.1 - 0.0089 15.3 0.4 1.4 8.2 0.1 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_29 PF13555.6 CBY22542.1 - 0.061 13.1 2.1 5.2 6.9 0.4 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 CBY22542.1 - 0.091 11.8 0.2 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.7 CBY22542.1 - 0.13 11.2 0.4 0.94 8.3 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain TrwB_AAD_bind PF10412.9 CBY22542.1 - 0.2 10.6 0.3 3 6.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CBY22542.1 - 0.23 11.5 3.4 0.2 11.7 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Acyltransf_C PF16076.5 CBY22543.1 - 0.012 15.7 0.5 0.066 13.3 0.0 2.2 2 1 0 2 2 2 0 Acyltransferase C-terminus AAA_33 PF13671.6 CBY22543.1 - 0.033 14.3 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cluap1 PF10234.9 CBY22544.1 - 0.075 12.4 4.8 0.081 12.3 4.3 1.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 zf-FCS PF06467.14 CBY22544.1 - 0.082 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Acyltransferase PF01553.21 CBY22545.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4440 PF14534.6 CBY22545.1 - 0.18 12.2 0.0 0.71 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) HAD_2 PF13419.6 CBY22546.1 - 5.7e-16 59.1 0.0 7.5e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY22546.1 - 1.3e-10 42.0 0.0 1.9e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY22546.1 - 3.5e-05 23.8 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4235 PF14019.6 CBY22546.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Got1 PF04178.12 CBY22547.1 - 6.1e-05 23.4 5.3 9.1e-05 22.9 5.3 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family RWD PF05773.22 CBY22549.1 - 0.00062 20.0 0.2 0.00086 19.6 0.2 1.3 1 1 0 1 1 1 1 RWD domain KxDL PF10241.9 CBY22549.1 - 0.13 12.5 0.4 0.32 11.3 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein RIO1 PF01163.22 CBY22551.1 - 1.4e-50 171.5 0.1 3.2e-50 170.4 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CBY22551.1 - 6.7e-28 96.7 0.2 4e-27 94.2 0.0 2.5 4 0 0 4 4 4 1 Rio2, N-terminal APH PF01636.23 CBY22551.1 - 1.7e-12 47.8 1.3 1.5e-05 25.1 0.0 3.5 2 1 1 3 3 3 3 Phosphotransferase enzyme family Kdo PF06293.14 CBY22551.1 - 1.4e-07 31.1 1.4 0.0087 15.4 0.0 3.0 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CBY22551.1 - 4.7e-06 26.2 1.2 1.3e-05 24.7 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain WaaY PF06176.11 CBY22551.1 - 0.0048 16.5 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RRM_1 PF00076.22 CBY22552.1 - 1.8e-28 98.2 0.0 1.4e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY22552.1 - 6.7e-09 35.7 0.4 0.0017 18.3 0.0 2.6 2 1 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 CBY22552.1 - 8.3e-09 35.3 0.0 5.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CBY22552.1 - 2.8e-06 27.1 0.0 0.00021 21.1 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif DbpA PF03880.15 CBY22552.1 - 3.3e-05 23.8 0.4 0.0065 16.4 0.1 2.6 3 0 0 3 3 3 1 DbpA RNA binding domain Limkain-b1 PF11608.8 CBY22552.1 - 0.00048 20.2 0.4 0.29 11.2 0.1 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 CBY22552.1 - 0.0022 17.6 0.0 0.005 16.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3110 PF11360.8 CBY22552.1 - 0.055 13.7 0.1 18 5.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3110) ArgoMid PF16487.5 CBY22552.1 - 0.066 13.5 0.0 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Mid domain of argonaute ATP-synt_D PF01813.17 CBY22553.1 - 0.0017 18.2 1.8 0.0025 17.6 1.8 1.2 1 0 0 1 1 1 1 ATP synthase subunit D HEAT PF02985.22 CBY22553.1 - 0.065 13.5 1.2 7.1 7.2 0.6 3.0 1 1 1 2 2 2 0 HEAT repeat ACOX PF01756.19 CBY22553.1 - 0.12 11.9 2.0 0.24 10.9 1.1 1.8 1 1 0 2 2 2 0 Acyl-CoA oxidase Arm PF00514.23 CBY22553.1 - 0.32 11.1 2.6 5.9 7.1 0.3 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ABC_tran PF00005.27 CBY22554.1 - 2.3e-50 170.6 0.1 3.9e-25 89.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CBY22554.1 - 9.5e-18 65.0 0.2 0.00032 20.6 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 CBY22554.1 - 3.7e-14 52.5 7.6 3.7e-14 52.5 7.6 3.4 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.19 CBY22554.1 - 7.2e-09 35.4 0.4 0.13 11.7 0.0 3.7 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CBY22554.1 - 3.7e-08 33.8 0.0 0.00073 19.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CBY22554.1 - 3.5e-07 29.9 0.0 0.0048 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_14 PF13173.6 CBY22554.1 - 1.2e-06 28.6 0.5 0.01 15.9 0.0 3.4 4 1 0 4 4 3 2 AAA domain AAA_23 PF13476.6 CBY22554.1 - 2.8e-06 28.0 0.5 0.00089 19.8 0.3 4.4 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.6 CBY22554.1 - 2.9e-06 27.8 0.0 0.1 13.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CBY22554.1 - 1.1e-05 25.8 0.0 0.082 13.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CBY22554.1 - 2.3e-05 24.4 0.0 0.035 14.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 CBY22554.1 - 3.1e-05 24.1 0.0 0.27 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CBY22554.1 - 5e-05 23.3 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 NACHT domain PduV-EutP PF10662.9 CBY22554.1 - 6.7e-05 22.7 0.0 0.052 13.3 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CBY22554.1 - 6.9e-05 23.1 0.0 0.44 10.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CBY22554.1 - 7.9e-05 22.7 1.1 0.011 15.7 0.0 3.1 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 CBY22554.1 - 8.8e-05 22.3 0.0 0.056 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CBY22554.1 - 9.6e-05 22.4 0.0 0.15 12.2 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY22554.1 - 0.00013 22.4 0.0 0.85 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CBY22554.1 - 0.00016 21.5 8.8 0.085 12.6 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CBY22554.1 - 0.00027 20.9 0.2 2.2 8.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CBY22554.1 - 0.00031 20.0 0.1 0.59 9.3 0.0 2.9 2 1 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 CBY22554.1 - 0.00048 19.9 0.1 1.4 8.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CBY22554.1 - 0.0008 19.8 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NTPase_1 PF03266.15 CBY22554.1 - 0.00085 19.3 0.1 0.82 9.6 0.0 3.2 4 0 0 4 4 3 1 NTPase Rad17 PF03215.15 CBY22554.1 - 0.0032 17.4 0.0 4.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain Dynamin_N PF00350.23 CBY22554.1 - 0.0034 17.5 0.9 1.3 9.0 0.0 3.5 2 1 1 3 3 3 1 Dynamin family Zeta_toxin PF06414.12 CBY22554.1 - 0.0035 16.7 0.0 0.37 10.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_27 PF13514.6 CBY22554.1 - 0.0045 16.6 0.3 1.5 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 CBY22554.1 - 0.0052 16.8 0.2 4 7.5 0.0 2.7 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CBY22554.1 - 0.0074 16.5 0.0 4.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 CBY22554.1 - 0.0094 16.4 0.0 3.5 8.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CBY22554.1 - 0.017 14.7 0.2 7.3 6.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 CBY22554.1 - 0.021 14.4 0.1 2.9 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 CBY22554.1 - 0.023 13.9 1.3 9.5 5.3 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 MukB PF04310.12 CBY22554.1 - 0.024 14.4 0.4 2.8 7.7 0.0 2.6 3 0 0 3 3 2 0 MukB N-terminal Septin PF00735.18 CBY22554.1 - 0.035 13.4 0.0 3 7.1 0.0 2.5 2 0 0 2 2 2 0 Septin ATP-synt_ab PF00006.25 CBY22554.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 CBY22554.1 - 0.036 13.7 0.1 5.8 6.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 CBY22554.1 - 0.042 13.6 0.0 0.4 10.4 0.0 2.4 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase DUF853 PF05872.12 CBY22554.1 - 0.054 12.1 1.1 0.12 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) G-alpha PF00503.20 CBY22554.1 - 0.072 12.2 5.4 9.4 5.3 0.0 3.0 2 1 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.13 CBY22554.1 - 0.074 12.2 0.1 13 4.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CBY22554.1 - 0.075 12.5 0.0 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Arf PF00025.21 CBY22554.1 - 0.093 12.2 2.4 11 5.5 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family MobB PF03205.14 CBY22554.1 - 0.098 12.6 1.0 8.4 6.3 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 CBY22554.1 - 0.098 12.4 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_13 PF13166.6 CBY22554.1 - 0.12 11.0 5.0 8.7 4.9 0.0 3.6 4 0 0 4 4 4 0 AAA domain DUF3584 PF12128.8 CBY22554.1 - 0.13 9.7 8.0 0.48 7.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DUF4164 PF13747.6 CBY22554.1 - 6.6 7.1 8.3 15 5.9 0.9 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) Pex14_N PF04695.13 CBY22556.1 - 2.5 8.8 7.7 4.9 7.8 7.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_12 PF13424.6 CBY22557.1 - 0.0038 17.5 0.0 0.6 10.4 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY22557.1 - 0.026 14.6 1.4 0.15 12.2 0.7 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PCM1_C PF15717.5 CBY22558.1 - 3.1e-06 26.2 0.3 3.1e-06 26.2 0.3 2.6 2 1 1 3 3 3 1 Pericentriolar material 1 C terminus Biotin_lipoyl PF00364.22 CBY22558.1 - 0.15 11.9 1.5 4 7.3 0.0 2.7 3 0 0 3 3 3 0 Biotin-requiring enzyme Leu_zip PF15294.6 CBY22558.1 - 6.7 6.1 24.7 0.2 11.2 3.9 2.8 2 1 0 2 2 2 0 Leucine zipper TB PF00683.17 CBY22559.1 - 1.5e-11 43.8 35.5 4.9e-07 29.4 8.4 4.3 3 0 0 3 3 3 3 TB domain EGF PF00008.27 CBY22559.1 - 6.4e-05 23.2 51.5 0.0039 17.5 8.1 5.8 5 0 0 5 5 5 4 EGF-like domain hEGF PF12661.7 CBY22559.1 - 0.0066 17.0 7.1 0.0066 17.0 7.1 6.4 6 0 0 6 6 6 3 Human growth factor-like EGF Chordopox_G2 PF05796.12 CBY22559.1 - 0.052 13.0 0.1 0.078 12.4 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus protein G2 TB PF00683.17 CBY22560.1 - 0.0038 16.9 1.8 0.0038 16.9 1.8 2.2 2 0 0 2 2 2 1 TB domain THRAP3_BCLAF1 PF15440.6 CBY22560.1 - 0.092 11.8 10.8 0.13 11.2 10.8 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Trypsin PF00089.26 CBY22561.1 - 6.2e-35 121.0 0.0 5.2e-24 85.3 0.0 2.2 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CBY22561.1 - 0.05 14.5 0.0 0.083 13.8 0.0 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain Toxin_2 PF00451.19 CBY22561.1 - 3.7 7.9 7.8 17 5.8 1.1 2.7 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 Homeodomain PF00046.29 CBY22562.1 - 1.2e-20 73.1 3.0 1.2e-20 73.1 3.0 2.2 1 1 1 2 2 2 1 Homeodomain Homez PF11569.8 CBY22562.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 CBY22562.1 - 0.07 13.0 0.1 0.22 11.4 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain Trypsin PF00089.26 CBY22564.1 - 2.8e-59 200.6 2.2 5.1e-59 199.8 2.2 1.5 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 CBY22564.1 - 1.4e-17 64.1 1.3 6.8e-08 32.8 0.1 2.5 2 0 0 2 2 2 2 CUB domain Trypsin_2 PF13365.6 CBY22564.1 - 0.079 13.9 0.0 0.24 12.3 0.0 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY22564.1 - 0.14 12.5 0.5 0.69 10.3 0.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) RRM_1 PF00076.22 CBY22565.1 - 1.5e-26 92.0 0.0 5.1e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY22565.1 - 0.0083 16.1 0.3 0.029 14.4 0.2 1.9 3 0 0 3 3 3 1 RNA binding motif RraB PF06877.11 CBY22565.1 - 0.039 14.7 0.1 0.1 13.4 0.1 1.6 1 0 0 1 1 1 0 Regulator of ribonuclease activity B Fzo_mitofusin PF04799.13 CBY22567.1 - 2.4 7.7 5.6 27 4.3 0.2 2.9 3 0 0 3 3 3 0 fzo-like conserved region rve PF00665.26 CBY22568.1 - 4.7e-09 36.5 0.0 3.6e-07 30.4 0.0 2.4 1 1 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY22568.1 - 0.0022 18.1 0.4 0.0045 17.1 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF4988 PF16378.5 CBY22568.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Peptidase_C48 PF02902.19 CBY22569.1 - 1.9e-06 27.9 6.7 0.00081 19.3 0.5 3.1 3 0 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 CBY22570.1 - 1.7e-06 28.0 6.5 0.00081 19.3 0.5 3.1 3 0 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain Pkinase PF00069.25 CBY22571.1 - 1.1e-56 192.2 0.0 1.7e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22571.1 - 1.4e-24 86.8 0.2 2.8e-24 85.8 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBY22571.1 - 3.7e-05 23.8 0.1 0.0029 17.6 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY22571.1 - 0.00081 19.0 1.0 0.0015 18.1 1.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 CBY22571.1 - 0.018 14.6 2.7 0.088 12.3 0.1 2.3 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.14 CBY22571.1 - 0.036 13.4 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY22571.1 - 0.06 12.6 0.0 0.26 10.6 0.0 1.8 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.22 CBY22571.1 - 0.18 11.4 5.3 0.044 13.4 0.5 2.3 3 1 0 3 3 3 0 RIO1 family Requiem_N PF14051.6 CBY22571.1 - 0.27 11.5 2.1 1.6 9.0 0.3 2.9 3 0 0 3 3 3 0 N-terminal domain of DPF2/REQ. Glycos_transf_2 PF00535.26 CBY22572.1 - 2e-32 112.3 0.0 3.5e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY22572.1 - 1.3e-29 103.0 4.4 2.6e-29 102.1 4.4 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 CBY22572.1 - 4e-06 26.9 0.0 1e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CBY22572.1 - 6.9e-05 22.4 0.1 0.00016 21.3 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY22572.1 - 0.0033 17.0 0.0 0.0086 15.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Keratin PF02422.16 CBY22572.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Keratin zf-RING_11 PF17123.5 CBY22572.1 - 4.4 7.1 8.4 45 3.9 0.1 3.5 3 0 0 3 3 3 0 RING-like zinc finger WD40 PF00400.32 CBY22573.1 - 3.1e-20 72.1 0.2 1.7e-06 28.6 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF3337 PF11816.8 CBY22573.1 - 3.2e-18 66.2 0.2 5.1e-18 65.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) ANAPC4_WD40 PF12894.7 CBY22573.1 - 0.0001 22.5 0.1 0.055 13.8 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY22573.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 CBY22573.1 - 0.022 13.7 0.0 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M14 PF00246.24 CBY22574.1 - 3.4e-12 46.8 0.2 2.3e-11 44.0 0.2 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CBY22574.1 - 0.13 11.4 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Pepdidase_M14_N PF18027.1 CBY22575.1 - 2.9e-16 59.8 0.5 4.3e-16 59.2 0.5 1.2 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain PAS_7 PF12860.7 CBY22575.1 - 0.091 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold ESCRT-II PF05871.12 CBY22576.1 - 2.2e-37 128.4 0.1 2.9e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit FAINT PF04385.15 CBY22576.1 - 0.021 14.9 0.0 0.039 14.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function, DUF529 SMC_N PF02463.19 CBY22577.1 - 2e-56 190.9 39.9 8.5e-55 185.6 39.9 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBY22577.1 - 4.2e-22 78.7 0.0 1.8e-21 76.6 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBY22577.1 - 1.7e-12 47.8 0.1 1e-08 35.4 0.5 3.7 5 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBY22577.1 - 3.4e-10 40.8 25.6 3.4e-10 40.8 25.6 7.7 2 2 3 5 5 2 1 AAA domain AAA_15 PF13175.6 CBY22577.1 - 5.1e-08 33.0 29.2 5.1e-08 33.0 29.2 4.4 2 2 2 4 4 1 1 AAA ATPase domain AAA_29 PF13555.6 CBY22577.1 - 7.1e-07 28.9 0.0 1.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1978 PF09321.10 CBY22577.1 - 0.0079 15.5 0.7 0.0079 15.5 0.7 7.3 3 2 4 7 7 3 2 Domain of unknown function (DUF1978) SbcCD_C PF13558.6 CBY22577.1 - 0.011 15.9 0.0 0.042 14.1 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 CBY22577.1 - 0.013 16.0 0.0 0.013 16.0 0.0 7.4 4 3 0 4 4 2 0 ABC transporter NPV_P10 PF05531.12 CBY22577.1 - 0.015 15.7 0.5 0.015 15.7 0.5 7.3 5 1 0 5 5 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 CBY22577.1 - 0.017 15.2 0.9 0.017 15.2 0.9 5.1 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 CBY22577.1 - 0.14 12.1 9.1 8 6.4 0.5 5.1 4 0 0 4 4 4 0 Apolipoprotein O AAA_5 PF07728.14 CBY22577.1 - 0.27 11.3 2.4 4.3 7.3 0.0 3.8 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 CBY22577.1 - 1.4 8.7 8.2 12 5.6 0.0 4.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein ketoacyl-synt PF00109.26 CBY22577.1 - 4.6 6.7 8.1 0.72 9.4 0.6 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Pkinase_Tyr PF07714.17 CBY22578.1 - 8.1e-91 303.9 0.0 1.1e-90 303.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY22578.1 - 2.9e-44 151.4 0.0 4.4e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gla PF00594.20 CBY22578.1 - 1.1e-15 57.5 10.8 2.3e-15 56.5 10.8 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Protocadherin PF08374.11 CBY22578.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DBR1 PF05011.13 CBY22579.1 - 1.9e-31 109.3 1.0 1.9e-31 109.3 1.0 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CBY22579.1 - 1.9e-08 35.1 0.8 4.2e-08 33.9 0.8 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CUB PF00431.20 CBY22582.1 - 3.3e-10 40.3 0.0 5.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 CUB domain BORCS7 PF16088.5 CBY22583.1 - 0.047 13.9 0.4 0.065 13.5 0.4 1.5 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 IRK_C PF17655.1 CBY22584.1 - 1.2e-34 119.5 0.0 1.8e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY22584.1 - 1.1e-33 116.0 7.0 1.5e-33 115.6 7.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY22584.1 - 0.4 10.7 16.2 0.3 11.1 12.7 2.1 1 1 1 2 2 2 0 Ion channel Virul_fac_BrkB PF03631.15 CBY22584.1 - 4 7.0 9.9 4.2 6.9 3.0 2.1 2 0 0 2 2 2 0 Virulence factor BrkB RCC1 PF00415.18 CBY22585.1 - 7.6e-58 192.9 9.1 4.7e-12 46.3 0.0 8.5 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY22585.1 - 4.3e-24 83.7 41.3 0.00012 21.7 1.2 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Ish1 PF10281.9 CBY22587.1 - 0.099 13.0 0.0 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein PPTA PF01239.22 CBY22588.1 - 6.5e-37 124.2 24.6 8.4e-09 34.9 0.3 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Spore_III_AB PF09548.10 CBY22588.1 - 0.014 15.6 0.5 0.24 11.5 0.1 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) GDP_Man_Dehyd PF16363.5 CBY22589.1 - 3.9e-55 187.6 0.0 4.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY22589.1 - 4.8e-52 176.8 0.0 5.9e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBY22589.1 - 4.4e-17 62.0 0.0 3.8e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CBY22589.1 - 8.5e-16 57.9 0.0 3.4e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CBY22589.1 - 5e-10 39.6 0.0 8.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CBY22589.1 - 2.2e-08 33.6 0.0 3.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CBY22589.1 - 6.2e-08 32.1 0.0 8.3e-07 28.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CBY22589.1 - 1.9e-07 31.2 0.0 4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CBY22589.1 - 2.3e-06 27.2 0.1 9.9e-06 25.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 CBY22589.1 - 4.1e-06 26.5 0.1 0.0036 16.9 0.0 2.4 2 1 0 2 2 2 2 NmrA-like family Sacchrp_dh_NADP PF03435.18 CBY22589.1 - 0.055 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 CBY22589.1 - 0.2 11.2 1.0 0.62 9.6 1.0 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LRR_8 PF13855.6 CBY22590.1 - 2.5e-09 36.7 6.0 1.9e-05 24.3 0.5 2.6 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY22590.1 - 2.8e-07 30.7 11.3 0.0028 18.0 0.7 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY22590.1 - 2.6e-06 27.2 8.0 0.49 11.2 1.0 4.8 4 1 0 4 4 4 2 Leucine Rich Repeat DEP PF00610.21 CBY22590.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LRR_9 PF14580.6 CBY22590.1 - 0.1 12.1 0.3 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 Leucine-rich repeat NPH3 PF03000.14 CBY22591.1 - 0.0058 16.3 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 NPH3 family FAM221 PF14753.6 CBY22592.1 - 2.3e-78 262.3 11.0 2.6e-78 262.1 11.0 1.0 1 0 0 1 1 1 1 Protein FAM221A/B DUF1184 PF06683.11 CBY22592.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) zf-H2C2_2 PF13465.6 CBY22592.1 - 2 9.0 10.2 2 9.0 2.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain GYF PF02213.16 CBY22594.1 - 0.00078 19.1 0.1 0.0018 17.9 0.1 1.7 1 0 0 1 1 1 1 GYF domain Cupin_8 PF13621.6 CBY22595.1 - 1.1e-20 74.5 0.1 1.5e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY22595.1 - 5.8e-07 29.3 0.0 5.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 CBY22595.1 - 0.005 17.3 0.0 0.028 14.9 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CBY22595.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain RRM_1 PF00076.22 CBY22596.1 - 0.055 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FragX_IP PF05994.11 CBY22599.1 - 0 1112.5 8.7 0 1112.5 8.7 1.5 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 CBY22599.1 - 8.8e-13 48.2 5.1 2.4e-12 46.8 5.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF1803 PF08820.10 CBY22599.1 - 0.035 14.1 0.5 0.2 11.7 0.5 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) Hemocyanin_N PF03722.14 CBY22599.1 - 8.4 6.9 12.7 1.8 9.1 0.4 4.0 4 0 0 4 4 4 0 Hemocyanin, all-alpha domain TM2 PF05154.16 CBY22600.1 - 1.4e-15 57.3 4.4 2.2e-15 56.7 4.4 1.2 1 0 0 1 1 1 1 TM2 domain Metallophos_2 PF12850.7 CBY22601.1 - 3.3e-16 59.9 0.0 3.7e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CBY22601.1 - 0.0065 17.0 0.0 0.018 15.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Taxilin PF09728.9 CBY22602.1 - 8.9e-07 28.4 6.4 8.9e-07 28.4 6.4 2.0 1 1 1 2 2 2 1 Myosin-like coiled-coil protein ExsD PF16806.5 CBY22602.1 - 8.7e-05 22.6 8.1 0.00012 22.2 8.1 1.1 1 0 0 1 1 1 1 Antiactivator protein ExsD BicD PF09730.9 CBY22602.1 - 0.0015 17.1 14.6 0.009 14.5 1.6 2.9 1 1 2 3 3 3 3 Microtubule-associated protein Bicaudal-D OmpH PF03938.14 CBY22602.1 - 0.015 15.7 15.3 0.016 15.5 4.8 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) LPP PF04728.13 CBY22602.1 - 0.018 15.4 12.9 0.031 14.7 0.1 3.4 3 1 1 4 4 3 0 Lipoprotein leucine-zipper FlgN PF05130.12 CBY22602.1 - 0.041 14.4 10.3 0.27 11.7 5.8 2.1 2 0 0 2 2 2 0 FlgN protein ABC_tran_Xtn PF12848.7 CBY22602.1 - 0.041 13.9 2.8 0.081 13.0 0.7 2.3 2 0 0 2 2 2 0 ABC transporter COG2 PF06148.11 CBY22602.1 - 0.049 13.7 11.1 0.095 12.8 2.3 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Fez1 PF06818.15 CBY22602.1 - 0.055 13.9 13.2 0.074 13.5 13.2 1.2 1 0 0 1 1 1 0 Fez1 Baculo_PEP_C PF04513.12 CBY22602.1 - 0.075 13.1 19.3 1.7 8.7 2.3 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 CBY22602.1 - 0.092 12.6 9.8 0.22 11.4 5.4 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 CBY22602.1 - 0.14 12.2 15.7 0.29 11.2 2.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 CBY22602.1 - 0.23 10.9 16.0 0.45 9.9 14.9 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3573 PF12097.8 CBY22602.1 - 0.25 10.1 7.0 0.32 9.8 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Atg14 PF10186.9 CBY22602.1 - 0.39 9.7 11.0 0.81 8.7 10.8 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 CBY22602.1 - 0.49 10.7 9.1 1.8 8.9 1.7 3.0 2 1 1 3 3 3 0 Tup N-terminal TPR_MLP1_2 PF07926.12 CBY22602.1 - 0.78 9.8 17.3 0.7 10.0 9.0 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 CBY22602.1 - 0.78 10.7 12.7 0.99 10.3 3.2 2.8 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Mod_r PF07200.13 CBY22602.1 - 0.82 9.8 15.3 0.064 13.4 6.9 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.11 CBY22602.1 - 0.87 9.9 8.1 4.3 7.7 2.6 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 CBY22602.1 - 1 10.0 12.4 0.38 11.4 1.2 3.6 1 1 3 4 4 4 0 SlyX Syntaxin_2 PF14523.6 CBY22602.1 - 1.2 9.5 19.8 0.48 10.8 8.9 2.9 1 1 1 2 2 2 0 Syntaxin-like protein ADIP PF11559.8 CBY22602.1 - 1.8 8.6 19.1 0.29 11.2 8.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 CBY22602.1 - 2 8.3 11.8 0.86 9.5 0.3 3.7 2 2 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 CBY22602.1 - 3.5 7.8 22.6 5 7.3 3.8 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 CBY22602.1 - 4.8 6.4 12.3 8.8 5.6 12.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ACCA PF03255.14 CBY22602.1 - 5.5 6.8 9.5 70 3.3 6.2 2.7 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Metallophos_2 PF12850.7 CBY22603.1 - 0.0059 16.8 0.0 0.0074 16.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain eIF-3c_N PF05470.12 CBY22604.1 - 1e-154 516.2 48.0 7.8e-154 513.2 42.4 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CBY22604.1 - 1.8e-12 47.7 0.2 7.5e-12 45.7 0.2 2.2 1 0 0 1 1 1 1 PCI domain DUF1132 PF06575.12 CBY22604.1 - 0.065 13.6 0.6 0.24 11.8 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) RPA_interact_N PF14766.6 CBY22605.1 - 1.6e-08 34.0 6.2 2.6e-08 33.3 6.2 1.3 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Cactin_mid PF10312.9 CBY22605.1 - 0.013 15.2 0.5 0.023 14.4 0.5 1.4 1 1 0 1 1 1 0 Conserved mid region of cactin RPA_interact_C PF14768.6 CBY22605.1 - 0.054 14.1 6.3 0.061 13.9 5.1 1.7 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Cse1 PF08506.10 CBY22606.1 - 3e-131 437.6 1.5 5.3e-131 436.8 0.4 1.9 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 CBY22606.1 - 2.2e-100 336.2 0.3 3.5e-100 335.6 0.3 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CBY22606.1 - 2.1e-11 43.6 0.9 3.3e-10 39.7 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CBY22606.1 - 1.4e-05 25.2 3.0 1.8 8.6 0.1 5.4 5 1 0 5 5 5 2 Exportin 1-like protein Cnd3 PF12719.7 CBY22606.1 - 0.0036 16.6 0.4 0.014 14.6 0.4 2.1 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CBY22606.1 - 0.036 14.5 6.9 3.2 8.2 0.0 5.0 6 1 0 6 6 6 0 HEAT repeats TAF6_C PF07571.13 CBY22606.1 - 0.13 12.6 0.1 4.4 7.7 0.0 3.2 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Adaptin_N PF01602.20 CBY22606.1 - 0.4 9.2 5.4 0.23 10.0 1.0 2.8 3 1 0 3 3 3 0 Adaptin N terminal region HEAT_EZ PF13513.6 CBY22606.1 - 0.54 10.8 11.3 1.5 9.4 0.0 5.2 5 1 0 5 5 5 0 HEAT-like repeat HEAT PF02985.22 CBY22606.1 - 0.65 10.4 8.3 9.1 6.8 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat BAT2_N PF07001.11 CBY22607.1 - 5.6 7.4 6.8 0.33 11.4 1.4 1.6 2 0 0 2 2 2 0 BAT2 N-terminus zf-TAZ PF02135.16 CBY22608.1 - 2.7e-07 30.9 17.3 2.7e-07 30.9 17.3 2.0 2 0 0 2 2 2 1 TAZ zinc finger HisK_N PF09385.10 CBY22608.1 - 0.055 13.4 1.1 0.1 12.5 1.1 1.4 1 0 0 1 1 1 0 Histidine kinase N terminal Oest_recep PF02159.15 CBY22609.1 - 0.0042 17.6 6.7 0.0079 16.7 6.7 1.4 1 0 0 1 1 1 1 Oestrogen receptor Zona_pellucida PF00100.23 CBY22610.1 - 4.9e-17 62.6 0.3 5.5e-17 62.4 0.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain HLH PF00010.26 CBY22611.1 - 9.1e-16 57.6 0.1 2.5e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Clostridium_P47 PF06597.11 CBY22611.1 - 0.062 12.0 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Clostridium P-47 protein Cnn_1N PF07989.11 CBY22611.1 - 0.062 13.5 1.1 0.18 12.0 1.1 1.8 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF2203 PF09969.9 CBY22611.1 - 0.14 12.9 1.3 0.97 10.2 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.22 CBY22611.1 - 0.55 10.5 5.4 1 9.7 1.0 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TraS PF10624.9 CBY22612.1 - 0.12 12.2 0.5 0.2 11.5 0.5 1.4 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS ELFV_dehydrog_N PF02812.18 CBY22613.1 - 1.5e-58 196.3 0.0 3.3e-58 195.2 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 CBY22613.1 - 5.5e-47 160.5 0.2 3.4e-45 154.7 0.1 2.2 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CBY22613.1 - 0.17 9.4 0.0 0.23 8.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase PLAT PF01477.23 CBY22614.1 - 1.8e-275 896.0 70.3 5.1e-24 85.1 0.0 21.7 19 3 3 22 22 22 19 PLAT/LH2 domain ATS3 PF06232.11 CBY22614.1 - 4.1e-16 59.0 0.0 0.00075 19.4 0.0 10.1 12 0 0 12 12 12 3 Embryo-specific protein 3, (ATS3) adh_short PF00106.25 CBY22614.1 - 1.5e-12 47.4 0.3 2.7e-12 46.6 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY22614.1 - 5e-06 26.2 0.1 8.9e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY22614.1 - 2.6e-05 24.2 0.2 5.2e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 KR domain Trypan_PARP PF05887.11 CBY22614.1 - 0.82 9.7 6.4 1.6 8.7 6.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) 7tm_1 PF00001.21 CBY22615.1 - 0.0015 17.9 0.1 0.0015 17.9 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Colicin_im PF03857.13 CBY22615.1 - 0.014 15.3 0.3 0.03 14.3 0.3 1.5 1 0 0 1 1 1 0 Colicin immunity protein EGF_CA PF07645.15 CBY22616.1 - 1.2e-08 34.9 7.0 1.2e-08 34.9 7.0 2.0 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY22616.1 - 0.0021 18.2 3.9 0.0021 18.2 3.9 1.8 2 1 0 2 2 2 1 EGF domain EB PF01683.18 CBY22616.1 - 0.0035 17.6 6.6 0.0069 16.6 6.6 1.5 1 1 0 1 1 1 1 EB module FXa_inhibition PF14670.6 CBY22616.1 - 0.013 15.8 7.7 0.013 15.8 7.7 2.0 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY22616.1 - 0.023 15.0 10.9 0.042 14.2 7.9 2.6 1 1 2 3 3 3 0 EGF-like domain cEGF PF12662.7 CBY22616.1 - 0.062 13.2 0.4 0.062 13.2 0.4 3.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.7 CBY22616.1 - 0.086 13.5 4.2 0.086 13.5 4.2 2.5 2 1 1 3 3 3 0 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY22617.1 - 6.1e-12 45.6 8.7 6.1e-12 45.6 8.7 5.6 6 1 1 7 7 7 1 Coagulation Factor Xa inhibitory site Ephrin_rec_like PF07699.13 CBY22617.1 - 1.4e-06 28.0 4.6 1.4e-06 28.0 4.6 4.7 3 1 2 5 5 5 1 Putative ephrin-receptor like Sushi PF00084.20 CBY22617.1 - 2.7e-05 24.7 5.5 0.0018 18.8 0.5 5.3 6 0 0 6 6 6 3 Sushi repeat (SCR repeat) HYR PF02494.16 CBY22617.1 - 0.00057 20.2 0.2 0.076 13.3 0.1 2.8 2 0 0 2 2 2 1 HYR domain EGF PF00008.27 CBY22617.1 - 0.017 15.5 7.7 0.017 15.5 7.7 5.5 5 0 0 5 5 5 0 EGF-like domain cEGF PF12662.7 CBY22617.1 - 0.024 14.6 2.8 0.024 14.6 2.8 5.6 5 0 0 5 5 5 0 Complement Clr-like EGF-like DEAD PF00270.29 CBY22619.1 - 1e-29 103.6 0.2 1.8e-29 102.7 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY22619.1 - 8.1e-26 90.5 0.3 2.2e-25 89.2 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY22619.1 - 0.00077 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBY22619.1 - 0.032 13.9 0.2 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF4674 PF15719.5 CBY22619.1 - 0.1 12.7 0.2 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) TYW3 PF02676.14 CBY22620.1 - 1.4e-33 116.0 0.0 1.7e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 TRAPP PF04051.16 CBY22621.1 - 3.8e-32 111.0 0.1 4.4e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PIGA PF08288.12 CBY22622.1 - 5.4e-25 87.8 0.1 2.2e-24 85.9 0.1 2.1 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 CBY22622.1 - 2.9e-23 82.3 0.0 5e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY22622.1 - 3.4e-22 79.2 0.0 5.7e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CBY22622.1 - 2.9e-19 69.8 0.0 5.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CBY22622.1 - 1.2e-10 42.1 0.0 1.7e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Phage-tail_2 PF09096.10 CBY22623.1 - 0.02 14.9 0.3 0.037 14.0 0.3 1.4 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 BMC PF00936.19 CBY22623.1 - 0.22 11.5 0.0 0.49 10.4 0.0 1.6 1 0 0 1 1 1 0 BMC domain Rdx PF10262.9 CBY22624.1 - 4.2e-05 23.7 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Rdx family DEAD PF00270.29 CBY22626.1 - 4e-13 49.5 0.0 7.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY22626.1 - 4.8e-10 39.8 0.0 1.3e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CBY22626.1 - 2.1e-09 37.6 0.0 4.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) TUDOR PF00567.24 CBY22626.1 - 2.3e-08 34.1 0.0 6.8e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Tudor domain AAA_22 PF13401.6 CBY22626.1 - 2.2e-06 28.0 0.0 6.8e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY22626.1 - 0.00014 22.2 0.0 0.00034 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CBY22626.1 - 0.00088 19.0 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ResIII PF04851.15 CBY22626.1 - 0.0043 17.1 0.0 0.018 15.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CBY22626.1 - 0.0064 16.9 0.0 0.021 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CBY22626.1 - 0.0075 16.8 0.0 0.02 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBY22626.1 - 0.0086 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 CBY22626.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 CBY22626.1 - 0.036 13.1 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 CBY22626.1 - 0.047 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBY22626.1 - 0.048 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 CBY22626.1 - 0.051 13.3 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain SNase PF00565.17 CBY22626.1 - 0.083 13.4 0.0 0.36 11.3 0.0 2.1 1 0 0 1 1 1 0 Staphylococcal nuclease homologue FtsK_SpoIIIE PF01580.18 CBY22626.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CBY22626.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 CBY22626.1 - 0.18 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TB2_DP1_HVA22 PF03134.19 CBY22627.1 - 8.2e-14 51.3 3.0 1.3e-13 50.6 3.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Exonuc_X-T_C PF08411.10 CBY22627.1 - 0.035 13.2 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Exonuclease C-terminal 2-Hacid_dh_C PF02826.19 CBY22628.1 - 5.9e-20 71.4 0.0 1.1e-19 70.5 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain T3SS_NleG PF06416.12 CBY22629.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Effector protein NleG Myosin_head PF00063.21 CBY22630.1 - 4.7e-82 276.3 1.0 7.7e-70 235.9 0.4 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 CBY22630.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY22630.1 - 0.028 13.9 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CBY22630.1 - 0.044 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CBY22630.1 - 0.045 13.8 0.3 0.36 10.9 0.1 2.2 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CBY22630.1 - 0.057 12.3 0.1 0.09 11.7 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 CBY22630.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBY22630.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CBY22630.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Myosin_head PF00063.21 CBY22631.1 - 1.5e-112 377.1 0.0 1.5e-112 377.1 0.0 3.5 3 2 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY22631.1 - 1.7e-110 370.6 232.3 1.4e-74 251.6 158.7 3.1 1 1 1 2 2 2 2 Myosin tail MtrB PF05440.12 CBY22631.1 - 0.88 10.0 8.3 30 5.1 0.1 5.6 4 1 1 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B Kinesin PF00225.23 CBY22632.1 - 2.2e-106 355.6 0.2 2.2e-106 355.6 0.2 3.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY22632.1 - 3.6e-22 78.9 0.0 3.6e-22 78.9 0.0 2.7 2 1 0 2 2 2 1 Microtubule binding TMC PF07810.13 CBY22633.1 - 4.3e-25 88.5 1.2 4.3e-25 88.5 1.2 2.3 2 0 0 2 2 2 1 TMC domain Pox_A14 PF05767.12 CBY22633.1 - 1.1 9.5 13.3 3.4 7.9 2.2 3.5 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Yip1 PF04893.17 CBY22633.1 - 1.3 8.7 19.9 1e+02 2.6 11.1 4.1 1 1 1 2 2 2 0 Yip1 domain FA_desaturase PF00487.24 CBY22633.1 - 2.9 7.7 9.1 0.34 10.7 2.9 2.5 2 1 0 2 2 2 0 Fatty acid desaturase Snf7 PF03357.21 CBY22634.1 - 3.6e-54 183.0 13.5 4.3e-54 182.7 13.5 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_3 PF13758.6 CBY22634.1 - 0.0058 16.7 2.4 0.028 14.5 0.4 2.2 2 0 0 2 2 2 1 Prefoldin subunit Spc7 PF08317.11 CBY22634.1 - 0.0099 14.8 7.0 0.014 14.3 7.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein NAGLU_C PF12972.7 CBY22634.1 - 0.037 13.6 2.1 0.045 13.3 2.1 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain DUF1319 PF07028.11 CBY22634.1 - 0.091 13.0 1.2 0.23 11.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) Lectin_N PF03954.14 CBY22634.1 - 0.14 11.9 1.7 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain GTP-bdg_M PF16360.5 CBY22634.1 - 0.15 12.6 2.9 2.3 8.9 0.1 2.5 1 1 0 2 2 2 0 GTP-binding GTPase Middle Region DUF2229 PF09989.9 CBY22634.1 - 0.17 11.5 1.2 0.21 11.2 1.2 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PhaP_Bmeg PF09602.10 CBY22634.1 - 0.21 11.5 6.5 0.19 11.6 2.7 2.1 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Glutaredoxin PF00462.24 CBY22634.1 - 0.3 11.3 0.3 0.3 11.3 0.3 1.8 2 0 0 2 2 1 0 Glutaredoxin ABC_tran_CTD PF16326.5 CBY22634.1 - 0.48 10.7 6.4 7.8 6.8 0.1 2.8 2 2 0 2 2 2 0 ABC transporter C-terminal domain Atg14 PF10186.9 CBY22634.1 - 0.68 9.0 4.9 0.87 8.6 4.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4337 PF14235.6 CBY22634.1 - 2.2 8.4 9.7 0.61 10.2 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) NPV_P10 PF05531.12 CBY22634.1 - 4 8.0 10.4 15 6.1 5.7 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 CBY22634.1 - 6.2 6.9 12.0 2.9 7.9 7.4 2.1 1 1 2 3 3 3 0 FlxA-like protein DUF4407 PF14362.6 CBY22634.1 - 8.8 5.6 8.3 16 4.7 8.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UCH PF00443.29 CBY22635.1 - 2.2e-25 89.6 0.5 2.8e-25 89.3 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY22635.1 - 3.2e-10 40.1 3.7 1.2e-08 35.0 3.7 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Josephin PF02099.17 CBY22635.1 - 0.034 14.3 0.1 0.07 13.2 0.1 1.5 1 0 0 1 1 1 0 Josephin GRASP55_65 PF04495.14 CBY22635.1 - 0.082 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Glyco_hydro_18 PF00704.28 CBY22637.1 - 9e-23 81.5 0.0 1.1e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FH2 PF02181.23 CBY22638.1 - 4.4e-95 319.0 0.4 4.4e-95 319.0 0.4 2.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CBY22638.1 - 7.4e-32 110.5 7.5 2e-31 109.1 7.5 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CBY22638.1 - 1.1e-19 70.8 13.7 9.7e-13 48.1 0.2 3.7 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Cyclin PF08613.11 CBY22638.1 - 1e-05 26.0 0.9 1.7e-05 25.3 0.0 1.9 2 0 0 2 2 1 1 Cyclin Cyclin_N PF00134.23 CBY22638.1 - 0.0021 17.8 0.1 0.0067 16.2 0.1 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4349 PF14257.6 CBY22638.1 - 0.03 13.8 1.2 0.074 12.5 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3619 PF12279.8 CBY22638.1 - 0.26 11.6 2.6 0.95 9.8 2.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) BBP1_C PF15272.6 CBY22638.1 - 0.93 9.3 12.5 0.018 14.9 2.0 2.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF4407 PF14362.6 CBY22638.1 - 2.4 7.4 14.9 1.4 8.2 7.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) RSS_P20 PF11757.8 CBY22638.1 - 6 7.4 8.7 9.1 6.8 0.2 3.6 4 0 0 4 4 4 0 Suppressor of RNA silencing P21-like N-terminal domain DUF4665 PF15679.5 CBY22638.1 - 9.1 7.0 10.8 39 5.0 2.9 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) RabGAP-TBC PF00566.18 CBY22639.1 - 3.3e-44 151.1 1.0 4.8e-44 150.6 1.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF499 PF04465.12 CBY22639.1 - 0.085 10.6 0.0 0.12 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) zf-H2C2_2 PF13465.6 CBY22640.1 - 0.012 16.0 0.7 0.012 16.0 0.7 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY22640.1 - 0.057 14.3 15.8 1.3 10.1 3.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Desulfoferrod_N PF06397.12 CBY22640.1 - 2.2 8.0 4.3 22 4.8 0.5 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain BTB PF00651.31 CBY22641.1 - 4.3e-19 68.8 0.0 1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY22641.1 - 2.6e-10 40.3 0.3 2.8e-09 37.0 0.3 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Gal-3-0_sulfotr PF06990.11 CBY22642.1 - 3.6e-28 98.6 2.8 1.2e-27 96.8 2.8 1.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Thioredoxin_8 PF13905.6 CBY22642.1 - 0.35 11.2 2.2 0.9 9.9 0.0 2.7 2 1 1 3 3 3 0 Thioredoxin-like SNF PF00209.18 CBY22644.1 - 1.3e-166 555.4 40.7 1.5e-166 555.2 40.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family UPF0261 PF06792.11 CBY22647.1 - 0.22 10.4 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) DUF728 PF05304.12 CBY22648.1 - 0.23 11.3 3.9 0.87 9.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF728) IRK_C PF17655.1 CBY22649.1 - 2.7e-60 202.9 0.0 3.9e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY22649.1 - 9.3e-52 174.6 3.7 1.3e-51 174.1 3.7 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain dCache_1 PF02743.18 CBY22650.1 - 0.0011 18.8 0.1 0.0074 16.1 0.0 2.1 2 0 0 2 2 2 1 Cache domain DIOX_N PF14226.6 CBY22652.1 - 3.3e-09 37.5 0.0 4.3e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Neur_chan_memb PF02932.16 CBY22653.1 - 0.00021 21.5 0.0 0.00021 21.5 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 CBY22654.1 - 7.6e-29 101.5 12.3 9.7e-29 101.1 12.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY22654.1 - 3.2e-21 75.8 4.4 2.6e-20 72.8 4.4 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain PROCT PF08084.11 CBY22655.1 - 0.046 13.7 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 PROCT (NUC072) domain DUF1639 PF07797.14 CBY22657.1 - 0.06 13.3 0.2 0.18 11.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Ldl_recept_a PF00057.18 CBY22658.1 - 1.9e-14 53.6 27.8 7.7e-08 32.4 7.9 2.9 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A CUB PF00431.20 CBY22658.1 - 8.6e-09 35.7 0.0 6.6e-08 32.9 0.1 2.2 2 0 0 2 2 2 1 CUB domain CUB PF00431.20 CBY22659.1 - 9.7e-44 148.2 0.0 4.8e-15 55.8 0.0 4.7 4 0 0 4 4 4 4 CUB domain MAM PF00629.23 CBY22659.1 - 9.8e-26 90.6 0.0 1.9e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Trypsin PF00089.26 CBY22659.1 - 5.7e-22 78.6 0.7 1.1e-21 77.7 0.7 1.5 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 CBY22659.1 - 3.1e-06 27.3 25.1 0.00031 20.9 10.8 3.0 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Trypsin PF00089.26 CBY22660.1 - 4.3e-22 79.0 0.5 7.3e-22 78.3 0.0 1.6 2 0 0 2 2 2 1 Trypsin Ldl_recept_a PF00057.18 CBY22660.1 - 9.4e-08 32.2 36.5 0.0002 21.5 9.9 3.2 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SRCR_2 PF15494.6 CBY22660.1 - 1.3e-06 28.8 0.9 3e-06 27.7 0.9 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 CBY22660.1 - 3.3e-05 24.3 0.0 9.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY22660.1 - 0.1 13.5 0.0 0.24 12.3 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain Kelch_1 PF01344.25 CBY22661.1 - 4.2e-14 51.9 12.2 0.00026 20.5 1.1 6.4 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 CBY22661.1 - 6.1e-12 45.3 4.2 0.00013 21.8 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 CBY22661.1 - 7.4e-07 29.2 15.0 0.0092 16.2 0.0 6.1 4 2 2 6 6 6 1 Kelch motif Kelch_4 PF13418.6 CBY22661.1 - 9.2e-05 22.4 12.8 0.001 19.0 0.0 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY22661.1 - 0.00017 21.4 7.8 22 5.2 0.1 5.8 5 1 1 6 6 6 0 Kelch motif Kelch_3 PF13415.6 CBY22661.1 - 0.00022 21.4 9.4 2.9 8.3 0.0 6.1 6 0 0 6 6 6 1 Galactose oxidase, central domain Rnk_N PF14760.6 CBY22661.1 - 0.068 13.7 0.5 3.1 8.4 0.0 2.7 2 0 0 2 2 2 0 Rnk N-terminus Lebercilin PF15619.6 CBY22661.1 - 0.089 12.4 7.8 0.15 11.7 7.8 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.12 CBY22661.1 - 0.1 12.9 4.5 0.72 10.2 1.9 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 CBY22661.1 - 0.7 10.1 5.5 0.44 10.7 1.1 2.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 CBY22661.1 - 1.1 8.8 4.0 1.5 8.3 4.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-LITAF-like PF10601.9 CBY22662.1 - 0.0026 18.0 14.0 0.0039 17.4 14.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain HMG_box PF00505.19 CBY22663.1 - 1.1e-16 61.0 4.8 5.6e-16 58.7 4.8 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY22663.1 - 3e-13 50.2 1.4 4.2e-13 49.7 1.4 1.2 1 0 0 1 1 1 1 HMG-box domain Zip PF02535.22 CBY22665.1 - 8.6e-20 71.2 10.8 3.6e-16 59.3 2.2 3.0 1 1 0 2 2 2 2 ZIP Zinc transporter DoxX_2 PF13564.6 CBY22665.1 - 0.0054 16.8 0.8 0.028 14.5 0.1 2.5 2 0 0 2 2 2 1 DoxX-like family BPD_transp_2 PF02653.16 CBY22665.1 - 0.016 14.4 0.4 0.016 14.4 0.4 2.6 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component LapA_dom PF06305.11 CBY22665.1 - 0.88 9.4 7.1 3.2 7.7 0.0 4.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Gaa1 PF04114.14 CBY22665.1 - 5.5 5.9 8.0 2.9 6.8 1.8 2.3 3 0 0 3 3 3 0 Gaa1-like, GPI transamidase component NTF2 PF02136.20 CBY22666.1 - 4.7e-35 120.8 0.1 5.2e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 CBY22666.1 - 0.015 15.7 0.0 0.017 15.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) P3A PF08727.11 CBY22666.1 - 0.17 11.3 0.3 0.23 10.9 0.3 1.2 1 0 0 1 1 1 0 Poliovirus 3A protein like Vac_ImportDeg PF09783.9 CBY22666.1 - 0.21 11.4 0.4 4.5 7.1 0.0 2.0 1 1 1 2 2 2 0 Vacuolar import and degradation protein YL1 PF05764.13 CBY22667.1 - 1.9e-06 28.2 2.0 3.3e-06 27.4 2.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 CBY22667.1 - 0.00067 19.4 0.3 0.0071 16.1 0.3 2.2 1 1 0 1 1 1 1 YL1 nuclear protein C-terminal domain YL1 PF05764.13 CBY22668.1 - 9.6e-19 68.5 26.2 2.7e-18 67.0 26.2 1.6 1 1 0 1 1 1 1 YL1 nuclear protein Mem_trans PF03547.18 CBY22668.1 - 0.93 7.8 5.4 1.1 7.6 5.4 1.1 1 0 0 1 1 1 0 Membrane transport protein RR_TM4-6 PF06459.12 CBY22668.1 - 1.6 8.5 15.5 1.9 8.2 15.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CBY22668.1 - 3.1 4.8 9.2 3.4 4.7 9.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 CBY22668.1 - 3.4 5.8 18.3 3.6 5.8 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein GYF PF02213.16 CBY22670.1 - 2.5e-16 59.1 0.7 5.3e-16 58.0 0.7 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CBY22670.1 - 0.01 15.6 0.0 0.038 13.8 0.0 2.1 1 0 0 1 1 1 0 GYF domain 2 Exo70 PF03081.15 CBY22671.1 - 1.2e-60 205.6 0.8 1.2e-60 205.6 0.8 1.5 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Vps52 PF04129.12 CBY22671.1 - 0.037 12.8 1.6 0.17 10.6 0.2 2.2 2 0 0 2 2 2 0 Vps52 / Sac2 family EMP70 PF02990.16 CBY22672.1 - 7e-203 675.0 11.5 7e-203 675.0 11.5 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 Rap_GAP PF02145.15 CBY22673.1 - 0.00062 19.4 0.0 0.39 10.2 0.0 3.2 3 0 0 3 3 3 2 Rap/ran-GAP EF-hand_7 PF13499.6 CBY22674.1 - 4.3e-12 46.3 2.7 5.9e-06 26.6 0.3 2.7 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY22674.1 - 1.3e-11 43.5 0.5 9.4e-06 25.2 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY22674.1 - 5.3e-10 38.1 1.3 7.7e-05 22.0 0.4 3.2 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CBY22674.1 - 5.1e-06 25.7 0.7 0.021 14.3 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY22674.1 - 0.0044 16.8 0.8 3.6 7.5 0.3 3.4 2 1 2 4 4 4 2 EF-hand domain pair RST PF12174.8 CBY22674.1 - 0.013 15.4 0.5 0.032 14.1 0.2 1.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain SPARC_Ca_bdg PF10591.9 CBY22674.1 - 0.013 15.8 0.6 2.6 8.4 0.2 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CBY22674.1 - 0.038 14.3 0.0 0.3 11.5 0.0 2.4 3 1 0 3 3 3 0 EF-hand domain Collagen PF01391.18 CBY22675.1 - 3.1e-15 55.7 64.5 5.6e-09 35.6 30.2 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF2630 PF10944.8 CBY22675.1 - 0.0022 18.4 0.1 0.0028 18.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2630) K-box PF01486.17 CBY22675.1 - 0.048 13.8 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 K-box region FapA PF03961.13 CBY22676.1 - 0.0022 16.7 5.1 0.0043 15.7 5.1 1.4 1 0 0 1 1 1 1 Flagellar Assembly Protein A Adaptin_binding PF10199.9 CBY22676.1 - 0.0055 17.3 0.0 0.0093 16.6 0.0 1.5 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Imm64 PF15600.6 CBY22676.1 - 0.045 13.4 1.4 0.077 12.7 1.4 1.3 1 0 0 1 1 1 0 Immunity protein 64 DUF4446 PF14584.6 CBY22676.1 - 0.16 11.9 9.7 0.9 9.5 6.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Syntaxin_2 PF14523.6 CBY22676.1 - 0.41 11.0 8.0 0.12 12.8 4.9 1.7 2 0 0 2 2 2 0 Syntaxin-like protein GAS PF13851.6 CBY22676.1 - 0.43 9.9 15.3 0.035 13.5 10.6 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Synaptobrevin PF00957.21 CBY22676.1 - 0.73 9.7 13.0 0.22 11.3 9.1 2.0 2 0 0 2 2 2 0 Synaptobrevin Fib_alpha PF08702.10 CBY22676.1 - 1.6 8.9 10.4 0.31 11.2 6.8 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CBY22676.1 - 2.7 8.0 7.8 3.3 7.8 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2681 PF10883.8 CBY22676.1 - 6.1 7.3 9.5 1.5 9.3 0.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Val_tRNA-synt_C PF10458.9 CBY22676.1 - 9.4 6.6 10.9 1.6 9.1 6.3 2.2 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm CutA1 PF03091.15 CBY22677.1 - 8.1e-37 125.1 0.0 9e-37 124.9 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Carn_acyltransf PF00755.20 CBY22680.1 - 1.7e-157 525.6 0.0 2.1e-157 525.3 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 CBY22680.1 - 1.7e-32 112.8 30.4 1.4e-29 103.1 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY22680.1 - 4.6 6.0 12.0 1.3e+02 1.2 11.4 2.8 1 1 1 2 2 2 0 MFS_1 like family WASH_WAHD PF11945.8 CBY22681.1 - 0.0065 16.0 2.4 3.2 7.2 0.1 3.2 3 0 0 3 3 3 1 WAHD domain of WASH complex DUF948 PF06103.11 CBY22681.1 - 0.018 15.3 3.3 0.39 11.0 0.6 3.2 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Helo_like_N PF17111.5 CBY22681.1 - 0.023 14.0 1.0 0.023 14.0 1.0 3.2 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins BCAS2 PF05700.11 CBY22681.1 - 0.023 14.4 1.6 0.023 14.4 1.6 2.7 1 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF16 PF01519.16 CBY22681.1 - 0.027 15.0 24.6 0.1 13.1 0.4 4.1 1 1 3 4 4 4 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 CBY22681.1 - 0.07 13.6 11.1 4.4 7.8 0.0 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 CBY22681.1 - 0.24 11.8 13.8 1.6 9.1 0.1 5.5 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) LIF_OSM PF01291.17 CBY22681.1 - 0.24 11.5 4.2 0.39 10.8 1.1 2.6 1 1 1 2 2 2 0 LIF / OSM family YtxH PF12732.7 CBY22681.1 - 0.26 11.8 7.5 0.9 10.1 0.5 3.4 2 1 0 2 2 2 0 YtxH-like protein Prominin PF05478.11 CBY22681.1 - 0.46 8.4 12.7 0.032 12.2 4.1 2.0 1 1 1 2 2 2 0 Prominin DUF1664 PF07889.12 CBY22681.1 - 0.47 10.5 14.3 0.27 11.3 0.6 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF2205 PF10224.9 CBY22681.1 - 1.2 9.2 18.2 1.2 9.2 1.4 4.4 3 1 1 4 4 4 0 Short coiled-coil protein Prefoldin PF02996.17 CBY22681.1 - 2.3 8.2 16.1 2.2 8.2 0.7 4.4 4 1 1 5 5 5 0 Prefoldin subunit FUSC PF04632.12 CBY22681.1 - 3.7 6.0 6.9 18 3.7 6.9 1.9 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF2316 PF10078.9 CBY22681.1 - 6.5 7.1 9.1 0.5 10.6 1.1 3.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) CLZ PF16526.5 CBY22681.1 - 6.6 7.2 25.3 1.4 9.3 1.5 5.1 2 1 4 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MCU PF04678.13 CBY22681.1 - 8.9 6.4 11.8 0.49 10.5 1.0 3.0 1 1 2 3 3 3 0 Mitochondrial calcium uniporter LRR_8 PF13855.6 CBY22682.1 - 4.4e-25 87.2 13.3 6e-09 35.5 1.5 5.0 4 1 1 5 5 5 4 Leucine rich repeat LRR_5 PF13306.6 CBY22682.1 - 8.8e-17 61.3 1.8 2.5e-10 40.4 0.2 2.7 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY22682.1 - 1.3e-14 54.1 18.2 0.00012 22.3 2.2 5.9 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 CBY22682.1 - 2.7e-13 50.0 0.0 2e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 CBY22682.1 - 5.9e-10 39.6 0.4 2.7e-08 34.3 0.0 3.1 3 1 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 CBY22682.1 - 7.5e-07 29.1 0.2 1.6e-05 24.9 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 CBY22682.1 - 0.00022 21.3 0.1 0.075 13.2 0.0 3.2 2 1 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 CBY22682.1 - 0.0011 19.2 18.6 0.14 12.8 0.0 6.5 6 2 1 7 7 5 2 Leucine Rich Repeat V-set PF07686.17 CBY22682.1 - 0.0089 16.2 1.0 0.098 12.8 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRR_9 PF14580.6 CBY22682.1 - 0.011 15.3 2.8 1 8.8 0.9 2.6 1 1 1 2 2 2 0 Leucine-rich repeat Ig_6 PF18452.1 CBY22682.1 - 0.073 12.6 0.2 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin domain LRR_6 PF13516.6 CBY22682.1 - 0.14 12.3 14.9 3.4 8.0 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich repeat Phospholip_A2_1 PF00068.19 CBY22683.1 - 1.3e-14 54.6 9.6 1.3e-14 54.6 9.6 2.1 2 0 0 2 2 2 1 Phospholipase A2 Homeobox_KN PF05920.11 CBY22684.1 - 1.4e-15 56.9 0.9 5.9e-15 54.9 0.2 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CBY22684.1 - 2.8e-06 27.1 0.6 2.8e-06 27.1 0.6 1.8 2 0 0 2 2 2 1 Homeodomain Forkhead PF00250.18 CBY22685.1 - 1.7e-25 89.1 0.0 5.8e-25 87.4 0.0 1.9 2 0 0 2 2 2 1 Forkhead domain RR_TM4-6 PF06459.12 CBY22685.1 - 3 7.6 5.5 4.3 7.1 5.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CytochromB561_N PF09786.9 CBY22685.1 - 3.7 6.4 12.5 5 6.0 12.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal U3_assoc_6 PF08640.11 CBY22687.1 - 2.8e-15 56.1 5.3 6.6e-15 55.0 5.3 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 CBY22687.1 - 2.4e-06 27.9 0.7 0.024 15.4 0.1 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY22687.1 - 0.0001 22.7 0.3 0.0029 18.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY22687.1 - 0.004 17.4 0.2 0.39 11.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat VGPC1_C PF16799.5 CBY22687.1 - 0.04 13.9 0.0 0.16 12.0 0.0 2.1 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 HAT PF02184.16 CBY22687.1 - 0.063 13.2 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat NRDE-2 PF08424.10 CBY22687.1 - 1.9 7.5 7.8 2.7 7.0 3.5 2.1 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference SF3b1 PF08920.10 CBY22688.1 - 2.9e-39 134.2 3.7 2.9e-39 134.2 3.7 4.0 2 1 3 5 5 5 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CBY22688.1 - 2.5e-09 37.4 1.2 0.098 13.1 0.0 7.2 6 2 2 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 CBY22688.1 - 6.5e-08 32.9 1.4 0.51 10.9 0.0 7.0 8 1 1 9 9 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CBY22688.1 - 2.8e-07 31.1 0.1 0.6 10.7 0.0 4.9 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CBY22688.1 - 3e-06 27.4 3.3 1.5 8.8 0.0 5.9 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBY22688.1 - 5e-06 26.3 11.5 1.5 9.3 0.0 8.6 12 0 0 12 12 8 1 HEAT repeat CLASP_N PF12348.8 CBY22688.1 - 4.9e-05 23.0 0.9 2.5 7.6 0.0 4.1 3 1 1 4 4 4 2 CLASP N terminal UME PF08064.13 CBY22688.1 - 0.0053 16.6 0.0 6.9 6.6 0.0 5.2 5 1 2 7 7 7 1 UME (NUC010) domain NUC173 PF08161.12 CBY22688.1 - 0.0058 16.3 0.3 3.4 7.3 0.0 4.4 3 3 2 5 5 5 1 NUC173 domain TAF6_C PF07571.13 CBY22688.1 - 0.0072 16.6 0.0 0.13 12.6 0.0 2.9 2 1 0 2 2 1 1 TAF6 C-terminal HEAT repeat domain IFRD PF05004.13 CBY22688.1 - 0.016 14.3 0.1 4.6 6.2 0.0 3.4 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) Dopey_N PF04118.14 CBY22688.1 - 0.046 12.8 1.3 4.3 6.4 0.0 3.9 3 1 0 4 4 4 0 Dopey, N-terminal DUF1428 PF07237.11 CBY22688.1 - 0.1 12.9 0.2 0.56 10.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) DRIM PF07539.12 CBY22688.1 - 0.13 10.5 1.7 23 3.1 0.0 3.5 2 1 1 4 4 4 0 Down-regulated in metastasis BCL_N PF04714.13 CBY22689.1 - 2.4e-22 78.7 6.0 3.8e-22 78.1 6.0 1.4 1 0 0 1 1 1 1 BCL7, N-terminal conserver region PH PF00169.29 CBY22689.1 - 0.023 15.2 0.1 0.029 14.9 0.1 1.2 1 0 0 1 1 1 0 PH domain STE3 PF02076.15 CBY22690.1 - 0.02 14.1 1.0 0.034 13.4 0.9 1.5 1 1 0 1 1 1 0 Pheromone A receptor Cytochrom_B561 PF03188.16 CBY22690.1 - 0.089 12.9 0.1 0.089 12.9 0.1 2.4 2 1 0 3 3 3 0 Eukaryotic cytochrome b561 YL1_C PF08265.11 CBY22690.1 - 2.4 8.0 4.7 19 5.1 0.0 3.2 2 1 1 3 3 3 0 YL1 nuclear protein C-terminal domain Acyltransferase PF01553.21 CBY22691.1 - 7.8e-12 45.0 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF4239 PF14023.6 CBY22691.1 - 0.07 12.8 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Ribosomal_L16 PF00252.18 CBY22692.1 - 7.9e-42 142.4 0.1 9.4e-42 142.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e WD40 PF00400.32 CBY22693.1 - 6.7e-06 26.7 2.9 0.54 11.2 0.2 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat Gallidermin PF02052.15 CBY22694.1 - 0.25 11.7 1.8 1.7 9.1 0.4 2.4 2 0 0 2 2 2 0 Gallidermin Tho2 PF11262.8 CBY22695.1 - 8e-101 337.2 2.8 1.5e-100 336.3 2.8 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 CBY22695.1 - 1.8e-78 264.8 4.1 4e-53 181.0 0.7 4.3 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 CBY22695.1 - 8.4e-34 115.5 0.0 2.2e-33 114.1 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit T4SS-DNA_transf PF02534.14 CBY22695.1 - 0.026 13.3 1.3 0.048 12.5 1.3 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer GCR1_C PF12550.8 CBY22695.1 - 0.067 13.5 1.0 0.84 10.0 0.2 3.1 3 0 0 3 3 3 0 Transcriptional activator of glycolytic enzymes YjfB_motility PF14070.6 CBY22695.1 - 0.17 12.1 0.1 0.53 10.5 0.2 1.8 2 0 0 2 2 2 0 Putative motility protein UPF0154 PF03672.13 CBY22695.1 - 0.29 11.2 2.4 2.7 8.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF4404 PF14357.6 CBY22695.1 - 7.1 7.4 7.6 12 6.6 2.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) NDK PF00334.19 CBY22696.1 - 5.1e-44 149.6 0.0 6.9e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 CBY22696.1 - 3.4e-13 49.1 0.0 5.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Med12-LCEWAV PF12145.8 CBY22698.1 - 2.2e-54 185.1 0.5 1.8e-52 178.8 0.5 3.2 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 CBY22698.1 - 5.3e-07 29.8 0.0 2e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 THDPS_N_2 PF14805.6 CBY22699.1 - 0.093 13.0 0.7 4 7.7 0.0 3.5 4 0 0 4 4 4 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal PTase_Orf2 PF11468.8 CBY22700.1 - 0.077 12.4 1.1 0.12 11.8 1.1 1.2 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 Brix PF04427.18 CBY22701.1 - 3.6e-41 141.4 2.2 3.6e-41 141.4 2.2 1.5 2 0 0 2 2 2 1 Brix domain PPP4R2 PF09184.11 CBY22701.1 - 0.026 14.1 7.8 0.042 13.5 7.8 1.3 1 0 0 1 1 1 0 PPP4R2 DUF5308 PF17233.2 CBY22701.1 - 0.075 13.3 1.1 0.15 12.3 1.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5308) PPL5 PF18168.1 CBY22701.1 - 0.5 9.6 5.3 0.83 8.9 5.3 1.3 1 0 0 1 1 1 0 Prim-pol family 5 MDM10 PF12519.8 CBY22701.1 - 0.67 8.8 4.3 1 8.1 4.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PIEZO PF15917.5 CBY22701.1 - 4.7 6.6 12.5 10 5.5 12.5 1.5 1 0 0 1 1 1 0 Piezo Sulfatase PF00884.23 CBY22702.1 - 1.9e-45 155.6 0.9 3.1e-45 154.9 0.9 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY22702.1 - 0.0015 18.2 1.6 0.0066 16.1 1.6 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Citrate_bind PF16114.5 CBY22703.1 - 1e-91 305.3 0.0 2e-91 304.3 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Ligase_CoA PF00549.19 CBY22703.1 - 7.7e-14 51.8 0.1 3.8e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_2 PF08442.10 CBY22703.1 - 0.00021 20.9 0.0 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.21 CBY22703.1 - 0.00044 19.4 0.8 0.011 14.9 0.3 2.4 2 1 1 3 3 3 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 CBY22703.1 - 0.062 14.0 0.1 0.17 12.6 0.1 1.8 1 0 0 1 1 1 0 CoA binding domain SET PF00856.28 CBY22704.1 - 2.8e-14 53.8 0.1 2.8e-14 53.8 0.1 2.8 3 0 0 3 3 3 1 SET domain zf-MYND PF01753.18 CBY22704.1 - 2.3e-10 40.4 14.2 2.3e-10 40.4 14.2 1.8 2 0 0 2 2 1 1 MYND finger TPR_12 PF13424.6 CBY22704.1 - 2e-09 37.6 7.2 0.0022 18.2 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY22704.1 - 0.00032 20.6 2.6 0.091 12.9 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBY22704.1 - 0.005 16.7 7.7 0.25 11.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY22704.1 - 0.012 15.6 0.5 5 7.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 CBY22704.1 - 0.017 15.5 6.3 0.043 14.1 6.3 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TPR_14 PF13428.6 CBY22704.1 - 0.022 15.5 5.3 0.28 12.1 0.0 3.3 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY22704.1 - 0.026 14.4 2.5 0.21 11.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NuDC PF16273.5 CBY22704.1 - 0.62 10.6 20.1 7.7 7.1 20.1 2.6 1 1 0 1 1 1 0 Nuclear distribution C domain 4HB_MCP_1 PF12729.7 CBY22704.1 - 6.2 6.3 10.4 6.8 6.2 1.2 3.4 3 1 0 3 3 3 0 Four helix bundle sensory module for signal transduction Citrate_synt PF00285.21 CBY22705.1 - 6.6e-14 51.8 0.0 5.3e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain SLBB PF10531.9 CBY22705.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 SLBB domain LrgB PF04172.16 CBY22706.1 - 0.45 10.0 6.4 6.8 6.2 1.7 2.6 2 0 0 2 2 2 0 LrgB-like family Ion_trans PF00520.31 CBY22707.1 - 4.7e-237 782.5 90.3 2.7e-70 236.4 10.1 4.1 4 0 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.13 CBY22707.1 - 2.1e-14 54.3 4.1 2.1e-14 54.3 4.1 2.0 2 0 0 2 2 2 1 Sodium ion transport-associated PKD_channel PF08016.12 CBY22707.1 - 1.7e-11 43.5 79.9 2.2e-05 23.3 1.8 9.9 6 4 4 10 10 10 7 Polycystin cation channel GPHH PF16905.5 CBY22707.1 - 8e-06 25.5 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Na_trans_cytopl PF11933.8 CBY22707.1 - 0.0021 17.9 0.2 0.0021 17.9 0.2 2.1 3 0 0 3 3 3 1 Cytoplasmic domain of voltage-gated Na+ ion channel UPF0239 PF06783.11 CBY22707.1 - 0.088 13.0 0.6 0.62 10.3 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Zip PF02535.22 CBY22707.1 - 0.76 8.9 0.0 0.76 8.9 0.0 3.8 4 0 0 4 4 4 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CBY22708.1 - 3.4e-34 119.0 10.6 9.7e-34 117.5 10.6 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY22708.1 - 8.5e-26 90.7 0.9 1.8e-25 89.7 0.9 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1616 PF07760.11 CBY22708.1 - 0.085 12.2 2.8 0.14 11.6 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF1286 PF06939.11 CBY22708.1 - 0.39 11.0 6.3 0.69 10.2 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1286) MIG-14_Wnt-bd PF06664.12 CBY22709.1 - 0.051 12.8 3.7 0.066 12.4 3.7 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion PI3_PI4_kinase PF00454.27 CBY22711.1 - 2.2e-36 126.0 1.7 4.4e-24 85.7 0.3 3.7 3 1 1 4 4 4 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CBY22711.1 - 2e-26 92.5 0.0 9.2e-26 90.4 0.0 2.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2779 PF11074.8 CBY22711.1 - 0.011 16.1 0.2 5.6 7.4 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) DUF4135 PF13575.6 CBY22711.1 - 0.015 14.7 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TBK1_ULD PF18396.1 CBY22712.1 - 0.036 14.0 0.3 0.18 11.7 0.1 2.3 3 0 0 3 3 3 0 TANK binding kinase 1 ubiquitin-like domain CBFD_NFYB_HMF PF00808.23 CBY22713.1 - 6.6e-16 58.4 0.3 6.6e-16 58.4 0.3 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY22713.1 - 1.7e-06 28.4 0.1 1.7e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 HGTP_anticodon2 PF12745.7 CBY22713.1 - 0.0036 16.9 2.9 0.0042 16.6 2.9 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs CENP-T_C PF15511.6 CBY22713.1 - 0.0061 16.7 0.1 0.01 15.9 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Peptidase_S49_N PF08496.10 CBY22713.1 - 0.12 12.4 4.5 0.15 12.1 4.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1840 PF08895.11 CBY22713.1 - 9.7 6.6 10.3 17 5.8 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) UQ_con PF00179.26 CBY22714.1 - 4.1e-46 156.1 0.0 4.7e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY22714.1 - 0.0002 21.6 0.0 0.00024 21.4 0.0 1.3 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CBY22714.1 - 0.0033 17.1 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B V-SNARE_C PF12352.8 CBY22715.1 - 2.5e-07 30.9 1.5 2.5e-07 30.9 1.5 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus TMF_TATA_bd PF12325.8 CBY22715.1 - 0.0025 18.0 1.7 0.0025 18.0 1.7 2.2 2 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding BORCS7 PF16088.5 CBY22715.1 - 0.015 15.6 0.2 0.015 15.6 0.2 2.4 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF745 PF05335.13 CBY22715.1 - 0.096 12.4 4.3 0.17 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) MAD PF05557.13 CBY22715.1 - 0.16 10.3 11.0 0.016 13.6 1.3 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein FPP PF05911.11 CBY22715.1 - 0.16 10.1 10.3 0.18 10.0 0.9 2.0 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil UPF0449 PF15136.6 CBY22715.1 - 0.71 10.4 7.1 0.18 12.3 0.8 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF5089 PF17002.5 CBY22715.1 - 1.1 9.1 12.9 15 5.4 12.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) APG6_N PF17675.1 CBY22715.1 - 5.7 7.5 10.6 0.4 11.2 2.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Laminin_II PF06009.12 CBY22715.1 - 8.4 6.4 10.2 4.5 7.3 4.2 2.1 2 0 0 2 2 2 0 Laminin Domain II OPA3 PF07047.12 CBY22716.1 - 4.1e-07 29.8 0.0 1.2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) CENP-F_leu_zip PF10473.9 CBY22716.1 - 0.00021 21.3 5.4 0.00032 20.7 5.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 CBY22716.1 - 0.00098 19.2 3.5 0.00098 19.2 3.5 1.7 2 0 0 2 2 2 1 bZIP transcription factor FlaC_arch PF05377.11 CBY22716.1 - 0.0092 16.3 1.6 0.0092 16.3 1.6 2.0 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) DUF4763 PF15960.5 CBY22716.1 - 0.02 14.2 1.2 0.03 13.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) JAKMIP_CC3 PF16034.5 CBY22716.1 - 0.03 14.3 1.4 0.048 13.6 1.4 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain JIP_LZII PF16471.5 CBY22716.1 - 0.15 12.2 4.4 0.36 11.0 4.2 1.7 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II TSC22 PF01166.18 CBY22716.1 - 0.18 12.2 1.6 2.3 8.6 0.2 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF1664 PF07889.12 CBY22716.1 - 0.18 11.8 1.4 0.35 10.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 CBY22716.1 - 0.25 11.4 0.8 0.4 10.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DivIC PF04977.15 CBY22716.1 - 0.28 11.0 2.1 0.72 9.7 0.7 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 CBY22716.1 - 0.44 10.7 3.9 1.9 8.6 0.2 2.5 1 1 1 2 2 2 0 Basic region leucine zipper AAA PF00004.29 CBY22717.1 - 9.6e-43 145.8 0.0 2.5e-42 144.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY22717.1 - 7.8e-10 38.4 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBY22717.1 - 2.7e-07 30.9 0.0 8.1e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CBY22717.1 - 3.4e-07 30.1 0.0 7.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CBY22717.1 - 1.6e-06 28.2 0.0 8.3e-06 25.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY22717.1 - 6e-06 26.7 0.5 9e-05 22.9 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 CBY22717.1 - 8.7e-05 22.3 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBY22717.1 - 0.00025 21.3 2.9 0.009 16.3 0.4 3.1 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.6 CBY22717.1 - 0.0012 19.4 2.3 0.022 15.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CBY22717.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBY22717.1 - 0.0016 17.7 0.0 0.0036 16.5 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CBY22717.1 - 0.0027 17.5 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBY22717.1 - 0.0067 15.8 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBY22717.1 - 0.0085 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CBY22717.1 - 0.0094 15.4 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein ATPase PF06745.13 CBY22717.1 - 0.0099 15.3 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_11 PF13086.6 CBY22717.1 - 0.015 15.1 3.4 0.47 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CBY22717.1 - 0.022 14.5 0.0 0.13 11.9 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 CBY22717.1 - 0.023 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBY22717.1 - 0.024 14.4 0.0 0.075 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY22717.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CBY22717.1 - 0.043 13.8 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CBY22717.1 - 0.053 12.6 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 CBY22717.1 - 0.066 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBY22717.1 - 0.07 12.7 0.2 0.2 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 CBY22717.1 - 0.072 13.4 0.0 0.54 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBY22717.1 - 0.073 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 CBY22717.1 - 0.075 13.4 0.6 0.38 11.2 0.0 2.5 3 0 0 3 3 2 0 AAA domain Spc24 PF08286.11 CBY22717.1 - 0.57 10.5 3.9 0.93 9.8 1.9 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HSP90 PF00183.18 CBY22718.1 - 5.9e-211 701.8 23.7 8e-211 701.4 23.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBY22718.1 - 2.5e-13 50.5 0.1 4.5e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBY22718.1 - 6.8e-11 42.2 0.3 1.7e-10 40.8 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prion_bPrPp PF11587.8 CBY22719.1 - 0.22 11.4 0.5 0.37 10.6 0.5 1.3 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal Galactosyl_T PF01762.21 CBY22720.1 - 9.7e-21 74.5 0.0 1.8e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase HTS PF04204.16 CBY22720.1 - 0.098 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Homoserine O-succinyltransferase MauE PF07291.11 CBY22722.1 - 0.052 13.3 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Methylamine utilisation protein MauE Lectin_C PF00059.21 CBY22723.1 - 5.7e-30 104.2 13.9 3.4e-10 40.6 0.3 3.5 3 0 0 3 3 3 3 Lectin C-type domain Xlink PF00193.17 CBY22723.1 - 0.00075 19.8 3.3 4.4 7.8 0.3 4.5 5 0 0 5 5 5 2 Extracellular link domain Chordopox_A33R PF05966.12 CBY22723.1 - 0.21 10.8 8.7 0.83 8.9 0.0 3.3 4 0 0 4 4 4 0 Chordopoxvirus A33R protein cEGF PF12662.7 CBY22724.1 - 1.3e-06 28.2 3.1 1.3e-06 28.2 3.1 2.3 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY22724.1 - 2.3e-05 24.5 9.0 2.3e-05 24.5 9.0 3.3 2 1 0 3 3 3 2 Calcium-binding EGF domain FOLN PF09289.10 CBY22724.1 - 0.019 15.1 2.8 0.019 15.1 2.8 2.3 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain EGF PF00008.27 CBY22724.1 - 0.064 13.6 15.9 0.43 10.9 0.2 3.7 3 0 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.6 CBY22724.1 - 0.15 12.4 7.5 0.55 10.6 0.1 2.8 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CBY22724.1 - 0.17 12.1 12.8 0.33 11.2 3.9 2.9 2 1 0 2 2 2 0 EGF domain hEGF PF12661.7 CBY22724.1 - 6.5 7.6 15.2 6.4 7.6 0.1 3.8 4 0 0 4 4 4 0 Human growth factor-like EGF zf-RING_2 PF13639.6 CBY22725.1 - 2.4e-07 30.9 5.4 2.4e-07 30.9 5.4 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY22725.1 - 7.5e-07 29.1 5.0 2.7e-06 27.3 1.9 3.0 2 2 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY22725.1 - 1.4e-06 28.1 9.2 5.5e-06 26.2 5.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY22725.1 - 2.8e-06 27.0 4.8 2.8e-06 27.0 4.8 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CBY22725.1 - 3.4e-06 26.9 6.3 3.4e-06 26.9 6.3 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY22725.1 - 7.8e-05 22.5 9.4 0.00014 21.7 5.9 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.11 CBY22725.1 - 0.00077 19.7 4.7 0.0012 19.1 4.7 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) COG5 PF10392.9 CBY22725.1 - 0.0088 16.2 1.9 0.015 15.4 1.9 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 zf-C3HC4_2 PF13923.6 CBY22725.1 - 0.015 15.1 10.8 0.015 15.1 10.8 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY22725.1 - 0.027 14.6 10.8 0.038 14.2 5.2 3.6 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING MPS2 PF17060.5 CBY22725.1 - 0.06 12.6 7.9 0.078 12.2 7.9 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Exonuc_VII_L PF02601.15 CBY22725.1 - 0.075 12.6 2.5 0.1 12.2 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-Q PF13094.6 CBY22725.1 - 0.12 12.5 6.7 0.2 11.9 6.7 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit LMBR1 PF04791.16 CBY22725.1 - 1.2 8.0 4.4 1.4 7.7 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zinc_ribbon_5 PF13719.6 CBY22725.1 - 1.5 8.6 7.1 2 8.3 0.1 3.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF3847 PF12958.7 CBY22725.1 - 1.9 8.6 10.0 0.25 11.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) V_ATPase_I PF01496.19 CBY22725.1 - 3.2 5.6 6.1 4 5.2 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CBY22725.1 - 9.7 5.3 7.0 13 4.9 7.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein VWA_3 PF13768.6 CBY22726.1 - 0.0043 17.0 0.3 0.26 11.2 0.3 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF155 PF02582.14 CBY22726.1 - 0.015 15.4 4.5 0.016 15.3 2.7 1.9 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 MIEAP PF16026.5 CBY22726.1 - 0.45 10.7 8.0 1.5 9.0 5.8 2.3 2 0 0 2 2 2 0 Mitochondria-eating protein Mucin PF01456.17 CBY22726.1 - 1.7 8.6 64.5 0.014 15.4 26.6 2.5 1 1 1 2 2 2 0 Mucin-like glycoprotein VWA PF00092.28 CBY22727.1 - 1.2e-07 32.1 1.2 2.5e-06 27.9 1.2 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY22727.1 - 0.00023 21.8 0.2 0.00074 20.1 0.2 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY22727.1 - 0.002 18.1 0.3 0.13 12.2 0.3 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain ALS2CR11 PF15729.5 CBY22730.1 - 2.5e-19 69.8 0.5 4.9e-19 68.8 0.5 1.4 1 1 0 1 1 1 1 Amyotrophic lateral sclerosis 2 candidate 11 DUF4989 PF16379.5 CBY22730.1 - 0.059 12.7 0.1 0.4 9.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4989) Serpin PF00079.20 CBY22731.1 - 3.8e-10 39.6 0.0 5.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Ribosomal_S6 PF01250.17 CBY22731.1 - 0.044 14.0 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6 DdrB PF12747.7 CBY22731.1 - 0.047 13.5 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 DdrB-like protein Serpin PF00079.20 CBY22732.1 - 1.5e-08 34.4 0.4 7.6e-08 32.1 0.4 1.9 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Rsc14 PF08586.10 CBY22732.1 - 0.28 12.0 1.8 0.34 11.8 0.4 1.8 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit AP3D1 PF06375.11 CBY22732.1 - 0.95 9.7 8.0 0.22 11.8 4.4 1.8 2 1 1 3 3 3 0 AP-3 complex subunit delta-1 Ephrin_rec_like PF07699.13 CBY22733.1 - 0.00013 21.7 20.4 0.00049 19.8 12.3 85.8 63 22 28 94 94 94 44 Putative ephrin-receptor like SBDS_C PF09377.10 CBY22733.1 - 8.1 6.5 8.3 8.4 6.4 0.0 4.1 4 0 0 4 4 4 0 SBDS protein C-terminal domain SH3BGR PF04908.15 CBY22734.1 - 2.2e-20 72.6 0.0 2.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 CBY22734.1 - 0.041 14.1 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin ABC_tran_Xtn PF12848.7 CBY22734.1 - 0.15 12.1 0.1 5.9 7.0 0.1 2.3 2 0 0 2 2 2 0 ABC transporter Glyco_transf_49 PF13896.6 CBY22735.1 - 6.5e-75 252.5 0.0 7.4e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Pkinase PF00069.25 CBY22736.1 - 3.4e-08 33.2 0.3 2.9e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22736.1 - 0.0019 17.5 0.0 0.0072 15.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Mrr_cat_2 PF13156.6 CBY22736.1 - 0.51 10.2 2.7 2 8.3 0.4 2.7 2 0 0 2 2 2 0 Restriction endonuclease BCAS3 PF12490.8 CBY22737.1 - 2.2e-17 63.4 0.4 5.9e-17 62.0 0.4 1.7 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 CBY22737.1 - 4.2 8.4 4.7 16 6.5 1.4 3.1 1 1 1 2 2 2 0 WD domain, G-beta repeat Metallophos PF00149.28 CBY22738.1 - 3.8e-33 115.7 0.0 6.7e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ITI_HC_C PF06668.12 CBY22739.1 - 0.0074 16.0 0.1 0.015 14.9 0.1 1.5 1 1 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Ras PF00071.22 CBY22741.1 - 5.3e-50 169.2 0.2 6.1e-50 169.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY22741.1 - 1e-32 112.9 0.0 1.8e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY22741.1 - 1.1e-13 51.0 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY22741.1 - 1.8e-08 34.0 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY22741.1 - 4.8e-08 33.1 0.0 9.9e-08 32.1 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBY22741.1 - 2.8e-05 23.6 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY22741.1 - 0.00053 19.6 0.1 0.029 13.9 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CBY22741.1 - 0.00083 18.8 0.0 0.0043 16.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial TniB protein G-alpha PF00503.20 CBY22741.1 - 0.0046 16.2 0.2 0.06 12.5 0.1 2.1 1 1 0 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 CBY22741.1 - 0.0089 15.8 0.1 0.015 15.1 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CBY22741.1 - 0.02 14.6 0.0 0.19 11.5 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 CBY22741.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBY22741.1 - 0.11 12.3 0.3 0.28 11.0 0.3 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SAM_3 PF18016.1 CBY22742.1 - 1.7e-24 85.4 0.0 3.4e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PTB PF08416.13 CBY22742.1 - 6.9e-12 45.7 0.1 1.3e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_9 PF14604.6 CBY22742.1 - 2.2e-08 33.8 0.0 4.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY22742.1 - 5.1e-08 32.4 0.0 9.3e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY22742.1 - 1.7e-07 30.8 0.0 3.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_PNT PF02198.16 CBY22742.1 - 0.0055 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PDZ PF00595.24 CBY22743.1 - 2e-19 69.7 0.6 3.1e-19 69.1 0.6 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY22743.1 - 3.5e-06 27.3 0.1 5e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY22743.1 - 3.6e-06 26.7 0.0 5.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Cytochrom_B561 PF03188.16 CBY22745.1 - 7.2e-11 42.4 6.8 7.2e-11 42.4 6.8 1.8 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 CBY22745.1 - 0.025 14.7 2.9 0.031 14.4 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF3793 PF12672.7 CBY22745.1 - 0.032 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DUF3021 PF11457.8 CBY22745.1 - 3.9 7.8 10.4 4.4 7.6 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) DUF4131 PF13567.6 CBY22745.1 - 6.6 6.4 8.5 5.6 6.6 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Aconitase PF00330.20 CBY22746.1 - 8.7e-177 588.7 0.0 1.2e-176 588.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CBY22746.1 - 2.5e-40 137.8 0.0 1.1e-39 135.7 0.0 2.1 2 0 0 2 2 2 1 Aconitase C-terminal domain adh_short_C2 PF13561.6 CBY22747.1 - 9.6e-46 156.2 0.2 1.3e-45 155.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY22747.1 - 3e-34 118.2 0.6 3.9e-34 117.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY22747.1 - 1.2e-09 38.3 0.3 1.9e-09 37.7 0.3 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CBY22747.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY22747.1 - 0.036 13.5 0.1 0.067 12.6 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CBY22747.1 - 0.036 13.9 0.5 0.059 13.2 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CBY22747.1 - 0.048 13.8 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CDV3 PF15359.6 CBY22748.1 - 0.12 12.8 13.0 0.09 13.3 11.0 1.9 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 HLH PF00010.26 CBY22749.1 - 2.1e-16 59.6 1.6 6.9e-16 57.9 1.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NosL PF05573.12 CBY22749.1 - 0.047 14.1 0.2 1 9.7 0.1 2.9 4 0 0 4 4 4 0 NosL PDZ_assoc PF10600.9 CBY22749.1 - 9.6 7.1 8.0 29 5.6 0.9 2.9 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors Ank_2 PF12796.7 CBY22750.1 - 1.8e-27 95.8 4.1 6.4e-17 61.9 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY22750.1 - 1.2e-17 63.7 0.1 7.9e-09 35.6 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY22750.1 - 1.7e-14 53.5 4.0 7.8e-06 26.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CBY22750.1 - 2.5e-14 53.4 0.5 9.2e-10 38.9 0.2 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY22750.1 - 3.7e-12 45.3 0.3 0.0018 18.6 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat APG6_N PF17675.1 CBY22750.1 - 0.011 16.3 10.9 0.025 15.1 10.9 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Rootletin PF15035.6 CBY22750.1 - 0.011 15.8 10.1 0.042 13.9 10.1 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 CBY22750.1 - 0.042 14.0 7.5 0.069 13.3 7.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CBY22750.1 - 3.2 8.4 9.5 1.7e+02 2.9 9.5 2.6 1 1 0 1 1 1 0 Initiation control protein YabA fn3 PF00041.21 CBY22751.1 - 0.053 13.9 0.0 0.087 13.2 0.0 1.5 1 1 0 1 1 1 0 Fibronectin type III domain Tetraspanin PF00335.20 CBY22752.1 - 0.00011 22.0 9.2 0.00011 22.0 9.2 1.9 2 0 0 2 2 2 1 Tetraspanin family HMG_box PF00505.19 CBY22753.1 - 8.1e-26 90.2 3.4 1.4e-25 89.5 3.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY22753.1 - 8.3e-11 42.3 2.3 1.4e-10 41.6 2.3 1.4 1 0 0 1 1 1 1 HMG-box domain IL3 PF02059.15 CBY22754.1 - 0.097 12.7 1.5 0.11 12.6 0.4 1.6 2 0 0 2 2 2 0 Interleukin-3 THEG PF14912.6 CBY22755.1 - 1.3e-10 41.6 6.0 9.7e-05 22.7 0.1 3.2 1 1 2 3 3 3 3 Testicular haploid expressed repeat Pkinase PF00069.25 CBY22756.1 - 5e-44 150.6 0.0 2.7e-28 99.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22756.1 - 1.5e-25 90.0 0.0 2.4e-17 63.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY22756.1 - 0.00011 21.1 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY22756.1 - 0.014 15.3 0.1 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CBY22756.1 - 0.025 13.9 0.0 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBY22756.1 - 0.041 13.5 0.1 6 6.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PKcGMP_CC PF16808.5 CBY22756.1 - 1.2 9.1 5.9 2.4 8.1 1.6 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BBP1_C PF15272.6 CBY22757.1 - 0.0028 17.5 1.3 0.003 17.4 1.3 1.0 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Cdh1_DBD_1 PF18196.1 CBY22757.1 - 0.018 15.3 0.8 0.023 15.0 0.8 1.2 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 YgbB PF02542.16 CBY22757.1 - 0.021 15.1 0.5 0.026 14.8 0.5 1.1 1 0 0 1 1 1 0 YgbB family DUF919 PF06034.11 CBY22757.1 - 0.022 14.6 0.6 0.041 13.7 0.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF530 PF04409.12 CBY22757.1 - 0.025 12.9 0.4 0.031 12.7 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF530) DUF3818 PF12825.7 CBY22757.1 - 0.052 12.6 0.8 0.054 12.5 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) HAP1_N PF04849.13 CBY22759.1 - 1.8e-42 145.7 27.1 2.6e-42 145.1 27.1 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ERM PF00769.19 CBY22759.1 - 0.0009 19.1 12.9 0.0009 19.1 12.9 3.6 3 1 0 4 4 4 1 Ezrin/radixin/moesin family Lipoprotein_7 PF01540.16 CBY22759.1 - 0.0075 15.6 5.0 0.0075 15.6 5.0 2.1 2 0 0 2 2 2 1 Adhesin lipoprotein DUF2935 PF11155.8 CBY22759.1 - 0.011 16.1 0.1 0.28 11.5 0.1 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) RasGAP_C PF03836.15 CBY22759.1 - 0.016 15.3 0.2 0.016 15.3 0.2 3.6 3 1 0 3 3 2 0 RasGAP C-terminus Snapin_Pallidin PF14712.6 CBY22759.1 - 0.025 15.0 3.8 0.025 15.0 3.8 3.8 2 1 2 4 4 4 0 Snapin/Pallidin DivIVA PF05103.13 CBY22759.1 - 0.029 14.5 0.2 0.029 14.5 0.2 3.7 3 1 1 4 4 3 0 DivIVA protein Myosin_tail_1 PF01576.19 CBY22759.1 - 0.044 11.6 28.5 0.064 11.1 18.3 2.2 2 0 0 2 2 2 0 Myosin tail GIT_CC PF16559.5 CBY22759.1 - 0.05 13.5 12.0 0.66 9.9 1.6 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 CBY22759.1 - 0.057 13.7 16.4 0.093 13.1 2.4 3.8 4 0 0 4 4 4 0 TSC-22/dip/bun family TTRAP PF14203.6 CBY22759.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.5 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein DUF5624 PF18538.1 CBY22759.1 - 0.18 11.9 0.5 0.57 10.3 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Milton PF12448.8 CBY22759.1 - 0.19 11.8 8.8 0.032 14.3 2.8 2.6 2 1 0 2 2 2 0 Kinesin associated protein Fib_alpha PF08702.10 CBY22759.1 - 0.34 11.1 20.2 0.19 11.9 4.1 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 CBY22759.1 - 0.43 9.9 18.5 2.4 7.4 16.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) FAD-SLDH PF12318.8 CBY22759.1 - 1.1 9.2 6.5 0.67 10.0 0.4 2.7 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Sec20 PF03908.13 CBY22759.1 - 1.2 9.1 13.8 0.7 9.9 2.0 3.6 4 1 0 4 4 3 0 Sec20 DUF1664 PF07889.12 CBY22759.1 - 1.4 8.9 17.7 4.9 7.2 0.2 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) TMCO5 PF14992.6 CBY22759.1 - 4.7 6.7 24.2 2.2 7.8 14.0 2.3 2 0 0 2 2 2 0 TMCO5 family Leu_zip PF15294.6 CBY22759.1 - 4.8 6.6 22.7 1.4 8.3 11.4 2.6 1 1 1 2 2 2 0 Leucine zipper KxDL PF10241.9 CBY22759.1 - 5.1 7.4 15.2 0.41 10.9 0.7 4.0 2 1 2 4 4 4 0 Uncharacterized conserved protein Herpes_BLRF2 PF05812.12 CBY22759.1 - 5.9 7.1 13.1 0.21 11.8 4.1 3.0 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DUF948 PF06103.11 CBY22759.1 - 9.8 6.5 11.6 4.8 7.5 0.5 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DSPc PF00782.20 CBY22760.1 - 4.8e-27 94.4 0.0 5.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBY22760.1 - 0.0029 17.2 0.0 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CBY22760.1 - 0.01 16.0 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 CBY22760.1 - 0.017 15.4 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain BATS PF06968.13 CBY22761.1 - 0.009 16.1 0.0 0.058 13.5 0.0 2.2 1 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Methyltr_RsmB-F PF01189.17 CBY22761.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Not3 PF04065.15 CBY22762.1 - 1.4e-71 240.6 26.5 1.4e-71 240.6 26.5 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CBY22762.1 - 1.8e-41 141.3 11.3 1.8e-41 141.3 11.3 2.5 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2433 PF10360.9 CBY22762.1 - 1.1 9.3 4.8 0.68 10.0 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) DUF2203 PF09969.9 CBY22762.1 - 4.6 8.0 9.1 1 10.1 2.5 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HR1 PF02185.16 CBY22762.1 - 7.7 6.7 11.0 1.3 9.2 2.8 2.7 2 0 0 2 2 2 0 Hr1 repeat TUDOR PF00567.24 CBY22763.1 - 1.4e-07 31.5 0.1 4.7e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Tudor domain GCP_C_terminal PF04130.13 CBY22764.1 - 8.3e-23 81.3 4.2 9.2e-23 81.2 4.2 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Pecanex_C PF05041.15 CBY22764.1 - 0.033 13.8 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 Pecanex protein (C-terminus) CH PF00307.31 CBY22766.1 - 4.6e-21 75.1 0.1 3.4e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Sec1 PF00995.23 CBY22767.1 - 3.4e-71 241.2 0.1 4.1e-71 240.9 0.1 1.0 1 0 0 1 1 1 1 Sec1 family DiSB-ORF2_chro PF16506.5 CBY22767.1 - 0.029 14.4 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Putative virion glycoprotein of insect viruses Sec1 PF00995.23 CBY22768.1 - 2.8e-09 36.8 0.0 3.3e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PDZ_2 PF13180.6 CBY22770.1 - 2.1e-06 28.0 0.0 5.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY22770.1 - 6.8e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY22770.1 - 1.6e-05 25.2 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PITH PF06201.13 CBY22771.1 - 3.1e-39 134.6 1.0 4.6e-39 134.1 1.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 CBY22771.1 - 1.4e-23 82.8 0.2 3.5e-23 81.5 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBY22771.1 - 0.0017 18.8 0.4 0.05 14.1 0.4 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CBY22771.1 - 0.0047 16.7 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBY22771.1 - 0.012 15.9 0.0 0.15 12.4 0.0 2.6 2 1 1 3 3 3 0 Thioredoxin-like DUF1779 PF08680.10 CBY22771.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 TATA-box binding HyaE PF07449.11 CBY22771.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Dimer_Tnp_hAT PF05699.14 CBY22772.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Lung_7-TM_R PF06814.13 CBY22773.1 - 7.8e-61 205.9 14.7 1e-60 205.5 14.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor CcmB PF03379.13 CBY22773.1 - 0.024 14.1 3.1 0.16 11.5 0.7 2.2 2 0 0 2 2 2 0 CcmB protein DUF2681 PF10883.8 CBY22773.1 - 0.24 11.9 2.4 15 6.1 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF2231 PF09990.9 CBY22773.1 - 5.7 7.4 9.8 3.9 8.0 0.8 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) Ribosomal_L4 PF00573.22 CBY22774.1 - 8.2e-39 133.3 1.0 1.3e-38 132.7 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CBY22774.1 - 7.5e-26 90.0 4.8 7.5e-26 90.0 4.8 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Metallophos PF00149.28 CBY22775.1 - 2.6e-11 44.4 0.3 4.4e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Phospholip_A2_1 PF00068.19 CBY22776.1 - 2.9e-11 43.8 0.2 4.1e-11 43.3 0.2 1.2 1 0 0 1 1 1 1 Phospholipase A2 FA_hydroxylase PF04116.13 CBY22777.1 - 7.4e-24 84.6 12.6 7.4e-24 84.6 12.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ldl_recept_a PF00057.18 CBY22778.1 - 5.9e-53 176.8 138.1 4.5e-09 36.4 15.2 9.2 8 1 1 9 9 9 8 Low-density lipoprotein receptor domain class A Trypsin PF00089.26 CBY22778.1 - 7.3e-49 166.5 0.0 1.2e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Fz PF01392.22 CBY22778.1 - 1.8e-18 67.1 2.9 1.8e-18 67.1 2.9 5.7 4 3 1 5 5 5 1 Fz domain Glutaminase PF04960.15 CBY22779.1 - 2.7e-93 312.3 0.4 3.8e-93 311.8 0.4 1.2 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.7 CBY22779.1 - 1.2e-12 48.2 0.0 2.6e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY22779.1 - 2.1e-08 34.6 0.2 1.4e-07 31.9 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) EF-hand_14 PF17959.1 CBY22779.1 - 3.3e-08 33.8 0.1 1.2e-07 32.0 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain Ank_3 PF13606.6 CBY22779.1 - 2e-06 27.7 0.1 0.45 11.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CBY22779.1 - 0.0028 18.0 0.0 5.8 7.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY22779.1 - 0.0063 16.8 0.2 0.51 10.7 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-C4 PF00105.18 CBY22780.1 - 1.5e-29 102.2 14.1 2.8e-29 101.4 14.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ChaC PF04752.12 CBY22780.1 - 0.1 12.7 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 ChaC-like protein SRCR PF00530.18 CBY22782.1 - 6.5e-15 55.4 6.7 6.5e-15 55.4 6.7 2.2 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Lectin_C PF00059.21 CBY22782.1 - 5.2e-08 33.6 1.4 1.4e-07 32.2 0.1 2.4 2 0 0 2 2 2 1 Lectin C-type domain TSP_1 PF00090.19 CBY22782.1 - 0.016 15.5 8.8 0.016 15.5 8.8 2.6 2 0 0 2 2 2 0 Thrombospondin type 1 domain SRCR PF00530.18 CBY22783.1 - 9.9e-32 109.4 14.9 1.1e-17 64.4 0.1 4.4 3 1 1 4 4 4 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 CBY22783.1 - 7.5e-10 39.2 6.2 4.1e-05 24.1 0.0 3.8 3 1 1 4 4 4 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 CBY22783.1 - 0.00056 20.4 0.4 0.34 11.5 0.0 3.6 4 0 0 4 4 4 2 Hepsin, SRCR domain Hydrolase_6 PF13344.6 CBY22784.1 - 1.4e-18 66.9 0.0 4.4e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY22784.1 - 4.8e-05 23.3 0.0 0.0021 18.1 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CBY22784.1 - 0.13 12.5 0.0 6.9 6.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase EF1_GNE PF00736.19 CBY22785.1 - 1.4e-33 114.9 1.0 1.4e-33 114.9 1.0 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CBY22785.1 - 3e-14 53.2 5.3 3e-14 53.2 5.3 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Cnn_1N PF07989.11 CBY22785.1 - 0.0039 17.3 0.5 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Cwf_Cwc_15 PF04889.12 CBY22785.1 - 0.037 13.8 5.9 0.044 13.5 5.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Wtap PF17098.5 CBY22785.1 - 0.043 13.8 0.2 0.07 13.1 0.2 1.5 1 0 0 1 1 1 0 WTAP/Mum2p family NOP5NT PF08156.13 CBY22785.1 - 0.071 13.5 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 NOP5NT (NUC127) domain Ax_dynein_light PF10211.9 CBY22785.1 - 0.12 12.4 1.7 0.36 10.8 1.4 1.9 1 1 0 1 1 1 0 Axonemal dynein light chain CASP_C PF08172.12 CBY22785.1 - 0.19 11.0 1.5 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 CASP C terminal Matrilin_ccoil PF10393.9 CBY22785.1 - 0.38 10.7 1.9 0.39 10.6 0.3 2.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin SlyX PF04102.12 CBY22785.1 - 3 8.5 4.7 3.9 8.2 0.1 2.8 3 0 0 3 3 3 0 SlyX Phytoreo_Pns PF05451.11 CBY22786.1 - 0.082 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 Sulfotransfer_3 PF13469.6 CBY22787.1 - 1.2e-08 35.6 0.1 0.0022 18.4 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY22787.1 - 8.9e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain RRM_1 PF00076.22 CBY22788.1 - 1.4e-46 156.2 0.5 3.9e-16 58.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY22788.1 - 6.2e-05 22.6 0.0 0.28 10.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3338 PF11819.8 CBY22788.1 - 0.0079 16.2 0.3 0.016 15.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) RRM_7 PF16367.5 CBY22788.1 - 0.0089 16.1 0.0 0.064 13.4 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 CBY22788.1 - 0.019 14.8 0.0 0.18 11.6 0.0 2.3 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 CBY22788.1 - 0.038 14.0 0.0 8.5 6.5 0.0 2.7 2 1 0 2 2 2 0 RNA binding domain Nup35_RRM_2 PF14605.6 CBY22788.1 - 0.063 13.3 0.1 2.6 8.1 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif HD PF01966.22 CBY22789.1 - 0.0066 16.7 2.6 0.0076 16.5 0.6 2.1 1 1 1 2 2 2 2 HD domain DcpS_C PF11969.8 CBY22790.1 - 2.1e-19 70.1 0.4 2.6e-19 69.8 0.4 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CBY22790.1 - 5.6e-11 43.0 5.9 1.7e-10 41.5 5.9 1.7 1 1 0 1 1 1 1 HIT domain GalP_UDP_tr_C PF02744.17 CBY22790.1 - 0.0093 15.7 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain CwfJ_C_1 PF04677.15 CBY22790.1 - 0.055 13.3 0.1 0.066 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 CDH PF02611.15 CBY22790.1 - 0.13 11.9 0.2 2.8 7.5 0.0 2.0 2 0 0 2 2 2 0 CDP-diacylglycerol pyrophosphatase Smg8_Smg9 PF10220.9 CBY22792.1 - 8e-140 467.8 3.9 1e-90 305.4 0.9 3.0 1 1 2 3 3 3 3 Smg8_Smg9 Dynein_IC2 PF11540.8 CBY22793.1 - 1.2e-11 44.3 3.8 2.8e-11 43.1 3.8 1.7 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 CBY22793.1 - 6.4e-10 39.5 12.5 0.3 12.0 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY22793.1 - 0.00074 19.8 0.1 0.024 14.9 0.0 3.4 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WW_like PF17890.1 CBY22793.1 - 0.014 15.4 0.1 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 Peptidoglycan hydrolase LytB WW-like domain Atg14 PF10186.9 CBY22793.1 - 0.18 10.9 1.9 0.32 10.0 1.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3446 PF11928.8 CBY22794.1 - 1.9 8.8 14.7 4.4 7.7 14.7 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain Cnd2 PF05786.14 CBY22795.1 - 1.3e-28 100.2 30.8 1.2e-27 96.9 30.8 2.3 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CBY22795.1 - 6.7e-06 26.3 1.0 6.7e-06 26.3 1.0 3.1 2 1 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Actin PF00022.19 CBY22796.1 - 1.3e-66 224.9 0.0 2.5e-65 220.7 0.0 1.9 1 1 0 1 1 1 1 Actin zf-C3HC4_3 PF13920.6 CBY22797.1 - 0.49 10.3 20.4 4.2 7.3 0.7 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF4042 PF13251.6 CBY22799.1 - 5.7e-18 65.3 4.0 1.6e-17 63.8 1.4 2.8 2 1 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT PF02985.22 CBY22799.1 - 0.0023 18.0 2.6 1.6 9.2 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat Lactamase_B PF00753.27 CBY22800.1 - 2.4e-23 83.2 0.0 3.6e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 CBY22800.1 - 2.5e-07 30.6 0.1 5.2e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 CBY22800.1 - 1.6e-05 24.5 0.1 2.5e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 CBY22800.1 - 0.0016 18.0 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBY22800.1 - 0.032 14.1 0.2 0.11 12.4 0.1 1.7 2 1 0 2 2 2 0 Beta-lactamase superfamily domain S10_plectin PF03501.15 CBY22801.1 - 5.4e-39 132.2 0.1 9e-39 131.4 0.1 1.4 1 0 0 1 1 1 1 Plectin/S10 domain Tex_N PF09371.10 CBY22801.1 - 0.011 15.4 1.1 0.022 14.4 0.4 1.9 1 1 1 2 2 2 0 Tex-like protein N-terminal domain PP_kinase_C_1 PF17941.1 CBY22801.1 - 0.036 13.6 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 NPV_P10 PF05531.12 CBY22801.1 - 0.11 13.0 0.6 0.3 11.6 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ribosomal_S26e PF01283.19 CBY22802.1 - 6.1e-50 168.2 9.2 7e-50 168.0 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e LSM PF01423.22 CBY22803.1 - 2.8e-14 52.6 0.1 4.9e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 LSM domain BRD4_CDT PF17105.5 CBY22803.1 - 0.16 11.6 3.5 0.27 10.9 3.5 1.3 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 LSM PF01423.22 CBY22804.1 - 4.7e-17 61.4 0.5 5.6e-17 61.2 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY22804.1 - 7.2e-06 26.1 0.2 9.8e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain PTCB-BRCT PF12738.7 CBY22805.1 - 6.4e-32 109.3 4.6 6.3e-12 45.3 0.0 4.5 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 CBY22805.1 - 7.8e-28 96.7 3.4 8.6e-07 29.2 0.0 7.0 6 1 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBY22805.1 - 8.6e-18 64.5 0.6 0.0029 18.0 0.0 6.2 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CBY22805.1 - 6.1e-17 61.3 0.1 2.1e-11 43.5 0.0 4.2 5 0 0 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 CBY22805.1 - 2.1e-05 24.7 1.4 2.9 8.2 0.1 4.1 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain AKAP28 PF14469.6 CBY22806.1 - 0.036 13.8 0.6 0.068 12.9 0.1 1.7 2 0 0 2 2 2 0 28 kDa A-kinase anchor NUMOD3 PF07460.11 CBY22806.1 - 0.096 12.9 0.1 0.46 10.7 0.2 2.0 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) DUF4483 PF14825.6 CBY22807.1 - 6.1e-48 162.6 0.2 1e-47 161.9 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4483) Pkinase PF00069.25 CBY22808.1 - 1.1e-11 44.6 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22808.1 - 1.8e-05 24.2 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Phosducin PF02114.16 CBY22809.1 - 1.6e-13 50.2 0.1 7.4e-09 34.9 0.0 2.1 1 1 0 2 2 2 2 Phosducin CbiZ PF01955.18 CBY22809.1 - 0.07 13.2 0.1 0.35 10.9 0.0 2.0 3 0 0 3 3 3 0 Adenosylcobinamide amidohydrolase TPR_19 PF14559.6 CBY22810.1 - 1.1e-18 67.4 11.3 0.00048 20.6 0.2 7.0 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBY22810.1 - 8.1e-11 41.2 24.9 0.00012 21.9 0.2 8.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY22810.1 - 1.5e-10 41.2 3.1 0.31 11.4 0.2 7.3 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY22810.1 - 6.4e-08 32.1 21.0 0.015 15.1 0.3 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY22810.1 - 1.2e-05 25.5 19.9 0.035 14.3 2.7 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CBY22810.1 - 3.3e-05 24.3 6.0 1.3 10.0 0.0 6.7 7 2 2 9 9 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY22810.1 - 3.6e-05 24.3 0.0 0.42 11.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY22810.1 - 0.00015 21.4 12.1 0.00057 19.5 0.8 4.5 5 0 0 5 5 5 2 TPR repeat TPR_8 PF13181.6 CBY22810.1 - 0.00018 21.5 20.5 0.18 12.1 0.0 6.5 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBY22810.1 - 0.0018 18.2 14.5 1.7 8.9 0.1 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat MIT PF04212.18 CBY22810.1 - 0.0035 17.4 8.1 0.041 14.0 0.4 4.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 CBY22810.1 - 0.022 14.9 0.2 14 5.9 0.0 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBY22810.1 - 0.11 12.9 8.0 7.7 6.9 0.0 4.6 5 1 1 6 6 5 0 Tetratricopeptide repeat HU-CCDC81_bac_2 PF18175.1 CBY22810.1 - 0.25 11.2 4.4 0.25 11.2 0.2 3.1 4 0 0 4 4 2 0 CCDC81-like prokaryotic HU domain 2 EMP24_GP25L PF01105.24 CBY22810.1 - 0.55 10.1 3.6 0.7 9.8 0.1 2.5 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD TPR_21 PF09976.9 CBY22810.1 - 1.4 8.6 12.8 3.6 7.2 0.1 4.4 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 CBY22810.1 - 2.1 9.2 15.1 9.2 7.2 0.0 6.5 7 1 0 7 7 5 0 Tetratricopeptide repeat RPT PF13446.6 CBY22810.1 - 2.4 8.2 4.9 3 7.8 0.2 3.5 4 0 0 4 4 3 0 A repeated domain in UCH-protein 4HB_MCP_1 PF12729.7 CBY22810.1 - 3.3 7.2 11.8 2.8 7.5 2.5 3.6 4 0 0 4 4 4 0 Four helix bundle sensory module for signal transduction SRP_TPR_like PF17004.5 CBY22810.1 - 5.3 7.1 22.7 0.097 12.7 2.6 5.0 2 2 2 4 4 4 0 Putative TPR-like repeat TPR_15 PF13429.6 CBY22810.1 - 9.5 5.3 11.2 1.7 7.8 4.1 2.9 2 2 0 2 2 2 0 Tetratricopeptide repeat Cyclin_N PF00134.23 CBY22811.1 - 2.5e-42 143.6 0.8 4.7e-42 142.7 0.8 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY22811.1 - 2.8e-24 85.5 0.2 7e-24 84.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Rpn9_C PF18261.1 CBY22811.1 - 0.11 12.1 0.1 3.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Rpn9 C-terminal helix Striatin PF08232.12 CBY22812.1 - 0.59 10.7 5.8 1.1 9.8 5.8 1.4 1 0 0 1 1 1 0 Striatin family SHIPPO-rpt PF07004.12 CBY22814.1 - 4.7e-15 55.7 23.5 2.8e-05 24.8 1.9 5.0 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat Ras PF00071.22 CBY22815.1 - 5.9e-11 42.2 0.1 5.2e-08 32.7 0.1 2.1 1 1 0 1 1 1 1 Ras family ATP-gua_Ptrans PF00217.19 CBY22816.1 - 7.7e-59 198.7 0.0 1e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY22816.1 - 1.9e-25 89.0 0.0 3.1e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Rad21_Rec8_N PF04825.13 CBY22818.1 - 1.3e-13 51.0 0.1 2.9e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CBY22818.1 - 7e-07 28.4 0.0 1.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein CNDH2_N PF06278.11 CBY22818.1 - 0.0011 19.1 0.1 0.0032 17.6 0.1 1.7 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF3213 PF11491.8 CBY22818.1 - 0.026 14.7 0.4 0.28 11.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) Isochorismatase PF00857.20 CBY22819.1 - 6.2e-31 107.9 0.0 7.3e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF3439 PF11921.8 CBY22820.1 - 0.14 12.1 0.8 0.25 11.3 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NUDIX PF00293.28 CBY22823.1 - 0.00017 21.7 0.0 0.00031 20.8 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain MCR_beta_N PF02783.15 CBY22823.1 - 0.021 14.5 0.2 0.031 13.9 0.2 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Heme_oxygenase PF01126.20 CBY22824.1 - 9.4e-12 45.1 0.1 2.1e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 Heme oxygenase Lipase_GDSL PF00657.22 CBY22825.1 - 4.8e-09 36.5 0.0 1.1e-07 32.1 0.0 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Cu-binding_MopE PF11617.8 CBY22825.1 - 0.00013 22.1 1.1 0.00063 19.8 1.0 2.2 2 0 0 2 2 2 1 Putative metal-binding motif RBD-FIP PF09457.10 CBY22826.1 - 4.5e-07 29.7 0.1 1.2e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 FIP domain SHE3 PF17078.5 CBY22826.1 - 0.018 14.8 3.9 0.04 13.6 3.9 1.5 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF3450 PF11932.8 CBY22826.1 - 0.023 14.0 0.2 0.038 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Baculo_gp64 PF03273.13 CBY22826.1 - 0.043 12.6 0.2 0.062 12.1 0.2 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family FAM76 PF16046.5 CBY22826.1 - 0.34 10.2 12.9 0.65 9.3 12.8 1.6 1 1 0 1 1 1 0 FAM76 protein KELK PF15796.5 CBY22826.1 - 0.54 10.8 5.6 1.2 9.6 5.6 1.6 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase BRCA-2_OB1 PF09103.10 CBY22827.1 - 1.2e-19 70.4 2.4 6.4e-18 64.9 0.2 3.9 3 1 0 3 3 3 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_OB3 PF09104.10 CBY22827.1 - 1.7e-08 34.2 0.1 4.2e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA-2_helical PF09169.10 CBY22827.1 - 0.00029 20.5 2.3 0.00062 19.5 0.0 2.5 2 1 0 2 2 2 1 BRCA2, helical tRNA_anti-codon PF01336.25 CBY22827.1 - 0.013 15.4 0.0 6.2 6.9 0.0 2.7 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF3006 PF11213.8 CBY22827.1 - 0.047 13.9 0.1 0.46 10.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) K1 PF02960.14 CBY22828.1 - 0.21 11.7 0.0 0.54 10.4 0.0 1.6 1 0 0 1 1 1 0 K1 glycoprotein Glyco_transf_64 PF09258.10 CBY22829.1 - 2.3e-88 295.7 0.0 4.7e-88 294.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 CBY22829.1 - 4.4e-12 45.8 0.0 2.2e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 Exostosin family Glycos_transf_2 PF00535.26 CBY22829.1 - 0.00049 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Fib_alpha PF08702.10 CBY22829.1 - 0.06 13.5 2.9 5.1 7.3 4.9 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 CBY22829.1 - 0.063 13.6 4.3 0.12 12.6 4.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Glyco_tranf_2_3 PF13641.6 CBY22829.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 End3 PF12761.7 CBY22829.1 - 3.2 7.9 7.4 4.9 7.3 7.4 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 FPP PF05911.11 CBY22829.1 - 6 4.9 8.3 8.4 4.4 8.3 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF16 PF01519.16 CBY22829.1 - 7.7 7.1 7.4 17 6.0 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Methyltransf_PK PF05891.12 CBY22830.1 - 9.2e-63 211.7 0.0 1.1e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CBY22830.1 - 7.6e-06 26.5 0.0 1.2e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY22830.1 - 1.5e-05 24.9 0.0 3.1e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY22830.1 - 4.4e-05 24.1 0.1 0.00012 22.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY22830.1 - 0.051 14.3 0.0 0.078 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CBY22830.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 CBY22830.1 - 0.098 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Mei5 PF10376.9 CBY22830.1 - 0.13 12.1 0.2 0.6 9.9 0.0 1.8 2 0 0 2 2 2 0 Double-strand recombination repair protein zf-CCHH PF10283.9 CBY22831.1 - 1.1e-19 70.0 11.7 2.3e-11 43.5 2.7 2.4 2 0 0 2 2 2 2 PBZ domain PBP1_TM PF14812.6 CBY22831.1 - 3.2 8.2 8.2 0.8 10.1 3.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chromo PF00385.24 CBY22832.1 - 1.3e-19 69.8 1.7 5.2e-16 58.3 0.9 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CBY22832.1 - 6.9e-14 51.7 0.1 2.2e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Mtf2_C PF14061.6 CBY22832.1 - 3.2e-06 27.2 0.1 0.00025 21.2 0.1 2.4 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 PWWP PF00855.17 CBY22833.1 - 9.8e-23 80.4 21.8 9.3e-14 51.6 0.2 4.8 4 1 0 4 4 4 2 PWWP domain SET PF00856.28 CBY22833.1 - 6.4e-20 72.2 0.1 6.4e-20 72.2 0.1 3.6 3 2 0 3 3 3 1 SET domain AWS PF17907.1 CBY22833.1 - 1.4e-07 31.4 10.7 6.5e-07 29.3 10.7 2.2 1 0 0 1 1 1 1 AWS domain PHD PF00628.29 CBY22833.1 - 1.3e-05 24.9 6.3 1.3e-05 24.9 6.3 6.0 4 1 1 5 5 5 2 PHD-finger zf-C2H2_9 PF16293.5 CBY22833.1 - 1.4 8.8 6.3 4.8 7.1 1.8 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) Thioredoxin PF00085.20 CBY22834.1 - 2.7e-25 88.4 0.0 3.2e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBY22834.1 - 1.3e-06 28.4 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBY22834.1 - 9.7e-06 26.0 0.1 0.00022 21.7 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CBY22834.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBY22834.1 - 0.0091 16.3 0.1 0.028 14.7 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 CBY22835.1 - 5.1e-10 39.3 0.2 6.7e-10 38.9 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBY22835.1 - 0.00065 20.0 0.3 0.044 14.1 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 CBY22835.1 - 0.042 13.9 0.1 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin domain Ribosomal_L24e PF01246.20 CBY22836.1 - 1.7e-32 111.5 7.6 1.7e-32 111.5 7.6 2.1 3 1 0 3 3 3 1 Ribosomal protein L24e MCM PF00493.23 CBY22837.1 - 2.5e-100 334.2 0.0 3.9e-100 333.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY22837.1 - 2.7e-34 117.7 0.3 4.6e-34 117.0 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBY22837.1 - 1.1e-23 83.5 3.5 1.4e-23 83.1 0.8 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CBY22837.1 - 1.1e-10 42.0 0.3 4.4e-10 40.1 0.3 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY22837.1 - 2.5e-09 36.8 0.0 1.2e-06 28.1 0.0 2.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 CBY22837.1 - 2.7e-08 34.3 36.5 2.7e-08 34.3 36.5 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 CBY22837.1 - 1.4e-06 28.3 0.0 5.1e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY22837.1 - 1.3e-05 25.1 0.0 0.0014 18.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY22837.1 - 0.00059 19.6 0.0 0.011 15.4 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 CBY22837.1 - 0.018 15.5 0.0 0.061 13.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.10 CBY22837.1 - 0.3 11.2 1.4 0.79 9.9 1.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain RNA_pol_Rpb2_6 PF00562.28 CBY22838.1 - 6.1e-117 391.0 0.1 9.4e-117 390.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBY22838.1 - 1.4e-63 214.1 0.0 2e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CBY22838.1 - 6e-48 163.0 0.0 1.2e-47 162.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CBY22838.1 - 4.8e-34 116.6 1.3 9e-34 115.7 0.3 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CBY22838.1 - 6.4e-24 83.9 0.0 1.6e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 CBY22838.1 - 1.1e-23 83.2 1.3 2.3e-23 82.2 1.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CBY22838.1 - 9.3e-18 64.5 2.8 2.5e-17 63.1 2.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_POL_M_15KD PF02150.16 CBY22838.1 - 0.85 9.5 5.4 2.1 8.3 1.6 2.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Ribosomal_L19e PF01280.20 CBY22839.1 - 2.7e-63 212.3 9.7 2.7e-63 212.3 9.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e DUF2202 PF09968.9 CBY22839.1 - 0.026 14.4 0.9 0.026 14.4 0.9 1.5 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) DUF4602 PF15375.6 CBY22839.1 - 2.6 8.4 17.2 0.33 11.3 13.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) ubiquitin PF00240.23 CBY22840.1 - 3e-34 116.6 1.2 4.2e-34 116.1 0.4 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 CBY22840.1 - 2.7e-22 78.6 1.0 6.1e-22 77.5 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CBY22840.1 - 2.4e-16 59.3 0.5 4.1e-16 58.6 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBY22840.1 - 2.4e-06 27.9 0.8 9.8e-05 22.7 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBY22840.1 - 0.00057 20.0 0.9 0.0013 18.8 0.9 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBY22840.1 - 0.0038 17.8 0.9 0.0055 17.2 0.9 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 CBY22840.1 - 0.0062 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBY22840.1 - 0.0076 16.6 0.1 0.0076 16.6 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 CBY22840.1 - 0.13 12.3 4.2 5.8 7.0 0.2 2.6 3 0 0 3 3 3 0 Ubiquitin-like domain Plexin_cytopl PF08337.12 CBY22840.1 - 0.37 9.4 3.1 4.1 5.9 0.6 2.2 2 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Neur_chan_memb PF02932.16 CBY22842.1 - 1.9e-62 211.5 13.3 2.8e-49 168.3 12.4 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY22842.1 - 3.3e-60 203.2 0.1 3.3e-60 203.2 0.1 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.9 CBY22842.1 - 0.013 14.9 6.5 0.024 14.0 3.0 2.1 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Bromodomain PF00439.25 CBY22842.1 - 0.17 11.9 0.8 7.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Bromodomain PMP22_Claudin PF00822.20 CBY22843.1 - 2.2e-10 40.7 3.3 2.2e-10 40.7 3.3 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY22843.1 - 7.8e-10 39.2 5.6 1.2e-09 38.6 5.6 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CBY22843.1 - 0.075 12.8 12.7 1.4 8.7 11.7 2.8 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2157 PF09925.9 CBY22843.1 - 0.64 9.8 9.2 0.054 13.3 1.6 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Phage_holin_5_2 PF16079.5 CBY22843.1 - 0.89 9.9 0.0 0.89 9.9 0.0 3.0 3 1 1 4 4 4 0 Phage holin family Hol44, in holin superfamily V Amastin PF07344.11 CBY22843.1 - 0.92 9.3 9.6 1.4 8.8 9.3 1.7 1 1 0 1 1 1 0 Amastin surface glycoprotein Halogen_Hydrol PF10112.9 CBY22843.1 - 4.8 7.1 4.4 39 4.2 0.0 3.0 1 1 2 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF1218 PF06749.12 CBY22843.1 - 5.2 7.7 14.6 0.37 11.3 6.0 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1218) NB PF04159.13 CBY22844.1 - 0.0053 16.8 4.6 0.061 13.4 0.8 2.6 2 0 0 2 2 2 2 NB glycoprotein MRP-S28 PF10213.9 CBY22845.1 - 0.026 14.9 0.6 0.051 14.0 0.6 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein UPF0242 PF06785.11 CBY22845.1 - 0.8 9.8 10.0 1.2 9.2 6.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 CBY22845.1 - 5.2 6.1 10.3 15 4.5 10.8 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2_jaz PF12171.8 CBY22846.1 - 3.9e-07 30.2 0.1 9.2e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY22846.1 - 1.4e-06 28.5 0.4 2.8e-06 27.5 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.12 CBY22846.1 - 0.003 17.8 0.7 0.0069 16.6 0.7 1.6 1 1 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-U1 PF06220.12 CBY22846.1 - 0.0035 17.1 2.8 0.031 14.0 1.4 2.3 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_2 PF12756.7 CBY22846.1 - 0.036 14.4 0.9 0.06 13.7 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CLZ PF16526.5 CBY22847.1 - 0.028 14.8 0.3 1.3 9.4 0.1 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_25 PF13481.6 CBY22848.1 - 2.8e-18 66.2 0.0 4.3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CBY22848.1 - 8.1e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 CBY22848.1 - 2.8e-12 46.5 0.1 7e-12 45.2 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 CBY22848.1 - 3.1e-05 24.3 0.0 7.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY22848.1 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CBY22848.1 - 0.014 15.1 0.1 0.084 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain Propep_M14 PF02244.16 CBY22848.1 - 0.11 12.9 1.9 12 6.4 0.0 3.3 3 0 0 3 3 3 0 Carboxypeptidase activation peptide AAA_29 PF13555.6 CBY22848.1 - 0.17 11.7 0.1 0.51 10.1 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY22848.1 - 0.22 12.0 2.5 0.64 10.5 2.5 1.9 1 1 0 1 1 1 0 AAA domain Sel1 PF08238.12 CBY22849.1 - 8.7e-09 35.8 1.1 0.04 14.6 0.0 4.5 4 1 0 4 4 4 3 Sel1 repeat TPR_1 PF00515.28 CBY22849.1 - 0.16 11.9 1.0 5.3 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat fn2 PF00040.19 CBY22850.1 - 0.0034 17.6 0.1 0.0071 16.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type II domain Sel1 PF08238.12 CBY22850.1 - 0.012 16.3 8.0 0.32 11.8 0.1 3.1 3 1 0 3 3 3 0 Sel1 repeat DUF1964 PF09244.10 CBY22850.1 - 0.12 12.8 0.0 29 5.2 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1964) MFS_1 PF07690.16 CBY22853.1 - 3.4e-05 23.0 1.5 4.5e-05 22.5 1.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RhoGEF PF00621.20 CBY22854.1 - 4.1e-22 79.3 10.3 4.7e-22 79.1 7.2 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 CBY22854.1 - 0.0031 18.0 0.2 0.0071 16.8 0.2 1.6 1 0 0 1 1 1 1 PH domain APG6_N PF17675.1 CBY22854.1 - 9 6.8 10.8 2.3 8.7 0.2 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region RhoGAP PF00620.27 CBY22855.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 RhoGAP domain RRM_1 PF00076.22 CBY22856.1 - 1.5e-28 98.4 0.0 1.9e-13 50.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TDP43_N PF18694.1 CBY22856.1 - 1e-21 76.5 0.0 2.2e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_7 PF16367.5 CBY22856.1 - 1.4e-05 25.1 0.0 0.023 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CBY22856.1 - 8.8e-05 22.4 0.2 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY22856.1 - 0.0043 17.1 0.1 0.67 10.0 0.1 2.5 1 1 1 2 2 2 2 RNA binding motif RL PF17797.1 CBY22856.1 - 0.009 15.9 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 1 RL domain ATP-synt_ab PF00006.25 CBY22857.1 - 2.1e-68 230.2 0.0 3.8e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CBY22857.1 - 3.2e-46 156.7 0.9 5.5e-46 156.0 0.9 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CBY22857.1 - 8.8e-19 67.8 1.6 2.3e-18 66.4 1.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CBY22857.1 - 0.034 14.3 0.3 0.077 13.1 0.3 1.6 1 0 0 1 1 1 0 HAS barrel domain MarR_2 PF12802.7 CBY22857.1 - 0.11 12.4 0.8 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 MarR family DUF3591 PF12157.8 CBY22858.1 - 1.2e-133 446.1 0.0 3.5e-133 444.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 CBY22858.1 - 2.6e-39 133.2 3.5 5.5e-19 68.0 0.3 2.9 2 0 0 2 2 2 2 Bromodomain Tmemb_cc2 PF10267.9 CBY22858.1 - 1.2e-14 54.2 32.7 2.6e-09 36.7 8.3 6.3 5 2 1 6 6 6 2 Predicted transmembrane and coiled-coil 2 protein TBP-binding PF09247.11 CBY22858.1 - 1.3e-12 47.7 2.5 1.3e-12 47.7 2.5 2.6 3 0 0 3 3 3 1 TATA box-binding protein binding PCMT PF01135.19 CBY22859.1 - 1.2e-54 185.3 0.0 1.4e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CBY22859.1 - 5.9e-06 26.9 0.0 1.2e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY22859.1 - 5.3e-05 23.1 0.0 8.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY22859.1 - 0.0012 18.7 0.3 0.0028 17.5 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY22859.1 - 0.0017 19.0 0.0 0.004 17.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBY22859.1 - 0.0028 17.7 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBY22859.1 - 0.0044 16.3 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 CBY22859.1 - 0.063 12.9 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 CBY22859.1 - 0.066 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 CBY22859.1 - 0.19 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DAO PF01266.24 CBY22860.1 - 1.7e-17 64.0 0.0 3e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Neur_chan_memb PF02932.16 CBY22861.1 - 0.0045 17.1 0.8 0.0094 16.0 0.8 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Sema PF01403.19 CBY22861.1 - 0.0084 15.0 0.1 0.023 13.5 0.1 1.8 1 0 0 1 1 1 1 Sema domain HEAT_2 PF13646.6 CBY22862.1 - 0.00012 22.4 0.2 0.015 15.7 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 CBY22862.1 - 0.00088 19.3 0.7 0.0044 17.1 0.4 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBY22862.1 - 0.014 15.6 0.1 23 5.6 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat DUF1539 PF07560.11 CBY22862.1 - 0.032 14.3 0.0 0.29 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) MOR2-PAG1_C PF14225.6 CBY22862.1 - 0.072 12.9 1.3 0.14 12.0 0.2 2.1 2 1 0 2 2 2 0 Cell morphogenesis C-terminal DCB PF16213.5 CBY22862.1 - 3 7.5 6.0 0.52 10.0 0.5 2.5 2 1 1 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 PAP2 PF01569.21 CBY22864.1 - 5.2e-26 91.0 3.2 1.1e-25 89.9 0.8 2.4 2 1 0 2 2 2 1 PAP2 superfamily DUF2569 PF10754.9 CBY22864.1 - 0.013 16.0 0.9 0.013 16.0 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF4153 PF13687.6 CBY22864.1 - 0.017 14.7 1.1 0.042 13.5 1.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4153) Glycophorin_A PF01102.18 CBY22864.1 - 0.017 15.3 1.0 0.42 10.9 0.0 2.9 2 1 0 3 3 3 0 Glycophorin A Colicin_V PF02674.16 CBY22864.1 - 0.03 14.3 5.8 6.2 6.8 1.9 3.4 2 2 0 2 2 2 0 Colicin V production protein PAP2_3 PF14378.6 CBY22864.1 - 0.041 13.6 1.1 6.5 6.4 0.5 2.5 2 0 0 2 2 2 0 PAP2 superfamily DUF212 PF02681.14 CBY22864.1 - 0.06 13.5 0.0 5.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Divergent PAP2 family DUF2061 PF09834.9 CBY22864.1 - 0.14 12.7 1.5 2.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) HLH PF00010.26 CBY22866.1 - 1.8e-08 34.2 0.4 7.7e-08 32.2 0.2 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Peptidase_C2 PF00648.21 CBY22867.1 - 2.7e-39 135.0 0.0 4.6e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CBY22867.1 - 2e-13 50.8 0.2 0.002 18.4 0.0 3.5 2 1 1 3 3 3 3 Calpain large subunit, domain III NKAIN PF05640.14 CBY22867.1 - 0.35 10.1 1.2 0.81 8.9 0.2 1.9 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein Sulfotransfer_3 PF13469.6 CBY22868.1 - 0.0006 20.3 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY22868.1 - 0.0062 16.0 0.5 0.02 14.4 0.5 1.9 1 1 0 1 1 1 1 Sulfotransferase domain QIL1 PF15884.5 CBY22868.1 - 0.12 13.0 0.5 0.63 10.7 0.0 2.3 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 SF1-HH PF16275.5 CBY22869.1 - 4e-36 123.8 3.6 9.8e-36 122.5 3.6 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CBY22869.1 - 2.5e-06 27.2 0.1 7.6e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 CBY22869.1 - 0.0023 17.9 1.0 0.0046 17.0 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle GCN5L1 PF06320.13 CBY22869.1 - 0.14 12.3 0.6 0.42 10.8 0.1 1.9 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) zf-CCHC_3 PF13917.6 CBY22869.1 - 0.15 12.0 0.2 0.58 10.2 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L14 PF00238.19 CBY22870.1 - 6.7e-11 42.3 0.0 7.7e-10 38.9 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e Nop PF01798.18 CBY22871.1 - 8.9e-66 221.6 0.0 1.4e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CBY22871.1 - 6.7e-42 143.2 2.2 1.3e-41 142.3 2.2 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Mrx7 PF10906.8 CBY22871.1 - 0.12 12.6 0.0 0.54 10.5 0.0 2.1 3 0 0 3 3 3 0 MIOREX complex component 7 Cpn60_TCP1 PF00118.24 CBY22872.1 - 8.5e-160 532.6 5.3 1e-159 532.3 5.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PRP3 PF08572.10 CBY22873.1 - 4.8e-57 193.3 23.7 4.8e-57 193.3 23.7 3.2 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CBY22873.1 - 1.2e-34 119.5 3.6 1.2e-34 119.5 3.6 4.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) PWI PF01480.17 CBY22873.1 - 0.00038 20.7 0.0 0.002 18.4 0.0 2.3 1 0 0 1 1 1 1 PWI domain DER1 PF04511.15 CBY22874.1 - 2.7e-59 200.3 8.8 3.1e-59 200.1 8.8 1.0 1 0 0 1 1 1 1 Der1-like family FKBP_C PF00254.28 CBY22875.1 - 1.1e-34 118.6 0.0 1.4e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RSB_motif PF16294.5 CBY22876.1 - 1e-14 54.6 4.6 1e-14 54.6 4.6 6.3 4 2 2 6 6 6 2 RNSP1-SAP18 binding (RSB) motif Oxidored_q6 PF01058.22 CBY22878.1 - 6.8e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Adenylsucc_synt PF00709.21 CBY22879.1 - 5.1e-169 562.6 0.0 5.8e-169 562.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase EF-hand_1 PF00036.32 CBY22880.1 - 3.2e-25 85.7 9.6 2.1e-07 30.0 1.5 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY22880.1 - 2.2e-24 85.7 6.0 2.5e-16 59.8 0.4 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CBY22880.1 - 4.1e-22 76.2 6.2 2.3e-06 27.1 0.1 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 CBY22880.1 - 2.9e-18 64.5 10.5 1.4e-05 24.4 0.1 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CBY22880.1 - 1.4e-15 56.9 8.3 1.1e-06 28.4 0.2 3.7 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CBY22880.1 - 2.5e-06 27.4 6.0 0.032 14.2 0.1 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY22880.1 - 2.7e-05 24.4 0.5 0.042 14.2 0.2 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CBY22880.1 - 0.00027 21.1 1.2 0.88 9.8 0.0 2.8 2 1 1 3 3 3 3 Dockerin type I domain EF-hand_9 PF14658.6 CBY22880.1 - 0.003 17.8 0.4 6.1 7.2 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain GLTP PF08718.11 CBY22881.1 - 3.5e-39 134.4 0.0 4.9e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Fcf1 PF04900.12 CBY22882.1 - 1.9e-24 85.9 0.0 4e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Fcf1 DUF4342 PF14242.6 CBY22882.1 - 0.054 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Complex1_30kDa PF00329.19 CBY22884.1 - 2.1e-40 138.1 0.0 3.7e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2443 PF10398.9 CBY22885.1 - 0.0023 17.9 0.1 0.0064 16.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2443) Glycos_transf_2 PF00535.26 CBY22887.1 - 8.6e-27 94.0 0.0 1.8e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY22887.1 - 3.5e-12 46.7 2.0 7.7e-12 45.6 2.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 CBY22887.1 - 2.2e-06 27.7 0.0 4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CBY22887.1 - 2.4e-05 23.9 0.1 7.7e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY22887.1 - 0.00055 19.5 0.0 0.0081 15.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Ac76 PF05814.11 CBY22887.1 - 0.057 13.4 1.5 0.18 11.8 1.5 1.9 1 0 0 1 1 1 0 Orf76 (Ac76) AT_hook PF02178.19 CBY22887.1 - 3 8.0 11.4 6.8 6.9 5.7 2.8 2 0 0 2 2 2 0 AT hook motif DUF3593 PF12159.8 CBY22888.1 - 0.013 15.5 0.3 0.029 14.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) DUF4190 PF13828.6 CBY22888.1 - 0.04 13.7 5.4 0.097 12.4 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4190) DHHC PF01529.20 CBY22888.1 - 0.34 11.0 2.4 0.74 9.9 2.4 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase ASC PF00858.24 CBY22890.1 - 8.4e-13 48.1 0.9 8.4e-13 48.1 0.9 1.4 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel Transposase_22 PF02994.14 CBY22891.1 - 0.034 14.3 0.1 0.074 13.2 0.0 1.6 1 1 1 2 2 2 0 L1 transposable element RBD-like domain Ribosomal_L30_N PF08079.12 CBY22895.1 - 0.0017 18.5 1.0 0.83 10.0 0.8 2.7 2 0 0 2 2 2 2 Ribosomal L30 N-terminal domain Sporozoite_P67 PF05642.11 CBY22895.1 - 0.0037 15.4 0.1 0.004 15.3 0.1 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4718 PF15842.5 CBY22895.1 - 0.25 11.2 2.4 0.41 10.4 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) AJAP1_PANP_C PF15298.6 CBY22895.1 - 0.36 11.0 15.5 0.6 10.3 15.5 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus MGC-24 PF05283.11 CBY22895.1 - 0.75 10.2 17.8 0.068 13.6 11.5 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 CBY22895.1 - 2.9 7.9 32.9 0.11 12.5 23.1 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.12 CBY22895.1 - 4.3 5.2 10.1 5.3 4.9 10.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gal-3-0_sulfotr PF06990.11 CBY22897.1 - 5.4e-31 107.9 0.4 6.8e-30 104.3 0.4 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY22897.1 - 1.7e-06 28.1 0.4 4.8e-06 26.7 0.2 1.8 1 1 0 1 1 1 1 Sulfotransferase family EF-hand_1 PF00036.32 CBY22898.1 - 2e-11 42.6 1.5 6.7e-06 25.3 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY22898.1 - 2.2e-11 42.7 1.9 3.1e-05 23.5 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY22898.1 - 7.9e-08 32.6 0.5 0.0023 18.4 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY22898.1 - 5.4e-05 22.5 0.9 0.0034 16.8 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBY22898.1 - 0.0029 17.4 4.0 0.69 9.8 0.2 4.0 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_11 PF08976.11 CBY22898.1 - 0.094 13.6 0.0 0.16 12.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain TRP PF06011.12 CBY22899.1 - 0.0086 14.8 0.8 0.0094 14.7 0.8 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF5643 PF18705.1 CBY22899.1 - 0.028 14.4 0.9 0.039 13.9 0.8 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5643) Orf78 PF06024.12 CBY22899.1 - 0.073 13.4 0.7 0.095 13.0 0.7 1.4 1 1 0 1 1 1 0 Orf78 (ac78) SARAF PF06682.12 CBY22899.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Lysyl_oxidase PF01186.17 CBY22900.1 - 1.3e-89 299.3 2.7 1.3e-89 299.3 2.7 1.9 2 0 0 2 2 2 1 Lysyl oxidase SRCR PF00530.18 CBY22900.1 - 2.3e-80 265.5 31.7 1.2e-23 83.5 1.9 5.7 5 1 1 6 6 6 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 CBY22900.1 - 5.4e-28 97.4 17.3 4.5e-10 39.9 0.6 5.1 4 2 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 CBY22900.1 - 7.2e-11 42.6 3.9 0.17 12.4 0.0 4.8 4 1 0 4 4 4 4 Hepsin, SRCR domain DUF2196 PF09962.9 CBY22900.1 - 0.08 12.9 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2196) TauD PF02668.16 CBY22901.1 - 7.2e-30 104.7 0.0 1e-29 104.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 CBY22901.1 - 2.1e-05 23.8 0.0 3.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 CsiD UnbV_ASPIC PF07593.12 CBY22901.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ASPIC and UnbV MBD PF01429.19 CBY22905.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain zf-NPL4 PF05020.15 CBY22905.1 - 0.065 13.4 0.7 0.082 13.1 0.7 1.2 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region PI_PP_I PF18363.1 CBY22905.1 - 0.082 13.1 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain TPR_1 PF00515.28 CBY22906.1 - 8.1e-30 101.4 16.2 9e-08 31.6 0.0 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 CBY22906.1 - 1.1e-28 96.9 14.4 6.2e-06 25.9 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 CBY22906.1 - 8.8e-23 78.6 10.5 0.0016 18.5 0.0 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 CBY22906.1 - 3.5e-19 68.2 3.9 5.6e-07 29.1 0.0 6.5 4 2 4 8 8 7 4 TPR repeat TPR_14 PF13428.6 CBY22906.1 - 1.5e-18 65.9 4.1 0.041 14.7 0.0 9.6 7 1 3 10 10 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY22906.1 - 2.9e-17 62.7 18.4 5e-09 36.3 0.1 4.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY22906.1 - 4.5e-17 62.3 1.3 9.4e-05 22.8 0.4 5.7 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY22906.1 - 2.7e-16 59.9 0.8 7e-05 23.4 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBY22906.1 - 4.9e-16 57.9 10.4 7.2e-05 22.9 0.5 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY22906.1 - 5e-11 41.8 0.7 0.91 9.7 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY22906.1 - 5.2e-11 42.7 15.9 4.2e-05 23.7 0.0 7.3 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 CBY22906.1 - 4.9e-07 29.8 0.0 0.0013 18.8 0.0 4.2 4 1 2 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.8 CBY22906.1 - 9.6e-07 28.1 0.7 0.00077 18.5 0.3 3.0 1 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 CBY22906.1 - 5.3e-06 25.9 3.2 6.2e-05 22.3 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY22906.1 - 1.8e-05 25.1 5.0 11 6.9 0.0 8.4 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF3808 PF10300.9 CBY22906.1 - 0.00038 19.3 0.4 0.0011 17.7 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) HrpB1_HrpK PF09613.10 CBY22906.1 - 0.0012 18.4 0.0 0.027 14.1 0.0 2.5 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 CBY22906.1 - 0.0013 18.2 1.9 0.51 9.7 0.1 3.6 2 1 2 4 4 4 1 MalT-like TPR region DUF4919 PF16266.5 CBY22906.1 - 0.0017 18.3 0.9 0.26 11.2 0.1 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4919) TPR_10 PF13374.6 CBY22906.1 - 0.0098 15.7 1.1 73 3.4 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF627 PF04781.12 CBY22906.1 - 0.01 15.8 0.7 0.72 9.9 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF627) ChAPs PF09295.10 CBY22906.1 - 0.017 14.1 0.1 0.83 8.6 0.0 2.7 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4248 PF14053.6 CBY22906.1 - 0.032 14.2 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) TPR_20 PF14561.6 CBY22906.1 - 0.058 13.7 1.8 0.61 10.5 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CBY22906.1 - 0.87 9.6 3.8 1.2 9.1 0.7 2.8 3 1 1 4 4 3 0 Putative TPR-like repeat RCC1 PF00415.18 CBY22907.1 - 7.9e-29 100.1 6.1 0.0027 18.3 0.0 8.8 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY22907.1 - 0.00091 19.0 33.7 0.26 11.2 0.4 8.9 9 1 0 9 9 9 4 Regulator of chromosome condensation (RCC1) repeat Motile_Sperm PF00635.26 CBY22908.1 - 4e-26 91.0 1.4 9.4e-26 89.8 0.6 2.0 2 0 0 2 2 2 1 MSP (Major sperm protein) domain FlxA PF14282.6 CBY22908.1 - 0.0046 16.9 0.6 0.0046 16.9 0.6 2.2 2 0 0 2 2 2 1 FlxA-like protein PEP-utilisers_N PF05524.13 CBY22908.1 - 0.024 14.8 1.1 0.034 14.3 0.5 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal TIG_plexin PF17960.1 CBY22908.1 - 0.027 14.5 0.1 0.1 12.6 0.1 1.9 1 1 0 1 1 1 0 TIG domain Neur_chan_memb PF02932.16 CBY22908.1 - 0.051 13.6 1.3 0.065 13.3 1.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LapA_dom PF06305.11 CBY22908.1 - 0.64 9.9 2.1 1.7 8.5 0.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain NARP1 PF12569.8 CBY22908.1 - 0.97 8.3 11.1 1.2 7.9 11.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cupin_8 PF13621.6 CBY22909.1 - 1.2e-59 202.1 0.1 1.5e-59 201.7 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CBY22909.1 - 2.8e-05 24.5 0.0 9.7e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CBY22909.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein EcoRII-C PF09019.11 CBY22910.1 - 0.0078 16.3 0.3 0.063 13.4 0.1 2.2 2 1 0 2 2 2 1 EcoRII C terminal DUF5499 PF17603.2 CBY22910.1 - 0.041 14.5 0.1 7.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5499) His_Phos_2 PF00328.22 CBY22911.1 - 4.6e-117 391.6 0.1 6e-117 391.2 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CBY22911.1 - 2e-38 130.4 0.5 4.9e-38 129.2 0.5 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CBY22911.1 - 0.00064 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CBY22911.1 - 0.059 13.4 0.0 9.7 6.2 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain RWD PF05773.22 CBY22912.1 - 7.8e-21 74.5 1.3 7.8e-21 74.5 1.3 1.8 2 0 0 2 2 2 1 RWD domain PBECR1 PF18809.1 CBY22912.1 - 0.033 14.9 0.3 0.18 12.5 0.3 2.2 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 DUF4477 PF14780.6 CBY22913.1 - 0.097 12.3 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) YebO PF13974.6 CBY22913.1 - 0.37 10.9 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 YebO-like protein DEAD PF00270.29 CBY22914.1 - 1.7e-32 112.6 0.0 3.1e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY22914.1 - 2.7e-22 79.2 0.1 2.5e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY22914.1 - 6.7e-12 45.7 0.0 3.8e-11 43.3 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBY22914.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 CBY22914.1 - 0.052 12.8 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 CBY22914.1 - 0.067 13.5 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain HTH_Tnp_IS630 PF01710.16 CBY22915.1 - 0.013 15.6 0.1 0.013 15.6 0.1 2.4 2 1 0 2 2 2 0 Transposase Ras PF00071.22 CBY22916.1 - 5.9e-57 191.8 0.1 6.9e-57 191.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY22916.1 - 6.2e-35 120.0 0.0 1e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY22916.1 - 4e-16 59.0 0.0 4.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY22916.1 - 2.3e-07 30.9 0.0 0.0077 16.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY22916.1 - 1.7e-06 27.7 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY22916.1 - 2e-06 27.4 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY22916.1 - 6.5e-06 26.2 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CBY22916.1 - 0.0032 17.5 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 CBY22916.1 - 0.0072 16.7 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 CBY22916.1 - 0.023 14.1 0.2 0.042 13.3 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CBY22916.1 - 0.028 13.9 0.0 0.074 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CBY22916.1 - 0.046 13.5 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CBY22916.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 CBY22916.1 - 0.068 12.3 0.0 0.96 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CBY22916.1 - 0.15 12.6 0.2 0.27 11.7 0.2 1.8 1 1 0 1 1 1 0 ABC transporter DUF4023 PF13215.6 CBY22916.1 - 0.53 10.3 4.7 0.93 9.5 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) 5-nucleotidase PF06189.12 CBY22917.1 - 1.4e-97 325.8 0.0 1.8e-97 325.5 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase Acid_PPase PF12689.7 CBY22917.1 - 0.042 13.7 0.0 0.24 11.2 0.0 2.1 2 1 0 2 2 2 0 Acid Phosphatase RRM_1 PF00076.22 CBY22918.1 - 1.9e-07 30.8 0.0 4.6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPATA6 PF14909.6 CBY22919.1 - 8.4e-44 149.1 0.0 1.6e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 DUF1654 PF07867.11 CBY22919.1 - 0.064 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) DUF5584 PF17822.1 CBY22920.1 - 2.9e-07 30.2 0.1 4.1e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5584) Atx10homo_assoc PF09759.9 CBY22920.1 - 0.00095 19.1 0.4 0.0026 17.7 0.4 1.7 1 1 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain INTS5_N PF14837.6 CBY22920.1 - 0.063 12.9 0.5 0.087 12.4 0.1 1.5 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus DUF3638 PF12340.8 CBY22920.1 - 0.085 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) FtsK_alpha PF17854.1 CBY22920.1 - 0.15 12.2 0.1 0.44 10.7 0.0 1.7 1 1 1 2 2 2 0 FtsK alpha domain Glyco_hydro_47 PF01532.20 CBY22922.1 - 2.5e-128 428.8 2.5 3.3e-128 428.5 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FapA PF03961.13 CBY22922.1 - 0.22 10.1 2.1 0.32 9.5 2.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1003 PF06210.11 CBY22922.1 - 0.24 11.5 0.8 0.53 10.4 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) LRR_8 PF13855.6 CBY22926.1 - 2.3e-38 129.8 17.5 4.7e-15 55.1 2.2 4.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY22926.1 - 9.1e-16 57.7 12.7 1.1e-06 28.9 2.3 5.4 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY22926.1 - 7.8e-11 42.0 0.0 5.4e-10 39.3 0.0 2.3 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY22926.1 - 2.6e-07 30.3 1.1 6.3e-05 22.6 0.5 2.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CBY22926.1 - 2.8e-07 30.1 14.9 0.0087 16.5 0.5 6.8 7 0 0 7 7 7 2 Leucine Rich Repeat CBP_BcsR PF10945.8 CBY22926.1 - 0.057 12.9 0.2 5.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR LRR_6 PF13516.6 CBY22926.1 - 0.14 12.3 16.0 0.48 10.6 0.3 5.6 6 0 0 6 6 6 0 Leucine Rich repeat Tachykinin PF02202.16 CBY22926.1 - 0.27 11.2 0.7 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Tachykinin family AA_permease PF00324.21 CBY22928.1 - 5.1e-53 180.3 43.7 1.6e-33 116.0 11.6 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 CBY22928.1 - 6.5e-28 97.9 0.1 2.7e-21 76.1 0.1 2.8 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease_2 PF13520.6 CBY22928.1 - 6.2e-16 58.2 13.2 6.2e-16 58.2 13.2 2.2 2 0 0 2 2 2 1 Amino acid permease DUF3048_C PF17479.2 CBY22928.1 - 0.014 15.8 0.0 0.047 14.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain YccV-like PF08755.11 CBY22929.1 - 0.015 15.8 0.0 0.036 14.6 0.0 1.7 1 1 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like MFS_1 PF07690.16 CBY22930.1 - 1.5e-31 109.7 26.4 9.7e-22 77.4 7.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY22930.1 - 1.5e-31 109.7 10.2 1.4e-26 93.4 1.1 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 CBY22930.1 - 7.4e-05 22.2 5.1 0.00018 21.0 5.1 1.7 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 CBY22930.1 - 0.0034 16.3 6.3 1.2 8.0 4.6 2.8 3 0 0 3 3 3 2 MFS_1 like family Linker_histone PF00538.19 CBY22931.1 - 9.2e-19 67.6 3.4 1.6e-18 66.8 0.0 2.2 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 CBY22931.1 - 0.16 12.1 53.4 3.2 7.8 53.4 2.1 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 TUDOR PF00567.24 CBY22932.1 - 4.2e-16 59.1 0.0 4.8e-06 26.6 0.0 4.5 4 0 0 4 4 4 3 Tudor domain RRM_1 PF00076.22 CBY22933.1 - 1.6e-11 43.8 0.0 1.7e-05 24.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glycos_transf_1 PF00534.20 CBY22934.1 - 2.5e-12 46.7 0.0 4.1e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBY22934.1 - 3.8e-10 40.3 0.0 5.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBY22934.1 - 0.00041 20.7 0.0 0.00074 19.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Apolipo_F PF15148.6 CBY22934.1 - 0.029 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein F DUF4160 PF13711.6 CBY22935.1 - 0.07 13.5 1.0 11 6.5 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4160) Pkinase PF00069.25 CBY22937.1 - 8.8e-140 464.5 0.4 5e-69 232.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22937.1 - 7.3e-77 258.1 0.1 8.4e-43 146.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CBY22937.1 - 5.2e-15 55.4 0.6 4.7e-10 39.2 0.2 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY22937.1 - 1.1e-09 38.0 0.0 0.00032 20.1 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 CBY22937.1 - 2.1e-09 36.7 0.0 7.6e-05 21.7 0.0 2.7 3 0 0 3 3 3 2 Fungal protein kinase FTA2 PF13095.6 CBY22937.1 - 1.2e-07 31.6 2.7 0.89 9.1 0.1 4.2 3 1 0 4 4 4 3 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CBY22937.1 - 4.1e-06 26.5 0.0 0.0069 15.9 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Pkinase_C PF00433.24 CBY22937.1 - 4.4e-06 27.3 0.3 1.1e-05 26.0 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CBY22937.1 - 5.3e-06 25.6 0.8 0.027 13.4 0.0 2.5 2 1 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 CBY22937.1 - 1.1e-05 25.5 0.0 0.12 12.2 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 CBY22937.1 - 0.0011 18.6 0.1 0.49 10.0 0.0 2.5 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 CBY22937.1 - 0.017 14.0 0.1 0.028 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CBY22937.1 - 0.019 14.5 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase DnaJ PF00226.31 CBY22938.1 - 2.8e-15 56.2 0.4 7.9e-15 54.7 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain Endotoxin_C2 PF18449.1 CBY22938.1 - 0.022 15.1 1.3 0.046 14.1 0.2 2.1 2 0 0 2 2 2 0 Delta endotoxin Muted PF14942.6 CBY22938.1 - 0.023 15.1 5.5 0.023 15.1 5.5 2.4 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Catalase-rel PF06628.12 CBY22938.1 - 0.049 13.9 0.1 1 9.7 0.0 2.8 2 0 0 2 2 2 0 Catalase-related immune-responsive Chitin_synth_1 PF01644.17 CBY22938.1 - 0.11 12.4 0.7 0.18 11.8 0.7 1.3 1 0 0 1 1 1 0 Chitin synthase Sod_Ni PF09055.11 CBY22938.1 - 0.53 10.9 8.5 1.6 9.3 3.8 2.4 1 1 0 2 2 2 0 Nickel-containing superoxide dismutase 4HB_MCP_1 PF12729.7 CBY22938.1 - 1.5 8.3 10.6 0.36 10.4 6.0 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction RNase_P_Rpp14 PF01900.19 CBY22939.1 - 1.6e-15 57.2 0.4 2.2e-15 56.7 0.4 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family DnaJ PF00226.31 CBY22940.1 - 1.6e-23 82.6 0.3 1.6e-23 82.6 0.3 2.4 2 0 0 2 2 2 1 DnaJ domain zf-C2H2 PF00096.26 CBY22940.1 - 0.0034 17.7 0.4 0.0078 16.6 0.4 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY22940.1 - 0.027 14.8 0.8 0.027 14.8 0.8 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBY22940.1 - 0.042 14.7 0.1 0.13 13.2 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Grg1 PF11034.8 CBY22941.1 - 8.4 6.7 9.7 0.18 12.0 0.8 2.6 3 0 0 3 3 3 0 Glucose-repressible protein Grg1 Hep_59 PF07052.11 CBY22942.1 - 2.7e-23 82.7 2.1 2.7e-23 82.7 2.1 2.9 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 LMBR1 PF04791.16 CBY22942.1 - 2 7.2 3.5 2.3 7.0 3.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ank_2 PF12796.7 CBY22943.1 - 1.4e-06 28.8 0.0 2.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY22943.1 - 2.9e-05 24.2 0.2 0.00011 22.4 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY22943.1 - 3.6e-05 24.2 0.2 0.00046 20.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY22943.1 - 0.00026 21.3 0.2 0.055 13.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CBY22943.1 - 0.03 14.8 0.6 0.54 11.0 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat LMBR1 PF04791.16 CBY22943.1 - 1.8 7.4 5.9 2.4 7.0 5.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Smg4_UPF3 PF03467.15 CBY22944.1 - 3.5e-44 150.9 3.8 3.5e-44 150.9 3.8 3.0 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 CBY22944.1 - 0.00014 21.6 0.0 0.00036 20.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spb1_C PF07780.12 CBY22945.1 - 2.9e-49 167.6 41.9 2.9e-49 167.6 41.9 4.1 1 1 2 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 CBY22945.1 - 1.2e-10 41.4 17.2 1.2e-10 41.4 17.2 4.8 2 1 4 6 6 6 1 Domain of unknown function (DUF3381) WD40 PF00400.32 CBY22946.1 - 8.3e-25 86.6 3.7 1.7e-05 25.5 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat CSTF1_dimer PF16699.5 CBY22946.1 - 1.4e-22 79.2 0.2 2.4e-22 78.5 0.2 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 CBY22946.1 - 7.4e-13 48.6 0.0 0.16 12.3 0.0 4.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CBY22946.1 - 7.8e-05 21.2 0.0 9.7e-05 20.9 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 CBY22946.1 - 0.00057 18.9 1.5 0.099 11.6 0.6 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CBY22946.1 - 0.0063 16.5 0.0 5.5 7.1 0.0 3.2 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region NPR2 PF06218.11 CBY22947.1 - 8.5e-40 136.8 0.8 5e-38 131.0 0.8 2.8 1 1 0 1 1 1 1 Nitrogen permease regulator 2 HTH_AraC PF00165.23 CBY22947.1 - 0.0016 18.5 0.0 0.005 16.9 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Afi1 PF07792.12 CBY22947.1 - 0.064 13.7 2.2 0.12 12.9 0.0 2.4 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Kelch_6 PF13964.6 CBY22948.1 - 1.5e-10 41.0 0.2 0.00019 21.6 0.1 2.6 2 1 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CBY22948.1 - 2.5e-09 36.9 0.4 0.00076 19.4 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CBY22948.1 - 2.9e-09 36.6 0.7 0.0047 16.9 0.4 2.9 2 1 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CBY22948.1 - 8.2e-09 34.9 0.2 8.5e-05 22.1 0.0 2.4 2 1 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY22948.1 - 8.6e-09 35.3 0.1 0.00078 19.4 0.0 2.4 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY22948.1 - 0.00067 19.9 3.1 1 9.7 0.4 3.6 3 1 0 3 3 3 2 Galactose oxidase, central domain KN_motif PF12075.8 CBY22949.1 - 1.3e-05 24.9 3.2 2.9e-05 23.8 3.2 1.6 1 1 0 1 1 1 1 KN motif Ank_2 PF12796.7 CBY22950.1 - 3.1e-23 82.2 2.0 1e-13 51.7 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY22950.1 - 1.1e-18 67.1 2.3 5.9e-07 29.6 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY22950.1 - 1.8e-16 60.2 4.2 4.9e-08 33.4 0.0 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY22950.1 - 6.9e-16 56.7 1.2 0.0062 17.0 0.0 4.9 5 0 0 5 5 4 3 Ankyrin repeat Ank PF00023.30 CBY22950.1 - 2e-15 56.4 0.3 0.00039 20.7 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Lectin_N PF03954.14 CBY22950.1 - 0.014 15.2 3.8 1.1 9.1 3.8 2.6 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain KASH_CCD PF14662.6 CBY22950.1 - 0.05 13.4 9.5 0.098 12.5 9.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 CBY22950.1 - 0.62 10.3 16.7 0.17 12.1 12.0 2.3 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 ABC_tran_CTD PF16326.5 CBY22950.1 - 2 8.7 7.8 3.3 8.0 1.6 3.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain BRE1 PF08647.11 CBY22950.1 - 2.1 8.5 10.2 1.7 8.8 6.5 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FlxA PF14282.6 CBY22950.1 - 2.4 8.2 11.1 4.9 7.2 10.3 1.9 1 1 0 1 1 1 0 FlxA-like protein PI3K_P85_iSH2 PF16454.5 CBY22950.1 - 3.5 7.2 12.1 1.7 8.3 7.4 2.5 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4200 PF13863.6 CBY22953.1 - 0.0029 18.0 5.2 0.0029 18.0 5.2 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Sulfotransfer_1 PF00685.27 CBY22953.1 - 0.017 14.6 0.6 0.028 13.9 0.6 1.2 1 0 0 1 1 1 0 Sulfotransferase domain PNP_UDP_1 PF01048.20 CBY22954.1 - 2.6e-26 92.3 0.4 3.3e-26 92.0 0.4 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily ABA_GPCR PF12430.8 CBY22955.1 - 4.1e-41 140.7 7.0 4.1e-41 140.7 7.0 1.6 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CBY22955.1 - 6.7e-24 83.8 0.0 1.8e-23 82.4 0.0 1.8 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Ribosomal_S8 PF00410.19 CBY22956.1 - 7.7e-12 45.3 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L3 PF00297.22 CBY22957.1 - 2.4e-165 550.0 9.7 2.7e-165 549.8 9.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DEAD PF00270.29 CBY22958.1 - 3.9e-45 153.8 0.0 8e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY22958.1 - 1.6e-28 99.3 0.0 1.3e-27 96.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY22958.1 - 4.6e-06 26.7 0.0 8.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBY22958.1 - 0.0016 17.8 0.0 0.0087 15.4 0.0 2.2 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Ras PF00071.22 CBY22959.1 - 1.5e-53 180.7 0.1 2e-53 180.3 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY22959.1 - 1.4e-32 112.4 0.1 2.7e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY22959.1 - 2.3e-13 50.0 0.0 3.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY22959.1 - 1.4e-05 24.7 0.0 3.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY22959.1 - 2.3e-05 23.9 0.0 4.2e-05 23.0 0.0 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY22959.1 - 0.00023 21.2 0.1 0.00096 19.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY22959.1 - 0.0014 18.5 0.0 0.72 9.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CBY22959.1 - 0.0036 16.8 0.0 0.0065 15.9 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CBY22959.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 CBY22959.1 - 0.053 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) FeoB_N PF02421.18 CBY22959.1 - 0.054 13.0 0.0 8.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B W2 PF02020.18 CBY22960.1 - 2.6e-13 49.9 3.1 2.6e-13 49.9 3.1 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon MIF4G PF02854.19 CBY22960.1 - 1.4e-12 47.7 0.2 2.8e-12 46.8 0.2 1.5 1 0 0 1 1 1 1 MIF4G domain ATP-synt_Z PF16594.5 CBY22961.1 - 0.035 13.6 0.3 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated FecCD PF01032.18 CBY22961.1 - 0.24 10.4 7.2 0.097 11.7 4.4 1.7 2 0 0 2 2 2 0 FecCD transport family DUF2070 PF09843.9 CBY22961.1 - 1.3 7.3 7.9 1.5 7.0 7.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) La PF05383.17 CBY22962.1 - 0.00024 21.1 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 La domain PAM2 PF07145.15 CBY22962.1 - 0.017 14.8 0.3 0.099 12.4 0.0 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region HECT PF00632.25 CBY22963.1 - 7.5e-86 288.4 0.0 9.4e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CBY22963.1 - 6.1e-15 55.0 7.7 1.9e-09 37.4 1.0 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.30 CBY22963.1 - 0.00015 22.0 0.0 0.00046 20.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain Ph1570 PF09638.10 CBY22963.1 - 0.19 11.5 0.1 23 4.8 0.1 2.3 2 0 0 2 2 2 0 Ph1570 protein Band_7 PF01145.25 CBY22964.1 - 1.5e-19 70.7 0.0 1.5e-19 70.7 0.0 2.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 CBY22964.1 - 1.6e-08 34.7 36.2 2.8e-07 30.8 17.6 4.3 2 2 1 3 3 3 2 Flotillin SpecificRecomb PF10136.9 CBY22964.1 - 1.8 6.7 9.6 3 6.1 9.6 1.3 1 0 0 1 1 1 0 Site-specific recombinase UPF0113_N PF17833.1 CBY22965.1 - 1.1e-29 102.9 0.4 1.6e-29 102.2 0.4 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CBY22965.1 - 3.8e-23 81.5 0.1 6.7e-23 80.7 0.1 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 CBY22965.1 - 0.00033 20.6 0.0 0.00086 19.2 0.0 1.7 2 0 0 2 2 2 1 PUA domain MCRS_N PF13325.6 CBY22966.1 - 1.1e-55 188.8 4.1 1.5e-55 188.3 4.1 1.2 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein FHA PF00498.26 CBY22966.1 - 0.0002 21.6 1.9 0.00056 20.2 0.2 2.3 2 0 0 2 2 2 1 FHA domain Cob_adeno_trans PF01923.18 CBY22966.1 - 0.5 10.5 2.2 2.9 8.0 0.3 2.3 1 1 0 2 2 2 0 Cobalamin adenosyltransferase Nucleoside_tran PF01733.18 CBY22967.1 - 1.2e-50 172.6 10.4 1.2e-50 172.6 10.4 1.6 2 0 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 CBY22967.1 - 2e-09 36.8 0.8 2e-09 36.8 0.8 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.15 CBY22967.1 - 0.0049 15.9 1.8 0.0049 15.9 1.8 3.0 4 0 0 4 4 4 1 PUCC protein DUF4813 PF16072.5 CBY22967.1 - 0.21 11.2 0.2 0.37 10.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Sugar_tr PF00083.24 CBY22967.1 - 2.8 6.7 29.1 0.15 10.9 2.3 3.1 3 1 0 3 3 3 0 Sugar (and other) transporter WD40 PF00400.32 CBY22968.1 - 1.3e-24 86.0 10.7 9.7e-06 26.2 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 CBY22968.1 - 0.00014 21.3 0.0 0.1 11.9 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 CBY22968.1 - 0.00057 20.1 0.7 0.64 10.4 0.1 4.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY22968.1 - 0.0066 15.2 1.0 2.2 6.9 0.1 2.7 2 1 0 3 3 3 2 Nucleoporin Nup120/160 ELYS-bb PF16687.5 CBY22968.1 - 0.019 13.6 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin DAGK_cat PF00781.24 CBY22969.1 - 2.1e-18 66.2 0.0 3.5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Xpo1 PF08389.12 CBY22970.1 - 4.8e-13 49.4 8.7 3.8e-12 46.5 1.7 3.9 3 2 0 3 3 3 2 Exportin 1-like protein CRM1_C PF08767.11 CBY22970.1 - 0.013 14.6 0.1 0.055 12.6 0.0 2.0 2 0 0 2 2 2 0 CRM1 C terminal Nitrate_red_del PF02613.15 CBY22970.1 - 0.03 14.4 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Nitrate reductase delta subunit DENN PF02141.21 CBY22972.1 - 4.3e-42 144.2 6.1 8.5e-42 143.2 6.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 CBY22972.1 - 2.3e-11 44.3 0.0 6.7e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 CBY22972.1 - 6.6e-08 32.4 0.3 1.8e-07 31.0 0.3 1.9 1 0 0 1 1 1 1 dDENN domain IU_nuc_hydro PF01156.19 CBY22973.1 - 1.1e-66 225.5 0.3 1.2e-66 225.3 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Collagen PF01391.18 CBY22974.1 - 2.1e-12 46.6 68.4 1.9e-06 27.5 12.8 3.0 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) REJ PF02010.15 CBY22975.1 - 4.5e-14 52.1 7.8 1.9e-07 30.3 0.7 3.1 1 1 1 3 3 3 2 REJ domain PKD_2 PF16407.5 CBY22975.1 - 2.9e-10 40.6 1.1 0.00094 19.4 0.0 4.2 2 2 2 4 4 4 2 PKD-like family He_PIG PF05345.12 CBY22975.1 - 3.6e-09 36.7 4.6 0.0035 17.5 1.0 4.4 4 0 0 4 4 4 3 Putative Ig domain Cadherin PF00028.17 CBY22975.1 - 3.6e-06 27.3 2.6 1.1 9.7 0.1 3.7 3 0 0 3 3 3 3 Cadherin domain DUF4625 PF15418.6 CBY22975.1 - 1.1e-05 25.7 0.2 0.14 12.4 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4625) PKD PF00801.20 CBY22975.1 - 3.4e-05 23.6 2.8 0.026 14.4 0.0 4.6 4 1 0 4 4 4 1 PKD domain hGDE_N PF14699.6 CBY22975.1 - 0.00064 19.8 0.0 0.22 11.7 0.0 3.3 4 0 0 4 4 4 1 N-terminal domain from the human glycogen debranching enzyme Y_Y_Y PF07495.13 CBY22975.1 - 0.0018 18.2 1.5 0.97 9.4 0.2 3.1 3 0 0 3 3 3 2 Y_Y_Y domain DUF5011 PF16403.5 CBY22975.1 - 0.095 12.8 7.7 3.1 8.0 0.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5011) Cadherin_5 PF17892.1 CBY22975.1 - 0.31 11.0 9.1 18 5.4 0.9 4.6 3 1 0 4 4 4 0 Cadherin-like domain DUF1964 PF09244.10 CBY22975.1 - 0.31 11.5 4.2 12 6.4 0.3 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1964) Galactosyl_T PF01762.21 CBY22976.1 - 1.1e-19 71.1 0.0 1.5e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 CBY22976.1 - 0.0015 18.0 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Zona_pellucida PF00100.23 CBY22978.1 - 1.8e-41 142.7 0.2 2.3e-41 142.3 0.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Laminin_EGF PF00053.24 CBY22978.1 - 0.023 14.8 1.9 0.023 14.8 1.9 2.4 2 0 0 2 2 2 0 Laminin EGF domain EGF_2 PF07974.13 CBY22978.1 - 0.079 13.3 1.0 0.079 13.3 1.0 2.4 2 0 0 2 2 2 0 EGF-like domain DUF555 PF04475.12 CBY22978.1 - 0.092 13.1 1.3 26 5.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF555) CUB PF00431.20 CBY22979.1 - 2.2e-09 37.6 0.0 4.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 CUB domain Pkinase PF00069.25 CBY22981.1 - 5.3e-27 94.8 0.1 7.9e-23 81.1 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22981.1 - 3.1e-14 52.9 1.4 6.1e-14 51.9 0.0 2.2 3 1 1 4 4 4 1 Protein tyrosine kinase POLO_box PF00659.18 CBY22981.1 - 0.00017 21.7 0.8 0.007 16.5 0.1 2.8 2 0 0 2 2 2 1 POLO box duplicated region Pkinase_fungal PF17667.1 CBY22981.1 - 0.00072 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY22981.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF971 PF06155.12 CBY22981.1 - 0.023 15.3 0.0 0.32 11.7 0.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF971) RIO1 PF01163.22 CBY22981.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CTP_transf_1 PF01148.20 CBY22982.1 - 1.7e-74 251.0 21.8 2.1e-74 250.6 21.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF373 PF04123.13 CBY22982.1 - 3.6 6.9 6.0 5.9 6.2 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Pkinase PF00069.25 CBY22983.1 - 5.3e-62 209.6 0.0 7.5e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY22983.1 - 6.6e-42 143.6 0.0 9.6e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CBY22983.1 - 5.2e-24 83.9 37.9 1.1e-13 50.8 9.7 2.6 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Haspin_kinase PF12330.8 CBY22983.1 - 9.1e-05 21.6 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY22983.1 - 0.00098 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like C1_2 PF03107.16 CBY22983.1 - 0.0094 16.2 2.8 0.0094 16.2 2.8 2.9 3 0 0 3 3 3 1 C1 domain Kdo PF06293.14 CBY22983.1 - 0.027 13.8 0.1 0.06 12.7 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY22983.1 - 0.17 11.8 0.5 1.5 8.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2318 PF10080.9 CBY22983.1 - 0.35 11.0 12.9 1.3 9.2 2.8 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Zf_RING PF16744.5 CBY22983.1 - 1 9.6 10.3 0.21 11.7 1.7 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger Anoctamin PF04547.12 CBY22984.1 - 4.7e-118 394.9 12.1 6.6e-118 394.4 12.1 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CBY22984.1 - 3.2e-34 118.6 8.9 2.5e-32 112.4 8.9 2.6 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin MRP-S24 PF14955.6 CBY22984.1 - 0.17 11.8 1.8 0.27 11.2 0.3 2.1 2 1 0 2 2 2 0 Mitochondrial ribosome subunit S24 Cyclin_N PF00134.23 CBY22985.1 - 1.7e-14 53.7 0.1 1.3e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 CBY22985.1 - 0.0042 17.1 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 CBY22985.1 - 0.0075 16.4 0.9 2.6 8.2 0.0 2.9 2 1 0 2 2 2 2 Cyclin, C-terminal domain DUF3263 PF11662.8 CBY22985.1 - 0.078 12.8 0.1 0.7 9.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3263) Pneumo_att_G PF05539.11 CBY22985.1 - 0.56 9.8 5.4 0.79 9.3 5.4 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PI3_PI4_kinase PF00454.27 CBY22988.1 - 3e-44 151.7 0.0 5.3e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CBY22988.1 - 5.1e-05 23.0 0.0 9.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 FATC domain NUDIX PF00293.28 CBY22989.1 - 2.5e-05 24.3 0.0 9.1e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 NUDIX domain Transglut_core PF01841.19 CBY22989.1 - 0.00019 21.9 0.0 0.00063 20.2 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily BNIP3 PF06553.12 CBY22989.1 - 5 6.7 7.2 2 8.0 1.6 2.5 2 0 0 2 2 2 0 BNIP3 zf-H2C2_2 PF13465.6 CBY22990.1 - 1.6e-06 28.2 1.9 1.6e-06 28.2 1.9 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 CBY22990.1 - 7.5e-06 26.1 13.3 0.00073 19.9 3.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY22990.1 - 0.00051 20.7 3.4 0.00051 20.7 3.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger HypA PF01155.19 CBY22990.1 - 0.44 10.6 2.8 15 5.6 2.8 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 CBY22990.1 - 1.1 9.6 10.3 0.099 13.0 1.4 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY22990.1 - 4 8.0 7.7 0.82 10.1 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.6 CBY22990.1 - 4.3 7.3 7.9 7 6.7 0.6 2.7 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 CBY22990.1 - 4.4 7.6 9.7 0.5 10.6 1.3 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 CBY22990.1 - 7.3 6.7 11.1 0.93 9.5 1.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-C2H2_12 PF18112.1 CBY22990.1 - 7.8 7.1 8.8 0.34 11.4 2.0 2.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Sema PF01403.19 CBY22992.1 - 1.5e-14 53.7 0.8 3.1e-14 52.6 0.8 1.4 1 0 0 1 1 1 1 Sema domain Toxin_23 PF08093.11 CBY22992.1 - 0.018 15.2 3.6 0.065 13.4 3.6 2.0 1 0 0 1 1 1 0 Magi 5 toxic peptide family RhoGAP PF00620.27 CBY22993.1 - 1.4e-24 86.6 0.0 3.4e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RhoGAP-FF1 PF16512.5 CBY22994.1 - 5e-06 27.1 2.3 2.8e-05 24.7 0.5 2.7 2 0 0 2 2 2 1 p190-A and -B Rho GAPs FF domain GTP_EFTU PF00009.27 CBY22994.1 - 0.0075 15.8 0.2 0.016 14.8 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 CBY22994.1 - 0.04 13.5 0.0 0.27 10.8 0.0 2.3 2 0 0 2 2 2 0 Ras family FF PF01846.19 CBY22994.1 - 0.05 13.8 0.1 0.18 12.0 0.1 2.0 1 0 0 1 1 1 0 FF domain NOG1 PF06858.14 CBY22994.1 - 0.052 13.3 0.4 0.11 12.3 0.4 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) DUF4390 PF14334.6 CBY22994.1 - 0.12 11.8 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) Sulfotransfer_1 PF00685.27 CBY22995.1 - 1.7e-22 80.2 0.2 6.8e-12 45.4 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY22995.1 - 5.5e-06 26.9 0.0 0.1 13.0 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family PMP22_Claudin PF00822.20 CBY22996.1 - 4.2e-17 62.5 7.2 3.7e-15 56.2 7.2 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY22996.1 - 0.0022 17.8 4.5 0.059 13.1 4.5 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 CBY22996.1 - 0.012 15.1 2.5 0.026 14.0 0.1 2.4 3 0 0 3 3 3 0 Clc-like Trypsin PF00089.26 CBY22997.1 - 4.3e-33 115.0 0.0 7.4e-33 114.2 0.0 1.4 1 1 0 1 1 1 1 Trypsin Wbp11 PF09429.10 CBY22998.1 - 3.2e-19 69.1 7.5 3.2e-19 69.1 7.5 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 Type_ISP_C PF18135.1 CBY22999.1 - 0.045 12.7 0.1 0.055 12.5 0.1 1.1 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain SAGA-Tad1 PF12767.7 CBY23000.1 - 4e-08 33.3 1.2 0.00018 21.3 1.0 2.2 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit KNTase_C PF07827.11 CBY23000.1 - 0.059 13.2 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 KNTase C-terminal domain DUF4720 PF15846.5 CBY23000.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) Type_ISP_C PF18135.1 CBY23001.1 - 0.046 12.7 0.1 0.055 12.5 0.1 1.1 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain SAGA-Tad1 PF12767.7 CBY23002.1 - 3.4e-08 33.5 1.2 0.00021 21.1 0.9 2.2 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit KNTase_C PF07827.11 CBY23002.1 - 0.053 13.3 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 KNTase C-terminal domain DUF4720 PF15846.5 CBY23002.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) Seipin PF06775.14 CBY23003.1 - 8.1e-06 26.1 0.0 1.4e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Sec8_exocyst PF04048.14 CBY23003.1 - 0.088 12.7 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Ank_2 PF12796.7 CBY23004.1 - 1.9e-23 82.9 11.2 4.3e-09 36.8 0.1 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY23004.1 - 1.4e-21 76.5 4.5 4.8e-06 27.0 0.3 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY23004.1 - 6.4e-19 67.8 7.8 8.7e-09 35.5 0.6 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY23004.1 - 1.2e-18 66.6 9.9 2e-05 24.8 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CBY23004.1 - 1.7e-13 49.4 8.2 0.032 14.8 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat fn3 PF00041.21 CBY23004.1 - 0.016 15.5 0.1 0.079 13.3 0.1 2.1 1 1 0 1 1 1 0 Fibronectin type III domain DUF5130 PF17174.4 CBY23004.1 - 0.034 14.4 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) ATP-synt_DE_N PF02823.16 CBY23005.1 - 6.4e-14 51.6 0.1 2e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain zf-CCCH PF00642.24 CBY23006.1 - 3.6e-12 45.9 16.7 2.2e-07 30.6 2.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBY23006.1 - 3.5e-07 30.9 2.9 0.012 16.3 0.2 2.3 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 CBY23006.1 - 3.1e-05 23.9 14.2 0.022 14.8 3.4 2.5 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 CBY23006.1 - 0.031 14.1 0.1 0.056 13.3 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY23006.1 - 0.06 13.4 0.4 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 CBY23006.1 - 0.31 11.3 6.0 3.6 7.8 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger containing family RRM_1 PF00076.22 CBY23007.1 - 7.8e-38 128.1 0.0 6.7e-16 57.9 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY23007.1 - 1.6e-11 44.2 0.3 0.00039 20.4 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif RRM_5 PF13893.6 CBY23007.1 - 0.0008 19.0 0.0 0.012 15.2 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CBY23007.1 - 0.0068 16.1 1.7 0.034 13.8 1.7 2.2 1 1 0 1 1 1 1 Ribonuclease B OB domain Limkain-b1 PF11608.8 CBY23007.1 - 0.0071 16.4 1.4 0.85 9.7 0.0 3.0 3 0 0 3 3 3 1 Limkain b1 DbpA PF03880.15 CBY23007.1 - 0.0075 16.2 0.2 0.37 10.8 0.1 2.6 3 0 0 3 3 3 1 DbpA RNA binding domain SDP_N PF12278.8 CBY23007.1 - 0.044 13.9 13.0 0.31 11.2 5.8 3.2 3 0 0 3 3 3 0 Sex determination protein N terminal Transformer PF06495.11 CBY23007.1 - 0.045 13.8 41.4 0.38 10.8 4.9 3.2 3 0 0 3 3 3 0 Fruit fly transformer protein SET_assoc PF11767.8 CBY23007.1 - 0.089 12.4 0.3 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated ATP-grasp PF02222.22 CBY23007.1 - 0.21 11.2 0.0 14 5.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain PRP38_assoc PF12871.7 CBY23007.1 - 1.1 9.9 62.9 1.2 9.8 28.1 3.7 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF4504 PF14953.6 CBY23008.1 - 3.7e-09 36.4 0.1 7e-09 35.5 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4504) dsrm PF00035.26 CBY23009.1 - 0.0014 19.3 2.9 0.0051 17.5 0.0 3.0 3 0 0 3 3 3 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 CBY23009.1 - 0.047 13.9 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF1366 PF07104.11 CBY23009.1 - 0.55 9.9 2.9 1.7 8.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) F5_F8_type_C PF00754.25 CBY23010.1 - 7e-08 32.6 0.2 9.3e-08 32.2 0.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain 7tm_2 PF00002.24 CBY23011.1 - 2.6e-48 164.4 16.1 5.8e-48 163.3 16.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 CBY23011.1 - 9.3e-16 58.1 5.8 2.9e-15 56.5 5.8 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Gal_Lectin PF02140.18 CBY23011.1 - 6.3e-09 36.2 0.2 3.2e-08 33.9 0.1 2.3 2 0 0 2 2 2 1 Galactose binding lectin domain Cadherin_3 PF16184.5 CBY23014.1 - 6.9e-54 180.6 13.4 8.7e-12 45.0 0.0 9.2 8 1 1 9 9 9 7 Cadherin-like Lectin_C PF00059.21 CBY23014.1 - 1.3e-15 58.0 1.3 3.2e-15 56.8 1.3 1.7 1 0 0 1 1 1 1 Lectin C-type domain Calx-beta PF03160.14 CBY23014.1 - 4.1e-05 23.7 1.9 0.00062 19.9 0.0 3.1 3 0 0 3 3 3 1 Calx-beta domain Big_9 PF17963.1 CBY23014.1 - 0.55 11.0 9.1 63 4.4 0.0 6.3 6 1 0 6 6 6 0 Bacterial Ig domain Cadherin_3 PF16184.5 CBY23015.1 - 1.6e-05 24.9 0.0 0.00011 22.2 0.0 2.1 3 0 0 3 3 3 1 Cadherin-like Cadherin_3 PF16184.5 CBY23016.1 - 7.2e-49 164.4 0.0 4.4e-17 62.1 0.0 3.8 4 0 0 4 4 4 3 Cadherin-like Connexin PF00029.19 CBY23017.1 - 2.5e-77 259.8 5.3 1.1e-76 257.7 5.3 1.8 1 1 0 1 1 1 1 Connexin TetR_C_13 PF16925.5 CBY23018.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AA_permease_2 PF13520.6 CBY23020.1 - 4.1e-42 144.5 24.5 4.1e-42 144.5 24.5 2.1 1 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 CBY23020.1 - 6e-31 107.6 28.2 6e-31 107.6 28.2 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 CBY23020.1 - 1.6e-14 53.7 10.3 1.6e-14 53.7 10.3 3.1 3 0 0 3 3 3 1 C-terminus of AA_permease MAS20 PF02064.15 CBY23020.1 - 0.045 13.9 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor Fe_hyd_lg_C PF02906.14 CBY23021.1 - 3e-33 115.5 0.0 1.1e-31 110.4 0.0 2.2 2 0 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain EF-hand_6 PF13405.6 CBY23022.1 - 1.9e-13 49.1 5.7 0.00058 19.6 0.0 4.9 3 1 2 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 CBY23022.1 - 3.5e-13 48.1 6.7 0.00028 20.2 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 CBY23022.1 - 1.1e-11 45.0 1.2 1.5e-06 28.6 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY23022.1 - 3.6e-10 39.5 1.9 0.00023 21.0 0.1 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CBY23022.1 - 0.00013 22.3 0.0 0.7 10.3 0.0 2.5 2 1 1 3 3 3 2 EF-hand domain FlgD PF03963.14 CBY23022.1 - 0.0035 17.6 0.2 0.048 14.0 0.1 2.2 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region UPF0154 PF03672.13 CBY23022.1 - 0.009 16.0 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.6 CBY23022.1 - 0.015 14.8 3.3 0.61 9.7 0.0 3.9 4 0 0 4 4 4 0 EF hand AA_permease PF00324.21 CBY23023.1 - 7.8e-43 146.8 32.7 7.8e-43 146.8 32.7 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 CBY23023.1 - 4e-25 88.5 34.2 4e-25 88.5 34.2 1.9 2 0 0 2 2 2 1 Amino acid permease COesterase PF00135.28 CBY23024.1 - 8.8e-79 265.7 0.0 8e-76 255.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY23024.1 - 0.00077 19.4 0.0 0.0082 16.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY23024.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Methyltransf_16 PF10294.9 CBY23025.1 - 3.1e-16 59.6 0.0 4.4e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 CBY23025.1 - 0.00027 20.7 0.1 0.00044 20.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY23025.1 - 0.0067 17.1 0.2 0.015 16.0 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain EF1_GNE PF00736.19 CBY23026.1 - 5.4e-33 113.0 1.4 5.4e-33 113.0 1.4 1.5 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CBY23026.1 - 3.4e-14 53.0 5.8 3.4e-14 53.0 5.8 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.12 CBY23026.1 - 0.0041 16.9 2.6 0.0053 16.5 2.6 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MRP-L46 PF11788.8 CBY23027.1 - 0.0023 18.6 0.0 0.0033 18.1 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Flp1_like PF16982.5 CBY23027.1 - 0.033 13.6 0.5 0.052 12.9 0.5 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Y_phosphatase PF00102.27 CBY23028.1 - 1.9e-30 106.2 0.0 1.9e-30 106.2 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase ALIX_LYPXL_bnd PF13949.6 CBY23028.1 - 3.3e-14 52.9 11.7 3.3e-14 52.9 11.7 2.8 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV Pkinase PF00069.25 CBY23029.1 - 9.2e-25 87.5 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23029.1 - 3.1e-13 49.6 0.0 3.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY23029.1 - 4.3e-10 38.9 0.1 5.3e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY23029.1 - 0.083 12.8 0.1 0.27 11.1 0.1 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Baculo_PEP_C PF04513.12 CBY23030.1 - 0.36 10.9 2.2 0.65 10.0 2.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_1 PF00076.22 CBY23031.1 - 0.0035 17.1 0.1 0.0095 15.7 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY23031.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif F-actin_cap_A PF01267.17 CBY23032.1 - 3.4e-88 295.5 0.0 3.8e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.17 CBY23032.1 - 0.004 16.8 0.7 0.0065 16.1 0.7 1.3 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Methyltr_RsmF_N PF17125.5 CBY23032.1 - 0.047 14.2 0.1 3.1 8.4 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF P_proprotein PF01483.20 CBY23032.1 - 0.072 13.1 0.1 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Proprotein convertase P-domain Gam PF06064.11 CBY23033.1 - 0.063 13.5 0.2 2.8 8.2 0.1 2.0 1 1 1 2 2 2 0 Host-nuclease inhibitor protein Gam RRM_1 PF00076.22 CBY23034.1 - 9e-32 108.7 0.0 1.1e-13 50.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CBY23034.1 - 9.2e-06 25.6 0.2 2.3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 SPOC domain DUF3330 PF11809.8 CBY23034.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) KxDL PF10241.9 CBY23035.1 - 1.4e-17 63.8 1.0 1.8e-17 63.4 1.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4515 PF14988.6 CBY23035.1 - 0.011 15.6 0.4 0.015 15.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) MORN PF02493.20 CBY23036.1 - 4.8e-27 92.2 46.3 7.6e-07 28.7 1.9 7.8 8 1 0 8 8 8 6 MORN repeat DUF3048_C PF17479.2 CBY23036.1 - 0.01 16.2 11.9 0.89 10.0 0.5 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain Trp_halogenase PF04820.14 CBY23037.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF4728 PF15860.5 CBY23039.1 - 5.5 7.7 12.9 0.31 11.7 7.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) DUF2207 PF09972.9 CBY23039.1 - 7.8 5.1 8.9 44 2.7 8.9 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) NYD-SP28 PF14772.6 CBY23040.1 - 5.9e-25 87.2 9.5 5.9e-25 87.2 9.5 5.6 4 1 2 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 CBY23040.1 - 7.2e-19 67.7 3.3 7.2e-19 67.7 3.3 4.4 4 1 1 5 5 5 1 Sperm tail C-terminal domain DUF3540 PF12059.8 CBY23040.1 - 0.034 14.0 0.5 0.034 14.0 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3540) Crystall PF00030.19 CBY23041.1 - 5.3e-11 42.6 0.0 8.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin IL4_i_Ig PF18258.1 CBY23041.1 - 0.19 12.0 0.0 0.25 11.6 0.0 1.4 1 1 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain TACC_C PF05010.14 CBY23043.1 - 1e-27 97.3 17.0 1.1e-27 97.1 17.0 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FPP PF05911.11 CBY23043.1 - 0.0077 14.5 15.0 0.0089 14.3 15.0 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 CBY23043.1 - 0.0079 15.5 6.9 0.0079 15.5 6.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) CDPS PF16715.5 CBY23043.1 - 0.01 15.5 7.7 0.01 15.5 4.5 1.9 1 1 1 2 2 2 0 Cyclodipeptide synthase DUF3630 PF12305.8 CBY23043.1 - 0.018 15.1 0.6 0.038 14.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) CCDC144C PF14915.6 CBY23043.1 - 0.072 12.2 16.8 0.012 14.7 12.5 1.7 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region TPR_MLP1_2 PF07926.12 CBY23043.1 - 0.072 13.2 21.4 0.057 13.5 7.0 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CBY23043.1 - 0.091 11.6 17.4 0.11 11.4 17.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 CBY23043.1 - 0.15 12.1 21.6 4.2 7.4 5.3 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.11 CBY23043.1 - 0.16 10.8 16.9 0.034 13.0 4.7 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HALZ PF02183.18 CBY23043.1 - 0.16 12.2 12.1 1.1 9.5 0.3 3.8 2 2 2 4 4 4 0 Homeobox associated leucine zipper KxDL PF10241.9 CBY23043.1 - 0.52 10.6 13.9 5 7.5 0.5 3.5 2 1 2 4 4 4 0 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 CBY23043.1 - 0.55 10.3 18.6 1.5 8.8 4.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 CBY23043.1 - 0.6 11.0 16.6 1.7e+02 3.2 16.6 2.6 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 CBY23043.1 - 0.62 10.2 6.1 0.66 10.2 5.0 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 CBY23043.1 - 0.81 10.4 12.6 4.9 7.9 1.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 CBY23043.1 - 1.1 9.6 16.9 0.92 9.9 5.7 2.5 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Nup54 PF13874.6 CBY23043.1 - 1.2 9.3 14.9 1.1 9.4 11.1 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Exonuc_VII_L PF02601.15 CBY23043.1 - 1.3 8.5 9.9 1.8 8.1 9.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-Q PF13094.6 CBY23043.1 - 1.6 8.9 17.3 3.6 7.7 17.3 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 CBY23043.1 - 2 8.9 25.2 0.31 11.6 9.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 CBY23043.1 - 2.5 8.2 16.3 12 6.0 16.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cluap1 PF10234.9 CBY23043.1 - 2.8 7.3 17.6 2.6 7.4 5.2 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 Jnk-SapK_ap_N PF09744.9 CBY23043.1 - 3.5 7.9 23.0 0.49 10.6 14.7 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 CBY23043.1 - 4.6 7.3 7.3 2.4 8.2 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 CBY23043.1 - 5 5.6 16.0 6.5 5.2 16.0 1.0 1 0 0 1 1 1 0 Macoilin family GAS PF13851.6 CBY23043.1 - 5 6.4 20.2 8.6 5.7 20.1 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 CBY23043.1 - 5.5 7.5 10.0 13 6.3 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 FAM76 PF16046.5 CBY23043.1 - 5.6 6.2 9.9 9.1 5.5 9.9 1.4 1 1 0 1 1 1 0 FAM76 protein Lectin_N PF03954.14 CBY23043.1 - 5.8 6.7 8.5 8.1 6.2 4.5 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain LMBR1 PF04791.16 CBY23043.1 - 7.8 5.3 7.6 9.5 5.0 7.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 CBY23043.1 - 9.1 5.5 13.5 39 3.5 13.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RINGv PF12906.7 CBY23044.1 - 9.1e-13 48.1 13.8 9.1e-13 48.1 13.8 2.6 3 0 0 3 3 3 1 RING-variant domain EGF_2 PF07974.13 CBY23044.1 - 0.00058 20.2 12.9 0.00058 20.2 12.9 2.6 2 0 0 2 2 2 1 EGF-like domain EGF_Tenascin PF18720.1 CBY23044.1 - 0.05 13.7 7.9 0.2 11.7 7.9 2.1 1 0 0 1 1 1 0 Tenascin EGF domain Sugar_tr PF00083.24 CBY23045.1 - 1.5e-25 90.0 19.8 2.2e-25 89.5 19.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY23045.1 - 1.8e-17 63.3 34.2 2.5e-17 62.9 34.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ThrE PF06738.12 CBY23045.1 - 6.2 6.1 20.1 2.7 7.3 8.7 2.8 2 1 1 3 3 3 0 Putative threonine/serine exporter Tup_N PF08581.10 CBY23046.1 - 0.091 13.1 20.7 0.21 11.9 3.0 4.3 3 2 2 5 5 5 0 Tup N-terminal LPP PF04728.13 CBY23046.1 - 0.19 12.2 0.2 0.19 12.2 0.2 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper ERM PF00769.19 CBY23046.1 - 0.47 10.2 33.6 0.045 13.5 29.0 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family MtrG PF04210.13 CBY23046.1 - 2.3 8.1 4.2 8.6 6.3 0.1 3.1 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G WD40_alt PF14077.6 CBY23046.1 - 8.5 6.3 9.9 0.13 12.1 1.0 2.6 3 0 0 3 3 3 0 Alternative WD40 repeat motif Nas2_N PF18265.1 CBY23047.1 - 1.7e-22 79.1 1.7 3.2e-22 78.3 1.7 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 CBY23047.1 - 1.8e-07 30.9 0.0 2.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY23047.1 - 6.5e-07 29.6 0.1 1.5e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CBY23047.1 - 0.0065 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain CPP1-like PF11833.8 CBY23047.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Inositol_P PF00459.25 CBY23048.1 - 3e-35 122.1 0.2 3.7e-35 121.8 0.2 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1754 PF08555.10 CBY23049.1 - 7.7e-05 23.4 16.2 7.7e-05 23.4 16.2 2.5 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) AP3D1 PF06375.11 CBY23049.1 - 0.11 12.7 9.5 0.16 12.2 4.7 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 HA2 PF04408.23 CBY23051.1 - 2.4e-21 76.1 0.0 8.6e-21 74.3 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBY23051.1 - 6.5e-20 71.3 0.0 1.6e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBY23051.1 - 9.8e-14 51.6 0.0 2.1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY23051.1 - 0.025 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase GRIP PF01465.20 CBY23052.1 - 6.4e-10 38.8 0.0 2.1e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 GRIP domain Nup54 PF13874.6 CBY23052.1 - 0.00034 20.7 8.6 0.00034 20.7 8.6 10.1 3 2 6 9 9 9 2 Nucleoporin complex subunit 54 Sec34 PF04136.15 CBY23052.1 - 0.0019 18.1 3.7 0.0019 18.1 3.7 12.6 4 3 6 12 12 12 3 Sec34-like family DUF3450 PF11932.8 CBY23052.1 - 0.0039 16.5 9.1 0.0039 16.5 9.1 11.7 2 2 7 11 11 11 5 Protein of unknown function (DUF3450) Aminotran_1_2 PF00155.21 CBY23053.1 - 1.1e-83 281.4 0.0 1.3e-83 281.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CBY23053.1 - 0.039 12.8 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase RRM_1 PF00076.22 CBY23054.1 - 4e-14 52.2 0.0 6.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY23054.1 - 5.6e-06 26.4 0.0 1.7e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 CBY23055.1 - 4.7e-10 39.2 0.1 1e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tna_leader PF08053.11 CBY23055.1 - 0.21 11.6 0.4 0.52 10.4 0.4 1.6 1 0 0 1 1 1 0 Tryptophanase operon leader peptide Ctr PF04145.15 CBY23056.1 - 1.3e-28 100.4 1.3 1.6e-28 100.2 1.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FH2 PF02181.23 CBY23057.1 - 8.5e-78 262.1 13.6 8.5e-78 262.1 13.6 2.5 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CBY23057.1 - 1.5e-28 99.8 4.3 1.5e-28 99.8 4.3 2.9 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CBY23057.1 - 0.00045 19.8 0.4 0.00045 19.8 0.4 4.1 5 0 0 5 5 5 1 Diaphanous GTPase-binding Domain AP-5_subunit_s1 PF15001.6 CBY23057.1 - 0.63 10.0 6.3 5.1 7.0 3.3 2.9 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 NPV_P10 PF05531.12 CBY23057.1 - 2 8.9 6.1 20 5.8 0.8 3.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tim29 PF10171.9 CBY23058.1 - 2.7e-20 72.5 0.3 3.7e-20 72.1 0.3 1.3 1 0 0 1 1 1 1 Translocase of the Inner Mitochondrial membrane 29 Flavodoxin_5 PF12724.7 CBY23058.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain zf-C2H2 PF00096.26 CBY23059.1 - 2e-12 46.8 21.7 0.00012 22.3 1.1 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY23059.1 - 7.6e-12 45.0 20.2 0.00079 20.1 0.4 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY23059.1 - 5.6e-06 26.6 12.2 0.0043 17.4 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBY23059.1 - 2.1e-05 24.7 21.3 0.022 15.2 0.4 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY23059.1 - 2.5e-05 24.4 16.4 0.0065 16.7 0.2 3.6 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY23059.1 - 0.00042 20.6 16.9 0.47 10.8 0.5 3.2 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CBY23059.1 - 0.00044 20.2 7.0 0.017 15.1 0.4 3.2 3 1 0 3 3 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBY23059.1 - 0.0055 17.0 14.4 0.17 12.2 6.9 2.7 1 1 2 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding DUF1104 PF06518.11 CBY23059.1 - 0.014 15.8 5.2 0.11 12.9 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) zf-C2H2_11 PF16622.5 CBY23059.1 - 0.022 14.5 4.2 0.022 14.5 4.2 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type Fer4_9 PF13187.6 CBY23059.1 - 0.051 13.7 3.9 0.051 13.7 3.9 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain BolA PF01722.18 CBY23059.1 - 0.053 13.8 2.9 0.57 10.5 0.1 2.3 2 0 0 2 2 2 0 BolA-like protein HydF_tetramer PF18133.1 CBY23059.1 - 0.064 13.0 1.2 0.11 12.3 1.2 1.5 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain zf-BED PF02892.15 CBY23059.1 - 0.082 12.9 14.9 1.8 8.6 4.6 3.3 1 1 2 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.6 CBY23059.1 - 0.29 11.1 9.7 3.2 7.8 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 CBY23059.1 - 0.4 11.4 10.9 8 7.2 0.4 3.3 1 1 1 3 3 3 0 FOXP coiled-coil domain HNH PF01844.23 CBY23059.1 - 0.69 10.1 0.0 0.69 10.1 0.0 3.1 3 0 0 3 3 3 0 HNH endonuclease zf-CHCC PF10276.9 CBY23059.1 - 0.92 9.6 6.2 7.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger domain zf-C3HC4 PF00097.25 CBY23059.1 - 1 9.3 7.5 6.5 6.7 8.4 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 CBY23059.1 - 1.2 9.1 11.2 18 5.3 0.1 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Actin_micro PF17003.5 CBY23059.1 - 2.7 7.1 15.4 0.36 10.0 0.9 2.9 1 1 2 3 3 3 0 Putative actin-like family PHD_4 PF16866.5 CBY23059.1 - 4.9 7.3 11.0 7.8 6.7 4.1 2.3 1 1 0 2 2 2 0 PHD-finger DUF629 PF04780.12 CBY23059.1 - 5.2 5.5 17.1 0.4 9.2 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF629) CpXC PF14353.6 CBY23059.1 - 5.3 7.1 11.2 1.5 8.9 2.1 2.6 1 1 1 2 2 2 0 CpXC protein CrgA PF06781.12 CBY23060.1 - 0.39 10.8 3.3 0.25 11.4 1.0 1.9 2 0 0 2 2 2 0 Cell division protein CrgA Cg6151-P PF10233.9 CBY23060.1 - 2.1 8.7 12.7 8.6 6.7 12.6 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Nop14 PF04147.12 CBY23061.1 - 0.00086 17.7 15.7 0.001 17.4 15.7 1.2 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.13 CBY23061.1 - 0.11 12.5 14.2 0.18 11.7 14.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.6 CBY23062.1 - 7.4e-18 64.1 37.2 1.5e-06 28.3 1.4 6.5 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY23062.1 - 5.8e-14 51.7 51.9 1.2e-05 25.5 1.7 6.9 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY23062.1 - 1.8e-11 43.8 43.9 0.0019 18.9 1.3 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 CBY23062.1 - 5.1e-08 33.1 44.0 0.091 13.2 2.1 6.5 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY23062.1 - 9.3e-07 29.0 33.2 0.019 15.2 0.5 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 CBY23062.1 - 0.0015 18.3 4.5 0.016 15.0 0.0 2.6 1 1 1 2 2 2 1 GAGA factor zf-C2H2_11 PF16622.5 CBY23062.1 - 0.0067 16.2 0.5 0.0067 16.2 0.5 4.6 5 1 0 5 5 5 1 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 CBY23062.1 - 0.015 15.0 0.4 0.015 15.0 0.4 5.4 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 CBY23062.1 - 5.7 7.8 21.7 5.1 7.9 0.5 3.3 3 0 0 3 3 3 0 zinc-ribbon family zf-C2H2_2 PF12756.7 CBY23062.1 - 7 7.0 35.6 4.6 7.6 0.3 5.8 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Mpp10 PF04006.12 CBY23063.1 - 0.067 11.6 9.3 0.076 11.5 9.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Sushi PF00084.20 CBY23065.1 - 4.2e-08 33.6 17.4 1.1e-05 26.0 3.3 3.6 3 1 0 3 3 3 2 Sushi repeat (SCR repeat) Mid2 PF04478.12 CBY23065.1 - 0.002 18.0 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Vanabin-2 PF11437.8 CBY23065.1 - 1.4 9.1 15.5 0.061 13.5 7.3 2.2 2 0 0 2 2 2 0 Vanadium-binding protein 2 FGE-sulfatase PF03781.16 CBY23066.1 - 1.7e-74 250.7 3.4 1.9e-74 250.5 3.4 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 TRAM_LAG1_CLN8 PF03798.16 CBY23067.1 - 5.3e-40 137.3 34.2 7.1e-40 136.9 34.2 1.2 1 0 0 1 1 1 1 TLC domain MFS_1 PF07690.16 CBY23068.1 - 9.3e-12 44.5 25.0 9.3e-12 44.5 25.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.15 CBY23068.1 - 0.00068 18.7 0.2 0.00068 18.7 0.2 1.8 2 1 0 2 2 2 1 PUCC protein RRM_1 PF00076.22 CBY23069.1 - 1.6e-10 40.6 0.0 2.6e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.11 CBY23069.1 - 0.12 11.4 27.2 1.1 8.2 27.3 2.1 1 1 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DDHD PF02862.17 CBY23070.1 - 8.8e-44 150.3 0.0 1.9e-43 149.3 0.0 1.6 1 0 0 1 1 1 1 DDHD domain WWE PF02825.20 CBY23070.1 - 4e-08 33.7 0.0 7.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 WWE domain Sel1 PF08238.12 CBY23071.1 - 2.4e-11 43.9 21.8 0.17 12.6 0.0 6.8 7 0 0 7 7 7 5 Sel1 repeat TPR_12 PF13424.6 CBY23071.1 - 0.0078 16.5 17.8 0.038 14.3 1.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY23071.1 - 0.034 14.4 11.9 1.2 9.6 0.4 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBY23071.1 - 0.07 14.0 13.0 3.6 8.7 1.2 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY23071.1 - 1.4 9.7 14.1 35 5.3 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBY23071.1 - 2.3 8.8 12.5 11 6.6 2.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY23071.1 - 3.9 7.5 9.0 28 4.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat UBX PF00789.20 CBY23072.1 - 1.1e-13 51.1 0.0 3.9e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.6 CBY23072.1 - 0.15 12.5 2.5 0.21 12.0 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like domain Mitofilin PF09731.9 CBY23072.1 - 0.33 9.7 31.9 0.49 9.2 31.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LAP1C PF05609.12 CBY23072.1 - 1.3 8.1 19.7 1.7 7.6 19.7 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Atg14 PF10186.9 CBY23072.1 - 7.1 5.6 23.0 11 5.0 23.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Oxysterol_BP PF01237.18 CBY23073.1 - 8.8e-76 255.2 6.5 7.3e-74 248.8 6.5 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CBY23073.1 - 1.7e-07 31.7 0.2 4.2e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 CBY23073.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBY23073.1 - 0.0025 18.2 1.9 0.088 13.2 1.9 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain LRR_4 PF12799.7 CBY23074.1 - 4.7e-18 65.0 17.0 6.4e-05 23.2 0.1 5.3 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY23074.1 - 8e-10 38.3 16.6 0.00034 20.3 2.3 4.6 2 2 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 CBY23074.1 - 1.7e-09 37.4 12.2 7.1e-06 25.6 1.4 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CBY23074.1 - 0.0014 18.9 10.8 11 7.0 0.1 5.9 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY23074.1 - 0.32 11.2 3.9 19 5.6 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Isy1 PF06246.12 CBY23075.1 - 1.5e-89 300.0 9.8 1.7e-89 299.8 9.8 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DivIC PF04977.15 CBY23075.1 - 0.39 10.5 0.1 0.39 10.5 0.1 2.6 4 0 0 4 4 4 0 Septum formation initiator Ribosomal_L21p PF00829.21 CBY23076.1 - 1.4e-10 41.3 0.0 1.8e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Dehydrin PF00257.19 CBY23077.1 - 0.00072 20.1 3.7 0.00095 19.8 3.7 1.3 1 0 0 1 1 1 1 Dehydrin SR-25 PF10500.9 CBY23077.1 - 0.0074 15.9 12.8 0.011 15.3 12.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4588 PF15251.6 CBY23077.1 - 0.22 11.3 5.2 0.29 10.9 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) MRC1 PF09444.10 CBY23077.1 - 0.52 10.8 3.7 0.68 10.4 3.7 1.1 1 0 0 1 1 1 0 MRC1-like domain Med19 PF10278.9 CBY23077.1 - 1.1 9.2 8.6 1.4 8.8 8.6 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 O-FucT PF10250.9 CBY23078.1 - 7.9e-72 242.8 0.0 9.2e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Nop PF01798.18 CBY23079.1 - 4.8e-85 284.7 0.2 4.8e-85 284.7 0.2 2.3 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBY23079.1 - 2.4e-17 63.1 0.1 2.4e-17 63.1 0.1 3.2 3 1 0 3 3 3 1 NOP5NT (NUC127) domain TFIIF_alpha PF05793.12 CBY23079.1 - 7.3 5.1 50.7 23 3.4 49.4 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C2H2_4 PF13894.6 CBY23080.1 - 0.29 12.1 2.7 7 7.8 0.0 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger PBP1_TM PF14812.6 CBY23080.1 - 0.61 10.5 2.7 1.5 9.2 2.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2 PF00096.26 CBY23080.1 - 1 9.9 0.0 1 9.9 0.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 CBY23081.1 - 8.4e-32 107.9 48.5 2.9e-05 24.3 2.2 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY23081.1 - 2.1e-26 90.3 55.3 0.00029 21.4 3.0 7.9 8 0 0 8 8 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY23081.1 - 5.2e-17 61.4 40.3 3.2e-06 27.3 0.2 7.9 8 0 0 8 8 7 5 Zinc-finger double domain BTB PF00651.31 CBY23081.1 - 7.3e-17 61.6 0.3 2.1e-16 60.1 0.3 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_jaz PF12171.8 CBY23081.1 - 8e-17 61.1 37.5 0.0015 18.8 1.0 7.6 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY23081.1 - 2.5e-13 49.6 43.1 5.4e-05 23.1 0.2 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 CBY23081.1 - 2e-09 37.5 44.5 0.011 16.1 0.4 7.4 8 0 0 8 8 7 5 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CBY23081.1 - 4.1e-05 23.4 25.3 0.016 15.1 0.2 6.5 6 0 0 6 6 6 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 CBY23081.1 - 0.00021 21.5 28.0 0.00047 20.4 2.6 4.0 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CBY23081.1 - 0.012 16.0 40.8 1.7 9.0 1.3 6.8 2 1 5 7 7 6 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 CBY23081.1 - 0.012 16.0 1.5 0.012 16.0 1.5 3.2 2 2 1 3 3 3 0 zinc-finger-containing domain HalOD2 PF18547.1 CBY23081.1 - 0.026 14.4 0.2 0.026 14.4 0.2 4.2 4 1 0 4 4 4 0 Halobacterial output domain 2 zf-FCS PF06467.14 CBY23081.1 - 0.054 13.4 17.5 1.7 8.6 0.1 4.5 3 1 1 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_11 PF16622.5 CBY23081.1 - 0.53 10.1 25.6 2 8.3 0.0 6.8 6 1 0 6 6 6 0 zinc-finger C2H2-type Rpr2 PF04032.16 CBY23081.1 - 0.61 10.4 26.9 0.73 10.2 0.2 4.0 3 2 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_5 PF13909.6 CBY23081.1 - 1.6 8.5 35.9 0.13 12.1 1.2 5.5 6 1 0 6 6 5 0 C2H2-type zinc-finger domain CxC7 PF18866.1 CBY23081.1 - 2 8.6 7.9 0.9 9.7 0.1 3.9 4 0 0 4 4 4 0 CxC7 like cysteine cluster associated with KDZ transposases ADK_lid PF05191.14 CBY23081.1 - 2.2 8.3 11.1 55 3.9 0.9 5.2 4 2 0 4 4 4 0 Adenylate kinase, active site lid Elf1 PF05129.13 CBY23081.1 - 9.4 6.4 29.9 0.23 11.5 5.6 4.1 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like DNA_repr_REX1B PF14966.6 CBY23082.1 - 4e-09 37.0 4.2 4e-09 37.0 4.2 1.7 1 1 1 2 2 2 1 DNA repair REX1-B Syntaxin_2 PF14523.6 CBY23082.1 - 0.035 14.5 2.8 0.09 13.2 2.7 1.8 1 1 0 1 1 1 0 Syntaxin-like protein YcbB PF08664.10 CBY23082.1 - 0.035 14.1 3.2 0.037 14.1 0.1 1.9 1 1 1 2 2 2 0 YcbB domain HAUS6_N PF14661.6 CBY23082.1 - 0.22 11.1 5.3 0.94 9.0 4.8 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3347 PF11827.8 CBY23082.1 - 0.25 11.5 4.7 0.094 12.9 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF4852 PF16144.5 CBY23082.1 - 1.1 9.5 4.9 7.9 6.6 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4852) DnaJ PF00226.31 CBY23083.1 - 1.5e-12 47.4 0.7 3.9e-12 46.1 0.0 2.0 3 0 0 3 3 3 1 DnaJ domain RRM_1 PF00076.22 CBY23084.1 - 9.6e-07 28.5 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Neur_chan_memb PF02932.16 CBY23084.1 - 5.6 7.0 9.8 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cyclin_N PF00134.23 CBY23085.1 - 1.8e-14 53.6 0.6 6.9e-14 51.7 0.2 2.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CBY23085.1 - 4.4e-11 43.1 0.1 1.3e-10 41.5 0.1 1.8 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 CBY23085.1 - 0.0001 22.4 0.3 0.049 13.7 0.0 2.7 2 1 0 2 2 2 2 Cyclin, C-terminal domain Alg14 PF08660.11 CBY23086.1 - 2.2e-56 190.5 0.0 2.7e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_transf_28 PF03033.20 CBY23086.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain ATP_synth_reg PF14960.6 CBY23087.1 - 0.0026 17.2 0.3 0.0062 16.0 0.3 1.6 1 0 0 1 1 1 1 ATP synthase regulation SURF4 PF02077.15 CBY23088.1 - 1.7e-27 96.7 0.0 2e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 CBY23088.1 - 0.02 15.5 1.2 0.11 13.1 1.3 1.8 1 1 0 1 1 1 0 DoxX Fun_ATP-synt_8 PF05933.13 CBY23088.1 - 0.035 14.3 0.4 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Caerin_1 PF07440.12 CBY23088.1 - 0.59 10.3 0.2 0.59 10.3 0.2 1.9 3 0 0 3 3 3 0 Caerin 1 protein SURF4 PF02077.15 CBY23089.1 - 1.2e-55 189.0 5.0 1.3e-55 188.9 5.0 1.0 1 0 0 1 1 1 1 SURF4 family V_ATPase_I PF01496.19 CBY23090.1 - 2.1 6.2 5.2 2.3 6.0 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hexokinase_2 PF03727.16 CBY23091.1 - 4.4e-39 134.4 0.0 4.9e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CBY23092.1 - 2.3e-40 138.7 0.0 2.9e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase COG2 PF06148.11 CBY23092.1 - 0.061 13.4 0.2 0.27 11.3 0.1 2.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HupF_HypC PF01455.18 CBY23092.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 HupF/HypC family OGG_N PF07934.12 CBY23093.1 - 9.1e-16 58.0 0.1 2.8e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CBY23093.1 - 8.6e-12 45.5 0.0 1.9e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CBY23093.1 - 0.00021 21.0 0.0 0.0011 18.7 0.0 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif DUF2681 PF10883.8 CBY23093.1 - 0.0032 17.8 3.5 0.0076 16.6 3.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) HHH_5 PF14520.6 CBY23093.1 - 0.018 15.6 0.1 0.11 13.1 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 CBY23093.1 - 0.067 13.3 0.0 9.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Cauli_VI PF01693.16 CBY23094.1 - 2.8e-05 24.3 0.0 3.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Caulimovirus viroplasmin Ribosomal_L15e PF00827.17 CBY23095.1 - 1.5e-87 292.3 7.6 1.7e-87 292.1 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Crystall PF00030.19 CBY23095.1 - 0.064 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Ribosomal_L24e PF01246.20 CBY23096.1 - 5.9e-27 93.7 0.3 5.9e-27 93.7 0.3 2.1 2 1 2 4 4 4 1 Ribosomal protein L24e PRMT5_C PF17286.2 CBY23097.1 - 1.3e-30 106.5 0.1 1.6e-30 106.3 0.1 1.0 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5 PF05185.16 CBY23098.1 - 5.6e-61 205.4 0.1 8.5e-61 204.8 0.1 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 CBY23098.1 - 1.7e-30 106.1 0.0 2.4e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 CBY23098.1 - 1.3e-09 38.2 0.2 1.3e-09 38.2 0.2 1.6 2 0 0 2 2 2 1 PRMT5 oligomerisation domain Met_10 PF02475.16 CBY23098.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.14 CBY23098.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain zf-H2C2_2 PF13465.6 CBY23099.1 - 3e-20 71.7 54.8 6.5e-08 32.7 2.4 9.3 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2 PF00096.26 CBY23099.1 - 6.9e-19 67.2 68.4 0.0023 18.3 3.8 8.7 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY23099.1 - 3.2e-13 49.3 67.7 0.0036 18.0 0.5 8.9 8 0 0 8 8 8 7 C2H2-type zinc finger zf-BED PF02892.15 CBY23099.1 - 0.00011 22.2 34.7 0.25 11.4 3.7 5.8 3 1 1 5 5 5 3 BED zinc finger zf-Di19 PF05605.12 CBY23099.1 - 0.00013 22.2 39.4 0.0056 16.9 4.5 5.7 3 1 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding Actin_micro PF17003.5 CBY23099.1 - 0.0019 17.4 0.2 0.0019 17.4 0.2 4.7 2 1 1 3 3 2 1 Putative actin-like family GAGA PF09237.11 CBY23099.1 - 0.0027 17.5 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 GAGA factor zf-H2C2_5 PF13909.6 CBY23099.1 - 0.0037 17.0 5.4 0.0037 17.0 5.4 6.8 8 1 0 8 8 5 2 C2H2-type zinc-finger domain zf_UBZ PF18439.1 CBY23099.1 - 0.0053 16.3 0.4 0.0053 16.3 0.4 6.8 8 1 1 9 9 8 1 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 CBY23099.1 - 0.0066 16.7 39.3 0.42 11.0 1.9 7.8 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 CBY23099.1 - 0.17 12.0 0.1 0.17 12.0 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger domain HypA PF01155.19 CBY23099.1 - 0.22 11.5 18.9 0.57 10.2 1.0 4.5 2 1 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FIT1_2 PF17357.2 CBY23099.1 - 0.64 10.1 4.2 0.2 11.7 0.2 2.2 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 zf-Sec23_Sec24 PF04810.15 CBY23099.1 - 0.84 9.7 15.6 6.8 6.8 0.0 5.6 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger PknG_rubred PF16919.5 CBY23099.1 - 4.6 7.4 5.5 1.3 9.1 0.8 2.6 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain DNA_RNApol_7kD PF03604.13 CBY23099.1 - 4.9 6.9 10.8 1.2 8.9 0.0 3.7 4 0 0 4 4 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_15 PF17032.5 CBY23099.1 - 6.8 7.5 31.2 0.22 12.3 0.7 5.0 2 1 2 5 5 5 0 zinc-ribbon family zf-C2H2_8 PF15909.5 CBY23099.1 - 7.2 7.0 33.1 0.83 10.0 6.0 5.1 3 2 2 5 5 5 0 C2H2-type zinc ribbon MYCBPAP PF14646.6 CBY23100.1 - 6.3e-46 157.2 0.1 1e-45 156.5 0.1 1.4 1 0 0 1 1 1 1 MYCBP-associated protein family Nse5 PF08691.10 CBY23100.1 - 0.078 11.6 0.2 4.6 5.8 0.0 2.2 2 0 0 2 2 2 0 DNA repair proteins Nse5 and Nse6 DUF3987 PF13148.6 CBY23100.1 - 0.34 9.9 6.5 0.57 9.1 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Vasohibin PF14822.6 CBY23101.1 - 6.8e-95 316.9 0.1 8.6e-95 316.6 0.1 1.1 1 0 0 1 1 1 1 Vasohibin EcKinase PF02958.20 CBY23102.1 - 3.3e-15 56.2 0.0 7.6e-09 35.3 0.0 2.2 1 1 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 CBY23102.1 - 2.1e-10 41.0 0.0 3.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CBY23102.1 - 7.5e-06 25.1 0.0 0.002 17.1 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1679) Mlp PF03304.13 CBY23102.1 - 0.18 12.1 0.6 0.34 11.1 0.6 1.5 1 1 0 1 1 1 0 Mlp lipoprotein family TPMT PF05724.11 CBY23103.1 - 5.4e-48 163.5 0.0 6.1e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 CBY23103.1 - 2.3e-05 25.0 0.0 5.1e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY23103.1 - 0.00067 20.3 0.0 0.001 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY23103.1 - 0.00073 19.4 0.0 0.00086 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY23103.1 - 0.0012 18.7 0.1 0.0023 17.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY23103.1 - 0.039 14.7 0.0 0.072 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CBY23103.1 - 0.072 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TSP_1 PF00090.19 CBY23104.1 - 5.3e-10 39.4 13.7 5.3e-10 39.4 13.7 3.1 4 0 0 4 4 4 2 Thrombospondin type 1 domain Dicty_REP PF05086.12 CBY23104.1 - 8.7 4.2 14.8 12 3.8 14.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PDEase_I PF00233.19 CBY23105.1 - 3.8e-50 170.8 0.1 5.3e-50 170.4 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF4194 PF13835.6 CBY23106.1 - 0.063 13.0 0.8 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) Saf_2TM PF18303.1 CBY23107.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain CUB PF00431.20 CBY23110.1 - 8.7e-12 45.4 0.1 4.3e-10 39.9 0.1 2.4 1 1 0 1 1 1 1 CUB domain CUB_2 PF02408.20 CBY23110.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 CUB-like domain Sulfotransfer_3 PF13469.6 CBY23111.1 - 0.0025 18.2 0.0 0.0031 17.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY23111.1 - 0.0059 16.1 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain DUF3727 PF12527.8 CBY23111.1 - 0.025 14.8 0.3 0.034 14.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3727) HNH_5 PF14279.6 CBY23112.1 - 0.015 15.2 0.8 0.041 13.7 0.8 1.8 1 1 0 1 1 1 0 HNH endonuclease Deltaretro_Tax PF05599.11 CBY23112.1 - 0.057 13.9 0.0 0.18 12.4 0.0 1.8 1 1 1 2 2 2 0 Deltaretrovirus Tax protein Kunitz_BPTI PF00014.23 CBY23113.1 - 1.3e-25 89.3 26.8 5.7e-13 48.9 2.6 4.0 3 2 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain Thyroglobulin_1 PF00086.18 CBY23113.1 - 1.3e-08 34.3 1.1 3.2e-08 33.1 1.1 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Trypsin PF00089.26 CBY23114.1 - 1.8e-11 44.3 0.4 3.4e-11 43.4 0.4 1.5 2 0 0 2 2 2 1 Trypsin Kringle PF00051.18 CBY23114.1 - 4.3e-11 43.0 1.6 7.3e-11 42.2 0.5 2.0 2 0 0 2 2 2 1 Kringle domain fn2 PF00040.19 CBY23114.1 - 0.031 14.5 1.8 0.083 13.2 1.8 1.7 1 0 0 1 1 1 0 Fibronectin type II domain Trypsin PF00089.26 CBY23115.1 - 2.5e-34 119.0 0.0 3.1e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin PB1 PF00564.24 CBY23116.1 - 3e-05 23.8 0.0 7.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Ank_2 PF12796.7 CBY23117.1 - 1.6e-75 249.7 6.5 3e-17 63.0 0.0 8.8 5 2 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY23117.1 - 1.5e-70 232.7 6.1 1.1e-10 41.8 0.0 12.1 8 3 6 14 14 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY23117.1 - 3.6e-54 180.1 6.6 2.4e-10 40.4 0.7 9.4 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 CBY23117.1 - 6.6e-49 162.3 13.8 6e-05 23.3 0.0 14.7 15 0 0 15 15 15 7 Ankyrin repeat Ank_3 PF13606.6 CBY23117.1 - 8.3e-45 145.6 3.1 0.0014 18.9 0.0 14.5 15 0 0 15 15 14 9 Ankyrin repeat NACHT PF05729.12 CBY23117.1 - 4.2e-07 30.0 0.1 9e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CBY23117.1 - 0.00024 21.5 0.1 0.00093 19.6 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain DUF3086 PF11285.8 CBY23117.1 - 0.0026 16.9 0.2 0.0052 15.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) AAA_29 PF13555.6 CBY23117.1 - 0.066 13.0 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CBY23117.1 - 0.067 13.5 0.0 0.3 11.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY23117.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AHD PF17793.1 CBY23118.1 - 0.088 12.6 0.2 0.28 11.0 0.2 1.8 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Glyco_hydro_47 PF01532.20 CBY23119.1 - 2.5e-94 316.8 0.0 3.7e-94 316.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 CBY23120.1 - 0.0035 16.3 0.0 0.0042 16.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Guanylate_cyc PF00211.20 CBY23121.1 - 5.9e-49 166.2 0.0 8.7e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 CBY23121.1 - 8.7e-25 87.6 0.1 1.6e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23121.1 - 3.2e-24 85.6 0.1 5.7e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HNOBA PF07701.14 CBY23121.1 - 2.2e-05 24.0 0.4 2.2e-05 24.0 0.4 1.7 2 0 0 2 2 2 1 Heme NO binding associated PID PF00640.23 CBY23122.1 - 5.1e-13 49.2 0.0 3.7e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) PAN_1 PF00024.26 CBY23123.1 - 3.2e-06 27.0 0.7 5.5e-06 26.3 0.7 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 CBY23123.1 - 0.00047 20.0 0.5 0.0012 18.7 0.5 1.7 1 0 0 1 1 1 1 PAN domain Ribosomal_S3Ae PF01015.18 CBY23124.1 - 2.1e-86 288.7 8.1 2.5e-86 288.4 8.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family PemK_toxin PF02452.17 CBY23124.1 - 0.056 13.8 0.6 0.11 12.9 0.6 1.5 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system Pkinase PF00069.25 CBY23125.1 - 1.3e-52 178.8 0.1 1.7e-52 178.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23125.1 - 4.2e-39 134.4 0.0 5.4e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY23125.1 - 1.8e-06 27.0 0.0 3.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY23125.1 - 8.3e-05 22.0 1.5 9e-05 21.9 0.3 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY23125.1 - 0.022 14.1 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 CBY23125.1 - 0.046 12.7 1.9 0.077 12.0 0.3 2.0 3 0 0 3 3 3 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 CBY23125.1 - 0.11 12.0 0.4 0.25 10.8 0.1 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 CBY23125.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L13e PF01294.18 CBY23126.1 - 1.6e-73 246.4 5.4 2.3e-73 245.9 5.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Pkinase PF00069.25 CBY23127.1 - 5.1e-69 232.6 0.0 6.9e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23127.1 - 4e-37 127.9 0.0 5.5e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 CBY23127.1 - 4.9e-07 29.7 0.3 1.3e-06 28.4 0.1 1.8 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.6 CBY23127.1 - 3.4e-06 26.6 0.0 5.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY23127.1 - 0.00041 19.8 0.0 0.00092 18.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY23127.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 CBY23128.1 - 8.7e-12 45.4 13.4 2.1e-06 28.3 1.3 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY23128.1 - 0.0027 18.0 0.1 0.54 10.6 0.1 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain UPF0767 PF15990.5 CBY23129.1 - 0.025 14.7 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 UPF0767 family Keratin_2_head PF16208.5 CBY23129.1 - 0.044 13.9 6.4 0.057 13.6 6.4 1.1 1 0 0 1 1 1 0 Keratin type II head Tic110 PF16940.5 CBY23129.1 - 0.39 9.1 7.2 0.37 9.2 7.2 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Glyco_hydro_47 PF01532.20 CBY23130.1 - 2e-144 481.9 0.2 2.3e-144 481.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 CBY23130.1 - 0.031 13.5 0.1 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) E1-E2_ATPase PF00122.20 CBY23131.1 - 5.7e-54 182.4 0.9 1.7e-53 180.8 0.9 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBY23131.1 - 5.5e-41 140.3 2.1 9.9e-41 139.4 0.1 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CBY23131.1 - 1.8e-25 90.5 0.8 5.6e-25 88.9 0.5 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY23131.1 - 2.1e-19 69.4 0.0 5.4e-18 64.9 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBY23131.1 - 1.1e-18 66.7 0.0 2.4e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBY23131.1 - 0.0079 16.0 0.8 0.038 13.7 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ORC5_C PF14630.6 CBY23132.1 - 2.3e-47 161.9 1.9 3.2e-47 161.4 1.9 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.6 CBY23132.1 - 2.3e-07 31.2 0.0 4.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY23132.1 - 1.2e-05 25.7 0.1 0.00012 22.5 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CBY23132.1 - 0.00015 22.2 0.0 0.00035 21.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CBY23132.1 - 0.0015 18.4 0.0 0.003 17.3 0.0 1.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CBY23132.1 - 0.0027 18.1 0.0 0.0056 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase PIF1 PF05970.14 CBY23132.1 - 0.0072 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase NACHT PF05729.12 CBY23132.1 - 0.017 15.0 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 CBY23132.1 - 0.033 13.8 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 CBY23132.1 - 0.044 13.7 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CBY23132.1 - 0.079 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 CBY23132.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 CBY23132.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 CBY23132.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ORC3_N PF07034.11 CBY23133.1 - 1e-38 133.3 7.9 3.8e-26 92.0 0.3 2.7 2 1 1 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 CBY23133.1 - 1.6e-21 76.8 0.4 2.7e-10 40.5 0.1 2.7 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal RRM_7 PF16367.5 CBY23134.1 - 7.7e-35 118.9 0.6 9.7e-33 112.2 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif CEBP_ZZ PF16366.5 CBY23134.1 - 8.4e-21 74.0 5.3 2.5e-20 72.5 5.5 1.7 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 CBY23134.1 - 1.7e-11 43.8 0.0 1.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.21 CBY23134.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family zf-B_box PF00643.24 CBY23134.1 - 1.9 8.7 6.0 4.2 7.6 6.0 1.5 1 0 0 1 1 1 0 B-box zinc finger AAA_33 PF13671.6 CBY23135.1 - 4.8e-10 39.8 0.0 1e-09 38.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY23135.1 - 5.7e-08 33.4 0.0 9.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 CBY23135.1 - 1.3e-06 28.6 0.0 2.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase 6PF2K PF01591.18 CBY23135.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_17 PF13207.6 CBY23135.1 - 1.2e-05 25.8 0.2 2.3e-05 24.8 0.0 1.6 2 1 0 2 2 1 1 AAA domain KTI12 PF08433.10 CBY23135.1 - 2.6e-05 23.8 1.7 6.3e-05 22.5 0.2 2.2 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_14 PF13173.6 CBY23135.1 - 0.00013 22.0 0.5 0.0005 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CBY23135.1 - 0.00014 22.2 0.1 0.00041 20.8 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY23135.1 - 0.00063 20.0 0.1 0.0018 18.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CBY23135.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 CBY23135.1 - 0.00083 19.4 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CBY23135.1 - 0.001 19.6 0.0 0.0015 19.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 CBY23135.1 - 0.0014 18.6 0.6 0.0078 16.1 0.1 2.3 2 1 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 CBY23135.1 - 0.0018 18.1 0.1 0.0039 17.0 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CBY23135.1 - 0.0024 17.6 0.1 0.0045 16.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBY23135.1 - 0.0028 18.0 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 CBY23135.1 - 0.0029 16.8 0.6 0.0035 16.5 0.1 1.6 2 1 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 CBY23135.1 - 0.0032 17.4 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Rad17 PF03215.15 CBY23135.1 - 0.0063 16.4 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 CBY23135.1 - 0.0073 16.6 0.2 0.023 15.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 CBY23135.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 CBY23135.1 - 0.011 15.8 0.2 0.015 15.4 0.2 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 CBY23135.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 CBY23135.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 CBY23135.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.5 2 0 0 2 2 1 0 Cytidylate kinase AAA_16 PF13191.6 CBY23135.1 - 0.017 15.5 0.1 0.034 14.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CBY23135.1 - 0.021 14.8 0.0 0.021 14.7 0.0 1.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Arf PF00025.21 CBY23135.1 - 0.043 13.3 0.2 0.81 9.1 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family ADK PF00406.22 CBY23135.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Adenylate kinase CoaE PF01121.20 CBY23135.1 - 0.055 13.1 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase RsgA_GTPase PF03193.16 CBY23135.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 CBY23135.1 - 0.097 11.6 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CBY23135.1 - 0.1 12.3 0.1 0.28 10.9 0.0 1.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 CBY23135.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Hydin_ADK PF17213.3 CBY23135.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain AAA_30 PF13604.6 CBY23135.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF974 PF06159.13 CBY23136.1 - 7e-09 35.9 0.0 2.9e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 CBY23136.1 - 0.072 12.5 0.1 1.6 8.0 0.0 2.7 2 1 1 3 3 3 0 TRAPP trafficking subunit Trs65 Gryzun-like PF12742.7 CBY23136.1 - 0.089 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 CBY23136.1 - 0.096 12.4 0.0 0.31 10.7 0.1 2.0 2 1 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 Ras PF00071.22 CBY23138.1 - 7.1e-35 120.0 0.1 8.7e-35 119.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY23138.1 - 1.9e-32 112.0 0.1 2.7e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY23138.1 - 8.1e-09 35.2 0.1 1e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY23138.1 - 1.3e-08 34.5 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY23138.1 - 8.3e-07 29.1 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY23138.1 - 8.5e-05 22.2 0.0 0.0021 17.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBY23138.1 - 0.0026 17.2 0.0 0.0042 16.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 CBY23138.1 - 0.015 14.7 0.0 0.044 13.2 0.0 1.8 2 1 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 CBY23138.1 - 0.034 14.4 0.0 0.083 13.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CBY23138.1 - 0.064 13.2 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 CBY23138.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 CBY23138.1 - 0.08 12.7 0.0 0.22 11.3 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CBY23138.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_S8 PF00082.22 CBY23139.1 - 5.7e-66 222.8 0.0 1.5e-65 221.4 0.0 1.7 1 1 0 1 1 1 1 Subtilase family TPPII PF12580.8 CBY23139.1 - 4.9e-30 104.4 0.1 2.2e-29 102.3 0.0 2.0 2 0 0 2 2 2 1 Tripeptidyl peptidase II GARP PF16731.5 CBY23139.1 - 0.0073 16.0 2.2 0.0073 16.0 2.2 1.8 2 0 0 2 2 2 1 Glutamic acid/alanine-rich protein of Trypanosoma Rap_GAP PF02145.15 CBY23141.1 - 6.3e-19 68.3 0.0 9.8e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Cwf_Cwc_15 PF04889.12 CBY23142.1 - 5.4e-66 222.8 30.4 9.4e-65 218.8 30.4 1.9 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF4119 PF13494.6 CBY23142.1 - 0.022 14.9 3.2 0.022 14.9 3.2 2.0 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF755 PF05501.11 CBY23142.1 - 0.71 10.1 13.6 0.15 12.3 5.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) APG6_N PF17675.1 CBY23142.1 - 5.5 7.5 20.6 11 6.6 20.6 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Taxilin PF09728.9 CBY23143.1 - 0.91 8.6 13.3 0.23 10.6 9.3 1.8 2 0 0 2 2 2 0 Myosin-like coiled-coil protein YabA PF06156.13 CBY23143.1 - 3.3 8.4 11.5 0.13 12.9 3.5 2.6 2 1 1 3 3 3 0 Initiation control protein YabA MutS_V PF00488.21 CBY23144.1 - 1.2e-61 208.1 0.0 2.3e-61 207.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 CBY23144.1 - 6.5e-31 106.9 0.2 1.6e-30 105.6 0.2 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 CBY23144.1 - 2e-29 103.2 0.9 5.1e-28 98.6 0.0 2.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CBY23144.1 - 0.00098 19.4 1.5 0.0029 17.9 0.1 2.5 2 1 0 2 2 2 1 MutS domain II AAA_29 PF13555.6 CBY23144.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain LisH PF08513.11 CBY23145.1 - 0.0084 16.0 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 LisH Troponin-I_N PF11636.8 CBY23145.1 - 0.57 10.2 2.5 1.8 8.6 2.5 1.8 1 0 0 1 1 1 0 Troponin I residues 1-32 YL1 PF05764.13 CBY23146.1 - 0.18 11.9 7.2 0.19 11.8 7.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 CBY23146.1 - 0.38 8.9 6.3 0.37 8.9 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 CBY23146.1 - 0.41 8.7 10.1 0.39 8.8 10.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 CBY23146.1 - 0.44 9.8 6.6 0.51 9.6 6.6 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 CBY23146.1 - 1.4 7.1 5.2 1.4 7.1 5.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 CBY23146.1 - 4.3 5.8 6.3 5.1 5.5 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ras PF00071.22 CBY23147.1 - 7.9e-10 38.6 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY23147.1 - 0.012 15.8 0.0 0.066 13.4 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CBY23147.1 - 0.02 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY23147.1 - 0.029 14.5 0.0 0.16 12.1 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_membrane PF00664.23 CBY23148.1 - 1.4e-35 123.3 6.2 2.2e-35 122.6 6.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBY23148.1 - 2.2e-30 106.0 0.0 5.5e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBY23148.1 - 9.4e-06 25.2 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 CBY23148.1 - 0.00012 21.7 5.9 0.00012 21.7 5.9 2.1 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region DUF87 PF01935.17 CBY23148.1 - 0.058 13.5 1.3 0.12 12.4 0.2 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 CBY23148.1 - 0.2 11.9 0.2 2.7 8.3 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CBY23148.1 - 0.79 10.0 2.7 5.3 7.3 0.5 3.0 3 1 0 3 3 3 0 AAA domain DUF2681 PF10883.8 CBY23148.1 - 6 7.3 5.7 61 4.1 4.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) ATG16 PF08614.11 CBY23149.1 - 0.0056 16.9 18.2 0.0095 16.2 17.5 1.7 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 CBY23149.1 - 0.007 15.7 6.5 0.012 14.9 6.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) 4HB_MCP_1 PF12729.7 CBY23149.1 - 0.01 15.4 10.3 0.015 14.9 10.3 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TMF_TATA_bd PF12325.8 CBY23149.1 - 0.023 14.9 2.4 0.023 14.9 2.4 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 CBY23149.1 - 0.36 8.7 5.8 0.48 8.3 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CHDCT2 PF08074.11 CBY23149.1 - 0.42 10.8 5.1 0.15 12.3 1.2 1.9 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain FliD_N PF02465.18 CBY23149.1 - 0.47 11.2 6.8 1.5 9.6 6.8 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF4349 PF14257.6 CBY23149.1 - 0.65 9.4 7.2 1.2 8.5 7.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) CorA PF01544.18 CBY23149.1 - 0.78 9.0 3.2 1.2 8.4 3.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FlaC_arch PF05377.11 CBY23149.1 - 0.99 9.8 5.4 2 8.9 0.3 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) CHD5 PF04420.14 CBY23149.1 - 1.3 8.9 5.6 2.2 8.1 5.6 1.4 1 0 0 1 1 1 0 CHD5-like protein ADIP PF11559.8 CBY23149.1 - 1.5 8.9 16.5 0.22 11.6 3.1 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 CBY23149.1 - 1.6 8.1 20.8 0.21 10.9 14.8 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 CBY23149.1 - 2.2 8.0 14.4 0.38 10.6 10.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) OmpH PF03938.14 CBY23149.1 - 3.2 8.1 17.7 0.71 10.2 12.4 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CBY23149.1 - 5.2 6.3 13.9 1.3 8.3 10.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 CBY23149.1 - 6.4 6.0 14.1 17 4.6 12.7 1.9 1 1 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 CBY23149.1 - 6.7 5.5 19.5 1.2 7.9 14.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4530 PF15039.6 CBY23149.1 - 7.4 6.8 10.1 4.9 7.3 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) Csm1_N PF18504.1 CBY23149.1 - 7.7 6.9 20.2 4.2 7.8 3.1 3.7 2 1 2 4 4 4 0 Csm1 N-terminal domain Dynein_light PF01221.18 CBY23150.1 - 2.4e-13 50.2 0.0 3.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Rhodanese PF00581.20 CBY23151.1 - 1.3e-06 28.9 0.0 3.5e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Peptidase_C54 PF03416.19 CBY23152.1 - 2.6e-80 269.8 0.0 3.1e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 CBY23152.1 - 0.01 15.4 0.0 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C78 FliG_N PF14842.6 CBY23152.1 - 0.088 13.4 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain SH2 PF00017.24 CBY23153.1 - 2.3e-21 75.7 0.0 4.2e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CBY23153.1 - 4.7e-21 74.1 2.4 6.9e-16 57.6 0.4 2.6 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 CBY23153.1 - 4.9e-18 64.6 0.4 4.6e-09 35.8 0.1 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.6 CBY23153.1 - 1.6e-15 56.7 0.1 3.7e-10 39.5 0.1 2.8 3 0 0 3 3 3 2 Variant SH3 domain hSH3 PF14603.6 CBY23153.1 - 7.3e-05 23.1 0.0 0.00025 21.4 0.0 1.8 2 0 0 2 2 2 1 Helically-extended SH3 domain SH2_2 PF14633.6 CBY23153.1 - 0.0065 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 CBY23153.1 - 0.2 11.9 2.0 0.57 10.5 0.1 2.6 3 0 0 3 3 3 0 Bacterial SH3 domain Fmp27_GFWDK PF10347.9 CBY23154.1 - 2.2e-20 73.4 0.0 1.2e-19 71.0 0.0 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CBY23154.1 - 2.5e-10 40.5 4.0 2.3e-09 37.4 3.9 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF2405) Apt1 PF10351.9 CBY23155.1 - 1.6e-58 198.8 14.0 3.1e-58 197.8 14.0 1.4 1 1 0 1 1 1 1 Golgi-body localisation protein domain RIF5_SNase_2 PF18189.1 CBY23155.1 - 0.034 14.0 0.8 10 5.9 0.4 2.3 2 0 0 2 2 2 0 TbRIF5 SNase domain 2 Trans_reg_C PF00486.28 CBY23155.1 - 0.086 12.9 1.4 0.97 9.6 0.2 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal cwf21 PF08312.12 CBY23155.1 - 0.13 12.4 4.7 0.47 10.6 4.7 2.0 1 0 0 1 1 1 0 cwf21 domain WH1 PF00568.23 CBY23156.1 - 1.1e-21 76.8 0.1 2.1e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.18 CBY23156.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 1 0 1 1 1 0 RanBP1 domain DUF3950 PF13132.6 CBY23156.1 - 0.1 12.3 1.5 1 9.2 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Rer1 PF03248.13 CBY23157.1 - 1.2e-68 230.2 11.3 1.4e-68 230.0 11.3 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 CBY23157.1 - 0.018 14.7 0.3 0.018 14.7 0.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF4639 PF15479.6 CBY23158.1 - 0.0024 16.9 0.4 0.0039 16.2 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4639) Med15 PF09606.10 CBY23160.1 - 1.1e-39 136.8 11.7 1.5e-39 136.4 11.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_2 PF07724.14 CBY23161.1 - 5.5e-44 150.3 0.0 1.1e-43 149.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CBY23161.1 - 1.1e-12 48.5 0.0 2.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBY23161.1 - 2e-08 34.2 0.0 6.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 CBY23161.1 - 2.5e-06 27.3 0.1 3e-05 23.8 0.1 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.23 CBY23161.1 - 2.6e-06 26.7 0.1 4.4e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain IstB_IS21 PF01695.17 CBY23161.1 - 4.4e-05 23.3 0.0 9.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 CBY23161.1 - 4.8e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CBY23161.1 - 5.4e-05 22.4 0.0 9.2e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CBY23161.1 - 5.4e-05 23.5 0.1 0.00019 21.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBY23161.1 - 0.00011 21.6 0.1 0.12 11.8 0.1 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CBY23161.1 - 0.00013 21.5 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CBY23161.1 - 0.00024 21.5 0.0 0.0005 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CBY23161.1 - 0.00044 19.7 0.1 0.0077 15.6 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 CBY23161.1 - 0.00064 18.6 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein TsaE PF02367.17 CBY23161.1 - 0.0007 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBY23161.1 - 0.0016 18.4 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA12 PF10443.9 CBY23161.1 - 0.0098 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein RuvB_N PF05496.12 CBY23161.1 - 0.013 15.2 0.0 0.044 13.5 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBY23161.1 - 0.015 15.9 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBY23161.1 - 0.017 15.5 0.0 0.056 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CBY23161.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 CBY23161.1 - 0.022 15.2 0.2 0.085 13.4 0.1 2.0 2 1 0 2 2 1 0 ABC transporter FdhE PF04216.12 CBY23161.1 - 0.025 14.5 0.1 0.073 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation NACHT PF05729.12 CBY23161.1 - 0.025 14.5 0.0 0.061 13.2 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_33 PF13671.6 CBY23161.1 - 0.028 14.6 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CBY23161.1 - 0.03 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 CBY23161.1 - 0.042 14.0 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_6 PF12774.7 CBY23161.1 - 0.044 12.7 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_3 PF07726.11 CBY23161.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBY23161.1 - 0.045 13.7 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 CBY23161.1 - 0.047 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Microtub_bd PF16796.5 CBY23161.1 - 0.047 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding PhoH PF02562.16 CBY23161.1 - 0.057 12.9 0.1 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 CBY23161.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.7 CBY23161.1 - 0.067 13.2 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain ATP-synt_ab PF00006.25 CBY23161.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 CBY23161.1 - 0.11 12.6 0.2 0.67 10.0 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Bac_DnaA PF00308.18 CBY23161.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.22 CBY23161.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase WIYLD PF10440.9 CBY23161.1 - 0.16 11.8 0.0 0.56 10.1 0.0 1.9 2 0 0 2 2 1 0 Ubiquitin-binding WIYLD domain zf-C2H2_4 PF13894.6 CBY23161.1 - 0.21 12.5 2.1 38 5.5 0.6 2.9 3 0 0 3 3 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY23161.1 - 0.67 10.5 2.5 10 6.7 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Rubredoxin PF00301.20 CBY23161.1 - 8.6 6.5 6.0 17 5.6 0.1 2.7 2 1 0 2 2 2 0 Rubredoxin G-patch PF01585.23 CBY23162.1 - 4.4e-07 29.7 0.0 1.1e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBY23162.1 - 9.1 6.5 7.6 0.54 10.4 0.2 2.7 2 1 0 2 2 2 0 G-patch domain FAT PF02259.23 CBY23163.1 - 2e-27 96.3 11.3 6.3e-27 94.7 11.3 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CBY23163.1 - 1.8e-05 24.7 0.0 0.00011 22.1 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase A_deaminase PF00962.22 CBY23165.1 - 1.3e-111 373.1 0.3 1.4e-110 369.7 0.3 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase ACTL7A_N PF16840.5 CBY23165.1 - 0.15 12.2 0.4 0.78 9.8 0.1 2.3 3 0 0 3 3 3 0 Actin-like protein 7A N-terminus EF-hand_7 PF13499.6 CBY23166.1 - 4.9e-11 42.9 0.2 1.7e-08 34.8 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY23166.1 - 8.3e-09 35.2 0.0 1.1e-06 28.4 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY23166.1 - 9.7e-08 31.0 2.1 0.0015 17.9 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CBY23166.1 - 1.9e-05 23.9 0.9 0.029 13.9 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY23166.1 - 2.1e-05 24.1 1.0 0.14 12.2 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_11 PF08976.11 CBY23166.1 - 0.011 16.6 0.0 0.047 14.6 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY23166.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY23166.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Glyco_hydro_9 PF00759.19 CBY23167.1 - 3.5e-131 438.4 16.5 5.1e-131 437.9 16.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Mucin PF01456.17 CBY23167.1 - 9.4 6.2 54.3 0.93 9.5 35.4 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein SSF PF00474.17 CBY23168.1 - 6.1e-36 124.2 30.9 7.3e-36 123.9 30.9 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family MpPF26 PF07666.11 CBY23168.1 - 5.7 7.1 13.5 0.47 10.6 2.3 3.1 3 0 0 3 3 3 0 M penetrans paralogue family 26 EF-hand_7 PF13499.6 CBY23169.1 - 4.7e-06 27.0 1.3 6e-06 26.6 1.3 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY23169.1 - 6e-06 25.4 1.5 9.1e-05 21.7 1.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBY23169.1 - 2.4e-05 24.1 0.5 0.022 14.6 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY23169.1 - 8.1e-05 22.3 1.5 0.00029 20.5 1.5 1.9 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBY23169.1 - 0.0041 16.6 0.6 0.0041 16.6 0.6 2.0 2 0 0 2 2 2 1 EF hand Caleosin PF05042.13 CBY23169.1 - 0.028 14.4 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Caleosin related protein Nuc_sug_transp PF04142.15 CBY23170.1 - 9.1e-119 396.3 20.1 1.1e-118 396.0 20.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBY23170.1 - 7.4e-08 32.7 33.1 2.5e-05 24.5 8.4 2.3 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 CBY23170.1 - 0.00024 20.8 1.9 0.00024 20.8 1.9 2.4 1 1 0 2 2 2 1 Putative multidrug resistance efflux transporter UAA PF08449.11 CBY23170.1 - 0.00033 20.0 19.3 0.00033 20.0 19.3 2.3 2 1 0 2 2 2 1 UAA transporter family PUNUT PF16913.5 CBY23170.1 - 0.0029 16.9 26.0 0.0037 16.5 24.4 1.8 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 CBY23170.1 - 0.0082 15.5 17.8 0.087 12.2 17.6 2.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nairovirus_M PF07948.11 CBY23170.1 - 0.089 11.0 0.2 0.12 10.6 0.2 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DUF202 PF02656.15 CBY23170.1 - 0.12 12.8 0.1 0.12 12.8 0.1 3.4 3 1 0 3 3 2 0 Domain of unknown function (DUF202) TMEM234 PF10639.9 CBY23170.1 - 0.33 11.0 11.9 0.2 11.7 1.5 2.6 2 1 0 2 2 2 0 Putative transmembrane family 234 DMT_6 PF04342.12 CBY23170.1 - 0.4 10.9 12.7 1.1 9.5 3.0 3.1 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) ATPase_gene1 PF09527.10 CBY23170.1 - 7.1 6.9 10.4 12 6.2 0.3 3.7 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter JTB PF05439.12 CBY23171.1 - 8.9e-14 51.5 8.4 1.6e-13 50.7 7.2 2.1 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) Adap_comp_sub PF00928.21 CBY23171.1 - 0.022 14.1 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Adaptor complexes medium subunit family eIF-5_eIF-2B PF01873.17 CBY23175.1 - 2.6e-33 114.4 0.2 4.3e-33 113.7 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Myticin-prepro PF10690.9 CBY23175.1 - 0.22 11.8 2.3 0.51 10.6 2.3 1.6 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel RecR PF02132.15 CBY23175.1 - 0.28 10.8 1.7 0.49 10.0 1.7 1.4 1 0 0 1 1 1 0 RecR protein zinc_ribbon_6 PF14599.6 CBY23175.1 - 0.55 10.3 3.7 2.6 8.1 1.8 2.3 2 0 0 2 2 2 0 Zinc-ribbon MORN PF02493.20 CBY23176.1 - 3.4e-26 89.5 36.4 4.2e-05 23.2 2.3 7.1 7 0 0 7 7 7 6 MORN repeat DUF1053 PF06327.14 CBY23176.1 - 0.016 15.7 2.7 0.03 14.9 2.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) BNIP3 PF06553.12 CBY23176.1 - 0.28 10.9 2.2 0.39 10.4 2.2 1.2 1 0 0 1 1 1 0 BNIP3 Virul_Fac PF10139.9 CBY23176.1 - 0.38 8.9 0.8 0.6 8.3 0.8 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor MORN PF02493.20 CBY23177.1 - 6.3e-11 41.5 18.5 6.2e-05 22.7 2.9 3.5 3 0 0 3 3 3 3 MORN repeat Ank_2 PF12796.7 CBY23178.1 - 8.1e-14 52.0 2.8 2.6e-09 37.5 0.2 4.3 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY23178.1 - 7.4e-12 45.5 2.9 5.6e-10 39.6 0.2 4.3 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY23178.1 - 1.2e-09 38.2 0.2 5.1e-07 29.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY23178.1 - 4.3e-09 36.4 0.6 0.0009 19.6 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CBY23178.1 - 5.9e-08 32.4 2.2 0.039 14.5 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Sigma70_r2 PF04542.14 CBY23178.1 - 0.1 12.4 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-70 region 2 AT_hook PF02178.19 CBY23179.1 - 0.021 14.6 4.6 0.021 14.6 4.6 3.3 3 0 0 3 3 3 0 AT hook motif ShK PF01549.24 CBY23181.1 - 2.8e-05 24.6 2.9 0.0001 22.8 2.9 2.0 1 0 0 1 1 1 1 ShK domain-like Kelch_1 PF01344.25 CBY23181.1 - 6e-05 22.5 1.2 0.28 10.8 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY23181.1 - 0.0051 16.7 0.1 1.8 8.7 0.1 2.8 2 0 0 2 2 2 2 Kelch motif DUF116 PF01976.17 CBY23181.1 - 0.046 13.2 1.4 0.099 12.2 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF116 Kelch_6 PF13964.6 CBY23181.1 - 0.76 10.2 3.3 1.6 9.1 0.1 3.0 2 1 1 3 3 3 0 Kelch motif Tropomyosin_1 PF12718.7 CBY23182.1 - 0.087 13.0 18.6 0.22 11.7 0.7 3.7 3 1 0 3 3 3 0 Tropomyosin like SlyX PF04102.12 CBY23182.1 - 2 9.1 24.0 0.45 11.2 2.1 4.9 3 2 2 5 5 5 0 SlyX Cation_ATPase PF13246.6 CBY23182.1 - 2.4 8.3 4.4 6.2 7.0 0.2 3.1 2 1 1 3 3 3 0 Cation transport ATPase (P-type) Mt_ATP-synt_D PF05873.12 CBY23182.1 - 8.9 6.1 7.6 21 5.0 0.0 3.6 4 1 1 5 5 5 0 ATP synthase D chain, mitochondrial (ATP5H) Pkinase PF00069.25 CBY23183.1 - 5.8e-68 229.1 0.0 1.4e-67 227.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23183.1 - 8.4e-39 133.4 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CBY23183.1 - 1.1e-29 102.0 28.3 9e-16 57.5 7.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 CBY23183.1 - 6e-09 36.1 0.1 1.4e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 CBY23183.1 - 4.4e-07 30.5 3.4 9.6e-07 29.4 3.4 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CBY23183.1 - 0.0018 17.3 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY23183.1 - 0.0043 16.4 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY23183.1 - 0.03 13.7 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prim_Zn_Ribbon PF08273.12 CBY23183.1 - 0.055 13.7 2.4 0.84 10.0 0.1 2.8 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase C1_2 PF03107.16 CBY23183.1 - 0.1 12.9 17.6 0.57 10.5 3.1 2.6 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.5 CBY23183.1 - 1.4 9.1 15.2 0.14 12.3 5.0 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 CBY23183.1 - 8.8 6.3 25.0 11 6.0 11.0 2.5 2 0 0 2 2 2 0 PHD-finger TaqI_C PF12950.7 CBY23184.1 - 0.14 12.2 0.2 0.29 11.2 0.2 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain ELP6 PF09807.9 CBY23186.1 - 0.024 14.1 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Elongation complex protein 6 RPAP3_C PF13877.6 CBY23187.1 - 0.11 13.1 1.1 0.24 12.0 0.0 2.1 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 ATP-synt_ab PF00006.25 CBY23188.1 - 8.4e-62 208.6 0.0 1.7e-61 207.6 0.0 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBY23188.1 - 4.7e-22 78.3 1.9 1e-21 77.2 1.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 CBY23188.1 - 0.0033 17.3 0.1 0.0088 16.0 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase RnfC_N PF13375.6 CBY23188.1 - 0.011 15.7 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPase PF06745.13 CBY23188.1 - 0.029 13.7 1.6 0.091 12.1 0.7 2.0 2 0 0 2 2 2 0 KaiC T3SS_ATPase_C PF18269.1 CBY23188.1 - 0.029 14.2 0.2 0.27 11.1 0.2 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 CBY23188.1 - 0.071 13.4 0.2 0.29 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBY23188.1 - 0.09 11.9 0.5 0.29 10.3 0.2 1.8 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 CBY23188.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SpecificRecomb PF10136.9 CBY23189.1 - 2.7 6.2 23.7 0.14 10.5 14.4 2.1 1 1 1 2 2 2 0 Site-specific recombinase Radical_SAM_C PF16199.5 CBY23190.1 - 1.7e-32 111.3 0.1 1.1e-31 108.7 0.1 2.2 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CBY23190.1 - 2.7e-19 70.2 1.4 1.2e-17 64.8 0.1 3.0 4 0 0 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CBY23190.1 - 8.7e-08 32.4 0.1 1.6e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY23190.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY23190.1 - 0.013 15.9 0.2 0.028 14.8 0.2 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Linker_histone PF00538.19 CBY23190.1 - 0.085 13.2 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family FR47 PF08445.10 CBY23190.1 - 0.091 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SMC_Nse1 PF07574.13 CBY23191.1 - 0.00091 19.2 0.1 0.074 12.9 0.0 2.4 2 1 0 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CBY23191.1 - 0.035 14.4 11.2 0.088 13.1 11.2 1.8 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.22 CBY23191.1 - 3.1 7.7 10.6 6.8 6.7 10.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CCG PF02754.16 CBY23192.1 - 0.052 13.8 0.1 0.89 9.8 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich domain Epimerase PF01370.21 CBY23193.1 - 5.9e-23 81.6 0.0 7.3e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBY23193.1 - 2.7e-17 63.2 0.0 4.4e-17 62.5 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CBY23193.1 - 1.1e-08 34.6 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CBY23193.1 - 5.8e-08 32.2 0.0 3.1e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 CBY23193.1 - 7.2e-08 31.8 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CBY23193.1 - 1.2e-05 24.7 0.0 4.4e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CBY23193.1 - 0.089 12.7 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 KR domain zf-RING_2 PF13639.6 CBY23195.1 - 2.3e-09 37.4 5.5 4.9e-09 36.4 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY23195.1 - 1.9e-07 30.8 5.7 4.3e-07 29.7 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY23195.1 - 8.1e-07 28.8 6.0 2.2e-06 27.4 6.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY23195.1 - 2.9e-06 27.0 3.2 5.6e-06 26.1 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY23195.1 - 1.8e-05 24.6 8.1 3.7e-05 23.6 8.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBY23195.1 - 3e-05 24.2 5.3 0.00012 22.3 5.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBY23195.1 - 0.00089 19.2 6.9 0.0022 18.0 6.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CBY23195.1 - 0.0054 16.4 3.3 0.013 15.2 3.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBY23195.1 - 0.077 13.2 4.1 0.23 11.6 4.1 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CBY23195.1 - 0.2 11.5 5.7 0.5 10.2 5.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_16 PF17034.5 CBY23195.1 - 0.34 11.1 5.8 4.5 7.5 0.5 2.8 2 0 0 2 2 2 0 Zinc-ribbon like family zf-Nse PF11789.8 CBY23195.1 - 0.45 10.4 2.8 1.2 9.0 2.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LSM PF01423.22 CBY23197.1 - 1.3e-16 60.0 1.7 1.6e-16 59.7 1.7 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CBY23197.1 - 0.002 17.7 0.3 0.0029 17.2 0.3 1.4 1 0 0 1 1 1 1 Hfq protein Methyltransf_25 PF13649.6 CBY23198.1 - 3.2e-21 75.8 0.3 1.3e-12 48.2 0.1 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CBY23198.1 - 7.4e-21 74.5 0.4 1e-14 54.6 0.2 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CBY23198.1 - 2.6e-18 66.4 0.1 1.9e-12 47.7 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CBY23198.1 - 2.4e-11 44.3 0.1 4.1e-05 24.3 0.1 2.6 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 CBY23198.1 - 7.3e-10 38.7 0.1 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Spermine_synth PF01564.17 CBY23198.1 - 2.7e-09 36.7 2.9 3.2e-07 29.9 0.1 2.4 2 0 0 2 2 2 2 Spermine/spermidine synthase domain RrnaAD PF00398.20 CBY23198.1 - 1.8e-08 33.8 0.1 1.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 CBY23198.1 - 2.9e-05 23.5 1.1 7.3e-05 22.2 0.4 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 CBY23198.1 - 0.00014 21.8 0.6 0.054 13.4 0.1 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBY23198.1 - 0.0011 19.0 0.4 0.053 13.5 0.1 2.8 3 0 0 3 3 3 1 Methyltransferase domain TPMT PF05724.11 CBY23198.1 - 0.0015 18.2 0.0 0.0034 17.1 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 CBY23198.1 - 0.02 14.5 3.9 0.075 12.6 0.4 2.3 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 CBY23198.1 - 0.024 14.3 0.1 0.18 11.4 0.1 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Response_reg PF00072.24 CBY23198.1 - 0.12 12.5 0.6 0.59 10.3 0.2 2.3 2 0 0 2 2 2 0 Response regulator receiver domain OCRE PF17780.1 CBY23199.1 - 0.35 10.9 13.6 0.86 9.7 13.3 1.9 1 1 0 1 1 1 0 OCRE domain Pkinase PF00069.25 CBY23200.1 - 2.8e-62 210.5 0.0 3.2e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23200.1 - 8.2e-27 94.1 0.0 9.7e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY23200.1 - 3.1e-05 23.4 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY23200.1 - 5e-05 22.8 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY23200.1 - 0.0083 14.9 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBY23200.1 - 0.034 13.7 0.0 0.081 12.4 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Aldose_epim PF01263.20 CBY23201.1 - 5.7e-20 71.8 0.4 6.3e-20 71.7 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase VRR_NUC PF08774.11 CBY23201.1 - 0.032 14.3 0.1 0.083 13.0 0.0 1.7 2 1 0 2 2 2 0 VRR-NUC domain Peptidase_C97 PF05903.14 CBY23202.1 - 1.5e-05 24.8 0.1 1.9e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 CBY23202.1 - 0.0016 18.1 0.1 0.0018 17.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4796) LRAT PF04970.13 CBY23202.1 - 0.051 13.9 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Pkinase PF00069.25 CBY23204.1 - 5.8e-69 232.4 1.1 8.4e-63 212.2 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain cNMP_binding PF00027.29 CBY23204.1 - 4.4e-44 148.5 0.4 6.4e-22 77.4 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY23204.1 - 1.2e-29 103.4 0.3 9.2e-28 97.2 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY23204.1 - 0.00063 19.1 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY23204.1 - 0.0013 17.6 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Ras_bdg_2 PF14847.6 CBY23204.1 - 0.19 12.1 1.9 0.28 11.5 0.2 2.2 2 0 0 2 2 2 0 Ras-binding domain of Byr2 NDK PF00334.19 CBY23205.1 - 1.3e-52 177.4 0.0 1.5e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase EF1_GNE PF00736.19 CBY23206.1 - 4.1e-33 113.4 2.4 8.6e-33 112.4 2.4 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CBY23206.1 - 4.7e-10 39.7 5.6 4.7e-10 39.7 5.6 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.12 CBY23206.1 - 0.0025 17.6 4.1 0.0035 17.1 4.1 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 CBY23206.1 - 0.014 15.5 2.7 0.019 15.1 2.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein eIF3_subunit PF08597.10 CBY23206.1 - 0.037 13.9 7.9 0.052 13.5 7.9 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Q_salvage PF10343.9 CBY23207.1 - 0.0035 17.0 0.0 0.0042 16.7 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family PAS_8 PF13188.7 CBY23207.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 PAS domain Q_salvage PF10343.9 CBY23208.1 - 2.3e-30 106.2 0.1 2.6e-30 106.0 0.1 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Vpu PF00558.19 CBY23209.1 - 1.7 8.5 5.1 0.55 10.0 0.9 2.0 2 0 0 2 2 2 0 Vpu protein Mucin PF01456.17 CBY23210.1 - 0.046 13.7 22.3 0.12 12.3 22.3 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 CBY23210.1 - 1.9 6.5 6.4 2.8 6.0 6.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AAA_6 PF12774.7 CBY23211.1 - 3e-162 539.1 0.0 6.5e-162 538.1 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBY23211.1 - 3.8e-138 460.9 9.4 3.8e-138 460.9 9.4 2.7 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBY23211.1 - 1.6e-109 365.8 0.2 1.6e-109 365.8 0.2 2.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBY23211.1 - 3.5e-100 334.6 0.0 1e-99 333.1 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBY23211.1 - 6.8e-65 218.3 0.3 6.8e-65 218.3 0.3 3.4 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBY23211.1 - 1.4e-49 168.0 2.0 1.9e-46 157.9 0.1 4.0 3 1 1 4 4 4 1 P-loop containing dynein motor region Dynein_heavy PF03028.15 CBY23211.1 - 3.4e-48 162.7 0.0 2.7e-45 153.3 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBY23211.1 - 3.2e-45 154.7 10.7 7.1e-45 153.5 10.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CBY23211.1 - 3.6e-38 130.9 0.0 1.5e-32 112.7 0.0 2.7 1 1 1 2 2 2 2 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 CBY23211.1 - 1.1e-20 74.0 0.4 5.9e-20 71.7 0.2 2.5 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBY23211.1 - 1.5e-20 73.2 0.1 1.9e-19 69.7 0.0 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CBY23211.1 - 6.5e-07 29.4 0.0 0.1 12.6 0.0 6.2 6 1 0 6 6 5 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBY23211.1 - 0.022 15.3 0.0 0.45 11.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 CBY23211.1 - 0.023 13.3 0.2 1.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF2018 PF09442.10 CBY23211.1 - 0.06 14.3 5.4 18 6.4 0.0 4.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) AAA_16 PF13191.6 CBY23211.1 - 0.082 13.3 0.0 9.5 6.6 0.0 3.1 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 CBY23211.1 - 0.1 13.0 0.2 2.8 8.4 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Exonuc_VII_L PF02601.15 CBY23211.1 - 3.6 7.1 15.6 0.17 11.4 0.2 3.5 3 0 0 3 3 3 0 Exonuclease VII, large subunit Pro-rich_19 PF15455.6 CBY23212.1 - 0.019 14.1 0.2 0.019 14.1 0.2 1.6 2 0 0 2 2 2 0 Proline-rich 19 DUF682 PF05081.12 CBY23212.1 - 0.033 13.9 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF682) Transposase_22 PF02994.14 CBY23212.1 - 0.057 13.6 0.4 9.8 6.4 0.1 2.6 2 0 0 2 2 2 0 L1 transposable element RBD-like domain Ephrin PF00812.17 CBY23213.1 - 4.6e-11 42.9 0.0 8.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Ephrin Sod_Cu PF00080.20 CBY23214.1 - 2.2e-62 209.4 13.6 4.4e-31 108.0 3.0 2.0 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) DNA_Packaging_2 PF11123.8 CBY23214.1 - 0.02 15.1 2.3 4.4 7.6 0.2 3.0 3 0 0 3 3 3 0 DNA packaging protein Apis_Csd PF11671.8 CBY23215.1 - 0.04 13.9 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Lectin_C PF00059.21 CBY23215.1 - 0.053 14.3 0.1 0.13 13.0 0.0 1.7 2 0 0 2 2 2 0 Lectin C-type domain Pox_E10 PF04805.12 CBY23215.1 - 0.061 13.2 1.6 0.11 12.4 1.6 1.4 1 0 0 1 1 1 0 E10-like protein conserved region Thyroglobulin_1 PF00086.18 CBY23216.1 - 2.1e-10 40.1 3.3 1.5e-07 31.0 0.9 2.7 2 1 0 2 2 2 2 Thyroglobulin type-1 repeat Galactosyl_T PF01762.21 CBY23217.1 - 5.1e-38 130.8 0.1 1.1e-37 129.8 0.0 1.5 2 0 0 2 2 2 1 Galactosyltransferase EF-hand_1 PF00036.32 CBY23218.1 - 4e-10 38.5 4.2 0.00018 20.8 0.5 3.4 2 1 1 3 3 3 2 EF hand EF-hand_7 PF13499.6 CBY23218.1 - 7.9e-09 35.8 2.5 7.9e-09 35.8 2.5 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY23218.1 - 1.7e-08 34.2 1.3 1.5e-07 31.2 1.0 3.3 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY23218.1 - 6.9e-08 31.6 0.8 0.0017 17.8 0.4 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY23218.1 - 2.6e-07 30.0 6.1 0.0014 18.4 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain Dockerin_1 PF00404.18 CBY23218.1 - 0.005 17.0 4.2 0.046 13.9 0.1 2.9 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_4 PF12763.7 CBY23218.1 - 0.056 13.4 0.6 0.082 12.9 0.6 1.4 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Glycos_transf_2 PF00535.26 CBY23220.1 - 3.9e-24 85.4 0.0 7e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CBY23220.1 - 5.8e-08 32.3 0.1 1.6e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY23220.1 - 1.5e-06 27.9 0.0 4.8e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 CBY23220.1 - 4.8e-06 26.6 0.0 7.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3236 PF11576.8 CBY23220.1 - 0.2 11.3 0.0 22 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) Sod_Cu PF00080.20 CBY23222.1 - 8.1e-23 81.2 2.6 1.3e-22 80.5 2.6 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Trypan_PARP PF05887.11 CBY23224.1 - 1.3e-06 28.4 4.2 2.5e-06 27.5 4.2 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 CBY23224.1 - 0.15 11.6 5.8 0.22 11.1 5.8 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) PsbH PF00737.20 CBY23224.1 - 0.33 10.7 1.3 0.77 9.5 0.9 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein ER_lumen_recept PF00810.18 CBY23225.1 - 2.7e-51 174.3 9.3 4.7e-51 173.5 9.3 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CBY23225.1 - 0.22 11.3 13.2 0.81 9.5 0.6 3.7 2 1 2 4 4 4 0 PQ loop repeat Rotamase PF00639.21 CBY23226.1 - 8.8e-13 49.0 0.0 1.2e-12 48.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CBY23226.1 - 1.9e-09 38.0 0.0 2.4e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CBY23226.1 - 0.063 14.1 0.0 0.092 13.6 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain HMG_box PF00505.19 CBY23227.1 - 8.3e-24 83.8 4.0 8.3e-24 83.8 4.0 2.5 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY23227.1 - 6.9e-09 36.2 2.1 6.9e-09 36.2 2.1 2.6 3 0 0 3 3 3 1 HMG-box domain S4 PF01479.25 CBY23227.1 - 0.076 12.7 1.9 5.2 6.9 0.1 2.5 2 0 0 2 2 2 0 S4 domain VWA PF00092.28 CBY23228.1 - 0.0023 18.2 0.0 0.0074 16.5 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY23228.1 - 0.012 16.3 0.1 0.58 10.8 0.1 2.4 1 1 0 1 1 1 0 von Willebrand factor type A domain TFIIB PF00382.19 CBY23228.1 - 0.15 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Pkinase PF00069.25 CBY23229.1 - 1.1e-63 215.1 0.0 1.3e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23229.1 - 2.9e-44 151.3 0.0 3.6e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY23229.1 - 5.2e-05 22.7 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY23229.1 - 0.00055 19.0 0.2 0.00076 18.5 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CBY23229.1 - 0.0032 17.1 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CBY23229.1 - 0.0043 16.7 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBY23229.1 - 0.033 13.6 0.1 0.053 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY23229.1 - 0.074 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBY23229.1 - 0.18 11.3 1.4 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL MIOX PF05153.15 CBY23230.1 - 6.5e-107 356.7 5.0 7.6e-107 356.5 5.0 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 CBY23230.1 - 0.14 12.4 0.1 0.39 10.9 0.1 1.7 2 0 0 2 2 2 0 HD domain Filament PF00038.21 CBY23232.1 - 1.1e-08 35.1 42.8 1.1e-08 35.1 42.8 3.5 2 1 1 3 3 3 1 Intermediate filament protein DUF1664 PF07889.12 CBY23232.1 - 6.3e-06 26.2 8.5 6.3e-06 26.2 8.5 5.8 4 2 2 6 6 6 3 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBY23232.1 - 5.1e-05 22.3 17.2 5.1e-05 22.3 17.2 4.4 2 1 1 4 4 4 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CBY23232.1 - 0.00013 22.0 18.3 0.00013 22.0 18.3 5.0 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 CBY23232.1 - 0.00024 19.9 32.1 0.00024 19.9 32.1 3.6 2 1 2 4 4 4 1 AAA domain Fib_alpha PF08702.10 CBY23232.1 - 0.00029 21.0 56.3 0.073 13.3 5.6 4.6 3 1 1 4 4 4 3 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 CBY23232.1 - 0.00046 19.6 15.2 0.00046 19.6 15.2 4.5 2 1 1 4 4 4 1 Protein of unknown function (DUF3450) HAP1_N PF04849.13 CBY23232.1 - 0.00074 18.8 24.0 0.00074 18.8 24.0 4.2 2 1 2 4 4 4 2 HAP1 N-terminal conserved region TRAF_BIRC3_bd PF16673.5 CBY23232.1 - 0.0013 18.5 3.4 0.0013 18.5 3.4 4.5 5 0 0 5 5 3 1 TNF receptor-associated factor BIRC3 binding domain MIP-T3_C PF17749.1 CBY23232.1 - 0.0014 18.6 11.1 0.0014 18.6 11.1 4.9 3 1 2 5 5 3 1 Microtubule-binding protein MIP-T3 C-terminal region Tropomyosin_1 PF12718.7 CBY23232.1 - 0.0025 18.0 12.0 0.0025 18.0 12.0 5.4 2 1 3 5 5 5 2 Tropomyosin like ERM PF00769.19 CBY23232.1 - 0.0054 16.6 25.2 0.0054 16.6 25.2 4.7 2 1 1 4 4 4 1 Ezrin/radixin/moesin family MscS_porin PF12795.7 CBY23232.1 - 0.0059 16.2 15.7 0.0059 16.2 15.7 4.5 3 1 1 4 4 4 1 Mechanosensitive ion channel porin domain HMMR_N PF15905.5 CBY23232.1 - 0.0071 15.9 35.3 0.0071 15.9 35.3 4.5 2 1 2 4 4 4 1 Hyaluronan mediated motility receptor N-terminal Seryl_tRNA_N PF02403.22 CBY23232.1 - 0.033 14.4 70.6 0.17 12.1 17.7 5.7 2 1 4 6 6 6 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 CBY23232.1 - 0.076 13.4 42.1 0.13 12.7 3.4 8.1 5 2 2 7 7 7 0 Flagella accessory protein C (FlaC) AphA_like PF14557.6 CBY23232.1 - 0.18 11.5 8.1 0.17 11.6 5.5 2.2 1 1 0 2 2 2 0 Putative AphA-like transcriptional regulator DUF4407 PF14362.6 CBY23232.1 - 0.2 10.9 59.7 0.032 13.6 14.6 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 CBY23232.1 - 0.25 11.4 80.3 0.02 14.9 14.2 6.3 3 1 3 6 6 6 0 Designed helical repeat protein 10 domain SHE3 PF17078.5 CBY23232.1 - 0.45 10.2 54.6 0.53 10.0 16.9 4.5 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Fez1 PF06818.15 CBY23232.1 - 0.46 10.9 62.2 3.4 8.1 26.7 4.2 2 1 1 3 3 3 0 Fez1 Baculo_PEP_C PF04513.12 CBY23232.1 - 0.56 10.2 42.9 0.058 13.4 7.9 5.4 2 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 CBY23232.1 - 1.1 9.1 58.6 0.095 12.5 11.5 5.0 2 1 1 4 4 4 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 CBY23232.1 - 1.6 8.8 63.2 0.028 14.5 15.5 4.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 CBY23232.1 - 1.9 7.9 59.8 0.65 9.5 22.9 4.0 2 1 1 3 3 3 0 Leucine zipper DUF3287 PF11690.8 CBY23232.1 - 3.1 7.5 7.0 8.8 6.1 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) YabA PF06156.13 CBY23232.1 - 4.1 8.1 45.9 1.7 9.3 6.7 6.2 3 1 3 6 6 6 0 Initiation control protein YabA DUF5082 PF16888.5 CBY23232.1 - 4.4 7.6 51.5 0.26 11.6 11.8 5.3 2 2 3 5 5 5 0 Domain of unknown function (DUF5082) DUF4472 PF14739.6 CBY23232.1 - 7.2 7.4 54.7 0.5 11.1 14.1 5.7 4 2 0 4 4 4 0 Domain of unknown function (DUF4472) TACC_C PF05010.14 CBY23232.1 - 7.7 6.2 63.9 0.5 10.1 28.9 3.8 2 1 3 5 5 5 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Matrilin_ccoil PF10393.9 CBY23232.1 - 8 6.4 19.9 0.036 13.9 1.7 4.3 5 0 0 5 5 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Iso_dh PF00180.20 CBY23234.1 - 0.053 12.6 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase SSXT PF05030.12 CBY23234.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Peptidase_M24_C PF16188.5 CBY23234.1 - 0.14 12.3 0.0 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 DUF1358 PF07096.11 CBY23235.1 - 0.0027 17.7 0.5 0.0052 16.8 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1358) DUF1275 PF06912.11 CBY23235.1 - 0.016 15.1 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Ribosomal_L36e PF01158.18 CBY23236.1 - 1.2e-40 137.7 6.2 1.3e-40 137.5 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Mob1_phocein PF03637.17 CBY23237.1 - 1.9e-60 203.7 0.3 2.3e-60 203.5 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family TPR_19 PF14559.6 CBY23239.1 - 2.4e-31 108.1 33.5 1.1e-07 32.2 2.3 12.7 11 2 1 12 12 12 8 Tetratricopeptide repeat TPR_16 PF13432.6 CBY23239.1 - 3.5e-19 69.2 24.7 0.0033 18.0 0.0 9.6 5 2 7 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.6 CBY23239.1 - 2.7e-17 62.0 34.6 0.099 13.5 0.0 14.5 10 3 7 17 17 14 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBY23239.1 - 1.3e-13 49.9 37.9 0.45 10.8 0.1 15.5 19 0 0 19 19 17 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBY23239.1 - 5.4e-11 42.6 29.4 0.011 16.0 0.1 10.8 8 4 2 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBY23239.1 - 7.8e-10 38.2 24.6 0.47 10.8 0.0 11.7 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_21 PF09976.9 CBY23239.1 - 1.6e-09 37.8 32.1 0.0017 18.1 2.2 6.9 4 2 2 6 6 6 4 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 CBY23239.1 - 1.9e-09 36.9 9.5 2.8 8.2 0.0 9.8 11 0 0 11 11 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY23239.1 - 3e-09 37.0 17.5 0.0013 18.9 0.1 7.1 6 2 0 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBY23239.1 - 3.8e-09 36.0 13.2 1 9.3 0.1 10.8 12 0 0 12 12 11 1 Tetratricopeptide repeat PknG_TPR PF16918.5 CBY23239.1 - 1e-07 31.0 5.5 0.0017 17.2 0.8 3.2 3 0 0 3 3 3 2 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 CBY23239.1 - 1.1e-07 32.0 26.6 4.9 8.0 0.2 12.8 15 0 0 15 15 12 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY23239.1 - 1.9e-07 30.6 6.2 0.013 15.1 0.0 7.9 9 1 1 10 10 10 1 TPR repeat TPR_5 PF12688.7 CBY23239.1 - 0.00013 22.2 12.0 0.01 16.1 1.9 4.2 3 1 0 3 3 3 2 Tetratrico peptide repeat YfiO PF13525.6 CBY23239.1 - 0.00043 20.1 2.3 0.17 11.6 0.2 4.0 3 0 0 3 3 3 1 Outer membrane lipoprotein SNAP PF14938.6 CBY23239.1 - 0.0024 17.4 22.9 0.047 13.1 1.7 4.2 3 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 CBY23239.1 - 0.026 15.1 10.5 53 4.9 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.20 CBY23239.1 - 0.13 12.6 0.3 9.9 6.7 0.2 4.5 6 0 0 6 6 4 0 PPR repeat RPN7 PF10602.9 CBY23239.1 - 0.54 10.0 12.4 8 6.1 0.1 5.8 4 1 3 7 7 7 0 26S proteasome subunit RPN7 FYVE_2 PF02318.16 CBY23240.1 - 0.024 14.8 0.4 0.061 13.5 0.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Amino_oxidase PF01593.24 CBY23241.1 - 1.8e-13 50.6 0.5 3.6e-12 46.3 0.0 2.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CBY23241.1 - 1.2e-10 41.5 1.0 4.3e-10 39.7 0.2 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CBY23241.1 - 5.4e-09 36.1 4.2 5.6e-08 32.7 2.3 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CBY23241.1 - 1e-07 31.7 0.0 5.8e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CBY23241.1 - 1.3e-06 27.9 0.0 2.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 CBY23241.1 - 1.3e-06 27.7 7.0 9.3e-06 25.0 2.4 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 CBY23241.1 - 2.1e-06 27.2 0.0 7.1e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBY23241.1 - 9.9e-06 24.5 1.8 0.00058 18.7 0.8 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 CBY23241.1 - 5.1e-05 23.7 0.7 0.0027 18.2 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY23241.1 - 5.7e-05 22.5 0.1 9.7e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CBY23241.1 - 0.0035 16.5 1.3 0.007 15.5 1.3 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A GDI PF00996.18 CBY23241.1 - 0.014 13.9 0.1 0.05 12.1 0.0 1.9 3 0 0 3 3 3 0 GDP dissociation inhibitor Shikimate_DH PF01488.20 CBY23241.1 - 0.02 15.0 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 CBY23241.1 - 0.054 12.3 0.1 0.09 11.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 CBY23241.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Tom22 PF04281.13 CBY23241.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TrkA_N PF02254.18 CBY23241.1 - 0.1 12.8 0.1 0.6 10.4 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain YjeF_N PF03853.15 CBY23241.1 - 0.12 12.2 0.4 11 5.9 0.1 2.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus UDPG_MGDP_dh_N PF03721.14 CBY23241.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIT_CC PF16559.5 CBY23242.1 - 0.39 10.6 10.2 0.82 9.6 4.8 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 CBY23243.1 - 0.0033 18.0 0.8 0.0033 18.0 0.8 2.1 2 0 0 2 2 2 1 Initiation control protein YabA MAP7 PF05672.11 CBY23243.1 - 0.031 14.0 23.8 0.042 13.5 23.8 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Peptidase_C10 PF01640.17 CBY23243.1 - 0.25 11.6 4.8 0.3 11.4 4.8 1.1 1 0 0 1 1 1 0 Peptidase C10 family K_trans PF02705.16 CBY23243.1 - 0.95 7.9 3.3 1.1 7.7 3.3 1.1 1 0 0 1 1 1 0 K+ potassium transporter CDK5_activator PF03261.15 CBY23243.1 - 2.5 7.5 11.6 3.3 7.2 11.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein NRBF2 PF08961.10 CBY23243.1 - 2.7 7.5 15.1 13 5.3 15.0 1.8 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Arc_PepC_II PF06847.11 CBY23243.1 - 4.8 7.8 6.7 2.3 8.8 0.3 2.3 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II DUF3504 PF12012.8 CBY23244.1 - 7.1e-28 97.6 0.1 7.1e-28 97.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) TFIIA PF03153.13 CBY23244.1 - 0.29 11.1 20.0 0.42 10.6 20.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CBY23244.1 - 3.4 6.2 8.7 4.6 5.8 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TRAF6_Z2 PF18048.1 CBY23245.1 - 4.1 7.6 5.8 1 9.5 0.6 2.8 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Zn_Tnp_IS91 PF14319.6 CBY23245.1 - 8.7 6.5 13.2 6.5 6.9 3.5 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain Tmemb_cc2 PF10267.9 CBY23247.1 - 3.2e-08 33.1 18.5 3.2e-08 33.1 18.5 2.4 1 1 1 2 2 2 2 Predicted transmembrane and coiled-coil 2 protein Cep57_MT_bd PF06657.13 CBY23247.1 - 0.00038 20.9 5.1 0.00038 20.9 5.1 3.7 2 2 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 WXG100 PF06013.12 CBY23247.1 - 0.15 12.3 9.5 5 7.4 0.0 4.7 4 2 0 4 4 4 0 Proteins of 100 residues with WXG TACC_C PF05010.14 CBY23247.1 - 0.73 9.6 30.4 1.2 8.8 10.0 2.5 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ZapD PF07072.11 CBY23247.1 - 2.6 7.8 15.6 0.3 10.8 1.5 3.2 2 1 0 2 2 2 0 Cell division protein PspB PF06667.12 CBY23247.1 - 6.7 6.9 7.6 2.7 8.1 1.0 3.1 2 0 0 2 2 2 0 Phage shock protein B COG2 PF06148.11 CBY23247.1 - 8.7 6.4 18.0 0.62 10.2 2.8 3.5 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TRAM_LAG1_CLN8 PF03798.16 CBY23249.1 - 2.9e-17 63.1 14.1 3.9e-17 62.6 14.1 1.0 1 0 0 1 1 1 1 TLC domain DUF5090 PF17009.5 CBY23249.1 - 0.081 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) SPT2 PF08243.11 CBY23250.1 - 2.2e-06 28.2 11.2 2.2e-06 28.2 11.2 3.9 3 1 0 3 3 3 1 SPT2 chromatin protein zf-C2H2_jaz PF12171.8 CBY23251.1 - 2.4e-07 30.9 0.4 4.2e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY23251.1 - 1e-06 28.9 0.9 1.8e-06 28.1 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CBY23251.1 - 2.5e-05 23.9 1.1 5.8e-05 22.8 1.1 1.6 1 0 0 1 1 1 1 U1 zinc finger SNRNP27 PF08648.12 CBY23251.1 - 0.092 12.8 0.4 0.092 12.8 0.4 3.1 4 0 0 4 4 4 0 U4/U6.U5 small nuclear ribonucleoproteins Asp-B-Hydro_N PF05279.11 CBY23251.1 - 0.72 9.9 17.6 1.1 9.3 17.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 CBY23251.1 - 1.9 7.1 8.3 2.2 6.9 8.3 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CBY23251.1 - 3.3 7.4 14.3 4.5 7.0 14.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NUC153 PF08159.12 CBY23252.1 - 0.00013 21.7 5.1 0.00028 20.6 0.0 3.4 3 0 0 3 3 3 1 NUC153 domain DUF2096 PF09869.9 CBY23252.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) H_lectin PF09458.10 CBY23253.1 - 0.064 13.4 0.1 0.066 13.4 0.1 1.1 1 0 0 1 1 1 0 H-type lectin domain PhoLip_ATPase_C PF16212.5 CBY23254.1 - 2.4e-75 253.5 23.6 2.4e-75 253.5 23.6 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CBY23254.1 - 3.7e-14 53.5 1.0 2.8e-06 27.8 0.3 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY23254.1 - 5.4e-13 48.8 0.1 3.6e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBY23254.1 - 5.8e-07 29.2 0.0 1.6e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBY23254.1 - 0.00029 20.7 3.0 0.00046 20.0 0.6 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rdx PF10262.9 CBY23255.1 - 3.4e-06 27.2 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Rdx family Beach PF02138.18 CBY23256.1 - 2.4e-116 387.9 1.7 3.6e-116 387.4 0.4 1.8 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 CBY23256.1 - 2.1e-83 279.8 1.6 5.6e-83 278.4 1.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 CBY23256.1 - 2.6e-44 150.8 5.3 5.1e-44 149.9 5.3 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.6 CBY23256.1 - 1.2e-25 89.5 0.0 3.1e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 CBY23256.1 - 1.5e-09 38.2 0.0 5.9e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily ANAPC4_WD40 PF12894.7 CBY23256.1 - 0.01 16.1 0.0 0.085 13.2 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4800 PF16057.5 CBY23256.1 - 0.052 12.8 0.7 0.12 11.7 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) WD40 PF00400.32 CBY23256.1 - 0.69 10.9 5.9 59 4.8 0.0 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat Adenine_glyco PF03352.13 CBY23257.1 - 0.72 9.6 3.6 3.4 7.4 0.0 2.6 3 0 0 3 3 3 0 Methyladenine glycosylase Ribophorin_I PF04597.14 CBY23259.1 - 1.8e-115 386.7 2.3 2.4e-115 386.2 2.3 1.1 1 0 0 1 1 1 1 Ribophorin I Monooxygenase_B PF04744.12 CBY23259.1 - 0.084 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Monooxygenase subunit B protein Arf PF00025.21 CBY23260.1 - 1.2e-10 41.1 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 CBY23260.1 - 1.7e-05 25.1 0.4 2.7e-05 24.4 0.4 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 CBY23260.1 - 4.6e-05 22.9 0.0 6.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CBY23260.1 - 0.00013 22.1 0.5 0.00025 21.2 0.5 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBY23260.1 - 0.00031 20.8 0.1 0.0011 19.1 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 CBY23260.1 - 0.0004 20.0 0.4 0.012 15.2 0.2 2.1 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CBY23260.1 - 0.00051 20.0 1.1 0.011 15.7 0.1 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 CBY23260.1 - 0.00082 19.8 0.4 0.0015 19.0 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 CBY23260.1 - 0.003 17.2 0.7 0.013 15.1 0.2 2.1 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 CBY23260.1 - 0.0042 16.8 0.4 0.0077 16.0 0.4 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CBY23260.1 - 0.0067 16.0 0.2 0.015 14.8 0.2 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CBY23260.1 - 0.0071 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 CBY23260.1 - 0.01 15.4 0.2 0.042 13.4 0.2 1.8 1 1 0 1 1 1 0 Ras family Septin PF00735.18 CBY23260.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Septin Mg_chelatase PF01078.21 CBY23260.1 - 0.021 14.2 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CBY23260.1 - 0.033 13.9 0.1 0.045 13.5 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 CBY23260.1 - 0.034 13.9 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 CBY23260.1 - 0.035 13.5 0.2 0.082 12.3 0.1 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 CBY23260.1 - 0.041 14.4 0.0 0.048 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBY23260.1 - 0.049 13.6 0.0 0.093 12.6 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CBY23260.1 - 0.051 14.1 0.1 0.051 14.1 0.1 1.3 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CBY23260.1 - 0.055 13.4 0.2 0.12 12.3 0.2 1.5 2 0 0 2 2 2 0 RsgA GTPase DUF2075 PF09848.9 CBY23260.1 - 0.057 12.7 0.1 0.077 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sec3-PIP2_bind PF15277.6 CBY23260.1 - 0.058 13.5 0.2 2.4 8.3 0.2 2.2 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Mycobact_memb PF05423.13 CBY23260.1 - 0.064 13.2 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycobacterium membrane protein ATP_bind_1 PF03029.17 CBY23260.1 - 0.065 13.0 0.1 0.82 9.4 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 CBY23260.1 - 0.08 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 CBY23260.1 - 0.08 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 CBY23260.1 - 0.088 11.9 1.3 1.5 7.9 0.4 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_30 PF13604.6 CBY23260.1 - 0.13 12.0 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CBY23260.1 - 0.14 11.3 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 CBY23261.1 - 9.7e-65 218.5 0.2 2.5e-64 217.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23261.1 - 9.2e-46 156.2 0.0 1.5e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY23261.1 - 0.00017 21.1 0.0 0.00045 19.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY23261.1 - 0.00073 18.4 0.0 0.00073 18.4 0.0 3.8 3 1 0 3 3 3 1 Fungal protein kinase Cadherin PF00028.17 CBY23262.1 - 1.8e-05 25.1 0.9 0.061 13.8 0.0 4.4 4 0 0 4 4 4 2 Cadherin domain IBV_3C PF03620.13 CBY23262.1 - 0.15 12.6 1.2 0.36 11.3 1.2 1.6 1 0 0 1 1 1 0 IBV 3C protein PLAC8 PF04749.17 CBY23263.1 - 0.73 10.9 16.3 1.3 10.1 16.3 1.5 1 1 0 1 1 1 0 PLAC8 family Sulfatase PF00884.23 CBY23264.1 - 1.7e-49 168.9 0.3 1.9e-25 89.9 0.1 2.5 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.22 CBY23264.1 - 3.4e-06 26.9 0.0 0.0015 18.2 0.0 2.5 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase ASL_C2 PF14698.6 CBY23264.1 - 0.12 13.1 0.0 0.35 11.6 0.0 1.7 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal RBB1NT PF08169.11 CBY23265.1 - 0.047 13.8 0.1 0.091 12.9 0.1 1.5 1 0 0 1 1 1 0 RBB1NT (NUC162) domain OEP PF02321.18 CBY23265.1 - 0.15 11.9 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein dCache_3 PF14827.6 CBY23267.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase EF-hand_7 PF13499.6 CBY23268.1 - 6.2e-25 87.4 4.0 3.7e-16 59.3 0.5 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBY23268.1 - 6.1e-21 72.4 9.7 6.3e-06 25.4 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBY23268.1 - 1.7e-20 71.1 3.4 4.4e-05 23.1 0.1 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CBY23268.1 - 5.5e-13 48.5 13.0 2.8e-05 23.9 0.4 4.4 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY23268.1 - 3.3e-11 42.1 5.9 7.2e-05 22.1 0.2 4.4 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 CBY23268.1 - 2.4e-05 24.6 2.3 0.043 14.1 0.6 3.3 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY23268.1 - 0.00019 21.3 5.7 1.1 9.3 0.1 3.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CBY23268.1 - 0.062 13.2 4.1 17 5.3 0.1 3.7 1 1 2 4 4 4 0 Caleosin related protein DUF1679 PF07914.11 CBY23268.1 - 0.064 12.1 0.2 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_3 PF09069.11 CBY23268.1 - 0.068 13.6 0.0 0.45 11.0 0.0 2.0 2 1 0 2 2 2 0 EF-hand GPHH PF16905.5 CBY23268.1 - 0.099 12.4 0.1 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Pan3_PK PF18101.1 CBY23268.1 - 0.099 12.6 0.7 0.25 11.3 0.2 1.9 2 1 0 2 2 2 0 Pan3 Pseudokinase domain Homez PF11569.8 CBY23268.1 - 0.16 11.5 0.4 0.29 10.6 0.4 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeodomain PF00046.29 CBY23269.1 - 8.8e-33 111.9 5.2 2.5e-16 59.3 0.9 3.0 3 0 0 3 3 2 2 Homeodomain zf-met PF12874.7 CBY23269.1 - 2.4e-06 27.7 26.3 0.0048 17.3 0.4 7.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY23269.1 - 1.7e-05 25.0 33.6 0.4 11.1 0.9 8.2 6 1 1 9 9 9 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CBY23269.1 - 0.0001 22.5 5.7 0.0015 18.9 0.4 10.1 11 0 0 11 11 9 3 Zinc finger, C2H2 type Homeobox_KN PF05920.11 CBY23269.1 - 0.00013 21.8 0.2 0.0074 16.2 0.1 2.8 2 0 0 2 2 2 1 Homeobox KN domain zf_C2H2_ZHX PF18387.1 CBY23269.1 - 0.00025 20.6 17.0 0.14 11.8 0.1 6.6 6 0 0 6 6 6 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 CBY23269.1 - 0.00028 20.6 1.8 0.00062 19.5 0.7 6.8 8 0 0 8 8 7 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CBY23269.1 - 0.025 15.0 22.9 1.2 9.6 0.7 7.6 6 0 0 6 6 6 0 Zinc-finger double domain AKAP95 PF04988.12 CBY23269.1 - 0.03 14.6 0.0 0.03 14.6 0.0 6.0 6 1 0 7 7 6 0 A-kinase anchoring protein 95 (AKAP95) zf_C2H2_10 PF18414.1 CBY23269.1 - 0.84 9.2 7.3 3.3 7.3 0.0 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger Actin_micro PF17003.5 CBY23269.1 - 1.7 7.8 16.9 2.8 7.0 4.0 4.8 2 1 0 3 3 3 0 Putative actin-like family CpXC PF14353.6 CBY23269.1 - 1.9 8.6 15.4 12 5.9 0.0 5.7 6 0 0 6 6 5 0 CpXC protein DUF3449 PF11931.8 CBY23269.1 - 1.9 8.2 0.0 1.9 8.2 0.0 4.9 7 0 0 7 7 7 0 Domain of unknown function (DUF3449) zf-C2H2_9 PF16293.5 CBY23269.1 - 3.2 7.7 12.9 5.7 6.9 0.2 5.1 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) DUF2225 PF09986.9 CBY23269.1 - 3.7 7.2 11.4 0.45 10.2 2.5 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_4 PF13894.6 CBY23269.1 - 4 8.5 48.3 0.89 10.6 0.9 10.3 11 0 0 11 11 10 0 C2H2-type zinc finger zf-C2H2_12 PF18658.1 CBY23269.1 - 6.6 6.4 19.0 0.44 10.1 0.1 6.0 7 0 0 7 7 7 0 Zinc-finger C2H2-type TPR_1 PF00515.28 CBY23270.1 - 2.3e-05 24.0 2.6 0.089 12.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY23270.1 - 2.5e-05 24.1 3.3 0.69 10.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY23270.1 - 0.0032 17.1 0.3 1.1 9.1 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 CBY23270.1 - 0.011 16.0 0.5 0.069 13.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY23270.1 - 0.22 12.2 0.2 0.22 12.2 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY23270.1 - 0.3 11.3 4.0 1.3 9.2 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4355 PF14265.6 CBY23270.1 - 1.2 9.4 7.7 0.088 13.0 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DNA_photolyase PF00875.18 CBY23271.1 - 3e-30 105.4 0.0 4.6e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase DUF4259 PF14078.6 CBY23271.1 - 0.017 15.9 0.6 0.81 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) FAD_binding_7 PF03441.14 CBY23272.1 - 1.5e-47 161.7 0.8 1.7e-47 161.6 0.8 1.0 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Connexin PF00029.19 CBY23273.1 - 5.2e-58 196.6 5.8 1.5e-56 191.8 5.8 2.0 1 1 0 1 1 1 1 Connexin TRAP-gamma PF07074.12 CBY23273.1 - 0.019 14.6 0.6 0.019 14.6 0.6 1.8 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) STATa_Ig PF18214.1 CBY23273.1 - 0.15 12.1 0.6 0.25 11.3 0.4 1.5 1 1 0 1 1 1 0 STATa Immunoglobulin-like domain OrfB_IS605 PF01385.19 CBY23273.1 - 0.15 12.3 1.7 0.24 11.6 1.4 1.5 1 1 0 1 1 1 0 Probable transposase Presenilin PF01080.17 CBY23273.1 - 0.18 10.6 0.8 0.29 9.9 0.8 1.3 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CBY23273.1 - 0.28 10.5 9.4 0.54 9.6 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3899 PF13038.6 CBY23273.1 - 0.36 11.4 3.0 32 5.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) DUF1043 PF06295.12 CBY23273.1 - 0.54 10.3 12.1 4.4 7.3 12.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) V_ATPase_I PF01496.19 CBY23273.1 - 3.9 5.3 11.4 2.1 6.2 8.3 1.8 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family HTH_37 PF13744.6 CBY23273.1 - 4.7 7.2 6.4 0.36 10.8 1.5 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_S49_N PF08496.10 CBY23273.1 - 7.1 6.7 13.8 4 7.5 2.7 2.3 1 1 1 2 2 2 0 Peptidase family S49 N-terminal OmpH PF03938.14 CBY23273.1 - 9 6.6 18.7 14 6.0 18.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MFS_1 PF07690.16 CBY23274.1 - 6e-24 84.6 22.7 6e-24 84.6 22.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Transgly_assoc PF04226.13 CBY23274.1 - 0.12 12.6 7.5 1.6 9.1 6.0 3.4 2 1 0 2 2 2 0 Transglycosylase associated protein TMEM70 PF06979.12 CBY23275.1 - 3.7e-12 46.8 1.4 4.6e-12 46.5 1.4 1.1 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Transposase_31 PF04754.12 CBY23275.1 - 0.0038 16.8 0.2 0.0063 16.1 0.2 1.6 1 1 0 1 1 1 1 Putative transposase, YhgA-like SURF1 PF02104.15 CBY23276.1 - 2.8e-30 105.9 0.0 3.2e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Peptidase_M14 PF00246.24 CBY23277.1 - 2.5e-15 57.0 0.0 4.8e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 CBY23277.1 - 5.9e-13 49.1 0.2 1.3e-12 48.0 0.2 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 CBY23277.1 - 0.12 11.4 0.1 0.25 10.4 0.1 1.6 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Ribosom_S12_S23 PF00164.25 CBY23278.1 - 2.3e-17 62.7 0.3 4.1e-17 61.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 GTP_EFTU PF00009.27 CBY23279.1 - 1.7e-21 76.7 0.0 2.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CBY23279.1 - 8.7e-12 45.3 0.1 2.9e-11 43.6 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY23279.1 - 6.3e-05 23.0 0.9 0.0012 18.9 0.2 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBY23279.1 - 0.00011 21.9 0.0 1.1 8.9 0.0 3.3 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D3 PF03143.17 CBY23279.1 - 0.00028 21.1 0.0 0.00058 20.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain RsgA_GTPase PF03193.16 CBY23279.1 - 0.003 17.5 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 CBY23279.1 - 0.0095 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Septin Arf PF00025.21 CBY23279.1 - 0.078 12.4 0.0 21 4.5 0.0 3.1 2 1 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 CBY23279.1 - 0.098 12.7 0.1 0.71 9.9 0.1 2.2 1 1 1 2 2 2 0 Dynamin family USP7_ICP0_bdg PF12436.8 CBY23280.1 - 3.3e-58 196.9 0.0 6.7e-58 195.8 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 CBY23280.1 - 1.8e-49 168.6 0.2 1.8e-49 168.6 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CBY23280.1 - 1.4e-38 132.7 0.5 1.4e-38 132.7 0.5 3.1 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 CBY23280.1 - 2.3e-24 86.6 0.0 8e-24 84.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 CBY23280.1 - 1.7e-12 47.5 4.4 1.9e-12 47.4 0.0 3.4 5 0 0 5 5 5 1 MATH domain Peptidase_C98 PF15499.6 CBY23280.1 - 0.072 12.5 0.2 19 4.6 0.0 3.0 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Fib_alpha PF08702.10 CBY23281.1 - 0.021 15.0 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-C2H2_jaz PF12171.8 CBY23281.1 - 0.048 14.0 0.7 0.13 12.6 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CBY23281.1 - 0.084 13.4 0.1 0.25 11.9 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type E1_dh PF00676.20 CBY23283.1 - 1.6e-95 319.5 0.1 1.9e-95 319.3 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 CBY23283.1 - 0.0025 16.8 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 CBY23283.1 - 0.0026 17.0 0.0 0.0061 15.8 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 CBY23283.1 - 0.038 13.8 0.1 0.094 12.5 0.1 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Foie-gras_1 PF11817.8 CBY23286.1 - 4.2e-18 65.9 0.3 7.6e-18 65.0 0.3 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Coatamer_beta_C PF07718.12 CBY23286.1 - 0.022 14.7 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Coatomer beta C-terminal region Spo0M PF07070.11 CBY23286.1 - 0.18 11.3 0.1 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 SpoOM protein RNA_pol_Rpb2_7 PF04560.20 CBY23286.1 - 0.33 11.4 1.5 1.7 9.1 0.2 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 7 zf-CCCH PF00642.24 CBY23287.1 - 1.9e-20 72.2 16.6 2e-11 43.5 2.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY23287.1 - 2.5e-10 40.1 20.3 1.9e-05 24.6 4.9 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CBY23287.1 - 1.3e-07 31.2 15.0 5.5e-05 22.8 1.6 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CBY23287.1 - 0.0008 20.1 12.1 0.085 13.6 2.4 2.6 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 CBY23287.1 - 0.036 14.6 14.9 0.08 13.4 1.1 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RF-1 PF00472.20 CBY23288.1 - 3e-08 33.6 2.3 3.8e-08 33.3 1.3 1.7 1 1 0 1 1 1 1 RF-1 domain PLAC8 PF04749.17 CBY23289.1 - 3e-17 63.4 15.9 3.4e-17 63.2 15.9 1.0 1 0 0 1 1 1 1 PLAC8 family cNMP_binding PF00027.29 CBY23291.1 - 4.9e-09 36.1 0.0 8.7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HnRNP_M PF11532.8 CBY23291.1 - 0.48 10.7 4.9 0.97 9.7 4.9 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M Focal_AT PF03623.13 CBY23292.1 - 6.2e-41 139.5 3.4 8.3e-41 139.1 3.4 1.2 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase_Tyr PF07714.17 CBY23293.1 - 1.3e-87 293.4 1.2 2.3e-87 292.6 0.4 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CBY23293.1 - 2.8e-45 154.8 0.3 5.3e-45 153.9 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain FERM_M PF00373.18 CBY23293.1 - 6.5e-09 36.2 3.8 1.1e-08 35.5 1.4 2.3 2 1 0 2 2 2 1 FERM central domain FAD_binding_6 PF00970.24 CBY23293.1 - 0.0087 16.4 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Pkinase_fungal PF17667.1 CBY23293.1 - 0.027 13.3 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CBY23293.1 - 0.063 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GspL_C PF12693.7 CBY23293.1 - 0.11 12.3 0.4 0.21 11.4 0.4 1.3 1 0 0 1 1 1 0 GspL periplasmic domain Ras PF00071.22 CBY23294.1 - 1.9e-62 209.6 0.0 2.3e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY23294.1 - 4.1e-33 114.1 0.0 6.3e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY23294.1 - 4.8e-13 48.9 0.0 6e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY23294.1 - 0.0001 22.4 0.0 0.00017 21.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY23294.1 - 0.00045 20.2 0.0 0.4 10.6 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBY23294.1 - 0.00068 19.1 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY23294.1 - 0.00092 18.8 0.1 0.0052 16.3 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CBY23294.1 - 0.013 15.7 0.1 0.53 10.6 0.0 2.4 2 1 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CBY23294.1 - 0.084 12.6 0.0 0.098 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 CBY23294.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SEP PF08059.13 CBY23295.1 - 6.8e-09 36.2 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CBY23295.1 - 0.0021 18.2 0.0 0.071 13.3 0.0 2.5 2 0 0 2 2 2 1 UBX domain FERM_N PF09379.10 CBY23295.1 - 0.029 14.3 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 FERM N-terminal domain Sugarporin_N PF11471.8 CBY23295.1 - 0.084 12.8 5.2 0.15 12.0 5.2 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension TPH PF13868.6 CBY23296.1 - 3e-18 65.5 92.0 3e-18 65.5 92.0 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain LRRFIP PF09738.9 CBY23297.1 - 1.3e-86 290.7 43.9 5.8e-76 255.8 17.3 3.0 2 1 1 3 3 3 2 LRRFIP family CENP-F_leu_zip PF10473.9 CBY23297.1 - 0.0097 15.9 22.9 0.0097 15.9 22.9 4.4 3 2 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_14 PF17959.1 CBY23297.1 - 0.94 9.9 7.9 2.2 8.7 0.1 3.6 2 1 1 3 3 3 0 EF-hand domain DUF2946 PF11162.8 CBY23298.1 - 0.2 12.4 2.1 0.37 11.5 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) zf-C2H2 PF00096.26 CBY23299.1 - 1.8e-12 46.9 17.7 2e-06 27.9 2.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY23299.1 - 2.5e-11 43.4 22.2 0.00018 22.1 1.8 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 CBY23299.1 - 2.5e-06 27.2 0.3 9.5e-06 25.4 0.3 2.0 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 CBY23299.1 - 2.5e-05 24.5 15.8 0.25 11.7 4.1 3.6 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CBY23299.1 - 2.7e-05 24.0 17.2 0.0032 17.4 1.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBY23299.1 - 7.2e-05 23.0 6.3 7.2e-05 23.0 6.3 3.0 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CBY23299.1 - 0.00015 22.0 22.4 0.00023 21.4 0.2 5.6 5 0 0 5 5 5 1 Zinc-finger double domain Trm112p PF03966.16 CBY23299.1 - 0.00019 22.0 0.0 0.51 11.0 0.0 3.0 2 1 0 2 2 2 2 Trm112p-like protein zf-C2H2_11 PF16622.5 CBY23299.1 - 0.00075 19.2 17.1 0.011 15.5 0.9 3.8 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CBY23299.1 - 0.0012 19.0 11.4 0.021 15.1 0.3 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 CBY23299.1 - 0.0013 18.4 0.8 0.0041 16.9 0.8 1.8 1 0 0 1 1 1 1 GAGA factor zf-met PF12874.7 CBY23299.1 - 0.0034 17.7 12.7 0.019 15.3 0.1 4.0 4 0 0 4 4 3 1 Zinc-finger of C2H2 type LIM PF00412.22 CBY23299.1 - 0.0053 17.0 7.0 0.0062 16.7 3.1 2.6 2 0 0 2 2 2 1 LIM domain zf-C2H2_3rep PF18868.1 CBY23299.1 - 0.006 17.3 6.8 0.13 12.9 5.3 2.7 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 CBY23299.1 - 0.0093 16.0 4.6 0.093 12.8 0.7 2.5 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TRAF6_Z2 PF18048.1 CBY23299.1 - 0.042 13.9 1.9 0.18 11.9 1.9 2.1 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 Spt46 PF17734.1 CBY23299.1 - 0.047 13.5 0.5 0.047 13.5 0.5 2.8 2 1 0 3 3 3 0 Spermatogenesis-associated protein 46 C1_4 PF07975.12 CBY23299.1 - 0.072 13.3 1.1 0.072 13.3 1.1 2.9 2 1 1 3 3 2 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 CBY23299.1 - 0.089 12.7 7.7 6.4 6.8 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 CBY23299.1 - 0.14 12.1 6.4 0.52 10.2 0.1 3.0 3 0 0 3 3 2 0 RNA polymerases M/15 Kd subunit DUF2256 PF10013.9 CBY23299.1 - 0.27 11.4 0.2 0.27 11.4 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-C2H2_12 PF18112.1 CBY23299.1 - 0.31 11.5 0.3 0.31 11.5 0.3 3.3 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_8 PF15909.5 CBY23299.1 - 0.32 11.3 7.9 0.65 10.3 3.1 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon Elf1 PF05129.13 CBY23299.1 - 0.48 10.5 10.2 0.92 9.6 0.3 3.4 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_9 PF16293.5 CBY23299.1 - 0.62 9.9 5.5 0.41 10.5 0.3 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) CpXC PF14353.6 CBY23299.1 - 0.72 9.9 11.3 15 5.6 4.2 3.7 2 1 1 3 3 3 0 CpXC protein C1_2 PF03107.16 CBY23299.1 - 1.5 9.2 13.6 0.59 10.5 2.6 3.7 2 1 1 3 3 3 0 C1 domain zf-BED PF02892.15 CBY23299.1 - 7 6.8 14.9 0.62 10.1 1.4 3.5 1 1 1 2 2 2 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 CBY23299.1 - 8.8 6.4 10.8 1.8 8.6 1.1 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain RF-1 PF00472.20 CBY23300.1 - 2e-17 63.2 0.4 2.8e-17 62.7 0.4 1.1 1 0 0 1 1 1 1 RF-1 domain PYST-C1 PF09690.10 CBY23300.1 - 0.97 9.2 9.7 6.9 6.5 0.0 2.4 2 1 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) Per1 PF04080.13 CBY23301.1 - 2.3e-41 142.3 2.3 2.8e-41 142.0 2.3 1.0 1 0 0 1 1 1 1 Per1-like family INSIG PF07281.12 CBY23301.1 - 0.099 12.3 0.8 0.11 12.1 0.1 1.4 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) ThiF PF00899.21 CBY23302.1 - 6.5e-24 84.6 0.0 1e-23 84.0 0.0 1.3 1 1 0 1 1 1 1 ThiF family ArgoMid PF16487.5 CBY23302.1 - 0.17 12.2 0.0 0.49 10.7 0.0 1.8 1 0 0 1 1 1 0 Mid domain of argonaute FXa_inhibition PF14670.6 CBY23304.1 - 8.7e-06 25.9 8.1 8.7e-06 25.9 8.1 4.6 3 1 0 4 4 4 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY23304.1 - 0.00019 21.3 1.1 0.00019 21.3 1.1 4.9 4 0 0 4 4 4 1 Complement Clr-like EGF-like EGF PF00008.27 CBY23304.1 - 0.62 10.4 21.3 1.9 8.9 0.3 5.1 4 1 0 4 4 4 0 EGF-like domain EGF_alliinase PF04863.13 CBY23304.1 - 3.4 8.2 13.7 1.1 9.8 0.4 3.5 3 0 0 3 3 3 0 Alliinase EGF-like domain EGF_2 PF07974.13 CBY23304.1 - 4 7.9 32.8 0.12 12.7 1.5 4.7 4 0 0 4 4 4 0 EGF-like domain SAM_1 PF00536.30 CBY23305.1 - 9.5e-24 83.6 4.0 8.1e-11 42.2 0.4 3.4 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY23305.1 - 8.6e-20 70.6 3.0 7.7e-06 25.9 0.0 3.4 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) PhoPQ_related PF10142.9 CBY23306.1 - 6e-36 123.9 0.0 7.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Mucin PF01456.17 CBY23306.1 - 0.0032 17.4 24.3 0.0061 16.6 24.3 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.11 CBY23306.1 - 0.12 10.6 20.3 0.18 9.9 20.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 CBY23306.1 - 9 4.3 13.5 13 3.8 13.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Toxin_YhaV PF11663.8 CBY23307.1 - 0.0074 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Toxin with endonuclease activity, of toxin-antitoxin system Tubulin_C PF03953.17 CBY23309.1 - 5.4e-16 58.9 0.4 1.4e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin PF00091.25 CBY23310.1 - 1.3e-68 231.1 0.0 1.5e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 CBY23310.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Aa_trans PF01490.18 CBY23312.1 - 4.4e-75 252.9 21.6 5.1e-75 252.7 21.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein WD40 PF00400.32 CBY23313.1 - 9.2e-33 111.8 24.0 6.6e-09 36.3 0.6 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY23313.1 - 1.6e-12 47.5 4.6 0.097 13.0 0.1 6.3 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY23313.1 - 2.9e-06 27.3 0.4 0.37 10.6 0.1 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBY23313.1 - 4.6e-06 25.8 3.8 0.021 13.8 1.4 4.1 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY23313.1 - 0.00014 20.7 6.3 0.82 8.2 0.0 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 APG6_N PF17675.1 CBY23313.1 - 0.025 15.1 10.1 0.064 13.8 9.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Nbas_N PF15492.6 CBY23313.1 - 0.034 13.5 0.1 0.48 9.7 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal ZapB PF06005.12 CBY23313.1 - 0.057 13.9 7.4 1.2 9.6 3.9 2.4 2 0 0 2 2 2 0 Cell division protein ZapB DUF5082 PF16888.5 CBY23313.1 - 0.1 12.9 3.8 0.25 11.6 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 CBY23313.1 - 0.54 9.5 5.4 2.3 7.5 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 CBY23313.1 - 0.55 9.9 11.4 0.28 10.9 9.1 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 YabA PF06156.13 CBY23313.1 - 0.91 10.2 7.9 4.8 7.9 0.6 2.8 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 CBY23313.1 - 2.8 6.5 7.8 4.2 5.9 7.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Proteasome PF00227.26 CBY23314.1 - 1.5e-45 155.1 0.2 1.8e-45 154.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CBY23314.1 - 1e-08 34.4 0.2 1e-08 34.4 0.2 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal zf-C2H2 PF00096.26 CBY23315.1 - 1.9e-14 53.2 28.8 0.0002 21.7 0.6 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY23315.1 - 9.7e-14 50.9 28.7 0.00029 21.4 0.3 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY23315.1 - 4.1e-06 27.0 29.1 0.00044 20.6 1.1 6.1 6 0 0 6 6 6 2 Zinc-finger double domain zf-met PF12874.7 CBY23315.1 - 0.00022 21.5 6.9 0.27 11.7 0.1 4.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-CHC2 PF01807.20 CBY23315.1 - 0.00058 19.6 1.6 0.0021 17.8 0.7 2.5 1 1 1 2 2 2 1 CHC2 zinc finger HypA PF01155.19 CBY23315.1 - 0.0046 17.0 6.3 0.19 11.8 3.3 2.8 2 1 1 3 3 3 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_jaz PF12171.8 CBY23315.1 - 0.012 15.9 19.0 0.13 12.6 0.1 5.3 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CBY23315.1 - 0.012 15.9 17.9 0.025 14.9 1.4 4.0 3 1 1 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding ARS2 PF04959.13 CBY23315.1 - 0.015 15.7 1.8 0.015 15.7 1.8 3.6 3 1 1 4 4 4 0 Arsenite-resistance protein 2 zf-C2HE PF16278.5 CBY23315.1 - 0.026 15.0 10.9 0.22 12.0 1.8 3.2 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 CBY23315.1 - 0.12 12.5 22.7 0.58 10.2 0.1 5.1 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CBY23315.1 - 0.14 12.1 11.0 7.8 6.5 0.2 4.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 CBY23315.1 - 0.21 11.7 8.5 3.2 8.0 0.4 3.6 3 0 0 3 3 3 0 Zinc ribbon domain zf-BED PF02892.15 CBY23315.1 - 0.27 11.3 19.3 0.54 10.3 1.8 4.4 2 1 1 3 3 3 0 BED zinc finger Elf1 PF05129.13 CBY23315.1 - 0.28 11.2 9.9 0.34 11.0 0.8 3.3 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_12 PF18658.1 CBY23315.1 - 0.31 10.6 10.7 0.25 10.9 0.4 3.6 3 1 1 4 4 4 0 Zinc-finger C2H2-type Cript PF10235.9 CBY23315.1 - 0.36 11.4 11.0 7.1 7.3 4.1 3.2 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT zf_UBZ PF18439.1 CBY23315.1 - 1.4 8.6 12.0 0.21 11.2 0.4 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 CBY23315.1 - 1.7 8.5 16.0 5.8 6.8 0.1 5.0 5 0 0 5 5 5 0 zinc-finger C2H2-type Sgf11 PF08209.11 CBY23315.1 - 2.1 8.0 10.4 0.71 9.5 0.1 3.9 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-Sec23_Sec24 PF04810.15 CBY23315.1 - 2.5 8.2 4.3 9.1 6.4 0.1 3.1 3 0 0 3 3 2 0 Sec23/Sec24 zinc finger PHD PF00628.29 CBY23315.1 - 2.5 8.1 7.7 0.59 10.1 1.3 2.8 3 0 0 3 3 3 0 PHD-finger zf-C2H2_3rep PF18868.1 CBY23315.1 - 2.8 8.6 22.5 0.9 10.2 3.1 4.6 1 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats DUF3449 PF11931.8 CBY23315.1 - 3.2 7.5 13.2 0.91 9.3 4.6 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF3449) UAA PF08449.11 CBY23316.1 - 1.3e-80 270.8 26.6 1.9e-80 270.3 26.6 1.2 1 0 0 1 1 1 1 UAA transporter family 7tm_1 PF00001.21 CBY23317.1 - 4.6e-28 98.3 6.2 4.9e-17 62.1 0.4 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CBY23317.1 - 0.00069 19.3 3.8 0.00069 19.3 3.8 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CBY23317.1 - 0.0024 17.3 8.4 0.0049 16.3 1.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx LZ3wCH PF18517.1 CBY23317.1 - 0.22 11.6 0.3 0.38 10.9 0.3 1.3 1 0 0 1 1 1 0 Leucine zipper with capping helix domain 7tm_4 PF13853.6 CBY23317.1 - 0.38 10.4 5.1 4.4 7.0 0.2 2.9 3 0 0 3 3 3 0 Olfactory receptor Ank_5 PF13857.6 CBY23318.1 - 1.2e-05 25.5 0.2 0.00099 19.4 0.2 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY23318.1 - 0.00012 22.5 0.1 0.023 15.3 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY23318.1 - 0.00062 20.3 0.1 0.015 15.9 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY23318.1 - 0.055 13.9 0.7 0.96 10.0 0.3 2.7 2 1 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 CBY23318.1 - 0.057 14.0 0.2 2 9.3 0.0 2.9 3 1 0 3 3 3 0 Ankyrin repeat PQQ_2 PF13360.6 CBY23319.1 - 2.9e-14 53.3 0.0 1.1e-06 28.4 0.0 2.9 2 2 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 CBY23319.1 - 6.4e-14 51.1 0.5 0.089 12.8 0.0 6.6 7 0 0 7 7 7 4 PQQ enzyme repeat PQQ_3 PF13570.6 CBY23319.1 - 8.9e-10 38.8 0.3 0.035 14.6 0.0 6.9 7 1 0 7 7 7 1 PQQ-like domain BBS2_N PF14781.6 CBY23319.1 - 0.073 13.0 0.0 7.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Ig_4 PF16680.5 CBY23322.1 - 0.0016 18.6 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Transglut_N PF00868.20 CBY23323.1 - 1.5e-25 89.8 0.0 4.8e-25 88.2 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 CBY23323.1 - 3.8e-17 62.4 0.0 8.2e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 CBY23323.1 - 9.7e-16 58.2 0.4 2e-15 57.2 0.4 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sushi PF00084.20 CBY23326.1 - 7.4e-07 29.7 43.3 0.0019 18.7 0.8 6.1 6 0 0 6 6 6 5 Sushi repeat (SCR repeat) EGF_3 PF12947.7 CBY23327.1 - 7.9e-19 67.6 87.9 3.3e-06 27.2 16.3 7.2 7 0 0 7 7 7 6 EGF domain EGF_MSP1_1 PF12946.7 CBY23327.1 - 1.4e-10 41.1 73.9 6.3e-08 32.5 11.1 6.6 6 0 0 6 6 6 5 MSP1 EGF domain 1 EGF PF00008.27 CBY23327.1 - 3.7e-06 27.1 60.6 0.003 17.8 3.9 6.9 6 0 0 6 6 6 5 EGF-like domain EGF_CA PF07645.15 CBY23327.1 - 0.00011 22.3 91.1 0.011 15.9 9.2 7.8 5 2 2 7 7 7 4 Calcium-binding EGF domain cEGF PF12662.7 CBY23327.1 - 0.0099 15.8 4.0 0.0099 15.8 4.0 6.2 6 0 0 6 6 6 4 Complement Clr-like EGF-like Ion_trans_2 PF07885.16 CBY23328.1 - 7.6e-06 25.8 3.7 6.7e-05 22.8 3.7 2.0 1 1 0 1 1 1 1 Ion channel DUF2956 PF11169.8 CBY23328.1 - 0.03 14.5 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Ion_trans_2 PF07885.16 CBY23329.1 - 4.9e-18 64.9 1.4 4.9e-18 64.9 1.4 2.5 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 CBY23329.1 - 0.00022 20.5 2.8 0.00022 20.5 2.8 1.7 2 0 0 2 2 2 1 Ion transport protein DUF2178 PF09946.9 CBY23329.1 - 0.028 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) SET PF00856.28 CBY23330.1 - 2e-12 47.9 0.1 5.2e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 SET domain Sas10 PF09368.10 CBY23330.1 - 0.11 12.9 3.4 0.28 11.7 3.4 1.6 1 0 0 1 1 1 0 Sas10 C-terminal domain DUF5406 PF17400.2 CBY23331.1 - 0.056 13.9 0.2 0.14 12.6 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5406) SAGA-Tad1 PF12767.7 CBY23331.1 - 7.4 6.2 10.3 61 3.2 10.3 2.0 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NAM-associated PF14303.6 CBY23332.1 - 0.028 15.2 6.9 0.065 13.9 6.9 1.7 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Alk_phosphatase PF00245.20 CBY23333.1 - 2.2e-112 376.0 0.0 2.5e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase NCBP3 PF10309.9 CBY23333.1 - 0.014 15.2 0.1 0.04 13.8 0.1 1.7 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Metalloenzyme PF01676.18 CBY23333.1 - 0.044 13.2 0.0 0.089 12.1 0.0 1.6 1 1 0 1 1 1 0 Metalloenzyme superfamily STT3 PF02516.14 CBY23334.1 - 1.2e-99 334.5 33.3 1.2e-99 334.5 33.3 2.4 2 1 0 2 2 2 1 Oligosaccharyl transferase STT3 subunit OST3_OST6 PF04756.13 CBY23334.1 - 1.1e-21 77.4 3.1 1.1e-21 77.4 3.1 2.8 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family LRR_8 PF13855.6 CBY23335.1 - 5.3e-32 109.4 18.6 1.1e-08 34.7 0.9 7.6 6 2 2 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 CBY23335.1 - 2e-20 72.5 17.1 0.00015 22.0 0.1 8.1 7 3 3 10 10 9 6 Leucine Rich repeats (2 copies) TIR PF01582.20 CBY23335.1 - 1.9e-05 24.5 0.1 3.5e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 TIR domain YajC PF02699.15 CBY23335.1 - 0.00017 21.4 0.1 0.00038 20.3 0.1 1.5 1 0 0 1 1 1 1 Preprotein translocase subunit TIR_2 PF13676.6 CBY23335.1 - 0.00056 20.5 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 CBY23335.1 - 0.008 15.7 6.9 0.67 9.4 1.0 3.4 2 1 0 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 CBY23335.1 - 0.009 16.0 17.9 4.9 7.5 0.1 8.4 9 0 0 9 9 9 1 Leucine Rich repeat LapA_dom PF06305.11 CBY23335.1 - 0.027 14.3 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain LRR_1 PF00560.33 CBY23335.1 - 0.087 13.4 19.5 3.9 8.4 1.2 8.8 8 4 1 9 9 9 0 Leucine Rich Repeat EphA2_TM PF14575.6 CBY23335.1 - 0.1 13.5 0.1 0.31 12.0 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRRNT PF01462.18 CBY23335.1 - 0.18 11.5 5.4 0.052 13.2 1.4 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DUF2070 PF09843.9 CBY23336.1 - 0.19 9.9 11.4 0.23 9.7 11.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Condensation PF00668.20 CBY23337.1 - 0.019 13.6 0.0 0.034 12.8 0.0 1.3 1 0 0 1 1 1 0 Condensation domain ACC_central PF08326.12 CBY23337.1 - 0.05 11.8 0.1 0.069 11.3 0.1 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region DUF190 PF02641.15 CBY23337.1 - 0.14 12.5 0.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized ACR, COG1993 PDEase_I PF00233.19 CBY23339.1 - 1.2e-72 244.5 5.5 1.7e-72 244.0 5.5 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 CBY23339.1 - 2.5e-06 27.2 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal APC_u5 PF16630.5 CBY23340.1 - 2.9 9.0 12.5 1.7 9.7 3.8 2.6 2 0 0 2 2 2 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs DUF908 PF06012.12 CBY23340.1 - 3.8 6.8 17.8 4.4 6.6 7.6 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Phospholip_A2_1 PF00068.19 CBY23341.1 - 2.5e-07 31.1 1.2 2.6e-07 31.1 0.1 1.5 2 0 0 2 2 2 1 Phospholipase A2 DUF3938 PF13074.6 CBY23342.1 - 0.017 15.3 0.5 0.041 14.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Acyl_transf_3 PF01757.22 CBY23342.1 - 0.043 12.9 0.2 0.055 12.5 0.2 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF1624 PF07786.12 CBY23342.1 - 0.084 12.4 0.4 0.12 11.9 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1624) EF-hand_1 PF00036.32 CBY23343.1 - 7e-08 31.5 1.0 0.0002 20.7 0.1 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY23343.1 - 3.7e-06 27.3 0.9 0.013 15.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY23343.1 - 2e-05 24.1 5.3 0.0017 18.2 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY23343.1 - 0.00034 20.0 0.1 0.00034 20.0 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY23343.1 - 0.00046 20.0 0.2 0.0087 15.9 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair Trypsin PF00089.26 CBY23344.1 - 6.2e-34 117.7 0.1 6.2e-34 117.7 0.1 1.7 2 1 0 2 2 2 1 Trypsin cEGF PF12662.7 CBY23344.1 - 6.5e-06 26.0 2.5 6.5e-06 26.0 2.5 3.0 3 0 0 3 3 3 1 Complement Clr-like EGF-like Trypsin_2 PF13365.6 CBY23344.1 - 1.9e-05 25.6 0.0 3.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain FXa_inhibition PF14670.6 CBY23344.1 - 0.00022 21.4 4.5 0.00022 21.4 4.5 3.3 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site Antimicrobial25 PF16839.5 CBY23344.1 - 4.2 7.5 15.9 0.45 10.6 5.4 2.8 2 0 0 2 2 2 0 Nematode antimicrobial peptide Lectin_C PF00059.21 CBY23345.1 - 3.9e-06 27.6 7.2 9.6e-06 26.3 4.7 2.5 2 1 0 2 2 2 1 Lectin C-type domain GSHPx PF00255.19 CBY23346.1 - 0.00039 20.0 0.0 0.00046 19.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 CBY23347.1 - 1.1e-21 76.4 0.0 2.4e-21 75.3 0.0 1.5 2 0 0 2 2 2 1 Glutathione peroxidase Dimer_Tnp_hAT PF05699.14 CBY23348.1 - 0.046 13.5 0.4 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region PXA PF02194.15 CBY23348.1 - 0.053 13.5 0.1 0.26 11.3 0.0 2.0 1 1 1 2 2 2 0 PXA domain Phosphodiest PF01663.22 CBY23349.1 - 1.7e-57 195.7 0.0 2.5e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 CBY23349.1 - 1.3e-05 25.5 9.5 3.4e-05 24.2 9.5 1.7 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.23 CBY23349.1 - 0.068 12.6 0.0 0.44 9.9 0.0 2.3 1 1 0 1 1 1 0 Sulfatase Orbi_VP1 PF05788.12 CBY23350.1 - 0.006 14.3 0.2 0.006 14.3 0.2 1.0 1 0 0 1 1 1 1 Orbivirus RNA-dependent RNA polymerase (VP1) MotB_plug PF13677.6 CBY23352.1 - 0.025 14.1 0.3 0.081 12.5 0.2 2.0 1 1 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Radial_spoke_3 PF06098.11 CBY23352.1 - 0.058 12.7 2.7 0.11 11.8 2.7 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 DUF350 PF03994.14 CBY23352.1 - 0.21 11.8 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) DivIC PF04977.15 CBY23352.1 - 5.5 6.8 9.9 2.4 8.0 2.2 2.5 2 0 0 2 2 2 0 Septum formation initiator Troponin PF00992.20 CBY23353.1 - 2.9e-07 30.9 26.6 3.1e-07 30.7 26.6 1.0 1 0 0 1 1 1 1 Troponin DUF4638 PF15472.6 CBY23353.1 - 0.15 11.8 12.5 0.16 11.7 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) THAP PF05485.12 CBY23353.1 - 1.4 9.9 6.4 1 10.3 4.3 2.0 1 1 1 2 2 2 0 THAP domain Asp-B-Hydro_N PF05279.11 CBY23353.1 - 1.5 8.9 16.3 1.6 8.8 16.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4776 PF16003.5 CBY23353.1 - 1.7 7.6 14.6 2 7.3 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF3340 PF11818.8 CBY23353.1 - 1.8 8.7 20.9 2.2 8.4 20.9 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Macoilin PF09726.9 CBY23353.1 - 2.6 6.5 18.6 2.8 6.4 18.6 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 CBY23353.1 - 5.4 6.1 5.3 5.2 6.2 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rtf2 PF04641.12 CBY23353.1 - 8.4 5.7 17.8 9.6 5.5 17.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger BUD22 PF09073.10 CBY23354.1 - 0.22 10.8 16.0 0.25 10.6 16.0 1.0 1 0 0 1 1 1 0 BUD22 GEMIN8 PF15348.6 CBY23354.1 - 1.4 9.2 5.5 1.8 8.8 5.5 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 SDA1 PF05285.12 CBY23354.1 - 2.1 7.7 18.1 2.4 7.5 18.1 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 CBY23354.1 - 2.2 6.3 22.6 2.4 6.1 22.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SURF2 PF05477.11 CBY23354.1 - 3.1 7.4 8.4 3.7 7.2 8.4 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Myc_N PF01056.18 CBY23354.1 - 3.9 7.3 12.0 2.8 7.8 10.7 1.4 1 1 0 1 1 1 0 Myc amino-terminal region Y_phosphatase PF00102.27 CBY23355.1 - 4.5e-68 229.3 0.2 1e-67 228.2 0.1 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBY23355.1 - 0.21 11.4 1.9 0.51 10.2 0.9 2.2 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain ATP-gua_Ptrans PF00217.19 CBY23356.1 - 2.5e-76 255.9 0.0 3.1e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY23356.1 - 8.8e-25 86.9 0.0 1.5e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain PAD_M PF08527.10 CBY23357.1 - 0.0062 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain TSP_1 PF00090.19 CBY23358.1 - 1.5e-48 162.7 134.1 6.7e-09 35.8 9.4 10.6 10 0 0 10 10 10 9 Thrombospondin type 1 domain cEGF PF12662.7 CBY23358.1 - 3e-08 33.4 20.3 1e-06 28.5 1.5 4.8 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY23358.1 - 4.3e-08 33.2 21.3 1.3e-07 31.6 7.5 6.9 5 1 1 6 6 6 2 Calcium-binding EGF domain EGF_3 PF12947.7 CBY23358.1 - 2e-06 27.9 33.2 0.00023 21.3 2.5 4.9 3 0 0 3 3 3 3 EGF domain hEGF PF12661.7 CBY23358.1 - 0.00041 20.9 30.1 0.016 15.8 3.6 5.8 4 0 0 4 4 4 3 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY23358.1 - 0.0031 17.8 2.8 0.0031 17.8 2.8 8.0 6 1 2 8 8 8 2 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY23358.1 - 0.0081 16.2 2.1 0.0081 16.2 2.1 6.4 7 0 0 7 7 7 3 MSP1 EGF domain 1 EGF PF00008.27 CBY23358.1 - 0.025 14.9 44.3 0.063 13.6 4.8 6.1 5 0 0 5 5 5 0 EGF-like domain DUF2207 PF09972.9 CBY23358.1 - 2.7 6.6 8.4 4 6.1 7.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Forkhead PF00250.18 CBY23359.1 - 2.2e-21 75.9 0.6 5.2e-21 74.7 0.6 1.5 1 0 0 1 1 1 1 Forkhead domain Trypsin PF00089.26 CBY23361.1 - 3.4e-48 164.3 0.0 2.3e-47 161.7 0.0 2.2 2 1 0 2 2 2 1 Trypsin CUB PF00431.20 CBY23361.1 - 2.8e-28 98.4 0.5 8.7e-14 51.8 0.1 2.5 2 0 0 2 2 2 2 CUB domain Sulfatase PF00884.23 CBY23362.1 - 2.8e-49 168.2 0.0 1.2e-47 162.8 0.0 2.8 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 CBY23362.1 - 2.1e-05 24.3 0.0 0.047 13.3 0.0 3.3 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CBY23362.1 - 0.00036 19.3 0.0 0.00075 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 CBY23362.1 - 0.0093 16.2 1.7 0.015 15.5 0.3 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4976) Sulfatase PF00884.23 CBY23363.1 - 3.2e-55 187.7 0.4 9.2e-55 186.2 0.4 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY23363.1 - 1.6e-07 31.3 2.9 1.4e-06 28.2 0.7 2.8 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 CBY23363.1 - 4.7e-06 26.8 0.0 1.7e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 CBY23363.1 - 3e-05 22.8 0.0 9.3e-05 21.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 CBY23363.1 - 0.034 14.0 0.1 12 5.9 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function Skp1 PF01466.19 CBY23363.1 - 0.48 10.6 3.4 10 6.3 0.1 2.7 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Sulfotransfer_1 PF00685.27 CBY23365.1 - 2.2e-17 63.4 0.5 2.7e-17 63.1 0.5 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY23365.1 - 0.0035 17.8 0.0 0.0064 16.9 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family SCAB_CC PF16712.5 CBY23365.1 - 0.0074 16.1 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Coiled-coil regions of plant-specific actin-binding protein UCH PF00443.29 CBY23366.1 - 8.4e-20 71.3 0.3 1.1e-19 70.9 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY23366.1 - 8e-07 29.0 2.2 3.2e-06 27.0 2.2 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HLH PF00010.26 CBY23367.1 - 9.1e-08 32.0 0.0 3.1e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain UCH PF00443.29 CBY23368.1 - 2.3e-48 164.9 1.3 2.3e-48 164.9 1.3 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY23368.1 - 4.8e-11 42.8 9.8 4.8e-11 42.8 9.8 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase IFT57 PF10498.9 CBY23370.1 - 0.00051 19.1 21.5 0.00062 18.8 10.7 2.5 2 1 0 2 2 2 2 Intra-flagellar transport protein 57 FUSC PF04632.12 CBY23370.1 - 0.039 12.5 1.4 0.91 8.0 0.0 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family DUF4995 PF16386.5 CBY23370.1 - 0.061 13.3 0.7 0.35 10.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function Fumerase_C PF05683.12 CBY23370.1 - 0.077 12.3 1.4 0.13 11.6 0.1 2.1 2 0 0 2 2 2 0 Fumarase C-terminus CLZ PF16526.5 CBY23370.1 - 0.081 13.3 20.6 0.35 11.3 1.2 5.5 4 4 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 CBY23370.1 - 0.22 11.6 30.1 0.038 14.0 2.9 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) GAS PF13851.6 CBY23370.1 - 0.32 10.3 31.5 2.7 7.3 3.1 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 CBY23370.1 - 0.39 11.4 25.3 1.2 9.8 3.8 5.6 3 2 3 6 6 6 0 SlyX NPV_P10 PF05531.12 CBY23370.1 - 0.41 11.1 29.6 0.81 10.2 0.3 5.7 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 CBY23370.1 - 0.43 8.7 31.2 1 7.5 17.9 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.6 CBY23370.1 - 0.46 10.9 24.5 0.17 12.3 7.3 4.1 3 1 2 5 5 5 0 Snapin/Pallidin ApoO PF09769.9 CBY23370.1 - 1.2 9.1 5.3 1.1 9.2 0.2 3.1 2 2 1 3 3 3 0 Apolipoprotein O DUF4477 PF14780.6 CBY23370.1 - 1.4 8.5 7.6 5.4 6.6 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4477) TSC22 PF01166.18 CBY23370.1 - 1.6 9.1 11.6 8.7 6.7 0.9 3.8 2 2 0 2 2 2 0 TSC-22/dip/bun family Syntaxin_2 PF14523.6 CBY23370.1 - 1.7 9.1 28.2 6.6e+02 0.7 3.8 4.1 1 1 1 2 2 2 0 Syntaxin-like protein Metal_resist PF13801.6 CBY23370.1 - 1.8 8.8 4.8 0.75 10.0 0.2 2.7 3 0 0 3 3 3 0 Heavy-metal resistance Vps51 PF08700.11 CBY23370.1 - 1.8 8.7 23.6 2.5 8.2 1.7 5.4 5 2 1 6 6 6 0 Vps51/Vps67 DUF4349 PF14257.6 CBY23370.1 - 2.3 7.6 19.7 0.015 14.7 5.9 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF16 PF01519.16 CBY23370.1 - 2.5 8.6 32.5 1.6 9.3 4.5 4.8 1 1 2 3 3 2 0 Protein of unknown function DUF16 Fez1 PF06818.15 CBY23370.1 - 3.5 8.0 30.0 4.4 7.7 13.2 3.0 1 1 1 3 3 3 0 Fez1 DUF4407 PF14362.6 CBY23370.1 - 4.5 6.5 28.3 2.8 7.2 13.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PSII_Pbs27 PF13326.6 CBY23370.1 - 4.6 7.5 12.9 3.5 8.0 2.3 2.9 2 1 1 3 3 3 0 Photosystem II Pbs27 Fib_alpha PF08702.10 CBY23370.1 - 7.2 6.8 28.5 0.96 9.6 3.2 4.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 CBY23370.1 - 7.9 6.8 37.7 0.14 12.4 4.4 4.5 1 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF2524 PF10732.9 CBY23370.1 - 8.7 6.7 10.8 0.71 10.2 0.2 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2524) CorA PF01544.18 CBY23370.1 - 8.8 5.5 16.8 7.2 5.8 6.3 2.7 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DSPc PF00782.20 CBY23371.1 - 8.6e-20 70.9 0.1 5.2e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY23371.1 - 0.00016 21.9 0.0 0.00028 21.0 0.0 1.4 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBY23371.1 - 0.0024 17.5 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 CBY23371.1 - 0.092 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF915 PF06028.11 CBY23371.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CDKN3 PF05706.12 CBY23371.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Cyclin_N PF00134.23 CBY23372.1 - 3.1e-19 69.0 0.4 5.3e-19 68.2 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain NPH3 PF03000.14 CBY23372.1 - 0.002 17.8 0.6 0.0034 17.1 0.6 1.4 1 0 0 1 1 1 1 NPH3 family JmjC PF02373.22 CBY23373.1 - 1.1e-13 51.6 2.1 3.7e-13 49.9 0.0 2.9 3 0 0 3 3 3 1 JmjC domain, hydroxylase FYVE_2 PF02318.16 CBY23373.1 - 0.0088 16.3 4.7 0.0088 16.3 4.7 2.6 2 0 0 2 2 2 1 FYVE-type zinc finger TackOD1 PF18551.1 CBY23373.1 - 0.046 13.4 13.6 0.36 10.5 9.9 3.3 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 zf-C5HC2 PF02928.16 CBY23373.1 - 0.51 10.8 11.6 2.1 8.8 11.6 2.1 1 0 0 1 1 1 0 C5HC2 zinc finger DZR PF12773.7 CBY23373.1 - 1.2 9.2 13.9 0.43 10.6 1.8 3.1 2 1 1 3 3 3 0 Double zinc ribbon C1_2 PF03107.16 CBY23373.1 - 4.3 7.7 15.3 0.12 12.7 4.0 3.3 3 0 0 3 3 3 0 C1 domain FYVE PF01363.21 CBY23373.1 - 7.7 6.7 16.6 0.82 9.8 10.9 2.3 2 0 0 2 2 2 0 FYVE zinc finger CDO_I PF05995.12 CBY23374.1 - 6.3e-39 133.0 0.0 7.4e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CBY23374.1 - 1e-05 25.1 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO DUF4750 PF15938.5 CBY23376.1 - 6.7e-08 32.1 0.7 7.6e-08 31.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) Sugar_tr PF00083.24 CBY23377.1 - 4.8e-18 65.3 14.8 2.1e-17 63.2 14.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY23377.1 - 2.7e-09 36.4 16.6 5.7e-09 35.3 16.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CBY23377.1 - 6.4e-05 21.7 0.5 6.4e-05 21.7 0.5 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein Zona_pellucida PF00100.23 CBY23378.1 - 9.3e-43 146.9 5.9 1.1e-42 146.6 5.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF4389 PF14333.6 CBY23378.1 - 0.15 12.0 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DAG1 PF05454.11 CBY23378.1 - 0.29 10.5 1.6 2.8 7.2 0.3 2.3 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PLAC8 PF04749.17 CBY23379.1 - 1.2e-09 39.1 21.1 1.5e-09 38.7 21.1 1.1 1 0 0 1 1 1 1 PLAC8 family Serpin PF00079.20 CBY23380.1 - 1.1e-55 189.5 0.1 1.9e-55 188.7 0.1 1.3 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Neur_chan_LBD PF02931.23 CBY23382.1 - 9.6e-14 51.3 0.2 1.2e-13 51.0 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain YjeF_N PF03853.15 CBY23382.1 - 0.2 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 2OG-FeII_Oxy PF03171.20 CBY23383.1 - 1.8e-15 57.2 0.0 3.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MAM PF00629.23 CBY23384.1 - 2.6e-23 82.7 0.0 4.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Trypsin PF00089.26 CBY23385.1 - 3.5e-32 112.0 0.5 8.1e-32 110.8 0.2 1.8 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 CBY23385.1 - 6.2e-14 52.3 0.3 3.6e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 CUB domain Ammonium_transp PF00909.21 CBY23386.1 - 1e-18 67.2 0.2 4.3e-18 65.2 0.2 1.7 1 1 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 CBY23387.1 - 3.6e-78 263.0 33.0 4.4e-78 262.7 33.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG2 PF06148.11 CBY23388.1 - 0.012 15.7 0.4 0.025 14.7 0.4 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MFS_1 PF07690.16 CBY23389.1 - 8.6e-37 126.9 23.2 8.6e-37 126.9 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY23389.1 - 2.2e-11 43.3 4.9 4.7e-11 42.2 4.9 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 CBY23389.1 - 7.7e-10 37.7 10.4 8.2e-07 27.7 1.0 3.4 2 2 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 CBY23389.1 - 0.0002 20.0 6.5 0.0002 20.0 6.5 3.2 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.13 CBY23389.1 - 0.00069 18.1 1.0 0.00069 18.1 1.0 1.4 2 0 0 2 2 2 1 Transmembrane secretion effector HisKA_4TM PF16926.5 CBY23389.1 - 0.92 9.1 3.4 0.67 9.5 1.3 1.8 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase MFS_1_like PF12832.7 CBY23389.1 - 7.8 5.2 12.2 0.62 8.9 3.4 2.4 2 0 0 2 2 2 0 MFS_1 like family Acid_PPase PF12689.7 CBY23390.1 - 4.6e-34 117.7 2.2 8e-27 94.1 0.1 2.0 1 1 1 2 2 2 2 Acid Phosphatase Cystatin PF00031.21 CBY23392.1 - 5.3e-08 33.0 0.0 5.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain ACPS PF01648.20 CBY23393.1 - 6.6e-10 39.1 0.0 1.8e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Period_C PF12114.8 CBY23395.1 - 0.042 13.4 0.3 0.049 13.2 0.3 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SHMT PF00464.19 CBY23396.1 - 3e-105 352.1 0.0 3.8e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase SHMT PF00464.19 CBY23397.1 - 2.9e-39 134.8 0.0 3.7e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase SET PF00856.28 CBY23398.1 - 3.4e-16 60.1 1.0 1.3e-15 58.1 0.1 2.5 2 1 0 2 2 2 1 SET domain Chromo PF00385.24 CBY23398.1 - 0.00024 21.0 0.3 0.0009 19.1 0.3 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain COG6 PF06419.11 CBY23399.1 - 2.8e-166 554.4 12.7 3.5e-166 554.1 12.7 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Sec34 PF04136.15 CBY23399.1 - 0.0027 17.6 3.7 0.0086 16.0 2.5 2.5 2 0 0 2 2 2 1 Sec34-like family OmpH PF03938.14 CBY23399.1 - 0.061 13.7 4.7 0.099 13.0 3.7 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MCC-bdg_PDZ PF10506.9 CBY23399.1 - 0.068 13.2 1.0 0.34 11.0 1.0 2.2 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Cas_DxTHG PF09455.10 CBY23399.1 - 0.12 12.0 4.5 0.24 10.9 4.5 1.5 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Fmp27_WPPW PF10359.9 CBY23399.1 - 0.13 11.0 4.5 0.2 10.4 4.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4164 PF13747.6 CBY23399.1 - 0.14 12.5 3.0 0.26 11.6 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 CBY23399.1 - 0.15 12.6 3.8 0.46 11.0 3.8 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 CBY23399.1 - 0.18 12.6 4.3 0.64 10.8 1.7 3.0 3 0 0 3 3 3 0 Occludin homology domain DASH_Dad3 PF08656.10 CBY23399.1 - 0.21 11.7 3.1 0.28 11.3 0.6 2.6 2 0 0 2 2 1 0 DASH complex subunit Dad3 Fib_alpha PF08702.10 CBY23399.1 - 0.22 11.7 4.7 0.58 10.3 2.1 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mod_r PF07200.13 CBY23399.1 - 0.48 10.5 11.2 6 7.0 4.1 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 CBY23399.1 - 0.5 10.4 6.9 2.7 8.1 1.8 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) CHASE3 PF05227.13 CBY23399.1 - 1 9.2 6.7 0.24 11.3 1.2 2.6 2 1 1 3 3 3 0 CHASE3 domain SHE3 PF17078.5 CBY23399.1 - 6.8 6.3 11.0 0.096 12.4 0.7 2.8 3 1 0 4 4 4 0 SWI5-dependent HO expression protein 3 Prenyltrans PF00432.21 CBY23400.1 - 2.3e-10 40.0 0.0 3.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat Prenyltrans PF00432.21 CBY23401.1 - 2.8e-25 87.8 5.0 2e-11 43.4 0.0 4.3 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CBY23401.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain PAP_assoc PF03828.19 CBY23402.1 - 1.9e-18 66.4 1.1 4.9e-11 42.7 0.3 2.8 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY23402.1 - 1.4e-10 41.3 0.1 0.00013 22.2 0.0 2.6 2 0 0 2 2 2 2 Nucleotidyltransferase domain zf-CCHC PF00098.23 CBY23402.1 - 2.9e-10 39.8 9.7 4.1e-05 23.5 0.6 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 CBY23402.1 - 5.6e-06 26.1 15.6 0.00066 19.4 6.9 2.6 2 0 0 2 2 2 2 Zinc knuckle Polbeta PF18765.1 CBY23402.1 - 4.6e-05 23.4 0.4 0.14 12.3 0.0 2.8 2 0 0 2 2 2 2 Polymerase beta, Nucleotidyltransferase zf-CCHC_4 PF14392.6 CBY23402.1 - 0.00064 19.4 5.2 0.33 10.7 0.1 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 CBY23402.1 - 5.2 7.0 6.8 2.7 7.9 1.4 2.4 2 0 0 2 2 2 0 Zinc knuckle Na_trans_assoc PF06512.13 CBY23402.1 - 5.8 7.1 17.3 0.42 10.9 2.8 3.0 3 0 0 3 3 3 0 Sodium ion transport-associated COesterase PF00135.28 CBY23403.1 - 1e-103 347.9 0.0 1.3e-103 347.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY23403.1 - 1.7e-06 28.0 0.6 1.3e-05 25.1 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Di19_C PF14571.6 CBY23405.1 - 0.015 15.8 0.2 0.02 15.4 0.2 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal NTP_transf_2 PF01909.23 CBY23405.1 - 0.043 14.1 1.2 0.054 13.8 1.2 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase domain Spore_YhaL PF14147.6 CBY23408.1 - 0.054 13.2 1.3 0.055 13.2 1.3 1.2 1 0 0 1 1 1 0 Sporulation protein YhaL Spo7_2_N PF15407.6 CBY23413.1 - 0.028 14.0 0.1 0.052 13.2 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 TSP_1 PF00090.19 CBY23414.1 - 1.4e-10 41.2 148.5 5.9e-05 23.2 15.4 10.1 9 1 0 9 9 9 8 Thrombospondin type 1 domain TSP_1 PF00090.19 CBY23415.1 - 6.3e-25 87.1 175.5 1e-05 25.6 7.6 11.2 9 2 1 10 10 10 9 Thrombospondin type 1 domain Peptidase_C1 PF00112.23 CBY23416.1 - 3.3e-15 56.8 0.0 3.3e-15 56.8 0.0 2.6 2 1 0 2 2 2 1 Papain family cysteine protease TSP_1 PF00090.19 CBY23416.1 - 0.0031 17.7 19.4 0.0031 17.7 19.4 5.8 4 1 0 4 4 4 2 Thrombospondin type 1 domain zf-H2C2_2 PF13465.6 CBY23417.1 - 5.4e-20 70.9 21.8 1.1e-09 38.2 1.3 4.7 4 1 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY23417.1 - 1.1e-15 57.1 33.2 7.6e-06 26.1 1.7 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY23417.1 - 1.1e-09 38.3 33.8 4.1e-05 24.1 0.9 5.0 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CBY23417.1 - 4.3e-05 24.2 18.2 0.084 13.6 4.8 3.3 2 1 1 3 3 3 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CBY23417.1 - 0.00034 20.5 17.0 0.045 13.8 0.7 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CBY23417.1 - 0.0023 18.0 16.1 1.8 8.8 0.9 4.5 4 0 0 4 4 4 2 Zinc ribbon domain zf_UBZ PF18439.1 CBY23417.1 - 0.007 15.9 12.7 0.3 10.7 2.0 4.3 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 CBY23417.1 - 0.007 16.6 7.4 0.051 13.9 0.5 4.2 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CBY23417.1 - 0.2 11.5 0.1 0.2 11.5 0.1 4.7 5 0 0 5 5 4 0 C2H2-type zinc-finger domain zf-met PF12874.7 CBY23417.1 - 0.44 11.0 27.8 0.49 10.9 0.1 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type XPA_N PF01286.18 CBY23417.1 - 1.1 9.4 12.8 3.6 7.7 0.4 4.1 4 0 0 4 4 4 0 XPA protein N-terminal zinc_ribbon_15 PF17032.5 CBY23417.1 - 2.6 8.9 15.6 1 10.2 3.6 3.0 1 1 2 3 3 3 0 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 CBY23417.1 - 2.7 8.0 11.3 4.8 7.2 2.1 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-C2H2_11 PF16622.5 CBY23417.1 - 3 7.7 23.6 0.66 9.8 0.8 4.3 5 0 0 5 5 5 0 zinc-finger C2H2-type Prok-RING_1 PF14446.6 CBY23417.1 - 3.7 7.5 18.0 7.1 6.6 0.5 4.5 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zf-MYST PF17772.1 CBY23417.1 - 3.8 7.2 14.3 1.6 8.4 0.4 4.2 5 0 0 5 5 5 0 MYST family zinc finger domain zinc_ribbon_9 PF14369.6 CBY23417.1 - 4.2 7.7 5.9 23 5.3 0.0 3.1 4 0 0 4 4 3 0 zinc-ribbon zf-C2HE PF16278.5 CBY23417.1 - 5.6 7.5 20.5 0.84 10.1 1.3 4.0 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 CBY23417.1 - 6.7 6.7 11.7 9.8 6.2 0.1 4.0 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 CBY23417.1 - 9 6.7 19.1 1.2 9.5 3.7 3.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Lectin_C PF00059.21 CBY23418.1 - 3.1e-28 98.6 32.3 4.6e-08 33.8 0.0 6.7 5 2 0 5 5 5 4 Lectin C-type domain Trefoil PF00088.18 CBY23418.1 - 0.00024 20.9 6.3 0.00074 19.3 6.3 1.9 1 0 0 1 1 1 1 Trefoil (P-type) domain DUF3948 PF13134.6 CBY23418.1 - 7.8 6.3 5.1 1.3 8.8 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) FXMRP1_C_core PF12235.8 CBY23420.1 - 0.65 10.6 14.1 0.9 10.2 14.1 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Kelch_6 PF13964.6 CBY23421.1 - 2.1e-05 24.6 3.9 12 6.4 0.0 6.6 7 0 0 7 7 7 1 Kelch motif Kelch_1 PF01344.25 CBY23421.1 - 0.064 12.8 1.7 32 4.2 0.0 4.1 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 CBY23421.1 - 0.32 11.0 5.4 46 4.2 0.0 4.8 5 0 0 5 5 5 0 Kelch motif Kelch_3 PF13415.6 CBY23421.1 - 0.8 10.1 6.6 25 5.3 0.1 4.9 4 1 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY23422.1 - 0.0072 16.6 0.0 7.3 7.0 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Acetyltransf_18 PF18014.1 CBY23423.1 - 3.7e-14 52.6 0.0 8.9e-14 51.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY23423.1 - 1.8e-12 47.5 0.1 9.6e-10 38.7 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY23423.1 - 4e-08 33.2 0.0 6e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY23423.1 - 2.9e-05 24.4 0.0 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CBY23423.1 - 0.016 15.9 0.0 0.038 14.7 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2706 PF10913.8 CBY23423.1 - 0.058 13.2 0.1 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) VEG PF06257.11 CBY23423.1 - 0.11 12.5 0.4 0.23 11.5 0.4 1.4 1 0 0 1 1 1 0 Biofilm formation stimulator VEG FR47 PF08445.10 CBY23423.1 - 0.17 11.9 0.2 0.42 10.6 0.2 1.6 1 1 0 1 1 1 0 FR47-like protein PanZ PF12568.8 CBY23423.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Trypsin PF00089.26 CBY23424.1 - 8.5e-17 61.7 0.1 1.4e-16 61.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin Phlebovirus_NSM PF07246.11 CBY23425.1 - 0.076 12.4 0.2 0.18 11.1 0.1 1.7 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Serglycin PF04360.12 CBY23425.1 - 0.44 10.5 2.4 0.78 9.7 0.6 2.1 2 0 0 2 2 2 0 Serglycin AP_endonuc_2 PF01261.24 CBY23426.1 - 3.9e-20 72.2 0.0 7.9e-20 71.2 0.0 1.4 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel EF-hand_1 PF00036.32 CBY23426.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 CBY23426.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DUF3341 PF11821.8 CBY23427.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) AP_endonuc_2 PF01261.24 CBY23427.1 - 0.063 12.7 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2225 PF09986.9 CBY23427.1 - 0.11 12.2 0.4 0.11 12.2 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) RicinB_lectin_2 PF14200.6 CBY23428.1 - 1.2e-11 45.1 1.1 9.5e-05 23.1 0.5 2.0 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CBY23428.1 - 5.6e-08 33.1 0.0 8.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PepSY_like PF11396.8 CBY23431.1 - 0.13 12.9 1.2 2.2 8.9 0.1 2.8 2 1 0 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like U3_assoc_6 PF08640.11 CBY23432.1 - 0.049 13.7 0.6 0.16 12.1 0.4 2.0 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Trypsin PF00089.26 CBY23433.1 - 9e-63 212.0 0.2 1.2e-62 211.6 0.2 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY23433.1 - 1.5e-05 26.0 0.0 2.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY23433.1 - 0.00055 20.3 0.0 0.0015 18.9 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Sina PF03145.16 CBY23433.1 - 4 7.3 10.1 9 6.2 0.8 2.6 3 0 0 3 3 3 0 Seven in absentia protein family IL8 PF00048.20 CBY23434.1 - 0.0084 16.2 1.3 0.1 12.8 0.1 3.3 4 0 0 4 4 4 1 Small cytokines (intecrine/chemokine), interleukin-8 like RVT_1 PF00078.27 CBY23435.1 - 3.3e-09 36.6 0.0 1e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CBY23435.1 - 0.0045 16.8 0.0 0.019 14.8 0.0 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SIT PF15330.6 CBY23435.1 - 0.98 9.9 4.2 0.47 10.9 0.8 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT 7tm_1 PF00001.21 CBY23437.1 - 1.9e-32 112.7 8.0 1e-31 110.3 8.0 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CBY23437.1 - 0.0023 17.7 6.2 0.0068 16.2 6.2 1.9 1 1 0 1 1 1 1 Olfactory receptor LapA_dom PF06305.11 CBY23437.1 - 0.0024 17.6 0.1 0.0024 17.6 0.1 2.6 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DHHC PF01529.20 CBY23437.1 - 7.6 6.6 16.6 1.1 9.4 2.3 3.3 3 1 0 3 3 3 0 DHHC palmitoyltransferase STOP PF05217.12 CBY23438.1 - 0.024 14.9 0.1 0.024 14.9 0.1 2.3 2 0 0 2 2 2 0 STOP protein EF-hand_1 PF00036.32 CBY23439.1 - 6.1e-08 31.7 1.5 0.00087 18.7 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY23439.1 - 1.6e-06 27.3 1.2 0.0013 18.1 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY23439.1 - 2.3e-06 27.1 3.6 0.048 13.6 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY23439.1 - 3.9e-06 27.2 2.3 0.056 13.9 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 CBY23440.1 - 6.3e-10 39.4 8.4 2e-08 34.6 1.4 2.1 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY23440.1 - 5e-08 32.0 6.6 0.00014 21.2 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY23440.1 - 4.5e-07 29.3 3.8 0.00046 19.9 0.3 3.4 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY23440.1 - 0.021 14.3 1.2 0.84 9.2 0.3 2.7 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 CBY23440.1 - 0.037 13.9 3.7 0.11 12.4 0.2 3.0 1 1 1 2 2 2 0 EF-hand domain pair zf-C3HC4_3 PF13920.6 CBY23441.1 - 0.00089 19.1 12.5 0.0072 16.2 6.8 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY23441.1 - 0.005 16.8 13.8 0.02 14.8 9.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain FlhC PF05280.11 CBY23441.1 - 0.035 13.8 0.5 0.051 13.3 0.5 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Prok-RING_4 PF14447.6 CBY23441.1 - 0.063 13.1 11.5 0.39 10.6 11.5 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY23441.1 - 0.074 12.9 9.5 1.6 8.7 9.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY23441.1 - 0.2 11.5 14.9 1.4 8.8 15.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY23441.1 - 0.49 10.5 10.7 1.1 9.4 10.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 CBY23441.1 - 1 9.3 9.7 2.3 8.1 9.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CBY23441.1 - 2.4 8.6 14.7 17 5.8 15.0 2.1 1 1 1 2 2 2 0 Ring finger domain Acetyltransf_1 PF00583.25 CBY23443.1 - 1.5e-05 25.2 0.0 3.2e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY23443.1 - 2.9e-05 24.4 0.0 0.00022 21.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY23443.1 - 0.0016 18.5 0.0 0.003 17.7 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 CBY23443.1 - 0.0032 17.4 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY23443.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Zona_pellucida PF00100.23 CBY23444.1 - 1.1e-21 77.8 1.3 1.3e-21 77.5 1.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Astacin PF01400.24 CBY23446.1 - 2.6e-11 43.5 0.0 6.3e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY23446.1 - 0.0029 17.8 18.1 0.032 14.4 1.8 3.2 2 1 1 3 3 3 2 Calcium-binding EGF domain Astacin PF01400.24 CBY23447.1 - 1.8e-08 34.2 0.1 4.7e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY23447.1 - 3.8e-07 30.2 7.2 3.8e-07 30.2 7.2 4.1 4 0 0 4 4 4 2 Calcium-binding EGF domain Ldl_recept_a PF00057.18 CBY23447.1 - 0.064 13.5 0.7 0.064 13.5 0.7 4.6 3 1 1 4 4 4 0 Low-density lipoprotein receptor domain class A UPF0054 PF02130.17 CBY23447.1 - 0.09 12.6 0.8 5.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 EGF_3 PF12947.7 CBY23447.1 - 3.8 7.8 34.3 0.087 13.0 5.7 4.2 4 0 0 4 4 4 0 EGF domain OATP PF03137.20 CBY23448.1 - 7.8e-153 509.7 16.9 8.9e-153 509.5 16.9 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CBY23448.1 - 3.6e-18 65.6 18.2 3.6e-18 65.6 18.2 2.5 2 2 0 2 2 2 1 Major Facilitator Superfamily GWT1 PF06423.12 CBY23448.1 - 0.026 14.7 0.6 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 GWT1 Claudin_2 PF13903.6 CBY23449.1 - 5.7e-06 26.2 1.4 7.1e-06 25.9 1.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF5090 PF17009.5 CBY23449.1 - 0.00052 20.0 0.2 0.00068 19.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5090) TssN PF17555.2 CBY23449.1 - 0.12 11.7 1.8 0.2 11.0 1.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2070 PF09843.9 CBY23449.1 - 0.52 8.5 6.7 0.73 8.0 6.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Zona_pellucida PF00100.23 CBY23454.1 - 2.3e-09 37.4 0.1 3.3e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain PEN-2 PF10251.9 CBY23455.1 - 1.3e-05 25.5 0.2 1.9e-05 25.0 0.2 1.2 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase SecG PF03840.14 CBY23455.1 - 0.33 11.0 3.3 2.6 8.2 0.6 2.3 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Oxidored_q2 PF00420.24 CBY23457.1 - 0.032 13.9 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4690 PF15756.5 CBY23457.1 - 0.32 11.6 1.0 0.7 10.5 0.1 1.8 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Tubulin-binding PF00418.19 CBY23458.1 - 2.7e-91 299.2 51.0 2.4e-15 56.2 1.4 8.6 9 0 0 9 9 9 8 Tau and MAP protein, tubulin-binding repeat UXS1_N PF11803.8 CBY23458.1 - 0.0072 16.7 2.0 50 4.4 0.0 5.2 2 2 4 6 6 6 1 UDP-glucuronate decarboxylase N-terminal Ocnus PF05005.15 CBY23458.1 - 0.19 11.8 9.0 0.85 9.8 0.3 4.0 2 2 2 4 4 4 0 Janus/Ocnus family (Ocnus) Phospholip_A2_1 PF00068.19 CBY23459.1 - 3.4e-10 40.4 7.1 3.4e-10 40.4 7.1 2.3 2 1 0 2 2 2 1 Phospholipase A2 Trypsin PF00089.26 CBY23460.1 - 2.7e-17 63.3 0.8 3.7e-12 46.5 0.4 2.5 2 1 0 2 2 2 2 Trypsin MFS_1 PF07690.16 CBY23460.1 - 5.1e-11 42.1 8.3 6.6e-11 41.7 8.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY23460.1 - 0.096 11.5 8.4 0.16 10.8 8.4 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 CBY23462.1 - 3.8e-17 62.3 14.4 5e-17 61.9 14.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY23462.1 - 1.1e-14 54.1 7.0 1.4e-14 53.8 7.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter P5-ATPase PF12409.8 CBY23462.1 - 0.045 13.9 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF3792 PF12670.7 CBY23462.1 - 2.9 8.1 12.7 0.099 12.8 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) BAF250_C PF12031.8 CBY23464.1 - 1.3e-28 100.0 1.9 6.8e-24 84.6 0.3 2.3 2 0 0 2 2 2 2 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 CBY23464.1 - 3.7e-09 37.1 0.0 1e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Carb_anhydrase PF00194.21 CBY23465.1 - 0.0069 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Dicty_spore_N PF04562.12 CBY23466.1 - 0.13 13.0 10.2 11 6.8 0.4 3.2 3 0 0 3 3 3 0 Dictyostelium spore coat protein, N terminus F-box PF00646.33 CBY23467.1 - 0.00016 21.4 0.3 0.00049 19.9 0.2 1.9 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 CBY23467.1 - 0.00016 21.5 0.0 0.0004 20.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like TPR_14 PF13428.6 CBY23467.1 - 0.0016 19.1 0.1 0.02 15.7 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY23467.1 - 0.0079 16.2 0.4 0.0079 16.2 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY23467.1 - 0.024 14.3 0.4 0.059 13.1 0.3 1.7 1 1 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 CBY23467.1 - 0.33 10.9 2.4 0.3 11.0 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RT_RNaseH PF17917.1 CBY23468.1 - 8.5e-32 109.6 0.0 1.5e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY23468.1 - 2.6e-27 94.8 0.0 4.6e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY23468.1 - 1.5e-17 63.9 0.1 3e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box PF00646.33 CBY23469.1 - 0.00016 21.4 0.3 0.00049 19.9 0.2 1.9 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 CBY23469.1 - 0.00016 21.5 0.0 0.0004 20.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like TPR_14 PF13428.6 CBY23469.1 - 0.0016 19.1 0.1 0.02 15.7 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY23469.1 - 0.0079 16.2 0.4 0.0079 16.2 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY23469.1 - 0.024 14.3 0.4 0.059 13.1 0.3 1.7 1 1 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 CBY23469.1 - 0.33 10.9 2.4 0.3 11.0 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_cyclohydroI PF01227.22 CBY23470.1 - 5.6e-77 257.2 0.2 6.3e-77 257.0 0.2 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CBY23470.1 - 0.0096 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein RasGEF PF00617.19 CBY23471.1 - 1.2e-26 94.0 1.4 2.6e-26 92.9 1.4 1.5 1 0 0 1 1 1 1 RasGEF domain Med9 PF07544.13 CBY23471.1 - 0.11 12.6 1.1 0.81 9.8 0.3 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Sulfotransfer_1 PF00685.27 CBY23472.1 - 0.00091 18.8 0.8 0.73 9.3 0.3 2.3 2 1 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY23472.1 - 0.083 13.3 0.0 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Sulfotransferase family TauD PF02668.16 CBY23474.1 - 5.8e-30 105.0 0.0 1.6e-29 103.5 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 CBY23474.1 - 0.00013 21.2 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 CsiD RPE65 PF03055.15 CBY23475.1 - 7.4e-76 256.2 2.1 8.4e-76 256.0 2.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GnRH PF00446.17 CBY23477.1 - 0.0024 18.1 1.4 0.0045 17.2 1.4 1.5 1 0 0 1 1 1 1 Gonadotropin-releasing hormone DUF384 PF04064.13 CBY23478.1 - 0.15 11.9 0.3 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF384) DUF2189 PF09955.9 CBY23479.1 - 4 7.7 7.5 22 5.3 0.4 3.0 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2189) LRR_8 PF13855.6 CBY23481.1 - 4.6e-13 48.7 14.5 2.3e-08 33.7 1.0 3.9 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 CBY23481.1 - 1.8e-05 25.0 13.0 0.0086 16.5 0.3 4.8 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY23481.1 - 0.00044 19.8 6.3 0.004 16.7 3.8 2.7 1 1 1 2 2 2 2 Leucine-rich repeat Erf4 PF10256.9 CBY23481.1 - 1.3 9.2 8.6 0.53 10.4 1.1 2.8 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family YlbE PF14003.6 CBY23481.1 - 1.7 9.2 5.8 0.65 10.5 2.2 2.2 2 0 0 2 2 2 0 YlbE-like protein FSA_C PF10479.9 CBY23481.1 - 2.4 6.2 34.0 0.23 9.6 5.4 2.6 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus LRR_1 PF00560.33 CBY23481.1 - 7 7.6 5.5 3.5e+02 2.5 0.5 4.8 3 1 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.25 CBY23482.1 - 1.9e-11 43.9 0.0 1.9e-11 43.9 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23482.1 - 1.1e-08 34.7 0.0 2.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Porphyrn_cat_1 PF18206.1 CBY23482.1 - 0.048 14.3 0.3 0.11 13.1 0.3 1.6 1 0 0 1 1 1 0 Porphyranase catalytic subdomain 1 YbbR PF07949.12 CBY23484.1 - 0.045 14.1 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 YbbR-like protein ANAPC10 PF03256.16 CBY23485.1 - 0.019 14.6 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) VIT PF08487.10 CBY23486.1 - 1.1e-10 41.7 0.0 3.6e-10 40.0 0.0 2.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Wzt_C PF14524.6 CBY23486.1 - 0.0055 16.7 0.3 11 6.1 0.0 3.8 4 0 0 4 4 4 1 Wzt C-terminal domain A2M PF00207.22 CBY23486.1 - 0.0072 16.2 0.3 1.2 9.0 0.1 3.7 4 0 0 4 4 4 1 Alpha-2-macroglobulin family Transglut_N PF00868.20 CBY23486.1 - 0.026 14.8 2.8 0.043 14.2 0.1 2.8 3 1 1 4 4 4 0 Transglutaminase family VWA_3 PF13768.6 CBY23487.1 - 3.6e-12 46.5 0.1 6.5e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CBY23487.1 - 3.6e-08 33.8 0.1 7.3e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY23487.1 - 0.00063 20.4 0.2 0.003 18.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain TED PF08341.11 CBY23487.1 - 0.047 14.1 0.1 3 8.3 0.0 2.5 2 0 0 2 2 2 0 Thioester domain p450 PF00067.22 CBY23488.1 - 8.8e-56 189.6 0.4 1.1e-55 189.2 0.4 1.1 1 0 0 1 1 1 1 Cytochrome P450 PGM1_C PF18105.1 CBY23488.1 - 0.22 11.0 0.0 0.47 10.0 0.0 1.5 1 0 0 1 1 1 0 PGM1 C-terminal domain IGFBP PF00219.18 CBY23490.1 - 0.028 15.1 2.0 0.057 14.1 2.0 1.5 1 0 0 1 1 1 0 Insulin-like growth factor binding protein B56 PF01603.20 CBY23491.1 - 1.2e-196 653.6 5.6 1.4e-196 653.4 5.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CBY23491.1 - 0.0053 16.7 2.4 1.5 8.7 0.1 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal EMC3_TMCO1 PF01956.16 CBY23491.1 - 1.5 8.6 4.0 0.48 10.1 0.8 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like ETRAMP PF09716.10 CBY23492.1 - 0.092 12.8 1.1 0.16 12.0 0.7 1.7 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) zf-C4 PF00105.18 CBY23493.1 - 3.2e-20 72.4 13.3 6e-20 71.5 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RING_UBOX PF13445.6 CBY23494.1 - 5.4e-07 29.5 3.7 5.4e-07 29.5 3.7 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY23494.1 - 4.6e-06 26.5 10.7 4.6e-06 26.5 10.7 2.5 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY23494.1 - 1.4e-05 24.8 2.5 1.4e-05 24.8 2.5 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY23494.1 - 0.00014 21.7 11.3 0.00014 21.7 11.3 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DUF4533 PF15047.6 CBY23494.1 - 0.00058 19.5 2.5 0.075 12.6 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4533) zf-C3HC4_3 PF13920.6 CBY23494.1 - 0.0013 18.5 16.2 0.0013 18.5 16.2 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 CBY23494.1 - 0.0016 18.5 10.9 0.0016 18.5 10.9 3.6 4 0 0 4 4 4 1 B-box zinc finger DNA_topoisoIV PF00521.20 CBY23494.1 - 0.0018 17.2 0.9 0.0027 16.6 0.9 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A zf-C3HC4_4 PF15227.6 CBY23494.1 - 0.0032 17.6 7.0 0.0032 17.6 7.0 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBY23494.1 - 0.038 14.3 13.1 0.038 14.3 13.1 2.8 2 1 0 2 2 1 0 Ring finger domain zf-RING_6 PF14835.6 CBY23494.1 - 0.042 13.7 0.6 0.042 13.7 0.6 2.6 2 1 1 3 3 3 0 zf-RING of BARD1-type protein RSS_P20 PF11757.8 CBY23494.1 - 1.2 9.6 8.2 3.6 8.1 2.9 2.9 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DUF1043 PF06295.12 CBY23494.1 - 1.8 8.6 6.3 1.1 9.3 3.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) EGF_3 PF12947.7 CBY23496.1 - 1.4e-11 44.4 33.6 8.1e-07 29.1 11.6 4.0 3 0 0 3 3 3 2 EGF domain EGF_CA PF07645.15 CBY23496.1 - 5e-08 33.0 6.5 5e-08 33.0 6.5 5.0 4 0 0 4 4 4 2 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 CBY23496.1 - 8.4e-07 28.9 29.0 0.00045 20.2 7.7 3.8 3 1 1 4 4 4 2 MSP1 EGF domain 1 hEGF PF12661.7 CBY23496.1 - 1.8e-06 28.4 17.3 0.00013 22.4 2.4 4.9 3 0 0 3 3 3 2 Human growth factor-like EGF EGF PF00008.27 CBY23496.1 - 5.9e-05 23.3 25.6 0.013 15.8 6.6 4.1 3 0 0 3 3 3 2 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY23496.1 - 0.00014 22.1 5.8 0.00014 22.1 5.8 4.9 5 0 0 5 5 5 1 Pvs28 EGF domain cEGF PF12662.7 CBY23496.1 - 0.16 11.9 11.5 0.21 11.5 2.6 4.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like Astacin PF01400.24 CBY23497.1 - 4.8e-24 85.0 0.0 1.2e-23 83.7 0.0 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_3 PF12947.7 CBY23497.1 - 4.3e-12 46.0 28.2 9.6e-06 25.7 12.4 3.7 2 0 0 2 2 2 2 EGF domain EGF_CA PF07645.15 CBY23497.1 - 1.5e-08 34.7 27.4 7.3e-08 32.5 6.5 3.7 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 CBY23497.1 - 8.5e-08 32.1 21.7 0.00081 19.4 5.7 3.3 2 0 0 2 2 2 2 MSP1 EGF domain 1 hEGF PF12661.7 CBY23497.1 - 9.4e-05 22.9 23.3 0.00019 21.9 2.4 4.8 4 0 0 4 4 4 2 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 CBY23497.1 - 0.00019 21.6 5.8 0.00019 21.6 5.8 4.3 4 0 0 4 4 4 1 Pvs28 EGF domain EGF PF00008.27 CBY23497.1 - 0.00025 21.3 26.5 0.024 14.9 7.4 3.8 3 0 0 3 3 3 2 EGF-like domain cEGF PF12662.7 CBY23497.1 - 0.55 10.2 13.2 0.3 11.0 2.6 3.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like CBP_BcsG PF11658.8 CBY23499.1 - 0.16 10.3 0.0 0.29 9.5 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG PLAC8 PF04749.17 CBY23501.1 - 1.3e-16 61.4 3.9 1.5e-16 61.2 3.9 1.1 1 0 0 1 1 1 1 PLAC8 family Sulfotransfer_1 PF00685.27 CBY23503.1 - 4.9e-15 55.7 2.9 1.6e-14 54.0 0.4 2.5 1 1 1 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY23503.1 - 3.5e-10 40.6 0.0 2.9e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family DUF2681 PF10883.8 CBY23503.1 - 0.044 14.2 1.0 0.13 12.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Phospholip_A2_1 PF00068.19 CBY23504.1 - 2.8e-28 98.6 15.1 2.8e-28 98.6 15.1 2.2 2 0 0 2 2 2 1 Phospholipase A2 TIG PF01833.24 CBY23505.1 - 1.4e-55 185.3 82.7 5.5e-13 48.8 4.1 13.4 13 1 1 14 14 14 9 IPT/TIG domain G8 PF10162.9 CBY23505.1 - 3.3e-39 133.8 0.0 2.3e-27 95.5 0.0 2.9 2 0 0 2 2 2 2 G8 domain Mucin2_WxxW PF13330.6 CBY23505.1 - 8.3e-10 39.4 2.2 8.3e-10 39.4 2.2 3.1 2 0 0 2 2 2 1 Mucin-2 protein WxxW repeating region Kringle PF00051.18 CBY23505.1 - 1.6e-06 28.4 16.0 1.9e-05 24.9 4.0 3.5 2 1 1 3 3 3 2 Kringle domain PAN_4 PF14295.6 CBY23505.1 - 0.00023 21.0 1.3 0.00023 21.0 1.3 2.6 2 0 0 2 2 2 1 PAN domain GLEYA PF10528.9 CBY23505.1 - 0.00087 19.7 0.4 0.0076 16.6 0.1 3.0 2 0 0 2 2 2 1 GLEYA domain EGF_3 PF12947.7 CBY23505.1 - 0.18 12.1 19.9 0.0099 16.1 5.5 3.6 2 0 0 2 2 2 0 EGF domain PAN_3 PF08277.12 CBY23505.1 - 0.55 10.1 7.1 0.033 14.0 0.9 2.3 2 0 0 2 2 2 0 PAN-like domain LRR_8 PF13855.6 CBY23506.1 - 2e-13 49.9 6.4 2.7e-09 36.6 1.2 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBY23506.1 - 8e-11 42.0 6.2 4.7e-06 26.8 0.6 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY23506.1 - 1.6e-06 27.9 5.7 1.3 9.9 0.0 4.4 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 CBY23506.1 - 0.0015 18.4 3.2 6.5 7.1 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat Pyr_redox_dim PF02852.22 CBY23507.1 - 1.9e-42 144.0 0.3 2.1e-42 143.8 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Arylesterase PF01731.20 CBY23509.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 Arylesterase RNase_H2-Ydr279 PF09468.10 CBY23510.1 - 0.71 10.0 4.1 1.8 8.7 3.7 1.8 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Ephrin_rec_like PF07699.13 CBY23510.1 - 0.76 9.6 12.4 0.06 13.1 2.1 2.9 2 0 0 2 2 2 0 Putative ephrin-receptor like VWA PF00092.28 CBY23511.1 - 2.9e-24 86.3 1.3 5.2e-24 85.4 1.3 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY23511.1 - 6.7e-14 52.4 0.1 1.4e-13 51.4 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY23511.1 - 4.2e-08 33.3 0.0 7.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain SKA1 PF07160.12 CBY23511.1 - 0.078 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF1194 PF06707.11 CBY23511.1 - 0.17 11.1 0.5 0.57 9.3 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1194) TIMELESS PF04821.14 CBY23512.1 - 1.8e-05 24.1 0.4 6.6e-05 22.3 0.1 2.1 2 0 0 2 2 2 1 Timeless protein Fis1_TPR_N PF14852.6 CBY23512.1 - 0.034 13.8 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat WbqC PF08889.11 CBY23512.1 - 0.088 12.7 0.8 0.45 10.4 0.0 2.4 3 0 0 3 3 3 0 WbqC-like protein family LRR_8 PF13855.6 CBY23514.1 - 6.1e-11 41.9 6.6 8.4e-11 41.5 4.6 2.1 2 1 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 CBY23514.1 - 0.00074 19.1 0.2 0.0012 18.4 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRRCT PF01463.24 CBY23514.1 - 0.0027 18.1 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_4 PF12799.7 CBY23514.1 - 0.0032 17.8 13.1 0.017 15.6 2.2 2.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY23514.1 - 0.018 15.0 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBY23514.1 - 0.7 10.7 5.6 12 6.9 0.1 3.3 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 CBY23515.1 - 7.4e-31 105.7 27.0 2e-13 49.9 0.1 5.1 1 1 2 4 4 4 3 Leucine rich repeat LRR_5 PF13306.6 CBY23515.1 - 2.2e-16 60.0 3.8 2.2e-16 60.0 3.8 2.4 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY23515.1 - 6.6e-16 58.2 25.3 4.3e-06 27.0 2.1 5.5 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY23515.1 - 2.2e-10 40.3 11.2 3e-06 26.8 2.7 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CBY23515.1 - 1.6e-07 30.8 13.8 0.47 10.6 0.4 6.7 5 1 1 6 6 6 3 Leucine Rich repeat LRRNT PF01462.18 CBY23515.1 - 3.8e-05 23.2 2.2 7.7e-05 22.2 2.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 CBY23515.1 - 0.00061 20.0 28.7 0.44 11.3 0.1 8.0 8 2 0 8 8 8 2 Leucine Rich Repeat p450 PF00067.22 CBY23516.1 - 5e-39 134.3 0.0 1.8e-35 122.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Bax1-I PF01027.20 CBY23517.1 - 7.3e-38 130.5 16.5 8.5e-38 130.3 16.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CBY23517.1 - 0.45 10.0 9.7 0.69 9.4 9.7 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF2244 PF10003.9 CBY23517.1 - 3.7 7.2 6.2 0.58 9.8 0.1 2.4 1 1 0 2 2 2 0 Integral membrane protein (DUF2244) Condensation PF00668.20 CBY23520.1 - 4.3e-05 22.4 0.1 0.00014 20.7 0.1 1.7 1 1 0 1 1 1 1 Condensation domain RT_RNaseH_2 PF17919.1 CBY23521.1 - 1.9e-23 82.3 0.0 5.6e-23 80.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY23521.1 - 2.2e-17 63.3 0.4 1.6e-16 60.5 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CBY23521.1 - 1.1e-16 61.0 0.0 4e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY23521.1 - 4.6e-11 43.0 0.0 1.6e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY23521.1 - 1.9e-08 34.3 0.1 1.9e-08 34.3 0.1 2.7 3 0 0 3 3 2 1 Integrase zinc binding domain SAP PF02037.27 CBY23521.1 - 9.2e-07 28.5 3.0 1e-06 28.3 0.3 2.6 3 0 0 3 3 3 1 SAP domain Asp_protease_2 PF13650.6 CBY23521.1 - 1.7e-06 28.6 0.2 4.5e-06 27.2 0.2 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CBY23521.1 - 1.3e-05 25.0 2.3 3.8e-05 23.5 2.3 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 CBY23521.1 - 3e-05 24.1 1.2 0.0036 17.5 0.3 4.0 4 0 0 4 4 4 1 H2C2 zinc finger gag-asp_proteas PF13975.6 CBY23521.1 - 6.9e-05 23.3 0.1 0.00019 21.9 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 CBY23521.1 - 0.0044 16.8 4.2 0.013 15.3 4.2 1.8 1 0 0 1 1 1 1 Zinc knuckle AMP-binding PF00501.28 CBY23523.1 - 1.7e-62 211.4 0.0 2e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CBY23523.1 - 1.6e-16 60.0 3.5 8.1e-16 57.7 2.9 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Ank_4 PF13637.6 CBY23524.1 - 1.3e-23 83.0 2.8 2.1e-09 37.7 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY23524.1 - 5.7e-23 81.3 1.8 2.1e-10 41.0 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY23524.1 - 1.3e-19 69.9 3.3 2.1e-07 31.1 0.2 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY23524.1 - 2.2e-18 64.4 4.8 0.00039 20.7 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CBY23524.1 - 6.8e-15 54.7 4.2 2.7e-06 27.6 0.0 5.0 6 0 0 6 6 6 3 Ankyrin repeat Muraidase PF11860.8 CBY23524.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramidase DUF228 PF02989.14 CBY23524.1 - 0.13 12.0 1.5 0.23 11.3 1.5 1.3 1 0 0 1 1 1 0 Lyme disease proteins of unknown function Ras PF00071.22 CBY23525.1 - 5.3e-40 136.7 0.1 6.2e-40 136.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY23525.1 - 2.2e-27 95.6 0.1 3.6e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY23525.1 - 7.3e-12 45.1 0.1 9.2e-12 44.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY23525.1 - 1.8e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY23525.1 - 1.5e-06 28.3 0.0 3.6e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CBY23525.1 - 9.7e-05 22.3 0.2 0.06 13.1 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CBY23525.1 - 0.00015 21.4 0.5 0.0049 16.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY23525.1 - 0.00071 19.5 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CBY23525.1 - 0.00098 19.1 0.1 0.0018 18.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 CBY23525.1 - 0.0063 16.0 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 CBY23525.1 - 0.0087 15.7 0.5 3.4 7.2 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 CBY23525.1 - 0.016 14.4 0.0 0.038 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CBY23525.1 - 0.026 14.3 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CBY23525.1 - 0.028 13.9 0.1 0.057 12.9 0.1 1.7 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 CBY23525.1 - 0.051 13.9 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ISP3_C PF18045.1 CBY23525.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 ISP3 C-terminal AAA_16 PF13191.6 CBY23525.1 - 0.063 13.7 0.2 0.079 13.3 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CBY23525.1 - 0.085 12.6 0.1 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.18 CBY23525.1 - 0.13 11.5 0.4 8.8 5.5 0.0 2.1 2 0 0 2 2 2 0 Septin ATPase_2 PF01637.18 CBY23525.1 - 0.16 11.8 2.3 3.9 7.3 0.1 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea adh_short_C2 PF13561.6 CBY23526.1 - 7.1e-10 38.8 0.0 8.6e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY23526.1 - 3.3e-09 36.5 0.0 4.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Cadherin_C_2 PF16492.5 CBY23527.1 - 0.015 16.1 0.0 0.047 14.4 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Orf78 PF06024.12 CBY23527.1 - 0.079 13.3 1.0 0.28 11.5 1.0 1.9 1 0 0 1 1 1 0 Orf78 (ac78) Corona_S2 PF01601.16 CBY23527.1 - 8.9 4.7 13.6 13 4.1 13.6 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein C2-set_2 PF08205.12 CBY23528.1 - 1.7e-07 31.2 0.3 1.4e-05 25.0 0.1 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 CBY23528.1 - 7.4e-07 29.4 0.5 0.084 13.2 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 CBY23528.1 - 0.001 19.6 0.5 0.7 10.5 0.1 3.3 2 1 1 3 3 3 1 Immunoglobulin domain Big_7 PF17957.1 CBY23528.1 - 0.0097 16.6 0.8 0.72 10.7 0.0 3.4 2 2 1 3 3 3 1 Bacterial Ig domain Cadherin_C_2 PF16492.5 CBY23528.1 - 0.01 16.6 0.0 0.027 15.2 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Glt_symporter PF03616.14 CBY23528.1 - 0.058 12.1 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter ig PF00047.25 CBY23528.1 - 0.31 11.3 4.0 2.4 8.4 0.1 3.4 4 1 0 4 4 4 0 Immunoglobulin domain PHD_2 PF13831.6 CBY23530.1 - 0.052 13.1 5.1 2.4 7.8 5.2 2.5 1 1 0 1 1 1 0 PHD-finger RRM_1 PF00076.22 CBY23531.1 - 5.5e-21 74.2 0.0 8e-21 73.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY23531.1 - 0.0013 18.5 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBY23531.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY23531.1 - 0.062 13.4 0.0 0.062 13.4 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif RR_TM4-6 PF06459.12 CBY23531.1 - 1.1 9.0 3.5 1.3 8.7 3.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ceramidase_alk PF04734.13 CBY23534.1 - 1.4e-141 472.6 0.0 1.8e-141 472.3 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 CBY23534.1 - 1e-07 32.0 0.0 0.0015 18.5 0.0 2.3 2 0 0 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase, C-terminal LRR_8 PF13855.6 CBY23535.1 - 3e-25 87.8 22.6 8.9e-11 41.4 3.4 4.7 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CBY23535.1 - 2.8e-09 37.1 33.8 2.3e-06 27.8 1.9 6.0 3 2 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY23535.1 - 7.2e-08 32.4 5.8 1.4e-06 28.2 3.0 2.9 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBY23535.1 - 2e-07 30.6 28.3 0.11 13.1 0.8 8.6 8 1 0 8 8 8 4 Leucine Rich Repeat LRR_9 PF14580.6 CBY23535.1 - 0.0027 17.3 7.9 0.011 15.2 0.9 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CBY23535.1 - 0.021 14.8 21.5 8.9 6.7 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich repeat TILa PF12714.7 CBY23535.1 - 0.31 11.0 4.2 0.53 10.3 4.2 1.3 1 0 0 1 1 1 0 TILa domain DUF2236 PF09995.9 CBY23539.1 - 2.3e-14 54.1 0.0 2.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Lipase_3 PF01764.25 CBY23541.1 - 1.1e-19 70.7 0.0 3.9e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 CBY23541.1 - 0.00077 19.1 0.0 0.0041 16.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CBY23541.1 - 0.011 16.3 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CBY23541.1 - 0.096 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein CDC45 PF02724.14 CBY23541.1 - 1.8 6.8 13.0 6.7 4.9 12.8 1.8 2 0 0 2 2 2 0 CDC45-like protein Transformer PF06495.11 CBY23541.1 - 2.6 8.1 28.8 6.7 6.8 28.8 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein DUF1509 PF07420.11 CBY23541.1 - 6.6 5.6 17.3 12 4.8 17.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) cNMP_binding PF00027.29 CBY23542.1 - 5.5e-11 42.4 0.0 9.9e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.10 CBY23542.1 - 0.084 12.5 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Ion transport protein N-terminal ApoC-I PF04691.12 CBY23543.1 - 0.0085 16.0 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Apolipoprotein C-I (ApoC-1) Fumarate_red_D PF02313.17 CBY23544.1 - 0.037 14.1 0.2 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Fumarate reductase subunit D MerE PF05052.12 CBY23544.1 - 3 7.9 7.6 0.16 11.9 0.9 2.1 2 1 1 3 3 3 0 MerE protein CHGN PF05679.16 CBY23545.1 - 2.6e-09 36.4 0.9 1.3e-08 34.1 0.2 2.2 1 1 1 2 2 2 1 Chondroitin N-acetylgalactosaminyltransferase SDP_N PF12278.8 CBY23546.1 - 0.03 14.4 10.3 0.032 14.3 10.3 1.0 1 0 0 1 1 1 0 Sex determination protein N terminal Ku_C PF03730.14 CBY23546.1 - 9.5 7.0 11.5 13 6.6 11.5 1.2 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm O-FucT PF10250.9 CBY23547.1 - 1.9e-05 24.6 0.0 3.2e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ELFV_dehydrog_N PF02812.18 CBY23548.1 - 3e-56 188.8 0.0 5.2e-56 188.1 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 CBY23548.1 - 5.3e-43 147.5 0.1 3e-41 141.8 0.1 2.3 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CENP-F_N PF10481.9 CBY23548.1 - 0.077 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain F5_F8_type_C PF00754.25 CBY23550.1 - 6e-06 26.4 0.1 0.00019 21.6 0.1 2.1 1 1 0 1 1 1 1 F5/8 type C domain SEA PF01390.20 CBY23551.1 - 7.5e-05 22.8 5.1 0.027 14.5 0.1 3.8 2 1 1 3 3 3 2 SEA domain Pox_polyA_pol_N PF12630.7 CBY23551.1 - 0.77 10.1 6.1 1.2 9.5 0.7 2.9 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Myosin_head PF00063.21 CBY23552.1 - 7.5e-269 893.6 0.1 7.5e-269 893.6 0.1 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY23552.1 - 6.6e-151 504.4 256.3 8.5e-151 504.0 256.3 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY23552.1 - 0.0096 15.7 1.3 0.034 14.0 1.3 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 CBY23552.1 - 0.12 12.3 0.2 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF4250 PF14056.6 CBY23552.1 - 1.4 8.9 16.2 0.044 13.7 0.3 5.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) Homeodomain PF00046.29 CBY23553.1 - 4.5e-25 87.3 2.2 4.5e-25 87.3 2.2 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY23553.1 - 0.00055 19.8 0.4 0.0031 17.4 0.0 2.2 2 0 0 2 2 2 1 Homeobox KN domain MRP-L20 PF12824.7 CBY23553.1 - 0.00072 19.8 2.1 0.0013 19.0 2.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DpnI_C PF17726.1 CBY23553.1 - 0.16 12.1 0.7 0.72 10.0 0.1 2.1 2 0 0 2 2 2 0 Dam-replacing HTH domain Kelch_1 PF01344.25 CBY23554.1 - 2e-10 40.1 0.1 5.6e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBY23554.1 - 2.2e-09 37.2 1.2 3.9e-07 30.1 0.1 2.1 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CBY23554.1 - 5.1e-08 32.6 0.5 0.0023 17.8 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY23554.1 - 2e-05 24.5 1.0 0.002 18.1 0.2 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY23554.1 - 0.0015 18.5 0.5 0.39 10.8 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 CBY23554.1 - 0.025 14.9 0.4 0.049 13.9 0.0 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Thyroglobulin_1 PF00086.18 CBY23555.1 - 1.4e-07 31.1 2.3 3.9e-07 29.6 2.3 1.9 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat PAN_1 PF00024.26 CBY23555.1 - 1.3e-06 28.3 2.0 1.3e-06 28.3 2.0 2.3 2 0 0 2 2 2 1 PAN domain DUF4238 PF14022.6 CBY23557.1 - 0.0098 15.4 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) ExsD PF16806.5 CBY23557.1 - 0.13 12.2 0.6 0.22 11.4 0.6 1.3 1 0 0 1 1 1 0 Antiactivator protein ExsD Death PF00531.22 CBY23558.1 - 0.031 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Death domain RVT_1 PF00078.27 CBY23560.1 - 3.6e-23 82.2 0.1 1.1e-22 80.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CBY23560.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family NUC130_3NT PF08158.12 CBY23560.1 - 0.088 13.1 0.2 4.9 7.6 0.1 3.1 2 0 0 2 2 2 0 NUC130/3NT domain PEP-utilisers_N PF05524.13 CBY23561.1 - 0.53 10.5 4.2 64 3.7 0.9 3.5 3 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal TMEM214 PF10151.9 CBY23561.1 - 0.82 8.1 9.7 1.2 7.5 9.7 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator CHIP_TPR_N PF18391.1 CBY23561.1 - 6.6 7.6 8.6 2.5 9.0 3.1 3.0 2 1 1 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain WD40 PF00400.32 CBY23562.1 - 3e-19 69.0 13.6 2.1e-05 25.2 0.0 8.0 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY23562.1 - 5.9e-11 42.5 2.4 0.14 12.5 0.0 5.4 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain EIAV_GP90 PF00971.18 CBY23562.1 - 0.092 11.4 0.1 0.21 10.2 0.1 1.5 1 0 0 1 1 1 0 EIAV coat protein, gp90 Bromodomain PF00439.25 CBY23563.1 - 5.4e-08 32.8 0.6 1.4e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 Bromodomain CUB PF00431.20 CBY23564.1 - 3.5e-14 53.1 0.0 5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain PQQ_2 PF13360.6 CBY23566.1 - 0.051 13.2 0.0 9.3 5.7 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain Beta_propel PF09826.9 CBY23566.1 - 0.098 11.5 0.1 0.59 8.9 0.1 1.8 1 1 1 2 2 2 0 Beta propeller domain WD40 PF00400.32 CBY23566.1 - 0.16 12.9 2.3 1.3 10.1 0.2 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat OSTbeta PF15048.6 CBY23567.1 - 0.033 14.3 2.2 0.046 13.8 2.2 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4366 PF14283.6 CBY23567.1 - 1.8 8.6 8.8 2.3 8.3 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PAF PF15715.5 CBY23567.1 - 7.5 7.1 13.0 2.6 8.6 0.1 2.2 2 0 0 2 2 2 0 PCNA-associated factor histone like domain WH2 PF02205.20 CBY23568.1 - 1.5e-05 24.7 1.1 0.0074 16.1 0.0 3.9 3 0 0 3 3 3 2 WH2 motif bZIP_1 PF00170.21 CBY23570.1 - 0.021 14.9 0.4 0.021 14.9 0.4 1.8 2 0 0 2 2 2 0 bZIP transcription factor 7tm_1 PF00001.21 CBY23571.1 - 2.1e-21 76.4 14.6 8.6e-18 64.6 9.1 2.7 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CBY23571.1 - 2e-05 24.0 6.8 2e-05 24.0 6.8 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.13 CBY23571.1 - 0.0071 15.5 0.8 0.0071 15.5 0.8 1.7 2 0 0 2 2 2 1 Taste receptor protein (TAS2R) DUF2818 PF10993.8 CBY23571.1 - 0.1 13.2 1.7 0.4 11.3 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2818) TatC PF00902.18 CBY23571.1 - 0.2 11.5 1.9 3.6 7.4 0.0 2.8 3 0 0 3 3 3 0 Sec-independent protein translocase protein (TatC) Baculo_11_kDa PF06143.11 CBY23571.1 - 1.9 8.1 4.9 2.5 7.7 0.2 2.8 3 0 0 3 3 3 0 Baculovirus 11 kDa family zf-LITAF-like PF10601.9 CBY23571.1 - 2 8.7 13.5 12 6.2 0.0 3.6 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain APH PF01636.23 CBY23572.1 - 1.3e-18 67.8 0.0 2.5e-18 66.9 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY23572.1 - 8.2e-05 22.3 0.0 0.00024 20.7 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 CBY23572.1 - 0.021 13.7 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 CBY23572.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Kelch_6 PF13964.6 CBY23573.1 - 0.00025 21.2 4.7 0.15 12.4 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CBY23573.1 - 0.00035 20.1 0.3 0.41 10.3 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY23573.1 - 0.00059 19.8 0.3 4.4 7.4 0.0 4.0 3 0 0 3 3 3 1 Galactose oxidase, central domain RhoGEF PF00621.20 CBY23574.1 - 2.7e-29 102.7 0.8 1.5e-17 64.4 0.2 2.2 2 0 0 2 2 2 2 RhoGEF domain Tam41_Mmp37 PF09139.11 CBY23574.1 - 0.0066 15.9 0.1 0.023 14.2 0.0 1.6 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial zf-LITAF-like PF10601.9 CBY23575.1 - 2.4e-15 56.5 19.8 3.2e-15 56.1 19.8 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Phage_integr_3 PF16795.5 CBY23576.1 - 0.0014 18.5 0.5 0.0021 18.0 0.5 1.2 1 0 0 1 1 1 1 Archaeal phage integrase Glyco_hydro_130 PF04041.13 CBY23578.1 - 0.015 14.3 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 beta-1,4-mannooligosaccharide phosphorylase DUF4897 PF16238.5 CBY23578.1 - 0.06 13.2 0.2 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) Ammonium_transp PF00909.21 CBY23579.1 - 2.9e-95 319.3 25.4 3.6e-95 319.0 25.4 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family An_peroxidase PF03098.15 CBY23580.1 - 8.1e-59 199.6 0.0 1.1e-58 199.2 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase FA_hydroxylase PF04116.13 CBY23581.1 - 1.9e-18 67.1 3.8 1.9e-18 67.1 3.8 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily RRM_1 PF00076.22 CBY23582.1 - 1.5e-17 63.1 0.1 2.2e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1797 PF08796.10 CBY23582.1 - 0.1 12.7 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) OB_RNB PF08206.11 CBY23582.1 - 0.14 11.8 3.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain EGF_CA PF07645.15 CBY23583.1 - 1.3e-191 620.6 613.2 3.2e-09 36.9 11.0 41.5 39 3 2 41 41 41 31 Calcium-binding EGF domain EGF_3 PF12947.7 CBY23583.1 - 6.4e-81 266.2 546.6 2.6e-09 37.1 7.6 42.5 40 5 3 43 43 43 30 EGF domain cEGF PF12662.7 CBY23583.1 - 4e-69 228.1 405.7 4.6e-05 23.2 3.0 40.3 39 2 0 39 39 39 30 Complement Clr-like EGF-like EGF PF00008.27 CBY23583.1 - 2.3e-23 82.1 489.2 0.00041 20.6 6.1 40.3 38 1 0 38 38 38 25 EGF-like domain hEGF PF12661.7 CBY23583.1 - 2.8e-20 72.2 438.1 0.0069 17.0 3.6 41.7 40 2 0 40 40 40 25 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY23583.1 - 7.7e-12 45.3 511.5 0.0029 17.8 1.0 40.4 28 7 10 39 39 39 21 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY23583.1 - 0.0035 17.3 22.0 0.0039 17.2 11.0 35.7 34 2 1 35 35 35 16 MSP1 EGF domain 1 RANK_CRD_2 PF18278.1 CBY23583.1 - 0.0077 16.4 1.0 0.0077 16.4 1.0 16.8 21 0 0 21 21 21 2 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Glyco_transf_8 PF01501.20 CBY23584.1 - 3.7e-09 36.5 0.1 7.2e-09 35.6 0.1 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CBY23584.1 - 0.038 13.4 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Gla PF00594.20 CBY23586.1 - 5.2e-11 42.6 3.9 1e-10 41.6 3.9 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF4550 PF15084.6 CBY23586.1 - 0.05 14.0 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) SesA PF17107.5 CBY23586.1 - 0.099 12.8 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Taxilin PF09728.9 CBY23587.1 - 8.7e-74 248.5 51.9 1.4e-73 247.8 51.9 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF3584 PF12128.8 CBY23587.1 - 5.6 4.3 51.6 0.17 9.3 32.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Mce4_CUP1 PF11887.8 CBY23587.1 - 5.9 6.3 9.8 2 7.8 1.1 3.3 2 2 2 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative UCH PF00443.29 CBY23588.1 - 9e-72 241.7 0.5 1.9e-71 240.6 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CBY23588.1 - 2.2e-12 47.4 3.0 2.2e-12 47.4 3.0 3.0 2 2 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 CBY23588.1 - 1e-10 41.7 1.7 6.3e-05 22.7 0.0 3.4 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 CBY23588.1 - 0.00055 19.9 0.1 0.0017 18.3 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain USP7_C2 PF14533.6 CBY23588.1 - 0.0074 16.0 0.7 0.016 14.9 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf-ribbon_3 PF13248.6 CBY23588.1 - 0.057 12.9 4.4 0.53 9.8 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CBY23588.1 - 0.23 11.5 1.5 24 5.0 0.1 2.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 CBY23588.1 - 0.44 10.7 4.0 24 5.1 0.0 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Ribosomal_S27e PF01667.17 CBY23588.1 - 0.49 10.1 3.4 4.6 7.0 0.6 2.8 2 0 0 2 2 2 0 Ribosomal protein S27 RA PF00788.23 CBY23589.1 - 0.0012 19.4 0.0 0.0049 17.5 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain GST_N_4 PF17172.4 CBY23590.1 - 0.0053 17.5 0.0 0.01 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 CBY23590.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sulfotransfer_1 PF00685.27 CBY23591.1 - 3.2e-13 49.8 0.0 4.5e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY23591.1 - 1.7e-05 25.3 0.0 0.00086 19.8 0.0 3.0 1 1 0 1 1 1 1 Sulfotransferase family PLAC8 PF04749.17 CBY23592.1 - 9.1e-08 33.0 33.5 1.6e-07 32.3 33.5 1.4 1 0 0 1 1 1 1 PLAC8 family MFS_1 PF07690.16 CBY23594.1 - 2.9e-41 141.6 20.1 3.5e-41 141.3 20.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY23594.1 - 1.6e-09 37.1 21.8 1.3e-07 30.8 21.8 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DHHC PF01529.20 CBY23594.1 - 1.1 9.4 10.0 4.6 7.3 1.2 3.3 3 0 0 3 3 3 0 DHHC palmitoyltransferase Septin PF00735.18 CBY23597.1 - 0.0013 18.0 0.1 0.0018 17.7 0.1 1.2 1 0 0 1 1 1 1 Septin Roc PF08477.13 CBY23597.1 - 0.0032 17.7 0.1 0.03 14.5 0.0 2.1 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CBY23597.1 - 0.0071 16.3 0.3 0.1 12.5 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CBY23597.1 - 0.0079 16.3 0.1 0.022 14.8 0.0 1.7 1 1 1 2 2 2 1 Dynamin family Ras PF00071.22 CBY23597.1 - 0.0081 15.8 0.1 0.089 12.4 0.1 2.1 1 1 0 1 1 1 1 Ras family AIG1 PF04548.16 CBY23597.1 - 0.012 14.9 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.23 CBY23597.1 - 0.02 15.0 0.3 0.046 13.8 0.3 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CBY23597.1 - 0.066 12.7 0.2 0.16 11.5 0.1 1.7 1 1 1 2 2 2 0 P-loop containing dynein motor region Sua5_yciO_yrdC PF01300.18 CBY23597.1 - 0.11 12.0 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Telomere recombination Ras PF00071.22 CBY23599.1 - 3.5e-14 52.7 0.0 3.1e-13 49.6 0.0 2.1 1 1 0 1 1 1 1 Ras family EF_assoc_2 PF08356.12 CBY23599.1 - 2.1e-10 40.5 0.0 4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 CBY23599.1 - 5.3e-10 39.5 0.1 2.9e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF_assoc_1 PF08355.12 CBY23599.1 - 4.4e-06 26.2 0.0 1.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 EF hand associated EF-hand_6 PF13405.6 CBY23599.1 - 0.0048 16.7 0.3 0.19 11.7 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY23599.1 - 0.0065 15.9 0.2 0.059 12.9 0.1 2.6 2 0 0 2 2 2 1 EF hand MMR_HSR1 PF01926.23 CBY23599.1 - 0.042 13.9 0.1 0.18 11.9 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY23599.1 - 0.043 14.2 0.0 0.081 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CBY23599.1 - 0.043 13.7 0.2 0.55 10.1 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 CBY23599.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CBY23599.1 - 0.07 12.6 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_14 PF13173.6 CBY23599.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CBY23599.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SURF4 PF02077.15 CBY23600.1 - 1.9e-93 312.9 8.6 2.4e-93 312.6 8.6 1.0 1 0 0 1 1 1 1 SURF4 family SURF2 PF05477.11 CBY23600.1 - 0.004 16.9 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) PRA1 PF03208.19 CBY23600.1 - 0.012 15.3 2.1 0.012 15.3 2.1 2.0 1 1 1 2 2 2 0 PRA1 family protein Phosphodiest PF01663.22 CBY23601.1 - 3.5e-57 194.6 0.1 5.9e-57 193.9 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 CBY23601.1 - 1.7e-05 25.1 10.4 3.8e-05 24.0 10.4 1.6 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.23 CBY23601.1 - 0.0019 17.7 0.0 0.012 15.1 0.0 2.1 2 1 0 2 2 2 1 Sulfatase CUT PF02376.15 CBY23602.1 - 5.6e-31 106.5 0.3 1e-30 105.7 0.3 1.4 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 CBY23602.1 - 4.4e-11 42.5 0.6 1e-10 41.3 0.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY23602.1 - 0.00038 20.3 0.0 0.00096 19.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Auts2 PF15336.6 CBY23602.1 - 0.026 14.7 2.6 0.045 13.9 2.6 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein HNF-1_N PF04814.13 CBY23602.1 - 0.94 10.1 5.3 0.27 11.8 1.6 1.9 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus AMP-binding PF00501.28 CBY23603.1 - 2.7e-29 102.0 0.0 9.4e-29 100.2 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Ribosomal_S19 PF00203.21 CBY23604.1 - 7.2e-30 102.7 0.1 1e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FKBP_C PF00254.28 CBY23605.1 - 4.4e-33 113.5 0.0 6e-29 100.2 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 CBY23605.1 - 2e-08 33.7 0.7 0.0025 17.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY23605.1 - 5.4e-06 26.1 0.3 0.073 13.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY23605.1 - 9e-06 25.3 0.0 0.88 9.3 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 CBY23605.1 - 1e-05 25.3 2.1 0.091 13.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY23605.1 - 0.014 16.0 0.1 1.9 9.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY23605.1 - 0.052 14.2 0.0 0.5 11.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBY23605.1 - 0.13 12.6 1.0 0.38 11.1 1.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CBY23605.1 - 0.66 10.1 2.2 0.69 10.0 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 UCH PF00443.29 CBY23606.1 - 5.6e-32 111.2 0.1 5.6e-32 111.2 0.1 1.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CBY23606.1 - 1.6e-10 41.1 6.5 3.1e-10 40.2 6.5 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CBY23606.1 - 0.00094 18.9 0.3 0.0057 16.3 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1923 PF09083.10 CBY23606.1 - 0.027 14.2 0.1 0.36 10.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1923) zf-UBP_var PF17807.1 CBY23606.1 - 0.43 10.4 2.7 0.86 9.4 2.7 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger ATP-synt_ab PF00006.25 CBY23607.1 - 4.7e-109 363.0 0.0 6.8e-109 362.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CBY23607.1 - 9.2e-43 145.0 0.0 1.6e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CBY23607.1 - 9.1e-16 58.1 1.4 2.1e-15 56.9 1.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Brix PF04427.18 CBY23608.1 - 1.9e-20 73.8 0.3 3.6e-20 72.9 0.3 1.5 1 0 0 1 1 1 1 Brix domain FAM60A PF15396.6 CBY23608.1 - 0.098 12.6 1.4 0.18 11.8 1.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF3340 PF11818.8 CBY23608.1 - 0.099 12.8 9.6 0.22 11.7 9.6 1.5 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Tetraspanin PF00335.20 CBY23609.1 - 8.8e-20 71.4 1.3 1e-19 71.2 1.3 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4579 PF15158.6 CBY23609.1 - 0.074 12.8 2.2 0.83 9.4 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) Phlebovirus_NSM PF07246.11 CBY23609.1 - 0.23 10.8 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF423 PF04241.15 CBY23609.1 - 0.93 9.7 8.8 1 9.6 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF423) MARVEL PF01284.23 CBY23609.1 - 1.6 8.8 13.9 1.9 8.5 13.7 1.6 1 1 0 1 1 1 0 Membrane-associating domain Ac76 PF05814.11 CBY23609.1 - 1.7 8.7 5.0 3.1 7.9 5.0 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) WD40 PF00400.32 CBY23610.1 - 4.9e-27 93.6 17.5 1e-06 29.3 0.1 10.0 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY23610.1 - 6.8e-20 71.2 0.1 0.005 17.1 0.0 8.3 5 1 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CBY23610.1 - 5.7e-08 33.0 0.1 9.6e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CBY23610.1 - 0.00021 20.4 0.2 1.5 7.7 0.0 3.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBY23610.1 - 0.018 14.4 0.0 7.5 5.8 0.0 3.6 4 0 0 4 4 4 0 WD40-like domain FHA PF00498.26 CBY23611.1 - 4.7e-11 42.9 0.0 9.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBY23611.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SSF PF00474.17 CBY23612.1 - 9.6e-33 113.6 16.4 1.3e-32 113.2 16.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2833 PF11090.8 CBY23612.1 - 0.14 12.5 0.2 24 5.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) CIA30 PF08547.12 CBY23614.1 - 5.1e-08 33.1 0.0 5.4e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Peptidase_M14 PF00246.24 CBY23619.1 - 1.3e-64 218.8 0.0 1.9e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CBY23619.1 - 3e-05 23.2 0.0 4.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Glyco_hydro_18 PF00704.28 CBY23620.1 - 9.5e-85 285.1 1.6 1.2e-84 284.7 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 CBY23620.1 - 1.6e-12 47.4 9.6 1.6e-12 47.4 9.6 2.7 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Lysyl_oxidase PF01186.17 CBY23621.1 - 4e-78 261.8 5.3 5.1e-78 261.4 5.3 1.1 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.11 CBY23621.1 - 0.11 12.8 0.0 0.47 10.7 0.1 2.0 2 0 0 2 2 2 0 CARDB Sulfotransfer_1 PF00685.27 CBY23622.1 - 5.6e-05 22.7 2.5 0.00081 18.9 2.5 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY23622.1 - 0.00059 20.3 0.2 0.003 18.0 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family DUF432 PF04254.13 CBY23622.1 - 0.035 14.3 0.1 0.081 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF432) CCDC84 PF14968.6 CBY23623.1 - 0.037 13.7 0.3 0.037 13.7 0.3 1.3 2 0 0 2 2 2 0 Coiled coil protein 84 Fibrillarin PF01269.17 CBY23623.1 - 0.073 12.2 0.6 0.48 9.5 0.1 2.0 2 0 0 2 2 2 0 Fibrillarin Sulfotransfer_1 PF00685.27 CBY23624.1 - 9.8e-14 51.5 2.2 8.8e-12 45.1 0.2 2.7 1 1 1 3 3 3 2 Sulfotransferase domain Sulfotransfer_2 PF03567.14 CBY23624.1 - 1.3e-12 48.2 2.0 6.9e-11 42.5 0.1 2.1 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_3 PF13469.6 CBY23624.1 - 1.6e-09 38.5 0.0 1e-08 35.8 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase family DDE_Tnp_1_7 PF13843.6 CBY23625.1 - 5.8e-23 81.8 0.0 9e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 CBY23625.1 - 0.0019 18.9 9.7 0.12 13.2 9.9 2.8 1 1 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon DDE_Tnp_1 PF01609.21 CBY23625.1 - 0.077 12.6 0.2 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE domain zf-AN1 PF01428.16 CBY23625.1 - 0.69 10.1 6.2 0.21 11.8 2.8 1.9 1 1 0 1 1 1 0 AN1-like Zinc finger zf-B_box PF00643.24 CBY23625.1 - 5.3 7.3 8.3 7.3 6.8 2.9 2.5 1 1 1 2 2 2 0 B-box zinc finger AAT PF03417.16 CBY23626.1 - 1.5 8.4 4.9 0.32 10.7 1.6 1.5 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase MCM2_N PF12619.8 CBY23626.1 - 6.2 7.1 12.9 7.1 6.9 3.7 2.5 1 1 1 2 2 2 0 Mini-chromosome maintenance protein 2 E1-E2_ATPase PF00122.20 CBY23627.1 - 2.8e-46 157.3 2.3 2.8e-46 157.3 2.3 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBY23627.1 - 1.6e-43 148.5 1.1 1.6e-43 148.5 1.1 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CBY23627.1 - 3.1e-25 88.1 0.0 5.9e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY23627.1 - 4.2e-19 69.7 0.4 6.4e-16 59.3 0.4 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBY23627.1 - 5.2e-13 48.5 0.0 9.7e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBY23627.1 - 3.8e-07 30.1 1.0 0.00077 19.3 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY23627.1 - 0.014 15.8 0.1 0.097 13.1 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase O-FucT PF10250.9 CBY23629.1 - 1.3e-09 38.2 0.3 3e-09 37.0 0.3 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aminotran_1_2 PF00155.21 CBY23630.1 - 3.9e-43 148.0 0.0 5.1e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBY23630.1 - 0.0055 16.0 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyr_redox_2 PF07992.14 CBY23630.1 - 0.066 12.4 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KIAA1430 PF13879.6 CBY23631.1 - 2.9e-28 98.6 9.9 2.9e-28 98.6 9.9 2.4 3 0 0 3 3 3 1 KIAA1430 homologue Cadherin_3 PF16184.5 CBY23632.1 - 8.2e-13 48.3 0.0 0.005 16.8 0.0 4.6 4 0 0 4 4 4 3 Cadherin-like Furin-like_2 PF15913.5 CBY23632.1 - 1.9e-09 37.7 50.5 4.1e-05 23.7 11.2 3.5 1 1 2 3 3 3 3 Furin-like repeat, cysteine-rich VSP PF03302.13 CBY23632.1 - 0.0026 16.7 46.6 0.077 11.8 10.5 3.6 1 1 2 3 3 3 3 Giardia variant-specific surface protein Calx-beta PF03160.14 CBY23633.1 - 1.1e-54 182.7 22.7 2.4e-14 53.3 0.2 6.3 5 1 1 6 6 6 5 Calx-beta domain Cadherin_3 PF16184.5 CBY23633.1 - 7.1e-25 87.2 2.1 8.6e-18 64.4 0.3 4.0 4 0 0 4 4 4 2 Cadherin-like DUF4843 PF16132.5 CBY23633.1 - 0.0033 17.0 1.4 4 7.0 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4843) CDC45 PF02724.14 CBY23634.1 - 0.22 9.8 5.8 0.23 9.7 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CBY23634.1 - 0.24 10.1 1.1 0.27 10.0 1.1 1.2 1 0 0 1 1 1 0 Presenilin Troponin PF00992.20 CBY23636.1 - 3.7e-35 121.2 10.4 4.7e-35 120.8 10.4 1.0 1 0 0 1 1 1 1 Troponin Cauli_DNA-bind PF03310.13 CBY23636.1 - 0.023 14.7 3.2 0.026 14.6 2.1 1.6 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Tup_N PF08581.10 CBY23636.1 - 0.024 15.0 0.9 0.055 13.8 0.3 2.0 2 0 0 2 2 2 0 Tup N-terminal Fes1 PF08609.10 CBY23636.1 - 0.17 12.8 2.8 5.9 7.8 2.8 2.2 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 v110 PF01639.17 CBY23637.1 - 0.061 13.2 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 Viral family 110 XAF1_C PF18608.1 CBY23637.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain DUF2975 PF11188.8 CBY23638.1 - 0.0064 16.4 0.2 0.0071 16.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) MARVEL PF01284.23 CBY23638.1 - 0.04 13.9 2.8 1.5 8.9 0.4 2.1 2 0 0 2 2 2 0 Membrane-associating domain DUF202 PF02656.15 CBY23638.1 - 0.063 13.7 2.3 5.3 7.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) SLATT_fungal PF18142.1 CBY23638.1 - 0.075 13.0 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain PIG-Y PF15159.6 CBY23638.1 - 3.2 8.7 8.0 0.61 11.1 3.3 2.0 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Trypsin PF00089.26 CBY23639.1 - 8.3e-43 146.7 0.1 2.2e-42 145.3 0.1 1.7 1 1 0 1 1 1 1 Trypsin Kelch_2 PF07646.15 CBY23639.1 - 2.6e-05 24.0 0.2 0.022 14.7 0.1 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY23639.1 - 0.0032 17.4 0.3 0.022 14.7 0.2 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF316 PF03761.15 CBY23639.1 - 0.02 14.4 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Kelch_5 PF13854.6 CBY23639.1 - 0.07 13.1 0.6 0.39 10.7 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY23639.1 - 0.076 13.3 0.0 3.7 8.0 0.0 3.0 2 0 0 2 2 2 0 Kelch motif Phospholip_A2_1 PF00068.19 CBY23641.1 - 4.6e-16 59.3 2.1 8.5e-16 58.4 2.1 1.5 1 0 0 1 1 1 1 Phospholipase A2 EGF_3 PF12947.7 CBY23642.1 - 3e-09 36.9 60.4 6.5e-05 23.0 11.2 6.7 6 0 0 6 6 6 3 EGF domain EGF_CA PF07645.15 CBY23642.1 - 1.2e-07 31.9 73.5 0.00023 21.3 14.4 5.9 6 0 0 6 6 6 3 Calcium-binding EGF domain EGF PF00008.27 CBY23642.1 - 0.0027 18.0 50.8 0.021 15.1 7.4 5.6 5 0 0 5 5 5 4 EGF-like domain Ldl_recept_a PF00057.18 CBY23642.1 - 0.012 15.8 0.4 0.012 15.8 0.4 7.2 8 0 0 8 8 8 0 Low-density lipoprotein receptor domain class A hEGF PF12661.7 CBY23642.1 - 1 10.1 41.6 0.27 11.9 1.7 6.4 5 1 0 5 5 5 0 Human growth factor-like EGF EGF_CA PF07645.15 CBY23644.1 - 1.3e-12 47.7 23.5 4.8e-08 33.1 11.3 5.0 4 1 2 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.7 CBY23644.1 - 1.2e-09 37.9 23.5 0.00053 19.9 0.5 4.6 4 0 0 4 4 4 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY23644.1 - 0.026 14.8 6.3 0.026 14.8 6.3 4.7 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CBY23644.1 - 9.4 6.5 33.2 0.35 11.1 7.5 5.1 2 2 2 4 4 4 0 EGF domain Troponin PF00992.20 CBY23645.1 - 9.5e-35 119.8 17.5 1.2e-34 119.5 17.5 1.0 1 0 0 1 1 1 1 Troponin LXG PF04740.12 CBY23645.1 - 0.036 13.8 1.7 0.052 13.2 1.4 1.4 1 1 0 1 1 1 0 LXG domain of WXG superfamily SIN1_PH PF16979.5 CBY23645.1 - 0.092 13.0 1.5 0.15 12.3 1.5 1.6 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology SLATT_fungal PF18142.1 CBY23645.1 - 0.16 12.0 0.6 0.29 11.1 0.6 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain GLTSCR1 PF15249.6 CBY23645.1 - 0.16 12.4 4.1 0.32 11.4 4.0 1.7 1 1 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein eIF3_N PF09440.10 CBY23645.1 - 0.5 10.8 6.8 2.2 8.7 5.2 2.0 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DivIC PF04977.15 CBY23645.1 - 0.58 10.0 8.1 0.74 9.6 2.1 2.5 1 1 1 2 2 2 0 Septum formation initiator CENP-H PF05837.12 CBY23645.1 - 1.4 9.4 9.0 0.077 13.4 2.2 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) MRPL52 PF18699.1 CBY23645.1 - 8.6 6.6 12.5 9.3 6.5 1.6 2.4 2 1 0 2 2 2 0 Mitoribosomal protein mL52 Astacin PF01400.24 CBY23646.1 - 4.1e-26 91.8 0.0 6.8e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY23646.1 - 1.2e-06 28.6 7.5 1.2e-06 28.6 7.5 4.9 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A DDHD PF02862.17 CBY23647.1 - 0.043 14.0 2.1 0.057 13.6 2.1 1.3 1 0 0 1 1 1 0 DDHD domain GREB1 PF15782.5 CBY23647.1 - 0.6 7.2 13.0 0.73 6.9 13.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 CBY23647.1 - 1.3 8.6 14.4 2.3 7.8 14.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.9 CBY23647.1 - 2 7.6 34.0 2.7 7.1 34.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Utp14 PF04615.13 CBY23647.1 - 2.4 6.6 6.6 2.9 6.4 6.6 1.0 1 0 0 1 1 1 0 Utp14 protein Sulfotransfer_2 PF03567.14 CBY23652.1 - 1.2e-15 58.1 3.6 2e-15 57.4 3.6 1.3 1 1 0 1 1 1 1 Sulfotransferase family FSA_C PF10479.9 CBY23653.1 - 0.16 10.1 2.7 0.19 9.8 2.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Telomere_reg-2 PF10193.9 CBY23654.1 - 0.074 13.5 0.7 0.27 11.7 0.2 2.1 2 0 0 2 2 2 0 Telomere length regulation protein End3 PF12761.7 CBY23654.1 - 4.2 7.5 12.2 0.53 10.4 0.4 3.1 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 RVT_1 PF00078.27 CBY23657.1 - 1.1e-26 93.7 0.0 2.2e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CBY23657.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Acyl-CoA_dh_1 PF00441.24 CBY23659.1 - 5.8e-40 136.9 0.2 8.2e-40 136.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY23659.1 - 1.2e-26 93.6 0.1 4.3e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY23659.1 - 8.9e-26 89.9 0.0 1.5e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY23659.1 - 1.7e-06 28.4 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CBY23659.1 - 0.015 15.8 0.0 0.058 13.9 0.0 2.1 2 1 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal SSF PF00474.17 CBY23660.1 - 5.2e-36 124.4 23.3 6.9e-36 124.0 23.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Sulfotransfer_1 PF00685.27 CBY23661.1 - 4.1e-11 42.9 2.9 4.9e-11 42.6 2.9 1.0 1 0 0 1 1 1 1 Sulfotransferase domain BAF250_C PF12031.8 CBY23661.1 - 0.0055 16.0 0.1 0.0069 15.7 0.1 1.1 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa BACK PF07707.15 CBY23661.1 - 0.071 13.2 0.5 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch PQQ PF01011.21 CBY23664.1 - 0.00022 21.0 0.1 0.0012 18.7 0.1 2.3 1 0 0 1 1 1 1 PQQ enzyme repeat PQQ_2 PF13360.6 CBY23664.1 - 0.012 15.3 0.5 0.14 11.8 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain KTSC PF13619.6 CBY23664.1 - 0.014 15.2 0.2 0.15 11.9 0.2 2.5 2 0 0 2 2 2 0 KTSC domain AAA_29 PF13555.6 CBY23664.1 - 0.021 14.6 1.0 0.063 13.0 0.1 2.3 2 1 0 2 2 2 0 P-loop containing region of AAA domain TctB PF07331.11 CBY23665.1 - 0.03 14.6 1.7 0.03 14.6 1.7 1.9 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family CRM1_repeat_3 PF18787.1 CBY23665.1 - 0.13 12.4 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 Connexin PF00029.19 CBY23666.1 - 2e-56 191.4 8.2 2.5e-56 191.1 8.2 1.1 1 0 0 1 1 1 1 Connexin Chordopox_G3 PF06129.12 CBY23666.1 - 0.17 12.6 1.6 6.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Chordopoxvirus G3 protein Orf78 PF06024.12 CBY23666.1 - 0.19 12.0 2.7 2 8.7 0.0 2.5 2 1 0 2 2 2 0 Orf78 (ac78) OAD_gamma PF04277.13 CBY23666.1 - 0.62 10.7 3.1 1.9 9.1 0.0 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Ac76 PF05814.11 CBY23666.1 - 4.1 7.5 6.1 1.5 8.9 0.1 2.6 3 0 0 3 3 3 0 Orf76 (Ac76) Glyoxal_oxid_N PF07250.11 CBY23667.1 - 0.09 12.0 0.0 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus C2-set_2 PF08205.12 CBY23668.1 - 9.2e-18 64.1 0.3 2e-12 47.0 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 CBY23668.1 - 2.7e-10 40.7 0.3 0.00081 19.9 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 CBY23668.1 - 8e-10 38.8 1.0 1.8e-05 24.9 0.3 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CBY23668.1 - 5.6e-09 36.2 0.0 0.0024 18.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY23668.1 - 8.6e-08 32.2 0.2 0.00015 21.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain C1-set PF07654.15 CBY23668.1 - 0.011 16.1 0.0 0.044 14.2 0.0 2.1 1 0 0 1 1 1 0 Immunoglobulin C1-set domain ECSCR PF15820.5 CBY23668.1 - 0.16 11.8 4.4 0.34 10.8 2.2 2.1 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator TraE PF05309.11 CBY23668.1 - 0.3 10.4 2.1 0.55 9.6 2.1 1.3 1 0 0 1 1 1 0 TraE protein Trypsin PF00089.26 CBY23669.1 - 3e-46 158.0 0.2 3e-46 158.0 0.2 1.5 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY23669.1 - 1e-06 29.7 0.0 2.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY23669.1 - 0.0065 16.1 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 Phage_min_cap2 PF06152.11 CBY23670.1 - 0.14 11.0 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Phage minor capsid protein 2 COesterase PF00135.28 CBY23672.1 - 2e-08 33.6 0.1 2.3e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Kelch_6 PF13964.6 CBY23672.1 - 0.034 14.5 0.7 0.21 11.9 0.1 2.2 1 1 1 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CBY23672.1 - 0.034 13.7 0.3 0.075 12.6 0.0 1.7 2 0 0 2 2 2 0 Kelch motif Spore_III_AB PF09548.10 CBY23673.1 - 0.2 11.7 2.9 0.12 12.5 0.6 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF2963 PF11178.8 CBY23673.1 - 1.2 8.9 5.7 0.18 11.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Mt_ATP-synt_B PF05405.14 CBY23673.1 - 1.6 8.3 8.0 0.21 11.2 0.9 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Kinesin PF00225.23 CBY23674.1 - 1.2e-112 376.1 0.1 1.7e-112 375.7 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 CBY23674.1 - 1.6e-42 145.7 7.6 4.9e-33 114.8 0.2 3.2 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 CBY23674.1 - 3.2e-31 109.1 0.0 9.3e-31 107.6 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 CBY23674.1 - 2.8e-23 82.5 0.1 6.8e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 CBY23674.1 - 5.8e-10 39.6 0.0 1.9e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 PH domain FHA PF00498.26 CBY23674.1 - 0.00014 22.1 0.0 0.00081 19.7 0.0 2.3 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 CBY23674.1 - 0.00027 21.3 0.1 0.007 16.8 0.1 2.8 1 1 0 1 1 1 1 Kinesin protein 1B Yop-YscD_cpl PF16697.5 CBY23674.1 - 0.0065 16.8 0.0 0.052 13.9 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kelch_6 PF13964.6 CBY23675.1 - 4.3e-08 33.2 3.1 0.12 12.7 0.0 4.7 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.6 CBY23675.1 - 5.4e-07 29.5 0.5 0.18 11.8 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CBY23675.1 - 9.1e-06 25.2 0.0 0.48 10.0 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY23675.1 - 5.6e-05 23.1 0.1 0.58 10.2 0.1 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY23675.1 - 0.0038 17.2 0.0 3.8 7.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif RCC1_2 PF13540.6 CBY23675.1 - 0.35 10.7 3.0 0.69 9.8 0.1 2.9 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Formyl_trans_C PF02911.18 CBY23676.1 - 0.13 12.5 0.1 3 8.1 0.0 2.9 3 0 0 3 3 3 0 Formyl transferase, C-terminal domain Ammonium_transp PF00909.21 CBY23677.1 - 3e-93 312.7 13.3 3.4e-93 312.5 13.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Peptidase_U4 PF03419.13 CBY23677.1 - 5.2 6.3 8.7 0.37 10.0 0.4 2.5 2 1 0 2 2 2 0 Sporulation factor SpoIIGA Glyco_hydro_79n PF03662.14 CBY23678.1 - 5.5e-54 183.3 0.9 6.9e-54 182.9 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_cc PF11790.8 CBY23678.1 - 0.0039 16.8 0.3 0.007 16.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core HTH_56 PF18662.1 CBY23678.1 - 0.036 14.2 0.3 0.08 13.0 0.3 1.5 1 0 0 1 1 1 0 Cch helix turn helix domain O-FucT PF10250.9 CBY23679.1 - 1e-10 41.8 0.0 5.6e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase MAPEG PF01124.18 CBY23681.1 - 0.13 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 MAPEG family Alpha_kinase PF02816.18 CBY23682.1 - 2.8e-51 174.2 2.8 2.8e-51 174.2 2.8 1.6 2 0 0 2 2 2 1 Alpha-kinase family Sel1 PF08238.12 CBY23682.1 - 0.0016 19.1 0.8 2 9.2 0.1 2.8 2 0 0 2 2 2 2 Sel1 repeat DUF5447 PF17525.2 CBY23682.1 - 0.018 15.5 0.1 0.18 12.3 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5447) Gal-3-0_sulfotr PF06990.11 CBY23683.1 - 2.6e-50 171.5 3.2 3e-50 171.3 3.2 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Galactosyl_T PF01762.21 CBY23684.1 - 2.1e-17 63.6 0.1 7e-17 61.9 0.1 1.7 1 1 0 1 1 1 1 Galactosyltransferase Phospholip_A2_1 PF00068.19 CBY23685.1 - 1.1e-05 25.9 0.0 1.1e-05 25.9 0.0 2.5 2 1 1 3 3 3 1 Phospholipase A2 Mucin PF01456.17 CBY23685.1 - 0.00043 20.3 22.8 0.001 19.1 22.8 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Sporozoite_P67 PF05642.11 CBY23685.1 - 0.087 10.9 0.5 0.1 10.6 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 CBY23685.1 - 0.93 7.6 23.6 1.4 7.0 23.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 CBY23685.1 - 1.3 7.1 7.9 1.8 6.6 7.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Tropomodulin PF03250.14 CBY23686.1 - 0.0018 18.3 1.3 0.0018 18.3 1.3 3.6 3 1 0 3 3 3 1 Tropomodulin LRR_6 PF13516.6 CBY23686.1 - 0.058 13.5 0.1 2 8.6 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat RIG-I_C PF18119.1 CBY23686.1 - 0.13 12.3 4.4 0.27 11.3 1.3 2.4 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain FumaraseC_C PF10415.9 CBY23686.1 - 0.24 11.9 0.7 3.7 8.0 0.1 3.2 2 1 1 3 3 3 0 Fumarase C C-terminus Ribosomal_L27A PF00828.19 CBY23686.1 - 0.46 11.2 4.2 4.3 8.0 3.1 2.8 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RED_C PF07807.11 CBY23686.1 - 0.69 10.4 4.9 1.9 9.0 0.1 2.6 2 0 0 2 2 2 0 RED-like protein C-terminal region UL42 PF17638.2 CBY23686.1 - 1.8 8.6 6.1 0.15 12.1 1.0 1.8 2 0 0 2 2 2 0 HCMV UL42 RAC_head PF16717.5 CBY23686.1 - 6.5 7.8 8.5 28 5.7 0.5 4.3 4 0 0 4 4 4 0 Ribosome-associated complex head domain DUF4483 PF14825.6 CBY23687.1 - 2.8e-39 134.4 0.1 4.1e-39 133.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) MukF_C PF17193.4 CBY23687.1 - 0.0078 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 MukF C-terminal domain Sulfotransfer_2 PF03567.14 CBY23688.1 - 6.6e-29 101.6 3.4 9.8e-29 101.0 3.4 1.2 1 0 0 1 1 1 1 Sulfotransferase family Glyco_hydro_9 PF00759.19 CBY23689.1 - 4.3e-231 767.5 8.3 2.4e-115 386.2 1.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 Trypsin PF00089.26 CBY23689.1 - 5.6e-29 101.5 0.0 1e-28 100.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin MIT PF04212.18 CBY23689.1 - 0.0029 17.6 0.2 4.2 7.5 0.0 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain HCV_NS5a_1a PF08300.13 CBY23689.1 - 0.12 12.5 2.2 4.8 7.4 0.2 2.7 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain CHASE8 PF17152.4 CBY23689.1 - 1.9 8.8 3.2 8.1 6.8 0.3 2.3 2 0 0 2 2 2 0 Periplasmic sensor domain Zona_pellucida PF00100.23 CBY23690.1 - 2.7e-33 115.8 2.2 4e-33 115.3 2.2 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Peptidase_M15_4 PF13539.6 CBY23691.1 - 7.5e-07 29.6 0.2 2.1e-06 28.2 0.2 1.7 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Peptidase_M15_3 PF08291.11 CBY23691.1 - 0.045 13.8 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase M15 Orthopox_C10L PF07020.11 CBY23691.1 - 2.6 8.8 15.8 1.6 9.5 13.4 1.9 1 1 1 2 2 2 0 Orthopoxvirus C10L protein EF-hand_7 PF13499.6 CBY23692.1 - 3.4e-17 62.7 3.0 1.3e-08 35.2 0.3 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY23692.1 - 3.5e-11 41.8 1.6 0.0022 17.4 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY23692.1 - 5.4e-11 41.5 1.6 0.005 16.7 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBY23692.1 - 4.1e-09 36.2 0.2 4.5e-07 29.6 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY23692.1 - 1e-05 24.8 1.7 0.11 12.0 0.1 3.6 4 0 0 4 4 4 3 EF hand EF-hand_11 PF08976.11 CBY23692.1 - 0.032 15.1 0.1 0.14 13.0 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain DUF5390 PF17365.2 CBY23692.1 - 0.047 14.0 0.2 0.076 13.3 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5390) Cadherin_C_2 PF16492.5 CBY23693.1 - 0.033 14.9 0.0 0.18 12.5 0.0 2.0 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Tad PF13400.6 CBY23693.1 - 0.064 13.6 0.4 0.1 12.9 0.4 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Ig_3 PF13927.6 CBY23694.1 - 3.4e-27 94.8 0.3 8.3e-11 42.3 0.0 4.9 4 1 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 CBY23694.1 - 1.6e-25 89.2 0.0 1.8e-09 37.8 0.0 5.1 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 CBY23694.1 - 5e-20 71.4 3.5 3.3e-08 33.5 0.0 5.5 5 1 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.25 CBY23694.1 - 7.1e-19 67.8 1.7 6.5e-06 26.2 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 CBY23694.1 - 1.9e-15 57.0 3.5 0.026 14.7 0.0 6.3 5 1 1 6 6 6 5 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY23694.1 - 1.2e-13 50.4 0.1 0.0005 19.6 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain Ig_5 PF16681.5 CBY23694.1 - 1.2e-08 35.3 0.1 0.1 13.0 0.0 4.3 4 0 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CBY23694.1 - 1e-06 28.9 0.5 3.9 7.8 0.0 4.8 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 CBY23694.1 - 4.2e-06 26.7 0.1 2.8 8.1 0.0 3.8 4 0 0 4 4 4 3 Izumo-like Immunoglobulin domain fn3 PF00041.21 CBY23694.1 - 2.6e-05 24.5 0.0 7.9e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY23694.1 - 0.11 13.0 0.1 0.48 11.0 0.0 2.2 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Zona_pellucida PF00100.23 CBY23695.1 - 6.8e-41 140.8 9.5 9.8e-41 140.2 9.5 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF2970 PF11174.8 CBY23695.1 - 0.051 13.4 2.7 0.093 12.6 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) 7tm_1 PF00001.21 CBY23696.1 - 1.2e-13 51.0 13.5 6.9e-13 48.5 8.1 2.6 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Tna_leader PF08053.11 CBY23696.1 - 0.5 10.4 3.5 1.1 9.3 0.2 2.7 2 0 0 2 2 2 0 Tryptophanase operon leader peptide SLATT_5 PF18160.1 CBY23697.1 - 0.017 14.4 0.0 0.021 14.2 0.0 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 EF-hand_6 PF13405.6 CBY23698.1 - 2e-07 30.4 0.2 0.0057 16.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY23698.1 - 2.2e-07 29.9 2.3 0.0074 15.8 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY23698.1 - 9.1e-06 24.9 4.0 0.013 14.9 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CBY23698.1 - 5.5e-05 23.5 1.4 0.00061 20.2 1.4 2.1 1 1 0 1 1 1 1 EF-hand domain pair Spa1_C PF18218.1 CBY23698.1 - 0.0023 18.3 0.1 0.0027 18.1 0.1 1.2 1 0 0 1 1 1 1 Lantibiotic immunity protein Spa1 C-terminal domain EF-hand_8 PF13833.6 CBY23698.1 - 0.026 14.4 2.0 0.067 13.1 1.0 2.0 1 1 1 2 2 2 0 EF-hand domain pair Borrelia_REV PF03978.13 CBY23698.1 - 0.036 14.0 0.1 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein RGS PF00615.19 CBY23700.1 - 1.3e-19 70.6 0.6 2.4e-19 69.7 0.6 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain CDC4_D PF16856.5 CBY23700.1 - 0.047 13.6 0.7 0.12 12.3 0.7 1.7 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain FGF PF00167.18 CBY23701.1 - 1.5e-22 80.0 0.3 1.8e-22 79.8 0.3 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 CBY23701.1 - 0.00018 21.7 0.1 0.0012 19.1 0.0 2.1 2 1 0 2 2 2 1 Fascin domain PSII_Pbs27 PF13326.6 CBY23702.1 - 0.57 10.5 5.9 13 6.1 0.5 3.2 3 0 0 3 3 3 0 Photosystem II Pbs27 DUF2680 PF10925.8 CBY23702.1 - 9.9 6.3 10.4 1.2 9.1 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Integrin_alpha2 PF08441.12 CBY23703.1 - 2.2e-14 53.2 0.8 9.5e-14 51.1 0.0 2.2 1 1 1 2 2 2 1 Integrin alpha FG-GAP PF01839.23 CBY23703.1 - 1.8e-06 27.9 1.9 1.8e-06 27.9 1.9 3.3 4 0 0 4 4 4 2 FG-GAP repeat VCBS PF13517.6 CBY23703.1 - 2.7e-05 24.7 3.8 0.00029 21.4 0.5 2.2 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 CBY23703.1 - 0.0064 16.7 6.8 0.81 10.0 0.4 4.9 5 0 0 5 5 5 1 FG-GAP repeat Spermine_synth PF01564.17 CBY23704.1 - 0.1 12.0 0.0 0.3 10.5 0.0 1.8 1 0 0 1 1 1 0 Spermine/spermidine synthase domain MT PF12777.7 CBY23705.1 - 2.2e-09 36.8 0.1 8.8e-09 34.8 0.1 1.9 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF3683 PF12447.8 CBY23705.1 - 1.6 8.8 5.8 2.6 8.2 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3683) DUF5600 PF18150.1 CBY23705.1 - 4.5 7.9 6.9 1.4 9.6 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5600) BLOC1_2 PF10046.9 CBY23705.1 - 5.9 7.3 19.4 11 6.4 0.5 6.0 4 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0184 PF03670.13 CBY23705.1 - 9.4 6.7 12.8 9.8 6.7 3.1 4.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) F5_F8_type_C PF00754.25 CBY23706.1 - 0.0055 16.8 0.0 0.043 13.9 0.0 2.3 2 1 0 2 2 2 1 F5/8 type C domain WD40 PF00400.32 CBY23709.1 - 1.8e-25 88.7 25.1 0.0011 19.7 0.2 10.2 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY23709.1 - 2.6e-07 30.9 7.7 2 8.8 0.0 6.9 5 1 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain nos_propeller PF18764.1 CBY23709.1 - 0.01 15.8 0.0 0.048 13.6 0.0 2.1 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat DUF1513 PF07433.11 CBY23709.1 - 0.16 11.0 0.0 2 7.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) GerD PF17898.1 CBY23711.1 - 0.14 12.1 3.6 0.18 11.7 1.7 2.1 2 1 0 2 2 2 0 Spore germination GerD central core domain Slu7 PF11708.8 CBY23712.1 - 9.4e-99 330.5 11.5 9.4e-99 330.5 11.5 3.3 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor SR-25 PF10500.9 CBY23712.1 - 0.0011 18.7 31.3 0.0011 18.7 31.3 2.6 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein zf-CCHC_4 PF14392.6 CBY23712.1 - 0.056 13.2 0.4 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2229 PF09989.9 CBY23712.1 - 5.8 6.5 6.3 13 5.3 6.3 1.6 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Prim-Pol PF09250.11 CBY23713.1 - 0.023 15.1 0.0 0.027 14.8 0.0 1.1 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal GTP1_OBG PF01018.22 CBY23714.1 - 4.8e-33 114.0 3.9 6.2e-33 113.6 3.9 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CBY23714.1 - 2.1e-15 56.8 0.0 4.1e-15 55.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY23714.1 - 3.9e-08 33.0 0.0 6.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Hydantoinase_B PF02538.14 CBY23714.1 - 1.3 7.3 4.4 2 6.7 4.4 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Ribosomal_L6 PF00347.23 CBY23715.1 - 2.2e-27 95.5 1.7 9.8e-14 51.8 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 OSCP PF00213.18 CBY23716.1 - 1.6e-36 126.0 0.2 2.1e-36 125.7 0.2 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF726 PF05277.12 CBY23716.1 - 0.045 12.7 0.4 0.05 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) BTB PF00651.31 CBY23717.1 - 2e-05 24.8 0.3 7.7e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 CBY23717.1 - 0.0021 18.2 0.1 0.007 16.5 0.0 1.9 2 0 0 2 2 2 1 MATH domain SK_channel PF03530.14 CBY23718.1 - 1.3e-47 160.5 0.6 1.3e-47 160.5 0.6 2.5 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.16 CBY23718.1 - 6.2e-37 125.6 8.3 1.3e-36 124.7 8.3 1.6 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 CBY23718.1 - 1.2e-13 50.8 3.5 1.2e-13 50.8 3.5 2.5 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 CBY23718.1 - 0.00013 21.3 3.8 0.00013 21.3 3.8 2.3 1 1 1 2 2 2 1 Ion transport protein IRK PF01007.20 CBY23718.1 - 0.017 14.9 3.4 0.017 14.9 3.4 2.5 3 1 1 4 4 4 0 Inward rectifier potassium channel transmembrane domain CD36 PF01130.21 CBY23721.1 - 5.8e-97 325.1 0.0 7.9e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 CD36 family tRNA-synt_2c PF01411.19 CBY23722.1 - 3.6e-208 692.6 0.0 3.6e-208 692.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CBY23722.1 - 4.8e-12 45.8 1.6 4.8e-12 45.8 0.2 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CBY23722.1 - 5.2e-09 36.7 1.5 5.2e-09 36.7 1.5 3.0 2 1 1 3 3 3 1 DHHA1 domain Mod_r PF07200.13 CBY23722.1 - 1.6 8.8 6.3 8.6 6.5 1.3 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1284 PF06935.11 CBY23722.1 - 6.6 7.2 5.9 8.1 6.9 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) RUN PF02759.19 CBY23723.1 - 2.2e-20 73.0 0.0 1.6e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 RUN domain DENN PF02141.21 CBY23723.1 - 1.3e-19 70.9 5.4 1.3e-19 70.9 5.4 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 CBY23723.1 - 1.5e-10 40.9 2.1 3.9e-10 39.6 2.1 1.7 1 0 0 1 1 1 1 dDENN domain PLAT PF01477.23 CBY23723.1 - 4.4e-10 40.1 0.0 9.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain uDENN PF03456.18 CBY23723.1 - 0.1 13.3 0.0 0.3 11.9 0.0 1.9 1 0 0 1 1 1 0 uDENN domain Cyclin_N PF00134.23 CBY23724.1 - 4.3e-18 65.3 0.1 2.6e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3456 PF11938.8 CBY23724.1 - 0.081 13.4 0.2 0.2 12.1 0.2 1.7 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP PCI PF01399.27 CBY23725.1 - 0.00031 21.2 0.1 0.00089 19.7 0.0 1.8 2 0 0 2 2 2 1 PCI domain PFK PF00365.20 CBY23726.1 - 8e-178 589.7 7.6 2.3e-96 322.5 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase fn2 PF00040.19 CBY23727.1 - 1.2e-07 31.9 0.7 1.2e-07 31.9 0.7 3.1 3 0 0 3 3 3 2 Fibronectin type II domain Thyroglobulin_1 PF00086.18 CBY23727.1 - 0.013 15.1 1.2 0.013 15.1 1.2 2.8 3 0 0 3 3 3 0 Thyroglobulin type-1 repeat Cys_rich_CWC PF14375.6 CBY23727.1 - 0.16 12.4 7.6 1 9.8 4.0 2.9 2 1 0 2 2 2 0 Cysteine-rich CWC Hist_deacetyl PF00850.19 CBY23728.1 - 2.4e-68 230.9 0.0 3.2e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain F_bP_aldolase PF01116.20 CBY23730.1 - 0.12 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Mem_trans PF03547.18 CBY23730.1 - 0.14 10.6 0.0 0.28 9.5 0.0 1.6 1 1 0 1 1 1 0 Membrane transport protein Far-17a_AIG1 PF04750.14 CBY23731.1 - 2e-07 30.6 7.1 2.4e-07 30.3 7.1 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Myosin_head PF00063.21 CBY23732.1 - 6.4e-185 616.2 0.9 8.6e-185 615.8 0.9 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 CBY23732.1 - 0.043 14.1 0.2 0.27 11.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 CBY23732.1 - 0.072 12.6 0.9 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Myosin_TH1 PF06017.13 CBY23733.1 - 3.2e-28 98.7 1.8 6.3e-28 97.7 1.8 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 CBY23733.1 - 5.9e-09 35.0 13.3 7.9e-05 22.1 0.5 3.6 3 0 0 3 3 3 2 IQ calmodulin-binding motif Glyco_transf_25 PF01755.17 CBY23734.1 - 7.5e-25 88.0 0.0 4.1e-23 82.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 CBY23734.1 - 8.6e-10 39.0 0.4 2.6e-09 37.5 0.4 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 CBY23734.1 - 7.2e-06 25.6 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CBY23734.1 - 0.0003 20.6 0.1 0.075 12.8 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 2 zf-RING_2 PF13639.6 CBY23735.1 - 7.9e-08 32.5 7.9 1.8e-07 31.4 7.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY23735.1 - 2.6e-07 30.4 8.5 4.8e-07 29.5 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY23735.1 - 4.8e-07 29.5 8.9 9.7e-07 28.6 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY23735.1 - 1.5e-06 27.9 4.6 3e-06 27.0 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY23735.1 - 3e-05 23.9 5.7 8.3e-05 22.5 5.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY23735.1 - 6.7e-05 22.7 7.3 0.00056 19.7 1.8 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBY23735.1 - 0.00034 20.8 6.3 0.0012 19.1 6.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY23735.1 - 0.00034 20.5 6.4 0.0012 18.7 6.6 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 CBY23735.1 - 0.0011 18.8 5.7 0.003 17.4 5.7 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 CBY23735.1 - 0.01 15.5 7.7 0.028 14.2 7.7 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.6 CBY23735.1 - 0.013 15.6 7.2 0.033 14.3 7.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 CBY23735.1 - 0.023 14.5 4.8 2.8 7.8 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_10 PF16685.5 CBY23735.1 - 0.11 12.6 3.7 0.22 11.7 3.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CBY23735.1 - 0.24 11.2 4.7 0.92 9.3 4.6 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 CBY23735.1 - 2.5 8.3 7.7 0.79 9.9 0.6 2.8 3 0 0 3 3 2 0 Zinc ribbon domain Ras PF00071.22 CBY23736.1 - 1.6e-17 63.6 0.0 2.3e-17 63.0 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBY23736.1 - 1.7e-13 50.9 0.1 1.7e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY23736.1 - 9e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 CBY23736.1 - 0.0062 16.8 0.1 0.61 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 CBY23736.1 - 0.0092 15.4 0.1 0.014 14.8 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY23736.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activat PF00158.26 CBY23736.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CBY23736.1 - 0.042 13.6 0.1 0.14 11.9 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CBY23736.1 - 0.051 14.1 0.2 0.13 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBY23736.1 - 0.094 12.0 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 CBY23736.1 - 0.11 12.8 0.2 0.19 12.1 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 CBY23736.1 - 0.13 12.7 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 RNA helicase MH2 PF03166.14 CBY23737.1 - 6.9e-54 182.9 0.3 1e-53 182.3 0.3 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CBY23737.1 - 1.4e-30 105.6 1.7 2.4e-30 104.8 1.7 1.4 1 0 0 1 1 1 1 MH1 domain Homeodomain PF00046.29 CBY23739.1 - 6.5e-05 22.7 1.7 0.0001 22.0 1.7 1.4 1 0 0 1 1 1 1 Homeodomain Rad51 PF08423.11 CBY23740.1 - 1.2e-112 375.3 0.1 1.8e-112 374.8 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBY23740.1 - 3.3e-10 39.9 0.2 5e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBY23740.1 - 5.1e-07 29.5 0.0 7.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBY23740.1 - 6.7e-05 22.4 0.8 0.00029 20.3 0.8 2.0 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 CBY23740.1 - 0.012 16.2 0.1 0.023 15.3 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3173 PF11372.8 CBY23740.1 - 0.034 14.0 0.1 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3173) GvpD PF07088.11 CBY23740.1 - 0.12 10.9 0.0 0.27 9.8 0.0 1.5 1 0 0 1 1 1 0 GvpD gas vesicle protein Pro_isomerase PF00160.21 CBY23742.1 - 8.7e-29 100.8 0.4 1.1e-28 100.5 0.4 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 CBY23745.1 - 6.6e-53 178.6 0.1 7.3e-53 178.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY23745.1 - 1.3e-20 73.8 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY23745.1 - 4.1e-09 36.1 0.1 4.5e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY23745.1 - 8.2e-05 22.7 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY23745.1 - 9.5e-05 22.0 0.1 0.00028 20.5 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY23745.1 - 0.001 19.0 0.6 0.74 9.7 0.3 2.2 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CBY23745.1 - 0.0012 18.1 0.1 0.13 11.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ank_2 PF12796.7 CBY23746.1 - 2.4e-17 63.3 2.6 6e-12 46.0 0.9 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY23746.1 - 2e-14 52.2 2.4 0.0048 17.3 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ion_trans PF00520.31 CBY23746.1 - 3.8e-14 52.5 22.5 1.2e-13 50.9 22.5 1.8 1 1 0 1 1 1 1 Ion transport protein Ank_5 PF13857.6 CBY23746.1 - 1.5e-13 50.6 4.7 2.4e-06 27.7 0.4 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY23746.1 - 1.7e-13 50.8 1.4 0.0051 17.4 0.1 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY23746.1 - 4e-13 49.2 5.1 0.011 16.2 0.2 5.5 5 0 0 5 5 5 4 Ankyrin repeat PKD_channel PF08016.12 CBY23746.1 - 4.3e-07 29.0 15.1 4.3e-07 29.0 15.1 2.0 2 1 0 2 2 2 1 Polycystin cation channel DUF4795 PF16043.5 CBY23746.1 - 0.0093 15.6 5.5 0.016 14.8 5.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) OmpH PF03938.14 CBY23746.1 - 0.046 14.1 8.9 3.2 8.1 9.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PIEZO PF15917.5 CBY23746.1 - 0.3 10.5 3.4 0.29 10.6 1.2 2.0 1 1 0 1 1 1 0 Piezo UPF0370 PF13980.6 CBY23747.1 - 0.17 12.0 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) RRM_1 PF00076.22 CBY23748.1 - 1.9e-84 277.5 1.2 1.1e-21 76.4 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBY23748.1 - 1.5e-29 101.9 0.6 7.9e-28 96.5 1.0 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM PF05172.13 CBY23748.1 - 2.2e-10 40.4 0.0 0.034 14.1 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CBY23748.1 - 1.7e-08 34.3 0.2 0.27 11.3 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CBY23748.1 - 2.4e-08 33.9 0.4 0.4 10.8 0.0 4.3 4 0 0 4 4 4 2 Limkain b1 RRM_7 PF16367.5 CBY23748.1 - 7.5e-07 29.2 0.2 2.5 8.3 0.0 5.3 4 3 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 CBY23748.1 - 4.7e-05 23.2 0.0 0.071 13.0 0.0 3.5 4 0 0 4 4 4 2 Occluded RNA-recognition motif SET_assoc PF11767.8 CBY23748.1 - 0.012 15.2 1.1 9.1 6.0 0.0 4.1 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated RNA_bind PF08675.11 CBY23748.1 - 0.015 15.3 0.1 0.19 11.8 0.0 3.0 4 0 0 4 4 4 0 RNA binding domain ENT PF03735.14 CBY23749.1 - 1.8e-17 63.1 0.1 4e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 ENT domain Sua5_yciO_yrdC PF01300.18 CBY23750.1 - 5.9e-39 133.4 0.0 1.8e-23 83.0 0.0 2.0 1 1 1 2 2 2 2 Telomere recombination GST_C_6 PF17171.4 CBY23750.1 - 0.14 11.9 0.5 11 5.9 0.0 3.4 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain NepR PF18557.1 CBY23750.1 - 2.3 7.9 5.1 4.7 6.9 0.4 2.5 2 0 0 2 2 2 0 Anti-sigma factor NepR Sin_N PF04801.13 CBY23751.1 - 4.1e-26 92.2 0.6 2.4e-25 89.6 0.6 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region TRAPPC10 PF12584.8 CBY23752.1 - 9.8e-09 35.1 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_7 PF13176.6 CBY23752.1 - 0.0087 16.0 0.1 0.031 14.3 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY23752.1 - 0.037 14.3 0.1 0.09 13.1 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY23752.1 - 0.14 12.4 0.4 0.34 11.1 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBY23752.1 - 0.38 11.7 1.2 0.84 10.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 CBY23753.1 - 7e-59 195.5 56.3 4.4e-16 58.4 6.9 5.1 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 CBY23753.1 - 4.6e-23 80.9 40.1 1.6e-09 37.9 2.0 6.9 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY23753.1 - 1.7e-20 73.3 9.5 1.3e-09 38.1 3.4 2.9 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 CBY23753.1 - 5.1e-12 46.2 0.0 1.1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CBY23753.1 - 6.9e-12 45.3 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 CBY23753.1 - 4e-10 39.7 0.0 1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY23753.1 - 4.1e-07 30.2 0.0 8.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 CBY23753.1 - 1.2e-06 28.2 21.4 0.0071 15.9 2.0 4.0 2 2 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CBY23753.1 - 1.9e-05 24.6 25.3 3.1 8.7 0.1 9.6 9 0 0 9 9 9 2 Leucine Rich Repeat V-set PF07686.17 CBY23753.1 - 0.00018 21.7 0.0 0.02 15.0 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_2 PF07723.13 CBY23753.1 - 0.019 15.6 2.2 0.72 10.6 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat Nop25 PF09805.9 CBY23753.1 - 0.081 13.4 0.1 0.081 13.4 0.1 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Pkinase_Tyr PF07714.17 CBY23754.1 - 5.4e-85 284.8 0.0 7.1e-85 284.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY23754.1 - 5.2e-43 147.3 0.0 7.2e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CBY23754.1 - 1.1e-24 86.3 0.0 2.3e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.7 CBY23754.1 - 8.6e-21 74.3 0.8 5.6e-14 52.5 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY23754.1 - 4.2e-15 55.9 3.5 4.6e-07 30.3 0.1 4.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY23754.1 - 9.4e-13 47.1 0.3 0.1 13.2 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CBY23754.1 - 1.5e-11 44.3 2.0 0.00012 22.3 0.0 4.6 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY23754.1 - 3.3e-09 36.8 2.2 0.41 11.2 0.2 4.9 4 0 0 4 4 4 4 Ankyrin repeat Kinase-like PF14531.6 CBY23754.1 - 1e-05 25.0 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY23754.1 - 0.011 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY23754.1 - 0.038 12.9 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain dCMP_cyt_deam_1 PF00383.23 CBY23755.1 - 7e-08 32.3 0.0 8.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBY23755.1 - 5.8e-05 22.9 0.0 6.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase DUF267 PF03268.14 CBY23756.1 - 0.055 12.3 0.1 0.079 11.8 0.1 1.2 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 DnaJ PF00226.31 CBY23758.1 - 8.6e-12 45.0 0.3 2e-11 43.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain CbiX PF01903.17 CBY23758.1 - 0.057 13.8 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 CbiX GDI PF00996.18 CBY23759.1 - 3.9e-36 124.5 0.2 2.9e-35 121.7 0.2 1.9 1 1 0 1 1 1 1 GDP dissociation inhibitor fn3 PF00041.21 CBY23760.1 - 1.7e-15 57.1 0.0 1.1e-11 44.9 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain fn3_2 PF16893.5 CBY23760.1 - 0.042 14.0 0.0 0.19 11.9 0.0 2.2 1 0 0 1 1 1 0 Fibronectin type III domain LpxI_N PF17930.1 CBY23760.1 - 0.22 11.4 0.0 0.83 9.6 0.0 1.7 1 1 1 2 2 2 0 LpxI N-terminal domain RVT_1 PF00078.27 CBY23761.1 - 8e-29 100.7 2.1 4.8e-28 98.2 0.0 2.8 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CBY23761.1 - 0.0009 19.1 2.6 0.0026 17.6 0.0 3.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Thymosin PF01290.20 CBY23762.1 - 3.4e-32 109.9 35.6 2.9e-12 46.1 0.7 6.1 3 2 3 6 6 6 5 Thymosin beta-4 family WH2 PF02205.20 CBY23762.1 - 0.1 12.5 0.0 2.1 8.3 0.0 2.9 3 0 0 3 3 3 0 WH2 motif Membr_traf_MHD PF10540.9 CBY23762.1 - 1.9 8.7 8.9 4 7.6 0.9 2.9 1 1 2 3 3 3 0 Munc13 (mammalian uncoordinated) homology domain DUF4522 PF15022.6 CBY23762.1 - 2 8.7 15.9 1 9.6 0.6 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF4522) BING4CT PF08149.11 CBY23763.1 - 2.2e-29 101.1 0.1 1.6e-28 98.3 0.0 2.5 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 CBY23763.1 - 0.0021 18.9 1.1 0.019 15.9 1.1 2.6 1 1 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.8 CBY23763.1 - 0.0027 16.4 0.1 0.0048 15.6 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBY23763.1 - 0.02 13.9 1.4 0.069 12.1 1.4 1.8 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CBY23763.1 - 0.06 11.9 0.0 1.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain DCX PF03607.17 CBY23764.1 - 5.1e-21 74.5 0.0 5.5e-09 36.0 0.0 2.6 2 0 0 2 2 2 2 Doublecortin DUF4722 PF15849.5 CBY23764.1 - 0.079 12.7 0.1 0.079 12.7 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4722) Mis14 PF08641.12 CBY23764.1 - 0.091 13.1 0.9 21 5.4 0.2 3.3 3 0 0 3 3 3 0 Kinetochore protein Mis14 like Gal-3-0_sulfotr PF06990.11 CBY23765.1 - 7.7e-62 209.5 1.1 7.7e-61 206.2 1.1 1.9 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Oxidored-like PF09791.9 CBY23766.1 - 3.1e-12 45.9 1.2 4.5e-12 45.4 1.2 1.2 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 CBY23766.1 - 0.024 14.6 1.9 0.041 13.8 1.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Syntaphilin PF15290.6 CBY23767.1 - 0.00033 20.4 11.9 0.0011 18.7 11.9 1.9 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp ATG16 PF08614.11 CBY23767.1 - 0.3 11.3 16.7 0.063 13.5 12.1 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 CBY23767.1 - 0.5 9.7 9.3 1.2 8.4 9.3 1.6 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 CBY23767.1 - 1.3 7.9 15.9 2.2 7.1 15.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec7 PF01369.20 CBY23768.1 - 1e-62 211.1 0.0 2.4e-62 209.9 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CBY23768.1 - 7.8e-21 74.6 4.4 7.8e-21 74.6 4.4 4.2 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CBY23768.1 - 0.031 12.4 0.0 0.056 11.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of Mon2 protein DUF5453 PF17534.2 CBY23769.1 - 0.013 15.5 1.3 2.2 8.2 0.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5453) DUF3007 PF11460.8 CBY23769.1 - 0.11 12.7 1.2 1.1 9.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) PP2C PF00481.21 CBY23771.1 - 6.2e-06 26.0 0.0 7.7e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Trigger_N PF05697.13 CBY23771.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) PP2C PF00481.21 CBY23773.1 - 1.3e-27 97.1 0.0 1.9e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 CBY23773.1 - 3.2e-05 24.3 0.0 5.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain DUF4547 PF15080.6 CBY23773.1 - 0.046 13.4 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) DUF3484 PF11983.8 CBY23774.1 - 4 8.6 6.4 10 7.3 6.4 1.8 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch ER_lumen_recept PF00810.18 CBY23775.1 - 3.5e-54 183.6 8.0 3.5e-54 183.6 8.0 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CBY23775.1 - 0.029 14.1 13.0 0.19 11.5 0.3 3.1 4 0 0 4 4 4 0 PQ loop repeat ATP-grasp_2 PF08442.10 CBY23776.1 - 2.3e-69 233.0 0.0 3.7e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CBY23776.1 - 1.3e-26 93.3 0.8 2.3e-26 92.5 0.8 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CBY23776.1 - 1.9e-11 43.9 0.0 3.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CBY23776.1 - 5.6e-06 26.3 0.0 9.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 CBY23776.1 - 0.08 13.2 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Pkinase_Tyr PF07714.17 CBY23777.1 - 6.6e-77 258.3 0.0 1.8e-76 256.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY23777.1 - 1.5e-33 116.3 0.0 2.6e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Recep_L_domain PF01030.24 CBY23777.1 - 1.3e-28 99.3 2.7 4e-16 59.1 0.4 2.6 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.20 CBY23777.1 - 2.5e-15 56.7 35.4 2.5e-15 56.7 35.4 4.6 2 1 1 3 3 3 1 Furin-like cysteine rich region GF_recep_IV PF14843.6 CBY23777.1 - 1.7e-05 24.6 78.9 2.3e-05 24.2 29.0 4.3 2 2 2 4 4 4 3 Growth factor receptor domain IV TMEMspv1-c74-12 PF11044.8 CBY23777.1 - 0.013 15.4 0.1 0.043 13.8 0.2 1.8 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PDZ_6 PF17820.1 CBY23778.1 - 9.2e-12 44.6 0.6 4.8e-11 42.3 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CBY23778.1 - 1.8e-08 34.6 0.0 4.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Glutaredoxin PF00462.24 CBY23778.1 - 1.3e-06 28.5 0.0 8.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin PDZ_2 PF13180.6 CBY23778.1 - 0.00016 22.0 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SH3BGR PF04908.15 CBY23778.1 - 0.008 16.3 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Zn_ribbon_recom PF13408.6 CBY23778.1 - 0.019 15.4 2.1 0.048 14.2 2.1 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain FYVE PF01363.21 CBY23778.1 - 2.9 8.1 10.0 7.6 6.7 10.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger DnaJ_CXXCXGXG PF00684.19 CBY23778.1 - 4.6 7.7 16.9 0.19 12.1 4.8 2.5 1 1 1 2 2 2 0 DnaJ central domain EGF_CA PF07645.15 CBY23779.1 - 4.8e-191 618.8 637.3 1.3e-09 38.1 8.8 38.0 38 1 1 39 39 39 33 Calcium-binding EGF domain cEGF PF12662.7 CBY23779.1 - 1.2e-124 405.6 381.1 2e-09 37.2 1.2 38.3 40 0 0 40 40 40 32 Complement Clr-like EGF-like EGF PF00008.27 CBY23779.1 - 1.1e-54 182.3 581.8 2.7e-05 24.4 5.9 39.9 39 1 0 39 39 39 29 EGF-like domain FXa_inhibition PF14670.6 CBY23779.1 - 1.2e-52 175.9 586.2 1e-07 32.1 8.8 38.0 35 4 4 39 39 39 27 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CBY23779.1 - 1e-29 102.4 542.2 5.9e-09 36.0 12.1 38.8 36 3 1 37 37 37 24 EGF domain hEGF PF12661.7 CBY23779.1 - 1.5e-25 88.9 567.0 0.00088 19.8 6.2 44.5 44 4 0 44 44 44 28 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 CBY23779.1 - 1.5e-10 41.2 451.0 0.014 15.7 4.7 35.3 33 3 1 34 34 34 23 Pvs28 EGF domain EGF_2 PF07974.13 CBY23779.1 - 7.9e-05 22.9 14.3 7.9e-05 22.9 14.3 39.0 35 3 3 38 38 38 15 EGF-like domain EGF_MSP1_1 PF12946.7 CBY23779.1 - 0.0028 17.7 6.1 0.0028 17.7 6.1 32.1 32 3 3 35 35 35 10 MSP1 EGF domain 1 NHL PF01436.21 CBY23779.1 - 3.3 7.9 7.0 36 4.6 0.3 4.3 3 0 0 3 3 3 0 NHL repeat I-set PF07679.16 CBY23780.1 - 0 1525.5 125.8 7.7e-18 64.3 0.0 53.0 52 1 1 53 53 53 50 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY23780.1 - 4e-283 914.9 21.7 1.4e-12 48.0 0.0 50.0 51 0 0 51 51 50 40 Immunoglobulin domain ig PF00047.25 CBY23780.1 - 7e-136 442.8 46.1 3.5e-07 30.3 0.0 36.9 39 0 0 39 39 39 25 Immunoglobulin domain Ig_2 PF13895.6 CBY23780.1 - 5.4e-135 440.0 21.5 1.5e-07 31.6 0.0 39.6 43 0 0 43 43 40 26 Immunoglobulin domain fn3 PF00041.21 CBY23780.1 - 4.9e-84 276.8 0.0 1.8e-11 44.2 0.0 10.2 9 0 0 9 9 9 8 Fibronectin type III domain V-set PF07686.17 CBY23780.1 - 1.2e-52 176.7 33.5 0.0008 19.6 0.0 33.0 34 5 0 34 34 34 8 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CBY23780.1 - 1.3e-22 79.7 29.6 0.018 15.1 0.0 19.1 23 0 0 23 23 20 4 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 CBY23780.1 - 2.8e-20 72.2 13.3 0.85 9.7 0.0 19.8 23 0 0 23 23 21 4 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 CBY23780.1 - 2.8e-15 56.1 3.4 1.2 9.2 0.0 16.8 20 0 0 20 20 19 1 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.5 CBY23780.1 - 6.8e-14 51.9 29.4 0.49 10.7 0.1 18.5 21 0 0 21 21 20 3 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 CBY23780.1 - 9.9e-10 37.8 0.1 1.1 8.9 0.0 9.3 8 0 0 8 8 8 2 Immunoglobulin domain Ig_5 PF16681.5 CBY23780.1 - 4.3e-08 33.4 43.4 0.45 10.9 0.0 18.8 23 0 0 23 23 16 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.5 CBY23780.1 - 1.5e-06 28.7 11.2 0.58 10.8 0.0 9.1 8 1 0 8 8 8 2 Purple acid Phosphatase, N-terminal domain Receptor_2B4 PF11465.8 CBY23780.1 - 2.3e-06 27.8 12.7 5.6 7.2 0.0 14.4 19 0 0 19 19 17 1 Natural killer cell receptor 2B4 C1-set PF07654.15 CBY23780.1 - 5.1e-06 26.8 32.3 0.62 10.5 0.0 14.9 17 0 0 17 17 14 2 Immunoglobulin C1-set domain THB PF18362.1 CBY23780.1 - 4.3e-05 23.0 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 Tri-helix bundle domain Herpes_gE PF02480.16 CBY23780.1 - 0.00033 19.5 21.3 1.1 8.0 0.0 11.4 12 2 2 15 15 15 2 Alphaherpesvirus glycoprotein E Ig_C17orf99 PF17736.1 CBY23780.1 - 0.0006 19.8 0.4 2.4 8.3 0.0 5.6 7 0 0 7 7 6 1 C17orf99 Ig domain Fn3-like PF14310.6 CBY23780.1 - 0.44 10.7 4.6 4.6 7.4 0.0 5.1 5 0 0 5 5 4 0 Fibronectin type III-like domain Rhodanese PF00581.20 CBY23781.1 - 1e-07 32.5 0.1 2.2e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Peptidase_M23_N PF18421.1 CBY23781.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain Pkinase PF00069.25 CBY23782.1 - 5e-57 193.3 0.1 1.3e-56 191.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23782.1 - 7.2e-28 97.6 0.0 1.7e-27 96.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase cNMP_binding PF00027.29 CBY23782.1 - 4.6e-25 87.5 0.4 8.2e-15 54.7 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 CBY23782.1 - 9.1e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY23782.1 - 0.00045 19.1 0.0 0.00063 18.6 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Pfk_N PF18468.1 CBY23782.1 - 0.031 14.7 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast RXLR_WY PF18634.1 CBY23782.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain Rhodanese PF00581.20 CBY23783.1 - 1e-07 32.5 0.1 2.2e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Peptidase_M23_N PF18421.1 CBY23783.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain Pkinase PF00069.25 CBY23785.1 - 8.1e-57 192.6 0.1 1.9e-56 191.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 CBY23785.1 - 6.5e-33 112.7 0.4 2.8e-15 56.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY23785.1 - 1.1e-27 96.9 0.0 2.5e-27 95.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY23785.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY23785.1 - 0.00068 18.5 0.0 0.0011 17.9 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Pfk_N PF18468.1 CBY23785.1 - 0.041 14.3 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast Tir_receptor_N PF07490.11 CBY23785.1 - 0.2 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Homeodomain PF00046.29 CBY23786.1 - 1.9e-21 75.6 4.4 1.9e-21 75.6 4.4 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY23786.1 - 0.75 9.7 3.0 0.59 10.1 0.1 2.3 2 0 0 2 2 2 0 Homeobox KN domain TFIIA PF03153.13 CBY23786.1 - 1.7 8.5 12.4 2 8.3 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HMA PF00403.26 CBY23787.1 - 1.5e-70 233.6 22.6 3.2e-14 53.1 0.2 8.7 8 0 0 8 8 8 8 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 CBY23787.1 - 3.3e-52 176.7 1.4 3.3e-52 176.7 1.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBY23787.1 - 5.1e-52 177.2 0.4 1.5e-51 175.6 0.4 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY23787.1 - 0.00017 22.0 0.0 0.0005 20.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 CBY23787.1 - 0.0026 18.1 19.5 8 6.9 0.1 8.1 8 0 0 8 8 8 2 BFD-like [2Fe-2S] binding domain Vert_HS_TF PF06546.11 CBY23787.1 - 0.0093 15.7 0.6 3.3 7.3 0.0 2.5 2 0 0 2 2 2 2 Vertebrate heat shock transcription factor Hydrolase_3 PF08282.12 CBY23787.1 - 0.021 14.6 6.1 0.051 13.3 2.1 3.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PHD_4 PF16866.5 CBY23787.1 - 0.77 9.9 9.7 12 6.1 0.2 4.2 3 1 1 4 4 4 0 PHD-finger C1_1 PF00130.22 CBY23787.1 - 8.2 6.4 15.3 0.38 10.7 0.1 4.0 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cyclin_N PF00134.23 CBY23789.1 - 1.3e-13 50.8 0.0 2.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CBY23789.1 - 1e-12 48.7 0.1 1.5e-12 48.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin MIF PF01187.18 CBY23792.1 - 2.2e-28 98.8 0.0 2.5e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) zf-SNAP50_C PF12251.8 CBY23793.1 - 7.3e-63 211.9 4.6 1e-62 211.4 4.6 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal YccV-like PF08755.11 CBY23794.1 - 0.00083 19.8 0.1 0.0035 17.8 0.0 2.1 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like DUF525 PF04379.14 CBY23795.1 - 1.4e-18 66.9 0.3 5.9e-18 64.9 0.3 2.0 1 1 0 1 1 1 1 ApaG domain YccV-like PF08755.11 CBY23795.1 - 0.01 16.3 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like SOSSC PF15925.5 CBY23796.1 - 0.0003 22.0 0.0 0.00035 21.8 0.0 1.1 1 0 0 1 1 1 1 SOSS complex subunit C GCS PF03074.16 CBY23796.1 - 0.043 13.2 0.2 0.045 13.1 0.2 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase PMSR PF01625.21 CBY23796.1 - 0.068 13.3 0.4 0.079 13.1 0.4 1.0 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase DEAD PF00270.29 CBY23797.1 - 1.2e-41 142.4 0.1 1.3e-40 139.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY23797.1 - 1.6e-26 92.8 0.9 5e-26 91.2 0.6 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY23797.1 - 2.5e-06 27.6 0.0 6.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY23797.1 - 0.027 13.7 0.1 0.044 13.0 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Homeobox_KN PF05920.11 CBY23798.1 - 1.5e-14 53.6 0.1 3.6e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY23798.1 - 1.1e-06 28.4 1.9 1.2e-06 28.3 0.2 1.9 2 0 0 2 2 2 1 Homeodomain KASH_CCD PF14662.6 CBY23799.1 - 0.0042 16.9 23.7 0.0042 16.9 23.7 8.7 2 2 7 9 9 9 3 Coiled-coil region of CCDC155 or KASH FAM184 PF15665.5 CBY23801.1 - 0.0004 20.2 11.3 0.00069 19.5 11.3 1.4 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B YabA PF06156.13 CBY23801.1 - 0.0093 16.6 2.9 0.0093 16.6 2.9 2.4 1 1 1 2 2 2 1 Initiation control protein YabA MtrF PF09472.10 CBY23801.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Syntaxin-6_N PF09177.11 CBY23801.1 - 0.21 12.2 9.4 0.66 10.6 8.8 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 CBY23801.1 - 0.21 11.6 16.6 0.12 12.4 11.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ALMT PF11744.8 CBY23801.1 - 1 8.2 6.8 1.4 7.7 6.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3496 PF12001.8 CBY23801.1 - 1 9.7 11.3 11 6.5 7.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3496) DUF4407 PF14362.6 CBY23801.1 - 1.7 7.9 12.3 2 7.7 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VSG_B PF13206.6 CBY23801.1 - 2 7.6 11.7 2.3 7.4 11.7 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF4559 PF15112.6 CBY23801.1 - 3.6 7.2 14.9 0.55 9.8 11.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) V_ATPase_I PF01496.19 CBY23801.1 - 9.4 4.0 12.4 11 3.7 12.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SH3BGR PF04908.15 CBY23802.1 - 4.9e-06 26.6 0.7 4.9e-06 26.6 0.7 1.8 2 1 0 2 2 2 1 SH3-binding, glutamic acid-rich protein APG6 PF04111.12 CBY23803.1 - 3.1e-45 154.3 0.4 9.9e-45 152.7 0.0 1.8 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 CBY23803.1 - 2.9e-07 31.1 21.8 4.7e-07 30.4 21.8 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region LCD1 PF09798.9 CBY23803.1 - 0.00021 20.0 2.4 0.00024 19.8 2.4 1.2 1 0 0 1 1 1 1 DNA damage checkpoint protein V_ATPase_I PF01496.19 CBY23803.1 - 0.0034 15.4 4.5 0.0042 15.1 4.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HALZ PF02183.18 CBY23803.1 - 0.011 15.9 9.9 3.6 7.9 0.7 3.9 4 0 0 4 4 3 0 Homeobox associated leucine zipper MscS_porin PF12795.7 CBY23803.1 - 0.015 14.8 11.3 0.022 14.3 11.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Atg14 PF10186.9 CBY23803.1 - 0.066 12.3 5.0 0.12 11.5 5.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 CBY23803.1 - 0.093 13.1 3.2 11 6.5 0.1 3.2 3 1 1 4 4 4 0 Lipoprotein leucine-zipper AKNA PF12443.8 CBY23803.1 - 0.12 13.0 0.4 0.12 13.0 0.4 2.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor MPS2 PF17060.5 CBY23803.1 - 0.2 10.9 8.2 0.27 10.4 8.2 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Exonuc_VII_L PF02601.15 CBY23803.1 - 0.21 11.1 5.5 0.29 10.7 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 CBY23803.1 - 0.28 11.6 16.3 0.42 11.0 15.0 1.8 1 1 1 2 2 2 0 Fez1 YABBY PF04690.13 CBY23803.1 - 0.44 11.1 3.6 2.4 8.7 3.6 2.2 1 1 0 1 1 1 0 YABBY protein Polbeta PF18765.1 CBY23803.1 - 0.63 10.2 4.4 0.41 10.8 0.4 2.5 1 1 3 4 4 4 0 Polymerase beta, Nucleotidyltransferase FapA PF03961.13 CBY23803.1 - 0.84 8.2 8.5 1.2 7.7 8.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fzo_mitofusin PF04799.13 CBY23803.1 - 1.1 8.7 8.6 0.31 10.6 4.2 2.1 1 1 1 2 2 2 0 fzo-like conserved region CpXC PF14353.6 CBY23803.1 - 1.5 8.9 5.4 3.7 7.6 5.4 1.6 1 1 0 1 1 1 0 CpXC protein Seryl_tRNA_N PF02403.22 CBY23803.1 - 2.8 8.2 15.1 1 9.6 12.1 1.9 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF812 PF05667.11 CBY23803.1 - 3.3 6.5 20.1 11 4.8 20.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ZapB PF06005.12 CBY23803.1 - 3.7 8.1 20.1 1.3 9.5 5.2 3.0 1 1 1 2 2 2 0 Cell division protein ZapB zf-C4H2 PF10146.9 CBY23803.1 - 4.5 7.5 10.6 1.5 9.1 7.6 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF1664 PF07889.12 CBY23803.1 - 5.2 7.1 6.6 18 5.4 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 CBY23803.1 - 8.3 6.5 10.1 19 5.3 10.1 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Sad1_UNC PF07738.13 CBY23804.1 - 3.2e-09 36.9 0.1 7.1e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal 7TM_GPCR_Srw PF10324.9 CBY23804.1 - 0.012 14.9 0.4 0.019 14.3 0.4 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw MbeD_MobD PF04899.12 CBY23804.1 - 0.037 14.1 1.3 0.098 12.8 1.3 1.8 1 0 0 1 1 1 0 MbeD/MobD like DUF4446 PF14584.6 CBY23804.1 - 0.13 12.3 5.5 0.92 9.5 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Baculo_PEP_C PF04513.12 CBY23804.1 - 0.2 11.7 7.2 0.16 12.0 3.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 CBY23804.1 - 0.23 10.4 11.0 0.22 10.4 1.4 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF16 PF01519.16 CBY23804.1 - 0.35 11.4 6.1 3.9 8.0 5.2 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 HrpB7 PF09486.10 CBY23804.1 - 1.8 9.0 4.6 0.59 10.5 0.9 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) eIF-1a PF01176.19 CBY23805.1 - 2.4e-12 46.5 0.0 4e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TSA PF03249.13 CBY23805.1 - 0.1 11.3 1.4 0.13 11.0 1.4 1.1 1 0 0 1 1 1 0 Type specific antigen SKA2 PF16740.5 CBY23806.1 - 0.018 14.8 2.0 0.018 14.8 2.0 1.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 CcmH PF03918.14 CBY23806.1 - 0.13 11.5 2.3 0.15 11.3 2.3 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein UPF0242 PF06785.11 CBY23806.1 - 0.29 11.2 7.1 0.34 11.0 7.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CBY23806.1 - 0.57 10.9 6.9 2 9.1 6.9 1.8 1 1 0 1 1 1 0 Initiation control protein YabA FlaC_arch PF05377.11 CBY23806.1 - 1.1 9.7 4.7 0.53 10.7 0.8 2.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 CBY23806.1 - 1.9 8.8 7.1 4.2 7.6 0.8 2.2 1 1 1 2 2 2 0 Haemolysin XhlA GAS PF13851.6 CBY23807.1 - 0.0034 16.8 53.8 0.022 14.1 15.6 4.4 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 CBY23807.1 - 0.029 14.7 6.2 0.029 14.7 6.2 7.0 3 2 4 8 8 8 0 Csm1 N-terminal domain bZIP_2 PF07716.15 CBY23807.1 - 0.094 12.8 0.6 0.094 12.8 0.6 8.0 8 1 2 10 10 10 0 Basic region leucine zipper DUF4989 PF16379.5 CBY23807.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4989) FRB_dom PF08771.11 CBY23807.1 - 0.62 10.5 6.5 0.42 11.1 2.9 2.6 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain Fez1 PF06818.15 CBY23807.1 - 4.9 7.6 51.0 0.53 10.7 21.8 3.7 1 1 2 3 3 3 0 Fez1 Atg14 PF10186.9 CBY23807.1 - 6.3 5.8 56.9 0.12 11.5 18.2 3.7 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 RasGAP PF00616.19 CBY23808.1 - 0.032 13.9 6.1 0.098 12.4 6.1 1.7 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DUF2664 PF10867.8 CBY23808.1 - 0.086 13.3 3.7 0.18 12.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) Selenoprotein_S PF06936.11 CBY23808.1 - 0.23 11.3 10.1 0.33 10.7 10.1 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DDHD PF02862.17 CBY23808.1 - 0.27 11.4 4.1 0.29 11.3 4.1 1.2 1 0 0 1 1 1 0 DDHD domain Podoplanin PF05808.11 CBY23808.1 - 0.29 11.2 1.3 1.4 9.1 0.0 2.0 2 0 0 2 2 2 0 Podoplanin EF-hand_6 PF13405.6 CBY23809.1 - 1e-09 37.6 0.2 4.2e-05 23.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBY23809.1 - 7.8e-08 32.7 2.2 9.4e-08 32.4 1.0 1.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY23809.1 - 4.3e-07 29.0 0.2 0.0058 16.1 0.0 2.7 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY23809.1 - 0.00056 19.7 1.5 0.11 12.3 0.0 2.7 2 2 0 2 2 2 2 EF-hand domain pair TERB2 PF15101.6 CBY23809.1 - 0.0058 16.7 0.1 0.0067 16.5 0.1 1.1 1 0 0 1 1 1 1 Telomere-associated protein TERB2 EF-hand_5 PF13202.6 CBY23809.1 - 0.011 15.2 0.1 0.25 10.9 0.0 2.6 3 0 0 3 3 3 0 EF hand Cas9_a PF18470.1 CBY23809.1 - 0.083 12.4 0.2 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain CAAP1 PF15335.6 CBY23809.1 - 0.12 13.0 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 DUF4316 PF14195.6 CBY23809.1 - 0.87 9.4 6.0 7 6.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4316) Med21 PF11221.8 CBY23812.1 - 4.5e-27 95.1 1.7 5.7e-27 94.7 1.7 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Pox_F16 PF04708.12 CBY23812.1 - 0.047 13.1 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein PspB PF06667.12 CBY23812.1 - 0.25 11.4 1.2 0.5 10.5 1.2 1.5 1 0 0 1 1 1 0 Phage shock protein B ZapB PF06005.12 CBY23812.1 - 2.2 8.8 6.0 15 6.1 0.2 2.6 1 1 1 2 2 2 0 Cell division protein ZapB RMP PF14996.6 CBY23813.1 - 4.6e-41 140.6 8.0 4.6e-41 140.6 8.0 1.7 1 1 1 2 2 2 1 Retinal Maintenance SH3BP5 PF05276.14 CBY23814.1 - 2.1e-75 253.5 24.0 3.3e-75 252.8 24.0 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) RasGAP_C PF03836.15 CBY23814.1 - 0.0031 17.7 0.5 0.0031 17.7 0.5 3.2 2 1 1 3 3 3 1 RasGAP C-terminus Pox_A_type_inc PF04508.12 CBY23814.1 - 0.013 15.3 1.6 1.7 8.6 0.0 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Tup_N PF08581.10 CBY23814.1 - 2 8.8 14.8 8.9 6.7 0.9 3.8 2 1 1 3 3 3 0 Tup N-terminal FlaC_arch PF05377.11 CBY23814.1 - 2.2 8.7 6.0 5.9 7.4 0.3 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2797 PF10977.8 CBY23814.1 - 3.2 7.6 7.6 3.3 7.5 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) NDK PF00334.19 CBY23815.1 - 1.8e-35 121.9 0.0 1.4e-34 119.0 0.0 2.0 2 0 0 2 2 2 1 Nucleoside diphosphate kinase Methyltransf_25 PF13649.6 CBY23815.1 - 1.4e-08 35.3 0.1 3.3e-07 30.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY23815.1 - 2.7e-08 33.8 0.1 8.7e-08 32.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY23815.1 - 2.5e-06 28.0 0.0 1.3e-05 25.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY23815.1 - 6.6e-06 26.8 0.0 1.7e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBY23815.1 - 0.035 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain JmjC PF02373.22 CBY23816.1 - 1.6e-11 44.7 1.4 3.3e-10 40.4 1.4 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CBY23816.1 - 7.9e-09 35.6 0.0 6.1e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JHD PF17811.1 CBY23816.1 - 9e-08 32.6 0.3 1.9e-07 31.6 0.3 1.5 1 0 0 1 1 1 1 Jumonji helical domain F-box-like PF12937.7 CBY23816.1 - 8.3e-07 28.8 0.1 2.3e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY23816.1 - 0.00019 21.2 0.0 0.00051 19.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 CBY23816.1 - 0.037 14.1 0.0 29 5.1 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Cupin_2 PF07883.11 CBY23816.1 - 0.12 12.1 0.1 3.6 7.4 0.0 2.5 3 0 0 3 3 3 0 Cupin domain zf-C2H2_6 PF13912.6 CBY23817.1 - 0.0002 21.3 3.6 0.014 15.4 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CBY23817.1 - 0.00069 20.2 39.6 0.013 16.3 0.2 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY23817.1 - 0.00071 19.9 23.4 0.0027 18.1 0.5 6.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY23817.1 - 0.029 14.8 0.2 0.029 14.8 0.2 6.4 6 1 0 6 6 6 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 CBY23817.1 - 0.032 14.1 3.6 0.085 12.8 0.1 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 CBY23817.1 - 0.056 13.7 15.5 0.96 9.8 0.6 3.9 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CBY23818.1 - 0.029 14.1 11.6 0.079 12.7 0.1 4.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CBY23818.1 - 0.037 14.5 4.1 0.037 14.5 4.1 6.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type DpnI PF06044.12 CBY23818.1 - 0.26 10.9 6.1 0.12 12.0 3.0 2.0 2 0 0 2 2 2 0 Dam-replacing family zf-met PF12874.7 CBY23818.1 - 0.68 10.4 11.2 2.1 8.9 1.8 3.4 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY23818.1 - 0.86 10.6 37.9 0.2 12.6 3.0 6.5 6 1 0 6 6 6 0 C2H2-type zinc finger OrsD PF12013.8 CBY23818.1 - 0.87 10.1 0.0 0.87 10.1 0.0 5.2 2 2 3 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D FOXP-CC PF16159.5 CBY23818.1 - 4.2 8.1 10.8 60 4.4 0.0 3.8 3 1 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 CBY23819.1 - 0.00031 21.0 37.3 0.00045 20.5 0.7 6.2 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY23819.1 - 0.012 16.4 0.7 0.012 16.4 0.7 6.4 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.7 CBY23819.1 - 0.061 13.7 18.0 0.62 10.5 0.8 5.0 4 1 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBY23819.1 - 0.099 13.1 26.5 0.33 11.5 0.3 6.1 6 1 0 6 6 6 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 CBY23819.1 - 0.18 12.1 20.6 0.5 10.7 5.7 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CBY23819.1 - 0.2 12.0 16.6 0.67 10.3 1.6 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 CBY23819.1 - 0.21 12.1 0.3 0.21 12.1 0.3 5.5 2 2 3 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-MYST PF17772.1 CBY23819.1 - 0.68 9.6 14.7 1.9 8.1 0.1 4.0 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 CBY23819.1 - 0.82 10.0 11.0 5.7 7.3 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 CBY23819.1 - 1.8 8.6 6.6 0.81 9.8 0.9 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger FHA PF00498.26 CBY23820.1 - 2.7e-15 56.5 0.0 5.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBY23820.1 - 3.6e-08 33.6 0.0 8.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Dicer_dimer PF03368.14 CBY23820.1 - 6.9e-05 22.9 0.0 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain HNH_4 PF13395.6 CBY23820.1 - 0.032 14.2 0.1 0.082 12.8 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease Pro_isomerase PF00160.21 CBY23821.1 - 0.00056 20.2 0.0 0.0007 19.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 CBY23822.1 - 1.5e-10 41.6 0.0 1.7e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_3 PF01596.17 CBY23823.1 - 1.5e-06 27.5 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 CBY23823.1 - 1.9e-05 25.6 0.0 3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBY23823.1 - 0.0047 16.9 0.1 0.0078 16.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CBY23823.1 - 0.026 14.3 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3772 PF12607.8 CBY23824.1 - 0.53 10.1 5.1 0.91 9.3 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3772) LRR_4 PF12799.7 CBY23825.1 - 7.4e-22 77.1 16.3 2.9e-07 30.7 3.7 4.4 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY23825.1 - 1.8e-15 56.4 14.6 4.9e-08 32.6 5.5 4.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 CBY23825.1 - 2.1e-07 30.6 9.9 0.00065 19.2 1.7 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CBY23825.1 - 1.4e-06 28.1 16.6 0.14 12.8 0.5 6.8 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_5 PF13306.6 CBY23825.1 - 0.00072 19.5 5.2 0.0026 17.7 4.3 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) DUF1699 PF08004.11 CBY23825.1 - 0.022 14.4 0.8 0.99 9.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) Beta_helix PF13229.6 CBY23825.1 - 0.045 13.6 0.2 0.088 12.7 0.1 1.6 1 1 1 2 2 2 0 Right handed beta helix region LRR_6 PF13516.6 CBY23825.1 - 3.8 7.8 15.9 0.18 11.9 1.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat Fe-S_biosyn PF01521.20 CBY23826.1 - 1e-17 64.3 0.0 1.1e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ATG16 PF08614.11 CBY23827.1 - 4.9e-06 26.9 74.9 0.0014 18.9 16.9 3.5 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) zf-C2H2 PF00096.26 CBY23827.1 - 5.6e-05 23.4 1.4 0.00015 22.0 1.4 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY23827.1 - 0.0011 19.7 2.1 0.0015 19.2 1.0 1.9 2 0 0 2 2 1 1 C2H2-type zinc finger Fib_alpha PF08702.10 CBY23827.1 - 0.0083 16.3 11.7 0.0083 16.3 11.7 4.9 1 1 4 5 5 5 1 Fibrinogen alpha/beta chain family BRE1 PF08647.11 CBY23827.1 - 0.012 15.7 10.0 0.012 15.7 10.0 7.1 2 1 4 6 6 2 0 BRE1 E3 ubiquitin ligase zf-Di19 PF05605.12 CBY23827.1 - 0.022 15.0 0.1 0.066 13.5 0.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY23827.1 - 0.031 14.7 0.0 0.074 13.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type CENP-F_leu_zip PF10473.9 CBY23827.1 - 0.032 14.2 87.1 0.038 14.0 24.5 4.8 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-H2C2_2 PF13465.6 CBY23827.1 - 0.12 12.8 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double domain SlyX PF04102.12 CBY23827.1 - 0.54 10.9 49.0 3.6 8.3 6.8 6.7 2 2 3 6 6 6 0 SlyX Spc7 PF08317.11 CBY23827.1 - 0.89 8.4 74.8 0.026 13.4 16.7 3.9 1 1 4 5 5 5 0 Spc7 kinetochore protein GAS PF13851.6 CBY23827.1 - 1.2 8.4 79.3 0.063 12.6 18.4 5.1 1 1 2 3 3 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 CBY23827.1 - 2.3 8.3 45.4 0.29 11.2 2.2 5.3 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Filament PF00038.21 CBY23827.1 - 3.3 7.2 66.5 0.029 14.0 19.4 4.1 1 1 2 3 3 3 0 Intermediate filament protein FPP PF05911.11 CBY23827.1 - 5.3 5.1 79.1 1 7.5 31.3 2.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4200 PF13863.6 CBY23827.1 - 9.3 6.7 80.1 0.042 14.3 12.7 5.5 2 1 2 5 5 5 0 Domain of unknown function (DUF4200) FYVE PF01363.21 CBY23828.1 - 3.9e-18 65.4 13.2 8.3e-18 64.3 13.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger CENP-F_leu_zip PF10473.9 CBY23828.1 - 0.00055 20.0 12.9 0.00055 20.0 12.9 2.7 1 1 1 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspA_IM30 PF04012.12 CBY23828.1 - 0.0039 16.8 25.0 0.39 10.3 10.8 2.8 1 1 1 2 2 2 2 PspA/IM30 family DUF3584 PF12128.8 CBY23828.1 - 0.02 12.4 31.3 0.051 11.1 8.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) RNA_POL_M_15KD PF02150.16 CBY23828.1 - 0.066 13.1 11.2 1.6 8.7 1.2 3.5 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit DUF4201 PF13870.6 CBY23828.1 - 0.14 11.9 34.6 0.071 12.8 6.0 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Zn-ribbon_8 PF09723.10 CBY23828.1 - 0.15 12.2 10.4 16 5.7 2.1 2.7 1 1 1 2 2 2 0 Zinc ribbon domain ERM PF00769.19 CBY23828.1 - 0.17 11.7 44.1 0.65 9.8 15.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 CBY23828.1 - 0.69 10.6 33.5 1.4 9.6 1.7 3.8 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 CBY23828.1 - 1 9.9 47.8 7.9 7.0 6.7 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 CBY23828.1 - 1.6 8.8 19.8 0.3 11.1 7.7 3.2 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) IBR PF01485.21 CBY23828.1 - 1.6 9.0 12.2 0.33 11.2 7.5 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain ATG16 PF08614.11 CBY23828.1 - 3.9 7.6 37.5 0.9 9.7 24.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 CBY23828.1 - 5.2 7.2 17.1 4.1 7.5 1.3 3.0 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 CBY23828.1 - 8.9 7.0 28.6 26 5.5 9.5 3.8 1 1 2 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 CBY23828.1 - 9 6.7 37.7 18 5.7 13.6 2.4 1 1 1 2 2 2 0 Fez1 FUSC PF04632.12 CBY23828.1 - 10 4.5 5.7 14 4.1 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family RRM_1 PF00076.22 CBY23829.1 - 3e-10 39.8 0.0 5.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CBY23829.1 - 7.2e-07 29.1 1.7 2.8e-06 27.2 1.7 2.1 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CBY23829.1 - 3e-05 24.7 0.0 8.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Torus domain Nup35_RRM_2 PF14605.6 CBY23829.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY23829.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif zf-CCCH_4 PF18044.1 CBY23829.1 - 0.0021 17.8 2.2 0.0055 16.5 2.2 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBY23829.1 - 0.0059 16.5 2.4 0.0059 16.5 2.4 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CBY23829.1 - 0.0074 16.7 2.2 0.012 16.0 0.4 2.5 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger FYVE PF01363.21 CBY23829.1 - 0.28 11.4 6.0 0.036 14.2 1.4 2.0 2 0 0 2 2 2 0 FYVE zinc finger Rpn3_C PF08375.11 CBY23830.1 - 1e-19 70.7 3.4 1e-19 70.7 3.4 2.5 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CBY23830.1 - 1.1e-19 70.9 0.1 9e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 PCI domain DnaJ PF00226.31 CBY23831.1 - 6.6e-09 35.8 0.1 1.3e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Innexin PF00876.18 CBY23832.1 - 0.0047 16.3 0.9 0.0097 15.2 0.9 1.5 1 1 0 1 1 1 1 Innexin Spexin PF15171.6 CBY23833.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin Trypsin PF00089.26 CBY23834.1 - 1.9e-74 250.2 3.6 1.1e-53 182.3 0.5 2.1 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.11 CBY23834.1 - 8.5e-10 39.0 0.0 0.00079 19.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) TSP_1 PF00090.19 CBY23834.1 - 3.1e-07 30.5 8.6 3.1e-07 30.5 8.6 2.1 2 0 0 2 2 2 1 Thrombospondin type 1 domain Antimicrobial_6 PF08036.11 CBY23834.1 - 0.71 10.0 4.4 3.1 7.9 4.4 2.1 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide EGF_CA PF07645.15 CBY23835.1 - 1.1e-08 35.1 14.5 1.3e-05 25.3 2.0 5.3 4 1 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.7 CBY23835.1 - 0.00015 21.6 1.8 0.00015 21.6 1.8 4.7 4 1 0 4 4 4 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY23835.1 - 0.0071 16.6 3.6 0.0071 16.6 3.6 5.7 3 2 1 4 4 4 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CBY23835.1 - 0.02 15.1 1.8 0.02 15.1 1.8 6.0 4 2 0 4 4 4 0 EGF domain Lectin_C PF00059.21 CBY23836.1 - 0.0038 18.0 6.0 0.0098 16.6 0.1 2.8 2 1 1 3 3 3 2 Lectin C-type domain V-set PF07686.17 CBY23837.1 - 1.1e-05 25.6 0.1 4.1e-05 23.7 0.1 2.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY23837.1 - 1.2e-05 25.3 0.2 0.00027 21.0 0.1 3.0 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 CBY23837.1 - 3.8e-05 24.2 0.1 0.019 15.6 0.1 3.2 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 CBY23837.1 - 0.0035 17.5 0.1 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CBY23837.1 - 0.0052 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Orthoreo_P10 PF07204.11 CBY23837.1 - 0.0062 16.5 0.6 0.016 15.1 0.6 1.6 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 CBY23837.1 - 0.0071 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Ig_2 PF13895.6 CBY23837.1 - 0.0083 16.4 0.1 0.71 10.2 0.0 3.1 2 1 0 2 2 2 1 Immunoglobulin domain EphA2_TM PF14575.6 CBY23837.1 - 0.012 16.5 0.0 0.037 14.9 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 CBY23837.1 - 0.03 14.2 1.9 0.037 13.9 0.3 2.0 2 0 0 2 2 2 0 TMIE protein Izumo-Ig PF16706.5 CBY23837.1 - 0.089 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Cadherin_C_2 PF16492.5 CBY23837.1 - 0.094 13.5 0.0 0.34 11.7 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal PRIMA1 PF16101.5 CBY23837.1 - 0.18 11.8 0.4 7.9 6.5 0.0 2.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 FAM163 PF15069.6 CBY23837.1 - 0.32 11.4 2.7 0.43 11.0 0.4 2.3 2 0 0 2 2 2 0 FAM163 family Nucleolin_bd PF16725.5 CBY23837.1 - 0.4 10.4 2.5 0.69 9.6 1.8 1.7 1 1 0 1 1 1 0 Nucleolin binding domain DUF4349 PF14257.6 CBY23837.1 - 0.42 10.0 1.2 19 4.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) dsrm PF00035.26 CBY23838.1 - 1.6e-33 115.2 0.0 6.4e-16 58.8 0.0 3.4 3 0 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.7 CBY23838.1 - 5.5e-14 52.2 2.8 6e-05 23.2 0.1 4.2 3 2 0 3 3 3 3 double strand RNA binding domain from DEAD END PROTEIN 1 Staufen_C PF16482.5 CBY23838.1 - 6e-10 39.3 0.9 4e-08 33.4 0.0 2.9 2 1 1 3 3 3 1 Staufen C-terminal domain LPP20 PF02169.16 CBY23838.1 - 0.018 15.4 0.2 4.9 7.6 0.0 2.9 3 0 0 3 3 3 0 LPP20 lipoprotein RIIa PF02197.17 CBY23839.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Nitr_red_assoc PF09655.10 CBY23839.1 - 0.033 14.8 0.4 0.038 14.6 0.4 1.1 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF2014 PF09427.10 CBY23839.1 - 0.083 12.2 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) SURF2 PF05477.11 CBY23840.1 - 5.9e-33 114.5 8.3 7.4e-33 114.2 8.3 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DUF5099 PF17025.5 CBY23840.1 - 0.061 13.7 0.1 0.061 13.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5099) EF-hand_1 PF00036.32 CBY23841.1 - 1.5e-26 89.9 13.7 2.9e-06 26.4 0.4 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBY23841.1 - 5.4e-24 84.4 6.1 3.3e-13 49.9 0.7 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY23841.1 - 9.5e-21 71.9 7.5 6.7e-05 22.5 0.4 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBY23841.1 - 3.3e-20 70.6 7.8 0.00012 21.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CBY23841.1 - 7.5e-16 57.7 9.2 3.2e-06 26.9 0.4 4.2 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY23841.1 - 1.5e-07 31.7 0.3 0.0072 16.6 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY23841.1 - 1.3e-05 25.0 5.6 0.044 13.7 0.1 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CBY23841.1 - 0.0053 16.7 4.1 9.3 6.1 0.1 3.8 2 2 2 4 4 4 2 Caleosin related protein Dockerin_1 PF00404.18 CBY23841.1 - 0.02 15.1 2.3 0.36 11.0 0.4 3.1 3 1 1 4 4 4 0 Dockerin type I domain EF-hand_9 PF14658.6 CBY23841.1 - 0.039 14.3 0.4 2.4 8.6 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain Ras PF00071.22 CBY23842.1 - 5.6e-66 221.1 0.3 6.7e-66 220.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY23842.1 - 5.9e-36 123.3 0.2 1.1e-35 122.5 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY23842.1 - 3e-16 59.4 0.3 3.7e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY23842.1 - 1.7e-06 27.6 0.2 2.1e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY23842.1 - 5.1e-06 26.1 0.1 9.7e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBY23842.1 - 8.1e-05 22.1 0.1 0.0001 21.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY23842.1 - 0.00046 20.2 0.1 0.00069 19.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY23842.1 - 0.0015 18.4 0.4 1 9.3 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 CBY23842.1 - 0.065 12.7 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3963 PF13124.6 CBY23842.1 - 0.12 12.4 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) PduV-EutP PF10662.9 CBY23842.1 - 0.18 11.6 0.6 0.94 9.2 0.6 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoLip_ATPase_C PF16212.5 CBY23843.1 - 2e-81 273.5 28.4 5e-81 272.1 28.4 1.7 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBY23843.1 - 1.2e-22 79.3 2.6 3.5e-22 77.9 2.6 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CBY23843.1 - 1.5e-08 34.6 0.0 6.5e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY23843.1 - 2.9e-08 34.3 0.1 0.00076 19.8 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY23843.1 - 0.0049 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CBY23843.1 - 0.012 15.1 0.0 0.012 15.1 0.0 2.7 3 0 0 3 3 3 0 E1-E2 ATPase DUF3487 PF11990.8 CBY23843.1 - 0.54 10.1 0.0 0.54 10.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3487) DUF3899 PF13038.6 CBY23843.1 - 6.6 7.3 13.3 0.77 10.3 7.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF4594 PF15266.6 CBY23844.1 - 4.6e-05 23.8 14.8 4.6e-05 23.8 14.8 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4594) YEATS PF03366.16 CBY23846.1 - 0.00046 20.1 0.1 0.00089 19.2 0.1 1.6 1 0 0 1 1 1 1 YEATS family Ntox22 PF15527.6 CBY23846.1 - 0.16 12.0 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 22 CTP_transf_like PF01467.26 CBY23847.1 - 1.9e-23 83.2 0.0 4.7e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase-like A_deaminase PF00962.22 CBY23847.1 - 3.4e-11 43.0 0.0 5.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase NTP_transferase PF00483.23 CBY23847.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase Tcp11 PF05794.13 CBY23848.1 - 1.3e-57 195.8 0.0 1.6e-57 195.6 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 Trns_repr_metal PF02583.17 CBY23848.1 - 0.049 14.0 0.1 0.34 11.3 0.0 2.5 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor 5_nucleotid_C PF02872.18 CBY23849.1 - 1.6e-29 103.1 0.0 2.4e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CBY23849.1 - 3.3e-14 53.9 0.4 7.1e-14 52.8 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA_lid_7 PF17867.1 CBY23850.1 - 0.047 13.9 0.3 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Midasin AAA lid domain zf-C2H2 PF00096.26 CBY23850.1 - 0.55 10.8 7.6 7.9 7.1 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4604 PF15377.6 CBY23851.1 - 3.3e-19 70.0 17.5 4.1e-19 69.6 17.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) TMEM208_SND2 PF05620.11 CBY23852.1 - 4e-26 91.8 0.8 7.4e-26 90.9 0.8 1.4 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 RINGv PF12906.7 CBY23853.1 - 4.7e-12 45.8 11.2 4.7e-12 45.8 11.2 2.1 2 0 0 2 2 2 1 RING-variant domain FANCL_C PF11793.8 CBY23853.1 - 0.016 15.4 7.5 0.032 14.4 7.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 CBY23853.1 - 0.062 13.7 11.5 0.044 14.1 9.0 2.0 2 0 0 2 2 2 0 Ring finger domain SpoIIIAH PF12685.7 CBY23854.1 - 0.004 17.0 4.6 0.0053 16.6 4.6 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein NPR3 PF03666.13 CBY23854.1 - 0.016 14.0 1.7 0.02 13.7 1.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2207 PF09972.9 CBY23854.1 - 0.018 13.9 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Presenilin PF01080.17 CBY23854.1 - 0.054 12.3 1.4 0.067 11.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CBY23854.1 - 0.073 13.1 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Astro_capsid_p2 PF16580.5 CBY23855.1 - 0.0032 17.0 0.7 0.0043 16.5 0.7 1.2 1 0 0 1 1 1 1 C-terminal tail of astrovirus capsid projection or spike SNase PF00565.17 CBY23856.1 - 5.4e-56 187.7 0.2 3.7e-20 72.4 0.0 5.6 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 CBY23856.1 - 8.5e-13 48.4 0.0 2.1e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Tudor domain zf-H2C2_5 PF13909.6 CBY23856.1 - 2.2e-08 33.7 16.9 3.2e-05 23.6 0.6 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBY23856.1 - 8.5e-05 23.1 19.0 0.27 12.2 0.1 6.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY23856.1 - 0.00012 22.3 1.4 0.00012 22.3 1.4 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 CBY23856.1 - 0.014 15.9 30.1 0.15 12.6 0.8 5.6 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 CBY23856.1 - 0.023 14.4 12.5 0.33 10.6 0.2 4.4 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-RAG1 PF10426.9 CBY23856.1 - 0.036 14.2 0.8 0.036 14.2 0.8 2.1 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain Ribosomal_S9 PF00380.19 CBY23858.1 - 3.1e-32 111.6 0.6 3.5e-32 111.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L6e PF01159.19 CBY23859.1 - 1.1e-36 125.8 2.4 1.2e-36 125.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 CBY23859.1 - 2.2e-06 27.8 6.3 2.2e-06 27.8 6.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L6, N-terminal domain P30 PF07390.11 CBY23859.1 - 0.038 14.1 0.1 0.038 14.1 0.1 1.6 2 0 0 2 2 2 0 Mycoplasma P30 protein Nuc_sug_transp PF04142.15 CBY23860.1 - 8.9e-126 419.3 22.2 1.1e-125 419.0 22.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBY23860.1 - 6.6e-07 29.6 33.0 0.00035 20.8 15.0 2.4 2 1 0 2 2 2 2 EamA-like transporter family PSP PF04046.16 CBY23862.1 - 1.2e-15 57.0 0.1 2.2e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 PSP DUF1242 PF06842.12 CBY23863.1 - 1.6e-18 66.2 1.9 2.2e-18 65.7 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Alpha_kinase PF02816.18 CBY23864.1 - 2.9e-53 180.7 0.1 6e-53 179.7 0.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family DUF4512 PF14975.6 CBY23865.1 - 7.8e-18 65.1 15.5 1.1e-16 61.4 15.5 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) Phospholip_A2_1 PF00068.19 CBY23866.1 - 5.2e-13 49.4 1.3 5.2e-13 49.4 1.3 1.7 2 0 0 2 2 2 1 Phospholipase A2 Metallophos PF00149.28 CBY23867.1 - 3.9e-34 119.0 0.0 5.9e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Hemocyanin_N PF03722.14 CBY23868.1 - 0.17 12.4 1.0 0.68 10.5 1.0 2.0 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain Thioredoxin PF00085.20 CBY23869.1 - 1.4e-28 98.9 0.1 1.6e-28 98.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBY23869.1 - 3.1e-05 24.1 0.1 4.1e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CBY23869.1 - 0.00086 18.7 0.0 0.00091 18.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBY23869.1 - 0.0012 19.3 0.4 0.024 15.1 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY23869.1 - 0.0046 16.9 0.0 0.0053 16.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CBY23869.1 - 0.025 14.9 0.0 0.04 14.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 CBY23869.1 - 0.053 13.7 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Amidohydro_2 PF04909.14 CBY23869.1 - 0.081 12.7 0.1 0.082 12.7 0.1 1.0 1 0 0 1 1 1 0 Amidohydrolase Thioredoxin_9 PF14595.6 CBY23869.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Mito_carr PF00153.27 CBY23870.1 - 1.9e-43 146.3 6.5 5.8e-18 64.6 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Biotin_carb_N PF00289.22 CBY23872.1 - 3.8e-32 111.1 0.0 5.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain ACC_central PF08326.12 CBY23873.1 - 2.1e-210 700.7 8.3 3.3e-210 700.1 8.3 1.3 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CBY23873.1 - 7.2e-136 453.7 0.0 1.1e-135 453.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CBY23873.1 - 1e-33 116.6 0.0 2e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 CBY23873.1 - 1.3e-22 79.9 0.0 4.3e-22 78.2 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBY23873.1 - 2.4e-09 36.9 0.3 6.6e-09 35.5 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBY23873.1 - 0.07 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like Apc13p PF05839.11 CBY23874.1 - 0.047 13.9 0.6 0.069 13.4 0.6 1.4 1 1 0 1 1 1 0 Apc13p protein Thiolase_N PF00108.23 CBY23875.1 - 4.2e-80 268.8 0.6 5.5e-80 268.5 0.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY23875.1 - 2.3e-47 159.7 4.8 5.6e-47 158.4 1.2 2.8 3 0 0 3 3 3 1 Thiolase, C-terminal domain Peptidase_M78 PF06114.13 CBY23875.1 - 0.031 14.2 0.2 0.74 9.7 0.3 2.5 2 1 1 3 3 3 0 IrrE N-terminal-like domain ketoacyl-synt PF00109.26 CBY23875.1 - 1.8 8.1 10.6 7.1 6.1 1.3 3.6 4 1 0 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain Cgr1 PF03879.14 CBY23876.1 - 0.39 11.1 29.6 0.75 10.2 29.7 1.5 1 1 0 1 1 1 0 Cgr1 family XRN_M PF17846.1 CBY23876.1 - 7.8 5.3 10.6 9.2 5.1 10.6 1.0 1 0 0 1 1 1 0 Xrn1 helical domain CCDC71L PF15374.6 CBY23876.1 - 8.2 5.6 16.6 8.5 5.5 16.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DHHC PF01529.20 CBY23877.1 - 0.062 13.4 0.6 0.077 13.1 0.6 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Thymidylate_kin PF02223.17 CBY23878.1 - 5.9e-44 149.9 0.0 7.5e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_14 PF13173.6 CBY23878.1 - 0.011 15.8 0.2 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain PPR_2 PF13041.6 CBY23878.1 - 0.014 15.5 0.0 6.1 7.1 0.0 2.7 2 1 0 2 2 2 0 PPR repeat family CPT PF07931.12 CBY23878.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PqqD PF05402.12 CBY23878.1 - 0.64 10.4 2.9 1.6 9.0 0.1 2.8 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) PseudoU_synth_2 PF00849.22 CBY23879.1 - 8.9e-31 107.1 0.9 1.5e-30 106.4 0.9 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_12 PF13424.6 CBY23880.1 - 1.7e-05 25.0 15.1 0.007 16.6 0.2 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY23880.1 - 0.0061 16.6 7.7 0.72 10.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat FANCI_S2 PF14676.6 CBY23880.1 - 0.11 12.7 2.0 0.29 11.4 2.0 1.7 1 1 0 1 1 1 0 FANCI solenoid 2 TPR_1 PF00515.28 CBY23880.1 - 1.8 8.5 11.7 4.2 7.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY23880.1 - 2.4 8.6 10.6 2.9 8.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Lyase_1 PF00206.20 CBY23881.1 - 7.5e-109 363.9 0.0 1.2e-108 363.3 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CBY23881.1 - 1.1e-20 73.7 0.1 7.3e-20 71.1 0.0 2.4 2 0 0 2 2 2 1 Fumarase C C-terminus HTH_Tnp_1 PF01527.20 CBY23881.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Transposase UQ_con PF00179.26 CBY23882.1 - 9.6e-54 180.8 0.0 1.1e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY23882.1 - 5.2e-05 23.5 0.0 8.5e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CBY23882.1 - 0.0074 16.0 0.0 0.0081 15.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBY23882.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Aida_N PF08910.10 CBY23884.1 - 0.0002 21.7 1.3 0.074 13.5 0.0 3.9 3 1 1 4 4 4 2 Aida N-terminus DUF2228 PF10228.9 CBY23885.1 - 2e-65 221.1 0.0 2.5e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) Transformer PF06495.11 CBY23885.1 - 1.9 8.5 23.6 3.8 7.6 23.6 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein Med4 PF10018.9 CBY23886.1 - 3.1e-18 66.2 2.4 3.1e-18 66.2 2.4 1.5 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 AAA_13 PF13166.6 CBY23886.1 - 0.11 11.2 4.8 0.13 10.9 4.8 1.1 1 0 0 1 1 1 0 AAA domain NifW PF03206.14 CBY23886.1 - 0.15 12.6 0.8 0.24 11.9 0.8 1.3 1 0 0 1 1 1 0 Nitrogen fixation protein NifW FB_lectin PF07367.11 CBY23886.1 - 0.17 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 Fungal fruit body lectin TGF_beta PF00019.20 CBY23887.1 - 4.2e-23 82.3 0.4 9.2e-22 78.0 0.4 2.3 1 1 0 1 1 1 1 Transforming growth factor beta like domain Skp1_POZ PF03931.15 CBY23887.1 - 0.038 14.2 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain SpvB PF03534.13 CBY23887.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein Nebulin PF00880.18 CBY23888.1 - 7.6e-50 166.3 192.4 4e-07 29.8 1.1 29.4 30 0 0 30 30 30 21 Nebulin repeat Scm3 PF10384.9 CBY23888.1 - 0.093 12.5 5.5 0.073 12.8 1.0 3.3 2 1 0 2 2 2 0 Centromere protein Scm3 fn3 PF00041.21 CBY23889.1 - 2e-19 69.7 3.1 1.6e-14 54.0 0.2 2.7 3 0 0 3 3 3 2 Fibronectin type III domain I-set PF07679.16 CBY23889.1 - 2.1e-09 37.3 6.1 3.7e-08 33.3 0.2 2.9 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY23889.1 - 1.9e-05 25.2 5.3 7.5e-05 23.3 0.7 3.2 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 CBY23889.1 - 9.8e-05 22.6 2.6 0.00018 21.7 0.2 2.6 2 1 1 3 3 3 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY23889.1 - 0.00027 21.5 15.1 0.0063 17.1 1.5 3.8 2 2 1 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CBY23889.1 - 0.0069 16.7 0.2 0.035 14.4 0.1 2.2 1 1 1 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.5 CBY23889.1 - 0.0075 16.6 2.3 0.015 15.6 0.6 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4959) fn3_2 PF16893.5 CBY23889.1 - 0.016 15.3 0.6 0.41 10.8 0.1 2.9 2 1 0 2 2 2 0 Fibronectin type III domain C2-set_2 PF08205.12 CBY23889.1 - 0.018 15.1 1.3 0.031 14.3 0.3 1.9 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain ig PF00047.25 CBY23889.1 - 0.061 13.5 3.9 0.14 12.4 0.7 2.8 2 0 0 2 2 2 0 Immunoglobulin domain Amnionless PF14828.6 CBY23889.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Amnionless Arylsulfotran_N PF17425.2 CBY23889.1 - 1.9 8.6 11.2 0.22 11.6 0.8 3.3 2 1 1 4 4 4 0 Arylsulfotransferase Ig-like domain Tgi2PP PF18250.1 CBY23890.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Effector immunity protein Tgi2PP Fib_alpha PF08702.10 CBY23890.1 - 7.6 6.7 9.5 2.2 8.4 0.5 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ald_Xan_dh_C2 PF02738.18 CBY23891.1 - 2.5e-173 577.5 0.0 3.5e-173 577.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 CBY23891.1 - 7.9e-31 105.9 0.1 1.9e-30 104.7 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 CBY23891.1 - 1.1e-26 93.5 0.0 2.8e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 CBY23891.1 - 3.8e-23 81.9 0.1 8.4e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 CBY23891.1 - 5.1e-20 71.6 0.1 2.7e-19 69.2 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 CBY23891.1 - 6.3e-08 32.5 0.2 6.3e-08 32.5 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Phospholip_A2_1 PF00068.19 CBY23892.1 - 4.8e-11 43.1 10.6 4.8e-11 43.1 10.6 2.2 2 0 0 2 2 2 1 Phospholipase A2 Astacin PF01400.24 CBY23894.1 - 1.8e-13 50.6 0.0 9.7e-12 44.9 0.0 2.4 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Lectin_C PF00059.21 CBY23894.1 - 0.014 16.1 1.4 0.043 14.5 1.4 1.9 1 0 0 1 1 1 0 Lectin C-type domain Ldl_recept_a PF00057.18 CBY23894.1 - 0.06 13.6 0.9 0.06 13.6 0.9 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A TPR_1 PF00515.28 CBY23895.1 - 1.6e-21 75.1 16.8 1.5e-06 27.7 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 CBY23895.1 - 8.2e-13 47.4 24.2 0.018 15.2 0.0 9.5 10 0 0 10 10 8 4 Tetratricopeptide repeat JmjC PF02373.22 CBY23895.1 - 1.6e-12 47.9 1.7 2.4e-12 47.3 0.3 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase TPR_11 PF13414.6 CBY23895.1 - 2.4e-09 36.7 0.1 0.0069 16.1 0.0 3.9 1 1 2 3 3 3 3 TPR repeat TPR_19 PF14559.6 CBY23895.1 - 3.5e-09 37.1 0.1 0.0073 16.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY23895.1 - 8.3e-09 36.0 0.0 0.0085 16.7 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY23895.1 - 9.5e-09 35.4 9.4 0.00031 21.0 0.0 5.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY23895.1 - 1.8e-07 31.1 0.1 0.14 12.6 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY23895.1 - 2.1e-07 30.6 15.0 0.24 11.7 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY23895.1 - 1.5e-05 25.4 0.8 1.2 10.2 0.0 4.4 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBY23895.1 - 0.00016 21.8 0.0 0.0016 18.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY23895.1 - 0.39 11.4 8.2 2e+02 2.9 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Branch PF02485.21 CBY23896.1 - 4.3e-50 170.5 0.0 5.5e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF5516 PF17637.2 CBY23896.1 - 0.091 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5516) Zona_pellucida PF00100.23 CBY23897.1 - 4.5e-34 118.4 0.7 5.3e-34 118.2 0.7 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain C2 PF00168.30 CBY23898.1 - 3.5e-50 168.6 0.0 5.5e-24 84.4 0.0 2.1 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CBY23898.1 - 0.0077 15.8 0.0 5.3 6.6 0.0 2.7 2 1 1 3 3 3 2 CEP76 C2 domain DnaI_N PF07319.11 CBY23898.1 - 0.056 14.1 0.0 0.2 12.4 0.1 1.8 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus PI3K_C2 PF00792.24 CBY23898.1 - 0.084 12.8 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Abhydrolase_2 PF02230.16 CBY23898.1 - 0.12 12.2 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase SelA PF03841.13 CBY23899.1 - 0.041 12.9 5.3 0.02 13.9 3.3 1.5 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase Nup54 PF13874.6 CBY23899.1 - 0.8 9.8 21.3 0.029 14.5 9.8 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Glutaredoxin2_C PF04399.13 CBY23900.1 - 0.057 13.3 0.6 0.17 11.7 0.4 1.8 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain DUF4230 PF14014.6 CBY23900.1 - 0.087 13.1 0.6 0.16 12.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DUF5345 PF17280.2 CBY23902.1 - 0.019 14.9 3.0 0.042 13.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF3810 PF12725.7 CBY23902.1 - 0.82 9.0 7.3 0.053 12.9 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) C8 PF08742.11 CBY23903.1 - 0.1 13.1 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 C8 domain Peptidase_M2 PF01401.18 CBY23906.1 - 1.6e-167 558.6 1.9 1.8e-167 558.4 1.9 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme DUF3439 PF11921.8 CBY23906.1 - 0.052 13.5 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) BRCT_2 PF16589.5 CBY23907.1 - 7.5e-12 45.5 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CBY23907.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Pkinase_Tyr PF07714.17 CBY23909.1 - 1.9e-55 187.9 0.0 1e-52 179.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY23909.1 - 4.9e-30 104.8 0.0 1.2e-29 103.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain MYEOV2 PF15004.6 CBY23909.1 - 0.057 13.9 0.6 1.4 9.4 1.1 2.9 2 0 0 2 2 2 0 Myeloma-overexpressed-like Pkinase_fungal PF17667.1 CBY23909.1 - 0.23 10.2 1.7 0.23 10.2 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase SAND PF01342.21 CBY23910.1 - 9.7e-16 57.3 0.4 9.7e-16 57.3 0.4 1.9 2 0 0 2 2 2 1 SAND domain zf-MYND PF01753.18 CBY23910.1 - 4.8e-06 26.6 17.3 4.8e-06 26.6 17.3 2.4 3 0 0 3 3 3 1 MYND finger CdvA PF18822.1 CBY23910.1 - 0.0011 18.8 0.3 0.0019 18.0 0.3 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain DUF4600 PF15372.6 CBY23910.1 - 0.11 12.9 3.6 1.1 9.7 3.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) DUF4407 PF14362.6 CBY23910.1 - 0.24 10.7 3.2 0.37 10.1 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dynactin_p62 PF05502.13 CBY23911.1 - 2.6e-27 95.8 7.0 2.4e-15 56.3 0.1 2.1 2 0 0 2 2 2 2 Dynactin p62 family Staphostatin_B PF09023.10 CBY23912.1 - 0.054 13.5 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Staphostatin B eIF-5_eIF-2B PF01873.17 CBY23913.1 - 4.8e-40 136.1 0.2 1e-39 135.0 0.2 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Antimicrobial_6 PF08036.11 CBY23913.1 - 0.033 14.2 0.5 0.065 13.3 0.5 1.4 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide UPF0561 PF10573.9 CBY23913.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 W2 PF02020.18 CBY23914.1 - 2.8e-17 62.6 3.5 5e-17 61.8 3.5 1.4 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3140 PF11338.8 CBY23914.1 - 0.043 14.2 1.5 0.071 13.5 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) Sugar_tr PF00083.24 CBY23915.1 - 1.9e-22 79.7 8.1 3.4e-22 78.9 8.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY23915.1 - 2.2e-19 69.6 14.3 1.6e-18 66.7 14.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CBY23915.1 - 4.2e-06 25.6 1.3 4.2e-06 25.6 1.3 1.7 2 0 0 2 2 2 1 MFS/sugar transport protein Branch PF02485.21 CBY23916.1 - 2.5e-48 164.8 0.6 3.2e-48 164.4 0.6 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Metallophos PF00149.28 CBY23917.1 - 1e-36 127.4 0.0 1.2e-36 127.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase La PF05383.17 CBY23918.1 - 1.6e-14 53.7 0.1 2.9e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 La domain SUZ-C PF12901.7 CBY23918.1 - 0.0003 20.7 0.0 0.0009 19.2 0.0 1.8 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.22 CBY23918.1 - 0.00053 19.8 0.1 0.004 16.9 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_Tyr PF07714.17 CBY23919.1 - 3e-07 30.0 0.0 7.7e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase HNOBA PF07701.14 CBY23919.1 - 8.8e-05 22.0 2.2 0.00013 21.5 2.2 1.3 1 0 0 1 1 1 1 Heme NO binding associated Pkinase PF00069.25 CBY23919.1 - 0.00015 21.2 0.0 0.00082 18.8 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Ion_trans_2 PF07885.16 CBY23921.1 - 2.8e-10 40.0 1.9 5e-10 39.2 1.9 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CBY23921.1 - 9.9e-09 34.8 0.7 1.5e-08 34.1 0.7 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY23921.1 - 5e-07 29.7 0.0 1.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CBY23921.1 - 0.036 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ion_trans PF00520.31 CBY23922.1 - 2.3e-15 56.5 3.0 2.9e-15 56.2 3.0 1.0 1 0 0 1 1 1 1 Ion transport protein DUF844 PF05815.11 CBY23922.1 - 0.1 11.8 0.2 0.15 11.3 0.2 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) DUF2228 PF10228.9 CBY23923.1 - 9.4e-56 189.3 0.0 9.4e-56 189.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2228) SEP PF08059.13 CBY23923.1 - 0.087 13.4 0.1 0.38 11.4 0.1 2.1 1 0 0 1 1 1 0 SEP domain Mad3_BUB1_I PF08311.12 CBY23924.1 - 3.8e-08 33.4 1.2 5.4e-08 32.9 1.2 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Kelch_4 PF13418.6 CBY23925.1 - 4.6e-14 52.2 0.3 0.00021 21.3 0.0 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY23925.1 - 2.9e-13 49.5 0.0 4.1e-06 26.7 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CBY23925.1 - 1.5e-12 47.5 0.2 0.0016 18.7 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY23925.1 - 1.1e-07 31.9 0.1 0.019 15.2 0.0 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CBY23925.1 - 3.3e-06 26.6 0.0 0.0025 17.4 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CBY23925.1 - 0.1 12.6 0.3 5.9 7.0 0.0 3.2 2 1 0 2 2 2 0 Kelch motif Jnk-SapK_ap_N PF09744.9 CBY23926.1 - 0.00065 19.9 5.0 0.00084 19.6 5.0 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.12 CBY23926.1 - 0.001 19.1 0.0 0.0014 18.7 0.0 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus HemX PF04375.14 CBY23926.1 - 0.0027 17.1 1.6 0.0035 16.7 1.6 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase FAM184 PF15665.5 CBY23926.1 - 0.0028 17.5 9.1 0.0036 17.1 9.1 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Baculo_p24 PF05073.12 CBY23926.1 - 0.004 17.0 0.9 0.0048 16.7 0.9 1.2 1 0 0 1 1 1 1 Baculovirus P24 capsid protein Serpin PF00079.20 CBY23926.1 - 0.0074 15.6 0.5 0.008 15.5 0.5 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) AI-2E_transport PF01594.16 CBY23926.1 - 0.014 14.6 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 AI-2E family transporter DUF4337 PF14235.6 CBY23926.1 - 0.028 14.5 0.6 0.036 14.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Atg14 PF10186.9 CBY23926.1 - 0.035 13.2 5.7 0.049 12.7 5.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3810 PF12725.7 CBY23926.1 - 0.038 13.3 0.2 0.048 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) SID-1_RNA_chan PF13965.6 CBY23926.1 - 0.071 11.5 1.1 0.082 11.3 1.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Prominin PF05478.11 CBY23926.1 - 0.1 10.5 3.6 0.13 10.2 3.6 1.2 1 0 0 1 1 1 0 Prominin Neur_chan_memb PF02932.16 CBY23926.1 - 0.23 11.5 0.9 0.38 10.8 0.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRF PF01765.19 CBY23926.1 - 0.26 11.3 9.2 4.7 7.1 9.0 2.2 2 1 0 2 2 2 0 Ribosome recycling factor LMBR1 PF04791.16 CBY23926.1 - 0.42 9.5 1.0 0.54 9.1 1.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2115 PF09888.9 CBY23926.1 - 0.76 10.3 6.0 1.7 9.2 6.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4446 PF14584.6 CBY23926.1 - 1.1 9.3 5.9 7.3 6.6 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF148 PF02520.17 CBY23926.1 - 1.5 9.0 9.1 3 8.0 8.8 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF4407 PF14362.6 CBY23926.1 - 2.5 7.4 4.8 1.5 8.1 3.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_2 PF12796.7 CBY23927.1 - 1.6e-07 31.8 0.5 4.4e-07 30.4 0.3 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY23927.1 - 2.6e-07 30.4 0.1 0.00083 19.6 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY23927.1 - 3.5e-06 27.2 0.1 0.00011 22.4 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 CBY23927.1 - 1e-05 26.2 0.0 0.0001 22.9 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Ank_4 PF13637.6 CBY23927.1 - 0.00027 21.4 0.0 0.0019 18.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY23927.1 - 0.003 17.9 0.2 0.13 12.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat MqsR_toxin PF15723.5 CBY23927.1 - 0.0043 17.4 0.4 15 6.0 0.0 3.6 3 0 0 3 3 3 1 Motility quorum-sensing regulator, toxin of MqsA Methyltransf_11 PF08241.12 CBY23927.1 - 0.0078 16.8 0.0 0.03 15.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain CI-B14_5a PF07347.12 CBY23928.1 - 1.2e-11 44.4 0.4 1.6e-11 44.0 0.4 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) TPR_12 PF13424.6 CBY23929.1 - 1.6e-15 57.1 10.0 6.1e-06 26.4 0.7 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY23929.1 - 1.2e-08 35.1 7.1 0.00049 20.3 0.2 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CBY23929.1 - 1.7e-08 33.9 17.3 0.28 11.4 0.1 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY23929.1 - 1.6e-06 27.6 15.1 0.0091 15.8 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY23929.1 - 1.2e-05 24.9 1.5 0.13 12.0 0.0 4.4 4 0 0 4 4 4 1 TPR repeat TPR_16 PF13432.6 CBY23929.1 - 3.2e-05 24.5 4.9 0.011 16.4 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY23929.1 - 9e-05 22.9 9.5 0.18 12.3 0.0 5.0 2 2 2 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.9 CBY23929.1 - 0.0003 20.5 9.8 0.00062 19.5 3.5 3.3 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 CBY23929.1 - 0.00042 20.9 5.6 19 6.4 0.1 6.1 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY23929.1 - 0.0011 18.8 8.8 0.51 10.5 0.1 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat ANTH PF07651.16 CBY23929.1 - 0.0049 15.9 3.8 0.026 13.5 0.2 2.3 2 0 0 2 2 2 1 ANTH domain TPR_MalT PF17874.1 CBY23929.1 - 0.011 15.2 2.4 0.045 13.1 2.7 1.7 2 0 0 2 2 2 0 MalT-like TPR region TPR_8 PF13181.6 CBY23929.1 - 0.014 15.6 13.3 3.4 8.1 0.2 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY23929.1 - 0.16 12.4 5.5 5.8 7.5 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBY23929.1 - 0.17 12.6 1.7 33 5.5 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 CBY23929.1 - 0.26 11.0 6.9 3.1 7.4 4.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CBY23929.1 - 0.84 9.6 12.6 0.39 10.6 0.5 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY23929.1 - 1.8 9.4 7.2 77 4.3 0.2 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat P4Ha_N PF08336.11 CBY23930.1 - 7.3e-26 90.8 2.9 7.3e-26 90.8 2.9 1.7 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CBY23930.1 - 5.2e-13 49.7 0.0 1.2e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_6 PF13174.6 CBY23930.1 - 0.095 13.4 0.6 0.61 10.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Exonuc_VII_L PF02601.15 CBY23930.1 - 7.6 6.0 6.8 5.4 6.5 3.4 2.2 2 1 0 3 3 3 0 Exonuclease VII, large subunit Na_Pi_cotrans PF02690.15 CBY23931.1 - 2.5e-32 111.9 27.1 2.6e-19 69.7 8.6 2.8 3 0 0 3 3 3 2 Na+/Pi-cotransporter zf-C2H2_4 PF13894.6 CBY23933.1 - 0.00053 20.6 8.7 0.18 12.7 2.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY23933.1 - 0.0013 19.1 7.8 0.25 11.9 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY23933.1 - 0.0053 17.1 9.6 0.15 12.6 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY23933.1 - 0.0087 16.4 0.9 0.0087 16.4 0.9 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Ribosomal_L37ae PF01780.19 CBY23933.1 - 0.012 15.7 1.7 0.29 11.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal L37ae protein family DUF2318 PF10080.9 CBY23933.1 - 0.038 14.1 0.2 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zinc_ribbon_4 PF13717.6 CBY23933.1 - 0.053 13.4 1.8 0.14 12.1 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 CBY23933.1 - 0.061 13.6 0.9 0.061 13.6 0.9 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY23933.1 - 0.092 13.1 4.5 1.1 9.7 0.8 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CBY23933.1 - 0.16 12.0 2.1 0.72 9.9 0.3 2.3 2 0 0 2 2 2 0 BED zinc finger LsmAD PF06741.13 CBY23938.1 - 0.0069 16.9 0.5 0.0097 16.4 0.5 1.4 1 1 0 1 1 1 1 LsmAD domain DUF3437 PF11919.8 CBY23938.1 - 0.027 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) AD PF09793.9 CBY23938.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Anticodon-binding domain Kelch_6 PF13964.6 CBY23939.1 - 2.4e-06 27.6 0.2 0.75 10.2 0.0 3.7 2 1 1 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CBY23939.1 - 0.074 13.1 0.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Astacin PF01400.24 CBY23940.1 - 7.3e-32 110.5 0.2 3.7e-31 108.2 0.1 2.1 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY23940.1 - 0.0017 18.6 3.9 0.0017 18.6 3.9 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Peptidase_M10 PF00413.24 CBY23940.1 - 0.069 13.0 0.2 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 Matrixin DUF45 PF01863.17 CBY23940.1 - 0.34 10.9 1.2 0.55 10.2 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 PRKCSH-like PF12999.7 CBY23940.1 - 1.3 8.8 5.8 3.7 7.3 5.8 1.8 1 1 0 1 1 1 0 Glucosidase II beta subunit-like MAD PF05557.13 CBY23943.1 - 3.7e-07 28.9 4.0 1.3e-06 27.1 4.0 1.7 1 1 0 1 1 1 1 Mitotic checkpoint protein GIT_CC PF16559.5 CBY23943.1 - 0.085 12.7 0.2 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2399 PF09664.10 CBY23943.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) adh_short PF00106.25 CBY23944.1 - 4.9e-45 153.4 0.4 6.7e-45 152.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY23944.1 - 3.3e-43 147.9 0.5 5.1e-43 147.3 0.5 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY23944.1 - 1.2e-08 35.1 2.7 2.8e-07 30.6 2.7 2.3 1 1 0 1 1 1 1 KR domain PALP PF00291.25 CBY23944.1 - 0.0019 17.7 0.7 0.003 17.0 0.2 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 CBY23944.1 - 0.0063 16.0 0.1 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rgp1 PF08737.10 CBY23945.1 - 7.1e-19 68.3 0.4 2.9e-15 56.4 0.1 2.5 2 1 1 3 3 3 2 Rgp1 Arrestin_N PF00339.29 CBY23945.1 - 0.0007 19.7 0.4 0.0021 18.1 0.4 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain GAS PF13851.6 CBY23946.1 - 4.6e-75 251.4 37.3 4.6e-75 251.4 37.3 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 CBY23946.1 - 0.66 10.0 18.0 2 8.4 4.5 4.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Clathrin PF00637.20 CBY23947.1 - 9.7e-17 61.2 3.3 2e-16 60.2 0.7 2.7 2 1 0 2 2 2 1 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CBY23947.1 - 0.0062 16.8 0.4 0.33 11.3 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Vps39_2 PF10367.9 CBY23947.1 - 0.012 16.1 0.1 0.032 14.7 0.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 GUN4_N PF16416.5 CBY23947.1 - 0.045 13.7 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal PHD_Oberon PF07227.11 CBY23947.1 - 0.46 10.4 13.5 0.072 13.0 5.1 3.1 3 0 0 3 3 3 0 PHD - plant homeodomain finger protein WD40 PF00400.32 CBY23947.1 - 1 10.3 3.1 3.7 8.6 0.1 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat Acyltransferase PF01553.21 CBY23948.1 - 2e-10 40.4 0.0 1e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 CBY23948.1 - 3.4e-10 39.9 0.0 7.6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus EamA PF00892.20 CBY23949.1 - 0.0086 16.2 6.4 0.14 12.4 2.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family DUF3955 PF13127.6 CBY23949.1 - 0.025 14.4 0.6 0.025 14.4 0.6 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3955) DUF5453 PF17534.2 CBY23949.1 - 0.16 11.9 4.7 0.48 10.3 4.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5453) SdpI PF13630.6 CBY23949.1 - 1.3 9.2 4.0 20 5.4 0.1 2.5 2 0 0 2 2 2 0 SdpI/YhfL protein family Pox_A14 PF05767.12 CBY23949.1 - 2.3 8.4 9.3 1.7 8.8 0.3 3.4 2 2 0 3 3 3 0 Poxvirus virion envelope protein A14 EamA PF00892.20 CBY23950.1 - 0.6 10.3 13.8 0.84 9.8 13.8 1.2 1 0 0 1 1 1 0 EamA-like transporter family DUF3302 PF11742.8 CBY23950.1 - 6 7.1 7.7 21 5.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) PBP_N PF17093.5 CBY23951.1 - 6.2 7.1 9.7 0.16 12.2 1.6 2.5 2 1 1 3 3 3 0 Penicillin-binding protein N-terminus Pkinase PF00069.25 CBY23952.1 - 4.5e-59 200.0 0.6 9e-59 199.0 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY23952.1 - 8.4e-32 110.5 0.2 1.4e-29 103.2 0.2 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY23952.1 - 3.7e-06 26.5 3.3 0.0013 18.1 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Pkinase_C PF00433.24 CBY23952.1 - 0.00019 22.0 2.1 0.00037 21.1 2.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 CBY23952.1 - 0.0018 18.3 0.4 0.054 13.4 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY23952.1 - 0.0034 16.4 0.1 0.0046 16.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY23952.1 - 0.024 13.4 0.3 0.1 11.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase S-AdoMet_synt_C PF02773.16 CBY23952.1 - 0.047 13.7 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain FTA2 PF13095.6 CBY23952.1 - 0.08 12.6 0.2 11 5.5 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PEPCK_GTP PF00821.18 CBY23953.1 - 2.7e-163 543.0 1.7 3.3e-163 542.7 1.7 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 CBY23953.1 - 1.1e-93 312.8 0.0 1.7e-93 312.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Lipocalin_2 PF08212.12 CBY23954.1 - 8.3e-18 64.7 0.6 1.2e-17 64.2 0.6 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY23954.1 - 8.3e-05 22.8 0.1 0.00032 20.9 0.1 1.9 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 CBY23954.1 - 0.0046 16.8 1.6 0.023 14.5 1.6 2.0 1 1 0 1 1 1 1 Triabin NADH_dh_m_C1 PF15088.6 CBY23954.1 - 0.14 11.8 0.4 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DnaJ PF00226.31 CBY23955.1 - 2.7e-05 24.2 0.0 0.00041 20.4 0.0 2.3 1 1 0 1 1 1 1 DnaJ domain Tubulin PF00091.25 CBY23956.1 - 1.8e-68 230.7 0.0 2.2e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY23956.1 - 1.1e-09 38.5 0.0 2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY23956.1 - 0.0012 18.5 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF5610 PF18433.1 CBY23957.1 - 0.02 15.4 0.0 0.029 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) EzrA PF06160.12 CBY23957.1 - 0.025 12.8 0.0 0.027 12.6 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Triabin PF03973.13 CBY23958.1 - 0.061 13.2 1.6 0.43 10.4 0.1 2.1 1 1 1 2 2 2 0 Triabin TSP_1 PF00090.19 CBY23959.1 - 1.8e-11 44.0 33.6 7.8e-09 35.6 8.0 4.8 5 0 0 5 5 5 2 Thrombospondin type 1 domain Ephrin_rec_like PF07699.13 CBY23959.1 - 3.4e-09 36.3 10.7 3.8e-06 26.6 6.0 3.4 1 1 1 2 2 2 2 Putative ephrin-receptor like Peptidase_S49_N PF08496.10 CBY23959.1 - 3.6 7.6 4.6 1 9.4 1.4 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AF-4 PF05110.13 CBY23960.1 - 2.4 6.2 34.1 2.5 6.1 34.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HEAT_2 PF13646.6 CBY23961.1 - 0.0036 17.7 0.1 0.22 12.0 0.0 3.9 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 CBY23961.1 - 0.023 14.9 0.4 16 6.1 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat DUF5539 PF17693.1 CBY23961.1 - 0.72 9.5 3.0 1.2 8.7 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) PAS_11 PF14598.6 CBY23962.1 - 5.1e-10 39.5 0.3 1.2e-09 38.3 0.3 1.6 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 CBY23962.1 - 2.9e-09 37.1 0.1 6.5e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CBY23962.1 - 0.0018 18.2 0.1 0.51 10.4 0.1 2.5 2 0 0 2 2 2 2 PAS fold DDRGK PF09756.9 CBY23962.1 - 0.029 14.0 0.9 0.054 13.1 0.9 1.4 1 0 0 1 1 1 0 DDRGK domain HLH PF00010.26 CBY23962.1 - 0.054 13.5 2.3 0.1 12.6 2.3 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain ADP_PFK_GK PF04587.15 CBY23963.1 - 3.8e-128 427.7 0.0 4.5e-128 427.5 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region DEAD PF00270.29 CBY23964.1 - 5.2e-55 185.9 0.0 7.7e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY23964.1 - 1.1e-27 96.5 0.0 2.6e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 CBY23964.1 - 8.1e-18 64.7 0.1 1.9e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 SPRY domain ResIII PF04851.15 CBY23964.1 - 0.0077 16.2 0.0 0.67 9.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBY23964.1 - 0.0089 15.4 2.3 0.011 15.0 0.1 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Neuralized PF07177.12 CBY23964.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Neuralized Trefoil PF00088.18 CBY23966.1 - 1.3e-10 40.9 9.4 1.3e-10 40.9 9.4 2.6 2 1 0 2 2 2 1 Trefoil (P-type) domain Amnionless PF14828.6 CBY23966.1 - 0.0028 16.6 0.0 0.0028 16.6 0.0 1.7 2 0 0 2 2 2 1 Amnionless Podoplanin PF05808.11 CBY23966.1 - 0.0034 17.5 0.0 0.0074 16.4 0.0 1.5 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.6 CBY23966.1 - 0.059 13.4 0.1 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Lectin_C PF00059.21 CBY23967.1 - 1.1e-64 215.9 28.1 7e-17 62.1 0.2 6.6 6 0 0 6 6 6 5 Lectin C-type domain F5_F8_type_C PF00754.25 CBY23967.1 - 3.6e-24 85.3 0.6 1.4e-17 64.0 0.1 3.5 3 0 0 3 3 3 2 F5/8 type C domain LCCL PF03815.19 CBY23967.1 - 5.3e-16 58.5 0.8 1.6e-15 57.0 0.8 1.8 1 0 0 1 1 1 1 LCCL domain fn2 PF00040.19 CBY23967.1 - 4.6e-06 26.8 4.4 2.7e-05 24.4 4.4 2.5 1 0 0 1 1 1 1 Fibronectin type II domain ABC2_membrane PF01061.24 CBY23968.1 - 2.1e-40 138.4 24.7 3.1e-40 137.8 24.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBY23968.1 - 4.2e-22 79.1 0.1 6.8e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 CBY23968.1 - 1.4e-05 24.9 1.3 8.6e-05 22.4 0.1 2.6 2 0 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 CBY23968.1 - 5.4e-05 23.1 0.2 0.00014 21.8 0.2 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 CBY23968.1 - 0.00021 20.5 23.3 0.00037 19.7 20.0 2.2 1 1 0 2 2 2 1 ABC-2 family transporter protein Dynamin_N PF00350.23 CBY23968.1 - 0.00062 19.9 0.4 0.0038 17.3 0.4 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBY23968.1 - 0.00095 19.2 1.0 0.0031 17.6 0.3 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY23968.1 - 0.0012 19.2 0.1 0.0064 16.8 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.6 CBY23968.1 - 0.0017 18.3 0.6 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBY23968.1 - 0.0062 16.2 1.9 0.02 14.6 1.1 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 CBY23968.1 - 0.012 15.7 0.3 0.026 14.6 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 CBY23968.1 - 0.013 14.9 0.4 0.1 12.1 0.3 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY23968.1 - 0.017 15.5 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 CBY23968.1 - 0.044 12.8 0.1 0.091 11.7 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IIGP PF05049.13 CBY23968.1 - 0.048 12.7 0.1 0.083 11.9 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_30 PF13604.6 CBY23968.1 - 0.064 13.0 0.0 0.15 11.7 0.1 1.6 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 CBY23968.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY23968.1 - 0.079 13.4 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Septin PF00735.18 CBY23968.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin PRK PF00485.18 CBY23968.1 - 0.082 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CBY23968.1 - 0.1 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3392 PF11872.8 CBY23968.1 - 0.32 11.3 6.6 0.12 12.6 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3392) Glyco_transf_10 PF00852.19 CBY23969.1 - 2.1e-39 135.1 0.3 2.1e-39 135.1 0.3 2.0 2 1 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY23969.1 - 7.1e-15 55.4 0.2 1.6e-14 54.3 0.2 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Leader_CPA1 PF08252.11 CBY23969.1 - 0.089 12.2 0.8 0.34 10.3 0.8 2.0 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide Ldh_1_C PF02866.18 CBY23970.1 - 4.1e-44 150.5 0.0 1.4e-43 148.7 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CBY23970.1 - 8.1e-39 132.9 1.7 1.4e-38 132.1 1.7 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CBY23970.1 - 1.8e-05 23.9 0.1 2.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CBY23970.1 - 0.0034 17.3 2.5 0.013 15.4 0.2 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CBY23970.1 - 0.013 15.7 0.1 0.038 14.3 0.1 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 CBY23970.1 - 0.057 12.7 6.8 0.078 12.3 0.9 3.0 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 CBY23970.1 - 0.064 13.4 1.6 0.22 11.6 0.1 2.6 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 CBY23970.1 - 0.095 12.1 0.1 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CBY23970.1 - 0.11 12.9 0.8 0.36 11.3 0.1 2.2 2 2 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PROCN PF08083.11 CBY23972.1 - 4.8e-228 756.7 7.6 4.8e-228 756.7 7.6 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CBY23972.1 - 1.6e-126 420.5 0.3 3.1e-126 419.6 0.3 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CBY23972.1 - 5.6e-89 296.1 2.3 1.4e-88 294.8 2.3 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CBY23972.1 - 4.6e-87 289.6 5.5 7.2e-87 289.0 4.4 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CBY23972.1 - 5.7e-72 240.1 0.0 1.2e-71 239.0 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 CBY23972.1 - 4.5e-52 175.1 0.0 1.3e-51 173.7 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 CBY23972.1 - 3.9e-46 155.3 0.6 1.2e-45 153.8 0.6 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 CBY23972.1 - 4.7e-11 42.7 0.0 2.3e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CR6_interact PF10147.9 CBY23972.1 - 0.028 14.1 1.8 0.047 13.4 0.3 2.1 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF775 PF05603.12 CBY23972.1 - 0.31 10.5 1.6 0.82 9.2 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF775) FAM163 PF15069.6 CBY23974.1 - 0.00053 20.5 2.1 0.00063 20.2 1.6 1.5 1 1 0 1 1 1 1 FAM163 family Prominin PF05478.11 CBY23974.1 - 0.046 11.7 1.7 0.059 11.3 1.7 1.1 1 0 0 1 1 1 0 Prominin RCC1 PF00415.18 CBY23976.1 - 1e-22 80.5 0.1 9.5e-09 35.8 0.1 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CBY23976.1 - 1.6e-17 63.7 0.0 4.2e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain RCC1_2 PF13540.6 CBY23976.1 - 2.8e-11 42.9 7.3 1e-05 25.2 0.3 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 CBY23976.1 - 0.014 16.0 0.0 0.044 14.4 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Stathmin PF00836.19 CBY23976.1 - 0.034 14.1 0.7 0.034 14.1 0.7 2.3 2 0 0 2 2 2 0 Stathmin family Vault PF01505.18 CBY23976.1 - 0.15 12.3 0.1 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Major Vault Protein repeat domain RhoGAP PF00620.27 CBY23977.1 - 6.9e-17 61.7 0.0 1.2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CBY23977.1 - 1.2e-09 38.0 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PapD-like PF14874.6 CBY23977.1 - 0.091 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like DUF1573 PF07610.11 CBY23977.1 - 0.094 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) Condensation PF00668.20 CBY23979.1 - 0.00028 19.7 0.1 0.0046 15.7 0.1 2.6 1 1 0 1 1 1 1 Condensation domain Tubulin PF00091.25 CBY23980.1 - 2.1e-67 227.2 0.0 2.7e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY23980.1 - 1.9e-51 173.5 0.0 3e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY23980.1 - 0.0017 18.0 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain TMEM154 PF15102.6 CBY23981.1 - 0.0069 16.3 0.2 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 CBY23981.1 - 0.034 15.0 0.0 0.087 13.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PspB PF06667.12 CBY23981.1 - 0.097 12.7 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 Phage shock protein B DUF621 PF04789.15 CBY23981.1 - 0.44 9.7 1.5 0.72 9.0 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) INPP5B_PH PF16776.5 CBY23982.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain DUF4562 PF15123.6 CBY23983.1 - 9.8e-10 38.4 0.0 9.5e-09 35.2 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4562) PPL5 PF18168.1 CBY23985.1 - 0.85 8.9 5.7 0.95 8.7 5.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Sec62 PF03839.16 CBY23985.1 - 1.2 8.6 6.4 1.4 8.3 6.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Med24_N PF11277.8 CBY23985.1 - 8.5 4.3 7.9 9.3 4.1 7.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Ammonium_transp PF00909.21 CBY23986.1 - 2.3e-82 276.8 18.9 2.1e-52 178.2 13.1 2.1 2 0 0 2 2 2 2 Ammonium Transporter Family PH PF00169.29 CBY23989.1 - 1.3e-06 28.8 1.2 3.7e-06 27.4 1.1 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 CBY23989.1 - 0.00073 19.9 0.4 0.0078 16.6 0.4 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBY23989.1 - 0.0044 17.4 0.4 0.0044 17.4 0.4 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PTH2 PF01981.16 CBY23989.1 - 3.6 7.9 10.4 0.68 10.2 4.8 2.5 2 1 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 Collagen PF01391.18 CBY23990.1 - 4.5e-18 64.8 62.3 1.5e-08 34.3 18.9 3.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY23990.1 - 3.6e-14 53.4 0.5 2.2e-13 50.8 0.3 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY23990.1 - 0.0064 17.1 0.2 0.026 15.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain ERAP1_C PF11838.8 CBY23990.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain FWWh PF14922.6 CBY23991.1 - 2.4e-35 121.6 0.6 4.5e-35 120.7 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function HisKA PF00512.25 CBY23991.1 - 0.088 12.9 0.1 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain HU-DNA_bdg PF14848.6 CBY23991.1 - 1.3 9.1 5.0 22 5.1 0.2 3.1 3 0 0 3 3 3 0 DNA-binding domain TSP_1 PF00090.19 CBY23992.1 - 0.00073 19.7 3.4 0.00073 19.7 3.4 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain VWD PF00094.25 CBY23993.1 - 1.4e-84 282.2 35.7 9.8e-15 55.2 2.4 6.4 6 0 0 6 6 6 6 von Willebrand factor type D domain C8 PF08742.11 CBY23993.1 - 1.8e-42 143.6 84.4 1.2e-09 38.5 3.7 10.7 8 1 1 9 9 9 6 C8 domain TIL PF01826.17 CBY23993.1 - 2e-14 53.6 69.9 1.3e-06 28.5 11.2 14.7 13 2 0 13 13 13 6 Trypsin Inhibitor like cysteine rich domain Carn_acyltransf PF00755.20 CBY23994.1 - 6.5e-189 629.3 0.0 7.5e-189 629.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 CBY23994.1 - 4.8e-24 84.1 0.1 1e-23 83.1 0.1 1.6 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus WW PF00397.26 CBY23995.1 - 8.7e-08 32.1 1.9 8.7e-08 32.1 1.9 2.0 2 0 0 2 2 2 1 WW domain Cgr1 PF03879.14 CBY23995.1 - 0.12 12.8 0.3 0.12 12.8 0.3 4.7 4 1 1 5 5 5 0 Cgr1 family Pentapeptide PF00805.22 CBY23996.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.5 1 1 0 1 1 1 0 Pentapeptide repeats (8 copies) Ribosomal_L28 PF00830.19 CBY23997.1 - 0.056 13.6 0.7 0.15 12.2 0.7 1.7 1 0 0 1 1 1 0 Ribosomal L28 family DUF737 PF05300.11 CBY23998.1 - 0.00024 21.5 2.2 0.00026 21.4 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF737) E1-E2_ATPase PF00122.20 CBY23999.1 - 3.9e-36 124.2 1.0 3.2e-35 121.3 0.1 2.8 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 CBY23999.1 - 3.7e-15 56.1 0.8 2.1e-14 53.7 0.8 2.4 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 CBY23999.1 - 3.4e-12 47.1 0.0 1.2e-08 35.5 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY23999.1 - 3.1e-06 27.2 0.0 6.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 CBY23999.1 - 0.0015 18.3 2.6 0.0015 18.3 2.6 3.2 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 CBY23999.1 - 0.056 13.1 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus ASH PF15780.5 CBY24000.1 - 5.3e-19 68.2 3.5 1.2e-07 31.8 0.0 5.5 5 0 0 5 5 5 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CBY24000.1 - 6.1e-06 26.4 5.8 0.08 13.2 0.0 4.3 5 0 0 5 5 5 3 Transmembrane protein 131-like Motile_Sperm PF00635.26 CBY24000.1 - 1.4e-05 24.9 0.3 0.09 12.6 0.0 4.2 3 0 0 3 3 3 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBY24000.1 - 0.0022 18.0 0.3 5 7.2 0.0 4.9 4 1 0 4 4 4 1 Protein of unknown function (DUF1573) SPRY PF00622.28 CBY24001.1 - 5.5e-15 55.5 1.5 1.4e-06 28.5 0.1 2.4 2 0 0 2 2 2 2 SPRY domain CcmH PF03918.14 CBY24003.1 - 0.003 16.8 0.0 0.0036 16.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein EphA2_TM PF14575.6 CBY24003.1 - 0.0089 16.9 0.0 0.012 16.5 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 CBY24003.1 - 0.018 13.8 0.0 0.022 13.5 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF5305 PF17231.2 CBY24003.1 - 0.024 14.0 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 CBY24003.1 - 0.069 11.9 0.0 0.072 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 CBY24003.1 - 0.11 12.3 0.4 0.18 11.6 0.3 1.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 CBY24003.1 - 0.13 12.5 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TM_helix PF05552.12 CBY24003.1 - 4.1 7.4 8.1 7.5 6.6 8.1 1.4 1 0 0 1 1 1 0 Conserved TM helix zf-H2C2_2 PF13465.6 CBY24004.1 - 0.18 12.3 28.8 0.097 13.1 2.4 5.3 5 0 0 5 5 5 0 Zinc-finger double domain HSP70 PF00012.20 CBY24005.1 - 6.8e-253 840.3 11.0 7.8e-253 840.1 11.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBY24005.1 - 6.2e-15 54.8 0.8 1.7e-13 50.1 0.2 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CBY24005.1 - 0.0014 19.0 6.5 0.3 11.5 0.2 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 CBY24005.1 - 0.015 14.6 0.6 0.015 14.6 0.6 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 CBY24005.1 - 0.023 13.9 0.1 0.058 12.6 0.1 1.7 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.16 CBY24005.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Pex19 PF04614.12 CBY24005.1 - 2.7 7.7 11.0 0.4 10.4 5.3 2.1 2 0 0 2 2 2 0 Pex19 protein family HSP70 PF00012.20 CBY24006.1 - 6.5e-221 734.7 9.6 6.6e-192 638.9 6.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CBY24006.1 - 4.1e-18 65.3 0.3 2.1e-17 63.0 0.3 2.0 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 CBY24006.1 - 0.00036 20.3 0.0 0.0016 18.2 0.0 2.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CBY24006.1 - 0.011 16.2 1.2 4.7 7.7 0.2 3.7 3 2 0 3 3 3 0 Cell division protein FtsA DUF4484 PF14831.6 CBY24006.1 - 0.017 15.2 0.8 0.032 14.3 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DDR PF08841.10 CBY24006.1 - 0.026 13.5 7.5 0.11 11.5 0.1 3.4 3 1 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CBY24006.1 - 0.49 9.6 3.3 2.1 7.5 0.1 2.6 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase mTERF PF02536.14 CBY24007.1 - 0.0018 17.2 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 mTERF XAP5 PF04921.14 CBY24008.1 - 1.9e-63 214.6 20.8 1.9e-63 214.6 20.8 1.6 1 1 1 2 2 2 1 XAP5, circadian clock regulator DDHD PF02862.17 CBY24008.1 - 0.096 12.8 2.4 0.16 12.1 2.4 1.3 1 0 0 1 1 1 0 DDHD domain Arfaptin PF06456.13 CBY24009.1 - 3.3e-46 157.7 10.5 4.6e-46 157.2 10.5 1.1 1 0 0 1 1 1 1 Arfaptin-like domain COOH-NH2_lig PF14395.6 CBY24009.1 - 0.11 11.7 1.3 0.31 10.2 0.1 2.2 2 1 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 Occludin_ELL PF07303.13 CBY24009.1 - 0.34 11.7 4.5 1.9 9.2 0.1 2.7 2 0 0 2 2 2 0 Occludin homology domain APG6_N PF17675.1 CBY24009.1 - 1.2 9.6 8.8 0.68 10.5 3.3 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 CBY24009.1 - 6 7.2 7.5 2.8 8.3 0.3 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UQ_con PF00179.26 CBY24010.1 - 3e-42 143.6 0.0 3.6e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kelch_3 PF13415.6 CBY24011.1 - 3.4e-08 33.6 0.7 0.004 17.4 0.1 4.6 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY24011.1 - 4.5e-08 32.7 3.0 4.8e-07 29.5 0.1 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY24011.1 - 8.1e-08 32.3 0.5 7e-06 26.2 0.1 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 CBY24011.1 - 1.5e-07 31.3 3.3 8.2e-05 22.5 0.1 4.7 4 1 1 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY24011.1 - 3.3e-07 29.8 0.1 8.2e-07 28.5 0.1 1.7 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.6 CBY24011.1 - 2.2e-06 27.5 0.0 0.00058 19.8 0.1 3.3 3 0 0 3 3 3 1 Kelch motif F-box-like PF12937.7 CBY24011.1 - 3.2e-05 23.7 0.0 0.0012 18.7 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CBY24011.1 - 0.0013 18.6 0.2 0.0063 16.4 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CBY24011.1 - 0.014 15.2 0.0 0.056 13.3 0.0 1.9 2 0 0 2 2 2 0 F-box UL17 PF17640.2 CBY24011.1 - 0.087 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized UL17 Pkinase PF00069.25 CBY24013.1 - 2.4e-32 112.4 0.0 5e-32 111.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CBY24013.1 - 1.5e-08 34.3 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CBY24013.1 - 4.7e-08 32.6 0.0 6.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY24013.1 - 0.00014 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY24013.1 - 0.0019 17.9 0.1 0.0036 16.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CBY24013.1 - 0.0026 17.1 0.0 0.0093 15.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBY24013.1 - 0.0044 15.9 0.1 0.0066 15.3 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY24013.1 - 0.013 14.4 0.4 0.65 8.9 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain CUB PF00431.20 CBY24014.1 - 1.1e-54 183.5 1.0 8.8e-21 74.3 0.0 3.2 3 0 0 3 3 3 3 CUB domain NTR PF01759.21 CBY24014.1 - 0.00018 21.3 0.1 0.00034 20.4 0.1 1.4 1 0 0 1 1 1 1 UNC-6/NTR/C345C module PRIMA1 PF16101.5 CBY24015.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FAA_hydrolase PF01557.18 CBY24016.1 - 6.4e-55 186.2 0.0 8.6e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 CBY24016.1 - 5.2e-29 100.6 0.0 9.7e-29 99.7 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fibrillarin PF01269.17 CBY24017.1 - 1.9e-106 354.3 0.0 2.3e-106 354.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CBY24017.1 - 6.9e-05 22.6 0.1 9.9e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 CBY24017.1 - 0.015 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 CBY24017.1 - 0.055 13.2 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 CBY24017.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DEAD PF00270.29 CBY24018.1 - 6.8e-43 146.5 0.3 1.1e-42 145.8 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY24018.1 - 9.8e-33 112.8 0.0 4.9e-31 107.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY24018.1 - 4e-06 26.9 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBY24018.1 - 8.2e-05 23.0 0.3 0.0009 19.6 0.4 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBY24018.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 CBY24018.1 - 0.00019 20.3 0.0 0.04 12.7 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 CBY24018.1 - 0.048 12.9 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Helicase_RecD PF05127.14 CBY24018.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 CBY24018.1 - 0.12 12.4 0.3 0.46 10.4 0.1 2.2 2 1 0 2 2 2 0 Flavivirus DEAD domain DUF1833 PF08875.11 CBY24018.1 - 0.12 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) PhoH PF02562.16 CBY24018.1 - 0.15 11.5 1.5 0.33 10.4 0.3 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 CBY24018.1 - 0.15 12.3 1.1 1.3 9.3 1.1 2.3 1 1 0 1 1 1 0 AAA domain ubiquitin PF00240.23 CBY24019.1 - 6.3e-07 29.0 0.2 1.9e-06 27.5 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CBY24019.1 - 0.00069 20.0 0.2 0.0044 17.4 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CBY24019.1 - 0.0041 16.9 0.2 0.0087 15.9 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBY24019.1 - 0.022 14.8 0.2 0.51 10.4 0.2 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain PI3K_rbd PF00794.18 CBY24019.1 - 0.031 14.4 0.0 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain DUF92 PF01940.16 CBY24020.1 - 3.3e-57 193.6 5.3 3.3e-28 98.7 0.5 2.1 2 0 0 2 2 2 2 Integral membrane protein DUF92 TMEM132D_C PF15706.5 CBY24020.1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF2207 PF09972.9 CBY24020.1 - 0.11 11.2 2.1 0.33 9.7 2.1 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Band_7 PF01145.25 CBY24021.1 - 1.1e-24 87.5 0.5 1.4e-24 87.1 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.25 CBY24022.1 - 1.3e-60 205.0 0.1 1.6e-60 204.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24022.1 - 1.7e-39 135.7 0.0 2e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY24022.1 - 2.3e-06 26.7 0.0 4.2e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY24022.1 - 7.9e-05 22.1 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY24022.1 - 0.00022 20.6 0.3 0.00049 19.5 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY24022.1 - 0.037 14.0 0.0 0.12 12.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M1 PF01433.20 CBY24023.1 - 7.8e-41 140.0 1.3 7.8e-41 140.0 1.3 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CBY24023.1 - 1.2e-40 140.0 5.0 1.8e-40 139.4 5.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CBY24023.1 - 3.2e-32 112.2 0.0 5.6e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Mpv17_PMP22 PF04117.12 CBY24024.1 - 5.7e-11 42.5 1.9 1.1e-10 41.6 1.9 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family PTPS_related PF10131.9 CBY24024.1 - 0.0066 14.8 0.8 0.0082 14.5 0.8 1.1 1 0 0 1 1 1 1 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Yippee-Mis18 PF03226.14 CBY24025.1 - 5.7e-07 29.7 1.4 8e-07 29.2 1.3 1.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly XPG_I PF00867.18 CBY24027.1 - 1.3e-19 70.3 0.1 3.5e-19 68.9 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CBY24027.1 - 1e-16 61.2 0.0 2.2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CBY24027.1 - 9.1e-06 25.3 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing BAH PF01426.18 CBY24027.1 - 0.034 14.0 0.7 0.48 10.3 0.6 2.5 1 1 0 1 1 1 0 BAH domain CBM39 PF15886.5 CBY24027.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Pkinase PF00069.25 CBY24028.1 - 3e-67 226.8 0.0 5.4e-67 225.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24028.1 - 1.1e-43 149.4 0.0 1.7e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY24028.1 - 9.2e-07 28.5 0.4 5.3e-06 26.0 0.4 2.3 1 1 0 1 1 1 1 Kinase-like PBD PF00786.28 CBY24028.1 - 1.1e-05 25.6 2.0 4.4e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 P21-Rho-binding domain APH PF01636.23 CBY24028.1 - 0.0025 17.8 0.0 0.34 10.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY24028.1 - 0.014 14.2 7.3 0.14 10.9 7.4 2.3 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBY24028.1 - 0.085 12.2 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM163 PF15069.6 CBY24028.1 - 0.2 12.1 2.2 0.21 12.0 0.6 1.8 1 1 1 2 2 2 0 FAM163 family PCI PF01399.27 CBY24029.1 - 4.3e-09 36.8 0.4 4.3e-09 36.8 0.4 3.3 4 0 0 4 4 4 1 PCI domain MtrG PF04210.13 CBY24029.1 - 2.9 7.8 4.5 2.2 8.2 1.0 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G ALMT PF11744.8 CBY24030.1 - 8.6 5.1 8.6 10 4.8 8.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase PF00069.25 CBY24031.1 - 2.2e-41 142.0 0.0 6e-41 140.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24031.1 - 2.9e-24 85.7 0.0 6.5e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 CBY24031.1 - 7.8e-05 22.7 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain APH PF01636.23 CBY24031.1 - 0.047 13.6 0.0 13 5.6 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Binary_toxB PF03495.14 CBY24031.1 - 1.7 8.9 3.6 1.2e+02 3.0 0.0 3.5 3 0 0 3 3 3 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Ras PF00071.22 CBY24032.1 - 5e-49 166.0 0.0 5.8e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY24032.1 - 2.3e-30 105.3 0.0 4.5e-30 104.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY24032.1 - 3.1e-10 39.8 0.0 4.2e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY24032.1 - 0.00015 21.8 0.0 0.00028 21.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBY24032.1 - 0.00018 21.8 0.1 0.00092 19.6 0.1 2.0 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CBY24032.1 - 0.0035 17.1 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CBY24032.1 - 0.0044 16.4 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY24032.1 - 0.0077 15.8 0.2 0.029 13.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgoMid PF16487.5 CBY24032.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute G-alpha PF00503.20 CBY24032.1 - 0.016 14.4 1.0 1.7 7.8 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 CBY24032.1 - 0.026 14.4 0.1 0.72 9.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DAP3 PF10236.9 CBY24032.1 - 0.028 13.6 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Pox_A32 PF04665.12 CBY24032.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 CBY24032.1 - 0.056 12.7 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CBY24032.1 - 0.071 13.5 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CBY24032.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBY24032.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CBY24032.1 - 0.18 11.0 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Inhibitor_I29 PF08246.12 CBY24033.1 - 0.072 13.5 0.2 0.18 12.3 0.2 1.7 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) POTRA_3 PF17287.2 CBY24033.1 - 0.089 12.3 0.2 14 5.3 0.2 2.8 2 0 0 2 2 2 0 POTRA domain POX PF07526.11 CBY24034.1 - 0.063 13.9 0.0 0.12 12.9 0.0 1.5 2 0 0 2 2 2 0 Associated with HOX MLANA PF14991.6 CBY24034.1 - 1.9 8.8 7.0 2.9 8.2 0.0 2.8 2 1 1 3 3 3 0 Protein melan-A Cullin PF00888.22 CBY24035.1 - 5.8e-136 454.6 10.0 8.9e-135 450.7 10.0 2.1 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBY24035.1 - 2.6e-26 91.4 2.1 2.6e-26 91.4 2.1 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain MarR_2 PF12802.7 CBY24035.1 - 0.0022 17.8 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 2 MarR family TrmB PF01978.19 CBY24035.1 - 0.067 13.1 0.6 3.9 7.4 0.1 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 CBY24035.1 - 1.2 9.6 3.5 15 6.1 0.4 3.3 2 1 1 3 3 3 0 Transcriptional regulator SpoIIE PF07228.12 CBY24036.1 - 2.8e-12 47.0 0.0 3.9e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CBY24036.1 - 4.3e-07 29.8 0.0 2.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY24036.1 - 0.00038 20.2 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C zf-C3HC PF07967.13 CBY24036.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 C3HC zinc finger-like DUF1043 PF06295.12 CBY24037.1 - 0.79 9.7 0.0 0.79 9.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4407 PF14362.6 CBY24037.1 - 2.2 7.6 13.9 1 8.7 9.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ALS2CR8 PF15299.6 CBY24039.1 - 0.21 11.5 0.6 0.44 10.4 0.2 1.8 2 0 0 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Kelch_4 PF13418.6 CBY24040.1 - 0.0074 16.3 4.7 0.68 10.0 0.1 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY24040.1 - 0.014 15.4 0.6 0.78 9.8 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 CBY24040.1 - 0.04 14.2 1.1 1.7 9.0 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Peptidase_C14 PF00656.22 CBY24042.1 - 2.5e-11 44.0 0.0 3.2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Virulence_RhuM PF13310.6 CBY24042.1 - 0.0075 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Virulence protein RhuM family adh_short PF00106.25 CBY24043.1 - 1.9e-22 79.7 0.1 1.2e-18 67.3 0.1 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY24043.1 - 2.5e-11 43.6 0.0 2.4e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY24043.1 - 5.4e-08 32.9 0.0 8.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 CBY24043.1 - 0.058 13.2 0.1 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CRR7 PF12095.8 CBY24043.1 - 0.071 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF2407_C PF13373.6 CBY24044.1 - 2 8.6 7.7 2.9 8.1 1.2 4.1 3 0 0 3 3 3 0 DUF2407 C-terminal domain 7tm_1 PF00001.21 CBY24045.1 - 6.7e-34 117.4 8.0 3.7e-20 72.4 0.4 2.4 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CBY24045.1 - 0.0016 17.8 3.9 0.0016 17.8 3.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DcuC PF03606.15 CBY24045.1 - 0.051 12.0 0.1 0.051 12.0 0.1 1.5 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier DUF4519 PF15012.6 CBY24045.1 - 0.31 11.2 3.0 4.2 7.6 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Trypsin PF00089.26 CBY24046.1 - 9e-51 172.8 0.6 9e-51 172.8 0.6 2.4 3 0 0 3 3 3 1 Trypsin TSP_1 PF00090.19 CBY24046.1 - 1.9e-11 44.0 46.6 1.5e-07 31.5 8.6 5.0 5 1 0 5 5 5 3 Thrombospondin type 1 domain Trypsin_2 PF13365.6 CBY24046.1 - 7.3e-06 26.9 0.0 1.7e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY24046.1 - 0.085 13.2 0.1 7.5 7.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 CBY24047.1 - 2.2e-18 66.9 0.1 3.4e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Trypsin MIF4G PF02854.19 CBY24048.1 - 1.6e-10 41.0 0.3 8.9e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 MIF4G domain Ank_2 PF12796.7 CBY24049.1 - 7.7e-13 48.8 0.4 2.1e-06 28.2 0.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY24049.1 - 1.9e-05 24.9 0.4 1.3 9.6 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 CBY24049.1 - 6.4e-05 23.4 0.1 0.0012 19.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24049.1 - 0.00082 19.6 0.3 0.022 15.3 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CBY24049.1 - 0.0093 16.3 0.0 0.035 14.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF326 PF03860.16 CBY24049.1 - 9.7 6.3 7.5 2.9 8.0 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF326) Fijivirus_P9-2 PF06837.11 CBY24050.1 - 0.011 15.2 1.1 0.45 9.9 0.6 2.4 1 1 0 2 2 2 0 Fijivirus P9-2 protein DUF3365 PF11845.8 CBY24050.1 - 0.023 15.0 1.6 0.047 14.0 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) Phenol_MetA_deg PF13557.6 CBY24050.1 - 0.078 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation bZIP_1 PF00170.21 CBY24050.1 - 2.2 8.4 5.7 0.52 10.4 0.7 2.3 2 0 0 2 2 2 0 bZIP transcription factor WBP-1 PF11669.8 CBY24051.1 - 0.00042 20.9 0.7 0.0011 19.6 0.7 1.7 1 1 0 1 1 1 1 WW domain-binding protein 1 TMIE PF16038.5 CBY24051.1 - 0.00075 19.3 3.6 0.0013 18.6 3.6 1.3 1 0 0 1 1 1 1 TMIE protein Shisa PF13908.6 CBY24051.1 - 0.0027 18.0 0.3 0.0072 16.6 0.0 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator MLANA PF14991.6 CBY24051.1 - 0.0033 17.7 0.1 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 Protein melan-A Comm PF15957.5 CBY24051.1 - 0.0059 16.9 0.0 0.0096 16.3 0.0 1.3 1 0 0 1 1 1 1 Commissureless GAPT PF11770.8 CBY24051.1 - 0.008 16.1 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) HemY_N PF07219.13 CBY24051.1 - 0.019 15.2 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Sarcoglycan_2 PF05510.13 CBY24051.1 - 0.056 12.2 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon EphA2_TM PF14575.6 CBY24051.1 - 0.068 14.0 0.0 0.18 12.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.11 CBY24051.1 - 0.13 12.3 0.7 13 5.8 0.4 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein TRP PF06011.12 CBY24051.1 - 0.17 10.6 0.1 0.24 10.1 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel SIT PF15330.6 CBY24051.1 - 0.18 12.3 0.9 0.29 11.6 0.1 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Baculo_11_kDa PF06143.11 CBY24051.1 - 3.6 7.2 9.4 6 6.5 8.6 1.8 1 1 0 1 1 1 0 Baculovirus 11 kDa family PMSR PF01625.21 CBY24052.1 - 0.11 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase Erf4 PF10256.9 CBY24054.1 - 0.093 12.8 0.0 0.11 12.6 0.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family TAFII28 PF04719.14 CBY24055.1 - 3.6e-32 110.3 0.2 7.6e-32 109.3 0.2 1.6 1 0 0 1 1 1 1 hTAFII28-like protein conserved region RasGAP_C PF03836.15 CBY24055.1 - 0.0045 17.1 0.3 0.0045 17.1 0.3 1.7 2 0 0 2 2 2 1 RasGAP C-terminus Glypican PF01153.19 CBY24055.1 - 0.041 12.7 4.0 0.057 12.3 4.0 1.1 1 0 0 1 1 1 0 Glypican RRM_1 PF00076.22 CBY24056.1 - 6.4e-25 86.8 1.5 2.9e-12 46.2 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY24056.1 - 1.4e-09 37.6 0.1 0.0012 18.4 0.5 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY24056.1 - 1.6e-07 31.1 0.2 0.0026 17.6 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CBY24056.1 - 0.031 14.4 0.0 5.8 7.1 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CBY24056.1 - 0.19 11.8 0.2 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF2605 PF10792.9 CBY24056.1 - 0.39 10.7 6.3 7.8 6.5 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2605) GET2 PF08690.10 CBY24056.1 - 0.5 10.0 13.6 0.76 9.4 13.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Rrn6 PF10214.9 CBY24056.1 - 9.2 4.6 7.3 12 4.2 7.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AAA PF00004.29 CBY24057.1 - 7.6e-35 120.2 0.0 2e-34 118.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY24057.1 - 2.6e-07 31.2 0.0 0.00029 21.3 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CBY24057.1 - 1.9e-06 28.0 0.0 4.7e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBY24057.1 - 5.7e-06 26.6 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CBY24057.1 - 5.8e-05 22.4 0.0 0.0002 20.6 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CBY24057.1 - 0.00026 21.3 0.6 0.0097 16.2 0.6 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBY24057.1 - 0.00075 19.3 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 CBY24057.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 CBY24057.1 - 0.0021 17.3 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain MCM PF00493.23 CBY24057.1 - 0.0027 16.8 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain AAA_24 PF13479.6 CBY24057.1 - 0.0037 17.0 0.1 0.011 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBY24057.1 - 0.0059 16.6 0.0 0.036 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CBY24057.1 - 0.017 15.1 1.7 2.5 8.0 0.0 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CBY24057.1 - 0.021 15.2 0.5 0.11 12.8 0.1 2.1 2 1 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 CBY24057.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CBY24057.1 - 0.03 14.1 4.0 0.15 11.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBY24057.1 - 0.031 13.8 0.0 0.091 12.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 CBY24057.1 - 0.047 13.3 0.2 0.17 11.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY24057.1 - 0.052 14.1 0.1 0.48 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CBY24057.1 - 0.058 13.6 0.0 0.46 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CBY24057.1 - 0.075 12.4 0.0 0.24 10.7 0.0 1.9 1 1 0 1 1 1 0 KaiC TsaE PF02367.17 CBY24057.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CBY24057.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 CBY24057.1 - 0.094 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 CBY24057.1 - 0.097 12.0 0.1 0.32 10.4 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pkinase PF00069.25 CBY24058.1 - 7e-72 241.9 0.0 7.9e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24058.1 - 1.1e-36 126.5 0.1 3.8e-36 124.7 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY24058.1 - 0.015 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like STAR_dimer PF16544.5 CBY24061.1 - 5.7e-35 118.7 4.7 1.4e-21 75.8 0.4 2.7 2 1 0 2 2 2 2 Homodimerisation region of STAR domain protein KH_1 PF00013.29 CBY24061.1 - 6.5e-07 29.1 0.1 1.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 KH domain Qua1 PF16274.5 CBY24061.1 - 0.56 10.1 5.1 2.7 7.9 0.1 3.4 3 1 0 3 3 3 0 Qua1 domain Kinesin PF00225.23 CBY24063.1 - 4.4e-112 374.3 0.5 4.4e-112 374.3 0.5 3.2 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY24063.1 - 8.8e-27 93.9 0.0 8.8e-27 93.9 0.0 3.1 4 0 0 4 4 4 1 Microtubule binding ApoLp-III PF07464.11 CBY24063.1 - 0.00023 21.3 5.6 0.00023 21.3 5.6 5.4 1 1 4 5 5 5 3 Apolipophorin-III precursor (apoLp-III) Filament PF00038.21 CBY24063.1 - 1 8.9 58.7 0.39 10.3 27.7 3.3 1 1 2 3 3 3 0 Intermediate filament protein CK2S PF15011.6 CBY24063.1 - 9 6.2 29.7 1 9.2 1.6 5.4 1 1 4 5 5 5 0 Casein Kinase 2 substrate Kinesin PF00225.23 CBY24065.1 - 2.5e-61 207.4 0.4 2.5e-61 207.4 0.4 2.4 2 1 0 2 2 2 1 Kinesin motor domain Prominin PF05478.11 CBY24065.1 - 3.1 5.6 24.0 3.2 5.6 12.6 2.2 1 1 1 2 2 2 0 Prominin T2SSF PF00482.23 CBY24065.1 - 5.6 6.9 5.7 2.6 8.0 2.9 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF883 PF05957.13 CBY24065.1 - 6.2 7.5 22.6 9.6 6.9 0.8 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Transglut_N PF00868.20 CBY24066.1 - 0.0039 17.5 0.1 0.22 11.9 0.0 3.0 2 1 1 3 3 3 1 Transglutaminase family PLAT PF01477.23 CBY24066.1 - 0.021 15.4 0.1 0.09 13.3 0.0 2.0 2 0 0 2 2 2 0 PLAT/LH2 domain Collagen PF01391.18 CBY24067.1 - 7.7e-68 224.1 283.1 6.3e-10 38.7 27.8 9.8 2 2 6 8 8 8 7 Collagen triple helix repeat (20 copies) TT_ORF2 PF02957.15 CBY24067.1 - 0.19 12.6 0.6 1.1 10.2 0.6 2.4 1 0 0 1 1 1 0 TT viral ORF2 PBD PF00786.28 CBY24068.1 - 0.012 16.0 0.1 0.041 14.2 0.1 2.0 1 0 0 1 1 1 0 P21-Rho-binding domain ELFV_dehydrog PF00208.21 CBY24069.1 - 3.9e-84 282.2 1.1 5.1e-84 281.8 1.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CBY24069.1 - 1.4e-53 180.2 0.0 3.6e-53 178.9 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 CBY24069.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CBY24069.1 - 0.0019 18.6 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ArgJ PF01960.18 CBY24070.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 ArgJ family Toxin_2 PF00451.19 CBY24070.1 - 2.4 8.5 9.6 1.1 9.7 1.2 3.4 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 VDE PF07137.11 CBY24070.1 - 4.6 6.7 12.9 0.27 10.7 7.9 1.5 2 0 0 2 2 2 0 VDE lipocalin domain zf-C2H2 PF00096.26 CBY24071.1 - 3.5e-08 33.5 6.1 9.6e-05 22.6 1.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY24071.1 - 4.1e-06 27.2 6.2 0.00038 21.0 1.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBY24071.1 - 5.1e-05 23.5 0.2 0.035 14.4 0.0 2.1 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY24071.1 - 0.00018 21.7 1.6 0.0034 17.7 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY24071.1 - 0.00042 20.2 3.1 0.0047 16.9 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY24071.1 - 0.0035 17.6 0.1 0.0035 17.6 0.1 1.7 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY24071.1 - 0.0074 16.7 9.2 0.095 13.2 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain CpXC PF14353.6 CBY24071.1 - 0.011 15.8 0.1 1.1 9.4 0.0 2.1 1 1 2 3 3 3 0 CpXC protein zf-nanos PF05741.13 CBY24071.1 - 0.014 15.6 1.3 0.85 9.9 0.5 2.5 2 1 0 2 2 2 0 Nanos RNA binding domain zf-C2H2_8 PF15909.5 CBY24071.1 - 0.021 15.1 0.2 0.025 14.9 0.2 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon DUF2225 PF09986.9 CBY24071.1 - 0.11 12.2 0.4 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_2 PF12756.7 CBY24071.1 - 0.13 12.6 0.2 4.2 7.7 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 CBY24071.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain FdhE PF04216.12 CBY24071.1 - 0.24 11.3 0.4 0.29 11.0 0.4 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Rubredoxin PF00301.20 CBY24071.1 - 0.39 10.8 2.4 18 5.5 0.5 2.4 2 0 0 2 2 2 0 Rubredoxin zf-BED PF02892.15 CBY24071.1 - 7.9 6.6 7.7 3.8 7.6 3.0 2.3 1 1 1 2 2 2 0 BED zinc finger Glyco_hydro_20 PF00728.22 CBY24072.1 - 1.2e-54 186.1 0.5 7.1e-34 117.7 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain zf-C2H2 PF00096.26 CBY24073.1 - 6.5e-07 29.5 6.1 0.0005 20.4 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY24073.1 - 8.8e-05 23.0 6.2 0.002 18.8 1.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 CBY24073.1 - 0.00082 19.6 0.2 60 4.0 0.1 2.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CBY24073.1 - 0.0067 16.4 3.1 0.025 14.6 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY24073.1 - 0.013 15.8 1.5 0.018 15.3 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY24073.1 - 0.014 15.8 4.3 0.017 15.5 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CBY24073.1 - 0.026 14.8 0.7 0.058 13.7 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-nanos PF05741.13 CBY24073.1 - 0.1 12.8 0.2 3.3 8.0 0.0 2.6 2 0 0 2 2 2 0 Nanos RNA binding domain CpXC PF14353.6 CBY24073.1 - 0.11 12.6 0.9 6.6 6.8 0.0 2.8 2 1 1 3 3 3 0 CpXC protein Zn-C2H2_12 PF18112.1 CBY24073.1 - 0.12 12.9 0.0 1.7 9.2 0.0 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 CBY24073.1 - 0.26 11.8 9.3 0.57 10.7 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Asp-B-Hydro_N PF05279.11 CBY24073.1 - 2.1 8.4 10.7 3 7.8 10.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Kinesin PF00225.23 CBY24074.1 - 2.1e-103 345.8 3.9 4.5e-103 344.7 3.9 1.6 1 0 0 1 1 1 1 Kinesin motor domain MyTH4 PF00784.17 CBY24074.1 - 1.3e-77 257.2 13.5 6.2e-30 103.9 0.0 4.8 4 0 0 4 4 4 3 MyTH4 domain Microtub_bd PF16796.5 CBY24074.1 - 3.1e-45 153.8 0.1 3.1e-45 153.8 0.1 3.3 3 0 0 3 3 3 1 Microtubule binding FERM_M PF00373.18 CBY24074.1 - 4.5e-18 65.8 3.5 3e-09 37.3 0.0 5.1 4 0 0 4 4 4 3 FERM central domain FERM_N PF09379.10 CBY24074.1 - 5.6e-12 45.4 0.2 0.042 13.8 0.0 4.1 3 0 0 3 3 3 3 FERM N-terminal domain PAZ PF02170.22 CBY24074.1 - 8.2e-11 41.9 0.1 1.1e-09 38.2 0.0 2.6 2 0 0 2 2 2 1 PAZ domain ArgoL1 PF08699.10 CBY24074.1 - 8.8e-07 28.5 0.0 2.6e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 CBY24074.1 - 4.1e-05 24.2 1.0 0.0002 22.0 1.0 2.4 1 0 0 1 1 1 1 N-terminal domain of argonaute KASH_CCD PF14662.6 CBY24074.1 - 0.0096 15.8 31.8 0.21 11.4 24.8 2.8 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH AAA_22 PF13401.6 CBY24074.1 - 0.059 13.7 0.0 27 5.0 0.0 3.6 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 CBY24074.1 - 0.08 12.5 12.6 0.48 9.9 12.6 2.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec34 PF04136.15 CBY24074.1 - 0.62 9.9 20.4 0.38 10.6 3.5 3.2 2 1 1 3 3 2 0 Sec34-like family MetOD2 PF18548.1 CBY24074.1 - 1.3 9.2 10.0 4.2 7.5 2.5 3.5 2 0 0 2 2 2 0 Metanogen output domain 2 DUF3450 PF11932.8 CBY24074.1 - 2.5 7.3 23.2 7.6 5.8 11.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 CBY24074.1 - 3.6 7.6 27.4 6.2 6.9 6.2 5.6 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 CBY24074.1 - 3.8 7.5 15.3 2.7 8.0 8.9 3.2 1 1 1 2 2 2 0 Laminin Domain II TolA_bind_tri PF16331.5 CBY24074.1 - 5.1 7.2 20.3 2.2 8.4 7.2 3.6 2 1 0 2 2 2 0 TolA binding protein trimerisation FapA PF03961.13 CBY24074.1 - 7.6 5.0 29.2 10 4.6 11.3 2.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A ATG16 PF08614.11 CBY24074.1 - 10 6.3 27.5 93 3.2 6.0 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Glyco_hydro_20 PF00728.22 CBY24075.1 - 6.9e-19 68.4 0.0 1.2e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Kinesin PF00225.23 CBY24076.1 - 5.8e-104 347.6 3.8 5.8e-104 347.6 3.8 2.1 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CBY24076.1 - 8.4e-46 155.6 0.1 2.1e-45 154.3 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding MAD PF05557.13 CBY24076.1 - 0.00028 19.4 24.9 0.00057 18.4 24.9 1.4 1 0 0 1 1 1 1 Mitotic checkpoint protein Sec34 PF04136.15 CBY24076.1 - 0.053 13.4 19.1 0.063 13.2 2.6 3.2 1 1 2 3 3 3 0 Sec34-like family GAS PF13851.6 CBY24076.1 - 0.097 12.0 34.9 0.041 13.2 19.6 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 CBY24076.1 - 0.1 11.9 25.2 0.54 9.5 11.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 CBY24076.1 - 0.26 11.8 37.2 0.2 12.2 17.2 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 CBY24076.1 - 0.41 10.7 24.0 1.2 9.2 5.8 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBY24076.1 - 0.43 9.4 34.4 0.45 9.3 18.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.12 CBY24076.1 - 0.48 10.4 15.8 0.45 10.5 9.1 3.0 2 0 0 2 2 2 0 Laminin Domain II HIP1_clath_bdg PF16515.5 CBY24076.1 - 0.63 10.7 30.2 0.44 11.2 13.3 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF16 PF01519.16 CBY24076.1 - 0.76 10.3 22.9 4.6 7.8 15.8 3.4 2 1 1 3 3 2 0 Protein of unknown function DUF16 TPR_MLP1_2 PF07926.12 CBY24076.1 - 0.83 9.7 34.5 0.051 13.6 27.8 2.6 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein XhlA PF10779.9 CBY24076.1 - 1.9 8.8 26.5 2 8.7 2.6 4.6 2 1 1 3 3 3 0 Haemolysin XhlA DUF2968 PF11180.8 CBY24076.1 - 3 7.4 22.5 3.7 7.1 7.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Prominin PF05478.11 CBY24076.1 - 3.2 5.6 12.9 5.8 4.7 12.9 1.4 1 0 0 1 1 1 0 Prominin TolA_bind_tri PF16331.5 CBY24076.1 - 3.8 7.7 23.8 0.092 12.8 3.8 3.4 2 1 1 3 3 3 0 TolA binding protein trimerisation UPF0449 PF15136.6 CBY24076.1 - 5.1 7.6 22.7 1.2 9.6 7.8 2.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF812 PF05667.11 CBY24076.1 - 5.2 5.8 38.0 22 3.8 33.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 CBY24076.1 - 5.3 7.1 41.9 0.2 11.7 17.2 3.0 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERK-JNK_inhib PF15002.6 CBY24077.1 - 5.5e-58 195.9 10.0 6.3e-58 195.7 10.0 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor HMG_box_5 PF14887.6 CBY24077.1 - 0.034 14.1 0.3 0.034 14.1 0.3 2.1 3 0 0 3 3 3 0 HMG (high mobility group) box 5 DUF3527 PF12043.8 CBY24077.1 - 0.089 12.3 0.2 0.089 12.3 0.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3527) TrwC PF08751.11 CBY24077.1 - 0.78 9.2 4.6 0.73 9.3 1.5 1.9 1 1 1 2 2 2 0 TrwC relaxase NERD PF08378.11 CBY24078.1 - 0.00016 22.1 0.0 0.0003 21.2 0.0 1.4 1 0 0 1 1 1 1 Nuclease-related domain EF-hand_1 PF00036.32 CBY24079.1 - 2.5e-15 54.8 0.5 1.6e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY24079.1 - 1.8e-12 46.1 0.5 8.8e-05 22.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBY24079.1 - 2.9e-12 46.9 0.4 8.1e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY24079.1 - 7.1e-12 44.3 0.8 0.00013 21.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY24079.1 - 1.5e-07 31.2 0.7 0.0057 16.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 CBY24079.1 - 0.00012 21.9 1.1 0.0099 15.8 0.0 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY24079.1 - 0.0012 19.2 0.1 0.0022 18.3 0.1 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Glyco_transf_90 PF05686.12 CBY24081.1 - 2.7e-72 243.9 6.0 3.6e-72 243.4 6.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 CBY24081.1 - 0.0089 16.4 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Phospholip_A2_1 PF00068.19 CBY24083.1 - 4.1e-11 43.3 10.6 4.1e-11 43.3 10.6 2.2 2 0 0 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.12 CBY24083.1 - 0.28 11.8 5.2 0.57 10.8 4.2 1.9 2 0 0 2 2 2 0 Poxvirus A21 Protein P5CR_dimer PF14748.6 CBY24084.1 - 2.3e-39 133.8 1.1 5.1e-39 132.7 1.1 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CBY24084.1 - 2.5e-14 53.6 0.1 5.7e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CBY24084.1 - 0.00035 20.8 0.3 0.00062 20.0 0.3 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RcsD_ABL PF16359.5 CBY24084.1 - 0.041 14.0 0.0 3.6 7.8 0.0 2.2 2 0 0 2 2 2 0 RcsD-ABL domain Ribosomal_S11 PF00411.19 CBY24084.1 - 0.053 13.9 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S11 C6_DPF PF10170.9 CBY24084.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 1 1 0 1 1 1 0 Cysteine-rich domain zf-3CxxC_2 PF17180.4 CBY24085.1 - 3.1e-23 82.3 21.9 8.7e-22 77.6 8.4 3.0 3 0 0 3 3 3 2 Zinc-binding domain UPF0515 PF15135.6 CBY24085.1 - 0.00046 19.6 10.3 0.0009 18.7 10.3 1.4 1 1 0 1 1 1 1 Uncharacterised protein UPF0515 Zn-ribbon_8 PF09723.10 CBY24085.1 - 0.0086 16.2 2.8 0.0086 16.2 2.8 3.8 4 1 0 4 4 4 2 Zinc ribbon domain zf_UBZ PF18439.1 CBY24085.1 - 0.023 14.3 0.4 0.023 14.3 0.4 5.4 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 CBY24085.1 - 0.094 12.8 0.2 0.094 12.8 0.2 5.0 5 1 0 5 5 5 0 C2H2-type zinc finger DZR PF12773.7 CBY24085.1 - 0.47 10.5 20.6 3.7 7.7 7.5 3.4 1 1 1 2 2 2 0 Double zinc ribbon zf-3CxxC PF13695.6 CBY24085.1 - 0.78 10.3 28.8 5.2 7.6 12.5 4.7 2 2 0 2 2 2 0 Zinc-binding domain HypA PF01155.19 CBY24085.1 - 3.3 7.8 24.8 0.14 12.1 1.8 3.5 2 2 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_2 PF13465.6 CBY24085.1 - 4.2 8.0 27.0 6 7.5 0.2 6.0 6 0 0 6 6 6 0 Zinc-finger double domain zf-ACC PF17848.1 CBY24085.1 - 4.5 7.4 11.8 1.4 9.1 0.1 4.0 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf-DBF PF07535.12 CBY24086.1 - 0.0013 18.8 0.9 0.0013 18.8 0.9 2.1 2 0 0 2 2 2 1 DBF zinc finger TetR_C_2 PF08361.11 CBY24086.1 - 0.024 14.7 0.1 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region CYLD_phos_site PF16607.5 CBY24087.1 - 0.32 10.8 8.0 0.059 13.2 3.8 1.9 2 0 0 2 2 2 0 Phosphorylation region of CYLD, unstructured PLAC8 PF04749.17 CBY24089.1 - 8e-14 52.4 10.9 9.6e-14 52.2 10.9 1.1 1 0 0 1 1 1 1 PLAC8 family C6_DPF PF10170.9 CBY24089.1 - 0.66 10.4 9.2 2.5 8.5 0.4 2.1 1 1 1 2 2 2 0 Cysteine-rich domain KCNQC3-Ank-G_bd PF11956.8 CBY24090.1 - 0.078 13.3 0.5 0.19 12.0 0.5 1.9 1 1 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 EGF_CA PF07645.15 CBY24092.1 - 0 1850.0 1583.6 2.6e-11 43.5 11.1 91.4 84 9 6 91 91 91 81 Calcium-binding EGF domain EGF_3 PF12947.7 CBY24092.1 - 0 1398.1 1455.3 9.1e-10 38.6 12.2 90.3 83 8 7 91 91 91 84 EGF domain cEGF PF12662.7 CBY24092.1 - 0 1026.5 989.3 1.1e-08 34.8 3.4 91.7 88 5 1 89 89 89 80 Complement Clr-like EGF-like EGF PF00008.27 CBY24092.1 - 2.7e-180 583.9 1195.3 4e-06 27.0 6.9 89.3 82 6 5 87 87 87 74 EGF-like domain EGF_MSP1_1 PF12946.7 CBY24092.1 - 4.5e-110 359.4 1194.4 4.3e-05 23.5 6.8 86.2 82 6 6 88 88 88 62 MSP1 EGF domain 1 hEGF PF12661.7 CBY24092.1 - 2.2e-102 332.6 993.5 0.00055 20.5 3.1 92.0 89 0 0 89 89 89 69 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY24092.1 - 2.5e-23 82.0 1233.9 0.012 15.9 2.5 86.2 53 22 31 84 84 84 51 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY24092.1 - 7.8e-12 45.3 1198.8 0.0034 17.7 5.1 85.4 80 9 6 86 86 86 50 Pvs28 EGF domain EF-hand_1 PF00036.32 CBY24095.1 - 3.1e-24 82.7 2.3 2.9e-07 29.5 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CBY24095.1 - 6.6e-22 77.7 0.2 5.6e-14 52.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY24095.1 - 5e-21 72.8 0.3 8e-06 25.4 0.1 4.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 CBY24095.1 - 6e-18 63.5 2.6 1.6e-06 27.3 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CBY24095.1 - 8.1e-14 51.2 6.3 0.00048 19.9 0.3 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CBY24095.1 - 4.5e-06 26.6 0.0 0.013 15.5 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY24095.1 - 0.0059 16.9 0.1 0.46 10.8 0.0 2.9 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CBY24095.1 - 0.011 15.6 0.8 3.2 7.6 0.0 3.3 2 1 2 4 4 4 0 Caleosin related protein EF-hand_9 PF14658.6 CBY24095.1 - 0.012 15.9 0.0 0.067 13.5 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 CBY24095.1 - 0.036 14.3 0.1 7.5 6.8 0.0 2.6 2 1 1 3 3 3 0 Dockerin type I domain Homez PF11569.8 CBY24095.1 - 0.085 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez TcdB_toxin_midN PF12256.8 CBY24095.1 - 0.095 12.1 0.0 8.8 5.7 0.0 2.2 1 1 1 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region VESA1_N PF12785.7 CBY24096.1 - 0.13 11.2 4.4 0.15 11.0 4.4 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 EGF PF00008.27 CBY24097.1 - 2.1e-10 40.7 19.7 2.1e-06 27.9 4.8 4.0 4 0 0 4 4 4 2 EGF-like domain EGF_2 PF07974.13 CBY24097.1 - 0.023 15.1 4.1 0.023 15.1 4.1 3.6 3 1 0 3 3 3 0 EGF-like domain Phospholip_A2_1 PF00068.19 CBY24098.1 - 1.6e-07 31.8 5.1 1.9e-07 31.5 5.1 1.1 1 0 0 1 1 1 1 Phospholipase A2 TPR_21 PF09976.9 CBY24099.1 - 0.0034 17.1 0.3 0.0047 16.7 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain BatD PF13584.6 CBY24099.1 - 0.02 13.7 0.9 0.024 13.5 0.9 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4366 PF14283.6 CBY24099.1 - 0.049 13.7 4.0 0.059 13.4 0.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4366) SWIRM-assoc_2 PF16496.5 CBY24099.1 - 0.067 12.1 4.8 0.08 11.8 4.8 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal TMEM208_SND2 PF05620.11 CBY24099.1 - 0.64 9.8 6.2 0.26 11.1 0.3 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Homeodomain PF00046.29 CBY24100.1 - 2.5e-20 72.0 10.2 7.1e-20 70.6 10.2 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY24100.1 - 0.032 14.1 1.6 0.032 14.1 1.6 2.7 2 1 1 3 3 3 0 Homeobox KN domain Homez PF11569.8 CBY24100.1 - 0.15 11.5 0.2 0.37 10.3 0.2 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF536 PF04394.14 CBY24100.1 - 0.53 10.2 3.1 2.8 7.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF536 zf-C2H2 PF00096.26 CBY24101.1 - 3e-16 58.9 21.3 2.9e-06 27.4 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY24101.1 - 1.3e-11 44.3 9.6 1.4e-07 31.6 2.7 4.5 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY24101.1 - 6.1e-10 39.1 18.6 0.0016 19.1 2.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY24101.1 - 0.0017 18.6 3.0 0.73 10.2 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CBY24101.1 - 0.0022 18.6 6.5 0.3 11.8 0.1 3.0 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CBY24101.1 - 0.035 14.1 1.4 0.035 14.1 1.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CBY24101.1 - 0.23 11.9 6.0 2.3 8.7 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CBY24101.1 - 0.3 11.2 2.8 7.2 6.7 0.7 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 CBY24101.1 - 0.51 10.1 18.9 0.054 13.3 2.8 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-TRAF PF02176.18 CBY24101.1 - 2.5 8.9 5.6 0.62 10.8 0.9 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 CBY24101.1 - 2.9 7.7 9.8 7.2 6.5 0.0 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CBY24101.1 - 6.3 7.2 7.6 1.6 9.1 1.5 2.5 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CBY24101.1 - 8.2 7.0 7.3 22 5.6 2.0 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RRM_1 PF00076.22 CBY24102.1 - 1.5e-09 37.5 1.7 2.2e-09 37.0 0.0 2.2 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY24102.1 - 0.033 14.3 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif CK_II_beta PF01214.18 CBY24103.1 - 2.1e-73 246.1 0.1 2.4e-73 245.8 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit AAA PF00004.29 CBY24104.1 - 2e-15 57.4 0.0 6.4e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY24104.1 - 4.6e-11 43.2 0.0 2.9e-10 40.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY24104.1 - 9.3e-10 39.1 0.0 4.5e-08 33.7 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.18 CBY24104.1 - 1.1e-09 38.1 1.3 3.2e-09 36.7 1.3 1.8 1 0 0 1 1 1 1 BAH domain Cdc6_C PF09079.11 CBY24104.1 - 8.6e-06 25.7 0.1 0.00089 19.2 0.0 3.3 3 0 0 3 3 3 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 CBY24104.1 - 1.7e-05 24.9 0.0 6.8e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 CBY24104.1 - 0.0038 17.6 0.4 0.015 15.6 0.4 2.0 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 CBY24104.1 - 0.009 15.2 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase NACHT PF05729.12 CBY24104.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 CBY24104.1 - 0.095 12.7 0.0 0.095 12.7 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CBY24104.1 - 0.15 12.5 0.2 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DALR_1 PF05746.15 CBY24105.1 - 2.8e-10 40.4 0.0 5.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Endonuclease_NS PF01223.23 CBY24106.1 - 1.1e-54 185.7 0.0 1.3e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease dsrm PF00035.26 CBY24107.1 - 1.4e-16 60.9 0.4 2.1e-07 31.5 0.0 3.9 2 1 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 CBY24107.1 - 0.099 12.9 0.2 4.6 7.6 0.0 2.9 3 1 0 3 3 3 0 double strand RNA binding domain from DEAD END PROTEIN 1 PHR PF08005.12 CBY24108.1 - 1.2e-48 165.6 1.1 1.2e-48 165.6 1.1 1.5 2 0 0 2 2 2 1 PHR domain BTB PF00651.31 CBY24108.1 - 2.7e-26 92.0 0.5 1.2e-24 86.7 0.0 2.7 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 CBY24108.1 - 1.4e-10 41.2 0.1 3e-09 36.9 0.0 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 CBY24108.1 - 0.094 12.8 1.5 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) RCR PF12273.8 CBY24109.1 - 0.025 15.2 0.2 0.04 14.6 0.2 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Trypsin PF00089.26 CBY24110.1 - 7.1e-15 55.4 1.3 1.6e-14 54.3 0.3 1.8 2 0 0 2 2 2 1 Trypsin Prefoldin_2 PF01920.20 CBY24112.1 - 3.3e-16 59.2 10.3 3.3e-16 59.2 10.3 1.8 1 1 1 2 2 2 1 Prefoldin subunit DUF948 PF06103.11 CBY24112.1 - 0.066 13.5 9.0 1.8 8.9 3.5 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 CBY24112.1 - 0.16 12.5 16.1 0.37 11.3 16.1 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4618 PF15397.6 CBY24112.1 - 0.25 10.7 15.7 0.25 10.7 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) IFT57 PF10498.9 CBY24112.1 - 0.25 10.2 15.0 1.4 7.8 7.3 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 COG2 PF06148.11 CBY24112.1 - 0.31 11.1 10.0 0.19 11.8 1.1 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BRE1 PF08647.11 CBY24112.1 - 0.5 10.5 18.8 0.24 11.5 2.6 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 CBY24112.1 - 0.61 10.2 14.9 0.75 9.9 14.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 CBY24112.1 - 0.88 9.6 13.0 3 7.9 1.4 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 CBY24112.1 - 0.95 9.5 13.3 1.9 8.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BST2 PF16716.5 CBY24112.1 - 1 10.0 16.3 0.8 10.3 2.1 2.2 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 LMBR1 PF04791.16 CBY24112.1 - 1.1 8.1 9.2 1.2 8.0 9.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein T3SSipB PF16535.5 CBY24112.1 - 1.4 9.4 15.0 6.7 7.2 0.7 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF4200 PF13863.6 CBY24112.1 - 1.5 9.3 18.3 0.48 10.8 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-H PF05837.12 CBY24112.1 - 1.6 9.2 12.8 7.3 7.0 11.7 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Nucleoporin_FG2 PF15967.5 CBY24112.1 - 1.9 6.9 5.4 2.1 6.8 5.4 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Sec2p PF06428.11 CBY24112.1 - 2 8.4 16.7 0.078 13.0 2.4 2.5 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Prefoldin PF02996.17 CBY24112.1 - 2 8.3 19.0 0.92 9.4 1.8 3.0 2 1 1 3 3 3 0 Prefoldin subunit Synaptobrevin PF00957.21 CBY24112.1 - 2.5 8.0 10.3 7.3 6.5 3.7 2.6 3 0 0 3 3 3 0 Synaptobrevin OmpH PF03938.14 CBY24112.1 - 2.6 8.4 22.3 1.2 9.4 4.0 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 CBY24112.1 - 3.4 7.4 16.5 6.7 6.5 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 CBY24112.1 - 3.7 7.9 15.2 1.5 9.2 1.8 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CBY24112.1 - 3.8 6.3 19.1 34 3.2 19.2 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2408 PF10303.9 CBY24112.1 - 5.6 7.5 12.3 2.3e+02 2.3 12.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Seryl_tRNA_N PF02403.22 CBY24112.1 - 7.4 6.9 17.2 0.8 10.0 1.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CR6_interact PF10147.9 CBY24112.1 - 8.8 6.0 14.8 3.6 7.2 8.1 2.0 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Ribosomal_L16 PF00252.18 CBY24113.1 - 6.8e-06 26.1 0.0 8.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e GYD PF08734.11 CBY24113.1 - 0.097 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 GYD domain GCP_N_terminal PF17681.1 CBY24114.1 - 2.1e-15 57.2 0.0 3.2e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CBY24114.1 - 8.7e-09 35.3 2.9 0.0012 18.4 0.3 3.1 3 0 0 3 3 3 2 Gamma tubulin complex component C-terminal PAP_assoc PF03828.19 CBY24115.1 - 7.8e-14 51.6 0.0 1.8e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY24115.1 - 1.7e-11 44.3 0.0 3.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBY24115.1 - 0.0032 17.5 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Apocytochr_F_N PF16639.5 CBY24115.1 - 0.087 13.1 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Apocytochrome F, N-terminal WD40 PF00400.32 CBY24116.1 - 8.2e-13 48.6 11.5 0.0063 17.3 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY24116.1 - 0.028 13.4 0.7 3.7 6.4 0.4 3.4 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein YqgF PF14639.6 CBY24116.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 STATa_Ig PF18214.1 CBY24116.1 - 0.12 12.4 1.1 0.21 11.6 1.1 1.4 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain zf-C3H1 PF10650.9 CBY24117.1 - 0.022 14.5 0.6 0.058 13.1 0.6 1.8 1 0 0 1 1 1 0 Putative zinc-finger domain Ras PF00071.22 CBY24118.1 - 4e-60 202.1 0.0 4.7e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY24118.1 - 1.7e-32 112.1 0.2 3.5e-32 111.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY24118.1 - 4.1e-15 55.7 0.0 5.7e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY24118.1 - 6.3e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY24118.1 - 0.00019 21.1 0.0 0.0041 16.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY24118.1 - 0.00032 20.1 0.0 0.00048 19.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBY24118.1 - 0.00047 20.1 0.0 1 9.2 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 CBY24118.1 - 0.041 14.2 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CBY24118.1 - 0.041 13.6 0.0 0.057 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain TetR_C_16 PF17920.1 CBY24118.1 - 0.047 13.9 0.0 0.089 13.0 0.0 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_22 PF13401.6 CBY24118.1 - 0.076 13.3 0.1 0.17 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 CBY24118.1 - 0.077 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin DAP3 PF10236.9 CBY24118.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.29 CBY24118.1 - 0.13 12.7 0.0 2.1 8.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Steroid_dh PF02544.16 CBY24119.1 - 4.7e-29 101.3 4.1 9.4e-29 100.3 4.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 CBY24119.1 - 6.9e-05 22.5 0.1 0.00012 21.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CBY24119.1 - 0.058 14.0 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PH PF00169.29 CBY24120.1 - 4.5e-06 27.1 0.1 1.1e-05 25.8 0.1 1.6 1 0 0 1 1 1 1 PH domain DUF5377 PF17347.2 CBY24120.1 - 0.097 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5377) zf-C3HC4_2 PF13923.6 CBY24121.1 - 2.4e-10 40.1 9.3 4.7e-10 39.1 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY24121.1 - 1.5e-06 28.1 7.8 1.5e-06 28.1 6.2 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY24121.1 - 2.2e-06 27.4 10.3 4.1e-06 26.6 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY24121.1 - 5.9e-06 26.5 8.6 1.2e-05 25.6 8.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY24121.1 - 2.4e-05 24.1 8.1 4.1e-05 23.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY24121.1 - 0.00058 19.8 12.1 0.0032 17.4 12.3 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBY24121.1 - 0.0012 18.9 8.6 0.0012 18.9 8.6 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBY24121.1 - 0.0061 16.4 11.6 0.78 9.6 12.3 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CBY24121.1 - 0.06 13.2 5.8 0.13 12.1 5.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 CBY24121.1 - 0.12 12.6 9.0 0.62 10.4 9.0 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CBY24121.1 - 0.21 11.8 5.6 0.39 10.9 5.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 CBY24121.1 - 0.24 11.3 3.5 0.44 10.4 3.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 CBY24121.1 - 0.49 10.3 8.4 1.5 8.8 8.4 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RabGAP-TBC PF00566.18 CBY24122.1 - 4.2e-53 180.2 0.1 4.2e-53 180.2 0.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AAA_18 PF13238.6 CBY24122.1 - 3 8.4 9.9 46 4.6 6.4 3.1 2 1 0 2 2 2 0 AAA domain DIRP PF06584.13 CBY24123.1 - 1.8e-37 127.7 0.2 4e-37 126.6 0.2 1.6 1 0 0 1 1 1 1 DIRP KxDL PF10241.9 CBY24123.1 - 0.0062 16.8 0.4 0.02 15.2 0.4 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF2524 PF10732.9 CBY24123.1 - 0.022 15.0 0.5 0.39 11.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) HNF-1_N PF04814.13 CBY24124.1 - 4.6 7.8 8.9 7.8 7.1 8.5 1.6 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus BIR PF00653.21 CBY24125.1 - 2.4e-31 108.2 3.0 3.9e-16 59.4 0.2 3.4 3 1 1 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 CBY24125.1 - 6.1e-09 35.6 14.0 6.1e-09 35.6 14.0 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY24125.1 - 0.7 9.8 15.3 0.7 9.8 13.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ribbon_3 PF13248.6 CBY24125.1 - 4.5 6.8 7.0 7.1 6.2 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain DUF5577 PF17740.1 CBY24126.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5577) EGF PF00008.27 CBY24127.1 - 7.2e-134 435.4 455.8 2.4e-07 30.9 9.6 29.3 29 0 0 29 29 29 22 EGF-like domain hEGF PF12661.7 CBY24127.1 - 2.8e-62 205.4 379.3 0.00015 22.3 4.7 29.6 30 0 0 30 30 30 23 Human growth factor-like EGF EGF_2 PF07974.13 CBY24127.1 - 1.5e-43 146.8 473.2 0.0079 16.5 10.3 28.9 27 1 1 28 28 28 22 EGF-like domain VWA_2 PF13519.6 CBY24127.1 - 3.5e-08 34.1 0.8 3.5e-08 34.1 0.8 2.8 2 1 0 2 2 2 1 von Willebrand factor type A domain cEGF PF12662.7 CBY24127.1 - 1.4e-06 28.1 317.5 0.008 16.1 3.1 25.9 27 0 0 27 27 27 19 Complement Clr-like EGF-like PIN PF01850.21 CBY24128.1 - 0.07 13.6 0.2 0.13 12.8 0.1 1.6 2 0 0 2 2 2 0 PIN domain Glyco_hydro_9 PF00759.19 CBY24130.1 - 7.4e-122 407.7 6.2 1e-121 407.2 6.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF3747 PF12565.8 CBY24130.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) DPBB_1 PF03330.18 CBY24130.1 - 0.098 12.9 2.4 0.15 12.3 0.2 2.5 3 0 0 3 3 3 0 Lytic transglycolase Aminotran_3 PF00202.21 CBY24131.1 - 3.5e-115 384.9 0.0 4.2e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Oscp1 PF10188.9 CBY24132.1 - 2.1e-48 164.7 4.0 3.6e-48 164.0 4.0 1.4 1 0 0 1 1 1 1 Organic solute transport protein 1 zf-ANAPC11 PF12861.7 CBY24132.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.22 CBY24134.1 - 9.9e-27 92.6 0.0 9.7e-16 57.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY24134.1 - 5.5e-05 23.2 0.8 0.18 12.0 0.1 3.3 3 1 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 CBY24134.1 - 0.015 14.9 0.0 0.9 9.1 0.0 2.7 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.6 CBY24134.1 - 0.031 14.1 0.0 6.2 6.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4651) RRM_3 PF08777.11 CBY24134.1 - 0.062 13.4 0.0 9.4 6.3 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif YpsA PF06908.11 CBY24135.1 - 0.044 13.8 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 YspA SLOG family Arf PF00025.21 CBY24136.1 - 3.2e-45 153.7 0.1 3.8e-45 153.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY24136.1 - 1.3e-15 57.7 0.1 1.8e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY24136.1 - 2.8e-12 46.6 0.1 3.4e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CBY24136.1 - 1.5e-11 44.0 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBY24136.1 - 7.4e-11 41.8 1.3 1.8e-06 27.4 0.6 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY24136.1 - 4.5e-09 36.0 0.0 5.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY24136.1 - 2e-07 31.1 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY24136.1 - 0.0041 17.4 0.1 0.2 12.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CBY24136.1 - 0.027 14.0 0.5 0.078 12.5 0.1 2.1 2 1 1 3 3 3 0 Ferrous iron transport protein B Ank_2 PF12796.7 CBY24138.1 - 2.1e-19 69.9 0.1 1e-10 42.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY24138.1 - 1.9e-15 57.0 0.2 4.2e-07 30.4 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SET PF00856.28 CBY24138.1 - 3e-14 53.8 5.0 4e-13 50.1 0.2 3.2 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 CBY24138.1 - 1.4e-12 48.3 4.6 1.4e-12 48.3 4.6 3.6 3 0 0 3 3 3 2 Pre-SET motif Ank_3 PF13606.6 CBY24138.1 - 4e-12 45.2 0.0 0.28 11.9 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CBY24138.1 - 8.6e-11 41.9 0.6 0.04 14.2 0.0 4.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY24138.1 - 7.2e-06 26.2 0.1 1.3 9.6 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Transglut_i_TM PF14400.6 CBY24138.1 - 0.0096 16.0 1.0 0.64 10.1 0.0 2.4 2 0 0 2 2 2 1 Inactive transglutaminase fused to 7 transmembrane helices zf-CCHC_3 PF13917.6 CBY24139.1 - 7.7e-07 29.0 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Rtf2 PF04641.12 CBY24139.1 - 0.0013 18.2 3.6 0.0013 18.2 3.6 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-CCHC PF00098.23 CBY24139.1 - 0.0015 18.5 4.0 0.0024 17.9 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Peptidase_S49_N PF08496.10 CBY24139.1 - 2.4 8.2 8.7 3.3 7.8 8.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1509 PF07420.11 CBY24139.1 - 3.1 6.7 8.9 3.7 6.4 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) An_peroxidase PF03098.15 CBY24140.1 - 4.8e-177 589.7 0.0 6.6e-177 589.3 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 CBY24140.1 - 1.9e-37 127.2 0.0 3.9e-13 49.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY24140.1 - 2.1e-28 98.7 0.5 1.3e-08 35.3 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CBY24140.1 - 1.5e-22 79.7 0.2 3.1e-07 30.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CBY24140.1 - 2.7e-22 78.7 0.3 5.5e-07 29.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain LRR_8 PF13855.6 CBY24140.1 - 3.6e-15 55.5 3.2 2.6e-13 49.5 1.9 2.5 2 0 0 2 2 2 1 Leucine rich repeat V-set PF07686.17 CBY24140.1 - 1.3e-07 31.7 1.6 0.6 10.3 0.0 5.0 4 2 0 4 4 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY24140.1 - 3.8e-06 26.4 0.0 2 8.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 CBY24140.1 - 9.3e-06 25.8 0.0 3.1 8.1 0.0 4.1 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain LRR_4 PF12799.7 CBY24140.1 - 0.00011 22.5 8.5 0.0015 18.9 0.3 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY24140.1 - 0.00026 21.0 0.3 0.00094 19.1 0.2 1.9 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Herpes_gE PF02480.16 CBY24140.1 - 0.00073 18.4 0.0 0.81 8.4 0.0 2.8 3 0 0 3 3 3 2 Alphaherpesvirus glycoprotein E C1-set PF07654.15 CBY24140.1 - 0.00078 19.8 0.1 0.21 12.0 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 CBY24140.1 - 0.0031 17.5 0.0 0.0095 16.0 0.0 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain LRR_1 PF00560.33 CBY24140.1 - 0.0038 17.6 0.7 2.5 9.0 0.0 4.5 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 CBY24140.1 - 0.015 14.8 0.2 0.031 13.8 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat MCM6_C PF18263.1 CBY24140.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain LRRNT PF01462.18 CBY24140.1 - 0.59 9.8 4.2 2 8.1 4.2 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain WD40 PF00400.32 CBY24141.1 - 1.1e-61 203.3 75.5 3.4e-05 24.5 0.0 26.8 28 0 0 28 28 28 12 WD domain, G-beta repeat HELP PF03451.14 CBY24141.1 - 8.4e-43 144.1 0.1 1.3e-15 57.0 0.0 3.4 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 CBY24141.1 - 5.2e-37 126.0 7.2 3.8e-05 23.9 0.0 14.4 10 3 6 16 16 16 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY24141.1 - 6.8e-14 52.2 3.2 1.6e-05 24.9 0.1 6.6 6 2 0 6 6 6 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY24141.1 - 1.8e-09 37.3 7.1 0.00016 21.1 0.4 7.4 4 4 3 7 7 7 2 WD40-like domain Frtz PF11768.8 CBY24141.1 - 5.2e-09 35.0 0.1 0.13 10.5 0.0 3.8 2 1 0 3 3 3 3 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 CBY24141.1 - 1.7e-08 33.4 0.0 6.9e-05 21.5 0.0 4.4 5 0 0 5 5 5 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 CBY24141.1 - 2.3e-07 29.9 0.0 0.078 11.7 0.0 3.9 3 0 0 3 3 3 3 Nup133 N terminal like BBS2_Mid PF14783.6 CBY24141.1 - 5.1e-06 26.5 0.6 4.6 7.3 0.0 7.4 9 1 1 10 10 8 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 CBY24141.1 - 8.1e-06 24.8 0.0 0.12 10.9 0.0 3.3 3 0 0 3 3 3 2 Nucleoporin Nup120/160 MMS1_N PF10433.9 CBY24141.1 - 0.00017 20.4 0.0 0.057 12.1 0.0 3.6 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Formyl_trans_C PF02911.18 CBY24141.1 - 0.0018 18.5 0.7 3.8 7.8 0.1 4.1 3 1 1 4 4 4 1 Formyl transferase, C-terminal domain Ge1_WD40 PF16529.5 CBY24141.1 - 0.003 16.6 0.7 1.5 7.7 0.0 4.8 4 2 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CBY24141.1 - 0.033 14.2 0.2 23 5.1 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 CBY24141.1 - 0.054 12.8 0.0 2.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FtsK_SpoIIIE_N PF12538.8 CBY24141.1 - 0.11 12.7 0.3 2.6 8.3 0.0 3.0 3 0 0 3 3 3 0 DNA transporter SNAPc_SNAP43 PF09808.9 CBY24142.1 - 3.6e-20 72.7 0.1 3.6e-20 72.7 0.1 2.6 2 1 1 3 3 3 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 AMPKBI PF04739.15 CBY24142.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain SPC22 PF04573.12 CBY24143.1 - 1.2e-49 168.1 0.0 1.4e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit WAC_Acf1_DNA_bd PF10537.9 CBY24144.1 - 5.7e-11 42.8 0.3 2e-10 41.1 0.3 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CBY24144.1 - 6.9e-08 32.9 1.8 2.3e-06 28.0 0.8 3.4 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF1803 PF08820.10 CBY24144.1 - 0.0079 16.2 0.4 8.5 6.5 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1803) RAMP PF04901.13 CBY24144.1 - 0.016 15.2 0.2 0.075 13.0 0.1 2.2 2 0 0 2 2 2 0 Receptor activity modifying family tRNA_lig_kinase PF08303.11 CBY24144.1 - 0.025 14.7 1.5 0.057 13.5 0.3 2.1 2 0 0 2 2 2 0 tRNA ligase kinase domain Glyco_hydro_31 PF01055.26 CBY24145.1 - 2.4e-140 468.6 5.2 3.1e-140 468.3 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CBY24145.1 - 3.2e-16 59.5 0.2 6.9e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 CBY24145.1 - 0.026 14.8 0.1 0.059 13.7 0.1 1.6 1 0 0 1 1 1 0 Galactose mutarotase-like mRNA_cap_enzyme PF01331.19 CBY24148.1 - 1.8e-29 103.0 0.0 3.7e-29 101.9 0.0 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CBY24148.1 - 2.7e-20 73.0 0.1 4.8e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CBY24148.1 - 0.00016 21.4 0.0 0.012 15.3 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Pkinase PF00069.25 CBY24149.1 - 3.6e-17 62.6 0.1 5.4e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24149.1 - 1.3e-10 41.0 0.1 1.8e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Folliculin PF11704.8 CBY24149.1 - 0.099 12.5 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport FtsJ PF01728.19 CBY24150.1 - 0.061 13.4 0.1 0.069 13.3 0.1 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase bZIP_2 PF07716.15 CBY24152.1 - 7.5e-05 22.7 17.8 9.1e-05 22.5 15.3 1.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY24152.1 - 0.0021 18.1 14.3 0.0036 17.4 14.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor LPD30 PF18850.1 CBY24152.1 - 0.021 14.6 2.6 0.13 12.0 2.6 1.9 1 1 0 1 1 1 0 Large polyvalent protein associated domain 30 DUF773 PF05600.12 CBY24152.1 - 0.41 9.3 8.5 0.51 9.0 8.5 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DUF21 PF01595.20 CBY24153.1 - 3.7e-29 101.7 0.0 7.1e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CBY24153.1 - 2e-09 37.7 2.4 1.5e-05 25.4 0.1 2.9 3 0 0 3 3 3 2 CBS domain cNMP_binding PF00027.29 CBY24153.1 - 0.027 14.5 0.0 0.082 13.0 0.0 1.8 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Pkinase PF00069.25 CBY24154.1 - 7.8e-47 159.9 0.0 9.1e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24154.1 - 3.6e-14 52.7 0.0 5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY24154.1 - 3.9e-05 22.6 0.0 6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY24154.1 - 0.00052 20.0 0.0 0.00094 19.2 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY24154.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY24154.1 - 0.0031 16.9 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBY24154.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family S_locus_glycop PF00954.20 CBY24154.1 - 0.016 15.7 0.0 0.034 14.7 0.0 1.6 1 1 0 1 1 1 0 S-locus glycoprotein domain Haspin_kinase PF12330.8 CBY24154.1 - 0.063 12.2 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Sulfatase PF00884.23 CBY24155.1 - 2.3e-57 194.7 0.0 2.8e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY24155.1 - 0.00027 20.6 0.0 0.0042 16.7 0.0 2.4 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 CBY24155.1 - 0.097 12.6 0.1 0.66 9.9 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF1501 PF07394.12 CBY24155.1 - 0.24 10.4 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) UNC80 PF15778.5 CBY24156.1 - 1.7e-18 66.9 0.5 1.4e-14 54.1 0.0 2.7 1 1 1 2 2 2 2 Cation channel complex component UNC80 DUF719 PF05334.13 CBY24156.1 - 0.42 10.8 5.3 0.16 12.2 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF719) Nop53 PF07767.11 CBY24157.1 - 1.8 7.8 8.0 2.4 7.4 8.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) tRNA-synt_1b PF00579.25 CBY24158.1 - 2.7e-21 76.1 0.0 5.8e-21 75.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.20 CBY24158.1 - 1.8e-13 50.4 7.0 1.8e-13 50.4 7.0 1.9 2 0 0 2 2 2 1 WHEP-TRS domain MH2 PF03166.14 CBY24159.1 - 8.5e-70 234.8 1.0 1.2e-69 234.3 1.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CBY24159.1 - 2.6e-40 136.8 1.6 2.6e-40 136.8 1.6 1.6 2 0 0 2 2 2 1 MH1 domain IRF-3 PF10401.9 CBY24159.1 - 0.0026 17.6 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Kindlin_2_N PF18124.1 CBY24160.1 - 4.3e-20 71.7 4.8 1.2e-19 70.3 4.8 1.8 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain FERM_M PF00373.18 CBY24160.1 - 2.1e-16 60.4 3.3 4.7e-15 56.0 3.3 2.8 1 1 0 1 1 1 1 FERM central domain FERM_f0 PF16511.5 CBY24160.1 - 0.038 14.3 1.4 0.11 12.8 0.4 2.4 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM S_locus_glycop PF00954.20 CBY24160.1 - 0.056 14.0 4.5 0.061 13.8 1.8 2.5 2 0 0 2 2 2 0 S-locus glycoprotein domain Pkinase PF00069.25 CBY24161.1 - 2.4e-63 214.0 0.0 3.3e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24161.1 - 6.3e-35 120.7 0.0 1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY24161.1 - 0.00078 18.8 0.1 0.18 11.1 0.0 2.5 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 CBY24161.1 - 0.0015 17.9 0.1 0.0029 17.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY24161.1 - 0.0016 17.4 0.1 0.0016 17.4 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 CBY24161.1 - 0.0026 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY24161.1 - 0.0028 17.6 0.1 0.92 9.4 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family ABC1 PF03109.16 CBY24161.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Seadorna_VP7 PF07387.11 CBY24161.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 XRN_M PF17846.1 CBY24162.1 - 9.1e-144 479.7 0.1 1.5e-143 479.0 0.1 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CBY24162.1 - 4.2e-97 324.3 2.5 8.7e-97 323.3 0.0 2.3 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus HA2 PF04408.23 CBY24163.1 - 1.3e-17 64.0 0.0 2.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) R3H PF01424.22 CBY24163.1 - 6.9e-11 42.0 0.0 1.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain Helicase_C PF00271.31 CBY24163.1 - 2.4e-10 40.7 0.0 6.3e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY24163.1 - 1.1e-07 31.8 0.1 2.4e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY24163.1 - 0.00045 20.5 0.4 0.0025 18.1 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY24163.1 - 0.001 19.4 0.1 0.0035 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CBY24163.1 - 0.0024 17.9 0.1 0.0071 16.4 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit OB_NTP_bind PF07717.16 CBY24163.1 - 0.0027 18.1 0.0 0.0056 17.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_23 PF13476.6 CBY24163.1 - 0.0061 17.1 0.1 0.019 15.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBY24163.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 CBY24163.1 - 0.026 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 CBY24163.1 - 0.046 13.6 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CBY24163.1 - 0.062 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 CBY24163.1 - 0.072 12.9 0.5 8.2 6.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 CBY24163.1 - 0.093 12.8 0.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 CBY24163.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 CBY24163.1 - 0.16 11.7 0.1 0.38 10.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CBY24163.1 - 0.17 12.4 0.5 0.65 10.5 0.5 2.1 1 1 0 1 1 1 0 ABC transporter CBM_14 PF01607.24 CBY24165.1 - 0.0003 20.9 0.5 0.1 12.8 0.1 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain LRR_8 PF13855.6 CBY24167.1 - 1.4e-69 229.8 71.7 3.3e-15 55.6 1.3 7.7 3 2 7 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 CBY24167.1 - 7.7e-24 83.4 62.3 1.4e-08 34.9 1.1 9.4 4 2 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY24167.1 - 5.2e-20 71.7 22.2 4.1e-10 39.7 5.1 3.5 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY24167.1 - 1.4e-11 44.3 24.6 2.1e-06 27.3 4.5 4.6 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 CBY24167.1 - 4.7e-08 32.5 36.3 6.4 7.7 0.0 12.5 13 1 0 13 13 13 4 Leucine Rich Repeat DKNYY PF13644.6 CBY24167.1 - 0.0037 18.0 8.8 0.51 11.1 2.5 2.6 1 1 1 2 2 2 2 DKNYY family LRR_6 PF13516.6 CBY24167.1 - 0.018 15.1 41.9 0.85 9.8 0.2 9.8 12 0 0 12 12 12 0 Leucine Rich repeat Forkhead PF00250.18 CBY24168.1 - 9.9e-18 64.2 0.3 1.8e-16 60.1 0.0 2.3 2 0 0 2 2 2 1 Forkhead domain FlgO PF17680.1 CBY24168.1 - 0.044 13.5 0.1 0.08 12.7 0.1 1.5 1 0 0 1 1 1 0 FlgO protein Plectin PF00681.20 CBY24169.1 - 8.9e-61 201.5 3.8 1.4e-15 56.9 0.0 10.9 9 2 2 11 11 11 8 Plectin repeat CH PF00307.31 CBY24169.1 - 8.6e-48 161.1 0.8 2.6e-24 85.5 0.3 3.1 2 0 0 2 2 2 2 Calponin homology (CH) domain SH3_10 PF17902.1 CBY24169.1 - 6.6e-09 35.7 0.6 3.8e-08 33.3 0.1 2.5 2 0 0 2 2 2 1 SH3 domain CAMSAP_CH PF11971.8 CBY24169.1 - 1.2e-07 31.4 0.1 0.0043 16.8 0.0 3.3 3 0 0 3 3 3 2 CAMSAP CH domain Spectrin PF00435.21 CBY24169.1 - 0.0048 17.4 7.4 0.0048 17.4 7.4 13.8 10 2 6 16 16 16 3 Spectrin repeat Tetrabrachion PF11401.8 CBY24169.1 - 0.077 13.0 0.1 0.44 10.6 0.0 2.4 2 0 0 2 2 2 0 Tetrabrachion CH_2 PF06294.11 CBY24169.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.0 3 0 0 3 3 3 0 CH-like domain in sperm protein Sulfotransfer_2 PF03567.14 CBY24171.1 - 4.1e-14 53.1 1.8 6.3e-14 52.5 1.8 1.2 1 0 0 1 1 1 1 Sulfotransferase family TSP_1 PF00090.19 CBY24172.1 - 0.00093 19.4 4.6 0.00093 19.4 4.6 10.6 10 0 0 10 10 10 5 Thrombospondin type 1 domain Pkinase PF00069.25 CBY24173.1 - 1.3e-64 218.1 0.0 1.9e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24173.1 - 2.6e-35 122.0 0.0 3.9e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CBY24173.1 - 5.1e-10 39.4 0.1 1.6e-05 25.0 0.0 2.9 3 0 0 3 3 3 2 POLO box duplicated region Pkinase_fungal PF17667.1 CBY24173.1 - 3.2e-08 32.8 0.0 5.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY24173.1 - 0.00021 21.3 0.0 0.00054 20.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY24173.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY24173.1 - 0.0039 16.6 0.2 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Gal-3-0_sulfotr PF06990.11 CBY24174.1 - 3.3e-66 223.8 0.3 4.3e-66 223.4 0.3 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_3 PF13469.6 CBY24174.1 - 0.0065 16.9 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CBY24174.1 - 0.0067 16.4 0.3 2.4 8.0 0.0 2.8 2 1 0 2 2 2 2 Sulfotransferase family Ank_2 PF12796.7 CBY24175.1 - 1.4e-42 144.1 7.7 2.2e-17 63.4 0.1 5.1 3 2 3 6 6 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY24175.1 - 1.7e-28 98.6 1.3 9.6e-10 38.8 0.2 6.3 2 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24175.1 - 5.6e-26 87.8 5.6 0.00069 19.9 0.0 8.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 CBY24175.1 - 1.1e-25 89.4 4.2 3.1e-05 24.2 0.0 7.3 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 CBY24175.1 - 2.9e-22 78.0 5.5 0.00011 22.5 0.1 9.1 9 0 0 9 9 9 5 Ankyrin repeat Rhomboid PF01694.22 CBY24176.1 - 1.9e-31 109.1 12.0 1.9e-31 109.1 12.0 1.8 1 1 1 2 2 2 1 Rhomboid family DUF4153 PF13687.6 CBY24176.1 - 2.2 7.9 8.4 6.1 6.4 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4153) Ribosomal_S18 PF01084.20 CBY24177.1 - 4.8e-06 26.7 0.0 9.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 zf-C2H2 PF00096.26 CBY24178.1 - 1.3e-08 34.8 17.3 0.0075 16.7 1.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY24178.1 - 6.5e-05 23.4 15.3 0.022 15.6 1.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY24178.1 - 0.0015 18.8 1.0 0.0015 18.8 1.0 3.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY24178.1 - 0.005 17.1 2.9 0.2 12.0 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY24178.1 - 0.008 16.6 1.6 0.008 16.6 1.6 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY24178.1 - 0.04 13.9 7.0 0.16 12.0 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY24178.1 - 5.6 6.8 8.7 3 7.7 3.1 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type BNIP2 PF12496.8 CBY24179.1 - 7.9 6.9 6.3 7.9 6.9 3.6 2.5 1 1 2 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Sgf11 PF08209.11 CBY24180.1 - 1.3e-15 56.6 0.2 2.7e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DZR PF12773.7 CBY24180.1 - 0.02 14.9 0.6 0.046 13.7 0.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CBY24180.1 - 0.92 9.7 3.6 0.84 9.8 0.4 2.5 3 0 0 3 3 3 0 Zinc ribbon domain DnaJ PF00226.31 CBY24181.1 - 6.3e-25 87.1 5.8 1.1e-24 86.3 5.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CBY24181.1 - 4.8e-22 78.6 0.1 7.3e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBY24181.1 - 1.6e-12 47.6 15.5 3.7e-12 46.4 15.5 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBY24181.1 - 0.00018 21.4 17.3 0.0012 18.8 5.0 3.4 1 1 2 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein GRP PF07172.11 CBY24181.1 - 0.017 15.8 5.5 0.047 14.4 5.5 1.8 1 0 0 1 1 1 0 Glycine rich protein family Mu-like_Pro PF10123.9 CBY24181.1 - 0.097 12.2 0.3 0.14 11.7 0.3 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein zf-RING_10 PF16685.5 CBY24181.1 - 1.2 9.3 6.6 0.4 10.9 0.8 2.7 1 1 0 2 2 2 0 zinc RING finger of MSL2 FdhE PF04216.12 CBY24181.1 - 4.9 6.9 7.5 1.1 9.1 4.0 1.5 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation DUF3417 PF11897.8 CBY24182.1 - 3.1 8.3 11.5 0.081 13.4 1.1 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF3417) GATA PF00320.27 CBY24184.1 - 3.8e-12 45.6 5.6 1.1e-11 44.1 5.6 1.9 1 0 0 1 1 1 1 GATA zinc finger BAH PF01426.18 CBY24184.1 - 2.8e-10 40.1 0.6 2e-09 37.4 0.6 2.2 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.24 CBY24184.1 - 0.00028 21.6 0.1 0.00086 20.0 0.1 1.9 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 CBY24184.1 - 0.0024 17.7 0.1 0.0066 16.3 0.1 1.7 1 0 0 1 1 1 1 Myb DNA-binding like zf-UDP PF14569.6 CBY24184.1 - 0.022 14.9 0.2 0.061 13.4 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Myb_DNA-bind_6 PF13921.6 CBY24184.1 - 0.023 15.0 0.4 0.18 12.1 0.1 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CBY24184.1 - 0.15 12.3 0.8 0.56 10.4 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain TUDOR PF00567.24 CBY24185.1 - 5.7e-54 181.3 0.1 4.2e-16 59.1 0.0 5.6 5 1 0 5 5 5 5 Tudor domain Methyltransf_28 PF02636.17 CBY24185.1 - 0.039 13.6 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Pmp3 PF01679.17 CBY24186.1 - 0.089 13.0 2.0 0.94 9.7 0.1 2.5 2 0 0 2 2 2 0 Proteolipid membrane potential modulator TPR_2 PF07719.17 CBY24187.1 - 5.8e-06 26.0 0.3 0.0027 17.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY24187.1 - 9.1e-06 25.3 0.5 0.0006 19.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY24187.1 - 0.012 16.4 0.1 0.11 13.3 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 CBY24187.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBY24187.1 - 0.016 15.7 0.2 0.22 12.0 0.2 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY24187.1 - 0.027 14.6 0.6 0.086 13.0 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY24187.1 - 0.049 13.9 0.5 4 7.8 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat rhaM PF05336.13 CBY24187.1 - 0.65 10.1 2.6 0.74 9.9 0.3 2.0 2 0 0 2 2 2 0 L-rhamnose mutarotase Methyltransf_25 PF13649.6 CBY24188.1 - 1.1e-12 48.5 0.1 3.3e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY24188.1 - 4.6e-12 46.0 0.2 1.1e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBY24188.1 - 1.4e-11 44.4 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CBY24188.1 - 3.9e-09 37.0 0.0 1.8e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY24188.1 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY24188.1 - 2.4e-05 25.0 0.1 6.3e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 CBY24188.1 - 3e-05 23.6 0.1 4.9e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CBY24188.1 - 6.2e-05 23.0 0.1 0.00011 22.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBY24188.1 - 9e-05 21.5 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 CBY24188.1 - 0.00014 21.2 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 CBY24188.1 - 0.0026 17.9 0.4 0.0078 16.3 0.4 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 CBY24188.1 - 0.0056 16.7 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CBY24188.1 - 0.007 16.1 0.1 0.018 14.8 0.1 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CBY24188.1 - 0.0087 15.8 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 CBY24188.1 - 0.028 15.4 0.0 0.049 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 CBY24188.1 - 0.038 13.8 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Ank_2 PF12796.7 CBY24189.1 - 6.1e-31 106.8 3.4 2e-16 60.4 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CBY24189.1 - 6.1e-20 70.7 0.5 1.4e-05 25.3 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 CBY24189.1 - 3.2e-18 65.9 0.3 3.7e-10 40.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24189.1 - 7.4e-14 50.5 0.0 4.9e-06 26.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CBY24189.1 - 7.1e-13 48.5 0.2 1e-08 35.3 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Tetraspanin PF00335.20 CBY24189.1 - 0.18 11.5 0.2 0.41 10.3 0.2 1.5 1 0 0 1 1 1 0 Tetraspanin family TRM PF02005.16 CBY24190.1 - 7.4e-111 371.0 0.0 9.6e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 CBY24190.1 - 0.091 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Innexin PF00876.18 CBY24193.1 - 0.00017 21.0 0.2 0.0002 20.8 0.2 1.1 1 0 0 1 1 1 1 Innexin Pox_I6 PF04595.13 CBY24193.1 - 0.06 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family DUF2852 PF11014.8 CBY24193.1 - 1.1 9.4 3.6 11 6.2 2.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) ADIP PF11559.8 CBY24194.1 - 0.03 14.4 1.7 0.03 14.4 1.7 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3226 PF11536.8 CBY24194.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) DUF4558 PF15104.6 CBY24196.1 - 0.082 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) Peptidase_M10 PF00413.24 CBY24198.1 - 7e-34 116.9 0.6 1.5e-33 115.9 0.6 1.6 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 CBY24198.1 - 2.4e-18 65.8 1.2 3.2e-05 23.8 0.1 4.4 4 0 0 4 4 4 4 Hemopexin Reprolysin_5 PF13688.6 CBY24198.1 - 0.00051 20.3 0.2 0.00093 19.4 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 CBY24198.1 - 0.0012 17.9 0.4 0.0018 17.3 0.4 1.2 1 0 0 1 1 1 1 Peptidase M66 Metallopep PF12044.8 CBY24198.1 - 0.0014 17.4 0.0 0.002 16.8 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M54 PF07998.11 CBY24198.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_4 PF13583.6 CBY24198.1 - 0.07 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CBY24198.1 - 0.096 11.9 1.0 0.15 11.2 1.0 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 CBY24198.1 - 0.11 13.0 1.4 0.2 12.2 1.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MFS_1 PF07690.16 CBY24199.1 - 1.1e-34 119.9 27.0 1.4e-34 119.6 27.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4133 PF13571.6 CBY24199.1 - 0.024 15.0 0.2 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) DUF2070 PF09843.9 CBY24199.1 - 0.13 10.6 1.2 0.15 10.3 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PRC2_HTH_1 PF18118.1 CBY24200.1 - 0.012 16.4 1.6 0.018 15.9 1.6 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain PAX PF00292.18 CBY24201.1 - 4.1e-59 198.0 0.3 4.6e-59 197.8 0.3 1.0 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CBY24201.1 - 1.4e-06 27.9 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CBY24201.1 - 4e-05 23.5 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 CBY24201.1 - 0.00029 21.4 0.0 0.02 15.5 0.0 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 CBY24201.1 - 0.00058 19.9 0.0 0.00085 19.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 CBY24201.1 - 0.0033 17.1 0.1 0.0058 16.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 CBY24201.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 CBY24201.1 - 0.068 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 CBY24201.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 MarR family SRP72 PF08492.12 CBY24202.1 - 0.02 15.3 0.7 0.12 12.8 0.2 2.2 2 0 0 2 2 2 0 SRP72 RNA-binding domain Astacin PF01400.24 CBY24203.1 - 1.1e-35 123.0 0.1 1.4e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Kelch_1 PF01344.25 CBY24204.1 - 0.077 12.6 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Pyridoxal_deC PF00282.19 CBY24205.1 - 5.1e-12 45.2 0.0 1.7e-11 43.5 0.0 1.8 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CBY24205.1 - 3.1e-05 23.1 0.0 6.8e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBY24205.1 - 0.00015 21.2 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Trypsin PF00089.26 CBY24206.1 - 8.1e-19 68.3 0.5 1.8e-18 67.2 0.5 1.5 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY24206.1 - 0.0054 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) GUN4_N PF16416.5 CBY24206.1 - 0.057 13.4 0.1 0.18 11.8 0.0 1.9 1 1 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal Trefoil PF00088.18 CBY24206.1 - 0.43 10.5 16.0 0.1 12.5 0.7 4.2 3 1 0 3 3 3 0 Trefoil (P-type) domain polyprenyl_synt PF00348.17 CBY24207.1 - 0.00097 18.3 0.2 0.0019 17.3 0.2 1.5 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 CBY24207.1 - 0.029 14.0 0.2 0.074 12.6 0.1 1.8 1 1 1 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 EF-hand_6 PF13405.6 CBY24208.1 - 4.7e-12 44.8 4.7 3.9e-05 23.2 0.2 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY24208.1 - 2.3e-11 42.4 15.3 5.9e-06 25.5 0.6 4.5 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 CBY24208.1 - 1.1e-08 34.1 3.6 0.00014 21.1 0.3 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY24208.1 - 1.2e-07 31.5 15.2 8.7e-06 25.5 0.9 4.5 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 CBY24208.1 - 3.3e-07 30.6 8.4 0.0023 18.3 0.4 3.8 2 2 2 4 4 4 3 EF-hand domain pair DUF1461 PF07314.11 CBY24208.1 - 0.0042 17.0 1.2 0.0042 17.0 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1461) Z1 PF10593.9 CBY24208.1 - 0.016 14.7 1.1 0.037 13.5 1.1 1.6 1 0 0 1 1 1 0 Z1 domain Acetyltransf_13 PF13880.6 CBY24209.1 - 7.3e-14 51.5 0.0 1.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.25 CBY24209.1 - 0.00042 20.5 0.0 0.00084 19.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY24209.1 - 0.0084 16.5 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-ribbon_3 PF13248.6 CBY24209.1 - 0.083 12.3 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Ank_2 PF12796.7 CBY24210.1 - 2.3e-20 72.9 0.1 6.8e-16 58.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY24210.1 - 9.1e-17 61.2 3.1 1.1e-08 35.5 0.1 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24210.1 - 9.8e-17 59.4 0.3 1.5e-05 25.0 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 CBY24210.1 - 3.7e-16 58.7 1.4 4.9e-08 33.1 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 CBY24210.1 - 8.4e-16 57.8 2.7 5.8e-07 29.7 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) WSD PF15613.6 CBY24211.1 - 1e-17 64.4 0.2 3.4e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 CBY24211.1 - 2.5e-11 43.3 12.3 2.7e-11 43.2 10.5 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CBY24211.1 - 0.0041 16.6 4.0 0.0041 16.6 4.0 2.2 2 0 0 2 2 2 1 PHD-finger zf-RRPl_C4 PF17026.5 CBY24211.1 - 0.17 12.0 5.8 0.63 10.2 5.8 2.0 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_2 PF03107.16 CBY24211.1 - 0.35 11.2 9.6 0.04 14.2 4.6 2.0 2 0 0 2 2 2 0 C1 domain DZR PF12773.7 CBY24211.1 - 6.1 7.0 9.0 8.8 6.4 0.5 2.4 1 1 2 3 3 2 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 CBY24211.1 - 9.1 6.4 8.9 31 4.7 8.9 1.9 1 1 0 1 1 1 0 Transposase zinc-binding domain MH2 PF03166.14 CBY24212.1 - 2.8e-46 158.1 0.1 4.9e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CBY24212.1 - 7.4e-11 42.2 0.3 1.6e-10 41.1 0.3 1.6 1 0 0 1 1 1 1 MH1 domain C2 PF00168.30 CBY24213.1 - 6.2e-53 177.4 4.9 1.5e-26 92.7 0.2 2.7 3 0 0 3 3 3 2 C2 domain TMEM52 PF14979.6 CBY24213.1 - 0.0025 17.7 1.0 0.0053 16.7 1.0 1.5 1 0 0 1 1 1 1 Transmembrane 52 CEP76-C2 PF15627.6 CBY24213.1 - 0.0064 16.1 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 1 CEP76 C2 domain TSGA13 PF14994.6 CBY24213.1 - 0.014 14.8 0.6 0.033 13.6 0.6 1.5 1 0 0 1 1 1 0 Testis-specific gene 13 protein PTEN_C2 PF10409.9 CBY24213.1 - 0.016 15.0 0.9 1 9.1 0.0 2.9 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein Transglut_C PF00927.22 CBY24213.1 - 0.019 15.1 0.3 7.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Cadherin_C_2 PF16492.5 CBY24213.1 - 0.021 15.6 0.0 0.057 14.2 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Shisa PF13908.6 CBY24213.1 - 0.021 15.1 0.3 0.041 14.1 0.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.6 CBY24213.1 - 0.04 12.3 1.0 0.79 8.1 0.2 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EphA2_TM PF14575.6 CBY24213.1 - 0.044 14.7 1.8 0.14 13.1 1.8 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF997 PF06196.12 CBY24213.1 - 0.052 13.6 0.2 0.092 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) PAG PF15347.6 CBY24213.1 - 0.059 12.4 0.2 0.092 11.7 0.2 1.3 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched TMIE PF16038.5 CBY24213.1 - 0.15 12.0 5.0 0.12 12.2 2.4 2.3 2 0 0 2 2 2 0 TMIE protein TRP PF06011.12 CBY24213.1 - 0.19 10.4 0.1 0.29 9.8 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel LYRIC PF15686.5 CBY24213.1 - 0.38 10.3 6.9 0.024 14.2 1.4 1.7 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family MAP17 PF15807.5 CBY24213.1 - 0.65 10.2 5.2 0.13 12.5 1.4 1.9 2 1 0 2 2 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LRR_8 PF13855.6 CBY24214.1 - 2e-29 101.1 30.3 8.6e-10 38.2 4.3 5.0 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CBY24214.1 - 3e-18 65.6 27.1 0.00013 22.3 1.2 6.6 4 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY24214.1 - 4.1e-08 33.3 8.8 0.0024 17.8 0.6 3.3 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 CBY24214.1 - 8.9e-08 31.6 3.6 8.9e-08 31.6 3.6 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 CBY24214.1 - 3.7e-06 26.6 13.8 0.0005 19.6 1.1 4.1 1 1 4 5 5 5 4 Leucine-rich repeat Cadherin_C_2 PF16492.5 CBY24214.1 - 0.00037 21.2 0.1 0.001 19.8 0.1 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal LRR_6 PF13516.6 CBY24214.1 - 0.00071 19.4 17.4 1 9.6 0.2 7.2 7 0 0 7 7 7 3 Leucine Rich repeat DUF4690 PF15756.5 CBY24214.1 - 0.022 15.3 2.1 0.059 14.0 2.1 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 CBY24214.1 - 0.042 14.7 0.1 0.077 13.9 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4789 PF16033.5 CBY24214.1 - 0.11 13.1 0.3 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4789) LRR_1 PF00560.33 CBY24214.1 - 0.14 12.8 26.2 16 6.5 0.5 9.2 8 3 1 9 9 9 0 Leucine Rich Repeat Adeno_E3_CR2 PF02439.15 CBY24214.1 - 0.33 10.8 4.4 0.61 9.9 4.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Iso_dh PF00180.20 CBY24216.1 - 6.3e-06 25.6 0.0 7.3e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DeoC PF01791.9 CBY24218.1 - 1.6e-26 93.4 0.5 2e-26 93.1 0.5 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Iso_dh PF00180.20 CBY24219.1 - 2.6e-61 207.7 0.1 3.9e-61 207.1 0.1 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DRY_EERY PF09750.9 CBY24220.1 - 5.8e-24 84.9 0.2 5.8e-24 84.9 0.2 3.1 3 1 0 3 3 3 1 Alternative splicing regulator Surp PF01805.20 CBY24220.1 - 7e-12 45.2 1.9 2.3e-09 37.1 0.3 2.6 2 0 0 2 2 2 2 Surp module FlgM PF04316.13 CBY24220.1 - 0.022 15.1 0.0 0.094 13.1 0.0 2.1 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Oxysterol_BP PF01237.18 CBY24221.1 - 2.1e-114 382.2 2.4 3.9e-114 381.4 2.4 1.4 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3042 PF11240.8 CBY24221.1 - 0.94 9.5 3.4 1.8 8.7 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) SAP PF02037.27 CBY24222.1 - 0.15 11.8 1.5 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 SAP domain kleA_kleC PF17383.2 CBY24222.1 - 0.43 10.9 4.2 7.4 7.0 2.6 2.8 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A KIP1 PF07765.12 CBY24222.1 - 7.9 6.7 9.0 0.58 10.3 2.4 2.5 2 1 1 3 3 3 0 KIP1-like protein DUF4028 PF13220.6 CBY24223.1 - 0.024 14.4 0.9 0.027 14.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) FHA PF00498.26 CBY24224.1 - 4e-16 59.1 0.1 1.2e-15 57.6 0.1 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CBY24224.1 - 1.8e-07 31.4 0.0 2.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DZF PF07528.14 CBY24225.1 - 6.1e-47 160.3 0.0 2.4e-46 158.4 0.0 2.0 1 1 0 1 1 1 1 DZF domain zf-C2H2_jaz PF12171.8 CBY24225.1 - 1.2e-05 25.5 3.0 2.2e-05 24.6 3.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY24225.1 - 1.5e-05 25.2 0.7 2.8e-05 24.4 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type dsrm PF00035.26 CBY24225.1 - 0.059 14.1 0.0 0.19 12.4 0.0 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding motif Rhomboid_N PF12122.8 CBY24225.1 - 0.078 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease RNB PF00773.19 CBY24226.1 - 4.5e-101 338.4 0.0 7e-101 337.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CBY24226.1 - 2.4e-15 56.3 0.0 1.5e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CBY24226.1 - 0.00099 19.4 0.0 0.0036 17.6 0.0 1.9 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 CBY24226.1 - 0.0011 19.1 0.2 0.15 12.2 0.0 3.2 3 0 0 3 3 3 1 Cold shock domain Rrp44_CSD1 PF17216.3 CBY24226.1 - 0.0015 18.2 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Arg_repressor PF01316.21 CBY24226.1 - 0.63 9.8 2.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain PP2C PF00481.21 CBY24228.1 - 4.7e-67 226.3 0.1 6.9e-67 225.8 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 CBY24228.1 - 5.3e-23 81.3 0.2 1.7e-22 79.7 0.1 1.8 2 0 0 2 2 2 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 CBY24228.1 - 2.7e-06 27.2 0.0 1.3e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C 4_1_CTD PF05902.13 CBY24228.1 - 0.08 13.0 0.4 0.18 11.9 0.4 1.6 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Lipase_GDSL PF00657.22 CBY24228.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase FH2 PF02181.23 CBY24229.1 - 4.2e-77 259.8 17.8 4.2e-77 259.8 17.8 2.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CBY24229.1 - 4.9e-40 137.1 0.5 4.9e-40 137.1 0.5 2.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CBY24229.1 - 1.8e-36 125.6 0.6 1.8e-36 125.6 0.6 3.5 3 1 0 3 3 3 1 Diaphanous FH3 Domain Cas6 PF09559.10 CBY24229.1 - 0.026 14.5 0.3 0.34 10.8 0.1 2.7 2 0 0 2 2 2 0 Cas6 Crispr UvrC_HhH_N PF08459.11 CBY24229.1 - 0.059 13.3 1.0 0.24 11.3 0.1 2.5 2 1 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal DUF5071 PF16804.5 CBY24229.1 - 0.078 13.2 1.7 0.8 10.0 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5071) Mito_fiss_reg PF05308.11 CBY24229.1 - 0.23 11.5 10.0 0.071 13.2 5.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator TMF_TATA_bd PF12325.8 CBY24229.1 - 0.7 10.1 42.5 0.087 13.1 14.7 5.1 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 CBY24229.1 - 3.1 7.8 17.8 3.9 7.5 4.6 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ABC_tran PF00005.27 CBY24229.1 - 4.8 7.7 10.4 0.38 11.3 0.4 3.5 3 1 0 3 3 3 0 ABC transporter Chromo PF00385.24 CBY24230.1 - 1.2e-16 60.3 0.2 2e-15 56.4 0.2 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CBY24230.1 - 1.3e-07 31.6 0.0 0.0004 20.4 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain PRMT5 PF05185.16 CBY24231.1 - 7.8e-10 38.9 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.14 CBY24231.1 - 9.2e-09 35.1 0.0 1.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CBY24231.1 - 2.4e-08 33.7 0.0 3.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CBY24231.1 - 2.8e-08 34.4 0.0 1.7e-07 31.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY24231.1 - 5.4e-06 27.0 0.0 1.6e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY24231.1 - 9e-06 25.5 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY24231.1 - 1.8e-05 24.6 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBY24231.1 - 0.00011 21.3 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5_C PF17286.2 CBY24231.1 - 0.00038 20.4 0.2 0.00082 19.3 0.2 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_12 PF08242.12 CBY24231.1 - 0.0011 19.7 0.0 0.006 17.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBY24231.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBY24231.1 - 0.0028 17.0 0.1 0.0043 16.4 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 CBY24231.1 - 0.0029 17.3 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TehB PF03848.14 CBY24231.1 - 0.0038 16.7 0.1 0.0061 16.0 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.12 CBY24231.1 - 0.0039 16.3 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase N6_N4_Mtase PF01555.18 CBY24231.1 - 0.011 15.5 0.1 0.1 12.3 0.0 2.2 1 1 0 2 2 2 0 DNA methylase Methyltransf_32 PF13679.6 CBY24231.1 - 0.024 14.6 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CBY24231.1 - 0.042 13.6 0.2 0.072 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4985 PF16373.5 CBY24231.1 - 0.053 14.0 0.6 0.52 10.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function RrnaAD PF00398.20 CBY24231.1 - 0.095 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GidB PF02527.15 CBY24231.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G ANTH PF07651.16 CBY24232.1 - 1.2e-64 218.0 0.3 1.2e-64 218.0 0.3 1.9 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 CBY24232.1 - 1.5e-13 50.9 0.0 3.1e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 ENTH domain Transferrin PF00405.17 CBY24232.1 - 0.036 13.2 0.0 0.92 8.6 0.0 2.2 1 1 1 2 2 2 0 Transferrin ASFV_J13L PF05568.11 CBY24232.1 - 2.2 8.0 5.8 15 5.2 0.2 3.0 2 1 1 3 3 3 0 African swine fever virus J13L protein PglL_A PF15864.5 CBY24233.1 - 0.024 14.3 1.4 0.024 14.3 1.4 2.2 2 0 0 2 2 2 0 Protein glycosylation ligase SET PF00856.28 CBY24234.1 - 1e-08 35.8 0.8 2.6e-08 34.4 0.0 2.0 2 1 0 2 2 2 1 SET domain Pkinase PF00069.25 CBY24235.1 - 1.4e-61 208.2 0.0 3.8e-61 206.8 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24235.1 - 3.6e-36 124.8 0.0 8.5e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 CBY24235.1 - 4.2e-24 84.4 30.3 2.5e-10 40.3 9.0 4.2 3 0 0 3 3 3 3 Hr1 repeat Pkinase_C PF00433.24 CBY24235.1 - 4.5e-12 46.5 2.2 1.4e-11 44.9 2.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CBY24235.1 - 1.1e-05 24.9 1.0 5.2e-05 22.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Uds1 PF15456.6 CBY24235.1 - 0.0051 17.0 5.4 0.0051 17.0 5.4 4.2 4 0 0 4 4 4 1 Up-regulated During Septation DUF842 PF05811.13 CBY24235.1 - 3.7 7.3 12.7 9.8 5.9 0.8 3.4 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Pkinase PF00069.25 CBY24237.1 - 4.7e-49 167.1 0.0 6.9e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24237.1 - 9.7e-48 162.7 0.0 1.6e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY24237.1 - 0.00076 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY24237.1 - 0.0046 16.3 0.1 0.66 9.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 CBY24237.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY24237.1 - 0.032 13.0 1.1 0.063 12.1 0.0 1.9 3 0 0 3 3 3 0 Fungal protein kinase HAND PF09110.11 CBY24237.1 - 0.063 14.0 0.0 0.18 12.6 0.0 1.7 1 0 0 1 1 1 0 HAND Dpy-30 PF05186.13 CBY24241.1 - 8.2e-12 44.6 0.3 2e-11 43.4 0.3 1.6 1 1 0 1 1 1 1 Dpy-30 motif DUF3453 PF11935.8 CBY24241.1 - 0.04 13.5 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Ank_2 PF12796.7 CBY24242.1 - 8.3e-26 90.4 3.1 1.3e-12 48.1 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY24242.1 - 1e-23 83.1 2.2 2.5e-06 27.7 0.2 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY24242.1 - 1e-19 70.6 0.5 0.00018 22.0 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24242.1 - 1.4e-17 62.0 1.0 0.1 13.2 0.1 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CBY24242.1 - 1.1e-16 60.4 1.7 0.044 14.3 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Glyco_transf_22 PF03901.17 CBY24243.1 - 8.5e-76 255.8 36.7 1e-75 255.6 36.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Orai-1 PF07856.12 CBY24244.1 - 2.1e-48 164.3 2.6 2.8e-48 163.9 2.6 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity Coatomer_WDAD PF04053.14 CBY24245.1 - 5.1e-149 497.1 0.0 9.3e-149 496.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CBY24245.1 - 9.4e-43 143.4 10.1 5e-09 36.6 0.1 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY24245.1 - 3.7e-08 33.5 2.0 0.091 13.1 0.0 6.6 3 2 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY24245.1 - 0.049 12.3 0.8 3.2 6.3 0.0 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 MetallophosC PF16370.5 CBY24245.1 - 0.076 13.3 0.1 0.56 10.4 0.0 2.4 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Prominin PF05478.11 CBY24247.1 - 3.2e-127 425.6 4.5 9.2e-126 420.8 4.5 2.0 1 1 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.12 CBY24247.1 - 0.0013 18.8 0.3 0.0013 18.8 0.3 4.4 3 2 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 CBY24247.1 - 0.0082 16.4 1.7 6.5 7.1 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF5082) SF-assemblin PF06705.11 CBY24247.1 - 0.05 12.9 2.1 4.8 6.4 0.0 3.2 3 0 0 3 3 3 0 SF-assemblin/beta giardin DUF1664 PF07889.12 CBY24247.1 - 0.067 13.2 4.8 4.1 7.5 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) GRAS PF03514.14 CBY24247.1 - 0.092 11.7 0.2 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 GRAS domain family XhlA PF10779.9 CBY24247.1 - 0.49 10.6 6.4 15 5.8 0.0 4.2 4 0 0 4 4 4 0 Haemolysin XhlA Helo_like_N PF17111.5 CBY24247.1 - 0.75 9.1 7.1 0.37 10.1 0.8 3.3 3 1 1 4 4 4 0 Fungal N-terminal domain of STAND proteins CENP-F_leu_zip PF10473.9 CBY24247.1 - 0.77 9.8 5.0 0.81 9.7 0.9 2.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 CBY24247.1 - 1.3 9.0 8.7 0.44 10.5 1.1 3.2 4 0 0 4 4 4 0 Prefoldin subunit Prefoldin PF02996.17 CBY24247.1 - 1.8 8.5 6.2 7.7 6.5 0.2 3.7 4 0 0 4 4 4 0 Prefoldin subunit TBCC_N PF16752.5 CBY24247.1 - 6.1 7.3 7.3 66 4.0 0.2 4.4 4 1 1 5 5 5 0 Tubulin-specific chaperone C N-terminal domain DASH_Duo1 PF08651.10 CBY24247.1 - 7.2 6.5 8.5 3.8 7.3 0.1 4.5 6 0 0 6 6 6 0 DASH complex subunit Duo1 Atg8 PF02991.16 CBY24248.1 - 2.1e-47 159.6 0.1 2.4e-47 159.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBY24248.1 - 1.3e-07 31.9 0.0 1.6e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF5641 PF18701.1 CBY24248.1 - 0.071 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5641) EF-hand_1 PF00036.32 CBY24249.1 - 1.6e-22 77.3 6.3 3.2e-07 29.4 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY24249.1 - 1.4e-21 76.7 5.7 1.2e-13 51.3 0.6 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CBY24249.1 - 2.5e-20 70.6 1.1 5.7e-05 22.7 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CBY24249.1 - 1.5e-14 53.6 6.7 2.2e-06 27.4 0.3 4.1 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY24249.1 - 2e-13 49.1 5.3 0.00012 21.4 0.3 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBY24249.1 - 7.2e-05 23.0 0.0 0.0046 17.2 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBY24249.1 - 8.2e-05 22.5 2.3 0.13 12.2 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY24249.1 - 0.0011 19.3 2.9 0.2 12.0 0.5 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CBY24249.1 - 0.0036 17.3 3.2 5.9 6.8 0.1 3.6 1 1 2 4 4 4 1 Caleosin related protein Nro1 PF12753.7 CBY24249.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 S10_plectin PF03501.15 CBY24249.1 - 0.036 14.1 0.0 0.071 13.2 0.0 1.6 1 1 0 1 1 1 0 Plectin/S10 domain NADPH_Ox PF08414.10 CBY24249.1 - 0.12 12.7 1.2 2.6 8.4 0.1 2.5 1 1 2 3 3 3 0 Respiratory burst NADPH oxidase EF-hand_2 PF09068.11 CBY24249.1 - 0.15 12.2 0.0 3 8.0 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_14 PF17959.1 CBY24249.1 - 0.18 12.1 1.5 4.3 7.7 0.0 2.9 3 1 0 3 3 3 0 EF-hand domain Glycos_trans_3N PF02885.17 CBY24249.1 - 0.2 11.5 0.2 3.3 7.6 0.0 2.9 3 1 0 3 3 3 0 Glycosyl transferase family, helical bundle domain CBF PF03914.17 CBY24251.1 - 7.9e-10 39.0 0.2 1.2e-09 38.4 0.2 1.2 1 0 0 1 1 1 1 CBF/Mak21 family zf-CCCH_7 PF18586.1 CBY24253.1 - 0.024 15.0 0.1 0.069 13.5 0.1 1.9 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 T3SS_needle_F PF09392.10 CBY24253.1 - 0.031 14.5 1.3 0.14 12.4 1.3 2.2 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Pro_Al_protease PF02983.14 CBY24253.1 - 0.17 12.0 0.0 0.17 12.0 0.0 2.5 3 0 0 3 3 3 0 Alpha-lytic protease prodomain DnaJ_CXXCXGXG PF00684.19 CBY24257.1 - 0.016 15.6 12.6 3 8.3 13.1 3.0 1 1 0 1 1 1 0 DnaJ central domain VWA_N2 PF16164.5 CBY24257.1 - 2.8 8.1 9.5 0.29 11.3 2.0 2.3 2 0 0 2 2 2 0 VWA N-terminal His_kinase PF06580.13 CBY24258.1 - 0.052 13.9 0.1 0.56 10.6 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase YihI PF04220.12 CBY24258.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) MA3 PF02847.17 CBY24259.1 - 3.9e-34 117.0 1.5 2.1e-20 72.8 0.3 2.2 2 0 0 2 2 2 2 MA3 domain SMN PF06003.12 CBY24260.1 - 0.3 10.3 6.5 0.58 9.4 6.5 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ferlin_C PF16165.5 CBY24260.1 - 0.44 10.5 2.4 0.69 9.8 2.4 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Med19 PF10278.9 CBY24260.1 - 2.4 8.1 10.1 3.7 7.4 10.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 EGF PF00008.27 CBY24261.1 - 1.1e-11 44.8 23.6 5.3e-07 29.8 5.3 6.0 5 2 1 6 6 6 2 EGF-like domain Astacin PF01400.24 CBY24261.1 - 3.7e-08 33.2 0.0 7.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY24261.1 - 1.2e-06 28.7 27.9 2.1e-05 24.6 16.3 5.4 5 1 0 5 5 5 2 Low-density lipoprotein receptor domain class A hEGF PF12661.7 CBY24261.1 - 2.6e-05 24.7 16.2 0.00061 20.3 2.2 6.7 8 0 0 8 8 8 2 Human growth factor-like EGF EGF_2 PF07974.13 CBY24261.1 - 0.032 14.6 13.5 0.032 14.6 13.5 5.2 5 1 0 5 5 5 0 EGF-like domain Neur_chan_LBD PF02931.23 CBY24262.1 - 1.8e-37 128.9 0.1 2.6e-37 128.4 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY24262.1 - 7.6e-22 78.5 1.1 1.1e-21 78.0 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1129 PF06570.11 CBY24262.1 - 0.027 14.0 0.1 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Thiolase_N PF00108.23 CBY24264.1 - 6e-73 245.4 0.2 9.4e-73 244.8 0.0 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY24264.1 - 1.9e-36 124.4 0.1 4.3e-36 123.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY24264.1 - 1.2e-05 25.0 0.5 0.00016 21.3 0.3 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CBY24264.1 - 1 9.3 6.7 7.2 6.5 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1308 PF07000.11 CBY24265.1 - 5.4e-45 153.3 1.1 5.4e-45 153.3 1.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 CBY24265.1 - 1.5e-16 60.4 0.3 2.9e-16 59.4 0.1 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5614) DndE PF08870.11 CBY24265.1 - 0.15 12.3 1.2 23 5.3 0.1 2.8 2 1 1 3 3 3 0 DNA sulphur modification protein DndE Thioredoxin_7 PF13899.6 CBY24266.1 - 2.1e-14 53.5 0.0 3.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBY24266.1 - 1.3e-06 28.8 0.0 2e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CBY24266.1 - 0.00012 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 CBY24266.1 - 0.00025 21.0 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBY24266.1 - 0.0097 16.2 0.0 0.12 12.7 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 CBY24266.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 PGM_PMM_III PF02880.16 CBY24267.1 - 1.5e-32 112.2 0.0 2.6e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 CBY24267.1 - 5e-29 100.8 0.0 9.7e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CBY24267.1 - 7.9e-15 55.3 0.0 2.1e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CBY24267.1 - 3.8e-06 27.0 0.0 1.1e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF572 PF04502.13 CBY24268.1 - 1.2e-48 166.5 6.4 9.2e-48 163.6 5.4 1.8 1 1 1 2 2 2 2 Family of unknown function (DUF572) Cwf_Cwc_15 PF04889.12 CBY24268.1 - 0.075 12.8 5.0 0.11 12.2 5.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myosin_head PF00063.21 CBY24269.1 - 1.8e-159 532.1 0.0 2.4e-159 531.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) RhoGAP PF00620.27 CBY24269.1 - 1.5e-37 128.7 0.1 4.1e-37 127.3 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain IQ PF00612.27 CBY24269.1 - 2.8e-10 39.0 33.3 0.0002 20.8 0.2 6.6 6 0 0 6 6 6 5 IQ calmodulin-binding motif C1_1 PF00130.22 CBY24269.1 - 1.2e-06 28.2 7.3 2.9e-06 27.1 7.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.23 CBY24269.1 - 7.4e-06 26.5 0.0 3.6e-05 24.3 0.0 2.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FYVE_2 PF02318.16 CBY24269.1 - 0.00041 20.5 3.7 0.0014 18.8 3.7 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger AAA_16 PF13191.6 CBY24269.1 - 0.00097 19.6 0.4 0.027 14.8 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain IIGP PF05049.13 CBY24269.1 - 0.018 14.1 0.9 0.9 8.5 0.1 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 CBY24269.1 - 0.034 14.4 0.1 0.99 9.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain HAD_SAK_2 PF18143.1 CBY24269.1 - 0.041 14.2 4.7 0.16 12.3 0.9 3.2 2 1 0 3 3 3 0 HAD domain in Swiss Army Knife RNA repair proteins zf-RING_9 PF13901.6 CBY24269.1 - 0.068 13.1 9.4 0.039 13.9 4.7 2.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon T2SSE PF00437.20 CBY24269.1 - 0.093 11.8 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein C1_2 PF03107.16 CBY24269.1 - 0.27 11.6 2.4 0.65 10.4 2.4 1.7 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 CBY24269.1 - 0.46 10.1 1.8 1.1 8.9 1.8 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 CBY24269.1 - 0.49 10.5 3.4 1.3 9.2 3.4 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 CBY24269.1 - 0.77 9.7 3.2 1.7 8.6 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 CBY24269.1 - 2 8.4 4.4 5.4 7.0 4.4 1.7 1 0 0 1 1 1 0 PHD-finger ASD2 PF08687.11 CBY24270.1 - 0.11 12.0 13.9 0.031 13.9 10.9 1.5 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Cluap1 PF10234.9 CBY24270.1 - 0.21 11.0 4.5 0.36 10.2 4.5 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 AIP3 PF03915.13 CBY24270.1 - 0.3 10.1 5.8 0.48 9.5 5.8 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 CHDCT2 PF08074.11 CBY24270.1 - 0.84 9.8 2.7 1.6 8.9 2.7 1.5 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain ThrE PF06738.12 CBY24270.1 - 0.88 8.9 8.0 1.4 8.3 8.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter Endomucin PF07010.12 CBY24270.1 - 2.6 8.0 41.8 2.1 8.2 36.7 2.2 2 0 0 2 2 2 0 Endomucin Endostatin PF06482.11 CBY24270.1 - 2.6 7.4 10.0 1.2 8.5 7.7 1.6 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Tmemb_cc2 PF10267.9 CBY24270.1 - 4.3 6.4 14.0 3.9 6.5 13.6 1.3 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TFIIA PF03153.13 CBY24270.1 - 9.8 6.0 13.9 8.4 6.3 12.8 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lectin_C PF00059.21 CBY24272.1 - 5.2e-08 33.6 0.7 1.2e-07 32.4 0.7 1.7 1 0 0 1 1 1 1 Lectin C-type domain Tubulin PF00091.25 CBY24272.1 - 0.058 13.6 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Archease PF01951.16 CBY24274.1 - 2.2e-35 121.9 1.1 4.5e-35 120.9 0.4 1.9 2 0 0 2 2 2 1 Archease protein family (MTH1598/TM1083) Ank_2 PF12796.7 CBY24274.1 - 3e-05 24.5 0.1 0.0021 18.6 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) DUF3782 PF12644.7 CBY24274.1 - 0.032 14.4 0.4 2.4 8.4 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3782) Ank_3 PF13606.6 CBY24274.1 - 0.044 14.3 0.0 0.32 11.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Mad3_BUB1_II PF08171.11 CBY24274.1 - 0.068 13.3 1.4 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 Mob1_phocein PF03637.17 CBY24275.1 - 3.7e-63 212.5 0.2 4.4e-63 212.3 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family Hep_core_N PF08290.11 CBY24275.1 - 0.13 12.2 0.2 0.35 10.9 0.2 1.7 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger NDUF_B5 PF09781.9 CBY24276.1 - 0.0009 18.9 0.1 0.0037 16.9 0.0 1.9 2 0 0 2 2 2 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Aph-1 PF06105.12 CBY24277.1 - 1.1e-36 126.4 13.0 1.3e-36 126.2 13.0 1.0 1 0 0 1 1 1 1 Aph-1 protein PWI PF01480.17 CBY24278.1 - 0.00023 21.4 0.2 0.00046 20.4 0.2 1.5 1 0 0 1 1 1 1 PWI domain MIIP PF15734.5 CBY24279.1 - 1.6e-13 50.8 6.6 4.5e-13 49.4 6.6 1.6 1 1 0 1 1 1 1 Migration and invasion-inhibitory Na_H_Exchanger PF00999.21 CBY24280.1 - 2.6e-67 227.3 37.9 3.3e-67 226.9 37.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3377 PF11857.8 CBY24280.1 - 0.16 11.9 1.8 0.56 10.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) WD40 PF00400.32 CBY24281.1 - 9.5e-19 67.4 14.5 0.0045 17.8 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY24281.1 - 3.2e-12 46.6 4.8 0.01 16.1 0.0 4.7 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY24281.1 - 0.014 14.4 2.0 0.13 11.2 0.1 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VCBS PF13517.6 CBY24281.1 - 0.13 12.9 0.7 25 5.5 0.0 3.9 4 1 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Glycophorin_A PF01102.18 CBY24282.1 - 0.015 15.6 0.1 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 Glycophorin A Calcipressin PF04847.12 CBY24283.1 - 1.4e-28 99.9 0.3 2e-28 99.4 0.3 1.2 1 0 0 1 1 1 1 Calcipressin HAUS6_N PF14661.6 CBY24284.1 - 0.42 10.2 8.6 8.6 5.9 8.6 2.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spc7 PF08317.11 CBY24285.1 - 0.00021 20.3 47.6 0.00053 19.0 18.9 2.8 1 1 2 3 3 3 2 Spc7 kinetochore protein Death PF00531.22 CBY24285.1 - 0.0028 17.8 2.9 0.0046 17.1 0.6 2.5 1 1 1 2 2 2 1 Death domain APG6_N PF17675.1 CBY24285.1 - 0.013 16.0 17.9 0.013 16.0 17.9 3.9 2 2 1 3 3 3 0 Apg6 coiled-coil region MscS_porin PF12795.7 CBY24285.1 - 0.033 13.7 28.9 0.061 12.9 9.4 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF3450 PF11932.8 CBY24285.1 - 0.034 13.5 32.6 0.35 10.2 6.9 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) Vps23_core PF09454.10 CBY24285.1 - 0.037 14.0 1.1 0.5 10.3 0.3 2.9 2 1 0 2 2 2 0 Vps23 core domain Glyco_hydro_59 PF02057.15 CBY24285.1 - 0.17 11.1 2.8 1.3 8.1 0.2 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 DUF3584 PF12128.8 CBY24285.1 - 0.22 9.0 43.8 0.0025 15.4 18.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) DUF725 PF05267.12 CBY24285.1 - 0.28 11.2 13.8 0.16 11.9 5.2 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF725) Fez1 PF06818.15 CBY24285.1 - 1.7 9.1 43.2 3 8.3 15.0 2.8 2 1 0 2 2 2 0 Fez1 CALCOCO1 PF07888.11 CBY24285.1 - 1.8 7.3 45.3 0.015 14.2 34.0 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 CBY24285.1 - 2 8.5 30.1 0.25 11.4 1.8 4.9 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) DUF600 PF04634.12 CBY24285.1 - 4 7.5 11.1 3.4 7.7 0.7 3.5 3 1 0 3 3 3 0 Protein of unknown function, DUF600 OmpH PF03938.14 CBY24285.1 - 5.8 7.2 44.1 0.16 12.3 3.9 4.7 2 2 2 4 4 4 0 Outer membrane protein (OmpH-like) PUL PF08324.11 CBY24286.1 - 5.2e-27 94.8 0.0 7.4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 CBY24286.1 - 2.6e-26 92.1 0.4 1.8e-22 79.7 0.1 2.5 1 1 1 2 2 2 2 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CBY24286.1 - 2.7e-21 75.5 2.1 0.00015 22.4 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat UPF0728 PF15092.6 CBY24287.1 - 1.2e-31 108.4 0.0 1.3e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0728 Ribosomal_L2_C PF03947.18 CBY24289.1 - 8.8e-05 22.7 0.0 0.0043 17.3 0.0 2.5 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBY24289.1 - 0.00019 21.3 0.0 0.00053 19.9 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Zona_pellucida PF00100.23 CBY24290.1 - 4.8e-28 98.7 1.7 6.1e-28 98.3 1.7 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.27 CBY24290.1 - 0.0016 18.7 8.4 0.0016 18.7 8.4 2.3 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 CBY24290.1 - 0.072 13.8 5.2 0.27 11.9 5.2 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF Cyt-b5 PF00173.28 CBY24291.1 - 6.2e-09 35.9 0.0 8.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UBA PF00627.31 CBY24292.1 - 0.045 13.7 0.1 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 UBA/TS-N domain p47_phox_C PF08944.11 CBY24292.1 - 3.7 7.0 9.2 1.1 8.7 1.6 2.5 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain ECH_1 PF00378.20 CBY24293.1 - 4.6e-25 88.4 0.0 4.9e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY24293.1 - 2e-11 44.0 0.0 2.2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1949 PF09186.11 CBY24293.1 - 0.14 12.1 0.2 0.49 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) Arm PF00514.23 CBY24294.1 - 5.4e-66 216.8 11.2 1.2e-11 44.2 0.1 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CBY24294.1 - 7.6e-21 73.4 0.5 2.1e-20 72.0 0.5 1.8 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 CBY24294.1 - 1.9e-18 66.6 2.9 5.7e-18 65.1 2.9 1.9 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 CBY24294.1 - 5.6e-14 52.3 0.1 3e-06 27.5 0.0 5.4 2 1 4 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 CBY24294.1 - 9.2e-11 42.0 5.4 0.0018 18.8 0.2 5.4 4 1 3 7 7 7 3 HEAT-like repeat HEAT PF02985.22 CBY24294.1 - 7.9e-08 31.9 0.2 0.65 10.4 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat DUF3385 PF11865.8 CBY24294.1 - 0.0042 17.0 0.2 0.052 13.5 0.0 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 CBY24294.1 - 0.0056 16.7 0.0 10 6.1 0.0 3.8 2 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 SEN1_N PF12726.7 CBY24294.1 - 0.0066 14.7 0.0 0.11 10.6 0.0 2.5 3 1 1 4 4 4 1 SEN1 N terminal V-ATPase_H_C PF11698.8 CBY24294.1 - 0.083 13.0 1.3 0.57 10.3 0.1 2.9 4 1 2 6 6 6 0 V-ATPase subunit H Phospholip_A2_1 PF00068.19 CBY24295.1 - 4.4e-13 49.7 4.2 4.4e-13 49.7 4.2 3.4 3 0 0 3 3 3 1 Phospholipase A2 HSP20 PF00011.21 CBY24295.1 - 0.00016 21.8 7.6 0.019 15.1 0.5 3.8 4 0 0 4 4 4 2 Hsp20/alpha crystallin family ParcG PF10274.9 CBY24296.1 - 7.3e-83 277.2 0.0 8.3e-83 277.0 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein L51_S25_CI-B8 PF05047.16 CBY24297.1 - 1.7e-05 24.6 0.1 4.3e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RNA_polI_A34 PF08208.11 CBY24298.1 - 0.5 10.4 11.6 0.45 10.6 0.1 2.2 1 1 1 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Proteasome PF00227.26 CBY24299.1 - 1e-51 175.1 0.0 1.3e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBY24299.1 - 5e-14 51.7 0.0 9.8e-14 50.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AAA_19 PF13245.6 CBY24300.1 - 4.9e-07 30.2 0.0 0.0015 18.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain DEAD PF00270.29 CBY24300.1 - 0.00029 20.6 0.1 0.00079 19.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 CBY24300.1 - 0.004 16.7 0.1 0.22 11.0 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CBY24300.1 - 0.026 14.5 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CBY24300.1 - 0.033 13.8 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY24300.1 - 0.068 12.9 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain KdpD PF02702.17 CBY24300.1 - 0.095 12.2 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain MRG PF05712.13 CBY24302.1 - 1.8e-27 96.0 1.1 1.1e-26 93.4 1.1 1.9 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 CBY24302.1 - 2.6e-07 30.4 0.2 5.8e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pox_MCEL PF03291.16 CBY24302.1 - 0.056 12.5 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme MRG PF05712.13 CBY24303.1 - 4.2e-20 71.9 1.0 4.8e-20 71.7 1.0 1.0 1 0 0 1 1 1 1 MRG Glyco_hydro_cc PF11790.8 CBY24303.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core ubiquitin PF00240.23 CBY24304.1 - 2.5e-20 72.0 0.1 2.9e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY24304.1 - 7.1e-10 38.6 0.1 7.8e-10 38.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBY24304.1 - 0.00036 20.9 0.1 0.0013 19.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBY24304.1 - 0.00061 19.7 0.0 0.00068 19.5 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBY24304.1 - 0.0068 16.5 0.0 0.0089 16.1 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CBY24304.1 - 0.016 15.5 0.1 0.017 15.5 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain UN_NPL4 PF11543.8 CBY24304.1 - 0.058 13.9 0.1 0.094 13.2 0.1 1.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF2407 PF10302.9 CBY24304.1 - 0.13 12.8 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DNA_pol_A PF00476.20 CBY24305.1 - 2.3e-76 257.3 0.1 6e-76 255.9 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase family A DEAD PF00270.29 CBY24305.1 - 3.2e-15 56.4 0.0 2.7e-14 53.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY24305.1 - 1.3e-11 44.8 0.2 1.1e-09 38.6 0.1 3.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY24305.1 - 5.4e-10 39.5 0.3 2.7e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 CBY24305.1 - 0.0069 16.3 0.0 0.03 14.2 0.0 2.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea YjeF_N PF03853.15 CBY24306.1 - 5.9e-15 55.6 0.0 7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pkinase PF00069.25 CBY24307.1 - 1e-13 51.3 0.0 2e-13 50.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24307.1 - 8.1e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY24307.1 - 0.079 11.9 5.6 0.14 11.1 0.1 2.1 2 0 0 2 2 2 0 Haspin like kinase domain TTL PF03133.15 CBY24309.1 - 3.4e-84 282.5 0.1 3.4e-84 282.5 0.1 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY24309.1 - 3.4e-07 29.8 2.6 0.00018 20.8 0.0 3.6 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY24309.1 - 2.5e-05 23.7 0.1 0.0049 16.2 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 CBY24309.1 - 0.0036 16.9 0.2 0.38 10.3 0.1 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 CBY24309.1 - 0.0053 16.3 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CBY24309.1 - 0.01 15.9 0.0 4.6 7.3 0.0 2.7 2 0 0 2 2 2 0 ATP-grasp domain Pkinase PF00069.25 CBY24310.1 - 1.4e-64 218.0 0.0 1.8e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24310.1 - 1.8e-47 161.8 0.0 2.1e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY24310.1 - 4.6e-05 22.5 0.3 0.00013 21.1 0.3 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY24310.1 - 0.00038 19.4 0.0 0.00053 18.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY24310.1 - 0.0019 17.5 0.1 0.0056 16.0 0.1 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY24310.1 - 0.0028 17.1 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBY24310.1 - 0.019 14.6 0.2 0.31 10.6 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBY24310.1 - 0.052 13.5 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family RuvC_1 PF18516.1 CBY24310.1 - 0.11 11.7 0.2 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 RuvC nuclease domain UCH PF00443.29 CBY24311.1 - 6.9e-17 61.8 1.8 6.9e-17 61.8 1.8 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Laminin_II PF06009.12 CBY24313.1 - 0.00044 20.3 12.2 0.00044 20.3 12.2 4.9 2 1 2 4 4 4 2 Laminin Domain II Aldedh PF00171.22 CBY24315.1 - 4.6e-15 55.1 0.0 5e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sugarporin_N PF11471.8 CBY24317.1 - 0.039 13.9 0.2 3.4 7.7 0.1 3.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension NAD_binding_2 PF03446.15 CBY24317.1 - 1.1 9.4 3.9 9.6 6.4 3.9 2.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF5125 PF17163.4 CBY24319.1 - 0.0075 16.5 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5125) zf-C2H2_jaz PF12171.8 CBY24320.1 - 0.025 14.9 0.5 0.069 13.5 0.5 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY24320.1 - 0.048 14.1 2.2 0.053 13.9 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type 2OG-FeII_Oxy_3 PF13640.6 CBY24321.1 - 0.00095 20.0 0.0 0.0024 18.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1235 PF06822.12 CBY24321.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) zf-H2C2_2 PF13465.6 CBY24322.1 - 7.5e-23 79.9 27.9 8.6e-08 32.3 2.9 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY24322.1 - 4.9e-21 74.0 26.5 1.6e-06 28.2 3.5 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY24322.1 - 2.8e-18 65.0 25.0 0.00023 21.7 2.2 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY24322.1 - 9.3e-11 41.7 13.5 0.0021 18.3 0.1 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY24322.1 - 1.6e-09 37.6 20.6 0.00058 19.8 2.0 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 CBY24322.1 - 1.5e-08 34.8 13.4 1e-06 28.9 3.9 3.1 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY24322.1 - 3.5e-07 30.4 19.5 0.001 19.4 0.8 4.3 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-BED PF02892.15 CBY24322.1 - 9.6e-07 28.7 15.6 0.0016 18.5 3.2 3.4 2 1 1 3 3 3 2 BED zinc finger GAGA PF09237.11 CBY24322.1 - 2.4e-05 24.0 8.5 0.34 10.7 0.1 4.0 1 1 3 4 4 4 2 GAGA factor zinc_ribbon_15 PF17032.5 CBY24322.1 - 6.5e-05 23.6 5.5 0.071 13.9 0.2 2.1 1 1 1 2 2 2 2 zinc-ribbon family Prok-RING_1 PF14446.6 CBY24322.1 - 0.0004 20.2 8.2 1.5 8.8 0.1 4.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 Zn-C2H2_12 PF18112.1 CBY24322.1 - 0.00045 20.6 10.5 1.3 9.5 0.5 4.4 4 0 0 4 4 4 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 CBY24322.1 - 0.00072 19.9 16.8 0.28 11.5 0.9 4.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 CBY24322.1 - 0.0016 18.5 13.0 1.2 9.3 1.7 4.0 1 1 3 4 4 4 2 KIAA1045 RING finger Zn-ribbon_8 PF09723.10 CBY24322.1 - 0.0042 17.2 11.9 0.014 15.5 1.7 3.5 2 1 2 4 4 4 1 Zinc ribbon domain BolA PF01722.18 CBY24322.1 - 0.0071 16.6 5.6 4.7 7.6 0.5 3.2 2 1 1 3 3 3 0 BolA-like protein HypA PF01155.19 CBY24322.1 - 0.017 15.1 6.2 0.71 9.9 2.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_9 PF16293.5 CBY24322.1 - 0.02 14.8 7.9 2.8 7.9 0.1 3.5 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-CHCC PF10276.9 CBY24322.1 - 0.022 14.8 6.1 1.8 8.7 0.1 3.4 4 0 0 4 4 4 0 Zinc-finger domain zf-C2H2_3rep PF18868.1 CBY24322.1 - 0.023 15.4 11.8 0.81 10.4 1.9 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Cys_rich_CPXG PF14255.6 CBY24322.1 - 0.034 14.1 5.0 1.2 9.1 0.6 3.4 3 1 0 3 3 3 0 Cysteine-rich CPXCG FYVE PF01363.21 CBY24322.1 - 0.072 13.2 15.7 0.59 10.3 10.6 2.9 1 1 1 2 2 2 0 FYVE zinc finger zf-H2C2_5 PF13909.6 CBY24322.1 - 0.076 12.8 26.4 0.32 10.8 1.7 5.2 4 2 0 4 4 4 0 C2H2-type zinc-finger domain MCM_OB PF17207.3 CBY24322.1 - 0.095 12.5 7.0 0.095 12.6 0.6 2.1 1 1 1 2 2 2 0 MCM OB domain zf-AN1 PF01428.16 CBY24322.1 - 0.18 12.0 17.3 1.4 9.2 0.9 4.2 3 1 1 4 4 4 0 AN1-like Zinc finger zf-MYST PF17772.1 CBY24322.1 - 0.39 10.3 12.0 2.4 7.8 0.4 3.9 4 0 0 4 4 4 0 MYST family zinc finger domain HNH_5 PF14279.6 CBY24322.1 - 0.67 9.9 8.9 7.2 6.6 0.4 3.8 3 1 0 3 3 3 0 HNH endonuclease C1_4 PF07975.12 CBY24322.1 - 0.9 9.8 14.6 2.8 8.2 0.6 3.2 1 1 3 4 4 4 0 TFIIH C1-like domain YHS PF04945.13 CBY24322.1 - 1.2 9.3 0.1 1.2 9.3 0.1 2.8 3 0 0 3 3 3 0 YHS domain zf-C3HC4 PF00097.25 CBY24322.1 - 1.3 8.9 7.1 5.3e+02 0.6 0.1 3.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYDLN_acid PF09538.10 CBY24322.1 - 1.4 9.6 5.2 8 7.2 0.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-met2 PF12907.7 CBY24322.1 - 1.7 8.9 11.1 8.7 6.6 0.9 3.6 3 0 0 3 3 3 0 Zinc-binding LIM PF00412.22 CBY24322.1 - 1.7 9.0 13.6 16 5.8 2.2 3.6 1 1 3 4 4 4 0 LIM domain DUF2256 PF10013.9 CBY24322.1 - 2.7 8.2 11.1 20 5.4 0.2 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) XPA_N PF01286.18 CBY24322.1 - 4 7.6 13.8 8.7 6.5 0.1 4.0 4 0 0 4 4 4 0 XPA protein N-terminal zf_ZIC PF18366.1 CBY24322.1 - 4.5 7.5 14.0 0.28 11.3 0.7 3.5 2 1 2 4 4 4 0 Zic proteins zinc finger domain zf_UBZ PF18439.1 CBY24322.1 - 5.8 6.6 11.4 3.3 7.4 0.3 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 CBY24322.1 - 6 6.7 0.0 6 6.7 0.0 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type UBZ_FAAP20 PF15750.5 CBY24322.1 - 7.5 6.6 12.8 7.3 6.6 0.7 3.9 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger VWA PF00092.28 CBY24323.1 - 0.1 12.8 0.1 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA PF00092.28 CBY24326.1 - 0.041 14.1 0.2 0.29 11.4 0.0 2.2 2 1 0 2 2 2 0 von Willebrand factor type A domain PH PF00169.29 CBY24327.1 - 3.5e-07 30.7 0.1 7.2e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 PH domain RA PF00788.23 CBY24327.1 - 4.2e-07 30.5 0.1 8.8e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain fn3 PF00041.21 CBY24328.1 - 2.5e-77 255.3 2.8 3.3e-15 56.2 0.0 8.7 7 1 1 8 8 8 8 Fibronectin type III domain I-set PF07679.16 CBY24328.1 - 6.4e-16 58.2 0.3 5e-06 26.5 0.3 4.3 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY24328.1 - 2.1e-14 53.9 0.4 3.9e-05 24.2 0.2 3.9 3 0 0 3 3 3 3 Immunoglobulin domain fn3 PF00041.21 CBY24329.1 - 0 1237.6 31.5 3.3e-14 53.0 0.2 31.8 31 0 0 31 31 31 30 Fibronectin type III domain I-set PF07679.16 CBY24329.1 - 5.3e-196 635.4 25.9 1.9e-15 56.7 0.0 20.1 22 0 0 22 22 20 16 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY24329.1 - 1.4e-128 419.7 4.3 6.2e-09 36.3 0.0 18.6 18 0 0 18 18 18 16 Immunoglobulin domain ig PF00047.25 CBY24329.1 - 7.2e-67 221.6 5.7 8.3e-05 22.7 0.1 15.4 15 0 0 15 15 15 12 Immunoglobulin domain Ig_2 PF13895.6 CBY24329.1 - 1.8e-46 156.3 2.6 0.00096 19.4 0.0 16.1 16 0 0 16 16 15 9 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY24329.1 - 2.9e-41 139.9 31.0 0.044 14.4 0.1 25.6 25 2 0 25 25 25 8 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 CBY24329.1 - 4.4e-20 71.9 2.7 2 8.6 0.0 14.5 15 0 0 15 15 15 4 Immunoglobulin V-set domain fn3_2 PF16893.5 CBY24329.1 - 3e-17 62.5 0.0 0.046 13.9 0.0 11.9 13 0 0 13 13 11 3 Fibronectin type III domain Tissue_fac PF01108.17 CBY24329.1 - 3.6e-15 55.7 17.2 0.07 13.0 0.0 14.1 13 0 0 13 13 13 3 Tissue factor Receptor_2B4 PF11465.8 CBY24329.1 - 4.2e-12 46.2 14.0 5.9 7.1 0.0 14.0 14 2 2 16 16 16 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 CBY24329.1 - 3.3e-11 43.1 11.7 3 8.0 0.0 10.8 13 0 0 13 13 12 2 CD80-like C2-set immunoglobulin domain PhoD_N PF16655.5 CBY24329.1 - 3.1e-08 34.0 2.6 4 8.0 0.0 10.8 14 0 0 14 14 11 1 PhoD-like phosphatase, N-terminal domain Adeno_E3_CR1 PF02440.15 CBY24329.1 - 7.4e-07 28.9 0.0 0.19 11.5 0.0 6.2 5 0 0 5 5 5 1 Adenovirus E3 region protein CR1 Herpes_gE PF02480.16 CBY24329.1 - 4e-06 25.8 1.7 0.21 10.3 0.0 5.5 6 0 0 6 6 6 2 Alphaherpesvirus glycoprotein E Ig_6 PF18452.1 CBY24329.1 - 9.8e-06 25.0 0.4 0.24 11.0 0.1 5.6 5 0 0 5 5 5 1 Immunoglobulin domain DUF2369 PF10179.9 CBY24329.1 - 2.4e-05 24.6 4.6 1.2e+02 3.1 0.0 11.1 14 0 0 14 14 13 0 Uncharacterised conserved protein (DUF2369) Big_3 PF07523.12 CBY24329.1 - 0.12 12.7 1.2 5.3 7.4 0.1 3.6 3 0 0 3 3 2 0 Bacterial Ig-like domain (group 3) PA_decarbox PF05870.11 CBY24329.1 - 0.12 11.9 0.6 6.9 6.3 0.0 4.0 4 0 0 4 4 4 0 Phenolic acid decarboxylase (PAD) RRM_1 PF00076.22 CBY24330.1 - 2.2e-24 85.0 0.1 7.8e-15 54.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY24330.1 - 3.3e-06 27.1 0.1 0.14 12.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif DND1_DSRM PF14709.7 CBY24331.1 - 5.3e-20 71.5 1.2 5.9e-20 71.3 0.1 1.7 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 CBY24331.1 - 0.21 12.3 0.0 0.21 12.3 0.0 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif WD40_3 PF15911.5 CBY24332.1 - 2.7e-09 36.9 0.0 9.5e-09 35.1 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY24332.1 - 1.1e-06 28.8 1.0 0.45 10.8 0.1 5.7 3 2 3 6 6 5 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 CBY24332.1 - 1.2e-06 28.5 1.7 1.5 8.7 0.1 5.0 4 0 0 4 4 4 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 CBY24332.1 - 5.7e-06 25.6 8.1 0.032 13.3 0.3 5.6 5 1 2 7 7 7 2 Coatomer WD associated region TPR_14 PF13428.6 CBY24332.1 - 0.00019 22.0 3.9 1.1 10.2 0.1 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY24332.1 - 0.00089 19.7 6.5 3.1 8.4 0.2 5.9 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY24332.1 - 0.0012 18.8 18.6 9.4 6.6 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY24332.1 - 0.0014 18.8 6.4 4.1 7.7 0.0 5.8 6 1 1 7 7 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Rad50_zn_hook PF04423.14 CBY24332.1 - 0.016 15.0 0.5 0.016 15.0 0.5 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif TPR_7 PF13176.6 CBY24332.1 - 0.32 11.1 11.9 45 4.4 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY24332.1 - 0.32 10.7 5.7 19 5.0 0.1 4.5 4 0 0 4 4 4 0 TPR repeat WD40 PF00400.32 CBY24332.1 - 0.34 11.9 6.8 1.7e+02 3.3 0.1 6.1 5 1 1 6 6 6 0 WD domain, G-beta repeat TPR_8 PF13181.6 CBY24332.1 - 0.35 11.2 11.4 2.5 8.5 0.1 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY24332.1 - 0.56 10.5 8.5 42 4.5 0.3 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY24332.1 - 0.78 9.7 13.5 21 5.2 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 CBY24332.1 - 6.6 6.3 6.0 6.2 6.4 1.8 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CBY24332.1 - 7.5 6.7 11.5 3.9 7.6 1.3 2.5 1 1 1 2 2 2 0 Double zinc ribbon CHD5 PF04420.14 CBY24333.1 - 2.7e-10 40.3 1.4 4.8e-10 39.5 1.4 1.5 1 1 0 1 1 1 1 CHD5-like protein dNK PF01712.19 CBY24334.1 - 2.9e-62 210.2 0.0 3.4e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 CBY24334.1 - 1.9e-05 25.2 1.6 0.00034 21.2 0.1 3.0 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 CBY24334.1 - 0.0029 17.3 1.4 0.023 14.4 0.1 2.6 1 1 1 2 2 2 1 Thymidylate kinase AAA_33 PF13671.6 CBY24334.1 - 0.03 14.5 0.1 1.1 9.4 0.1 2.5 1 1 0 1 1 1 0 AAA domain Spore_IV_A PF09547.10 CBY24334.1 - 0.061 12.2 0.4 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) Gp58 PF07902.11 CBY24334.1 - 0.16 10.2 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein AAA_28 PF13521.6 CBY24334.1 - 0.29 11.4 1.3 0.91 9.7 0.4 2.3 1 1 1 2 2 2 0 AAA domain ASH PF15780.5 CBY24335.1 - 0.00034 20.8 6.8 0.0021 18.2 0.1 4.1 3 1 2 5 5 5 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 CBY24335.1 - 0.002 18.1 0.9 1 9.4 0.1 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF1573) ASH PF15780.5 CBY24336.1 - 2.1e-44 149.7 28.6 0.015 15.4 0.0 24.2 23 3 2 25 25 25 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Hydin_ADK PF17213.3 CBY24336.1 - 3.4e-19 69.9 1.1 3.4e-19 69.9 1.1 3.8 2 2 0 2 2 1 1 Hydin Adenylate kinase-like domain Motile_Sperm PF00635.26 CBY24336.1 - 2.1e-18 66.1 34.3 0.0082 16.0 0.1 18.5 25 0 0 25 25 23 5 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBY24336.1 - 1.3e-17 63.6 20.2 0.14 12.2 0.0 17.2 20 0 0 20 20 20 3 Protein of unknown function (DUF1573) PapD-like PF14874.6 CBY24336.1 - 3.6e-13 49.5 0.3 2.7 8.2 0.0 12.1 14 0 0 14 14 14 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 CBY24336.1 - 2e-08 34.3 16.7 1.9 8.8 0.6 12.1 14 0 0 14 14 13 1 Transmembrane protein 131-like FixG_C PF11614.8 CBY24336.1 - 0.00036 20.8 6.6 16 5.7 0.1 8.1 8 0 0 8 8 8 1 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF5001 PF16392.5 CBY24336.1 - 0.0048 16.8 16.3 6.6 6.7 0.0 10.1 10 1 0 10 10 10 1 Ig-like domain SKI PF01202.22 CBY24336.1 - 0.03 14.4 4.5 0.18 11.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_17 PF13207.6 CBY24336.1 - 0.068 13.6 0.0 0.068 13.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Transglut_C PF00927.22 CBY24336.1 - 0.17 12.1 0.8 1.7e+02 2.4 0.0 6.3 7 0 0 7 7 7 0 Transglutaminase family, C-terminal ig like domain DnaJ_C PF01556.18 CBY24337.1 - 1.1e-37 129.4 0.1 1.5e-37 129.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBY24337.1 - 7e-21 74.1 0.6 1.1e-20 73.5 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 CBY24338.1 - 3.1e-20 72.6 0.0 6.2e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24338.1 - 1e-12 47.9 0.0 2.5e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.32 CBY24338.1 - 1.2e-10 41.8 7.8 0.055 14.4 0.2 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat HEAT PF02985.22 CBY24338.1 - 0.0019 18.3 0.1 7.9 7.0 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat Kinase-like PF14531.6 CBY24338.1 - 0.006 15.9 0.0 0.023 14.0 0.0 2.0 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.7 CBY24338.1 - 0.088 12.8 3.9 0.42 10.6 0.1 3.0 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 PQQ_3 PF13570.6 CBY24338.1 - 0.09 13.3 0.2 5.3 7.7 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain HalOD1 PF18545.1 CBY24338.1 - 0.1 12.9 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Halobacterial output domain 1 Methyltransf_16 PF10294.9 CBY24339.1 - 6.4e-33 113.9 0.0 8.9e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CBY24339.1 - 0.00022 21.1 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY24339.1 - 0.015 15.1 0.1 0.15 11.9 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CBY24339.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ELYS PF13934.6 CBY24340.1 - 2.2e-14 54.0 0.1 3.9e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly LEM PF03020.15 CBY24340.1 - 0.13 11.9 0.2 0.43 10.2 0.2 1.9 1 0 0 1 1 1 0 LEM domain TIP41 PF04176.13 CBY24341.1 - 6.7e-54 181.9 1.9 8.5e-54 181.6 1.9 1.1 1 0 0 1 1 1 1 TIP41-like family OLF PF02191.16 CBY24342.1 - 9.3e-75 251.4 9.7 1.8e-74 250.4 9.7 1.5 1 0 0 1 1 1 1 Olfactomedin-like domain SNF2_N PF00176.23 CBY24342.1 - 8.2e-57 192.5 0.0 1.6e-56 191.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY24342.1 - 8.2e-15 55.1 0.0 5.7e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY24342.1 - 1.3e-08 35.0 0.0 4.9e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rad54_N PF08658.10 CBY24342.1 - 5.2e-06 26.7 1.1 9.9e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 Rad54 N terminal HDA2-3 PF11496.8 CBY24342.1 - 6e-05 22.4 0.0 0.00033 19.9 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.25 CBY24343.1 - 2.3e-67 227.2 0.0 3.5e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24343.1 - 4.3e-50 170.4 0.0 6.7e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 CBY24343.1 - 1.1e-11 44.2 2.9 0.00025 20.8 0.0 4.3 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CBY24343.1 - 7.7e-07 29.6 1.2 6 7.6 0.0 5.6 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Haspin_kinase PF12330.8 CBY24343.1 - 0.00025 20.1 1.0 0.00044 19.3 1.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBY24343.1 - 0.0043 16.4 0.2 0.0076 15.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY24343.1 - 0.0076 15.1 0.2 0.075 11.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBY24343.1 - 0.021 14.8 0.6 0.62 9.9 0.5 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Cnd3 PF12719.7 CBY24344.1 - 8.2e-12 44.9 4.8 1.4e-11 44.2 2.8 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CBY24344.1 - 0.0054 17.1 12.2 0.81 10.1 0.5 5.2 3 2 1 5 5 5 2 HEAT repeats Cohesin_HEAT PF12765.7 CBY24344.1 - 0.014 15.7 3.6 2 8.8 0.3 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 CBY24344.1 - 0.016 15.4 13.2 0.96 9.9 0.1 6.4 7 0 0 7 7 7 0 HEAT repeat DUF5388 PF17363.2 CBY24344.1 - 0.02 15.0 0.6 5.1 7.4 0.0 4.1 3 0 0 3 3 3 0 Family of unknown function (DUF5388) Y_phosphatase PF00102.27 CBY24345.1 - 5.6e-64 215.9 1.6 2.2e-63 214.0 1.7 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase SH2 PF00017.24 CBY24345.1 - 9.2e-34 115.4 0.2 2.9e-15 56.1 0.0 3.3 3 1 0 3 3 3 2 SH2 domain SH2_2 PF14633.6 CBY24345.1 - 7.4e-07 28.8 0.0 0.0053 16.2 0.0 2.2 2 0 0 2 2 2 2 SH2 domain PTPlike_phytase PF14566.6 CBY24345.1 - 0.00025 21.2 0.0 0.0007 19.7 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 CBY24345.1 - 0.00058 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBY24345.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family BicD PF09730.9 CBY24346.1 - 2.9e-95 320.2 82.8 4e-67 227.2 19.4 3.8 1 1 3 4 4 4 3 Microtubule-associated protein Bicaudal-D Mce4_CUP1 PF11887.8 CBY24346.1 - 0.11 12.0 1.8 0.31 10.4 1.8 1.8 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative ZnuA PF01297.17 CBY24346.1 - 4.5 6.6 16.4 0.025 14.0 1.5 3.0 3 0 0 3 3 3 0 Zinc-uptake complex component A periplasmic GST_N_3 PF13417.6 CBY24347.1 - 3.2e-10 40.3 0.0 5.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBY24347.1 - 1.1e-07 32.0 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY24347.1 - 6.3e-07 29.6 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY24347.1 - 6.5e-07 29.6 0.0 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY24347.1 - 0.0014 18.8 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY24347.1 - 0.038 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Lectin_C PF00059.21 CBY24348.1 - 1.1e-46 158.0 26.8 6.7e-14 52.5 4.2 5.6 6 0 0 6 6 6 5 Lectin C-type domain EMP24_GP25L PF01105.24 CBY24348.1 - 3.1e-43 147.8 0.0 4.6e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Nudix_hydro PF18290.1 CBY24348.1 - 0.13 12.3 0.6 0.74 9.8 0.0 2.5 3 0 0 3 3 3 0 Nudix hydrolase domain UL45 PF05473.12 CBY24348.1 - 1.1 8.8 7.1 0.5 10.0 0.0 3.8 4 1 0 4 4 4 0 UL45 protein, carbohydrate-binding C-type lectin-like TEA PF01285.18 CBY24349.1 - 2.2e-27 94.9 0.0 8.9e-27 93.0 0.0 2.0 2 0 0 2 2 2 1 TEA/ATTS domain YBD PF17725.1 CBY24349.1 - 5.4e-25 88.5 0.1 7.4e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 YAP binding domain Sulfotransfer_2 PF03567.14 CBY24350.1 - 1.1e-07 32.1 1.7 4.1e-07 30.2 0.9 2.1 2 0 0 2 2 2 1 Sulfotransferase family Pkinase PF00069.25 CBY24351.1 - 1e-20 74.2 0.6 5e-16 58.9 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24351.1 - 7.5e-16 58.2 0.2 3.6e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY24351.1 - 0.0043 15.9 0.0 0.0073 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBY24351.1 - 0.27 10.7 0.0 0.27 10.7 0.0 2.4 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Sushi PF00084.20 CBY24352.1 - 6.5e-06 26.7 15.8 0.0056 17.3 6.1 2.6 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Selenoprotein_S PF06936.11 CBY24352.1 - 1.3 8.7 9.6 3.4 7.4 9.6 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF3824 PF12868.7 CBY24352.1 - 3.4 8.3 9.4 0.67 10.6 4.5 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Amino_oxidase PF01593.24 CBY24354.1 - 6e-11 42.3 0.0 9.2e-10 38.4 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CBY24354.1 - 6.7e-08 32.6 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CBY24354.1 - 0.00022 21.0 0.0 0.00033 20.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CBY24354.1 - 0.017 14.4 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 CBY24354.1 - 0.033 13.4 0.0 0.075 12.3 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 CBY24354.1 - 0.045 13.0 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CBY24354.1 - 0.1 11.8 0.1 4.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PhoPQ_related PF10142.9 CBY24355.1 - 8.6e-71 238.5 0.0 1.2e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Trefoil PF00088.18 CBY24356.1 - 0.012 15.5 4.5 0.021 14.7 4.5 1.5 1 0 0 1 1 1 0 Trefoil (P-type) domain Trypsin PF00089.26 CBY24357.1 - 1.2e-51 175.7 1.3 1.4e-51 175.5 1.3 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY24357.1 - 0.0008 19.8 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY24357.1 - 0.002 19.1 0.0 0.0041 18.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain p450 PF00067.22 CBY24358.1 - 7.8e-46 156.8 0.0 6.6e-43 147.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Galactosyl_T PF01762.21 CBY24359.1 - 8.4e-35 120.4 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Chitin_bind_1 PF00187.19 CBY24359.1 - 6.9 7.2 10.4 6.7 7.3 5.7 2.5 2 0 0 2 2 2 0 Chitin recognition protein Na_H_Exchanger PF00999.21 CBY24360.1 - 5.2e-52 176.9 21.5 6.2e-52 176.7 21.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 CBY24360.1 - 0.071 13.4 8.6 0.15 12.3 8.6 1.5 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Pkinase PF00069.25 CBY24362.1 - 1.1e-58 198.7 0.0 1.2e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24362.1 - 4.5e-21 75.3 0.0 6e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY24362.1 - 6.5e-08 32.2 0.0 9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY24362.1 - 1.6e-06 27.6 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY24362.1 - 0.036 13.7 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CBY24362.1 - 0.055 13.4 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBY24362.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF1129 PF06570.11 CBY24363.1 - 1.8 8.0 6.2 2.4 7.6 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Aa_trans PF01490.18 CBY24364.1 - 8.8e-74 248.6 34.1 5e-40 137.5 12.8 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Lipocalin PF00061.23 CBY24365.1 - 0.004 17.4 0.0 0.0051 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DHR-2 PF06920.13 CBY24366.1 - 6.9e-60 203.2 0.7 6.9e-60 203.2 0.7 2.2 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 CBY24366.1 - 2.4e-40 138.5 0.1 4.8e-40 137.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ank_2 PF12796.7 CBY24367.1 - 6.8e-57 190.0 2.2 2.3e-12 47.3 0.2 6.1 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) KAP_NTPase PF07693.14 CBY24367.1 - 1e-47 163.0 0.0 1.6e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Ank_5 PF13857.6 CBY24367.1 - 5e-46 154.2 5.1 1.9e-11 44.0 0.0 9.3 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY24367.1 - 6.3e-41 138.2 3.6 5.7e-09 36.3 0.0 9.4 2 2 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24367.1 - 1.8e-36 120.0 1.5 0.0028 18.0 0.0 11.5 11 0 0 11 11 11 8 Ankyrin repeat Ank PF00023.30 CBY24367.1 - 3e-34 116.0 2.5 0.00082 19.7 0.1 11.0 11 0 0 11 11 11 9 Ankyrin repeat Ets PF00178.22 CBY24368.1 - 5.1e-35 119.8 2.4 8.9e-35 119.0 2.4 1.4 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.17 CBY24368.1 - 0.096 13.3 0.5 0.17 12.5 0.2 1.6 2 0 0 2 2 2 0 HSF-type DNA-binding Neur_chan_LBD PF02931.23 CBY24369.1 - 7.2e-35 120.4 5.0 7.9e-35 120.3 5.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain CTP_synth_N PF06418.14 CBY24371.1 - 4.2e-122 406.6 0.4 5.9e-122 406.1 0.4 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CBY24371.1 - 8.2e-54 182.3 0.0 1.2e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CBY24371.1 - 2.2e-07 30.9 0.1 5.9e-07 29.5 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 CBY24371.1 - 0.0055 16.7 0.0 0.044 13.8 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Rad60-SLD PF11976.8 CBY24372.1 - 5e-22 77.5 0.2 6e-22 77.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY24372.1 - 4.7e-10 39.1 0.1 5.9e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY24373.1 - 1.4e-05 24.8 0.3 0.00065 19.5 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Utp12 PF04003.12 CBY24374.1 - 1.4e-10 41.5 0.0 2.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 CBY24374.1 - 0.046 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain ANAPC4_WD40 PF12894.7 CBY24374.1 - 0.12 12.7 0.0 0.43 10.9 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4123 PF13503.6 CBY24374.1 - 0.31 11.5 1.4 8.3 6.8 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4123) DAO PF01266.24 CBY24375.1 - 1.2e-08 34.9 0.0 2.3e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 CBY24376.1 - 2.5e-38 132.6 0.0 2.9e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CBY24376.1 - 0.00069 18.9 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 CBY24376.1 - 0.0023 18.1 0.1 0.0072 16.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 CBY24376.1 - 0.022 13.3 0.0 0.08 11.5 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 CBY24376.1 - 0.067 12.3 0.1 0.098 11.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 CBY24376.1 - 0.075 12.3 0.8 4.6 6.4 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CBY24376.1 - 0.084 12.1 0.3 0.43 9.8 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBY24376.1 - 0.15 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3502 PF12010.8 CBY24377.1 - 0.042 14.5 0.8 0.07 13.8 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) Peptidase_C78 PF07910.13 CBY24378.1 - 4.5e-37 127.6 0.1 5.6e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CBY24378.1 - 0.0027 17.2 4.2 2.8 7.3 1.1 3.0 1 1 2 3 3 3 3 Peptidase family C54 AAA_12 PF13087.6 CBY24378.1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Leo1 PF04004.13 CBY24379.1 - 4.9e-47 159.8 1.3 7.3e-47 159.3 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein Meckelin PF09773.9 CBY24380.1 - 7.7e-235 781.8 12.1 7.7e-235 781.8 12.1 2.0 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) Abhydrolase_9_N PF15420.6 CBY24380.1 - 0.39 10.7 2.0 0.73 9.8 0.2 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus I-set PF07679.16 CBY24381.1 - 2.7e-110 360.7 0.0 5.3e-17 61.7 0.0 11.6 11 0 0 11 11 11 10 Immunoglobulin I-set domain Glyco_hydro_47 PF01532.20 CBY24381.1 - 7.2e-108 361.4 0.0 1.7e-107 360.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ig_3 PF13927.6 CBY24381.1 - 1.9e-81 268.7 0.0 2.1e-12 47.4 0.0 11.8 11 0 0 11 11 11 9 Immunoglobulin domain ig PF00047.25 CBY24381.1 - 4.9e-32 110.0 19.4 4.5e-07 29.9 0.1 10.7 13 0 0 13 13 11 6 Immunoglobulin domain Ig_2 PF13895.6 CBY24381.1 - 1.7e-30 105.2 2.7 4.3e-06 27.0 0.0 8.3 8 0 0 8 8 8 4 Immunoglobulin domain V-set PF07686.17 CBY24381.1 - 7.9e-15 55.0 6.2 0.19 11.9 0.0 9.6 8 1 2 10 10 10 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY24381.1 - 2.3e-08 34.0 10.0 0.31 11.1 0.0 7.5 7 0 0 7 7 7 2 CD80-like C2-set immunoglobulin domain PA PF02225.22 CBY24381.1 - 5.7e-08 32.7 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 PA domain BiPBP_C PF06832.12 CBY24381.1 - 5.9e-07 29.4 0.0 0.12 12.5 0.0 6.9 7 0 0 7 7 7 1 Penicillin-Binding Protein C-terminus Family Izumo-Ig PF16706.5 CBY24381.1 - 3e-05 24.0 0.7 1.2 9.2 0.0 6.2 8 0 0 8 8 7 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 CBY24381.1 - 0.078 13.3 5.1 24 5.3 0.0 5.6 6 0 0 6 6 5 0 T-cell surface glycoprotein CD3 delta chain PAS_5 PF07310.13 CBY24381.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF4198 PF10670.9 CBY24381.1 - 0.13 12.6 0.1 14 5.9 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4198) Peptidase_M13 PF01431.21 CBY24381.1 - 0.39 10.3 4.4 6.4 6.3 0.9 2.6 2 0 0 2 2 2 0 Peptidase family M13 RRM_1 PF00076.22 CBY24382.1 - 3.4e-17 62.0 0.0 4.6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY24382.1 - 6.1e-06 25.8 0.0 7.4e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CBY24382.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain CCDC71L PF15374.6 CBY24382.1 - 0.047 13.0 4.4 0.054 12.8 4.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L PRE_C2HC PF07530.11 CBY24382.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Associated with zinc fingers CDC45 PF02724.14 CBY24382.1 - 4.3 5.5 5.8 4.1 5.6 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Ssu72 PF04722.13 CBY24383.1 - 7.1e-78 260.6 1.3 8e-78 260.4 1.3 1.0 1 0 0 1 1 1 1 Ssu72-like protein RRM_1 PF00076.22 CBY24385.1 - 2.6e-15 56.0 0.0 4.3e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Swi5 PF07061.11 CBY24386.1 - 0.0049 16.9 4.6 0.0049 16.9 4.6 3.4 3 1 1 4 4 4 1 Swi5 DUF724 PF05266.14 CBY24386.1 - 0.018 14.9 7.5 0.018 14.9 7.5 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) COQ7 PF03232.13 CBY24388.1 - 5.6e-70 234.6 0.6 6.4e-70 234.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 CBY24388.1 - 0.0024 18.2 0.2 0.007 16.8 0.2 1.8 1 1 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.6 CBY24388.1 - 0.016 15.4 0.2 0.073 13.3 0.0 2.0 1 1 1 2 2 2 0 Ferritin-like domain DUF3730 PF12530.8 CBY24388.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) RPAP2_Rtr1 PF04181.13 CBY24389.1 - 1.8e-18 66.6 1.4 3.1e-18 65.8 1.4 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family zf-H2C2_2 PF13465.6 CBY24390.1 - 2.6e-22 78.2 33.6 1.4e-07 31.6 3.9 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY24390.1 - 3.2e-21 74.5 43.2 1.9e-07 31.1 3.5 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY24390.1 - 1.1e-18 66.3 37.2 4.8e-05 23.8 2.1 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY24390.1 - 5.6e-09 36.0 25.5 0.0014 18.8 0.8 5.0 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY24390.1 - 2.5e-08 33.7 31.7 0.00014 21.8 1.9 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 CBY24390.1 - 1.1e-07 32.0 28.3 0.0014 18.9 1.9 5.2 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-BED PF02892.15 CBY24390.1 - 7.1e-05 22.7 27.2 0.0011 18.9 3.2 4.7 3 1 2 5 5 5 2 BED zinc finger zf-Di19 PF05605.12 CBY24390.1 - 0.00021 21.5 22.6 0.00096 19.4 5.1 3.8 2 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 CBY24390.1 - 0.00077 19.3 12.7 5.6 7.0 0.1 5.1 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.7 CBY24390.1 - 0.0012 19.2 22.8 0.24 11.8 4.7 4.3 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 CBY24390.1 - 0.0019 18.3 13.6 0.74 10.0 0.6 4.3 3 1 1 4 4 4 2 Zinc ribbon domain Elf1 PF05129.13 CBY24390.1 - 0.0039 17.2 19.3 0.099 12.7 2.1 4.1 1 1 3 4 4 4 2 Transcription elongation factor Elf1 like Zf_RING PF16744.5 CBY24390.1 - 0.0044 17.1 19.5 1.1 9.4 0.2 5.1 2 1 3 5 5 5 2 KIAA1045 RING finger zf-C2H2_9 PF16293.5 CBY24390.1 - 0.0068 16.2 8.0 1.8 8.5 0.1 4.3 3 1 1 4 4 4 1 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 CBY24390.1 - 0.0069 17.1 10.6 0.49 11.2 0.8 3.1 1 1 0 3 3 3 2 zinc-ribbon family zf-AN1 PF01428.16 CBY24390.1 - 0.0082 16.3 21.5 2.2 8.5 1.6 5.3 4 1 1 5 5 5 1 AN1-like Zinc finger FYVE PF01363.21 CBY24390.1 - 0.021 15.0 24.2 0.39 10.9 10.8 3.5 2 1 1 3 3 3 0 FYVE zinc finger Yippee-Mis18 PF03226.14 CBY24390.1 - 0.025 14.8 1.9 0.025 14.8 1.9 3.1 1 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PyrI_C PF02748.15 CBY24390.1 - 0.089 12.7 8.7 8.4 6.4 0.0 4.2 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HalOD2 PF18547.1 CBY24390.1 - 0.11 12.4 0.9 7.1 6.6 0.1 2.7 3 0 0 3 3 3 0 Halobacterial output domain 2 zf_UBZ PF18439.1 CBY24390.1 - 0.13 11.8 12.3 9.8 5.9 0.2 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 CBY24390.1 - 0.16 11.9 22.1 3.2 7.8 0.6 4.9 5 0 0 5 5 4 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 CBY24390.1 - 0.17 12.4 16.6 1.4 9.5 0.2 5.2 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain HNH_5 PF14279.6 CBY24390.1 - 0.19 11.6 13.0 13 5.7 0.8 4.8 4 1 0 4 4 4 0 HNH endonuclease XPA_N PF01286.18 CBY24390.1 - 0.22 11.6 16.4 6.8 6.8 0.1 5.2 5 0 0 5 5 5 0 XPA protein N-terminal Rad50_zn_hook PF04423.14 CBY24390.1 - 0.26 11.2 4.6 1.7 8.6 0.0 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf_ZIC PF18366.1 CBY24390.1 - 0.32 11.1 16.8 0.68 10.1 0.5 4.3 2 1 2 4 4 4 0 Zic proteins zinc finger domain HypA PF01155.19 CBY24390.1 - 0.34 10.9 10.2 4.6 7.3 6.8 3.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LIM PF00412.22 CBY24390.1 - 0.38 11.0 18.0 7.5 6.9 0.7 4.7 2 1 3 5 5 5 0 LIM domain BolA PF01722.18 CBY24390.1 - 0.47 10.8 4.9 4.7 7.6 0.2 2.9 2 2 1 3 3 3 0 BolA-like protein RNA_POL_M_15KD PF02150.16 CBY24390.1 - 0.5 10.3 0.0 0.5 10.3 0.0 3.7 4 1 1 5 5 5 0 RNA polymerases M/15 Kd subunit zf-C4_ClpX PF06689.13 CBY24390.1 - 0.5 10.3 8.5 3.5 7.6 0.2 3.5 3 0 0 3 3 3 0 ClpX C4-type zinc finger zf-C2H2_3rep PF18868.1 CBY24390.1 - 0.59 10.8 17.7 35 5.1 10.4 4.5 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 CBY24390.1 - 0.66 10.0 11.8 13 5.9 0.1 3.9 2 1 1 3 3 3 0 CpXC protein zf-CHCC PF10276.9 CBY24390.1 - 0.69 10.0 9.2 3 8.0 0.1 3.4 4 0 0 4 4 3 0 Zinc-finger domain GAGA PF09237.11 CBY24390.1 - 0.72 9.7 11.4 0.89 9.4 0.2 3.6 3 2 0 3 3 3 0 GAGA factor zf-MYST PF17772.1 CBY24390.1 - 0.85 9.3 9.8 12 5.6 0.0 4.1 4 0 0 4 4 4 0 MYST family zinc finger domain zf-WRNIP1_ubi PF18279.1 CBY24390.1 - 0.96 10.2 0.0 0.96 10.2 0.0 3.4 4 0 0 4 4 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DpnI PF06044.12 CBY24390.1 - 1.9 8.1 8.1 0.77 9.4 0.3 2.9 1 1 2 3 3 3 0 Dam-replacing family DUF3268 PF11672.8 CBY24390.1 - 2.1 8.7 8.5 1.3 9.4 1.0 3.0 2 2 1 3 3 3 0 zinc-finger-containing domain DUF2256 PF10013.9 CBY24390.1 - 3.9 7.7 17.2 18 5.6 0.1 4.9 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) AA_permease_2 PF13520.6 CBY24391.1 - 1.3e-53 182.3 39.9 1.6e-53 182.1 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY24391.1 - 1.3e-18 66.9 35.7 4.5e-18 65.1 36.0 1.7 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 CBY24392.1 - 7.7e-32 110.7 0.0 1.3e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24392.1 - 2.3e-22 79.6 0.0 4e-22 78.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY24392.1 - 0.0034 16.2 0.4 0.016 14.0 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase FTA2 PF13095.6 CBY24392.1 - 0.035 13.7 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 CBY24392.1 - 0.066 12.8 0.1 0.23 11.0 0.0 1.9 2 1 0 2 2 2 0 Choline/ethanolamine kinase NDK PF00334.19 CBY24393.1 - 4.5e-91 301.9 0.2 6.8e-32 110.3 0.0 3.2 2 1 1 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.20 CBY24393.1 - 7.4e-06 25.9 0.0 2.2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin Arg_repressor PF01316.21 CBY24393.1 - 0.01 15.6 1.2 1.3 8.8 0.1 3.4 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain IlvN PF07991.12 CBY24393.1 - 0.022 14.4 0.4 0.8 9.3 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF3939 PF13075.6 CBY24394.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) DUF1987 PF09345.10 CBY24394.1 - 1.9 8.2 6.1 13 5.5 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF1987) DnaI_N PF07319.11 CBY24397.1 - 0.025 15.2 0.4 0.37 11.5 0.1 3.3 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus DUF3398 PF11878.8 CBY24397.1 - 0.36 11.3 3.2 2.6 8.5 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3398) SOBP PF15279.6 CBY24399.1 - 2 8.9 9.0 2.9 8.4 9.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein rve PF00665.26 CBY24400.1 - 0.00015 22.0 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain SH3_15 PF18346.1 CBY24400.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain rve_3 PF13683.6 CBY24400.1 - 0.12 12.1 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain Pkinase_Tyr PF07714.17 CBY24401.1 - 2.7e-68 230.1 0.0 3e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY24401.1 - 4e-33 114.9 0.0 5.9e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY24401.1 - 4.5e-06 26.2 0.0 7.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBY24401.1 - 0.00075 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY24401.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family UPF0128 PF03673.13 CBY24401.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0128) Peptidase_M1 PF01433.20 CBY24404.1 - 3.3e-49 167.4 0.1 4.4e-49 167.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY24404.1 - 5.6e-29 101.7 0.0 9.2e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DnaJ PF00226.31 CBY24405.1 - 7.3e-17 61.3 1.9 9.3e-17 60.9 1.9 1.1 1 0 0 1 1 1 1 DnaJ domain Trypsin PF00089.26 CBY24407.1 - 3.6e-42 144.6 0.5 5.2e-42 144.1 0.5 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY24407.1 - 4.1e-09 37.5 0.0 8.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY24407.1 - 0.00029 20.5 0.5 0.23 11.0 0.0 2.7 3 0 0 3 3 3 2 Chymotrypsin family Peptidase-S1 Trypsin PF00089.26 CBY24408.1 - 2.5e-42 145.2 0.7 3.8e-42 144.6 0.7 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY24408.1 - 2.9e-09 38.0 0.0 5.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY24408.1 - 0.00047 19.8 0.0 0.18 11.3 0.0 2.6 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 Pkinase PF00069.25 CBY24409.1 - 9.8e-34 116.9 0.0 1.8e-33 116.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24409.1 - 1.8e-09 37.3 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY24409.1 - 4.4e-09 36.0 0.0 7.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY24409.1 - 7.2e-05 22.2 0.0 9.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY24409.1 - 0.00018 21.5 0.0 0.00033 20.7 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY24409.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CBY24409.1 - 0.002 17.2 0.2 0.019 13.9 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBY24409.1 - 0.011 15.3 0.2 0.085 12.5 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 CBY24409.1 - 0.012 14.4 0.0 0.028 13.2 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Uds1 PF15456.6 CBY24410.1 - 0.00087 19.5 2.1 0.0015 18.7 2.1 1.3 1 0 0 1 1 1 1 Up-regulated During Septation NRBF2 PF08961.10 CBY24412.1 - 0.0082 15.8 0.4 0.0082 15.8 0.4 2.0 2 1 0 3 3 3 1 Nuclear receptor-binding factor 2, autophagy regulator Pet191_N PF10203.9 CBY24413.1 - 1.9e-07 31.3 1.2 2.9e-07 30.7 1.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PilW PF16074.5 CBY24413.1 - 0.0062 16.6 0.7 0.15 12.1 0.1 2.1 2 0 0 2 2 2 2 Type IV Pilus-assembly protein W Methyltr_RsmB-F PF01189.17 CBY24414.1 - 2.8e-12 46.7 0.0 4.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBY24414.1 - 0.00012 22.3 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 CBY24414.1 - 0.00044 20.9 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PUA PF01472.20 CBY24414.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 PUA domain Methyltransf_11 PF08241.12 CBY24414.1 - 0.093 13.4 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Dus PF01207.17 CBY24415.1 - 2.2e-55 187.9 0.1 4.2e-55 187.0 0.1 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CBY24415.1 - 0.004 16.6 0.1 0.0079 15.7 0.1 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein PA28_alpha PF02251.18 CBY24415.1 - 0.023 14.7 0.2 0.083 12.9 0.0 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit BKACE PF05853.12 CBY24415.1 - 0.087 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme KH_1 PF00013.29 CBY24416.1 - 0.0025 17.6 1.0 0.0044 16.8 1.0 1.4 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 CBY24416.1 - 0.082 13.0 0.1 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Krr1 KH1 domain TctA PF01970.16 CBY24416.1 - 0.19 10.4 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family PRKCSH PF07915.13 CBY24417.1 - 8.8e-13 49.1 0.2 1.2e-12 48.6 0.2 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein NDUF_C2 PF06374.11 CBY24418.1 - 0.051 13.7 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) ANAPC4_WD40 PF12894.7 CBY24419.1 - 3.8e-23 81.6 1.4 1.4e-05 25.3 0.0 6.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY24419.1 - 1.4e-21 76.4 11.8 0.00018 22.2 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 CBY24419.1 - 5.3e-06 25.2 0.4 0.0024 16.5 0.4 2.4 1 1 2 3 3 3 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 CBY24419.1 - 0.00037 19.7 0.0 0.18 10.8 0.0 2.7 1 1 1 3 3 3 2 Coatomer WD associated region Nup160 PF11715.8 CBY24419.1 - 0.0018 17.0 0.1 0.0049 15.6 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 CBY24419.1 - 0.002 17.0 2.2 2.4 6.8 0.0 3.5 2 1 1 3 3 3 2 Prolyl oligopeptidase, N-terminal beta-propeller domain IKI3 PF04762.12 CBY24419.1 - 0.0074 14.3 0.1 0.21 9.6 0.1 2.7 2 1 0 2 2 2 1 IKI3 family Me-amine-dh_H PF06433.11 CBY24419.1 - 0.038 12.8 0.0 0.58 9.0 0.0 2.7 2 1 1 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) PD40 PF07676.12 CBY24419.1 - 0.18 11.8 0.0 47 4.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Connexin PF00029.19 CBY24420.1 - 6.6e-84 281.3 2.9 8.5e-84 281.0 2.9 1.1 1 0 0 1 1 1 1 Connexin DUF2207 PF09972.9 CBY24420.1 - 0.085 11.6 8.9 1 8.1 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) GMC_oxred_N PF00732.19 CBY24421.1 - 1.5e-84 283.9 0.0 1.9e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CBY24421.1 - 8.7e-39 133.3 0.0 1.4e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HRM PF02793.22 CBY24421.1 - 5.8e-05 23.3 0.9 0.00012 22.3 0.9 1.5 1 0 0 1 1 1 1 Hormone receptor domain Lycopene_cycl PF05834.12 CBY24421.1 - 7.7e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein 7tm_2 PF00002.24 CBY24421.1 - 0.00027 20.3 2.8 0.00042 19.7 2.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DAO PF01266.24 CBY24421.1 - 0.00085 19.0 0.1 0.0039 16.8 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase SUR7 PF06687.12 CBY24421.1 - 0.0017 18.0 0.1 0.0034 17.0 0.1 1.4 1 0 0 1 1 1 1 SUR7/PalI family Pyr_redox_3 PF13738.6 CBY24421.1 - 0.0071 15.6 0.0 0.67 9.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY24421.1 - 0.017 14.2 0.0 0.57 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 CBY24421.1 - 0.019 14.2 0.0 0.46 9.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Claudin_3 PF06653.11 CBY24421.1 - 0.02 14.8 1.9 0.033 14.1 1.9 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like NAD_binding_8 PF13450.6 CBY24421.1 - 0.031 14.5 0.1 0.073 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CBY24421.1 - 0.12 11.0 0.0 0.91 8.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein 7tm_2 PF00002.24 CBY24422.1 - 1.2e-11 44.4 0.8 1.7e-11 43.9 0.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Chordopox_A13L PF05961.11 CBY24422.1 - 0.0022 18.2 0.6 0.0022 18.2 0.6 3.0 3 0 0 3 3 3 1 Chordopoxvirus A13L protein DUF2794 PF10984.8 CBY24422.1 - 0.031 14.4 0.2 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2794) 7tm_7 PF08395.12 CBY24422.1 - 0.039 13.1 2.4 0.26 10.4 0.0 2.1 1 1 1 2 2 2 0 7tm Chemosensory receptor YcbB PF08664.10 CBY24422.1 - 0.12 12.4 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 YcbB domain LapA_dom PF06305.11 CBY24422.1 - 0.12 12.2 0.3 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 CBY24422.1 - 5.5 6.8 14.3 0.044 13.5 1.6 3.2 3 1 1 4 4 4 0 Vpu protein AA_permease_2 PF13520.6 CBY24423.1 - 7.3e-57 193.1 39.4 9.1e-57 192.8 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY24423.1 - 5.7e-27 94.5 36.5 7.7e-27 94.0 36.5 1.2 1 0 0 1 1 1 1 Amino acid permease OppC_N PF12911.7 CBY24424.1 - 0.061 13.3 0.2 0.085 12.9 0.2 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C EF-hand_1 PF00036.32 CBY24425.1 - 1.8e-19 67.7 7.4 3.1e-07 29.4 0.1 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 CBY24425.1 - 3.2e-19 69.1 5.5 6.8e-10 39.3 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY24425.1 - 2.7e-17 61.1 11.1 0.00014 21.5 0.2 5.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 CBY24425.1 - 1.7e-10 39.9 6.0 0.0044 16.5 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY24425.1 - 1.6e-09 37.5 9.9 8.8e-06 25.5 0.2 4.6 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.6 CBY24425.1 - 0.014 15.7 0.2 1.9 8.9 0.0 3.1 3 1 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY24425.1 - 0.016 15.5 0.4 0.18 12.2 0.2 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Kelch_4 PF13418.6 CBY24426.1 - 0.061 13.3 0.3 2.5 8.2 0.0 2.5 1 1 1 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY24426.1 - 0.083 12.9 0.4 0.43 10.6 0.2 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CBY24426.1 - 0.1 12.2 0.1 0.1 12.2 0.1 2.1 3 0 0 3 3 3 0 Kelch motif LCM PF04072.14 CBY24427.1 - 8.7e-29 100.8 0.0 9.7e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TPR_2 PF07719.17 CBY24428.1 - 7.2e-19 66.3 6.7 0.0089 16.1 0.0 7.1 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBY24428.1 - 2.3e-18 65.2 6.7 0.00027 20.6 0.0 7.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY24428.1 - 7.2e-14 50.8 8.9 0.00012 22.0 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY24428.1 - 3.9e-11 43.3 0.9 0.00038 20.9 0.0 4.5 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY24428.1 - 1.2e-10 41.3 0.7 0.13 13.2 0.0 5.9 4 3 2 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY24428.1 - 3.9e-10 39.9 3.7 0.032 14.5 0.3 5.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY24428.1 - 1.3e-09 38.5 0.1 0.11 13.2 0.0 4.0 3 2 1 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBY24428.1 - 1.6e-09 37.5 4.5 0.019 15.3 0.0 5.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBY24428.1 - 7.1e-07 28.8 1.9 0.072 12.8 0.0 4.3 4 1 1 5 5 4 2 TPR repeat TPR_6 PF13174.6 CBY24428.1 - 1.1e-06 28.9 8.9 1.2 9.9 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY24428.1 - 3.6e-05 23.5 0.2 13 6.1 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY24428.1 - 6.2e-05 23.1 0.4 0.062 13.5 0.0 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat PknG_TPR PF16918.5 CBY24428.1 - 0.00083 18.2 0.2 0.0062 15.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_10 PF13374.6 CBY24428.1 - 0.0015 18.3 0.2 0.99 9.4 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY24428.1 - 0.0025 18.0 7.2 0.11 12.7 0.4 3.7 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.23 CBY24428.1 - 0.046 12.9 3.8 0.56 9.4 2.3 2.9 2 1 0 2 2 2 0 FAT domain TPR_4 PF07721.14 CBY24428.1 - 0.049 14.3 0.5 88 4.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 CBY24428.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4810 PF16068.5 CBY24428.1 - 0.16 12.5 5.2 21 5.7 0.1 4.8 5 1 0 5 5 4 0 Domain of unknown function (DUF4810) Swi3 PF07962.12 CBY24429.1 - 2.7e-20 72.2 0.6 5.8e-20 71.1 0.6 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 eIF3_subunit PF08597.10 CBY24429.1 - 0.13 12.1 20.4 0.52 10.2 0.3 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Nop14 PF04147.12 CBY24429.1 - 1 7.5 23.9 0.043 12.0 17.2 1.8 2 0 0 2 2 2 0 Nop14-like family TH1 PF04858.13 CBY24430.1 - 2.6e-81 274.0 0.2 3e-81 273.8 0.2 1.0 1 0 0 1 1 1 1 TH1 protein Pkinase PF00069.25 CBY24433.1 - 4.6e-57 193.4 0.0 7.6e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24433.1 - 1.7e-28 99.6 0.0 2.7e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY24433.1 - 0.00023 20.2 1.1 0.013 14.4 1.1 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY24433.1 - 0.055 12.8 0.1 0.21 10.9 0.1 1.9 1 1 1 2 2 2 0 Kinase-like Zip PF02535.22 CBY24433.1 - 0.23 10.6 1.2 0.37 9.9 1.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RIO1 PF01163.22 CBY24433.1 - 0.72 9.4 0.0 0.72 9.4 0.0 2.5 3 0 0 3 3 3 0 RIO1 family MCM_bind PF09739.9 CBY24433.1 - 3 6.2 9.6 4.8 5.5 9.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Nucleo_P87 PF07267.11 CBY24433.1 - 3.2 6.5 13.5 4.7 5.9 13.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SSF PF00474.17 CBY24434.1 - 2.1e-32 112.5 22.4 2.7e-32 112.1 22.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3328 PF11807.8 CBY24434.1 - 0.036 13.8 0.2 0.036 13.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Cytochrom_B_N_2 PF13631.6 CBY24434.1 - 0.24 11.4 5.5 22 5.0 0.3 3.8 4 0 0 4 4 4 0 Cytochrome b(N-terminal)/b6/petB DUF3493 PF11998.8 CBY24434.1 - 0.96 9.7 8.2 12 6.1 0.4 4.2 3 1 1 4 4 4 0 Low psii accumulation1 / Rep27 DUF2214 PF09980.9 CBY24436.1 - 0.018 14.8 0.5 0.02 14.7 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) Carboxyl_trans PF01039.22 CBY24437.1 - 8.7e-193 641.4 0.5 1e-192 641.2 0.5 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBY24437.1 - 0.039 13.4 0.0 0.039 13.4 0.0 2.7 3 0 0 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) V_ATPase_I PF01496.19 CBY24438.1 - 0.0062 14.5 9.3 0.0069 14.4 9.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CUTL PF16557.5 CBY24438.1 - 0.049 13.8 0.3 0.098 12.9 0.2 1.6 1 1 0 1 1 1 0 CUT1-like DNA-binding domain of SATB Laminin_I PF06008.14 CBY24438.1 - 0.084 12.6 15.1 0.083 12.6 12.7 1.8 1 1 1 2 2 2 0 Laminin Domain I PIN_8 PF18476.1 CBY24438.1 - 0.17 11.7 7.6 0.23 11.3 7.6 1.3 1 0 0 1 1 1 0 PIN like domain UPF0449 PF15136.6 CBY24438.1 - 0.6 10.6 5.5 0.32 11.5 3.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 UPF0242 PF06785.11 CBY24438.1 - 1.9 8.6 14.3 0.14 12.2 7.5 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 CBY24438.1 - 5.2 7.5 13.9 11 6.5 10.5 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.11 CBY24439.1 - 1.4 7.7 68.8 1.6 7.5 22.6 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein MtrB PF05440.12 CBY24439.1 - 1.7 9.2 3.3 2.6 8.5 0.1 2.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B YgbB PF02542.16 CBY24439.1 - 1.8 8.9 9.0 0.67 10.2 0.6 3.7 2 1 1 4 4 4 0 YgbB family MbeD_MobD PF04899.12 CBY24439.1 - 5.2 7.3 29.0 2.1 8.5 2.7 6.3 5 2 1 6 6 6 0 MbeD/MobD like Tubulin PF00091.25 CBY24440.1 - 1.8e-69 233.9 0.0 2.9e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY24440.1 - 1.4e-40 138.3 0.0 2.2e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY24440.1 - 4.4e-06 27.0 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBY24440.1 - 0.0057 16.4 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBY24440.1 - 0.018 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Ras PF00071.22 CBY24441.1 - 7.5e-55 185.0 0.5 9e-55 184.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY24441.1 - 2e-30 105.4 0.1 3.5e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY24441.1 - 3.9e-15 55.7 0.3 5.1e-15 55.4 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY24441.1 - 7.2e-07 28.8 0.5 9e-07 28.5 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY24441.1 - 5e-05 23.4 0.1 8.7e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY24441.1 - 0.00015 22.0 0.0 0.00047 20.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBY24441.1 - 0.0004 20.3 0.7 0.25 11.2 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY24441.1 - 0.0062 16.1 0.6 0.013 15.1 0.6 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CBY24441.1 - 0.0071 16.1 0.1 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 CBY24441.1 - 0.0076 15.7 0.2 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 CBY24441.1 - 0.0087 16.1 0.1 0.026 14.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY24441.1 - 0.015 15.7 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 CBY24441.1 - 0.019 14.7 0.1 2.1 8.1 0.0 2.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 CBY24441.1 - 0.043 14.0 0.0 0.075 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain CENP-M PF11111.8 CBY24441.1 - 0.046 12.9 0.4 0.095 11.9 0.1 1.6 2 0 0 2 2 2 0 Centromere protein M (CENP-M) AAA_7 PF12775.7 CBY24441.1 - 0.058 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region LolA PF03548.15 CBY24441.1 - 0.063 13.0 0.5 0.12 12.1 0.3 1.6 1 1 1 2 2 2 0 Outer membrane lipoprotein carrier protein LolA NACHT PF05729.12 CBY24441.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FtsX_ECD PF18075.1 CBY24442.1 - 0.029 15.0 0.3 0.066 13.8 0.3 1.6 1 0 0 1 1 1 0 FtsX extracellular domain OKR_DC_1_N PF03709.15 CBY24442.1 - 0.11 12.7 0.0 0.48 10.7 0.1 2.1 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain AXH PF08517.12 CBY24443.1 - 3.8e-29 101.6 0.2 1.1e-28 100.0 0.1 1.9 2 0 0 2 2 2 1 Ataxin-1 and HBP1 module (AXH) Hint PF01079.20 CBY24443.1 - 0.04 13.4 0.2 0.1 12.1 0.2 1.7 1 1 0 1 1 1 0 Hint module Vint PF14623.6 CBY24443.1 - 0.24 11.2 0.0 0.24 11.2 0.0 2.3 3 0 0 3 3 3 0 Hint-domain DUF2729 PF10870.8 CBY24444.1 - 0.59 10.0 3.2 1.9 8.4 3.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) WDCP PF15390.6 CBY24444.1 - 3.3 6.0 6.5 5.6 5.2 6.5 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family G_path_suppress PF15991.5 CBY24446.1 - 2.6 8.1 12.9 2.9 7.9 12.9 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor VIR_N PF15912.5 CBY24446.1 - 9.4 5.7 12.2 12 5.4 12.2 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Zip PF02535.22 CBY24447.1 - 3.3e-31 108.8 22.9 1.1e-23 84.0 14.0 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter DUF996 PF06195.13 CBY24447.1 - 0.028 14.7 0.9 0.028 14.7 0.9 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF996) BaxI_1 PF12811.7 CBY24447.1 - 0.53 9.8 5.1 0.9 9.1 4.7 1.6 1 1 0 1 1 1 0 Bax inhibitor 1 like Mss4 PF04421.13 CBY24448.1 - 5.4e-22 77.7 0.0 7e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein SPC12 PF06645.13 CBY24449.1 - 2.6e-23 81.9 0.1 3.4e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Acyltransferase PF01553.21 CBY24450.1 - 1.6e-20 73.1 0.0 5.1e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase NACHT PF05729.12 CBY24451.1 - 9.6e-10 38.6 0.0 1.1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CBY24451.1 - 0.0028 17.9 0.0 0.0036 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CBY24451.1 - 0.019 15.4 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FAS_N PF17828.1 CBY24453.1 - 0.19 11.8 0.0 0.86 9.6 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta Y_phosphatase PF00102.27 CBY24454.1 - 3.2e-124 413.1 4.8 4.7e-70 235.8 1.3 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Sushi PF00084.20 CBY24454.1 - 3.1e-51 171.8 94.6 8.5e-06 26.3 2.1 13.7 13 0 0 13 13 13 12 Sushi repeat (SCR repeat) Mucin2_WxxW PF13330.6 CBY24454.1 - 1.1e-12 48.6 4.7 1.1e-12 48.6 4.7 4.8 3 2 1 4 4 4 1 Mucin-2 protein WxxW repeating region Ricin_B_lectin PF00652.22 CBY24454.1 - 8.3e-07 29.3 0.9 3.4e-06 27.3 0.9 2.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DSPc PF00782.20 CBY24454.1 - 0.00041 20.2 0.5 0.28 11.0 0.1 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain DUF3377 PF11857.8 CBY24454.1 - 0.011 15.6 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) HAP1_N PF04849.13 CBY24454.1 - 0.43 9.7 2.1 7.5 5.7 0.0 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Complex1_LYR PF05347.15 CBY24455.1 - 6.4e-09 35.7 0.9 4.2e-08 33.1 0.1 2.0 1 1 1 2 2 2 1 Complex 1 protein (LYR family) UDPG_MGDP_dh_N PF03721.14 CBY24456.1 - 1.3e-63 213.9 0.0 2e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 CBY24456.1 - 3.8e-35 120.5 0.0 6e-34 116.6 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 CBY24456.1 - 5.4e-31 106.7 0.1 1.1e-30 105.6 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 CBY24456.1 - 0.083 13.2 0.3 0.41 10.9 0.0 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Solute_trans_a PF03619.16 CBY24457.1 - 1.7e-92 309.7 14.8 2.1e-92 309.4 14.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Methyltr_RsmB-F PF01189.17 CBY24458.1 - 1.8e-13 50.6 0.0 2e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F API5 PF05918.11 CBY24458.1 - 0.014 14.3 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TFIIA PF03153.13 CBY24459.1 - 0.38 10.7 13.4 0.52 10.2 13.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Forkhead PF00250.18 CBY24460.1 - 3.7e-34 116.9 0.1 5.7e-34 116.2 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain SOG2 PF10428.9 CBY24461.1 - 1.3 8.1 23.8 2.3 7.3 23.8 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein KAR9 PF08580.10 CBY24461.1 - 1.8 7.0 16.1 1.9 6.9 16.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SWI-SNF_Ssr4 PF08549.10 CBY24461.1 - 5 5.6 16.2 6.2 5.3 16.2 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Gal11_ABD1 PF18535.1 CBY24462.1 - 0.011 15.8 0.2 0.016 15.3 0.2 1.3 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) NMD3 PF04981.13 CBY24463.1 - 4e-72 242.6 3.5 6.2e-72 242.0 3.5 1.3 1 0 0 1 1 1 1 NMD3 family Raptor_N PF14538.6 CBY24464.1 - 1.5e-47 161.3 0.3 5.1e-47 159.5 0.1 2.1 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CBY24464.1 - 0.00072 19.6 0.1 0.057 13.7 0.0 3.8 5 0 0 5 5 5 1 HEAT repeat WD40 PF00400.32 CBY24464.1 - 0.015 16.2 0.8 1.8 9.6 0.1 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat HEAT_2 PF13646.6 CBY24464.1 - 0.066 13.6 0.0 0.39 11.2 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 CBY24464.1 - 0.084 13.4 0.0 0.68 10.5 0.0 2.6 3 0 0 3 3 3 0 HEAT-like repeat Ribosomal_L1 PF00687.21 CBY24465.1 - 6.5e-35 120.7 1.3 6.5e-35 120.7 1.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family RR_TM4-6 PF06459.12 CBY24465.1 - 1.1 9.1 18.3 2 8.2 18.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 CBY24465.1 - 4.2 6.2 11.3 6.3 5.6 11.3 1.3 1 0 0 1 1 1 0 Xrn1 helical domain DDHD PF02862.17 CBY24465.1 - 4.3 7.4 8.4 7.9 6.6 8.4 1.4 1 0 0 1 1 1 0 DDHD domain GNT-I PF03071.15 CBY24466.1 - 8.5e-48 163.2 0.3 1.9e-47 162.0 0.3 1.5 1 1 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 CBY24466.1 - 2.2e-06 27.8 0.2 1.3e-05 25.2 0.2 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 MGAT2 PF05060.14 CBY24466.1 - 0.00064 18.9 0.0 0.53 9.3 0.0 2.2 2 0 0 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) Glycos_transf_2 PF00535.26 CBY24466.1 - 0.0096 15.7 0.0 0.028 14.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ocnus PF05005.15 CBY24467.1 - 6.3e-30 103.5 0.0 1.4e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) tRNA_SAD PF07973.14 CBY24467.1 - 2.9e-09 36.8 1.9 3.6e-09 36.6 0.2 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 CBY24467.1 - 3.9e-08 32.3 0.0 6.5e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) Yippee-Mis18 PF03226.14 CBY24468.1 - 0.00011 22.4 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 CBY24468.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.5 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Rootletin PF15035.6 CBY24470.1 - 3.3e-37 128.4 34.4 3.3e-37 128.4 34.4 14.0 3 1 9 13 13 13 3 Ciliary rootlet component, centrosome cohesion SOGA PF11365.8 CBY24470.1 - 0.006 17.7 8.4 0.006 17.7 8.4 19.9 6 4 14 21 21 21 2 Protein SOGA KELK PF15796.5 CBY24470.1 - 0.0094 16.4 0.9 0.0094 16.4 0.9 21.5 10 6 12 22 22 22 3 KELK-motif containing domain of MRCK Ser/Thr protein kinase A_deaminase PF00962.22 CBY24472.1 - 7.5e-78 262.1 0.0 8.8e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 CBY24472.1 - 0.0042 16.4 0.1 0.0065 15.8 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family LisH_TPL PF17814.1 CBY24472.1 - 0.091 12.4 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 LisH-like dimerisation domain Aa_trans PF01490.18 CBY24473.1 - 9e-37 126.7 24.2 6.4e-30 104.2 15.1 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein CDI PF02234.19 CBY24474.1 - 8e-12 45.2 2.1 1.8e-11 44.1 2.1 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor WAPL PF07814.13 CBY24474.1 - 0.045 12.5 0.1 0.067 12.0 0.1 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Filament PF00038.21 CBY24475.1 - 0.0021 17.7 9.5 0.0041 16.7 9.5 1.5 1 1 0 1 1 1 1 Intermediate filament protein BST2 PF16716.5 CBY24475.1 - 0.0044 17.6 1.6 0.0044 17.6 1.6 2.5 2 1 1 3 3 2 1 Bone marrow stromal antigen 2 IMD PF08397.11 CBY24475.1 - 0.006 16.0 2.2 0.0082 15.5 2.2 1.4 1 0 0 1 1 1 1 IRSp53/MIM homology domain HMMR_N PF15905.5 CBY24475.1 - 0.0086 15.6 5.7 0.0086 15.6 5.7 1.5 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF4201 PF13870.6 CBY24475.1 - 0.028 14.2 8.0 0.041 13.6 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) EzrA PF06160.12 CBY24475.1 - 0.034 12.3 4.6 0.048 11.8 4.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Atg14 PF10186.9 CBY24475.1 - 0.054 12.6 4.3 0.067 12.3 4.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SNAD2 PF18745.1 CBY24475.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.6 1 1 1 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 2 MCPsignal PF00015.21 CBY24475.1 - 0.066 13.0 1.2 1.2 8.9 0.1 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GAS PF13851.6 CBY24475.1 - 0.092 12.1 9.3 0.16 11.3 9.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 CBY24475.1 - 0.1 11.9 11.8 0.05 12.9 6.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Par3_HAL_N_term PF12053.8 CBY24475.1 - 0.11 12.7 0.1 0.29 11.3 0.0 1.7 1 1 0 1 1 1 0 N-terminal of Par3 and HAL proteins HBS1_N PF08938.10 CBY24475.1 - 0.21 11.9 1.7 0.32 11.3 1.3 1.6 1 1 0 1 1 1 0 HBS1 N-terminus DUF1664 PF07889.12 CBY24475.1 - 0.23 11.5 4.8 0.25 11.4 0.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Lipase_chap PF03280.14 CBY24475.1 - 0.25 11.3 13.6 0.72 9.8 4.7 2.2 1 1 1 2 2 2 0 Proteobacterial lipase chaperone protein UPF0242 PF06785.11 CBY24475.1 - 0.3 11.2 11.2 0.41 10.7 11.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 CBY24475.1 - 0.31 11.4 5.8 0.83 10.0 3.1 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4763 PF15960.5 CBY24475.1 - 0.44 9.8 11.3 1.9 7.7 11.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Uds1 PF15456.6 CBY24475.1 - 0.46 10.7 8.4 0.11 12.6 5.1 1.7 2 0 0 2 2 1 0 Up-regulated During Septation V-SNARE PF05008.15 CBY24475.1 - 1 9.8 7.7 0.7 10.3 4.9 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spc7 PF08317.11 CBY24475.1 - 1.4 7.7 13.1 0.18 10.6 8.7 1.7 2 1 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 CBY24475.1 - 1.5 9.3 13.6 0.28 11.6 2.0 2.2 1 1 1 2 2 2 0 Fez1 APG6_N PF17675.1 CBY24475.1 - 2 9.0 10.9 0.18 12.3 1.2 2.4 1 1 0 2 2 2 0 Apg6 coiled-coil region Fungal_TACC PF12709.7 CBY24475.1 - 2.1 8.8 7.4 5.1 7.6 0.9 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMPIT PF07851.13 CBY24475.1 - 2.4 7.3 6.5 8.9 5.4 1.1 2.0 1 1 0 2 2 2 0 TMPIT-like protein DUF5624 PF18538.1 CBY24475.1 - 2.8 8.0 5.3 24 5.0 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5624) Sec8_exocyst PF04048.14 CBY24475.1 - 2.9 7.8 7.0 27 4.7 7.0 2.3 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain CENP-H PF05837.12 CBY24475.1 - 5.9 7.3 11.2 0.2 12.1 3.4 2.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) FUSC PF04632.12 CBY24475.1 - 6.2 5.2 6.2 7.3 5.0 6.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 CBY24475.1 - 6.8 6.7 12.6 1.3 9.1 8.0 2.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FadA PF09403.10 CBY24475.1 - 6.9 7.2 12.4 1.5 9.4 1.3 2.6 3 0 0 3 3 3 0 Adhesion protein FadA zf-3CxxC_2 PF17180.4 CBY24476.1 - 1.7e-19 70.3 10.4 2.8e-19 69.6 10.4 1.3 1 0 0 1 1 1 1 Zinc-binding domain RNA_pol_Rpb2_5 PF04567.17 CBY24476.1 - 0.12 13.0 0.1 2.6 8.7 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 UPF0515 PF15135.6 CBY24476.1 - 0.52 9.6 8.4 0.79 9.0 8.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 GRIM-19 PF06212.12 CBY24477.1 - 1.6e-16 60.4 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 GRIM-19 protein DnaT PF17948.1 CBY24477.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 DnaT DNA-binding domain Cauli_DNA-bind PF03310.13 CBY24477.1 - 0.16 12.0 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein DEAD PF00270.29 CBY24478.1 - 1.5e-40 138.9 0.3 7.8e-40 136.5 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY24478.1 - 1.9e-25 89.3 0.7 4.7e-23 81.6 0.2 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CBY24478.1 - 2.3e-06 27.7 0.1 5e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBY24478.1 - 9.1e-06 25.2 0.1 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit REF PF05755.12 CBY24478.1 - 0.028 14.3 0.1 4.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) DUF5453 PF17534.2 CBY24479.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) DUF2717 PF10911.8 CBY24479.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) Med16 PF11635.8 CBY24481.1 - 0.00079 17.5 1.1 0.00099 17.2 0.3 1.4 1 1 0 1 1 1 1 Mediator complex subunit 16 Herpes_VP19C PF03327.14 CBY24481.1 - 0.053 13.0 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C tRNA_bind PF01588.20 CBY24482.1 - 6.5e-30 103.1 0.4 1.3e-29 102.1 0.4 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain CCD48 PF15799.5 CBY24482.1 - 0.0016 16.9 3.0 0.0021 16.5 3.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 APC_N_CC PF16689.5 CBY24482.1 - 0.016 15.2 0.9 0.062 13.4 0.7 2.1 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DDHD PF02862.17 CBY24482.1 - 0.085 13.0 2.7 0.099 12.8 2.7 1.2 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 CBY24482.1 - 0.12 12.8 10.4 0.24 11.8 10.4 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 CBY24482.1 - 0.15 11.5 7.1 0.18 11.2 7.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CBY24482.1 - 0.84 9.4 17.0 1.2 9.0 17.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XhlA PF10779.9 CBY24482.1 - 0.96 9.7 4.1 0.38 11.0 0.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA YabA PF06156.13 CBY24482.1 - 0.98 10.1 5.5 3.2 8.5 5.5 1.9 1 1 0 1 1 1 0 Initiation control protein YabA GAGA_bind PF06217.12 CBY24482.1 - 1.4 9.1 12.1 1.9 8.7 12.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SKA1 PF07160.12 CBY24482.1 - 1.7 8.4 18.6 2.3 8.0 18.6 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF913 PF06025.12 CBY24482.1 - 1.9 7.4 6.0 2.6 6.9 6.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CBY24482.1 - 2.2 7.0 7.0 2.5 6.8 7.0 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CBY24482.1 - 3 5.6 6.9 3.9 5.3 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tim54 PF11711.8 CBY24482.1 - 3.4 6.4 12.2 5.1 5.8 12.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 CBY24482.1 - 6.2 6.8 6.1 8.8 6.3 6.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Coilin_N PF15862.5 CBY24482.1 - 6.4 6.6 14.7 10 5.9 14.7 1.3 1 0 0 1 1 1 0 Coilin N-terminus GST_N_3 PF13417.6 CBY24483.1 - 4.8e-09 36.5 0.0 1.1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CBY24483.1 - 2e-07 31.1 0.1 5.2e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_N_2 PF13409.6 CBY24483.1 - 3e-05 24.2 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBY24483.1 - 0.00011 22.4 0.0 0.00034 20.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY24483.1 - 0.00024 21.4 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CBY24483.1 - 0.00097 19.1 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CBY24483.1 - 0.0024 18.6 0.0 0.046 14.5 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 CBY24483.1 - 0.012 15.8 0.0 0.037 14.2 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF836 PF05768.14 CBY24483.1 - 0.15 12.5 0.0 0.51 10.8 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) LRR_8 PF13855.6 CBY24484.1 - 2.5e-15 56.0 32.2 5.4e-06 26.1 0.7 4.1 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY24484.1 - 6.3e-13 48.7 37.1 0.00012 22.4 1.4 6.0 2 2 4 6 6 6 4 Leucine Rich repeats (2 copies) Med18 PF09637.10 CBY24484.1 - 0.036 13.9 0.2 0.058 13.2 0.2 1.3 1 0 0 1 1 1 0 Med18 protein H-kinase_dim PF02895.14 CBY24484.1 - 0.047 14.1 1.0 0.1 13.0 0.3 2.0 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain LRR_1 PF00560.33 CBY24484.1 - 0.11 13.1 31.5 4.1 8.3 0.6 8.0 7 1 1 8 8 8 0 Leucine Rich Repeat DUF1835 PF08874.10 CBY24484.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) LRR_6 PF13516.6 CBY24484.1 - 1.7 8.9 20.7 3.8 7.8 0.2 6.3 6 0 0 6 6 6 0 Leucine Rich repeat DUF3381 PF11861.8 CBY24485.1 - 0.61 9.9 17.0 0.45 10.3 15.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF2570 PF10828.8 CBY24485.1 - 6.7 6.6 7.3 1.5 8.7 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Peptidase_S10 PF00450.22 CBY24486.1 - 1.8e-109 366.9 1.0 1.8e-109 366.9 1.0 2.9 3 1 0 3 3 3 1 Serine carboxypeptidase ELL PF10390.9 CBY24486.1 - 2.5e-16 60.0 3.5 2.5e-16 60.0 3.5 2.4 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 CBY24486.1 - 1.6e-09 38.4 24.7 9.3e-09 35.9 5.6 4.1 4 0 0 4 4 4 2 Occludin homology domain DUF2920 PF11144.8 CBY24486.1 - 0.017 14.3 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DASH_Dad2 PF08654.10 CBY24486.1 - 0.54 10.7 0.0 0.54 10.7 0.0 2.5 3 0 0 3 3 3 0 DASH complex subunit Dad2 zf-RING_5 PF14634.6 CBY24488.1 - 2.3e-05 24.2 8.6 2.3e-05 24.2 8.6 2.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY24488.1 - 2.3e-05 24.1 8.9 2.3e-05 24.1 8.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY24488.1 - 7.3e-05 22.7 8.6 7.3e-05 22.7 8.6 2.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY24488.1 - 0.0017 18.6 12.2 0.0017 18.6 12.2 2.8 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY24488.1 - 0.007 16.2 12.3 0.007 16.2 12.3 2.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY24488.1 - 0.0097 16.0 9.6 0.0097 16.0 9.6 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBY24488.1 - 1.5 8.7 15.7 0.43 10.5 9.9 2.9 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 Peptidase_M14 PF00246.24 CBY24489.1 - 2.5e-134 447.6 0.8 1.6e-66 225.1 0.0 2.2 2 0 0 2 2 2 2 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 CBY24489.1 - 3.3e-21 75.3 0.0 6.7e-09 35.9 0.0 3.1 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain AstE_AspA PF04952.14 CBY24489.1 - 5.2e-09 35.6 0.1 5.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family CarbopepD_reg_2 PF13715.6 CBY24489.1 - 1.1e-07 31.8 0.0 0.0001 22.2 0.0 2.9 2 0 0 2 2 2 2 CarboxypepD_reg-like domain PEGA PF08308.11 CBY24489.1 - 0.00092 19.1 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 1 PEGA domain DUF2817 PF10994.8 CBY24489.1 - 0.041 13.3 0.8 6.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2817) Trypsin PF00089.26 CBY24490.1 - 7.6e-12 45.5 0.1 8.3e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Trypsin Peptidase_S6 PF02395.16 CBY24490.1 - 0.033 12.2 0.0 0.034 12.2 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin A1 protease ResIII PF04851.15 CBY24491.1 - 2.1e-25 89.7 0.0 7.2e-24 84.7 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBY24491.1 - 2.2e-23 82.7 0.5 2.6e-20 72.8 0.2 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 CBY24491.1 - 2.7e-20 72.8 0.1 6.9e-19 68.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CBY24491.1 - 1.5e-05 24.8 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 CBY24491.1 - 1.9e-05 24.1 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 CBY24491.1 - 0.00079 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 CBY24491.1 - 0.0056 15.5 0.1 0.016 14.0 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 CBY24491.1 - 0.0056 17.0 0.0 0.027 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBY24491.1 - 0.012 15.4 2.0 0.3 10.8 0.0 3.2 3 1 1 4 4 4 0 AAA domain AAA_19 PF13245.6 CBY24491.1 - 0.036 14.4 0.0 0.084 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 CBY24492.1 - 1.2e-102 344.2 0.1 5.4e-72 243.2 0.1 2.1 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease PF00324.21 CBY24492.1 - 1.1e-100 337.5 34.9 1.3e-100 337.3 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.10 CBY24492.1 - 8.4e-08 31.6 0.1 9.3e-07 28.3 0.1 2.3 2 0 0 2 2 2 1 Amino acid permease N-terminal FA_hydroxylase PF04116.13 CBY24492.1 - 0.83 10.0 4.6 1.1 9.7 1.7 2.7 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily Bestrophin PF01062.21 CBY24495.1 - 6.2e-98 327.8 6.8 7.4e-98 327.6 6.8 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel WD40 PF00400.32 CBY24496.1 - 1.9e-26 91.8 16.8 5.6e-05 23.8 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY24496.1 - 1.2e-09 38.3 2.0 0.003 17.8 0.3 4.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CBY24496.1 - 1.3e-08 35.2 0.1 2.3e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 CBY24496.1 - 0.00079 18.8 0.0 0.036 13.4 0.0 2.7 2 1 0 2 2 2 1 WD40-like domain DUF5069 PF16798.5 CBY24496.1 - 0.00096 19.4 0.1 0.0028 17.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5069) S8_pro-domain PF16470.5 CBY24497.1 - 0.14 13.0 3.0 0.45 11.3 0.8 2.8 1 1 1 2 2 2 0 Peptidase S8 pro-domain DUF4064 PF13273.6 CBY24498.1 - 0.022 15.0 3.3 0.022 15.0 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ASFV_J13L PF05568.11 CBY24498.1 - 0.99 9.1 0.0 0.99 9.1 0.0 2.1 2 1 0 2 2 2 0 African swine fever virus J13L protein Tetraspanin PF00335.20 CBY24498.1 - 2.8 7.6 19.0 26 4.4 19.0 2.0 1 1 0 1 1 1 0 Tetraspanin family DUF373 PF04123.13 CBY24498.1 - 7.3 5.9 10.0 10 5.4 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Ank_2 PF12796.7 CBY24499.1 - 4.6e-15 56.0 0.4 2e-09 37.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY24499.1 - 3.4e-07 30.4 0.2 1.4e-05 25.3 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY24499.1 - 1e-06 29.2 0.0 0.0014 19.2 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24499.1 - 0.00023 21.3 0.0 0.11 13.2 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 CBY24499.1 - 0.00026 21.3 0.3 0.27 11.8 0.0 3.6 3 1 0 3 3 3 1 Ankyrin repeat DUF5358 PF17311.2 CBY24499.1 - 0.023 14.7 1.8 0.05 13.6 1.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5358) DUF755 PF05501.11 CBY24499.1 - 0.09 13.1 7.5 0.16 12.2 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) E1_DerP2_DerF2 PF02221.15 CBY24500.1 - 0.00076 19.9 2.0 0.0027 18.1 2.0 1.9 1 1 0 1 1 1 1 ML domain Homeodomain PF00046.29 CBY24501.1 - 3.2e-19 68.5 6.2 7.9e-19 67.3 6.2 1.7 1 0 0 1 1 1 1 Homeodomain CUB PF00431.20 CBY24501.1 - 4.3e-05 23.8 0.1 0.00054 20.3 0.0 2.6 2 1 1 3 3 3 1 CUB domain Homeobox_KN PF05920.11 CBY24501.1 - 0.038 13.9 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain zf-C3HC4_3 PF13920.6 CBY24503.1 - 9.5e-11 41.4 8.9 1.2e-10 41.0 8.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY24503.1 - 1.3e-08 34.5 10.7 2e-08 34.0 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY24503.1 - 2e-08 34.0 13.1 7.9e-08 32.1 6.4 2.1 1 1 1 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY24503.1 - 2.9e-08 33.4 10.9 4.2e-08 32.9 10.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY24503.1 - 5e-07 29.6 7.8 9.1e-07 28.8 7.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY24503.1 - 7.3e-07 29.0 7.2 1.5e-06 27.9 7.4 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY24503.1 - 1e-06 29.0 10.0 1.4e-06 28.5 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBY24503.1 - 0.00074 19.8 9.2 0.0016 18.7 9.2 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY24503.1 - 0.00084 19.4 2.6 0.0011 18.9 2.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 CBY24503.1 - 0.0013 18.1 4.2 0.0014 18.0 4.2 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.6 CBY24503.1 - 0.012 15.4 2.2 0.017 15.0 2.2 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 CBY24503.1 - 0.035 13.7 5.2 0.049 13.3 5.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CBY24503.1 - 0.036 14.2 9.2 0.1 12.7 9.3 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING IBR PF01485.21 CBY24503.1 - 0.099 12.9 13.2 0.11 12.7 5.8 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 CBY24503.1 - 0.18 12.1 7.5 2.3 8.5 4.5 2.8 2 1 0 2 2 2 0 zinc-ribbon zf-RING_4 PF14570.6 CBY24503.1 - 0.47 10.3 14.1 3.3 7.6 14.0 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PolC_DP2 PF03833.13 CBY24503.1 - 0.54 8.1 4.6 0.53 8.1 4.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Zn_Tnp_IS1595 PF12760.7 CBY24503.1 - 1.4 8.9 10.9 1.7e+02 2.3 5.8 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-Nse PF11789.8 CBY24503.1 - 3.3 7.6 9.0 6.2 6.7 9.0 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_4 PF13894.6 CBY24503.1 - 4.9 8.3 9.7 7.9 7.6 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 CBY24503.1 - 5.6 7.0 13.7 3.7 7.6 0.1 3.4 2 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 CBY24503.1 - 5.7 7.0 9.8 67 3.6 9.8 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TRAPPC9-Trs120 PF08626.11 CBY24507.1 - 1.3e-39 135.4 2.8 5.3e-24 83.7 0.1 4.0 4 0 0 4 4 4 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 CBY24507.1 - 0.0061 16.8 2.3 0.62 10.4 0.3 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF1441 PF07278.11 CBY24507.1 - 0.066 13.1 0.1 15 5.5 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1441) Glycos_transf_2 PF00535.26 CBY24510.1 - 7.5e-28 97.5 0.0 1.3e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY24510.1 - 7.9e-15 55.2 1.6 5e-14 52.6 1.7 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CBY24510.1 - 0.00022 20.8 0.0 0.00051 19.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY24511.1 - 1.2e-25 90.3 0.0 1.9e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY24511.1 - 9.8e-07 29.1 0.2 2e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CBY24511.1 - 2.4e-06 27.1 0.3 5e-06 26.1 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY24511.1 - 0.0047 16.4 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CDtoxinA PF03498.14 CBY24511.1 - 0.35 10.4 1.3 3.8 7.1 0.3 2.3 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain Glyco_transf_64 PF09258.10 CBY24511.1 - 0.68 9.2 3.1 1.9 7.7 0.7 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain Macro PF01661.21 CBY24512.1 - 3.5e-41 140.0 0.1 5.4e-41 139.3 0.1 1.3 1 0 0 1 1 1 1 Macro domain DUF4202 PF13875.6 CBY24512.1 - 0.056 13.3 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) Syja_N PF02383.18 CBY24513.1 - 1.2e-53 182.5 0.1 1.9e-53 181.9 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CBY24513.1 - 9.6e-12 44.9 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ldl_recept_a PF00057.18 CBY24514.1 - 1.3e-16 60.5 67.4 2.1e-09 37.4 16.0 4.4 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 CBY24514.1 - 1.1e-05 25.8 18.3 1.2 9.6 0.1 9.3 11 0 0 11 11 11 2 Low-density lipoprotein receptor repeat class B SGL PF08450.12 CBY24514.1 - 0.00011 21.9 0.8 0.72 9.4 0.0 5.2 6 0 0 6 6 6 1 SMP-30/Gluconolactonase/LRE-like region FXa_inhibition PF14670.6 CBY24514.1 - 0.0025 18.1 7.6 0.0025 18.1 7.6 6.4 6 0 0 6 6 6 1 Coagulation Factor Xa inhibitory site DUF4394 PF14339.6 CBY24514.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) ATP-synt_C PF00137.21 CBY24515.1 - 2e-11 44.0 14.0 3.1e-11 43.5 14.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit C Surp PF01805.20 CBY24516.1 - 1.7e-19 69.5 0.1 3.6e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 CBY24516.1 - 3e-10 39.8 0.0 9.4e-10 38.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY24516.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Aminotran_1_2 PF00155.21 CBY24517.1 - 1.2e-06 28.0 0.0 1.3e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Guanylate_kin PF00625.21 CBY24518.1 - 8.4e-28 97.3 0.0 2e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Guanylate kinase SH3_1 PF00018.28 CBY24518.1 - 0.016 14.8 0.6 0.055 13.1 0.1 2.1 2 0 0 2 2 2 0 SH3 domain VGCC_beta4Aa_N PF12052.8 CBY24518.1 - 0.9 9.7 7.5 0.41 10.8 1.5 3.0 3 0 0 3 3 3 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal HMG_box PF00505.19 CBY24519.1 - 2.7e-28 98.2 4.1 4.4e-28 97.5 4.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY24519.1 - 2.4e-11 44.0 2.9 4.1e-11 43.3 2.9 1.4 1 0 0 1 1 1 1 HMG-box domain Ion_trans PF00520.31 CBY24520.1 - 3.3e-238 786.3 92.9 3.5e-68 229.5 10.7 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 CBY24520.1 - 3.3e-31 107.3 0.1 8.5e-31 106.0 0.1 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 CBY24520.1 - 1.5e-26 91.9 0.1 6.4e-26 89.9 0.1 2.2 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 CBY24520.1 - 1.8e-08 33.5 88.3 8.7e-06 24.7 10.8 9.5 7 3 3 10 10 10 7 Polycystin cation channel CAC1F_C PF16885.5 CBY24520.1 - 1.4e-05 25.0 6.8 0.031 13.9 0.1 2.9 3 0 0 3 3 3 2 Voltage-gated calcium channel subunit alpha, C-term DUF4773 PF15998.5 CBY24520.1 - 0.048 14.2 1.2 2.3 8.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4773) PAX PF00292.18 CBY24521.1 - 2.4e-62 208.4 0.2 2.4e-62 208.4 0.2 1.6 2 0 0 2 2 2 1 'Paired box' domain HTH_23 PF13384.6 CBY24521.1 - 7.4e-05 22.4 0.4 0.00014 21.6 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CBY24521.1 - 0.012 15.6 0.2 0.031 14.3 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_38 PF13936.6 CBY24521.1 - 0.038 13.8 2.5 0.081 12.7 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 CBY24521.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 CBY24521.1 - 0.088 12.7 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 MarR family ATP-gua_Ptrans PF00217.19 CBY24522.1 - 1.7e-57 194.4 0.0 2.2e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY24522.1 - 4.1e-23 81.5 0.0 7e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain KH_1 PF00013.29 CBY24525.1 - 5.1e-61 202.4 15.7 1.3e-17 63.3 0.4 4.3 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 CBY24525.1 - 1.3e-20 73.0 8.2 0.0001 22.1 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 CBY24525.1 - 7.2e-11 41.8 5.8 0.0063 16.4 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 CBY24525.1 - 3.6e-07 30.2 8.8 0.45 10.6 0.2 4.3 4 0 0 4 4 4 3 NusA-like KH domain MOEP19 PF16005.5 CBY24525.1 - 0.00081 19.3 0.1 6.4 6.9 0.0 4.1 4 0 0 4 4 4 1 KH-like RNA-binding domain ACP_syn_III_C PF08541.10 CBY24525.1 - 0.11 12.7 0.2 18 5.6 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Gar1 PF04410.14 CBY24526.1 - 8e-34 116.6 0.0 8e-34 116.6 0.0 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region RRM_1 PF00076.22 CBY24526.1 - 0.00025 20.8 0.2 0.0018 18.1 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.20 CBY24527.1 - 1.8e-63 211.0 0.0 1.5e-30 105.2 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 CBY24527.1 - 3e-11 43.7 0.8 0.0022 18.4 0.0 4.8 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY24527.1 - 2.2e-09 37.5 0.0 0.11 12.9 0.0 4.5 3 2 0 4 4 4 3 Thioredoxin-like OST3_OST6 PF04756.13 CBY24527.1 - 2.9e-08 33.4 0.0 0.0012 18.3 0.0 2.6 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CBY24527.1 - 1.3e-07 31.7 0.0 0.00052 20.2 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CBY24527.1 - 1.5e-05 24.9 0.1 0.016 15.1 0.0 3.0 4 0 0 4 4 4 2 AhpC/TSA family TraF PF13728.6 CBY24527.1 - 0.00049 20.0 0.0 0.31 10.8 0.0 3.3 3 1 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 CBY24527.1 - 0.0014 18.5 0.0 1.5 8.7 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CBY24527.1 - 0.0016 18.7 0.6 1.3 9.2 0.1 4.0 3 2 1 4 4 4 1 Thioredoxin Thioredoxin_3 PF13192.6 CBY24527.1 - 0.0031 17.5 0.0 3.9 7.6 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_5 PF13743.6 CBY24527.1 - 0.0037 17.0 0.0 9.6 5.8 0.0 4.2 3 2 2 5 5 5 1 Thioredoxin Thioredoxin_9 PF14595.6 CBY24527.1 - 0.042 13.6 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin HyaE PF07449.11 CBY24527.1 - 0.13 12.2 0.0 13 5.8 0.0 3.0 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE BAR PF03114.18 CBY24528.1 - 1.2e-34 120.1 4.4 1.5e-34 119.7 4.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 CBY24528.1 - 1.8e-14 53.3 0.4 2.9e-14 52.7 0.1 1.5 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.9 CBY24528.1 - 5.7e-14 51.9 1.8 7.6e-14 51.5 1.8 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_1 PF00018.28 CBY24528.1 - 1.3e-13 50.3 0.1 2.1e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY24528.1 - 6.1e-13 48.2 0.2 1.3e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain BAR_3 PF16746.5 CBY24528.1 - 8.5e-08 32.2 4.6 3.3e-07 30.3 4.6 1.8 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 CBY24528.1 - 0.0008 19.0 2.5 0.054 13.1 2.4 2.1 1 1 0 1 1 1 1 Arfaptin-like domain HAUS-augmin3 PF14932.6 CBY24528.1 - 0.054 13.1 5.1 0.053 13.1 4.0 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 BAR PF03114.18 CBY24529.1 - 7.2e-06 25.8 0.1 7.5e-06 25.8 0.1 1.0 1 0 0 1 1 1 1 BAR domain FCH PF00611.23 CBY24530.1 - 1.3e-11 44.6 5.9 1.9e-10 40.8 0.1 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 CBY24530.1 - 3.3e-11 42.9 0.0 5.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY24530.1 - 1.1e-08 34.5 0.0 2.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY24530.1 - 1.9e-06 27.5 0.0 3.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain 5_3_exonuc PF01367.20 CBY24530.1 - 0.43 11.2 2.5 1.3 9.7 2.5 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF4407 PF14362.6 CBY24530.1 - 3.5 6.9 6.2 10 5.4 6.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CUE PF02845.16 CBY24531.1 - 1.1e-07 31.4 0.0 2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain TRAM_LAG1_CLN8 PF03798.16 CBY24532.1 - 1.7e-14 54.0 6.4 1.7e-14 54.0 6.4 1.8 2 0 0 2 2 2 1 TLC domain Yip1 PF04893.17 CBY24532.1 - 1.1 9.0 7.0 8.2 6.1 2.4 2.6 2 1 0 2 2 2 0 Yip1 domain UQ_con PF00179.26 CBY24533.1 - 1.2e-18 67.1 0.0 1.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY24533.1 - 0.039 14.2 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain SprB PF13573.6 CBY24533.1 - 2.9 7.7 6.7 0.53 10.1 1.1 2.2 2 0 0 2 2 2 0 SprB repeat CLTH PF10607.9 CBY24534.1 - 3.8e-25 88.5 0.5 1.1e-24 87.0 0.5 1.8 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain TPR_MLP1_2 PF07926.12 CBY24534.1 - 0.0073 16.4 1.9 0.017 15.2 1.9 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein zf-UDP PF14569.6 CBY24534.1 - 0.041 14.0 2.0 0.074 13.2 0.3 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF4061 PF13270.6 CBY24534.1 - 0.093 13.1 2.3 0.26 11.6 2.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) zf-piccolo PF05715.13 CBY24534.1 - 0.14 12.3 3.0 0.32 11.2 0.7 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger SKA2 PF16740.5 CBY24534.1 - 0.44 10.4 6.2 0.18 11.6 3.2 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Snapin_Pallidin PF14712.6 CBY24534.1 - 0.44 11.0 7.0 7.2 7.1 4.8 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Occludin_ELL PF07303.13 CBY24534.1 - 0.48 11.2 6.5 0.2 12.4 3.5 2.0 2 0 0 2 2 2 0 Occludin homology domain GIT_CC PF16559.5 CBY24534.1 - 0.64 9.9 6.5 0.29 11.0 2.4 2.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Med9 PF07544.13 CBY24534.1 - 1.6 8.8 6.9 6.4 7.0 6.9 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_S24 PF00717.23 CBY24535.1 - 1.2e-09 38.0 0.1 1.9e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Fra10Ac1 PF09725.9 CBY24536.1 - 3.8e-47 159.5 3.2 3.8e-47 159.5 3.2 1.7 2 0 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 Prp31_C PF09785.9 CBY24536.1 - 0.00049 21.0 6.6 0.016 16.2 4.6 2.4 2 0 0 2 2 2 1 Prp31 C terminal domain Paramyxo_ncap PF00973.19 CBY24536.1 - 8 5.3 7.8 13 4.6 7.8 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TMEM189_B_dmain PF10520.9 CBY24537.1 - 1 9.5 5.3 0.91 9.6 4.1 1.5 1 1 0 1 1 1 0 B domain of TMEM189, localisation domain Tma16 PF11176.8 CBY24538.1 - 3.9e-28 98.2 5.4 4.5e-28 98.0 5.4 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 UCH PF00443.29 CBY24538.1 - 0.0063 16.0 0.6 0.0063 16.0 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3510 PF12022.8 CBY24538.1 - 0.041 14.3 0.3 0.066 13.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Topoisom_I_N PF02919.15 CBY24538.1 - 0.11 11.9 1.6 0.098 12.1 0.5 1.4 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Pkinase PF00069.25 CBY24539.1 - 2.6e-28 99.1 0.0 6.5e-28 97.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24539.1 - 3.2e-26 92.2 0.1 2.3e-14 53.3 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY24539.1 - 0.0087 14.9 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Activin_recp PF01064.23 CBY24539.1 - 0.012 16.7 12.1 0.038 15.1 12.1 1.9 1 0 0 1 1 1 0 Activin types I and II receptor domain BAMBI PF06211.12 CBY24539.1 - 1.8 8.8 10.6 6.2 7.1 10.6 1.9 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain DUF1682 PF07946.14 CBY24540.1 - 1.8e-65 221.3 1.9 2.3e-65 220.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) COX16 PF14138.6 CBY24540.1 - 7.1 7.2 8.1 1.6e+02 2.9 9.8 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF3585 PF12130.8 CBY24541.1 - 4.5e-17 62.5 13.0 4.5e-17 62.5 13.0 2.0 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 CBY24541.1 - 4.8e-13 49.2 0.5 3.2e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBY24541.1 - 0.00055 19.7 0.0 0.002 17.9 0.0 2.0 1 1 0 1 1 1 1 CAMSAP CH domain Sedlin_N PF04628.13 CBY24542.1 - 5e-35 120.5 0.0 5.5e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CBY24542.1 - 2.6e-05 24.2 0.0 3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Adap_comp_sub PF00928.21 CBY24543.1 - 1.2e-81 274.0 0.0 1.6e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBY24543.1 - 1.7e-07 31.3 0.5 2.9e-07 30.5 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Prp18 PF02840.15 CBY24544.1 - 2.1e-53 180.2 0.1 4.9e-53 179.0 0.1 1.6 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 CBY24544.1 - 1e-11 44.2 0.6 2e-11 43.2 0.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like YL1 PF05764.13 CBY24546.1 - 1.7 8.7 7.4 1.8 8.6 7.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Citrate_synt PF00285.21 CBY24547.1 - 2.2e-102 342.8 0.0 2.6e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 CBY24547.1 - 0.024 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Eclosion hormone Rhomboid PF01694.22 CBY24548.1 - 8.2e-16 58.4 3.6 1.6e-15 57.4 3.6 1.3 1 0 0 1 1 1 1 Rhomboid family Hairpins PF04877.12 CBY24549.1 - 0.012 15.3 1.5 0.03 14.0 1.5 1.7 1 1 0 1 1 1 0 HrpZ Ag332 PF04671.12 CBY24549.1 - 0.59 10.1 4.1 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Erythrocyte membrane-associated giant protein antigen 332 PWWP PF00855.17 CBY24550.1 - 0.0001 22.7 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 PWWP domain TTL PF03133.15 CBY24551.1 - 6.5e-45 153.5 0.2 1e-44 152.9 0.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY24551.1 - 2.8e-06 26.8 0.0 7.8e-05 22.0 0.0 2.4 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY24551.1 - 0.0049 16.1 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 CBY24551.1 - 0.069 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF4513 PF14983.6 CBY24552.1 - 1.3e-05 25.3 0.2 1.8e-05 24.9 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4513) ADK PF00406.22 CBY24553.1 - 4.7e-11 43.0 0.0 1.4e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBY24553.1 - 0.041 14.3 0.1 0.14 12.6 0.1 1.9 1 0 0 1 1 1 0 AAA domain FAM176 PF14851.6 CBY24553.1 - 0.46 10.1 4.3 1.4 8.5 4.3 1.8 1 0 0 1 1 1 0 FAM176 family Trefoil PF00088.18 CBY24554.1 - 2.9e-13 49.5 27.2 2.8e-07 30.3 2.4 3.9 4 0 0 4 4 4 3 Trefoil (P-type) domain Radial_spoke_3 PF06098.11 CBY24556.1 - 6.6e-116 386.6 16.2 8.7e-116 386.2 16.2 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 LMBR1 PF04791.16 CBY24556.1 - 2.6 6.9 4.4 3.4 6.5 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4239 PF14023.6 CBY24556.1 - 3.4 7.3 4.5 14 5.4 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Macoilin PF09726.9 CBY24556.1 - 6.9 5.1 15.5 0.59 8.6 10.2 1.7 2 0 0 2 2 2 0 Macoilin family Zip PF02535.22 CBY24557.1 - 0.68 9.1 2.9 1.4 8.0 2.9 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter TMEM234 PF10639.9 CBY24558.1 - 2.4e-21 75.9 1.6 2.8e-21 75.7 1.6 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 SPOC PF07744.13 CBY24559.1 - 8.6e-20 71.2 0.0 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain Spore_YhcN_YlaJ PF09580.10 CBY24559.1 - 0.00056 20.0 0.0 0.027 14.6 0.0 2.6 1 1 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Cyt-b5 PF00173.28 CBY24561.1 - 2.8e-26 91.4 0.0 4e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HC2 PF13490.6 CBY24561.1 - 0.088 13.1 0.7 0.17 12.2 0.7 1.4 1 0 0 1 1 1 0 Putative zinc-finger Sulfotransfer_2 PF03567.14 CBY24563.1 - 9.1e-23 81.4 0.4 9.1e-23 81.4 0.4 1.6 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY24563.1 - 0.0017 17.9 0.3 0.016 14.7 0.3 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Ac76 PF05814.11 CBY24563.1 - 0.035 14.1 0.4 0.084 12.9 0.4 1.6 1 0 0 1 1 1 0 Orf76 (Ac76) MRP-63 PF14978.6 CBY24563.1 - 0.091 13.4 0.7 1.3 9.7 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosome protein 63 Chromo PF00385.24 CBY24564.1 - 5.6e-30 103.0 4.3 4.4e-11 42.5 0.1 3.8 3 0 0 3 3 3 3 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CBY24564.1 - 0.0016 18.2 4.8 0.016 15.1 0.1 2.9 3 0 0 3 3 3 2 RNA binding activity-knot of a chromodomain DUF1918 PF08940.11 CBY24564.1 - 0.062 12.9 0.8 6.2 6.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) DDHD PF02862.17 CBY24564.1 - 3.8 7.6 13.7 0.44 10.7 5.7 2.3 2 1 0 2 2 2 0 DDHD domain PQ-loop PF04193.14 CBY24565.1 - 1.5e-26 91.9 14.7 1.1e-14 53.9 4.7 3.1 3 0 0 3 3 3 2 PQ loop repeat Collagen PF01391.18 CBY24566.1 - 0.029 14.1 12.3 0.051 13.3 12.3 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Trypsin PF00089.26 CBY24567.1 - 9.9e-68 228.3 4.0 2.7e-34 118.9 0.1 2.1 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.11 CBY24567.1 - 8.8e-10 39.0 0.6 4.3e-06 27.1 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Lectin_C PF00059.21 CBY24568.1 - 1.7e-46 157.4 23.1 3.4e-13 50.3 3.7 4.3 4 0 0 4 4 4 4 Lectin C-type domain UL45 PF05473.12 CBY24568.1 - 0.039 13.6 9.4 7 6.2 0.1 4.0 4 0 0 4 4 4 0 UL45 protein, carbohydrate-binding C-type lectin-like Trefoil PF00088.18 CBY24568.1 - 0.12 12.3 9.0 0.13 12.2 6.6 2.4 2 0 0 2 2 2 0 Trefoil (P-type) domain DUF3440 PF11922.8 CBY24569.1 - 0.0055 16.4 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3440) RRM_1 PF00076.22 CBY24570.1 - 9.3e-20 70.2 0.1 1.7e-14 53.4 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY24570.1 - 0.001 18.9 0.0 0.0037 17.1 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CBY24570.1 - 0.0012 18.8 0.1 0.33 11.0 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.6 CBY24570.1 - 0.048 13.3 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_8 PF13855.6 CBY24571.1 - 7.1e-21 73.7 30.4 4.3e-10 39.2 3.7 4.4 4 1 2 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 CBY24571.1 - 7e-07 29.5 23.1 0.00041 20.7 3.5 4.3 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY24571.1 - 0.00095 18.7 0.6 0.00095 18.7 0.6 2.2 2 1 1 3 3 3 1 Leucine-rich repeat LRR_5 PF13306.6 CBY24571.1 - 0.0077 16.2 0.5 0.017 15.0 0.5 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBY24571.1 - 0.18 12.5 0.2 0.18 12.5 0.2 6.4 5 2 1 6 6 6 0 Leucine Rich Repeat Kazal_1 PF00050.21 CBY24572.1 - 9.3e-08 32.0 14.9 2.5e-06 27.4 4.2 3.2 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CBY24572.1 - 4.7e-06 26.6 17.3 0.0014 18.7 6.9 3.3 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Sulfotransfer_1 PF00685.27 CBY24573.1 - 4.5e-13 49.3 0.0 2.4e-12 46.9 0.0 2.2 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY24573.1 - 5.2e-12 46.6 0.0 0.0034 17.8 0.0 3.5 1 1 2 3 3 3 3 Sulfotransferase family PMP22_Claudin PF00822.20 CBY24574.1 - 3.6e-07 30.2 6.1 4.7e-07 29.8 6.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family AA_permease_2 PF13520.6 CBY24574.1 - 0.0035 16.2 2.2 0.0054 15.6 2.2 1.4 1 1 0 1 1 1 1 Amino acid permease MT-A70 PF05063.14 CBY24576.1 - 1.7e-26 93.2 0.1 2.8e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 MT-A70 MethyltransfD12 PF02086.15 CBY24576.1 - 0.02 14.6 0.2 0.029 14.0 0.2 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.15 CBY24576.1 - 0.03 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Arm-DNA-bind_5 PF17293.2 CBY24576.1 - 0.28 11.6 2.6 1.1 9.7 0.1 2.9 2 1 0 2 2 2 0 Arm DNA-binding domain HEAT_2 PF13646.6 CBY24577.1 - 3.9e-25 88.0 1.1 2.3e-14 53.5 0.1 3.0 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 CBY24577.1 - 4.4e-18 64.1 0.2 0.022 15.4 0.0 6.9 6 1 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.22 CBY24577.1 - 6.4e-07 29.1 0.4 0.11 12.8 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat KNOX2 PF03791.13 CBY24577.1 - 0.009 15.5 0.0 0.35 10.4 0.0 2.7 2 0 0 2 2 2 1 KNOX2 domain HEAT_EZ PF13513.6 CBY24577.1 - 0.029 14.9 0.3 46 4.6 0.0 4.0 5 1 0 5 5 5 0 HEAT-like repeat DUF3385 PF11865.8 CBY24577.1 - 0.097 12.6 0.0 4 7.3 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) Dpy-30 PF05186.13 CBY24578.1 - 5.9e-17 61.1 0.1 1.3e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 CBY24578.1 - 2.3e-12 47.3 0.2 5.2e-08 33.1 0.1 2.5 2 0 0 2 2 2 2 Adenylate kinase AAA_18 PF13238.6 CBY24578.1 - 5.2e-09 36.7 0.0 1.8e-08 35.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.6 CBY24578.1 - 3.9e-07 30.6 4.7 0.00026 21.4 0.1 3.2 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 CBY24578.1 - 5.1e-07 30.2 0.2 1.2e-05 25.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CBY24578.1 - 0.00015 22.2 0.0 0.00042 20.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CBY24578.1 - 0.0011 19.2 0.0 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 CBY24578.1 - 0.0018 18.6 1.7 0.0018 18.6 1.7 2.6 3 1 0 3 3 2 1 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 CBY24578.1 - 0.0037 17.5 0.2 0.042 14.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 CBY24578.1 - 0.0076 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CBY24578.1 - 0.009 16.2 0.1 0.048 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBY24578.1 - 0.0098 15.9 0.0 0.03 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBY24578.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CBY24578.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 CBY24578.1 - 0.024 14.1 1.9 0.075 12.5 0.0 2.5 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CBY24578.1 - 0.024 13.9 2.7 0.38 10.0 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 CBY24578.1 - 0.047 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBY24578.1 - 0.082 12.8 0.2 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CBY24578.1 - 0.087 13.2 0.0 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 CBY24578.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.22 CBY24578.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.6 3 0 0 3 3 3 0 Shikimate kinase 6PF2K PF01591.18 CBY24578.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF5645 PF18713.1 CBY24579.1 - 0.022 15.1 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) MutL_C PF08676.11 CBY24580.1 - 1.8e-22 79.7 0.0 3.4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CBY24580.1 - 2e-22 79.1 0.1 5.4e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CBY24580.1 - 6.3e-15 55.2 0.8 1.9e-14 53.6 0.8 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBY24580.1 - 1.7e-07 31.7 0.2 7.7e-07 29.6 0.1 2.2 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Arc PF03869.14 CBY24580.1 - 0.098 12.5 0.0 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 Arc-like DNA binding domain RRM_1 PF00076.22 CBY24581.1 - 9.4e-40 134.3 0.0 5.1e-17 61.5 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF667 PF05018.13 CBY24581.1 - 6.3e-27 94.5 0.0 5.8e-17 62.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF667) RRM_occluded PF16842.5 CBY24581.1 - 0.0026 17.6 0.0 0.33 10.8 0.0 3.7 4 0 0 4 4 4 1 Occluded RNA-recognition motif WD40 PF00400.32 CBY24581.1 - 0.0069 17.2 6.7 35 5.5 0.0 6.4 7 0 0 7 7 7 1 WD domain, G-beta repeat Limkain-b1 PF11608.8 CBY24581.1 - 0.0097 16.0 0.2 0.84 9.8 0.1 3.3 3 0 0 3 3 3 1 Limkain b1 RRM_1 PF00076.22 CBY24582.1 - 4.2e-31 106.6 0.1 3e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY24582.1 - 0.00014 21.5 0.0 0.018 14.7 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBY24582.1 - 0.00018 21.5 0.1 0.018 15.1 0.0 3.2 2 2 0 2 2 2 1 Limkain b1 RRM_7 PF16367.5 CBY24582.1 - 0.082 13.0 0.2 0.34 11.0 0.0 2.2 2 2 0 2 2 2 0 RNA recognition motif IBR PF01485.21 CBY24583.1 - 7.5e-20 70.9 26.1 9.7e-14 51.3 10.3 4.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Sec23_trunk PF04811.15 CBY24584.1 - 2e-57 194.5 0.0 3.3e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CBY24584.1 - 3.7e-18 66.1 0.0 6.7e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CBY24584.1 - 5.1e-15 55.1 0.6 1.5e-14 53.6 0.6 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CBY24584.1 - 2.8e-14 52.9 4.8 5.7e-14 51.9 4.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 CBY24584.1 - 0.018 14.5 0.7 0.044 13.2 0.7 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MFS_1 PF07690.16 CBY24585.1 - 7.6e-26 90.9 19.1 7.6e-26 90.9 19.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Ycf70 PF17382.2 CBY24585.1 - 1.7 9.1 5.4 4 7.9 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized Ycf70-like Lactamase_B_6 PF16661.5 CBY24586.1 - 1.7e-09 37.4 0.1 3.7e-09 36.3 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 CBY24586.1 - 1.3e-06 28.7 0.0 3.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 CBY24586.1 - 1.9e-05 24.0 0.1 3.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Helicase_C PF00271.31 CBY24587.1 - 9.3e-19 67.8 0.4 4.2e-18 65.7 0.1 2.2 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY24587.1 - 2.2e-15 56.9 0.9 9.4e-15 54.8 0.9 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBY24587.1 - 9.8e-05 22.4 0.1 0.00023 21.2 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBY24587.1 - 0.00067 19.4 0.1 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain SecA_DEAD PF07517.14 CBY24587.1 - 0.00084 18.7 1.3 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_22 PF13401.6 CBY24587.1 - 0.0011 19.2 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 CBY24587.1 - 0.013 14.9 0.4 0.19 11.1 0.4 2.3 1 1 0 1 1 1 0 PhoH-like protein Defensin_2 PF01097.18 CBY24588.1 - 0.0025 17.7 0.1 0.0067 16.3 0.1 1.7 1 0 0 1 1 1 1 Arthropod defensin Homeodomain PF00046.29 CBY24589.1 - 7.3e-22 77.0 4.7 1.2e-21 76.3 4.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY24589.1 - 2.1e-05 24.4 1.8 0.00019 21.3 1.8 2.4 1 1 0 1 1 1 1 Homeobox KN domain DUF4207 PF13904.6 CBY24589.1 - 0.027 14.2 0.4 0.037 13.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) AC_N PF16214.5 CBY24589.1 - 0.28 10.3 1.3 0.34 10.0 1.3 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Homeodomain PF00046.29 CBY24590.1 - 9.6e-22 76.6 5.5 1.5e-21 76.0 5.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY24590.1 - 0.0002 21.2 4.5 0.0026 17.6 4.5 2.4 1 1 0 1 1 1 1 Homeobox KN domain Ank_5 PF13857.6 CBY24591.1 - 0.00026 21.2 0.0 0.00036 20.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY24591.1 - 0.0033 18.0 0.0 0.007 16.9 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY24591.1 - 0.057 13.9 0.0 0.64 10.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 CBY24591.1 - 0.16 12.7 0.0 1.6 9.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Arm PF00514.23 CBY24592.1 - 0.094 12.8 11.6 1.9 8.6 0.0 6.1 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 CBY24592.1 - 0.13 12.4 0.5 0.84 9.8 0.1 2.5 2 1 0 2 2 2 0 V-ATPase subunit H zf-met PF12874.7 CBY24593.1 - 6.1e-11 42.3 11.1 1.6e-06 28.3 2.0 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY24593.1 - 3.5e-10 39.9 11.8 3.4e-06 27.2 2.5 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY24593.1 - 8.8e-05 22.8 8.6 0.00087 19.6 0.6 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CBY24593.1 - 0.0001 22.7 6.4 0.0004 20.8 1.6 2.2 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-U1 PF06220.12 CBY24593.1 - 0.00054 19.7 4.6 0.0049 16.6 0.1 2.4 2 1 0 2 2 2 1 U1 zinc finger AKAP95 PF04988.12 CBY24593.1 - 0.015 15.6 5.7 0.16 12.2 0.4 2.1 1 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 CBY24593.1 - 0.029 15.2 6.5 2.3 9.3 1.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4093 PF13331.6 CBY24593.1 - 0.078 13.4 0.8 0.36 11.3 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4093) Rpr2 PF04032.16 CBY24593.1 - 0.11 12.9 5.0 0.23 11.8 2.4 2.0 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.14 CBY24593.1 - 0.12 12.8 1.4 1 9.7 1.7 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme CPP1-like PF11833.8 CBY24594.1 - 0.00018 21.2 2.2 0.00032 20.4 2.2 1.4 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4064 PF13273.6 CBY24594.1 - 0.0011 19.2 1.8 0.33 11.2 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) YbjM PF11045.8 CBY24594.1 - 0.02 15.0 0.1 0.53 10.5 0.1 2.1 2 0 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae DsbD_2 PF13386.6 CBY24594.1 - 0.021 14.8 0.5 0.028 14.3 0.5 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF1980 PF09323.10 CBY24594.1 - 0.099 12.5 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Kelch_1 PF01344.25 CBY24595.1 - 3.4e-23 81.0 1.0 1e-08 34.6 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CBY24595.1 - 9.9e-21 73.3 2.6 1.5e-05 25.1 0.0 6.0 3 2 3 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CBY24595.1 - 3.3e-14 52.2 0.1 0.00062 19.6 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CBY24595.1 - 2.8e-11 43.2 5.1 0.00099 19.1 0.0 5.9 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY24595.1 - 1e-08 35.2 2.1 0.047 14.0 0.0 6.4 6 2 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY24595.1 - 1.1e-06 28.4 1.8 3.8 7.6 0.0 5.6 6 0 0 6 6 6 2 Kelch motif DUF2963 PF11178.8 CBY24595.1 - 0.02 14.6 0.1 0.079 12.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) DAP PF15228.6 CBY24597.1 - 1e-11 45.9 4.5 1.5e-11 45.3 4.5 1.3 1 0 0 1 1 1 1 Death-associated protein Galactosyl_T PF01762.21 CBY24598.1 - 1.1e-20 74.4 0.2 1.7e-20 73.6 0.2 1.3 1 0 0 1 1 1 1 Galactosyltransferase MBOAT PF03062.19 CBY24599.1 - 8.8e-34 117.4 24.9 1.1e-33 117.0 24.9 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CBY24599.1 - 0.0015 18.8 3.5 0.0015 18.8 3.5 2.8 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family adh_short_C2 PF13561.6 CBY24600.1 - 6.4e-58 196.1 0.9 7.5e-58 195.8 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY24600.1 - 5.9e-45 153.1 0.5 8.3e-45 152.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CBY24600.1 - 1.6e-05 24.5 0.1 5.5e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 CBY24600.1 - 0.034 14.2 0.2 0.054 13.6 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Corona_NS2A PF05213.12 CBY24600.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NS2A protein 3HCDH_N PF02737.18 CBY24600.1 - 0.14 12.0 0.5 0.39 10.6 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fibrinogen_BP PF08017.11 CBY24601.1 - 0.32 9.4 0.3 0.35 9.3 0.3 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein LRR_6 PF13516.6 CBY24602.1 - 2e-15 55.4 14.1 0.00048 20.0 0.4 8.8 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 CBY24602.1 - 6.5e-07 29.6 7.7 1.3 9.6 0.0 5.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY24602.1 - 0.022 14.5 11.1 0.39 10.5 0.2 5.5 4 2 0 5 5 5 0 Leucine rich repeat nos_propeller PF18764.1 CBY24602.1 - 0.029 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat LRR_1 PF00560.33 CBY24602.1 - 0.077 13.6 9.8 11 7.0 0.5 6.0 6 2 0 6 6 6 0 Leucine Rich Repeat COS PF18568.1 CBY24602.1 - 0.083 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain zf-C3HC4_3 PF13920.6 CBY24603.1 - 3.6e-11 42.7 18.0 6.5e-11 41.9 18.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.30 CBY24603.1 - 7.9e-06 26.2 0.1 2.5e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY24603.1 - 0.00068 19.7 0.1 0.0021 18.2 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Prok-RING_4 PF14447.6 CBY24603.1 - 0.021 14.7 19.5 0.044 13.7 19.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY24603.1 - 0.074 13.4 20.6 0.15 12.4 20.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 CBY24603.1 - 0.23 11.4 17.5 0.52 10.3 17.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_transf_43 PF03360.16 CBY24603.1 - 8.5 6.1 7.0 0.36 10.6 0.4 2.0 2 1 0 2 2 2 0 Glycosyltransferase family 43 LRR_8 PF13855.6 CBY24604.1 - 4.4e-08 32.8 7.0 4.4e-08 32.8 7.0 2.0 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CBY24604.1 - 5.6e-05 23.4 4.0 5.6e-05 23.4 4.0 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY24604.1 - 0.0018 18.5 11.3 0.49 11.1 0.2 4.2 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY24604.1 - 0.027 14.5 15.9 0.47 10.6 0.5 4.5 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 CBY24605.1 - 1.1e-09 38.4 25.7 1.9e-07 31.3 3.3 4.7 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY24605.1 - 6.5e-08 32.2 17.2 7.9e-06 25.6 5.0 3.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CBY24605.1 - 0.0062 16.9 21.1 0.023 15.2 0.6 5.7 5 1 0 5 5 5 1 Leucine Rich Repeat PAC3 PF10178.9 CBY24606.1 - 1.1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 tRNA-synt_1c PF00749.21 CBY24607.1 - 7.2e-107 356.9 0.0 1.1e-106 356.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBY24607.1 - 2.9e-35 121.7 0.2 6.9e-35 120.5 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CBY24607.1 - 9.7e-23 80.9 4.0 3e-22 79.4 4.0 1.9 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 tRNA_synt_1c_R1 PF04558.15 CBY24607.1 - 1.6e-20 73.8 4.0 3.2e-17 63.0 1.0 2.9 2 1 1 3 3 3 2 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 LAGLIDADG_1 PF00961.19 CBY24607.1 - 0.021 15.8 0.4 0.069 14.1 0.4 1.8 1 0 0 1 1 1 0 LAGLIDADG endonuclease Ras PF00071.22 CBY24610.1 - 1.8e-57 193.5 0.0 2.1e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY24610.1 - 9.7e-32 109.7 0.0 1.3e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY24610.1 - 1.2e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY24610.1 - 1.7e-05 24.9 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY24610.1 - 0.00035 20.5 0.1 0.68 9.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CBY24610.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY24610.1 - 0.01 15.2 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 CBY24610.1 - 0.099 12.0 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 CBY24610.1 - 0.13 12.6 0.0 0.63 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 CBY24610.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain CCDC-167 PF15188.6 CBY24611.1 - 0.013 15.9 5.6 0.016 15.5 5.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 KASH_CCD PF14662.6 CBY24611.1 - 0.022 14.6 6.4 0.024 14.5 6.4 1.0 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Phage_GP20 PF06810.11 CBY24611.1 - 0.045 13.6 7.4 0.051 13.4 7.4 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Tho2 PF11262.8 CBY24611.1 - 0.096 11.9 5.3 0.11 11.7 5.3 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMPIT PF07851.13 CBY24611.1 - 2 7.6 5.0 2.2 7.5 5.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran PF00005.27 CBY24612.1 - 3.8e-20 72.8 0.0 8.7e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane_2 PF06472.15 CBY24612.1 - 3.5e-18 66.0 0.2 5e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_21 PF13304.6 CBY24612.1 - 1.1e-07 31.9 0.5 2.2e-07 31.0 0.2 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBY24612.1 - 0.00046 19.9 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 CBY24612.1 - 0.0012 18.3 0.3 0.0086 15.5 0.1 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBY24612.1 - 0.0033 18.0 2.2 0.0034 17.9 0.2 2.0 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 CBY24612.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Lon_2 PF13337.6 CBY24612.1 - 0.014 14.0 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease RsgA_GTPase PF03193.16 CBY24612.1 - 0.016 15.1 0.0 0.091 12.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 CBY24612.1 - 0.016 15.5 0.0 0.048 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 CBY24612.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 CBY24612.1 - 0.038 13.3 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 CBY24612.1 - 0.053 12.6 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 CBY24612.1 - 0.064 13.0 0.0 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 CBY24612.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 CBY24612.1 - 0.14 11.7 0.0 0.61 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBY24612.1 - 0.19 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sulfatase PF00884.23 CBY24613.1 - 1.1e-48 166.2 0.1 1.4e-48 165.9 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY24613.1 - 0.00018 21.2 1.5 0.00077 19.2 1.5 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 CBY24613.1 - 0.0033 17.3 0.1 0.03 14.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function bZIP_1 PF00170.21 CBY24614.1 - 3.8e-18 65.3 12.5 3.8e-18 65.3 12.5 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CBY24614.1 - 1.8e-06 27.9 12.8 1.8e-06 27.9 12.8 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY24614.1 - 0.0076 16.8 2.3 0.0076 16.8 2.3 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Rh5 PF18515.1 CBY24614.1 - 0.19 11.0 1.4 0.28 10.4 1.4 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain Reprolysin_2 PF13574.6 CBY24616.1 - 4.9e-24 85.3 0.5 9.6e-24 84.4 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CBY24616.1 - 1.3e-21 77.6 0.1 3.2e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 CBY24616.1 - 2.6e-11 44.2 22.3 2.6e-11 44.2 22.3 3.8 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 CBY24616.1 - 2.4e-09 37.8 0.4 1.5e-08 35.2 0.4 2.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY24616.1 - 0.014 15.0 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like P21-Arc PF04062.14 CBY24617.1 - 6.1e-63 212.0 0.0 6.8e-63 211.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit SipA PF09052.10 CBY24617.1 - 0.056 13.0 0.0 0.091 12.4 0.0 1.3 1 1 0 1 1 1 0 SipA N-terminal domain Docking PF08990.11 CBY24617.1 - 0.16 11.6 0.3 0.29 10.8 0.3 1.3 1 0 0 1 1 1 0 Erythronolide synthase docking bZIP_1 PF00170.21 CBY24618.1 - 1.2e-18 66.9 12.3 1.7e-18 66.5 12.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY24618.1 - 2.1e-07 30.9 12.7 3e-07 30.4 12.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY24618.1 - 2.8e-05 24.6 6.5 4.1e-05 24.0 6.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 CBY24618.1 - 0.0034 16.8 0.5 0.0042 16.5 0.5 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Nnf1 PF03980.14 CBY24618.1 - 0.0099 16.3 0.7 0.014 15.7 0.7 1.3 1 0 0 1 1 1 1 Nnf1 TMCO5 PF14992.6 CBY24618.1 - 0.021 14.4 0.3 0.025 14.2 0.3 1.1 1 0 0 1 1 1 0 TMCO5 family HALZ PF02183.18 CBY24618.1 - 0.077 13.2 1.9 0.13 12.5 1.9 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3128 PF11326.8 CBY24618.1 - 0.8 10.1 5.7 1.4 9.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) GLE1 PF07817.13 CBY24619.1 - 1.1e-27 96.9 0.0 9.1e-19 67.6 0.0 2.4 1 1 1 2 2 2 2 GLE1-like protein KptA_kDCL PF18176.1 CBY24619.1 - 0.0012 18.7 0.2 0.44 10.4 0.0 2.3 2 0 0 2 2 2 2 KptA in kinetoplastid DICER domain DUF4407 PF14362.6 CBY24619.1 - 0.0073 15.7 8.5 0.012 15.0 8.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) XRN_M PF17846.1 CBY24619.1 - 3 6.7 7.9 4.4 6.2 7.9 1.3 1 0 0 1 1 1 0 Xrn1 helical domain YlqD PF11068.8 CBY24619.1 - 4.3 7.7 10.4 1.8 8.9 7.7 1.7 2 0 0 2 2 2 0 YlqD protein MFS_1 PF07690.16 CBY24621.1 - 6.9e-34 117.3 30.7 1.5e-32 112.9 30.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY24621.1 - 6.2e-11 41.8 18.7 5.5e-09 35.4 18.7 2.9 1 1 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 CBY24621.1 - 0.0027 16.6 6.6 0.0027 16.6 6.6 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter Snf7 PF03357.21 CBY24622.1 - 2.7e-31 108.5 9.6 3e-31 108.3 9.6 1.0 1 0 0 1 1 1 1 Snf7 Trns_repr_metal PF02583.17 CBY24622.1 - 0.0041 17.5 2.7 0.0084 16.5 2.7 1.5 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor Raco_middle PF17651.1 CBY24622.1 - 0.034 13.8 1.3 0.065 12.9 0.9 1.5 1 1 1 2 2 2 0 RACo middle region GreA_GreB_N PF03449.15 CBY24622.1 - 0.058 13.6 2.3 9.5 6.5 0.0 3.2 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal PhoU PF01895.19 CBY24622.1 - 0.085 13.3 4.7 0.36 11.3 0.4 2.2 1 1 1 2 2 2 0 PhoU domain AHD PF17793.1 CBY24622.1 - 0.17 11.7 2.7 4.4 7.2 1.4 2.3 1 1 1 2 2 2 0 ANC1 homology domain (AHD) TssO PF17561.2 CBY24622.1 - 1 9.4 5.6 1.5 8.9 5.6 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssO L31 PF09784.9 CBY24622.1 - 3 8.3 5.8 4.2 7.8 2.2 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 Nop25 PF09805.9 CBY24622.1 - 5.9 7.4 8.1 12 6.4 7.9 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) Autophagy_N PF03986.13 CBY24623.1 - 9.5e-47 158.4 0.2 1.5e-46 157.7 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CBY24623.1 - 8.9e-18 64.6 0.2 2e-17 63.5 0.2 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CBY24623.1 - 8.4e-14 50.8 1.5 1.5e-13 50.0 1.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SDA1 PF05285.12 CBY24623.1 - 1.6 8.0 5.1 1.1 8.6 3.4 1.6 2 0 0 2 2 2 0 SDA1 COPI_C PF06957.11 CBY24623.1 - 2 7.1 4.4 2.9 6.6 4.4 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Dus PF01207.17 CBY24624.1 - 2.9e-54 184.3 0.0 4.6e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 CBY24624.1 - 0.0032 17.3 5.7 0.0032 17.3 5.7 3.7 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Med2 PF11214.8 CBY24624.1 - 0.35 11.0 3.5 0.78 9.9 3.5 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 zf_CCCH_4 PF18345.1 CBY24624.1 - 0.77 9.9 15.4 0.19 11.8 4.7 3.7 3 0 0 3 3 3 0 Zinc finger domain CEP19 PF14933.6 CBY24625.1 - 7e-21 75.2 23.4 7e-14 52.5 8.7 3.1 1 1 1 2 2 2 2 CEP19-like protein RE_NgoFVII PF09565.10 CBY24625.1 - 0.97 8.7 11.2 1 8.6 10.5 1.3 1 1 0 1 1 1 0 NgoFVII restriction endonuclease DUF3456 PF11938.8 CBY24626.1 - 7.3e-35 120.8 1.6 9e-35 120.5 1.6 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Sec1 PF00995.23 CBY24627.1 - 5.4e-103 346.2 2.5 6.1e-103 346.0 2.5 1.0 1 0 0 1 1 1 1 Sec1 family UPF0449 PF15136.6 CBY24627.1 - 0.097 13.1 0.8 0.58 10.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF5633 PF18656.1 CBY24628.1 - 0.18 11.7 0.2 0.18 11.7 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5633) SelB-wing_1 PF09105.10 CBY24629.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Tetraspanin PF00335.20 CBY24630.1 - 1.2e-08 35.0 0.3 1.3e-08 34.8 0.3 1.0 1 0 0 1 1 1 1 Tetraspanin family PLAT PF01477.23 CBY24631.1 - 1.2e-83 277.4 34.5 6.7e-20 71.8 0.2 7.1 7 0 0 7 7 7 7 PLAT/LH2 domain ATS3 PF06232.11 CBY24631.1 - 2.3e-14 53.4 1.4 0.16 11.9 0.0 7.4 5 2 2 7 7 7 5 Embryo-specific protein 3, (ATS3) TRAP-gamma PF07074.12 CBY24632.1 - 2.7e-65 219.1 1.3 3.1e-65 218.9 1.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Ribonucleas_3_3 PF14622.6 CBY24632.1 - 0.023 14.8 0.1 0.035 14.3 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like LrgB PF04172.16 CBY24632.1 - 0.12 11.9 2.4 0.079 12.5 0.3 1.7 2 0 0 2 2 2 0 LrgB-like family MH2 PF03166.14 CBY24633.1 - 1.1e-13 51.8 1.4 2.5e-13 50.7 0.1 2.1 2 1 0 2 2 2 1 MH2 domain MH1 PF03165.16 CBY24633.1 - 2e-07 31.2 0.3 4.3e-07 30.1 0.3 1.7 1 0 0 1 1 1 1 MH1 domain RL10P_insert PF17777.1 CBY24633.1 - 0.093 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P Pkinase PF00069.25 CBY24634.1 - 2.4e-20 73.0 0.0 4.1e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24634.1 - 3.1e-15 56.2 0.0 6.1e-15 55.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY24634.1 - 7.4e-05 22.2 0.0 0.00017 21.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY24634.1 - 0.013 14.8 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CECR6_TMEM121 PF14997.6 CBY24638.1 - 5e-18 65.6 6.1 5.8e-18 65.4 6.1 1.1 1 0 0 1 1 1 1 CECR6/TMEM121 family DUF4190 PF13828.6 CBY24638.1 - 0.88 9.4 0.0 0.88 9.4 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) Ank_5 PF13857.6 CBY24639.1 - 3.7e-05 23.9 0.4 0.018 15.3 0.1 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24639.1 - 0.00021 21.4 0.1 6.4 7.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 CBY24639.1 - 0.0018 18.8 0.8 0.029 14.9 1.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY24639.1 - 0.003 18.1 1.8 1.3 9.6 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY24639.1 - 0.043 14.3 0.1 1.2 9.7 0.0 3.0 3 1 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 CBY24640.1 - 4.2e-05 23.7 0.0 0.039 14.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24640.1 - 0.0029 18.0 0.0 0.37 11.5 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CBY24640.1 - 0.01 16.4 0.0 1.3 9.6 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) CECR6_TMEM121 PF14997.6 CBY24641.1 - 9.1e-16 58.3 4.6 1e-15 58.1 4.6 1.0 1 0 0 1 1 1 1 CECR6/TMEM121 family DUF4190 PF13828.6 CBY24641.1 - 0.12 12.1 0.5 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Kei1 PF08552.11 CBY24641.1 - 0.26 11.1 2.4 0.9 9.4 2.4 1.8 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ank_5 PF13857.6 CBY24642.1 - 5.6e-06 26.5 0.5 0.018 15.3 0.1 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24642.1 - 0.00021 21.5 0.1 6.4 7.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 CBY24642.1 - 0.00071 20.1 1.9 1.3 9.6 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY24642.1 - 0.0019 18.8 0.9 0.031 14.9 1.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY24642.1 - 0.044 14.2 0.1 1.2 9.7 0.0 3.0 3 1 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 CBY24643.1 - 4.2e-05 23.7 0.0 0.039 14.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24643.1 - 0.0029 18.0 0.0 0.37 11.5 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CBY24643.1 - 0.01 16.4 0.0 1.3 9.6 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) DPPIV_N PF00930.21 CBY24644.1 - 1.4e-36 126.0 12.2 4.2e-36 124.4 12.2 1.7 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CBY24644.1 - 8e-33 113.7 2.8 1.5e-32 112.8 2.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family SPOC PF07744.13 CBY24646.1 - 8.4e-28 97.2 0.0 1.6e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 CBY24647.1 - 1.3e-17 63.3 3.0 1.2e-11 44.3 0.2 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECH_1 PF00378.20 CBY24649.1 - 1.4e-11 44.2 0.1 1.6e-11 44.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY24649.1 - 7.1e-09 35.6 0.0 8.7e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBY24650.1 - 1.5e-18 67.1 0.0 1.8e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY24650.1 - 9.4e-08 31.9 0.1 4.5e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase zf-CCCH PF00642.24 CBY24651.1 - 7.3e-07 28.9 13.6 0.00064 19.6 2.3 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBY24651.1 - 2e-05 24.2 9.0 0.035 13.9 3.7 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY24651.1 - 3 8.0 18.4 8.6 6.6 0.4 3.6 3 0 0 3 3 3 0 Zinc finger domain ParD_antitoxin PF03693.14 CBY24652.1 - 0.096 13.1 0.1 0.27 11.7 0.1 1.8 1 1 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH TIL PF01826.17 CBY24653.1 - 1.1e-05 25.6 23.9 7.7e-05 22.9 13.8 2.5 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain TIL PF01826.17 CBY24654.1 - 9.5e-62 205.1 159.4 1.8e-11 44.1 18.3 7.1 7 0 0 7 7 7 7 Trypsin Inhibitor like cysteine rich domain Y_phosphatase PF00102.27 CBY24655.1 - 2.4e-63 213.8 0.1 3.4e-63 213.3 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY24655.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Mito_carr PF00153.27 CBY24656.1 - 7e-45 150.9 1.2 1.1e-18 66.9 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CBY24656.1 - 0.011 15.0 0.6 2.7 7.1 0.1 2.8 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Tim17 PF02466.19 CBY24656.1 - 0.17 12.3 3.4 0.28 11.6 0.3 2.4 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family CD20 PF04103.15 CBY24657.1 - 0.73 9.9 5.5 0.79 9.8 0.5 2.2 1 1 1 2 2 2 0 CD20-like family DUF2178 PF09946.9 CBY24657.1 - 2.8 8.2 6.1 0.25 11.5 1.6 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) Fibrillarin PF01269.17 CBY24658.1 - 2.1e-107 357.4 0.1 2.5e-107 357.2 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CBY24658.1 - 0.00016 21.4 0.1 0.00025 20.8 0.1 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CBY24658.1 - 0.05 13.3 0.0 0.1 12.4 0.0 1.4 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 CBY24658.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 CBY24658.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F XK-related PF09815.9 CBY24659.1 - 5.6e-13 48.7 20.0 5.6e-13 48.7 20.0 1.7 2 0 0 2 2 2 1 XK-related protein Prefoldin PF02996.17 CBY24660.1 - 3.6e-23 81.7 0.6 4.5e-23 81.4 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Vps51 PF08700.11 CBY24660.1 - 0.0055 16.8 0.5 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Med9 PF07544.13 CBY24660.1 - 0.012 15.7 1.0 0.022 14.8 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_3 PF13758.6 CBY24660.1 - 0.015 15.4 1.1 0.094 12.8 1.3 2.0 1 1 0 1 1 1 0 Prefoldin subunit GIT_CC PF16559.5 CBY24660.1 - 1.8 8.5 8.9 0.28 11.1 4.1 2.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor GWT1 PF06423.12 CBY24663.1 - 1.1e-26 93.7 2.6 1.1e-26 93.7 2.6 2.0 2 0 0 2 2 2 1 GWT1 UNC-50 PF05216.13 CBY24663.1 - 0.17 11.4 7.3 0.55 9.8 0.2 3.1 2 1 1 3 3 3 0 UNC-50 family Glycolytic PF00274.19 CBY24664.1 - 1.7e-176 586.1 0.0 1.9e-176 586.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I ECH_1 PF00378.20 CBY24665.1 - 1e-24 87.2 0.0 1.3e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY24665.1 - 0.00054 19.6 0.0 0.00089 18.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CBY24665.1 - 0.0011 18.9 0.1 1.1 9.3 0.1 2.5 2 0 0 2 2 2 2 Peptidase family S49 CC PF04942.14 CBY24665.1 - 0.087 13.0 0.5 0.16 12.2 0.5 1.3 1 0 0 1 1 1 0 CC domain KH_1 PF00013.29 CBY24667.1 - 1.7e-25 88.6 4.8 2.1e-13 49.8 0.1 2.6 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 CBY24667.1 - 7.6e-11 41.7 9.0 1.3e-10 41.0 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY24667.1 - 0.00068 19.5 10.6 0.0013 18.6 10.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY24667.1 - 0.0014 18.4 12.4 0.0026 17.6 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_2 PF07650.17 CBY24667.1 - 0.012 15.5 2.7 2.2 8.2 0.0 3.1 3 0 0 3 3 3 0 KH domain KH_4 PF13083.6 CBY24667.1 - 0.073 13.0 0.0 2.4 8.1 0.0 2.7 2 0 0 2 2 2 0 KH domain zf-RING_5 PF14634.6 CBY24667.1 - 0.15 12.0 11.2 0.27 11.2 11.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain KH_5 PF13184.6 CBY24667.1 - 0.25 11.5 1.2 12 6.1 0.1 3.1 3 0 0 3 3 3 0 NusA-like KH domain BAR_3 PF16746.5 CBY24668.1 - 0.0047 16.7 5.9 0.0075 16.0 1.7 2.1 2 0 0 2 2 2 1 BAR domain of APPL family Cbl_N PF02262.16 CBY24668.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 Syntaxin_2 PF14523.6 CBY24668.1 - 0.14 12.5 0.3 0.14 12.5 0.3 2.0 2 0 0 2 2 2 0 Syntaxin-like protein Ank_2 PF12796.7 CBY24669.1 - 6.6e-37 126.0 12.4 2e-09 37.9 0.4 4.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY24669.1 - 1.6e-27 95.5 4.0 5.4e-10 39.6 0.0 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY24669.1 - 3.3e-23 81.4 6.3 4e-09 36.6 0.3 6.2 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24669.1 - 6.4e-21 72.2 5.4 6.2e-07 29.2 0.1 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CBY24669.1 - 1.6e-20 72.5 6.2 1.7e-05 25.0 0.2 6.0 6 0 0 6 6 6 4 Ankyrin repeat DUF615 PF04751.14 CBY24669.1 - 0.026 14.5 1.3 2.5 8.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF615) NIF PF03031.18 CBY24671.1 - 7.8e-17 61.5 0.4 3e-16 59.6 0.4 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 CBY24671.1 - 2.8e-08 33.6 0.1 6.5e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CBY24671.1 - 3.9e-05 24.0 0.0 0.00025 21.3 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CBY24671.1 - 0.046 14.0 0.1 0.16 12.3 0.1 2.0 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PPP4R2 PF09184.11 CBY24671.1 - 0.32 10.6 26.3 0.012 15.2 5.9 2.2 2 0 0 2 2 2 0 PPP4R2 MM_CoA_mutase PF01642.22 CBY24672.1 - 2.3e-239 795.2 0.1 2.7e-239 795.0 0.1 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 CBY24672.1 - 3.6e-14 52.8 0.3 8.4e-14 51.6 0.3 1.6 1 0 0 1 1 1 1 B12 binding domain EMP24_GP25L PF01105.24 CBY24673.1 - 2.3e-53 180.8 1.4 2.7e-53 180.6 1.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MbeD_MobD PF04899.12 CBY24674.1 - 0.04 14.0 2.7 5.3 7.2 0.1 3.2 2 1 1 3 3 3 0 MbeD/MobD like Ribosomal_L20 PF00453.18 CBY24674.1 - 0.32 11.1 7.8 0.75 9.9 0.8 2.4 2 0 0 2 2 2 0 Ribosomal protein L20 Prismane PF03063.20 CBY24674.1 - 0.37 9.4 5.1 0.48 9.1 5.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF4201 PF13870.6 CBY24674.1 - 0.57 9.9 30.4 2.5 7.8 2.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 CBY24674.1 - 0.6 9.4 12.7 0.26 10.6 4.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Metal_resist PF13801.6 CBY24674.1 - 0.94 9.7 11.3 0.9 9.7 3.4 3.0 1 1 2 3 3 3 0 Heavy-metal resistance Myb_DNA-bind_3 PF12776.7 CBY24674.1 - 2.7 9.0 5.3 1.2 10.1 1.6 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain AcylCoA_dehyd_C PF12186.8 CBY24674.1 - 3.6 7.7 10.0 1.4 9.1 0.6 3.0 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal kleA_kleC PF17383.2 CBY24674.1 - 3.7 7.9 13.9 8.9 6.7 0.2 4.4 2 2 2 4 4 4 0 Uncharacterized KorC regulated protein A PEP-utilisers_N PF05524.13 CBY24674.1 - 5 7.3 8.2 0.78 9.9 2.4 2.2 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal YabA PF06156.13 CBY24674.1 - 5 7.8 22.6 0.83 10.3 2.7 3.3 1 1 1 2 2 1 0 Initiation control protein YabA CorA PF01544.18 CBY24674.1 - 8.5 5.6 9.4 29 3.9 7.1 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein dsrm PF00035.26 CBY24675.1 - 1.1e-27 96.5 19.0 1.7e-06 28.6 0.4 7.4 7 1 0 7 7 7 7 Double-stranded RNA binding motif ArsC PF03960.15 CBY24675.1 - 0.14 12.2 0.0 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 ArsC family LPP20 PF02169.16 CBY24675.1 - 0.45 10.9 8.1 1.4 9.3 0.0 4.3 3 1 0 4 4 4 0 LPP20 lipoprotein Acyl-CoA_dh_1 PF00441.24 CBY24676.1 - 1.9e-47 161.3 0.2 2.9e-47 160.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY24676.1 - 7.9e-26 90.1 0.0 1.3e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY24676.1 - 3.8e-24 85.5 0.1 6.8e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY24676.1 - 1.1e-16 61.4 0.1 1.6e-16 60.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ureidogly_lyase PF04115.12 CBY24677.1 - 0.03 14.1 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Ureidoglycolate lyase MJ1316 PF04457.12 CBY24678.1 - 1.4e-23 83.4 1.3 2.9e-23 82.4 1.3 1.5 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain RWD PF05773.22 CBY24678.1 - 0.0026 18.1 0.8 0.0054 17.0 0.1 1.9 1 1 1 2 2 2 1 RWD domain LicD PF04991.13 CBY24678.1 - 0.01 16.0 2.6 0.014 15.6 2.1 1.2 1 1 0 1 1 1 0 LicD family Band_7 PF01145.25 CBY24679.1 - 1.3e-30 106.7 0.1 1.8e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY24679.1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family FYVE_2 PF02318.16 CBY24683.1 - 0.0048 17.1 0.1 0.0094 16.2 0.1 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 CBY24685.1 - 3.8e-05 23.5 13.1 3.8e-05 23.5 13.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY24685.1 - 0.00032 20.5 7.8 0.00032 20.5 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 CBY24685.1 - 0.0048 17.3 7.5 0.0091 16.4 7.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CBY24685.1 - 0.0071 16.7 9.8 0.0071 16.7 9.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.6 CBY24685.1 - 0.018 14.9 11.5 0.018 14.9 11.5 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CBY24685.1 - 6.9 6.7 19.1 1.8 8.6 13.7 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Trypsin PF00089.26 CBY24686.1 - 3.7e-39 134.8 2.4 1.2e-37 129.9 2.4 2.6 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.15 CBY24686.1 - 0.037 13.6 0.0 0.28 10.7 0.0 2.1 1 1 1 2 2 2 0 Chymotrypsin family Peptidase-S1 zf-C3HC4_3 PF13920.6 CBY24687.1 - 3e-05 23.8 13.5 3e-05 23.8 13.5 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY24687.1 - 3.2e-05 24.2 16.4 3.2e-05 24.2 16.4 3.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY24687.1 - 9.1e-05 22.2 15.7 9.1e-05 22.2 15.7 3.5 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY24687.1 - 0.00039 20.2 16.4 0.00039 20.2 16.4 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY24687.1 - 0.00045 20.3 11.1 0.00045 20.3 11.1 2.4 1 1 2 3 3 3 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 CBY24687.1 - 0.0018 18.2 15.6 0.0018 18.2 15.6 3.4 3 2 0 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.6 CBY24687.1 - 0.0082 16.0 7.2 0.0082 16.0 7.2 1.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY24687.1 - 0.012 15.5 12.9 0.012 15.5 12.9 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DUF4581 PF15167.6 CBY24687.1 - 0.017 15.2 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) zf-C3HC4_4 PF15227.6 CBY24687.1 - 0.018 15.2 23.6 0.061 13.5 15.9 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RAG1 PF10426.9 CBY24687.1 - 0.19 11.9 0.0 0.19 11.9 0.0 2.9 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain zf-P11 PF03854.14 CBY24687.1 - 4.1 7.1 16.5 0.21 11.2 9.8 2.2 2 0 0 2 2 2 0 P-11 zinc finger DUF1644 PF07800.12 CBY24687.1 - 6.7 6.8 17.5 0.3 11.2 7.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1644) LCAT PF02450.15 CBY24688.1 - 0.099 11.8 0.1 0.1 11.8 0.1 1.0 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ribosomal_S19 PF00203.21 CBY24689.1 - 5.7e-28 96.6 0.1 6.5e-28 96.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 PIN_6 PF17146.4 CBY24690.1 - 1.9e-30 105.2 0.1 3.7e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CBY24690.1 - 1.4e-22 79.7 2.8 2.9e-22 78.6 2.8 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 CBY24690.1 - 0.057 13.5 1.0 0.13 12.4 1.0 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-NADH-PPase PF09297.11 CBY24690.1 - 0.093 12.4 0.5 0.093 12.4 0.5 1.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ntox1 PF15500.6 CBY24690.1 - 0.1 12.9 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Nudix_N_2 PF14803.6 CBY24690.1 - 0.21 11.5 3.9 0.44 10.5 0.9 2.4 2 0 0 2 2 2 0 Nudix N-terminal Cys_rich_KTR PF14205.6 CBY24690.1 - 1.8 8.4 5.8 0.14 12.0 0.7 1.8 2 0 0 2 2 2 0 Cysteine-rich KTR zinc_ribbon_4 PF13717.6 CBY24690.1 - 7.4 6.6 6.9 1.1e+02 2.8 3.7 3.5 2 1 1 3 3 3 0 zinc-ribbon domain SM-ATX PF14438.6 CBY24691.1 - 1.5e-16 60.2 0.1 3.8e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 CBY24691.1 - 2.7e-12 47.0 2.1 2.7e-12 47.0 2.1 2.4 2 0 0 2 2 2 1 LsmAD domain PAM2 PF07145.15 CBY24691.1 - 0.01 15.5 2.7 3.8 7.4 0.1 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region GvpG PF05120.12 CBY24691.1 - 0.014 15.3 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 Gas vesicle protein G eIF-3_zeta PF05091.12 CBY24691.1 - 0.15 11.0 14.2 0.38 9.7 14.2 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SET PF00856.28 CBY24692.1 - 3e-09 37.5 0.2 3e-09 37.5 0.2 2.4 2 2 0 2 2 2 1 SET domain zf-MYND PF01753.18 CBY24692.1 - 1.1e-08 35.0 17.3 1.1e-08 35.0 17.3 2.0 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.6 CBY24692.1 - 0.0057 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat PolC_DP2 PF03833.13 CBY24692.1 - 0.12 10.2 0.4 0.2 9.4 0.4 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 XK-related PF09815.9 CBY24693.1 - 0.0024 17.0 0.1 0.0028 16.8 0.1 1.1 1 0 0 1 1 1 1 XK-related protein SieB PF14163.6 CBY24693.1 - 0.12 11.8 1.0 0.28 10.7 1.0 1.6 1 1 0 1 1 1 0 Super-infection exclusion protein B fn3 PF00041.21 CBY24695.1 - 5e-27 94.1 5.3 5.5e-12 45.9 0.1 3.6 3 1 0 3 3 3 3 Fibronectin type III domain Interfer-bind PF09294.10 CBY24695.1 - 4.9e-11 42.9 0.1 0.00033 20.9 0.0 3.3 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 CBY24695.1 - 1.7e-10 41.4 3.9 2.1e-05 25.0 0.0 4.1 3 2 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 CBY24695.1 - 5.8e-05 22.9 2.7 0.087 12.7 0.2 3.3 3 2 1 4 4 4 2 Tissue factor fn3_2 PF16893.5 CBY24695.1 - 0.00032 20.8 1.5 0.38 10.9 0.3 3.4 3 1 0 3 3 3 2 Fibronectin type III domain DUF3284 PF11687.8 CBY24695.1 - 0.0021 17.9 0.4 8.5 6.3 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3284) DUF5581 PF17744.1 CBY24695.1 - 0.038 13.4 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5581) RWD PF05773.22 CBY24696.1 - 1.3e-18 67.4 3.1 2.4e-18 66.5 3.1 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 CBY24696.1 - 4.7e-15 55.6 34.9 1.4e-08 34.8 1.3 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CBY24696.1 - 1.2e-05 25.5 7.8 1.2e-05 25.5 7.8 4.0 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY24696.1 - 0.0002 21.3 7.3 0.0002 21.3 7.3 3.3 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY24696.1 - 0.00035 20.4 9.1 0.00035 20.4 9.1 4.5 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY24696.1 - 0.0004 20.3 8.5 0.0004 20.3 8.5 4.1 4 1 0 4 4 4 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY24696.1 - 0.033 14.0 33.4 0.087 12.7 7.1 5.0 3 2 1 4 4 4 0 Prokaryotic RING finger family 4 DUF386 PF04074.12 CBY24696.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 YhcH/YjgK/YiaL zf-ACC PF17848.1 CBY24696.1 - 0.14 12.2 10.5 0.93 9.6 0.1 3.7 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 CBY24696.1 - 0.3 10.7 7.9 4.9 6.8 0.2 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 CBY24696.1 - 4.1 7.5 12.4 0.81 9.7 0.1 3.8 2 1 2 4 4 4 0 CpXC protein DUF1682 PF07946.14 CBY24697.1 - 0.31 10.2 6.0 0.31 10.2 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NFACT-R_1 PF05670.13 CBY24698.1 - 1.4e-41 141.5 0.0 2.4e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF1682 PF07946.14 CBY24698.1 - 0.031 13.5 7.3 0.044 13.0 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PDZ_2 PF13180.6 CBY24699.1 - 5.9e-06 26.5 0.0 1.8e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY24699.1 - 6e-06 26.0 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY24699.1 - 0.0001 22.6 0.0 0.00026 21.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Myb_DNA-binding PF00249.31 CBY24699.1 - 0.00013 22.1 0.4 0.00039 20.6 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY24699.1 - 0.0039 17.4 0.4 0.015 15.5 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBY24699.1 - 0.0093 15.8 0.4 0.069 13.1 0.4 2.7 1 0 0 1 1 1 1 Myb DNA-binding like NFACT-R_1 PF05670.13 CBY24700.1 - 1.7e-13 51.2 0.1 2e-13 50.9 0.1 1.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_1 PF05670.13 CBY24702.1 - 8.1e-12 45.8 0.0 2.8e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain PDZ_2 PF13180.6 CBY24702.1 - 6.3e-06 26.4 0.0 2e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY24702.1 - 6.4e-06 25.9 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY24702.1 - 0.00011 22.5 0.0 0.00028 21.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Myb_DNA-binding PF00249.31 CBY24702.1 - 0.00014 22.0 0.4 0.00042 20.5 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY24702.1 - 0.0042 17.3 0.4 0.017 15.4 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBY24702.1 - 0.0099 15.7 0.4 0.075 12.9 0.4 2.7 1 0 0 1 1 1 1 Myb DNA-binding like DUF2259 PF10016.9 CBY24702.1 - 9.4 6.1 7.1 2.2 8.2 2.5 2.2 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) Pkinase PF00069.25 CBY24703.1 - 4.3e-28 98.4 0.0 5.1e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24703.1 - 1.6e-17 63.7 0.0 2.5e-17 63.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY24703.1 - 1.4e-08 34.0 0.1 1.9e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY24703.1 - 0.00034 20.6 0.0 0.00086 19.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBY24703.1 - 0.0061 15.6 0.1 0.0091 15.0 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CBY24703.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 CBY24704.1 - 1.4e-12 47.6 0.0 7.3e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY24704.1 - 3.5e-11 43.2 0.3 3.7e-05 23.9 0.1 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBY24704.1 - 0.00042 20.2 1.5 0.042 13.8 0.3 2.4 2 0 0 2 2 2 1 Myb DNA-binding like EcoRII-C PF09019.11 CBY24704.1 - 0.00069 19.7 0.4 1.4 9.0 0.1 2.3 2 0 0 2 2 2 2 EcoRII C terminal SLIDE PF09111.10 CBY24704.1 - 0.0007 19.6 0.2 0.27 11.3 0.0 2.8 2 0 0 2 2 2 1 SLIDE Glyco_transf_8C PF08437.10 CBY24704.1 - 0.012 15.6 0.0 8.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal DUF2967 PF11179.8 CBY24704.1 - 0.036 12.2 0.1 0.27 9.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) CPSase_L_D2 PF02786.17 CBY24704.1 - 0.037 13.5 0.1 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain TFX_C PF14601.6 CBY24704.1 - 0.046 13.7 0.1 12 6.0 0.0 2.3 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term DapB_N PF01113.20 CBY24704.1 - 0.11 12.7 0.0 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GPW_gp25 PF04965.14 CBY24704.1 - 0.12 12.2 0.9 2.4 8.0 0.2 2.4 2 0 0 2 2 2 0 Gene 25-like lysozyme EMC3_TMCO1 PF01956.16 CBY24704.1 - 0.33 10.6 1.9 22 4.8 0.1 2.7 2 1 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like AARP2CN PF08142.12 CBY24705.1 - 1.2e-29 102.3 0.0 2.3e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 CBY24705.1 - 0.0011 19.4 0.0 0.0027 18.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CBY24705.1 - 0.0018 18.3 0.1 0.0036 17.4 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBY24705.1 - 0.0019 18.6 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 CBY24705.1 - 0.0044 16.3 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 CBY24705.1 - 0.0067 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBY24705.1 - 0.007 16.4 0.6 0.022 14.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 CBY24705.1 - 0.018 15.5 0.1 0.038 14.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 CBY24705.1 - 0.031 14.5 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CBY24705.1 - 0.035 13.9 0.1 0.099 12.4 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CBY24705.1 - 0.048 14.2 0.2 0.21 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 CBY24705.1 - 0.064 13.2 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 CBY24705.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CBY24705.1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBY24705.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.27 CBY24705.1 - 0.14 11.6 0.1 2.6 7.5 0.0 2.2 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ArgoN PF16486.5 CBY24706.1 - 6.8e-05 23.5 0.1 0.00011 22.9 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CBY24706.1 - 0.00013 21.6 0.1 0.48 10.1 0.0 2.6 3 0 0 3 3 3 2 Argonaute linker 1 domain HipN PF18253.1 CBY24706.1 - 0.098 12.4 0.2 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain VasI PF11319.8 CBY24708.1 - 0.0043 16.7 0.0 0.0047 16.6 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system VasI, EvfG, VC_A0118 Glyco_transf_64 PF09258.10 CBY24709.1 - 6.3e-62 209.0 0.3 7.4e-62 208.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain AAA_6 PF12774.7 CBY24711.1 - 4.8e-153 508.9 0.0 8e-153 508.2 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBY24711.1 - 1.6e-148 495.1 20.6 5e-101 338.7 6.3 3.8 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 Dynein_AAA_lid PF17852.1 CBY24711.1 - 4.2e-29 101.2 0.7 1.5e-28 99.4 0.7 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBY24711.1 - 4.7e-11 42.8 0.0 2.6e-05 24.2 0.0 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CBY24711.1 - 0.00024 21.5 1.4 0.19 12.2 0.1 4.5 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBY24711.1 - 0.0028 18.2 0.0 0.65 10.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain SQS_PSY PF00494.19 CBY24711.1 - 0.053 13.0 0.1 3.1 7.2 0.1 2.6 2 0 0 2 2 2 0 Squalene/phytoene synthase Phospholip_A2_1 PF00068.19 CBY24712.1 - 2.6e-15 56.9 6.1 2.6e-15 56.9 6.1 2.8 3 0 0 3 3 3 1 Phospholipase A2 PLA2G12 PF06951.11 CBY24712.1 - 0.033 14.1 1.0 0.033 14.1 1.0 2.9 2 1 0 3 3 3 0 Group XII secretory phospholipase A2 precursor (PLA2G12) EF-hand_1 PF00036.32 CBY24713.1 - 3.9e-17 60.4 4.0 1.1e-06 27.8 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY24713.1 - 4.1e-17 62.4 1.5 8.3e-08 32.6 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY24713.1 - 6.1e-16 56.9 1.2 4.3e-06 26.2 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBY24713.1 - 4.9e-13 48.7 4.9 2e-06 27.5 0.2 4.3 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY24713.1 - 1.4e-10 40.2 4.3 0.00022 20.6 0.1 3.3 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 CBY24713.1 - 0.00067 19.6 1.8 0.05 13.6 0.1 3.0 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY24713.1 - 0.015 15.6 0.1 0.92 9.9 0.0 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.11 CBY24713.1 - 0.061 13.5 0.0 19 5.4 0.0 2.8 2 2 1 3 3 3 0 EF hand EF-hand_3 PF09069.11 CBY24713.1 - 0.15 12.5 0.2 0.57 10.6 0.1 2.0 2 1 0 2 2 2 0 EF-hand BTB_2 PF02214.22 CBY24714.1 - 1.1e-10 41.7 0.3 2.1e-10 40.8 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 CBY24714.1 - 1.3e-08 34.4 2.2 1.3e-08 34.4 2.2 2.1 1 1 1 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 CBY24714.1 - 9.2e-08 31.9 4.6 9.2e-08 31.9 4.6 1.8 2 0 0 2 2 2 1 Ion channel TMEM43 PF07787.12 CBY24714.1 - 0.77 9.1 4.1 0.61 9.4 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 43 CUE PF02845.16 CBY24716.1 - 1.2 8.9 2.9 3.9 7.3 0.1 3.0 3 0 0 3 3 3 0 CUE domain zf-H2C2_5 PF13909.6 CBY24717.1 - 0.00026 20.7 4.8 0.00026 20.7 4.8 2.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CBY24717.1 - 0.016 15.6 5.7 0.016 15.6 5.7 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type CRM1_repeat_2 PF18784.1 CBY24717.1 - 0.12 12.0 0.7 0.32 10.7 0.7 1.6 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 zf-RING_5 PF14634.6 CBY24718.1 - 0.0071 16.3 2.3 0.012 15.5 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF3450 PF11932.8 CBY24718.1 - 0.039 13.3 20.8 0.12 11.7 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 CBY24718.1 - 0.24 11.1 17.8 0.37 10.5 17.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 CBY24718.1 - 0.32 11.1 15.4 0.49 10.5 15.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C3HC4_3 PF13920.6 CBY24718.1 - 0.32 10.9 2.1 0.85 9.5 2.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY24718.1 - 0.39 10.8 3.5 0.72 9.9 3.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger HALZ PF02183.18 CBY24718.1 - 0.69 10.2 0.1 0.69 10.2 0.1 3.9 3 1 1 4 4 4 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 CBY24718.1 - 1.9 8.6 21.6 8.5 6.6 8.4 3.8 1 1 3 4 4 4 0 bZIP transcription factor Exonuc_VII_L PF02601.15 CBY24718.1 - 2.4 7.6 12.1 3.6 7.1 12.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med9 PF07544.13 CBY24718.1 - 2.6 8.2 18.6 0.13 12.4 3.6 3.1 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TMPIT PF07851.13 CBY24718.1 - 3.1 6.9 9.8 0.86 8.8 0.6 2.1 2 0 0 2 2 2 0 TMPIT-like protein NES_C_h PF18208.1 CBY24718.1 - 4.5 7.6 15.3 10 6.4 10.5 2.8 1 1 2 3 3 3 0 Nicking enzyme C-terminal middle helical domain JIP_LZII PF16471.5 CBY24718.1 - 7.8 6.8 24.8 2.7 8.2 7.4 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II CENP-H PF05837.12 CBY24718.1 - 9.9 6.6 21.8 2.1 8.8 1.9 2.4 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Folate_rec PF03024.14 CBY24719.1 - 1.8e-07 31.2 20.7 8.6e-07 29.0 19.8 2.3 1 1 1 2 2 2 1 Folate receptor family Podoplanin PF05808.11 CBY24719.1 - 0.00023 21.3 2.9 0.00047 20.3 2.9 1.4 1 0 0 1 1 1 1 Podoplanin Trypsin PF00089.26 CBY24720.1 - 2e-30 106.3 0.2 2.6e-30 105.9 0.2 1.2 1 0 0 1 1 1 1 Trypsin MOSC PF03473.17 CBY24722.1 - 1.2e-21 77.1 0.0 2.5e-21 76.1 0.0 1.5 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 CBY24722.1 - 1.5e-15 57.2 0.0 2.9e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Chitin_synth_2 PF03142.15 CBY24723.1 - 1.5e-26 93.2 1.3 7.1e-24 84.3 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 CBY24723.1 - 5.9e-07 29.6 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY24723.1 - 2.9e-06 27.3 6.7 2.9e-06 27.3 6.7 3.4 2 2 0 2 2 2 1 Glycosyl transferase family group 2 OATP PF03137.20 CBY24724.1 - 1.2e-58 198.8 1.3 1.3e-58 198.7 1.3 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CBY24724.1 - 8.1e-09 34.9 17.3 2.1e-08 33.5 17.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CbtA PF09490.10 CBY24724.1 - 0.77 9.5 3.6 2.6 7.8 1.8 2.5 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) DUF4976 PF16347.5 CBY24726.1 - 6.2e-05 23.2 0.7 0.00011 22.5 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase PF00884.23 CBY24727.1 - 4.8e-11 42.6 0.0 5.3e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY24727.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CBY24727.1 - 0.15 11.4 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.23 CBY24728.1 - 2.1e-07 30.7 0.8 3.5e-06 26.6 0.8 2.0 1 1 0 1 1 1 1 Sulfatase Sep15_SelM PF08806.11 CBY24728.1 - 0.083 13.1 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Sep15/SelM redox domain Prefoldin PF02996.17 CBY24729.1 - 1.8e-13 50.4 0.4 3e-13 49.7 0.4 1.3 1 0 0 1 1 1 1 Prefoldin subunit BcrAD_BadFG PF01869.20 CBY24730.1 - 3.3e-19 69.4 0.1 3.6e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DUF2709 PF10915.8 CBY24730.1 - 0.062 12.6 0.5 0.18 11.1 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2709) EF-hand_1 PF00036.32 CBY24731.1 - 2.5e-09 36.0 0.0 0.014 14.9 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CBY24731.1 - 4.5e-07 29.1 0.0 0.083 12.4 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY24731.1 - 7.7e-06 25.4 0.0 0.13 12.3 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY24731.1 - 0.0025 18.2 0.0 3.2 8.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY24731.1 - 0.012 15.5 0.1 3.1 7.7 0.1 3.1 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_4 PF12763.7 CBY24731.1 - 0.041 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand IU_nuc_hydro PF01156.19 CBY24732.1 - 2.5e-06 27.3 0.2 2.8e-06 27.1 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.19 CBY24733.1 - 9.3e-29 101.0 0.0 1.1e-28 100.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FH2 PF02181.23 CBY24734.1 - 2e-18 66.7 1.2 3.5e-18 65.9 1.2 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CBY24734.1 - 0.00036 20.2 0.1 0.00099 18.8 0.1 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain Trypsin PF00089.26 CBY24735.1 - 9.7e-49 166.2 0.2 1.7e-48 165.4 0.2 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY24735.1 - 0.00063 20.7 0.0 0.0013 19.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Endonuc-BglII PF09195.11 CBY24735.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease BglII SUI1 PF01253.22 CBY24738.1 - 5.7e-21 74.8 0.3 9.6e-21 74.1 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 eIF-5_eIF-2B PF01873.17 CBY24738.1 - 0.066 13.1 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 EamA PF00892.20 CBY24739.1 - 6.7e-28 97.6 21.7 1.3e-14 54.5 7.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 CBY24739.1 - 0.0015 18.1 9.2 0.0024 17.4 9.2 1.5 1 1 0 1 1 1 1 Solute carrier family 35 Multi_Drug_Res PF00893.19 CBY24739.1 - 0.84 10.3 8.8 0.78 10.4 0.4 3.3 2 1 1 3 3 3 0 Small Multidrug Resistance protein HMG_CoA_synt_N PF01154.17 CBY24740.1 - 1.1e-84 282.6 0.2 1.7e-84 282.0 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 CBY24740.1 - 2e-82 277.0 0.2 2.8e-82 276.5 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Herpes_UL4 PF03277.13 CBY24740.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL4 family LRR_5 PF13306.6 CBY24740.1 - 0.16 11.9 1.6 0.93 9.5 0.1 2.4 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) ACP_syn_III_C PF08541.10 CBY24740.1 - 0.17 12.1 0.0 0.84 9.9 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF962 PF06127.11 CBY24741.1 - 1.1e-21 76.7 9.2 8.2e-21 73.9 9.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DEAD PF00270.29 CBY24742.1 - 1.1e-42 145.8 0.7 2.2e-42 144.8 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY24742.1 - 6e-19 68.4 0.1 1.3e-17 64.1 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBY24742.1 - 1.5e-15 57.2 0.2 4e-15 55.8 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBY24742.1 - 8.9e-08 32.3 0.2 8.9e-08 32.3 0.2 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBY24742.1 - 0.042 14.2 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Sec_GG PF07549.14 CBY24742.1 - 0.14 11.7 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif Borrelia_P83 PF05262.11 CBY24742.1 - 0.86 8.0 21.3 1.4 7.3 20.8 1.6 2 0 0 2 2 2 0 Borrelia P83/100 protein SMAP PF15477.6 CBY24743.1 - 1.1e-09 39.2 1.4 1.1e-09 39.2 1.4 2.9 2 1 0 2 2 2 1 Small acidic protein family DUF5427 PF10310.9 CBY24743.1 - 1.3 7.9 17.6 1.5 7.7 17.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 CBY24743.1 - 6.8 5.3 14.3 7.4 5.2 14.3 1.2 1 0 0 1 1 1 0 Presenilin FERM_M PF00373.18 CBY24744.1 - 1.3e-19 70.8 1.3 2.9e-19 69.6 1.3 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CBY24744.1 - 1.6e-07 31.1 0.0 1.7e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.10 CBY24744.1 - 3.8e-07 30.4 0.0 1.6e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 FERM C-terminal PH-like domain Zona_pellucida PF00100.23 CBY24745.1 - 6.4e-23 81.9 2.8 6.4e-23 81.9 2.8 1.4 2 0 0 2 2 2 1 Zona pellucida-like domain NKWYS PF10364.9 CBY24745.1 - 0.038 14.1 0.8 0.094 12.8 0.8 1.7 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein LRR_6 PF13516.6 CBY24749.1 - 7.4e-08 31.9 2.9 0.0021 18.0 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 CBY24749.1 - 9.8e-06 25.8 1.2 0.011 16.1 0.1 2.7 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY24749.1 - 3.2e-05 23.6 3.1 0.0031 17.2 0.4 2.3 2 0 0 2 2 2 2 Leucine rich repeat TetR_C_2 PF08361.11 CBY24749.1 - 0.047 13.8 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Sigma_reg_N PF13800.6 CBY24750.1 - 0.028 14.7 0.5 0.041 14.2 0.5 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PsbM PF05151.12 CBY24750.1 - 5.2 7.0 6.6 9 6.2 6.6 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) Sulfotransfer_3 PF13469.6 CBY24751.1 - 2e-15 57.8 0.0 4.8e-15 56.5 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY24751.1 - 4.3e-13 49.4 0.7 2.8e-12 46.7 0.7 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Glyco_hydro_79n PF03662.14 CBY24752.1 - 3.7e-66 223.2 0.0 4.8e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain CO_dh PF02552.16 CBY24753.1 - 0.11 12.3 0.5 0.13 12.0 0.5 1.1 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit CIDR1_gamma PF18562.1 CBY24753.1 - 1.1 9.5 6.5 2.3 8.4 6.5 1.7 1 1 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma EMP24_GP25L PF01105.24 CBY24754.1 - 7.3e-13 48.9 0.0 1.2e-12 48.2 0.0 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CC PF04942.14 CBY24757.1 - 0.019 15.1 0.1 0.021 15.0 0.1 1.3 1 0 0 1 1 1 0 CC domain PLA2G12 PF06951.11 CBY24758.1 - 0.051 13.5 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) 5-FTHF_cyc-lig PF01812.20 CBY24760.1 - 3.5e-23 82.4 0.2 1.7e-22 80.2 0.0 1.7 1 1 1 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family DUF1947 PF09183.10 CBY24760.1 - 0.55 10.6 3.3 0.33 11.3 0.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1947) Mito_carr PF00153.27 CBY24761.1 - 2.6e-54 181.1 6.8 1.8e-24 85.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CBY24761.1 - 0.077 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Fuseless Glyco_transf_64 PF09258.10 CBY24763.1 - 5.8e-25 88.0 0.1 9.4e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 CBY24763.1 - 1e-09 38.0 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Pkinase PF00069.25 CBY24764.1 - 1.5e-68 231.0 0.0 2.1e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24764.1 - 2.1e-29 102.6 0.0 2.9e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBY24764.1 - 0.003 18.0 0.3 0.0091 16.5 0.3 1.8 1 1 0 1 1 1 1 PH domain Hairy_orange PF07527.13 CBY24764.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Hairy Orange Gal_Lectin PF02140.18 CBY24765.1 - 1.3e-16 60.8 2.0 2.5e-16 59.9 2.0 1.5 1 0 0 1 1 1 1 Galactose binding lectin domain Gal_Lectin PF02140.18 CBY24766.1 - 2e-16 60.1 2.2 4.3e-16 59.1 2.2 1.6 1 0 0 1 1 1 1 Galactose binding lectin domain zf-RING_5 PF14634.6 CBY24767.1 - 4.7e-06 26.5 11.8 4e-05 23.5 7.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY24767.1 - 1.1e-05 25.7 7.8 1.1e-05 25.7 7.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY24767.1 - 1.4e-05 25.0 4.8 1.4e-05 25.0 4.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY24767.1 - 0.00018 21.3 15.9 0.00042 20.1 10.0 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY24767.1 - 0.00062 19.6 17.1 0.012 15.4 11.0 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) HMMR_N PF15905.5 CBY24767.1 - 0.0013 18.3 9.3 0.002 17.7 9.3 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal zf-C3HC4_2 PF13923.6 CBY24767.1 - 0.0056 16.5 18.1 0.0086 15.9 11.8 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Vhr1 PF04001.13 CBY24767.1 - 0.0058 16.9 0.3 0.019 15.3 0.3 1.9 1 0 0 1 1 1 1 Transcription factor Vhr1 Spc7 PF08317.11 CBY24767.1 - 0.0058 15.5 11.5 0.0094 14.9 11.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TolA_bind_tri PF16331.5 CBY24767.1 - 0.0061 16.6 1.9 0.0061 16.6 1.9 2.2 1 1 2 3 3 2 1 TolA binding protein trimerisation Exonuc_VII_L PF02601.15 CBY24767.1 - 0.0063 16.1 2.0 0.0063 16.1 2.0 1.6 2 0 0 2 2 2 1 Exonuclease VII, large subunit zf-C3HC4_5 PF17121.5 CBY24767.1 - 0.0085 16.0 5.2 0.0085 16.0 5.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY24767.1 - 0.0088 15.8 12.3 0.37 10.6 7.7 2.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain CALCOCO1 PF07888.11 CBY24767.1 - 0.013 14.4 12.3 0.019 13.8 12.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Zn_Tnp_IS91 PF14319.6 CBY24767.1 - 0.016 15.2 8.9 0.53 10.4 3.1 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Nup54 PF13874.6 CBY24767.1 - 0.028 14.5 4.1 0.07 13.2 4.1 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Anillin_N PF16018.5 CBY24767.1 - 0.041 14.5 0.0 0.27 11.9 0.0 2.5 1 1 1 2 2 1 0 Anillin N-terminus Prok-RING_4 PF14447.6 CBY24767.1 - 0.043 13.7 16.6 0.1 12.5 4.4 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Cluap1 PF10234.9 CBY24767.1 - 0.043 13.2 11.0 0.034 13.5 9.1 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 DHR10 PF18595.1 CBY24767.1 - 0.046 13.8 12.9 0.092 12.8 12.9 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Sec34 PF04136.15 CBY24767.1 - 0.055 13.3 4.0 0.1 12.5 4.0 1.4 1 0 0 1 1 1 0 Sec34-like family ADIP PF11559.8 CBY24767.1 - 0.077 13.1 12.5 0.27 11.3 12.2 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Phage_GPO PF05929.11 CBY24767.1 - 0.1 12.2 4.7 0.18 11.4 4.7 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3450 PF11932.8 CBY24767.1 - 0.12 11.6 6.9 0.21 10.8 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 CBY24767.1 - 0.18 12.4 4.7 0.43 11.2 4.7 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal IBR PF01485.21 CBY24767.1 - 0.19 11.9 13.0 0.57 10.5 7.5 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 CBY24767.1 - 0.26 11.4 9.3 0.69 10.1 3.1 2.4 2 0 0 2 2 2 0 FYVE zinc finger TPR_MLP1_2 PF07926.12 CBY24767.1 - 0.35 10.9 11.6 0.71 9.9 11.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Enkurin PF13864.6 CBY24767.1 - 0.37 11.3 8.1 0.16 12.4 3.5 2.5 1 1 1 2 2 2 0 Calmodulin-binding V_ATPase_I PF01496.19 CBY24767.1 - 0.42 8.5 7.6 0.57 8.0 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 CBY24767.1 - 0.46 10.7 12.4 1.1 9.5 12.4 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.11 CBY24767.1 - 0.47 10.3 7.3 0.2 11.5 4.7 1.7 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) DUF16 PF01519.16 CBY24767.1 - 0.48 10.9 8.9 0.41 11.1 6.7 2.1 2 0 0 2 2 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 CBY24767.1 - 1 9.4 8.0 2.4 8.2 6.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 CBY24767.1 - 1.1 9.7 14.4 2.5 8.5 14.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) SlyX PF04102.12 CBY24767.1 - 1.1 9.9 4.6 3.3 8.4 3.7 2.3 1 1 1 2 2 2 0 SlyX Cep57_MT_bd PF06657.13 CBY24767.1 - 1.2 9.7 6.5 0.79 10.2 2.9 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF948 PF06103.11 CBY24767.1 - 1.2 9.5 3.9 1.9 8.8 2.5 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 CBY24767.1 - 1.2 9.7 11.6 0.42 11.3 3.9 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 CBY24767.1 - 1.3 8.8 11.1 0.51 10.1 6.2 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF4795 PF16043.5 CBY24767.1 - 1.4 8.5 12.8 27 4.3 12.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 CBY24767.1 - 1.6 8.0 8.8 0.087 12.2 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-C3HC4_4 PF15227.6 CBY24767.1 - 1.7 8.8 11.8 4.1 7.7 7.2 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prefoldin PF02996.17 CBY24767.1 - 2.7 7.9 9.9 1.5 8.7 3.4 2.6 1 1 0 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.8 CBY24767.1 - 3.1 7.8 16.7 0.33 11.0 8.7 2.6 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.9 CBY24767.1 - 7.1 7.4 6.7 36 5.1 6.7 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CENP-H PF05837.12 CBY24767.1 - 7.9 6.9 12.1 14 6.1 10.7 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 CBY24767.1 - 8.1 5.6 9.7 13 4.9 7.6 1.8 1 1 1 2 2 2 0 TMPIT-like protein ABC_tran_CTD PF16326.5 CBY24767.1 - 8.9 6.6 12.0 9 6.6 1.5 2.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain Piwi PF02171.17 CBY24769.1 - 7.3e-64 215.9 0.0 1.1e-63 215.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CBY24769.1 - 1.6e-08 34.4 0.0 3.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 CBY24769.1 - 0.0013 18.9 0.0 0.0054 17.0 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 CBY24769.1 - 0.0016 18.7 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoN PF16486.5 CBY24769.1 - 0.0044 17.6 0.2 0.012 16.2 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CBY24769.1 - 0.038 13.7 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Argonaute linker 1 domain KH_1 PF00013.29 CBY24770.1 - 1.7e-60 200.7 8.1 7.2e-17 61.0 0.0 4.2 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 CBY24770.1 - 1.2e-19 69.5 28.3 9.8e-08 31.4 5.5 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_2 PF07650.17 CBY24770.1 - 2e-19 69.2 6.3 4.5e-05 23.2 2.8 4.7 3 1 1 4 4 4 4 KH domain KH_4 PF13083.6 CBY24770.1 - 2.5e-12 46.5 5.2 0.0071 16.2 0.2 4.3 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 CBY24770.1 - 0.2 11.7 8.6 11 6.1 0.1 4.1 4 0 0 4 4 4 0 NusA-like KH domain PLDc_2 PF13091.6 CBY24771.1 - 3e-27 95.1 0.5 5.4e-27 94.3 0.3 1.5 2 0 0 2 2 2 1 PLD-like domain FAM83 PF07894.12 CBY24771.1 - 0.0085 15.7 0.4 0.056 13.0 0.4 2.0 1 1 0 1 1 1 1 FAM83 A-H NADH_4Fe-4S PF10589.9 CBY24771.1 - 0.013 15.6 0.2 0.025 14.6 0.2 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PLDc PF00614.22 CBY24771.1 - 0.042 14.0 0.1 0.24 11.6 0.1 2.1 2 0 0 2 2 2 0 Phospholipase D Active site motif DUF2024 PF09630.10 CBY24771.1 - 0.63 9.9 3.2 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) DUF4706 PF15797.5 CBY24772.1 - 5.9e-26 91.1 1.8 5.9e-26 91.1 1.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4706) ATP-synt_E PF05680.12 CBY24772.1 - 4.1 7.8 7.3 25 5.3 0.1 2.9 3 0 0 3 3 3 0 ATP synthase E chain CTP_transf_like PF01467.26 CBY24773.1 - 3.7e-27 95.3 0.0 6.4e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF2362 PF10154.9 CBY24774.1 - 4e-64 217.4 10.4 1.3e-39 136.5 2.5 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2362) PXB PF12828.7 CBY24775.1 - 0.091 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 PX-associated DUF4499 PF14934.6 CBY24776.1 - 4.8e-28 97.3 0.7 6.2e-28 97.0 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) TRAPP PF04051.16 CBY24777.1 - 1.9e-35 121.7 0.0 2.2e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LSM PF01423.22 CBY24778.1 - 8.6e-17 60.6 0.2 1.1e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY24778.1 - 0.00011 22.3 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain JAB PF01398.21 CBY24779.1 - 1.4e-32 112.2 0.0 2.4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CBY24779.1 - 2.6e-12 47.1 0.6 4.9e-12 46.3 0.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CBY24779.1 - 9.4e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF89 PF01937.19 CBY24779.1 - 0.05 12.5 0.1 0.066 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 DUF5624 PF18538.1 CBY24779.1 - 0.095 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) UPRTase PF14681.6 CBY24781.1 - 1.9e-51 174.4 0.1 2.6e-51 174.0 0.1 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CBY24781.1 - 9.3e-05 22.0 0.0 0.00013 21.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Carb_kinase PF01256.17 CBY24781.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase CASP_C PF08172.12 CBY24782.1 - 0.0083 15.5 0.2 0.0083 15.5 0.2 1.1 1 0 0 1 1 1 1 CASP C terminal DUF2353 PF09789.9 CBY24782.1 - 0.03 13.7 0.8 0.03 13.7 0.8 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) BACK PF07707.15 CBY24782.1 - 0.051 13.7 0.1 0.056 13.5 0.1 1.1 1 0 0 1 1 1 0 BTB And C-terminal Kelch Plus-3 PF03126.18 CBY24783.1 - 2.5e-26 92.3 0.0 7.6e-26 90.8 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain GCK PF07802.11 CBY24784.1 - 0.047 14.1 1.9 0.047 14.1 0.3 1.8 2 0 0 2 2 2 0 GCK domain CHCH PF06747.13 CBY24784.1 - 0.096 12.9 2.2 6.6 7.0 0.3 2.3 2 0 0 2 2 2 0 CHCH domain EamA PF00892.20 CBY24785.1 - 8.2e-14 51.9 19.6 8.2e-12 45.5 6.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family Inhibitor_Mig-6 PF11555.8 CBY24787.1 - 0.17 12.0 0.2 25 5.0 0.0 2.4 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 TSP_1 PF00090.19 CBY24788.1 - 0.012 15.8 0.1 0.021 15.0 0.1 1.5 1 1 0 1 1 1 0 Thrombospondin type 1 domain DUF3149 PF11346.8 CBY24788.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Glyco_tran_10_N PF17039.5 CBY24789.1 - 4e-18 65.9 0.5 2.4e-17 63.4 0.0 2.3 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 CBY24789.1 - 3.5e-15 56.2 1.4 1.2e-12 47.9 0.6 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) C-term Ank_2 PF12796.7 CBY24790.1 - 1.6e-09 38.2 0.1 2.6e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY24790.1 - 1.4e-08 35.1 0.1 0.0037 17.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY24790.1 - 4.1e-06 27.0 0.2 0.0078 16.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY24790.1 - 7.5e-05 22.8 0.1 4.7 8.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CBY24790.1 - 0.00015 22.1 0.5 0.076 13.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat BLACT_WH PF17778.1 CBY24790.1 - 0.017 15.1 0.8 1.9 8.5 0.2 2.4 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain OTU PF02338.19 CBY24791.1 - 7.5e-18 65.3 0.4 4.7e-17 62.7 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CBY24791.1 - 2.5e-06 27.1 1.0 0.054 12.9 0.0 2.9 2 1 1 3 3 3 2 Peptidase C65 Otubain Chromo PF00385.24 CBY24791.1 - 0.00029 20.7 0.1 0.00077 19.3 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF5347 PF17282.2 CBY24791.1 - 0.028 14.7 0.7 0.32 11.3 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5347) PWWP PF00855.17 CBY24791.1 - 0.045 14.1 0.3 0.045 14.1 0.3 1.8 2 0 0 2 2 2 0 PWWP domain UCR_14kD PF02271.16 CBY24791.1 - 0.051 13.5 0.1 8 6.5 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Kinesin PF00225.23 CBY24792.1 - 4.7e-97 324.9 0.4 4.7e-97 324.9 0.4 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY24792.1 - 1.5e-29 102.9 2.6 1.5e-29 102.8 0.2 2.2 2 0 0 2 2 2 1 Microtubule binding PIF1 PF05970.14 CBY24792.1 - 0.035 13.3 0.3 0.093 11.9 0.3 1.7 1 0 0 1 1 1 0 PIF1-like helicase Homoserine_dh PF00742.19 CBY24792.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase Mvb12 PF09452.10 CBY24792.1 - 0.21 12.0 3.3 1.4 9.4 0.3 3.2 3 1 0 3 3 3 0 ESCRT-I subunit Mvb12 AAA_16 PF13191.6 CBY24792.1 - 0.25 11.7 2.7 18 5.7 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain BST2 PF16716.5 CBY24792.1 - 0.29 11.7 8.9 0.23 12.1 2.3 2.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Exo84_C PF16528.5 CBY24792.1 - 0.79 9.5 7.3 0.26 11.1 2.7 2.5 2 0 0 2 2 2 0 Exocyst component 84 C-terminal Cep57_CLD_2 PF14197.6 CBY24792.1 - 4.4 7.5 9.4 6.2 7.0 4.1 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DNA_pol_A_exo1 PF01612.20 CBY24793.1 - 4.6e-14 52.5 0.0 7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Stc1 PF12898.7 CBY24793.1 - 0.021 15.4 0.5 0.059 13.9 0.5 1.8 1 0 0 1 1 1 0 Stc1 domain DAGK_cat PF00781.24 CBY24794.1 - 1.8e-25 88.9 0.1 3.4e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PAS_6 PF08348.11 CBY24794.1 - 0.043 13.7 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 YheO-like PAS domain Polysacc_synt_4 PF04669.13 CBY24795.1 - 2.4e-07 30.5 0.0 0.00047 19.8 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis Polysacc_synt_4 PF04669.13 CBY24796.1 - 3.6e-11 43.0 0.1 0.00012 21.7 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis MADF_DNA_bdg PF10545.9 CBY24796.1 - 0.0024 18.1 0.2 0.0043 17.3 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Polysacc_synt_4 PF04669.13 CBY24797.1 - 6.9e-10 38.8 0.1 1e-06 28.5 0.0 2.3 1 1 1 2 2 2 2 Polysaccharide biosynthesis PepSY_like PF11396.8 CBY24797.1 - 0.0033 17.9 0.1 0.0072 16.8 0.1 1.6 1 1 0 1 1 1 1 Putative beta-lactamase-inhibitor-like, PepSY-like Zip PF02535.22 CBY24797.1 - 3.7 6.7 8.2 6.3 5.9 8.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Polysacc_synt_4 PF04669.13 CBY24799.1 - 2.1e-10 40.5 0.1 0.00034 20.2 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis LBR_tudor PF09465.10 CBY24800.1 - 0.078 12.8 0.0 0.089 12.6 0.0 1.1 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Polysacc_synt_4 PF04669.13 CBY24801.1 - 2.7e-17 63.0 0.1 1.3e-15 57.5 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis UCMA PF17085.5 CBY24801.1 - 0.0089 16.0 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Unique cartilage matrix associated protein YkyA PF10368.9 CBY24801.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein vATP-synt_E PF01991.18 CBY24802.1 - 3.3e-29 101.7 0.3 3.6e-29 101.6 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit LCD1 PF09798.9 CBY24802.1 - 0.0092 14.5 0.0 0.0092 14.5 0.0 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein DMAP1 PF05499.12 CBY24804.1 - 8.6e-26 90.8 2.2 2.1e-25 89.6 2.2 1.6 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 CBY24804.1 - 1.2e-18 67.1 0.6 2.7e-18 66.0 0.6 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Ntox1 PF15500.6 CBY24804.1 - 0.011 16.1 1.4 0.022 15.1 1.4 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 HECT PF00632.25 CBY24805.1 - 1.4e-91 307.2 0.0 1.9e-91 306.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CBY24805.1 - 2.5e-47 158.6 25.4 1.4e-13 50.7 4.0 4.7 4 0 0 4 4 4 4 WW domain C2 PF00168.30 CBY24805.1 - 4.3e-18 65.5 0.1 1.3e-17 63.9 0.1 1.9 1 0 0 1 1 1 1 C2 domain Ras PF00071.22 CBY24806.1 - 1.2e-25 90.0 0.0 1.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY24806.1 - 4.8e-09 36.5 0.0 7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBY24806.1 - 1.6e-05 24.9 0.0 2.7e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBY24806.1 - 7e-05 22.3 0.0 8.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DAP3 PF10236.9 CBY24806.1 - 0.0012 18.0 0.1 0.3 10.2 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.6 CBY24806.1 - 0.0033 17.7 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 CBY24806.1 - 0.0059 16.7 0.1 0.026 14.6 0.1 2.1 1 1 0 1 1 1 1 Dynamin family SRPRB PF09439.10 CBY24806.1 - 0.028 13.8 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Mon1 PF03164.14 CBY24806.1 - 0.086 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 Flavin_Reduct PF01613.18 CBY24806.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Flavin reductase like domain AAA_14 PF13173.6 CBY24806.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cep57_CLD PF14073.6 CBY24807.1 - 3.9e-10 40.1 14.7 3.9e-10 40.1 14.7 3.6 2 2 0 3 3 3 1 Centrosome localisation domain of Cep57 ING PF12998.7 CBY24807.1 - 8.8 7.0 19.5 0.26 11.9 3.3 3.1 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding GCH_III PF05165.12 CBY24808.1 - 0.028 13.7 0.2 0.034 13.4 0.2 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase III Sds3 PF08598.11 CBY24808.1 - 0.037 14.0 0.8 0.037 14.0 0.8 1.5 2 0 0 2 2 2 0 Sds3-like DUF1690 PF07956.11 CBY24808.1 - 0.12 12.8 12.2 1 9.8 12.2 2.1 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF4600 PF15372.6 CBY24808.1 - 0.15 12.5 7.0 0.062 13.7 4.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF1664 PF07889.12 CBY24808.1 - 0.27 11.3 1.7 0.5 10.4 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF349 PF03993.12 CBY24808.1 - 1.3 9.4 13.8 0.68 10.3 2.4 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Remorin_C PF03763.13 CBY24808.1 - 1.8 8.5 9.3 0.37 10.7 5.8 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region DUF2870 PF11069.8 CBY24809.1 - 1.3e-40 137.6 1.4 2.7e-40 136.7 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) PSP1 PF04468.12 CBY24809.1 - 0.043 14.1 0.5 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 PSP1 C-terminal conserved region ubiquitin PF00240.23 CBY24809.1 - 0.081 12.7 0.3 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin family Ras PF00071.22 CBY24810.1 - 2.6e-23 82.4 0.0 3.8e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY24810.1 - 7.9e-05 22.9 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_75 PF07335.11 CBY24810.1 - 0.15 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 DUF3456 PF11938.8 CBY24811.1 - 9.7e-06 26.2 2.6 0.00054 20.5 0.6 2.9 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.13 CBY24811.1 - 0.00026 21.3 16.1 0.00026 21.3 16.1 3.8 3 0 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.24 CBY24811.1 - 0.0027 17.8 11.1 0.0027 17.8 11.1 4.5 2 1 2 4 4 4 1 Laminin EGF domain ALG3 PF05208.13 CBY24813.1 - 2.1e-37 129.4 1.0 2.7e-37 129.0 1.0 1.1 1 0 0 1 1 1 1 ALG3 protein ALG3 PF05208.13 CBY24814.1 - 1.3e-61 209.0 15.3 1.3e-61 209.0 15.3 1.8 2 0 0 2 2 2 1 ALG3 protein TERT_thumb PF17984.1 CBY24814.1 - 1.6 8.6 7.1 0.14 12.0 1.4 1.9 2 0 0 2 2 2 0 Telomerase reverse transcriptase thumb DNA binding domain bZIP_1 PF00170.21 CBY24815.1 - 6.3e-07 29.4 10.7 1.2e-06 28.5 9.6 2.1 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 CBY24815.1 - 9.5e-05 22.4 9.1 9.5e-05 22.4 9.1 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 CBY24815.1 - 0.0044 17.5 8.0 0.0044 17.5 8.0 2.1 2 1 0 2 2 2 1 bZIP Maf transcription factor TPR_MLP1_2 PF07926.12 CBY24815.1 - 0.0063 16.6 2.8 0.0063 16.6 2.8 2.3 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 CBY24815.1 - 0.03 14.2 6.1 0.071 12.9 6.1 1.7 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 CBY24815.1 - 0.046 13.7 1.1 0.046 13.7 1.1 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Amino_oxidase PF01593.24 CBY24815.1 - 0.068 12.4 2.5 0.9 8.8 0.0 2.0 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase JMY PF15871.5 CBY24815.1 - 1.1 8.5 9.4 0.31 10.3 5.8 1.7 2 0 0 2 2 2 0 Junction-mediating and -regulatory protein Fez1 PF06818.15 CBY24815.1 - 3.5 8.0 15.1 0.75 10.2 5.0 2.2 1 1 1 2 2 2 0 Fez1 SOGA PF11365.8 CBY24815.1 - 6.9 7.9 12.1 4.6 8.4 5.9 3.1 2 1 1 3 3 3 0 Protein SOGA Spc24 PF08286.11 CBY24815.1 - 9.7 6.5 7.5 6 7.2 1.0 2.7 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Use1 PF09753.9 CBY24816.1 - 0.00048 19.9 0.0 0.00051 19.8 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 sCache_like PF16736.5 CBY24816.1 - 0.11 12.6 1.2 0.14 12.3 1.2 1.2 1 0 0 1 1 1 0 Single Cache-like SRP9-21 PF05486.12 CBY24817.1 - 0.00063 20.1 0.2 0.019 15.4 0.2 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) PPV_E2_C PF00511.17 CBY24817.1 - 0.033 14.4 0.1 0.041 14.1 0.1 1.2 1 0 0 1 1 1 0 E2 (early) protein, C terminal ATP-synt_ab PF00006.25 CBY24818.1 - 4.7e-68 229.0 0.0 6.9e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBY24818.1 - 3e-12 46.9 0.3 5.4e-12 46.1 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 CBY24818.1 - 0.21 10.4 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TPR_2 PF07719.17 CBY24819.1 - 9.7e-11 40.9 1.0 0.00022 21.1 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY24819.1 - 1.5e-08 34.2 0.0 0.0012 18.5 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.28 CBY24819.1 - 3.2e-07 29.9 1.6 0.0094 15.7 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY24819.1 - 4.2e-05 24.0 0.3 0.44 11.5 0.0 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY24819.1 - 0.00012 22.0 0.5 0.23 11.8 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY24819.1 - 0.00013 22.6 0.2 0.3 11.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY24819.1 - 0.0024 18.3 0.3 0.8 10.3 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY24819.1 - 0.0026 17.9 0.4 1.1 9.5 0.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY24819.1 - 0.0028 17.8 0.8 0.51 10.6 0.1 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CBY24819.1 - 0.0052 17.0 1.3 2.1 8.7 0.3 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY24819.1 - 0.0095 16.3 3.2 0.032 14.6 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 CBY24819.1 - 0.02 13.9 0.1 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Pneumo_M2 PF07380.11 CBY24819.1 - 0.061 13.6 0.2 9.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Pneumovirus M2 protein U-box PF04564.15 CBY24820.1 - 4e-25 87.8 0.1 7.4e-25 86.9 0.1 1.5 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 CBY24820.1 - 6e-19 68.6 10.8 6e-19 68.6 10.8 2.0 2 0 0 2 2 2 1 CHIP N-terminal tetratricopeptide repeat domain TPR_2 PF07719.17 CBY24820.1 - 1.8e-13 49.5 5.9 0.0021 18.0 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY24820.1 - 1.2e-12 47.1 3.6 0.0002 21.0 0.7 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY24820.1 - 2.6e-10 40.4 1.7 4.8e-10 39.5 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY24820.1 - 1.9e-07 31.4 0.4 0.0083 16.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY24820.1 - 2.4e-07 31.3 0.1 0.0012 19.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY24820.1 - 4e-07 29.6 2.2 0.00026 20.6 0.3 3.0 1 1 2 3 3 3 2 TPR repeat TPR_12 PF13424.6 CBY24820.1 - 1.7e-05 25.0 3.8 0.11 12.8 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY24820.1 - 2.5e-05 24.3 0.0 0.15 12.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY24820.1 - 6.7e-05 22.8 11.9 0.15 12.4 0.1 4.1 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY24820.1 - 0.00024 21.5 2.3 3.2 8.6 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY24820.1 - 0.00079 20.1 0.3 1.9 9.5 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.10 CBY24820.1 - 0.0013 17.8 0.2 0.0025 16.9 0.1 1.4 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) zf-NOSIP PF15906.5 CBY24820.1 - 0.066 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein SRP_TPR_like PF17004.5 CBY24820.1 - 0.2 11.7 9.3 5.9 6.9 1.6 3.3 1 1 0 2 2 2 0 Putative TPR-like repeat DUF4337 PF14235.6 CBY24820.1 - 1.9 8.6 14.5 0.067 13.3 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) ubiquitin PF00240.23 CBY24821.1 - 1e-05 25.1 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family HEAT_2 PF13646.6 CBY24821.1 - 0.0026 18.1 1.8 0.028 14.8 0.6 3.2 4 1 0 4 4 4 1 HEAT repeats V-ATPase_H_N PF03224.14 CBY24821.1 - 0.0083 15.4 0.7 2.1 7.6 0.1 2.9 2 1 0 2 2 2 2 V-ATPase subunit H DUF2070 PF09843.9 CBY24821.1 - 0.83 7.9 8.6 1.3 7.2 8.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RGS PF00615.19 CBY24822.1 - 9.6e-24 83.9 0.0 2.1e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain RBD PF02196.15 CBY24822.1 - 4.1e-12 46.0 0.0 6.4e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Raf-like Ras-binding domain SART-1 PF03343.13 CBY24823.1 - 0.00023 19.9 21.2 0.00032 19.4 21.2 1.1 1 0 0 1 1 1 1 SART-1 family Spore_coat_CotO PF14153.6 CBY24823.1 - 6.4 6.7 21.1 0.71 9.8 16.3 1.9 2 0 0 2 2 2 0 Spore coat protein CotO PCI PF01399.27 CBY24824.1 - 4.3e-11 43.3 0.1 1.1e-08 35.5 0.0 3.5 4 1 0 4 4 4 1 PCI domain eIF3m_C_helix PF18005.1 CBY24824.1 - 4.9e-09 35.7 1.0 4.9e-09 35.7 1.0 2.0 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix SWI-SNF_Ssr4 PF08549.10 CBY24824.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Sacchrp_dh_NADP PF03435.18 CBY24825.1 - 7e-18 65.2 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CBY24825.1 - 8.1e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CBY24825.1 - 0.015 14.4 0.0 0.031 13.3 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ephrin_lbd PF01404.19 CBY24826.1 - 3e-11 43.7 0.0 5.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Ribosomal_60s PF00428.19 CBY24826.1 - 0.00072 20.1 0.1 0.0018 18.8 0.1 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein FXa_inhibition PF14670.6 CBY24826.1 - 1.5 9.2 4.1 4.2 7.7 4.1 1.8 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY24826.1 - 2.6 8.1 7.5 0.18 11.8 1.6 2.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like COesterase PF00135.28 CBY24827.1 - 5.8e-53 180.5 0.3 1.6e-52 179.1 0.1 1.7 1 1 1 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY24827.1 - 5.5e-06 26.4 0.4 2.8e-05 24.1 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold RabGAP-TBC PF00566.18 CBY24829.1 - 1.2e-39 136.2 0.4 1.2e-39 136.2 0.4 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FAM76 PF16046.5 CBY24829.1 - 1 8.7 12.2 1.6 8.0 12.2 1.3 1 0 0 1 1 1 0 FAM76 protein Ig_3 PF13927.6 CBY24831.1 - 3.6e-12 46.7 0.3 1.2e-07 32.2 0.0 4.2 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CBY24831.1 - 5.6e-12 45.6 0.1 3.1e-08 33.6 0.0 4.1 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY24831.1 - 7.7e-08 32.6 0.1 0.0017 18.6 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 CBY24831.1 - 3.1e-05 24.0 0.0 0.0018 18.4 0.0 3.0 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CBY24831.1 - 0.00034 20.8 0.0 0.0043 17.2 0.0 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 CBY24831.1 - 0.076 13.2 0.0 0.35 11.1 0.0 2.1 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Ig_4 PF16680.5 CBY24831.1 - 0.092 13.0 0.1 3.5 8.0 0.0 2.7 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain S1FA PF04689.13 CBY24831.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA CPSase_L_D2 PF02786.17 CBY24832.1 - 5.6e-72 241.7 0.0 1.1e-71 240.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBY24832.1 - 2.2e-46 156.9 0.6 8.2e-45 151.9 0.1 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBY24832.1 - 5.5e-36 122.9 0.0 1.8e-35 121.3 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBY24832.1 - 5e-15 55.1 5.7 5.7e-15 54.9 3.9 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CBY24832.1 - 2e-11 43.8 0.0 6.7e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBY24832.1 - 2.8e-09 36.8 0.0 6.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CBY24832.1 - 6.3e-06 25.9 0.2 0.00044 20.0 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like RimK PF08443.11 CBY24832.1 - 2.6e-05 23.9 0.0 0.00021 20.9 0.0 2.3 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 CBY24832.1 - 5.8e-05 23.8 0.2 0.095 13.4 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 CBY24832.1 - 0.00042 20.4 0.1 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain DUF2118 PF09891.9 CBY24832.1 - 0.0013 18.7 0.3 0.2 11.6 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_D23 PF16576.5 CBY24832.1 - 0.0034 16.6 0.9 1.4 8.1 0.2 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_Ter PF15632.6 CBY24832.1 - 0.0054 16.5 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon MinE PF03776.14 CBY24832.1 - 0.0072 16.3 0.6 0.022 14.8 0.2 2.0 2 0 0 2 2 2 1 Septum formation topological specificity factor MinE ATPgrasp_ST PF14397.6 CBY24832.1 - 0.011 14.9 0.1 0.38 10.0 0.0 2.4 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 CBY24832.1 - 0.017 15.1 0.4 0.052 13.5 0.4 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain BORA_N PF15280.6 CBY24834.1 - 3.2e-16 59.7 5.4 4.9e-15 55.8 3.3 3.0 1 1 0 1 1 1 1 Protein aurora borealis N-terminus Secretin_N_2 PF07655.13 CBY24835.1 - 0.015 15.9 1.3 0.018 15.5 1.3 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain FGGY_N PF00370.21 CBY24836.1 - 2e-18 66.9 0.0 6.2e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF2985 PF11204.8 CBY24838.1 - 0.058 13.6 0.4 0.098 12.8 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) Actin PF00022.19 CBY24839.1 - 4.3e-152 506.5 0.0 1.4e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin adh_short PF00106.25 CBY24840.1 - 4.4e-34 117.7 0.2 6.8e-34 117.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY24840.1 - 1.2e-27 97.0 0.1 1.6e-27 96.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY24840.1 - 1.1e-07 32.0 0.2 4e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CBY24840.1 - 0.00078 19.0 0.0 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 CBY24840.1 - 0.0073 16.4 0.4 0.014 15.5 0.4 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain EF-hand_5 PF13202.6 CBY24840.1 - 0.024 14.1 0.1 0.049 13.1 0.1 1.5 1 0 0 1 1 1 0 EF hand THF_DHG_CYH_C PF02882.19 CBY24840.1 - 0.024 13.9 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 CBY24840.1 - 0.036 14.0 0.1 0.051 13.5 0.1 1.7 1 1 0 1 1 1 0 NAD(P)H-binding F420_oxidored PF03807.17 CBY24840.1 - 0.069 13.7 0.1 0.19 12.3 0.0 1.7 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CBY24840.1 - 0.077 12.9 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EF-hand_7 PF13499.6 CBY24840.1 - 0.095 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair TIG PF01833.24 CBY24840.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 IPT/TIG domain EF-hand_6 PF13405.6 CBY24840.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 CBY24840.1 - 0.33 10.9 1.3 0.35 10.7 0.1 1.7 2 0 0 2 2 2 0 EF-hand domain pair Homeodomain PF00046.29 CBY24841.1 - 1.2e-22 79.5 1.1 2e-22 78.8 1.1 1.4 1 0 0 1 1 1 1 Homeodomain SatD PF16264.5 CBY24841.1 - 0.11 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 SatD family (SatD) Homeodomain PF00046.29 CBY24842.1 - 1.4e-21 76.1 3.3 1.4e-21 76.1 3.3 2.3 3 0 0 3 3 3 1 Homeodomain Ets PF00178.22 CBY24844.1 - 5.5e-35 119.7 3.7 8.5e-35 119.1 3.7 1.3 1 0 0 1 1 1 1 Ets-domain zf-RING_2 PF13639.6 CBY24845.1 - 5.6e-06 26.6 10.6 5.6e-06 26.6 10.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-CCCH_4 PF18044.1 CBY24845.1 - 4.5e-05 23.1 4.5 0.00013 21.7 4.5 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 CBY24845.1 - 5.4e-05 23.0 10.4 0.00016 21.5 10.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY24845.1 - 8.2e-05 22.4 11.3 0.00019 21.2 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 CBY24845.1 - 0.00038 20.4 5.5 0.001 19.0 5.5 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBY24845.1 - 0.00067 19.5 2.4 0.0015 18.4 2.4 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.25 CBY24845.1 - 0.0009 19.1 11.5 0.0019 18.0 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY24845.1 - 0.0011 18.9 8.7 0.0011 18.9 8.7 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY24845.1 - 0.0015 18.5 12.3 0.0015 18.5 12.3 1.7 2 0 0 2 2 1 1 zinc-RING finger domain Csm1_N PF18504.1 CBY24845.1 - 0.0059 16.9 1.4 0.011 16.1 1.4 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain CCDC24 PF15669.5 CBY24845.1 - 0.0076 16.2 0.2 0.051 13.4 0.1 2.1 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family SWI-SNF_Ssr4 PF08549.10 CBY24845.1 - 0.016 13.8 0.4 0.016 13.8 0.4 1.8 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) DUF659 PF04937.15 CBY24845.1 - 0.021 14.7 0.2 0.031 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) MAD PF05557.13 CBY24845.1 - 0.047 12.0 0.3 0.066 11.6 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TMF_DNA_bd PF12329.8 CBY24845.1 - 0.051 13.6 3.6 0.082 12.9 3.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2443 PF10398.9 CBY24845.1 - 0.057 13.5 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Geminin PF07412.12 CBY24845.1 - 0.074 12.8 0.7 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 Geminin DUF641 PF04859.12 CBY24845.1 - 0.1 12.9 0.3 0.16 12.3 0.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DivIC PF04977.15 CBY24845.1 - 0.11 12.3 0.5 0.21 11.4 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-UDP PF14569.6 CBY24845.1 - 1.3 9.2 9.7 4.5 7.5 9.4 2.1 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 CBY24845.1 - 1.8 8.4 6.9 1.1 9.1 4.7 1.8 1 1 0 1 1 1 0 RING-like zinc finger zf_CCCH_4 PF18345.1 CBY24846.1 - 2.1e-06 27.6 7.8 5.2e-06 26.3 7.8 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBY24846.1 - 3.2e-06 26.8 5.6 3.2e-06 26.8 5.6 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBY24846.1 - 5.5e-05 23.0 3.7 0.00011 21.9 3.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 CBY24846.1 - 7.8e-05 22.5 11.2 7.8e-05 22.5 11.2 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY24846.1 - 0.00014 21.7 12.1 0.0003 20.6 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY24846.1 - 0.0021 18.4 11.4 0.0021 18.4 11.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY24846.1 - 0.013 15.6 8.0 0.027 14.5 8.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-CCCH_2 PF14608.6 CBY24846.1 - 0.023 15.2 6.0 0.072 13.6 6.0 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_2 PF13923.6 CBY24846.1 - 0.024 14.5 13.6 0.24 11.3 13.6 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY24846.1 - 0.024 14.8 12.1 0.061 13.5 11.3 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBY24846.1 - 0.03 14.2 12.6 0.65 9.9 0.0 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-4CXXC_R1 PF10497.9 CBY24846.1 - 0.23 11.7 13.7 0.89 9.8 13.7 2.2 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-Di19 PF05605.12 CBY24846.1 - 0.46 10.8 8.5 0.98 9.8 6.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cornichon PF03311.14 CBY24848.1 - 1.1e-12 48.4 2.0 1.2e-12 48.2 2.0 1.1 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.14 CBY24849.1 - 2.6e-20 72.9 3.0 2.9e-20 72.8 3.0 1.0 1 0 0 1 1 1 1 Cornichon protein Plexin_cytopl PF08337.12 CBY24850.1 - 9.2e-160 533.0 5.6 1.6e-159 532.1 5.6 1.4 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 CBY24850.1 - 1.3e-08 34.7 0.7 0.0073 16.4 0.0 3.2 2 0 0 2 2 2 2 IPT/TIG domain PSI PF01437.25 CBY24850.1 - 2.8e-08 34.2 48.0 2.5e-07 31.1 12.9 4.5 4 0 0 4 4 4 3 Plexin repeat Asparaginase_2 PF01112.18 CBY24851.1 - 1.6e-32 112.7 0.1 2.2e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 Asparaginase PIN_12 PF16289.5 CBY24851.1 - 0.032 14.7 1.0 0.15 12.6 0.6 2.0 1 1 1 2 2 2 0 PIN domain Glyco_hydro_36 PF17167.4 CBY24851.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain EnY2 PF10163.9 CBY24852.1 - 6.9e-27 93.6 0.2 7.8e-27 93.5 0.2 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 GST_C PF00043.25 CBY24853.1 - 4.1e-08 33.3 0.0 7.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY24853.1 - 0.0014 18.6 0.2 0.006 16.6 0.2 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY24853.1 - 0.0035 17.5 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1b PF00579.25 CBY24854.1 - 2.9e-68 230.3 0.0 4.1e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 CBY24854.1 - 8.5e-31 105.9 0.3 1.8e-30 104.9 0.3 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Holin_BlyA PF05102.12 CBY24856.1 - 0.028 14.4 0.9 0.047 13.6 0.1 1.7 1 1 1 2 2 2 0 holin, BlyA family Zona_pellucida PF00100.23 CBY24857.1 - 2.3e-17 63.6 0.1 4.9e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.6 CBY24857.1 - 0.0085 16.3 14.4 0.014 15.6 12.7 2.3 1 1 1 2 2 2 1 Coagulation Factor Xa inhibitory site NTP_transf_2 PF01909.23 CBY24858.1 - 0.1 12.9 1.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Nucleotidyltransferase domain DNA_pol_A_exo1 PF01612.20 CBY24860.1 - 2.1e-15 56.9 0.0 4.2e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease LRR_9 PF14580.6 CBY24860.1 - 1.8e-12 47.1 0.4 3.8e-12 46.1 0.4 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBY24860.1 - 9.2e-12 44.6 7.7 2.2e-07 30.5 2.3 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY24860.1 - 3.8e-09 36.7 11.2 1.7e-05 25.1 3.9 3.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) PetG PF02529.15 CBY24860.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 LRR_1 PF00560.33 CBY24860.1 - 1.5 9.7 9.2 28 5.8 0.0 4.7 3 1 1 4 4 4 0 Leucine Rich Repeat TLP-20 PF06088.11 CBY24861.1 - 2.7 7.9 8.0 0.27 11.1 2.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ubiquitin PF00240.23 CBY24862.1 - 1.8e-14 53.2 0.1 2.9e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 CBY24862.1 - 4.9e-07 29.6 53.7 0.0056 16.6 11.4 5.5 3 1 2 5 5 5 4 STI1 domain Rad60-SLD PF11976.8 CBY24862.1 - 5.9e-07 29.2 0.1 1.1e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 CBY24862.1 - 0.0006 19.7 1.3 0.0025 17.7 1.3 2.2 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.9 CBY24862.1 - 0.0063 17.1 0.0 0.02 15.5 0.0 1.8 2 0 0 2 2 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBY24862.1 - 0.0074 16.6 0.2 0.015 15.6 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBY24862.1 - 0.0076 16.3 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like E3_UbLigase_EDD PF11547.8 CBY24862.1 - 0.0095 15.6 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD CUE PF02845.16 CBY24862.1 - 0.0095 15.6 0.0 0.04 13.6 0.0 2.1 2 0 0 2 2 2 1 CUE domain Ubiquitin_4 PF18036.1 CBY24862.1 - 0.02 14.9 0.4 0.24 11.5 0.4 2.3 1 1 0 1 1 1 0 Ubiquitin-like domain DUF3602 PF12223.8 CBY24862.1 - 0.062 13.9 0.9 0.062 13.9 0.9 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3602) LPD22 PF18834.1 CBY24862.1 - 0.27 11.5 0.0 0.27 11.5 0.0 3.9 3 2 1 4 4 4 0 Large polyvalent protein associated domain 22 RPN13_C PF16550.5 CBY24862.1 - 0.52 10.5 11.4 0.044 14.0 5.5 2.2 2 0 0 2 2 2 0 UCH-binding domain CoA_trans PF01144.23 CBY24863.1 - 9e-116 384.8 4.7 1.4e-73 246.9 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 CBY24863.1 - 0.0018 16.7 0.0 0.0027 16.1 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 CBY24863.1 - 0.06 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Forkhead PF00250.18 CBY24864.1 - 5.3e-39 132.4 0.0 8.6e-39 131.7 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Glyco_hydro_85 PF03644.13 CBY24866.1 - 5.7e-64 216.4 2.0 7.7e-64 216.0 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Beach PF02138.18 CBY24867.1 - 7e-115 383.1 3.5 7.2e-115 383.1 2.3 1.7 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 CBY24867.1 - 3.4e-07 30.3 0.0 1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 CBY24867.1 - 5.5e-06 27.0 11.8 0.041 14.8 0.3 5.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4800 PF16057.5 CBY24867.1 - 0.0018 17.6 3.1 0.0037 16.6 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) GRIM-19 PF06212.12 CBY24867.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 GRIM-19 protein DUF3361 PF11841.8 CBY24867.1 - 0.85 9.6 5.0 0.56 10.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) adh_short PF00106.25 CBY24869.1 - 9.2e-23 80.7 0.0 1.6e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY24869.1 - 3.2e-16 59.6 0.0 5.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY24869.1 - 3e-06 27.3 0.0 4.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 CBY24869.1 - 0.0098 15.9 0.2 0.056 13.4 0.2 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 CBY24869.1 - 0.022 14.2 0.1 0.48 9.8 0.0 2.1 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 CBY24869.1 - 0.044 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster4 family CIMR PF00878.18 CBY24871.1 - 4.1e-66 221.4 55.4 2.8e-12 46.9 0.0 11.5 9 3 1 11 11 11 9 Cation-independent mannose-6-phosphate receptor repeat fn2 PF00040.19 CBY24871.1 - 0.05 13.9 10.2 0.28 11.5 10.2 2.5 1 0 0 1 1 1 0 Fibronectin type II domain Acylphosphatase PF00708.18 CBY24872.1 - 0.6 10.6 5.3 1 9.8 0.1 3.7 3 0 0 3 3 3 0 Acylphosphatase APG6_N PF17675.1 CBY24872.1 - 2.4 8.7 86.9 0.21 12.1 19.0 5.6 1 1 3 5 5 5 0 Apg6 coiled-coil region TMP_2 PF06791.13 CBY24872.1 - 8.4 6.0 7.6 3.8 7.1 0.6 2.7 3 0 0 3 3 3 0 Prophage tail length tape measure protein Apolipoprotein PF01442.18 CBY24873.1 - 4.9e-05 23.3 12.2 4.9e-05 23.3 12.2 2.7 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain APG6_N PF17675.1 CBY24873.1 - 0.005 17.4 7.8 0.005 17.4 7.8 3.1 1 1 2 3 3 3 2 Apg6 coiled-coil region HMMR_N PF15905.5 CBY24873.1 - 0.0064 16.0 36.4 0.0097 15.4 15.5 2.3 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal Jnk-SapK_ap_N PF09744.9 CBY24873.1 - 0.41 10.9 36.3 9 6.5 16.2 4.0 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 VWA_2 PF13519.6 CBY24873.1 - 0.41 11.3 3.4 0.96 10.1 0.1 3.0 1 1 2 3 3 3 0 von Willebrand factor type A domain DUF5601 PF18151.1 CBY24873.1 - 0.47 10.8 11.9 1.8 9.0 2.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) Fib_alpha PF08702.10 CBY24873.1 - 0.55 10.4 32.3 0.56 10.4 9.1 4.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF2833 PF11090.8 CBY24873.1 - 0.61 10.5 3.1 4.1 7.9 0.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2833) DUF1664 PF07889.12 CBY24873.1 - 0.65 10.0 25.4 0.46 10.5 3.1 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBY24873.1 - 0.95 8.3 35.0 0.1 11.5 10.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Spidroin_N PF16763.5 CBY24873.1 - 1.5 8.8 8.4 0.24 11.4 0.7 3.0 2 1 1 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term SHE3 PF17078.5 CBY24873.1 - 1.6 8.4 34.8 3.1 7.4 31.3 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 GAS PF13851.6 CBY24873.1 - 1.6 8.0 33.6 0.29 10.5 12.8 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 CBY24873.1 - 1.9 8.9 36.4 0.042 14.3 4.6 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 CBY24873.1 - 2.5 8.2 35.5 2.2 8.3 8.8 4.0 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Med9 PF07544.13 CBY24873.1 - 3.1 8.0 19.9 0.5 10.5 2.6 3.9 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2570 PF10828.8 CBY24873.1 - 4.3 7.2 19.8 2.2 8.1 4.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) SlyX PF04102.12 CBY24873.1 - 4.3 8.0 21.1 6.4 7.5 3.1 5.3 1 1 3 4 4 4 0 SlyX DUF4407 PF14362.6 CBY24873.1 - 4.9 6.4 23.2 24 4.1 9.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.21 CBY24874.1 - 2.6e-06 27.2 68.1 0.0033 17.1 16.5 4.7 2 1 1 4 4 4 3 Intermediate filament protein DUF1664 PF07889.12 CBY24874.1 - 0.0056 16.7 9.0 0.0056 16.7 9.0 5.3 3 1 1 5 5 5 3 Protein of unknown function (DUF1664) C2-C2_1 PF11618.8 CBY24875.1 - 2.6e-32 111.8 0.0 1.7e-15 57.3 0.0 2.9 3 0 0 3 3 3 2 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 CBY24875.1 - 2.6e-16 60.0 3.6 8.3e-16 58.3 0.2 2.4 2 1 0 2 2 2 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2 PF00168.30 CBY24875.1 - 9.3e-08 32.3 0.0 1.5e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 C2 domain Rap1a PF18602.1 CBY24875.1 - 0.041 14.2 0.0 4.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Rap1a immunity proteins Chorion_2 PF03964.15 CBY24875.1 - 0.095 13.5 0.9 0.19 12.6 0.9 1.5 1 0 0 1 1 1 0 Chorion family 2 DUF5582 PF17819.1 CBY24876.1 - 6.7e-05 23.4 0.6 0.00012 22.5 0.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) EF-hand_6 PF13405.6 CBY24876.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CBY24879.1 - 2.7e-17 61.0 5.1 6.9e-08 31.5 0.2 4.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY24879.1 - 2.6e-14 51.9 7.2 4e-06 26.3 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY24879.1 - 1e-11 45.1 2.9 0.00034 21.0 1.3 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY24879.1 - 1.8e-11 42.9 8.8 1.2e-06 27.7 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY24879.1 - 7.3e-06 25.7 2.8 0.15 11.9 0.1 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CBY24879.1 - 0.022 15.1 0.3 12 6.4 0.0 3.4 2 1 1 4 4 4 0 EF-hand domain GCV_H PF01597.19 CBY24879.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein SPARC_Ca_bdg PF10591.9 CBY24879.1 - 0.085 13.2 0.1 18 5.7 0.0 3.0 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CBY24879.1 - 0.13 12.2 0.5 5.5 6.9 0.0 2.3 1 1 0 2 2 2 0 Caleosin related protein Excalibur PF05901.11 CBY24879.1 - 0.99 10.1 5.7 2.9 8.6 0.1 2.8 3 0 0 3 3 3 0 Excalibur calcium-binding domain Filament PF00038.21 CBY24880.1 - 5e-63 213.5 37.1 1.1e-62 212.5 37.1 1.4 1 1 0 1 1 1 1 Intermediate filament protein Rab5-bind PF09311.11 CBY24880.1 - 0.011 15.2 26.2 0.054 12.9 11.9 2.3 1 1 1 2 2 2 0 Rabaptin-like protein DUF775 PF05603.12 CBY24880.1 - 0.1 12.1 0.1 0.28 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF775) TPR_MLP1_2 PF07926.12 CBY24880.1 - 0.13 12.3 34.1 0.11 12.6 5.2 4.3 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CBY24880.1 - 0.52 9.1 35.1 0.15 11.0 16.7 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Nudix_hydro PF18290.1 CBY24880.1 - 3.3 7.8 5.6 6.4 6.9 0.1 3.0 3 0 0 3 3 3 0 Nudix hydrolase domain YtxH PF12732.7 CBY24880.1 - 3.6 8.2 11.3 0.79 10.3 1.2 4.1 2 2 1 3 3 3 0 YtxH-like protein Pox_A_type_inc PF04508.12 CBY24880.1 - 5.5 7.0 9.4 40 4.3 0.0 4.7 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat PIP5K PF01504.18 CBY24881.1 - 1.5e-64 217.9 5.2 1.5e-64 217.9 5.2 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF5385 PF17359.2 CBY24882.1 - 0.033 13.8 1.1 0.062 12.9 1.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Lipoprotein_18 PF06804.11 CBY24882.1 - 0.037 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein DUF1418 PF07214.12 CBY24882.1 - 0.063 13.1 0.5 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DUF5305 PF17231.2 CBY24882.1 - 0.076 12.4 1.3 0.1 12.0 0.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5305) PTPLA PF04387.14 CBY24882.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA Shisa PF13908.6 CBY24882.1 - 0.24 11.6 3.5 0.15 12.3 1.6 1.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator SIT PF15330.6 CBY24882.1 - 1.5 9.3 7.2 0.68 10.4 3.5 2.3 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Syndecan PF01034.20 CBY24882.1 - 2 8.4 3.5 3.7 7.5 3.5 1.3 1 0 0 1 1 1 0 Syndecan domain FeoB_associated PF12669.7 CBY24882.1 - 2.4 8.6 7.1 6.8 7.2 7.1 1.8 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Gal-3-0_sulfotr PF06990.11 CBY24883.1 - 2e-79 267.4 0.3 2.7e-79 266.9 0.3 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Thg1C PF14413.6 CBY24883.1 - 0.00092 19.4 0.1 0.0018 18.4 0.1 1.5 1 0 0 1 1 1 1 Thg1 C terminal domain Sulfotransfer_2 PF03567.14 CBY24883.1 - 0.0011 18.9 0.2 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase family Zona_pellucida PF00100.23 CBY24885.1 - 5.5e-26 91.9 6.2 6.5e-26 91.7 6.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.6 CBY24885.1 - 0.00077 19.7 11.1 0.004 17.4 11.1 2.3 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site PqiA PF04403.13 CBY24887.1 - 0.091 12.6 0.5 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Paraquat-inducible protein A Trypsin PF00089.26 CBY24888.1 - 2e-07 31.1 0.0 2.3e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_S6 PF02395.16 CBY24888.1 - 0.1 10.6 0.0 0.17 9.9 0.0 1.2 1 1 0 1 1 1 0 Immunoglobulin A1 protease Zona_pellucida PF00100.23 CBY24889.1 - 5.5e-26 91.9 6.2 6.5e-26 91.7 6.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.6 CBY24889.1 - 0.00077 19.7 11.1 0.004 17.4 11.1 2.3 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site PqiA PF04403.13 CBY24891.1 - 0.091 12.6 0.5 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Paraquat-inducible protein A Trypsin PF00089.26 CBY24892.1 - 3.3e-20 72.9 0.1 4.2e-20 72.5 0.1 1.0 1 0 0 1 1 1 1 Trypsin PcfK PF14058.6 CBY24903.1 - 0.005 17.1 1.9 0.0056 17.0 0.2 1.8 2 0 0 2 2 2 1 PcfK-like protein zf-TFIIB PF13453.6 CBY24903.1 - 0.033 13.5 0.8 1.7 8.1 0.0 2.7 1 1 1 2 2 2 0 Transcription factor zinc-finger LMBR1 PF04791.16 CBY24903.1 - 0.15 11.0 0.6 0.14 11.0 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PADR1 PF08063.12 CBY24903.1 - 0.23 11.2 3.7 2.9 7.7 0.1 2.6 2 1 0 2 2 2 0 PADR1 (NUC008) domain DUF43 PF01861.16 CBY24904.1 - 0.13 11.5 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Phospholip_A2_1 PF00068.19 CBY24905.1 - 1.7e-17 63.9 6.1 1.7e-17 63.9 6.1 2.0 2 0 0 2 2 2 1 Phospholipase A2 Actin PF00022.19 CBY24906.1 - 7.4e-64 215.8 0.0 8.1e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.19 CBY24907.1 - 7.7e-25 87.3 0.0 8.2e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.19 CBY24908.1 - 4.5e-31 107.9 0.1 4.7e-31 107.8 0.1 1.0 1 0 0 1 1 1 1 Actin MFS_1 PF07690.16 CBY24909.1 - 7.9e-32 110.5 34.8 1.3e-26 93.4 18.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.24 CBY24910.1 - 8.2e-43 146.5 0.2 1.2e-42 145.9 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4407 PF14362.6 CBY24910.1 - 0.65 9.3 13.6 1.7 7.9 13.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4746 PF15928.5 CBY24910.1 - 2.2 7.6 13.1 3.5 7.0 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Rtf2 PF04641.12 CBY24910.1 - 3.4 7.0 15.8 5.7 6.2 15.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.14 CBY24910.1 - 4.7 5.4 13.1 6.6 4.9 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 CBY24910.1 - 5.5 5.6 9.1 9.1 4.9 9.1 1.4 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.13 CBY24910.1 - 7.6 5.2 9.5 11 4.7 9.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRM_5 PF13893.6 CBY24911.1 - 2.4e-53 179.0 12.7 5.7e-32 109.9 0.0 6.0 3 1 2 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBY24911.1 - 5.4e-43 144.7 1.2 3e-08 33.4 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CBY24911.1 - 1.6e-21 76.3 0.9 8.3e-12 45.2 0.1 3.3 3 0 0 3 3 3 2 RRM-like domain RRM_occluded PF16842.5 CBY24911.1 - 1.2e-10 41.1 0.0 0.0011 18.7 0.0 5.3 5 0 0 5 5 5 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CBY24911.1 - 3.6e-05 23.8 0.0 4.6 7.4 0.0 4.9 5 0 0 5 5 5 2 RNA recognition motif DUF5474 PF17568.2 CBY24911.1 - 0.0061 16.6 0.0 8.1 6.6 0.0 2.9 2 0 0 2 2 2 2 Family of unknown function (DUF5474) FTH PF01827.27 CBY24911.1 - 0.018 14.8 1.1 4.6 7.0 0.0 2.8 3 0 0 3 3 3 0 FTH domain Ribosomal_L16 PF00252.18 CBY24911.1 - 0.053 13.5 0.1 19 5.3 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L16p/L10e RL PF17797.1 CBY24911.1 - 0.065 13.2 0.0 6.3 6.8 0.0 3.3 3 0 0 3 3 3 0 RL domain RPN6_C_helix PF18503.1 CBY24911.1 - 0.73 9.6 2.1 29 4.5 0.2 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain Trypsin PF00089.26 CBY24913.1 - 0.0093 15.8 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 1 Trypsin DUF2750 PF11042.8 CBY24913.1 - 0.036 14.1 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) Tme5_EGF_like PF09064.10 CBY24914.1 - 0.062 13.2 1.0 0.19 11.7 1.0 1.9 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Kelch_6 PF13964.6 CBY24915.1 - 8.3e-09 35.4 0.9 0.011 16.0 0.2 3.8 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY24915.1 - 7.7e-06 25.8 0.4 0.83 9.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY24915.1 - 8.4e-06 25.7 2.0 0.82 9.7 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY24915.1 - 0.0018 18.5 0.5 6.6 7.1 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY24915.1 - 0.0041 16.7 0.2 3.3 7.4 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CBY24915.1 - 0.039 14.0 0.4 7.9 6.6 0.0 3.5 3 0 0 3 3 3 0 Kelch motif SMAP PF15477.6 CBY24917.1 - 1.4e-12 48.4 5.0 1.4e-12 48.4 5.0 3.7 3 1 1 4 4 4 1 Small acidic protein family zf-RING_2 PF13639.6 CBY24918.1 - 5.7e-08 33.0 10.0 8.9e-08 32.3 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY24918.1 - 1.5e-05 24.8 7.5 2.5e-05 24.1 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY24918.1 - 5e-05 23.2 7.0 8.8e-05 22.4 7.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY24918.1 - 0.00011 22.0 8.1 0.00019 21.2 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY24918.1 - 0.00033 20.6 7.1 0.0005 20.0 7.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY24918.1 - 0.00038 20.3 5.5 0.00063 19.6 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY24918.1 - 0.0012 19.1 9.7 0.0031 17.8 9.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBY24918.1 - 0.11 12.3 6.6 0.25 11.1 6.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 CBY24918.1 - 0.2 11.5 4.4 0.41 10.6 4.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY24918.1 - 0.7 9.8 10.1 2.3 8.1 10.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CBY24918.1 - 0.78 9.9 4.0 3.2 8.0 4.2 1.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 CBY24918.1 - 1.3 9.2 7.1 3.9 7.7 7.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CBY24918.1 - 2.2 8.5 7.0 6.4 7.0 7.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain MFS_1 PF07690.16 CBY24920.1 - 6e-23 81.3 20.7 1.2e-22 80.3 20.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBY24920.1 - 0.00032 19.1 6.3 0.00032 19.1 6.3 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 CBY24921.1 - 3.2e-29 101.7 18.6 6.2e-22 77.7 6.0 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 CBY24921.1 - 4.2e-14 52.2 22.1 8e-10 38.2 5.7 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Trypan_PARP PF05887.11 CBY24922.1 - 0.2 11.7 20.4 0.24 11.4 20.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vinculin PF01044.19 CBY24922.1 - 2.9 6.0 6.8 3.2 5.9 6.8 1.0 1 0 0 1 1 1 0 Vinculin family DUF4366 PF14283.6 CBY24922.1 - 6 6.9 10.6 7.4 6.6 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Adeno_E1A PF02703.14 CBY24922.1 - 7.8 6.0 11.1 0.44 10.1 6.1 1.4 2 0 0 2 2 2 0 Early E1A protein 7tm_1 PF00001.21 CBY24923.1 - 2.2e-43 148.5 8.0 3e-43 148.0 8.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CBY24923.1 - 3.3e-10 39.8 5.4 4.4e-10 39.4 5.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 CBY24923.1 - 0.00015 21.4 3.6 0.00023 20.7 3.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.9 CBY24923.1 - 0.0024 17.5 12.4 0.0045 16.7 12.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Kelch_6 PF13964.6 CBY24924.1 - 0.0004 20.6 0.7 1.3 9.4 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CBY24924.1 - 0.00044 19.8 0.0 0.47 10.1 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY24924.1 - 0.0038 17.2 1.1 0.032 14.2 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Flg_new PF09479.10 CBY24924.1 - 0.084 13.1 0.4 0.17 12.1 0.4 1.4 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Phospholip_A2_1 PF00068.19 CBY24925.1 - 9e-14 51.9 5.0 9e-14 51.9 5.0 1.9 2 0 0 2 2 2 1 Phospholipase A2 PP1_bind PF15276.6 CBY24925.1 - 0.029 14.7 0.1 0.066 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein phosphatase 1 binding Peptidase_C97 PF05903.14 CBY24926.1 - 5.8e-34 117.1 0.0 6.8e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PMP22_Claudin PF00822.20 CBY24929.1 - 2.2e-05 24.4 8.2 3.2e-05 23.9 8.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY24929.1 - 5.4e-05 23.5 8.4 9.3e-05 22.7 8.4 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CBY24929.1 - 0.00046 20.0 5.0 0.00082 19.2 5.0 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.6 CBY24929.1 - 0.17 12.1 7.0 1.3 9.4 6.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2157 PF09925.9 CBY24929.1 - 0.22 11.3 0.2 0.22 11.3 0.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Pox_A14 PF05767.12 CBY24929.1 - 0.77 9.9 9.2 2 8.6 3.6 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 MIG-14_Wnt-bd PF06664.12 CBY24929.1 - 3.3 6.9 14.8 12 5.1 14.9 2.0 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF202 PF02656.15 CBY24929.1 - 5.9 7.4 6.4 0.84 10.1 1.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Trypsin PF00089.26 CBY24930.1 - 3.2e-54 184.1 0.9 6.2e-54 183.1 0.9 1.5 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY24930.1 - 0.036 15.0 0.0 0.13 13.1 0.0 2.0 1 1 0 1 1 1 0 Trypsin-like peptidase domain TSP_1 PF00090.19 CBY24931.1 - 6.3e-07 29.5 12.1 6.3e-07 29.5 12.1 4.1 3 1 0 3 3 3 3 Thrombospondin type 1 domain CAP PF00188.26 CBY24932.1 - 6.6e-17 62.5 0.8 1.1e-16 61.8 0.8 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TSP_1 PF00090.19 CBY24932.1 - 1.8e-14 53.7 29.1 6e-11 42.4 11.2 3.2 3 0 0 3 3 3 2 Thrombospondin type 1 domain DNA_photolyase PF00875.18 CBY24933.1 - 7.2e-40 136.7 0.0 1.1e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 CBY24933.1 - 3.3e-30 105.1 1.8 6.2e-30 104.2 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase CDC45 PF02724.14 CBY24936.1 - 0.11 10.7 7.4 0.12 10.7 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S8 PF00082.22 CBY24937.1 - 2.8e-45 154.9 1.4 3.7e-45 154.5 1.4 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY24937.1 - 7.5e-20 70.7 0.2 1.4e-19 69.9 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Zona_pellucida PF00100.23 CBY24938.1 - 1.4e-27 97.2 1.2 2.1e-27 96.6 1.2 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Kelch_6 PF13964.6 CBY24938.1 - 0.056 13.8 0.1 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Phospholip_A2_1 PF00068.19 CBY24939.1 - 4.1e-17 62.7 10.7 4.1e-17 62.7 10.7 2.0 1 1 1 2 2 2 1 Phospholipase A2 Toxin_2 PF00451.19 CBY24939.1 - 0.047 14.0 2.4 0.047 14.0 2.4 2.5 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 DUF2737 PF10930.8 CBY24940.1 - 0.018 14.6 0.6 0.033 13.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) UPF0061 PF02696.14 CBY24941.1 - 1.9e-97 327.0 0.0 2.5e-97 326.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family MyTH4 PF00784.17 CBY24941.1 - 0.043 14.3 0.1 0.098 13.2 0.1 1.6 1 0 0 1 1 1 0 MyTH4 domain RecR PF02132.15 CBY24942.1 - 0.17 11.5 1.5 7.7 6.2 0.1 2.6 2 0 0 2 2 2 0 RecR protein G8 PF10162.9 CBY24943.1 - 5.9e-19 68.3 0.0 1.1e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 G8 domain NosD PF05048.13 CBY24943.1 - 4.1e-07 29.5 0.9 9e-06 25.1 0.6 2.6 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 CBY24943.1 - 9.2e-05 22.3 8.1 9.2e-05 22.3 8.1 3.2 2 1 1 3 3 3 2 Right handed beta helix region DUF3786 PF12654.7 CBY24943.1 - 0.21 11.2 0.0 0.8 9.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) Sporozoite_P67 PF05642.11 CBY24943.1 - 0.52 8.3 10.4 0.81 7.7 10.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GLTP PF08718.11 CBY24944.1 - 3.3e-31 108.6 0.0 4.2e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ion_trans_2 PF07885.16 CBY24945.1 - 1.8e-20 72.7 12.4 2.8e-11 43.2 10.2 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CBY24945.1 - 0.0014 18.0 12.7 3.9 6.6 12.8 2.7 1 1 0 1 1 1 1 Ion transport protein MtrF PF09472.10 CBY24945.1 - 0.071 12.5 0.4 0.071 12.5 0.4 2.2 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TAP_C PF03943.13 CBY24945.1 - 0.17 11.5 0.3 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 TAP C-terminal domain CENP-M PF11111.8 CBY24946.1 - 0.021 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) ITI_HC_C PF06668.12 CBY24947.1 - 3.8e-05 23.4 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus DNA_pol3_theta PF06440.11 CBY24948.1 - 0.038 13.7 0.1 0.052 13.2 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase III, theta subunit Amidohydro_1 PF01979.20 CBY24949.1 - 4.8e-24 85.3 1.5 4.4e-11 42.7 0.4 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CBY24949.1 - 4e-12 46.4 1.8 8.2e-05 22.3 0.6 2.6 2 1 0 2 2 2 2 Amidohydrolase family Motile_Sperm PF00635.26 CBY24949.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain C2 PF00168.30 CBY24950.1 - 1.8e-19 69.9 0.0 1.1e-08 35.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain CsoSCA PF08936.10 CBY24950.1 - 0.063 11.9 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase 2OG-FeII_Oxy PF03171.20 CBY24951.1 - 5.1e-24 84.7 0.0 1.3e-23 83.4 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBY24951.1 - 3e-11 44.1 0.0 5.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal SpecificRecomb PF10136.9 CBY24952.1 - 0.1 10.9 1.4 0.24 9.7 1.4 1.7 1 0 0 1 1 1 0 Site-specific recombinase Zincin_2 PF10103.9 CBY24952.1 - 0.14 11.4 2.7 0.1 11.8 0.3 2.0 2 0 0 2 2 2 0 Zincin-like metallopeptidase SL4P PF17618.2 CBY24952.1 - 0.19 11.8 5.8 0.087 12.9 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized Strongylid L4 protein DUF932 PF06067.11 CBY24952.1 - 5.5 6.7 12.9 2.3 7.9 1.4 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF932) DUF1706 PF08020.11 CBY24953.1 - 0.015 15.2 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) FliT PF05400.13 CBY24953.1 - 0.1 13.4 0.4 0.17 12.7 0.4 1.3 1 0 0 1 1 1 0 Flagellar protein FliT bZIP_2 PF07716.15 CBY24953.1 - 0.37 10.9 2.6 1.8 8.7 0.3 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Gal-3-0_sulfotr PF06990.11 CBY24954.1 - 1.1e-21 77.2 2.2 2.6e-21 76.0 2.2 1.5 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Prefoldin_3 PF13758.6 CBY24954.1 - 0.093 12.8 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Prefoldin subunit Peptidase_M50 PF02163.22 CBY24955.1 - 3.2e-18 65.9 0.3 7.5e-18 64.7 0.3 1.6 1 1 0 1 1 1 1 Peptidase family M50 Peptidase_M50B PF13398.6 CBY24955.1 - 0.0019 17.9 1.8 0.0019 17.9 1.8 2.1 3 0 0 3 3 3 1 Peptidase M50B-like PDZ PF00595.24 CBY24955.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain APH PF01636.23 CBY24956.1 - 7.8e-44 150.4 0.0 1.4e-43 149.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 CBY24956.1 - 4.8e-31 108.0 3.0 9e-31 107.1 3.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY24956.1 - 4.9e-18 65.1 0.0 9.9e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HAD_2 PF13419.6 CBY24956.1 - 3.3e-17 63.2 1.1 6.8e-17 62.1 0.5 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acyl-CoA_dh_N PF02771.16 CBY24956.1 - 3.1e-15 56.8 0.0 1.5e-14 54.6 0.0 2.3 2 0 0 2 2 1 1 Acyl-CoA dehydrogenase, N-terminal domain Hydrolase PF00702.26 CBY24956.1 - 7.9e-09 36.1 0.1 1.8e-07 31.7 0.1 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acyl-CoA_dh_2 PF08028.11 CBY24956.1 - 5.4e-08 33.2 0.5 9.3e-08 32.4 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Hydrolase_like PF13242.6 CBY24956.1 - 3.5e-05 23.8 0.0 8.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Choline_kinase PF01633.20 CBY24956.1 - 0.00043 19.9 0.0 0.00088 18.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CBY24956.1 - 0.00097 18.5 0.0 0.0026 17.1 0.0 1.7 1 0 0 1 1 1 1 Ecdysteroid kinase Hydrolase_6 PF13344.6 CBY24956.1 - 0.02 15.0 0.1 0.096 12.8 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RIO1 PF01163.22 CBY24956.1 - 0.028 14.0 0.0 0.54 9.8 0.0 2.8 3 0 0 3 3 3 0 RIO1 family Acid_PPase PF12689.7 CBY24956.1 - 0.081 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase MFS_5 PF05631.14 CBY24957.1 - 2e-39 135.5 3.1 2.3e-39 135.3 3.1 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CBY24957.1 - 6.9e-09 35.1 8.2 2.4e-08 33.3 9.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY24957.1 - 0.002 17.1 1.5 0.0023 16.9 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY24958.1 - 0.00042 19.3 10.7 0.00051 19.1 10.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Thyroglobulin_1 PF00086.18 CBY24960.1 - 2.5e-05 23.8 0.1 4.5e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Tir_receptor_C PF07489.11 CBY24960.1 - 6.3 6.7 9.9 11 5.9 9.9 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus THDPS_N_2 PF14805.6 CBY24961.1 - 0.068 13.4 0.4 17 5.7 0.1 2.7 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal IL1_propep PF02394.16 CBY24961.1 - 3 8.8 10.7 0.36 11.8 0.5 3.3 2 1 1 3 3 3 0 Interleukin-1 propeptide Trypsin PF00089.26 CBY24962.1 - 3.7e-25 89.0 0.3 3.7e-25 89.0 0.3 1.8 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY24962.1 - 0.00056 20.8 0.1 0.00056 20.8 0.1 2.2 3 0 0 3 3 3 1 Trypsin-like peptidase domain DUF3439 PF11921.8 CBY24963.1 - 0.027 14.4 1.0 0.048 13.6 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PMP22_Claudin PF00822.20 CBY24964.1 - 9.3e-06 25.6 12.0 1.1e-05 25.3 11.6 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Cofilin_ADF PF00241.20 CBY24965.1 - 2.7e-22 78.8 0.5 3.9e-22 78.3 0.5 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Peptidase_C98 PF15499.6 CBY24965.1 - 0.0023 17.5 0.1 0.43 10.0 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase KMP11 PF03037.16 CBY24966.1 - 0.095 13.5 0.8 0.29 11.9 0.7 1.9 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 KIAA1430 PF13879.6 CBY24968.1 - 3.1 8.6 9.4 0.6 10.9 5.1 2.0 2 0 0 2 2 2 0 KIAA1430 homologue Pkinase PF00069.25 CBY24969.1 - 3.2e-42 144.7 0.2 4.5e-42 144.2 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24969.1 - 2.1e-31 109.1 0.0 2.9e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY24969.1 - 6.2e-11 42.1 0.0 1.8e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBY24969.1 - 0.00013 20.9 0.1 0.0058 15.4 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CBY24969.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY24969.1 - 0.02 14.8 0.0 0.23 11.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1524 PF07510.11 CBY24969.1 - 0.083 12.8 1.4 0.33 10.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1524) YrbL-PhoP_reg PF10707.9 CBY24969.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SurA_N_2 PF13623.6 CBY24970.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Cadherin_C_2 PF16492.5 CBY24970.1 - 0.12 13.1 0.0 0.16 12.7 0.0 1.4 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal TIG PF01833.24 CBY24971.1 - 2.9e-57 190.7 75.3 5.7e-13 48.8 0.8 12.8 11 1 1 12 12 12 9 IPT/TIG domain G8 PF10162.9 CBY24971.1 - 5e-43 146.1 0.0 1.5e-27 96.1 0.0 3.4 3 0 0 3 3 3 2 G8 domain Beta_helix PF13229.6 CBY24971.1 - 5.6e-06 26.3 38.7 1.2e-05 25.3 3.7 7.0 4 2 1 5 5 5 3 Right handed beta helix region GLEYA PF10528.9 CBY24971.1 - 8.3e-05 22.9 2.3 0.00024 21.4 0.5 3.1 2 0 0 2 2 2 1 GLEYA domain LRR_8 PF13855.6 CBY24971.1 - 0.014 15.1 11.8 0.0065 16.2 9.0 2.0 2 0 0 2 2 2 0 Leucine rich repeat Membrane_bind PF14564.6 CBY24971.1 - 0.094 13.2 1.0 18 5.8 0.0 3.7 3 0 0 3 3 3 0 Membrane binding LRR_4 PF12799.7 CBY24971.1 - 2.2 8.8 5.6 8.6 6.9 5.6 2.1 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) p450 PF00067.22 CBY24972.1 - 5.7e-47 160.5 0.2 7.5e-47 160.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Troponin PF00992.20 CBY24974.1 - 3e-24 85.8 33.7 1.5e-21 77.1 26.2 2.0 1 1 1 2 2 2 2 Troponin FXa_inhibition PF14670.6 CBY24975.1 - 6.9e-08 32.6 7.6 1.2e-07 31.9 7.6 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY24975.1 - 0.048 13.6 0.6 0.088 12.8 0.6 1.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF PF00008.27 CBY24975.1 - 1.4 9.2 7.1 3.5 8.0 7.1 1.6 1 0 0 1 1 1 0 EGF-like domain SPX PF03105.19 CBY24976.1 - 1.7e-06 28.2 3.9 2.4e-06 27.8 3.9 1.3 1 1 0 1 1 1 1 SPX domain EXS PF03124.14 CBY24977.1 - 1.9e-54 185.2 14.5 2.3e-54 185.0 14.5 1.0 1 0 0 1 1 1 1 EXS family DUF805 PF05656.14 CBY24977.1 - 0.077 13.4 3.6 0.18 12.2 3.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) RRM_1 PF00076.22 CBY24978.1 - 4.5e-27 93.7 1.2 5.3e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY24978.1 - 3e-10 40.1 0.5 0.00012 22.1 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CBY24978.1 - 4.5e-06 26.6 0.2 0.0091 16.0 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif DUF4651 PF15513.6 CBY24978.1 - 0.087 12.7 0.1 8.3 6.3 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4651) DUF1958 PF09211.10 CBY24978.1 - 0.13 12.6 0.3 0.94 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1958) HlyD_2 PF12700.7 CBY24980.1 - 0.89 8.2 18.5 0.11 11.3 14.2 1.5 2 0 0 2 2 2 0 HlyD family secretion protein DUF4337 PF14235.6 CBY24980.1 - 1.2 9.2 15.2 0.037 14.1 4.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Fungal_TACC PF12709.7 CBY24980.1 - 3.1 8.3 24.0 0.98 9.9 4.7 4.5 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 CBY24980.1 - 4.3 6.6 17.2 1.1e+02 2.0 17.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 CBY24980.1 - 4.6 7.0 37.4 3 7.7 24.9 3.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH LRR_8 PF13855.6 CBY24981.1 - 5.5e-40 135.0 35.8 7.7e-16 57.6 4.7 5.6 4 1 1 5 5 5 5 Leucine rich repeat I-set PF07679.16 CBY24981.1 - 9e-35 118.6 1.4 4.5e-16 58.7 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY24981.1 - 7.4e-30 103.4 1.3 2.1e-15 57.1 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.7 CBY24981.1 - 1.1e-26 92.5 40.2 5.1e-07 29.9 2.4 6.7 4 1 3 7 7 7 6 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 CBY24981.1 - 8.1e-21 74.2 0.8 1e-08 35.4 0.1 4.4 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 CBY24981.1 - 1.2e-17 63.8 0.9 1.4e-07 31.6 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain LRR_5 PF13306.6 CBY24981.1 - 1e-14 54.6 14.7 6.7e-10 39.0 1.6 3.6 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) V-set PF07686.17 CBY24981.1 - 1.2e-12 47.9 4.6 0.027 14.6 0.3 5.4 3 2 1 4 4 4 3 Immunoglobulin V-set domain LRR_9 PF14580.6 CBY24981.1 - 1.3e-10 41.1 18.7 8.6e-07 28.6 4.8 3.7 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 CBY24981.1 - 1.6e-09 37.0 30.6 0.12 13.0 0.3 10.8 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY24981.1 - 5.8e-07 29.1 29.3 0.41 10.8 0.1 9.9 9 0 0 9 9 9 2 Leucine Rich repeat Ig_4 PF16680.5 CBY24981.1 - 9.9e-05 22.5 0.0 0.15 12.3 0.0 2.9 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CBY24981.1 - 0.00024 21.4 0.4 0.17 12.3 0.0 3.3 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 CBY24981.1 - 0.001 19.1 0.6 1.4 9.1 0.0 3.1 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 CBY24981.1 - 0.0014 18.2 0.0 0.068 12.8 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain LRRCT PF01463.24 CBY24981.1 - 0.0045 17.4 0.1 0.025 15.1 0.1 2.4 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain C2-set PF05790.15 CBY24981.1 - 0.026 14.7 0.0 15 5.9 0.0 2.9 2 0 0 2 2 2 0 Immunoglobulin C2-set domain CBF_beta PF02312.17 CBY24983.1 - 4.4e-44 150.1 0.0 5.1e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Core binding factor beta subunit Pex14_N PF04695.13 CBY24983.1 - 0.48 11.1 10.9 0.71 10.5 10.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phospholip_A2_1 PF00068.19 CBY24985.1 - 1.9e-13 50.9 8.4 1.9e-13 50.9 8.4 1.5 2 0 0 2 2 2 1 Phospholipase A2 Pkinase_Tyr PF07714.17 CBY24987.1 - 2.7e-74 249.7 0.1 4.1e-74 249.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY24987.1 - 3.3e-40 138.1 0.0 6.9e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CBY24987.1 - 0.17 11.8 0.0 0.57 10.0 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Phospholip_A2_1 PF00068.19 CBY24988.1 - 8.2e-14 52.0 3.3 8.2e-14 52.0 3.3 1.7 2 0 0 2 2 2 1 Phospholipase A2 DUF5037 PF16440.5 CBY24989.1 - 0.18 11.2 0.8 0.45 10.0 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5037) Sushi PF00084.20 CBY24990.1 - 0.049 14.2 1.8 0.049 14.2 1.8 2.9 1 1 2 3 3 3 0 Sushi repeat (SCR repeat) Complex1_LYR_2 PF13233.6 CBY24991.1 - 4.2 8.2 6.7 4.5 8.1 3.5 2.6 2 1 0 2 2 2 0 Complex1_LYR-like Pkinase PF00069.25 CBY24992.1 - 3.3e-36 125.0 1.6 5.1e-36 124.4 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY24992.1 - 5.5e-19 68.4 0.0 2.2e-18 66.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_MLP1_2 PF07926.12 CBY24992.1 - 1.9e-06 28.0 24.8 1.9e-06 28.0 24.8 3.2 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 CBY24992.1 - 0.00095 19.7 23.1 0.00095 19.7 23.1 2.5 1 1 1 2 2 2 1 Fez1 T2SSF PF00482.23 CBY24992.1 - 0.12 12.4 2.3 1.1 9.3 0.8 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F HALZ PF02183.18 CBY24992.1 - 0.28 11.4 26.1 0.15 12.3 2.0 5.1 4 1 0 5 5 5 0 Homeobox associated leucine zipper HAUS-augmin3 PF14932.6 CBY24992.1 - 0.61 9.6 27.2 1.3 8.6 4.7 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF812 PF05667.11 CBY24992.1 - 0.96 8.3 30.4 1.4 7.7 30.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TLE_N PF03920.15 CBY24992.1 - 4 7.5 13.6 3.8 7.6 1.0 2.9 2 1 1 3 3 3 0 Groucho/TLE N-terminal Q-rich domain DUF465 PF04325.13 CBY24992.1 - 4.2 7.5 24.0 0.8 9.8 1.2 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF465) Fib_alpha PF08702.10 CBY24992.1 - 4.6 7.4 28.8 9.5 6.4 6.7 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 CBY24992.1 - 8.2 6.8 29.2 2.9 8.2 5.6 3.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Occludin_ELL PF07303.13 CBY24992.1 - 9.9 7.0 25.7 2.9 8.7 9.8 3.5 2 1 1 3 3 3 0 Occludin homology domain Xan_ur_permease PF00860.20 CBY24994.1 - 5.4e-83 278.8 21.5 5.4e-83 278.8 21.5 1.4 2 0 0 2 2 2 1 Permease family EGF_CA PF07645.15 CBY24995.1 - 0.00091 19.4 3.5 0.00091 19.4 3.5 1.9 2 1 0 2 2 2 1 Calcium-binding EGF domain PorB PF11565.8 CBY24995.1 - 0.09 13.2 0.0 0.94 9.9 0.0 2.1 2 0 0 2 2 2 0 Alpha helical Porin B Rhomboid PF01694.22 CBY24996.1 - 9.7e-16 58.1 0.9 1.5e-15 57.5 0.9 1.3 1 0 0 1 1 1 1 Rhomboid family HEAT_EZ PF13513.6 CBY24997.1 - 1.1e-09 38.6 20.8 5e-05 23.7 0.2 8.7 10 2 1 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.6 CBY24997.1 - 2.3e-05 24.7 3.1 0.065 13.6 0.1 5.9 4 3 2 6 6 6 1 HEAT repeats HEAT PF02985.22 CBY24997.1 - 3.8e-05 23.6 10.2 0.35 11.2 0.0 6.9 7 0 0 7 7 7 2 HEAT repeat Cnd3 PF12719.7 CBY24997.1 - 0.00015 21.1 0.6 0.015 14.5 0.0 4.0 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain MIP PF00230.20 CBY24997.1 - 0.0055 16.4 0.9 0.093 12.4 0.0 2.3 2 0 0 2 2 2 1 Major intrinsic protein RTP1_C1 PF10363.9 CBY24997.1 - 0.031 14.4 0.0 9.5 6.4 0.0 4.5 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Importin_rep_4 PF18808.1 CBY24997.1 - 0.19 12.0 6.2 8 6.8 0.0 5.4 6 0 0 6 6 6 0 Importin repeat DUF4704 PF15787.5 CBY24997.1 - 0.49 9.6 5.3 0.33 10.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4704) TFIIA PF03153.13 CBY24998.1 - 5.9e-49 168.2 25.4 8.4e-34 118.3 24.9 2.5 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CBY24998.1 - 4 5.6 15.3 4.8 5.3 15.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_C1 PF00112.23 CBY24999.1 - 3.4e-78 262.7 5.3 5e-78 262.1 5.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY24999.1 - 1.1e-14 54.6 1.3 1.8e-14 53.9 1.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY24999.1 - 0.015 14.1 2.2 1.9 7.2 0.4 2.3 2 0 0 2 2 2 0 Peptidase C1-like family Cg6151-P PF10233.9 CBY25000.1 - 5.4e-16 58.9 5.7 6.6e-16 58.6 5.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2981 PF11200.8 CBY25000.1 - 0.043 13.6 0.6 0.063 13.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DEAD PF00270.29 CBY25002.1 - 1.5e-48 164.9 0.0 3.1e-48 163.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY25002.1 - 4.1e-32 110.8 0.0 1.1e-31 109.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY25002.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 CBY25002.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Vault PF01505.18 CBY25003.1 - 1.9e-58 194.4 0.5 1.4e-16 60.3 0.0 5.0 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 CBY25003.1 - 4.8e-48 162.1 0.5 1.2e-47 160.8 0.5 1.7 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 CBY25003.1 - 2.5e-31 107.8 0.2 3.7e-21 75.3 0.2 2.8 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 CBY25003.1 - 3.8e-30 103.7 2.4 4.4e-27 93.9 0.1 3.3 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 CBY25003.1 - 5.1e-29 100.1 0.1 5.6e-28 96.8 0.2 2.7 2 0 0 2 2 2 1 Major Vault Protein repeat domain DUF3601 PF12208.8 CBY25003.1 - 0.0022 18.0 0.0 1.4 9.0 0.0 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3601) ECSIT_C PF14784.6 CBY25003.1 - 0.11 12.9 0.5 0.37 11.1 0.5 1.9 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein ERM PF00769.19 CBY25003.1 - 1.2 8.9 25.3 2.3 8.0 25.3 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family RhoGEF PF00621.20 CBY25004.1 - 1.9e-32 112.9 2.3 1.9e-32 112.9 2.3 2.0 2 0 0 2 2 2 1 RhoGEF domain BRCT PF00533.26 CBY25004.1 - 1.3e-09 38.3 0.0 0.00052 20.3 0.0 3.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBY25004.1 - 0.0002 21.7 0.0 0.0036 17.7 0.0 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CBY25004.1 - 0.0084 16.0 0.0 0.89 9.6 0.0 2.7 2 0 0 2 2 2 1 twin BRCT domain PH_10 PF15411.6 CBY25004.1 - 0.088 13.1 0.7 0.26 11.5 0.7 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain CEL_III_C PF18054.1 CBY25004.1 - 0.09 12.8 0.1 0.52 10.4 0.0 2.3 2 0 0 2 2 2 0 CEL-III C-terminal SAPS PF04499.15 CBY25006.1 - 3.9e-13 49.0 31.2 3.9e-12 45.7 0.5 3.9 3 1 0 3 3 3 3 SIT4 phosphatase-associated protein DnaJ PF00226.31 CBY25007.1 - 2.2e-16 59.7 0.1 6.5e-16 58.2 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain PH_4 PF15404.6 CBY25007.1 - 1.4 8.7 8.1 0.17 11.7 2.5 2.1 2 1 0 2 2 2 0 Pleckstrin homology domain Peptidase_M24 PF00557.24 CBY25008.1 - 1.3e-34 119.8 0.0 1.8e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CBY25008.1 - 5.3e-32 111.1 0.0 1.1e-31 110.2 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CBY25008.1 - 5.8e-14 51.9 0.4 5.8e-14 51.9 0.4 1.8 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CBY25008.1 - 5.6e-06 27.1 0.0 4.7e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain SGT1 PF07093.11 CBY25008.1 - 0.028 12.9 0.0 0.046 12.2 0.0 1.2 1 0 0 1 1 1 0 SGT1 protein PBD PF00786.28 CBY25009.1 - 3e-07 30.7 1.2 6.2e-07 29.7 0.1 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain Gal-3-0_sulfotr PF06990.11 CBY25011.1 - 1.6e-44 152.4 0.4 6.1e-43 147.2 0.4 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY25011.1 - 4.7e-06 26.7 6.9 4.9e-06 26.6 0.2 3.3 3 1 0 3 3 3 1 Sulfotransferase family FERM_N PF09379.10 CBY25011.1 - 0.015 15.2 0.4 0.083 12.8 0.0 2.3 2 0 0 2 2 2 0 FERM N-terminal domain EGF_2 PF07974.13 CBY25012.1 - 3.6e-10 40.0 199.6 5.5e-05 23.5 13.3 12.8 13 1 1 14 14 14 7 EGF-like domain EGF PF00008.27 CBY25012.1 - 0.00072 19.8 35.3 0.0032 17.7 6.7 11.6 12 0 0 12 12 12 7 EGF-like domain NOG1_N PF17835.1 CBY25014.1 - 7e-51 172.4 0.4 7e-51 172.4 0.4 2.0 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 CBY25014.1 - 2.1e-24 85.0 0.1 4e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 CBY25014.1 - 2.4e-21 75.5 2.3 5.5e-21 74.3 2.3 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 CBY25014.1 - 1.5e-19 70.2 0.0 3.5e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY25014.1 - 1.7e-12 47.1 0.0 2.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBY25014.1 - 2.9e-05 24.0 0.0 0.046 13.6 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CBY25014.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AIG1 PF04548.16 CBY25014.1 - 0.0085 15.4 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 CBY25014.1 - 0.017 15.5 0.0 0.058 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 CBY25014.1 - 0.024 14.7 0.1 9.2 6.3 0.0 2.7 1 1 1 2 2 2 0 Dynamin family Phosphorylase PF00343.20 CBY25015.1 - 0 1109.5 0.0 0 1109.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase GldM_N PF12081.8 CBY25015.1 - 0.0031 17.6 0.1 0.0067 16.6 0.1 1.5 1 0 0 1 1 1 1 GldM N-terminal domain DUF3417 PF11897.8 CBY25015.1 - 0.19 12.2 2.3 22 5.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) LUC7 PF03194.15 CBY25016.1 - 2.8e-87 292.5 9.3 2.8e-87 292.5 9.3 2.1 2 1 0 2 2 2 1 LUC7 N_terminus AKAP95 PF04988.12 CBY25016.1 - 0.062 13.5 3.6 0.066 13.4 0.2 2.4 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Nucleoporin_FG PF13634.6 CBY25017.1 - 8.1e-20 71.5 86.7 1.8e-08 35.1 16.5 10.5 3 2 6 9 9 9 5 Nucleoporin FG repeat region ANAPC4_WD40 PF12894.7 CBY25018.1 - 0.012 15.9 0.0 0.073 13.4 0.0 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 CBY25019.1 - 6.1e-17 61.6 28.1 6.1e-17 61.6 28.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily EMP70 PF02990.16 CBY25019.1 - 1.1 7.9 12.7 0.33 9.5 9.5 1.7 1 1 0 1 1 1 0 Endomembrane protein 70 IFT46_B_C PF12317.8 CBY25020.1 - 1.2e-68 231.1 0.0 1.6e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Ank_2 PF12796.7 CBY25021.1 - 4.1e-40 136.2 8.3 2.4e-13 50.5 0.1 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY25021.1 - 2e-34 117.2 10.3 3.4e-10 40.0 0.1 7.2 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 CBY25021.1 - 2.4e-34 116.3 8.8 3.2e-06 27.3 0.1 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 CBY25021.1 - 2.2e-30 104.6 12.8 1.6e-06 28.6 0.1 7.9 2 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY25021.1 - 2.5e-30 101.1 8.0 0.0011 19.3 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Death PF00531.22 CBY25021.1 - 1.5e-06 28.3 0.5 3.8e-06 27.0 0.5 1.7 1 0 0 1 1 1 1 Death domain SbsC_C PF18058.1 CBY25022.1 - 0.068 13.4 0.2 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 SbsC C-terminal domain DUF816 PF05674.12 CBY25023.1 - 0.042 13.8 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) DUF1943 PF09172.11 CBY25025.1 - 5.3 6.2 8.8 0.22 10.7 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) RNA_pol_Rpb6 PF01192.22 CBY25026.1 - 0.059 13.3 0.1 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb6 Cu_bind_like PF02298.17 CBY25026.1 - 0.16 12.0 0.1 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Plastocyanin-like domain DUF1690 PF07956.11 CBY25026.1 - 1 9.7 8.8 0.48 10.8 2.5 3.2 2 1 0 3 3 3 0 Protein of Unknown function (DUF1690) ITI_HC_C PF06668.12 CBY25027.1 - 0.00014 21.6 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus EGF_3 PF12947.7 CBY25027.1 - 6.6 7.0 80.2 0.11 12.7 5.3 6.3 5 1 0 5 5 5 0 EGF domain EGF_CA PF07645.15 CBY25027.1 - 8 6.8 103.7 0.25 11.6 11.4 6.5 6 0 0 6 6 6 0 Calcium-binding EGF domain zf-C3HC4_3 PF13920.6 CBY25028.1 - 5.7e-05 22.9 11.2 5.7e-05 22.9 11.2 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 CBY25028.1 - 0.0036 18.0 0.9 0.0036 18.0 0.9 6.7 9 1 0 9 9 9 1 C2H2-type zinc finger JmjC PF02373.22 CBY25028.1 - 0.22 12.0 1.8 0.42 11.1 0.2 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase zf-C3HC4_3 PF13920.6 CBY25029.1 - 1.2e-06 28.2 4.0 1.9e-06 27.6 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY25029.1 - 0.065 13.1 4.8 0.1 12.4 4.8 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Methyltr_RsmB-F PF01189.17 CBY25030.1 - 6.3e-26 91.3 0.0 9.7e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 CBY25030.1 - 0.0092 15.8 0.1 0.17 11.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY25030.1 - 0.038 13.3 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CBY25030.1 - 0.042 14.6 0.0 0.7 10.6 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 CBY25030.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Met_10 PF02475.16 CBY25030.1 - 0.064 13.0 0.0 0.4 10.4 0.0 2.3 3 0 0 3 3 3 0 Met-10+ like-protein ArfGap PF01412.18 CBY25031.1 - 3.4e-38 130.3 0.1 3.4e-38 130.3 0.1 2.7 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 CBY25031.1 - 2e-18 67.0 10.5 2e-18 67.0 10.5 1.9 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 CBY25031.1 - 3.8e-12 46.7 0.3 9.6e-12 45.3 0.3 1.8 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.6 CBY25031.1 - 0.00067 19.9 0.1 0.003 17.9 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY25031.1 - 0.00075 20.0 0.0 0.007 16.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY25031.1 - 0.0038 17.6 0.0 1.6 9.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat UvrC_HhH_N PF08459.11 CBY25031.1 - 0.0048 16.8 0.1 0.014 15.3 0.1 1.8 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal PH_13 PF16652.5 CBY25031.1 - 0.021 14.6 0.6 0.095 12.5 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Ank_4 PF13637.6 CBY25031.1 - 0.12 13.0 0.0 0.68 10.6 0.0 2.2 1 1 0 2 2 2 0 Ankyrin repeats (many copies) PH_11 PF15413.6 CBY25031.1 - 1.8 9.0 6.2 52 4.3 6.2 3.0 1 1 0 1 1 1 0 Pleckstrin homology domain RMI1_N PF08585.12 CBY25031.1 - 6.2 6.5 10.7 0.18 11.5 1.0 2.8 3 1 0 3 3 3 0 RecQ mediated genome instability protein MRP_L53 PF10780.9 CBY25032.1 - 0.03 14.5 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 ADK PF00406.22 CBY25033.1 - 1.3e-55 187.7 0.0 1.5e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBY25033.1 - 9.9e-24 84.3 0.1 3.9e-23 82.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CBY25033.1 - 9e-16 57.6 0.0 2.3e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CBY25033.1 - 2.1e-05 24.7 0.0 3.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY25033.1 - 0.0014 19.1 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 CBY25033.1 - 0.013 15.8 0.1 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 CBY25033.1 - 0.031 14.0 0.0 0.25 11.0 0.0 2.0 1 1 1 2 2 2 0 Cytidylate kinase AAA PF00004.29 CBY25033.1 - 0.17 12.3 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CBY25033.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ribosomal_L1 PF00687.21 CBY25034.1 - 0.002 17.9 0.6 0.016 14.9 0.6 2.0 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family CNDH2_N PF06278.11 CBY25035.1 - 0.017 15.4 0.2 0.017 15.3 0.2 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Toluene_X PF03349.16 CBY25036.1 - 0.027 13.0 3.2 0.04 12.5 0.3 1.9 1 1 1 2 2 2 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) TSP_1 PF00090.19 CBY25036.1 - 0.8 10.0 12.7 3.1 8.1 0.1 2.7 2 1 0 2 2 2 0 Thrombospondin type 1 domain TSP_1 PF00090.19 CBY25037.1 - 2.6e-07 30.7 2.1 2.6e-07 30.7 2.1 3.7 2 1 1 3 3 3 2 Thrombospondin type 1 domain Cnd1 PF12717.7 CBY25038.1 - 1.1e-05 25.6 0.1 9e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBY25039.1 - 7.4e-06 25.8 3.5 0.46 10.9 0.1 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 CBY25039.1 - 0.0033 17.5 5.7 1.5 8.8 0.0 3.9 2 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Gcn1_N PF12074.8 CBY25039.1 - 0.072 12.4 0.1 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal zf-C2H2_6 PF13912.6 CBY25042.1 - 0.096 12.7 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger SNAP PF14938.6 CBY25043.1 - 8.8e-20 71.3 7.2 1.2e-19 70.9 7.2 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CBY25043.1 - 0.0014 18.9 9.9 0.18 12.1 0.2 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY25043.1 - 0.017 15.9 9.9 2.6 9.1 0.1 4.9 3 2 2 6 6 6 0 Tetratricopeptide repeat Clathrin PF00637.20 CBY25043.1 - 0.12 12.3 1.2 6.2 6.7 0.3 3.1 2 1 1 3 3 3 0 Region in Clathrin and VPS Vta1_C PF18097.1 CBY25043.1 - 0.37 10.5 3.2 0.58 9.9 0.8 2.6 3 0 0 3 3 3 0 Vta1 C-terminal domain TPR_7 PF13176.6 CBY25043.1 - 0.62 10.2 4.7 3.7 7.8 0.1 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY25043.1 - 9.8 6.2 9.3 69 3.5 0.3 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat MORN PF02493.20 CBY25045.1 - 3.5e-24 83.2 46.0 4.7e-07 29.3 0.6 6.7 7 0 0 7 7 7 6 MORN repeat WASH-7_mid PF14744.6 CBY25046.1 - 0.019 14.1 0.9 1.3 8.1 0.1 2.0 2 0 0 2 2 2 0 WASH complex subunit 7 DNA_topoisoIV PF00521.20 CBY25046.1 - 0.033 13.1 1.0 0.037 12.9 1.0 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Chromo PF00385.24 CBY25047.1 - 2.6e-12 46.4 1.3 6.5e-12 45.2 1.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ncstrn_small PF18266.1 CBY25048.1 - 3.4e-37 128.0 0.0 5.6e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 CBY25048.1 - 5e-13 49.1 0.6 1.6e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Nicastrin Adap_comp_sub PF00928.21 CBY25049.1 - 1.7e-65 221.0 0.0 2.3e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBY25049.1 - 2.3e-07 30.8 0.6 3.8e-07 30.1 0.6 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NRIP1_repr_3 PF15689.5 CBY25049.1 - 0.14 12.4 0.0 5.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 CLASP_N PF12348.8 CBY25050.1 - 2.6e-18 66.4 18.4 1.2e-05 25.0 0.7 6.2 7 0 0 7 7 7 4 CLASP N terminal HEAT PF02985.22 CBY25050.1 - 1.3e-14 53.1 1.2 0.012 15.8 0.0 9.4 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 CBY25050.1 - 8.1e-08 32.6 0.5 32 5.0 0.0 8.4 9 2 1 10 10 10 0 HEAT repeats RTP1_C1 PF10363.9 CBY25050.1 - 1.3e-05 25.3 2.0 0.0088 16.2 0.0 5.9 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 TAN PF11640.8 CBY25050.1 - 2.5e-05 24.5 7.7 0.082 13.0 0.0 6.1 6 1 1 7 7 7 2 Telomere-length maintenance and DNA damage repair Vac14_Fab1_bd PF12755.7 CBY25050.1 - 3.8e-05 24.2 5.4 4 8.1 0.0 6.7 7 1 0 7 7 7 1 Vacuolar 14 Fab1-binding region Utp13 PF08625.11 CBY25050.1 - 0.013 15.4 5.6 2.8 7.8 0.7 4.2 3 1 1 4 4 4 0 Utp13 specific WD40 associated domain HEAT_EZ PF13513.6 CBY25050.1 - 0.015 15.8 0.2 24 5.6 0.0 5.3 5 0 0 5 5 5 0 HEAT-like repeat Vta1_C PF18097.1 CBY25050.1 - 0.086 12.6 0.8 0.34 10.6 0.0 2.4 2 0 0 2 2 2 0 Vta1 C-terminal domain CUB PF00431.20 CBY25054.1 - 1.2e-08 35.3 0.1 2.5e-07 31.0 0.1 2.4 1 1 1 2 2 2 1 CUB domain Tektin PF03148.14 CBY25055.1 - 3.1e-110 368.5 45.6 3.5e-110 368.4 45.6 1.0 1 0 0 1 1 1 1 Tektin family DUF507 PF04368.13 CBY25055.1 - 0.0059 16.6 7.5 0.0059 16.6 7.5 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF507) CHASE7 PF17151.4 CBY25055.1 - 0.04 13.5 1.6 0.17 11.5 0.6 2.5 1 1 1 2 2 2 0 Periplasmic sensor domain TPR_22 PF18833.1 CBY25055.1 - 0.078 13.1 2.7 0.088 12.9 0.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1664 PF07889.12 CBY25055.1 - 0.13 12.3 26.8 1.5 8.9 5.6 4.5 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 CBY25055.1 - 0.46 10.8 22.1 2.4 8.5 0.4 5.1 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CBY25055.1 - 0.68 10.0 16.7 0.027 14.5 5.1 3.3 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5099 PF17025.5 CBY25055.1 - 0.78 10.2 6.9 3.6 8.0 0.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5099) SRP54_N PF02881.19 CBY25055.1 - 9.9 6.5 12.6 1.2 9.4 0.9 4.2 2 1 2 4 4 4 0 SRP54-type protein, helical bundle domain zf-met PF12874.7 CBY25056.1 - 2.4e-10 40.4 3.1 3.1e-05 24.2 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY25056.1 - 0.0074 16.6 3.8 0.85 10.0 0.2 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY25056.1 - 0.069 13.5 2.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 CBY25056.1 - 1.2 9.0 7.6 0.73 9.6 0.1 2.7 2 1 0 2 2 2 0 U1 zinc finger zf_C2H2_6 PF18450.1 CBY25056.1 - 5.1 6.9 5.9 36 4.2 2.0 2.5 2 0 0 2 2 2 0 Zinc Finger domain zf-C2H2 PF00096.26 CBY25056.1 - 6.1 7.5 6.4 35 5.1 1.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Trypsin PF00089.26 CBY25057.1 - 1.6e-50 172.0 0.2 1.8e-50 171.8 0.2 1.0 1 0 0 1 1 1 1 Trypsin AhpC-TSA PF00578.21 CBY25059.1 - 1.4e-34 118.6 0.0 1.9e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY25059.1 - 4.7e-15 55.6 0.0 5.7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBY25059.1 - 2.1e-13 49.8 0.1 3.9e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CBY25059.1 - 0.084 12.8 0.4 0.21 11.5 0.4 1.6 1 0 0 1 1 1 0 SCO1/SenC Integrin_alpha2 PF08441.12 CBY25061.1 - 5.2e-64 216.8 3.3 8.5e-64 216.1 3.3 1.3 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CBY25061.1 - 1.2e-18 66.9 5.9 4.6e-05 23.4 0.1 3.9 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 CBY25061.1 - 9.4e-16 58.2 4.5 5e-11 43.0 0.4 3.0 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 CBY25061.1 - 0.097 12.7 0.2 2.2 8.3 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Acyltransferase PF01553.21 CBY25062.1 - 1.7e-24 86.0 0.1 4.5e-24 84.6 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase TraG-D_C PF12696.7 CBY25063.1 - 0.38 10.8 6.2 0.97 9.4 6.2 2.0 1 1 0 1 1 1 0 TraM recognition site of TraD and TraG Noelin-1 PF12308.8 CBY25063.1 - 0.49 10.4 6.2 0.078 13.0 1.5 2.0 2 1 0 2 2 2 0 Neurogenesis glycoprotein zf-C4H2 PF10146.9 CBY25063.1 - 2.1 8.6 18.7 3.6 7.8 18.7 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein Dus PF01207.17 CBY25064.1 - 4.2e-56 190.3 0.0 4.8e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CBY25064.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 CBY25064.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.6 CBY25064.1 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase TMP-TENI PF02581.17 CBY25064.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase DUF561 PF04481.12 CBY25064.1 - 0.079 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) AROS PF15684.5 CBY25065.1 - 0.092 13.3 23.1 0.61 10.6 23.1 1.9 1 1 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 DNA_topoisoIV PF00521.20 CBY25067.1 - 2.9e-116 388.8 0.5 2.9e-116 388.8 0.5 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CBY25067.1 - 1.1e-39 135.7 4.4 1.1e-39 135.6 1.6 2.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CBY25067.1 - 3.1e-27 95.2 2.6 7.5e-27 93.9 2.6 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CBY25067.1 - 3.2e-13 50.2 0.1 1.3e-12 48.2 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CBY25067.1 - 9.4e-08 32.2 0.0 5.9e-07 29.7 0.0 2.5 1 0 0 1 1 1 1 Toprim domain DDE_Tnp_1 PF01609.21 CBY25067.1 - 0.013 15.2 1.1 0.041 13.5 0.7 2.0 2 0 0 2 2 2 0 Transposase DDE domain ABC_tran_CTD PF16326.5 CBY25067.1 - 3.2 8.1 8.8 0.45 10.8 2.4 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain TUDOR PF00567.24 CBY25069.1 - 6.9e-11 42.2 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Syntaxin_2 PF14523.6 CBY25070.1 - 1.2e-13 51.3 9.0 2.5e-13 50.3 9.0 1.5 1 0 0 1 1 1 1 Syntaxin-like protein FliS_cochap PF16522.5 CBY25070.1 - 0.0025 17.8 7.2 0.012 15.5 2.8 2.4 1 1 0 2 2 2 2 Flagellar FLiS export co-chaperone, HP1076 CCDC-167 PF15188.6 CBY25070.1 - 0.0034 17.7 1.2 0.0034 17.7 1.2 1.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 Syntaxin PF00804.25 CBY25070.1 - 2.7 7.6 14.4 2.8 7.6 2.1 2.2 1 1 0 2 2 2 0 Syntaxin LLGL PF08366.13 CBY25071.1 - 2.2e-05 24.7 0.0 4.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 LLGL2 WD40 PF00400.32 CBY25071.1 - 0.00034 21.4 0.1 0.0014 19.4 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY25071.1 - 0.00082 19.6 0.1 0.0015 18.7 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 CBY25071.1 - 0.064 11.9 0.1 4.7 5.7 0.0 2.2 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin AdoHcyase PF05221.17 CBY25072.1 - 4.3e-76 255.9 0.1 5e-76 255.7 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase DHHC PF01529.20 CBY25074.1 - 0.51 10.5 10.8 6.4 6.9 7.8 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Tetraspanin PF00335.20 CBY25075.1 - 8.8e-20 71.4 0.4 4.2e-14 52.8 0.1 2.1 2 0 0 2 2 2 2 Tetraspanin family MdcG PF10620.9 CBY25075.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG YHYH PF14240.6 CBY25076.1 - 4.1e-16 59.5 0.2 1.3e-10 41.5 0.0 2.8 2 1 1 3 3 3 2 YHYH protein CoA_transf_3 PF02515.17 CBY25077.1 - 6.2e-109 364.5 0.0 7e-109 364.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III LSM PF01423.22 CBY25078.1 - 4.2e-21 74.4 0.0 4.9e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY25078.1 - 0.009 16.1 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain HSF_DNA-bind PF00447.17 CBY25079.1 - 4.1e-29 101.1 0.6 4.1e-29 101.1 0.6 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding DUF2353 PF09789.9 CBY25079.1 - 0.051 12.9 9.2 0.15 11.4 9.2 1.7 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) ADIP PF11559.8 CBY25079.1 - 0.085 12.9 5.9 0.064 13.4 3.6 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPP_enzyme_N PF02776.18 CBY25080.1 - 1.3e-46 158.3 0.2 3.5e-46 156.9 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CBY25080.1 - 1.4e-22 80.1 0.0 1.7e-21 76.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CBY25080.1 - 1.3e-12 47.6 0.1 5.2e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain UNC-50 PF05216.13 CBY25081.1 - 2.7e-71 239.6 14.9 3.1e-71 239.5 14.9 1.0 1 0 0 1 1 1 1 UNC-50 family DUF2752 PF10825.8 CBY25081.1 - 0.026 14.6 0.5 0.026 14.6 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) RRM_1 PF00076.22 CBY25082.1 - 7e-07 29.0 0.1 9.1e-05 22.2 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBY25084.1 - 2.4e-34 117.0 1.8 7.7e-16 57.7 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY25084.1 - 0.001 19.2 0.1 0.46 10.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 CBY25084.1 - 0.0011 18.8 0.3 0.67 9.7 0.0 3.2 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain GlcNAc-1_reg PF18440.1 CBY25084.1 - 1.2 9.4 5.2 0.85 9.9 0.4 2.9 3 1 0 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain CDC45 PF02724.14 CBY25084.1 - 3.4 5.8 26.0 0.0038 15.6 12.2 2.0 2 0 0 2 2 2 0 CDC45-like protein PID PF00640.23 CBY25085.1 - 3.6e-22 78.9 0.5 1.7e-21 76.7 0.2 2.2 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 CBY25085.1 - 0.00023 21.3 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 CBY25085.1 - 0.027 14.3 0.3 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) PsaN PF05479.11 CBY25085.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Tmpp129 PF10272.9 CBY25086.1 - 9.3e-30 104.1 8.8 5.8e-20 71.9 10.9 3.0 1 1 1 2 2 2 2 Putative transmembrane protein precursor Kinesin PF00225.23 CBY25087.1 - 2.5e-104 348.8 0.2 2.5e-104 348.8 0.2 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY25087.1 - 6.8e-28 97.5 0.0 3.2e-27 95.3 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding ADIP PF11559.8 CBY25087.1 - 0.00035 20.7 4.2 0.00035 20.7 4.2 4.9 3 1 2 5 5 5 1 Afadin- and alpha -actinin-Binding Herpes_UL33 PF03581.13 CBY25087.1 - 0.14 12.5 0.1 0.47 10.9 0.1 1.9 1 0 0 1 1 1 0 Herpesvirus UL33-like protein CT_C_D PF02682.16 CBY25087.1 - 8.2 6.1 9.1 3.7 7.2 2.4 2.8 2 1 1 3 3 3 0 Carboxyltransferase domain, subdomain C and D Sulfatase_C PF14707.6 CBY25087.1 - 9.1 7.0 8.2 1.4 9.7 0.4 3.0 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase BAR_3_WASP_bdg PF10456.9 CBY25088.1 - 3e-34 118.5 2.5 4.2e-34 118.0 2.5 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 CBY25088.1 - 7.4e-20 71.0 0.0 1.5e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 CBY25088.1 - 8.1e-10 38.4 0.1 1.5e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY25088.1 - 5.2e-09 35.6 0.0 9.8e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY25088.1 - 1.2e-07 31.3 0.1 2.3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 CBY25088.1 - 2.3e-05 24.1 1.2 2.3e-05 24.1 1.2 2.2 1 1 0 2 2 2 1 Vps5 C terminal like FAM92 PF06730.11 CBY25088.1 - 0.0099 15.3 2.3 0.028 13.8 0.5 2.0 2 0 0 2 2 2 1 FAM92 protein hSH3 PF14603.6 CBY25088.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Helically-extended SH3 domain DUF1451 PF07295.11 CBY25088.1 - 0.11 12.6 1.7 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain Syndecan PF01034.20 CBY25089.1 - 0.063 13.2 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain GAPT PF11770.8 CBY25089.1 - 0.085 12.7 0.2 0.11 12.3 0.2 1.4 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) CD34_antigen PF06365.12 CBY25089.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family zf-CCCH PF00642.24 CBY25091.1 - 2.1e-18 65.7 12.6 9.6e-11 41.3 3.2 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY25091.1 - 2.1e-07 30.7 16.3 0.00082 19.3 2.8 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CBY25091.1 - 9.5e-07 28.5 11.9 0.00047 19.9 1.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CBY25091.1 - 0.013 16.0 10.2 0.038 14.5 1.6 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CBY25091.1 - 0.018 15.7 16.8 0.038 14.7 1.7 2.9 2 1 1 3 3 3 0 Torus domain oligo_HPY PF08352.12 CBY25091.1 - 2.1 9.0 6.3 7 7.3 0.3 2.5 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCHH PF10283.9 CBY25091.1 - 7.3 6.7 8.8 15 5.6 0.4 2.6 2 0 0 2 2 2 0 PBZ domain PfkB PF00294.24 CBY25092.1 - 5.6e-63 213.0 0.2 7e-63 212.7 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CBY25092.1 - 0.00025 20.5 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PP2C PF00481.21 CBY25095.1 - 2.2e-33 116.0 0.1 7.1e-33 114.3 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY25095.1 - 2.1e-10 40.6 0.0 3.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C RSF PF14876.6 CBY25096.1 - 0.0017 17.4 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator Glyco_hydro_1 PF00232.18 CBY25097.1 - 0 1176.4 18.5 6.5e-129 430.3 2.5 4.2 4 1 0 4 4 4 3 Glycosyl hydrolase family 1 VSP PF03302.13 CBY25097.1 - 0.026 13.4 0.1 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf_CCCH_5 PF18384.1 CBY25099.1 - 2.7e-21 75.4 13.4 2.7e-21 75.4 13.4 3.1 2 0 0 2 2 2 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 CBY25099.1 - 8.3e-06 25.6 3.1 8.3e-06 25.6 3.1 5.1 7 0 0 7 7 7 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Corona_NS2 PF04753.12 CBY25100.1 - 0.11 13.0 0.1 0.42 11.2 0.1 1.9 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 DUF1104 PF06518.11 CBY25100.1 - 5.1 7.5 10.9 1.2 9.5 6.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) zf-rbx1 PF12678.7 CBY25103.1 - 2.6e-18 66.0 14.4 4.3e-18 65.3 14.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY25103.1 - 3.7e-15 55.8 15.4 5.2e-15 55.3 15.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBY25103.1 - 0.0016 18.7 22.2 0.036 14.4 22.2 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY25103.1 - 0.028 14.3 14.2 0.087 12.7 14.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY25103.1 - 0.15 11.9 17.2 1.8 8.5 17.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY25103.1 - 6.1 6.8 17.3 0.35 10.8 9.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HEAT_2 PF13646.6 CBY25104.1 - 1.8e-11 44.3 0.0 0.026 14.9 0.0 4.4 1 1 1 3 3 3 3 HEAT repeats Arm PF00514.23 CBY25104.1 - 2.7e-08 33.6 0.2 0.0085 16.1 0.1 5.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBY25104.1 - 4.5e-07 29.6 7.2 7.3 7.1 0.3 6.9 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 CBY25104.1 - 7.1e-06 24.9 3.5 2.7e-05 22.9 3.5 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBY25104.1 - 0.00049 20.2 5.2 0.067 13.2 0.2 3.1 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 CBY25104.1 - 0.0026 16.9 3.7 0.49 9.4 0.1 2.7 1 1 0 2 2 2 2 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 CBY25104.1 - 0.02 15.4 1.6 8.5 7.0 0.0 4.3 7 0 0 7 7 7 0 HEAT-like repeat Gcn1_N PF12074.8 CBY25104.1 - 0.049 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Vac14_Fab1_bd PF12755.7 CBY25104.1 - 0.054 14.1 0.6 20 5.9 0.1 3.3 1 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region CHGN PF05679.16 CBY25105.1 - 9.5e-44 150.1 1.5 5.3e-40 137.7 1.5 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY25105.1 - 1.3e-08 34.4 1.0 2.9e-08 33.2 1.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Fringe PF02434.16 CBY25105.1 - 6.3e-08 32.4 0.0 1.9e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Fringe-like Glycos_transf_2 PF00535.26 CBY25105.1 - 0.0011 18.8 0.0 0.066 13.0 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBY25105.1 - 0.0026 17.7 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 YL1 PF05764.13 CBY25105.1 - 0.43 10.7 3.7 0.72 9.9 3.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein NHL PF01436.21 CBY25106.1 - 2.3e-22 77.8 9.4 6.8e-06 25.9 0.2 5.1 5 1 0 5 5 5 4 NHL repeat zf-met PF12874.7 CBY25107.1 - 1.3e-16 60.4 14.2 1.3e-08 34.9 1.4 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY25107.1 - 1.1e-11 44.6 12.0 1.2e-05 25.5 1.5 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY25107.1 - 2.8e-05 24.4 8.2 0.046 14.0 0.1 3.6 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBY25107.1 - 0.00036 21.1 3.7 0.071 14.0 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger betaPIX_CC PF16523.5 CBY25107.1 - 0.025 14.4 1.5 0.1 12.4 1.5 2.0 1 0 0 1 1 1 0 betaPIX coiled coil AKAP95 PF04988.12 CBY25107.1 - 0.026 14.8 10.4 0.46 10.7 0.1 3.3 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-U1 PF06220.12 CBY25107.1 - 0.063 13.1 7.5 0.28 11.0 0.2 3.3 3 0 0 3 3 3 0 U1 zinc finger DUF4407 PF14362.6 CBY25107.1 - 0.8 9.0 7.8 1.6 8.0 7.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Actin_micro PF17003.5 CBY25107.1 - 1.2 8.2 6.2 9.8 5.2 0.0 2.9 2 1 1 3 3 3 0 Putative actin-like family zf-C2H2 PF00096.26 CBY25107.1 - 2.1 9.0 4.6 0.92 10.1 1.0 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type FANCI_S3 PF14677.6 CBY25108.1 - 0.018 14.8 0.4 0.028 14.1 0.4 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 DUF4604 PF15377.6 CBY25109.1 - 0.0012 19.4 10.4 0.0012 19.4 10.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) PTPRCAP PF15713.5 CBY25109.1 - 6.1 7.1 10.9 8.2 6.7 10.9 1.3 1 1 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated GCFC PF07842.12 CBY25110.1 - 4e-05 23.4 0.1 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein DUF3827 PF12877.7 CBY25110.1 - 0.0011 17.4 1.2 0.0011 17.4 1.2 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3827) Prefoldin_2 PF01920.20 CBY25110.1 - 0.014 15.3 0.3 0.061 13.3 0.3 2.1 1 0 0 1 1 1 0 Prefoldin subunit HMMR_N PF15905.5 CBY25110.1 - 0.015 14.8 0.5 0.015 14.8 0.5 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spc24 PF08286.11 CBY25110.1 - 0.098 12.9 1.8 0.35 11.1 1.8 1.9 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Vac_Fusion PF02346.16 CBY25110.1 - 0.19 11.4 1.1 0.73 9.5 0.5 2.3 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 XhlA PF10779.9 CBY25110.1 - 0.46 10.7 6.6 0.13 12.4 2.7 2.1 2 0 0 2 2 2 0 Haemolysin XhlA V-ATPase_H_N PF03224.14 CBY25111.1 - 7.4e-68 229.1 8.0 7.4e-68 229.1 8.0 1.7 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CBY25111.1 - 4.3e-44 149.4 0.4 4.3e-44 149.4 0.4 2.5 3 1 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 CBY25111.1 - 0.00054 19.9 1.2 0.51 10.5 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CBY25111.1 - 0.012 16.0 0.2 3.5 8.1 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats DUF4230 PF14014.6 CBY25111.1 - 0.028 14.7 0.6 0.062 13.6 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) WD40 PF00400.32 CBY25112.1 - 9.4e-09 35.8 3.9 0.019 15.8 0.6 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY25112.1 - 0.00045 20.5 0.1 1.1 9.6 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DNA_ligase_A_M PF01068.21 CBY25113.1 - 4e-61 206.2 0.1 7.4e-61 205.4 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CBY25113.1 - 3.2e-41 141.5 0.0 1.1e-40 139.8 0.0 2.0 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CBY25113.1 - 1.1e-18 67.7 0.3 7.8e-18 64.9 0.0 2.8 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region FG-GAP_2 PF14312.6 CBY25113.1 - 0.21 11.9 0.6 0.45 10.8 0.6 1.5 1 0 0 1 1 1 0 FG-GAP repeat TMF_TATA_bd PF12325.8 CBY25114.1 - 1.6e-05 25.1 2.7 0.021 15.1 0.1 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 CBY25114.1 - 0.004 17.2 0.4 2.2 8.4 0.1 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein HALZ PF02183.18 CBY25114.1 - 0.0051 17.0 2.3 0.7 10.2 0.3 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 CBY25114.1 - 0.0069 16.4 5.0 0.21 11.6 1.0 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.21 CBY25114.1 - 0.0075 16.3 2.9 2.4 8.3 0.1 2.5 2 1 1 3 3 3 2 bZIP transcription factor Fungal_TACC PF12709.7 CBY25114.1 - 0.0076 16.7 1.8 1.1 9.8 0.2 2.3 2 0 0 2 2 2 1 Fungal Transforming acidic coiled-coil (TACC) proteins Cep57_CLD_2 PF14197.6 CBY25114.1 - 0.0078 16.3 4.7 0.22 11.6 0.3 2.5 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.8 CBY25114.1 - 0.0082 16.1 5.7 0.088 12.8 0.3 2.4 3 0 0 3 3 2 1 TATA element modulatory factor 1 DNA binding DUF4618 PF15397.6 CBY25114.1 - 0.01 15.3 5.0 0.31 10.4 0.6 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) ABC_tran_CTD PF16326.5 CBY25114.1 - 0.01 16.0 2.0 0.34 11.2 0.4 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain Fez1 PF06818.15 CBY25114.1 - 0.011 16.2 1.4 0.013 15.9 1.4 1.2 1 0 0 1 1 1 0 Fez1 FapA PF03961.13 CBY25114.1 - 0.011 14.4 1.7 0.012 14.2 1.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ZapB PF06005.12 CBY25114.1 - 0.017 15.5 2.6 0.35 11.3 0.1 2.3 2 0 0 2 2 2 0 Cell division protein ZapB LPP PF04728.13 CBY25114.1 - 0.019 15.4 1.5 4.4 7.8 0.4 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper TLE_N PF03920.15 CBY25114.1 - 0.02 15.0 3.8 0.31 11.1 0.2 2.1 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Spc24 PF08286.11 CBY25114.1 - 0.02 15.2 5.1 0.37 11.0 0.4 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CLZ PF16526.5 CBY25114.1 - 0.02 15.2 2.8 0.99 9.8 0.2 2.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 CBY25114.1 - 0.03 14.3 6.4 0.35 10.9 1.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2046 PF09755.9 CBY25114.1 - 0.037 13.3 4.0 0.15 11.2 1.3 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Csm1_N PF18504.1 CBY25114.1 - 0.048 14.0 2.8 6.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF5082 PF16888.5 CBY25114.1 - 0.051 13.9 3.1 3.9 7.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) FlxA PF14282.6 CBY25114.1 - 0.052 13.6 5.8 0.085 12.8 5.2 1.7 1 1 1 2 2 2 0 FlxA-like protein DivIC PF04977.15 CBY25114.1 - 0.054 13.3 2.7 2 8.3 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF2802 PF10975.8 CBY25114.1 - 0.067 13.3 4.2 0.18 11.9 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) Lectin_N PF03954.14 CBY25114.1 - 0.075 12.8 1.1 0.15 11.8 1.1 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain APG6_N PF17675.1 CBY25114.1 - 0.079 13.5 4.3 0.99 9.9 0.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF5320 PF17253.2 CBY25114.1 - 0.09 13.8 1.0 17 6.6 0.1 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF1184 PF06683.11 CBY25114.1 - 0.099 12.1 0.6 0.21 11.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1184) GAS PF13851.6 CBY25114.1 - 0.15 11.4 5.6 0.75 9.1 5.6 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Vps51 PF08700.11 CBY25114.1 - 0.19 11.8 4.6 0.89 9.7 0.4 2.7 3 0 0 3 3 3 0 Vps51/Vps67 Snapin_Pallidin PF14712.6 CBY25114.1 - 0.19 12.2 5.3 1.9 9.0 0.9 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF4363 PF14276.6 CBY25114.1 - 0.19 11.8 3.1 1.3 9.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DUF1640 PF07798.11 CBY25114.1 - 0.2 11.7 4.6 0.58 10.2 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Snf7 PF03357.21 CBY25114.1 - 0.2 11.2 6.4 0.24 11.0 6.4 1.2 1 0 0 1 1 1 0 Snf7 SOGA PF11365.8 CBY25114.1 - 0.2 12.8 3.6 0.46 11.6 1.9 2.0 1 1 1 2 2 2 0 Protein SOGA DUF1664 PF07889.12 CBY25114.1 - 0.22 11.5 4.5 5 7.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 CBY25114.1 - 0.27 9.1 2.7 0.31 8.9 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 CBY25114.1 - 0.28 11.6 6.7 4 7.9 0.6 3.0 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Mod_r PF07200.13 CBY25114.1 - 0.43 10.7 6.0 2.4 8.3 5.9 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Osmo_CC PF08946.10 CBY25114.1 - 0.64 10.3 7.3 2.2 8.6 0.1 3.0 2 1 1 3 3 3 0 Osmosensory transporter coiled coil Tup_N PF08581.10 CBY25114.1 - 0.75 10.1 6.0 11 6.4 0.3 2.7 2 1 1 3 3 3 0 Tup N-terminal DMPK_coil PF08826.10 CBY25114.1 - 0.79 9.9 6.5 0.3 11.2 1.6 2.4 2 1 1 3 3 3 0 DMPK coiled coil domain like EMP24_GP25L PF01105.24 CBY25114.1 - 0.85 9.5 4.7 3.2 7.7 0.7 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD bZIP_2 PF07716.15 CBY25114.1 - 1.1 9.4 3.5 21 5.3 0.3 2.5 2 1 0 2 2 2 0 Basic region leucine zipper DUF903 PF06004.12 CBY25115.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) V_ATPase_I PF01496.19 CBY25115.1 - 0.32 8.8 3.4 0.41 8.5 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CBY25115.1 - 3.3 6.9 5.6 5.5 6.1 5.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein AAA_23 PF13476.6 CBY25115.1 - 3.9 7.9 10.7 6.5 7.2 10.7 1.3 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 CBY25115.1 - 4.3 5.8 6.0 6 5.3 6.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CUB PF00431.20 CBY25116.1 - 1.5e-23 83.3 0.0 2.6e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 CUB domain CUB_2 PF02408.20 CBY25116.1 - 6.3e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 CUB-like domain Trypsin PF00089.26 CBY25117.1 - 9.2e-52 176.0 0.0 1.3e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY25117.1 - 5.1e-05 24.2 0.0 0.00014 22.8 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY25117.1 - 0.0019 18.6 0.0 0.006 17.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) TIL PF01826.17 CBY25117.1 - 0.0029 17.8 3.8 0.0033 17.6 1.7 2.2 2 0 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain NAD_binding_10 PF13460.6 CBY25118.1 - 0.038 13.9 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Ank_2 PF12796.7 CBY25119.1 - 2.2e-46 156.4 1.0 1.9e-11 44.4 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY25119.1 - 4.2e-34 116.5 1.3 2.5e-08 34.3 0.0 8.1 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY25119.1 - 9.2e-26 89.6 4.5 0.00012 22.3 0.0 7.9 2 2 7 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY25119.1 - 3.5e-22 76.1 0.5 0.013 16.0 0.0 10.9 12 0 0 12 12 10 4 Ankyrin repeat Ank PF00023.30 CBY25119.1 - 5.2e-22 77.3 0.6 0.023 15.1 0.0 9.5 8 1 0 8 8 8 4 Ankyrin repeat NACHT PF05729.12 CBY25119.1 - 4e-05 23.6 1.1 0.33 10.9 0.0 2.9 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 CBY25119.1 - 0.00053 20.4 0.2 0.011 16.1 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 CBY25119.1 - 0.081 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CBY25119.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 CBY25119.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 CBY25119.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 CBY25119.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 CBY25119.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CBY25119.1 - 0.21 10.7 0.0 0.46 9.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Miff PF05644.11 CBY25120.1 - 2.9e-08 33.7 8.2 1.4e-05 24.9 1.0 2.4 1 1 1 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff Cluap1 PF10234.9 CBY25120.1 - 0.0021 17.5 4.7 0.0057 16.1 2.5 2.0 2 0 0 2 2 2 1 Clusterin-associated protein-1 Cauli_AT PF03233.13 CBY25120.1 - 0.12 12.3 2.7 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 Aphid transmission protein Nefa_Nip30_N PF10187.9 CBY25122.1 - 3e-21 75.7 8.8 4.1e-21 75.3 8.8 1.2 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Ion_trans_N PF08412.10 CBY25122.1 - 4.1 7.1 5.1 4.4 7.0 0.2 2.7 2 0 0 2 2 2 0 Ion transport protein N-terminal PMSR PF01625.21 CBY25123.1 - 6.8e-57 191.9 1.1 8.1e-57 191.7 1.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase G_path_suppress PF15991.5 CBY25123.1 - 0.031 14.4 0.1 0.039 14.1 0.1 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor GAS PF13851.6 CBY25124.1 - 3.3e-05 23.3 2.5 6e-05 22.5 2.5 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding HIP1_clath_bdg PF16515.5 CBY25124.1 - 0.0024 18.4 2.1 0.0082 16.7 2.1 1.9 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 CBY25124.1 - 0.0058 17.2 4.3 0.011 16.2 4.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region FapA PF03961.13 CBY25124.1 - 0.025 13.2 1.6 0.035 12.7 1.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lectin_N PF03954.14 CBY25124.1 - 0.055 13.2 4.8 2.9 7.6 0.1 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain YabA PF06156.13 CBY25124.1 - 1.1 9.9 4.2 1.2 9.8 2.7 1.9 2 0 0 2 2 2 0 Initiation control protein YabA TPD52 PF04201.15 CBY25124.1 - 7.8 6.1 9.7 11 5.5 5.6 2.7 2 1 0 2 2 2 0 Tumour protein D52 family Mg_trans_NIPA PF05653.14 CBY25125.1 - 7.2e-126 419.3 15.5 8.4e-126 419.0 15.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CBY25125.1 - 4.1e-07 30.2 4.3 4.1e-07 30.2 4.3 3.7 3 1 0 3 3 3 1 EamA-like transporter family FtsX PF02687.21 CBY25125.1 - 0.051 14.1 0.9 0.051 14.1 0.9 4.2 2 1 1 4 4 4 0 FtsX-like permease family YibE_F PF07907.11 CBY25125.1 - 0.42 10.1 24.3 0.16 11.5 2.1 3.3 3 0 0 3 3 3 0 YibE/F-like protein Methyltransf_16 PF10294.9 CBY25126.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DHFR_1 PF00186.19 CBY25127.1 - 2e-33 115.4 0.0 2.4e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Histone PF00125.24 CBY25129.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY25129.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY25129.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY25129.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY25129.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SET PF00856.28 CBY25130.1 - 5e-14 53.0 0.3 1.4e-11 45.0 0.1 3.2 2 1 1 3 3 3 2 SET domain Chromo PF00385.24 CBY25130.1 - 4e-05 23.5 0.4 0.00015 21.6 0.4 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LigT_PEase PF02834.16 CBY25130.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF1450 PF07293.11 CBY25130.1 - 0.98 9.3 5.4 0.13 12.1 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1450) zf-UBR PF02207.20 CBY25131.1 - 0.022 14.9 6.3 0.043 14.0 6.3 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) FliJ PF02050.16 CBY25132.1 - 0.0039 17.4 8.8 0.0054 16.9 8.8 1.2 1 0 0 1 1 1 1 Flagellar FliJ protein CHGN PF05679.16 CBY25133.1 - 5.4e-56 190.5 11.6 2.7e-37 128.8 0.8 2.4 3 0 0 3 3 3 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY25133.1 - 1.6e-16 60.6 0.4 1.3e-15 57.6 0.1 2.4 2 1 0 2 2 2 1 Fringe-like Glyco_transf_7C PF02709.14 CBY25133.1 - 1e-09 37.9 0.5 2.5e-09 36.7 0.5 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY25133.1 - 0.00016 21.5 0.3 0.074 12.9 0.1 2.5 3 0 0 3 3 3 2 Glycosyl transferase family 2 Galactosyl_T PF01762.21 CBY25133.1 - 0.00017 21.5 0.0 0.013 15.3 0.0 2.8 3 0 0 3 3 3 1 Galactosyltransferase Glyco_transf_21 PF13506.6 CBY25133.1 - 0.092 12.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 VWD PF00094.25 CBY25135.1 - 1.3e-22 80.7 0.1 1.9e-22 80.2 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 CBY25135.1 - 6.6e-17 61.7 4.4 6.6e-17 61.7 4.4 2.7 2 1 1 3 3 3 1 C8 domain TIL PF01826.17 CBY25135.1 - 1.2e-09 38.3 17.6 1.2e-09 38.3 17.6 3.8 4 2 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 CBY25135.1 - 4.9e-06 26.4 10.8 4.9e-06 26.4 10.8 3.4 1 1 1 2 2 2 1 TILa domain Helicase_C PF00271.31 CBY25136.1 - 4.7e-11 43.0 0.0 8.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 CBY25137.1 - 1.6e-10 41.4 0.7 0.039 14.8 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY25137.1 - 1.4e-05 25.2 0.2 4.3 7.7 0.0 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY25137.1 - 0.031 13.6 0.0 4.5 6.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Vps53_N PF04100.12 CBY25138.1 - 1.6e-101 340.0 12.5 2.8e-101 339.2 12.5 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 CBY25138.1 - 8.8e-05 21.9 4.8 0.0003 20.2 4.5 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF4855 PF16147.5 CBY25138.1 - 0.13 11.4 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) DUF1366 PF07104.11 CBY25138.1 - 0.14 11.9 1.5 0.46 10.2 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) MnmE_helical PF12631.7 CBY25138.1 - 0.5 10.5 11.5 0.21 11.8 7.6 2.4 2 1 0 2 2 2 0 MnmE helical domain Sec8_exocyst PF04048.14 CBY25138.1 - 0.51 10.2 6.1 0.21 11.5 2.0 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain MCPsignal PF00015.21 CBY25138.1 - 0.59 9.9 6.3 0.31 10.8 3.4 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ABC_tran_CTD PF16326.5 CBY25138.1 - 1.1 9.5 7.6 25 5.2 0.0 4.0 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF489 PF04356.12 CBY25138.1 - 2.4 8.1 8.2 14 5.6 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF489) WD40 PF00400.32 CBY25139.1 - 2.1e-25 88.5 10.9 6.7e-10 39.4 0.5 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY25139.1 - 2.9e-08 33.9 0.0 0.019 15.3 0.0 3.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY25139.1 - 3.8e-05 22.8 0.3 0.47 9.4 0.1 3.0 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBY25139.1 - 0.00011 22.1 0.0 0.0017 18.3 0.0 1.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CBY25139.1 - 0.00052 18.8 0.3 0.001 17.8 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Tudor_3 PF18115.1 CBY25141.1 - 8.9e-06 25.5 0.7 0.00034 20.4 0.2 2.4 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 CBY25141.1 - 0.0061 16.6 0.1 0.017 15.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) dsrm PF00035.26 CBY25144.1 - 4.4e-33 113.8 17.1 3.6e-10 40.4 0.6 6.3 6 0 0 6 6 6 4 Double-stranded RNA binding motif Staufen_C PF16482.5 CBY25144.1 - 6.4e-20 71.4 0.5 6.6e-19 68.1 0.1 2.6 3 0 0 3 3 3 1 Staufen C-terminal domain Mito_carr PF00153.27 CBY25144.1 - 4.3e-19 68.2 0.0 6.7e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial carrier protein DND1_DSRM PF14709.7 CBY25144.1 - 0.15 12.3 11.5 1.9 8.8 0.0 4.6 5 0 0 5 5 5 0 double strand RNA binding domain from DEAD END PROTEIN 1 Phospholip_A2_1 PF00068.19 CBY25148.1 - 3e-16 59.9 9.0 4e-16 59.5 9.0 1.2 1 0 0 1 1 1 1 Phospholipase A2 Ifi-6-16 PF06140.13 CBY25149.1 - 3.9e-09 36.3 32.4 3.9e-09 36.3 32.4 2.3 1 1 1 2 2 2 1 Interferon-induced 6-16 family UL45 PF05473.12 CBY25150.1 - 0.057 13.1 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF1517 PF07466.11 CBY25150.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Lectin_C PF00059.21 CBY25150.1 - 0.21 12.4 1.5 27 5.6 1.7 2.6 1 1 1 2 2 2 0 Lectin C-type domain Kelch_6 PF13964.6 CBY25150.1 - 0.34 11.3 3.9 0.45 10.9 0.0 2.9 3 0 0 3 3 3 0 Kelch motif DUF5524 PF17662.1 CBY25155.1 - 0.012 15.0 0.8 0.014 14.8 0.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5524) RRM_1 PF00076.22 CBY25156.1 - 0.13 12.1 0.1 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CBY25157.1 - 6.2e-15 55.3 0.0 1.3e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY25157.1 - 1.7e-11 43.9 0.0 4.1e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase NUC173 PF08161.12 CBY25157.1 - 0.03 14.0 0.2 0.073 12.7 0.2 1.6 1 0 0 1 1 1 0 NUC173 domain Rcd1 PF04078.13 CBY25157.1 - 0.097 11.9 0.1 0.27 10.5 0.1 1.7 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like PARP PF00644.20 CBY25158.1 - 4.8e-56 189.4 0.0 4.8e-56 189.4 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CBY25158.1 - 1.4e-38 132.1 1.4 2.4e-38 131.3 0.6 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CBY25158.1 - 5e-22 77.8 0.8 1.2e-21 76.5 0.8 1.7 1 0 0 1 1 1 1 WGR domain RNA_pol_Rpc4 PF05132.14 CBY25159.1 - 9.8e-07 29.3 3.7 9.6e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase III RPC4 API5 PF05918.11 CBY25159.1 - 3.8 6.2 6.3 6.3 5.5 6.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GSHPx PF00255.19 CBY25160.1 - 3.4e-10 39.4 0.1 4.4e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Peptidase_C10 PF01640.17 CBY25160.1 - 0.1 12.9 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C10 family MH2 PF03166.14 CBY25161.1 - 2.9e-37 128.7 0.7 2.9e-37 128.7 0.7 1.4 2 0 0 2 2 2 1 MH2 domain Troponin PF00992.20 CBY25162.1 - 2.4e-23 82.9 42.6 1.3e-22 80.5 37.9 2.0 1 1 1 2 2 2 2 Troponin DUF262 PF03235.14 CBY25162.1 - 4.4 7.4 12.2 6.3 6.9 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 AdoHcyase PF05221.17 CBY25164.1 - 1.7e-118 395.2 0.0 9.4e-65 218.7 0.1 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CBY25164.1 - 5.1e-77 257.5 2.9 8.1e-77 256.8 2.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CBY25164.1 - 1.1e-08 34.7 0.2 2.1e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBY25164.1 - 3.9e-06 26.5 0.1 6.6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 CBY25164.1 - 0.00053 19.4 2.3 0.0017 17.7 2.3 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.21 CBY25164.1 - 0.0018 17.6 1.9 0.0051 16.1 1.9 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CBY25164.1 - 0.0038 17.6 0.5 0.019 15.4 0.3 2.2 2 1 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.18 CBY25164.1 - 0.046 14.0 0.5 0.18 12.1 0.5 2.0 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 CBY25164.1 - 0.069 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 CBY25164.1 - 0.18 11.5 0.9 1.1 8.9 0.8 2.0 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IF4E PF01652.18 CBY25165.1 - 3.9e-41 140.5 0.5 5.1e-41 140.1 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E FA PF08736.11 CBY25166.1 - 0.044 13.9 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 FERM adjacent (FA) O-FucT PF10250.9 CBY25167.1 - 1.9e-08 34.4 0.0 5.5e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Kelch_4 PF13418.6 CBY25168.1 - 2.5e-09 37.0 1.0 0.0057 16.6 0.1 3.4 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY25168.1 - 2.2e-06 27.7 5.1 0.22 11.9 0.2 3.9 2 1 1 3 3 3 3 Kelch motif Kelch_1 PF01344.25 CBY25168.1 - 5.5e-05 22.7 3.3 0.2 11.3 0.4 3.3 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CBY25168.1 - 0.00078 19.3 0.8 0.25 11.4 0.1 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CBY25168.1 - 0.26 11.3 3.0 1.1 9.3 0.2 2.9 3 0 0 3 3 3 0 Kelch motif Sulfotransfer_1 PF00685.27 CBY25170.1 - 1.9e-12 47.2 0.1 3.7e-12 46.3 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY25170.1 - 0.0012 19.3 0.0 0.27 11.6 0.0 2.9 1 1 2 3 3 3 1 Sulfotransferase family Kelch_2 PF07646.15 CBY25171.1 - 0.084 12.9 1.5 18 5.5 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 CBY25171.1 - 0.09 12.8 6.8 0.18 11.8 0.0 4.0 5 0 0 5 5 5 0 Kelch motif Kelch_6 PF13964.6 CBY25171.1 - 0.16 12.3 5.4 12 6.4 0.0 4.4 3 2 1 4 4 4 0 Kelch motif Na_Ca_ex PF01699.24 CBY25172.1 - 4.5e-32 111.1 19.3 5.1e-32 110.9 19.3 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Cadherin_C_2 PF16492.5 CBY25172.1 - 0.0064 17.2 1.1 0.0064 17.2 1.1 1.6 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal DUF5082 PF16888.5 CBY25173.1 - 0.048 13.9 1.5 0.18 12.1 1.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) API5 PF05918.11 CBY25173.1 - 0.2 10.4 8.2 0.34 9.7 8.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PRTP PF01366.18 CBY25173.1 - 0.23 9.5 2.9 0.31 9.1 0.2 2.1 2 1 0 2 2 2 0 Herpesvirus processing and transport protein ATP-grasp_6 PF18419.1 CBY25174.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp-like domain PMT_4TMC PF16192.5 CBY25175.1 - 0.0099 15.5 1.7 0.0099 15.5 1.7 1.8 1 1 1 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Tunicata/Oikopleura_dioica-ASM20953v1/GCA_000209535.1_ASM20953v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Tunicata/Oikopleura_dioica-ASM20953v1/GCA_000209535.1_ASM20953v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Tunicata/Oikopleura_dioica-ASM20953v1/GCA_000209535.1_ASM20953v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Tunicata/Oikopleura_dioica-ASM20953v1/GCA_000209535.1_ASM20953v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 21:56:58 2019 # [ok]